PH22387A - Dosage inhalator - Google Patents

Dosage inhalator

Info

Publication number
PH22387A
PH22387A PH27463A PH27463A PH22387A PH 22387 A PH22387 A PH 22387A PH 27463 A PH27463 A PH 27463A PH 27463 A PH27463 A PH 27463A PH 22387 A PH22387 A PH 22387A
Authority
PH
Philippines
Prior art keywords
active compound
membrane
dosing
inhalator
air
Prior art date
Application number
PH27463A
Other languages
English (en)
Inventor
Kjell Ingvar Leopold Wetterlin
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of PH22387A publication Critical patent/PH22387A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Disintegrating Or Milling (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)
  • Nozzles (AREA)
  • Steroid Compounds (AREA)
PH27463A 1981-07-08 1982-06-21 Dosage inhalator PH22387A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8104239 1981-07-08

Publications (1)

Publication Number Publication Date
PH22387A true PH22387A (en) 1988-08-12

Family

ID=20344220

Family Applications (1)

Application Number Title Priority Date Filing Date
PH27463A PH22387A (en) 1981-07-08 1982-06-21 Dosage inhalator

Country Status (30)

Country Link
US (1) US4524769A (enExample)
EP (1) EP0069715B1 (enExample)
JP (1) JPS5819269A (enExample)
KR (1) KR880001811B1 (enExample)
AT (1) ATE23272T1 (enExample)
AU (1) AU559297B2 (enExample)
CA (1) CA1178151A (enExample)
CY (1) CY1492A (enExample)
DE (1) DE3274065D1 (enExample)
DK (1) DK159052C (enExample)
EG (1) EG16516A (enExample)
ES (1) ES276079Y (enExample)
FI (1) FI77375C (enExample)
GR (1) GR76522B (enExample)
HK (1) HK64389A (enExample)
HU (1) HU189154B (enExample)
IE (1) IE53933B1 (enExample)
IL (1) IL66053A (enExample)
IN (1) IN158972B (enExample)
IS (1) IS1268B6 (enExample)
KE (1) KE3890A (enExample)
MY (1) MY100090A (enExample)
NO (1) NO154294C (enExample)
NZ (1) NZ201154A (enExample)
PH (1) PH22387A (enExample)
PL (1) PL132252B1 (enExample)
PT (1) PT75211B (enExample)
SG (1) SG37089G (enExample)
YU (1) YU45115B (enExample)
ZA (1) ZA824264B (enExample)

Families Citing this family (355)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
SE448277B (sv) * 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
SE453566B (sv) * 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
US4929329A (en) * 1987-04-27 1990-05-29 Eg&G, Inc. Electrophoresis cassette system with apparatus and method for filling same
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
GB8909891D0 (en) * 1989-04-28 1989-06-14 Riker Laboratories Inc Device
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5192548A (en) * 1990-04-30 1993-03-09 Riker Laboratoires, Inc. Device
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
DE69121105T2 (de) * 1990-09-12 1996-12-12 Hans Bisgaard Inhaliervorrichtung
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5304125A (en) * 1990-10-05 1994-04-19 The University Of North Carolina Apparatus for administering solid particulate aerosols to the lungs
AU6130594A (en) * 1991-03-05 1994-08-15 Miris Medical Corporation Method and device for correcting the drift offset of a pressure sensor of a flowmeter
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5469750A (en) * 1991-03-05 1995-11-28 Aradigm Corporation Method and apparatus for sensing flow in two directions and automatic calibration thereof
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
WO1992018188A1 (en) * 1991-04-15 1992-10-29 Huhtamäki Oy Device intended for measuring a dose of powdered medicament for inhalation
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
FR2676929B1 (fr) * 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
ATE137675T1 (de) * 1991-06-26 1996-05-15 Schering Corp Inhalator für medikamente in pulverform
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
EP0826386B1 (en) * 1991-08-26 2003-11-26 Minnesota Mining And Manufacturing Company Powder dispenser
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
US5546932A (en) * 1992-03-25 1996-08-20 Tebro Sa Powder jet dispenser for medicament inhalation therapies
SE9201411D0 (sv) * 1992-05-05 1992-05-05 Astra Ab Dosage inhalator with indicating/interupting means
ES2118234T3 (es) * 1992-05-29 1998-09-16 Ggu Gesundheits Umweltforsch Dispositivo para generar particulas inhalables de sustancias activas.
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
KR0177265B1 (ko) * 1992-10-19 1999-04-01 미첼 알. 우드베리 건분말 흡입기
WO1994011044A2 (en) 1992-11-12 1994-05-26 Minnesota Mining And Manufacturing Company Powder inhaler
DE4239402A1 (de) * 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
US6250300B1 (en) 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
DE69323897T2 (de) * 1992-12-18 1999-11-04 Schering Corp., Kenilworth Inhalator für pulverförmige medikamente
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
KR960701672A (ko) * 1993-03-03 1996-03-28 윌리엄 피. 알트만 건조 분말 흡입기의 약제 캐리어(dry powder inhalator medicament carrier)
GB9306703D0 (en) * 1993-03-31 1993-05-26 Fisons Plc Inhalation device
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
TW402506B (en) 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US5830853A (en) * 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
DE4400084C2 (de) * 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
AU124387S (en) * 1994-03-25 1995-08-11 Astra Ab Training device for an inhaler
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
DE4415462C1 (de) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhalator
US6165976A (en) * 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5647347A (en) * 1994-10-21 1997-07-15 Glaxo Wellcome Inc. Medicament carrier for dry powder inhalator
SE9404439D0 (sv) * 1994-12-21 1994-12-21 Astra Ab Inhalation device
NZ298169A (en) 1994-12-22 1999-09-29 Astra Ab Aerosol drug formulation; comprises hydrofluoroalkane propellant, medicament for inhalation and a surfactant
KR100389080B1 (ko) * 1994-12-22 2003-10-17 아스트라제네카 악티에볼라그 부갑상선호르몬(pth)을포함하는흡입용치료제제
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5612053A (en) 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
DE19518810A1 (de) * 1995-05-26 1996-11-28 Bayer Ag Nasal-Applikator
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
GB9626263D0 (en) 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
SE9700937D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
GB9902493D0 (en) 1999-02-05 1999-03-24 Glaxo Group Ltd Inhalation device
GB9905538D0 (en) 1999-03-10 1999-05-05 Glaxo Group Ltd A device
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
ATE289825T1 (de) 1999-04-21 2005-03-15 1355540 Ontario Inc Methacoline oder histamine formulierungen zur feststellung von asthma
ES2241611T3 (es) 1999-06-05 2005-11-01 Innovata Biomed Limited Sisstema de suministro de medicamentos.
AU779986B2 (en) 1999-06-29 2005-02-24 Mannkind Corporation Purification and stabilization of peptide and protein pharmaceutical agents
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
GB9917637D0 (en) * 1999-07-27 1999-09-29 Co Ordinated Drug Dev Improvements in or relating to inhaler devices
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
EP1210067A2 (en) * 1999-08-25 2002-06-05 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
ATE296654T1 (de) * 1999-12-07 2005-06-15 Orion Corp Mehrfachpulverinhalator
US6761909B1 (en) 1999-12-21 2004-07-13 Rxkinetix, Inc. Particulate insulin-containing products and method of manufacture
WO2001045731A1 (en) 1999-12-21 2001-06-28 Rxkinetix, Inc. Particulate drug-containing products and method of manufacture
HUP0300491A2 (en) 2000-02-28 2003-07-28 Vectura Ltd Improvements in or relating to the delivery of oral drugs
CA2382133C (en) * 2000-05-10 2010-11-23 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
CO5310534A1 (es) 2000-08-05 2003-08-29 Glaxo Group Ltd Nuevos derivados de androstano anti-inflamatorios
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
DE10047722A1 (de) * 2000-09-27 2002-04-11 Schuckmann Alfred Von Von Saugluftstrom des Benutzers aktivierbare Dosiervorrichtung
FI20002363A0 (fi) * 2000-10-27 2000-10-27 Orion Yhtymae Oyj Jauheinhalaattori
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
AU2002230993B2 (en) 2000-12-29 2006-02-02 Alkermes, Inc. Particles for inhalation having sustained release properties
ES2291452T3 (es) * 2001-02-06 2008-03-01 Innovata Biomed Limited Formulacion bimodal de polvo seco para inhalacion.
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
ES2296923T3 (es) 2001-03-22 2008-05-01 Glaxo Group Limited Derivados formanilidas como agonistas del adrenorreceptor beta2.
EP1381417A4 (en) * 2001-04-26 2009-12-30 New England Pharm Inc DEVICE FOR RELEASING SATISFIED DOSHES OF LIQUID AND POWDERY MEDIUM
ES2314052T3 (es) 2001-04-30 2009-03-16 Glaxo Group Limited Derivados de ester de 17beta-carbotioato de androstano con un grupo ester ciclico en la posicion 17alfa.
FI20011317A0 (fi) * 2001-06-20 2001-06-20 Orion Corp Jauheinhalaattori
DE10129703A1 (de) 2001-06-22 2003-01-02 Sofotec Gmbh & Co Kg Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
MXPA04002405A (es) 2001-09-14 2004-05-31 Glaxo Group Limetd Derivados de fenetanolamina para tratamiento de enfermedades respiratorias.
EP1487417A4 (en) 2001-09-17 2010-03-17 Glaxo Group Ltd DRY POWDER DRUG FORMULATIONS
WO2003043603A1 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
ES2415654T3 (es) * 2001-11-20 2013-07-26 Civitas Therapeutics, Inc. Composiciones particuladas mejoradas para suministro pulmonar
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
EP1458360B1 (en) * 2001-12-19 2011-05-11 Novartis AG Pulmonary delivery of aminoglycosides
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium
SE524957C2 (sv) 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
SE525027C2 (sv) * 2002-04-12 2004-11-16 Microdrug Ag Anordning utgörande en pulverlufthyvel
US20030196661A1 (en) * 2002-04-19 2003-10-23 Miekka Richard George Power inhaler employing unit doses of powders in pressurized packages
US7271197B2 (en) 2002-04-25 2007-09-18 Glaxo Group Limited Phenethanolamine derivatives
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
DE10300032B3 (de) * 2003-01-03 2004-05-27 E. Braun Gmbh Pulverinhalator
US20040173211A1 (en) * 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
WO2004066912A2 (en) * 2003-01-31 2004-08-12 Technion Research & Development Foundation Ltd. Anti-inflammatory compositions and uses thereof
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
WO2004103364A2 (en) * 2003-05-16 2004-12-02 Arriva Pharmaceuticals, Inc. Treatment of respiratory disease by inhalation of synthetic matrix metalloprotease inhibitors
TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
PE20050250A1 (es) 2003-07-17 2005-04-08 Glaxo Group Ltd Antagonistas de los receptores muscarinicos de la acetilcolina
FI20031158A7 (fi) * 2003-08-15 2005-02-16 Medifiq Healthcare Oy Inhalaattori
JP2007505136A (ja) * 2003-09-10 2007-03-08 マツプ・フアーマシユーテイカルズ・インコーポレーテツド ジヒドロエルゴタミンを肺吸入により体循環に送達するためのエアゾール製剤
SE0302665D0 (sv) * 2003-10-07 2003-10-07 Astrazeneca Ab Novel Process
WO2005037280A1 (en) 2003-10-14 2005-04-28 Glaxo Group Limited Muscarinic acetycholine receptor antagonists
AU2004281167A1 (en) 2003-10-17 2005-04-28 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists field of the invention
WO2005041848A2 (en) * 2003-10-27 2005-05-12 Oriel Therapeutics, Inc. Dry powder drug containment system packages with tabs, inhalers and associated methods
PE20050489A1 (es) 2003-11-04 2005-09-02 Glaxo Group Ltd Antagonistas de receptores de acetilcolina muscarinicos
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
CA2547782A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US7384946B2 (en) 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
US7846973B2 (en) 2004-04-02 2010-12-07 Theravance, Inc. Chemical process and new crystalline form
RU2277940C2 (ru) * 2004-04-16 2006-06-20 Юрий Васильевич Иванов Ингалятор
WO2005102429A1 (en) * 2004-04-21 2005-11-03 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
PE20060259A1 (es) 2004-04-27 2006-03-25 Glaxo Group Ltd Compuestos de quinuclidina como antagonistas del receptor de acetilcolina muscarinico
WO2005112644A2 (en) 2004-05-13 2005-12-01 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
PT1905451E (pt) 2004-05-31 2010-03-31 Almirall Sa Combinações que compreendem agentes antimuscarínicos e corticosteróides
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
BRPI0514293B1 (pt) 2004-08-23 2022-07-19 Mannkind Corporation Sistema microparticulado para distribuição de droga
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
CN101155590A (zh) 2005-02-10 2008-04-02 葛兰素集团有限公司 使用预分选技术制备乳糖的方法以及由此形成的药物制剂
PE20100741A1 (es) 2005-03-25 2010-11-25 Glaxo Group Ltd COMPUESTOS DERIVADOS DE 3,4-DIHIDROPIRIMIDO[4,5-d]PIRIMIDIN-2(1H)-ONA COMO INHIBIDORES DE QUINASA p38
TWI389690B (zh) 2005-03-25 2013-03-21 Glaxo Group Ltd 新穎化合物（一）
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
JP2009504768A (ja) 2005-08-18 2009-02-05 グラクソ グループ リミテッド ムスカリン性アセチルコリン受容体アンタゴニスト
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
DK1928423T3 (en) 2005-09-14 2016-02-29 Mannkind Corp A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
GB2433207B (en) 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
CA2643464C (en) 2006-02-22 2018-09-04 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
AU2007224178B2 (en) * 2006-03-03 2013-03-07 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
GB0605723D0 (en) 2006-03-23 2006-05-03 3M Innovative Properties Co Powder filling processes
WO2007121256A2 (en) 2006-04-12 2007-10-25 Biodel, Inc. Rapid acting and long acting insulin combination formulations
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
PT103481B (pt) * 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
AU2008214205B2 (en) * 2007-02-11 2014-04-24 Map Pharmaceuticals, Inc. Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
PE20081889A1 (es) 2007-03-23 2009-03-05 Smithkline Beecham Corp Indol carboxamidas como inhibidores de ikk2
US20090211576A1 (en) * 2007-10-02 2009-08-27 Timo Lehtonen Safety and abuse deterrent improved device
WO2011163272A1 (en) 2010-06-21 2011-12-29 Mannkind Corporation Dry powder drug delivery system and methods
JP5081771B2 (ja) * 2007-11-09 2012-11-28 日立オートモティブシステムズ株式会社 粉末薬剤投与器
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
EP2096105A1 (en) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
WO2009117151A2 (en) 2008-03-20 2009-09-24 Virun, Inc. Compositions containing non-polar compounds
CN102036572A (zh) 2008-03-20 2011-04-27 维尔恩公司 包含生育酚的peg衍生物的乳剂
SG192447A1 (en) * 2008-03-27 2013-08-30 Mannkind Corp A dry powder inhalation system
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN106039494B (zh) 2008-06-13 2019-12-24 曼金德公司 干粉吸入器和用于药物输送的系统
BRPI0914308B8 (pt) 2008-06-20 2021-06-22 Mannkind Corp sistema de inalação
US8337931B2 (en) * 2008-06-23 2012-12-25 Virun, Inc. Compositions containing non-polar compounds
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CN102405044A (zh) * 2009-02-06 2012-04-04 南加利福尼亚大学 含有单萜的治疗组合物
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
ES2994042T3 (en) 2009-02-26 2025-01-16 Glaxo Group Ltd Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
MY186975A (en) 2009-06-12 2021-08-26 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
CA2764830A1 (en) 2009-06-16 2010-12-23 Schering Corporation Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
PL2453894T3 (pl) 2009-07-15 2016-04-29 Theravance Biopharma R&D Ip Llc Postać krystaliczna wolnej zasady związku bifenylowego
US20110229437A1 (en) * 2009-09-17 2011-09-22 Mutual Pharmaceutical Company, Inc. Method of Treating Asthma with Antiviral Agents
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
US9492625B2 (en) 2009-11-12 2016-11-15 Stc.Unm Dry powder inhaler with flutter dispersion member
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
CN104744215B (zh) 2010-03-03 2019-03-15 尼昂克技术公司 包含单萜的药物组合物
EP2563164B1 (en) 2010-03-23 2016-06-29 Virun, Inc. Nanoemulsion including sucrose fatty acid ester
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
WO2011162802A1 (en) 2010-06-21 2011-12-29 Virun, Inc. Compositions containing non-polar compounds
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
EP3950028B1 (en) 2010-08-23 2024-08-07 Darren Rubin Systems of aerosol delivery with airflow regulation
CN110464718A (zh) 2010-08-27 2019-11-19 尼昂克技术公司 包含poh衍生物的药物组合物
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
WO2012028662A1 (en) 2010-08-31 2012-03-08 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
ES2546422T5 (es) 2010-08-31 2023-01-20 Glaxosmithkline Ip Dev Ltd Productos medicinales de inhalación de polvo seco que presentan propiedades de control de la humedad y procedimientos de administración de los mismos
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
US9297813B2 (en) 2010-11-11 2016-03-29 Agency For Science, Technology And Research Targeting metabolic enzymes in human cancer
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EP2463289A1 (en) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
JP6050758B2 (ja) 2010-12-07 2016-12-21 レスピラ セラピューティクス インコーポレイテッドＲｅｓｐｉｒａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 乾燥粉末吸入器及びその作動方法
EP2651864B1 (en) 2010-12-17 2016-07-13 Neonc Technologies Inc. Methods and devices for using isoperillyl alcohol
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2518070A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors
EP2518071A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridine derivatives as PI3K inhibitors
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2527344A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
EP2554544A1 (en) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1h)-one derivatives as jak inhibitors
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
JP6018640B2 (ja) 2011-10-24 2016-11-02 マンカインド コーポレイション 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム
EP2592077A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
JP2015504051A (ja) 2011-12-30 2015-02-05 グライフォルス・ス・アー 肺の増悪の発現または進行を遅延させるためのアルファ１−プロテイナーゼ阻害剤
US10874122B2 (en) 2012-02-10 2020-12-29 Virun, Inc. Beverage compositions containing non-polar compounds
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2647627A1 (en) 2012-04-02 2013-10-09 Almirall, S.A. Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one.
CN104379559B (zh) 2012-04-27 2016-11-09 葛兰素集团有限公司 化合物
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
EP2666465A1 (en) 2012-05-25 2013-11-27 Almirall, S.A. Novel dosage and formulation
EP2668941A1 (en) 2012-05-31 2013-12-04 Almirall, S.A. Novel dosage form and formulation of abediterol
DK2872205T3 (en) 2012-07-12 2017-02-27 Mannkind Corp DRY POWDER FORMAL ADMINISTRATION SYSTEM
WO2014014650A1 (en) 2012-07-19 2014-01-23 3M Innovative Properties Company Powder feeding apparatus
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015012312A2 (pt) 2012-11-28 2017-07-11 Intercept Pharmaceuticals Inc método de tratamento, redução do risco, prevenção ou alívio de uma afecção ou doença pulmonar em um sujeito; método de redução ou supressão de inflamação no pulmão em um sujeito; e método de promoção de reparo pulmonar em um sujeito
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
BR112015013628A2 (pt) 2012-12-18 2017-07-11 Almirall Sa derivados de carbamato de ciclo-hexila e quinuclidinila tendo atividades agonista adrenérgica de beta2 e antagonista muscarínica de m3
AR094797A1 (es) 2013-02-15 2015-08-26 Almirall Sa Derivados de pirrolotriazina como inhibidores de pi3k
KR102391750B1 (ko) 2013-03-15 2022-04-28 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
EP3021834A1 (en) 2013-07-18 2016-05-25 MannKind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
WO2015091285A1 (en) 2013-12-19 2015-06-25 Almirall S.A. Dosage formulation comprising salmeterol and fluticasone propionate
EP3107606B1 (en) 2014-02-21 2024-08-28 David Brown Inhalation device for inhaling powders
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US20170100385A1 (en) 2014-05-12 2017-04-13 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions comprising danirixin for treating infectious diseases
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3838317A1 (en) 2015-01-14 2021-06-23 Respira Therapeutics, Inc. Dry powder inhaler
CN107613768B (zh) 2015-02-12 2020-10-20 NeOnc技术股份有限公司 包含紫苏醇衍生物的药物组合物
CN107428828A (zh) 2015-03-11 2017-12-01 葛兰素史密斯克莱知识产权发展有限公司 Tslp结合蛋白
EP3286178A1 (en) 2015-04-21 2018-02-28 Almirall S.A. Amino-substituted heterocyclic derivatives as sodium channel inhibitors
EP3294390B1 (en) 2015-05-08 2022-10-05 Iconovo AB Dry powder inhaler
US10604509B2 (en) 2015-06-15 2020-03-31 Glaxosmithkline Intellectual Property Development Limited Nrf2 regulators
ES2834490T3 (es) 2015-06-15 2021-06-17 Glaxosmithkline Ip Dev Ltd Reguladores de NRF2
US20180179167A1 (en) 2015-06-15 2018-06-28 Glaxosmithkline Intellectual Property Development Limited Nrf2 REGULATORS
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
US10364256B2 (en) 2015-10-06 2019-07-30 Glaxosmithkline Intellectual Property Development Limited Biaryl pyrazoles as NRF2 regulators
EP3371167A1 (en) 2015-10-06 2018-09-12 GlaxoSmithKline Intellectual Property Development Limited Arylcyclohexyl pyrazoles as nrf2 regulators
WO2017076990A1 (en) 2015-11-05 2017-05-11 Almirall, S.A. Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
ES2877763T3 (es) 2016-09-20 2021-11-17 Glaxosmithkline Ip No 2 Ltd Antagonistas del trpv4
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產（第二）有限公司 Ｔｒｐｖ４拮抗劑
JP7144411B2 (ja) 2016-11-30 2022-09-29 ネオンク テクノロジーズ インク． ペリリルアルコール－３－ブロモピルベート複合体及びがんの治療方法
WO2018104766A1 (en) 2016-12-06 2018-06-14 Glaxosmithkline Intellectual Property Development Limited 3-(2,3-dihydro-1h-inden-5-yl)propanoic acid derivatives and their use as nrf2 regulators
WO2018109641A1 (en) 2016-12-12 2018-06-21 Glaxosmithkline Intellectual Property Development Limited 3-carboxylic acid pyrroles as nrf2 regulators
EP3551621A1 (en) 2016-12-12 2019-10-16 GlaxoSmithKline Intellectual Property Development Limited N-aryl pyrazoles as nrf2 regulators
US20220002272A1 (en) 2016-12-14 2022-01-06 Glaxosmithkline Intellectual Property Development Limited Bisaryl lactams as nrf2 activators
WO2018109647A1 (en) 2016-12-14 2018-06-21 Glaxosmithkline Intellectual Property Development Limited Bisaryl amides as nrf2 regulators
EP3555078B1 (en) 2016-12-14 2024-03-27 GlaxoSmithKline Intellectual Property Development Limited Bisaryl heterocycles as nrf2 activators
US11059816B2 (en) 2016-12-15 2021-07-13 Glaxosmithkline Intellectual Property Development Limited Ether linked triazoles as NRF2 activators
KR20190091455A (ko) 2016-12-15 2019-08-06 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Nrf2 화합물
WO2018174938A1 (en) 2017-03-23 2018-09-27 Virun, Inc. Stable dry powders and emulsions containing probiotics and mucoadhesive protein
TWI778052B (zh) 2017-04-24 2022-09-21 美商共結晶製藥公司 流感病毒複製之抑制劑
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
EP3687608B1 (en) * 2017-09-28 2025-06-18 Iconovo AB Dry powder inhaler with means for enhancing dispersion
WO2019116231A1 (en) 2017-12-11 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
US20210177861A1 (en) 2017-12-11 2021-06-17 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
GB201720989D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
TWI795510B (zh) 2018-01-17 2023-03-11 英商葛蘭素史密斯克藍智慧財產發展有限公司 PI4KIIIβ抑制劑
EP3749291B1 (en) 2018-02-08 2024-01-03 University of Southern California Methods of permeabilizing the blood brain barrier
US11643407B2 (en) 2018-05-23 2023-05-09 Glaxosmithkline Intellectual Property Development Limited Indanes as NRF2 activators
EP3829719B1 (en) 2018-07-27 2025-04-02 Cocrystal Pharma, Inc. Pyrrolo[2,3-b]pyridin derivatives as inhibitors of influenza virus replication
TWI844564B (zh) 2018-09-10 2024-06-11 美商共結晶製藥公司 流感病毒複製之抑制劑
KR102620705B1 (ko) 2018-10-11 2024-01-04 삼성전자주식회사 전자 장치 및 그의 동작 방법
AU2019361038B2 (en) 2018-10-17 2025-07-03 Cocrystal Pharma, Inc. Combinations of inhibitors of influenza virus replication
US12156876B2 (en) 2018-11-13 2024-12-03 Cocrystal Pharma, Inc. Formulations of influenza therapeutics
EP3887355A1 (en) 2018-11-26 2021-10-06 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
EP3924023A1 (en) * 2019-02-15 2021-12-22 Iconovo AB Inhaler
AU2020235261A1 (en) 2019-03-14 2021-09-16 Om Pharma Sa Process for making stable bacterial extracts and their use as pharmaceuticals
MX2021010908A (es) 2019-03-14 2021-10-01 Om Pharma Sa Metodo para tratar y/o prevenir asma, exacerbaciones de asma, asma alergica y/o condiciones asociadas con microbiota relacionada con trastornos respiratorios.
GB201908536D0 (en) 2019-06-13 2019-07-31 Glaxosmithkline Ip Dev Ltd Compounds
US20230151034A1 (en) 2020-03-17 2023-05-18 Cocrystal Pharma, Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
CN115698035A (zh) 2020-04-10 2023-02-03 共晶制药公司 诺如病毒及冠状病毒复制的抑制剂
EP4138884A1 (en) 2020-04-20 2023-03-01 Sorrento Therapeutics, Inc. Pulmonary administration of ace2 polypeptides
WO2022175425A1 (en) 2021-02-22 2022-08-25 Glaxosmithkline Intellectual Property Development Limited Inhaled mtor kinase inhibitors for use in the treatment or the prevention of a respiratory rna virus infection
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
US20240398757A1 (en) 2021-08-03 2024-12-05 Cocrystal Pharma, Inc. Inhibitors for coronaviruses
JP2025513460A (ja) 2022-04-22 2025-04-24 クエンチ メディカル インコーポレイテッド 粉末吸入による医薬品の送達
WO2023232976A1 (en) 2022-06-03 2023-12-07 Ags Therapeutics Sas Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11485A (en) * 1854-08-08 Befbigeeatob fobj maeine ejstgiites
US2641254A (en) * 1948-10-18 1953-06-09 Frederick M Turnbull Applicator
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2573918A (en) * 1949-11-05 1951-11-06 Vick Chemical Company Device for dispensing medicaments
US2581182A (en) * 1950-03-14 1952-01-01 Abbott Lab Inhaler
DE1813993C3 (de) * 1968-12-11 1974-01-24 Paul Ritzau Pari-Werk Kg, 8135 Soecking Vorrichtung zum Zerstäuben und Vernebeln von flüssigen oder pulverförmigen Stoffen
US3653380A (en) * 1970-02-16 1972-04-04 American Cyanamid Co Aerosol powder dosage dispensing device
US4003500A (en) * 1970-12-31 1977-01-18 Hoechst Aktiengesellschaft Metering device
US3831606A (en) * 1971-02-19 1974-08-27 Alza Corp Auto inhaler
DE2502251A1 (de) * 1975-01-17 1976-07-22 Schering Ag Vorrichtung zur inhalation pulverfoermiger feststoffe
SU651766A1 (ru) * 1975-11-25 1979-03-15 Литовский Научно-Исследовательский Институт Ветеринарии Электроаэрозольный аппарат дл вакцинации животных
SU570775A1 (ru) * 1976-02-02 1977-08-30 Институт Теоретических Проблем Химической Технологии Ан Азербайджанской Сср Объемный микродозатор жидкости
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2716323C2 (de) * 1977-04-07 1986-03-13 Schering AG, 1000 Berlin und 4709 Bergkamen Vorrichtung zur Inhalation von Arzneimitteln
DE2807866C2 (de) * 1978-02-23 1979-09-20 Plasmainvent Ag, Zug (Schweiz) Vorrichtung zum dosierten Zuführen von Pulver zu einer Pulververarbeitungseinheit
DE2837040C2 (de) * 1978-08-24 1982-10-21 Siemens AG, 1000 Berlin und 8000 München Flüssigkeitstransportsystem für ein Inhalationsgerät
SU799766A1 (ru) * 1979-01-18 1981-01-30 Московский Научно-Исследовательс-Кий Институт Вакцин И Сывороток Им.И.И.Мечникова Устройство дл распылени порош-КООбРАзНыХ ВЕщЕСТВ
IT7920688U1 (it) * 1979-02-05 1980-08-05 Chiesi Paolo Inalatore per sostanze medicamentose pulverulente, con combinata funzione di dosatore
US4253591A (en) * 1979-06-18 1981-03-03 General Electric Company Mercury doser
US4262666A (en) * 1979-10-24 1981-04-21 Nelson Byron G Inhalator-breathing apparatus

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YU45115B (en) 1992-03-10
HU189154B (en) 1986-06-30
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ATE23272T1 (de) 1986-11-15
JPH0147190B2 (enExample) 1989-10-12
FI77375C (fi) 1989-03-10
ES276079Y (es) 1984-12-16
PT75211A (en) 1982-08-01
NO154294B (no) 1986-05-20
YU141482A (en) 1987-04-30
DK304482A (da) 1983-01-09
KR840000250A (ko) 1984-02-18
NO822370L (no) 1983-01-10
IS2734A7 (is) 1983-01-09
EP0069715B1 (en) 1986-11-05
MY100090A (en) 1989-08-18
KR880001811B1 (ko) 1988-09-19
IN158972B (enExample) 1987-02-28
ZA824264B (en) 1983-04-27
KE3890A (en) 1989-09-01
NO154294C (no) 1986-09-03
FI77375B (fi) 1988-11-30
EG16516A (en) 1992-06-30
PL132252B1 (en) 1985-02-28
SG37089G (en) 1989-10-13
DK159052B (da) 1990-08-27
US4524769A (en) 1985-06-25
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IS1268B6 (is) 1987-05-27
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IL66053A (en) 1987-10-30
AU559297B2 (en) 1987-03-05
ES276079U (es) 1984-05-01
HK64389A (en) 1989-08-18
EP0069715A1 (en) 1983-01-12
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FI822423A0 (fi) 1982-07-07
CA1178151A (en) 1984-11-20
JPS5819269A (ja) 1983-02-04
PT75211B (en) 1985-11-12
AU8560882A (en) 1983-01-13
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DE3274065D1 (de) 1986-12-11
FI822423L (fi) 1983-01-09

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