NO20072575L - Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyre - Google Patents
Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyreInfo
- Publication number
- NO20072575L NO20072575L NO20072575A NO20072575A NO20072575L NO 20072575 L NO20072575 L NO 20072575L NO 20072575 A NO20072575 A NO 20072575A NO 20072575 A NO20072575 A NO 20072575A NO 20072575 L NO20072575 L NO 20072575L
- Authority
- NO
- Norway
- Prior art keywords
- strains
- epa
- yarrowia lipolytica
- high production
- eicosapentaenoic acid
- Prior art date
Links
- 241000235015 Yarrowia lipolytica Species 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 title 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 title 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 title 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 title 1
- 108700016155 Acyl transferases Proteins 0.000 abstract 2
- 102000057234 Acyl transferases Human genes 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 102000045404 acyltransferase activity proteins Human genes 0.000 abstract 1
- 108700014220 acyltransferase activity proteins Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
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- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
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- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
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- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
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Abstract
Konstruerte stammer av den oljeholdige gjæren Yarrowia lipolytica er i stand til å produsere mer enn 25% eicosaspentaensyre (EPA), en (?-3 polyumettet fettsyre) i den totale oljefraksjonen som er beskrevet. Disse stammene omfatter ulike kimære gener som uttrykker heterologe desaturaser, elongaser og acyltransferaser og omfatter eventuelt ulike native desaturase og acyltransferase knockouts for å muliggjøre syntese og høy akkumulering av EPA. Produksjonsvertsceller er stilt krav om, som også fremgangsmåter for å produsere EPA med nevnte vertseeller.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62481204P | 2004-11-04 | 2004-11-04 | |
| PCT/US2005/040255 WO2006052870A2 (en) | 2004-11-04 | 2005-11-03 | High eicosapentaenoic acid producing strains of yarrowia lipolytica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072575L true NO20072575L (no) | 2007-08-01 |
Family
ID=36337096
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072517A NO20072517L (no) | 2004-11-04 | 2007-05-15 | Hoy-arakidonsyreproduserende stammer av Yarrowia Lipolytica |
| NO20072516A NO20072516L (no) | 2004-11-04 | 2007-05-16 | Docosaheksaensyreproduserende stammer av Yarrowia Lipolytica |
| NO20072575A NO20072575L (no) | 2004-11-04 | 2007-05-21 | Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyre |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072517A NO20072517L (no) | 2004-11-04 | 2007-05-15 | Hoy-arakidonsyreproduserende stammer av Yarrowia Lipolytica |
| NO20072516A NO20072516L (no) | 2004-11-04 | 2007-05-16 | Docosaheksaensyreproduserende stammer av Yarrowia Lipolytica |
Country Status (9)
| Country | Link |
|---|---|
| US (8) | US7550286B2 (no) |
| EP (5) | EP1807527B1 (no) |
| JP (3) | JP5129574B2 (no) |
| KR (3) | KR20070085669A (no) |
| CN (4) | CN101437951A (no) |
| CA (3) | CA2585178C (no) |
| DK (4) | DK2458000T3 (no) |
| NO (3) | NO20072517L (no) |
| WO (3) | WO2006052870A2 (no) |
Families Citing this family (173)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8313911B2 (en) * | 2003-05-07 | 2012-11-20 | E I Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
| US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
| EP2172536B1 (de) | 2003-08-01 | 2016-05-04 | BASF Plant Science GmbH | Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen |
| EP3543324B1 (de) | 2004-02-27 | 2022-11-30 | BASF Plant Science GmbH | Verfahren zur herstellung mehrfach ungesättigten fettsäuren in transgenen pflanzen |
| CN102559364B (zh) | 2004-04-22 | 2016-08-17 | 联邦科学技术研究组织 | 用重组细胞合成长链多不饱和脂肪酸 |
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| US7470532B2 (en) | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
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