UA91677C2 - Макроциклические соединения как ингибиторы вирусной репликации - Google Patents
Макроциклические соединения как ингибиторы вирусной репликацииInfo
- Publication number
- UA91677C2 UA91677C2 UAA200611368A UAA200611368A UA91677C2 UA 91677 C2 UA91677 C2 UA 91677C2 UA A200611368 A UAA200611368 A UA A200611368A UA A200611368 A UAA200611368 A UA A200611368A UA 91677 C2 UA91677 C2 UA 91677C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methods
- inhibitors
- hcv replication
- macrocyclic compounds
- subject compound
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Группа изобретений представляет совокупность общих формул И-ХИХ и их соединений, в том числе фармацевтические композиции, которые содержат эту совокупность.Группа изобретений также предусматривает способы лечения, включая способы лечения флавивирусной инфекции, в частности вируса гепатита С, и способы лечения цирроза печени.Способы вообще включают назначение пациенту, который нуждается в лечении, эффективного количества соединения или композиции.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55816104P | 2004-03-30 | 2004-03-30 | |
PCT/US2005/010494 WO2005095403A2 (en) | 2004-03-30 | 2005-03-29 | Macrocyclic compounds as inhibitors of viral replication |
Publications (1)
Publication Number | Publication Date |
---|---|
UA91677C2 true UA91677C2 (ru) | 2010-08-25 |
Family
ID=37955155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200611368A UA91677C2 (ru) | 2004-03-30 | 2005-03-29 | Макроциклические соединения как ингибиторы вирусной репликации |
Country Status (5)
Country | Link |
---|---|
CN (1) | CN1938311A (ru) |
CU (1) | CU20090112A6 (ru) |
TN (1) | TNSN06308A1 (ru) |
UA (1) | UA91677C2 (ru) |
ZA (1) | ZA200608798B (ru) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100167302A1 (en) * | 2007-09-10 | 2010-07-01 | Novartis Ag | Method for predicting the response of a subject suffering from a viral infection of the liver to an antiviral therapy |
CA2952692C (en) | 2008-09-22 | 2020-04-28 | Array Biopharma Inc. | Substituted imidazo[1,2b]pyridazine compounds |
AU2009308465B2 (en) | 2008-10-22 | 2015-02-12 | Array Biopharma Inc. | Substituted pyrazolo[1,5-a]pyrimidine compounds as TRK kinase inhibitors |
BRPI1008918A2 (pt) | 2009-02-27 | 2016-03-15 | Ortho Mcneil Janssen Pharm | sal amorfo de um inibidor macrocíclico de hcv |
AR077468A1 (es) | 2009-07-09 | 2011-08-31 | Array Biopharma Inc | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
KR20120110090A (ko) * | 2009-09-28 | 2012-10-09 | 에프. 호프만-라 로슈 리미티드 | C형 간염 바이러스 복제의 신규한 마크로시클릭 저해제 |
NZ601629A (en) * | 2010-01-27 | 2014-11-28 | Pharma Ltd Ab | Polyheterocyclic compounds highly potent as hcv inhibitors |
SI2918588T1 (sl) | 2010-05-20 | 2017-09-29 | Array Biopharma,Inc. | Makrociklične spojine kot inhibitorji TRK kinaze |
GB201116559D0 (en) * | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
JP6914834B2 (ja) | 2014-11-16 | 2021-08-04 | アレイ バイオファーマ インコーポレイテッド | (S)−N−(5−((R)−2−(2,5−ジフルオロフェニル)−ピロリジン−1−イル)−ピラゾロ[1,5−a]ピリミジン−3−イル)−3−ヒドロキシピロリジン−1−カルボキサミド硫酸水素塩の結晶形 |
WO2017075107A1 (en) | 2015-10-26 | 2017-05-04 | Nanda Nisha | Point mutations in trk inhibitor-resistant cancer and methods relating to the same |
CN107043405B (zh) * | 2016-02-05 | 2021-11-19 | 爱博新药研发(上海)有限公司 | 多环杂环化合物的晶型、其制备方法、应用及组合物 |
CU20180125A7 (es) | 2016-04-04 | 2019-05-03 | Loxo Oncology Inc | Formulaciones líquidas de (s)-n-(5-((r)-2-(2,5-difluorofenil) -pirrolidin-1-il)-pirazolo[1,5-alpirimidin-3-il)-3 hidroxipirrolidina-1-carboxamida |
US10045991B2 (en) | 2016-04-04 | 2018-08-14 | Loxo Oncology, Inc. | Methods of treating pediatric cancers |
HRP20230704T1 (hr) | 2016-05-18 | 2023-10-27 | Loxo Oncology, Inc. | Priprava (s)-n-(5-((r)-2-(2,5-difluorfenil)pirolidin-1-il)pirazolo[1,5-a]pirimidin-3-il)-3-hidroksipirolidin-1-karboksamida |
JOP20190092A1 (ar) | 2016-10-26 | 2019-04-25 | Array Biopharma Inc | عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها |
JOP20190213A1 (ar) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | مركبات حلقية ضخمة كمثبطات لكيناز ros1 |
-
2005
- 2005-03-29 CN CN 200580010503 patent/CN1938311A/zh active Pending
- 2005-03-29 UA UAA200611368A patent/UA91677C2/ru unknown
-
2006
- 2006-09-27 TN TNP2006000308A patent/TNSN06308A1/en unknown
- 2006-10-23 ZA ZA200608798A patent/ZA200608798B/xx unknown
-
2009
- 2009-06-24 CU CU20090112A patent/CU20090112A6/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN1938311A (zh) | 2007-03-28 |
TNSN06308A1 (en) | 2007-12-03 |
CU20090112A6 (es) | 2012-03-15 |
ZA200608798B (en) | 2008-06-25 |
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