DE3783396T2 - Verfahren zur herstellung von bishomo-gamma-linolensaeure und eicosapentaensaeure. - Google Patents

Verfahren zur herstellung von bishomo-gamma-linolensaeure und eicosapentaensaeure.

Info

Publication number
DE3783396T2
DE3783396T2 DE8787305995T DE3783396T DE3783396T2 DE 3783396 T2 DE3783396 T2 DE 3783396T2 DE 8787305995 T DE8787305995 T DE 8787305995T DE 3783396 T DE3783396 T DE 3783396T DE 3783396 T2 DE3783396 T2 DE 3783396T2
Authority
DE
Germany
Prior art keywords
acid
eicosapentic
bishomo
gamma
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787305995T
Other languages
English (en)
Other versions
DE3783396D1 (de
Inventor
Yoshifumi Shinmen
Hideaki - Kinomoto-Cho Yamada
Sakayu Shimizu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61158651A external-priority patent/JPH0712315B2/ja
Priority claimed from JP61158650A external-priority patent/JPH0722513B2/ja
Application filed by Suntory Ltd filed Critical Suntory Ltd
Publication of DE3783396D1 publication Critical patent/DE3783396D1/de
Application granted granted Critical
Publication of DE3783396T2 publication Critical patent/DE3783396T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8787305995T 1986-07-08 1987-07-07 Verfahren zur herstellung von bishomo-gamma-linolensaeure und eicosapentaensaeure. Expired - Lifetime DE3783396T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61158651A JPH0712315B2 (ja) 1986-07-08 1986-07-08 エイコサペンタエン酸及びこれを含有する脂質の製造方法
JP61158650A JPH0722513B2 (ja) 1986-07-08 1986-07-08 ビスホモ―γ―リノレン酸及びこれを含有する脂質の製造方法

Publications (2)

Publication Number Publication Date
DE3783396D1 DE3783396D1 (de) 1993-02-18
DE3783396T2 true DE3783396T2 (de) 1993-07-29

Family

ID=26485695

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787305995T Expired - Lifetime DE3783396T2 (de) 1986-07-08 1987-07-07 Verfahren zur herstellung von bishomo-gamma-linolensaeure und eicosapentaensaeure.

Country Status (6)

Country Link
US (1) US5401646A (de)
EP (1) EP0252716B1 (de)
CA (1) CA1317901C (de)
DE (1) DE3783396T2 (de)
ES (1) ES2052564T3 (de)
GR (1) GR3006757T3 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034321A (en) * 1987-08-19 1991-07-23 Idemitsu Petrochemical Co., Ltd. Method for the production of lipids containing bis-homo-γ-linolenic acid
JP2746371B2 (ja) * 1987-12-21 1998-05-06 サントリー株式会社 ビスホモ−γ−リノレン酸及びこれを含有する脂質の製造方法
US5591446A (en) * 1989-04-04 1997-01-07 Beiersdorf, A.G. Methods and agents for the prophylaxis of atopy
US5093249A (en) * 1989-05-24 1992-03-03 Idemitsu Petrochemical Co., Ltd. Process for production of dihomo-γ-linolenic acid and inhibitor for unsaturation reaction at Δ5-position of fatty acid
EP0522470B1 (de) * 1991-07-11 1996-05-22 Idemitsu Petrochemical Co., Ltd. Triglyceride enthaltende trockene Zellfragmente und Verfahren zu deren Herstellung
CN1035627C (zh) * 1991-07-30 1997-08-13 中国科学院沈阳应用生态研究所 r-亚麻醉及以其为主的生物制剂的制备方法
JP3995290B2 (ja) * 1996-08-23 2007-10-24 サントリー株式会社 オメガ９系高度不飽和脂肪酸及びそれを含有する脂質の製造方法
JP3792309B2 (ja) * 1996-08-30 2006-07-05 サントリー株式会社 不飽和脂肪酸含有油脂の製造方法
DK0960943T3 (en) 1996-12-27 2014-02-24 Suntory Holdings Ltd MEDIA FOR CULTIVATION OF MICRO-ORGANISMS AND METHOD FOR PRODUCING unsaturated fatty acids or lipids containing DEM
EP0972844B1 (de) * 1997-03-04 2008-09-17 Suntory Limited Verfahren zur herstellung von hochungesättigten fettsäuren und hochungesättigte fettsäuren enthaltendes lipid
EP1122304B1 (de) 1999-08-13 2011-10-19 Suntory Holdings Limited Lipidausscheidender mikroorganismus und verfahren zur herstellung des lipids und lipidkugeln mit darin eingeschlossenem lipid durch verwendung von mikroorganismen
DE10106660A1 (de) * 2001-02-12 2002-08-29 Celanese Ventures Gmbh Verfahren zur Herstellung von gamma-Linolensäure aus einer Ciliaten-Kultur durch Zusatz geeigneter Vorläufermoleküle zu dem Kulturmedium
JP4088097B2 (ja) 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
US7550286B2 (en) * 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
SG176463A1 (en) 2005-02-22 2011-12-29 Univ Michigan Small molecule inhibitors of mdm2 and uses thereof
US8323935B2 (en) * 2007-10-03 2012-12-04 E I Du Pont De Nemours And Company Optimized strains of Yarrowia lipolytica for high eicosapentaenoic acid production
KR101668833B1 (ko) * 2008-07-16 2016-10-25 닛산 가가쿠 고교 가부시키 가이샤 포지티브형 레지스트 조성물 및 마이크로렌즈의 제조방법
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CA2787344C (en) 2010-01-19 2018-03-20 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
WO2011133610A1 (en) 2010-04-22 2011-10-27 E. I. Du Pont De Nemours And Company Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
US20120207912A1 (en) 2010-08-11 2012-08-16 E.I. Du Pont De Nemours And Company Aquaculture meat products
US20120040076A1 (en) 2010-08-11 2012-02-16 E. I. Du Pont De Nemours And Company Aquaculture feed compositions
CA2805891A1 (en) 2010-08-11 2012-02-16 Scott E. Nichols A sustainable aquaculture feeding strategy
JP2013535987A (ja) 2010-08-26 2013-09-19 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高レベルのエイコサペンタエン酸生産のための組換え微生物宿主細胞
WO2012109563A1 (en) * 2011-02-11 2012-08-16 E. I. Du Pont De Nemours And Company Purification of triglyceride oil from microbial sources using short path distillation
BR112014001126B1 (pt) 2011-07-21 2022-05-10 Dsm Ip Assets B.V Composição contendo óleo microbiano refinado e forma de dosagem oral
NZ709083A (en) 2012-12-24 2020-07-31 Qualitas Health Inc Eicosapentaenoic acid (epa) formulations
JP6026709B1 (ja) 2014-12-25 2016-11-16 国立大学法人京都大学 新規ω３不飽和脂肪酸酵素およびエイコサペンタエン酸の製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485173A (en) * 1981-01-19 1984-11-27 Cpc International Inc. Preparation of fats and oils
JPS5822199B2 (ja) * 1981-03-03 1983-05-07 工業技術院長 γ−リノレン酸含量の高い脂質の製造方法
JPS59130191A (ja) * 1983-01-12 1984-07-26 Agency Of Ind Science & Technol γ−リノレン酸含量の高い脂質の製造方法
JPS59205979A (ja) * 1983-05-11 1984-11-21 Agency Of Ind Science & Technol 微生物菌体の製造方法
DE3470061D1 (en) * 1984-02-09 1988-04-28 Agency Ind Science Techn A method for the preparation of a fungal body and a lipid rich in gamma-linolenic acid therefrom
JPS60168391A (ja) * 1984-02-09 1985-08-31 Agency Of Ind Science & Technol γ‐リノレン酸濃縮物の製造方法
JPS60259192A (ja) * 1984-06-05 1985-12-21 Agency Of Ind Science & Technol 微生物脂質の生産方法
FR2574089B1 (fr) * 1984-12-03 1987-04-10 Inst Nat Sante Rech Med Procede de production d'acides gras, en particulier d'acide g-linoleique a partir de tetrahymena, produits obtenus et preparation medicamenteuse ou alimentaire contenant de l'acide g-linolenique ou ses derives en tant qu'agent anti-agregation plaquettaire
JPH0716424B2 (ja) * 1985-10-01 1995-03-01 ライオン株式会社 アラキドン酸含有脂質の製造方法

Also Published As

Publication number Publication date
DE3783396D1 (de) 1993-02-18
GR3006757T3 (de) 1993-06-30
EP0252716A2 (de) 1988-01-13
CA1317901C (en) 1993-05-18
US5401646A (en) 1995-03-28
EP0252716B1 (de) 1993-01-07
EP0252716A3 (en) 1988-10-05
ES2052564T3 (es) 1994-07-16

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