|
AU6044699A
(en)
*
|
1998-09-17 |
2000-04-03 |
Akesis Pharmaceuticals, Inc. |
Compositions and methods for treatment of glucose metabolism disorders
|
|
US6376549B1
(en)
*
|
1998-09-17 |
2002-04-23 |
Akesis Pharmaceuticals, Inc. |
Metforimin-containing compositions for the treatment of diabetes
|
|
DE19940130A1
(de)
*
|
1999-08-24 |
2001-03-01 |
Probiodrug Ges Fuer Arzneim |
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
|
|
US20040152745A1
(en)
*
|
1999-11-12 |
2004-08-05 |
Guilford Pharmaceuticals, Inc. |
Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors
|
|
EP1228061A4
(en)
*
|
1999-11-12 |
2004-12-15 |
Guilford Pharm Inc |
DIPEPTIDYL PEPTIDASE IV INHIBITORS; METHODS OF MANUFACTURE AND USE OF SAID INHIBITORS
|
|
GB9928330D0
(en)
*
|
1999-11-30 |
2000-01-26 |
Ferring Bv |
Novel antidiabetic agents
|
|
IL150204A0
(en)
*
|
1999-12-23 |
2002-12-01 |
Novartis Ag |
Use of hypoglycemic agent for treating impaired glucose metabolism
|
|
US6380398B2
(en)
|
2000-01-04 |
2002-04-30 |
Novo Nordisk A/S |
Therapeutically active and selective heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
|
US20080076811A1
(en)
*
|
2000-01-21 |
2008-03-27 |
Bork Balkan |
Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
|
|
ES2487897T3
(es)
*
|
2000-01-21 |
2014-08-25 |
Novartis Ag |
Combinaciones que consisten de inhibidores de la dipeptidilpeptidasa-IV y agentes antidiabéticos
|
|
JP2003520849A
(ja)
*
|
2000-01-24 |
2003-07-08 |
ノボ ノルディスク アクティーゼルスカブ |
酵素ｄｐｐ−ｉｖの阻害剤であるｎ−置換２−シアノピロールおよび−ピロリン
|
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
US6432969B1
(en)
|
2000-06-13 |
2002-08-13 |
Novartis Ag |
N-(substituted glycyl)-2 cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
|
WO2002002560A2
(en)
|
2000-07-04 |
2002-01-10 |
Novo Nordisk A/S |
Purine-2,6-diones which are inhibitors of the enzyme dipeptidyl peptidase iv (dpp-iv)
|
|
PE20020617A1
(es)
*
|
2000-08-22 |
2002-08-05 |
Novartis Ag |
Composicion que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina o un sensibilizante a la insulina
|
|
US20060089389A1
(en)
*
|
2000-08-22 |
2006-04-27 |
Malcolm Allison |
Combination
|
|
US7371721B2
(en)
*
|
2000-09-18 |
2008-05-13 |
Sanos Bioscience A/S |
Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
|
|
US20080249016A1
(en)
*
|
2000-09-18 |
2008-10-09 |
Sanos Bioscience A/S |
Use of GLP-2 in a combination treatment for bone-related disorders
|
|
US20070135345A1
(en)
*
|
2000-09-18 |
2007-06-14 |
Henriksen Dennis B |
Use of GLP-2 for the treatment or prevention, of bone-related disorders
|
|
US6770620B2
(en)
|
2000-09-18 |
2004-08-03 |
Sanos Bioscience A/S |
Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
|
|
PT1325910E
(pt)
*
|
2000-10-06 |
2008-10-27 |
Mitsubishi Tanabe Pharma Corp |
Compostos de anel alifático de cinco membros contendo azoto
|
|
UA74023C2
(en)
*
|
2000-11-10 |
2005-10-17 |
Taisho Pharmaceutical Co Ltd |
Cyanopyrrolidine derivatives
|
|
TWI243162B
(en)
*
|
2000-11-10 |
2005-11-11 |
Taisho Pharmaceutical Co Ltd |
Cyanopyrrolidine derivatives
|
|
US20040180925A1
(en)
*
|
2000-12-27 |
2004-09-16 |
Kenji Matsuno |
Dipeptidylpeptidase-IV inhibitor
|
|
GB0109146D0
(en)
*
|
2001-04-11 |
2001-05-30 |
Ferring Bv |
Treatment of type 2 diabetes
|
|
US20030060494A1
(en)
*
|
2001-05-18 |
2003-03-27 |
Nobuyuki Yasuda |
Pharmaceutical use of N-carbamoylazole derivatives
|
|
ATE381539T1
(de)
|
2001-06-20 |
2008-01-15 |
Merck & Co Inc |
Dipeptidylpeptidase-hemmer zur behandlung von diabetes
|
|
DE60209348T2
(de)
|
2001-06-20 |
2006-10-12 |
Merck & Co., Inc. |
Dipeptidylpeptidase-hemmer zur behandlung von diabetes
|
|
CN1990469A
(zh)
|
2001-06-27 |
2007-07-04 |
史密丝克莱恩比彻姆公司 |
作为二肽酶抑制剂的氟代吡咯烷
|
|
ATE380175T1
(de)
*
|
2001-06-27 |
2007-12-15 |
Smithkline Beecham Corp |
Pyrrolidine als dipeptidyl peptidase inhibitoren
|
|
EP1399433B1
(en)
*
|
2001-06-27 |
2007-08-22 |
Smithkline Beecham Corporation |
Fluoropyrrolidines as dipeptidyl peptidase inhibitors
|
|
US6709651B2
(en)
*
|
2001-07-03 |
2004-03-23 |
B.M.R.A. Corporation B.V. |
Treatment of substance P-related disorders
|
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
|
US6861440B2
(en)
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
|
CA2464995A1
(en)
*
|
2001-10-31 |
2003-05-08 |
Novartis Ag |
Methods to treat diabetes and related conditions based on polymorphisms in the tcf1 gene
|
|
US20050101638A1
(en)
*
|
2002-11-08 |
2005-05-12 |
Webb Randy L. |
Combination of organic compounds
|
|
US20030135663A1
(en)
*
|
2002-01-16 |
2003-07-17 |
Sun Microsystems, Inc. |
Method, system, and program for including device parameters from a device driver in a configuration file
|
|
ATE472536T1
(de)
|
2002-02-13 |
2010-07-15 |
Hoffmann La Roche |
Pyridin- und pyrimidin-derivate
|
|
DE60302336T2
(de)
|
2002-02-13 |
2006-08-03 |
F. Hoffmann-La Roche Ag |
Neue pyridin- und quinolin-derivate
|
|
US7074798B2
(en)
|
2002-02-25 |
2006-07-11 |
Eisai Co., Ltd |
Xanthine derivative and DPPIV inhibitor
|
|
JP2005526811A
(ja)
*
|
2002-03-25 |
2005-09-08 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病の治療または予防用β−アミノ複素環式ジペプチジルペプチダーゼ阻害剤
|
|
CA2487297C
(en)
*
|
2002-06-03 |
2011-08-09 |
Novartis Ag |
The use of substituted cyanopyrrolidines and combination preparations containing them for treating hyperlipidemia and associated diseases
|
|
US6710040B1
(en)
*
|
2002-06-04 |
2004-03-23 |
Pfizer Inc. |
Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors
|
|
JP2004026678A
(ja)
*
|
2002-06-24 |
2004-01-29 |
Microbial Chem Res Found |
２型糖尿病治療剤
|
|
AU2003248259A1
(en)
*
|
2002-07-10 |
2004-02-02 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel azetidine derivative or salt thereof
|
|
DE60330485D1
(de)
|
2002-07-15 |
2010-01-21 |
Merck & Co Inc |
Zur behandlung von diabetes
|
|
TW200401635A
(en)
*
|
2002-07-23 |
2004-02-01 |
Yamanouchi Pharma Co Ltd |
2-Cyano-4-fluoropyrrolidine derivative or salt thereof
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
ATE368647T1
(de)
*
|
2002-09-19 |
2007-08-15 |
Abbott Lab |
Pharmazeutische zusammensetzung und ihre verwendung als inhibitoren von der dipeptidyl peptidase iv (dpp-iv)
|
|
ES2291680T3
(es)
|
2002-10-07 |
2008-03-01 |
MERCK & CO., INC. |
Antidiabeticos beta-amino heterociclicos inhibidores de la dipeptidil peptidasa.
|
|
JP4352001B2
(ja)
|
2002-10-18 |
2009-10-28 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病の治療または予防のためのベータ−アミノ複素環式ジペプチジルペプチダーゼ阻害剤
|
|
CA2504735C
(en)
|
2002-11-07 |
2009-06-23 |
Merck & Co., Inc. |
Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
EP1578414A4
(en)
*
|
2002-12-04 |
2007-10-24 |
Merck & Co Inc |
PHENYLALANINE DERIVATIVES ALSDIPEPTIDYL-PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
|
|
US20060052382A1
(en)
*
|
2002-12-20 |
2006-03-09 |
Duffy Joseph L |
3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
NZ540612A
(en)
|
2003-01-14 |
2008-02-29 |
Arena Pharm Inc |
1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
|
AU2004206812A1
(en)
*
|
2003-01-17 |
2004-08-05 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
CA2513684A1
(en)
|
2003-01-31 |
2004-08-19 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
US20040242568A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
PE20050021A1
(es)
*
|
2003-04-16 |
2005-03-15 |
Novartis Ag |
Procedimiento para la preparacion de 2-cianopirrolidina n-sustituida
|
|
GB0308854D0
(en)
*
|
2003-04-16 |
2003-05-21 |
Novartis Ag |
Organic compounds
|
|
CA2524531A1
(en)
|
2003-05-14 |
2004-12-02 |
Merck And Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
US7638638B2
(en)
|
2003-05-14 |
2009-12-29 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
|
AU2004247068A1
(en)
|
2003-06-06 |
2004-12-23 |
Merck & Co., Inc. |
Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
CA2527806A1
(en)
*
|
2003-06-17 |
2004-12-29 |
Merck & Co., Inc. |
Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
CA2529443C
(en)
|
2003-06-20 |
2012-06-05 |
F. Hoffmann-La Roche Ag |
Pyrido[2,1-a]-isoquinoline derivatives as dpp-iv inhibitors
|
|
JP4445504B2
(ja)
|
2003-06-20 |
2010-04-07 |
エフ．ホフマン−ラ ロシュ アーゲー |
Ｄｐｐ−ｉｖ阻害剤としてのヘキサヒドロピリドイソキノリン
|
|
AR045047A1
(es)
|
2003-07-11 |
2005-10-12 |
Arena Pharm Inc |
Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
|
|
WO2005011581A2
(en)
|
2003-07-31 |
2005-02-10 |
Merck & Co., Inc. |
Hexahydrodiazepinones as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7790736B2
(en)
|
2003-08-13 |
2010-09-07 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
US7169926B1
(en)
|
2003-08-13 |
2007-01-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
US7678909B1
(en)
|
2003-08-13 |
2010-03-16 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
EP1699777B1
(en)
|
2003-09-08 |
2012-12-12 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
WO2005025554A2
(en)
*
|
2003-09-09 |
2005-03-24 |
Japan Tobacco Inc. |
Dipeptidyl peptidase iv inhibitor
|
|
WO2005033099A2
(en)
*
|
2003-10-03 |
2005-04-14 |
Glenmark Pharmaceuticals Ltd. |
Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof
|
|
NZ546887A
(en)
*
|
2003-11-03 |
2009-04-30 |
Probiodrug Ag |
Combinations useful for the treatment of neuronal disorders
|
|
CA2541212A1
(en)
*
|
2003-11-04 |
2005-05-19 |
Wallace T. Ashton |
Fused phenylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
PL1689757T3
(pl)
|
2003-11-12 |
2015-05-29 |
Sino Med Int Alliance Inc |
Heterocykliczne związki kwasu boronowego
|
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7576121B2
(en)
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
RU2385723C2
(ru)
*
|
2003-11-17 |
2010-04-10 |
Новартис Аг |
Применение ингибиторов дипептидилпептидазы iv
|
|
WO2005049022A2
(en)
|
2003-11-17 |
2005-06-02 |
Novartis Ag |
Use of dipeptidyl peptidase iv inhibitors
|
|
PT1715893E
(pt)
|
2004-01-20 |
2009-10-20 |
Novartis Pharma Ag |
Formulação para compressão directa e processos
|
|
AU2005210285B2
(en)
*
|
2004-02-05 |
2008-01-24 |
Kyorin Pharmaceutical Co., Ltd. |
Bicycloester derivative
|
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
|
JPWO2005077900A1
(ja)
*
|
2004-02-18 |
2007-10-18 |
杏林製薬株式会社 |
ビシクロアミド誘導体
|
|
BRPI0507905A
(pt)
*
|
2004-02-20 |
2007-07-10 |
Novartis Ag |
uso de compostos orgánicos
|
|
WO2005082847A1
(ja)
*
|
2004-02-27 |
2005-09-09 |
Kyorin Pharmaceutical Co., Ltd. |
ビシクロ誘導体
|
|
AU2005221678B2
(en)
*
|
2004-03-09 |
2008-10-09 |
National Health Research Institutes |
Pyrrolidine compounds
|
|
US7732446B1
(en)
|
2004-03-11 |
2010-06-08 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
CN102079743B
(zh)
|
2004-03-15 |
2020-08-25 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
|
US7741082B2
(en)
*
|
2004-04-14 |
2010-06-22 |
Bristol-Myers Squibb Company |
Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
|
|
TW200604167A
(en)
*
|
2004-04-27 |
2006-02-01 |
Astellas Pharma Inc |
Pyrrolidine derivatives
|
|
EP1756074A4
(en)
*
|
2004-05-04 |
2010-05-19 |
Merck Sharp & Dohme |
1,2,4-OXADIAZOLE DERIVATIVES AS DIPEPTIDYLPEPTIDASE IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
|
|
CA2564884A1
(en)
*
|
2004-05-18 |
2005-12-08 |
Merck & Co., Inc. |
Cyclohexylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
EP1753730A1
(en)
|
2004-06-04 |
2007-02-21 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
WO2005117861A1
(en)
*
|
2004-06-04 |
2005-12-15 |
Novartis Ag |
Use of organic compounds
|
|
JP2008505975A
(ja)
|
2004-07-12 |
2008-02-28 |
フェノミックス コーポレーション |
制約されたシアノ化合物
|
|
WO2006019965A2
(en)
|
2004-07-16 |
2006-02-23 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
|
ATE553077T1
(de)
|
2004-07-23 |
2012-04-15 |
Nuada Llc |
Peptidaseinhibitoren
|
|
TW200608967A
(en)
|
2004-07-29 |
2006-03-16 |
Sankyo Co |
Pharmaceutical compositions containing with diabetic agent
|
|
PE20060652A1
(es)
*
|
2004-08-27 |
2006-08-11 |
Novartis Ag |
Composiciones farmaceuticas de liberacion inmediata que comprenden granulos de fusion
|
|
NZ554515A
(en)
|
2004-10-12 |
2009-12-24 |
Glenmark Pharmaceuticals Sa |
Novel dipeptidyl peptidase IV inhibitors, pharmaceutical compositions containing them, and process for their preparation
|
|
MX2007004934A
(es)
*
|
2004-10-25 |
2007-06-12 |
Novartis Ag |
Combinacion de inhibidor de dpp-iv, anti-diabetico de ppar, y metformina.
|
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
KR100904829B1
(ko)
|
2004-12-20 |
2009-06-25 |
에프. 호프만-라 로슈 아게 |
4-아미노피페리딘 유도체
|
|
US7411093B2
(en)
*
|
2004-12-20 |
2008-08-12 |
Hoffman-La Roche Inc. |
Aminocycloalkanes as DPP-IV inhibitors
|
|
EP2805953B1
(en)
|
2004-12-21 |
2016-03-09 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
|
GT200600008A
(es)
*
|
2005-01-18 |
2006-08-09 |
|
Formulacion de compresion directa y proceso
|
|
JP2008024592A
(ja)
*
|
2005-01-28 |
2008-02-07 |
Taisho Pharmaceut Co Ltd |
シアノピロリジン誘導体含有固形製剤用組成物、それを含有する固形製剤及びその製造方法
|
|
WO2006090244A1
(en)
*
|
2005-02-22 |
2006-08-31 |
Glenmark Pharmaceuticals S.A. |
New adamantane derivatives as dipeptidyl, peptidase iv inhibitors, processes for their preparation, and pharmaceutical compositions containing them
|
|
TWI357902B
(en)
|
2005-04-01 |
2012-02-11 |
Lg Life Science Ltd |
Dipeptidyl peptidase-iv inhibiting compounds, meth
|
|
AU2006239929B2
(en)
|
2005-04-22 |
2011-11-03 |
Alantos Pharmaceuticals Holding, Inc. |
Dipeptidyl peptidase-IV inhibitors
|
|
US7825139B2
(en)
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
EP2356997A1
(en)
|
2005-06-06 |
2011-08-17 |
Georgetown University |
Compositions and methods for lipo modeling
|
|
MY152185A
(en)
|
2005-06-10 |
2014-08-29 |
Novartis Ag |
Modified release 1-[(3-hydroxy-adamant-1-ylamino)-acetyl]-pyrrolidine-2(s)-carbonitrile formulation
|
|
WO2006134613A2
(en)
*
|
2005-06-17 |
2006-12-21 |
Aurigene Discovery Technologies Limited |
Novel 5-substituted indole derivatives as dipeptidyl peptidase iv (dpp-iv) inhibitors
|
|
MX2008000468A
(es)
*
|
2005-07-12 |
2008-03-11 |
Novartis Ag |
Combinacion de un inhibidor de dipeptidil-peptidasa-iv y un antagonista del receptor canabinoide cb1.
|
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
CN101238099A
(zh)
*
|
2005-08-04 |
2008-08-06 |
诺瓦提斯公司 |
维格列汀的盐
|
|
GT200600381A
(es)
|
2005-08-25 |
2007-03-28 |
|
Compuestos organicos
|
|
MY147393A
(en)
|
2005-09-14 |
2012-11-30 |
Takeda Pharmaceutical |
Administration of dipeptidyl peptidase inhibitors
|
|
KR101368988B1
(ko)
|
2005-09-16 |
2014-02-28 |
다케다 야쿠힌 고교 가부시키가이샤 |
디펩티딜 펩티다제 억제제
|
|
TW200738266A
(en)
*
|
2005-09-29 |
2007-10-16 |
Sankyo Co |
Pharmaceutical agent containing insulin resistance improving agent
|
|
JOP20180109A1
(ar)
*
|
2005-09-29 |
2019-01-30 |
Novartis Ag |
تركيبة جديدة
|
|
BRPI0616949A2
(pt)
*
|
2005-10-07 |
2011-07-05 |
Waratah Pharmaceuticals Inc |
composição farmacêutica, uso de uma composição, e, kit
|
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
|
US20090054512A1
(en)
*
|
2006-01-06 |
2009-02-26 |
Foley James E |
Use of organic compounds
|
|
AU2007224066B2
(en)
|
2006-03-08 |
2011-10-27 |
Kyorin Pharmaceutical Co., Ltd. |
Method for producing aminoacetylpyrrolidinecarbonitrile derivative and production intermediate thereof
|
|
CA2646598C
(en)
|
2006-03-21 |
2014-08-19 |
Amylin Pharmaceuticals, Inc. |
Peptide-peptidase inhibitor conjugates and methods of using same
|
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
BRPI0709894A2
(pt)
*
|
2006-04-03 |
2011-07-26 |
Matrix Lab Ltd |
inibidores de dipeptidil peptidase iv e processos para sua preparaÇço e composiÇço farmacÊuticas contendo-os
|
|
JP2009532454A
(ja)
*
|
2006-04-03 |
2009-09-10 |
マトリックス ラボラトリーズ リミテッド |
新規ジペプチジルペプチダーゼｉｖ阻害因子およびその調製方法、ならび該阻害因子を含む医薬組成物
|
|
CA2618488C
(en)
|
2006-04-11 |
2010-07-13 |
Arena Pharmaceuticals, Inc. |
Methods of using gpr119 receptor to identify compounds useful for increasing bone mass in an individual
|
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
MX2008014024A
(es)
|
2006-05-04 |
2008-11-14 |
Boehringer Ingelheim Int |
Formas poliformas.
|
|
US20100029554A1
(en)
|
2006-05-26 |
2010-02-04 |
Amylin Pharmaceuticals, Inc. |
Composition and Methods for Treatment of Congestive Heart Failure
|
|
EP2063890A1
(en)
|
2006-09-07 |
2009-06-03 |
Nycomed GmbH |
Combination treatment for diabetes mellitus
|
|
CN103211819A
(zh)
*
|
2006-09-13 |
2013-07-24 |
武田药品工业株式会社 |
2-[6-(3-氨基-哌啶-1-基)-3-甲基-2,4-二氧代-3,4-二氢-2h-嘧啶-1-基甲基]-4-氟-苄腈的用途
|
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
|
EP2118056A2
(en)
*
|
2007-01-10 |
2009-11-18 |
Medichem, S.A. |
Process for preparing vildagliptin
|
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
|
US20080064701A1
(en)
*
|
2007-04-24 |
2008-03-13 |
Ramesh Sesha |
Anti-diabetic combinations
|
|
JPWO2008114857A1
(ja)
*
|
2007-03-22 |
2010-07-08 |
杏林製薬株式会社 |
アミノアセチルピロリジンカルボニトリル誘導体の製造方法
|
|
JP5616630B2
(ja)
|
2007-04-03 |
2014-10-29 |
田辺三菱製薬株式会社 |
ジペプチジルペプチダーゼ４阻害化合物と甘味料との併用
|
|
DE102007022007A1
(de)
*
|
2007-05-08 |
2008-11-13 |
Schebo Biotech Ag |
Neuartike Pharmazeutika, Verfahren zu ihrer Herstellung und ihre Verwendung in der Prophylaxe und Therapie von ZNS-Erkrankungen und Diabetes
|
|
WO2008149345A2
(en)
|
2007-06-04 |
2008-12-11 |
Ben-Gurion University Of The Negev Research And Development Authority |
Tri-aryl compounds and compositions comprising the same
|
|
PE20090938A1
(es)
|
2007-08-16 |
2009-08-08 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
|
|
ES2733348T3
(es)
*
|
2007-08-17 |
2019-11-28 |
Boehringer Ingelheim Int |
Derivados de purina para uso en el tratamiento de enfermedades relacionadas con FAP
|
|
WO2009037719A1
(en)
*
|
2007-09-21 |
2009-03-26 |
Lupin Limited |
Novel compounds as dipeptidyl peptidase iv (dpp iv) inhibitors
|
|
US20090082420A1
(en)
*
|
2007-09-25 |
2009-03-26 |
Protia, Llc |
Deuterium-enriched vildagliptin
|
|
US8598314B2
(en)
*
|
2007-09-27 |
2013-12-03 |
Amylin Pharmaceuticals, Llc |
Peptide-peptidase-inhibitor conjugates and methods of making and using same
|
|
EP2247602B1
(en)
|
2007-11-30 |
2013-04-03 |
Novartis AG |
Adamantyl o-glucuronide derivatives as inhibitors of dipeptidyl peptidase iv for the treatment of diabetes
|
|
WO2009074829A1
(en)
*
|
2007-12-12 |
2009-06-18 |
Astrazeneca Ab |
Peptidyl nitriles and use thereof as dipeptidyl peptidase i inhibitors
|
|
CA2710109C
(en)
|
2007-12-21 |
2016-07-19 |
Lg Life Sciences Ltd. |
Dipeptidyl peptidase-iv inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent
|
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
|
US8551524B2
(en)
|
2008-03-14 |
2013-10-08 |
Iycus, Llc |
Anti-diabetic combinations
|
|
PE20140960A1
(es)
|
2008-04-03 |
2014-08-15 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
EP2108960A1
(en)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
|
|
PE20100156A1
(es)
*
|
2008-06-03 |
2010-02-23 |
Boehringer Ingelheim Int |
Tratamiento de nafld
|
|
WO2009155309A1
(en)
*
|
2008-06-19 |
2009-12-23 |
Concert Pharmaceuticals, Inc. |
Substituted cyanopyrrolidine derivatives
|
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
|
BRPI0916997A2
(pt)
|
2008-08-06 |
2020-12-15 |
Boehringer Ingelheim International Gmbh |
Inibidor de dpp-4 e seu uso
|
|
CA2732984A1
(en)
*
|
2008-08-07 |
2010-02-11 |
Kyorin Pharmaceutical Co., Ltd. |
Process for production of bicyclo[2.2.2]octylamine derivative
|
|
KR20110044780A
(ko)
*
|
2008-08-14 |
2011-04-29 |
교린 세이야꾸 가부시키 가이샤 |
안정화된 의약 조성물
|
|
EP2326326B1
(en)
*
|
2008-08-15 |
2019-10-09 |
Boehringer Ingelheim International GmbH |
Dpp-4 inhibitors for use for the treatment of wound healing in diabetic patients
|
|
CZ2008512A3
(cs)
|
2008-08-26 |
2010-03-10 |
Zentiva, A. S |
Zpusob prípravy vysoce cistého vildagliptinu
|
|
WO2010029089A2
(en)
|
2008-09-10 |
2010-03-18 |
Boehringer Ingelheim International Gmbh |
Combination therapy for the treatment of diabetes and related conditions
|
|
CN102850330B
(zh)
*
|
2008-09-23 |
2014-10-15 |
成都地奥制药集团有限公司 |
经溴代的制备n取代的吡咯烷衍生物的方法
|
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
|
EP2382216A1
(en)
|
2008-12-23 |
2011-11-02 |
Boehringer Ingelheim International GmbH |
Salt forms of organic compound
|
|
AR074990A1
(es)
|
2009-01-07 |
2011-03-02 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
|
|
AU2010204144B2
(en)
|
2009-01-09 |
2012-02-16 |
Orchid Research Laboratories Ltd. |
Dipeptidyl peptidase IV inhibitors
|
|
AR075204A1
(es)
|
2009-01-29 |
2011-03-16 |
Boehringer Ingelheim Int |
Inhibidores de dpp-4 y composiciones farmaceuticas que los comprenden, utiles para tratar enfermedades metabolicas en pacientes pediatricos, particularmente diabetes mellitus tipo 2
|
|
AU2010212823B2
(en)
|
2009-02-13 |
2016-01-28 |
Boehringer Ingelheim International Gmbh |
Antidiabetic medications comprising a DPP-4 inhibitor (linagliptin) optionally in combination with other antidiabetics
|
|
KR101694136B1
(ko)
|
2009-02-13 |
2017-01-09 |
베링거 인겔하임 인터내셔날 게엠베하 |
Ｓｇｌｔ２ 억제제, ｄｐｐ－ｉｖ 억제제 및 임의로 추가의 당뇨병 치료제를 포함하는 약제학적 조성물 및 이의 용도
|
|
WO2010110436A1
(ja)
|
2009-03-27 |
2010-09-30 |
杏林製薬株式会社 |
塩基性添加剤を含有するマトリックス型徐放性製剤
|
|
AU2010244218B2
(en)
|
2009-05-07 |
2012-07-19 |
Astrazeneca Ab |
Substituted 1-cyanoethylheterocyclylcarboxamide compounds 750
|
|
EP2430018B1
(en)
|
2009-05-15 |
2013-07-03 |
Novartis AG |
Benzoxazolone derivatives as aldosterone symthase inhibitors
|
|
RS53275B
(en)
|
2009-05-15 |
2014-08-29 |
Novartis Ag |
ARYL-PYRIDINE AS AN ALDOSTERON SYNTHASE INHIBITOR
|
|
MX2011012628A
(es)
|
2009-05-28 |
2011-12-14 |
Novartis Ag |
Derivados amino-propionicos sustituidos como inhibidores de neprilisina.
|
|
EP3048100A1
(en)
|
2009-05-28 |
2016-07-27 |
Novartis AG |
Substituted aminobutyric derivatives as neprilysin inhibitors
|
|
GB2483614B
(en)
|
2009-06-18 |
2014-12-03 |
Lupin Ltd |
2-Amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent dpp-iv inhibitors
|
|
AR077642A1
(es)
|
2009-07-09 |
2011-09-14 |
Arena Pharm Inc |
Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
EA034049B1
(ru)
*
|
2009-07-31 |
2019-12-23 |
КРКА, д.д., НОВО МЕСТО |
Гранулят, включающий вилдаглиптин, способ его получения и фармацевтическая композиция
|
|
AU2010289871B2
(en)
|
2009-09-02 |
2014-07-10 |
Merck Sharp & Dohme Corp. |
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
JP5696856B2
(ja)
|
2009-09-03 |
2015-04-08 |
バイオエナジェニックス |
Ｐａｓｋの阻害用複素環式化合物
|
|
EP2295083A1
(de)
|
2009-09-15 |
2011-03-16 |
Ratiopharm GmbH |
Pharmazeutische Zusammensetzung mit den Wirkstoffen Metformin und Sitagliptin oder Vildagliptin
|
|
EA201200486A1
(ru)
|
2009-09-15 |
2012-08-30 |
Серулин Фарма Инк. |
Лечение онкологических заболеваний
|
|
HUP0900638A2
(en)
|
2009-10-07 |
2011-05-30 |
Egyt Gyogyszervegyeszeti Gyar |
Adducts of inorganic salts basea on vildaelitpin applicable for preparation of pharmaceutical compositions
|
|
MX2012004078A
(es)
|
2009-10-09 |
2012-07-25 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
|
EP2308847B1
(en)
|
2009-10-09 |
2014-04-02 |
EMC microcollections GmbH |
Substituted pyridines as inhibitors of dipeptidyl peptidase IV and their application for the treatment of diabetes and related diseases
|
|
EP2993169B1
(en)
|
2009-11-17 |
2017-12-20 |
Novartis AG |
Aryl-pyridine derivatives as aldosterone synthase inhibitors
|
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
|
CN107261150A
(zh)
|
2009-11-23 |
2017-10-20 |
布鲁林克医药品公司 |
用于传递治疗剂的基于环糊精的聚合物
|
|
EP2504002B1
(en)
|
2009-11-27 |
2019-10-09 |
Boehringer Ingelheim International GmbH |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
|
CN102666535B
(zh)
|
2009-11-30 |
2015-02-25 |
诺华股份有限公司 |
作为醛固酮合酶抑制剂的咪唑衍生物
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
US8796468B2
(en)
|
2009-12-22 |
2014-08-05 |
Shionogi & Co., Ltd. |
Adamantanamine derivative
|
|
WO2011090940A1
(en)
|
2010-01-19 |
2011-07-28 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
|
EP2538783B1
(en)
|
2010-02-22 |
2016-06-01 |
Merck Sharp & Dohme Corp. |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
|
CN101798270B
(zh)
*
|
2010-02-25 |
2013-04-17 |
东华大学 |
一种3-氨基-1-金刚烷醇的制备方法
|
|
WO2011113947A1
(en)
|
2010-03-18 |
2011-09-22 |
Boehringer Ingelheim International Gmbh |
Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
|
|
EP2556056A1
(en)
|
2010-04-06 |
2013-02-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
PT2566469T
(pt)
|
2010-05-05 |
2023-01-10 |
Boehringer Ingelheim Int |
Terapia de combinação
|
|
US8980929B2
(en)
|
2010-05-21 |
2015-03-17 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
|
CN102260265B
(zh)
|
2010-05-24 |
2015-09-02 |
上海阳帆医药科技有限公司 |
六氢吡咯[3,4-b]吡咯衍生物、其制备方法及其用途
|
|
CN101870671B
(zh)
*
|
2010-06-11 |
2012-06-27 |
漆又毛 |
金刚烷基吡咯烷衍生物及制备和应用
|
|
JP5843855B2
(ja)
|
2010-06-24 |
2016-01-13 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病療法
|
|
IT1400714B1
(it)
|
2010-07-06 |
2013-06-28 |
Chemelectiva S R L |
Processo ed intermedi per la preparazione di un principio attivo.
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
JP5812295B2
(ja)
*
|
2010-08-09 |
2015-11-11 |
塩野義製薬株式会社 |
アミノアダマンタンカルバメート誘導体の製造方法
|
|
HU231050B1
(hu)
|
2010-08-19 |
2020-02-28 |
Egis Gyógyszergyár Nyrt. |
Eljárás gyógyszerhatóanyag előállítására
|
|
MX2013003184A
(es)
|
2010-09-22 |
2013-06-07 |
Arena Pharm Inc |
Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo.
|
|
AR083878A1
(es)
|
2010-11-15 |
2013-03-27 |
Boehringer Ingelheim Int |
Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
|
|
US8877815B2
(en)
|
2010-11-16 |
2014-11-04 |
Novartis Ag |
Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
|
|
US8673974B2
(en)
|
2010-11-16 |
2014-03-18 |
Novartis Ag |
Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
|
|
TR201101809A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ |
Vildagliptin ve glimepirid kombinasyonları.
|
|
TR201010683A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç San. Ve Ti̇c. A.Ş. |
Vildagliptin formülasyonları.
|
|
EP2468268B1
(en)
|
2010-12-21 |
2017-12-13 |
Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi |
Combination composition of vildagliptin and gliclazide
|
|
TR201107482A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç San.Ve Ti̇c.A.Ş. |
Vildagliptin ve gliklazidin iki tabakalı kombinasyon kompozisyonu.
|
|
MX350611B
(es)
|
2011-01-31 |
2017-09-11 |
Cadila Healthcare Ltd |
Tratamiento para la lipodistrofia.
|
|
CN103459382B
(zh)
|
2011-03-02 |
2016-06-29 |
拜奥埃内杰尼克斯公司 |
用于抑制pask的杂环化合物
|
|
US20140018371A1
(en)
|
2011-04-01 |
2014-01-16 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140066369A1
(en)
|
2011-04-19 |
2014-03-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140038889A1
(en)
|
2011-04-22 |
2014-02-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140051714A1
(en)
|
2011-04-22 |
2014-02-20 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
WO2012170702A1
(en)
|
2011-06-08 |
2012-12-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
EP2729468A4
(en)
|
2011-07-05 |
2015-03-18 |
Merck Sharp & Dohme |
Tricyclic heterocycles useful as dipeptidyl peptidase-iv inhibitors
|
|
DK2731947T3
(en)
|
2011-07-15 |
2019-04-23 |
Boehringer Ingelheim Int |
SUBSTITUTED DIMERIC QUINAZOLINE DERIVATIVE, PREPARATION AND USE thereof IN PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF TYPE I AND TYPE II DIABETES
|
|
US20140302150A1
(en)
|
2011-09-07 |
2014-10-09 |
Umit Cifter |
Dpp-iv inhibitor formulations
|
|
EP2572704A1
(en)
|
2011-09-22 |
2013-03-27 |
Sanovel Ilac Sanayi ve Ticaret A.S. |
Orally-Disintegrating Formulations of Vildagliptin
|
|
PL2578208T3
(pl)
|
2011-10-06 |
2014-10-31 |
Sanovel Ilac Sanayi Ve Ticaret As |
Stałe formulacje dawkowane inhibitora DPP-IV
|
|
WO2013055910A1
(en)
|
2011-10-12 |
2013-04-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
ITMI20112224A1
(it)
|
2011-12-06 |
2013-06-07 |
Chemelectiva S R L |
Nuovo processo ed intermedi per la sintesi di vildagliptin
|
|
CN102491928A
(zh)
*
|
2011-12-13 |
2012-06-13 |
临海天宇药业有限公司 |
一种制备(2s)-n-氯乙酰基-2-氰基四氢吡咯的方法
|
|
US9115082B2
(en)
|
2012-01-18 |
2015-08-25 |
Catherine Yang |
Dipeptidyl-peptidase-IV inhibitors for treatment of type 2 diabetes complex with hypertension
|
|
US9073930B2
(en)
|
2012-02-17 |
2015-07-07 |
Merck Sharp & Dohme |
Dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
CN102617434B
(zh)
*
|
2012-03-29 |
2014-07-23 |
中国科学院上海有机化学研究所 |
一锅法制备维达列汀
|
|
WO2013179300A2
(en)
|
2012-05-04 |
2013-12-05 |
Megafine Pharma (P) Ltd. |
A process for the preparation of vildagliptin and its intermediate thereof
|
|
EP2849754B1
(en)
|
2012-05-14 |
2022-09-14 |
Boehringer Ingelheim International GmbH |
Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
|
|
WO2013171167A1
(en)
|
2012-05-14 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
US9315508B2
(en)
|
2012-07-23 |
2016-04-19 |
Merck Sharp & Dohme Corp. |
Treating diabetes with dipeptidyl peptidase-IV inhibitors
|
|
WO2014020462A1
(en)
*
|
2012-08-01 |
2014-02-06 |
Alembic Pharmaceuticals Limited |
Improved process for preparation of vildagliptin intermediate
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
TWI500613B
(zh)
|
2012-10-17 |
2015-09-21 |
Cadila Healthcare Ltd |
新穎之雜環化合物
|
|
WO2014074668A1
(en)
|
2012-11-08 |
2014-05-15 |
Arena Pharmaceuticals, Inc. |
Modulators of gpr119 and the treatment of disorders related thereto
|
|
UY35144A
(es)
|
2012-11-20 |
2014-06-30 |
Novartis Ag |
Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
|
|
CN103922986B
(zh)
*
|
2013-01-16 |
2017-02-15 |
上海彩迩文生化科技有限公司 |
维大列汀及其类似物、中间体及其制备方法和应用
|
|
NZ710574A
(en)
|
2013-02-14 |
2017-11-24 |
Novartis Ag |
Substituted bisphenyl butanoic phosphonic acid derivatives as nep (neutral endopeptidase) inhibitors
|
|
MX346943B
(es)
|
2013-04-22 |
2017-04-06 |
Cadila Healthcare Ltd |
Una nueva composición para esteatosis hepática no alcohólica (nafld).
|
|
EP3004053B1
(en)
|
2013-05-30 |
2021-03-24 |
Cadila Healthcare Limited |
A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
|
|
CN103304502B
(zh)
*
|
2013-06-02 |
2015-03-04 |
张远强 |
一类抗糖尿病化合物、其制备方法和用途
|
|
TW201636015A
(zh)
|
2013-07-05 |
2016-10-16 |
卡地拉保健有限公司 |
協同性組成物
|
|
SG11201600211XA
(en)
|
2013-07-25 |
2016-02-26 |
Novartis Ag |
Cyclic polypeptides for the treatment of heart failure
|
|
IN2013MU02470A
(forum.php)
|
2013-07-25 |
2015-06-26 |
Cadila Healthcare Ltd |
|
|
AP2016009019A0
(en)
|
2013-07-25 |
2016-02-29 |
Novartis Ag |
Bioconjugates of synthetic apelin polypeptides
|
|
US10112898B2
(en)
|
2013-09-06 |
2018-10-30 |
Cadila Healthcare Limited |
Process for the preparation of saroglitazar pharmaceutical salts
|
|
JP6657101B2
(ja)
|
2013-11-05 |
2020-03-04 |
ベン グリオン ユニバーシティ オブ ザ ネガフ リサーチ アンド ディベロップメント オーソリティ |
糖尿病及びそれから生じる疾患合併症の治療のための化合物
|
|
CN103641761A
(zh)
*
|
2013-11-22 |
2014-03-19 |
沈阳化工大学 |
一种维格利汀的制备方法
|
|
WO2015128453A1
(en)
|
2014-02-28 |
2015-09-03 |
Boehringer Ingelheim International Gmbh |
Medical use of a dpp-4 inhibitor
|
|
EP2915528A1
(en)
|
2014-03-06 |
2015-09-09 |
Sanovel Ilac Sanayi ve Ticaret A.S. |
Vildagliptin formulation process under inert gas atmosphere
|
|
CN103992257B
(zh)
*
|
2014-05-16 |
2016-03-30 |
苏州天马精细化学品股份有限公司 |
一种维格列汀粗品的纯化方法
|
|
CN105439873A
(zh)
*
|
2014-08-20 |
2016-03-30 |
天津药物研究院 |
3-羟基-1-金刚烷胺的制备方法
|
|
GB201415598D0
(en)
|
2014-09-03 |
2014-10-15 |
Univ Birmingham |
Elavated Itercranial Pressure Treatment
|
|
CN105884669B
(zh)
*
|
2014-09-15 |
2020-05-15 |
深圳翰宇药业股份有限公司 |
制备取代的(s)-吡咯烷-2-甲腈及维格列汀的方法
|
|
EP4445956A3
(en)
|
2015-01-06 |
2024-12-04 |
Arena Pharmaceuticals, Inc. |
Compound for use in treating conditions related to the s1p1 receptor
|
|
CN104529857B
(zh)
*
|
2015-01-13 |
2016-03-30 |
佛山市赛维斯医药科技有限公司 |
卤代金刚烷酰胺类衍生物、其制备方法和用途
|
|
CN107406490A
(zh)
|
2015-01-23 |
2017-11-28 |
诺华股份有限公司 |
具有改善的半衰期的合成apelin脂肪酸缀合物
|
|
JP2018507914A
(ja)
|
2015-03-09 |
2018-03-22 |
インテクリン・セラピューティクス・インコーポレイテッド |
非アルコール性脂肪肝疾患および／またはリポジストロフィーの処置のための方法
|
|
CN104761456B
(zh)
*
|
2015-03-10 |
2020-04-10 |
上海威智医药科技有限公司 |
3-氨基-1-金刚烷醇的制备方法
|
|
CN104817482B
(zh)
*
|
2015-03-17 |
2017-05-10 |
宁波百思佳医药科技有限公司 |
2‑取代吡咯烷类化合物、制备方法及其在制备维格列汀中的应用
|
|
AU2016284162A1
(en)
|
2015-06-22 |
2018-02-01 |
Arena Pharmaceuticals, Inc. |
Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(Compound1) for use in SIP1 receptor-associated disorders
|
|
WO2017064635A2
(en)
|
2015-10-14 |
2017-04-20 |
Cadila Healthcare Limited |
Pyrrole compound, compositions and process for preparation thereof
|
|
RU2628573C2
(ru)
*
|
2015-11-27 |
2017-08-21 |
Общество с ограниченной ответственностью "Аллель Центр Инновационных Биотехнологий" |
Ингибитор дипептидилпептидазы-4 для лечения сахарного диабета 2-го типа
|
|
BR112018013195A2
(pt)
|
2015-12-28 |
2018-12-11 |
Wockhardt Ltd |
composição farmacêutica osmótica oral de vildagliptina
|
|
CN109310697A
(zh)
|
2016-06-10 |
2019-02-05 |
勃林格殷格翰国际有限公司 |
利格列汀和二甲双胍的组合
|
|
DE102016116130A1
(de)
|
2016-08-30 |
2018-03-01 |
Universität Bielefeld |
Verfahren zur Herstellung chiraler Aminonitrile
|
|
WO2018050892A1
(en)
|
2016-09-16 |
2018-03-22 |
Galenicum Health S.L. |
Vildagliptin pharmaceutical compositions
|
|
JOP20190086A1
(ar)
|
2016-10-21 |
2019-04-18 |
Novartis Ag |
مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
|
|
EP3551180B1
(en)
|
2016-12-09 |
2021-09-29 |
Cadila Healthcare Limited |
Treatment for primary biliary cholangitis
|
|
WO2018162722A1
(en)
|
2017-03-09 |
2018-09-13 |
Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke |
Dpp-4 inhibitors for use in treating bone fractures
|
|
BR112019020485A2
(pt)
|
2017-04-03 |
2020-05-12 |
Coherus Biosciences, Inc. |
Agonista ppary para tratamento de paralisia supranuclear progressiva
|
|
GR1009406B
(el)
|
2017-10-03 |
2018-11-26 |
Φαρματεν Αβεε |
Φαρμακευτικο σκευασμα που περιλαμβανει βιλνταγλιπτινη και μεθοδος για την παρασκευη αυτου
|
|
UY38072A
(es)
|
2018-02-07 |
2019-10-01 |
Novartis Ag |
Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
|
|
KR102622198B1
(ko)
|
2018-03-30 |
2024-01-09 |
한미약품 주식회사 |
빌다글립틴을 함유하는 경구용 고형제제 및 그의 제조 방법
|
|
WO2019236757A1
(en)
|
2018-06-06 |
2019-12-12 |
Arena Pharmaceuticals, Inc. |
Methods of treating conditions related to the s1p1 receptor
|
|
GR1009644B
(el)
|
2018-09-25 |
2019-11-12 |
Φαρματεν Α.Β.Ε.Ε. |
Φαρμακευτικο σκευασμα που περιλαμβανει βιλνταγλιπτινη και μετφορμινη και μεθοδος για την παρασκευη αυτου
|
|
JP2022507958A
(ja)
|
2018-11-27 |
2022-01-18 |
ノバルティス アーゲー |
代謝障害の治療用のプロタンパク質転換酵素サブチリシン／ケキシン９型（ｐｃｓｋ９）阻害薬としての環状四量体化合物
|
|
WO2020110011A1
(en)
|
2018-11-27 |
2020-06-04 |
Novartis Ag |
Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (pcsk9) inhibitors for the treatment of metabolic disorders
|
|
UY38485A
(es)
|
2018-11-27 |
2020-06-30 |
Novartis Ag |
Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación
|
|
JP7461735B2
(ja)
*
|
2019-12-02 |
2024-04-04 |
日本ジェネリック株式会社 |
ビルダグリプチン含有錠剤
|
|
CN113527167B
(zh)
*
|
2020-04-14 |
2024-01-19 |
威智医药股份有限公司 |
一种维格列汀的生产方法
|
|
WO2021234430A1
(en)
|
2020-05-17 |
2021-11-25 |
Lotus International Pte. Ltd. |
Modified release dosage form comprising vildagliptin and process for manufacturing the same
|
|
WO2022003405A1
(en)
|
2020-07-03 |
2022-01-06 |
Savoi Guilherme |
One-pot process to obtain a pyrrolidine-2-carbonitrile intermediate compound and industrial scale telescopic process to prepare (2s)-1-[n-(3-hydroxyadamantan-1-yl)glycyl]-2-pyrrolidinecarbonitrile (vildagliptin) using same
|
|
US20230285576A1
(en)
|
2020-08-05 |
2023-09-14 |
Ellipses Pharma Ltd |
Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor
|
|
US20240174675A1
(en)
*
|
2021-01-21 |
2024-05-30 |
The Scripps Research Institute |
Small molecule regulators of alveolar type 2 cell proliferation for the treatment of pulmonary diseases
|
|
WO2023084449A1
(en)
|
2021-11-12 |
2023-05-19 |
Novartis Ag |
Diaminocyclopentylpyridine derivatives for the treatment of a disease or disorder
|
|
AR127698A1
(es)
|
2021-11-23 |
2024-02-21 |
Novartis Ag |
Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno
|
|
WO2024241229A1
(en)
|
2023-05-24 |
2024-11-28 |
Novartis Ag |
Naphthyridinone derivatives for the treatment of a disease or disorder
|