ATE79284T1 - Zur vollstaendigen entleerung der kapsel geeigneter inhalator. - Google Patents

Zur vollstaendigen entleerung der kapsel geeigneter inhalator.

Info

Publication number
ATE79284T1
ATE79284T1 AT90102555T AT90102555T ATE79284T1 AT E79284 T1 ATE79284 T1 AT E79284T1 AT 90102555 T AT90102555 T AT 90102555T AT 90102555 T AT90102555 T AT 90102555T AT E79284 T1 ATE79284 T1 AT E79284T1
Authority
AT
Austria
Prior art keywords
capsule
complete emptying
chamber
discharge holes
inhaler suitable
Prior art date
Application number
AT90102555T
Other languages
English (en)
Inventor
Luigi Valentini
Giancarlo Ceschel
Original Assignee
Phidea Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phidea Spa filed Critical Phidea Spa
Application granted granted Critical
Publication of ATE79284T1 publication Critical patent/ATE79284T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
AT90102555T 1989-02-23 1990-02-09 Zur vollstaendigen entleerung der kapsel geeigneter inhalator. ATE79284T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8919539A IT1228459B (it) 1989-02-23 1989-02-23 Inalatore con svuotamento regolare e completo della capsula.

Publications (1)

Publication Number Publication Date
ATE79284T1 true ATE79284T1 (de) 1992-08-15

Family

ID=11158882

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90102555T ATE79284T1 (de) 1989-02-23 1990-02-09 Zur vollstaendigen entleerung der kapsel geeigneter inhalator.

Country Status (7)

Country Link
US (1) US4995385A (de)
EP (1) EP0388621B1 (de)
AT (1) ATE79284T1 (de)
DE (1) DE69000249T2 (de)
DK (1) DK0388621T3 (de)
ES (1) ES2034781T3 (de)
IT (1) IT1228459B (de)

Families Citing this family (239)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
EP0940154B1 (de) * 1991-07-02 2007-04-18 Nektar Therapeutics Abgabevorrichtung für nebelförmige Medikamente
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
GB9216038D0 (en) * 1992-07-28 1992-09-09 Bespak Plc Dispensing apparatus for powdered medicaments
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
ES2218543T3 (es) * 1994-03-07 2004-11-16 Nektar Therapeutics Procedimiento y preparacion para la administracion de insulina por via pulmonar.
JP3372105B2 (ja) * 1994-05-26 2003-01-27 株式会社日立ユニシアオートモティブ 吸入式投薬器
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
JP3388896B2 (ja) * 1994-08-08 2003-03-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
JP3706136B2 (ja) * 1994-09-21 2005-10-12 ネクター セラピューティクス 乾燥粉末薬剤の分散装置及び方法
US5901703A (en) * 1995-02-06 1999-05-11 Unisia Jecs Corporation Medicine administering device for nasal cavities
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
AUPN976496A0 (en) * 1996-05-10 1996-05-30 Glaxo Wellcome Australia Ltd Unit dose dispensing device
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
PT898978E (pt) * 1997-01-30 2005-07-29 Dott Ltd Co Aplicador de medicamentos por inalacao
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US20020017295A1 (en) * 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
GB9820746D0 (en) † 1998-09-23 1998-11-18 Pharmax Limited Micronised pharmaceutical compositions
US6858199B1 (en) 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1649886B1 (de) * 1999-07-23 2008-04-02 MannKind Corporation Einzelportionskapseln für einen Trockenpulverinhalator
AU2005201843B2 (en) * 1999-07-23 2009-01-29 Mannkind Corporation Unit dose capsules and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US6586008B1 (en) * 1999-08-25 2003-07-01 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles during spray drying
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
EP1210067A2 (de) * 1999-08-25 2002-06-05 Advanced Inhalation Research, Inc. Modulation der freigabe aus trockenpulverformulierungen
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7252840B1 (en) 1999-08-25 2007-08-07 Advanced Inhalation Research, Inc. Use of simple amino acids to form porous particles
US6810872B1 (en) * 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
US8404217B2 (en) * 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
ES2525087T5 (es) * 2000-05-10 2018-06-28 Novartis Ag Polvos basados en fosfolípidos para administración de fármacos
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
WO2002009674A2 (en) * 2000-07-28 2002-02-07 Inhale Therapeutic Systems, Inc. Methods and compositions to upregulate, redirect or limit immune responses to bioactive compounds
AU2001283546A1 (en) 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
US6613308B2 (en) 2000-09-19 2003-09-02 Advanced Inhalation Research, Inc. Pulmonary delivery in treating disorders of the central nervous system
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
ATE255929T1 (de) 2001-03-05 2003-12-15 Ivo Pera Inhalationsvorrichtung zum dispergieren von in kapseln enthaltenen pulverförmigen medikamente durch den respirationstrakt
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
US7025058B2 (en) 2001-04-26 2006-04-11 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
PL369425A1 (en) * 2001-06-11 2005-04-18 Warner-Lambert Company Llc Breath protection microcapsules
GB2380410B (en) * 2001-10-05 2003-11-19 Alchemy Healthcare Ltd Apparatus for the nasal or oral delivery of a medicament
US20040208832A1 (en) * 2001-11-02 2004-10-21 Bates Michael Timothy Color-coded therapy unit
WO2003041777A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization device with improved endpiece connection
WO2003041776A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization apparatus comprising connectable body and endpiece
ES2415654T3 (es) * 2001-11-20 2013-07-26 Civitas Therapeutics, Inc. Composiciones particuladas mejoradas para suministro pulmonar
US20030129250A1 (en) * 2001-11-20 2003-07-10 Advanced Inhalation Research Inc. Particulate compositions for improving solubility of poorly soluble agents
US20030099601A1 (en) * 2001-11-27 2003-05-29 Gordon Marc S. Inhalation lung surfactant therapy
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
WO2003057593A1 (en) 2001-12-21 2003-07-17 Nektar Therapeutics Capsule package with moisture barrier
JP2005514273A (ja) * 2001-12-21 2005-05-19 ネクター セラピューティクス 包装における医薬製剤の密封
ITMI20020078A1 (it) 2002-01-16 2003-07-16 Fabrizio Niccolai Dispositivo utilizzabile nel tratamento di affezzioni delle vie respiratorie
WO2003079885A2 (en) 2002-03-20 2003-10-02 Advanced Inhalation Research, Inc. Inhalable sustained therapeutic formulations
HUE031167T2 (hu) 2002-03-20 2017-07-28 Civitas Therapeutics Inc A levodopa pulmonális bejuttatása
CA2478801A1 (en) * 2002-03-20 2003-10-02 Advanced Inhalation Research, Inc. Method for administration of growth hormone via pulmonary delivery
US20050163725A1 (en) * 2002-03-20 2005-07-28 Blizzard Charles D. Method for administration of growth hormone via pulmonary delivery
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
US7008644B2 (en) * 2002-03-20 2006-03-07 Advanced Inhalation Research, Inc. Method and apparatus for producing dry particles
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
MXPA04010990A (es) * 2002-05-07 2005-02-14 Nektar Therapeutics Capsulas para inhaladores de polvo seco y metodo s para elaborarlas y utilizarlas.
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
AU2003280102B2 (en) 2002-06-28 2007-01-25 Alkermes, Inc. Inhalable epinephrine
US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
US20050236296A1 (en) * 2002-12-30 2005-10-27 Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) Carry case for aerosolization apparatus
JP2006513235A (ja) * 2002-12-31 2006-04-20 ネクター セラピューティクス 真菌感染症療法のためのエアゾール化可能な医薬製剤
US7669596B2 (en) * 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
US20050056280A1 (en) * 2002-12-31 2005-03-17 Nektar Therapeutics Receptacle for an aerosolizable pharmaceutical formulation
CA2520265C (en) 2003-04-09 2015-02-17 Nektar Therapeutics Aerosolization apparatus with capsule puncture alignment guide
US8869794B1 (en) * 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
SI1610850T2 (sl) * 2003-04-09 2020-11-30 Novartis Ag Naprava za aerosolizacijo s ščitom za vstopni zrak
EP1635786A2 (de) * 2003-05-28 2006-03-22 Nektar Therapeutics Sprühtrocknung einer alkoholischen wässrigen lösung zur herstellung eines wasserunlöslichen wirkstoff-mikroteilchens mit einem teilweisen oder kompletten aminosäure- und/oder phospholipid-überzug
ES2872350T3 (es) 2003-06-13 2021-11-02 Civitas Therapeutics Inc Polvos farmacéuticos de dosis baja para inhalación
US20050214224A1 (en) * 2003-11-04 2005-09-29 Nektar Therapeutics Lipid formulations for spontaneous drug encapsulation
JP2007522149A (ja) * 2004-02-10 2007-08-09 アドバンスト インハレーション リサーチ，インコーポレイテッド 高速放出特性を有する吸入のための粒子
CA2563365A1 (en) * 2004-04-23 2005-11-03 Mystic Pharmaceuticals, Inc. Multiple unit dose drug delivery system
AU2005244128B2 (en) * 2004-05-07 2009-06-25 President And Fellows Of Harvard College Pulmonary malarial vaccine
KR20070026604A (ko) 2004-06-18 2007-03-08 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 기관지 감염의 치료 방법
US8513204B2 (en) * 2004-06-21 2013-08-20 Novartis Ag Compositions comprising amphotericin B, mehods and systems
CA2567785A1 (en) * 2004-06-21 2006-01-05 Nektar Therapeutics Composition comprising amphotericin b methods and systems
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2322180B1 (de) 2004-08-23 2015-05-27 MannKind Corporation Diketopiperazinsalze zur Arzneimitteldarreichung
EP1809252A2 (de) * 2004-10-29 2007-07-25 Presidents and Fellows of Harvard College Partikel zu behandlung von lungeninfektion
MX2007014531A (es) 2005-05-18 2008-04-29 Nektar Therapeutics Valvulas, dispositivos y metodos para terapia endobronquial.
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
RU2390325C2 (ru) 2005-09-14 2010-05-27 Маннкайнд Корпорейшн Способ приготовления лекарственного препарата, основанный на увеличении сродства активных агентов к поверхностям кристаллических микрочастиц
EP1928525A2 (de) * 2005-09-29 2008-06-11 Nektar Therapeutics Aufnahmebehälter und kits, beispielsweise für trockenpulver-verpackungen
US20070123449A1 (en) * 2005-11-01 2007-05-31 Advanced Inhalation Research, Inc. High load particles for inhalation having rapid release properties
GB0524194D0 (en) * 2005-11-28 2006-01-04 Univ Aston Respirable powders
RU2403059C2 (ru) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент
DE102006016903A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
EP2035068A1 (de) * 2006-06-27 2009-03-18 Brin Tech International Limited Inhalator
US20080063722A1 (en) * 2006-09-08 2008-03-13 Advanced Inhalation Research, Inc. Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
EP2668970B1 (de) * 2006-10-25 2016-07-06 Novartis AG Pulverdispersionsvorrichtung
BRPI0806474A2 (pt) * 2007-01-09 2011-09-27 Mystic Pharmaceuticals Inc dispositivos de cartucho intranasal
GB0700839D0 (en) * 2007-01-17 2007-02-21 Braithwaite Philip Device
WO2008144439A1 (en) 2007-05-16 2008-11-27 Mystic Pharmaceuticals, Inc. Combination unit dose dispensing containers
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
US8683995B2 (en) 2007-05-16 2014-04-01 Mystic Pharmaceuticals, Inc. Dose dispensing containers
US8496002B2 (en) * 2007-06-12 2013-07-30 Civitas Therapeutics, Inc. Powder inhaler devices
DE102007040366A1 (de) * 2007-08-17 2009-02-19 Aha Kunststofftechnik Gmbh Trockenpulver-Inhalator
CN101380496A (zh) * 2007-09-03 2009-03-11 东鸿远东有限公司 吸入器
CA2699634C (en) * 2007-09-14 2015-06-09 Mystic Pharmaceuticals, Inc. Deep draw container forming method
RU2517140C2 (ru) * 2007-10-25 2014-05-27 Новартис Аг Способ обработки упаковки с однократной дозой лекартвенного препарата
RU2487730C2 (ru) * 2007-12-05 2013-07-20 Новартис Аг Емкость для лекарственного средства аэрозольного применения
ES2648196T3 (es) 2008-02-07 2017-12-29 The University Of Washington Dispositivo aerosol circunferencial
DE102008014025A1 (de) * 2008-03-13 2009-09-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Sieb für einen Inhalator
KR101621986B1 (ko) 2008-05-15 2016-05-17 노파르티스 아게 플루오로퀴놀론의 폐 전달
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US8636001B2 (en) 2008-06-13 2014-01-28 Mannkind Corporation Dry powder inhaler and system for drug delivery
DK2609954T3 (da) 2008-06-20 2022-02-14 Mannkind Corp Interaktivt apparat til realtidsafbildning af inhalationspræstationer
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (de) 2009-03-11 2013-11-06 MannKind Corporation Gerät, system und verfahren zur messung von widerstand in einem inhaliergerät
US8974828B2 (en) 2009-03-18 2015-03-10 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
EP3184099A1 (de) 2009-03-26 2017-06-28 Pulmatrix, Inc. Trockenpulverformulierungen und verfahren zur behandlung von lungenerkrankungen
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
EP2496295A1 (de) 2009-11-03 2012-09-12 MannKind Corporation Vorrichtung und verfahren zur simulation von einatmungsanstrengungen
JP5415341B2 (ja) * 2010-03-31 2014-02-12 株式会社吉野工業所 粉体吸入デバイス
EP2582421A1 (de) 2010-06-21 2013-04-24 MannKind Corporation System und verfahren zur verabreichung von arzneimitteln in trockenpulverform
DK2585467T3 (en) 2010-06-24 2016-06-13 Gilead Sciences Inc PYRAZOLO [1,5-A] PYRIMIDINES AND TRIAZINES AS ANTIVIRAL AGENTS
ME01924B (me) 2010-07-22 2015-05-20 Gilead Sciences Inc Metode i jedinjenja za lečenje infekcija izazvanih Paramyxoviridae virusom
WO2012030645A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
TW201305185A (zh) 2010-09-13 2013-02-01 Gilead Sciences Inc 用於抗病毒治療之２’－氟取代之碳－核苷類似物
US9642798B2 (en) 2010-09-29 2017-05-09 Pulmatrix, Inc. Monovalent metal cation dry powders for inhalation
US9433576B2 (en) 2010-09-29 2016-09-06 Pulmatrix, Inc. Cationic dry powders
AT510585B1 (de) 2010-11-18 2012-05-15 Apeptico Forschung & Entwicklung Gmbh Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase
EP4088769A1 (de) 2011-03-03 2022-11-16 Impel Pharmaceuticals Inc. Vorrichtung für nasale arzneimittelabgabe
WO2012135765A2 (en) 2011-04-01 2012-10-04 Mannkind Corporation Blister package for pharmaceutical cartridges
EP3851142A1 (de) 2011-05-09 2021-07-21 Impel NeuroPharma Inc. Düsen für nasale arzneimittelabgabe
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN103945859A (zh) 2011-10-24 2014-07-23 曼金德公司 用于治疗疼痛的方法和组合物
US8327610B1 (en) * 2011-12-16 2012-12-11 JCDS Holdings, LLC Capsule opener and emptier
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
US10682476B2 (en) 2012-02-21 2020-06-16 Respira Therapeutics, Inc. Powder inhaler, system and methods
CN104487075A (zh) 2012-02-29 2015-04-01 普马特里克斯公司 可吸入干粉剂
PT2834258T (pt) * 2012-03-13 2017-04-07 Gilead Sciences Inc Análogos de carba-nucleósido 2¿- substituído para tratamento antiviral
KR102102283B1 (ko) 2012-04-17 2020-04-21 길리애드 사이언시즈, 인코포레이티드 항바이러스 치료를 위한 화합물 및 방법
EP2679239A1 (de) 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
US9802012B2 (en) 2012-07-12 2017-10-31 Mannkind Corporation Dry powder drug delivery system and methods
EP2708219A1 (de) * 2012-09-12 2014-03-19 PARI Pharma GmbH Öffnungselement zum Öffnen einer Ampulle in einer Aerosolerzeugungsvorrichtung und Aerosolerzeugungsvorrichtung mit dem Öffnungselement
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757395B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
SG11201507564PA (en) 2013-03-15 2015-10-29 Mannkind Corp Microcrystalline diketopiperazine compositions and methods
JP6473738B2 (ja) 2013-04-01 2019-02-20 パルマトリックス，インコーポレイテッド チオトロピウム乾燥粉末
WO2014179228A1 (en) 2013-04-28 2014-11-06 Impel Neuropharma Inc. Medical unit dose container
CA2910766C (en) 2013-04-30 2020-12-15 Otitopic Inc. Dry powder formulations and methods of use
MX2020009878A (es) 2013-07-18 2022-07-27 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos.
EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
UA119050C2 (uk) 2013-11-11 2019-04-25 Ґілеад Саєнсиз, Інк. ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
US9272123B2 (en) * 2013-12-16 2016-03-01 Esther Gallant Device and method for inserting lubricating capsule
PL3107548T3 (pl) 2014-02-20 2022-10-31 Otitopic Inc. Suche formulacje w proszku do inhalacji
USD752204S1 (en) 2014-03-10 2016-03-22 Civitas Therapeutics, Inc. Indicator for an inhaler
USD755367S1 (en) 2014-03-10 2016-05-03 Civitas Therapeutics, Inc. Indicator for an inhaler
USD752734S1 (en) 2014-03-10 2016-03-29 Civitas Therapeutics, Inc. Inhaler grip
ES2665180T3 (es) 2014-03-18 2018-04-24 Apeptico Forschung Und Entwicklung Gmbh Medicamento de péptido en forma de polvo seco
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
TWI678369B (zh) 2014-07-28 2019-12-01 美商基利科學股份有限公司 用於治療呼吸道合胞病毒感染之噻吩並［３,２-ｄ］嘧啶、呋喃並［３,２-ｄ］嘧啶及吡咯並［３,２-ｄ］嘧啶化合物類
CN116687887A (zh) 2014-07-31 2023-09-05 维克图拉公司 用于吸入的干粉制剂
DE102014215064A1 (de) 2014-07-31 2016-02-04 Pari GmbH Spezialisten für effektive Inhalation Vernebler
TWI673283B (zh) 2014-08-21 2019-10-01 美商基利科學股份有限公司 ２’－氯胺基嘧啶酮及嘧啶二酮核苷類
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3244952A4 (de) * 2015-01-14 2018-11-14 Respira Therapeutics, Inc. Pulverdispersionsverfahren und -vorrichtungen
DE102015108931B3 (de) * 2015-06-05 2016-06-09 Gerresheimer Regensburg Gmbh Gitterelement für einen Inhalator
IL257845B (en) 2015-09-10 2022-07-01 Impel Neuropharma Inc Lined nasal delivery device
MX2018007510A (es) * 2015-12-24 2018-08-01 Philip Morris Products Sa Sistema de suministro de polvo de nicotina.
BR112018010830B1 (pt) 2015-12-24 2023-04-11 Philip Morris Products S.A. Cápsula de partícula de nicotina
EP3411030A4 (de) 2016-02-01 2019-09-04 InCarda Therapeutics, Inc. Elektronische überwachung mit inhalierter pharmakologischer therapie für das management von herzarrhythmien mit vorhofflimmern
WO2017223502A1 (en) 2016-06-24 2017-12-28 Civitas Therapeutics, Inc. Surfactant formulations for inhalation
AU2017341815B2 (en) 2016-10-14 2023-06-15 Pulmatrix Operating Company, Inc. Antifungal dry powders
CA3037824A1 (en) * 2016-11-30 2018-06-07 Gerard Zuber Inhaler with sized cavity
MX2019005889A (es) * 2016-11-30 2019-08-14 Philip Morris Products Sa Inhalador con tapon de extremo de remolinos.
WO2018195086A1 (en) * 2017-04-17 2018-10-25 Respira Therapeutics, Inc. Powder dispersion devices and methods
KR20200003199A (ko) 2017-05-10 2020-01-08 인카다 테라퓨틱스, 인크. 폐 투여에 의해 심장 병태를 치료하기 위한 단위 용량, 에어로졸, 키트 및 방법
CA3062567A1 (en) 2017-05-22 2018-11-29 Insmed Incorporated Glycopeptide derivative compounds and uses thereof
CN115919780A (zh) 2017-09-22 2023-04-07 维克图拉公司 含有硬脂酸镁的干粉组合物
US10786456B2 (en) 2017-09-22 2020-09-29 Otitopic Inc. Inhaled aspirin and magnesium to treat inflammation
CN111163651A (zh) * 2017-10-25 2020-05-15 菲利普莫里斯生产公司 具有边界元件的吸入器
US11571532B2 (en) 2017-11-21 2023-02-07 Impel Pharmaceuticals Inc. Intranasal device with dip tube
WO2019104192A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
BR112020010021A2 (pt) * 2017-12-28 2020-11-03 Philip Morris Products S.A. inalador com túnel de vórtice
EP3735223A4 (de) 2018-01-05 2021-10-13 Impel Neuropharma Inc. Intranasale verabreichung von olanzapin durch olfaktorische präzisionsvorrichtung
ES2937440T3 (es) 2018-01-05 2023-03-28 Impel Pharmaceuticals Inc Administración intranasal de dihidroergotamina mediante un dispositivo olfativo de precisión
EP3517117A1 (de) 2018-01-30 2019-07-31 Medizinische Universität Wien Arzneimittel zur vorbeugung oder behandlung von rhinovirusinfektionen
US10744087B2 (en) 2018-03-22 2020-08-18 Incarda Therapeutics, Inc. Method to slow ventricular rate
EP3772252B1 (de) * 2018-03-26 2022-05-04 Philip Morris Products S.A. Inhalator mit einem durchlöcherten porösen trägerelement
EP3781125A1 (de) 2018-04-18 2021-02-24 Pulmatrix Operating Company, Inc. Antimykotische formulierungen zur pulmonalen verabreichung mit itraconazol
AU2019256453A1 (en) 2018-04-18 2020-11-12 Cipla Technologies LLC Methods of treating fungal infections
KR20210034047A (ko) 2018-07-19 2021-03-29 임펠 뉴로파마 인코포레이티드 파킨슨 병 치료를 위한 레보도파 및 도파 데카르복실라아제 저해제의 기도 전달
US20220023282A1 (en) 2018-12-13 2022-01-27 Mannkind Corporation Compositions of Bedaquiline, Combinations Comprising Them, Processes for Their Preparation, Uses and Methods of Treatment Comprising Them
CA3125430A1 (en) 2019-01-03 2020-07-09 Impel Neuropharma, Inc. Nasal drug delivery device
WO2020180751A1 (en) 2019-03-01 2020-09-10 Flagship Pioneering Innovations Vi, Llc Compositions, methods, and kits for delivery of polyribonucleotides
KR20220010011A (ko) 2019-05-17 2022-01-25 임펠 뉴로파마 인코포레이티드 일회용 비강 전달 장치
WO2020239696A1 (en) 2019-05-24 2020-12-03 Stichting Katholieke Universiteit Improved administration of glycylcyclines by inhalation
EP3760203A1 (de) 2019-07-03 2021-01-06 Medizinische Universität Graz Medikament zur vorbeugung oder behandlung einer stoffwechselstörung
US11007185B2 (en) 2019-08-01 2021-05-18 Incarda Therapeutics, Inc. Antiarrhythmic formulation
CN114599416B (zh) * 2019-11-08 2023-12-22 菲利普莫里斯生产公司 双重激活预防
KR20220131918A (ko) 2019-12-24 2022-09-29 카나 바이오사이언스, 인코포레이션 다이아실글리세롤 키나제 조절 화합물
TWI791193B (zh) 2020-02-18 2023-02-01 美商基利科學股份有限公司 抗病毒化合物
WO2021168004A1 (en) 2020-02-18 2021-08-26 Gilead Sciences, Inc. Antiviral compounds
TW202322824A (zh) 2020-02-18 2023-06-16 美商基利科學股份有限公司 抗病毒化合物
TW202245800A (zh) 2020-02-18 2022-12-01 美商基利科學股份有限公司 抗病毒化合物
US20230039553A1 (en) 2020-05-01 2023-02-09 Gilead Sciences, Inc. Cd73 compounds
EP4051307B1 (de) 2020-05-08 2023-02-01 APEPTICO Forschung und Entwicklung GmbH Peptid zur vorbeugung oder behandlung von covid-19
TW202228792A (zh) 2020-10-09 2022-08-01 殷漢生技股份有限公司 吸入用奈米載體製劑
BR112023017538A2 (pt) 2021-03-03 2023-11-07 Pulmatrix Operating Co Inc Formulações de pó seco de di-hidroergotamina e métodos de uso
WO2022189662A1 (en) 2021-03-12 2022-09-15 Alvarius Pharmaceuticals Ltd. Compositions and methods for treating addictions comprising 5-meo-dmt
WO2022271684A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
US20230046340A1 (en) 2021-06-23 2023-02-16 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
CA3222595A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
CA3220923A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
US11919869B2 (en) 2021-10-29 2024-03-05 Gilead Sciences, Inc. CD73 compounds
WO2023122522A1 (en) 2021-12-20 2023-06-29 Pulmatrix Operating Company, Inc. Dry powder formulations of narrow spectrum kinase inhibitors
WO2023205389A1 (en) 2022-04-22 2023-10-26 Quench Medical Inc. Dry powder inhalation delivery of pharmaceuticals
WO2024040175A1 (en) 2022-08-18 2024-02-22 Pulmatrix Operating Company, Inc. Methods for treating cancer using inhaled angiogenesis inhibitor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device

Also Published As

Publication number Publication date
DE69000249T2 (de) 1993-03-11
DE69000249D1 (de) 1992-09-17
IT8919539A0 (it) 1989-02-23
US4995385A (en) 1991-02-26
IT1228459B (it) 1991-06-19
DK0388621T3 (da) 1992-11-02
ES2034781T3 (es) 1993-04-01
EP0388621B1 (de) 1992-08-12
EP0388621A1 (de) 1990-09-26

Similar Documents

Publication Publication Date Title
DE69000249D1 (de) Zur vollstaendigen entleerung der kapsel geeigneter inhalator.
SU656472A3 (ru) Аэрозольный ингал тор
ATE99967T1 (de) Inhalator zur einmaligen verwendung mit vorperforierter kapsel.
SE8504541D0 (sv) Dosing device
AU569743B2 (en) Medicinal inhaler
DK0773807T3 (da) Inhalator
SE8603252D0 (sv) Anordning for att tillfora lekemedel till patienter
ATE125161T1 (de) Einblasgerät für mehrfachdosierungen von pulverförmigen medikamenten.
DE69211450D1 (de) Inhalator zur Verabreichung von pulverförmigen Substanzen
ATE93151T1 (de) Wegwerfvorrichtung zur inhalation von arzneimitteln.
IT1225348B (it) Apparecchiatura per la somministrazione di farmaci pressurizzati in bombolette