EG16516A - Dosage inhalator - Google Patents

Dosage inhalator

Info

Publication number
EG16516A
EG16516A EG419/82A EG41982A EG16516A EG 16516 A EG16516 A EG 16516A EG 419/82 A EG419/82 A EG 419/82A EG 41982 A EG41982 A EG 41982A EG 16516 A EG16516 A EG 16516A
Authority
EG
Egypt
Prior art keywords
active compound
membrane
dosing
inhalator
air
Prior art date
Application number
EG419/82A
Other languages
English (en)
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Application granted granted Critical
Publication of EG16516A publication Critical patent/EG16516A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Disintegrating Or Milling (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Nozzles (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)
EG419/82A 1981-07-08 1982-07-10 Dosage inhalator EG16516A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8104239 1981-07-08

Publications (1)

Publication Number Publication Date
EG16516A true EG16516A (en) 1992-06-30

Family

ID=20344220

Family Applications (1)

Application Number Title Priority Date Filing Date
EG419/82A EG16516A (en) 1981-07-08 1982-07-10 Dosage inhalator

Country Status (30)

Country Link
US (1) US4524769A (enExample)
EP (1) EP0069715B1 (enExample)
JP (1) JPS5819269A (enExample)
KR (1) KR880001811B1 (enExample)
AT (1) ATE23272T1 (enExample)
AU (1) AU559297B2 (enExample)
CA (1) CA1178151A (enExample)
CY (1) CY1492A (enExample)
DE (1) DE3274065D1 (enExample)
DK (1) DK159052C (enExample)
EG (1) EG16516A (enExample)
ES (1) ES276079Y (enExample)
FI (1) FI77375C (enExample)
GR (1) GR76522B (enExample)
HK (1) HK64389A (enExample)
HU (1) HU189154B (enExample)
IE (1) IE53933B1 (enExample)
IL (1) IL66053A (enExample)
IN (1) IN158972B (enExample)
IS (1) IS1268B6 (enExample)
KE (1) KE3890A (enExample)
MY (1) MY100090A (enExample)
NO (1) NO154294C (enExample)
NZ (1) NZ201154A (enExample)
PH (1) PH22387A (enExample)
PL (1) PL132252B1 (enExample)
PT (1) PT75211B (enExample)
SG (1) SG37089G (enExample)
YU (1) YU45115B (enExample)
ZA (1) ZA824264B (enExample)

Families Citing this family (355)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
SE448277B (sv) * 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
US4929329A (en) * 1987-04-27 1990-05-29 Eg&G, Inc. Electrophoresis cassette system with apparatus and method for filling same
ATE138814T1 (de) * 1989-04-28 1996-06-15 Riker Laboratories Inc Inhalationsvorrichtung für trockenpulver
GB8909891D0 (en) * 1989-04-28 1989-06-14 Riker Laboratories Inc Device
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
US5192548A (en) * 1990-04-30 1993-03-09 Riker Laboratoires, Inc. Device
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
CA2092614C (en) * 1990-09-12 1996-04-09 Hans Bisgaard An inhaling device
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5304125A (en) * 1990-10-05 1994-04-19 The University Of North Carolina Apparatus for administering solid particulate aerosols to the lungs
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
JP3532204B2 (ja) * 1991-03-05 2004-05-31 アラダイム コーポレーション 流量計の圧力センサのドリフトオフセットを補正する方法および装置
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
DE4193534T1 (de) * 1991-04-15 1997-07-24 Leiras Oy Vorrichtung zum Abmessen einer Dosis pulverförmigen Arzneimittels für die Inhalation
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
FR2676929B1 (fr) * 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
CZ282291B6 (cs) * 1991-06-26 1997-06-11 Schering Corporation Dávkovač prášku inhalačního zařízení pro prášková léčiva
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6029661A (en) * 1991-08-26 2000-02-29 3M Innovative Properties Company Powder dispenser
DE69233258T2 (de) * 1991-08-26 2004-05-19 Minnesota Mining And Mfg. Co., Saint Paul Pulverspender
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
WO1993018812A1 (en) * 1992-03-25 1993-09-30 Tebro S.A. Powder jet dispenser for medicament inhalation therapies
SE9201411D0 (sv) * 1992-05-05 1992-05-05 Astra Ab Dosage inhalator with indicating/interupting means
ES2118234T3 (es) * 1992-05-29 1998-09-16 Ggu Gesundheits Umweltforsch Dispositivo para generar particulas inhalables de sustancias activas.
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
DK0665759T3 (da) * 1992-10-19 1999-08-23 Dura Pharma Inc Tørpulverinhalator
WO1994011044A2 (en) 1992-11-12 1994-05-26 Minnesota Mining And Manufacturing Company Powder inhaler
DE4239402A1 (de) * 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US6250300B1 (en) 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
KR0163472B1 (ko) * 1992-12-18 1998-11-16 에릭 에스. 딕커 분말 약품용 흡입기
FR2700279B1 (fr) * 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
CA2157584C (en) * 1993-03-03 1999-05-04 Paul Mulhauser Dry powder medicament inhalator
GB9306703D0 (en) * 1993-03-31 1993-05-26 Fisons Plc Inhalation device
DE4319514C2 (de) * 1993-06-14 2003-06-18 Sofotec Gmbh & Co Kg Pulverinhalator
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
US5830853A (en) * 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5506203C1 (en) * 1993-06-24 2001-02-06 Astra Ab Systemic administration of a therapeutic preparation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
DE4400084C2 (de) * 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form
PT101450B (pt) * 1994-02-02 1999-11-30 Hovione Produtos Farmaceuticos Novo dispositivo para inalacao
AU124387S (en) * 1994-03-25 1995-08-11 Astra Ab Training device for an inhaler
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
DE4415462C1 (de) * 1994-05-03 1995-08-31 Transcoject Marketing Gmbh Inhalator
US6165976A (en) * 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5983956A (en) 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5647347A (en) * 1994-10-21 1997-07-15 Glaxo Wellcome Inc. Medicament carrier for dry powder inhalator
SE9404439D0 (sv) * 1994-12-21 1994-12-21 Astra Ab Inhalation device
US6932962B1 (en) 1994-12-22 2005-08-23 Astrazeneca Ab Aerosol drug formulations containing hydrofluoroalkanes and alkyl saccharides
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
PT806945E (pt) * 1994-12-22 2003-09-30 Astrazeneca Ab Preparacao terapeutica para inalacao que contem a hormona paratiroide, hpt
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5612053A (en) * 1995-04-07 1997-03-18 Edward Mendell Co., Inc. Controlled release insufflation carrier for medicaments
US6428771B1 (en) 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
DE19518810A1 (de) * 1995-05-26 1996-11-28 Bayer Ag Nasal-Applikator
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
US5797392C1 (en) * 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
GB9626263D0 (en) 1996-12-18 1997-02-05 Innovata Biomed Ltd Powder inhaler
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700937D0 (sv) 1997-03-14 1997-03-14 Astra Ab Powder inhaler I
SE9700936D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
TW469832U (en) 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
US6260549B1 (en) * 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
GB9902493D0 (en) * 1999-02-05 1999-03-24 Glaxo Group Ltd Inhalation device
GB9905538D0 (en) 1999-03-10 1999-05-05 Glaxo Group Ltd A device
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
AU772798B2 (en) 1999-04-21 2004-05-06 1355540 Ontario Inc. Formulations for detecting asthma
EP1183061B2 (en) * 1999-06-05 2012-10-17 Innovata Biomed Limited Medicament delivery system
PT1808438E (pt) 1999-06-29 2015-01-14 Mannkind Corp Purificação e estabilização de péptidos e proteínas em agentes farmacêuticos
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
GB9917637D0 (en) * 1999-07-27 1999-09-29 Co Ordinated Drug Dev Improvements in or relating to inhaler devices
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
AU763041B2 (en) * 1999-08-25 2003-07-10 Alkermes, Inc. Modulation of release from dry powder formulations
GB9920839D0 (en) * 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
JP2003516200A (ja) * 1999-12-07 2003-05-13 オリオン コーポレーション 多数回投与パウダー吸入器
AU2729101A (en) 1999-12-21 2001-07-03 Rxkinetix, Inc. Particulate drug-containing products and method of manufacture
US6761909B1 (en) 1999-12-21 2004-07-13 Rxkinetix, Inc. Particulate insulin-containing products and method of manufacture
BR0108730A (pt) 2000-02-28 2002-11-05 Vectura Ltd Sistema, dispositivo e método para administração de uma droga, bocal de um dispositivo de administração de droga, dispositivo para administração de doses unitárias múltiplas de uma droga, métodos para preparação de um sistema de administração de droga e de uma formulação de droga e para tratamento de um paciente que necessita de doses múltiplas de uma droga, formulação de droga e multiparticulados
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
AU6124601A (en) * 2000-05-10 2001-11-20 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
AU2001275760B2 (en) 2000-08-05 2005-03-17 Glaxo Group Limited 6.alpha., 9.alpha.-difluoro-17.alpha.-'(2-furanylcarboxyl) oxy!-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid S-fluoromethyl ester as an anti-inflammatory agent
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
DE10047722A1 (de) * 2000-09-27 2002-04-11 Schuckmann Alfred Von Von Saugluftstrom des Benutzers aktivierbare Dosiervorrichtung
FI20002363A0 (fi) * 2000-10-27 2000-10-27 Orion Yhtymae Oyj Jauheinhalaattori
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
EP1345629A2 (en) 2000-12-29 2003-09-24 Advanced Inhalation Research, Inc. Particles for inhalation having sustained release properties
MXPA03007017A (es) * 2001-02-06 2004-09-13 Innovata Biomed Ltd Medicamentos.
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
EP1370521B1 (en) 2001-03-22 2007-12-19 Glaxo Group Limited Formanilide derivatives as beta2-adrenoreceptor agonists
WO2002092154A1 (en) * 2001-04-26 2002-11-21 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
BR0209271A (pt) 2001-04-30 2004-06-15 Glaxo Group Ltd Composto, uso de um composto composição farmacêutica, formulação em aerossol farmacêutica, método para o tratamento de um paciente humano ou animal com uma condição inflamatória e/ou alérgica, e, processo para a preparação de um composto
FI20011317A0 (fi) * 2001-06-20 2001-06-20 Orion Corp Jauheinhalaattori
DE10129703A1 (de) 2001-06-22 2003-01-02 Sofotec Gmbh & Co Kg Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
HU228508B1 (en) 2001-09-14 2013-03-28 Glaxo Group Ltd Phenethanolamine derivatives and pharmaceutical composition containing them
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
EP1487417A4 (en) 2001-09-17 2010-03-17 Glaxo Group Ltd DRY POWDER DRUG FORMULATIONS
EP1455755B1 (en) * 2001-11-20 2013-04-17 Civitas Therapeutics, Inc. Improved particulate compositions for pulmonary delivery
WO2003043603A1 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
EP1894591B1 (en) 2002-03-20 2013-06-26 MannKind Corporation Cartridge for an inhalation apparatus
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium
SE525027C2 (sv) 2002-04-12 2004-11-16 Microdrug Ag Anordning utgörande en pulverlufthyvel
SE524957C2 (sv) 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
US20030196661A1 (en) * 2002-04-19 2003-10-23 Miekka Richard George Power inhaler employing unit doses of powders in pressurized packages
US7271197B2 (en) 2002-04-25 2007-09-18 Glaxo Group Limited Phenethanolamine derivatives
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
DE10300032B3 (de) * 2003-01-03 2004-05-27 E. Braun Gmbh Pulverinhalator
US20040173211A1 (en) * 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
EP1587482A4 (en) * 2003-01-31 2010-08-25 Technion Res & Dev Foundation INFLAMMATORY COMPOSITIONS AND ITS USES
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
EP1624866A2 (en) * 2003-05-16 2006-02-15 Arriva Pharmaceuticals, Inc. Treatment of respiratory disease by inhalation of synthetic matrix metalloprotease inhibitors
TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
TW200519108A (en) 2003-07-17 2005-06-16 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
FI20031158A7 (fi) * 2003-08-15 2005-02-16 Medifiq Healthcare Oy Inhalaattori
WO2005025506A2 (en) * 2003-09-10 2005-03-24 Map Pharmaceuticals, Inc. Aerosol formulations for delivery of dihydroergotamine to the systemic circulation via pulmonary inhalation
SE0302665D0 (sv) * 2003-10-07 2003-10-07 Astrazeneca Ab Novel Process
ES2358673T3 (es) 2003-10-14 2011-05-12 Glaxo Group Limited Antagonistas de receptores de acetilcolina muscarínicos.
AP2006003575A0 (en) 2003-10-17 2006-04-30 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists.
US20070277820A1 (en) * 2003-10-27 2007-12-06 Timothy Crowder Blister packages and associated methods of fabricating dry powder drug containment systems
TW200524577A (en) 2003-11-04 2005-08-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
CA2547782A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
JP2007529513A (ja) 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
CA2561400A1 (en) 2004-04-02 2005-10-13 Glaxo Group Limited Chemical process and new crystalline form
RU2277940C2 (ru) * 2004-04-16 2006-06-20 Юрий Васильевич Иванов Ингалятор
EP1744800B1 (en) * 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MY144753A (en) 2004-04-27 2011-10-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2005112644A2 (en) 2004-05-13 2005-12-01 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
CA2569074C (en) 2004-05-31 2012-12-18 Almirall Prodesfarma S.A. Combinations comprising antimuscarinic agents and pde4 inhibitors
EP1786784B1 (en) 2004-08-20 2010-10-27 MannKind Corporation Catalysis of diketopiperazine synthesis
DK2314298T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Microparticles comprising diketopiperazinsalte for drug delivery
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
JP5156397B2 (ja) 2005-02-10 2013-03-06 グラクソ グループ リミテッド 予備分級技術を用いて乳糖を製造する方法及びその乳糖から形成させた医薬製剤
UY29440A1 (es) 2005-03-25 2006-10-02 Glaxo Group Ltd Nuevos compuestos
PE20100741A1 (es) 2005-03-25 2010-11-25 Glaxo Group Ltd COMPUESTOS DERIVADOS DE 3,4-DIHIDROPIRIMIDO[4,5-d]PIRIMIDIN-2(1H)-ONA COMO INHIBIDORES DE QUINASA p38
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
EP1937068A4 (en) 2005-08-18 2010-08-04 Glaxo Group Ltd ANTAGONISTS OF ACETYLCHOLINE MUSCARINIC RECEPTORS
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
BRPI0616071B8 (pt) 2005-09-14 2021-05-25 Mannkind Corp métodos de revestir uma micropartícula cristalina pré-formada em suspensão com um agente ativo
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
GB2433207B (en) 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
IN2015DN00888A (enExample) 2006-02-22 2015-07-10 Mannkind Corp
AU2007224178B2 (en) * 2006-03-03 2013-03-07 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
GB0605723D0 (en) 2006-03-23 2006-05-03 3M Innovative Properties Co Powder filling processes
JP2009533471A (ja) 2006-04-12 2009-09-17 バイオデル， インコーポレイテッド 即効型および長時間作用型組合せインスリン製剤
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
PT103481B (pt) * 2006-05-16 2008-08-01 Hovione Farmaciencia S A Inalador de uso simples e método de inalação
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
AU2008214205B2 (en) 2007-02-11 2014-04-24 Map Pharmaceuticals, Inc. Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
US20090211576A1 (en) * 2007-10-02 2009-08-27 Timo Lehtonen Safety and abuse deterrent improved device
JP5081771B2 (ja) * 2007-11-09 2012-11-28 日立オートモティブシステムズ株式会社 粉末薬剤投与器
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
EP2096105A1 (en) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
CN103190631B (zh) 2008-03-20 2016-01-20 维尔恩公司 非水性预乳液组合物及制备包含植物甾醇的饮料的方法
AU2009226019C1 (en) 2008-03-20 2014-02-20 Virun, Inc. Emulsions including a PEG-derivative of tocopherol
US20090241949A1 (en) * 2008-03-27 2009-10-01 Smutney Chad C Dry powder inhalation system
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
TWI592178B (zh) * 2008-06-13 2017-07-21 曼凱公司 用於藥物傳輸之乾粉吸入器及系統
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
US8337931B2 (en) * 2008-06-23 2012-12-25 Virun, Inc. Compositions containing non-polar compounds
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
UY32297A (es) 2008-12-22 2010-05-31 Almirall Sa Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CN102405044A (zh) * 2009-02-06 2012-04-04 南加利福尼亚大学 含有单萜的治疗组合物
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
LT3578169T (lt) 2009-02-26 2024-08-26 Glaxo Group Limited Farmaciniai preparatai, apimantys 4-{(1r)-2-[(6-{2-[(2,6-dichlorbenzil) oksi]etoksi}heksil)amino]-1-hidroksietil}-2-(hidroksimetil)fenolį
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
TWI547487B (zh) 2009-06-12 2016-09-01 曼凱公司 具限定比表面積之二酮基哌微粒子
AU2010260177A1 (en) 2009-06-16 2011-12-15 Merck Sharp & Dohme Corp. Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
MX2012000682A (es) 2009-07-15 2012-02-28 Theravance Inc Formas de bases libres cristalinas de un compuesto de bifenilo.
WO2011035128A1 (en) * 2009-09-17 2011-03-24 Mutual Pharmaceutical Company, Inc. Method of treating asthma with antiviral agents
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
CA2779488A1 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2011109635A1 (en) 2010-03-03 2011-09-09 Neonc Technologies Inc. Pharmaceutical compositions comprising monoterpenes
EP2563164B1 (en) 2010-03-23 2016-06-29 Virun, Inc. Nanoemulsion including sucrose fatty acid ester
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
US8741373B2 (en) 2010-06-21 2014-06-03 Virun, Inc. Compositions containing non-polar compounds
WO2012026963A2 (en) 2010-08-23 2012-03-01 Darren Rubin Systems and methods of aerosol delivery with airflow regulation
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
BR112013004698B1 (pt) 2010-08-27 2022-03-22 Neonc Technologies Inc. Composições farmacêuticas compreendendo derivados de poh
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
WO2012028663A1 (en) 2010-08-31 2012-03-08 Glaxo Group Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
ES2845185T3 (es) 2010-08-31 2021-07-26 Glaxosmithkline Ip Dev Ltd Productos farmacológicos para la inhalación de polvo seco que presentan propiedades de control de la humedad y procedimientos de administración de los mismos
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
US9297813B2 (en) 2010-11-11 2016-03-29 Agency For Science, Technology And Research Targeting metabolic enzymes in human cancer
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EP2463289A1 (en) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
WO2012078804A1 (en) 2010-12-07 2012-06-14 Respira Therapeutics, Inc. Dry powder inhaler
EP2651864B1 (en) 2010-12-17 2016-07-13 Neonc Technologies Inc. Methods and devices for using isoperillyl alcohol
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors
US8925726B2 (en) 2011-04-01 2015-01-06 Mannkind Corporation Blister package for pharmaceutical cartridges
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2518070A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors
EP2518071A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridine derivatives as PI3K inhibitors
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2527344A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2554544A1 (en) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1h)-one derivatives as jak inhibitors
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
JP6018640B2 (ja) 2011-10-24 2016-11-02 マンカインド コーポレイション 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2592077A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
SG10201610913PA (en) 2011-12-30 2017-02-27 Grifols Sa Alpha1-proteinase inhibitor for delaying the onset or progression of pulmonary exacerbations
SG11201404640YA (en) 2012-02-10 2014-09-26 Virun Inc Beverage compositions containing non-polar compounds
US10463815B2 (en) 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2647627A1 (en) 2012-04-02 2013-10-09 Almirall, S.A. Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one.
KR20150013463A (ko) 2012-04-27 2015-02-05 글락소 그룹 리미티드 신규 화합물
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
EP2666465A1 (en) 2012-05-25 2013-11-27 Almirall, S.A. Novel dosage and formulation
EP2668941A1 (en) 2012-05-31 2013-12-04 Almirall, S.A. Novel dosage form and formulation of abediterol
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
EP2874928B1 (en) 2012-07-19 2016-06-15 Adamis Pharmaceuticals Corporation Powder feeding apparatus
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
WO2014085474A1 (en) 2012-11-28 2014-06-05 Intercept Pharmaceuticals, Inc. Treatment of pulmonary disease
CA2892931A1 (en) 2012-12-18 2014-06-26 Almirall, S.A. Cyclohexyl and quinuclidinyl carbamate derivatives having ss2 adrenergic agonist and m3 muscarinic antagonist activities
TW201446767A (zh) 2013-02-15 2014-12-16 Almirall Sa 作為磷脂肌醇3-激酶抑製劑之吡咯並三嗪衍生物
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
WO2015091287A1 (en) 2013-12-19 2015-06-25 Almirall S.A. Dosage formulation comprising salmeterol and fluticasone propionate
EP3107606B1 (en) 2014-02-21 2024-08-28 David Brown Inhalation device for inhaling powders
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CA2948441A1 (en) 2014-05-12 2015-11-19 Glaxosmithkline Intellectual Property (No. 2) Limited Pharmaceutical compositions for treating infectious diseases
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
MX2017009112A (es) 2015-01-14 2018-06-15 Respira Therapeutics Inc Metodos y dispositivos de dispersion de polvo.
EP3872069A1 (en) 2015-02-12 2021-09-01 Neonc Technologies, Inc. Pharmaceutical compositions comprising perillyl alcohol derivatives
KR20170123315A (ko) 2015-03-11 2017-11-07 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Tslp 결합 단백질
WO2016170009A1 (en) 2015-04-21 2016-10-27 Almirall, S.A. Amino-substituted heterocyclic derivatives as sodium channel inhibitors
WO2016180753A1 (en) * 2015-05-08 2016-11-17 Iconovo Ab Dry powder inhaler
MX375352B (es) 2015-06-15 2025-03-06 Glaxosmithkline Ip Dev Ltd Reguladores de nrf2.
EP3766878B1 (en) 2015-06-15 2022-03-16 GlaxoSmithKline Intellectual Property Development Limited Nrf2 regulators
WO2016203400A1 (en) 2015-06-15 2016-12-22 Glaxosmithkline Intellectual Property Development Limited Nrf2 regulators
WO2016202800A1 (en) 2015-06-16 2016-12-22 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物
EP3371167A1 (en) 2015-10-06 2018-09-12 GlaxoSmithKline Intellectual Property Development Limited Arylcyclohexyl pyrazoles as nrf2 regulators
US10364256B2 (en) 2015-10-06 2019-07-30 Glaxosmithkline Intellectual Property Development Limited Biaryl pyrazoles as NRF2 regulators
WO2017076990A1 (en) 2015-11-05 2017-05-11 Almirall, S.A. Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產（第二）有限公司 Ｔｒｐｖ４拮抗劑
JP7106528B2 (ja) 2016-09-20 2022-07-26 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッド Ｔｒｐｖ４拮抗薬
JP7144411B2 (ja) 2016-11-30 2022-09-29 ネオンク テクノロジーズ インク． ペリリルアルコール－３－ブロモピルベート複合体及びがんの治療方法
KR20190088404A (ko) 2016-12-06 2019-07-26 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 3-(2,3-디히드로-1h-인덴-5-일)프로판산 유도체 및 nrf2 조절제로서의 그의 용도
JP2020500919A (ja) 2016-12-12 2020-01-16 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーターとしての３−カルボン酸ピロール
WO2018109642A1 (en) 2016-12-12 2018-06-21 Glaxosmithkline Intellectual Property Development Limited N-aryl pyrazoles as nrf2 regulators
JP2020502129A (ja) 2016-12-14 2020-01-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２アクチベーターとしての３−オキソ−１，４−ジアゼピニル化合物
JP2020502136A (ja) 2016-12-14 2020-01-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーターとしてのビスアリールアミド
ES2978187T3 (es) 2016-12-14 2024-09-06 Glaxosmithkline Intellectual Property Dev Heterociclos de bisarilo como activadores de NRF2
RU2019121673A (ru) 2016-12-15 2021-01-15 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Активаторы nrf2
WO2018109649A1 (en) 2016-12-15 2018-06-21 Glaxosmithkline Intellectual Property Development Limited Ether linked triazoles as nrf2 regulators
WO2018174938A1 (en) 2017-03-23 2018-09-27 Virun, Inc. Stable dry powders and emulsions containing probiotics and mucoadhesive protein
EP3615545B1 (en) 2017-04-24 2021-09-01 Cocrystal Pharma, Inc. Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
WO2019066702A1 (en) 2017-09-28 2019-04-04 Iconovo Ab DRY POWDER INHALER COMPRISING MEANS FOR IMPROVING DISPERSION
WO2019116231A1 (en) 2017-12-11 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
JP2021505636A (ja) 2017-12-11 2021-02-18 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ 急性肺傷害、急性呼吸促迫症候群および多臓器不全症候群の処置のためのｎｒｆ２アクチベーター
GB201720989D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
CN111868063B (zh) 2018-01-17 2023-08-01 葛兰素史克知识产权开发有限公司 PI4KIIIβ抑制剂
KR20200118084A (ko) 2018-02-08 2020-10-14 네온씨 테크놀로지스, 아이엔씨. 혈액 뇌 장벽의 투과 방법
JP2021524469A (ja) 2018-05-23 2021-09-13 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２アクチベーターとしてのインダン
EP3829719B1 (en) 2018-07-27 2025-04-02 Cocrystal Pharma, Inc. Pyrrolo[2,3-b]pyridin derivatives as inhibitors of influenza virus replication
CN113286793B (zh) 2018-09-10 2024-04-05 共结晶制药公司 吡咯并吡嗪和吡啶并三嗪类流感病毒复制抑制剂
KR102620705B1 (ko) 2018-10-11 2024-01-04 삼성전자주식회사 전자 장치 및 그의 동작 방법
FI3866778T3 (fi) 2018-10-17 2023-03-21 Cocrystal Pharma Inc Influenssa viruksen replikaation estäjien yhdistelmät
EP3880251B1 (en) 2018-11-13 2025-04-09 Cocrystal Pharma, Inc. Formulations of influenza therapeutics
EP3887355A1 (en) 2018-11-26 2021-10-06 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
CA3123725A1 (en) * 2019-02-15 2020-08-20 Iconovo Ab Inhaler
CA3132082A1 (en) 2019-03-14 2020-09-17 Om Pharma Sa Method of treating and/or preventing asthma, asthma exacerbations, allergic asthma and/or associated conditions with microbiota related to respiratory disorders
CN113840615A (zh) 2019-03-14 2021-12-24 Om药物公司 制备稳定细菌提取物的方法及其作为药物的用途
GB201908536D0 (en) 2019-06-13 2019-07-31 Glaxosmithkline Ip Dev Ltd Compounds
WO2021188620A1 (en) 2020-03-17 2021-09-23 Cocrystal Pharma Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
WO2021206876A1 (en) 2020-04-10 2021-10-14 Cocrystal Pharma, Inc. Inhibitors of norovirus and coronavirus replication
US20230158125A1 (en) 2020-04-20 2023-05-25 Sorrento Therapeutics, Inc. Pulmonary Administration of ACE2 Polypeptides
WO2022175425A1 (en) 2021-02-22 2022-08-25 Glaxosmithkline Intellectual Property Development Limited Inhaled mtor kinase inhibitors for use in the treatment or the prevention of a respiratory rna virus infection
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
JP2024530920A (ja) 2021-08-03 2024-08-27 コクリスタル ファーマ，インコーポレイテッド コロナウイルスに対する阻害剤
EP4511000A1 (en) 2022-04-22 2025-02-26 Quench Medical Inc. Dry powder inhalation delivery of pharmaceuticals
WO2023232976A1 (en) 2022-06-03 2023-12-07 Ags Therapeutics Sas Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11485A (en) * 1854-08-08 Befbigeeatob fobj maeine ejstgiites
US2641254A (en) * 1948-10-18 1953-06-09 Frederick M Turnbull Applicator
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2573918A (en) * 1949-11-05 1951-11-06 Vick Chemical Company Device for dispensing medicaments
US2581182A (en) * 1950-03-14 1952-01-01 Abbott Lab Inhaler
DE1813993C3 (de) * 1968-12-11 1974-01-24 Paul Ritzau Pari-Werk Kg, 8135 Soecking Vorrichtung zum Zerstäuben und Vernebeln von flüssigen oder pulverförmigen Stoffen
US3653380A (en) * 1970-02-16 1972-04-04 American Cyanamid Co Aerosol powder dosage dispensing device
US4003500A (en) * 1970-12-31 1977-01-18 Hoechst Aktiengesellschaft Metering device
US3831606A (en) * 1971-02-19 1974-08-27 Alza Corp Auto inhaler
DE2502251A1 (de) * 1975-01-17 1976-07-22 Schering Ag Vorrichtung zur inhalation pulverfoermiger feststoffe
SU651766A1 (ru) * 1975-11-25 1979-03-15 Литовский Научно-Исследовательский Институт Ветеринарии Электроаэрозольный аппарат дл вакцинации животных
SU570775A1 (ru) * 1976-02-02 1977-08-30 Институт Теоретических Проблем Химической Технологии Ан Азербайджанской Сср Объемный микродозатор жидкости
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2716323C2 (de) * 1977-04-07 1986-03-13 Schering AG, 1000 Berlin und 4709 Bergkamen Vorrichtung zur Inhalation von Arzneimitteln
DE2807866C2 (de) * 1978-02-23 1979-09-20 Plasmainvent Ag, Zug (Schweiz) Vorrichtung zum dosierten Zuführen von Pulver zu einer Pulververarbeitungseinheit
DE2837040C2 (de) * 1978-08-24 1982-10-21 Siemens AG, 1000 Berlin und 8000 München Flüssigkeitstransportsystem für ein Inhalationsgerät
SU799766A1 (ru) * 1979-01-18 1981-01-30 Московский Научно-Исследовательс-Кий Институт Вакцин И Сывороток Им.И.И.Мечникова Устройство дл распылени порош-КООбРАзНыХ ВЕщЕСТВ
IT7920688U1 (it) * 1979-02-05 1980-08-05 Chiesi Paolo Inalatore per sostanze medicamentose pulverulente, con combinata funzione di dosatore
US4253591A (en) * 1979-06-18 1981-03-03 General Electric Company Mercury doser
US4262666A (en) * 1979-10-24 1981-04-21 Nelson Byron G Inhalator-breathing apparatus

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IL66053A (en) 1987-10-30
ZA824264B (en) 1983-04-27
IE821495L (en) 1983-01-08
US4524769A (en) 1985-06-25
DK159052B (da) 1990-08-27
NZ201154A (en) 1984-08-24
DK304482A (da) 1983-01-09
NO822370L (no) 1983-01-10
CA1178151A (en) 1984-11-20
AU559297B2 (en) 1987-03-05
ATE23272T1 (de) 1986-11-15
PT75211A (en) 1982-08-01
YU141482A (en) 1987-04-30
GR76522B (enExample) 1984-08-10
YU45115B (en) 1992-03-10
PL132252B1 (en) 1985-02-28
SG37089G (en) 1989-10-13
MY100090A (en) 1989-08-18
PH22387A (en) 1988-08-12
PL237363A1 (en) 1983-02-28
HU189154B (en) 1986-06-30
EP0069715B1 (en) 1986-11-05
IS1268B6 (is) 1987-05-27
KR840000250A (ko) 1984-02-18
KE3890A (en) 1989-09-01
NO154294C (no) 1986-09-03
IN158972B (enExample) 1987-02-28
DE3274065D1 (de) 1986-12-11
FI822423L (fi) 1983-01-09
FI77375C (fi) 1989-03-10
JPS5819269A (ja) 1983-02-04
AU8560882A (en) 1983-01-13
NO154294B (no) 1986-05-20
FI822423A0 (fi) 1982-07-07
KR880001811B1 (ko) 1988-09-19
IE53933B1 (en) 1989-04-26
DK159052C (da) 1991-02-04
PT75211B (en) 1985-11-12
HK64389A (en) 1989-08-18
CY1492A (en) 1990-02-16
IS2734A7 (is) 1983-01-09
EP0069715A1 (en) 1983-01-12
ES276079U (es) 1984-05-01
FI77375B (fi) 1988-11-30
JPH0147190B2 (enExample) 1989-10-12
ES276079Y (es) 1984-12-16

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