DK663588A - Purinderivater - Google Patents

Purinderivater

Info

Publication number
DK663588A
DK663588A DK663588A DK663588A DK663588A DK 663588 A DK663588 A DK 663588A DK 663588 A DK663588 A DK 663588A DK 663588 A DK663588 A DK 663588A DK 663588 A DK663588 A DK 663588A
Authority
DK
Denmark
Prior art keywords
alkyl
phenyl
chem
amino
hydrogen
Prior art date
Application number
DK663588A
Other languages
English (en)
Other versions
DK663588D0 (da
Inventor
Michael Raymond Harnden
David Malcolm Duckworth
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878727988A external-priority patent/GB8727988D0/en
Priority claimed from GB888811575A external-priority patent/GB8811575D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK663588D0 publication Critical patent/DK663588D0/da
Publication of DK663588A publication Critical patent/DK663588A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503Five-membered rings
    • C07F9/6506Five-membered rings having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/6512Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Jib Cranes (AREA)
  • Sub-Exchange Stations And Push- Button Telephones (AREA)
  • Liquid Crystal (AREA)
  • Electrically Driven Valve-Operating Means (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
DK663588A 1987-11-30 1988-11-28 Purinderivater DK663588A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878727988A GB8727988D0 (en) 1987-11-30 1987-11-30 Novel compounds
GB888811575A GB8811575D0 (en) 1988-05-16 1988-05-16 Novel compounds

Publications (2)

Publication Number Publication Date
DK663588D0 DK663588D0 (da) 1988-11-28
DK663588A true DK663588A (da) 1989-05-31

Family

ID=26293121

Family Applications (1)

Application Number Title Priority Date Filing Date
DK663588A DK663588A (da) 1987-11-30 1988-11-28 Purinderivater

Country Status (20)

Country Link
EP (1) EP0319228B1 (da)
JP (1) JPH02293A (da)
KR (1) KR890008141A (da)
AT (1) ATE113601T1 (da)
AU (1) AU617724B2 (da)
DE (1) DE3852008T2 (da)
DK (1) DK663588A (da)
ES (1) ES2064361T3 (da)
FI (1) FI885544A (da)
GR (1) GR3014910T3 (da)
HU (1) HU202244B (da)
IE (1) IE883550L (da)
IL (1) IL88518A (da)
MA (1) MA21450A1 (da)
MY (1) MY103502A (da)
NO (1) NO885313L (da)
NZ (1) NZ227104A (da)
PH (1) PH26927A (da)
PL (3) PL158762B1 (da)
PT (1) PT89098B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247085A (en) * 1987-11-30 1993-09-21 Beecham Group P.L.C. Antiviral purine compounds
EP0353955A3 (en) * 1988-08-02 1991-08-14 Beecham Group Plc Novel compounds
GB8907173D0 (en) * 1989-03-30 1989-05-10 Beecham Group Plc Novel compounds
GB8912043D0 (en) * 1989-05-25 1989-07-12 Beecham Group Plc Novel compounds
EP0405748A1 (en) * 1989-05-30 1991-01-02 Beecham Group p.l.c. Phosphonoderivative of purine with antiviral activity
US5208221A (en) * 1990-11-29 1993-05-04 Bristol-Myers Squibb Company Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives
GB9205917D0 (en) * 1992-03-18 1992-04-29 Smithkline Beecham Plc Pharmaceuticals
JPH09506333A (ja) * 1993-09-17 1997-06-24 ギリアード サイエンシーズ,インコーポレイテッド 治療化合物の投薬方法
US5798340A (en) * 1993-09-17 1998-08-25 Gilead Sciences, Inc. Nucleotide analogs
GB9821058D0 (en) 1998-09-28 1998-11-18 Univ Cardiff Chemical compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3646049A (en) * 1970-03-05 1972-02-29 Merck & Co Inc Acylaminobenzimidazole derivatives
CS263951B1 (en) * 1985-04-25 1989-05-12 Antonin Holy 9-(phosponylmethoxyalkyl)adenines and method of their preparation

Also Published As

Publication number Publication date
MA21450A1 (fr) 1989-07-01
HU202244B (en) 1991-02-28
AU2631188A (en) 1989-06-15
IL88518A (en) 1994-02-27
FI885544A0 (fi) 1988-11-29
PL160924B1 (en) 1993-05-31
EP0319228A3 (en) 1990-05-16
DE3852008T2 (de) 1995-03-23
DE3852008D1 (de) 1994-12-08
NO885313L (no) 1989-05-31
PT89098A (pt) 1988-12-01
ES2064361T3 (es) 1995-02-01
GR3014910T3 (en) 1995-05-31
JPH02293A (ja) 1990-01-05
PL276046A1 (en) 1990-01-08
PL158762B1 (en) 1992-10-30
DK663588D0 (da) 1988-11-28
IE883550L (en) 1989-05-30
PL281367A1 (en) 1990-05-28
EP0319228B1 (en) 1994-11-02
NO885313D0 (no) 1988-11-29
EP0319228A2 (en) 1989-06-07
PL281368A1 (en) 1990-05-28
FI885544A (fi) 1989-05-31
MY103502A (en) 1993-06-30
IL88518A0 (en) 1989-06-30
PH26927A (en) 1992-12-02
NZ227104A (en) 1991-11-26
AU617724B2 (en) 1991-12-05
KR890008141A (ko) 1989-07-10
ATE113601T1 (de) 1994-11-15
PT89098B (pt) 1993-03-31
HUT50352A (en) 1990-01-29
PL160927B1 (pl) 1993-05-31

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment