MA44610A - Formulations liquides de (s)-n-(5-((r)-2-(2,5-difluorophényl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide - Google Patents

Formulations liquides de (s)-n-(5-((r)-2-(2,5-difluorophényl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

Info

Publication number
MA44610A
MA44610A MA044610A MA44610A MA44610A MA 44610 A MA44610 A MA 44610A MA 044610 A MA044610 A MA 044610A MA 44610 A MA44610 A MA 44610A MA 44610 A MA44610 A MA 44610A
Authority
MA
Morocco
Prior art keywords
hydroxypyrrolidine
pyrazolo
difluorophenyl
pyrrolidin
pyrimidin
Prior art date
Application number
MA044610A
Other languages
English (en)
French (fr)
Inventor
Mark Reynolds
Steven A Smith
Original Assignee
Loxo Oncology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58549282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA44610(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Loxo Oncology Inc filed Critical Loxo Oncology Inc
Publication of MA44610A publication Critical patent/MA44610A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
MA044610A 2016-04-04 2017-04-04 Formulations liquides de (s)-n-(5-((r)-2-(2,5-difluorophényl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide MA44610A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662318041P 2016-04-04 2016-04-04
US201662323452P 2016-04-15 2016-04-15
US201662329561P 2016-04-29 2016-04-29

Publications (1)

Publication Number Publication Date
MA44610A true MA44610A (fr) 2019-02-13

Family

ID=58549282

Family Applications (1)

Application Number Title Priority Date Filing Date
MA044610A MA44610A (fr) 2016-04-04 2017-04-04 Formulations liquides de (s)-n-(5-((r)-2-(2,5-difluorophényl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

Country Status (36)

Country Link
US (3) US10137127B2 (cg-RX-API-DMAC7.html)
EP (1) EP3439662B1 (cg-RX-API-DMAC7.html)
JP (1) JP7061602B2 (cg-RX-API-DMAC7.html)
KR (1) KR102400423B1 (cg-RX-API-DMAC7.html)
CN (1) CN109414442B (cg-RX-API-DMAC7.html)
AU (1) AU2017246554B2 (cg-RX-API-DMAC7.html)
CA (1) CA3019671C (cg-RX-API-DMAC7.html)
CL (2) CL2018002806A1 (cg-RX-API-DMAC7.html)
CO (1) CO2018010761A2 (cg-RX-API-DMAC7.html)
CR (1) CR20180501A (cg-RX-API-DMAC7.html)
CU (1) CU20180125A7 (cg-RX-API-DMAC7.html)
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DO (1) DOP2018000214A (cg-RX-API-DMAC7.html)
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FI (1) FI3439662T3 (cg-RX-API-DMAC7.html)
GE (1) GEP20227339B (cg-RX-API-DMAC7.html)
HR (1) HRP20241282T1 (cg-RX-API-DMAC7.html)
HU (1) HUE068971T2 (cg-RX-API-DMAC7.html)
IL (2) IL304018A (cg-RX-API-DMAC7.html)
LT (1) LT3439662T (cg-RX-API-DMAC7.html)
MA (1) MA44610A (cg-RX-API-DMAC7.html)
MX (1) MX386416B (cg-RX-API-DMAC7.html)
NI (1) NI201800102A (cg-RX-API-DMAC7.html)
PE (1) PE20181888A1 (cg-RX-API-DMAC7.html)
PH (1) PH12018502124B1 (cg-RX-API-DMAC7.html)
PL (1) PL3439662T3 (cg-RX-API-DMAC7.html)
PT (1) PT3439662T (cg-RX-API-DMAC7.html)
RS (1) RS65987B1 (cg-RX-API-DMAC7.html)
SA (1) SA518400168B1 (cg-RX-API-DMAC7.html)
SG (1) SG11201808559PA (cg-RX-API-DMAC7.html)
SI (1) SI3439662T1 (cg-RX-API-DMAC7.html)
TN (1) TN2018000335A1 (cg-RX-API-DMAC7.html)
TW (1) TWI746537B (cg-RX-API-DMAC7.html)
UA (1) UA125026C2 (cg-RX-API-DMAC7.html)
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