DK663588A - Purinderivater - Google Patents
PurinderivaterInfo
- Publication number
- DK663588A DK663588A DK663588A DK663588A DK663588A DK 663588 A DK663588 A DK 663588A DK 663588 A DK663588 A DK 663588A DK 663588 A DK663588 A DK 663588A DK 663588 A DK663588 A DK 663588A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- phenyl
- chem
- amino
- hydrogen
- Prior art date
Links
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 hydroxy, amino Chemical group 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Liquid Crystal (AREA)
- Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
- Electrically Driven Valve-Operating Means (AREA)
- Jib Cranes (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Sub-Exchange Stations And Push- Button Telephones (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878727988A GB8727988D0 (en) | 1987-11-30 | 1987-11-30 | Novel compounds |
| GB888811575A GB8811575D0 (en) | 1988-05-16 | 1988-05-16 | Novel compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK663588D0 DK663588D0 (da) | 1988-11-28 |
| DK663588A true DK663588A (da) | 1989-05-31 |
Family
ID=26293121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK663588A DK663588A (da) | 1987-11-30 | 1988-11-28 | Purinderivater |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0319228B1 (da) |
| JP (1) | JPH02293A (da) |
| KR (1) | KR890008141A (da) |
| AT (1) | ATE113601T1 (da) |
| AU (1) | AU617724B2 (da) |
| DE (1) | DE3852008T2 (da) |
| DK (1) | DK663588A (da) |
| ES (1) | ES2064361T3 (da) |
| FI (1) | FI885544A (da) |
| GR (1) | GR3014910T3 (da) |
| HU (1) | HU202244B (da) |
| IE (1) | IE883550L (da) |
| IL (1) | IL88518A (da) |
| MA (1) | MA21450A1 (da) |
| MY (1) | MY103502A (da) |
| NO (1) | NO885313L (da) |
| NZ (1) | NZ227104A (da) |
| PH (1) | PH26927A (da) |
| PL (3) | PL158762B1 (da) |
| PT (1) | PT89098B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5247085A (en) * | 1987-11-30 | 1993-09-21 | Beecham Group P.L.C. | Antiviral purine compounds |
| EP0353955A3 (en) * | 1988-08-02 | 1991-08-14 | Beecham Group Plc | Novel compounds |
| GB8907173D0 (en) * | 1989-03-30 | 1989-05-10 | Beecham Group Plc | Novel compounds |
| GB8912043D0 (en) * | 1989-05-25 | 1989-07-12 | Beecham Group Plc | Novel compounds |
| EP0405748A1 (en) * | 1989-05-30 | 1991-01-02 | Beecham Group p.l.c. | Phosphonoderivative of purine with antiviral activity |
| US5208221A (en) * | 1990-11-29 | 1993-05-04 | Bristol-Myers Squibb Company | Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives |
| GB9205917D0 (en) * | 1992-03-18 | 1992-04-29 | Smithkline Beecham Plc | Pharmaceuticals |
| US5798340A (en) | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
| JPH09506333A (ja) * | 1993-09-17 | 1997-06-24 | ギリアード サイエンシーズ，インコーポレイテッド | 治療化合物の投薬方法 |
| GB9821058D0 (en) | 1998-09-28 | 1998-11-18 | Univ Cardiff | Chemical compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3646049A (en) * | 1970-03-05 | 1972-02-29 | Merck & Co Inc | Acylaminobenzimidazole derivatives |
| CS263951B1 (en) * | 1985-04-25 | 1989-05-12 | Antonin Holy | 9-(phosponylmethoxyalkyl)adenines and method of their preparation |
-
1988
- 1988-11-28 PL PL1988276046A patent/PL158762B1/pl unknown
- 1988-11-28 NZ NZ227104A patent/NZ227104A/en unknown
- 1988-11-28 IE IE883550A patent/IE883550L/xx unknown
- 1988-11-28 AU AU26311/88A patent/AU617724B2/en not_active Ceased
- 1988-11-28 PL PL1988281367A patent/PL160924B1/pl unknown
- 1988-11-28 DE DE3852008T patent/DE3852008T2/de not_active Expired - Fee Related
- 1988-11-28 ES ES88311252T patent/ES2064361T3/es not_active Expired - Lifetime
- 1988-11-28 EP EP88311252A patent/EP0319228B1/en not_active Expired - Lifetime
- 1988-11-28 PT PT89098A patent/PT89098B/pt not_active IP Right Cessation
- 1988-11-28 IL IL8851888A patent/IL88518A/xx unknown
- 1988-11-28 MA MA21693A patent/MA21450A1/fr unknown
- 1988-11-28 DK DK663588A patent/DK663588A/da not_active Application Discontinuation
- 1988-11-28 MY MYPI88001372A patent/MY103502A/en unknown
- 1988-11-28 PL PL1988281368A patent/PL160927B1/pl unknown
- 1988-11-28 AT AT88311252T patent/ATE113601T1/de not_active IP Right Cessation
- 1988-11-29 PH PH37871A patent/PH26927A/en unknown
- 1988-11-29 FI FI885544A patent/FI885544A/fi not_active Application Discontinuation
- 1988-11-29 JP JP63299785A patent/JPH02293A/ja active Pending
- 1988-11-29 NO NO88885313A patent/NO885313L/no unknown
- 1988-11-30 HU HU886112A patent/HU202244B/hu not_active IP Right Cessation
- 1988-11-30 KR KR1019880016027A patent/KR890008141A/ko not_active Application Discontinuation
-
1995
- 1995-02-01 GR GR940404074T patent/GR3014910T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL281368A1 (en) | 1990-05-28 |
| PL276046A1 (en) | 1990-01-08 |
| EP0319228A2 (en) | 1989-06-07 |
| KR890008141A (ko) | 1989-07-10 |
| PT89098B (pt) | 1993-03-31 |
| HU202244B (en) | 1991-02-28 |
| DE3852008D1 (de) | 1994-12-08 |
| EP0319228A3 (en) | 1990-05-16 |
| AU617724B2 (en) | 1991-12-05 |
| JPH02293A (ja) | 1990-01-05 |
| PH26927A (en) | 1992-12-02 |
| DK663588D0 (da) | 1988-11-28 |
| NO885313D0 (no) | 1988-11-29 |
| PL160927B1 (pl) | 1993-05-31 |
| IE883550L (en) | 1989-05-30 |
| PL158762B1 (en) | 1992-10-30 |
| MY103502A (en) | 1993-06-30 |
| EP0319228B1 (en) | 1994-11-02 |
| FI885544A (fi) | 1989-05-31 |
| PL160924B1 (en) | 1993-05-31 |
| PT89098A (pt) | 1988-12-01 |
| PL281367A1 (en) | 1990-05-28 |
| IL88518A0 (en) | 1989-06-30 |
| NZ227104A (en) | 1991-11-26 |
| MA21450A1 (fr) | 1989-07-01 |
| NO885313L (no) | 1989-05-31 |
| ES2064361T3 (es) | 1995-02-01 |
| DE3852008T2 (de) | 1995-03-23 |
| HUT50352A (en) | 1990-01-29 |
| AU2631188A (en) | 1989-06-15 |
| GR3014910T3 (en) | 1995-05-31 |
| IL88518A (en) | 1994-02-27 |
| FI885544A0 (fi) | 1988-11-29 |
| ATE113601T1 (de) | 1994-11-15 |
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| ES2057016T3 (es) | Compuestos de acido 3-pirrolidiniltio-1-azabiciclo (3.2.0) hept-2-eno-2-carboxilico. | |
| DK663588A (da) | Purinderivater | |
| DK595886A (da) | Guaninderivater | |
| FI904066A0 (fi) | Nya foereningar. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |