KR101656237B1 - 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 - Google Patents
표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 Download PDFInfo
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- KR101656237B1 KR101656237B1 KR1020157022593A KR20157022593A KR101656237B1 KR 101656237 B1 KR101656237 B1 KR 101656237B1 KR 1020157022593 A KR1020157022593 A KR 1020157022593A KR 20157022593 A KR20157022593 A KR 20157022593A KR 101656237 B1 KR101656237 B1 KR 101656237B1
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261717324P | 2012-10-23 | 2012-10-23 | |
| US61/717,324 | 2012-10-23 | ||
| US201361803599P | 2013-03-20 | 2013-03-20 | |
| US61/803,599 | 2013-03-20 | ||
| US201361837481P | 2013-06-20 | 2013-06-20 | |
| US61/837,481 | 2013-06-20 | ||
| PCT/KR2013/009488 WO2014065596A1 (en) | 2012-10-23 | 2013-10-23 | Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157013868A Division KR102182847B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20150101477A KR20150101477A (ko) | 2015-09-03 |
| KR101656237B1 true KR101656237B1 (ko) | 2016-09-12 |
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157022593A Active KR101656237B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020157022594A Active KR101706085B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020187006398A Active KR102052286B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020157022592A Active KR101656236B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020157013868A Active KR102182847B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157022594A Active KR101706085B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020187006398A Active KR102052286B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020157022592A Active KR101656236B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
| KR1020157013868A Active KR102182847B1 (ko) | 2012-10-23 | 2013-10-23 | 표적 DNA에 특이적인 가이드 RNA 및 Cas 단백질을 암호화하는 핵산 또는 Cas 단백질을 포함하는, 표적 DNA를 절단하기 위한 조성물 및 이의 용도 |
Country Status (16)
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| EP (12) | EP4397759A3 (enExample) |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180054427A (ko) * | 2016-11-14 | 2018-05-24 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| WO2018117377A1 (ko) * | 2016-12-22 | 2018-06-28 | 주식회사 툴젠 | Fad2 유전자 조작된 올레인산 강화 식물체 및 이의 제조 방법 |
| KR20190038449A (ko) * | 2017-09-29 | 2019-04-08 | 서울대학교산학협력단 | Klotho 유전자 넉아웃 질환모델 동물 및 이의 용도 |
| US11352666B2 (en) | 2014-11-14 | 2022-06-07 | Institute For Basic Science | Method for detecting off-target sites of programmable nucleases in a genome |
| WO2023282688A1 (ko) | 2021-07-09 | 2023-01-12 | 주식회사 툴젠 | 산화스트레스 저항성을 갖는 중간엽 줄기세포, 이의 제조방법 및 용도 |
| WO2023008933A1 (ko) | 2021-07-29 | 2023-02-02 | 주식회사 툴젠 | 혈액 적합성을 갖는 중간엽 줄기세포, 이의 제조방법 및 용도 |
| WO2023167575A1 (ko) | 2022-03-04 | 2023-09-07 | 주식회사 툴젠 | 저면역원성 줄기세포, 줄기세포로부터 분화되거나 유래된 저면역원성 세포 및 이의 제조방법 |
| WO2023219434A1 (ko) | 2022-05-13 | 2023-11-16 | 주식회사 툴젠 | 혈액 적합성을 갖는 혈관 내 이식용 세포, 이의 제조방법 및 용도 |
| US12509697B2 (en) | 2023-11-29 | 2025-12-30 | Toolgen Incorporated | Oleic acid-enriched plant body having genetically modified FAD2 and production method thereof |
Families Citing this family (436)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10030245B2 (en) | 2011-03-23 | 2018-07-24 | E I Du Pont De Nemours And Company | Methods for producing a complex transgenic trait locus |
| EP2734621B1 (en) | 2011-07-22 | 2019-09-04 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| EP2766498B1 (en) | 2011-10-14 | 2019-06-19 | President and Fellows of Harvard College | Sequencing by structure assembly |
| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
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| US11352666B2 (en) | 2014-11-14 | 2022-06-07 | Institute For Basic Science | Method for detecting off-target sites of programmable nucleases in a genome |
| KR102621539B1 (ko) * | 2016-11-14 | 2024-01-09 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| WO2018088694A3 (ko) * | 2016-11-14 | 2018-08-09 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| US12331086B2 (en) | 2016-11-14 | 2025-06-17 | Toolgen Incorporated | Artificially engineered SC function control system |
| KR20180054427A (ko) * | 2016-11-14 | 2018-05-24 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
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| KR20220122592A (ko) * | 2016-11-14 | 2022-09-02 | 주식회사 툴젠 | 인위적으로 조작된 sc 기능 조절 시스템 |
| WO2018117377A1 (ko) * | 2016-12-22 | 2018-06-28 | 주식회사 툴젠 | Fad2 유전자 조작된 올레인산 강화 식물체 및 이의 제조 방법 |
| US12286635B2 (en) | 2016-12-22 | 2025-04-29 | Toolgen Incorporated | Oleic acid-enriched plant body having genetically modified FAD2 and production method thereof |
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| WO2023008933A1 (ko) | 2021-07-29 | 2023-02-02 | 주식회사 툴젠 | 혈액 적합성을 갖는 중간엽 줄기세포, 이의 제조방법 및 용도 |
| WO2023167575A1 (ko) | 2022-03-04 | 2023-09-07 | 주식회사 툴젠 | 저면역원성 줄기세포, 줄기세포로부터 분화되거나 유래된 저면역원성 세포 및 이의 제조방법 |
| WO2023219434A1 (ko) | 2022-05-13 | 2023-11-16 | 주식회사 툴젠 | 혈액 적합성을 갖는 혈관 내 이식용 세포, 이의 제조방법 및 용도 |
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