BRPI0913138A2 - célula hospedeira eucariótica oleaginosa transgênica, célula de levedura eucariótica oleaginosa transgênica, óleo ou lipídeos, método para aumentar o teor de lipídeo total de uma célula hospedeira eucariótica oleaginosa e método para aumentar o teor total de ácidos graxos poliinsaturados no óleo microbiano - Google Patents
célula hospedeira eucariótica oleaginosa transgênica, célula de levedura eucariótica oleaginosa transgênica, óleo ou lipídeos, método para aumentar o teor de lipídeo total de uma célula hospedeira eucariótica oleaginosa e método para aumentar o teor total de ácidos graxos poliinsaturados no óleo microbianoInfo
- Publication number
- BRPI0913138A2 BRPI0913138A2 BRPI0913138A BRPI0913138A BRPI0913138A2 BR PI0913138 A2 BRPI0913138 A2 BR PI0913138A2 BR PI0913138 A BRPI0913138 A BR PI0913138A BR PI0913138 A BRPI0913138 A BR PI0913138A BR PI0913138 A2 BRPI0913138 A2 BR PI0913138A2
- Authority
- BR
- Brazil
- Prior art keywords
- oleaginous
- eukaryotic
- increasing
- transgenic
- host cell
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6431—Linoleic acids [18:2[n-6]]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6432—Eicosapentaenoic acids [EPA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9300708P | 2008-08-29 | 2008-08-29 | |
PCT/US2009/055376 WO2010025374A2 (en) | 2008-08-29 | 2009-08-28 | Manipulation of snf1 protein kinase activity for altered oil content in oleaginous organisms |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0913138A2 true BRPI0913138A2 (pt) | 2016-05-31 |
Family
ID=41722312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0913138A BRPI0913138A2 (pt) | 2008-08-29 | 2009-08-28 | célula hospedeira eucariótica oleaginosa transgênica, célula de levedura eucariótica oleaginosa transgênica, óleo ou lipídeos, método para aumentar o teor de lipídeo total de uma célula hospedeira eucariótica oleaginosa e método para aumentar o teor total de ácidos graxos poliinsaturados no óleo microbiano |
Country Status (9)
Country | Link |
---|---|
US (1) | US8435758B2 (pt) |
EP (1) | EP2324120B1 (pt) |
JP (1) | JP5656836B2 (pt) |
CN (1) | CN102216464B (pt) |
AU (1) | AU2009285590B2 (pt) |
BR (1) | BRPI0913138A2 (pt) |
CA (1) | CA2734264A1 (pt) |
DK (1) | DK2324120T3 (pt) |
WO (1) | WO2010025374A2 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012135777A1 (en) | 2011-04-01 | 2012-10-04 | E. I. Du Pont De Nemours And Company | Yarrowia esterase/lipase promoter regions for gene expression in yeast |
US8735094B2 (en) | 2011-04-05 | 2014-05-27 | E I Du Pont De Nemours And Company | Yarrowia n-alkane-hydroxylating cytochrome P450 promoter regions for gene expression in yeast |
WO2012138612A1 (en) | 2011-04-07 | 2012-10-11 | E. I. Du Pont De Nemours And Company | Yarrowia peroxisomal 2,4-dienoyl-coa reductase promoter regions for gene expression in yeast |
CN109468241A (zh) * | 2011-10-19 | 2019-03-15 | 麻省理工学院 | 工程改造的微生物及用于微生物油生产的方法 |
CN102586289A (zh) * | 2011-12-02 | 2012-07-18 | 华中农业大学 | 粘红酵母乙酰辅酶a羧化酶基因及其克隆、功能验证方法和应用 |
CN108064268A (zh) * | 2014-05-29 | 2018-05-22 | 诺沃吉公司 | 增加脂质产生和优化脂质组成 |
AU2015266724B2 (en) | 2014-05-29 | 2021-09-23 | Ginkgo Bioworks, Inc. | Increasing lipid production in oleaginous yeast |
US20170145449A1 (en) * | 2014-06-11 | 2017-05-25 | Institut National De La Recherche Agronomique | Improved lipid accumulation in Yarrowia lipolytica strains by overexpression of hexokinase and new strains thereof |
US10513711B2 (en) | 2014-08-13 | 2019-12-24 | Dupont Us Holding, Llc | Genetic targeting in non-conventional yeast using an RNA-guided endonuclease |
CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
CN108624600B (zh) * | 2018-05-22 | 2021-06-18 | 昆明理工大学 | 锌指转录因子基因RkMsn4的用途 |
AU2020340444A1 (en) * | 2019-08-30 | 2022-04-14 | Lygos, Inc. | Recombinant host cells for the production of malonate |
KR102335426B1 (ko) * | 2020-01-07 | 2021-12-06 | 삼성전기주식회사 | 코일 부품 |
CN113528589B (zh) * | 2020-03-09 | 2023-03-24 | 山东省农业科学院生物技术研究中心 | 一种调控集胞藻中不饱和脂肪酸合成的方法及其应用 |
CN112662688B (zh) * | 2021-01-25 | 2022-04-22 | 山东省果树研究所 | 核桃SnRK1蛋白激酶编码基因JrSnRK1在油脂合成与积累中的应用 |
CN114317466B (zh) * | 2022-01-04 | 2023-10-27 | 中山大学附属第三医院 | 一种突变acc1蛋白及其用途 |
CN116790647B (zh) * | 2023-02-06 | 2024-04-16 | 森瑞斯生物科技(深圳)有限公司 | 一种低背景、高信号强度的2-吡咯烷酮生物传感器及应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105730B1 (en) * | 1999-07-12 | 2006-09-12 | Monsanto Technology L.L.C. | Nucleic acid molecules and other molecules associated with sterol synthesis and metabolism |
US20060263864A1 (en) | 1999-10-20 | 2006-11-23 | Robert Busby | Methods for improving secondary metabolite production of fungi |
US6949356B1 (en) * | 1999-10-20 | 2005-09-27 | Microbia, Inc. | Methods for improving secondary metabolite production in fungi |
US7238482B2 (en) | 2003-05-07 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Production of polyunsaturated fatty acids in oleaginous yeasts |
US7267976B2 (en) | 2003-07-02 | 2007-09-11 | E.I. Du Pont De Nemours And Company | Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts |
US7504259B2 (en) * | 2003-11-12 | 2009-03-17 | E. I. Du Pont De Nemours And Company | Δ12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast |
EP1685239B1 (en) * | 2003-11-12 | 2014-05-21 | E.I. Du Pont De Nemours And Company | Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast |
WO2005049805A2 (en) | 2003-11-14 | 2005-06-02 | E.I. Dupont De Nemours And Company | Fructose-bisphosphate aldolase regulatory sequences for gene expression in oleaginous yeast |
EP1789561B1 (en) * | 2004-07-16 | 2010-01-06 | CropDesign N.V. | Plants having improved growth characteristics and method for making the same |
US7465564B2 (en) | 2004-08-10 | 2008-12-16 | E.I. Du Pont De Nemours And Company | Production of γ-linolenic acid in oleaginous yeast |
US7588931B2 (en) | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
US7273746B2 (en) | 2004-11-04 | 2007-09-25 | E.I. Dupont De Nemours And Company | Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms |
US7732680B2 (en) * | 2005-03-16 | 2010-06-08 | Metabolix, Inc. | Chemically inducible expression of biosynthetic pathways |
US7943365B2 (en) | 2007-05-03 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Δ-5 desaturases and their use in making polyunsaturated fatty acids |
CN101970638B (zh) | 2007-10-03 | 2015-02-11 | 纳幕尔杜邦公司 | 用于高水平生产二十碳五烯酸的优化解脂耶氏酵母菌株 |
-
2009
- 2009-08-28 AU AU2009285590A patent/AU2009285590B2/en not_active Ceased
- 2009-08-28 CN CN200980143092.6A patent/CN102216464B/zh not_active Expired - Fee Related
- 2009-08-28 CA CA2734264A patent/CA2734264A1/en not_active Abandoned
- 2009-08-28 DK DK09810662.8T patent/DK2324120T3/en active
- 2009-08-28 JP JP2011525234A patent/JP5656836B2/ja not_active Expired - Fee Related
- 2009-08-28 EP EP09810662.8A patent/EP2324120B1/en not_active Not-in-force
- 2009-08-28 BR BRPI0913138A patent/BRPI0913138A2/pt active Search and Examination
- 2009-08-28 US US12/549,439 patent/US8435758B2/en active Active
- 2009-08-28 WO PCT/US2009/055376 patent/WO2010025374A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
DK2324120T3 (en) | 2016-05-02 |
CN102216464A (zh) | 2011-10-12 |
JP5656836B2 (ja) | 2015-01-21 |
WO2010025374A2 (en) | 2010-03-04 |
WO2010025374A3 (en) | 2010-05-27 |
AU2009285590B2 (en) | 2015-02-05 |
AU2009285590A1 (en) | 2010-03-04 |
EP2324120A2 (en) | 2011-05-25 |
EP2324120B1 (en) | 2016-01-27 |
CA2734264A1 (en) | 2010-03-04 |
EP2324120A4 (en) | 2013-08-14 |
US8435758B2 (en) | 2013-05-07 |
JP2012501185A (ja) | 2012-01-19 |
US20100062502A1 (en) | 2010-03-11 |
CN102216464B (zh) | 2014-11-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |