|
US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
|
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
|
SE378109B
(OSRAM)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
|
SE378110B
(OSRAM)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
DK149080C
(da)
|
1980-06-06 |
1986-07-28 |
Sankyo Co |
Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
|
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
|
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
|
US5041653A
(en)
|
1985-05-03 |
1991-08-20 |
Sri International |
Substituted benzamide radiosensitizers
|
|
US5032617A
(en)
|
1985-05-03 |
1991-07-16 |
Sri International |
Substituted benzamide radiosensitizers
|
|
US5215738A
(en)
|
1985-05-03 |
1993-06-01 |
Sri International |
Benzamide and nicotinamide radiosensitizers
|
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
|
US4885314A
(en)
|
1987-06-29 |
1989-12-05 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US4782084A
(en)
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
|
EP0360390A1
(en)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactam derivatives
|
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
|
MX18467A
(es)
|
1988-11-23 |
1993-07-01 |
Pfizer |
Agentes terapeuticos de quinuclidinas
|
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
PH27357A
(en)
|
1989-09-22 |
1993-06-21 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives and pharmaceutical compositions comprising the same
|
|
FI97540C
(fi)
|
1989-11-06 |
1997-01-10 |
Sanofi Sa |
Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
|
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
WO1991009844A1
(en)
|
1990-01-04 |
1991-07-11 |
Pfizer Inc. |
Substance p antagonists
|
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
|
EP0515681A4
(en)
|
1990-02-15 |
1993-12-29 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compound
|
|
US5420245A
(en)
|
1990-04-18 |
1995-05-30 |
Board Of Regents, The University Of Texas |
Tetrapeptide-based inhibitors of farnesyl transferase
|
|
GB9011833D0
(en)
|
1990-05-25 |
1990-07-18 |
Collins Mary K L |
Inhibition of viral infection
|
|
US5451586A
(en)
|
1990-06-01 |
1995-09-19 |
Pfizer Inc. |
3-amino-2-aryl quinuclidines
|
|
US5422354A
(en)
|
1990-07-23 |
1995-06-06 |
Pfizer Inc |
Quinuclidine derivatives
|
|
ES2071334T3
(es)
|
1990-09-28 |
1995-06-16 |
Pfizer |
Analogos de anillos fusionados de nitrogeno conteniendo heterociclos no aromaticos.
|
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
DK0498069T3
(da)
|
1990-12-21 |
1995-12-04 |
Fujisawa Pharmaceutical Co |
Ny anvendelse af peptidderivat
|
|
FI933167A7
(fi)
|
1991-01-10 |
1993-07-09 |
Pfizer |
N-alkyylikinuklidiniumsuolat aineen P antagonisteina
|
|
EP0499313B1
(en)
|
1991-02-11 |
1997-06-11 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
DE69200921T2
(de)
|
1991-03-01 |
1995-05-04 |
Pfizer |
1-azabicyclo[3.2.2]nonan-3-aminderivate.
|
|
US5747469A
(en)
|
1991-03-06 |
1998-05-05 |
Board Of Regents, The University Of Texas System |
Methods and compositions comprising DNA damaging agents and p53
|
|
PL169993B1
(pl)
|
1991-03-26 |
1996-09-30 |
Pfizer |
Sposób wytwarzania podstawionych piperydyn PL PL PL PL
|
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
|
US5292726A
(en)
|
1991-05-22 |
1994-03-08 |
Merck & Co., Inc. |
N,N-diacylpiperazines
|
|
RU2092486C1
(ru)
|
1991-05-22 |
1997-10-10 |
Пфайзер Инк. |
Замещенные 3-аминохинуклидины
|
|
DE122006000066I2
(de)
|
1991-05-31 |
2007-12-06 |
Pfizer |
Chinuclidinderivate
|
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
BR9206161A
(pt)
|
1991-06-20 |
1995-10-31 |
Pfizer |
Derivados fluoroalcoxibenzilamino de heterociclos contendo nitrogénio
|
|
TW202432B
(OSRAM)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
DE69208088T2
(de)
|
1991-07-05 |
1996-11-14 |
Merck Sharp & Dohme |
Aromatische verbindungen, diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische anwendung
|
|
EP0536817A1
(en)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds as tachykinin antagonists
|
|
WO1993001169A2
(en)
|
1991-07-05 |
1993-01-21 |
Merck Sharp & Dohme Limited |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
JPH06509090A
(ja)
|
1991-07-10 |
1994-10-13 |
メルク シヤープ エンド ドーム リミテツド |
芳香族化合物、それらを含む組成物、及び治療におけるそれらの使用
|
|
WO1993001159A1
(en)
|
1991-07-10 |
1993-01-21 |
Merck Sharp & Dohme Limited |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
|
WO1993004040A1
(en)
|
1991-08-20 |
1993-03-04 |
Merck Sharp & Dohme Limited |
Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
PT533280E
(pt)
|
1991-09-20 |
2001-01-31 |
Glaxo Group Ltd |
Novas utilizacoes medicas para antagonistas de taquiquinina
|
|
CZ59394A3
(en)
|
1991-09-26 |
1994-11-16 |
Pfizer |
Condensed tricyclic heterocycles containing nitrogen as antagonists of p substance receptor, process of their preparation, intermediates, pharmaceutical preparations in which they are comprised and use
|
|
US5753674A
(en)
|
1991-10-22 |
1998-05-19 |
Octamer, Inc. |
Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents, anti-retroviral agents and anti-tumor agents
|
|
WO1993009116A1
(fr)
|
1991-11-07 |
1993-05-13 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Compose a base de quinuclidine et utilisation dudit compose en medecine
|
|
DK0613458T3
(da)
|
1991-11-12 |
1998-02-09 |
Pfizer |
Acykliske ethylendiaminderivater som substans P receptorantagonister
|
|
CA2083891A1
(en)
|
1991-12-03 |
1993-06-04 |
Angus Murray Macleod |
Heterocyclic compounds, compositions containing them and their use in therapy
|
|
HU9203780D0
(en)
|
1991-12-12 |
1993-03-29 |
Sandoz Ag |
Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
|
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
CA2133077A1
(en)
|
1992-04-15 |
1993-10-28 |
Raymond Baker |
Azacyclic compounds
|
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
|
CA2134964C
(en)
|
1992-05-18 |
1997-12-30 |
Manoj C. Desai |
Bridged aza-bicyclic derivatives as substance p antagonists
|
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2099233A1
(en)
|
1992-06-29 |
1993-12-30 |
Conrad P. Dorn |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
US5637699A
(en)
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
|
US5612336A
(en)
|
1992-07-13 |
1997-03-18 |
Merck, Sharp & Dohme Ltd. |
Heterocyclic amide derivatives as tachykinin antagonists
|
|
EP0786522A2
(en)
|
1992-07-17 |
1997-07-30 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecules for treatment of stenotic conditions
|
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
|
AU675447B2
(en)
|
1992-07-28 |
1997-02-06 |
Merck Sharp & Dohme Limited |
Carboxamidomethyl piperidine and analogues
|
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
|
AU4718093A
(en)
|
1992-07-31 |
1994-03-03 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
|
CA2141051A1
(en)
|
1992-08-04 |
1994-02-17 |
Terry J. Rosen |
Substituted nitrogen-containing heterocycles
|
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
DK0655055T3
(da)
|
1992-08-13 |
2001-01-02 |
Warner Lambert Co |
Tachykininantagonister
|
|
EP1114823A3
(en)
|
1992-08-19 |
2001-07-18 |
Pfizer Inc. |
Substituted benzylamino nitrogen containing non-aromatic heterocycles
|
|
US5387595A
(en)
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
|
NO179904C
(no)
|
1992-09-04 |
1997-01-08 |
Takeda Chemical Industries Ltd |
Kondenserte heterocykliske forbindelser og deres anvendelse
|
|
AU4973693A
(en)
|
1992-09-10 |
1994-03-29 |
Merck Sharp & Dohme Limited |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
|
WO1994010165A1
(en)
|
1992-10-28 |
1994-05-11 |
Merck Sharp & Dohme Limited |
4-arylmethyloxymethyl piperidines as tachykinin antagonists
|
|
US5554627A
(en)
|
1992-10-30 |
1996-09-10 |
Merck, Sharp & Dohme Ltd. |
Tachykinin antagonists
|
|
ES2096312T3
(es)
|
1992-11-12 |
1997-03-01 |
Pfizer |
Derivado de quinuclidina como antagonista de la sustancia p.
|
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
|
PT675886E
(pt)
|
1992-12-10 |
2000-12-29 |
Pfizer |
Heterociclos nao aromaticos com substituintes aminometileno e sua utilizacao como antagonistas da substancia p
|
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
|
JPH08504435A
(ja)
|
1992-12-14 |
1996-05-14 |
メルク シヤープ エンド ドーム リミテツド |
タキキニン受容体拮抗剤としての４−アミノメチル／チオメチル／スルホニルメチル−４−フェニルピペリジン
|
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2111902A1
(en)
|
1992-12-21 |
1994-06-22 |
Jack Beuford Campbell |
Antitumor compositions and methods of treatment
|
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2152792C
(en)
|
1993-01-15 |
2000-02-15 |
Stephen R. Bertenshaw |
Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
|
EP0610793A1
(en)
|
1993-02-08 |
1994-08-17 |
Takeda Chemical Industries, Ltd. |
Tetracyclic morpholine derivatives and their use or analgesics
|
|
JPH08506823A
(ja)
|
1993-02-18 |
1996-07-23 |
メルク シヤープ エンド ドーム リミテツド |
アザ環式化合物、該化合物を含む組成物及びタキキニン拮抗剤としての該化合物の使用
|
|
AU6140694A
(en)
|
1993-02-22 |
1994-09-14 |
Merck Sharp & Dohme Limited |
Aromatic compounds, compositions containing them and their use in therapy
|
|
WO1994019357A1
(en)
|
1993-02-23 |
1994-09-01 |
Merrell Dow Pharmaceuticals Inc. |
Farnesyl:protein transferase inhibitors as anticancer agents
|
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
|
US5688806A
(en)
|
1993-03-04 |
1997-11-18 |
Pfizer Inc. |
Spiroazacyclic derivatives as substance P antagonists
|
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
|
CA2118985A1
(en)
|
1993-04-02 |
1994-10-03 |
Dinesh V. Patel |
Heterocyclic inhibitors of farnesyl protein transferase
|
|
US5496833A
(en)
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
|
EP0696280B1
(en)
|
1993-05-06 |
1997-09-24 |
Merrell Pharmaceuticals Inc. |
Substituted pyrrolidin-3-yl-alkyl-piperidines useful as tachykinin antagonists
|
|
WO1994026723A2
(en)
|
1993-05-14 |
1994-11-24 |
Genentech, Inc. |
ras FARNESYL TRANSFERASE INHIBITORS
|
|
US5602098A
(en)
|
1993-05-18 |
1997-02-11 |
University Of Pittsburgh |
Inhibition of farnesyltransferase
|
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
|
AU680020B2
(en)
|
1993-06-07 |
1997-07-17 |
Merck & Co., Inc. |
Spiro-substituted azacycles as neurokinin antagonists
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
GB9602877D0
(en)
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
|
EP0634402A1
(en)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinone derivatives, their production and use
|
|
ES2121213T3
(es)
|
1993-07-15 |
1998-11-16 |
Pfizer |
Benciloxiquinuclidinas como antagonistas de la sustancia p.
|
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP0719266A1
(en)
|
1993-09-17 |
1996-07-03 |
Pfizer Inc. |
Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds
|
|
DE69433744T2
(de)
|
1993-09-17 |
2004-10-14 |
Pfizer Inc. |
3-amino-5-carboxy-substituierte piperidine und 3-amino-4-carboxy-substituierte pyrrolidine als tachykinin-antagonisten
|
|
WO1995008542A1
(en)
|
1993-09-22 |
1995-03-30 |
Kyowa Hakko Kogyo Co., Ltd. |
Farnesyltransferase inhibitor
|
|
IS4208A
(is)
|
1993-09-22 |
1995-03-23 |
Glaxo Group Limited |
3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
|
|
US5721236A
(en)
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
ES2164717T3
(es)
|
1993-10-15 |
2002-03-01 |
Schering Corp |
Compuestos triciclicos de sulfonamida utiles para inhibir la funcion de la proteina-g y para el tratamiento de enfermedades proliferativas.
|
|
US5719148A
(en)
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
ATE210652T1
(de)
|
1993-10-15 |
2001-12-15 |
Schering Corp |
Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und für die behandlung von proliferativen erkrankungen
|
|
IL111235A
(en)
|
1993-10-15 |
2001-03-19 |
Schering Plough Corp |
Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
|
|
US5661152A
(en)
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
KR100378615B1
(ko)
|
1993-10-25 |
2003-10-10 |
파크데이비스앤드캄파니 |
단백질:파르네실트랜스퍼라제의치환된테트라및펜타펩티드억제제
|
|
AU7947594A
(en)
|
1993-10-27 |
1995-05-22 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
|
WO1995012572A1
(en)
|
1993-11-04 |
1995-05-11 |
Abbott Laboratories |
Cyclobutane derivatives as inhibitors of squalene synthetase and protein farnesyltransferase
|
|
US5783593A
(en)
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
|
KR100362338B1
(ko)
|
1993-11-05 |
2003-04-08 |
워너-램버트 캄파니 |
단백질:파르네실트랜스퍼라아제의치환디-및트리펩티드억제제
|
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
|
US5484799A
(en)
|
1993-12-09 |
1996-01-16 |
Abbott Laboratories |
Antifungal dorrigocin derivatives
|
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
|
JPH09506898A
(ja)
|
1993-12-21 |
1997-07-08 |
イーライ・リリー・アンド・カンパニー |
非ペプチドタキキニン受容体アンタゴニスト
|
|
KR100286412B1
(ko)
|
1993-12-29 |
2001-04-16 |
더블유. 지. 콜 |
치환된 모르폴린 유도체, 이의 제조방법 및 이를 포함하는 약제학적 조성물
|
|
DE69416869T2
(de)
|
1993-12-29 |
1999-07-01 |
Pfizer Inc., New York, N.Y. |
Diazabicyclische neurokinin antagonisten
|
|
JPH09507500A
(ja)
|
1994-01-13 |
1997-07-29 |
メルク シヤープ エンド ドーム リミテツド |
ｇｅｍ二置換アザシクロ系のタキキニン拮抗薬
|
|
WO1995020575A1
(en)
|
1994-01-28 |
1995-08-03 |
Merck Sharp & Dohme Limited |
Aralkylamino substituted azacyclic therapeutic agents
|
|
US5393790A
(en)
|
1994-02-10 |
1995-02-28 |
G.D. Searle & Co. |
Substituted spiro compounds for the treatment of inflammation
|
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
|
IL112778A0
(en)
|
1994-03-04 |
1995-05-26 |
Merck & Co Inc |
Substituted heterocycles, their preparation and pharmaceutical compositions containing them
|
|
WO1995024612A1
(de)
|
1994-03-07 |
1995-09-14 |
International Business Machines Corporation |
Verfahren und vorrichtung zur schnellen interpolation von zwischenwerten aus periodischen phasenverschobenen signalen und zur erkennung von defekten in einem drehkörper
|
|
GB9404485D0
(en)
|
1994-03-09 |
1994-04-20 |
Cancer Res Campaign Tech |
Benzamide analogues
|
|
FI963597L
(fi)
|
1994-03-15 |
1996-11-14 |
Eisai Co Ltd |
Isoprenyylitransferaasi-inhibiittoreita
|
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
|
HUT72440A
(en)
|
1994-03-31 |
1996-04-29 |
Bristol Myers Squibb Co |
Imidazole-containing inhibitors of farnesyl protein transferase and pharmaceutical compositions containing them
|
|
US5523430A
(en)
|
1994-04-14 |
1996-06-04 |
Bristol-Myers Squibb Company |
Protein farnesyl transferase inhibitors
|
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
PE27997A1
(es)
|
1994-04-29 |
1997-09-20 |
Lilly Co Eli |
Antagonistas de receptores de taquicininas
|
|
US5747491A
(en)
|
1994-05-05 |
1998-05-05 |
Merck Sharp & Dohme Ltd. |
Morpholine derivatives and their use as antagonists of tachikinins
|
|
JPH09512806A
(ja)
|
1994-05-07 |
1997-12-22 |
ベーリンガー インゲルハイム コマンディトゲゼルシャフト |
新規なアミノ酸誘導体、その製造方法及びこれらの化合物を含む医薬組成物（ｉｉ）
|
|
US5510510A
(en)
|
1994-05-10 |
1996-04-23 |
Bristol-Meyers Squibb Company |
Inhibitors of farnesyl protein transferase
|
|
US5563255A
(en)
|
1994-05-31 |
1996-10-08 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of raf gene expression
|
|
JPH10501228A
(ja)
|
1994-06-06 |
1998-02-03 |
ワーナー−ランバート・コンパニー |
タキキニン（ｎｋ▲下１▼）受容体アンタゴニスト
|
|
EP0686629A3
(en)
|
1994-06-10 |
1999-02-10 |
Eli Lilly And Company |
Cyclohexyl tachykinine receptor antagonists
|
|
CN1150419A
(zh)
|
1994-06-10 |
1997-05-21 |
罗纳-布朗克罗莱尔股份有限公司 |
新的法呢基转移酶抑制剂、其制法及其药物组合物
|
|
US5571792A
(en)
|
1994-06-30 |
1996-11-05 |
Warner-Lambert Company |
Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
|
|
CZ288434B6
(en)
|
1994-07-12 |
2001-06-13 |
Lilly Co Eli |
Dihydrochloride trihydrate of (R)-3-(1H-indol-3-yl)-1-[N-(2-methoxybenzyl)acetylamino]-2-[N-/2-(4-piperid-1-yl)piperid-1-yl)acetyl/-amino]propane, pharmaceutical preparation in which it is comprised and use thereof
|
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
|
WO1996005529A1
(en)
|
1994-08-09 |
1996-02-22 |
Micron Optics, Inc. |
Temperature compensated fiber fabry-perot filters
|
|
CA2155448A1
(en)
|
1994-08-11 |
1996-02-12 |
Katerina Leftheris |
Inhibitors of farnesyl protein transferase
|
|
WO1996005168A1
(en)
|
1994-08-11 |
1996-02-22 |
Banyu Pharmaceutical Co., Ltd. |
Substituted amide derivative
|
|
WO1996005169A1
(en)
|
1994-08-12 |
1996-02-22 |
Banyu Pharmaceutical Co., Ltd. |
N,n-disubstituted amic acid derivative
|
|
AU691958B2
(en)
|
1994-08-12 |
1998-05-28 |
Myriad Genetics, Inc. |
17q-linked breast and ovarian cancer susceptibility gene
|
|
PT705903E
(pt)
|
1994-08-12 |
2001-11-30 |
Myriad Genetics Inc |
Mutacoes no gene de susceptibilidade para o cancro da mama e do ovario ligado a 17q
|
|
WO1996005181A1
(en)
|
1994-08-15 |
1996-02-22 |
Merck Sharp & Dohme Limited |
Morpholine derivatives and their use as therapeutic agents
|
|
DE4429506B4
(de)
|
1994-08-19 |
2007-09-13 |
Degussa Gmbh |
Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe
|
|
DE4429653C2
(de)
|
1994-08-20 |
1997-04-03 |
Anton Dr More |
Konverter und Verfahren zum Frischen von Metallschmelzen insbesondere von Roheisen zu Stahl
|
|
WO1996006094A1
(en)
|
1994-08-25 |
1996-02-29 |
Merrell Pharmaceuticals Inc. |
Novel substituted piperidines useful for the treatment of allergic diseases
|
|
ATE158568T1
(de)
|
1994-08-29 |
1997-10-15 |
Akzo Nobel Nv |
Verfahren zur herstellung von quaternären diestern
|
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
|
CA2198382A1
(en)
|
1994-09-30 |
1996-04-11 |
Novartis Ag |
1-acyl-4-aliphatylaminopiperidine compounds
|
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
EP0709375B1
(en)
|
1994-10-25 |
2005-05-18 |
AstraZeneca AB |
Therapeutic heterocycles
|
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
|
WO1996016443A1
(en)
|
1994-11-22 |
1996-05-30 |
Philips Electronics N.V. |
Semiconductor device with a carrier body on which a substrate with a semiconductor element is fastened by means of a glue layer and on which a pattern of conductor tracks is fastened
|
|
EP0714891A1
(en)
|
1994-11-22 |
1996-06-05 |
Eli Lilly And Company |
Heterocyclic tachykinin receptor antagonists
|
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
CA2204144A1
(en)
|
1994-12-09 |
1996-06-13 |
Francis J. Tinney |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
|
IL116323A0
(en)
|
1994-12-13 |
1996-03-31 |
Sandoz Ag |
Tachykinin antagonists their preparation and pharmaceutical compositions containing them
|
|
US5589483A
(en)
|
1994-12-21 |
1996-12-31 |
Geron Corporation |
Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence
|
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO1996021701A2
(en)
|
1995-01-09 |
1996-07-18 |
Magla International Ltd. |
Wear resistant image printing on latex surfaces
|
|
ATE279406T1
(de)
|
1995-01-12 |
2004-10-15 |
Glaxo Group Ltd |
Piperidinderivate mit tachykinin-antagonistischer wirkung
|
|
AU4915796A
(en)
|
1995-01-12 |
1996-07-31 |
University Of Pittsburgh |
Inhibitors of prenyl transferases
|
|
FR2729390A1
(fr)
|
1995-01-18 |
1996-07-19 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
FR2730492B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2730491B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
TW394773B
(en)
|
1995-03-24 |
2000-06-21 |
Takeda Chemical Industries Ltd |
Cyclic compounds for antagonizing tachykinin receptor, substance p receptor and neurokinin a receptor, their production and pharmaceutical composition
|
|
US5684013A
(en)
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
US5700806A
(en)
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
|
US5712280A
(en)
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
US5891872A
(en)
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
|
CA2217351C
(en)
|
1995-04-07 |
2003-03-18 |
Schering Corporation |
Carbonyl-piperazinyl and piperidinyl compounds which inhibit farnesyl protein transferase
|
|
IL117798A
(en)
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
|
AU700693B2
(en)
|
1995-04-13 |
1999-01-14 |
Aventis Pharmaceuticals Inc. |
Novel substituted piperazine derivatives having tachykinin receptor antagonists activity
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
IL118101A0
(en)
|
1995-05-03 |
1996-09-12 |
Abbott Lab |
Inhibitors of farnesyltransferase
|
|
HUP9900822A3
(en)
|
1995-05-25 |
1999-11-29 |
Fujisawa Pharmaceutical Co |
Piperazine derivatives, process for producing them, pharmaceutical compositions containing them and method for treating tachykinin-mediated diseases
|
|
WO1997000252A1
(en)
|
1995-06-16 |
1997-01-03 |
Warner-Lambert Company |
Tricyclic inhibitors of protein farnesyltransferase
|
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6180647B1
(en)
|
1995-07-07 |
2001-01-30 |
Pfizer Inc. |
Substituted benzolactam compounds as substance P antagonists
|
|
FR2736641B1
(fr)
|
1995-07-10 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
AT402617B
(de)
|
1995-07-11 |
1997-07-25 |
Datacon Schweitzer & Zeindl Gm |
Anlage zum automatisierten, hermetischen anlage zum automatisierten, hermetischen verschliessen von gehäusen verschliessen von gehäusen
|
|
FR2736638B1
(fr)
|
1995-07-12 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
CH690163A5
(fr)
|
1995-07-28 |
2000-05-31 |
Symphar Sa |
Dérivés gem-diphosphonates substitués utiles en tant qu'agents anti-cancers.
|
|
PL324869A1
(en)
|
1995-08-02 |
1998-06-22 |
Univ Newcastle Ventures Ltd |
Benzimidazole compounds
|
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
JP2002534955A
(ja)
|
1995-10-18 |
2002-10-15 |
メルク エンド カンパニー インコーポレーテッド |
シクロペンチルタキキニン受容体アンタゴニスト
|
|
CA2235986C
(en)
|
1995-11-06 |
2006-09-12 |
University Of Pittsburgh |
Inhibitors of protein isoprenyl transferases
|
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6288237B1
(en)
|
1995-11-17 |
2001-09-11 |
Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) |
Epothilons C and D, preparation and compositions
|
|
EP0862435A4
(en)
|
1995-11-22 |
1999-02-03 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase
|
|
US6060469A
(en)
|
1995-11-23 |
2000-05-09 |
Merck Sharp & Dohme Ltd. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
|
HU224225B1
(hu)
|
1995-12-01 |
2005-06-28 |
Sankyo Co. Ltd. |
Tachikinin receptor antagonista hatású heterociklusos vegyületek, ezek előállítási eljárása és alkalmazásuk gyógyszerkészítmények előállítására
|
|
EE03484B1
(et)
|
1995-12-08 |
2001-08-15 |
Janssen Pharmaceutica N.V. |
Farnesüülproteiintransferaasi inhibeerivad (5-imidasolüül)metüül-2-kinolinooni derivaadid ja nende kasutamine
|
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1380581A1
(en)
|
1995-12-22 |
2004-01-14 |
Schering Corporation |
Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
WO1997026246A1
(en)
|
1996-01-16 |
1997-07-24 |
Warner-Lambert Company |
Substituted histidine inhibitors of protein farnesyltransferase
|
|
US6673927B2
(en)
|
1996-02-16 |
2004-01-06 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Farnesyl transferase inhibitors
|
|
CA2249601A1
(en)
|
1996-04-03 |
1997-10-23 |
Thorsten E. Fisher |
Inhibitors of farnesyl-protein transferase
|
|
BR9708574A
(pt)
|
1996-04-12 |
1999-08-03 |
Searle & Co |
Derivados benzeno sulfonamida substituídos como pródrogas de inibidores cox-2
|
|
EP0938494A1
(en)
|
1996-05-22 |
1999-09-01 |
Warner-Lambert Company |
Inhibitors of protein farnesyl transferase
|
|
EP0918771A4
(en)
|
1996-07-15 |
2001-02-07 |
Bristol Myers Squibb Co |
THIADIOXOBENZODIAZEPINES FOR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS
|
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
|
EP2298350A3
(en)
|
1996-07-26 |
2011-06-08 |
Susan P. Perrine |
Composition comprising an inducing agent and an anti-viral agent for the treatment of viral disorders
|
|
US6242469B1
(en)
|
1996-12-03 |
2001-06-05 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
CA2276150A1
(en)
|
1996-12-30 |
1998-07-09 |
Steven D. Young |
Inhibitors of farnesyl-protein transferase
|
|
JP2002511054A
(ja)
|
1996-12-30 |
2002-04-09 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル蛋白トランスフェラーゼ阻害薬
|
|
AU9297998A
(en)
|
1998-05-15 |
1999-12-06 |
Guilford Pharmaceuticals Inc. |
Carboxamide compounds, compositions, and methods for inhibiting parp activity
|
|
PL198180B1
(pl)
|
1998-10-30 |
2008-06-30 |
Lonza Ag |
Sposób wytwarzania 4-[(2',5'-diamino-6'-chlorowcopirymidyn-4'-ylo)amino]-cyklopent-2-enylometanoli
|
|
CZ20011546A3
(cs)
|
1998-11-03 |
2001-08-15 |
Basf Aktiengesellschaft |
Derivát substituovaného 2-fenylbenzimidazolu, způsob jeho přípravy a jeho použití
|
|
HRP20010451A2
(en)
|
1998-11-17 |
2003-04-30 |
Basf Ag |
2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof
|
|
CN1184208C
(zh)
|
1998-11-27 |
2005-01-12 |
巴斯福股份公司 |
取代的苯并咪唑及其制备和用途
|
|
CA2361553A1
(en)
|
1999-01-29 |
2000-08-03 |
Zhenping Zhu |
Antibodies specific to kdr and uses thereof
|
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
|
AU4972900A
(en)
|
1999-04-08 |
2000-11-14 |
Arch Development Corporation |
Use of anti-vegf antibody to enhance radiation in cancer therapy
|
|
DE19918211A1
(de)
|
1999-04-22 |
2000-10-26 |
Basf Ag |
Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung
|
|
DE19920936A1
(de)
|
1999-05-07 |
2000-11-09 |
Basf Ag |
Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung
|
|
AU7314200A
(en)
|
1999-09-17 |
2001-04-24 |
Yamanouchi Pharmaceutical Co., Ltd. |
Benzimidazole derivatives
|
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
|
EP1686120A3
(en)
|
1999-10-27 |
2007-05-30 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
|
ES2290115T3
(es)
|
2000-02-01 |
2008-02-16 |
ABBOTT GMBH & CO. KG |
Compuestos heterociclicos y su aplicacion como inhibidores de parp.
|
|
DE10022925A1
(de)
|
2000-05-11 |
2001-11-15 |
Basf Ag |
Substituierte Indole als PARP-Inhibitoren
|
|
US6992082B2
(en)
|
2001-01-19 |
2006-01-31 |
Cytokinetics, Inc. |
Phenothiazine kinesin inhibitors
|
|
WO2002056880A1
(en)
|
2001-01-19 |
2002-07-25 |
Cytokinetics, Inc. |
Triphenylmethane kinesin inhibitors
|
|
JPWO2002068407A1
(ja)
|
2001-02-28 |
2004-06-24 |
山之内製薬株式会社 |
ベンゾイミダゾール化合物
|
|
ATE400274T1
(de)
|
2001-04-10 |
2008-07-15 |
Merck & Co Inc |
Hemmstoffe der akt aktivität
|
|
AU2002251266A1
(en)
|
2001-04-10 |
2002-10-28 |
Merck Sharp And Dohme Limited |
Inhibitors of akt activity
|
|
WO2002083140A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2003007959A1
(en)
|
2001-07-16 |
2003-01-30 |
Fujisawa Pharmaceutical Co., Ltd. |
Quinoxaline derivatives which have parp inhibitory action
|
|
WO2003013526A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co. Inc. |
Anticoagulant compounds
|
|
US7060705B2
(en)
|
2001-11-07 |
2006-06-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
EP1481077B1
(en)
|
2001-12-06 |
2009-11-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US7378411B2
(en)
|
2001-12-06 |
2008-05-27 |
Merck & Co., Inc. |
Substituted thienopyrimidinones as a mitotic kinesin inhibitor
|
|
CA2467916A1
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US7244723B2
(en)
|
2001-12-06 |
2007-07-17 |
Merck & Co., Inc. |
Substituted furopyrimidinones as a mitotic kinesin inhibitors
|
|
JP4391825B2
(ja)
|
2001-12-06 |
2009-12-24 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
DK1461359T3
(da)
|
2002-01-18 |
2007-07-09 |
Pf Medicament |
Hidtil ukendte anti-IGF-IR-antistoffer og anvendelser deraf
|
|
JPWO2003062234A1
(ja)
|
2002-01-23 |
2005-05-19 |
山之内製薬株式会社 |
キノキサリン化合物
|
|
CA2478068C
(en)
|
2002-03-08 |
2011-02-08 |
Merck & Co., Inc. |
Dihydropyrazole compounds useful for treating or preventing cancer
|
|
WO2003086394A1
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
US7273869B2
(en)
|
2002-04-08 |
2007-09-25 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
WO2003086279A2
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2003086403A1
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
AU2003231799A1
(en)
|
2002-05-23 |
2003-12-12 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
CA2485343A1
(en)
|
2002-05-23 |
2004-05-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US20040034078A1
(en)
|
2002-06-14 |
2004-02-19 |
Agouron Pharmaceuticals, Inc. |
Benzimidazole inhibitors of poly(ADP-ribosyl) polymerase
|
|
JP4463679B2
(ja)
|
2002-06-14 |
2010-05-19 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
JP4377323B2
(ja)
|
2002-06-14 |
2009-12-02 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
AU2003252315A1
(en)
|
2002-08-09 |
2004-02-25 |
Kyorin Pharmaceutical Co., Ltd. |
4-substituted-quinoline-8-carboxylic amide derivatives and pharmacologically acceptable addition salts thereof
|
|
EP1556052A4
(en)
|
2002-10-18 |
2006-11-02 |
Merck & Co Inc |
MITOTIC KINESINE HEMMER
|
|
EP1581497A4
(en)
|
2002-12-20 |
2009-03-18 |
Merck & Co Inc |
INHIBITORS OF MITOTIC KINESINE
|
|
WO2004058700A2
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
AU2003296405A1
(en)
*
|
2003-01-06 |
2004-08-10 |
Eli Lilly And Company |
Fused heterocyclic derivatives as ppar modulators
|
|
WO2004087050A2
(en)
|
2003-03-28 |
2004-10-14 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
HU0301154D0
(en)
|
2003-04-28 |
2003-07-28 |
Hideg Kalman Dr |
Pharmaceutical composition
|
|
EP1706386A1
(en)
|
2003-12-22 |
2006-10-04 |
Eli Lilly And Company |
Bicyclic derivatives as ppar modulators
|
|
AU2005216978A1
(en)
|
2004-02-26 |
2005-09-09 |
Inotek Pharmaceuticals Corporation |
Isoquinoline derivatives and methods of use thereof
|
|
CA2569826C
(en)
*
|
2004-06-30 |
2013-07-16 |
Janssen Pharmaceutica N.V. |
Substituted 2-alkyl quinazolinone derivatives as parp inhibitors
|
|
AU2005276229A1
(en)
|
2004-08-26 |
2006-03-02 |
Kudos Pharmaceuticals Limited |
4-heteroarylmethyl substituted phthalazinone derivatives
|
|
MX2007003311A
(es)
|
2004-09-22 |
2007-05-16 |
Pfizer |
Procedimiento para preparar inhibidores de poli (adp-ribosa) polimerasas.
|
|
TWI375673B
(en)
|
2005-04-11 |
2012-11-01 |
Abbott Lab |
1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
|
|
WO2006110683A1
(en)
|
2005-04-11 |
2006-10-19 |
Abbott Laboratories |
2-substituted-1h-benzimidazole-4-carboxamides are parp inhibitors
|
|
ES2378692T3
(es)
*
|
2005-09-29 |
2012-04-17 |
Abbott Laboratories |
Las 1H-benzimidazol-4-carboxamidas sustituidas con fenilo en la posición 2 son potentes inhibidores de PARP
|
|
TW200736229A
(en)
|
2005-11-15 |
2007-10-01 |
Abbott Lab |
Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
|
|
JP4611441B2
(ja)
*
|
2006-04-03 |
2011-01-12 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）阻害剤としてのアミド置換インダゾール及びベンゾトリアゾール誘導体
|
|
WO2007131016A2
(en)
|
2006-05-02 |
2007-11-15 |
Abbott Laboratories |
Substituted 1h-benzimidazole-4-carboxamides are potent parp inhibitors
|
|
US20090062268A1
(en)
*
|
2007-08-27 |
2009-03-05 |
Lead Therapeutics, Inc. |
Novel inhibitors of poly(adp-ribose)polymerase (parp)
|
|
JP2011511078A
(ja)
*
|
2008-02-06 |
2011-04-07 |
レアド トヘラペウトイクス，インコーポレーテッド |
ポリ（ａｄｐリボース）ポリメラーゼ（ｐａｒｐ）のベンズオキサゾールカルボキサミド阻害剤
|