EA201992430A1 - Комбинированная терапия рака предстательной железы - Google Patents

Комбинированная терапия рака предстательной железы

Info

Publication number
EA201992430A1
EA201992430A1 EA201992430A EA201992430A EA201992430A1 EA 201992430 A1 EA201992430 A1 EA 201992430A1 EA 201992430 A EA201992430 A EA 201992430A EA 201992430 A EA201992430 A EA 201992430A EA 201992430 A1 EA201992430 A1 EA 201992430A1
Authority
EA
Eurasian Patent Office
Prior art keywords
therapy
combined
effective amount
therapeutically effective
cancer
Prior art date
Application number
EA201992430A
Other languages
English (en)
Inventor
Маргарет К. Ю
Линда Энн Снайдер
Original Assignee
Янссен Фармацевтика Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62067858&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201992430(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Янссен Фармацевтика Нв filed Critical Янссен Фармацевтика Нв
Publication of EA201992430A1 publication Critical patent/EA201992430A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Предложены способы и композиции для лечения рака предстательной железы посредством введения нуждающемуся в этом пациенту терапевтически эффективного количества ингибитора PARP, например нирапариба; терапевтически эффективного количества ингибитора CYP17, например абиратерона ацетата; и терапевтически эффективного количества глюкокортикоида, например преднизона.
EA201992430A 2017-04-13 2018-04-09 Комбинированная терапия рака предстательной железы EA201992430A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762485164P 2017-04-13 2017-04-13
PCT/US2018/026661 WO2018191141A1 (en) 2017-04-13 2018-04-09 Combination therapy for prostate cancer

Publications (1)

Publication Number Publication Date
EA201992430A1 true EA201992430A1 (ru) 2020-02-28

Family

ID=62067858

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201992430A EA201992430A1 (ru) 2017-04-13 2018-04-09 Комбинированная терапия рака предстательной железы

Country Status (30)

Country Link
US (3) US20180296574A1 (ru)
EP (3) EP4176878A1 (ru)
JP (3) JP7141408B2 (ru)
KR (1) KR20190134718A (ru)
CN (1) CN110753545A (ru)
AU (2) AU2018251594A1 (ru)
BR (1) BR112019021466A2 (ru)
CA (1) CA3059562A1 (ru)
CL (1) CL2019002871A1 (ru)
CO (1) CO2019011591A2 (ru)
CR (1) CR20190467A (ru)
DK (1) DK3609497T3 (ru)
DO (1) DOP2019000264A (ru)
EA (1) EA201992430A1 (ru)
ES (1) ES2931052T3 (ru)
HR (1) HRP20221327T1 (ru)
HU (1) HUE060460T2 (ru)
JO (1) JOP20190244A1 (ru)
LT (1) LT3609497T (ru)
MA (1) MA48728B1 (ru)
MD (1) MD3609497T2 (ru)
MX (2) MX2019012296A (ru)
NI (1) NI201900105A (ru)
PE (1) PE20200444A1 (ru)
PH (1) PH12019502317A1 (ru)
PL (1) PL3609497T3 (ru)
PT (1) PT3609497T (ru)
RS (1) RS63832B1 (ru)
SG (1) SG11201909552VA (ru)
WO (1) WO2018191141A1 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109640991A (zh) 2016-07-29 2019-04-16 詹森药业有限公司 治疗前列腺癌的方法
WO2020139339A1 (en) * 2018-12-27 2020-07-02 Constellation Pharmaceuticals, Inc. Ezh2 and androgen receptor signaling inhibitors as tools for targeting prostate cancer
CN113546037A (zh) * 2020-04-20 2021-10-26 鲁南制药集团股份有限公司 一种醋酸阿比特龙栓剂及其制备方法
MX2022014003A (es) * 2020-05-08 2022-11-30 Janssen Pharmaceutica Nv Tratamientos del cancer de prostata con combinaciones de acetato de abiraterona y niraparib.
CN114306236B (zh) * 2021-12-15 2022-10-21 湖南慧泽生物医药科技有限公司 用于负载醋酸阿比特龙的自微乳体系及组合物和应用
JP7320903B2 (ja) 2021-12-15 2023-08-04 湖南慧▲澤▼生物医▲薬▼科技有限公司 アビラテロン酢酸エステルを含む組成物及び使用
WO2023194525A1 (en) * 2022-04-07 2023-10-12 Astrazeneca Ab Combination therapy for treating cancer
WO2024203348A1 (ja) * 2023-03-31 2024-10-03 ソニーグループ株式会社 腫瘍の解析方法、腫瘍の解析システム、及び腫瘍の解析データ生成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101528308A (zh) * 2006-08-25 2009-09-09 库伽尔生物科技公司 治疗癌症的方法和组合物
US20080051380A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
PL2336120T3 (pl) 2007-01-10 2014-12-31 Msd Italia Srl Kombinacje zawierające indazole podstawione grupą amidową jako inhibitory polimerazy poli(ADP-rybozy) (PARP)
RU2495035C2 (ru) 2008-01-08 2013-10-10 Мерк Шарп Энд Домэ Лтд Фармацевтически приемлемые соли 2-{4-[(3s)-пиперидин-3-ил]фенил}-2н-индазол-7-карбоксамида
WO2012009475A1 (en) * 2010-07-14 2012-01-19 Oregon Health & Science University Methods of treating cancer with inhibition of lysine-specific demethylase 1
WO2014089324A1 (en) * 2012-12-07 2014-06-12 Calitor Sciences, Llc Substituted cyclic compounds and methods of use

Also Published As

Publication number Publication date
JOP20190244A1 (ar) 2019-10-13
EP3609497B1 (en) 2022-10-12
LT3609497T (lt) 2022-12-12
DOP2019000264A (es) 2020-07-15
RS63832B1 (sr) 2023-01-31
AU2024202346A1 (en) 2024-05-02
PH12019502317A1 (en) 2020-07-06
NI201900105A (es) 2020-03-11
CN110753545A (zh) 2020-02-04
EP4176878A1 (en) 2023-05-10
EP4176879A1 (en) 2023-05-10
KR20190134718A (ko) 2019-12-04
CO2019011591A2 (es) 2020-02-28
MA48728A (fr) 2020-04-08
US20180296574A1 (en) 2018-10-18
BR112019021466A2 (pt) 2020-05-12
JP2024023344A (ja) 2024-02-21
MA48728B1 (fr) 2022-10-31
MD3609497T2 (ro) 2023-03-31
EP3609497A1 (en) 2020-02-19
MX2019012296A (es) 2019-11-28
WO2018191141A1 (en) 2018-10-18
CA3059562A1 (en) 2018-10-18
HUE060460T2 (hu) 2023-03-28
HRP20221327T1 (hr) 2023-03-17
CR20190467A (es) 2020-03-09
PE20200444A1 (es) 2020-02-28
DK3609497T3 (da) 2022-10-31
PL3609497T3 (pl) 2023-01-23
JP2020516646A (ja) 2020-06-11
JP7407880B2 (ja) 2024-01-04
JP7141408B2 (ja) 2022-09-22
ES2931052T3 (es) 2022-12-23
PT3609497T (pt) 2023-01-23
SG11201909552VA (en) 2019-11-28
AU2018251594A1 (en) 2019-10-24
MX2023009569A (es) 2023-08-22
CL2019002871A1 (es) 2019-12-27
JP2022141881A (ja) 2022-09-29
US20220175801A1 (en) 2022-06-09
US20240245710A1 (en) 2024-07-25

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