GB0700432D0 - Therapeutic compounds - Google Patents

Therapeutic compounds

Info

Publication number
GB0700432D0
GB0700432D0 GBGB0700432.8A GB0700432A GB0700432D0 GB 0700432 D0 GB0700432 D0 GB 0700432D0 GB 0700432 A GB0700432 A GB 0700432A GB 0700432 D0 GB0700432 D0 GB 0700432D0
Authority
GB
United Kingdom
Prior art keywords
diseases
cancer
treatment
cardiovascular diseases
therapeutic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0700432.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Original Assignee
Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37809722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB0700432(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Istituto di Ricerche di Biologia Molecolare P Angeletti SpA filed Critical Istituto di Ricerche di Biologia Molecolare P Angeletti SpA
Priority to GBGB0700432.8A priority Critical patent/GB0700432D0/en
Publication of GB0700432D0 publication Critical patent/GB0700432D0/en
Priority to CA2647545A priority patent/CA2647545C/en
Priority to JP2009503667A priority patent/JP4611441B2/en
Priority to EP07733600.6A priority patent/EP2007733B1/en
Priority to US12/225,857 priority patent/US20090275619A1/en
Priority to AU2007232297A priority patent/AU2007232297B2/en
Priority to PCT/GB2007/050177 priority patent/WO2007113596A1/en
Priority to CN200780012001.6A priority patent/CN101415686B/en
Priority to DK11157369.7T priority patent/DK2336120T3/en
Priority to PL11157369T priority patent/PL2336120T3/en
Priority to RS20110236A priority patent/RS51780B/en
Priority to ES08702101T priority patent/ES2362214T3/en
Priority to PCT/GB2008/050018 priority patent/WO2008084261A1/en
Priority to CN2008800019265A priority patent/CN101578279B/en
Priority to HUE14176452 priority patent/HUE044513T2/en
Priority to BRPI0806245-5A priority patent/BRPI0806245B1/en
Priority to EP19164594.4A priority patent/EP3536690A1/en
Priority to RS20190600A priority patent/RS58936B1/en
Priority to MEP-2019-147A priority patent/ME03481B/en
Priority to LTEP14176452.2T priority patent/LT2805945T/en
Priority to NZ578256A priority patent/NZ578256A/en
Priority to SI200832067T priority patent/SI2805945T1/en
Priority to US12/006,993 priority patent/US8071623B2/en
Priority to UAA200908335A priority patent/UA97658C2/en
Priority to EP08702101A priority patent/EP2109608B1/en
Priority to CA2674436A priority patent/CA2674436C/en
Priority to KR1020097014520A priority patent/KR101591656B1/en
Priority to GEAP200811413A priority patent/GEP20115337B/en
Priority to PL14176452T priority patent/PL2805945T3/en
Priority to EA200970674A priority patent/EA016079B1/en
Priority to EP11157369.7A priority patent/EP2336120B1/en
Priority to ES14176452T priority patent/ES2728199T3/en
Priority to CL200800046A priority patent/CL2008000046A1/en
Priority to ES11157369.7T priority patent/ES2509115T3/en
Priority to PT111573697T priority patent/PT2336120E/en
Priority to SI200831266T priority patent/SI2336120T1/en
Priority to DK08702101.0T priority patent/DK2109608T3/en
Priority to PT14176452T priority patent/PT2805945T/en
Priority to EP14176452.2A priority patent/EP2805945B1/en
Priority to AU2008204380A priority patent/AU2008204380B2/en
Priority to JP2009545240A priority patent/JP4611444B2/en
Priority to PT08702101T priority patent/PT2109608E/en
Priority to MYPI20092876A priority patent/MY147789A/en
Priority to MX2009007200A priority patent/MX2009007200A/en
Priority to AT08702101T priority patent/ATE502933T1/en
Priority to PL08702101T priority patent/PL2109608T3/en
Priority to ARP080100061A priority patent/AR064777A1/en
Priority to PE2008000097A priority patent/PE20081558A1/en
Priority to SI200830240T priority patent/SI2109608T1/en
Priority to TW097100730A priority patent/TWI528961B/en
Priority to DK14176452.2T priority patent/DK2805945T3/en
Priority to DE602008005711T priority patent/DE602008005711D1/en
Priority to ZA200903898A priority patent/ZA200903898B/en
Priority to IL199264A priority patent/IL199264A/en
Priority to DO2009000170A priority patent/DOP2009000170A/en
Priority to CR10910A priority patent/CR10910A/en
Priority to SV2009003321A priority patent/SV2009003321A/en
Priority to CO09068415A priority patent/CO6210732A2/en
Priority to NI200900135A priority patent/NI200900135A/en
Priority to GT200900190A priority patent/GT200900190A/en
Priority to HN2009001260A priority patent/HN2009001260A/en
Priority to TNP2009000286A priority patent/TN2009000286A1/en
Priority to EC2009009484A priority patent/ECSP099484A/en
Priority to MA32111A priority patent/MA31554B1/en
Priority to HK11108534.3A priority patent/HK1154386A1/en
Priority to HK09110676.1A priority patent/HK1131137A1/en
Priority to US13/091,427 priority patent/US20110201657A1/en
Priority to HR20110447T priority patent/HRP20110447T1/en
Priority to CY20111100595T priority patent/CY1111584T1/en
Priority to NL300937C priority patent/NL300937I2/en
Priority to LTPA2018009C priority patent/LTC2109608I2/en
Priority to LU00072C priority patent/LUC00072I2/en
Priority to HUS1800022C priority patent/HUS1800022I1/en
Priority to NO2018016C priority patent/NO2018016I2/en
Priority to CY2018014C priority patent/CY2018014I1/en
Priority to HRP20190972TT priority patent/HRP20190972T1/en
Priority to CY20191100692T priority patent/CY1121751T1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts, stereoisomers or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory discuses, reperfusion injuries, ischemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes, neurodegenerative diseases, retroviral infection, retinal damage or skin senescence and UV-induced skin damage, and as chemo and/or radiosensitizers for cancer treatment.
GBGB0700432.8A 2006-04-03 2007-01-10 Therapeutic compounds Ceased GB0700432D0 (en)

Priority Applications (77)

Application Number Priority Date Filing Date Title
GBGB0700432.8A GB0700432D0 (en) 2007-01-10 2007-01-10 Therapeutic compounds
CA2647545A CA2647545C (en) 2006-04-03 2007-04-02 Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
JP2009503667A JP4611441B2 (en) 2006-04-03 2007-04-02 Amide-substituted indazole and benzotriazole derivatives as poly (ADP-ribose) polymerase (PARP) inhibitors
EP07733600.6A EP2007733B1 (en) 2006-04-03 2007-04-02 Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
US12/225,857 US20090275619A1 (en) 2006-04-03 2007-04-02 Amide Substituted Indazole and Benzotriazole Derivatives as Poly(ADP-Ribose)Polymerase (PARP) Inhibitors
AU2007232297A AU2007232297B2 (en) 2006-04-03 2007-04-02 Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors
PCT/GB2007/050177 WO2007113596A1 (en) 2006-04-03 2007-04-02 Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
CN200780012001.6A CN101415686B (en) 2006-04-03 2007-04-02 Amide substituted indazole and benzotriazole derivatives as poly(ADP-ribose)polymerase (PARP) inhibitors
DK11157369.7T DK2336120T3 (en) 2007-01-10 2008-01-08 COMBINATIONS CONTAINING AMID-SUBSTITUTED INDAZOLES AS POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS
PL11157369T PL2336120T3 (en) 2007-01-10 2008-01-08 Combinations containing amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
RS20110236A RS51780B (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
ES08702101T ES2362214T3 (en) 2007-01-10 2008-01-08 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP).
PCT/GB2008/050018 WO2008084261A1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
CN2008800019265A CN101578279B (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
HUE14176452 HUE044513T2 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
BRPI0806245-5A BRPI0806245B1 (en) 2007-01-10 2008-01-08 Compounds of formula i and their uses
EP19164594.4A EP3536690A1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
RS20190600A RS58936B1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
MEP-2019-147A ME03481B (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
LTEP14176452.2T LT2805945T (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
NZ578256A NZ578256A (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
SI200832067T SI2805945T1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
US12/006,993 US8071623B2 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase(PARP) inhibitors
UAA200908335A UA97658C2 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
EP08702101A EP2109608B1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
CA2674436A CA2674436C (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
KR1020097014520A KR101591656B1 (en) 2007-01-10 2008-01-08 - Amide substituted indazoles as polyADP-ribosepolymerasePARP inhibitors
GEAP200811413A GEP20115337B (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
PL14176452T PL2805945T3 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
EA200970674A EA016079B1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
EP11157369.7A EP2336120B1 (en) 2007-01-10 2008-01-08 Combinations containing amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
ES14176452T ES2728199T3 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly (ADP-ribose) polymerase (PARP) inhibitors
CL200800046A CL2008000046A1 (en) 2007-01-10 2008-01-08 COMPOUNDS DERIVED FROM 2- (4-PIPERIDIN-3-IL-FENIL) -7-AMIDO-2,7A-DIHIDRO-1H-INDAZOL; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS; AND ITS USE TO TREAT OR PREVENT CANCER, INFLAMMATORY DISEASES, REPERFUSION INJURIES, AFFECT
ES11157369.7T ES2509115T3 (en) 2007-01-10 2008-01-08 Combinations containing amide substituted indazoles as poly (ADP-ribose) polymerase (PARP) inhibitors
PT111573697T PT2336120E (en) 2007-01-10 2008-01-08 Combinations containing amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
SI200831266T SI2336120T1 (en) 2007-01-10 2008-01-08 Combinations containing amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
DK08702101.0T DK2109608T3 (en) 2007-01-10 2008-01-08 Amide-substituted indazoles as poly (ADP-ribose) polymerase (PARP) inhibitors
PT14176452T PT2805945T (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
EP14176452.2A EP2805945B1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
AU2008204380A AU2008204380B2 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
JP2009545240A JP4611444B2 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly (ADP-ribose) polymerase (PARP) inhibitors
PT08702101T PT2109608E (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
MYPI20092876A MY147789A (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
MX2009007200A MX2009007200A (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors.
AT08702101T ATE502933T1 (en) 2007-01-10 2008-01-08 AMIDE-SUBSTITUTED INDAZOLES AS POLY-(ADP-RIBOSE)-POLYMERASE (PARP) INHIBITORS
PL08702101T PL2109608T3 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
ARP080100061A AR064777A1 (en) 2007-01-10 2008-01-08 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP)
PE2008000097A PE20081558A1 (en) 2007-01-10 2008-01-08 INDAZOLES SUBSTITUTED WITH AMIDE AS POLY INHIBITORS (ADP-RIBOSE) POLYMERASE (PARP)
SI200830240T SI2109608T1 (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
TW097100730A TWI528961B (en) 2007-01-10 2008-01-08 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
DK14176452.2T DK2805945T3 (en) 2007-01-10 2008-01-08 AMID-SUBSTITUTED INDAZOLS AS POLY (ADP-RIBOSE) POLYMERASE (PARP) REQUESTS
DE602008005711T DE602008005711D1 (en) 2007-01-10 2008-01-08 AMIDSUBSTITUTED INDAZOLE AS A POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITOR
ZA200903898A ZA200903898B (en) 2007-01-10 2009-06-04 Amide substituted indazoles as poly (ADP-Ribose)polymerase (PARP) inhibitors
IL199264A IL199264A (en) 2007-01-10 2009-06-09 Amide substituted indazole compounds and use thereof for manufacture of medicaments for treatment of conditions that can be ameliorated by inhibition of poly (adp-ribose)polymerase (parp)
DO2009000170A DOP2009000170A (en) 2007-01-10 2009-07-02 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP)
CR10910A CR10910A (en) 2007-01-10 2009-07-02 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP)
SV2009003321A SV2009003321A (en) 2007-01-10 2009-07-02 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP)
CO09068415A CO6210732A2 (en) 2007-01-10 2009-07-02 INDAZOLS REPLACED WITH AMINA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP)
NI200900135A NI200900135A (en) 2007-01-10 2009-07-02 INDAZOLES SUBSTITUTED WITH AMIDE AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP).
GT200900190A GT200900190A (en) 2007-01-10 2009-07-02 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADP-RIBOSA) POLYMERASE (PARP)
HN2009001260A HN2009001260A (en) 2007-01-10 2009-07-02 INDAZOLS REPLACED WITH AMIDA AS POLY INHIBITORS (ADPRIBOSE) POLYMERASE (PARP)
TNP2009000286A TN2009000286A1 (en) 2007-01-10 2009-07-03 Amide substituted indazoles as poly (adp-ribose)polymerase (parp) inhibitors
EC2009009484A ECSP099484A (en) 2007-01-10 2009-07-03 INDAZOLS REPLACED WITH AMIDA AS INHIBITORS OF
MA32111A MA31554B1 (en) 2007-01-10 2009-07-20 AMIDE-SUBSTITUTED INDAZOLES AS INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE (PARP)
HK11108534.3A HK1154386A1 (en) 2007-01-10 2009-11-14 Combinations containing amide substituted indazoles as poly(adp- ribose)polymerase (parp) inhibitors (adp-)(parp)
HK09110676.1A HK1131137A1 (en) 2007-01-10 2009-11-14 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
US13/091,427 US20110201657A1 (en) 2006-04-03 2011-04-21 Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
HR20110447T HRP20110447T1 (en) 2007-01-10 2011-06-14 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
CY20111100595T CY1111584T1 (en) 2007-01-10 2011-06-22 AMIDO-SUBSTITUTED INDIAZOLS AS POLYMER (ADP-RIVOZIS) POLYMERIZATION INHIBITORS (PARP)
NL300937C NL300937I2 (en) 2007-01-10 2018-04-26 Niraparib, or a tautomer thereof, optionally in the form of a pharmaceutically acceptable salt, in particular the tosylate or a hydrate, more in particular the tosylate monohydrate
LTPA2018009C LTC2109608I2 (en) 2007-01-10 2018-04-30 The amide is replaced by indazoles as poly (ADP-ribose) polymerase (PARP) inhibitors
LU00072C LUC00072I2 (en) 2007-01-10 2018-05-03 Niraparib or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, in particular tosylate or a hydrate, particularly tosylate monohydrate
HUS1800022C HUS1800022I1 (en) 2007-01-10 2018-05-07 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
NO2018016C NO2018016I2 (en) 2007-01-10 2018-05-14 Niraparib or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof
CY2018014C CY2018014I1 (en) 2007-01-10 2018-05-15 AMIDO- SUBSTITUTED INDAZOLES AS INHIBITORS OF POLY (ADP-RIBOSE) POLYMERIZATION (PARP)
HRP20190972TT HRP20190972T1 (en) 2007-01-10 2019-05-28 Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
CY20191100692T CY1121751T1 (en) 2007-01-10 2019-07-02 AMIDO- SUBSTITUTED INDAZOLES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERIZATION (PARP)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0700432.8A GB0700432D0 (en) 2007-01-10 2007-01-10 Therapeutic compounds

Publications (1)

Publication Number Publication Date
GB0700432D0 true GB0700432D0 (en) 2007-02-21

Family

ID=37809722

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0700432.8A Ceased GB0700432D0 (en) 2006-04-03 2007-01-10 Therapeutic compounds

Country Status (21)

Country Link
CN (1) CN101578279B (en)
AT (1) ATE502933T1 (en)
CR (1) CR10910A (en)
DE (1) DE602008005711D1 (en)
DK (2) DK2109608T3 (en)
ES (3) ES2362214T3 (en)
GB (1) GB0700432D0 (en)
HN (1) HN2009001260A (en)
HU (1) HUE044513T2 (en)
LT (1) LT2805945T (en)
LU (1) LUC00072I2 (en)
ME (1) ME03481B (en)
MY (1) MY147789A (en)
NI (1) NI200900135A (en)
NZ (1) NZ578256A (en)
PE (1) PE20081558A1 (en)
PT (3) PT2805945T (en)
SI (2) SI2109608T1 (en)
TW (1) TWI528961B (en)
UA (1) UA97658C2 (en)
ZA (1) ZA200903898B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106496187A (en) * 2016-09-14 2017-03-15 陕西科技大学 A kind of synthetic method for preparing PARP inhibitor Niraparib
CN106432187A (en) * 2016-09-17 2017-02-22 青岛云天生物技术有限公司 Chiral resolution method of 2-[4-(-3-piperidyl)phenyl]-2H-indazole-7-formamide
CN106432188A (en) * 2016-09-17 2017-02-22 青岛辰达生物科技有限公司 Preparation method of anti-cancer drug 2-[4-((3S)-3-Piperidinyl) phenyl]-2H-Indazole-7-Formamide
CN106632244A (en) * 2016-09-30 2017-05-10 陕西科技大学 A novel synthetic method for preparing an anticancer medicine Niraparib
CN106467513A (en) * 2016-09-30 2017-03-01 陕西科技大学 A kind of synthetic method preparing Niraparib
CN108201537A (en) * 2016-12-16 2018-06-26 苏州苏融生物医药有限公司 A kind of Ni Lapani sustained and controlled release medicaments composition and application thereof
EA201992162A1 (en) * 2017-03-27 2020-02-28 Тесаро, Инк. COMPOSITIONS BASED ON NIRAPARIB
CN109081828B (en) 2017-06-14 2021-03-26 上海时莱生物技术有限公司 Poly (ADP-ribose) polymerase inhibitor, preparation method and application
CN111278433A (en) 2017-09-26 2020-06-12 特沙诺有限公司 Nilaparib formulations
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