PT97460A - Processo para a preparacao de compostos anti-virus derivados de acido d-neuraminico e das suas formulacoes farmaceuticas - Google Patents
Processo para a preparacao de compostos anti-virus derivados de acido d-neuraminico e das suas formulacoes farmaceuticasInfo
- Publication number
- PT97460A PT97460A PT97460A PT9746091A PT97460A PT 97460 A PT97460 A PT 97460A PT 97460 A PT97460 A PT 97460A PT 9746091 A PT9746091 A PT 9746091A PT 97460 A PT97460 A PT 97460A
- Authority
- PT
- Portugal
- Prior art keywords
- group
- nhr6
- designates
- preparation
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ980090 | 1990-04-24 | ||
AUPK289690 | 1990-10-19 | ||
AUPK453791 | 1991-02-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT97460A true PT97460A (pt) | 1992-01-31 |
PT97460B PT97460B (pt) | 1999-01-29 |
Family
ID=27157556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97460A PT97460B (pt) | 1990-04-24 | 1991-04-24 | Processo para a preparacao de compostos anti-virus derivados de acido d-neuraminico e das suas formulacoes farmaceuticas |
Country Status (37)
Country | Link |
---|---|
US (2) | US5360817A (pt) |
EP (2) | EP0786458B1 (pt) |
JP (1) | JP2944750B2 (pt) |
KR (1) | KR0169496B1 (pt) |
CN (3) | CN1143853C (pt) |
AP (1) | AP249A (pt) |
AT (2) | ATE161253T1 (pt) |
AU (2) | AU654815B2 (pt) |
BG (1) | BG62092B1 (pt) |
CA (2) | CA2081356C (pt) |
CY (1) | CY2186B1 (pt) |
CZ (1) | CZ288492B6 (pt) |
DE (3) | DE19975068I2 (pt) |
DK (1) | DK0526543T3 (pt) |
ES (2) | ES2113881T3 (pt) |
FI (2) | FI105478B (pt) |
GR (1) | GR3026225T3 (pt) |
HK (2) | HK1003834A1 (pt) |
HU (2) | HU219355B (pt) |
IE (2) | IE911372A1 (pt) |
IL (1) | IL97936A (pt) |
LU (1) | LU90468I2 (pt) |
MY (1) | MY107843A (pt) |
NL (1) | NL990030I2 (pt) |
NO (3) | NO302751B1 (pt) |
NZ (1) | NZ237936A (pt) |
OA (1) | OA09679A (pt) |
PL (3) | PL167630B1 (pt) |
PT (1) | PT97460B (pt) |
RU (1) | RU2119487C1 (pt) |
SG (1) | SG43170A1 (pt) |
SI (1) | SI9110745B (pt) |
SK (1) | SK282950B6 (pt) |
UA (1) | UA41252C2 (pt) |
WO (1) | WO1991016320A1 (pt) |
YU (1) | YU48741B (pt) |
ZA (1) | ZA913086B (pt) |
Families Citing this family (132)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2081068C (en) * | 1991-10-23 | 2005-11-29 | Laurence Mark Von Itzstein | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid |
GB9126725D0 (en) * | 1991-12-17 | 1992-02-12 | Glaxo Group Ltd | Process |
GB9220241D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
GB9220327D0 (en) * | 1992-09-25 | 1992-11-11 | Glaxo Group Ltd | Process |
GB9312531D0 (en) * | 1993-06-17 | 1993-08-04 | Glaxo Group Ltd | Process |
US5958973A (en) * | 1993-09-03 | 1999-09-28 | Gilead Sciences, Inc. | Polyhydroxy benzoic acid derivatives and their use as neuraminidase inhibitors |
GB9325841D0 (en) * | 1993-12-17 | 1994-02-23 | Glaxo Group Ltd | Chemical compounds |
GB9400206D0 (en) * | 1994-01-07 | 1994-03-02 | Glaxo Group Ltd | Chemical compound |
AUPM354694A0 (en) * | 1994-01-27 | 1994-02-17 | Biota Scientific Management Pty Ltd | Chemical compounds |
US5985859A (en) * | 1994-04-14 | 1999-11-16 | The University Of Alabama | Methods of inhibiting bacterial sialidase |
US5453533A (en) * | 1994-04-14 | 1995-09-26 | The University Of Alabama At Birmingham | Inhibitors of influenza virus neuraminidase and methods of making and using the same |
JP3648740B2 (ja) * | 1994-05-27 | 2005-05-18 | ダイキン工業株式会社 | 7位をフッ素で置換した2,3−ジデヒドロシアル酸およびその合成中間体 |
GB9410817D0 (en) * | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
AUPM725794A0 (en) * | 1994-08-03 | 1994-08-25 | Biota Scientific Management Pty Ltd | Chemical compounds |
US5556963A (en) * | 1994-08-05 | 1996-09-17 | Oklahoma Medical Research Foundation | Synthesis of 4-alkoxy-N-acetylneuraminic acid |
GB9416365D0 (en) * | 1994-08-12 | 1994-10-05 | Glaxo Group Ltd | Medicaments |
US5512596A (en) * | 1994-09-02 | 1996-04-30 | Gilead Sciences, Inc. | Aromatic compounds |
US5475109A (en) * | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
CN100338031C (zh) * | 1995-02-27 | 2007-09-19 | 吉里德科学公司 | 新颖化合物,其合成方法及治疗用途 |
US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
WO1996026933A1 (en) * | 1995-02-27 | 1996-09-06 | Gilead Sciences, Inc. | Novel selective inhibitors of viral or bacterial neuraminidases |
CN101172957B (zh) * | 1995-02-27 | 2012-11-14 | 吉里德科学公司 | 新颖化合物,其合成方法及治疗用途 |
AU4259500A (en) * | 1995-02-27 | 2000-08-31 | Gilead Sciences, Inc. | Novel compounds and methods for synthesis and therapy |
US5602277A (en) * | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
US5714509A (en) * | 1995-05-03 | 1998-02-03 | The University Of Alabama | Inhibitors of bacterial sialidase and methods of making and using the same |
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GB9516276D0 (en) * | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
JPH0967270A (ja) * | 1995-08-31 | 1997-03-11 | Res Dev Corp Of Japan | 水晶体混濁の予防および治療法、並びにそのための薬 剤 |
US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
HU223099B1 (hu) * | 1996-03-01 | 2004-03-29 | Biota Scientific Managemant Pty. Ltd. | Eljárás influenzavírus kimutatására és az eljárásban alkalmazható vegyületek |
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US20030129146A1 (en) * | 1997-10-31 | 2003-07-10 | Vincent Fischetti | The use of bacterial phage associated lysing proteins for treating bacterial dental caries |
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US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
TWI736523B (zh) | 2015-01-24 | 2021-08-21 | 中央研究院 | 新穎聚醣結合物及其使用方法 |
US10336784B2 (en) | 2016-03-08 | 2019-07-02 | Academia Sinica | Methods for modular synthesis of N-glycans and arrays thereof |
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CN106520864A (zh) * | 2016-09-28 | 2017-03-22 | 南京农业大学 | 一种酶法合成唾液酸类似物的方法及其应用 |
AU2018273411B2 (en) * | 2017-05-25 | 2022-12-01 | The Governors Of The University Of Alberta | Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase |
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AU2022422584A1 (en) | 2021-12-23 | 2024-05-30 | Subintro Limited | Novel antiviral compositions comprising oleic acid |
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