NO20072575L - Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyre - Google Patents

Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyre

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Publication number
NO20072575L
NO20072575L NO20072575A NO20072575A NO20072575L NO 20072575 L NO20072575 L NO 20072575L NO 20072575 A NO20072575 A NO 20072575A NO 20072575 A NO20072575 A NO 20072575A NO 20072575 L NO20072575 L NO 20072575L
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NO
Norway
Prior art keywords
strains
epa
yarrowia lipolytica
high production
eicosapentaenoic acid
Prior art date
Application number
NO20072575A
Other languages
English (en)
Inventor
Stephen K Picataggio
Hongxiang Zhang
Quinn Qun Zhu
Howard G Damude
Peter John Gillies
Daniel Joseph Macool
James John Ragghianti
Zhixiong Xue
Dana M Walters Pollak
Narendra S Yadav
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of NO20072575L publication Critical patent/NO20072575L/no

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    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
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Abstract

Konstruerte stammer av den oljeholdige gjæren Yarrowia lipolytica er i stand til å produsere mer enn 25% eicosaspentaensyre (EPA), en (?-3 polyumettet fettsyre) i den totale oljefraksjonen som er beskrevet. Disse stammene omfatter ulike kimære gener som uttrykker heterologe desaturaser, elongaser og acyltransferaser og omfatter eventuelt ulike native desaturase og acyltransferase knockouts for å muliggjøre syntese og høy akkumulering av EPA. Produksjonsvertsceller er stilt krav om, som også fremgangsmåter for å produsere EPA med nevnte vertseeller.
NO20072575A 2004-11-04 2007-05-21 Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyre NO20072575L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62481204P 2004-11-04 2004-11-04
PCT/US2005/040255 WO2006052870A2 (en) 2004-11-04 2005-11-03 High eicosapentaenoic acid producing strains of yarrowia lipolytica

Publications (1)

Publication Number Publication Date
NO20072575L true NO20072575L (no) 2007-08-01

Family

ID=36337096

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20072517A NO20072517L (no) 2004-11-04 2007-05-15 Hoy-arakidonsyreproduserende stammer av Yarrowia Lipolytica
NO20072516A NO20072516L (no) 2004-11-04 2007-05-16 Docosaheksaensyreproduserende stammer av Yarrowia Lipolytica
NO20072575A NO20072575L (no) 2004-11-04 2007-05-21 Stammer av Yarrowia Lipolytica som har hoy produksjon av eikosapentaensyre

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20072517A NO20072517L (no) 2004-11-04 2007-05-15 Hoy-arakidonsyreproduserende stammer av Yarrowia Lipolytica
NO20072516A NO20072516L (no) 2004-11-04 2007-05-16 Docosaheksaensyreproduserende stammer av Yarrowia Lipolytica

Country Status (9)

Country Link
US (8) US7588931B2 (no)
EP (5) EP1807526A4 (no)
JP (3) JP5139806B2 (no)
KR (3) KR20070085669A (no)
CN (4) CN101437953B (no)
CA (3) CA2584719C (no)
DK (4) DK1807527T3 (no)
NO (3) NO20072517L (no)
WO (3) WO2006052870A2 (no)

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US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP2166071B1 (de) 2003-08-01 2016-01-06 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
CA2563875C (en) 2004-04-22 2015-06-30 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CN102559364B (zh) 2004-04-22 2016-08-17 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
PT1766023E (pt) * 2004-06-04 2010-12-09 Fluxome Sciences As Células metabolicamente manipuladas para a produção de ácidos gordos poliinsaturados
US20060094102A1 (en) * 2004-11-04 2006-05-04 Zhixiong Xue Ammonium transporter promoter for gene expression in oleaginous yeast
US7588931B2 (en) 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
US7879591B2 (en) 2004-11-04 2011-02-01 E.I. Du Pont De Nemours And Company High eicosapentaenoic acid producing strains of Yarrowia lipolytica
GB0503657D0 (en) 2005-02-22 2005-03-30 Fluxome Sciences As Metabolically engineered cells for the production of resveratrol or an oligomeric or glycosidically-bound derivative thereof
US7470532B2 (en) * 2005-10-19 2008-12-30 E.I. Du Pont De Nemours And Company Mortierella alpina C16/18 fatty acid elongase
US20070118929A1 (en) * 2005-11-23 2007-05-24 Damude Howard G Delta-9 elongases and their use in making polyunsaturated fatty acids
AR059376A1 (es) * 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
US7465793B2 (en) 2006-04-20 2008-12-16 E.I. Du Pont De Nemours And Company Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids
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