YU74591A - Anti-virusna jedinjenja - Google Patents

Anti-virusna jedinjenja

Info

Publication number
YU74591A
YU74591A YU74591A YU74591A YU74591A YU 74591 A YU74591 A YU 74591A YU 74591 A YU74591 A YU 74591A YU 74591 A YU74591 A YU 74591A YU 74591 A YU74591 A YU 74591A
Authority
YU
Yugoslavia
Prior art keywords
formula
product
treatment
compounds
viral
Prior art date
Application number
YU74591A
Other languages
English (en)
Serbian (sr)
Other versions
YU48741B (sh
Inventor
T.M. Von Itzstein
W.Y. Wu
T.V. Phan
B. Jin
Original Assignee
Biota Scientific Management Pty Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scientific Management Pty Ltd. filed Critical Biota Scientific Management Pty Ltd.
Priority to SI9110745A priority Critical patent/SI9110745B/sl
Priority to HRP-745/91A priority patent/HRP930455B1/xx
Publication of YU74591A publication Critical patent/YU74591A/sh
Publication of YU48741B publication Critical patent/YU48741B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

ANTI-VIRUSNA JEDINJENJA, pronalazak se odnosi na analoge 2-dezoksi-2,3-didehidro-N-acetilneuraminske kiseline formule (I) ili (Ia): gde su A, R1, R2, R3, R3', R4 i R5 definisani u patentnim zahtevima, na farmaceutske preparate koji ih sadrže i na njihovu primenu u proizvodnji lekova za tretiranje virusnih infekcija, a naročito za tretirnje influence. Pronalazak obuhvata i postupak za dobijanje jedinjenja formule (I) i (Ia), u kome jedinjenje formule (III): gde su A, R1, R2, R4 i R5 kao što je definisano u patentnim zahtevima, a L je odlazeća grupa, reaguje sa nukleofilom, nakon čega dobijeni proizvod formule (I) ili (Ia) može da se prevede u drugi proizvod formule (I) ili (Ia) da bi se, na kraju, uklonile prisutne zaštitne grupe i proizvod, po potrebi, preveo u svoju farmaceutski prihvatljivu so.
YU74591A 1990-04-24 1991-04-24 Derivati i analozi 2-dezoksi-2,3-didehidro-n-acetil-neuraminske kiseline i postupak za njihovo dobijanje YU48741B (sh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI9110745A SI9110745B (en) 1990-04-24 1991-04-24 Anti-viral compounds.
HRP-745/91A HRP930455B1 (en) 1990-04-24 1993-03-23 Antiviral compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPJ980090 1990-04-24
AUPK289690 1990-10-19
AUPK453791 1991-02-11

Publications (2)

Publication Number Publication Date
YU74591A true YU74591A (sh) 1994-06-24
YU48741B YU48741B (sh) 1999-09-27

Family

ID=27157556

Family Applications (1)

Application Number Title Priority Date Filing Date
YU74591A YU48741B (sh) 1990-04-24 1991-04-24 Derivati i analozi 2-dezoksi-2,3-didehidro-n-acetil-neuraminske kiseline i postupak za njihovo dobijanje

Country Status (37)

Country Link
US (2) US5360817A (sh)
EP (2) EP0786458B1 (sh)
JP (1) JP2944750B2 (sh)
KR (1) KR0169496B1 (sh)
CN (3) CN1036849C (sh)
AP (1) AP249A (sh)
AT (2) ATE161253T1 (sh)
AU (2) AU654815B2 (sh)
BG (1) BG62092B1 (sh)
CA (2) CA2081356C (sh)
CY (1) CY2186B1 (sh)
CZ (1) CZ288492B6 (sh)
DE (3) DE69128469T2 (sh)
DK (1) DK0526543T3 (sh)
ES (2) ES2313730T3 (sh)
FI (2) FI105478B (sh)
GR (1) GR3026225T3 (sh)
HK (2) HK1003834A1 (sh)
HU (2) HU219355B (sh)
IE (2) IE911372A1 (sh)
IL (1) IL97936A (sh)
LU (1) LU90468I2 (sh)
MY (1) MY107843A (sh)
NL (1) NL990030I2 (sh)
NO (3) NO302751B1 (sh)
NZ (1) NZ237936A (sh)
OA (1) OA09679A (sh)
PL (3) PL166918B1 (sh)
PT (1) PT97460B (sh)
RU (1) RU2119487C1 (sh)
SG (1) SG43170A1 (sh)
SI (1) SI9110745B (sh)
SK (1) SK282950B6 (sh)
UA (1) UA41252C2 (sh)
WO (1) WO1991016320A1 (sh)
YU (1) YU48741B (sh)
ZA (1) ZA913086B (sh)

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