KR101235094B1 - 섬유성 질환의 치료 또는 예방용 인돌리논 유도체 - Google Patents
섬유성 질환의 치료 또는 예방용 인돌리논 유도체 Download PDFInfo
- Publication number
- KR101235094B1 KR101235094B1 KR1020077017058A KR20077017058A KR101235094B1 KR 101235094 B1 KR101235094 B1 KR 101235094B1 KR 1020077017058 A KR1020077017058 A KR 1020077017058A KR 20077017058 A KR20077017058 A KR 20077017058A KR 101235094 B1 KR101235094 B1 KR 101235094B1
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- KR
- South Korea
- Prior art keywords
- phenyl
- methylene
- indolinone
- anilino
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 0 COC(C(C=C1NC2=O)=CC[C@]1C2=C(*)Nc1ccc(*)cc1)=O Chemical compound COC(C(C=C1NC2=O)=CC[C@]1C2=C(*)Nc1ccc(*)cc1)=O 0.000 description 1
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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- C—CHEMISTRY; METALLURGY
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04030770.4 | 2004-12-24 | ||
| EP04030770 | 2004-12-24 | ||
| PCT/EP2005/057002 WO2006067165A2 (en) | 2004-12-24 | 2005-12-21 | Indolidone derivatives for the treatment or prevention of fibrotic diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20070090038A KR20070090038A (ko) | 2007-09-04 |
| KR101235094B1 true KR101235094B1 (ko) | 2013-02-20 |
Family
ID=36602118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077017058A Expired - Lifetime KR101235094B1 (ko) | 2004-12-24 | 2005-12-21 | 섬유성 질환의 치료 또는 예방용 인돌리논 유도체 |
Country Status (32)
| Country | Link |
|---|---|
| US (7) | US20060142373A1 (enExample) |
| EP (4) | EP3643309B1 (enExample) |
| JP (1) | JP5122976B2 (enExample) |
| KR (1) | KR101235094B1 (enExample) |
| CN (1) | CN101087605B (enExample) |
| AR (1) | AR052177A1 (enExample) |
| AU (1) | AU2005318126B2 (enExample) |
| BE (1) | BE2015C038I2 (enExample) |
| CA (1) | CA2591083C (enExample) |
| CY (3) | CY1113766T1 (enExample) |
| DK (2) | DK1830843T3 (enExample) |
| EA (1) | EA015011B1 (enExample) |
| ES (2) | ES2797546T3 (enExample) |
| FR (1) | FR15C0046I2 (enExample) |
| HR (1) | HRP20130059T1 (enExample) |
| HU (2) | HUE050998T2 (enExample) |
| IL (1) | IL184125A (enExample) |
| LT (2) | LT2878297T (enExample) |
| LU (1) | LU92762I2 (enExample) |
| ME (1) | ME01493B (enExample) |
| MY (1) | MY148108A (enExample) |
| NO (4) | NO339784B1 (enExample) |
| NZ (1) | NZ556681A (enExample) |
| PE (1) | PE20060777A1 (enExample) |
| PL (2) | PL2878297T3 (enExample) |
| PT (2) | PT1830843E (enExample) |
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