MX341239B - Compuestos de 2,4-diamino-pirimidina y sus usos. - Google Patents

Compuestos de 2,4-diamino-pirimidina y sus usos.

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Publication number
MX341239B
MX341239B MX2011005027A MX2011005027A MX341239B MX 341239 B MX341239 B MX 341239B MX 2011005027 A MX2011005027 A MX 2011005027A MX 2011005027 A MX2011005027 A MX 2011005027A MX 341239 B MX341239 B MX 341239B
Authority
MX
Mexico
Prior art keywords
pyrimidinediamine compounds
ige
release
methods
compounds
Prior art date
Application number
MX2011005027A
Other languages
English (en)
Inventor
Li Hui
Singh Rajinder
Argade Ankush
G Payan Donald
Molineaux Susan
J Holland Sacha
Clough Jeffrey
Keim Holger
Bhamidipati Somasekhar
Sylvain Catherine
B Rossi Alexander
Original Assignee
Rigel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32996332&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX341239(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of MX341239B publication Critical patent/MX341239B/es

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

El presente invento provee compuestos de 2-4-diamino-pirimidina que inhiben las cascadas de señalización del receptor IgE y/o IgG que conducen a la liberación de mediadores químicos, intermediarios y métodos de sintetización de compuestos y métodos de uso de los compuestos en una variedad de contextos, que incluyen el tratamiento y prevención de enfermedades caracterizadas por o asociadas con la liberación de mediadores químicos vía degranulación y otros procesos efectuados mediante activación de las cascadas de señalización del receptor IgE y/o IgG.
MX2011005027A 2002-02-01 2004-07-30 Compuestos de 2,4-diamino-pirimidina y sus usos. MX341239B (es)

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US35326702P 2002-02-01 2002-02-01
US39967302P 2002-07-29 2002-07-29
US43427702P 2002-12-17 2002-12-17
US11/539,029 US7642351B2 (en) 2002-02-01 2006-10-05 2,4-Pyrimidinediamine compounds and their uses

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