KR100878334B1 - 대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰유전자 - Google Patents

대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰유전자 Download PDF

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KR100878334B1
KR100878334B1 KR1020067022699A KR20067022699A KR100878334B1 KR 100878334 B1 KR100878334 B1 KR 100878334B1 KR 1020067022699 A KR1020067022699 A KR 1020067022699A KR 20067022699 A KR20067022699 A KR 20067022699A KR 100878334 B1 KR100878334 B1 KR 100878334B1
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마르쿠스 폼페유스
부르크하르트 크뢰거
하르트비크 슈뢰더
오스카르 첼더
그레고르 하베르하우어
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Abstract

본 발명은 코리네박테리움 글루타미쿰 (Corynebacterium glutamicum)으로부터의 신규 MP 단백질을 코딩하는, MP 핵산 분자로 명명된 단리된 핵산 분자를 기재한다. 또한, 본 발명은 안티센스 핵산 분자, MP 핵산 분자를 함유하는 재조합 발현 벡터, 및 상기 발현 벡터가 도입된 숙주 세포를 제공한다. 또한, 본 발명은 단리된 MP 단백질, 돌연변이된 MP 단백질, 융합 단백질, 항원성 펩티드, 및 코리네박테리움 글루타미쿰에서 MP 유전자의 유전공학적 조작을 기초로 하여 상기 생물로부터 원하는 화합물의 생성을 개선시키는 방법을 제공한다.
코리네박테리움 글루타미쿰, MP 단백질, 핵산 분자, 재조합 발현 벡터, 숙주 세포

Description

대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰 유전자 {Corynebacterium Glutamicum Genes Encoding Metabolic Pathway Proteins}
관련 출원
본 출원은 미국 임시 특허 출원 제60/141031호 (1999년 6월 25일 출원), 미국 임시 특허 출원 제60/142101호 (1999년 7월 2일 출원), 미국 임시 특허 출원 제60/148613호 (1999년 8월 12일 출원), 및 또한 미국 임시 특허 출원 제60/187970호 (2000년 3월 9일 출원)에 대한 우선권을 청구한다. 또한, 본 출원은 독일 특허 출원 제19930476.9호 (1999년 7월 1일 출원), 독일 특허 출원 제19931415.2호 (1999년 7월 8일 출원), 독일 특허 출원 제19931418.7호 (1999년 7월 8일 출원), 독일 특허 출원 제19931419.5호 (1999년 7월 8일 출원), 독일 특허 출원 제19931420.9호 (1999년 7월 8일 출원), 독일 특허 출원 제19931424.1호 (1999년 7월 8일 출원), 독일 특허 출원 제19931428.4호 (1999년 7월 8일 출원), 독일 특허 출원 제19931434.9호 (1999년 7월 8일 출원), 독일 특허 출원 제19931435.7호 (1999년 7월 8일 출원), 독일 특허 출원 제19931443.8호 (1999년 7월 8일 출원), 독일 특허 출원 제19931453.5호 (1999년 7월 8일 출원), 독일 특허 출원 제19931457.8호 (1999 년 7월 8일 출원), 독일 특허 출원 제19931465.9호 (1999년 7월 8일 출원), 독일 특허 출원 제19931478.0호 (1999년 7월 8일 출원), 독일 특허 출원 제19931510.8호 (1999년 7월 8일 출원), 독일 특허 출원 제19931541.8호 (1999년 7월 8일 출원), 독일 특허 출원 제19931573.6호 (1999년 7월 8일 출원), 독일 특허 출원 제19931592.2호 (1999년 7월 8일 출원), 독일 특허 출원 제19931632.5호 (1999년 7월 8일 출원), 1999년 독일 특허 출원 제19931634.1호 (1999년 7월 8일 출원), 독일 특허 출원 제19931636.8호 (1999년 7월 8일 출원), 독일 특허 출원 제19932125.6호 (1999년 7월 9일 출원), 독일 특허 출원 제19932126.4호 (1999년 7월 9일 출원), 독일 특허 출원 제19932130.2호 (1999년 7월 9일 출원), 독일 특허 출원 제19932186.8호 (1999년 7월 9일 출원), 독일 특허 출원 제19932206.6호 (1999년 7월 9일 출원), 독일 특허 출원 제19932227.9호 (1999년 7월 9일 출원), 독일 특허 출원 제19932228.7호 (1999년 7월 9일 출원), 독일 특허 출원 제19932229.5호 (1999년 7월 9일 출원), 독일 특허 출원 제19932230.9호 (1999년 7월 9일 출원), 독일 특허 출원 제19932922.2호 (1999년 7월 14일 출원), 독일 특허 출원 제19932926.5호 (1999년 7월 14일 출원), 독일 특허 출원 제19932928.1호 (1999년 7월 14일 출원), 독일 특허 출원 제19933004.2호 (1999년 7월 14일 출원), 독일 특허 출원 제19933005.0호 (1999년 7월 14일 출원), 독일 특허 출원 제19933006.9호 (1999년 7월 14일 출원), 독일 특허 출원 제19940764.9호 (1999년 8월 27일 출원), 독일 특허 출원 제19940765.7호 (1999년 8월 27일 출원), 독일 특허 출원 제19940766.5호 (1999년 8월 27일 출원), 독일 특허 출원 제19940832.7호 (1999년 8월 27일 출원), 독일 특허 출원 제19941378.9호 (1999년 8월 31일 출원), 독일 특허 출원 제19941379.7호 (1999년 8월 31일 출원), 독일 특허 출원 제19941380.0호 (1999년 8월 31일 출원), 독일 특허 출원 제19941394.0호 (1999년 8월 31일 출원), 독일 특허 출원 제19941396.7호 (1999년 8월 31일 출원), 독일 특허 출원 제19942076.9호 (1999년 9월 3일 출원), 독일 특허 출원 제19942077.7호 (1999년 9월 3일 출원), 독일 특허 출원 제19942079.3호 (1999년 9월 3일 출원), 독일 특허 출원 제19942086.6호 (1999년 9월 3일 출원), 독일 특허 출원 제19942087.4호 (1999년 9월 3일 출원), 독일 특허 출원 제19942088.2호 (1999년 9월 3일 출원), 독일 특허 출원 제19942095.5호 (1999년 9월 3일 출원), 독일 특허 출원 제19942124.2호 (1999년 9월 3일 출원), 및 독일 특허 출원 제19942129.3호 (1999년 9월 3일 출원)에 대한 우선권을 청구한다. 상기 언급한 모든 출원의 전체 내용은 본 명세서에 명백히 포함되는 것으로 한다.
세포에서의 자연 발생적 대사 과정의 특정 생성물 및 부산물은 식품, 사료, 화장품 및 제약 산업을 비롯한 다양한 산업 분야에 사용된다. 총체적으로 "정밀 화학물질"로 언급되는 이들 분자로는 유기산, 단백질생성 및 비-단백질생성 아미노산, 뉴클레오티드 및 뉴클레오시드, 지질 및 지방산, 디올, 탄수화물, 방향족 화합물, 비타민 및 보조인자, 및 효소 등이 있다. 이들의 생성은 원하는 특정 분자를 대량으로 생산하고 분비하도록 개발된 박테리아의 대규모 배양을 통해 가장 편리하게 수행된다. 이러한 목적에 특히 유용한 생물은 그람 양성의 비병원성 박테리아 인 코리네박테리움 글루타미쿰 (Corynebacterium Glutamicum)이다. 균주 선별을 통해, 일련의 바람직한 화합물을 생산하는 다수의 돌연변이 균주가 개발되어 있다. 그러나, 특정 분자의 생산을 위해 개선된 균주의 선별은 시간 소모적이고 어려운 과정이다.
본 발명은 다양한 용도를 갖는 신규 박테리아 핵산 분자를 제공한다. 상기 용도로는 코리네박테리움 글루타미쿰의 게놈을 맵핑하기 위한 기준점 및 형질전환용 마커로서 정밀 화학물질의 생산에 사용될 수 있는 미생물의 확인, 코리네박테리움 글루타미쿰 또는 관련 박테리아에서의 정밀 화학물질의 생산 조절, 및 코리네박테리움 글루타미쿰 또는 관련 박테리아의 타이핑 또는 확인 등이 있다. 이들 신규 핵산 분자는 본원에서 대사 경로 (MP) 단백질로 언급되는 단백질을 코딩한다.
코리네박테리움 글루타미쿰은 다양한 정밀 화학물질의 대량 생산, 탄화수소의 분해 (예를 들어, 광유 스필) 및 테르페노이드의 산화를 위해 공업적으로 통상 사용되는 그람 양성 호기성 박테리아이다. 따라서, 본 발명의 MP 핵산 분자는 발효 공정 등에 의한 정밀 화학물질 생산에 이용할 수 있는 미생물 확인에 사용할 수 있다. 본 발명의 MP 핵산의 발현 조절 또는 본 발명의 MP 핵산 분자의 서열 변형을 이용하여 미생물로부터의 정밀 화학물질 하나 이상의 생산을 조절할 수 있다 (예를 들어, 코리네박테리움 또는 브레비박테리움 종으로부터의 정밀 화학물질 하나 이상의 수율 또는 생산성을 개선하기 위함).
또한, 본 발명의 MP 핵산은 코리네박테리움 글루타미쿰 또는 그와 밀접하게 관련된 것일 수 있는 생물을 확인하거나, 혼합된 미생물 집단에서 코리네박테리움 글루타미쿰 또는 그와 밀접하게 관련된 미생물의 존재 여부를 확인하는 데 사용할 수도 있다. 본 발명은 단일 또는 혼합된 미생물 집단의 배양물 중의 추출 게놈 DNA를 엄격 조건하에 코리네박테리움 글루타미쿰에 고유한 코리네박테리움 글루타미쿰 유전자 영역에 걸쳐 있는 프로브를 사용하여 탐침함으로써 이 생물의 존재 여부를 확인할 수 있는 다수의 코리네박테리움 글루타미쿰 유전자의 핵산 서열을 제공한다. 코리네박테리움 글루타미쿰 그 자체는 인간에게 병원성이 아니지만, 코리네박테리움 디프테리아 (Corynebacterium diphtheriae) (디프테리아의 병원체)와 같, 인간에게 병원성인 종과 관련되어 있고, 이러한 생물의 검출은 임상적으로 상당히 중요하다.
본 발명의 MP 핵산 분자는 코리네박테리움 글루타미쿰의 게놈 또는 관련 생물의 게놈을 맵핑하기 위한 기준점으로도 기능할 수 있다. 유사하게, 이들 분자, 그의 변이체 또는 일부는 유전공학적으로 조작된 코리네박테리움 또는 브레비박테리움 종을 위한 마커로 기능할 수 있다.
본 발명의 신규 핵산 분자에 의해 코딩되는 MP 단백질은 예를 들어, 아미노산, 비타민, 보조인자, 영양제 (nutraceutical), 뉴클레오티드, 뉴클레오시드, 및 트레할로스 등의 특정 정밀 화학물질의 대사에 관여하는 효소 단계를 수행할 수 있다. 미국 특허 제4,649,119호 [Sinskey et al.]에 개시된 클로닝 벡터와 같은 코리네박테리움 글루타미쿰에 사용하기 위한 클로닝 벡터, 및 코리네박테리움 글루타 미쿰 및 관련된 브레비박테리움 종 (예를 들어, 락토페르멘툼)의 유전 조작 기술 (문헌 [Yoshihama et al, J. Bacteriol. 162: 591-597 (1985)], 문헌 [Katsumata et al., J. Bacteriol. 159: 306-311 (1984)], 및 문헌 [Santamaria et al., J. Gen. Microbiol. 130: 22372246 (1984)])을 이용하여, 본 발명의 핵산 분자로 이 생물을 유전공학적 조작하여, 이 생물이 1종 이상의 정밀 화학물질의 보다 효율적 생산자가 되도록 할 수 있다.
정밀 화학물질의 생산 효율 또는 생산성 개선은 본 발명의 유전자 조작의 직접적인 효과에 기인하거나, 이러한 조작의 간접적인 효과에 기인할 수 있다. 구체적으로, 코리네박테리움 글루타미쿰에서의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드 및 트레할로스 대사 경로 변경은 이 생물에서 1종 이상의 상기 원하는 화합물의 전반적인 생산성에 직접적인 영향을 미칠 수 있다. 예를 들어, 리신 생합성 경로 단백질의 활성을 최적화시키거나 리신 분해 경로 단백질의 활성을 감소시키면, 이 유전공학적으로 조작된 생물로부터의 리신 생산 효율 또는 수율을 증가시킬 수 있다. 이러한 대사 경로에 관여하는 단백질들의 변경은 원하는 정밀 화학물질의 생산 효율 또는 수율에 간접적인 효과를 미칠 수도 있다. 예를 들어, 원하는 분자의 생산에 필요한 중간체에 대한 경쟁 반응을 없애거나, 원하는 화합물의 특정 중간체 생산에 필요한 경로를 최적화할 수 있다. 또한, 예를 들어, 아미노산, 비타민, 또는 뉴클레오티드의 생합성 또는 분해를 조절하여, 미생물이 빠르게 성장하고 빠르게 분열할 수 있도록 이 미생물의 전반적인 능력을 증가시켜 배양물 중의 미생물 개수 및(또는) 생산력이 증가되도록 한다면, 원하는 정밀 화학물질의 가능한 수율을 증가시킬 수 있다.
본 발명의 핵산 또는 단백질 분자를 이용하여 코리네박테리움 글루타미쿰으로부터 1종 이상의 원하는 정밀 화학물질의 생산 효율 또는 생산성을 직접 개선시킬 수 있다. 당업계에 공지된 재조합 유전 기술을 이용하여, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스에 관한 본 발명의 생합성 또는 분해 효소 1종 이상을 조작하여, 그 기능을 조절할 수 있다. 예를 들면, 생합성 효소의 효율을 개선시키거나, 이 효소의 알로스테릭 제어 영역을 파괴하여 화합물 생산의 피드백 억제가 저해되도록 할 수 있다. 유사하게, 치환, 결실, 또는 부가에 의해 분해 효소를 결실시키거나 변형시켜, 세포의 생존력을 손상시키지 않고 원하는 화합물에 대한 이의 분해 활성이 감소되게 할 수 있다. 각 경우에서, 원하는 정밀 화학물질 생산에 관한 전반적인 수율 또는 생산 속도가 증가될 수 있다.
또한, 본 발명의 단백질 및 핵산 분자에서의 이러한 변경은 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 및 트레할로스 뿐 아니라, 간접 메카니즘을 통해 다른 정밀 화학물질의 생산도 개선시킬 수 있다. 임의의 화합물 대사는 세포내 다른 생합성 및 분해 경로와 반드시 얽혀있고, 한 경로에 필요한 보조인자, 중간체 또는 기질은 이러한 다른 경로에 의해 공급되거나 제한되는 것으로 보인다. 그러므로, 본 발명의 단백질 1종 이상의 활성을 조절하여, 다른 정밀 화학적 생합성 또는 분해 경로의 활성 효율 또는 생산성에 영향을 줄 수 있다. 예를 들어, 아미노산은 모든 단백질의 구조 단위로 기능하지만, 세포내에서는 단백질 합성을 제한하는 수준으로 존재한다; 그러므로, 세포내에서 아미노산 1종 이상의 수율 또는 생산 효율을 증가시켜, 생합성 단백질 또는 분해 단백질 등의 단백질이 더욱 쉽게 합성되도록 할 수 있다. 유사하게, 대사 경로 효소의 변경으로 특정 부반응이 더욱 또는 덜 일어나게 되어, 원하는 정밀 화학물질의 생산에 중간체 또는 기질로 이용되는 화합물 1종 이상의 과잉생산 또는 생산부족을 초래할 수 있다.
본 발명은 아미노산, 비타민, 보조인자, 뉴클레오티드 및 뉴클레오시드, 또는 트레할로스 등 세포의 정상적인 기능에 중요한 분자들의 대사에 관여하는 효소 단계 등을 수행할 수 있으며, 본원에서 대사 경로 (MP) 단백질로 언급되는 단백질을 코딩하는 신규 핵산 분자를 제공한다. MP 단백질을 코딩하는 핵산 분자는 본원에서 MP 핵산 분자로 언급된다. 바람직한 실시양태에서, MP 단백질은 다음 중 1종 이상의 대사와 관련된 효소 단계를 수행한다: 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 및 트레할로스. 이러한 단백질의 예로는 표 1에 기재된 유전자에 의해 코딩되는 단백질을 들 수 있다.
따라서, 본 발명의 한 측면은 MP 단백질 또는 생물학적으로 활성인 그의 일부를 코딩하는 뉴클레오티드 서열을 포함하는 단리된 핵산 분자 (예를 들어, cDNA, DNA 또는 RNA) 뿐만 아니라 MP 코딩 핵산 (예를 들어, DNA 또는 mRNA)의 검출 또는 증폭을 위한 프라이머 또는 혼성화 프로브로서 적합한 핵산 단편에 관한 것이다. 특히 바람직한 실시양태에서, 단리된 핵산 분자는 서열목록에서 홀수 서열 번호로 기재된 뉴클레오티드 서열 (예를 들어, 서열 1, 서열 3, 서열 5, 서열 7....) 중 하나, 또는 이들 뉴클레오티드 서열 중 하나의 코딩 영역 또는 그의 상보체를 포함 한다. 특히 바람직한 다른 실시양태에서, 본 발명의 단리된 핵산 분자는 서열목록에서 홀수 서열 번호 (예를 들어, 서열 1, 서열 3, 서열 5, 서열 7....)로 기재된 뉴클레오티드 서열 또는 그의 일부와 혼성화하거나, 약 50% 이상, 바람직하게는 약 60% 이상, 더욱 바람직하게는 약 70%, 80% 또는 90% 이상, 훨씬 더욱 바람직하게는 약 95%, 96%, 97%, 98%, 99% 이상 또는 그 이상의 상동성이 있는 뉴클레오티드 서열을 포함한다. 다른 바람직한 실시양태에서, 단리된 핵산 분자는 서열목록에서 짝수 서열 번호 (예를 들어, 서열 2, 서열 4, 서열 6, 서열 8....)로 기재된 아미노산 서열 중 하나를 코딩한다. 본 발명의 바람직한 MP 단백질은 본원에 기재된 MP 활성 중 적어도 하나를 갖는 것도 바람직하다.
다른 실시양태에서, 단리된 핵산 분자는 단백질 또는 그의 일부를 코딩하는데, 여기서 상기 단백질 또는 그의 일부는 본 발명의 아미노산 서열과 충분한 상동성이 있는 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호를 갖는 서열), 예를 들어, 상기 단백질 또는 그의 일부가 MP 활성을 유지할 수 있을 만큼 본 발명의 아미노산 서열과 충분한 상동성이 있는 아미노산 서열을 포함한다. 바람직하게는, 상기 핵산 분자에 의해 코딩되는 단백질 또는 그의 일부는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 효소 반응의 수행력을 유지한다. 한 실시양태에서, 상기 핵산 분자에 의해 코딩되는 단백질은 본 발명의 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호를 갖는 서열로부터 선택된 전체 아미노산 서열)과 약 50% 이상, 바람직하게는 약 60% 이상, 더욱 바람직하게는 약 70%, 80% 또는 90% 이상, 가장 바람직하게는 약 95 %, 96%, 97%, 98% 또는 99% 이상, 또는 그 이상의 상동성이 있다. 다른 바람직한 실시양태에서, 상기 단백질은 본 발명의 전체 아미노산 서열 (서열목록 중의 상응하는 홀수 서열 번호 (예를 들어, 서열 1, 서열 3, 서열 5, 서열 7....)로 나타낸 오픈 리딩 프레임에 의해 코딩됨)과 실질적으로 상동성이 있는 전장의 코리네박테리움 글루타미쿰 단백질이다.
다른 바람직한 실시양태에서, 단리된 핵산 분자는 코리네박테리움 글루타미쿰으로부터 유래하고, 본 발명의 아미노산 서열 중 하나 (예를 들어, 서열목록에서 짝수 서열 번호 중 하나의 서열)와 약 50% 이상 또는 그 이상의 상동성이 있으며 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 반응을 촉매할 수 있거나 표 1에 기재된 활성 중 하나 이상을 갖는 생물학적 활성 도메인을 포함하며, 이종 폴리펩티드 또는 조절 영역을 코딩하는 이종 핵산 서열도 포함하는 단백질 (예를 들어, MP 융합 단백질)을 코딩한다.
다른 실시양태에서, 단리된 핵산 분자는 그 길이가 뉴클레오티드 15개 이상이고 본 발명의 뉴클레오티드 서열 (예를 들어, 서열목록에서 홀수 서열 번호)을 포함하는 핵산 분자와 엄격 조건하에 혼성화한다. 바람직하게는, 단리된 핵산 분자는 자연 발생 핵산 분자에 상응한다. 더욱 바람직하게는, 단리된 핵산은 코리네박테리움 글루타미쿰의 MP 단백질 또는 생물학적으로 활성인 그의 일부를 코딩한다.
본 발명의 다른 측면은 본 발명의 핵산 분자를 포함하는 벡터, 예를 들어, 재조합 벡터, 및 이러한 벡터가 도입된 숙주 세포에 관한 것이다. 한 실시양태에 서, 상기 숙주 세포는 이 숙주 세포를 적당한 배지에서 배양하여 MP 단백질을 생산하는데 사용된다. 이어서, MP 단백질을 배지 또는 숙주 세포로부터 단리할 수 있다.
본 발명의 다른 측면은 MP 유전자가 도입되거나 변경되어 유전적으로 변경된 미생물에 관한 것이다. 한 실시양태에서, 미생물의 게놈은 야생형 또는 돌연변이된 MP 서열을 코딩하는 본 발명의 핵산 분자를 트랜스진으로서 도입함으로써 변경된다. 다른 실시양태에서, 미생물 게놈 내의 내인성 MP 유전자는 변경된 MP 유전자와의 상동성 재조합에 의해 변경되는데, 예를 들면 기능적으로 파괴된다. 다른 실시양태에서, 미생물 내의 내인성 MP 유전자 또는 도입된 MP 유전자는 하나 이상의 점 돌연변이, 결실 또는 역위에 의해 변경되었지만, 여전히 기능성 MP 단백질을 코딩한다. 다른 실시양태에서, 미생물에 있는 MP 유전자의 하나 이상의 조절 영역 (예를 들어, 프로모터, 리프레서 (repressor) 또는 인듀서 (inducer))를 (예를 들어, 결실, 트런케이션 (truncation), 역위 또는 점 돌연변이에 의해) 변경시켜 MP 유전자의 발현을 조절한다. 바람직한 실시양태에서, 상기 미생물은 코리네박테리움 또는 브레비박테리움 속에 포함되는데, 코리네박테리움 글루타미쿰인 것이 특히 바람직하다. 바람직한 실시양태에서, 상기 미생물은 아미노산, 특히 바람직하게는 리신과 같은 원하는 화합물의 생산에도 사용된다.
다른 측면에서, 본 발명은 한 대상체에서 코리네박테리움 디프테리아의 존재 여부 또는 활성을 확인하는 방법을 제공한다. 이 방법은 한 대상체에서 본 발명의 핵산 또는 아미노산 서열 (예를 들어, 서열목록에서 서열 1 내지 1156으로 기재된 서열)을 하나 이상 검출하는 것을 포함하므로, 상기 대상체에서의 코리네박테리움 디프테리아의 존재 여부 또는 활성을 검출할 수 있다.
본 발명의 다른 측면은 단리된 MP 단백질 또는 그의 일부, 예를 들어, 그의 생물학적 활성 부위에 관한 것이다. 바람직한 실시양태에서, 단리된 MP 단백질 또는 그의 일부는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스의 대사 경로 중 하나 이상에 관여하는 효소 반응을 촉매할 수 있다. 다른 바람직한 실시양태에서, 단리된 MP 단백질 또는 그의 일부는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스의 대사 경로 중 하나 이상에 관여하는 효소 반응을 촉매할 수 있는 능력을 유지할 수 있을 만큼 본 발명의 아미노산 서열 (서열목록에서 짝수 서열 번호)과 충분한 상동성이 있다.
본 발명은 MP 단백질의 단리된 제제를 제공한다. 바람직한 실시양태에서, MP 단백질은 본 발명의 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호)을 포함한다. 다른 바람직한 실시양태에서, 본 발명은 본 발명의 전체 아미노산 서열 (서열목록에서 짝수 서열 번호)과 실질적으로 상동성이 있는 단리된 전장 단백질 (서열목록에서 상응하는 홀수 서열 번호에 기재된 오픈 리딩 프레임에 의해 코딩됨)에 관한 것이다. 다른 실시양태에서, 상기 단백질은 본 발명의 전체 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호)과 약 50% 이상, 바람직하게는 약 60% 이상, 더욱 바람직하게는 약 70%, 80% 또는 90% 이상, 가장 바람직하게는 약 95%, 약 96%, 약 97%, 약 98% 또는 약 99% 이상, 또는 그 이상의 상동성이 있다. 다른 실시양태에서, 단리된 MP 단백질은 본 발명의 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호) 중 하나와 약 50% 이상 또는 그 이상의 상동성이 있는 아미노산 서열을 포함하고, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 효소 반응을 촉매할 수 있거나, 표 1에 기재된 하나 이상의 활성을 갖는다.
별법으로, 단리된 MP 단백질은 서열목록에 기재된 짝수 서열 번호 중 하나의 뉴클레오티드 서열과 혼성화하거나, 예를 들어, 엄격 조건하에서 혼성화하거나, 약 50% 이상, 바람직하게는 약 60% 이상, 더욱 바람직하게는 약 70%, 80% 또는 90% 이상, 가장 바람직하게는 약 95%, 약 96%, 약 97%, 약 98% 또는 약 99% 이상, 또는 그 이상의 상동성이 있는 뉴클레오티드 서열에 의해 코딩되는 아미노산 서열을 포함할 수 있다. 또한, MP 단백질의 바람직한 형태가 본원에 기재된 MP 생물활성 하나 이상을 갖는 것이 바람직하다.
MP 폴리펩티드 또는 그의 생물학적 활성 부위를 MP 폴리펩티드가 아닌 폴리펩티드와 작동가능하게 결합하여 융합 단백질을 형성할 수 있다. 바람직한 실시양태에서, 이 융합 단백질의 활성은 MP 단백질만의 활성과 다르다. 다른 바람직한 실시양태에서, 이 융합 단백질이 코리네박테리움 글루타미쿰의 아미노산, 비타민, 보조인자, 영양제 대사 경로에 도입되는 경우, 이 융합 단백질은 코리네박테리움 글루타미쿰로부터 원하는 정밀 화학물질의 생산 효율 및(또는) 수율을 증가시킨다. 특히 바람직한 실시양태에서, 이 융합 단백질을 숙주 세포의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로에 도입 시켜 숙주 세포로부터 원하는 화합물이 생산되는 것을 조절한다.
다른 측면에서, 본 발명은 MP 단백질 그 자체, 또는 이 MP 단백질의 기질이나 결합 파트너와 상호작용하거나 본 발명의 MP 핵산 분자의 전사 또는 번역을 조절함으로써 MP 단백질의 활성을 조절하는 분자의 스크리닝 방법을 제공한다.
본 발명의 다른 측면은 정밀 화학물질의 제조 방법에 관한 것이다. 이 방법은 본 발명의 MP 핵산 분자의 발현을 지시하는 벡터를 함유하는 세포를 배양하여 정밀 화학물질을 생산하는 것을 포함한다. 바람직한 실시양태에서, 이 방법은 MP 핵산의 발현을 지시하는 벡터로 세포를 형질감염시켜 상기 벡터를 함유하는 세포를 수득하는 단계를 추가로 포함한다. 다른 바람직한 실시양태에서, 이 방법은 배양물로부터 정밀 화학물질을 회수하는 단계를 추가로 포함한다. 특히 바람직한 실시양태에서, 상기 세포는 코리네박테리움 또는 브레비박테리움 속에 속하는 것이거나, 표 3에 기재된 균주로부터 선택된다.
본 발명의 다른 측면은 미생물로부터 분자가 생산되는 것을 조절하는 방법에 관한 것이다. 이러한 방법은 MP 단백질 활성 또는 MP 핵산 발현을 조절하는 작용제와 세포를 접촉시켰을 때의 세포 관련 활성이 상기 작용제의 부재 하에서의 상기 활성에 대해 변경되도록 하는 것을 포함한다. 바람직한 실시양태에서, 코리네박테리움 글루타미쿰의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 하나 이상을 조절하여, 이 미생물에 의한 원하는 정밀 화학물질의 생산 속도 또는 수율을 개선시킨다. MP 단백질 활성을 조절하는 작용제는 MP 단백질 활성 또는 MP 핵산 발현을 자극하는 작용제일 수 있다. MP 단 백질 활성 또는 MP 핵산 발현을 자극하는 작용제의 예로는 소분자, 활성 MP 단백질, 및 세포에 도입된 MP 단백질을 코딩하는 핵산이 있다. MP 활성 또는 발현을 억제하는 물질의 예로는 소분자 및 안티센스 MP 핵산 분자 등이 있다.
본 발명의 다른 측면은 야생형 또는 돌연변이 MP 유전자가 세포내에서 별개의 플라스미드 상에 유지되거나 숙주 세포의 게놈 내로 통합되도록 이 유전자를 세포에 도입하는 것을 포함하는, 세포로부터의 원하는 화합물의 수율을 조절하는 방법에 관한 것이다. 게놈 내로 통합될 때, 이러한 통합은 무작위적일 수도 있고 도입된 카피가 천연 유전자를 대체하도록하는 상동성 재조합에 의해 일어날 수도 있는데, 이러한 통합에 의해 세포로부터의 원하는 화합물의 생산이 조절된다. 바람직한 실시양태에서, 상기 수율은 증가한다. 다른 바람직한 실시양태에서, 상기 화학물질은 정밀 화학물질이다. 특히 바람직한 실시양태에서, 상기 정밀 화학물질은 아미노산이다. 특히 바람직한 실시양태에서, 상기 아미노산은 L-리신이다.
본 발명은 코리네박테리움 글루타미쿰의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 및 트레할로스 대사 경로에 관여하는 MP 핵산 및 단백질 분자를 제공한다. 본 발명의 분자를 이용하여 코리네박테리움 글루타미쿰 등의 미생물로부터의 정밀 화학물질 생산을 직접 조절 (예를 들어, 리신 생합성 단백질의 활성 조절은 이 생물로부터의 리신 생산 효율 및 생산성에 직접적인 영향을 준다)할 수 있거나, 역시 원하는 화합물의 생산 효율 또는 수율의 증가를 초래하는 간접적인 효과 (예를 들어, 뉴클레오티드 생합성 단백질의 활성 조절은 이 박테리아로부터의 유기산 또는 지방산 생산에 영향을 미치는 데, 이는 필요한 보조인자, 에너지 화합물 또는 전구체 분자의 공급 증가 또는 성장 개선에 기인한 것일 수 있다)를 발휘할 수 있다. 본 발명의 측면은 아래에 더욱 자세히 기재되어 있다.
I. 정밀 화학물질
용어 "정밀 화학물질"은 당업계에 잘 인지되어 있고, 제약, 농업 및 화장품 산업과 같은, 그러나 이에 제한되지 않는 다양한 산업에 이용되는 생물에 의해 생산되는 분자를 포함한다. 이러한 화합물로는 타르타르산, 이타콘산 및 디아미노피멜산과 같은 유기산, 단백질생성 및 비-단백질생성 아미노산, 퓨린 및 피리미딘 염기, 뉴클레오시드, 및 뉴클레오티드 (예를 들어, 문헌 [Kuninaka, A. (1996) Nucleotides and related compounds, p.561-612, in Biotechnology vol. 6, Rehm et al., eds. VCH: Weinheim]에 기재되어 있고 이들의 내용은 본 명세서에 포함되는 것으로 함), 지질, 포화 및 불포화 지방산 (예를 들어, 아라키돈산), 디올 (예를 들어, 프로판디올 및 부탄디올), 탄수화물 (예를 들어, 히알루론산 및 트레할로스), 방향족 화합물 (예를 들어,방향족 아민, 바닐린 및 인디고), 비타민 및 보조인자 (문헌 [Ullmann's Encyclopedia of Industrial Chemistry, vol. A27, "Vitamins", p.443-613 (1996) VCH: Weinheim 및 그 안의 참고문헌], 및 문헌 [Ong, A.S., Niki, E. & Packer, L. (1995) "Nutrition, Lipids, Health, and Disease" Proceedings of the UNESCO/Confederation of Scientific and Technological Associations in Malaysia, and the Society for Free Radical Research Asia, held Sept. 1-3,1994 at Penang, Malaysia, AOCS Press, (1995)]에 기재되어 있음), 효소, 폴리펩티드 [Cane et al. (1998) Science 282: 63-68], 및 문헌 [Gutcho (1983) Chemicals by Fermentation, Noyes Data Corporation, ISBN: 0818805086] 및 그 내의 참고문헌에 기재된 다른 모든 화학물질이 있다. 이들 정밀 화학물질 중 일부의 대사 및 용도는 아래에 더욱 자세히 기재될 것이다.
A. 아미노산 대사 및 용도
아미노산은 모든 단백질의 기본 구조 단위를 구성하므로 모든 생물에서 정상적인 세포 기능에 필수적이다. 용어 "아미노산"은 당업계에 인지되어 있다. 아미노산 중 단백질생성 아미노산은 20종이며 펩티드 결합으로 연결되어 있는 단백질의 구조 단위로 작용하는 반면, 비-단백질생성 아미노산 (수백 종이 공지되어 있음)은 정상적으로는 단백질에서 발견되지 않는다 (문헌 [Ulmann's Encyclopedia of Industrial Chemistry, vol. A2, p.57-97 VCH: Weinheim (1985)] 참조). L-아미노산이 통상적으로 자연 발생 단백질에서 발견되는 유일한 형태이지만, 아미노산은 D-광학 또는 L-광학 구조일 수 있다. 20종의 단백질생성 아미노산 각각의 생합성 및 분해 경로의 특징은 원핵세포 및 진핵세포 둘다에서 잘 규명되어 있다 (예를 들어, 문헌 [Stryer, L. Biochemistry, 3rd edition, pages 578-590 (1988)] 참조). 생합성의 복잡성으로 인한 일반적인 영양 요구물이기 때문에 "필수" 아미노산이라고 지칭되는 아미노산 (히스티딘, 이소루이신, 루이신, 리신, 메티오닌, 페닐알라닌, 트레오닌, 트립토판 및 발린)은 단순한 생합성 경로에 의해 나머지 11종의 "비필수" 아미노산 (알라닌, 아르기닌, 아스파라진, 아스파르테이트, 시스테인, 글루타메이트, 글루타민, 글리신, 프롤린, 세린 및 티로신)으로 쉽게 전환된다. 고등동물은 필수 아미노산 중 일부를 합성하는 능력을 보유하지만, 상기 필수 아미노산 은 식사로부터 공급되어야 정상적인 단백질 합성이 일어난다.
아미노산의 단백질 생합성에서의 기능 이외에도, 이들 아미노산은 그 자체가 흥미로운 화학물질이고, 다수의 아미노산이 식품, 사료, 화학물질, 화장품, 농업 및 제약 산업에 다양하게 사용될 수 있는 것으로 밝혀져 있다. 리신은 인간 뿐만 아니라 가금 및 돼지와 같은 단위 (monogastric) 동물의 영양에 있어서도 중요한 아미노산이다. 글루타메이트는 향미제 첨가물 (모노-소듐 글루타메이트, MSG)로서 가장 흔히 사용되고, 아스파르테이트, 페닐알라닌, 글리신 및 시트테인도 식품 산업 전반에 걸쳐 광범위하게 사용된다. 글리신, L-메티오닌 및 트립토판은 모두 제약 산업에 사용된다. 글루타민, 발린, 루이신, 이소루이신, 히스티딘, 아르기닌, 프롤린, 세린 및 알라닌은 제약 및 화장품 산업 둘다에 사용된다. 트레오닌, 트립토판 및 D/L-메티오닌은 통상적인 사료 첨가제이다 (문헌 [Leuchtenberger, W. (1996) Amino acids technical production and use, p.466-502 in Rehm et al. (eds.) Biotechnology vol. 6, chapter 14a, VCH: Weinheim]). 또한, 이들 아미노산은 합성 아미노산 및 단백질, 예를 들어, N-아세틸시스테인, S-카르복시메틸-L-시스테인, (S)-5-히드록시트립토판, 및 문헌 [Ulmann's Encyclopedia of Industrial Chemistry, vol. A2, p.57-97, VCH: Weinheim, 1985]에 기재된 다른 것의 합성을 위한 전구체로 유용하다는 것이 밝혀져 있다.
박테리아 등과 같이 이들 천연 아미노산을 생산할 수 있는 생물에서의 이들 천연 아미노산의 생합성 특징은 잘 규명되어 있다 (박테리아 아미노산 생합성 및 그의 조절에 대한 자세한 것은 문헌 [Umbarger, H.E. (1978) Ann. Rev. Biochem. 47: 533-606] 참조). 글루타메이트는 시트르산 사이클의 중간체인 α-케토글루타레이트의 환원성 아미노화에 의해 합성된다. 글루타민, 프롤린 및 아르기닌은 각각 글루타메이트로부터 생성된다. 세린의 생합성은 3-포스포글리세레이트 (해당작용의 중간체)로 출발하여, 산화, 트랜스아미노화 및 가수분해의 3 단계 과정 후에 세린이 생성된다. 시스테인 및 글리신은 둘다 세린으로부터 생성되는데, 시스테인은 호모시스테인과 세린의 축합에 의해 생성되며, 글리신은 세린 트랜스히드록시메틸라제에 의해 촉매되는 반응에서 측쇄 β-탄소 원자가 테트라히드로폴레이트로 전달되어 생성된다. 페닐알라닌 및 티로신은 프레페네이트의 합성 후 최종 두 단계에서만 다른 9 단계 생합성 경로에서 해당작용 및 펜토스 포스페이트 경로 전구체인 에리쓰로스 4-포스페이트 및 포스포에놀피루베이트로부터 합성된다. 트립토판도 이들 두 초기 분자로부터 합성되지만, 그의 합성은 11 단계 경로이다. 티로신은 페닐알라닌 히드록실라제에 의해 촉매되는 반응에서 페닐알라닌으로부터 합성될 수도 있다. 알라닌, 발린 및 루이신은 해당작용의 최종 생성물인 피루베이트의 모든 생합성 생성물이다. 아스파르테이트는 시트르산 사이클의 중간체인 옥살로아세테이트로부터 형성된다. 아스파라진, 메티오닌, 트레오닌 및 리신 각각은 아스파르테이트의 전환에 의해 생성된다. 이소루이신은 트레오닌으로부터 형성된다. 복잡한 9 단계 경로에서 활성화된 당인 5-포스포리보실-1-피로포스페이트로부터 히스티딘이 생성된다.
세포의 단백질 합성 필요량을 초과하는 아미노산은 저장될 수 없고, 그 대신에 분해되어 세포의 주요 대사 경로에 대한 중간체로 제공된다 (자세한 것은 문헌 [Stryer, L. Biochemistry 3rd ed. Ch. 21 "Amino Acid Degradation and the Urea Cycle" p.495-516 (1988)] 참조). 세포가 불필요한 아미노산을 유용한 대사 중간체로 전환시킬 수 있다 하더라도, 아미노산 생성은 에너지, 전구체 분자, 및 이들 아미노산을 합성하는 데 필요한 효소를 고려할 때 손실이 큰 합성이다. 따라서, 특정한 아미노산의 존재가 그 자신의 생성을 서서히 또는 완전히 중지시키는 피드백 억제에 의해 아미노산의 생합성이 조절된다는 것은 놀라운 일이 아니다 (아미노산 생합성 경로의 피드백 메카니즘에 대한 전체적인 내용은 문헌 [Stryer, L. Biochemistry 3rd ed. Ch. 24 "Biosynthesis of Amino Acids and Heme" p. 575-600 (1988)] 참조). 따라서, 임의의 특정 아미노산의 생산량은 세포에 존재하는 아미노산의 양에 의해 제한된다.
B. 비타민, 보조인자 및 영양제의 대사 및 용도
비타민, 보조인자 및 영양제는 박테리아와 같은 다른 생물에 의해 쉽게 합성된다 하더라도 고등동물이 합성 능력을 상실하여 섭취해야 하는 분자의 다른 군을 구성한다. 이들 분자는 그 자체가 생활성 물질이거나, 다양한 대사 경로에서 전자 전달자 또는 중간체로 작용할 수 있는 생물학적 활성 물질의 전구체이다. 이들 화합물은 그 영양적 가치 뿐 아니라, 색소, 항산화제 및 촉매로서, 또는 다른 과정의 보조제로서도 상당한 산업적 가치를 갖는다 (이들 화합물의 구조, 활성 및 산업적인 용도에 대한 것은 예를 들어, 문헌 [Ullman's Encyclopedia of Industrial Chemistry, "Vitamins" vol. A27, p.443-613, VCH: Weinheim, 1996] 참조). 용어 "비타민"은 당업계에 인지되어 있고, 생물의 정상적인 기능을 위해서는 필요하지만 생물이 스스로 합성할 수 없는 영양분을 포함한다. 비타민 군은 보조인자 및 영양제 화합물도 포함할 수 있다. 용어 "보조인자"는 정상적인 효소 활성이 일어나는 데 필요한 비-단백질생성 화합물을 포함한다. 이러한 화합물은 유기성 또는 무기성일 수 있고, 본 발명의 보조인자 분자는 유기성인 것이 바람직하다. 용어 "영양제 (nutraceutical)"는 식물 및 동물, 특히 인간에게 건강상 유익한 식이성 보충물을 포함한다. 이러한 분자의 예로는 비타민, 항산화제 및 일부 지질 (예를 들어, 다불포화 지방산)이 있다.
이들을 생산할 수 있는 생물, 예를 들어, 박테리아에서 일어나는 이들 분자의 생합성의 특징은 잘 규명되어 있다 (문헌 [Ullman's Encyclopedia of Industrial Chemistry, "Vitamins" vol. A27, p.443-613, VCH: Weinheim, 1996], 문헌 [Michal, G. (1999) Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology, John Wiley & Sons], 문헌 [Ong, A.S., Niki, E. & Packer, L. (1995) "Nutrition, Lipids, Health, and Disease "Proceedings of the UNESCO/Confederation of Scientific and Technological Associations in Malaysia, and the Society for Free Radical Research-Asia, held Sept. 1-3, 1994 at Penang, Malaysia, AOCS Press: Champaign, IL X, 374 S]).
티아민 (비타민 B1)은 피리미딘과 티아졸 잔기의 화학적 커플링에 의해 생성된다. 리보플라빈 (비타민 B2)는 구아노신-5'-트리포스페이트 (GTP) 및 리보스-5'-포스페이트로부터 합성된다. 그 다음, 상기 리보플라빈은 플라빈 모노뉴클레오티 드 (FMN) 및 플라빈 아데닌 디뉴클레오티드 (FAD)의 합성에 사용된다. 총칭하여 "비타민 B6"로 지칭되는 화합물 족 (예를 들어, 피리독신, 피리독사민, 피리독사-5'-포스페이트 및 시판되는 피리독신 히드로클로라이드)은 모두 통상적인 구조 단위인 5-히드록시-6-메틸피리딘의 유도체이다. 판토테네이트 (판토텐산, (R)-(+)-N-(2,4-디히드록시-3,3-디메틸-1-옥소부틸)-β-알라닌)은 화학적인 합성 또는 발효에 의해 생성될 수 있다. 판토테네이트의 생합성의 최종 단계는 β-알라닌과 판토산의 ATP-유도 축합으로 구성된다. 판토산으로 전환하는 생합성 단계, β-알라닌으로 전환하는 생합성 단계 및 판토텐산으로의 축합에 관여하는 효소는 공지되어 있다. 판토테네이트의 대사 활성 형태는 보조효소 A인데, 이 보조효소 A를 위한 생합성은 5 단계 효소 반응으로 진행된다. 판토테네이트, 피리독살-5'-포스페이트, 시스테인 및 ATP는 보조효소 A의 전구체이다. 이들 효소는 판토테네이트의 형성을 촉매할 뿐만 아니라 (R)-판토산, (R)-판토락톤, (R)-판테놀 (프로비타민 B5), 판테테인 (및 그의 유도체) 및 보조효소 A의 생성도 촉매한다.
미생물에서 전구체 분자인 피멜로일-CoA로부터의 비오틴 생합성 과정은 자세히 연구되어 있고 이에 관련된 여러가지 유전자가 확인되어 있다. 상응하는 다수의 단백질이 Fe-클러스터 합성에도 관여하는 것으로 밝혀져 있고 이들 단백질은 nifS 클래스 단백질의 구성원이다. 리포산은 옥타노산으로부터 유도되고, 에너지 대사에서 보조효소로 작용하는데, 상기 리포산은 에너지 대사에서 피루베이트 디히드로게나제 (dehydrogenase) 결합체 및 α-케토글루타레이트 디히드로게나제 결합 체의 일부가 된다. 폴레이트는 모두 엽산의 유도체 물질의 군이고, 엽산은 L-글루탐산, p-아미노-벤조산 및 6-메틸프테린으로부터 유도된다. 대사 중간체인 구아노신-5'-트리포스페이트 (GTP), L-글루탐산 및 p-아미노-벤조산으로부터 출발하는, 엽산 및 그의 유도체의 생합성은 일부 미생물에서 상세히 연구되어 있다.
코리노이드 (예를 들어, 코발라민 및 특히 비타민 B12) 및 포피린은 테트라피롤 고리계에 의해 특징지워지는 화학물질의 군에 속한다. 비타민 B12의 생합성은 그 특징이 완전히 규명되어 있지는 않지만 다수의 효소 및 기질이 현재 공지되어 있다는 점에서 충분히 복잡하다. 니코틴산 (니코티네이트) 및 니코틴아미드는 "니아신"으로도 지칭되는 피리딘 유도체이다. 니아신은 중요한 보조효소인 NAD (니코틴아미드 아데닌 디뉴클레오티드), NADP (니코틴아미드 아데닌 디뉴클레오티드 포스페이트) 및 그들의 환원형의 전구체이다.
이들 화합물의 대량 생산은 비록 이들 화학물질 중 일부, 예를 들어, 리보플라빈, 비타민 B6, 판토테네이트 및 비오틴이 미생물의 대량 배양에 의해서도 생산된다 하더라도 세포-유리 화학 합성에 주로 의존한다. 비타민 B12만이 발효에 의해 전적으로 생성되는데, 이는 비타민 B12의 합성의 복잡성 때문이다. 시험관내 방법론은 재료 및 시간, 종종 많은 비용의 상당한 투입을 요구한다.
C. 퓨린, 피리미딘, 뉴클레오시드 및 뉴클레오티드의 대사 및 용도
퓨린 및 피리미딘 대사 유전자 및 이들의 상응하는 단백질은 종양 질환 및 바이러스 감염의 치료에 중요한 표적이다. 용어 "퓨린" 또는 "피리미딘"은 핵산, 보조효소 및 뉴클레오티드의 구성 성분인 질소 함유 염기를 포함한다. 용어 "뉴클레오티드"는 질소 함유 염기, 오탄당 (RNA의 경우, 상기 당은 리보스이고, DNA의 경우, 상기 당은 D-데옥시리보스임) 및 인산으로 구성된, 핵산 분자의 기본 구조 단위를 포함한다. 용어 "뉴클레오시드"는 뉴클레오티드의 전구체로 작용하지만 뉴클레오티드가 갖는 인산 잔기가 없는 분자를 포함한다. 이들 분자의 생합성을 억제하거나 핵산 분자를 형성하기 위한 이들 분자의 동원(動員)을 억제함으로써, RNA 및 DNA 합성 억제가 가능하고, 암세포에 표적화시키는 방식으로 상기 활성을 억제하여 종양 세포의 분열 및 복제 능력을 억제할 수 있다. 또한, 핵산 분자를 형성하기 보다는 에너지 저장물 (즉, AMP) 또는 보조효소 (즉, FAD 및 NAD)로 작용하는 뉴클레오티드도 있다.
이들 화학물질이 퓨린 및(또는) 피리미딘 대사에 영향을 줌으로써 상기 의학적 증상에 사용될 수 있다는 것은 여러 가지 문헌에 기재되어 있다 (예를 들어, 문헌 [Christopherson, R.I. and Lyons, S.D. (1990) "Potent inhibitors of de novo pyrimidine and purine biosynthesis as chemotherapeutic agents." Med. Res. Reviews 10: 505-548]). 퓨린 및 피리미딘 대사에 관여하는 효소의 연구는 예를 들어, 면역억제제 또는 항증식제로 사용할 수 있는 신약의 개발에 초점을 두고 있다 (문헌 [Smith, J.L., (1995)"Enzymes in nucleotide synthesis." Curr. Opin. Struct. Biol. 5: 752-757, (1995) Biochem Soc. Transact. 23: 877-902]). 그러나, 퓨린 및 피리미딘 염기, 뉴클레오시드 및 뉴클레오티드는 여러 가지 정밀 화학 물질 (예를 들어, 티아민, S-아데노실-메티오닌, 폴레이트 또는 리보플라빈)의 생합성에 있어서 중간체로서의 용도, 세포를 위한 에너지 전달자 (예를 들어, ATP 또는 GTP)로서의 용도, 및 통상적으로 향 상승제 (예를 들어, IMP 또는 GMP)로 사용되는 화학물질 자체를 위한 용도 또는 여러 가지 의학 용도를 갖는다 (예를 들어, 문헌 [Kuninaka, A. (1996) Nucleotides and Related Compounds in Biotechnology vol. 6, Rehm et al., eds. VCH: Weinheim, p.561612] 참조). 또한, 퓨린, 피리미딘, 뉴클레오시드 또는 뉴클레오티드 대사에 관여하는 효소를 표적으로 사용하여 살진균제, 제초제 및 살충제를 비롯한, 농작물 보호용 화학물질을 개발하는 연구가 증가하고 있다.
박테리아에서 이들 화합물 대사의 특징은 규명되어 있다 (자세한 내용은 예를 들어, 문헌 [Zalkin, H. and Dixon, J. E. (1992) "de novo purine nucleotide biosynthesis", in: Progress in Nucleic Acid Research and Molecular Biology, vol. 42, Academic Press:, p.259-287], 및 문헌 [Michal, G. (1999) "Nucleotides and Nucleosides", Chapter 8 in: Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology, Wiley: New York] 참조). 퓨린의 대사는 집중적인 연구의 대상이고, 세포의 정상적인 기능에 필수적이다. 고등 동물의 손상된 퓨린 대사는 통풍과 같은 심각한 질환을 초래할 수 있다. 퓨린 뉴클레오티드는 구아노신-5'-모노포스페이트 (GMP) 또는 아데노신-5'-모노포스페이트 (AMP)를 생성시키는 중간체 화합물인 이노신-5'-포스페이트 (IMP)를 통해 일련의 단계에서 리보스-5-포스페이트로부터 합성되고, 이들 GMP 또는 AMP로부터 뉴클레오티드로 사용되 는 트리포스페이트가 용이하게 형성된다. 이들 화합물은 에너지 저장물로도 사용되므로, 이들의 분해는 세포에서 다수의 다양한 생합성 과정을 위한 에너지를 공급한다. 피리미딘 생합성은 리보스-5-포스페이트로부터의 유리딘-5'-모노포스페이트 (UMP)의 형성에 의해 진행된다. 그 다음, UMP가 시티딘-5'-트리포스페이트 (CTP)로 전환된다. 이들 모든 뉴클레오티드의 디옥시 형태는 뉴클레오티드의 디포스페이트 리보스 형태가 뉴클레오티드의 디포스페이트 데옥시리보스 형태로 전환되는 1 단계 환원 반응에서 생성된다. 인산화시, 이들 분자는 DNA 합성에 참여할 수 있다.
D. 트레할로스의 대사 및 용도
트레할로스는 α,α-1,1 결합에 의해 결합된 두 가지 당 분자로 구성된다. 트레할로스는 감미료, 건조 또는 동결 식품용 첨가제로서 식품 산업, 및 음료 산업에 통상적으로 사용된다. 그러나, 제약, 화장품 및 생물공학 산업에도 사용된다 (예를 들어, 문헌 [Nishimoto et al., (1998) 미국 특허 제5,759,610호], 문헌 [Singer, M.A. and Lindquist, S. (1998) Trends Biotech. 16: 460467], 문헌 [Paiva, C.L.A. and Panek, A.D. (1996) Biotech. Ann. Rev. 2: 293-314], 문헌 [Shiosaka, M. (1997) J. Japan 172: 97-10] 참조). 트레할로스는 다수의 미생물로부터 효소에 의해 생성되고 주변 배지내로 자연적으로 방출되는데, 트레할로스는 당업계에 공지된 방법을 이용하여 상기 배지로부터 수득할 수 있다.
II. 본 발명의 요소 및 방법
본 발명은, 적어도 부분적으로는, 하나 이상의 세포내 대사 경로에서 기능하 거나 역할을 발휘하는, 본원에서 MP 핵산 및 MP 단백질 분자로 언급되는 새로운 분자의 발견을 기초로 한다. 한 실시양태에서, MP 분자는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 하나 이상에 관여하는 효소 반응을 촉매한다. 바람직한 실시양태에서, 코리네박테리움 글루타미쿰의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 하나 이상에서 본 발명의 MP 분자의 활성은 이 생물에 의한 원하는 정밀 화학물질의 생산에 영향을 준다. 특히 바람직한 실시양태에서, 본 발명의 MP 단백질이 관여하는 코리네박테리움 글루타미쿰 대사 경로가 생산성 또는 효율 면에서 조절되도록 본 발명의 MP 분자의 활성을 조절하여, 코리네박테리움 글루타미쿰에 의한 원하는 정밀 화학물질의 생산 효율 또는 생산성을 직접적 또는 간접적으로 조절한다.
용어 "MP 단백질" 또는 "MP 폴리펩티드"에는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 하나 이상에서의 효소 반응을 촉매하는 등의 역할을 하는 단백질이 포함된다. MP 단백질의 예에는 표 1에 기재된 MP 유전자 및 홀수 서열 번호의 서열에 의해 코딩되는 것들이 포함된다. 용어 "MP 유전자" 또는 "MP 핵산 서열"에는 코딩 영역 및 이에 상응하는 비번역 5' 및 3' 서열 영역으로 구성된, MP 단백질을 코딩하는 핵산 서열이 포함된다. MP 유전자의 예로는 표 1에 기재된 것들이 포함된다. 용어 "생산" 또는 "생산성"은 당업계에서 인식되는 용어이며, 소정의 시간 및 소정의 발효 용적내에서 형성되는 발효 생성물의 농도 (예를 들어, 1시간에 1리터 당 kg 생성물)가 포함된 다. 용어 "생산 효율"에는 특정 생성물 농도를 달성하는데 요구되는 시간 (예를 들어, 세포가 특정 비율의 정밀 화학물질 생성물을 얻는데 걸리는 시간)이 포함된다. 용어 "수율" 또는 "생성물/탄소 수율"은 당업계에서 인식되는 용어이며, 탄소 공급원의 생성물(즉, 정밀 화학물질)로의 전환 효율이 포함된다. 이 용어는 일반적으로는, 예를 들어, 탄소 공급원 kg 당 생성물 kg으로 표기된다. 화합물의 수율 또는 생산율을 증대시킴으로써, 소정의 시간 동안 얻어지는 수득량의 배양물 중 이 화합물의 회수된 분자의 양 또는 유용한 분자의 양은 증가하게 된다. 용어 "생합성" 또는 "생합성 경로"는 당업계에서 인식되는 용어이고, 세포에 의한 중간체 화합물로부터의 화합물, 바람직하게는 유기 화합물의 합성을 포함하며, 다단계의 고도로 조절되는 과정일 수 있다. 용어 "분해" 또는 "분해 경로"는 당업계에서 인식되는 용어이고, 세포에 의한 화합물, 바람직하게는 유기 화합물의 분해 생성물 (일반적으로 말해서, 더 작거나 덜 복잡한 구조의 분자)로의 분해를 포함하며, 다단계의 고도로 조절되는 과정일 수 있다. 이어서, 특정 화합물의 대사 (예를 들어, 글리신 등의 아미노산의 대사)에는 이러한 화합물과 관련되는 세포의 전체 생합성, 변형, 및 분해 경로가 포함된다.
다른 실시양태에서, 본 발명의 MP 분자는 코리네박테리움 글루타미쿰과 같은 미생물에서 정밀 화학물질 등의 원하는 분자의 생산을 조절할 수 있다. 재조합 유전 기술을 이용하여, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스에 관한 본 발명의 생합성 또는 분해 효소 1종 이상을 조작하여, 그 기능을 조절할 수 있다. 예를 들면, 생합성 효소의 효율을 개선시키거 나, 이 효소의 알로스테릭 제어 영역을 파괴하여 화합물 생산의 피드백 억제가 저해되도록 할 수 있다. 유사하게, 치환, 결실, 또는 부가에 의해 분해 효소를 결실시키거나 변형시켜, 세포의 생존력을 손상시키지 않고 원하는 화합물에 대한 이의 분해 활성이 감소되게 할 수 있다. 각 경우에서, 원하는 정밀 화학물질 생산에 관한 전반적인 생산 속도 또는 수율이 증가될 수 있다.
또한, 본 발명의 단백질 및 핵산 분자에서의 이러한 변경은 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 뿐 아니라, 다른 정밀 화학물질의 생산도 개선시킬 수 있다. 임의의 화합물 대사는 세포내 다른 생합성 및 분해 경로와 반드시 얽혀있고, 한 경로에 필요한 보조인자, 중간체 또는 기질은 이러한 다른 경로에 의해 공급되거나 제한되는 것으로 보인다. 그러므로, 본 발명의 단백질 1종 이상의 활성을 조절하여, 다른 정밀 화학적 생합성 또는 분해 경로의 활성 효율 또는 생산성에 영향을 줄 수 있다. 예를 들어, 아미노산은 모든 단백질의 구조 단위로 기능하지만, 세포내에서는 단백질 합성을 제한하는 수준으로 존재한다; 그러므로, 세포내에서 아미노산 1종 이상의 생산 효율 또는 수율을 증가시켜, 생합성 단백질 또는 분해 단백질 등의 단백질이 더욱 쉽게 합성되도록 할 수 있다. 유사하게, 대사 경로 효소의 변경으로 특정 부반응이 더욱 또는 덜 일어나게 되어, 원하는 정밀 화학물질의 생성에 중간체 또는 기질로 이용되는 화합물 1종 이상의 과잉생산 또는 생산부족을 초래할 수 있다.
본 발명의 단리된 핵산 서열은 명칭이 ATCC13032로 부여된, 아메리칸 타입 컬쳐 콜렉션에서 분양받을 수 있는 코리네박테리움 글루타미쿰 균주의 게놈내에 포 함되어 있다. 단리된 코리네박테리움 글루타미쿰 MP DNA의 뉴클레오티드 서열 및 코리네박테리움 글루타미쿰 MP 단백질의 예상 아미노산 서열은 각각 서열목록에서 홀수 서열 번호 및 짝수 서열 번호로 나타내었다. 이러한 뉴클레오티드 서열을, 대사 경로 단백질을 코딩하는 서열로서 분류 및(또는) 확인하는 컴퓨터 분석을 수행하였다.
본 발명은 또한 본 발명의 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호의 서열)과 실질적으로 상동성인 아미노산 서열을 갖는 단백질에 관한 것이다. 본원에 사용된 바와 같이, 선택되는 아미노산 서열과 실질적으로 상동성인 아미노산 서열을 갖는 단백질은 선택되는 아미노산, 예를 들어, 선택되는 전체 아미노산 서열에 대해 약 50% 이상의 상동성이 있다. 선택되는 아미노산 서열과 실질적으로 상동성인 아미노산 서열을 갖는 단백질은 선택되는 아미노산 서열에 대해 약 50 내지 60% 이상, 바람직하게는 약 60 내지 70% 이상, 더욱 바람직하게는 약 70 내지 80%, 80 내지 90%, 또는 90 내지 95% 이상, 가장 바람직하게는 약 96% 이상, 97% 이상, 98% 이상, 99% 이상의 상동성이 있다.
본 발명의 MP 단백질 또는 생물학적으로 활성인 그의 일부 또는 단편은 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 하나 이상의 효소 반응을 촉매하거나, 표 1에 기재된 활성 중 하나 이상을 가질 수 있다.
본 발명의 다양한 측면은 하기 서브섹션에 보다 상세히 기재되어 있다.
A. 단리된 핵산 분자
본 발명의 한 측면은 MP 폴리펩티드 또는 생물학적으로 활성인 그의 일부를 코딩하는 단리된 핵산 분자뿐 아니라 MP-코딩 핵산 (예를 들어, MP DNA) 확인 또는 증폭을 위한 혼성화 프로브 또는 프라이머로 사용하기에 충분한 핵산 단편에 관한 것이다. 본원에 사용된 바와 같이, 용어 "핵산 분자"는 DNA 분자 (예를 들어, cDNA 또는 게놈 DNA), RNA 분자 (예를 들어, mRNA), 및 뉴클레오티드 유사체를 사용하여 생성되는 DNA 또는 RNA 유사체를 포함하는 의미이다. 이 용어에는 또한 유전자의 코딩 영역의 3' 및 5' 말단의 둘 다에 위치하는 비번역 서열, 코딩 영역의 5' 말단으로부터 상류의 약 100개 이상의 뉴클레오티드 서열, 및 이 유전자의 코딩 영역의 3' 말단으로부터 하류의 약 20개 이상의 뉴클레오티드 서열이 포함된다. 핵산 분자는 단일 가닥 또는 이중 가닥일 수 있으며, 바람직하게는 이중 가닥 DNA이다. "단리된" 핵산 분자는 핵산의 천연 공급원에 존재하는 다른 핵산 분자로부터 분리되는 것이다. 바람직하게는, "단리된" 핵산은 이 핵산이 유도되는 생물의 게놈 DNA에서 본래 핵산의 양측면에 있는 서열 (즉, 핵산의 5' 및 3' 말단에 위치하는 서열)을 가지고 있지 않다. 예를 들어, 다양한 실시양태에서, 단리된 MP 핵산 분자는 이 핵산이 유도되는 세포 (예를 들어, 코리네박테리움 글루타미쿰 세포)의 게놈 DNA에서 본래 핵산 분자의 양측면에 있는 약 5 kb, 4 kb, 3 kb, 2 kb, 1 kb, 0.5 kb 또는 0.1 kb 보다 작은 크기의 뉴클레오티드 서열을 포함할 수 있다. 또한, "단리된" 핵산 분자, 예를 들어, DNA 분자는, 재조합 기술에 의해 생산되는 경우 다른 세포 물질 또는 배양 배지, 또는 화학적으로 합성되는 경우 화학물질 전구체 또는 다른 화학물질을 실질적으로 함유하지 않는다.
표준 분자 생물학 기술 및 본원에 제공되는 서열 정보를 이용하여, 본 발명의 핵산 분자, 예를 들어, 서열목록에서 홀수 서열 번호의 뉴클레오티드 서열을 갖는 핵산 분자 또는 그의 일부를 단리할 수 있다. 예를 들어, 서열목록에서 홀수 서열 번호의 서열 중 하나의 전부 또는 일부를 혼성화 프로브로 사용하고 표준 혼성화 기술 (예를 들어, 문헌 [Sambrook, J., Fritsh, E.F., and Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd, ed., Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989]에 기재된 바와 같은 혼성화 기술)을 사용하여 코리네박테리움 글루타미쿰 라이브러리로부터 코리네박테리움 글루타미쿰 MP DNA를 단리할 수 있다. 더우기, 본 발명의 핵산 서열 (예를 들어, 이와 동일한 서열을 기초로 하여 고안된 올리고뉴클레오티드 프라이머를 사용하는 중합효소 연쇄반응에 의해 본 발명의 핵산 서열 (예를 들어, 서열목록에서 홀수 서열 번호의 서열) 중 하나의 전부 또는 일부를 포함하는 핵산 분자를 단리할 수 있음)을 기초로 하여 고안된 올리고뉴클레오티드 프라이머를 사용하는 중합효소 연쇄반응에 의해 본 발명의 핵산 서열 (예를 들어, 홀수 서열 번호의 서열) 중 하나의 전부 또는 일부를 포함하는 핵산 분자를 단리할 수 있다. 예를 들어, mRNA는 정상 내피세포로부터 (예를 들어, 문헌 [Chirgwin et al. (1979) Biochemistry 18:5294-5299]의 구아니디늄-티오시아네이트 추출 방법에 의해) 단리할 수 있고, DNA는 역전사효소 (예를 들어, 미국 메릴랜드주 베테스다 소재의 Gibco/BRL로부터 입수가능한 몰로네이 (Moloney) MLV 역전사효소, 또는 미국 플로리다주 페터스부르크 스트리트에 소재한 세이까가꾸 아메리카, 인크. (Seikagaku America, Inc.)로부터 입수가능한 AMV 역전사효소)를 사용하여 제조할 수 있다. 서열목록에 기재된 뉴클레오티드 서열 중 하나를 기초로 하여 중합효소 연쇄반응 증폭을 위한 합성 올리고뉴클레오티드 프라이머를 고안할 수 있다. 본 발명의 핵산은 cDNA 또는, 별법으로, 게놈 DNA를 주형으로 사용하고 표준 PCR 증폭 기술에 따라 적절한 올리고뉴클레오티드 프라이머를 사용하여 증폭시킬 수 있다. 이와 같이 증폭된 핵산을 적절한 벡터내에 클로닝하고 DNA 서열 분석에 의해 특성화할 수 있다. 또한, MP 뉴클레오티드 서열에 상응하는 올리고뉴클레오티드는 표준 합성 기술, 예를 들어, 자동 DNA 합성기를 사용하여 제조할 수 있다.
바람직한 실시양태에서, 본 발명의 단리된 핵산 분자는 서열목록에 기재된 뉴클레오티드 서열 중 하나를 포함한다. 서열목록에 기재된 바와 같은 본 발명의 핵산 서열은 본 발명의 코리네박테리움 글루타미쿰 MP DNA에 상응한다. 이 DNA는 MP 단백질을 코딩하는 서열 (즉, 서열목록에서 홀수 서열 번호의 서열에 나타낸 "코딩 영역")뿐 아니라 서열목록에서 각 홀수 서열 번호의 서열에 나타낸 5' 비번역 서열 및 3' 비번역 서열도 포함한다. 또는, 핵산 분자는 서열목록의 핵산 서열 중 하나의 코딩 영역만을 포함할 수 있다.
본 출원의 목적을 위해, 서열목록에 기재된 핵산 및 아미노산 서열 각각을 "RXA", "RXN", "RXS" 또는 "RXC" 뒤에 5개의 숫자가 있는, 확인용 RXA, RXN, RXS 또는 RXC 수 (즉, RXA00007, RXN00023, RXS00116 또는 RXC00128)로 표시한 것을 알 것이다. 핵산 서열 각각은 세 부분, 즉 5' 상류 영역, 코딩 영역 및 하류 영역으로 구성되어 있다. 이들 세 영역 각각에는 동일한 RXA, RXN, RXS 또는 RXC 표시로 확인시켜 혼란을 방지했다. 이외에, "서열목록에서 홀수 서열 번호 중 하나"란, 서열목록의 핵산 서열 중 임의의 것을 말하며, 이들은 RXA, RXN, RXS 또는 RXC 표시가 달라 구별될 수도 있다. 이 서열 각각의 코딩 영역은 또한 서열목록에서 짝수 서열 번호로 기재되어 있는 상응 아미노산 (상응 핵산 서열 바로 다음에 기재되어 있음)으로 번역된다. 예를 들어, RXA02229에 대한 코딩 영역은 서열 1에 기재되어 있으며, 그가 코딩하는 아미노산 서열은 서열 2에 기재되어 있다. 본 발명의 핵산 분자의 서열은, 이들이 쉽게 상호관련될 수 있도록, 이들이 코딩하는 아미노산 분자로서 동일한 RXA, RXN, RXS 또는 RXC 표시에 의해 확인된다. 예를 들어, RXA02229, RX00351, RXS02970 및 RXC02390으로 표시된 아미노산 서열은 각각 핵산 분자 RXA02229, RX00351, RXS02970 및 RXC02390의 뉴클레오티드 서열의 코딩 영역의 번역물이다. 본 발명의 RXA, RXN, RXS 및 RXC 뉴클레오티드 및 아미노산 서열과 이들의 배정된 서열 번호 사이의 상응 관계는 표 1에 기재되어 있다.
본 발명의 유전자들 중 몇몇은 "F-표시 유전자"이다. F-표시 유전자는 표 1에 기재된 유전자들을 포함하며, 이들은 RXA, RXN, RXS 또는 RXC 표시 앞에 'F'를 갖는다. 예를 들어, 표 1에 나타낸 바와 같이, "F RXA01009"로 표시된 서열 5는 F-표시 유전자이며, 서열 73, 75 및 77 (표 1에서 각각 "F RXA00007", "F RXA00364" 및 "F RXA00367"로 표시됨)도 마찬가지이다.
한 실시양태에서, 본 발명의 핵산 분자는 표 2에 기재된 것들을 포함하지 않는다. dapD 유전자의 경우, 이 유전자에 대한 서열은 문헌 [Wehrmann, A., et al, (1998) J. Bacteriol. 180(12):3159-3165]에 공개되어 있다. 그러나, 본 발명자들 이 얻은 서열은 공개된 서열 형태 보다 상당히 더 길다. 공개된 서열 형태는 정확하지 않은 개시 코돈에 의존한 것이며, 따라서 실제 코딩 영역의 단편만을 나타낸 것이라고 생각된다.
바람직한 다른 실시양태에서, 본 발명의 단리된 핵산 분자는 본 발명의 뉴클레오티드 서열 (예를 들어, 서열목록에서 홀수 서열 번호의 서열) 중 하나의 상보체인 핵산 분자 또는 그의 일부를 포함한다. 본 발명에 나타낸 뉴클레오티드 서열 중 하나에 대해 상보적인 핵산 분자는 서열목록에 나타낸 뉴클레오티드 서열 (예를 들어, 홀수 서열 번호의 서열) 중 하나에 대해 충분히 상보적인 것이어서, 그는 본 발명의 뉴클레오티드 서열 중 하나와 혼성화함으로써 안정한 이중 나선을 형성한다.
바람직한 다른 실시양태에서, 본 발명의 단리된 핵산 분자는 본 발명의 뉴클레오티드 서열 (예를 들어, 서열목록에서 홀수 서열 번호의 서열 중 한 서열)과 약 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59% 또는 60% 이상, 바람직하게는 약 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 또는 70% 이상, 더욱 바람직하게는 약 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 또는 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 또는 90%, 또는 91%, 92%, 93%, 94% 이상, 더욱 바람직하게는 약 95%, 96%, 97%, 98%, 또는 99% 이상의 상동성이 있는 뉴클레오티드 서열 또는 그의 일부를 포함한다. 상기 언급된 범위에 대해 중간값인 동일성 값 및 범위 (예를 들어, 70 내지 90% 동일 또는 80 내지 95% 동일)는 본 발명에 포함되는 것으로 한다. 예를 들 어, 상기 언급한 임의의 값을 최대값 및(또는) 최소값의 조합으로 사용한 동일성 값의 범위는 본 발명에 포함된다. 추가의 바람직한 실시양태에서, 본 발명의 단리된 핵산 분자는, 예를 들어 엄격 조건하에, 본 발명의 뉴클레오티드 서열 중 하나 또는 그의 일부와 혼성화하는 뉴클레오티드 서열을 포함한다.
또한, 본 발명의 핵산 분자는 서열목록에서 홀수 서열 번호의 서열 중 한 서열의 코딩 영역의 일부만을 포함할 수도 있는데, 예를 들면 프로브 또는 프라이머로 사용될 수 있는 단편 또는 MP 단백질의 생물학적으로 활성인 일부를 코딩하는 단편을 포함할 수 있다. 코리네박테리움 글루타미쿰으로부터의 MP 유전자의 클로닝으로부터 결정되는 뉴클레오티드 서열을 이용하여 다른 유형의 세포 및 생물에서의 MP 상동체 뿐 아니라 다른 코리네박테리아 또는 관련 종으로부터의 MP 상동체 확인 및(또는) 클로닝에 사용하기 위한 프로브 및 프라이머를 고안할 수 있다. 통상적으로, 프로브/프라이머는 실질적으로 정제된 올리고뉴클레오티드를 포함한다. 올리고뉴클레오티드는 통상적으로 엄격 조건하에 본 발명의 뉴클레오티드 서열 (예를 들어, 서열목록에서 홀수 서열 번호의 서열 중 하나) 중 하나의 센스 가닥, 이들 서열들 중 하나의 안티센스 서열, 또는 자연 발생적인 그의 돌연변이체의 약 12개, 바람직하게는 약 25개, 더욱 바람직하게는 약 40, 50 또는 75개 이상의 연속된 뉴클레오티드와 혼성화하는 뉴클레오티드 서열 영역을 포함한다. 본 발명의 뉴클레오티드 서열을 기초로 한 프라이머는 MP 상동체를 클로닝하기 위한 PCR 반응에서 사용될 수 있다. MP 뉴클레오티드 서열을 기초로 한 프로브를 사용하여 동일하거나 상동성인 단백질을 코딩하는 전사체 또는 게놈 서열을 찾을 수 있다. 바람직한 실시양태에서, 프로브는 그에 부착되는 표지 기 (label group)를 추가로 포함하며, 예를 들어, 표지 기는 방사성동위원소, 형광성 화합물, 효소 또는 효소 보조인자일 수 있다. 이러한 프로브는, 예를 들어 대상체로부터의 세포 샘플 중 MP-코딩 핵산 수준을 측정함으로써, 예를 들어 MP mRNA 수준을 검출하거나, 게놈 MP 유전자가 변이되었는지 또는 결실되었는지를 결정함으로써, MP 단백질을 잘못 발현시키는 세포를 확인하기 위한 진단용 시험 키트의 일부로 사용될 수 있다.
한 실시양태에서, 본 발명의 핵산 분자는 본 발명의 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호의 서열)과 충분히 상동성이 있는 아미노산 서열을 포함하는 단백질 또는 그의 일부를 코딩하며, 이 단백질 또는 그의 일부는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 효소 반응을 촉매하는 능력을 유지한다. 본원에 사용된 바와 같이, 용어 "충분히 상동성인"이란, 본 발명의 아미노산 서열에 대해 동일 또는 동등한 최소 수의 아미노산 잔기 (예를 들어, 서열목록에서 짝수 서열 번호 중 하나의 서열에 있는 어떤 한 아미노산 잔기와 유사한 측쇄를 갖는 아미노산 잔기)를 포함하는 아미노산 서열을 갖는 단백질 또는 그의 일부를 의미하며, 이 단백질 또는 그의 일부는 코리네박테리움 글루타미쿰의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 효소 반응을 촉매할 수 있다. 이러한 대사 경로의 단백질 구성원은, 본원에 기재된 바와 같이, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 중 하나 이상의 생합성 또는 분해를 촉매하는 기능을 한다. 이러한 활성의 예는 또한 본원에 기재되어 있다. 따라서, "MP 단백질의 기능"은 1종 이상의 상기 대사 경로의 전반적인 기능 발휘에 기여하고, 1종 이상의 정밀 화학물질의 생산 수율, 생산성 및(또는) 생산 효율에 직접 또는 간접적으로 기여한다. MP 단백질 활성의 예는 표 1에 기재되어 있다.
다른 실시양태에서, 단백질은 본 발명의 전체 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호의 서열)과 약 50% 내지 60% 이상, 바람직하게는 약 60% 내지 70% 이상, 더욱 바람직하게는 약 70% 내지 80%, 80% 내지 90%, 90% 내지 95% 이상, 가장 바람직하게는 약 96%, 97%, 98% 또는 99% 이상의 상동성이 있다.
본 발명의 MP 핵산 분자에 의해 코딩되는 단백질의 일부는 바람직하게는 MP 단백질 중 하나의 생물학적으로 활성인 일부이다. 본원에 사용된 바와 같이, 용어 "MP 단백질의 생물학적으로 활성인 일부"는 코리네박테리움 글루타미쿰의 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로 하나 이상의 효소 반응을 촉매하거나, 표 1에 기재된 바와 같은 활성을 갖는 MP 단백질의 일부, 예를 들어, 그의 도메인/모티프를 포함한다. MP 단백질 또는 생물학적으로 활성인 그의 일부가 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 효소 반응을 촉매하는지를 결정하기 위해, 효소 활성 분석법을 수행할 수 있다. 실시예 8에 기재된 바와 같이, 이러한 분석 방법은 당업자에게 공지되어 있다.
MP 단백질의 생물학적으로 활성인 일부를 코딩하는 다른 핵산 단편은 MP 단 백질 또는 펩티드의 코딩 부분을 발현시키는 (예를 들어, 시험관내 재조합 발현시킴으로써) 본 발명의 아미노산 서열 (예를 들어, 서열목록에서 짝수 서열 번호의 서열) 중 하나의 일부를 단리하고, MP 단백질 또는 펩티드의 코딩되는 부분의 활성을 평가함으로써 제조할 수 있다.
본 발명은, 본 발명에 나타낸 뉴클레오티드 서열 (예를 들어, 서열목록에서 홀수 서열 번호의 서열) 중 하나와 상이하지만 유전자 코드의 축퇴성으로 인해 본 발명의 뉴클레오티드 서열에 의해 코딩되는 것과 동일한 MP 단백질을 코딩하는 핵산 분자 (및 그의 일부)를 포함한다. 다른 실시양태에서, 본 발명의 단리된 핵산 분자는 서열목록에 나타낸 아미노산 서열 (예를 들어, 짝수 서열 번호의 서열)을 갖는 단백질을 코딩하는 뉴클레오티드 서열을 갖는다. 다른 실시양태에서, 본 발명의 핵산 분자는 본 발명의 아미노산 서열 (서열목록에서 홀수 서열 번호의 서열에 나타낸 오픈 리딩 프레임에 의해 코딩됨)과 실질적으로 상동성인 전장의 코리네박테리움 글루타미쿰 단백질을 코딩한다.
당업자라면, 한 실시양태에서 본 발명의 서열이 본 발명의 이전에 이용가능했던, 표 2 또는 4에 기재된 젠뱅크 (Genbank) 서열과 같은 선행 기술의 서열을 포함하는 것이 아님을 알 것이다. 한 실시양태에서, 본 발명은 선행 기술의 서열 (예를 들어, 표 2 또는 4에 기재된 젠뱅크 서열 (또는 이러한 서열에 의해 코딩되는 단백질))보다 더 큰 본 발명의 뉴클레오티드 또는 아미노산 서열과 동일성(%)을 갖는 뉴클레오티드 서열 및 아미노산 서열을 포함한다. 예를 들어, 본 발명은 RXA00115 (서열 185)로 표시되는 뉴클레오티드 서열보다 더 크고(거나) 그와 40% 이상의 동일성을 갖는 뉴클레오티드 서열, RXA00131 (서열 991)로 표시되는 뉴클레오티드 서열보다 더 크고(거나) 그와 어느 정도 이상의 동일성이 있는 뉴클레오티드 서열 및 RXA00219 (서열 345)로 표시되는 뉴클레오티드 서열보다 더 크고(거나) 그와 39% 이상의 동일성이 있는 뉴클레오티드 서열이 포함된다. 당업자라면, 주어진 서열에 대한 3개의 최고 히트 각각에 대해 표 4에 나타낸 GAP-계산된 동일성(%) 점수를 조사하고, GAP-계산된 가장 높은 동일성(%)를 100에서 차감하여 본 발명의 임의 주어진 서열에 대한 동일성(%)의 하한 역치를 계산할 수 있을 것이다. 당업자라면 또한 이렇게 계산된 하한 역치보다 더 큰 동일성(%) (예를 들어, 약 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59% 또는 60% 이상, 바람직하게는 약 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 또는 70% 이상, 더욱 바람직하게는 약 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 또는 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 또는 90%, 또는 91%, 92%, 93%, 94% 이상, 더욱 바람직하게는 약 95%, 96%, 97%, 98%, 또는 99% 이상의 동일성)을 갖는 핵산 서열 및 아미노산 서열이 본 발명에 포함됨을 알 것이다.
당업자라면, 서열목록에서 홀수 서열 번호로 기재된 코리네박테리움 글루타미쿰 MP 뉴클레오티드 서열 이외에도, MP 단백질의 아미노산 서열에서의 변화를 초래하는 DNA 서열의 다형성이 집단 (예를 들어, 코리네박테리움 글루타미쿰 집단)내에 존재할 수 있음을 알 것이다. MP 유전자에 있어서의 이러한 유전적 다형성은 이로 인해 집단내의 개체들 사이에 존재할 수 있다. 본원에 사용된 바와 같이, 용 어 "유전자" 및 "재조합 유전자"는 MP 단백질, 바람직하게는 코리네박테리움 글루타미쿰 MP 단백질을 코딩하는 오픈 리딩 프레임을 포함하는 핵산 분자를 지칭한다. 이러한 천연 변이는 통상적으로는 MP 유전자의 뉴클레오티드 서열을 1 내지 5% 변화시킨다. 천연 변이의 결과이며 MP 단백질의 기능적 활성을 변경시키지 않는, 임의 및 모든 이러한 뉴클레오티드 변화 및 그에 따라 나타난 MP에서의 아미노산 다형성은 본 발명의 범위 내에 있는 것으로 한다.
천연 변이체 및 본 발명의 코리네박테리움 글루타미쿰 MP DNA의 비-코리네박테리움 글루타미쿰 상동체에 상응하는 핵산 분자는, 본원에 개시된 코리네박테리움 글루타미쿰 MP 핵산에 대한 이들의 상동성에 기초하여, 엄격 혼성화 조건하에 표준 혼성화 기술에 따라 혼성화 프로브로서 코리네박테리움 글루타미쿰 DNA 또는 그의 일부를 사용하여 단리할 수 있다. 따라서, 다른 실시양태에서, 본 발명의 단리된 핵산 분자의 길이는 뉴클레오티드 15개 이상이며, 엄격 조건하에 서열목록에서 홀수 서열 번호의 뉴클레오티드 서열을 포함하는 핵산 분자와 혼성화한다. 다른 실시양태에서, 핵산의 길이는 뉴클레오티드 30개, 50개, 100개 또는 250개 이상이다. 본원에 사용된 바와 같이, 용어 "엄격 조건하에 혼성화하는"은 서로에 대해 통상적으로 60% 이상 상동성인 뉴클레오티드 서열이 서로와 혼성화된 채로 남아 있는 혼성화 조건 및 세척 조건을 설명하려는 것이다. 바람직하게는, 이 조건은 서로에 대해 통상적으로 약 65% 이상, 더욱 바람직하게는 약 70% 이상, 더욱 바람직하게는 약 75% 이상 상동성인 서열이 서로에 대해 혼성화된 채로 남아 있는 조건이다. 이러한 엄격 조건은 당업자에게 공지되어 있으며, 문헌 [Current Protocols in Molecular Biology, John Wiley & Sons, N.Y. (1989), 6.3.1-6.3.6]에서 찾을 수 있다. 엄격 혼성화 조건의 바람직한 예는 약 45 ℃에서 6 ×염화나트륨/시트르산나트륨 (SSC) 중의 혼성화 및 그 후에 50 내지 65 ℃에서 0.2 ×SSC, 0.1% SDS 중에서의 1회 이상 세척이나, 이에 제한되지 않는다. 바람직하게는, 엄격 조건하에 본 발명의 뉴클레오티드 서열과 혼성화하는 본 발명의 단리된 핵산 분자는 자연 발생적인 핵산 분자에 상응한다. 본원에 사용된 바와 같이, "자연 발생적인" 핵산 분자는 자연에 존재하는 (예를 들어, 천연 단백질을 코딩하는) 뉴클레오티드 서열을 갖는 RNA 또는 DNA 분자를 의미한다. 한 실시양태에서, 핵산은 천연 코리네박테리움 글루타미쿰 MP 단백질을 코딩한다.
또한, 당업자라면 집단내에 존재할 수 있는 MP 서열의 자연 발생적인 변이체 뿐 아니라, 본 발명의 뉴클레오티드 서열 내에 돌연변이에 의한 변화를 도입함으로써, MP 단백질의 기능에의 변경 없이 코딩된 MP 단백질의 아미노산 서열을 변화시킬 수 있음을 알 것이다. 예를 들어, "비필수" 아미노산 잔기에서 아미노산 치환을 일으키는 뉴클레오티드 치환이 본 발명의 뉴클레오티드 서열에서 일어날 수 있다. "비필수 아미노산" 잔기가 상기 MP 단백질의 활성을 변경시키지 않으면서 MP 단백질 (예를 들어, 서열목록에서 짝수 서열 번호의 서열) 중 하나의 야생형 서열로부터 변경될 수 있는 잔기인 반면, "필수" 아미노산 잔기는 MP 단백질 활성에 필요하다. 그러나, 다른 아미노산 잔기 (예를 들어, MP 활성을 갖는 도메인에서 보존되지 않거나, 반보존된 잔기)는 활성에 필수적이지 않을 수도 있어서, MP 활성에의 변경없이 변경될 수 있다.
따라서, 본 발명의 다른 측면은 MP 활성에 필수적이지 않은 아미노산 잔기에서의 변화를 포함하는 MP 단백질을 코딩하는 핵산 분자에 관한 것이다. 이러한 MP 단백질은 서열목록에서 짝수 서열 번호의 서열로부터의 아미노산 서열이 다르며, 본원에 기재된 MP 활성 중 적어도 하나를 보유한다. 한 실시양태에서, 단리된 핵산 분자는, 본 발명의 아미노산 서열과 약 50% 이상 상동성인 아미노산 서열을 포함하며, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 효소 반응을 촉매할 수 있거나, 표 1에 기재된 바와 같은 활성을 1가지 이상 갖는 단백질을 코딩하는 뉴클레오티드 서열을 포함한다. 바람직하게는, 핵산 분자에 의해 코딩되는 단백질은 서열목록에서 홀수 서열 번호의 서열 중 하나의 아미노산 서열에 대해 약 50 내지 60% 이상, 더욱 바람직하게는 이러한 서열 중 하나에 대해 약 60 내지 70% 이상, 더욱 바람직하게는 이러한 서열 중 하나에 대해 약 70 내지 80%, 80 내지 90%, 90 내지 95% 이상, 가장 바람직하게는 본 발명의 아미노산 서열 중 하나에 대해 약 96%, 97%, 98% 또는 99% 이상 상동성이 있다.
2개의 아미노산 서열 (예를 들어, 본 발명의 아미노산 서열 중 하나 및 그의 돌연변이체 형태) 또는 2개의 핵산 서열의 상동성(%)을 결정하기 위해, 최적의 비교 목적에 맞게 서열들을 정렬시킨다 (예를 들어, 다른 단백질 또는 핵산과의 최적의 정렬을 위해 하나의 단백질 또는 핵산의 서열내에 갭을 도입시킬 수 있다). 이어서, 아미노산 위치 또는 뉴클레오티드 위치에 상응하는 아미노산 잔기 또는 뉴클레오티드를 비교한다. 한 서열 (예를 들어, 본 발명의 아미노산 서열 중 하나)내 의 위치가 다른 서열 (예를 들어, 아미노산 서열의 돌연변이체 형태)내의 상응하는 위치와 동일한 아미노산 잔기 또는 뉴클레오티드에 의해 점유되는 경우, 분자는 그 위치에서 상동성이 있는 것이다 (즉, 본원에 사용된 바와 같이, 아미노산 또는 핵산의 "상동성"은 아미노산 또는 핵산의 "동일성"과 동등한 의미이다). 2개 서열 사이의 상동성(%)은 서열들에 의해 공유되는 동일한 위치의 개수의 함수이다 (즉, 상동성(%) = 동일한 위치의 개수/위치의 총 개수 ×100).
코딩되는 단백질내에 하나 이상의 아미노산의 치환, 부가 또는 결실이 도입되도록 본 발명의 뉴클레오티드 서열내에 하나 이상의 뉴클레오티드의 치환, 부가 또는 결실을 도입시킴으로써, 본 발명의 단백질 서열 (예를 들어, 서열목록에서 짝수 서열 번호의 서열)과 상동성인 MP 단백질을 코딩하는 단리된 핵산 분자를 생성시킬 수 있다. 위치 지정 돌연변이유발법 및 PCR-매개 돌연변이유발법과 같은 표준 기술에 의해 본 발명의 뉴클레오티드 서열들 중 하나에 돌연변이를 도입할 수 있다. 바람직하게는, 예상되는 하나 이상의 비필수 아미노산 잔기에서 보존된 아미노산 치환을 수행할 수 있다. "보존된 아미노산 치환"이란 아미노산 잔기가 유사한 측쇄를 갖는 아미노산 잔기로 대체되는 것을 말한다. 유사한 측쇄를 갖는 아미노산 잔기의 군은 당업계에 정의되어 있다. 이러한 군에는 염기성 측쇄를 갖는 아미노산 (예를 들어, 리신, 아르기닌, 히스티딘), 산성 측쇄를 갖는 아미노산 (예를 들어, 아스파라긴산, 글루탐산), 비하전된 극성 측쇄를 갖는 아미노산 (예를 들어, 글리신, 아스파라긴, 글루타민, 세린, 트레오닌, 티로신, 시스테인), 비극성 측쇄를 갖는 아미노산 (예를 들어, 알라닌, 발린, 루이신, 이소루이신, 프롤린, 페 닐알라닌, 메티오닌, 트립토판), β-분지 측쇄를 갖는 아미노산 (예를 들어, 트레오닌, 발린, 이소루이신) 및 방향족 측쇄를 갖는 아미노산 (예를 들어, 티로신, 페닐알라닌, 트립토판, 히스티딘)이 포함된다. 따라서, MP 단백질에서 예상되는 비필수 아미노산 잔기는 바람직하게는 동일한 측쇄 군으로부터의 다른 아미노산 잔기로 치환된다. 별법으로, 다른 실시양태에서 포화 돌연변이유발법 등에 의해 MP 코딩 서열의 전부 또는 일부를 따라 무작위적으로 돌연변이를 도입할 수 있으며, MP 활성을 보유하는 돌연변이체를 확인하기 위해, 생성된 돌연변이체를 본원에 기재된 MP 활성에 대하여 스크리닝 할 수 있다. 서열목록에서 홀수 서열 번호의 서열들 중 한 뉴클레오티드 서열을 돌연변이유발시킨 다음, 코딩된 단백질을 재조합적으로 발현시킬 수 있고, 예를 들어 본원에 기재된 분석법을 이용하여 단백질의 활성을 결정할 수 있다 (실시예 8을 참조).
상기 기재된 MP 단백질을 코딩하는 핵산 분자 이외에도, 본 발명의 다른 측면은 그와 안티센스인 단리된 핵산 분자에 관한 것이다. "안티센스" 핵산은 단백질을 코딩하는 "센스" 핵산에 상보적인 뉴클레오티드 서열을 포함하며, 예를 들어 이중 가닥 DNA 분자의 코딩 가닥에 대해 상보적이거나 mRNA 서열에 대해 상보적인 뉴클레오티드 서열 등이 있다. 따라서, 안티센스 핵산은 센스 핵산과 수소 결합할 수 있다. 안티센스 핵산은 전체 MP 코딩 가닥과 또는 그의 일부에만 상보적일 수 있다. 한 실시양태에서, 안티센스 핵산 분자는 MP 단백질을 코딩하는 뉴클레오티드 서열의 코딩 가닥의 "코딩 영역"에 대해 안티센스이다. 용어 "코딩 영역"은 아 미노산 잔기로 번역되는 코돈을 포함하는 뉴클레오티드 서열의 영역 (예를 들어, 서열 1 (RXA02229)의 전체 코딩 영역은 뉴클레오티드 1에서 825를 포함함)을 의미한다. 다른 실시양태에서, 안티센스 핵산 분자는 MP를 코딩하는 뉴클레오티드 서열의 코딩 가닥의 "비코딩 영역"에 대해 안티센스이다. 용어 "비코딩 영역"은 아미노산으로 번역되지 않는, 코딩 영역의 양측에 있는 5' 및 3' 서열 (즉, 5' 및 3' 비번역 영역이라고도 함)을 의미한다.
본원에 개시된 MP를 코딩하는 코딩 가닥 서열 (예를 들어, 이 서열은 서열목록에서 홀수 서열 번호로 기재되어 있음)을 기초로 하여, 왓슨 (Watson)과 크릭 (Crick)의 염기쌍 규칙에 따라 본 발명의 안티센스 핵산을 고안할 수 있다. 이 안티센스 핵산 분자는 MP mRNA의 전체 코딩 영역에 대해 상보적일 수 있지만, 더욱 바람직하게는 MP mRNA의 코딩 또는 비코딩 영역의 일부에만 안티센스인 올리고뉴클레오티드이다. 예를 들어, 안티센스 올리고뉴클레오티드는 MP mRNA의 번역 개시 부위 주변의 영역에 대해 상보적일 수 있다. 안티센스 올리고뉴클레오티드의 길이는 예를 들어, 뉴클레오티드 약 5, 10, 15, 20, 25, 30, 35, 40, 45 또는 50개이다. 본 발명의 안티센스 핵산은 당업계에 공지된 방법을 이용하는 화학적 합성법 및 효소적 라이게이션 반응법을 이용하여 제작할 수 있다. 예를 들어, 자연 발생적인 뉴클레오티드, 또는 분자의 생물학적 안정성을 증가시키거나, 안티센스와 센스 핵산 사이에 형성된 이중 가닥의 물리적인 안정성을 증가시키기 위해 고안된 다양하게 변형된 뉴클레오티드를 사용하여 (예를 들어, 포스포로티오에이트 유도체 및 아크리딘 치환된 뉴클레오티드가 사용될 수 있음), 안티센스 핵산 (예를 들어, 안티센스 올리고뉴클레오티드)을 화학적으로 합성할 수 있다. 안티센스 핵산을 생성하는데 사용될 수 있는 변형된 뉴클레오티드의 예로는 5-플루오로우라실, 5-브로모우라실, 5-클로로우라실, 5-요오도우라실, 히포크산틴, 크산틴, 4-아세틸시토신, 5-(카르복시히드록실메틸)우라실, 5-카르복시메틸아미노메틸-2-티오우리딘, 5-카르복시메틸아미노메틸우라실, 디히드로우라실, β-D-갈락토실퀘오신, 이노신, N6-이소펜테닐아데닌, 1-메틸구아닌, 1-메틸이노신, 2,2-디메틸구아닌, 2-메틸아데닌, 2-메틸구아닌, 3-메틸시토신, 5-메틸시토신, N6-아데닌, 7-메틸구아닌, 5-메틸아미노메틸우라실, 5-메톡시아미노메틸-2-티오우라실, β-D-만노실퀘오신, 5'-메톡시카르복시메틸우라실, 5-메톡시우라실, 2-메틸티오-N6-이소펜테닐아데닌, 우라실-5-옥시아세트산(v), 비부톡소신, 슈도 (pseudo)우라실, 퀘오신, 2-티오시토신, 5-메틸-2-티오우라실, 2-티오우라실, 4-티오우라실, 5-메틸우라실, 우라실-5-옥시아세트산, 메틸에스테르, 우라실-5-옥시아세트산(v), 5-메틸-2-티오우라실, 3-(3-아미노-3-N-2-카르복시프로필)우라실, (acp3)w 및 2,6-디아미노퓨린이 포함된다. 또는, 핵산이 안티센스 방향으로 서브클로닝된 발현 벡터 (즉, 삽입된 핵산으로부터 전사되는 RNA는 원하는 표적 핵산에 대해 안티센스 방향임. 하기 서브섹션에 추가로 설명되어 있음)를 사용하여 안티센스 핵산을 생물학적으로 생성시킬 수 있다.
본 발명의 안티센스 핵산 분자는 통상적으로 세포에 투여되거나 이들이 MP 단백질을 코딩하는 세포내 mRNA 및(또는) 게놈 DNA와 혼성화하거나 결합하도록 계내 생성되어, 전사 및(또는) 번역 억제 등과 같이 단백질의 발현을 억제한다. 혼성화는 안정한 이중 나선을 형성하는 통상의 뉴클레오티드 상보성에 의한 것이거 나, 예를 들어, 이중 나선의 메이저 그루브에서 특이적 상호작용을 통해 DNA 이중 나선과 결합하는 안티센스 핵산 분자의 경우에 의한 것일 수 있다. 안티센스 분자는, 예를 들어 안티센스 핵산 분자를 세포 표면의 수용체 또는 항원과 결합하는 펩티드 또는 항체에 연결시킴으로써, 그가 선택된 세포 표면에서 발현되는 수용체 또는 항원과 특이적으로 결합하도록 변형시킬 수 있다. 또한, 본원에 기재된 벡터를 사용하여 안티센스 핵산 분자를 세포에 전달시킬 수도 있다. 안티센스 분자의 충분한 세포내 농도를 달성하기 위해서는, 안티센스 핵산 분자가 강력한 원핵세포, 바이러스 또는 진핵세포 프로모터의 조절을 받는 벡터 구조물인 것이 바람직하다.
다른 실시양태에서, 본 발명의 안티센스 핵산 분자는 α-아노머 핵산 분자이다. α-아노머 핵산 분자는 상보적 RNA와 특이적 이중 가닥 하이브리드를 형성하며, 이 때 통상의 β-유닛과는 대조적으로, 가닥들은 서로에 대해 평행한 상태로 있다 (문헌 [Gaultier et al. (1987) Nucleic Acids. Res. 15:6625-6641]). 안티센스 핵산 분자는 2'-o-메틸리보뉴클레오티드 (문헌 [Inoue et al. (1987) Nucleic Acids Res. 15:6131-6148]) 또는 키메라 RNA-DNA 유사체 (문헌 [Inoue et al. (1987) FEBS Lett. 215:327-330])를 포함할 수도 있다.
다른 실시양태에서, 본 발명의 안티센스 핵산 분자는 리보자임이다. 리보자임은 리보뉴클레아제 활성을 갖는 촉매성 RNA 분자이며, 그와 상보적 영역을 갖는 mRNA 등의 단일 가닥 핵산을 절단할 수 있다. 따라서, 리보자임 (예를 들어, 햄머헤드 (hammerhead) 리보자임 (문헌 [Haselhoff and Gerlach (1988) Nature 334:585-591]에 기재되어 있음))을 사용하여 MP mRNA 전사체를 촉매적으로 절단함 으로써 MP mRNA의 번역을 억제할 수 있다. 본원에 개시된 MP DNA의 뉴클레오티드 서열 (즉, 서열 1 (RXA02229))을 기초로 하여 MP-코딩 핵산에 대해 특이성을 갖는 리보자임을 고안할 수 있다. 예를 들어, 테트라히메나 (Tetrahymena) L-19 IVS RNA의 유도체를 제작할 수 있으며, 여기서 활성 부위의 뉴클레오티드 서열은 MP-코딩 mRNA에서 절단되는 뉴클레오티드 서열에 대해 상보적이다 (예를 들어, 세치 (Cech) 등의 미국 특허 제4,987,071호 및 세치 (Cech) 등의 미국 특허 제5,116,742호 참조). 또는, MP mRNA를 사용하여 RNA 분자의 푸울로부터 특정 리보뉴클레아제 활성을 갖는 촉매성 RNA를 선별해낼 수 있다 (예를 들어, 문헌 [Bartel, D. and Szostak, J.W. (1993) Science 261:1411-1418] 참조).
별법으로, MP 뉴클레오티드 서열의 조절 영역 (예를 들어, MP 프로모터 및(또는) 인핸서)에 대해 상보적인 뉴클레오티드 서열을 표적화하여 표적 세포에서 MP 유전자의 전사를 방지하는 삼중 나선 구조를 형성시킴으로써 MP 유전자의 발현을 억제시킬 수 있다 (통상적으로, 문헌 [Helene, C. (1991) Anticancer Drug Des. 6(6):569-84], 문헌 [Helene, C. et al. (1992) Ann.N.Y. Acad.Sci.660:27-36] 및 문헌 [Maher, L.J. (1992) Bioassays 14(12):807-15] 참조).
B. 재조합 발현 벡터 및 숙주 세포
본 발명의 다른 측면은 벡터, 바람직하게는 MP 단백질 (또는 그의 일부)을 코딩하는 핵산을 함유하는 발현 벡터에 관한 것이다. 본원에서 사용된 바와 같이, 용어 "벡터"란 그에 연결된 다른 핵산을 수송할 수 있는 핵산을 지칭한다. 벡터의 한 유형으로 "플라스미드"란 추가의 DNA 절편이 라이게이션될 수 있는 환형 이중 가닥 DNA 고리를 의미한다. 벡터의 다른 유형인 바이러스 벡터는 추가의 DNA 절편을 바이러스 게놈 내로 라이게이션시킬 수 있다. 특정 벡터는 도입된 숙주 세포 내에서 자율적으로 복제될 수 있다 (예를 들면, 박테리아 복제 기점을 가진 박테리아 벡터 및 포유류의 에피솜 벡터). 다른 벡터 (예를 들면, 포유류의 비-에피솜 벡터)는 숙주 세포 내로 도입된 후 숙주 게놈 내로 통합되어 숙주 게놈을 따라 함께 복제된다. 또한, 특정 벡터는 작동가능하게 연결된 유전자의 발현을 지시할 수 있다. 본 명세서에서는 그러한 벡터를 "발현 벡터"로 언급한다. 일반적으로, 재조합 DNA 기술에서 사용하는 발현 벡터는 대개 플라스미드의 형태를 갖는다. 플라스미드는 가장 일반적으로 사용되는 벡터 형태이기 때문에, 본 명세서에서는 "플라스미드"와 "벡터"를 혼용할 수 있다. 그러나, 본 발명에는 동등한 기능을 제공하는 바이러스 벡터 (예를 들면, 복제 결손 레트로바이러스, 아데노 바이러스 및 아데노-관련 바이러스)와 같은 다른 형태의 발현 벡터도 포함된다.
본 발명의 재조합 발현 벡터는 본 발명의 핵산을 숙주 세포 내에서 핵산의 발현에 적합한 형태로 포함하며, 적합한 형태란 상기 재조합 발현 벡터가 발현용 숙주 세포를 기준으로 선택된 하나 이상의 조절 서열 (발현되는 핵산 서열에 작동가능하게 연결됨)을 함유하고 있음을 의미한다. 재조합 발현 벡터 내에서, "작동가능하게 연결된"이란, 원하는 뉴클레오티드 서열 (예를 들면, 시험관내 전사/번역 시스템 내 또는 벡터가 숙주 세포 내로 도입되는 경우 숙주 세포 내에서)이 발현가능하도록 조절 서열(들)에 연결된 것을 의미한다. 용어 "조절 서열"이란, 프로모터, 리프레서 결합 부위, 활성자 결합 부위, 인핸서 및 기타 발현 조절 요소 (예를 들면, 종결자, 폴리아데닐화 신호, 또는 mRNA 2차 구조와 관련된 다른 요소)를 포함하는 것으로 한다. 그러한 조절 서열은, 예를 들어 문헌 [Goeddel; Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, CA (1990)]에 기술되어 있다. 조절 서열에는 다수의 숙주 세포 유형 내에서 뉴클레오티드 서열이 구성적으로 발현되도록 하는 것과 특정 숙주 세포 내에서만 뉴클레오티드 서열이 발현되도록 하는 것이 포함된다. 바람직한 조절 서열에는, 예를 들어 박테리아에서 바람직하게 사용되는 cos-, tac-, trp-, tet-, trp-tet-, lpp-, lac-, lpp-lac-, lacIq-, T7-, T5-, T3-, gal-, trc-, ara-, SP6-, arny, SPO2, λ-PR- 또는 λPL와 같은 프로모터가 있다. 추가의 조절 서열에는, 예를 들어 ADC1, MFα, AC, P-60, CYC1, GAPDH, TEF, rp28, ADH와 같은 효모 및 진균으로부터의 프로모터, CaMV/35S, SSU, OCS, lib4, usp, STLS1, B33, nos나 우비퀴틴- 또는 파세올린-프로모터와 같은 식물로부터의 프로모터가 있다. 또한 인공 프로모터도 사용할 수 있다. 당업자는 발현 벡터가 형질전환되는 숙주 세포의 선택, 목적 단백질의 발현 정도 등과 같은 인자들에 따라 다르게 고안될 수 있음을 이해할 것이다. 본 발명의 발현 벡터는 숙주세포에 도입됨으로써 본 명세서에 기술된 핵산에 의해 코딩되는 융합 단백질 또는 펩티드 (예를 들면, MP 단백질, MP 단백질의 돌연변이 형태, 융합 단백질 등)를 비롯한 단백질 또는 펩티드를 생산할 수 있다.
본 발명의 재조합 발현 벡터는 원핵 또는 진핵 세포에서의 MP 단백질 발현용으로 고안될 수 있다. 예를 들어, MP 유전자는 코리네박테리움 글루타미쿰과 같은 박테리아 세포, 곤충 세포 (바쿨로바이러스 발현 벡터 사용), 효모 및 다른 진균류 세포 (문헌 [Romanos, M.A. et al. (1992) "Foreign gene expression in yeast: a review", Yeast 8:423-488; van den Hondel, C.A.M.J.J. et al. (1991) "Heterologous gene expression in filamentous fungi" in: More Gene Manipulations in Fungi, J.W. Bennet & L.L. Lasure, eds., p.396-428: Academic Press: San Diego; and van den Hondel, C.A.M.J.J. & Punt, P.J. (1991) "Gene transfer systems and vector development for filamentous fungi, in: Applied Molecular Genetics of Fungi, Peberdy, J.F. et al., eds., p. 1-28, Cambridge University Press: Cambridge] 참조), 조류 및 다세포 식물 세포 (문헌 [Schmidt, R. and Willmitzer, L. (1988) High efficiency Agrobacterium tumefactiens-mediated transformation of Arabidopsis thaliana leaf and cotyledon explants" Plant Cell Rep.:583-586] 참조) 또는 포유류 세포 내에서 발현될 수 있다. 적합한 숙주 세포는 문헌 [Goeddel, Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, CA (1990)]에 더 기술되어 있다. 별법으로, 예를 들어 T7 프로모터 조절 서열 및 T7 중합효소를 사용하여 재조합 발현 벡터를 시험관 내에서 전사 및 번역시킬 수 있다.
원핵 세포 내에서의 단백질 발현은 대체로 융합 또는 비-융합 단백질의 발현을 지시하는 구성적 또는 유도가능한 프로모터 함유 벡터로 수행한다. 융합 벡터는 그의 코딩되는 단백질에, 일반적으로는 재조합 단백질의 아미노 말단 뿐 아니라 C-말단에 다수의 아미노산을 부가하거나, 그 단백질의 적절한 영역 내에서 다수의 아미노산을 융합시킨다. 그러한 융합 벡터는 전형적으로 다음의 세 가지 목적, 1) 재조합 단백질의 발현 증가, 2) 재조합 단백질의 가용성 증가, 및 3) 친화성 정제에서 리간드로서 작용함에 의한 재조합 단백질 정제 상의 용이함을 위한 것이다. 대개 융합 발현 벡터 내에서는 융합 부분과 재조합 단백질의 접합부에 단백질 절단 부위가 도입되어 있어서 융합 단백질을 정제한 후 융합 부분으로부터 재조합 단백질을 분리할 수 있다. 그러한 효소 및 그의 동족 인식 서열에는 응고인자 Xa, 트롬빈 및 엔테로키나제 등이 있다.
전형적인 융합 발현 벡터에는 pGEX (Pharmacia Biotech Inc; 문헌 [Smith, D.B. and Johnson, K.S. (1988) Gene 67:31-40] 참조), pMAL (New England Biolabs, Beverly, MA) 및 pRIT5 (Pharmacia, Piscataway, NJ) 등이 있으며, 이들은 각각 글루타티온-S-트랜스퍼라제 (GST), 말토스 E 결합 단백질 또는 프로틴 A (protein A)를 표적 재조합 단백질에 융합시킨다. 한 실시양태에서는 MP 단백질의 코딩 서열을 pGEX 발현 벡터 내로 클로닝하여 N-말단 내지 C-말단에 GST-트롬빈 절단 부위-X 단백질을 함유하는 융합 단백질 코딩 벡터를 생성하였다. 상기 융합 단백질은 글루타티온-아가로스 수지를 사용하는 친화성 크로마토그래피에 의해 정제할 수 있다. GST에 융합되지 않은 재조합 MP 단백질은 융합 단백질을 트롬빈으로 절단함으로써 얻을 수 있다.
적합한 유도가능한 비-융합 대장균 발현 벡터의 예로는 pTrc (문헌 [Amann et al.,(1988) Gene 69:301-315] 참조), pLG338, pACYC184, pBR322, pUC18, pUC19, pKC30, pRep4, pHS1, pHS2, pPLc236, pMBL24, pLG200, pUR290, pINIII113-B1, λ gt11, pBdCl 및 pET 11d (문헌 [Studier et al., Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, California (1990) 60-89] 및 문헌 [Pouwels et al., eds. (1985) Cloning Vectors. Elsevier: New York IBSN 0 444 904018] 참조)가 있다. pTrc 벡터에서 표적 유전자는 trp-lac 혼성 융합 프로모터로부터 숙주 RNA 중합효소에 의한 전사에 의해 발현된다. pET 11d 벡터에서 표적 유전자는 T7 gn 10-lac 융합 프로모터로부터 동시 발현된 바이러스 RNA 중합효소 (T7 gn1)가 매개하는 전사에 의해 발현된다. 이 바이러스 중합효소는 숙주 균주 BL21(DE3) 또는 HMS174(DE3)에 존재하는, lacUV 5 프로모터의 전사 조절 하에 T7 gn1 유전자를 함유하는 λ프로파지로부터 공급된다. 다양한 박테리아의 형질전환을 위해 적절한 벡터를 선택할 수 있다. 예를 들어, 플라스미드 pIJ101, pIJ364, pIJ702 및 pIJ361은 스트렙토마이세스 (Streptomyces)를 형질전환시키는데 유용한 것으로 알려진 반면, 플라스미드 pUB110, pC194 또는 pBD214는 바실루스 (Bacillus) 종을 형질전환시키는데 적합하다. 코리네박테리움 내로 유전 정보를 전달하는데 사용되는 플라스미드에는 pHM1519, pBL1, pSA77 또는 pAJ667 (문헌 [Pouwels et al.,eds.(1985) Cloning Vectors. Elsevier: New York IBSN 0 444 904018] 참조) 등이 있다.
재조합 단백질의 발현을 극대화하는 한가지 전략은 재조합 단백질에 대한 단백질 분해성 절단력이 손상된 숙주 박테리아 내에서 상기 단백질을 발현시키는 것이다 (문헌 [Gottesman, S., Gene Expression Technology: Methods in Enzymology 185, Academic Press, San Diego, California (1990) 119-128] 참조). 다른 전략 으로는 발현 벡터 내로 삽입되는 핵산의 핵산 서열을 변형하여 각각의 아미노산에 대한 개별적인 코돈이 발현을 위해 선택된 박테리아 (예를 들어, 코리네박테리움 글루타미쿰)가 선호하는 코돈이 되도록 하는 것이 있다 (문헌 [Wada et al.(1992) Nucleic Acids Res. 20:2111-2118] 참조). 이처럼 본 발명의 핵산 서열을 변형하는 것은 표준 DNA 합성 기술에 의해 수행될 수 있다.
다른 실시양태에서, MP 단백질 발현 벡터는 효모 발현 벡터이다. 효모 사카로마이세스 세레비지애 (Saccharomyces cerevisiae)의 발현 벡터의 예로는 pYepSec1 (문헌 [Baldari, et al.,(1987) Embo J.6:229-234), 2μ, pAG-1, Yep6, Yep13, pEMBLYe23, pMFa (문헌 [Kurjan and Herskowitz,(1982) Cell 30:933-943) 참조), pJRY88 (문헌 [Shultz et al.,(1987) Gene 54:113-123] 참조) 및 pYES2 (Invitrogen Corporation, San Diego, CA) 등이 있다. 사상 진균류와 같은 다른 진균류용으로 적절한 벡터 및 벡터의 제조 방법으로는 문헌 [van den Hondel, C.A.M.J.J. & Punt, P.J. (1991) "Gene transfer systems and vector development for filamentous fungi, in:Applied Molecular Genetics of Fungi, J.F. Peberdy, et al.,eds., p. 1-28, Cambridge University Press: Cambridge] 및 문헌 [Pouwels et al.,eds.(1985) Cloning Vectors. Elsevier: New York (IBSN 0 444 904018)]에 상술된 것들이 포함된다.
별법으로, 바쿨로바이러스 발현 벡터를 사용하여 본 발명의 MP 단백질을 곤충 세포 내에서 발현시킬 수 있다. 배양된 곤충 세포 (예를 들면, Sf 9 세포)에서의 단백질 발현용 바쿨로바이러스 벡터에는 pAc계 (문헌 [Smith et al. (1983) Mol. Cell Biol. 3:2156-2165] 참조) 및 pVL계 (문헌 [Lucklow and Summers (1989) Virology 170:31-39] 참조) 등이 있다.
다른 실시양태에서는 단세포 식물 세포 (예를 들어, 조류) 또는 고등 식물 (예를 들면, 작물 식물과 같은 종자 식물)로부터의 식물 세포 내에서 본 발명의 MP 단백질을 발현시킬 수 있다. 식물 발현 벡터의 예로는 문헌 [Becker, D., Kemper, E., Schell, J. and Masterson, R. (1992) "New plant binary vectors with selectable markers located proximal to the left border", Plant Mol. Biol. 20: 1195-1197], 문헌 [Bevan, M.W. (1984) "Binary Agrobacterium vectors for plant transformation", Nucl. Acid. Res. 12: 8711-8721]에 상술된 것들이 포함되며 pLGV23, pGHlac+, pBIN19, pAK2004 및 pDH51 (문헌 [Pouwels et al., eds. (1985) Cloning Vectors. Elsevier: New York IBSN 0 444 904018] 참조)가 포함된다.
또 다른 실시양태에서는 포유류 발현 벡터를 사용하여 포유류 세포 내에서 본 발명의 핵산을 발현시킨다. 포유류 발현 벡터의 예로는 pCDM8 (문헌 [Seed, B. (1987) Nature 329:840] 참조) 및 pMT2PC (문헌 [Kaufman et al. (1987) EMBO J. 6:187-195] 참조) 등이 있다. 포유류 세포를 사용하는 경우, 발현 벡터의 조절 기능은 대개 바이러스 조절 요소에 의한 것이다. 예를 들어, 일반적으로 사용되는 프로모터는 폴리오마, 아데노바이러스 2, 사이토메갈로바이러스 및 시미안 바이러스 40으로부터 유래된 것이다. 원핵 세포 및 진핵 세포 둘 다에 적합한 다른 발현계에 대해서는 문헌 [Chapters 16 and 17 of Sambrook, J., Fritsh, E.F., and Maniatis, T. Molecular Cloning: A Laboratory Manual. 2nd. ed. Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989]을 참조한다.
다른 실시양태에서, 재조합 포유류 발현 벡터는 특정 세포 유형에서의 차별적인 핵산 발현이 가능하도록 한다 (예를 들면, 조직-특이적 조절 요소가 핵산을 발현시키는데 사용된다). 조직-특이적 조절 요소는 당업계에 공지되어 있다. 적합한 조직-특이적 프로모터의 예로는 알부민 프로모터 (간-특이적; 문헌 [Pinkert et al. (1987) Genes Dev. 1:268-277] 참조), 림프양-특이적 프로모터 (문헌 [Calame and Eaton (1988) Adv. Immunol. 43:235-275] 참조), 특히 T 세포 수용체의 프로모터 (문헌 [Winoto and Baltimore (1989) EMBO J. 8:729-733] 참조)와 면역글로불린의 프로모터 (문헌 [Banerji et al. (1983) Cell 33:729-740], 문헌 [Queen and Baltimore (1983) Cell 33:741-748] 참조), 뉴런-특이적 프로모터 (예를 들면, 뉴로필라멘트 프로모터; 문헌 [Byrne and Ruddle (1989) PNAS 86:5473-5477] 참조), 췌장-특이적 프로모터 (문헌 [Edlund et al. (1985) Science 230:912-916] 참조) 및 유선(乳腺)-특이적 프로모터 (예를 들면, 유장(乳漿) 프로모터; 미국 특허 제4,873,316호 및 유럽 출원 번호 제264,166호 참조) 등이 있으나, 이에 제한되지 않는다. 또한, 발생-조절 프로모터, 예를 들어 쥐과 hox 프로모터 (문헌 [Kessel and Gruss (1990) Science 249:374-379] 참조) 및 α-페토프로틴 프로모터 (문헌 [Campes and Tilghman (1989) Genes Dev. 3:537-546] 참조)도 포함된다.
본 발명은 안티센스 방향으로 발현 벡터 내에서 클로닝된 본 발명의 DNA 분 자를 함유하는 재조합 발현 벡터를 추가로 제공한다. 즉, 상기 DNA 분자는 MP mRNA에 대해 안티센스인 RNA 분자의 (상기 DNA 분자의 전사에 의한) 발현이 가능하도록 조절 서열에 작동가능하게 연결된다. 안티센스 방향으로 클로닝된 핵산에 작동가능하게 연결된 조절 서열은 예를 들어, 바이러스 프로모터 및(또는) 인핸서처럼 다양한 세포 유형에서 안티센스 RNA 분자가 지속적으로 발현되도록 하는 것으로 선택할 수 있으며, 또는 안티센스 RNA가 구성적, 조직-특이적 또는 세포형 특이적으로 발현되도록 하는 조절 서열을 선택할 수도 있다. 안티센스 발현 벡터는 고효율의 조절 영역의 조절 하에서 안티센스 핵산을 생산하는 재조합 플라스미드, 파지미드 또는 약독화 바이러스의 형태일 수 있으며, 그 활성은 상기 벡터가 도입된 세포 유형에 의해 결정될 수 있다. 안티센스 유전자를 사용하여 유전자 발현을 조절하는 것에 대해서는 문헌 [Weintraub, H. et al., Antisense RNA as a molecular tool for genetic analysis, Reviews - Trends in Genetics, Vol. 1(1) 1986]을 참조한다.
본 발명의 다른 측면은 본 발명의 재조합 발현 벡터가 도입된 숙주 세포에 관한 것이다. 용어 "숙주 세포" 및 "재조합 숙주 세포"는 본 명세서에서 혼용되고 있다. 그러한 용어는 특정 대상 세포를 지칭할 뿐만 아니라 그러한 세포의 자손 또는 잠재적인 자손도 의미하는 것으로 이해한다. 세대를 지나면서 돌연변이나 환경의 영향으로 인해 임의의 변형이 나타날 수 있기 때문에, 사실 그러한 자손은 부모 세포와 동일하지 않지만, 여전히 본 명세서에서 사용하는 용어의 범위에 포함된다.
숙주 세포는 임의의 원핵 세포 또는 진핵 세포일 수 있다. 예를 들어, MP 단백질은 코리네박테리움 글루타미쿰과 같은 박테리아 세포, 곤충 세포, 효모 또는 포유류 세포 (예를 들어, 차이니스 햄스터 난소 세포 (CHO) 또는 COS 세포) 내에서 발현될 수 있다. 다른 적합한 숙주 세포는 당업자에게 공지되어 있다. 본 발명의 핵산 및 단백질 분자를 위한 숙주세포로서 용이하게 사용할 수 있는 코리네박테리움 글루타미쿰 관련 미생물이 표 3에 기재되어 있다.
벡터 DNA는 통상적인 형질전환 또는 형질감염 기술을 통해 원핵 또는 진핵 세포 내로 도입될 수 있다. 본원에서 사용된 용어 "형질전환" 및 "형질감염", "접합" 및 "형질도입"이란, 이종 핵산 (예를 들면, 선형 DNA 또는 RNA (예를 들면, 선형화 벡터이거나, 또는 벡터 없는 단독 유전자 구조물)) 또는 벡터 형태의 핵산 (예를 들면, 플라스미드, 파지, 파스피드, 파지미드, 트랜스포손 또는 다른 DNA)을 숙주 세포 내에 도입하는 다양한 공지 기술을 의미하는 것이며, 여기에는 인산 칼슘 또는 염화 칼슘 동시 침전법, DEAE-덱스트란-매개 형질감염법, 리포펙션법 (lipofection), 천연 감응법 (natural competence), 화학물질 매개 전달법, 또는 전기천공법 등이 포함된다. 숙주 세포를 형질전환 또는 형질감염시키는데 적합한 방법은 문헌 [Sambrook et al. (Molecular Cloning: A Laboratory Manual. 2nd, ed., Cold Spring Harbor Laboratory, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989)] 및 다른 실험 매뉴얼에서 찾을 수 있다.
포유류 세포의 안정적 형질감염에 대해서는, 발현 벡터와 이용된 형질감염 기술에 따라, 단지 일부 소수 세포만이 그의 게놈 내로 외래 DNA를 통합한다는 것 이 알려져 있다. 이들 통합체를 확인하고 선별하기 위해, 일반적으로 선택가능한 표지 (예를 들면, 항생제 내성)를 코딩하는 유전자를 목적 유전자와 함께 숙주 세포 내로 도입시킨다. 바람직한 선택가능한 표지에는 G418, 하이그로마이신 및 메토트렉세이트와 같은 약물 내성을 부여하는 것들이 포함된다. 선택가능한 표지를 코딩하는 핵산은 MP 단백질을 코딩하는 그 벡터 상에서 숙주 세포 내로 도입될 수 있으며, 또는 별도의 벡터 상에서 도입될 수도 있다. 도입된 핵산이 안정적으로 형질감염된 세포는 약물 선택법을 통해 확인할 수 있다 (예를 들면, 선택가능한 표지 유전자가 혼입된 세포는 생존할 것이나, 그렇지 않은 다른 세포는 사멸한다).
상동성 재조합 미생물을 제조하기 위해서, 결실, 부가 또는 치환을 도입시켜 MP 유전자를 변형 (예를 들면, 기능을 파괴)시킨 MP 유전자의 적어도 일부를 함유하는 벡터를 제조한다. 바람직하게는 이 MP 유전자는 코리네박테리움 글루타미쿰 MP 유전자이지만, 관련 박테리아로부터의 상동체뿐만 아니라 포유류, 효모 또는 곤충 기원으로부터의 상동체일 수도 있다. 바람직한 실시양태에서, 상기 벡터는 상동성 재조합에 의해 내인성 MP 유전자가 기능적으로 파괴 (즉, 더이상 기능적 단백질을 코딩하지 않음, "녹아웃 (knock-out)" 벡터로도 지칭됨)되도록 고안된다. 별법으로, 상기 벡터는 상동성 재조합에 의해 내인성 MP 유전자가 돌연변이되거나 달리 변형되었지만 여전히 기능적 단백질을 코딩 (즉, 상류 조절 영역이 변형되어 내인성 MP 단백질의 발현이 변형될 수 있음)하도록 고안된다. 상동성 재조합 벡터에는 변경된 MP 유전자 일부의 5' 및 3'의 측면에 MP 유전자의 추가적인 핵산이 위치하여 벡터에 의해 운반된 외인성 MP 유전자와 미생물 내의 내인성 MP 유전자 사이 에 상동성 재조합이 일어나도록 한다. 추가된 측면 MP 핵산은 내인성 유전자와 성공적으로 상동성 재조합 되기에 충분한 길이를 갖는다. 전형적으로, 수 킬로베이스의 측면 DNA (5' 및 3' 말단 둘 다)가 상기 벡터 내에 포함된다 (예를 들어, 상동성 재조합 벡터에 대해 기술하는 문헌 [Thomas, K.R., and Capecchi, M.R. (1987) Cell 51:503] 참조). 상기 벡터는 (예를 들면, 전기천공법에 의해) 미생물 내로 도입되고, 도입된 MP 유전자와 내인성 MP 유전자가 상동성 재조합된 세포를 공지된 기술에 의해 선별한다.
다른 실시양태에서, 도입된 유전자의 발현을 조절할 수 있는 것으로 선택된 시스템을 함유하는 재조합 미생물을 제조할 수 있다. 예를 들어, 벡터 상에 lac 오페론의 조절을 받는 MP 유전자가 포함된 경우에는 오직 IPTG의 존재 하에서만 MP 유전자가 발현될 수 있다. 그러한 조절 시스템은 당업계에 공지되어 있다.
다른 실시양태에서, 숙주 세포 내의 내인성 MP 유전자를 (예를 들면, 상동성 재조합 또는 당업계에 공지된 다른 유전적 수단에 의해) 파괴하여 그의 단백질 산물이 발현되지 않게 한다. 다른 실시양태에서, 숙주 세포 내의 도입된 MP 유전자 또는 내인성 MP 유전자는 하나 이상의 점 돌연변이, 결실 또는 역위에 의해 변경되지만, 여전히 기능적 MP 단백질을 코딩한다. 다른 실시양태에서, 미생물 내에 있는 하나 이상의 조절 영역 (예를 들면, 프로모터, 리프레서 또는 인듀서)이 (예를 들면, 결실, 절단, 역위 또는 점 돌연변이에 의해) 변경되어 MP 단백질의 발현이 변한다. 당업자라면, 상기 기술한 MP 유전자 및 단백질 변형을 하나 이상 함유한 숙주 세포가 본 발명의 방법을 이용하여 용이하게 생성될 수 있으며 이들이 본 발 명에 포함되는 것임을 이해할 것이다.
배양물 중의 원핵 또는 진핵 숙주 세포와 같은 본 발명의 숙주 세포는 MP 단백질의 생산 (즉, 발현)에 이용된다. 따라서, 본 발명은 본 발명의 숙주 세포를 이용한 MP 단백질의 생산 방법을 추가로 제공한다. 한 실시양태에서, 상기 방법은 본 발명의 (MP 단백질을 코딩하는 재조합 발현 벡터가 도입되거나, 야생형 또는 변형된 MP 단백질을 코딩하는 유전자가 게놈 내로 도입된) 숙주 세포를 MP 단백질이 생산될 때까지 적합한 배지에서 배양하는 것을 포함한다. 다른 실시양태에서, 상기 방법은 상기 배지 또는 숙주 세포로부터 MP 단백질을 단리하는 것을 추가로 포함한다.
C. 단리된 MP 단백질
본 발명의 다른 측면은 단리된 MP 단백질 및 생물학적으로 활성인 그의 일부에 관한 것이다. "단리된" 또는 "정제된" 단백질 또는 생물학적으로 활성인 그의 일부는 재조합 DNA 기술에 의해 생산된 경우 실질적으로 세포내 물질이 없으며, 또는 화학적으로 합성된 경우에는 실질적으로 화학적 전구체나 다른 화학 물질이 없다. 용어 "실질적으로 세포내 물질이 없는 것"이란, 천연적으로 또는 재조합에 의해 MP 단백질을 생산하는 세포의 세포 구성 물질로부터 상기 단백질을 분리한 MP 단백질 제제를 포함한다. 한 실시양태에서, 용어 "실질적으로 세포내 물질들이 없는 것"은 비-MP 단백질 (본 명세서에서 "오염 단백질"로도 언급됨) 함량이 약 30% 미만 (건 중량), 바람직하게는 약 20% 미만, 더욱 바람직하게는 약 10% 미만, 가장 바람직하게는 약 5%인 MP 단백질 제제를 포함한다. 또한, MP 단백질 또 는 생물학적으로 활성인 그의 일부가 재조합에 의해 생산되는 경우, 실질적으로 배양 배지가 없는 것이 바람직하다. 즉, 배양 배지 함량이 약 20 부피% 미만, 더욱 바람직하게는 약 10 부피% 미만, 가장 바람직하게는 5 부피% 미만으로 나타나는 단백질 제제가 바람직하다. 용어 "실질적으로 화학적 전구체나 다른 화학 물질이 없는 것"이란, MP 단백질의 합성에 관여한 화학적 전구체 또는 다른 화학 물질로부터 상기 단백질을 분리한 MP 단백질 제제를 포함한다. 한 실시양태에서, 용어 "실질적으로 화학적 전구체나 다른 화학 물질이 없는 것"은 화학적 전구체 또는 비-MP 화학 물질의 함량이 약 30% 미만 (건 중량), 바람직하게는 약20% 미만, 더욱 바람직하게는 약 10% 미만, 가장 바람직하게는 약 5%인 MP 단백질 제제를 포함한다. 바람직한 실시양태에서, 단리된 단백질 또는 생물학적으로 활성인 그의 일부에는 그 MP 단백질이 유래된 생물로부터의 오염 단백질이 없다. 전형적으로, 그러한 단백질은 예를 들어 코리네박테리움 글루타미쿰과 같은 미생물 내에서 코리네박테리움 글루타미쿰 MP 단백질의 재조합 발현에 의해 생산된다.
본 발명의 단리된 MP 단백질 또는 그의 일부는 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드 또는 트레할로스 대사 경로의 효소 반응을 촉매할 수 있거나, 표 1에 기재된 활성 중 하나 이상을 갖는다. 바람직한 실시양태에서, 상기 단백질 또는 그의 일부는 본 발명의 아미노산 서열과 충분히 상동성인 (예를 들면, 서열 목록에서 짝수 서열 번호로 기재된 서열) 아미노산 서열을 포함하며, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드 또는 트레할로스 대사 경로의 효소 반응을 촉매할 수 있는 능력을 유지한다. 상기 단백질 의 일부는 바람직하게는 본 명세서에서 기술한 것처럼 생물학적으로 활성인 일부이다. 다른 바람직한 실시양태에서, 본 발명의 MP 단백질은 서열 목록에서 짝수 서열 번호로 기재된 아미노산 서열을 갖는다. 다른 바람직한 실시양태에서, MP 단백질은 본 발명의 뉴클레오티드 서열 (예를 들면, 서열 목록에서 홀수 서열 번호로 기재된 서열)에 혼성화하는 (예를 들면, 엄격 조건 하에서 혼성화하는) 뉴클레오티드 서열에 의해 코딩되는 아미노산 서열을 갖는다. 다른 바람직한 실시양태에서, MP 단백질은 본 발명의 핵산 서열 또는 그의 일부 중 하나와 약 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59% 또는 60% 이상, 바람직하게는 약 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69% 또는 70% 이상, 더욱 바람직하게는 약 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79% 또는 80% 이상, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89% 또는 90% 이상, 또는 91%, 92%, 93%, 94% 이상이고, 더욱 바람직하게는 약 95%, 96%, 97%, 98%, 99% 또는 그 이상의 상동성이 있는 뉴클레오티드 서열에 의해 코딩되는 아미노산 서열을 갖는다. 또한, 상기 언급된 값에 중간값인 동일성 값 및 범위 (예를 들어, 70 내지 90% 동일 또는 80 내지 95% 동일)는 본 발명에 포함되는 것으로 한다. 예를 들어, 상기 언급한 임의의 값을 최대값 및(또는) 최소값의 조합으로 사용한 동일성 값의 범위는 본 발명에 포함된다. 또한, 본 발명의 바람직한 MP 단백질은 본 명세서에 기술된 MP 활성을 하나 이상 보유하는 것이 바람직하다. 예를 들어, 본 발명의 바람직한 MP 단백질은 본 발명의 뉴클레오티드 서열에 혼성화 (예를 들면, 엄격 조건 하에서의 혼성화)하는 뉴클레오티드 서열에 의해 코딩된 아미노산 서열을 포함하며, 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스 대사 경로의 효소 반응을 촉매할 수 있거나, 표 1에 기재된 활성 중 하나 이상을 가질 수 있다.
다른 실시양태에서, MP 단백질은 실질적으로 본 발명의 아미노산 서열 (예를 들면, 서열 목록에서 짝수 서열 번호로 기재된 서열)과 상동성이며, 상기 서브섹션 I에서 상술한 것처럼 천연 변이나 돌연변이유발로 인하여 아미노산 서열이 다름에도 본 발명의 아미노산 서열 중 하나의 단백질의 기능적 활성을 보유한다. 따라서, 다른 실시양태에서, MP 단백질은 본 발명의 전체 아미노산 서열과의 상동성이 약 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59% 또는 60% 이상, 바람직하게는 약 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69% 또는 70% 이상, 더욱 바람직하게는 약 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79% 또는 80% 이상, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89% 또는 90% 이상, 또는 91%, 92%, 93%, 94% 이상이고, 더욱 바람직하게는 약 95%, 96%, 97%, 98%, 99% 또는 그 이상인 아미노산 서열을 포함하며, 본 명세서에 기술된 MP 활성 중 하나 이상을 가지고 있다. 또한, 상기 언급한 값에 중간값인 동일성 값 및 범위 (예를 들어, 70 내지 90% 동일 또는 80 내지 95% 동일)는 본 발명에 포함되는 것으로 한다. 예를 들어, 상기 언급한 임의의 값을 최대값 및(또는) 최소값의 조합으로 사용한 동일성 값의 범위는 본 발명에 포함된다. 다른 실시양태에서, 본 발명은 본 발명의 전체 아미노산 서열과 실질적으로 상동성인 전장의 코리네박테리움 글루타미쿰 단백질에 관한 것이다.
MP 단백질의 생물학적으로 활성인 일부는 MP 단백질의 아미노산 서열 (예를 들면, 서열 목록에서 짝수 서열 번호로 기재된 서열)로부터 유래된 아미노산 서열을 포함하거나 MP 단백질과 상동성인 단백질의 아미노산 서열을 포함하며 전장 MP 단백질 또는 MP 단백질과 상동성이며 하나 이상의 MP 단백질 활성을 보이는 전장 단백질보다 적은 수의 아미노산을 함유한다. 전형적으로, 생물학적으로 활성인 일부 (펩티드, 예를 들어 5, 10, 15, 20, 30, 35, 36, 37, 38, 39, 40, 50, 100 또는 그 이상의 아미노산 길이를 갖는 펩티드)은 MP 단백질의 하나 이상의 활성을 갖는 도메인 또는 모티프를 포함한다. 또한, 상기 단백질의 다른 영역이 결실되어 생물학적으로 다른 활성을 갖는 일부를 재조합 기술에 의해 제조할 수 있으며 본원에서 기술한 하나 이상의 활성을 측정할 수 있다. 바람직하게는, MP 단백질의 생물학적으로 활성인 일부는 생물학적 활성이 있는 하나 이상의 선택된 도메인/모티프 또는 그의 일부를 포함한다.
MP 단백질은 바람직하게는 재조합 DNA 기술에 의해 생산된다. 예를 들어, 상기 단백질을 코딩하는 핵산 분자는 발현 벡터 (상기 기술된 바와 같음) 내로 클로닝되고, 상기 발현 벡터는 숙주 세포 (상기 기술된 바와 같음) 내로 도입되고, MP 단백질은 상기 숙주 세포 내에서 발현된다. 그후 상기 MP 단백질은 표준 단백질 정제 기술을 이용하여 적절한 정제 단계를 통해 세포로부터 단리될 수 있다. 재조합 발현과는 별법으로, MP 단백질, 폴리펩티드 또는 펩티드는 표준 펩티드 합성 기술을 이용하여 화학적으로 합성할 수 있다. 또한, 천연 MP 단백질은, 예를 들어 본 발명의 MP 단백질 또는 그의 일부를 사용한 표준 방법에 의해 생산될 수 있는 항-MP 항체를 사용하여 세포 (예를 들면, 내피 세포)로부터 단리할 수 있다.
또한 본 발명은 MP 키메라 또는 융합 단백질을 제공한다. 본 명세서에서 사용된 MP "키메라 단백질" 또는 "융합 단백질"은 비-MP 폴리펩티드에 작동가능하게 연결된 MP 폴리펩티드를 포함한다. "MP 폴리펩티드"란 MP에 상응하는 아미노산 서열을 갖는 폴리펩티드를 지칭하며, "비-MP 폴리펩티드"란 실질적으로 MP 단백질과 상동성이 없는 단백질, 예를 들어 MP 단백질과 다르며 동일한 또는 상이한 생물로부터 유래된 단백질에 상응하는 아미노산 서열을 갖는 폴리펩티드를 의미한다. 융합 단백질에서, 용어 "작동가능하게 연결된"이란, MP 폴리펩티드 및 비-MP 폴리펩티드가 프레임 내에서 서로 융합된 것을 의미한다. 상기 비-MP 폴리펩티드는 MP 폴리펩티드의 N-말단 또는 C-말단에 융합될 수 있다. 예를 들어 한 실시양태에서, 융합 단백질은 MP 서열이 GST 서열의 C-말단에 융합된 GST-MP 융합 단백질이다. 그러한 융합 단백질은 재조합 MP 단백질의 정제를 용이하게 할 수 있다. 다른 실시양태에서, 융합 단백질은 그의 N-말단에 이종 신호 서열을 함유하는 MP 단백질이다. 특정한 숙주 세포 (예를 들면, 포유류 숙주 세포) 내에서, MP 단백질의 발현 및(또는) 분비는 이종 신호 서열을 이용함으로써 증가될 수 있다.
바람직하게는, 본 발명의 MP 키메라 또는 융합 단백질은 표준 재조합 DNA 기술에 의해 생산된다. 예를 들어, 별개의 폴리펩티드 서열을 코딩하는 DNA 단편을 통상적인 기술에 따라, 예를 들어 라이게이션을 위해 블런트-말단 또는 엇갈린 (stagger-ended) 말단을 이용는데, 적절한 말단을 만들기 위해 제한 효소로 절단하고, 경우에 따라 접착 말단을 채워 넣고, 바람직하지 않은 연결을 피하기 위해 알 칼라인 포스파타제를 처리하고, 효소로 라이게이션시킴으로써 동일 프레임 내에 함께 라이게이션시킨다. 다른 실시양태에서, 융합 유전자는 자동 DNA 합성기 등을 사용하는 통상적인 기술로 합성될 수 있다. 별법으로, 2개의 연속된 유전자 단편 사이에 상보적인 오버행을 생성케하는 앵커 프라이머를 사용하여 유전자 단편을 PCR 증폭할 수 있으며, 이는 추후 어닐링되고 재증폭되어 키메라 유전자 서열을 생성한다 (예를 들어, 문헌 [Current Protocols in Molecular Biology, eds. Ausubel et al. John Wiley & Sons: 1992] 참조). 또한, 융합 부분 (예를 들면, GST 폴리펩티드)을 이미 코딩하고 있는 발현 벡터들이 많이 시판되고 있다. MP 코딩 핵산을 그러한 발현 벡터 내로 클로닝시켜 융합 부분을 MP 단백질로 동일 프레임 내에서 연결시킬 수 있다.
MP 단백질의 상동체는 돌연변이유발법, 예를 들어 분별 점 돌연변이 또는 MP 단백질의 트런케이션에 의해 생성될 수 있다. 본원에서 사용된 바와 같이, 용어 "상동체"란, MP 단백질의 활성에 대한 아고니스트 또는 길항제로 작용하는 MP 단백질의 변이체 형태를 지칭하는 것이다. MP 단백질 아고니스트의 생물학적 활성은 MP 단백질의 것과 실질적으로 동일하거나, 그에 버금갈 수 있다. MP 단백질의 길항제는 예를 들어 MP 단백질을 포함하는 MP 캐스캐이드의 하류 또는 상류 구성원에 경쟁적으로 결합함으로써 MP 단백질 자연 발생 형태의 활성 하나 이상을 억제할 수 있다. 따라서, 본 발명의 코리네박테리움 글루타미쿰 MP 단백질 및 그의 상동체는 MP 단백질이 이 미생물 내에서 역할을 하는 대사 경로 하나 이상의 활성을 조절할 수 있다.
다른 실시양태에서, 상기 MP 단백질의 상동체는 MP 단백질 돌연변이체 (예를 들면, 트런케이션 돌연변이체)의 조합 라이브러리를 MP 단백질 아고니스트 또는 길항제 활성에 대해 스크리닝함으로써 확인할 수 있다. 한 실시양태에서, MP 변이체의 혼재된 (variegated) 라이브러리는 핵산 수준에서의 조합 돌연변이유발법으로 생성되며, 혼재된 유전자 라이브러리에 의해 코딩된다. MP 변이체의 혼재된 라이브러리는 예를 들어 합성 올리고뉴클레오티드 혼합물을 유전자 서열에 효소적으로 라이게이션시켜 잠재적 MP 서열의 축퇴 (degenerate) 세트가 개별적인 폴리펩티드로서 발현가능하게 하거나, 별법으로 그 안에 MP 서열의 세트를 함유한 거대 융합 단백질 (예를 들면, 파지 디스플레이)로서 발현가능하게 할 수 있다. 다양한 방법들을 사용하여 축퇴 올리고뉴클레오티드 서열로부터 잠재적 MP 상동체의 라이브러리를 생산할 수 있다. 자동 DNA 합성기를 사용하여 축퇴 유전자 서열을 화학적으로 합성할 수 있고, 그 다음, 상기 합성 유전자를 적절한 발현 벡터 내로 라이게이션시킬 수 있다. 유전자 축퇴 세트를 이용하면 원하는 세트의 가능한 MP 서열을 코딩하는 모든 서열을 하나의 혼합물 내에 제공할 수 있다. 축퇴 올리고뉴클레오티드를 합성하는 방법은 당업계에 공지되어 있다 (예를 들면, 문헌 [Narang, S.A. (1983) Tetrahedron 39:3], 문헌 [Itakura et al. (1984) Annu. Rev. Biochem. 53:323], 문헌 [Itakura et al. (1983) Science 198:1056], 문헌 [Ike et al. (1983) Nucleic Acid Res. 11:477] 참조).
또한, MP 단백질 코딩 유전자의 단편 라이브러리를 이용하여 MP 단백질 상동체에 대한 스크리닝 및 그 후의 선별을 위한 MP 단편의 혼재된 집단을 생성할 수 있다. 한 실시양태에서, 새김눈 (nick)이 분자 당 약 한 번만 일어나는 조건 하에서 뉴클레아제를 MP 코딩 서열의 이중 가닥 PCR 단편에 처리하고, 상기 이중 가닥 DNA를 변성시키고, 상기 DNA를 탈변성 (renaturation)시켜 다른 새김눈 생성물로부터의 센스/안티센스 쌍을 포함할 수 있는 이중 가닥 DNA를 형성케하고, S1 뉴클레아제를 처리하여 재형성된 이중 가닥으로부터 단일 가닥 부분을 제거하고, 생성된 단편 라이브러리를 발현 벡터 내로 라이게이션시킴으로써 코딩 서열 단편의 라이브러리를 제조할 수 있다. 이 방법에 의해, 다양한 크기를 갖는 MP 단백질의 N-말단, C-말단 및 내부 단편을 코딩하는 발현 라이브러리를 유도할 수 있다.
점 돌연변이 또는 트런케이션에 의해 만들어진 조합 라이브러리의 유전자 산물 스크리닝 및 선택된 특성을 갖는 유전자 산물에 대한 cDNA 라이브러리 스크리닝을 위한 몇몇 기술이 당업계에 공지되어 있다. 그러한 기술은 MP 상동체의 조합 돌연변이유발에 의해 생성된 유전자 라이브러리를 신속하게 스크리닝하는 데 사용할 수 있다. 가장 널리 사용되는 기술로서, 거대 유전자 라이브러리를 스크리닝하기 위한 고처리능 분석에서 사용가능한 기술로는 대표적으로 유전자 라이브러리를 복제가능한 발현 벡터 내로 클로닝하고, 생성된 벡터 라이브러리로 적절한 세포를 형질전환시키고, 원하는 활성의 검출이 검출되는 유전자 산물을 코딩하는 벡터의 단리를 용이하게 하는 조건 하에서 조합 유전자를 발현시키는 것을 포함한다. 라이브러리 내 기능성 돌연변이의 빈도를 증가시키는 새로운 기술인 재귀적 앙상블 돌연변이유발법 (Recursive ensemble mutagenesis) (REM)을 스크리닝 분석 시험과 함께 사용하여 MP 상동체를 확인할 수 있다 (문헌 [Arkin and Yourvan (1992) PNAS 89:7811-7815], 문헌 [Delgrave et al. (1993) Protein Engineering 6(3):327-331] 참조).
다른 실시양태에서, 당업계에 공지된 방법을 사용하는 세포 기재 분석법으로 혼재된 MP 라이브러리를 분석할 수 있다.
D. 본 발명의 용도 및 방법
본원에 기재한 핵산 분자, 단백질, 단백질 상동체, 융합 단백질, 프라이머, 벡터 및 숙주세포는 코리네박테리움 글루타미쿰 및 관련 생물의 확인, 코리네박테리움 글루타미쿰과 관련된 생물의 게놈 맵핑, 코리네박테리움 글루타미쿰의 목적 서열의 확인 및 위치 규명, 진화 연구, 기능에 필요한 MP 단백질 부위의 결정, MP 단백질 활성의 조절, MP 경로의 활성 조절, 및 정밀 화학물질과 같은 원하는 화합물의 세포내 생성 조절 등의 방법 중 하나 이상에 사용할 수 있다.
본 발명의 MP 핵산 분자는 다양한 용도를 갖는다. 첫째, 코리네박테리움 글루타미쿰 또는 그와 밀접하게 관련된 것일 수 있는 생물의 존재 여부 확인에 사용할 수 있다. 또한, 혼합된 미생물 집단에서 코리네박테리움 글루타미쿰 또는 그와 밀접하게 관련된 것일 수 있는 미생물의 존재 여부를 확인하는 데 사용할 수 있다. 본 발명은 단일 또는 혼합된 미생물 집단의 배양물에서 추출한 게놈 DNA를 엄격 조건하에서 코리네박테리움 글루타미쿰에 고유한 유전자 영역에 걸친 프로브를 사용하여 탐침함으로써 상기 생물의 존재 여부를 확인할 수 있는 다수의 코리네박테리움 글루타미쿰 유전자의 핵산 서열을 제공한다. 코리네박테리움 글루타미쿰 그 자체는 인간에게 병원성이 아니지만, 코리네박테리움 디프테리아와 같은 인간 병원체 인 종과 관련이 있다. 코리네박테리움 디프테리아는 국부 및 전신성 병변을 수반하여 급속도로 진행되는 급성 발열 감염인 디프테리아의 원인균이다. 이러한 질병에서는, 호흡관 상부에 국소 병변이 발생하고 상피 세포에 괴사성 손상을 수반하고, 바실러스가 독소를 분비하여 상기 병변을 통해 신체 말단에 감염되기 쉬운 조직으로 퍼지게 된다. 심장, 근육 말초 신경, 부신, 신장, 간 및 비장을 비롯한 상기 조직에서 단백질 합성의 억제에 의해 발생하는 퇴행성 변화는 질병의 전신성 병리 현상을 일으킨다. 디프테리아는 아프리카, 아시아, 동유럽 및 구 소련 연합의 독립 국가를 비롯한 세계의 여러 지역에서 높은 발병율을 유지하고 있다. 동유럽 및 구 소련의 독립 국가에서 계속되는 유행성 디프테리아로 1990년 이래 5,000명 이상이 사망했다.
한 실시양태에서, 본 발명은 개체에서 코리네박테리움 디프테리아의 존재 여부 또는 활성을 확인하는 방법을 제공한다. 본 발명은 개체에서 본 발명의 1종 이상의 핵산 또는 아미노산 서열 (서열목록에서 홀수 또는 짝수 서열 번호로 각각 나타냄)을 검출함으로써 개체에서 코리네박테리움 디프테리아의 존재 여부 또는 활성을 검출하는 것을 포함한다. 코리네박테리움 글루타미쿰과 코리네박테리움 디프테리아는 관련있는 박테리아이며, 코리네박테리움 글루타미쿰의 많은 핵산 및 단백질 분자는 코리네박테리움 디프테리아의 핵산 및 단백질 분자와 상동성이 있으므로 개체에서 코리네박테리움 디프테리아를 검출하는데 사용할 수 있다.
또한, 본 발명의 핵산 및 단백질 분자는 게놈의 특정 영역의 마커로 기능을 한다. 이러한 기능은 게놈 맵핑뿐 아니라 코리네박테리움 글루타미쿰 단백질의 기 능 연구에서도 유용성이 있다. 예를 들어, 코리네박테리움 글루타미쿰 게놈을 절단하여 단편을 DNA 결합 단백질과 인큐베이션시켜, 코리네박테리움 글루타미쿰의 특정 DNA 결합 단백질이 결합하는 게놈 영역을 확인할 수 있다. 단백질에 결합하는 영역은 또한 본 발명의 핵산 분자, 바람직하게는 용이하게 검출할 수 있는 표지로 탐침할 수 있다. 이와 같은 게놈 단편에 대한 핵산 분자의 결합으로 코리네박테리움 글루타미쿰의 게놈 맵에 단편의 위치를 정할 수 있으며, 상이한 효소로 여러번 수행하는 경우 단백질이 결합하는 핵산 서열을 신속하고 용이하게 결정한다. 또한, 본 발명의 핵산 분자는 관련 종의 서열과 충분한 상동성을 가질 수 있어서 브레비박테리움 락토페르멘툼 (Brevibacterium lactofermentum)과 같은 관련 박테리아의 게놈 맵을 작성하기 위한 마커로 사용할 수 있다.
또한, 본 발명의 MP 핵산 분자는 진화 및 단백질 구조 연구에 유용하다. 본 발명의 분자가 관여하는 대사 과정은 매우 다양한 원핵 및 진핵 박테리아에 의해 이용된다. 다른 생물과 유사한 효소를 코딩하는 핵산 분자 서열과 본 발명의 핵산 분자의 서열을 비교함으로써 생물의 진화 관련성을 평가할 수 있다. 유사하게, 이러한 비교로 서열 영역의 보존 여부를 평가할 수 있으며, 이러한 보존 영역은 효소 기능에 필수적인 단백질 영역을 결정하는데 도움이 될 수 있다. 이러한 결정 방법은 단백질 공학에 유용하며, 단백질 기능의 손실없이 유발된 돌연변이에 내성을 가질 수 있는 지를 나타낼 수 있다.
본 발명의 MP 핵산 분자의 조작으로 야생형 MP 단백질과는 상이한 기능을 갖는 MP 단백질을 제조할 수 있다. 이러한 단백질은 효율 또는 활성이 개선될 수 있 으며, 정상 세포보다 과량으로 존재할 수 있거나 효율 또는 활성이 감소될 수 있다.
본 발명은 단백질 자체 또는 기질 또는 MP 단백질의 결합 파트너와 상호작용시키거나 본 발명의 MP 핵산 분자의 전사 또는 번역을 조절함으로써 MP 단백질의 활성을 조절하는 분자를 스크리닝하는 방법을 제공한다. 상기 방법에서, 본 발명의 1종 이상의 MP 단백질을 발현하는 생물을 1종 이상의 시험 화합물과 접촉시켜 MP 단백질의 활성 또는 발현수준에 대한 각각의 시험 화합물의 효과를 평가한다.
코리네박테리움 글루타미쿰의 대규모 발효 배양물로부터 단리한, 원하는 정밀 화학물질이 아미노산, 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 또는 트레할로스인 경우, 재조합 유전 메카니즘으로 본 발명의 단백질 1종 이상의 활성 또는 활성 효율을 조절하여 상기 정밀 화학물질 중 하나의 생성에 직접 영향을 미칠 수 있다. 예를 들어, 원하는 아미노산에 관한 생합성 경로 효소의 경우, 효소 (다수의 유전자 카피의 존재 포함)의 활성 또는 효율을 개선시켜, 그 원하는 아미노산의 생산 효율 또는 생산성을 증가시켜야 한다. 아미노산에 관한 생합성 경로의 효소 합성이 원하는 아미노산의 합성과 경쟁 관계에 있는 경우, 이 효소의 효율 또는 활성을 임의로 감소 (유전자 결실 포함)시켜, 중간체 화합물 및(또는) 에너지에 관한 경쟁 감소에 기인한 그 원하는 아미노산의 생산 효율 또는 생산성 증가를 유발해야 한다. 원하는 아미노산에 관한 분해 경로 효소의 경우, 그 효소의 활성 또는 효율을 임의로 감소시켜, 이로 인한 원하는 생성물의 분해 감소에 기인하여 그 원하는 생성물의 생성 효율 또는 수율이 향상되도록 해야 한다. 마지막 으로, 원하는 아미노산의 생합성에 관여하는 효소가 더이상 피드백 억제할 수 없도록 이 효소를 돌연변이유발시켜 원하는 아미노산의 생산 효율 또는 수율을 증가시켜야 한다. 비타민, 보조인자, 영양제, 뉴클레오티드, 뉴클레오시드, 및 트레할로스 대사에 관여하는 본 발명의 생합성 및 분해 효소에도 마찬가지가 적용되어야 한다.
유사하게, 원하는 정밀 화학물질이 상기 언급한 화합물 중 하나가 아닐 경우, 본 발명의 단백질 중 하나의 활성 조절은 코리네박테리움 글루타미쿰의 대규모 배양물로부터의 화합물 생산 효율 및(또는) 수율에 영향을 미칠 수 있다. 임의의 생물의 대사 경로는 밀접하게 상호연관되어 있어서, 한 경로에서 사용되는 중간체가 종종 다른 경로에 의해 공급된다. 상이한 대사 과정으로부터의 화합물의 세포내 수준을 기준으로 효소 발현 및 기능을 조절할 수 있고, 아미노산 및 뉴클레오티드 등 기본적인 성장에 필요한 분자들의 세포내 수준은 대규모 배양시 미생물 생존력에 크게 영향을 줄 수 있다. 그러므로, 예를 들면, 더이상 피드백 억제를 하지 않거나, 효율 또는 교체율 (turnover)이 개선되도록 아미노산 생합성 효소를 조절하여 아미노산 1종 이상의 세포내 수준을 증가시킬 수 있다. 그 다음, 이렇게 증가된 아미노산 푸울 (pool)은 단백질 합성에 필요한 분자들의 공급 뿐 아니라, 수많은 다른 생합성 경로에서 중간체 및 전구체로 이용되는 분자들의 공급 또한 증가시킨다. 특정 아미노산이 세포내에서 제한되는 경우, 이 아미노산의 생성 증가는 세포의 수많은 다른 대사 반응의 수행력을 증가시킬 수 있을 뿐 아니라, 그 세포가 모든 종류의 단백질을 더욱 효과적으로 생성케하고, 가능하다면, 대규모 배양시 그 세포의 전반적인 성장 속도 또는 생존 능력을 증가시킬 수도 있다. 생존력 증가는 발효 배양시 원하는 정밀 화학물질을 생성할 수 있는 수많은 세포들을 개선시켜, 이 화합물의 수율을 증가시킨다. 유사하게, 본 발명의 분해 효소가 원하는 화합물의 생합성에 중요한 세포내 화합물의 분해를 더 이상 촉매하지 못하거나, 덜 효율적으로 촉매하도록, 또는 대규모 배양시 이 세포가 더욱 효과적으로 성장하고 번식할 수 있도록 이 효소의 활성을 조절할 수 있다. 또한, 본 발명의 특정 분자의 분해 활성을 최적화시키거나 생합성 활성을 감소시켜 코리네박테리움 글루타미쿰으로부터의 특정 정밀 화학물질 생성에 유익한 영향을 줄 수 있음은 강조되어야 한다. 예를 들어, 원하는 화합물의 생합성 경로에서 1종 이상의 중간체에 관해 경쟁적 경로에 있는 생합성 효소의 활성 효율을 감소시키면, 더 많은 상기 중간체들이 원하는 생성물로의 전환에 이용될 수 있을 것이다.
원하는 화학물질의 수율을 증가시키기 위한 MP 단백질의 돌연변이유발법에 관한 상기 목록은 한정적인 것이 아니며, 이러한 방법의 변형법은 당업자에게 자명할 것이다. 이러한 메카니즘에 의해, 본 발명의 핵산 및 단백질 분자를 돌연변이된 MP 핵산 및 단백질 분자를 발현하는 코리네박테리움 글루타미쿰 또는 관련 균주의 제조에 이용하여 원하는 화합물의 수율, 생산성 및(또는) 생산 효율을 개선시킨다. 상기 원하는 화합물은 생합성 경로의 최종 생성물 및 자연 발생 대사 경로의 중간체 뿐 아니라 코리네박테리움 글루타미쿰 대사에서는 본래 일어나지 않으나 본 발명의 코리네박테리움 글루타미쿰 균주에 의해서는 생산되는 분자를 포함하는, 코리네박테리움 글루타미쿰에 의해 생산되는 모든 천연 생성물일 수 있다.
또한, 본 발명은 하기 실시예에 의해 예시되나, 이에 한정되는 것으로 해석해서는 안된다. 본원 전반에 걸쳐 인용된 모든 참고 문헌, 특허 출원, 특허, 공개된 특허 출원의 모든 내용, 표 및 서열목록은 본원에서 참고로 도입된다.
Figure 112006079122708-pat00001
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Figure 112006079122708-pat00049
Figure 112006079122708-pat00050
Figure 112006079122708-pat00051
Figure 112006079122708-pat00052
Figure 112006079122708-pat00053
Figure 112006079122708-pat00054
Figure 112006079122708-pat00055
Figure 112006079122708-pat00056
Figure 112006079122708-pat00057
Figure 112006079122708-pat00058
Figure 112006079122708-pat00059
Figure 112006079122708-pat00060
Figure 112006079122708-pat00061
Figure 112006079122708-pat00062
Figure 112006079122708-pat00063
Figure 112006079122708-pat00064
Figure 112006079122708-pat00065
Figure 112006079122708-pat00066
Figure 112006079122708-pat00067
Figure 112006079122708-pat00068
Figure 112006079122708-pat00069
Figure 112006079122708-pat00070
Figure 112006079122708-pat00071
Figure 112006079122708-pat00072
Figure 112006079122708-pat00073
Figure 112006079122708-pat00074
Figure 112006079122708-pat00075
Figure 112006079122708-pat00076
Figure 112006079122708-pat00077
실시예
실시예 1: 코리네박테리움 글루타미쿰 ATCC 13032의 전체 게놈 DNA의 프렙
BHI 배지 (Difco 제품) 중의 코리네박테리움 글루타미쿰 (ATCC 13032) 배양물을 30℃에서 격렬히 진탕시키면서 밤새 성장시켰다. 원심분리하여 세포를 회수하여 상층액은 버리고, 세포를 5 ml 완충액-I (배양물 처음 부피의 5%에 해당함-나타낸 모든 부피는 배양 부피 100 ml에 대해 계산한 값임) 중에 재현탁했다. 완충액-I의 조성은 다음과 같았다: 140.34 g/L 수크로스, 2.46 g/L MgS04 ×7 H2O, 10 ml/L KH2PO4 용액 (100 g/L, KOH를 사용하여 pH 6.7로 조절), 50 ml/L M12 농축물 (10 g/L (NH4)2SO4, 1 g/L NaCl, 2 g/L MgSO4 ×7 H2O, 0.2 g/L CaCl2, 0.5 g/L 효모 추출물 (Difco 제품), 10 ml/L 미량 원소 혼합물 (200 mg/L FeSO4 ×H2O, 10 mg/L ZnSO4 ×7 H2O, 3 mg/L MnCl2 ×4 H2O, 30 mg/L H3BO3, 20 mg/L CoCl2 ×6 H2O, 1 mg/L NiCl2 ×6 H2O, 3 mg/L Na2MoO4 ×2 H2O, 500 mg/L 착화제 (EDTA 또는 시트르산), 100 ml/L 비타민 혼합물 (0.2 mg/L 비오틴, 0.2 mg/L 엽산, 20 mg/L p-아미노 벤조산, 20 mg/L 리보플라빈, 40 mg/L ca-판토테네이트, 140 mg/L 니코틴산, 40 mg/L 피리독솔 히드로클로라이드, 200 mg/L 미오-이노시톨). 상기 현탁액에 리소짐을 최종 농도 2.5 mg/ml로 첨가했다. 37℃에서 대략 4 시간 동안 인큐베이션시킨 다음, 세포벽을 파괴하고 원심분리하여, 원형질체를 수거했다. 펠렛을 5 ml 완충액-I으로 1 회 세척하고, 5 ml TE-완충액 (10 mM 트리스-HCl, 1 mM EDTA, pH 8)으로 1 회 세척했다. 펠렛을 4 ml TE-완충액 중에 재현탁하고, 0.5 ml SDS 용액 (10%) 및 0.5 ml NaCl 용액 (5 M)을 첨가했다. 프로테이나제 K를 최종 농도 200 ㎍/ml로 첨가한 다음, 상기 현탁액을 37℃에서 약 18 시간 동안 인큐베이션시켰다. 표준 방법을 이용하여, 페놀, 페놀-클로로포름-이소아밀알콜 및 클로로포름-이소아밀알콜로 추출하여 DNA를 정제했다. 그 다음, 1/50 부피의 3 M 아세트산 나트륨 및 2 배 부피의 에탄올을 첨가하여 DNA를 침전시킨 후, -20℃에서 30 분 동안 인큐베이션시키고, SS34 회전자 (Sorvall 제품)를 사용한 고속 원심분리기로 12,000 rpm에서 30 분 동안 원심분리했다. 상기 DNA를 20 ㎍/ml RNaseA를 함유한 1 ml TE-완충액 중에 용해시키고, 4℃에서 3 시간 이상 동안 1000 ml TE-완충액 중에 투석했다. 투석 동안, 상기 완충액을 3 회 갈아주었다. 투석된 DNA 용액을 0.4 ml씩 분취하여, 0.4 ml 2 M LiCl 및 0.8 ml 에탄올을 첨가했다. -20℃에서 30 분 동안 인큐베이션시킨 다음, 원심분리 (13,000 rpm, 독일 하나우 헤래우스 소재의 Biofuge Fresco 제품)하여 DNA를 수집했다. DNA 펠렛을 TE-완충액 중에 용해했다. 이 방법으로 프렙된 DNA를 서던 블럿팅 또는 게놈 라이브러리 제작 등의 모든 목적에 이용했다.
실시예 2: 대장균에서 코리네박테리움 글루타미쿰 ATCC13032의 게놈 라이브러리 제
실시예 1에 기재한 바와 같이 프렙된 DNA를 사용하여, 공지되고 수립된 방법 (예를 들면, 문헌 [Sambrook, J. et al. (1989) "Molecular Cloning: A Laboratory Manual", Cold Spring Harbor Laboratory Press] 또는 문헌 [Ausubel, F.M. et al. (1994) "Current Protocols in Molecular Biology", John Wiley & Sons] 참조)에 따라 코스미드 및 플라스미드 라이브러리를 제작했다.
임의의 플라스미드 또는 코스미드를 사용할 수 있었다. 특히, 플라스미드 pBR322 (문헌 [Sutcliffe, J.G. (1979) Proc. Natl. Acad. Sci. USA, 75:3737-3741]); pACYC177 (문헌 [Change & Cohen (1978) J. Bacteriol 134:1141-1156]), pBS 계열의 플라스미드 (pBSSK+, pBSSK- 등; 문헌 [Stratagene, LaJolla, USA]), 또는 SuperCos I (문헌 [Stratagene, LaJolla, USA]) 또는 Lorist6 (문헌 [Gibson, T.J., Rosenthal A. and Waterson, R.H. (1987) Gene 53:283-286]) 등의 코스미드를 사용했다. 구체적으로, 코리네박테리움 글루타미쿰에 사용하기 위한 유전자 라이브러리는 플라스미드 pSL 109 (문헌 [Lee, H.-S. and A.J. Sinskey (1994) J. Microbiol. Biotechnol. 4:256-263])를 사용하여 제작할 수 있다.
실시예 3: DNA 서열분석 및 컴퓨터를 이용한 기능 분석
실시예 2에 기재한 바와 같은 게놈 라이브러리를 사용하여, 표준 방법에 따른 DNA 서열분석, 특히 ABI377 서열분석기를 사용한 쇄 종결 방법 (예를 들면, 문헌 [Fleischman, R.D. et al. (1995) "Whole-genome Random Sequencing and Assembly of Haemophilus Influenzae Rd., Science, 269:496-512)에 의한 DNA 서열분석을 수행했다. 다음의 뉴클레오티드 서열을 갖는 서열분석 프라이머를 사용했다: 5'-GGAAACAGTATGACCATG-3' (서열 1157) 또는 5'-GTAAAACGACGGCCAGT-3' (서열 1158).
실시예 4: 생체내 돌연변이유발법
코리네박테리움 글루타미쿰의 생체내 돌연변이유발법은 완전한 유전 정보 유지 능력이 손상된 대장균 또는 다른 미생물 (예를 들면, 바실루스 종 또는 사카로마이세스 세레비지애 등의 효모)에 플라스미드 (또는 다른 벡터) DNA를 계대접종하여 수행할 수 있다. 전형적인 돌연변이유발 균주는 DNA 복구 시스템에 관한 유전자 (예를 들면, mutHLS, mutD, mutT 등; 참고를 위해서는, 문헌 [Rupp, W.D. (1996) DNA repair mechanisms, in: Escherichia coli and Salmonella, p.2277-2294, ASM: Washington]을 참조한다)에 돌연변이가 있다. 이러한 균주들은 당업자에게 공지되어 있다. 이런 균주의 사용법은 예를 들어, 문헌 [Greener, A. and Callahan, M. (1994) Strategies 7:32-34]에 설명되어 있다.
실시예 5: 대장균과 코리네박테리움 글루타미쿰 사이의 DNA 전달
여러 코리네박테리움 및 브레비박테리움 종은 자율적으로 복제되는 내인성 플라스미드 (예를 들면, pHM1519 또는 pBL1 등)를 함유하고 있다 (이에 관해 살펴보기 위해서는, 예를 들어 문헌 [Martin, J.F. et al. (1987) Biotechnology, 5:137-146]을 참조한다). 대장균 및 코리네박테리움 글루타미쿰에 사용하기 위한 셔틀 벡터는 코리네박테리움 글루타미쿰을 위한 복제 기점 및 코리네박테리움 글루타미쿰으로부터의 적당한 마커를 첨가한, 대장균에 사용하는 표준 벡터 (문헌 [Sambrook, J. et al. (1989), "Molecular Cloning: A Laboratory Manual", Cold Spring Harbor Laboratory Press] 또는 문헌 [Ausubel, F.M. et al. (1994) "Current Protocols in Molecular Biology", John Wiley & Sons])를 사용하여 쉽게 제작할 수 있다. 상기 복제 기점은 코리네박테리움 및 브레비박테리움 종에서 단리한 내인성 플라스미드로부터 얻는 것이 바람직하다. 특히, 상기 종에 관한 형질전환 마커로 사용하는 유전자는 카나마이신 내성 유전자 (예를 들면, Tn5 또는 Tn903 트란스포손 등에서 유래) 또는 클로람페니콜 내성 유전자 (문헌 [Winnacker, E.L. (1987) "From Genes to Clones-Introduction to Gene Technology, VCH, Weinheim])이다. 대장균 및 코리네박테리움 글루타미쿰 모두에서 복제되고, 유전자 과다발현 등을 포함하는 여러 목적에 사용할 수 있는 매우 다양한 셔틀 벡터의 제작법에 관한 수많은 문헌이 있다 (참고를 위해서는, 예를 들어 문헌 [Yoshihama, M. et al. (1985) J. Bacteriol. 162:591-597], 문헌 [Martin J.F. et al. (1987) Biotechnology, 5:137-146] 및 문헌 [Eikmanns, B.J. et al. (1991) Gene, 102:93-98]을 참조한다).
표준 방법을 사용하여, 목적 유전자를 상기 기재된 셔틀 벡터들 중 하나에 클로닝하고 이러한 하이브리드 벡터를 코리네박테리움 글루타미쿰 균주에 도입할 수 있다. 코리네박테리움 글루타미쿰의 형질전환은 원형질체 형질전환법 (문헌 [Kastsumata, R. et al. (1984) J. Bacteriol. 159:306-311]), 전기천공법 (문헌 [Liebl, E. et al. (1989) FEMS Microbiol. Letters, 53:399-303]) 및 특정 벡터가 사용되는 경우에는 접합법 (예를 들면, 문헌 [Schaefer, A et al. (1990) J. Bacteriol. 172:1663-1666]에 기재된 바와 같음)에 의해서도 달성될 수 있다. 또한, 코리네박테리움 글루타미쿰으로부터 플라스미드 DNA를 프렙 (당업계에 공지된 표준 방법을 사용)하고, 이것을 대장균으로 형질전환시켜 코리네박테리움 글루타미쿰에 사용하기 위한 셔틀 벡터를 대장균에 전달할 수도 있다. 이러한 형질전환 단계는 표준 방법을 사용하여 수행할 수 있지만, NM522 (문헌 [Gough & Murray (1983) J. Mol. Biol. 166:1-19]) 등과 같은 Mcr-결핍 대장균 균주를 사용하는 것이 유리하다.
pCGl (문헌 [미국 특허 제4,617,267호]) 또는 이의 단편, 및 경우에 따라 TN903으로부터의 카나마이신 내성 유전자 (문헌 [Grindley, N.D. and Joyce, C.M. (1980) Proc. Natl. Acad. Sci. USA 77 (12):7176-7180])를 포함하는 플라스미드를 사용하여 코리네박테리움 글루타미쿰 균주에서 유전자를 과다발현시킬 수 있다. 또한, 플라스미드 pSL 109 (문헌 [Lee, H.-S. and A.J.Sinskey (1994) J. Microbiol. Biotechnol. 4:256-263])를 사용하여 코리네박테리움 글루타미쿰 균주에서 유전자를 과다발현시킬 수 있다.
복제성 플라스미드를 사용하는 것 이외에도, 유전자 과다발현은 게놈으로의 통합으로 달성될 수도 있다. 코리네박테리움 글루타미쿰 또는 다른 코리네박테리움 또는 브레비박테리움 종에서의 게놈 통합은 게놈 영역(들)과의 상동성 재조합, 제한 엔도뉴클레아제 매개 통합 (REMI) (예를 들어 문헌 [독일 특허 제19823834호] 참조), 또는 트란스포손을 사용하는 등의 공지된 방법으로 수행할 수 있다. 또한, 위치 지정 방법 (예를 들면, 상동성 재조합) 또는 무작위 사건에 기초한 방법 (예를 들면, 트란스포손 돌연변이유발법 또는 REMI)을 사용한 서열의 변형, 삽입, 또는 결실에 의해 조절 영역 (예를 들면, 프로모터, 리프레서, 및(또는) 인핸서)을 변형하여 목적 유전자의 활성을 조절할 수도 있다. 또한, 전사 종결자로 기능하는 핵산 서열을 본 발명의 유전자 하나 이상의 코딩 영역 3'에 삽입할 수도 있다; 이러한 종결자는 당업계에 공지되어 있으며, 예를 들면 문헌 [Winnacker, E.L. (1987) From Genes to Clones-Introduction to Gene Technology. VCH: Weinheim]에 기재되어 있다.
실시예 6: 돌연변이 단백질의 발현 평가
돌연변이된 단백질이 형질전환된 숙주 세포에서 그 단백질의 활성을 관찰한 결과, 상기 돌연변이 단백질이 야생형 단백질과 유사한 방식 및 유사한 양으로 발현된다는 사실을 알아냈다. 돌연변이 유전자의 전사 수준 (유전자 생성물로의 번역에 이용가능한 mRNA 양에 관한 지표)을 확인하는 유용한 방법은 노던 블럿팅 (참고를 위해서는, 예를 들어 문헌 [Ausubel et al. (1988) Current Protocols in Molecular Biology, Wiley: New York]을 참조한다)을 수행하는 것인데, 이는 생물 배양물의 전체 RNA를 추출하여 겔상에서 전개시키고, 이를 안정한 매트릭스로 전달한 후, 목적 유전자에 결합하도록 고안하여 검출가능한 태그 (통상적으로 방사성 또는 화학발광성 태그)로 표지한 프라이머와 인큐베이션시켜, 상기 프로브의 결합 및 그 결합량이 상기 목적 유전자의 mRNA 존재 여부 및 양을 또한 지시하는 방법이다. 이러한 정보는 돌연변이 유전자의 전사 정도에 관한 증거가 된다. 코리네박테리움 글루타미쿰의 세포내 전체 RNA는 예를 들면, 문헌 [Bormann, E.R. et al. (1992) Mol. Microbiol. 6:317-326]에 기재된 것과 같이 당업계에 공지된 여러 방법들을 이용하여 프렙할 수 있다.
이 mRNA로부터 번역된 단백질의 존재 여부 또는 그 상대량을 평가하기 위해서는, 웨스턴 블럿팅과 같은 표준 기술을 사용할 수 있다 (예를 들어, 문헌 [Ausubel et al. (1988) Current Protocols in Molecular Biology, Wiley: New York]을 참조한다). 이 방법에서, 세포내 전체 단백질을 추출하고, 겔 전기영동법으로 분리한 후, 이를 니트로셀룰로스 등과 같은 매트릭스로 전달하여, 원하는 단백질에 특이적으로 결합하는 항체 등의 프로브와 인큐베이션시킨다. 통상적으로, 이 프로브는 쉽게 검출될 수 있는 화학발광성 또는 비색성 표지로 태그된 것이다. 관찰된 표지의 존재 여부 및 양은 그 세포 내에서 원하는 돌연변이 단백질의 존재 여부 및 양을 지시한다.
실시예 7: 유전적으로 변형된 코리네박테리움 글루타미쿰의 성장-배지 및 배양 조
유전적으로 변형된 코리네박테리아를 합성 또는 천연 성장 배지에서 배양한다. 코리네박테리아의 수많은 상이한 성장 배지는 당업계에 공지되어 있으며, 또한 쉽게 이용가능하다 (문헌 [Lieb et al. (1989) Appl. Microbiol. Biotechnol., 32:205-210], 문헌 [von der Osten et al. (1998) Biotechnology Letters, 11:11-16], 문헌 [독일 특허 제4,120,867호], 문헌 [Liebl (1992) "The Genus Corynebacterium", in: The Procaryotes, Volume II, Balows, A. et al., eds. Springer-Verlag]). 상기 배지는 1종 이상의 탄소 공급원, 질소 공급원, 무기염, 비타민 및 미량 원소로 구성된다. 바람직한 탄소 공급원은 단당류, 이당류, 또는 다당류 등의 당이다. 예를 들면, 글루코스, 프룩토스, 만노스, 갈락토스, 리보스, 소르보스, 리불로스, 락토스, 말토스, 수크로스, 라피노스, 녹말 또는 셀룰로스가 매우 훌륭한 탄소 공급원으로 기능한다. 또한, 당 정제시 생성되는 당밀 또는 기타 부산물 등과 같은 복합 화합물 등을 통해 당을 배지에 공급할 수도 있다. 또한, 상이한 탄소 공급원들의 혼합물을 공급하는 것도 유리할 수 있다. 다른 가능한 탄소 공급원은 메탄올, 에탄올, 아세트산 또는 락트산 등의 알콜 및 유기산이다. 질소 공급원은 통상적으로 유기 또는 무기 질소 화합물, 또는 이러한 화합물을 함유하는 물질이다. 질소 공급원의 예로는 암모니아 기체 또는 NH4Cl 또는 (NH4)2SO4, NH40H 등의 암모니아염, 질산염, 우레아, 아미노산 또는 옥수수 침유 (steep liquor), 대두 가루, 대두 단백질, 효모 추출물, 육류 추출물 등의 복합 질소 공급원 등이 있다.
배지에 포함될 수 있는 무기 염 화합물로는 칼슘, 마그네슘, 나트륨, 코발트, 몰리브데늄, 칼륨, 망간, 아연, 구리 및 철의 염산염, 인산염, 또는 황산염 등이 있다. 킬레이트 화합물을 배지에 첨가하여 금속 이온을 용액 상태로 유지할 수 있다. 특히 유용한 킬레이트 화합물로는 카테콜 또는 프로토카테쿠에이트 등의 디히드록시페놀, 또는 시트르산 등의 유기산 등이 있다. 또한, 통상적으로 배지에는 비타민 또는 성장 촉진제 등의 다른 성장 요소가 포함되어 있고, 이들의 예로는 비오틴, 리보플라빈, 티아민, 엽산, 니코틴산, 판토페네이트 및 피리독신 등이 있다. 성장 요소 및 염은 흔히 효모 추출물, 당밀, 옥수수 침유 등과 같은 복합 배지 성분에서 생긴다. 배지 화합물의 정확한 조성은 이후의 실험에 따라 크게 달라지고, 각각의 특정 경우마다 따로 결정된다. 배지의 최적화에 관한 정보는 문헌 ["Applied Microbiol. Physiology, A Practical Approach (eds. P.M. Rhodes, P.F. Stanbury, IRL Press (1997) pp.53-73, ISBN 0 19 963577 3)]에서 찾을 수 있다. 또한, 스탠다드 1 (Merck 제품) 또는 BHI (곡물 속 침출물, DIFCO 제품) 등과 같이 제조 회사로부터의 성장배지 중에서 선택할 수도 있다.
모든 배지 성분들을 열처리 (1.5 bar 및 121℃에서 20 분) 또는 멸균 여과로 멸균시킨다. 이 성분들을 한꺼번에 멸균하거나, 필요에 따라 따로따로 멸균할 수 있다. 모든 배지 성분들은 배양 초기부터 존재하거나, 경우에 따라 연속적으로 또는 배치식으로 (batchwise) 첨가될 수 있다.
배양 조건은 각 실험마다 따로 정의된다. 온도는 15℃와 45℃ 사이의 범위여야 한다. 온도는 일정하게 유지하거나 실험하는 동안 변경할 수 있다. 배지의 pH는 5 내지 8.5의 범위, 바람직하게는 약 7.0이어야 하며, 배지에 완충액을 첨가하여 유지시킬 수 있다. 이러한 목적으로 사용할 수 있는 완충액의 예로는 인산 칼륨 완충액 등이 있다. MOPS, HEPES, ACES 등과 같은 합성 완충액을 대안적으로 사용하거나 동시에 사용할 수 있다. 또한, 배양하는 동안 NaOH 또는 NH4OH를 첨가하여 배양물의 pH를 일정하게 유지시킬 수도 있다. 효모 추출물 등의 복합 배지 성분이 사용되는 경우, 많은 복합 화합물들은 완충 성능이 높기 때문에, 추가의 완충액에 대한 요구를 감소시킬 수 있다. 미생물 배양에 발효기를 사용하는 경우, pH는 암모니아 기체를 사용하여 제어할 수도 있다.
인큐베이션 시간 범위는 통상적으로 수 시간 내지 수 일이다. 이 시간은 브로스 (broth)에 축적되는 생성물의 양이 최대가 되도록 선택한다. 개시한 배양 실험을 상이한 크기의 마이크로타이터 플레이트, 유리관, 유리 플라스크 또는 유리 또는 금속 발효기 등의 다양한 용기에서 수행할 수 있다. 수많은 클론을 스크리닝하기 위해서는, 미생물을 배플 (baffle)이 있거나 없는 마이크로타이터 플레이트, 유리관 또는 진탕 플라스크에서 배양해야 한다. 요구되는 성장 배지를 100 ml 진탕 플라스크에 10% (부피비) 채워 사용하는 것이 바람직하다. 이 플라스크들은 속도 범위 100-300 rpm의 회전 진탕기 상에서 진탕 (진폭 25 mm)되어야 한다. 증발에 의한 손실량은 대기를 습하게 유지함으로써 감소될 수 있다; 별법으로, 증발에 의한 손실량을 정확하게 보정해야 한다.
유전적으로 변형된 클론을 시험하는 경우, 비변형된 대조 클론 또는 임의의 인서트가 없는 기본 플라스미드를 함유하는 대조 클론도 시험해야 한다. 30℃에서 인큐베이션한 CM 플레이트 (10 g/L 글루코스, 2.5 g/L NaCl, 2 g/L 우레아, 10 g/L 폴리펩톤, 5 g/L 효모 추출물, 5 g/L 육류 추출물, 22 g/L 아가, 2 M NaOH을 사용하여 pH 6.8로 조절) 등과 같은 아가 플레이트 상의 세포를 OD600 0.5-1.5이 되도록 배지에 접종한다. 배지 접종은 CM 플레이트로부터의 코리네박테리움 글루타미쿰 세포의 염수 현탁액을 도입하거나, 이 박테리아의 예비배양물을 첨가하여 수행한다.
실시예 8: 돌연변이 단백질의 기능에 관한 시험관내 분석
효소의 활성 및 반응 속도 파라미터의 측정 방법은 당업계에 잘 수립되어 있다. 임의의 주어진 변경된 효소의 활성 측정 실험은 야생형 효소의 비활성(比活性)에 맞추어야 하며, 당업자라면 이를 잘 수행할 수 있다. 효소의 구조, 반응 속도, 원리, 방법, 적용에 관한 구체적인 세부사항 뿐 아니라 효소에 관한 통상적인 개요 및 많은 효소들의 활성 측정 방법의 예를 하기의 참고문헌 등에서 찾을 수 있다: 문헌 [Dixon, M., and Webb, E.C., (1979) Enzymes. Longmans: London; Fersht, (1985) Enzyme Structure and Mechanism. Freeman: New York], 문헌 [Walsh, (1979) Enzymatic Reaction Mechanisms. Freeman: SanFrancisco], 문헌 [Price, N.C., Stevens, L. (1982) Fundamentals of Enzymology. Oxford Univ. Press: Oxford], 문헌 [Boyer, P.D., ed. (1983) The Enzymes, 3rd ed. Academic Press: New York], 문헌 [Bisswanger, H., (1994) Enzymkinetik, 2nd ed. VCH: Weinheim (ISBN 3527300325)], 문헌 [Bergmeyer, H.U., Bergmeyer, J., Grassl, M., eds. (1983-1986) Methods of Enzymatic Analysis, 3rd ed., vol.I-XII, Verlag Chemie: Weinheim], 및 문헌 [Ullmann's Encyclopedia of Industrial Chemistry (1987) vol.A9, "Enzymes". VCH: Weinheim, p.352-363].
DNA에 결합하는 단백질 활성은 DNA 밴드-변위 분석법 (겔 지연 분석법 (gel retardation assays)으로도 지칭됨) 등과 같이 잘 수립된 여러 방법들을 사용하여 측정할 수 있다. 상기 단백질들이 다른 분자들의 발현에 미치는 영향은 리포터 유전자 분석법 (예를 들면, 문헌 [Kolmar, H. et al. (1995) EMBO J. 14:3895-3904] 및 이 문헌에서 인용한 참고 문헌에 기재된 바와 같음)을 사용하여 측정할 수 있다. β-갈락토시다제 등의 효소, 녹색 형광 단백질 및 기타 여러가지를 사용하는 리포터 유전자 시험 시스템은 원핵 세포 및 진핵 세포 모두에의 적용에 대해 공지되어 있으며, 잘 수립되어 있다.
막 수송 단백질의 활성 측정은 문헌 [Gennis, R.B. (1989) "Pores, Channels and Transporters", in Biomembranes, Molecular Structure and Function, Springer: Heidelberg, p.85-137, 199-234, 및 270-322]에 기재된 기술 등에 따라 수행될 수 있다.
실시예 9: 원하는 생성물 생산에 대한 돌연변이 단백질의 영향 분석
코리네박테리움 글루타미쿰에서의 유전적 변형이 원하는 화합물 (예를 들면, 아미노산)의 생산에 미치는 영향은 변형된 미생물을 적당한 조건 (예를 들면, 상기 기재한 바와 같음) 하에 배양하고, 원하는 생성물 (즉, 아미노산)의 생성 증가에 관여한 배지 성분 및(또는) 세포내 성분을 분석하여 평가할 수 있다. 이러한 분석 기술은 당업자에게 공지되어 있으며, 분광분석법, 박층크로마토그래피법, 각종 염색법, 효소적 및 미생물학적 방법, 및 고성능 액체 크로마토그래피법 등과 같은 분석용 크로마토그래피법 등이 있다 (예를 들면, 문헌 [Ullman, Encyclopedia of Industrial Chemistry, vol.A2, p.89-90 및 p.443-613, VCH: Weinheim (1985)], 문헌 [Fallon, A. et al., (1987) "Applications of HPLC in Biochemistry" in: Laboratory Techniques in Biochemistry and Molecular Biology, vol.17], 문헌 [Rehm et al. (1993) Biotechnology, vol.3, Chapter III: "Product recovery and purification", page 469-714, VCH: Weinheim], 문헌 [Belter, P.A. et al. (1988) Bioseparations: downstream processing for biotechnology, John Wiley and Sons], 문헌 [Kennedy, J.F. and Cabral, J.M.S. (1992) Recovery processes for biological materials, John Wiley and Sons], 문헌 [Shaeiwitz, J.A. and Henry, J.D. (1988) Biochemical separations, in: Ulmann's Encyclopedia of Industrial Chemistry, vol.B3, Chapter 11, page 1-27, VCH: Weinheim], 및 문헌 [Dechow, F.J. (1989) Separation and purification techniques in biotechnology, Noyes Publications] 참조).
최종 발효 생성물의 측정 뿐 아니라, 중간체 및 부산물 등과 같이 원하는 화합물의 생성에 이용된 대사 경로 중의 다른 성분들의 분석, 전체적인 화합물 생성 효율의 측정 또한 가능하다. 분석 방법으로는 배지 내의 영양분 (예를 들면, 당, 탄화수소, 질소 공급원, 인산염 및 기타 이온) 함량 측정, 생물집단 (biomass)의 조성 및 증식량 측정, 생합성 경로의 공통 대사물질의 생성 분석, 및 발효 동안에 생성된 기체 측정 등이 있다. 이러한 측정을 위한 표준 방법은 문헌 [Applied Microbial Physiology, A Practical Approach, P.M.Rhodes and P.F.Stanbury, eds., IRL Press, p.103-129, 131-163, 및 165-192 (ISBN:0199635773) 및 이 문헌에서 인용한 참고 문헌]에 약술되어 있다.
실시예 10: 코리네박테리움 글루타미쿰 배양물로부터의 원하는 생성물 정제
당업계에 공지된 각종 방법을 사용하여, 코리네박테리움 글루타미쿰 세포 또는 상기 기재한 배양물의 상층액으로부터 원하는 생성물을 회수할 수 있다. 원하는 생성물이 세포로부터 분비되지 않는 경우, 배양물을 저속 원심분리하여 세포를 수거하고, 기계적인 힘 또는 초음파 등의 표준 기술로 세포를 용균시킬 수 있다. 원심분리로 세포 부스러기를 제거하고, 가용성 단백질을 함유하는 상층액 부분은 남겨 원하는 화합물의 추가의 정제에 사용한다. 코리네박테리움 글루타미쿰 세포로부터 생성물이 분비되는 경우, 배양물을 저속 원심분리하여 세포를 제거하고, 상층액 부분은 남겨 추가의 정제에 사용한다.
상기 두 가지 정제 방법 중 임의의 방법에 의한 상층액 부분을 적당한 수지를 사용한 크로마토그래피에 적용하여, 원하는 분자는 크로마토그래피 수지 상에 남지만 샘플 중의 많은 불순물은 남지 않게 하거나, 불순물들은 수지에 남지만 원하는 분자는 남지 않게 한다. 필요에 따라, 동일하거나 상이한 크로마토그래피 수지를 사용하여 이러한 크로마토그래피 단계를 반복할 수 있다. 당업자라면, 적합한 크로마토그래피 수지를 선택하고 특정 분자의 정제에 대해 가장 효과적으로 이를 적용하는 것에 숙달되어 있을 것이다. 정제된 생성물을 여과법 또는 한외여과법으로 농축시켜, 생성물의 안정성이 최대가 되는 온도에 보관할 수 있다.
당업계에 공지된 정제 방법은 다양하며, 상기 기재한 정제법에 제한되지 않는다. 이러한 정제 기술은 예를 들어 문헌 [Bailey, J.E. & Ollis, D.F. Biochemical Engineering Fundamentals, McGraw-Hill: New York (1986)]에 기재되어 있다.
단리된 화합물의 확인 및 순도는 당업계의 표준 기술로 평가될 수 있다. 여기에는 고성능 액체 크로마토그래피 (HPLC)법, 분광분석법, 염색법, 박층 크로마토그래피법, NIRS, 효소적 분석법, 또는 미생물학적 방법 등이 있다. 상기 분석 방법은 하기 문헌에서 검토된다: 문헌 [Patek et al. (1994) Appl. Environ. Microbiol. 60:133-140], 문헌 [Malakhova et al. (1996) Biotekhnologiya 11:27-32], 문헌 [Schmidt et al. (1998) Bioprocess Engineer. 19:67-70], 문헌 [Ulmann's Encyclopedia of Industrial Chemistry, (1996) vol.A27, VCH: Weinheim, p.89-90, p.521-540, p.540547, p.559-566, p.575-581 및 p.581-587], 문헌 [Michal, G. (1999) Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology, John Wiley and Sons], 및 문헌 [Fallon, A. et al. (1987) Applications of HPLC in Biochemistry in: Laboratory Techniques in Biochemistry and Molecular Biology, vol.17].
실시예 11: 본 발명의 유전자 서열 분석
서열 비교 및 2 가지 서열 사이의 상동성(%) 측정은 당업계에 공지된 기술이며, 이는 문헌 [Karlin and Altschul (1990) Proc. Natl. Acad. Sci. USA 87:2264-68]의 알고리즘을 문헌 [Karlin and Altschul (1993) Proc. Natl. Acad. Sci. USA 90:5873-77]에서와 같이 변형시킨 알고리즘 등의 수리적 알고리즘을 사용하여 수행할 수 있다. 상기 알고리즘을 문헌 [Altschul, et al. (1990) J. Mol. Biol. 215:403-10]의 NBLAST 및 XBLAST 프로그램 (버젼 2.0)에 도입한다. 스코어 = 100, 워드렝쓰 (wordlength) = 12의 NBLAST 프로그램으로 BLAST 뉴클레오티드를 검색하여 본 발명의 MP 핵산 분자에 상동성인 뉴클레오티드 서열을 얻을 수 있다. 스코어 = 50, 워드렝쓰 = 3의 XBLAST 프로그램으로 BLAST 단백질을 검색하여 본 발명의 MP 단백질 분자에 상동성인 아미노산 서열을 얻을 수 있다. 문헌 [Altschul et al., (1997) Nucleic Acids Res. 25 (17):3389-3402]에 기재된 바와 같이 갭 BLAST를 이용하여 비교용 갭 정렬을 얻을 수 있다. 당업자라면, BLAST 및 갭 BLAST 프로그램을 이용할 때, 분석할 구체적인 서열에 대해 프로그램 (예를 들면, XBLAST 및 NBLAST)의 파라미터를 최적화하는 방법을 알 것이다.
서열 비교에 이용되는 수리적 알고리즘의 다른 예로는 문헌 [Meyers and Miller (1988) Comput. Appl. Biosci. 4:11-17]의 알고리즘이 있다. 이 알고리즘을 GCG 서열 정렬 소프트웨어 패키지의 일부인 ALIGN 프로그램 (버젼 2.0)에 도입한다. 아미노산 서열 비교를 위해 ALIGN 프로그램을 이용하는 경우, PAM 120 중량 잔기 표, 갭 길이 패널티 12, 및 갭 패널티 4를 사용할 수 있다. 추가의 서열 분석용 알고리즘이 당업계에 공지되어 있으며, 문헌 [Torelli and Robotti (1994) Comput. Appl. Biosci. 10:3-5]에 기재된 ADVANCE 및 ADAM., 및 문헌 [Pearson and Lipman (1988) P.N.A.S. 85:2444-8]에 기재된 FASTA를 포함한다.
또한, 2개의 아미노산 서열 사이의 상동성(%) 비교는 Blosum 62 매트릭스 또는 PAM250 매트릭스, 및 갭 중량 12, 10, 8, 6, 또는 4 및 길이 중량 2, 3, 또는 4를 사용하는 GCG 소프트웨어 패키지 (http://www.gcg.com에서 이용가능함) 중의 GAP 프로그램을 사용하여 수행할 수도 있다. 2개의 핵산 서열 사이의 상동성(%) 비교는 갭 중량 50 및 길이 중량 3 등의 표준 파라미터로 GCG 소프트웨어 패키지 중의 GAP 프로그램을 사용하여 수행할 수 있다.
당업계에 공지된 기술을 사용하여 본 발명의 유전자 서열과 젠뱅크의 유전자 서열을 비교 분석했다 (예를 들면, 문헌 [Bexevanis and Ouellette, eds. (1998) Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. John Wiley and Sons: New York] 참조). 본 발명의 유전자 서열과 젠뱅크의 유전자 서열을 3-단계 방법으로 비교했다. 제1단계에서, 본 발명의 서열 각각을 젠뱅크의 뉴클레오티드 서열에 대해 BLASTN 분석 (예를 들면, 국소 정렬 분석)하고, 추가의 분석을 위해 상위 500개의 히트 (hit)를 남겨 두었다. 그 다음에, 상기 500 히트에 대해 FASTA 검색 (예를 들면, 서열 중 한정된 영역을 정렬하는, 조합된 국소 및 전반적 정렬 분석)을 수행했다. 이어서, GCG 소프트웨어 패키지 중의 GAP 프로그램을 사용하여 (표준 파라미터 사용), 본 발명의 각 유전자 서열을 상위 3개의 FASTA 히트 각각에 전반적으로 정렬했다. 정확한 결과를 얻기 위해서, 젠뱅크에서 선별한 서열들의 길이를 당업계에 공지된 방법을 사용하여 해당 서열의 길이에 맞춰 조절했다. 상기 분석 결과를 표 4에 기재했다. 이렇게 얻은 데이타는 GAP (전반적) 분석 단독만을 수행하여 본 발명의 각 유전자를 젠뱅크의 참고 서열 각각과 비교하여 얻은 데이터와 동일하였으나, 상기 데이타베이스 - 광범위한 GAP (전반적) 분석과 비교할 때, 필요한 컴퓨터 이용 시간은 훨씬 감소했다. 본 발명의 서열 중 정렬이 되지 않은 것은 표 4에서 정렬 정보가 없는 컷오프 (cutoff) 값으로 나타냈다. 또한, 당업자라면, 표 4에서 GAP 정렬 상동성(%)을 "상동성(%) (GAP)"란 표제 하에 유럽식 숫자 포맷으로 열거하였으며, 여기서, ','는 소수점을 의미한다는 것을 이해할 것이다. 예를 들어, 이 단(段)에서 "40,345"란 값은 "40.345%"를 뜻한다.
실시예 12: DNA 미세배열체의 제작 및 시행
본 발명의 서열은 DNA 미세배열체 (microarray) (DNA 배열체 (array)의 고안, 방법, 및 용도는 당업계에 공지되어 있으며, 문헌 [Schena, M. et al. (1995) Science 270:467-470], 문헌 [Wodicka, L. et al. (1997) Nature Biotechnology 15:1359-1367], 문헌 [DeSaizieu, A. et al. (1998) Nature Biotechnology 16:45-48], 및 문헌 [DeRisi, J.L. et al. (1997) Science 278:680-686)] 등에 기재되어 있음)의 제작 및 적용에 추가로 이용될 수 있다.
DNA 미세배열체는 니트로셀룰로스, 나일론, 유리, 실리콘, 또는 기타 물질로 구성된 고체 또는 유연한 지지체이다. 핵산 분자들은 이 표면에 순차적인 방식으로 부착될 수 있다. 적절하게 표지한 후, 다른 핵산 또는 핵산 혼합물을 상기 고정된 핵산 분자에 혼성화시킬 수 있고, 상기 표지를 이용하여 한정된 영역에서 혼성화된 분자들의 개별적 신호 강도를 모니터링하고 측정할 수 있다. 이 방법을 이용하면, 적용한 핵산 샘플 또는 혼합물 중의 모든 핵산 또는 선택된 핵산의 상대량 또는 절대량을 동시에 정량할 수 있다. 그러므로, DNA 미세배열체는 대량의 (6800개 이상) 핵산 발현의 동시 분석을 가능케한다 (예를 들면, 문헌 [Schena, M. (1996) BioEssays 18 (5):427-431] 참조).
본 발명의 서열은 중합효소 연쇄반응 등의 핵산 증폭 반응으로 1종 이상의 코리네박테리움 글루타미쿰 유전자의 한정된 영역을 증폭시킬 수 있는 올리고뉴클레오티드 프라이머의 고안에 이용될 수 있다. 5' 또는 3' 올리고뉴클레오티드 프라이머 또는 적절한 링커 (linker)의 선택 및 고안으로 PCR 생성물을 상기 기재한 (또한, 예를 들어 문헌 [Schena, M. et al. (1995) Science 270:467-470]에도 기재되어 있음) 지지체 매질의 표면에 공유결합으로 부착할 수 있다.
또한, 핵산 미세배열체는 문헌 [Wodicka, L. et al. (1997) Nature Biotechnology 15:1359-1367]에 기재된 바와 같이, 계내 올리고뉴클레오티드 합성법으로 제작될 수도 있다. 사진석판법 (photolithographic method)에 따라, 정확히 한정된 영역의 매트릭스를 빛에 노출시킨다. 이로써, 빛에 불안정한 보호기가 활성화되어 뉴클레오티드 첨가가 일어나지만, 빛이 차폐된 영역에는 어떠한 변형도 일어나지 않는다. 그 후의 보호 및 광 활성화 사이클에 의해 한정된 위치에서 상이한 올리고뉴클레오티드가 합성된다. 본 발명의 유전자의 작은 한정 영역을 미세배열체 상에서의 고상 올리고뉴클레오티드 합성법으로 합성할 수 있다.
샘플 또는 뉴클레오티드 혼합물에 존재하는 본 발명의 핵산 분자는 미세배열체와 혼성화할 수 있다. 이러한 핵산 분자들은 표준 방법에 따라 표지될 수 있다. 간략하게, 동위원소 또는 형광 표지한 뉴클레오티드를 예를 들어, 역전사 동안 또는 DNA 합성 동안 혼입하여 핵산 분자 (예를 들면, mRNA 분자 또는 DNA 분자)를 표지한다. 표지된 핵산을 미세배열체에 혼성화하는 방법은 문헌 (예를 들어, 문헌 [Schena, M. et al. (1995) 상기 문헌], 문헌 [Wodicka, L. et al. (1997), 상기 문헌] 및 문헌 [DeSaizieu A. et al. (1998), 상기 문헌])에 기재되어 있다. 혼성화된 분자의 검출 및 정량화 방법은 혼입된 특정 표지에 따라 달라진다. 방사성 표지는 예를 들어, 문헌 [Schena, M. et al. (1995) 상기 문헌]에 기재된 방법으로 검출할 수 있고, 형광 표지는 예를 들어, 문헌 [Shalon et al. (1996) Genome Research 6:639-645]의 방법으로 검출할 수 있다.
상기 기재한 바와 같이, 본 발명의 서열을 DNA 미세배열체 기술에 적용하면 상이한 균주의 코리네박테리움 글루타미쿰 또는 다른 코리네박테리아를 비교 분석할 수 있다. 예를 들어, 개개의 전사체 프로필에 기초한 균주들 사이의 변이체 연구 및 병원성, 생산성 및 스트레스 내성 등과 같은 특정 및(또는) 원하는 균주 특성에 중요한 유전자의 확인은 핵산 배열법으로 용이해진다. 또한, 핵산 배열 기술을 사용하여, 발효 반응 과정 동안 본 발명의 유전자 발현 프로필을 비교할 수 있다.
실시예 13: 세포내 단백질 집단의 동력학(動力學) 분석 (프로테오믹스)
본 발명의 유전자, 조성물, 및 방법을 '프로테오믹스 (proteomics)'라 지칭되는, 단백질 집단의 상호작용 및 동력학 연구에 적용할 수 있다. 목적 단백질 집단에는 코리네박테리움 글루타미쿰의 전체 단백질 집단 (예를 들면, 다른 생물의 단백질 집단과의 비교시), 특정 환경 조건 또는 대사 조건 (예를 들면, 발효동안, 고온 또는 저온에서, 또는 높은 pH 또는 낮은 pH) 하에서 활성인 단백질 집단, 또는 성장 및 발생의 특정 시기 동안 활성인 단백질 집단 등이 있으나 이에 제한되는 것은 아니다.
겔 전기영동법 등의 각종 공지된 기술로 단백질 집단을 분석할 수 있다. 세포내 단백질은 용균 또는 추출 등으로 얻을 수 있고, 다양한 전기영동 기술을 사용하여 서로 분리해낼 수 있다. 소듐 도데실 술페이트 (sodium dodecyl sulfate) 폴리아크릴아미드 겔 전기영동 (SDS-PAGE)은 단백질들을 주로 이들의 분자량에 따라 분리한다. 등전점 포커싱 (isoelectric focusing) 폴리아크릴아미드 겔 전기영동법 (IEF-PAGE)은 단백질들을 그들의 등전점에 따라 분리한다 (아미노산 서열 뿐 아니라 그 단백질의 번역후 변형체도 분리해냄을 의미함). 또한, 더욱 바람직한 단백질 분석법은 2D-겔 전기영동법으로 공지된, IEF-PAGE 및 SDS-PAGE 둘다의 연속 병행법이다 (예를 들면, 문헌 [Hermann et al. (1998) Electrophoresis 19:3217-3221], 문헌 [Fountoulakis et al. (1998) Electrophoresis 19:1193-1202], 문헌 [Langen et al. (1997) Electrophoresis 18:1184-1192], 문헌 [Antelmann et al. (1997) Electrophoresis 18:1451-1463]에 기재되어 있음). 또한, 모세관 겔 전기영동법 등과 같이 당업계에 공지된 다른 분리 기술을 이용하여 단백질을 분리할 수도 있다.
이러한 방법으로 분리된 단백질을 염색 또는 표지 등의 표준 기술로 가시화할 수 있다. 적당한 염색약은 당업계에 공지되어 있으며, 쿠마시 브릴리안트 블루, 실버 염색약, 또는 시프로 루비 (Sypro Ruby) (Molecular Probes 제품) 등과 같은 형광 염료 등이 있다. 방사성 표지된 아미노산 또는 기타의 단백질 전구체 (예를 들면, 35S-메티오닌, 35S-시스테인, 14C-표지된 아미노산, 15N-아미노산, 15NO3 또는 15NH4 + 또는 13C-표지된 아미노산)를 코리네박테리움 글루타미쿰 배지에 포함시키면, 세포로부터의 단백질을 분리해내기 전에 이들을 표지할 수 있다. 유사하게, 형광 표지를 이용할 수 있다. 이렇게 표지된 단백질을 상기 기재한 기술에 따라 추출, 단리 및 분리할 수 있다.
상기 기술로 가시화된 단백질은 사용된 염료 또는 표지의 양을 측정하여 더욱 분석될 수 있다. 주어진 단백질의 양은 광학적 방법 등을 이용하여 정량적으로 측정할 수 있고, 동일 겔 또는 다른 겔 중의 다른 단백질 양과 비교할 수 있다. 광학적 비교법, 분광법, 이미지 스캐닝 및 겔 분석, 또는 사진용 필름 및 스크린의 사용 등을 통해 겔 상의 단백질을 비교할 수 있다. 상기 기술들은 당업계에 공지되어 있다.
임의의 주어진 단백질이 무엇인지 결정하기 위해, 직접적인 서열분석법 또는 다른 표준 기술을 이용할 수 있다. 예를 들면, N- 및(또는) C-말단 아미노산 서열분석법 (예를 들면, 에드만 분해법) 및 질량 분광분석법 (특히, MALDI 또는 ESI 기술 (예를 들면, 문헌 [Langen et al. (1997) Electrophoresis 18:1184-1192] 참조))을 이용할 수 있다. 이러한 기술들을 사용하여, 본원에서 제공되는 단백질 서열을 코리네박테리움 글루타미쿰 단백질 확인에 사용할 수 있다.
상기 방법으로 얻은 정보를 사용하여 각종 생물학적 조건 (예를 들면, 상이한 생물, 발효 시점, 배지 조건, 또는 서로간의 상이한 환경 (biotope))으로부터의 상이한 샘플들 사이에서 단백질 존재 여부, 활성 또는 변형의 양상들을 비교할 수 있다. 상기 실험 단독으로 또는 다른 기술들과 병행하여 얻어진 데이타는 주어진 상태 (예를 들면, 대사 상태)에서 각종 생물의 반응 비교, 정밀 화학물질을 생성하는 균주의 생산성 증가, 또는 정밀 화학물질의 생성 효율 증가 등 여러가지 목적을 위해 적용할 수 있다.
등가법
당업자라면, 일상적인 실험 방법 뿐 아니라 본원에 기재한 본 발명의 특정 실시양태와 등가인 많은 실험 방법들을 알고 있거나, 알아낼 수 있을 것이다. 이러한 동등한 방법들은 하기의 청구항에 포함될 것이다.
본 발명은 다양한 용도를 갖는 신규 박테리아 핵산 분자를 제공한다. 상기 용도로는 코리네박테리움 글루타미쿰의 게놈을 맵핑하기 위한 기준점 및 형질전환용 마커로서 정밀 화학물질의 생산에 사용될 수 있는 미생물의 확인, 코리네박테리움 글루타미쿰 또는 관련 박테리아에서의 정밀 화학물질의 생산 조절, 및 코리네박테리움 글루타미쿰 또는 관련 박테리아의 타이핑 또는 확인 등이 있다. 이들 신규 핵산 분자는 본원에서 대사 경로 (MP) 단백질로 언급되는 단백질을 코딩한다.
SEQUENCE LISTING <110> BASF Aktiengesellschaft <120> CORYNEBACTERIUM GLUTAMICUM GENES ENCODING METABOLIC PATHWAY PROTEINS <130> BGI-121CPPC <140> PCT/00IB/00923 <141> 2000-06-23 <150> US 60/141,031 <151> 1999-06-25 <150> US 60/142,101 <151> 1999-07-02 <150> US 60/148,613 <151> 1999-08-12 <150> US 60/187,970 <151> 2000-03-09 <150> DE 19930476.9 <151> 1999-07-01 <150> DE 19931415.2 <151> 1999-07-08 <150> DE 19931418.7 <151> 1999-07-08 <150> DE 19931419.5 <151> 1999-07-08 <150> DE 19931420.9 <151> 1999-07-08 <150> DE 19931424.1 <151> 1999-07-08 <150> DE 19931428.4 <151> 1999-07-08 <150> DE 19931434.9 <151> 1999-07-08 <150> DE 19931435.7 <151> 1999-07-08 <150> DE 19931443.8 <151> 1999-07-08 <150> DE 19931453.5 <151> 1999-07-08 <150> DE 19931457.8 <151> 1999-07-08 <150> DE 19931465.9 <151> 1999-07-08 <150> DE 19931478.0 <151> 1999-07-08 <150> DE 19931510.8 <151> 1999-07-08 <150> DE 19931541.8 <151> 1999-07-08 <150> DE 19931573.6 <151> 1999-07-08 <150> DE 19931592.2 <151> 1999-07-08 <150> DE 19931632.5 <151> 1999-07-08 <150> DE 19931634.1 <151> 1999-07-08 <150> DE 19931636.8 <151> 1999-07-08 <150> DE 19932125.6 <151> 1999-07-09 <150> DE 19932126.4 <151> 1999-07-09 <150> DE 19932130.2 <151> 1999-07-09 <150> DE 19932186.8 <151> 1999-07-09 <150> DE 19932206.6 <151> 1999-07-09 <150> DE 19932227.9 <151> 1999-07-09 <150> DE 19932228.7 <151> 1999-07-09 <150> DE 19932229.5 <151> 1999-07-09 <150> DE 19932230.9 <151> 1999-07-09 <150> DE 19932922.2 <151> 1999-07-14 <150> DE 19932926.5 <151> 1999-07-14 <150> DE 19932928.1 <151> 1999-07-14 <150> DE 19933004.2 <151> 1999-07-14 <150> DE 19933005.0 <151> 1999-07-14 <150> DE 19933006.9 <151> 1999-07-14 <150> DE 19940764.9 <151> 1999-08-27 <150> DE 19940765.7 <151> 1999-08-27 <150> DE 19940766.5 <151> 1999-08-27 <150> DE 19940832.7 <151> 1999-08-27 <150> DE 19941378.9 <151> 1999-08-31 <150> DE 19941379.7 <151> 1999-08-31 <150> DE 19941380.0 <151> 1999-08-31 <150> DE 19941394.0 <151> 1999-08-31 <150> DE 19941396.7 <151> 1999-08-31 <150> DE 19942076.9 <151> 1999-09-03 <150> DE 19942077.7 <151> 1999-09-03 <150> DE 19942079.3 <151> 1999-09-03 <150> DE 19942086.6 <151> 1999-09-03 <150> DE 19942087.4 <151> 1999-09-03 <150> DE 19942088.2 <151> 1999-09-03 <150> DE 19942095.5 <151> 1999-09-03 <150> DE 19942124.2 <151> 1999-09-03 <150> DE 19942129.3 <151> 1999-09-03 <160> 1158 <210> 1 <211> 948 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(925) <223> RXA02229 <400> 1 gctggttcaa cagagaccac cgcgtgtcct gggtcgacgc ctctggcgat cccaccgcac 60 aagccttgga gattttgggt ctacaatagc gagggtgaat ttg acc atc ccc ttt 115 Leu Thr Ile Pro Phe 1 5 gcc aaa ggc cac gcc acc gaa aac gac ttc atc atc atc ccc gat gag 163 Ala Lys Gly His Ala Thr Glu Asn Asp Phe Ile Ile Ile Pro Asp Glu 10 15 20 gat gcg cgc cta gat tta act cca gaa atg gtg gtc acg ctg tgt gac 211 Asp Ala Arg Leu Asp Leu Thr Pro Glu Met Val Val Thr Leu Cys Asp 25 30 35 cgc cgc gcc ggg atc ggt gct gat ggt atc ctc cgc gtg gtt aaa gct 259 Arg Arg Ala Gly Ile Gly Ala Asp Gly Ile Leu Arg Val Val Lys Ala 40 45 50 gca gac gta gaa ggc tcc acg gtc gac cca tcg ctg tgg ttc atg gat 307 Ala Asp Val Glu Gly Ser Thr Val Asp Pro Ser Leu Trp Phe Met Asp 55 60 65 tac cgc aac gcc gat gga tct ttg gct gaa atg tgc ggc aat ggt gtg 355 Tyr Arg Asn Ala Asp Gly Ser Leu Ala Glu Met Cys Gly Asn Gly Val 70 75 80 85 cgc ctg ttc gcg cac tgg ctg tac tcc cgc ggt ctt gtt gat aat acg 403 Arg Leu Phe Ala His Trp Leu Tyr Ser Arg Gly Leu Val Asp Asn Thr 90 95 100 agc ttt gat atc ggt acc cgc gcc ggt gtc cgc cac gtt gat att ttg 451 Ser Phe Asp Ile Gly Thr Arg Ala Gly Val Arg His Val Asp Ile Leu 105 110 115 cag gca gat caa cat tct gcg cag gtc cgc gtt gat atg ggc atc cct 499 Gln Ala Asp Gln His Ser Ala Gln Val Arg Val Asp Met Gly Ile Pro 120 125 130 gac gtc acg gga tta tcc acc tgc gac atc aac ggc caa gta ttc gct 547 Asp Val Thr Gly Leu Ser Thr Cys Asp Ile Asn Gly Gln Val Phe Ala 135 140 145 ggc ctt ggc gtt gat atg ggt aac cca cac cta gcg tgc gtt gtg ccg 595 Gly Leu Gly Val Asp Met Gly Asn Pro His Leu Ala Cys Val Val Pro 150 155 160 165 ggc tta agt gcg tcg gct ctt gcc gat atg gaa ctg cgc gca cct acg 643 Gly Leu Ser Ala Ser Ala Leu Ala Asp Met Glu Leu Arg Ala Pro Thr 170 175 180 ttt gat cag gaa ttc ttc ccc cac ggt gtg aac gta gaa atc gtc aca 691 Phe Asp Gln Glu Phe Phe Pro His Gly Val Asn Val Glu Ile Val Thr 185 190 195 gaa tta gaa gat gac gca gta tcg atg cgc gtg tgg gaa cgc gga gtg 739 Glu Leu Glu Asp Asp Ala Val Ser Met Arg Val Trp Glu Arg Gly Val 200 205 210 ggc gaa acc cgc tcc tgt ggc acg gga acc gtt gct gca gcg tgt gct 787 Gly Glu Thr Arg Ser Cys Gly Thr Gly Thr Val Ala Ala Ala Cys Ala 215 220 225 gct tta gct gat gct gga ttg gga gaa ggc aca gct aaa gtg tgc gtt 835 Ala Leu Ala Asp Ala Gly Leu Gly Glu Gly Thr Ala Lys Val Cys Val 230 235 240 245 cca cgt ggg gaa gta gaa gtc cag atc ttt gac gac ggc tcc aca ctc 883 Pro Arg Gly Glu Val Glu Val Gln Ile Phe Asp Asp Gly Ser Thr Leu 250 255 260 acc ggc cca agc gcc atc atc gca ctc ggt gag gtg cag atc 925 Thr Gly Pro Ser Ala Ile Ile Ala Leu Gly Glu Val Gln Ile 265 270 275 taagattcgc gattgtagtt cgg 948 <210> 2 <211> 275 <212> PRT <213> Corynebacterium glutamicum <400> 2 Leu Thr Ile Pro Phe Ala Lys Gly His Ala Thr Glu Asn Asp Phe Ile 1 5 10 15 Ile Ile Pro Asp Glu Asp Ala Arg Leu Asp Leu Thr Pro Glu Met Val 20 25 30 Val Thr Leu Cys Asp Arg Arg Ala Gly Ile Gly Ala Asp Gly Ile Leu 35 40 45 Arg Val Val Lys Ala Ala Asp Val Glu Gly Ser Thr Val Asp Pro Ser 50 55 60 Leu Trp Phe Met Asp Tyr Arg Asn Ala Asp Gly Ser Leu Ala Glu Met 65 70 75 80 Cys Gly Asn Gly Val Arg Leu Phe Ala His Trp Leu Tyr Ser Arg Gly 85 90 95 Leu Val Asp Asn Thr Ser Phe Asp Ile Gly Thr Arg Ala Gly Val Arg 100 105 110 His Val Asp Ile Leu Gln Ala Asp Gln His Ser Ala Gln Val Arg Val 115 120 125 Asp Met Gly Ile Pro Asp Val Thr Gly Leu Ser Thr Cys Asp Ile Asn 130 135 140 Gly Gln Val Phe Ala Gly Leu Gly Val Asp Met Gly Asn Pro His Leu 145 150 155 160 Ala Cys Val Val Pro Gly Leu Ser Ala Ser Ala Leu Ala Asp Met Glu 165 170 175 Leu Arg Ala Pro Thr Phe Asp Gln Glu Phe Phe Pro His Gly Val Asn 180 185 190 Val Glu Ile Val Thr Glu Leu Glu Asp Asp Ala Val Ser Met Arg Val 195 200 205 Trp Glu Arg Gly Val Gly Glu Thr Arg Ser Cys Gly Thr Gly Thr Val 210 215 220 Ala Ala Ala Cys Ala Ala Leu Ala Asp Ala Gly Leu Gly Glu Gly Thr 225 230 235 240 Ala Lys Val Cys Val Pro Arg Gly Glu Val Glu Val Gln Ile Phe Asp 245 250 255 Asp Gly Ser Thr Leu Thr Gly Pro Ser Ala Ile Ile Ala Leu Gly Glu 260 265 270 Val Gln Ile 275 <210> 3 <211> 1491 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1468) <223> RXS02970 <400> 3 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc gtg tgg ccg atg atc tcc ggc aac cga ttc cac 1363 Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser Gly Asn Arg Phe His 410 415 420 atc gcg ccg ccg ctg acc acc act gat gac gaa ttg gta gca ctg ctg 1411 Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu Leu Val Ala Leu Leu 425 430 435 gac gcg gtg gaa gct gca gcc caa gct gtc gag ctg acc ttc gct ggg 1459 Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu Leu Thr Phe Ala Gly 440 445 450 gcg ttg ttc taagttttct agataacaag gcc 1491 Ala Leu Phe 455 <210> 4 <211> 456 <212> PRT <213> Corynebacterium glutamicum <400> 4 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser 405 410 415 Gly Asn Arg Phe His Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu 420 425 430 Leu Val Ala Leu Leu Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu 435 440 445 Leu Thr Phe Ala Gly Ala Leu Phe 450 455 <210> 5 <211> 1330 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1330) <223> FRXA01009 <400> 5 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc 1330 Phe Lys Glu Arg Gly 410 <210> 6 <211> 410 <212> PRT <213> Corynebacterium glutamicum <400> 6 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly 405 410 <210> 7 <211> 792 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(769) <223> RXC02390 <400> 7 gctggtggtg ctgacccata cgctggaact ccaactgctg ttgataccgc caagatgttt 60 ggccgcgagg atctcgtagc tcgcttcgag tcataggccg gtg gag tgg acc gct 115 Val Glu Trp Thr Ala 1 5 ttt ggc acc ctg att ctg ctc aat ttg gtg ggc agt tta tcc ccg ggg 163 Phe Gly Thr Leu Ile Leu Leu Asn Leu Val Gly Ser Leu Ser Pro Gly 10 15 20 cct gat acc ttt ttc ctc ctc cgc tta gcc acc cgc tcc aga gcg cac 211 Pro Asp Thr Phe Phe Leu Leu Arg Leu Ala Thr Arg Ser Arg Ala His 25 30 35 gcg atc gct ggc gtc gcc ggc atc gtc acc gga ctc acg gtg tgg gtg 259 Ala Ile Ala Gly Val Ala Gly Ile Val Thr Gly Leu Thr Val Trp Val 40 45 50 acg ctg acg gtc gtg gga gca gcg gcg ctg ctc acc act tat ccg tcg 307 Thr Leu Thr Val Val Gly Ala Ala Ala Leu Leu Thr Thr Tyr Pro Ser 55 60 65 att ctc gga atc atc cag ctc gtc ggc ggc acg tac cta agc ttc att 355 Ile Leu Gly Ile Ile Gln Leu Val Gly Gly Thr Tyr Leu Ser Phe Ile 70 75 80 85 ggg tac aag ttg ctg cgc tcg gcg tcg aga gag ctt atc gac gcc cgc 403 Gly Tyr Lys Leu Leu Arg Ser Ala Ser Arg Glu Leu Ile Asp Ala Arg 90 95 100 cag ttc cgt ttc aac gcc gat gcc cga cct atc ccg gat gcg gta gaa 451 Gln Phe Arg Phe Asn Ala Asp Ala Arg Pro Ile Pro Asp Ala Val Glu 105 110 115 gca ctg gga acc cgc act cag gta tat cga caa ggt ttg gcc acc aac 499 Ala Leu Gly Thr Arg Thr Gln Val Tyr Arg Gln Gly Leu Ala Thr Asn 120 125 130 ctg tca aac cct aaa gtt gtc atg tac ttc gcg gca att ctg gct ccg 547 Leu Ser Asn Pro Lys Val Val Met Tyr Phe Ala Ala Ile Leu Ala Pro 135 140 145 ttg atg cca gcg cac cca tca ccg gtg ctg gcg ttc tct atc atc gtg 595 Leu Met Pro Ala His Pro Ser Pro Val Leu Ala Phe Ser Ile Ile Val 150 155 160 165 gcg att tta gtg cag acc ttt gtt acc ttc tct gct gtg tgc ctc att 643 Ala Ile Leu Val Gln Thr Phe Val Thr Phe Ser Ala Val Cys Leu Ile 170 175 180 gtc tct acg gag cgt gtg cgc aaa gca atg ctg cgt gca ggt ccc tgg 691 Val Ser Thr Glu Arg Val Arg Lys Ala Met Leu Arg Ala Gly Pro Trp 185 190 195 ttt gac ctg ctt gct ggc gtt gtc ttc ctc gtt gtg ggt gtg act ctg 739 Phe Asp Leu Leu Ala Gly Val Val Phe Leu Val Val Gly Val Thr Leu 200 205 210 ctg tat gaa ggc ctg acc ggt tta ctc ggg taaaggcata aaaaatggct 789 Leu Tyr Glu Gly Leu Thr Gly Leu Leu Gly 215 220 tcc 792 <210> 8 <211> 223 <212> PRT <213> Corynebacterium glutamicum <400> 8 Val Glu Trp Thr Ala Phe Gly Thr Leu Ile Leu Leu Asn Leu Val Gly 1 5 10 15 Ser Leu Ser Pro Gly Pro Asp Thr Phe Phe Leu Leu Arg Leu Ala Thr 20 25 30 Arg Ser Arg Ala His Ala Ile Ala Gly Val Ala Gly Ile Val Thr Gly 35 40 45 Leu Thr Val Trp Val Thr Leu Thr Val Val Gly Ala Ala Ala Leu Leu 50 55 60 Thr Thr Tyr Pro Ser Ile Leu Gly Ile Ile Gln Leu Val Gly Gly Thr 65 70 75 80 Tyr Leu Ser Phe Ile Gly Tyr Lys Leu Leu Arg Ser Ala Ser Arg Glu 85 90 95 Leu Ile Asp Ala Arg Gln Phe Arg Phe Asn Ala Asp Ala Arg Pro Ile 100 105 110 Pro Asp Ala Val Glu Ala Leu Gly Thr Arg Thr Gln Val Tyr Arg Gln 115 120 125 Gly Leu Ala Thr Asn Leu Ser Asn Pro Lys Val Val Met Tyr Phe Ala 130 135 140 Ala Ile Leu Ala Pro Leu Met Pro Ala His Pro Ser Pro Val Leu Ala 145 150 155 160 Phe Ser Ile Ile Val Ala Ile Leu Val Gln Thr Phe Val Thr Phe Ser 165 170 175 Ala Val Cys Leu Ile Val Ser Thr Glu Arg Val Arg Lys Ala Met Leu 180 185 190 Arg Ala Gly Pro Trp Phe Asp Leu Leu Ala Gly Val Val Phe Leu Val 195 200 205 Val Gly Val Thr Leu Leu Tyr Glu Gly Leu Thr Gly Leu Leu Gly 210 215 220 <210> 9 <211> 897 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(874) <223> RXC01796 <400> 9 atgtaactcg atcaggtgga aatgcccgca aaagtggcgg cggtggccga gggatggccg 60 ttggtgcggc atcggtggcc tgctactagt cgggctcttc ttg ctc ctt ggc ggt 115 Leu Leu Leu Gly Gly 1 5 aac cct gcc gag atc gac cag gtt tta ggt ggc gat caa acc cag atc 163 Asn Pro Ala Glu Ile Asp Gln Val Leu Gly Gly Asp Gln Thr Gln Ile 10 15 20 gag tct gga gag tcc acc gga gcc ggc gac ttt gat cac tgc caa acc 211 Glu Ser Gly Glu Ser Thr Gly Ala Gly Asp Phe Asp His Cys Gln Thr 25 30 35 ggc gca gat gcc aac gcc agt gat gat tgt cgc ctt tac tac acc tca 259 Gly Ala Asp Ala Asn Ala Ser Asp Asp Cys Arg Leu Tyr Tyr Thr Ser 40 45 50 ttc tcc gtc aat gaa atg tgg cag act ttg ctt cca gct cag gct ggt 307 Phe Ser Val Asn Glu Met Trp Gln Thr Leu Leu Pro Ala Gln Ala Gly 55 60 65 atc gaa tac acc gag ccg aca ttg act ctt ttc aaa aac tcc acc caa 355 Ile Glu Tyr Thr Glu Pro Thr Leu Thr Leu Phe Lys Asn Ser Thr Gln 70 75 80 85 acc ggc tgc ggt ttc gct tct gcg tcc act ggg ccg ttt tac tgt ccg 403 Thr Gly Cys Gly Phe Ala Ser Ala Ser Thr Gly Pro Phe Tyr Cys Pro 90 95 100 tca gac caa gat gct tat ttt gac ttg act ttc ttc gat cag atg cgt 451 Ser Asp Gln Asp Ala Tyr Phe Asp Leu Thr Phe Phe Asp Gln Met Arg 105 110 115 cag ttc ggt gca gaa aac gcc ccg ctt gcc cag atg tac atc gtg gcg 499 Gln Phe Gly Ala Glu Asn Ala Pro Leu Ala Gln Met Tyr Ile Val Ala 120 125 130 cac gag tac ggc cac cac gtc caa aac ctc gag ggc aca ctc gga ctg 547 His Glu Tyr Gly His His Val Gln Asn Leu Glu Gly Thr Leu Gly Leu 135 140 145 tcc aat tac aac gat ccg ggc gct gat tcc aac gcc gtc aag atc gag 595 Ser Asn Tyr Asn Asp Pro Gly Ala Asp Ser Asn Ala Val Lys Ile Glu 150 155 160 165 ttg cag gcc gat tgc tac gca ggc att tgg gct aat cac tcc agc gaa 643 Leu Gln Ala Asp Cys Tyr Ala Gly Ile Trp Ala Asn His Ser Ser Glu 170 175 180 ggc ccg gat ccg cta ctc caa ccc atc acc gaa tct gag cta gat tcc 691 Gly Pro Asp Pro Leu Leu Gln Pro Ile Thr Glu Ser Glu Leu Asp Ser 185 190 195 gct ctc ctt gct gca agc gcc gtg ggc gac gac aat atc cag caa cga 739 Ala Leu Leu Ala Ala Ser Ala Val Gly Asp Asp Asn Ile Gln Gln Arg 200 205 210 tcc ggt ggc gat gtc aat cct gaa agc tgg act cac ggc tca tcg cag 787 Ser Gly Gly Asp Val Asn Pro Glu Ser Trp Thr His Gly Ser Ser Gln 215 220 225 cag cgc aaa gac gcg ttc ctc gcc ggc tac aac acc ggc cag atg agc 835 Gln Arg Lys Asp Ala Phe Leu Ala Gly Tyr Asn Thr Gly Gln Met Ser 230 235 240 245 gcc tgc gac ttc ctc ggc cgg ggc gtc tac aac gac gct taaagcattg 884 Ala Cys Asp Phe Leu Gly Arg Gly Val Tyr Asn Asp Ala 250 255 cttttcgacg tct 897 <210> 10 <211> 258 <212> PRT <213> Corynebacterium glutamicum <400> 10 Leu Leu Leu Gly Gly Asn Pro Ala Glu Ile Asp Gln Val Leu Gly Gly 1 5 10 15 Asp Gln Thr Gln Ile Glu Ser Gly Glu Ser Thr Gly Ala Gly Asp Phe 20 25 30 Asp His Cys Gln Thr Gly Ala Asp Ala Asn Ala Ser Asp Asp Cys Arg 35 40 45 Leu Tyr Tyr Thr Ser Phe Ser Val Asn Glu Met Trp Gln Thr Leu Leu 50 55 60 Pro Ala Gln Ala Gly Ile Glu Tyr Thr Glu Pro Thr Leu Thr Leu Phe 65 70 75 80 Lys Asn Ser Thr Gln Thr Gly Cys Gly Phe Ala Ser Ala Ser Thr Gly 85 90 95 Pro Phe Tyr Cys Pro Ser Asp Gln Asp Ala Tyr Phe Asp Leu Thr Phe 100 105 110 Phe Asp Gln Met Arg Gln Phe Gly Ala Glu Asn Ala Pro Leu Ala Gln 115 120 125 Met Tyr Ile Val Ala His Glu Tyr Gly His His Val Gln Asn Leu Glu 130 135 140 Gly Thr Leu Gly Leu Ser Asn Tyr Asn Asp Pro Gly Ala Asp Ser Asn 145 150 155 160 Ala Val Lys Ile Glu Leu Gln Ala Asp Cys Tyr Ala Gly Ile Trp Ala 165 170 175 Asn His Ser Ser Glu Gly Pro Asp Pro Leu Leu Gln Pro Ile Thr Glu 180 185 190 Ser Glu Leu Asp Ser Ala Leu Leu Ala Ala Ser Ala Val Gly Asp Asp 195 200 205 Asn Ile Gln Gln Arg Ser Gly Gly Asp Val Asn Pro Glu Ser Trp Thr 210 215 220 His Gly Ser Ser Gln Gln Arg Lys Asp Ala Phe Leu Ala Gly Tyr Asn 225 230 235 240 Thr Gly Gln Met Ser Ala Cys Asp Phe Leu Gly Arg Gly Val Tyr Asn 245 250 255 Asp Ala <210> 11 <211> 771 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(748) <223> RXC01207 <400> 11 cttcatgatc tcaccggcag agcgcgtttt gttacagcgc gtaaactgtg actttgaaaa 60 atttttgaac aatccgtaca ccaacttcag gagaaaaaca gtg agc aga atc tat 115 Val Ser Arg Ile Tyr 1 5 gac tgt gcc gac caa gac tcc cgt gca gca ggc cta aag gcg gct gtc 163 Asp Cys Ala Asp Gln Asp Ser Arg Ala Ala Gly Leu Lys Ala Ala Val 10 15 20 gat gca gtc aaa gcc ggt cag ctc gtt gtc ctt ccc acg gat acc ctt 211 Asp Ala Val Lys Ala Gly Gln Leu Val Val Leu Pro Thr Asp Thr Leu 25 30 35 tat gga ctc ggc tgc gac gct ttc aac aac gag gca gta gcc aac ctt 259 Tyr Gly Leu Gly Cys Asp Ala Phe Asn Asn Glu Ala Val Ala Asn Leu 40 45 50 ctg gcc acc aaa cac cgt ggc ccc gat atg ccc gtt cca gtg ctc gtc 307 Leu Ala Thr Lys His Arg Gly Pro Asp Met Pro Val Pro Val Leu Val 55 60 65 ggc agc tgg gac acc att caa gga ctt gtg cac tcc tat tct gcg cag 355 Gly Ser Trp Asp Thr Ile Gln Gly Leu Val His Ser Tyr Ser Ala Gln 70 75 80 85 gca aaa gcg ctt gtg gag gcg ttc tgg cct ggt gga ctg tcc atc atc 403 Ala Lys Ala Leu Val Glu Ala Phe Trp Pro Gly Gly Leu Ser Ile Ile 90 95 100 gtt ccg cag gca cca agc ctt ccg tgg aac ctt ggc gat acc cgt ggc 451 Val Pro Gln Ala Pro Ser Leu Pro Trp Asn Leu Gly Asp Thr Arg Gly 105 110 115 acc gta atg ctg cgc atg cca ctg cac cca gtt gcc att gaa ttg ctg 499 Thr Val Met Leu Arg Met Pro Leu His Pro Val Ala Ile Glu Leu Leu 120 125 130 cgc caa acc gga cca atg gct gtc tcc tcc gcc aac atc tcc gga cat 547 Arg Gln Thr Gly Pro Met Ala Val Ser Ser Ala Asn Ile Ser Gly His 135 140 145 act cct cca acc acc gtg ctg gag gct cgt cag cag ctc aac caa aat 595 Thr Pro Pro Thr Thr Val Leu Glu Ala Arg Gln Gln Leu Asn Gln Asn 150 155 160 165 gtc gct gtc tac ctc gat ggt ggc gaa tgc gcg ctg gcc acc cct tca 643 Val Ala Val Tyr Leu Asp Gly Gly Glu Cys Ala Leu Ala Thr Pro Ser 170 175 180 acc atc gtg gat att tca ggc ccc gca cca aag att ttg cgt gag ggt 691 Thr Ile Val Asp Ile Ser Gly Pro Ala Pro Lys Ile Leu Arg Glu Gly 185 190 195 gcc atc agc gca gaa cgc gtt ggc gaa gta ctt gga gtg tcg gca gaa 739 Ala Ile Ser Ala Glu Arg Val Gly Glu Val Leu Gly Val Ser Ala Glu 200 205 210 agc ctg cgc taaatgggag tcggtttcgc ggg 771 Ser Leu Arg 215 <210> 12 <211> 216 <212> PRT <213> Corynebacterium glutamicum <400> 12 Val Ser Arg Ile Tyr Asp Cys Ala Asp Gln Asp Ser Arg Ala Ala Gly 1 5 10 15 Leu Lys Ala Ala Val Asp Ala Val Lys Ala Gly Gln Leu Val Val Leu 20 25 30 Pro Thr Asp Thr Leu Tyr Gly Leu Gly Cys Asp Ala Phe Asn Asn Glu 35 40 45 Ala Val Ala Asn Leu Leu Ala Thr Lys His Arg Gly Pro Asp Met Pro 50 55 60 Val Pro Val Leu Val Gly Ser Trp Asp Thr Ile Gln Gly Leu Val His 65 70 75 80 Ser Tyr Ser Ala Gln Ala Lys Ala Leu Val Glu Ala Phe Trp Pro Gly 85 90 95 Gly Leu Ser Ile Ile Val Pro Gln Ala Pro Ser Leu Pro Trp Asn Leu 100 105 110 Gly Asp Thr Arg Gly Thr Val Met Leu Arg Met Pro Leu His Pro Val 115 120 125 Ala Ile Glu Leu Leu Arg Gln Thr Gly Pro Met Ala Val Ser Ser Ala 130 135 140 Asn Ile Ser Gly His Thr Pro Pro Thr Thr Val Leu Glu Ala Arg Gln 145 150 155 160 Gln Leu Asn Gln Asn Val Ala Val Tyr Leu Asp Gly Gly Glu Cys Ala 165 170 175 Leu Ala Thr Pro Ser Thr Ile Val Asp Ile Ser Gly Pro Ala Pro Lys 180 185 190 Ile Leu Arg Glu Gly Ala Ile Ser Ala Glu Arg Val Gly Glu Val Leu 195 200 205 Gly Val Ser Ala Glu Ser Leu Arg 210 215 <210> 13 <211> 1026 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1003) <223> RXC00657 <400> 13 gtgcggatcg ggtatccgcg ctacacttag aggtgttaga gatcatgagt ttccacgaac 60 tgtaacgcag gattcaccaa tcaatgaaag gtcgaccgac atg agc act gaa gac 115 Met Ser Thr Glu Asp 1 5 att gtc gtc gta gca gta gat ggc tcg gac gcc tca aaa caa gct gtt 163 Ile Val Val Val Ala Val Asp Gly Ser Asp Ala Ser Lys Gln Ala Val 10 15 20 cgg tgg gct gca aat acc gcc aac aaa cgt ggc att cca ctt cgc ttg 211 Arg Trp Ala Ala Asn Thr Ala Asn Lys Arg Gly Ile Pro Leu Arg Leu 25 30 35 gct tcc agc tac acc atg cct cag ttc ctc tac gca gag gga atg gtt 259 Ala Ser Ser Tyr Thr Met Pro Gln Phe Leu Tyr Ala Glu Gly Met Val 40 45 50 cca cca caa gag ctt ttc gat gac ctc cag gcc gaa gcc ctg gaa aag 307 Pro Pro Gln Glu Leu Phe Asp Asp Leu Gln Ala Glu Ala Leu Glu Lys 55 60 65 att aac gaa gcc cgt gac atc gcc cat gag gta gcg cca gaa atc aag 355 Ile Asn Glu Ala Arg Asp Ile Ala His Glu Val Ala Pro Glu Ile Lys 70 75 80 85 atc ggg cac acc atc gct gaa ggc agt ccc atc gac atg ctg ttg gaa 403 Ile Gly His Thr Ile Ala Glu Gly Ser Pro Ile Asp Met Leu Leu Glu 90 95 100 atg tct ccc gat gcc aca atg atc gtc atg ggt tcc cgc gga ctc ggc 451 Met Ser Pro Asp Ala Thr Met Ile Val Met Gly Ser Arg Gly Leu Gly 105 110 115 gga ctc tcc gga atg gtc atg ggc tcc gtc tcc ggt gca gtg gtc agc 499 Gly Leu Ser Gly Met Val Met Gly Ser Val Ser Gly Ala Val Val Ser 120 125 130 cac gca aag tgt cca gtc gtt gtt gtc cgt gaa gac agc gca gtc aac 547 His Ala Lys Cys Pro Val Val Val Val Arg Glu Asp Ser Ala Val Asn 135 140 145 gaa gac agc aag tac ggc cca gtc gtc gtc ggt gtg gat ggc tcc gaa 595 Glu Asp Ser Lys Tyr Gly Pro Val Val Val Gly Val Asp Gly Ser Glu 150 155 160 165 gtc tcc caa cag gca acc gaa tac gca ttt gcg gaa gct gaa gct cgt 643 Val Ser Gln Gln Ala Thr Glu Tyr Ala Phe Ala Glu Ala Glu Ala Arg 170 175 180 ggc gcc gaa ctc gtt gca gtt cac acc tgg atg gac atg cag gta cag 691 Gly Ala Glu Leu Val Ala Val His Thr Trp Met Asp Met Gln Val Gln 185 190 195 gca tca ctt gca ggt ctt gca gct gct caa cag cag tgg gat gaa gtg 739 Ala Ser Leu Ala Gly Leu Ala Ala Ala Gln Gln Gln Trp Asp Glu Val 200 205 210 gaa cgt cag caa acc gac atg ctg atc gaa cgc ctc gca cca ctg gtg 787 Glu Arg Gln Gln Thr Asp Met Leu Ile Glu Arg Leu Ala Pro Leu Val 215 220 225 gaa aag tac cca agt gta acc gtc aag aag atc atc acc cgt gac cgc 835 Glu Lys Tyr Pro Ser Val Thr Val Lys Lys Ile Ile Thr Arg Asp Arg 230 235 240 245 cca gtt cgc gca ctt gca gaa gca tct gaa aac gcg cag ctc cta gtc 883 Pro Val Arg Ala Leu Ala Glu Ala Ser Glu Asn Ala Gln Leu Leu Val 250 255 260 gtt ggt tcc cat ggt cgt ggc gga ttt aag ggc atg ctc ctt ggc tcc 931 Val Gly Ser His Gly Arg Gly Gly Phe Lys Gly Met Leu Leu Gly Ser 265 270 275 acc tcc cgc gca ctg ctg caa tcc gca ccg tgc cca atg atg gtg gtt 979 Thr Ser Arg Ala Leu Leu Gln Ser Ala Pro Cys Pro Met Met Val Val 280 285 290 cgc cca cct gag aag att aag aag tagtttcttt taagtttcga tgc 1026 Arg Pro Pro Glu Lys Ile Lys Lys 295 300 <210> 14 <211> 301 <212> PRT <213> Corynebacterium glutamicum <400> 14 Met Ser Thr Glu Asp Ile Val Val Val Ala Val Asp Gly Ser Asp Ala 1 5 10 15 Ser Lys Gln Ala Val Arg Trp Ala Ala Asn Thr Ala Asn Lys Arg Gly 20 25 30 Ile Pro Leu Arg Leu Ala Ser Ser Tyr Thr Met Pro Gln Phe Leu Tyr 35 40 45 Ala Glu Gly Met Val Pro Pro Gln Glu Leu Phe Asp Asp Leu Gln Ala 50 55 60 Glu Ala Leu Glu Lys Ile Asn Glu Ala Arg Asp Ile Ala His Glu Val 65 70 75 80 Ala Pro Glu Ile Lys Ile Gly His Thr Ile Ala Glu Gly Ser Pro Ile 85 90 95 Asp Met Leu Leu Glu Met Ser Pro Asp Ala Thr Met Ile Val Met Gly 100 105 110 Ser Arg Gly Leu Gly Gly Leu Ser Gly Met Val Met Gly Ser Val Ser 115 120 125 Gly Ala Val Val Ser His Ala Lys Cys Pro Val Val Val Val Arg Glu 130 135 140 Asp Ser Ala Val Asn Glu Asp Ser Lys Tyr Gly Pro Val Val Val Gly 145 150 155 160 Val Asp Gly Ser Glu Val Ser Gln Gln Ala Thr Glu Tyr Ala Phe Ala 165 170 175 Glu Ala Glu Ala Arg Gly Ala Glu Leu Val Ala Val His Thr Trp Met 180 185 190 Asp Met Gln Val Gln Ala Ser Leu Ala Gly Leu Ala Ala Ala Gln Gln 195 200 205 Gln Trp Asp Glu Val Glu Arg Gln Gln Thr Asp Met Leu Ile Glu Arg 210 215 220 Leu Ala Pro Leu Val Glu Lys Tyr Pro Ser Val Thr Val Lys Lys Ile 225 230 235 240 Ile Thr Arg Asp Arg Pro Val Arg Ala Leu Ala Glu Ala Ser Glu Asn 245 250 255 Ala Gln Leu Leu Val Val Gly Ser His Gly Arg Gly Gly Phe Lys Gly 260 265 270 Met Leu Leu Gly Ser Thr Ser Arg Ala Leu Leu Gln Ser Ala Pro Cys 275 280 285 Pro Met Met Val Val Arg Pro Pro Glu Lys Ile Lys Lys 290 295 300 <210> 15 <211> 1059 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1036) <223> RXC00552 <400> 15 ccgccaacaa ggcagcaaag ctcgatccaa ttgacgcctt gcgttatgag taaaagcctc 60 gtttttaagg tagccacaca tcgcactaga ctgaagaact gtg gct acc tca aaa 115 Val Ala Thr Ser Lys 1 5 att ctt ctt tat tac gca ttc acc ccg ctc tct gac cct aaa gcg gtt 163 Ile Leu Leu Tyr Tyr Ala Phe Thr Pro Leu Ser Asp Pro Lys Ala Val 10 15 20 cag ctg tgg cag cgt gag ctc tgc gag tca ctg aat ctt cgt ggc cgc 211 Gln Leu Trp Gln Arg Glu Leu Cys Glu Ser Leu Asn Leu Arg Gly Arg 25 30 35 atc ctg atc tcc act cac ggc atc aat gga acc gtg ggc gga gat att 259 Ile Leu Ile Ser Thr His Gly Ile Asn Gly Thr Val Gly Gly Asp Ile 40 45 50 gat gat tgc aag gcg tac att aaa aag acc cgc gag tac cca ggt ttc 307 Asp Asp Cys Lys Ala Tyr Ile Lys Lys Thr Arg Glu Tyr Pro Gly Phe 55 60 65 aac cgc atg cag ttt aag tgg tcc gag ggt ggc gct gag gat ttc cca 355 Asn Arg Met Gln Phe Lys Trp Ser Glu Gly Gly Ala Glu Asp Phe Pro 70 75 80 85 aag ctc agt gtc aaa gtc cgc gat gag atc gtt gcc ttc ggc gct cca 403 Lys Leu Ser Val Lys Val Arg Asp Glu Ile Val Ala Phe Gly Ala Pro 90 95 100 gat gag ctc aaa gtg gat gaa aac ggc gtc gtc ggt ggc ggc gtt cac 451 Asp Glu Leu Lys Val Asp Glu Asn Gly Val Val Gly Gly Gly Val His 105 110 115 ctg aaa cca cag cag gtc aat gag ctt gtg gaa gcc cgt ggc gat gaa 499 Leu Lys Pro Gln Gln Val Asn Glu Leu Val Glu Ala Arg Gly Asp Glu 120 125 130 gtt gtg ttc ttt gac ggc cgc aac gca atg gaa gcc cag atc ggc aag 547 Val Val Phe Phe Asp Gly Arg Asn Ala Met Glu Ala Gln Ile Gly Lys 135 140 145 ttc aag gac gct gtt gtc cct gac gta gaa acc act cat gat ttc atc 595 Phe Lys Asp Ala Val Val Pro Asp Val Glu Thr Thr His Asp Phe Ile 150 155 160 165 gca gaa att gag tct gga aaa tac gac gat ctc aaa gac aag cct gtg 643 Ala Glu Ile Glu Ser Gly Lys Tyr Asp Asp Leu Lys Asp Lys Pro Val 170 175 180 gtc acc tac tgc acc ggc gga att cgt tgt gag atc ctg agt tca ctc 691 Val Thr Tyr Cys Thr Gly Gly Ile Arg Cys Glu Ile Leu Ser Ser Leu 185 190 195 atg atc aac cgt ggt ttc aaa gag gtc tac caa atc gat ggc ggc atc 739 Met Ile Asn Arg Gly Phe Lys Glu Val Tyr Gln Ile Asp Gly Gly Ile 200 205 210 gtt cgc tac ggc gag cag ttt ggc aac aag ggc ctg tgg gaa ggc tcc 787 Val Arg Tyr Gly Glu Gln Phe Gly Asn Lys Gly Leu Trp Glu Gly Ser 215 220 225 ctc tac gtt ttc gat aag cgc atg cat atg gaa ttc ggc gag gat tac 835 Leu Tyr Val Phe Asp Lys Arg Met His Met Glu Phe Gly Glu Asp Tyr 230 235 240 245 aaa gag gtc gga cac tgc atc cat tgc gat act ccc acc aac aaa ttt 883 Lys Glu Val Gly His Cys Ile His Cys Asp Thr Pro Thr Asn Lys Phe 250 255 260 gag cac tgc ctc aac gaa gat gat tgc cgc gag ctc gtg ttg atg tgc 931 Glu His Cys Leu Asn Glu Asp Asp Cys Arg Glu Leu Val Leu Met Cys 265 270 275 cct gat tgc ttc gcc aat gtt gag acc cgt cat tgc aag cgc gaa cgc 979 Pro Asp Cys Phe Ala Asn Val Glu Thr Arg His Cys Lys Arg Glu Arg 280 285 290 tgt gca gca att gct gcg gat ttc gct gag caa gga att gat ccg ctc 1027 Cys Ala Ala Ile Ala Ala Asp Phe Ala Glu Gln Gly Ile Asp Pro Leu 295 300 305 gtt act tct taaaaagggt atggtggctg ggt 1059 Val Thr Ser 310 <210> 16 <211> 312 <212> PRT <213> Corynebacterium glutamicum <400> 16 Val Ala Thr Ser Lys Ile Leu Leu Tyr Tyr Ala Phe Thr Pro Leu Ser 1 5 10 15 Asp Pro Lys Ala Val Gln Leu Trp Gln Arg Glu Leu Cys Glu Ser Leu 20 25 30 Asn Leu Arg Gly Arg Ile Leu Ile Ser Thr His Gly Ile Asn Gly Thr 35 40 45 Val Gly Gly Asp Ile Asp Asp Cys Lys Ala Tyr Ile Lys Lys Thr Arg 50 55 60 Glu Tyr Pro Gly Phe Asn Arg Met Gln Phe Lys Trp Ser Glu Gly Gly 65 70 75 80 Ala Glu Asp Phe Pro Lys Leu Ser Val Lys Val Arg Asp Glu Ile Val 85 90 95 Ala Phe Gly Ala Pro Asp Glu Leu Lys Val Asp Glu Asn Gly Val Val 100 105 110 Gly Gly Gly Val His Leu Lys Pro Gln Gln Val Asn Glu Leu Val Glu 115 120 125 Ala Arg Gly Asp Glu Val Val Phe Phe Asp Gly Arg Asn Ala Met Glu 130 135 140 Ala Gln Ile Gly Lys Phe Lys Asp Ala Val Val Pro Asp Val Glu Thr 145 150 155 160 Thr His Asp Phe Ile Ala Glu Ile Glu Ser Gly Lys Tyr Asp Asp Leu 165 170 175 Lys Asp Lys Pro Val Val Thr Tyr Cys Thr Gly Gly Ile Arg Cys Glu 180 185 190 Ile Leu Ser Ser Leu Met Ile Asn Arg Gly Phe Lys Glu Val Tyr Gln 195 200 205 Ile Asp Gly Gly Ile Val Arg Tyr Gly Glu Gln Phe Gly Asn Lys Gly 210 215 220 Leu Trp Glu Gly Ser Leu Tyr Val Phe Asp Lys Arg Met His Met Glu 225 230 235 240 Phe Gly Glu Asp Tyr Lys Glu Val Gly His Cys Ile His Cys Asp Thr 245 250 255 Pro Thr Asn Lys Phe Glu His Cys Leu Asn Glu Asp Asp Cys Arg Glu 260 265 270 Leu Val Leu Met Cys Pro Asp Cys Phe Ala Asn Val Glu Thr Arg His 275 280 285 Cys Lys Arg Glu Arg Cys Ala Ala Ile Ala Ala Asp Phe Ala Glu Gln 290 295 300 Gly Ile Asp Pro Leu Val Thr Ser 305 310 <210> 17 <211> 1578 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1555) <223> RXN00351 <400> 17 gaaggctgct gctaagaaaa cgaccaagaa gaccactaag aaaactacta aaaagaccac 60 cgcaaagaag accacaaaga agtcttaagc cggatcttat atg gat gat tcc aat 115 Met Asp Asp Ser Asn 1 5 agc ttt gta gtt gtt gct aac cgt ctg cca gtg gat atg act gtc cac 163 Ser Phe Val Val Val Ala Asn Arg Leu Pro Val Asp Met Thr Val His 10 15 20 cca gat ggt agc tat agc atc tcc ccc agc ccc ggt ggc ctt gtc acg 211 Pro Asp Gly Ser Tyr Ser Ile Ser Pro Ser Pro Gly Gly Leu Val Thr 25 30 35 ggg ctt tcc ccc gtt ctg gaa caa cat cgt gga tgt tgg gtc gga tgg 259 Gly Leu Ser Pro Val Leu Glu Gln His Arg Gly Cys Trp Val Gly Trp 40 45 50 cct gga act gta gat gtt gca ccc gaa cca ttt cga aca gat acg ggt 307 Pro Gly Thr Val Asp Val Ala Pro Glu Pro Phe Arg Thr Asp Thr Gly 55 60 65 gtt ttg ctg cac cct gtt gtc ctc act gca agt gac tat gaa ggc ttc 355 Val Leu Leu His Pro Val Val Leu Thr Ala Ser Asp Tyr Glu Gly Phe 70 75 80 85 tac gag ggc ttt tca aac gca acg ctg tgg cct ctt ttc cac gat ctg 403 Tyr Glu Gly Phe Ser Asn Ala Thr Leu Trp Pro Leu Phe His Asp Leu 90 95 100 att gtt act ccg gtg tac aac acc gat tgg tgg cat gcg ttt cgg gag 451 Ile Val Thr Pro Val Tyr Asn Thr Asp Trp Trp His Ala Phe Arg Glu 105 110 115 gta aac ctc aag ttc gct gaa gcc gtg agc caa gtg gcg gca cac ggt 499 Val Asn Leu Lys Phe Ala Glu Ala Val Ser Gln Val Ala Ala His Gly 120 125 130 gcc act gtg tgg gtg cag gac tat cag ctg ttg ctg gtt cct ggc att 547 Ala Thr Val Trp Val Gln Asp Tyr Gln Leu Leu Leu Val Pro Gly Ile 135 140 145 ttg cgc cag atg cgc cct gat ttg aag atc ggt ttc ttc ctc cac att 595 Leu Arg Gln Met Arg Pro Asp Leu Lys Ile Gly Phe Phe Leu His Ile 150 155 160 165 ccc ttc cct tcc cct gat ctg ttc cgt cag ctg ccg tgg cgt gaa gag 643 Pro Phe Pro Ser Pro Asp Leu Phe Arg Gln Leu Pro Trp Arg Glu Glu 170 175 180 att gtt cga ggc atg ctg ggc gca gat ttg gtg gga ttc cat ttg gtt 691 Ile Val Arg Gly Met Leu Gly Ala Asp Leu Val Gly Phe His Leu Val 185 190 195 caa aac gca gaa aac ttc ctt gcg tta acc cag cag gtt gcc ggc act 739 Gln Asn Ala Glu Asn Phe Leu Ala Leu Thr Gln Gln Val Ala Gly Thr 200 205 210 gcc ggg tct cat gtg ggt cag ccg gac acc ttg cag gtc agt ggt gaa 787 Ala Gly Ser His Val Gly Gln Pro Asp Thr Leu Gln Val Ser Gly Glu 215 220 225 gca ttg gtg cgt gag att ggc gct cat gtt gaa acc gct gac gga agg 835 Ala Leu Val Arg Glu Ile Gly Ala His Val Glu Thr Ala Asp Gly Arg 230 235 240 245 cga gtt agc gtc ggg gcg ttc ccg atc tcg att gat gtt gaa atg ttt 883 Arg Val Ser Val Gly Ala Phe Pro Ile Ser Ile Asp Val Glu Met Phe 250 255 260 ggg gag gcg tcg aaa agc gcc gtt ctt gat ctt tta aaa acg ctc gac 931 Gly Glu Ala Ser Lys Ser Ala Val Leu Asp Leu Leu Lys Thr Leu Asp 265 270 275 gag ccg gaa acc gta ttc ctg ggc gtt gac cga ctg gac tac acc aag 979 Glu Pro Glu Thr Val Phe Leu Gly Val Asp Arg Leu Asp Tyr Thr Lys 280 285 290 ggc att ttg cag cgc ctg ctt gcg ttt gag gaa ctg ctg gaa tcc ggc 1027 Gly Ile Leu Gln Arg Leu Leu Ala Phe Glu Glu Leu Leu Glu Ser Gly 295 300 305 gcg ttg gag gcc gac aaa gct gtg ttg ctg cag gtc gcg acg cct tcg 1075 Ala Leu Glu Ala Asp Lys Ala Val Leu Leu Gln Val Ala Thr Pro Ser 310 315 320 325 cgt gag cgc att gat cac tat cgt gtg tcg cgt tcg cag gtc gag gaa 1123 Arg Glu Arg Ile Asp His Tyr Arg Val Ser Arg Ser Gln Val Glu Glu 330 335 340 gcc gtc ggc cgt atc aat ggt cgt ttc ggt cgc atg ggg cgt ccc gtg 1171 Ala Val Gly Arg Ile Asn Gly Arg Phe Gly Arg Met Gly Arg Pro Val 345 350 355 gtg cat tat cta cac agg tca ttg agc aaa aat gat ctc cag gtg ctg 1219 Val His Tyr Leu His Arg Ser Leu Ser Lys Asn Asp Leu Gln Val Leu 360 365 370 tat acc gca gcc gat gtc atg ctg gtt acg cct ttt aaa gac ggt atg 1267 Tyr Thr Ala Ala Asp Val Met Leu Val Thr Pro Phe Lys Asp Gly Met 375 380 385 aac ttg gtg gct aaa gaa ttc gtg gcc aac cac cgc gac ggc act ggt 1315 Asn Leu Val Ala Lys Glu Phe Val Ala Asn His Arg Asp Gly Thr Gly 390 395 400 405 gct ttg gtg ctg tcc gaa ttt gcc ggc gcg gcc act gag ctg acc ggt 1363 Ala Leu Val Leu Ser Glu Phe Ala Gly Ala Ala Thr Glu Leu Thr Gly 410 415 420 gcg tat tta tgc aac cca ttt gat gtg gaa tcc atc aaa cgg caa atg 1411 Ala Tyr Leu Cys Asn Pro Phe Asp Val Glu Ser Ile Lys Arg Gln Met 425 430 435 gtg gca gct gtc cat gat ttg aag cac aat ccg gaa tct gcg gca acg 1459 Val Ala Ala Val His Asp Leu Lys His Asn Pro Glu Ser Ala Ala Thr 440 445 450 cga atg aaa acg aac agc gag cag gtc tat acc cac gac gtc aac gtg 1507 Arg Met Lys Thr Asn Ser Glu Gln Val Tyr Thr His Asp Val Asn Val 455 460 465 tgg gct aat agt ttc ctg gat tgt ttg gca cag tcg gga gaa aac tca 1555 Trp Ala Asn Ser Phe Leu Asp Cys Leu Ala Gln Ser Gly Glu Asn Ser 470 475 480 485 tgaaccgcgc acgaatcgcg acc 1578 <210> 18 <211> 485 <212> PRT <213> Corynebacterium glutamicum <400> 18 Met Asp Asp Ser Asn Ser Phe Val Val Val Ala Asn Arg Leu Pro Val 1 5 10 15 Asp Met Thr Val His Pro Asp Gly Ser Tyr Ser Ile Ser Pro Ser Pro 20 25 30 Gly Gly Leu Val Thr Gly Leu Ser Pro Val Leu Glu Gln His Arg Gly 35 40 45 Cys Trp Val Gly Trp Pro Gly Thr Val Asp Val Ala Pro Glu Pro Phe 50 55 60 Arg Thr Asp Thr Gly Val Leu Leu His Pro Val Val Leu Thr Ala Ser 65 70 75 80 Asp Tyr Glu Gly Phe Tyr Glu Gly Phe Ser Asn Ala Thr Leu Trp Pro 85 90 95 Leu Phe His Asp Leu Ile Val Thr Pro Val Tyr Asn Thr Asp Trp Trp 100 105 110 His Ala Phe Arg Glu Val Asn Leu Lys Phe Ala Glu Ala Val Ser Gln 115 120 125 Val Ala Ala His Gly Ala Thr Val Trp Val Gln Asp Tyr Gln Leu Leu 130 135 140 Leu Val Pro Gly Ile Leu Arg Gln Met Arg Pro Asp Leu Lys Ile Gly 145 150 155 160 Phe Phe Leu His Ile Pro Phe Pro Ser Pro Asp Leu Phe Arg Gln Leu 165 170 175 Pro Trp Arg Glu Glu Ile Val Arg Gly Met Leu Gly Ala Asp Leu Val 180 185 190 Gly Phe His Leu Val Gln Asn Ala Glu Asn Phe Leu Ala Leu Thr Gln 195 200 205 Gln Val Ala Gly Thr Ala Gly Ser His Val Gly Gln Pro Asp Thr Leu 210 215 220 Gln Val Ser Gly Glu Ala Leu Val Arg Glu Ile Gly Ala His Val Glu 225 230 235 240 Thr Ala Asp Gly Arg Arg Val Ser Val Gly Ala Phe Pro Ile Ser Ile 245 250 255 Asp Val Glu Met Phe Gly Glu Ala Ser Lys Ser Ala Val Leu Asp Leu 260 265 270 Leu Lys Thr Leu Asp Glu Pro Glu Thr Val Phe Leu Gly Val Asp Arg 275 280 285 Leu Asp Tyr Thr Lys Gly Ile Leu Gln Arg Leu Leu Ala Phe Glu Glu 290 295 300 Leu Leu Glu Ser Gly Ala Leu Glu Ala Asp Lys Ala Val Leu Leu Gln 305 310 315 320 Val Ala Thr Pro Ser Arg Glu Arg Ile Asp His Tyr Arg Val Ser Arg 325 330 335 Ser Gln Val Glu Glu Ala Val Gly Arg Ile Asn Gly Arg Phe Gly Arg 340 345 350 Met Gly Arg Pro Val Val His Tyr Leu His Arg Ser Leu Ser Lys Asn 355 360 365 Asp Leu Gln Val Leu Tyr Thr Ala Ala Asp Val Met Leu Val Thr Pro 370 375 380 Phe Lys Asp Gly Met Asn Leu Val Ala Lys Glu Phe Val Ala Asn His 385 390 395 400 Arg Asp Gly Thr Gly Ala Leu Val Leu Ser Glu Phe Ala Gly Ala Ala 405 410 415 Thr Glu Leu Thr Gly Ala Tyr Leu Cys Asn Pro Phe Asp Val Glu Ser 420 425 430 Ile Lys Arg Gln Met Val Ala Ala Val His Asp Leu Lys His Asn Pro 435 440 445 Glu Ser Ala Ala Thr Arg Met Lys Thr Asn Ser Glu Gln Val Tyr Thr 450 455 460 His Asp Val Asn Val Trp Ala Asn Ser Phe Leu Asp Cys Leu Ala Gln 465 470 475 480 Ser Gly Glu Asn Ser 485 <210> 19 <211> 1546 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1546) <223> FRXA00351 <400> 19 gaaggctgct gctaagaaaa cgaccaagaa gaccactaag aaaactacta aaaagaccac 60 cgcaaagaag accacaaaga agtcttaagc cggatcttat atg gat gat tcc aat 115 Met Asp Asp Ser Asn 1 5 agc ttt gta gtt gtt gct aac cgt ctg cca gtg gat atg act gtc cac 163 Ser Phe Val Val Val Ala Asn Arg Leu Pro Val Asp Met Thr Val His 10 15 20 cca gat ggt agc tat agc atc tcc ccc agc ccc ggt ggc ctt gtc acg 211 Pro Asp Gly Ser Tyr Ser Ile Ser Pro Ser Pro Gly Gly Leu Val Thr 25 30 35 ggg ctt tcc ccc gtt ctg gaa caa cat cgt gga tgt tgg gtc gga tgg 259 Gly Leu Ser Pro Val Leu Glu Gln His Arg Gly Cys Trp Val Gly Trp 40 45 50 cct gga act gta gat gtt gca ccc gaa cca ttt cga aca gat acg ggt 307 Pro Gly Thr Val Asp Val Ala Pro Glu Pro Phe Arg Thr Asp Thr Gly 55 60 65 gtt ttg ctg cac cct gtt gtc ctc act gca agt gac tat gaa ggc ttc 355 Val Leu Leu His Pro Val Val Leu Thr Ala Ser Asp Tyr Glu Gly Phe 70 75 80 85 tac gag ggc ttt tca aac gca acg ctg tgg cct ctt ttc cac gat ctg 403 Tyr Glu Gly Phe Ser Asn Ala Thr Leu Trp Pro Leu Phe His Asp Leu 90 95 100 att gtt act ccg gtg tac aac acc gat tgg tgg cat gcg ttt cgg gag 451 Ile Val Thr Pro Val Tyr Asn Thr Asp Trp Trp His Ala Phe Arg Glu 105 110 115 gta aac ctc aag ttc gct gaa gcc gtg agc caa gtg gcg gca cac ggt 499 Val Asn Leu Lys Phe Ala Glu Ala Val Ser Gln Val Ala Ala His Gly 120 125 130 gcc act gtg tgg gtg cag gac tat cag ctg ttg ctg gtt cct ggc att 547 Ala Thr Val Trp Val Gln Asp Tyr Gln Leu Leu Leu Val Pro Gly Ile 135 140 145 ttg cgc cag atg cgc cct gat ttg aag atc ggt ttc ttc ctc cac att 595 Leu Arg Gln Met Arg Pro Asp Leu Lys Ile Gly Phe Phe Leu His Ile 150 155 160 165 ccc ttc cct tcc cct gat ctg ttc cgt cag ctg ccg tgg cgt gaa gag 643 Pro Phe Pro Ser Pro Asp Leu Phe Arg Gln Leu Pro Trp Arg Glu Glu 170 175 180 att gtt cga ggc atg ctg ggc gca gat ttg gtg gga ttc cat ttg gtt 691 Ile Val Arg Gly Met Leu Gly Ala Asp Leu Val Gly Phe His Leu Val 185 190 195 caa aac gca gaa aac ttc ctt gcg tta acc cag cag gtt gcc ggc act 739 Gln Asn Ala Glu Asn Phe Leu Ala Leu Thr Gln Gln Val Ala Gly Thr 200 205 210 gcc ggg tct cat gtg ggt cag ccg gac acc ttg cag gtc agt ggt gaa 787 Ala Gly Ser His Val Gly Gln Pro Asp Thr Leu Gln Val Ser Gly Glu 215 220 225 gca ttg gtg cgt gag att ggc gct cat gtt gaa acc gct gac gga agg 835 Ala Leu Val Arg Glu Ile Gly Ala His Val Glu Thr Ala Asp Gly Arg 230 235 240 245 cga gtt agc gtc ggg gcg ttc ccg atc tcg att gat gtt gaa atg ttt 883 Arg Val Ser Val Gly Ala Phe Pro Ile Ser Ile Asp Val Glu Met Phe 250 255 260 ggg gag gcg tcg aaa agc gcc gtt ctt gat ctt tta aaa acg ctc gac 931 Gly Glu Ala Ser Lys Ser Ala Val Leu Asp Leu Leu Lys Thr Leu Asp 265 270 275 gag ccg gaa acc gta ttc ctg ggc gtt gac cga ctg gac tac acc aag 979 Glu Pro Glu Thr Val Phe Leu Gly Val Asp Arg Leu Asp Tyr Thr Lys 280 285 290 ggc att ttg cag cgc ctg ctt gcg ttt gag gaa ctg ctg gaa tcc ggc 1027 Gly Ile Leu Gln Arg Leu Leu Ala Phe Glu Glu Leu Leu Glu Ser Gly 295 300 305 gcg ttg gag gcc gac aaa gct gtg ttg ctg cag gtc gcg acg cct tcg 1075 Ala Leu Glu Ala Asp Lys Ala Val Leu Leu Gln Val Ala Thr Pro Ser 310 315 320 325 cgt gag cgc att gat cac tat cgt gtg tcg cgt tcg cag gtc gag gaa 1123 Arg Glu Arg Ile Asp His Tyr Arg Val Ser Arg Ser Gln Val Glu Glu 330 335 340 gcc gtc ggc cgt atc aat ggt cgt ttc ggt cgc atg ggg cgt ccc gtg 1171 Ala Val Gly Arg Ile Asn Gly Arg Phe Gly Arg Met Gly Arg Pro Val 345 350 355 gtg cat tat cta cac agg tca ttg agc aaa aat gat ctc cag gtg ctg 1219 Val His Tyr Leu His Arg Ser Leu Ser Lys Asn Asp Leu Gln Val Leu 360 365 370 tat acc gca gcc gat gtc atg ctg gtt acg cct ttt aaa gac ggt atg 1267 Tyr Thr Ala Ala Asp Val Met Leu Val Thr Pro Phe Lys Asp Gly Met 375 380 385 aac ttg gtg gct aaa gaa ttc gtg gcc aac cac cgc gac ggc act ggt 1315 Asn Leu Val Ala Lys Glu Phe Val Ala Asn His Arg Asp Gly Thr Gly 390 395 400 405 gct ttg gtg ctg tcc gaa ttt gcc ggc gcg gcc act gag ctg acc ggt 1363 Ala Leu Val Leu Ser Glu Phe Ala Gly Ala Ala Thr Glu Leu Thr Gly 410 415 420 gcg tat tta tgc aac cca ttt gat gtg gaa tcc atc aaa cgg caa atg 1411 Ala Tyr Leu Cys Asn Pro Phe Asp Val Glu Ser Ile Lys Arg Gln Met 425 430 435 gtg gca gct gtc cat gat ttg aag cac aat ccg gaa tct gcg gca acg 1459 Val Ala Ala Val His Asp Leu Lys His Asn Pro Glu Ser Ala Ala Thr 440 445 450 cga atg aaa acg aac agc gag cag gtc tat acc cac gac gtc aac gtg 1507 Arg Met Lys Thr Asn Ser Glu Gln Val Tyr Thr His Asp Val Asn Val 455 460 465 tgg gct aat agt ttc ctg gat tgt ttg gca cag tcg gga 1546 Trp Ala Asn Ser Phe Leu Asp Cys Leu Ala Gln Ser Gly 470 475 480 <210> 20 <211> 482 <212> PRT <213> Corynebacterium glutamicum <400> 20 Met Asp Asp Ser Asn Ser Phe Val Val Val Ala Asn Arg Leu Pro Val 1 5 10 15 Asp Met Thr Val His Pro Asp Gly Ser Tyr Ser Ile Ser Pro Ser Pro 20 25 30 Gly Gly Leu Val Thr Gly Leu Ser Pro Val Leu Glu Gln His Arg Gly 35 40 45 Cys Trp Val Gly Trp Pro Gly Thr Val Asp Val Ala Pro Glu Pro Phe 50 55 60 Arg Thr Asp Thr Gly Val Leu Leu His Pro Val Val Leu Thr Ala Ser 65 70 75 80 Asp Tyr Glu Gly Phe Tyr Glu Gly Phe Ser Asn Ala Thr Leu Trp Pro 85 90 95 Leu Phe His Asp Leu Ile Val Thr Pro Val Tyr Asn Thr Asp Trp Trp 100 105 110 His Ala Phe Arg Glu Val Asn Leu Lys Phe Ala Glu Ala Val Ser Gln 115 120 125 Val Ala Ala His Gly Ala Thr Val Trp Val Gln Asp Tyr Gln Leu Leu 130 135 140 Leu Val Pro Gly Ile Leu Arg Gln Met Arg Pro Asp Leu Lys Ile Gly 145 150 155 160 Phe Phe Leu His Ile Pro Phe Pro Ser Pro Asp Leu Phe Arg Gln Leu 165 170 175 Pro Trp Arg Glu Glu Ile Val Arg Gly Met Leu Gly Ala Asp Leu Val 180 185 190 Gly Phe His Leu Val Gln Asn Ala Glu Asn Phe Leu Ala Leu Thr Gln 195 200 205 Gln Val Ala Gly Thr Ala Gly Ser His Val Gly Gln Pro Asp Thr Leu 210 215 220 Gln Val Ser Gly Glu Ala Leu Val Arg Glu Ile Gly Ala His Val Glu 225 230 235 240 Thr Ala Asp Gly Arg Arg Val Ser Val Gly Ala Phe Pro Ile Ser Ile 245 250 255 Asp Val Glu Met Phe Gly Glu Ala Ser Lys Ser Ala Val Leu Asp Leu 260 265 270 Leu Lys Thr Leu Asp Glu Pro Glu Thr Val Phe Leu Gly Val Asp Arg 275 280 285 Leu Asp Tyr Thr Lys Gly Ile Leu Gln Arg Leu Leu Ala Phe Glu Glu 290 295 300 Leu Leu Glu Ser Gly Ala Leu Glu Ala Asp Lys Ala Val Leu Leu Gln 305 310 315 320 Val Ala Thr Pro Ser Arg Glu Arg Ile Asp His Tyr Arg Val Ser Arg 325 330 335 Ser Gln Val Glu Glu Ala Val Gly Arg Ile Asn Gly Arg Phe Gly Arg 340 345 350 Met Gly Arg Pro Val Val His Tyr Leu His Arg Ser Leu Ser Lys Asn 355 360 365 Asp Leu Gln Val Leu Tyr Thr Ala Ala Asp Val Met Leu Val Thr Pro 370 375 380 Phe Lys Asp Gly Met Asn Leu Val Ala Lys Glu Phe Val Ala Asn His 385 390 395 400 Arg Asp Gly Thr Gly Ala Leu Val Leu Ser Glu Phe Ala Gly Ala Ala 405 410 415 Thr Glu Leu Thr Gly Ala Tyr Leu Cys Asn Pro Phe Asp Val Glu Ser 420 425 430 Ile Lys Arg Gln Met Val Ala Ala Val His Asp Leu Lys His Asn Pro 435 440 445 Glu Ser Ala Ala Thr Arg Met Lys Thr Asn Ser Glu Gln Val Tyr Thr 450 455 460 His Asp Val Asn Val Trp Ala Asn Ser Phe Leu Asp Cys Leu Ala Gln 465 470 475 480 Ser Gly <210> 21 <211> 779 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(756) <223> RXA00873 <400> 21 act gcc caa tgg ggt att ttc ctg cgt aat cat gat gag ctc acc ctt 48 Thr Ala Gln Trp Gly Ile Phe Leu Arg Asn His Asp Glu Leu Thr Leu 1 5 10 15 gaa atg gtc tcc gat gag gaa cgc agc tac atg tac tcc caa ttc gcc 96 Glu Met Val Ser Asp Glu Glu Arg Ser Tyr Met Tyr Ser Gln Phe Ala 20 25 30 tcc gaa cct cgc atg cgc gcc aac gta gga atc cgc agg cgc ctt tcc 144 Ser Glu Pro Arg Met Arg Ala Asn Val Gly Ile Arg Arg Arg Leu Ser 35 40 45 cca ctg ctt gaa ggc gac cgc aac cag ctg gaa ctc ctt cac ggt ttg 192 Pro Leu Leu Glu Gly Asp Arg Asn Gln Leu Glu Leu Leu His Gly Leu 50 55 60 ttg ctg tct cta cct ggc tca ccc gtg ttg tat tac ggt gat gaa att 240 Leu Leu Ser Leu Pro Gly Ser Pro Val Leu Tyr Tyr Gly Asp Glu Ile 65 70 75 80 ggc atg ggc gac aat atc tgg ctc cac gac cgc gac gga gtg cgc acc 288 Gly Met Gly Asp Asn Ile Trp Leu His Asp Arg Asp Gly Val Arg Thr 85 90 95 ccc atg cag tgg tcc aac gac cgc aac ggt ggt ttc tcc aaa gct gat 336 Pro Met Gln Trp Ser Asn Asp Arg Asn Gly Gly Phe Ser Lys Ala Asp 100 105 110 cct gaa cgc ctg tac ctt cca gcg atc caa aat gat caa tac ggc tac 384 Pro Glu Arg Leu Tyr Leu Pro Ala Ile Gln Asn Asp Gln Tyr Gly Tyr 115 120 125 gcc caa gta aac gtg gaa agc caa ctc aac cgc gaa aac tcc ctg ctg 432 Ala Gln Val Asn Val Glu Ser Gln Leu Asn Arg Glu Asn Ser Leu Leu 130 135 140 cgc tgg ctc cga aac caa atc ctt atc cgc aag cag tac cgc gca ttt 480 Arg Trp Leu Arg Asn Gln Ile Leu Ile Arg Lys Gln Tyr Arg Ala Phe 145 150 155 160 ggt gcc gga acc tac cgt gaa gtg tcc tcc acc aat gag tca gtg ttg 528 Gly Ala Gly Thr Tyr Arg Glu Val Ser Ser Thr Asn Glu Ser Val Leu 165 170 175 aca ttt tta cga gaa cac aag ggc caa acc att ttg tgt gtc aac aac 576 Thr Phe Leu Arg Glu His Lys Gly Gln Thr Ile Leu Cys Val Asn Asn 180 185 190 atg agc aaa tat cct cag gca gtc tcg ctt gat ttg cgt gaa ttt gca 624 Met Ser Lys Tyr Pro Gln Ala Val Ser Leu Asp Leu Arg Glu Phe Ala 195 200 205 gga cac acc cct cga gag atg tcg ggc ggg cag ctg ttc cct acc att 672 Gly His Thr Pro Arg Glu Met Ser Gly Gly Gln Leu Phe Pro Thr Ile 210 215 220 gct gaa cgg gag tgg att gtc act tta gcc cct cac gga ttc ttc tgg 720 Ala Glu Arg Glu Trp Ile Val Thr Leu Ala Pro His Gly Phe Phe Trp 225 230 235 240 ttt gat ctc acc gcc gat gaa aag gac gat atg gaa tgagcattgg 766 Phe Asp Leu Thr Ala Asp Glu Lys Asp Asp Met Glu 245 250 ccaacacatc atc 779 <210> 22 <211> 252 <212> PRT <213> Corynebacterium glutamicum <400> 22 Thr Ala Gln Trp Gly Ile Phe Leu Arg Asn His Asp Glu Leu Thr Leu 1 5 10 15 Glu Met Val Ser Asp Glu Glu Arg Ser Tyr Met Tyr Ser Gln Phe Ala 20 25 30 Ser Glu Pro Arg Met Arg Ala Asn Val Gly Ile Arg Arg Arg Leu Ser 35 40 45 Pro Leu Leu Glu Gly Asp Arg Asn Gln Leu Glu Leu Leu His Gly Leu 50 55 60 Leu Leu Ser Leu Pro Gly Ser Pro Val Leu Tyr Tyr Gly Asp Glu Ile 65 70 75 80 Gly Met Gly Asp Asn Ile Trp Leu His Asp Arg Asp Gly Val Arg Thr 85 90 95 Pro Met Gln Trp Ser Asn Asp Arg Asn Gly Gly Phe Ser Lys Ala Asp 100 105 110 Pro Glu Arg Leu Tyr Leu Pro Ala Ile Gln Asn Asp Gln Tyr Gly Tyr 115 120 125 Ala Gln Val Asn Val Glu Ser Gln Leu Asn Arg Glu Asn Ser Leu Leu 130 135 140 Arg Trp Leu Arg Asn Gln Ile Leu Ile Arg Lys Gln Tyr Arg Ala Phe 145 150 155 160 Gly Ala Gly Thr Tyr Arg Glu Val Ser Ser Thr Asn Glu Ser Val Leu 165 170 175 Thr Phe Leu Arg Glu His Lys Gly Gln Thr Ile Leu Cys Val Asn Asn 180 185 190 Met Ser Lys Tyr Pro Gln Ala Val Ser Leu Asp Leu Arg Glu Phe Ala 195 200 205 Gly His Thr Pro Arg Glu Met Ser Gly Gly Gln Leu Phe Pro Thr Ile 210 215 220 Ala Glu Arg Glu Trp Ile Val Thr Leu Ala Pro His Gly Phe Phe Trp 225 230 235 240 Phe Asp Leu Thr Ala Asp Glu Lys Asp Asp Met Glu 245 250 <210> 23 <211> 1102 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1102) <223> RXA00891 <400> 23 tcaatattcc gaagaaaacc gcgcagctct ctcactagtc tcaggtgagg cgaaagtggt 60 gaaagacccg ctacgcatgg tgcgcctggc tttttagaat gtg ctg caa acc tcc 115 Val Leu Gln Thr Ser 1 5 tgg cat ttc tct atc ctg gca ggc atg act gat acc tct ccg ttg aat 163 Trp His Phe Ser Ile Leu Ala Gly Met Thr Asp Thr Ser Pro Leu Asn 10 15 20 tct cag ccg agt gca gat cac cac cct gat cac gcg gct cgc cca gtt 211 Ser Gln Pro Ser Ala Asp His His Pro Asp His Ala Ala Arg Pro Val 25 30 35 ctt gat gcc cac ggc ttg atc gtt gag cac gaa tcg gaa gag ttt cca 259 Leu Asp Ala His Gly Leu Ile Val Glu His Glu Ser Glu Glu Phe Pro 40 45 50 gtc ccc gca ccc gct ccc ggt gaa cag ccc tgg gag aag aaa aac cgc 307 Val Pro Ala Pro Ala Pro Gly Glu Gln Pro Trp Glu Lys Lys Asn Arg 55 60 65 gag tgg tac aaa gac gcc gtt ttc tac gaa gtg ctg gtt cgt gcc ttc 355 Glu Trp Tyr Lys Asp Ala Val Phe Tyr Glu Val Leu Val Arg Ala Phe 70 75 80 85 tac gat cca gaa ggc aac gga gtc gga tcg ttg aaa ggc ctg acc gaa 403 Tyr Asp Pro Glu Gly Asn Gly Val Gly Ser Leu Lys Gly Leu Thr Glu 90 95 100 aaa ctg gat tac atc cag tgg ctc ggc gtg gat tgc att tgg atc cca 451 Lys Leu Asp Tyr Ile Gln Trp Leu Gly Val Asp Cys Ile Trp Ile Pro 105 110 115 ccg ttt tat gat tcc cca ctg cgc gac ggc ggt tac gat atc cgc aac 499 Pro Phe Tyr Asp Ser Pro Leu Arg Asp Gly Gly Tyr Asp Ile Arg Asn 120 125 130 ttc cgt gaa atc ctg ccc gaa ttc ggc acc gtc gat gac ttc gtg gaa 547 Phe Arg Glu Ile Leu Pro Glu Phe Gly Thr Val Asp Asp Phe Val Glu 135 140 145 ctc gtt gac cac gcc cac cgc cgt ggc ctg cgt gtt atc acc gac ttg 595 Leu Val Asp His Ala His Arg Arg Gly Leu Arg Val Ile Thr Asp Leu 150 155 160 165 gtc atg aat cac acc tcc gac cag cac gca tgg ttc caa gaa tcc cgg 643 Val Met Asn His Thr Ser Asp Gln His Ala Trp Phe Gln Glu Ser Arg 170 175 180 cgc gac cca acc ggc ccc tac gga gat ttc tat gtg tgg agc gat gat 691 Arg Asp Pro Thr Gly Pro Tyr Gly Asp Phe Tyr Val Trp Ser Asp Asp 185 190 195 ccc acc ctg tac aac gaa gcc cgc atc atc ttt gta gat aca gaa gaa 739 Pro Thr Leu Tyr Asn Glu Ala Arg Ile Ile Phe Val Asp Thr Glu Glu 200 205 210 tcc aac tgg acc tat gat ccg gtg cgt ggc cag tac ttc tgg cac cgc 787 Ser Asn Trp Thr Tyr Asp Pro Val Arg Gly Gln Tyr Phe Trp His Arg 215 220 225 ttc ttc tcc cac caa cca gac ctc aac tac gac aac ccc gca gtc caa 835 Phe Phe Ser His Gln Pro Asp Leu Asn Tyr Asp Asn Pro Ala Val Gln 230 235 240 245 gag gcc atg cta gat gtc ttg cgt ttc tgg ctg gac ctg gga ctt gat 883 Glu Ala Met Leu Asp Val Leu Arg Phe Trp Leu Asp Leu Gly Leu Asp 250 255 260 ggt ttc cga cta gat gcc gtt cct tat ctt ttt gaa cgc gaa ggc acc 931 Gly Phe Arg Leu Asp Ala Val Pro Tyr Leu Phe Glu Arg Glu Gly Thr 265 270 275 aac ggc gaa aac ctc aaa gaa acc cac gat ttc ctc aaa ctg tgt cgc 979 Asn Gly Glu Asn Leu Lys Glu Thr His Asp Phe Leu Lys Leu Cys Arg 280 285 290 tct gtc att gag aag gaa tac ccc ggc cga atc ctg ctc gca gaa gcc 1027 Ser Val Ile Glu Lys Glu Tyr Pro Gly Arg Ile Leu Leu Ala Glu Ala 295 300 305 aac caa tgg ccc caa gat gtg gtc gaa tac ttc ggt gaa aaa gac aaa 1075 Asn Gln Trp Pro Gln Asp Val Val Glu Tyr Phe Gly Glu Lys Asp Lys 310 315 320 325 ggc gat gaa tgc cac atg gcc ttc cac 1102 Gly Asp Glu Cys His Met Ala Phe His 330 <210> 24 <211> 334 <212> PRT <213> Corynebacterium glutamicum <400> 24 Val Leu Gln Thr Ser Trp His Phe Ser Ile Leu Ala Gly Met Thr Asp 1 5 10 15 Thr Ser Pro Leu Asn Ser Gln Pro Ser Ala Asp His His Pro Asp His 20 25 30 Ala Ala Arg Pro Val Leu Asp Ala His Gly Leu Ile Val Glu His Glu 35 40 45 Ser Glu Glu Phe Pro Val Pro Ala Pro Ala Pro Gly Glu Gln Pro Trp 50 55 60 Glu Lys Lys Asn Arg Glu Trp Tyr Lys Asp Ala Val Phe Tyr Glu Val 65 70 75 80 Leu Val Arg Ala Phe Tyr Asp Pro Glu Gly Asn Gly Val Gly Ser Leu 85 90 95 Lys Gly Leu Thr Glu Lys Leu Asp Tyr Ile Gln Trp Leu Gly Val Asp 100 105 110 Cys Ile Trp Ile Pro Pro Phe Tyr Asp Ser Pro Leu Arg Asp Gly Gly 115 120 125 Tyr Asp Ile Arg Asn Phe Arg Glu Ile Leu Pro Glu Phe Gly Thr Val 130 135 140 Asp Asp Phe Val Glu Leu Val Asp His Ala His Arg Arg Gly Leu Arg 145 150 155 160 Val Ile Thr Asp Leu Val Met Asn His Thr Ser Asp Gln His Ala Trp 165 170 175 Phe Gln Glu Ser Arg Arg Asp Pro Thr Gly Pro Tyr Gly Asp Phe Tyr 180 185 190 Val Trp Ser Asp Asp Pro Thr Leu Tyr Asn Glu Ala Arg Ile Ile Phe 195 200 205 Val Asp Thr Glu Glu Ser Asn Trp Thr Tyr Asp Pro Val Arg Gly Gln 210 215 220 Tyr Phe Trp His Arg Phe Phe Ser His Gln Pro Asp Leu Asn Tyr Asp 225 230 235 240 Asn Pro Ala Val Gln Glu Ala Met Leu Asp Val Leu Arg Phe Trp Leu 245 250 255 Asp Leu Gly Leu Asp Gly Phe Arg Leu Asp Ala Val Pro Tyr Leu Phe 260 265 270 Glu Arg Glu Gly Thr Asn Gly Glu Asn Leu Lys Glu Thr His Asp Phe 275 280 285 Leu Lys Leu Cys Arg Ser Val Ile Glu Lys Glu Tyr Pro Gly Arg Ile 290 295 300 Leu Leu Ala Glu Ala Asn Gln Trp Pro Gln Asp Val Val Glu Tyr Phe 305 310 315 320 Gly Glu Lys Asp Lys Gly Asp Glu Cys His Met Ala Phe His 325 330 <210> 25 <211> 1386 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1363) <223> RXA00534 <400> 25 ctgtgcagaa agaaaacact cctctggcta ggtagacaca gtttataaag gtagagttga 60 gcgggtaact gtcagcacgt agatcgaaag gtgcacaaag gtg gcc ctg gtc gta 115 Val Ala Leu Val Val 1 5 cag aaa tat ggc ggt tcc tcg ctt gag agt gcg gaa cgc att aga aac 163 Gln Lys Tyr Gly Gly Ser Ser Leu Glu Ser Ala Glu Arg Ile Arg Asn 10 15 20 gtc gct gaa cgg atc gtt gcc acc aag aag gct gga aat gat gtc gtg 211 Val Ala Glu Arg Ile Val Ala Thr Lys Lys Ala Gly Asn Asp Val Val 25 30 35 gtt gtc tgc tcc gca atg gga gac acc acg gat gaa ctt cta gaa ctt 259 Val Val Cys Ser Ala Met Gly Asp Thr Thr Asp Glu Leu Leu Glu Leu 40 45 50 gca gcg gca gtg aat ccc gtt ccg cca gct cgt gaa atg gat atg ctc 307 Ala Ala Ala Val Asn Pro Val Pro Pro Ala Arg Glu Met Asp Met Leu 55 60 65 ctg act gct ggt gag cgt att tct aac gct ctc gtc gcc atg gct att 355 Leu Thr Ala Gly Glu Arg Ile Ser Asn Ala Leu Val Ala Met Ala Ile 70 75 80 85 gag tcc ctt ggc gca gaa gcc caa tct ttc acg ggc tct cag gct ggt 403 Glu Ser Leu Gly Ala Glu Ala Gln Ser Phe Thr Gly Ser Gln Ala Gly 90 95 100 gtg ctc acc acc gag cgc cac gga aac gca cgc att gtt gat gtc act 451 Val Leu Thr Thr Glu Arg His Gly Asn Ala Arg Ile Val Asp Val Thr 105 110 115 cca ggt cgt gtg cgt gaa gca ctc gat gag ggc aag atc tgc att gtt 499 Pro Gly Arg Val Arg Glu Ala Leu Asp Glu Gly Lys Ile Cys Ile Val 120 125 130 gct ggt ttc cag ggt gtt aat aaa gaa acc cgc gat gtc acc acg ttg 547 Ala Gly Phe Gln Gly Val Asn Lys Glu Thr Arg Asp Val Thr Thr Leu 135 140 145 ggt cgt ggt ggt tct gac acc act gca gtt gcg ttg gca gct gct ttg 595 Gly Arg Gly Gly Ser Asp Thr Thr Ala Val Ala Leu Ala Ala Ala Leu 150 155 160 165 aac gct gat gtg tgt gag att tac tcg gac gtt gac ggt gtg tat acc 643 Asn Ala Asp Val Cys Glu Ile Tyr Ser Asp Val Asp Gly Val Tyr Thr 170 175 180 gct gac ccg cgc atc gtt cct aat gca cag aag ctg gaa aag ctc agc 691 Ala Asp Pro Arg Ile Val Pro Asn Ala Gln Lys Leu Glu Lys Leu Ser 185 190 195 ttc gaa gaa atg ctg gaa ctt gct gct gtt ggc tcc aag att ttg gtg 739 Phe Glu Glu Met Leu Glu Leu Ala Ala Val Gly Ser Lys Ile Leu Val 200 205 210 ctg cgc agt gtt gaa tac gct cgt gca ttc aat gtg cca ctt cgc gta 787 Leu Arg Ser Val Glu Tyr Ala Arg Ala Phe Asn Val Pro Leu Arg Val 215 220 225 cgc tcg tct tat agt aat gat ccc ggc act ttg att gcc ggc tct atg 835 Arg Ser Ser Tyr Ser Asn Asp Pro Gly Thr Leu Ile Ala Gly Ser Met 230 235 240 245 gag gat att cct gtg gaa gaa gca gtc ctt acc ggt gtc gca acc gac 883 Glu Asp Ile Pro Val Glu Glu Ala Val Leu Thr Gly Val Ala Thr Asp 250 255 260 aag tcc gaa gcc aaa gta acc gtt ctg ggt att tcc gat aag cca ggc 931 Lys Ser Glu Ala Lys Val Thr Val Leu Gly Ile Ser Asp Lys Pro Gly 265 270 275 gag gct gcg aag gtt ttc cgt gcg ttg gct gat gca gaa atc aac att 979 Glu Ala Ala Lys Val Phe Arg Ala Leu Ala Asp Ala Glu Ile Asn Ile 280 285 290 gac atg gtt ctg cag aac gtc tct tct gta gaa gac ggc acc acc gac 1027 Asp Met Val Leu Gln Asn Val Ser Ser Val Glu Asp Gly Thr Thr Asp 295 300 305 atc acc ttc acc tgc cct cgt tcc gac ggc cgc cgc gcg atg gag atc 1075 Ile Thr Phe Thr Cys Pro Arg Ser Asp Gly Arg Arg Ala Met Glu Ile 310 315 320 325 ttg aag aag ctt cag gtt cag ggc aac tgg acc aat gtg ctt tac gac 1123 Leu Lys Lys Leu Gln Val Gln Gly Asn Trp Thr Asn Val Leu Tyr Asp 330 335 340 gac cag gtc ggc aaa gtc tcc ctc gtg ggt gct ggc atg aag tct cac 1171 Asp Gln Val Gly Lys Val Ser Leu Val Gly Ala Gly Met Lys Ser His 345 350 355 cca ggt gtt acc gca gag ttc atg gaa gct ctg cgc gat gtc aac gtg 1219 Pro Gly Val Thr Ala Glu Phe Met Glu Ala Leu Arg Asp Val Asn Val 360 365 370 aac atc gaa ttg att tcc acc tct gag att cgt att tcc gtg ctg atc 1267 Asn Ile Glu Leu Ile Ser Thr Ser Glu Ile Arg Ile Ser Val Leu Ile 375 380 385 cgt gaa gat gat ctg gat gct gct gca cgt gca ttg cat gag cag ttc 1315 Arg Glu Asp Asp Leu Asp Ala Ala Ala Arg Ala Leu His Glu Gln Phe 390 395 400 405 cag ctg ggc ggc gaa gac gaa gcc gtc gtt tat gca ggc acc gga cgc 1363 Gln Leu Gly Gly Glu Asp Glu Ala Val Val Tyr Ala Gly Thr Gly Arg 410 415 420 taaagtttta aaggagtagt ttt 1386 <210> 26 <211> 421 <212> PRT <213> Corynebacterium glutamicum <400> 26 Val Ala Leu Val Val Gln Lys Tyr Gly Gly Ser Ser Leu Glu Ser Ala 1 5 10 15 Glu Arg Ile Arg Asn Val Ala Glu Arg Ile Val Ala Thr Lys Lys Ala 20 25 30 Gly Asn Asp Val Val Val Val Cys Ser Ala Met Gly Asp Thr Thr Asp 35 40 45 Glu Leu Leu Glu Leu Ala Ala Ala Val Asn Pro Val Pro Pro Ala Arg 50 55 60 Glu Met Asp Met Leu Leu Thr Ala Gly Glu Arg Ile Ser Asn Ala Leu 65 70 75 80 Val Ala Met Ala Ile Glu Ser Leu Gly Ala Glu Ala Gln Ser Phe Thr 85 90 95 Gly Ser Gln Ala Gly Val Leu Thr Thr Glu Arg His Gly Asn Ala Arg 100 105 110 Ile Val Asp Val Thr Pro Gly Arg Val Arg Glu Ala Leu Asp Glu Gly 115 120 125 Lys Ile Cys Ile Val Ala Gly Phe Gln Gly Val Asn Lys Glu Thr Arg 130 135 140 Asp Val Thr Thr Leu Gly Arg Gly Gly Ser Asp Thr Thr Ala Val Ala 145 150 155 160 Leu Ala Ala Ala Leu Asn Ala Asp Val Cys Glu Ile Tyr Ser Asp Val 165 170 175 Asp Gly Val Tyr Thr Ala Asp Pro Arg Ile Val Pro Asn Ala Gln Lys 180 185 190 Leu Glu Lys Leu Ser Phe Glu Glu Met Leu Glu Leu Ala Ala Val Gly 195 200 205 Ser Lys Ile Leu Val Leu Arg Ser Val Glu Tyr Ala Arg Ala Phe Asn 210 215 220 Val Pro Leu Arg Val Arg Ser Ser Tyr Ser Asn Asp Pro Gly Thr Leu 225 230 235 240 Ile Ala Gly Ser Met Glu Asp Ile Pro Val Glu Glu Ala Val Leu Thr 245 250 255 Gly Val Ala Thr Asp Lys Ser Glu Ala Lys Val Thr Val Leu Gly Ile 260 265 270 Ser Asp Lys Pro Gly Glu Ala Ala Lys Val Phe Arg Ala Leu Ala Asp 275 280 285 Ala Glu Ile Asn Ile Asp Met Val Leu Gln Asn Val Ser Ser Val Glu 290 295 300 Asp Gly Thr Thr Asp Ile Thr Phe Thr Cys Pro Arg Ser Asp Gly Arg 305 310 315 320 Arg Ala Met Glu Ile Leu Lys Lys Leu Gln Val Gln Gly Asn Trp Thr 325 330 335 Asn Val Leu Tyr Asp Asp Gln Val Gly Lys Val Ser Leu Val Gly Ala 340 345 350 Gly Met Lys Ser His Pro Gly Val Thr Ala Glu Phe Met Glu Ala Leu 355 360 365 Arg Asp Val Asn Val Asn Ile Glu Leu Ile Ser Thr Ser Glu Ile Arg 370 375 380 Ile Ser Val Leu Ile Arg Glu Asp Asp Leu Asp Ala Ala Ala Arg Ala 385 390 395 400 Leu His Glu Gln Phe Gln Leu Gly Gly Glu Asp Glu Ala Val Val Tyr 405 410 415 Ala Gly Thr Gly Arg 420 <210> 27 <211> 1155 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1132) <223> RXA00533 <400> 27 ctgcacgtgc attgcatgag cagttccagc tgggcggcga agacgaagcc gtcgtttatg 60 caggcaccgg acgctaaagt tttaaaggag tagttttaca atg acc acc atc gca 115 Met Thr Thr Ile Ala 1 5 gtt gtt ggt gca acc ggc cag gtc ggc cag gtt atg cgc acc ctt ttg 163 Val Val Gly Ala Thr Gly Gln Val Gly Gln Val Met Arg Thr Leu Leu 10 15 20 gaa gag cgc aat ttc cca gct gac act gtt cgt ttc ttt gct tcc cca 211 Glu Glu Arg Asn Phe Pro Ala Asp Thr Val Arg Phe Phe Ala Ser Pro 25 30 35 cgt tcc gca ggc cgt aag att gaa ttc cgt ggc acg gaa atc gag gta 259 Arg Ser Ala Gly Arg Lys Ile Glu Phe Arg Gly Thr Glu Ile Glu Val 40 45 50 gaa gac att act cag gca acc gag gag tcc ctc aag gac atc gac gtt 307 Glu Asp Ile Thr Gln Ala Thr Glu Glu Ser Leu Lys Asp Ile Asp Val 55 60 65 gcg ttg ttc tcc gct gga ggc acc gct tcc aag cag tac gct cca ctg 355 Ala Leu Phe Ser Ala Gly Gly Thr Ala Ser Lys Gln Tyr Ala Pro Leu 70 75 80 85 ttc gct gct gca ggc gcg act gtt gtg gat aac tct tct gct tgg cgc 403 Phe Ala Ala Ala Gly Ala Thr Val Val Asp Asn Ser Ser Ala Trp Arg 90 95 100 aag gac gac gag gtt cca cta atc gtc tct gag gtg aac cct tcc gac 451 Lys Asp Asp Glu Val Pro Leu Ile Val Ser Glu Val Asn Pro Ser Asp 105 110 115 aag gat tcc ctg gtc aag ggc att att gcg aac cct aac tgc acc acc 499 Lys Asp Ser Leu Val Lys Gly Ile Ile Ala Asn Pro Asn Cys Thr Thr 120 125 130 atg gct gcg atg cca gtg ctg aag cca ctt cac gat gcc gct ggt ctt 547 Met Ala Ala Met Pro Val Leu Lys Pro Leu His Asp Ala Ala Gly Leu 135 140 145 gta aag ctt cac gtt tcc tct tac cag gct gtt tcc ggt tct ggt ctt 595 Val Lys Leu His Val Ser Ser Tyr Gln Ala Val Ser Gly Ser Gly Leu 150 155 160 165 gca ggt gtg gaa acc ttg gca aag cag gtt gct gca gtt gga gac cac 643 Ala Gly Val Glu Thr Leu Ala Lys Gln Val Ala Ala Val Gly Asp His 170 175 180 aac gtt gag ttc gtc cat gat gga cag gct gct gac gca ggc gat gtc 691 Asn Val Glu Phe Val His Asp Gly Gln Ala Ala Asp Ala Gly Asp Val 185 190 195 gga cct tat gtt tca cca atc gct tac aac gtg ctg cca ttc gcc gga 739 Gly Pro Tyr Val Ser Pro Ile Ala Tyr Asn Val Leu Pro Phe Ala Gly 200 205 210 aac ctc gtc gat gac ggc acc ttc gaa acc gat gaa gag cag aag ctg 787 Asn Leu Val Asp Asp Gly Thr Phe Glu Thr Asp Glu Glu Gln Lys Leu 215 220 225 cgc aac gaa tcc cgc aag att ctc ggt ctc cca gac ctc aag gtc tca 835 Arg Asn Glu Ser Arg Lys Ile Leu Gly Leu Pro Asp Leu Lys Val Ser 230 235 240 245 ggc acc tgc gtc cgc gtg ccg gtt ttc acc ggc cac acg ctg acc att 883 Gly Thr Cys Val Arg Val Pro Val Phe Thr Gly His Thr Leu Thr Ile 250 255 260 cac gcc gaa ttc gac aag gca atc acc gtg gac cag gcg cag gag atc 931 His Ala Glu Phe Asp Lys Ala Ile Thr Val Asp Gln Ala Gln Glu Ile 265 270 275 ttg ggt gcc gct tca ggc gtc aag ctt gtc gac gtc cca acc cca ctt 979 Leu Gly Ala Ala Ser Gly Val Lys Leu Val Asp Val Pro Thr Pro Leu 280 285 290 gca gct gcc ggc att gac gaa tcc ctc gtt gga cgc atc cgt cag gac 1027 Ala Ala Ala Gly Ile Asp Glu Ser Leu Val Gly Arg Ile Arg Gln Asp 295 300 305 tcc act gtc gac gat aac cgc ggt ctg gtt ctc gtc gta tct ggc gac 1075 Ser Thr Val Asp Asp Asn Arg Gly Leu Val Leu Val Val Ser Gly Asp 310 315 320 325 aac ctc cgc aag ggt gct gcg cta aac acc atc cag atc gct gag ctg 1123 Asn Leu Arg Lys Gly Ala Ala Leu Asn Thr Ile Gln Ile Ala Glu Leu 330 335 340 ctg gtt aag taaaaacccg ccattaaaaa ctc 1155 Leu Val Lys <210> 28 <211> 344 <212> PRT <213> Corynebacterium glutamicum <400> 28 Met Thr Thr Ile Ala Val Val Gly Ala Thr Gly Gln Val Gly Gln Val 1 5 10 15 Met Arg Thr Leu Leu Glu Glu Arg Asn Phe Pro Ala Asp Thr Val Arg 20 25 30 Phe Phe Ala Ser Pro Arg Ser Ala Gly Arg Lys Ile Glu Phe Arg Gly 35 40 45 Thr Glu Ile Glu Val Glu Asp Ile Thr Gln Ala Thr Glu Glu Ser Leu 50 55 60 Lys Asp Ile Asp Val Ala Leu Phe Ser Ala Gly Gly Thr Ala Ser Lys 65 70 75 80 Gln Tyr Ala Pro Leu Phe Ala Ala Ala Gly Ala Thr Val Val Asp Asn 85 90 95 Ser Ser Ala Trp Arg Lys Asp Asp Glu Val Pro Leu Ile Val Ser Glu 100 105 110 Val Asn Pro Ser Asp Lys Asp Ser Leu Val Lys Gly Ile Ile Ala Asn 115 120 125 Pro Asn Cys Thr Thr Met Ala Ala Met Pro Val Leu Lys Pro Leu His 130 135 140 Asp Ala Ala Gly Leu Val Lys Leu His Val Ser Ser Tyr Gln Ala Val 145 150 155 160 Ser Gly Ser Gly Leu Ala Gly Val Glu Thr Leu Ala Lys Gln Val Ala 165 170 175 Ala Val Gly Asp His Asn Val Glu Phe Val His Asp Gly Gln Ala Ala 180 185 190 Asp Ala Gly Asp Val Gly Pro Tyr Val Ser Pro Ile Ala Tyr Asn Val 195 200 205 Leu Pro Phe Ala Gly Asn Leu Val Asp Asp Gly Thr Phe Glu Thr Asp 210 215 220 Glu Glu Gln Lys Leu Arg Asn Glu Ser Arg Lys Ile Leu Gly Leu Pro 225 230 235 240 Asp Leu Lys Val Ser Gly Thr Cys Val Arg Val Pro Val Phe Thr Gly 245 250 255 His Thr Leu Thr Ile His Ala Glu Phe Asp Lys Ala Ile Thr Val Asp 260 265 270 Gln Ala Gln Glu Ile Leu Gly Ala Ala Ser Gly Val Lys Leu Val Asp 275 280 285 Val Pro Thr Pro Leu Ala Ala Ala Gly Ile Asp Glu Ser Leu Val Gly 290 295 300 Arg Ile Arg Gln Asp Ser Thr Val Asp Asp Asn Arg Gly Leu Val Leu 305 310 315 320 Val Val Ser Gly Asp Asn Leu Arg Lys Gly Ala Ala Leu Asn Thr Ile 325 330 335 Gln Ile Ala Glu Leu Leu Val Lys 340 <210> 29 <211> 608 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (69)..(608) <223> RXA02843 <400> 29 cccattgcgc ggaggtcgca ccccttccga cttgaactga taggccgata gaaattattc 60 tggacgtc atg act act gct tcc gca acc gga att gca aca ctg acc tcc 110 Met Thr Thr Ala Ser Ala Thr Gly Ile Ala Thr Leu Thr Ser 1 5 10 acc ggc gac gtc ctg gac gtg tgg tat cca gaa atc ggg tcc acc gac 158 Thr Gly Asp Val Leu Asp Val Trp Tyr Pro Glu Ile Gly Ser Thr Asp 15 20 25 30 cag tcc gcg ctc aca cct cta gaa ggc gtc gat gaa gat cga aac gtc 206 Gln Ser Ala Leu Thr Pro Leu Glu Gly Val Asp Glu Asp Arg Asn Val 35 40 45 acc cgc aaa atc gtg acg aca act atc gac acc gac gca gcc ccc acc 254 Thr Arg Lys Ile Val Thr Thr Thr Ile Asp Thr Asp Ala Ala Pro Thr 50 55 60 gac acc tac gat gca tgg ctg cgc ctt cac ctc ctc tcc cac cgc gtt 302 Asp Thr Tyr Asp Ala Trp Leu Arg Leu His Leu Leu Ser His Arg Val 65 70 75 ttc cgc cct cac acc atc aac cta gac ggc att ttc ggc ctc ctc aac 350 Phe Arg Pro His Thr Ile Asn Leu Asp Gly Ile Phe Gly Leu Leu Asn 80 85 90 aat gtc gtg tgg acc aac ttc gga ccg tgc gca gtt gac ggt ttc gca 398 Asn Val Val Trp Thr Asn Phe Gly Pro Cys Ala Val Asp Gly Phe Ala 95 100 105 110 ctc acc cgc gcg cgc ctg tca cgc cga ggc caa gtt acg gtt tat agc 446 Leu Thr Arg Ala Arg Leu Ser Arg Arg Gly Gln Val Thr Val Tyr Ser 115 120 125 gtc gac aag ttc cca cgc atg gtc gac tat gtg gtt ccc tcg ggc gtg 494 Val Asp Lys Phe Pro Arg Met Val Asp Tyr Val Val Pro Ser Gly Val 130 135 140 cgc atc ggt gac gcc gac cgc gtc cga ctt ggc gcg tac ctg gca gat 542 Arg Ile Gly Asp Ala Asp Arg Val Arg Leu Gly Ala Tyr Leu Ala Asp 145 150 155 ggc acc acc gtg atg cat gag ggc ttc gtg aac ttc aac gct ggc acg 590 Gly Thr Thr Val Met His Glu Gly Phe Val Asn Phe Asn Ala Gly Thr 160 165 170 ctc ggc gct tcc atg gtt 608 Leu Gly Ala Ser Met Val 175 180 <210> 30 <211> 180 <212> PRT <213> Corynebacterium glutamicum <400> 30 Met Thr Thr Ala Ser Ala Thr Gly Ile Ala Thr Leu Thr Ser Thr Gly 1 5 10 15 Asp Val Leu Asp Val Trp Tyr Pro Glu Ile Gly Ser Thr Asp Gln Ser 20 25 30 Ala Leu Thr Pro Leu Glu Gly Val Asp Glu Asp Arg Asn Val Thr Arg 35 40 45 Lys Ile Val Thr Thr Thr Ile Asp Thr Asp Ala Ala Pro Thr Asp Thr 50 55 60 Tyr Asp Ala Trp Leu Arg Leu His Leu Leu Ser His Arg Val Phe Arg 65 70 75 80 Pro His Thr Ile Asn Leu Asp Gly Ile Phe Gly Leu Leu Asn Asn Val 85 90 95 Val Trp Thr Asn Phe Gly Pro Cys Ala Val Asp Gly Phe Ala Leu Thr 100 105 110 Arg Ala Arg Leu Ser Arg Arg Gly Gln Val Thr Val Tyr Ser Val Asp 115 120 125 Lys Phe Pro Arg Met Val Asp Tyr Val Val Pro Ser Gly Val Arg Ile 130 135 140 Gly Asp Ala Asp Arg Val Arg Leu Gly Ala Tyr Leu Ala Asp Gly Thr 145 150 155 160 Thr Val Met His Glu Gly Phe Val Asn Phe Asn Ala Gly Thr Leu Gly 165 170 175 Ala Ser Met Val 180 <210> 31 <211> 1230 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1207) <223> RXA02022 <400> 31 tatttgcgat tccaactgct tgggctccgc gaatgttttc actcattttt taatcgaccg 60 cttccatcat gttttaacta aggtttgtag gcttaaacct gtg aac tct gaa ctc 115 Val Asn Ser Glu Leu 1 5 aaa cca gga tta gat ctc ctc ggc gac cca att gtc ctt act caa cgt 163 Lys Pro Gly Leu Asp Leu Leu Gly Asp Pro Ile Val Leu Thr Gln Arg 10 15 20 ttg gta gat ata ccg agt ccg tcg ggt cag gaa aag cag att gct gat 211 Leu Val Asp Ile Pro Ser Pro Ser Gly Gln Glu Lys Gln Ile Ala Asp 25 30 35 gaa att gaa gat gcc ctt cgg aac ctt aat cta cct ggt gta gag gtc 259 Glu Ile Glu Asp Ala Leu Arg Asn Leu Asn Leu Pro Gly Val Glu Val 40 45 50 ttc cgc ttc aac aac aac gtt ctt gct cgc acg aac agg gga ttg gcc 307 Phe Arg Phe Asn Asn Asn Val Leu Ala Arg Thr Asn Arg Gly Leu Ala 55 60 65 tcg agg gtc atg ctt gct ggt cat atc gat aca gtg ccg atc gcg gac 355 Ser Arg Val Met Leu Ala Gly His Ile Asp Thr Val Pro Ile Ala Asp 70 75 80 85 aat ctg cca agc cgt gtg gaa gac ggc atc atg tat ggc tgt ggc acc 403 Asn Leu Pro Ser Arg Val Glu Asp Gly Ile Met Tyr Gly Cys Gly Thr 90 95 100 gtc gat atg aaa tct ggg ttg gcg gtg tat ttg cat act ttt gcc acc 451 Val Asp Met Lys Ser Gly Leu Ala Val Tyr Leu His Thr Phe Ala Thr 105 110 115 ttg gcc acg tcg act gag ctt aaa cat gat ctg acg ctg att gcg tat 499 Leu Ala Thr Ser Thr Glu Leu Lys His Asp Leu Thr Leu Ile Ala Tyr 120 125 130 gag tgc gag gaa gtt gct gat cac ctc aat ggt ttg ggc cac att cgc 547 Glu Cys Glu Glu Val Ala Asp His Leu Asn Gly Leu Gly His Ile Arg 135 140 145 gat gag cat ccg gag tgg ttg gcg gct gat ttg gcg ttg ttg ggt gag 595 Asp Glu His Pro Glu Trp Leu Ala Ala Asp Leu Ala Leu Leu Gly Glu 150 155 160 165 cct act ggc ggc tgg att gag gcg ggc tgc cag ggc aat ctg cgc atc 643 Pro Thr Gly Gly Trp Ile Glu Ala Gly Cys Gln Gly Asn Leu Arg Ile 170 175 180 aag gtg acg gcg cat ggt gtg cgt gcc cat tcg gcg aga agc tgg ttg 691 Lys Val Thr Ala His Gly Val Arg Ala His Ser Ala Arg Ser Trp Leu 185 190 195 ggt gat aat gcg atg cat aag ttg tcg ccg atc att tcg aag gtt gct 739 Gly Asp Asn Ala Met His Lys Leu Ser Pro Ile Ile Ser Lys Val Ala 200 205 210 gcg tat aag gcc gca gaa gtc aac att gat ggc ttg acc tac cgt gaa 787 Ala Tyr Lys Ala Ala Glu Val Asn Ile Asp Gly Leu Thr Tyr Arg Glu 215 220 225 ggc ctc aac atc gtt ttc tgc gaa tcg ggc gtg gca aac aac gtc att 835 Gly Leu Asn Ile Val Phe Cys Glu Ser Gly Val Ala Asn Asn Val Ile 230 235 240 245 cca gac ctc gcg tgg atg aac ctc aac ttc cgt ttc gcg ccg aat cgc 883 Pro Asp Leu Ala Trp Met Asn Leu Asn Phe Arg Phe Ala Pro Asn Arg 250 255 260 gat ctc aac gag gcg atc gag cat gtc gtc gaa acg ctt gag ctt gac 931 Asp Leu Asn Glu Ala Ile Glu His Val Val Glu Thr Leu Glu Leu Asp 265 270 275 ggt caa gac ggc atc gaa tgg gcc gta gaa gac ggg gca ggc ggt gcc 979 Gly Gln Asp Gly Ile Glu Trp Ala Val Glu Asp Gly Ala Gly Gly Ala 280 285 290 ctt cca ggc ttg ggg cag cag gtg aca agc ggg ctt atc gac gcc gtc 1027 Leu Pro Gly Leu Gly Gln Gln Val Thr Ser Gly Leu Ile Asp Ala Val 295 300 305 ggc cgc gaa aaa atc cgc gca aaa ttc ggc tgg acc gat gtc tca cgt 1075 Gly Arg Glu Lys Ile Arg Ala Lys Phe Gly Trp Thr Asp Val Ser Arg 310 315 320 325 ttt tca gcc atg gga att cca gcc cta aac ttt ggc gct ggt gat cca 1123 Phe Ser Ala Met Gly Ile Pro Ala Leu Asn Phe Gly Ala Gly Asp Pro 330 335 340 agt ttc gcg cat aaa cgc gac gag cag tgc cca gtg gag caa atc acg 1171 Ser Phe Ala His Lys Arg Asp Glu Gln Cys Pro Val Glu Gln Ile Thr 345 350 355 gat gtg gca gca att ttg aag cag tac ctg agc gag taaccgcatt 1217 Asp Val Ala Ala Ile Leu Lys Gln Tyr Leu Ser Glu 360 365 cggggttatc gtg 1230 <210> 32 <211> 369 <212> PRT <213> Corynebacterium glutamicum <400> 32 Val Asn Ser Glu Leu Lys Pro Gly Leu Asp Leu Leu Gly Asp Pro Ile 1 5 10 15 Val Leu Thr Gln Arg Leu Val Asp Ile Pro Ser Pro Ser Gly Gln Glu 20 25 30 Lys Gln Ile Ala Asp Glu Ile Glu Asp Ala Leu Arg Asn Leu Asn Leu 35 40 45 Pro Gly Val Glu Val Phe Arg Phe Asn Asn Asn Val Leu Ala Arg Thr 50 55 60 Asn Arg Gly Leu Ala Ser Arg Val Met Leu Ala Gly His Ile Asp Thr 65 70 75 80 Val Pro Ile Ala Asp Asn Leu Pro Ser Arg Val Glu Asp Gly Ile Met 85 90 95 Tyr Gly Cys Gly Thr Val Asp Met Lys Ser Gly Leu Ala Val Tyr Leu 100 105 110 His Thr Phe Ala Thr Leu Ala Thr Ser Thr Glu Leu Lys His Asp Leu 115 120 125 Thr Leu Ile Ala Tyr Glu Cys Glu Glu Val Ala Asp His Leu Asn Gly 130 135 140 Leu Gly His Ile Arg Asp Glu His Pro Glu Trp Leu Ala Ala Asp Leu 145 150 155 160 Ala Leu Leu Gly Glu Pro Thr Gly Gly Trp Ile Glu Ala Gly Cys Gln 165 170 175 Gly Asn Leu Arg Ile Lys Val Thr Ala His Gly Val Arg Ala His Ser 180 185 190 Ala Arg Ser Trp Leu Gly Asp Asn Ala Met His Lys Leu Ser Pro Ile 195 200 205 Ile Ser Lys Val Ala Ala Tyr Lys Ala Ala Glu Val Asn Ile Asp Gly 210 215 220 Leu Thr Tyr Arg Glu Gly Leu Asn Ile Val Phe Cys Glu Ser Gly Val 225 230 235 240 Ala Asn Asn Val Ile Pro Asp Leu Ala Trp Met Asn Leu Asn Phe Arg 245 250 255 Phe Ala Pro Asn Arg Asp Leu Asn Glu Ala Ile Glu His Val Val Glu 260 265 270 Thr Leu Glu Leu Asp Gly Gln Asp Gly Ile Glu Trp Ala Val Glu Asp 275 280 285 Gly Ala Gly Gly Ala Leu Pro Gly Leu Gly Gln Gln Val Thr Ser Gly 290 295 300 Leu Ile Asp Ala Val Gly Arg Glu Lys Ile Arg Ala Lys Phe Gly Trp 305 310 315 320 Thr Asp Val Ser Arg Phe Ser Ala Met Gly Ile Pro Ala Leu Asn Phe 325 330 335 Gly Ala Gly Asp Pro Ser Phe Ala His Lys Arg Asp Glu Gln Cys Pro 340 345 350 Val Glu Gln Ile Thr Asp Val Ala Ala Ile Leu Lys Gln Tyr Leu Ser 355 360 365 Glu <210> 33 <211> 1059 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1036) <223> RXA00044 <400> 33 attacctcag ccttccaagc tgatgatgca ttacttaaaa actgcagaca cttgaaaaac 60 ttctcacccg cactcgttcc ctcaacccac aaggagcacc atg gct tcc gca act 115 Met Ala Ser Ala Thr 1 5 ttc acc ggc gtg atc cca ccc gta atg acc cca ctc cac gcc gac ggc 163 Phe Thr Gly Val Ile Pro Pro Val Met Thr Pro Leu His Ala Asp Gly 10 15 20 agt gtg gat gta gaa agc ctc cgc aag ctc gtt gac cac ctc atc aat 211 Ser Val Asp Val Glu Ser Leu Arg Lys Leu Val Asp His Leu Ile Asn 25 30 35 ggt ggc gtc gac gga ctt ttc gca ctg ggc tcc tca ggc gaa gcg gca 259 Gly Gly Val Asp Gly Leu Phe Ala Leu Gly Ser Ser Gly Glu Ala Ala 40 45 50 ttc ctc acc cgc gcc cag cgc aaa ctc gca ctg acc acc atc atc gag 307 Phe Leu Thr Arg Ala Gln Arg Lys Leu Ala Leu Thr Thr Ile Ile Glu 55 60 65 cac acc gca ggc cgc gtt ccc gta act gct ggt gtc att gaa acc acc 355 His Thr Ala Gly Arg Val Pro Val Thr Ala Gly Val Ile Glu Thr Thr 70 75 80 85 act gct cgc gtg att gag ctc gtg gaa gat gcc ctg gag gct ggt gcc 403 Thr Ala Arg Val Ile Glu Leu Val Glu Asp Ala Leu Glu Ala Gly Ala 90 95 100 gaa ggc ctc gtt gcc act gca cct ttc tac acc cgc acc cac gat gtg 451 Glu Gly Leu Val Ala Thr Ala Pro Phe Tyr Thr Arg Thr His Asp Val 105 110 115 gaa att gaa gaa cac ttc cgc aag atc cac gcc gcc gct cca gag ctt 499 Glu Ile Glu Glu His Phe Arg Lys Ile His Ala Ala Ala Pro Glu Leu 120 125 130 cca ctg ttt gcc tac aac atc cca gtg tcg gtg cac tcc aac ctc aac 547 Pro Leu Phe Ala Tyr Asn Ile Pro Val Ser Val His Ser Asn Leu Asn 135 140 145 cca gtc atg ctt ttg acg ctg gcc aag gat ggc gtt ctt gca ggc acc 595 Pro Val Met Leu Leu Thr Leu Ala Lys Asp Gly Val Leu Ala Gly Thr 150 155 160 165 aag gat tcc agt ggc aat gat ggc gca atc cgc tca ctg atc gaa gct 643 Lys Asp Ser Ser Gly Asn Asp Gly Ala Ile Arg Ser Leu Ile Glu Ala 170 175 180 cgt gat gat gct gga ctc act gag cag ttc aag atc ctc acc ggc agc 691 Arg Asp Asp Ala Gly Leu Thr Glu Gln Phe Lys Ile Leu Thr Gly Ser 185 190 195 gaa acc acc gtt gat ttc gcc tac ctt gcg ggt gcc gat gga gtt gtc 739 Glu Thr Thr Val Asp Phe Ala Tyr Leu Ala Gly Ala Asp Gly Val Val 200 205 210 cca ggc ctg ggc aat gtt gat cct gca gca tac gca gct tta gca aaa 787 Pro Gly Leu Gly Asn Val Asp Pro Ala Ala Tyr Ala Ala Leu Ala Lys 215 220 225 ctc tgc ctc gat gga aag tgg gca gaa gct gct gct ttg cag aag cgc 835 Leu Cys Leu Asp Gly Lys Trp Ala Glu Ala Ala Ala Leu Gln Lys Arg 230 235 240 245 atc aac cac ctc ttc cac atc gtc ttc gtg gga gac acc tcc cat atg 883 Ile Asn His Leu Phe His Ile Val Phe Val Gly Asp Thr Ser His Met 250 255 260 tcc gga tcc agc gct ggt ttg ggc ggt ttc aag aca gca ctc gca cac 931 Ser Gly Ser Ser Ala Gly Leu Gly Gly Phe Lys Thr Ala Leu Ala His 265 270 275 ctt ggc att att gaa tcc aat gcg atg gca gtt cct cac cag agc ctc 979 Leu Gly Ile Ile Glu Ser Asn Ala Met Ala Val Pro His Gln Ser Leu 280 285 290 agc gac gaa gaa act gct cgc att cac gcc att gtt gat gaa ttc ctg 1027 Ser Asp Glu Glu Thr Ala Arg Ile His Ala Ile Val Asp Glu Phe Leu 295 300 305 tac acc gct taaggcccac acctcatgac tga 1059 Tyr Thr Ala 310 <210> 34 <211> 312 <212> PRT <213> Corynebacterium glutamicum <400> 34 Met Ala Ser Ala Thr Phe Thr Gly Val Ile Pro Pro Val Met Thr Pro 1 5 10 15 Leu His Ala Asp Gly Ser Val Asp Val Glu Ser Leu Arg Lys Leu Val 20 25 30 Asp His Leu Ile Asn Gly Gly Val Asp Gly Leu Phe Ala Leu Gly Ser 35 40 45 Ser Gly Glu Ala Ala Phe Leu Thr Arg Ala Gln Arg Lys Leu Ala Leu 50 55 60 Thr Thr Ile Ile Glu His Thr Ala Gly Arg Val Pro Val Thr Ala Gly 65 70 75 80 Val Ile Glu Thr Thr Thr Ala Arg Val Ile Glu Leu Val Glu Asp Ala 85 90 95 Leu Glu Ala Gly Ala Glu Gly Leu Val Ala Thr Ala Pro Phe Tyr Thr 100 105 110 Arg Thr His Asp Val Glu Ile Glu Glu His Phe Arg Lys Ile His Ala 115 120 125 Ala Ala Pro Glu Leu Pro Leu Phe Ala Tyr Asn Ile Pro Val Ser Val 130 135 140 His Ser Asn Leu Asn Pro Val Met Leu Leu Thr Leu Ala Lys Asp Gly 145 150 155 160 Val Leu Ala Gly Thr Lys Asp Ser Ser Gly Asn Asp Gly Ala Ile Arg 165 170 175 Ser Leu Ile Glu Ala Arg Asp Asp Ala Gly Leu Thr Glu Gln Phe Lys 180 185 190 Ile Leu Thr Gly Ser Glu Thr Thr Val Asp Phe Ala Tyr Leu Ala Gly 195 200 205 Ala Asp Gly Val Val Pro Gly Leu Gly Asn Val Asp Pro Ala Ala Tyr 210 215 220 Ala Ala Leu Ala Lys Leu Cys Leu Asp Gly Lys Trp Ala Glu Ala Ala 225 230 235 240 Ala Leu Gln Lys Arg Ile Asn His Leu Phe His Ile Val Phe Val Gly 245 250 255 Asp Thr Ser His Met Ser Gly Ser Ser Ala Gly Leu Gly Gly Phe Lys 260 265 270 Thr Ala Leu Ala His Leu Gly Ile Ile Glu Ser Asn Ala Met Ala Val 275 280 285 Pro His Gln Ser Leu Ser Asp Glu Glu Thr Ala Arg Ile His Ala Ile 290 295 300 Val Asp Glu Phe Leu Tyr Thr Ala 305 310 <210> 35 <211> 867 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(844) <223> RXA00863 <400> 35 aacggtcagt taggtatgga tatcagcacc ttctgaacgg gtacgtctag actggtgggc 60 gtttgaaaaa ctcttcgccc cacgaaaatg aaggagcata atg gga atc aag gtt 115 Met Gly Ile Lys Val 1 5 ggc gtt ctc gga gcc aaa ggc cgt gtt ggt caa act att gtg gca gca 163 Gly Val Leu Gly Ala Lys Gly Arg Val Gly Gln Thr Ile Val Ala Ala 10 15 20 gtc aat gag tcc gac gat ctg gag ctt gtt gca gag atc ggc gtc gac 211 Val Asn Glu Ser Asp Asp Leu Glu Leu Val Ala Glu Ile Gly Val Asp 25 30 35 gat gat ttg agc ctt ctg gta gac aac ggc gct gaa gtt gtc gtt gac 259 Asp Asp Leu Ser Leu Leu Val Asp Asn Gly Ala Glu Val Val Val Asp 40 45 50 ttc acc act cct aac gct gtg atg ggc aac ctg gag ttc tgc atc aac 307 Phe Thr Thr Pro Asn Ala Val Met Gly Asn Leu Glu Phe Cys Ile Asn 55 60 65 aac ggc att tct gcg gtt gtt gga acc acg ggc ttc gat gat gct cgt 355 Asn Gly Ile Ser Ala Val Val Gly Thr Thr Gly Phe Asp Asp Ala Arg 70 75 80 85 ttg gag cag gtt cgc gac tgg ctt gaa gga aaa gac aat gtc ggt gtt 403 Leu Glu Gln Val Arg Asp Trp Leu Glu Gly Lys Asp Asn Val Gly Val 90 95 100 ctg atc gca cct aac ttt gct atc tct gcg gtg ttg acc atg gtc ttt 451 Leu Ile Ala Pro Asn Phe Ala Ile Ser Ala Val Leu Thr Met Val Phe 105 110 115 tcc aag cag gct gcc cgc ttc ttc gaa tca gct gaa gtt att gag ctg 499 Ser Lys Gln Ala Ala Arg Phe Phe Glu Ser Ala Glu Val Ile Glu Leu 120 125 130 cac cac ccc aac aag ctg gat gca cct tca ggc acc gcg atc cac act 547 His His Pro Asn Lys Leu Asp Ala Pro Ser Gly Thr Ala Ile His Thr 135 140 145 gct cag ggc att gct gcg gca cgc aaa gaa gca ggc atg gac gca cag 595 Ala Gln Gly Ile Ala Ala Ala Arg Lys Glu Ala Gly Met Asp Ala Gln 150 155 160 165 cca gat gcg acc gag cag gca ctt gag ggt tcc cgt ggc gca agc gta 643 Pro Asp Ala Thr Glu Gln Ala Leu Glu Gly Ser Arg Gly Ala Ser Val 170 175 180 gat gga atc ccg gtt cat gca gtc cgc atg tcc ggc atg gtt gct cac 691 Asp Gly Ile Pro Val His Ala Val Arg Met Ser Gly Met Val Ala His 185 190 195 gag caa gtt atc ttt ggc acc cag ggt cag acc ttg acc atc aag cag 739 Glu Gln Val Ile Phe Gly Thr Gln Gly Gln Thr Leu Thr Ile Lys Gln 200 205 210 gac tcc tat gat cgc aac tca ttt gca cca ggt gtc ttg gtg ggt gtg 787 Asp Ser Tyr Asp Arg Asn Ser Phe Ala Pro Gly Val Leu Val Gly Val 215 220 225 cgc aac att gca cag cac cca ggc cta gtc gta gga ctt gag cat tac 835 Arg Asn Ile Ala Gln His Pro Gly Leu Val Val Gly Leu Glu His Tyr 230 235 240 245 cta ggc ctg taaaggctca tttcagcagc ggg 867 Leu Gly Leu <210> 36 <211> 248 <212> PRT <213> Corynebacterium glutamicum <400> 36 Met Gly Ile Lys Val Gly Val Leu Gly Ala Lys Gly Arg Val Gly Gln 1 5 10 15 Thr Ile Val Ala Ala Val Asn Glu Ser Asp Asp Leu Glu Leu Val Ala 20 25 30 Glu Ile Gly Val Asp Asp Asp Leu Ser Leu Leu Val Asp Asn Gly Ala 35 40 45 Glu Val Val Val Asp Phe Thr Thr Pro Asn Ala Val Met Gly Asn Leu 50 55 60 Glu Phe Cys Ile Asn Asn Gly Ile Ser Ala Val Val Gly Thr Thr Gly 65 70 75 80 Phe Asp Asp Ala Arg Leu Glu Gln Val Arg Asp Trp Leu Glu Gly Lys 85 90 95 Asp Asn Val Gly Val Leu Ile Ala Pro Asn Phe Ala Ile Ser Ala Val 100 105 110 Leu Thr Met Val Phe Ser Lys Gln Ala Ala Arg Phe Phe Glu Ser Ala 115 120 125 Glu Val Ile Glu Leu His His Pro Asn Lys Leu Asp Ala Pro Ser Gly 130 135 140 Thr Ala Ile His Thr Ala Gln Gly Ile Ala Ala Ala Arg Lys Glu Ala 145 150 155 160 Gly Met Asp Ala Gln Pro Asp Ala Thr Glu Gln Ala Leu Glu Gly Ser 165 170 175 Arg Gly Ala Ser Val Asp Gly Ile Pro Val His Ala Val Arg Met Ser 180 185 190 Gly Met Val Ala His Glu Gln Val Ile Phe Gly Thr Gln Gly Gln Thr 195 200 205 Leu Thr Ile Lys Gln Asp Ser Tyr Asp Arg Asn Ser Phe Ala Pro Gly 210 215 220 Val Leu Val Gly Val Arg Asn Ile Ala Gln His Pro Gly Leu Val Val 225 230 235 240 Gly Leu Glu His Tyr Leu Gly Leu 245 <210> 37 <211> 873 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(850) <223> RXA00864 <400> 37 acagcaccca ggcctagtcg taggacttga gcattaccta ggcctgtaaa ggctcatttc 60 agcagcgggt ggaatttttt aaaaggagcg tttaaaggct gtg gcc gaa caa gtt 115 Val Ala Glu Gln Val 1 5 aaa ttg agc gtg gag ttg ata gcg tgc agt tct ttt act cca ccc gct 163 Lys Leu Ser Val Glu Leu Ile Ala Cys Ser Ser Phe Thr Pro Pro Ala 10 15 20 gat gtt gag tgg tca act gat gtt gag ggc gcg gaa gca ctc gtc gag 211 Asp Val Glu Trp Ser Thr Asp Val Glu Gly Ala Glu Ala Leu Val Glu 25 30 35 ttt gcg ggt cgt gcc tgc tac gaa act ttt gat aag ccg aac cct cga 259 Phe Ala Gly Arg Ala Cys Tyr Glu Thr Phe Asp Lys Pro Asn Pro Arg 40 45 50 act gct tcc aat gct gcg tat ctg cgc cac atc atg gaa gtg ggg cac 307 Thr Ala Ser Asn Ala Ala Tyr Leu Arg His Ile Met Glu Val Gly His 55 60 65 act gct ttg ctt gag cat gcc aat gcc acg atg tat atc cga ggc att 355 Thr Ala Leu Leu Glu His Ala Asn Ala Thr Met Tyr Ile Arg Gly Ile 70 75 80 85 tct cgg tcc gcg acc cat gaa ttg gtc cga cac cgc cat ttt tcc ttc 403 Ser Arg Ser Ala Thr His Glu Leu Val Arg His Arg His Phe Ser Phe 90 95 100 tct caa ctg tct cag cgt ttc gtg cac agc gga gaa tcg gaa gta gtg 451 Ser Gln Leu Ser Gln Arg Phe Val His Ser Gly Glu Ser Glu Val Val 105 110 115 gtg ccc act ctc atc gat gaa gat ccg cag ttg cgt gaa ctt ttc atg 499 Val Pro Thr Leu Ile Asp Glu Asp Pro Gln Leu Arg Glu Leu Phe Met 120 125 130 cac gcc atg gat gag tct cgg ttc gct ttc aat gag ctg ctt aat gcg 547 His Ala Met Asp Glu Ser Arg Phe Ala Phe Asn Glu Leu Leu Asn Ala 135 140 145 ctg gaa gaa aaa ctt ggc gat gaa ccg aat gca ctt tta agg aaa aag 595 Leu Glu Glu Lys Leu Gly Asp Glu Pro Asn Ala Leu Leu Arg Lys Lys 150 155 160 165 cag gct cgt caa gca gct cgc gct gtg ctg ccc aac gct aca gag tcc 643 Gln Ala Arg Gln Ala Ala Arg Ala Val Leu Pro Asn Ala Thr Glu Ser 170 175 180 aga atc gtg gtg tct gga aac ttc cgc acc tgg agg cat ttc att ggc 691 Arg Ile Val Val Ser Gly Asn Phe Arg Thr Trp Arg His Phe Ile Gly 185 190 195 atg cga gcc agt gaa cat gca gac gtc gaa atc cgc gaa gta gcg gta 739 Met Arg Ala Ser Glu His Ala Asp Val Glu Ile Arg Glu Val Ala Val 200 205 210 gaa tgt tta aga aag ctg cag gta gca gcg cca act gtt ttc ggt gat 787 Glu Cys Leu Arg Lys Leu Gln Val Ala Ala Pro Thr Val Phe Gly Asp 215 220 225 ttt gag att gaa act ttg gca gac gga tcg caa atg gca aca agc ccg 835 Phe Glu Ile Glu Thr Leu Ala Asp Gly Ser Gln Met Ala Thr Ser Pro 230 235 240 245 tat gtc atg gac ttt taacgcaaag ctcacaccca cga 873 Tyr Val Met Asp Phe 250 <210> 38 <211> 250 <212> PRT <213> Corynebacterium glutamicum <400> 38 Val Ala Glu Gln Val Lys Leu Ser Val Glu Leu Ile Ala Cys Ser Ser 1 5 10 15 Phe Thr Pro Pro Ala Asp Val Glu Trp Ser Thr Asp Val Glu Gly Ala 20 25 30 Glu Ala Leu Val Glu Phe Ala Gly Arg Ala Cys Tyr Glu Thr Phe Asp 35 40 45 Lys Pro Asn Pro Arg Thr Ala Ser Asn Ala Ala Tyr Leu Arg His Ile 50 55 60 Met Glu Val Gly His Thr Ala Leu Leu Glu His Ala Asn Ala Thr Met 65 70 75 80 Tyr Ile Arg Gly Ile Ser Arg Ser Ala Thr His Glu Leu Val Arg His 85 90 95 Arg His Phe Ser Phe Ser Gln Leu Ser Gln Arg Phe Val His Ser Gly 100 105 110 Glu Ser Glu Val Val Val Pro Thr Leu Ile Asp Glu Asp Pro Gln Leu 115 120 125 Arg Glu Leu Phe Met His Ala Met Asp Glu Ser Arg Phe Ala Phe Asn 130 135 140 Glu Leu Leu Asn Ala Leu Glu Glu Lys Leu Gly Asp Glu Pro Asn Ala 145 150 155 160 Leu Leu Arg Lys Lys Gln Ala Arg Gln Ala Ala Arg Ala Val Leu Pro 165 170 175 Asn Ala Thr Glu Ser Arg Ile Val Val Ser Gly Asn Phe Arg Thr Trp 180 185 190 Arg His Phe Ile Gly Met Arg Ala Ser Glu His Ala Asp Val Glu Ile 195 200 205 Arg Glu Val Ala Val Glu Cys Leu Arg Lys Leu Gln Val Ala Ala Pro 210 215 220 Thr Val Phe Gly Asp Phe Glu Ile Glu Thr Leu Ala Asp Gly Ser Gln 225 230 235 240 Met Ala Thr Ser Pro Tyr Val Met Asp Phe 245 250 <210> 39 <211> 608 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (69)..(608) <223> RXA02843 <400> 39 cccattgcgc ggaggtcgca ccccttccga cttgaactga taggccgata gaaattattc 60 tggacgtc atg act act gct tcc gca acc gga att gca aca ctg acc tcc 110 Met Thr Thr Ala Ser Ala Thr Gly Ile Ala Thr Leu Thr Ser 1 5 10 acc ggc gac gtc ctg gac gtg tgg tat cca gaa atc ggg tcc acc gac 158 Thr Gly Asp Val Leu Asp Val Trp Tyr Pro Glu Ile Gly Ser Thr Asp 15 20 25 30 cag tcc gcg ctc aca cct cta gaa ggc gtc gat gaa gat cga aac gtc 206 Gln Ser Ala Leu Thr Pro Leu Glu Gly Val Asp Glu Asp Arg Asn Val 35 40 45 acc cgc aaa atc gtg acg aca act atc gac acc gac gca gcc ccc acc 254 Thr Arg Lys Ile Val Thr Thr Thr Ile Asp Thr Asp Ala Ala Pro Thr 50 55 60 gac acc tac gat gca tgg ctg cgc ctt cac ctc ctc tcc cac cgc gtt 302 Asp Thr Tyr Asp Ala Trp Leu Arg Leu His Leu Leu Ser His Arg Val 65 70 75 ttc cgc cct cac acc atc aac cta gac ggc att ttc ggc ctc ctc aac 350 Phe Arg Pro His Thr Ile Asn Leu Asp Gly Ile Phe Gly Leu Leu Asn 80 85 90 aat gtc gtg tgg acc aac ttc gga ccg tgc gca gtt gac ggt ttc gca 398 Asn Val Val Trp Thr Asn Phe Gly Pro Cys Ala Val Asp Gly Phe Ala 95 100 105 110 ctc acc cgc gcg cgc ctg tca cgc cga ggc caa gtt acg gtt tat agc 446 Leu Thr Arg Ala Arg Leu Ser Arg Arg Gly Gln Val Thr Val Tyr Ser 115 120 125 gtc gac aag ttc cca cgc atg gtc gac tat gtg gtt ccc tcg ggc gtg 494 Val Asp Lys Phe Pro Arg Met Val Asp Tyr Val Val Pro Ser Gly Val 130 135 140 cgc atc ggt gac gcc gac cgc gtc cga ctt ggc gcg tac ctg gca gat 542 Arg Ile Gly Asp Ala Asp Arg Val Arg Leu Gly Ala Tyr Leu Ala Asp 145 150 155 ggc acc acc gtg atg cat gag ggc ttc gtg aac ttc aac gct ggc acg 590 Gly Thr Thr Val Met His Glu Gly Phe Val Asn Phe Asn Ala Gly Thr 160 165 170 ctc ggc gct tcc atg gtt 608 Leu Gly Ala Ser Met Val 175 180 <210> 40 <211> 180 <212> PRT <213> Corynebacterium glutamicum <400> 40 Met Thr Thr Ala Ser Ala Thr Gly Ile Ala Thr Leu Thr Ser Thr Gly 1 5 10 15 Asp Val Leu Asp Val Trp Tyr Pro Glu Ile Gly Ser Thr Asp Gln Ser 20 25 30 Ala Leu Thr Pro Leu Glu Gly Val Asp Glu Asp Arg Asn Val Thr Arg 35 40 45 Lys Ile Val Thr Thr Thr Ile Asp Thr Asp Ala Ala Pro Thr Asp Thr 50 55 60 Tyr Asp Ala Trp Leu Arg Leu His Leu Leu Ser His Arg Val Phe Arg 65 70 75 80 Pro His Thr Ile Asn Leu Asp Gly Ile Phe Gly Leu Leu Asn Asn Val 85 90 95 Val Trp Thr Asn Phe Gly Pro Cys Ala Val Asp Gly Phe Ala Leu Thr 100 105 110 Arg Ala Arg Leu Ser Arg Arg Gly Gln Val Thr Val Tyr Ser Val Asp 115 120 125 Lys Phe Pro Arg Met Val Asp Tyr Val Val Pro Ser Gly Val Arg Ile 130 135 140 Gly Asp Ala Asp Arg Val Arg Leu Gly Ala Tyr Leu Ala Asp Gly Thr 145 150 155 160 Thr Val Met His Glu Gly Phe Val Asn Phe Asn Ala Gly Thr Leu Gly 165 170 175 Ala Ser Met Val 180 <210> 41 <211> 1143 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1120) <223> RXN00355 <400> 41 aatagatcag cgcatccgtg gtggaaccaa aaggctcaac aatacgaaac gttcgctttc 60 ggtcctgatg aaagagatgt ccctgaatca tcatctaagt atg cat ctc ggt aag 115 Met His Leu Gly Lys 1 5 ctc gac cag gac agt gcc acc aca att ttg gag gat tac aag aac atg 163 Leu Asp Gln Asp Ser Ala Thr Thr Ile Leu Glu Asp Tyr Lys Asn Met 10 15 20 acc aac atc cgc gta gct atc gtg ggc tac gga aac ctg gga cgc agc 211 Thr Asn Ile Arg Val Ala Ile Val Gly Tyr Gly Asn Leu Gly Arg Ser 25 30 35 gtc gaa aag ctt att gcc aag cag ccc gac atg gac ctt gta gga atc 259 Val Glu Lys Leu Ile Ala Lys Gln Pro Asp Met Asp Leu Val Gly Ile 40 45 50 ttc tcg cgc cgg gcc acc ctc gac aca aag acg cca gtc ttt gat gtc 307 Phe Ser Arg Arg Ala Thr Leu Asp Thr Lys Thr Pro Val Phe Asp Val 55 60 65 gcc gac gtg gac aag cac gcc gac gac gtg gac gtg ctg ttc ctg tgc 355 Ala Asp Val Asp Lys His Ala Asp Asp Val Asp Val Leu Phe Leu Cys 70 75 80 85 atg ggc tcc gcc acc gac atc cct gag cag gca cca aag ttc gcg cag 403 Met Gly Ser Ala Thr Asp Ile Pro Glu Gln Ala Pro Lys Phe Ala Gln 90 95 100 ttc gcc tgc acc gta gac acc tac gac aac cac cgc gac atc cca cgc 451 Phe Ala Cys Thr Val Asp Thr Tyr Asp Asn His Arg Asp Ile Pro Arg 105 110 115 cac cgc cag gtc atg aac gaa gcc gcc acc gca gcc ggc aac gtt gca 499 His Arg Gln Val Met Asn Glu Ala Ala Thr Ala Ala Gly Asn Val Ala 120 125 130 ctg gtc tct acc ggc tgg gat cca gga atg ttc tcc atc aac cgc gtc 547 Leu Val Ser Thr Gly Trp Asp Pro Gly Met Phe Ser Ile Asn Arg Val 135 140 145 tac gca gcg gca gtc tta gcc gag cac cag cag cac acc ttc tgg ggc 595 Tyr Ala Ala Ala Val Leu Ala Glu His Gln Gln His Thr Phe Trp Gly 150 155 160 165 cca ggt ttg tca cag ggc cac tcc gat gct ttg cga cgc atc cct ggc 643 Pro Gly Leu Ser Gln Gly His Ser Asp Ala Leu Arg Arg Ile Pro Gly 170 175 180 gtt caa aag gca gtc cag tac acc ctc cca tcc gaa gac gcc ctg gaa 691 Val Gln Lys Ala Val Gln Tyr Thr Leu Pro Ser Glu Asp Ala Leu Glu 185 190 195 aag gcc cgc cgc ggc gaa gcc ggc gac ctt acc gga aag caa acc cac 739 Lys Ala Arg Arg Gly Glu Ala Gly Asp Leu Thr Gly Lys Gln Thr His 200 205 210 aag cgc caa tgc ttc gtg gtt gcc gac gcg gcc gat cac gag cgc atc 787 Lys Arg Gln Cys Phe Val Val Ala Asp Ala Ala Asp His Glu Arg Ile 215 220 225 gaa aac gac atc cgc acc atg cct gat tac ttc gtt ggc tac gaa gtc 835 Glu Asn Asp Ile Arg Thr Met Pro Asp Tyr Phe Val Gly Tyr Glu Val 230 235 240 245 gaa gtc aac ttc atc gac gaa gca acc ttc gac tcc gag cac acc ggc 883 Glu Val Asn Phe Ile Asp Glu Ala Thr Phe Asp Ser Glu His Thr Gly 250 255 260 atg cca cac ggt ggc cac gtg att acc acc ggc gac acc ggt ggc ttc 931 Met Pro His Gly Gly His Val Ile Thr Thr Gly Asp Thr Gly Gly Phe 265 270 275 aac cac acc gtg gaa tac atc ctc aag ctg gac cga aac cca gat ttc 979 Asn His Thr Val Glu Tyr Ile Leu Lys Leu Asp Arg Asn Pro Asp Phe 280 285 290 acc gct tcc tca cag atc gct ttc ggt cgc gca gct cac cgc atg aag 1027 Thr Ala Ser Ser Gln Ile Ala Phe Gly Arg Ala Ala His Arg Met Lys 295 300 305 cag cag ggc caa agc gga gct ttc acc gtc ctc gaa gtt gct cca tac 1075 Gln Gln Gly Gln Ser Gly Ala Phe Thr Val Leu Glu Val Ala Pro Tyr 310 315 320 325 ctg ctc tcc cca gag aac ttg gac gat ctg atc gca cgc gac gtc 1120 Leu Leu Ser Pro Glu Asn Leu Asp Asp Leu Ile Ala Arg Asp Val 330 335 340 taatttagct cgaggggcaa gga 1143 <210> 42 <211> 340 <212> PRT <213> Corynebacterium glutamicum <400> 42 Met His Leu Gly Lys Leu Asp Gln Asp Ser Ala Thr Thr Ile Leu Glu 1 5 10 15 Asp Tyr Lys Asn Met Thr Asn Ile Arg Val Ala Ile Val Gly Tyr Gly 20 25 30 Asn Leu Gly Arg Ser Val Glu Lys Leu Ile Ala Lys Gln Pro Asp Met 35 40 45 Asp Leu Val Gly Ile Phe Ser Arg Arg Ala Thr Leu Asp Thr Lys Thr 50 55 60 Pro Val Phe Asp Val Ala Asp Val Asp Lys His Ala Asp Asp Val Asp 65 70 75 80 Val Leu Phe Leu Cys Met Gly Ser Ala Thr Asp Ile Pro Glu Gln Ala 85 90 95 Pro Lys Phe Ala Gln Phe Ala Cys Thr Val Asp Thr Tyr Asp Asn His 100 105 110 Arg Asp Ile Pro Arg His Arg Gln Val Met Asn Glu Ala Ala Thr Ala 115 120 125 Ala Gly Asn Val Ala Leu Val Ser Thr Gly Trp Asp Pro Gly Met Phe 130 135 140 Ser Ile Asn Arg Val Tyr Ala Ala Ala Val Leu Ala Glu His Gln Gln 145 150 155 160 His Thr Phe Trp Gly Pro Gly Leu Ser Gln Gly His Ser Asp Ala Leu 165 170 175 Arg Arg Ile Pro Gly Val Gln Lys Ala Val Gln Tyr Thr Leu Pro Ser 180 185 190 Glu Asp Ala Leu Glu Lys Ala Arg Arg Gly Glu Ala Gly Asp Leu Thr 195 200 205 Gly Lys Gln Thr His Lys Arg Gln Cys Phe Val Val Ala Asp Ala Ala 210 215 220 Asp His Glu Arg Ile Glu Asn Asp Ile Arg Thr Met Pro Asp Tyr Phe 225 230 235 240 Val Gly Tyr Glu Val Glu Val Asn Phe Ile Asp Glu Ala Thr Phe Asp 245 250 255 Ser Glu His Thr Gly Met Pro His Gly Gly His Val Ile Thr Thr Gly 260 265 270 Asp Thr Gly Gly Phe Asn His Thr Val Glu Tyr Ile Leu Lys Leu Asp 275 280 285 Arg Asn Pro Asp Phe Thr Ala Ser Ser Gln Ile Ala Phe Gly Arg Ala 290 295 300 Ala His Arg Met Lys Gln Gln Gly Gln Ser Gly Ala Phe Thr Val Leu 305 310 315 320 Glu Val Ala Pro Tyr Leu Leu Ser Pro Glu Asn Leu Asp Asp Leu Ile 325 330 335 Ala Arg Asp Val 340 <210> 43 <211> 958 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(958) <223> FRXA00352 <400> 43 aatagatcag cgcatccgtg gtggaaccaa aaggctcaac aatacgaaac gttcgctttc 60 ggtcctgatg aaagagatgt ccctgaatca tcatctaagt atg cat ctc ggt aag 115 Met His Leu Gly Lys 1 5 ctc gac cag gac agt gcc acc aca att ttg gag gat tac aag aac atg 163 Leu Asp Gln Asp Ser Ala Thr Thr Ile Leu Glu Asp Tyr Lys Asn Met 10 15 20 acc aac atc cgc gta gct atc gtg ggc tac gga aac ctg gga cgc agc 211 Thr Asn Ile Arg Val Ala Ile Val Gly Tyr Gly Asn Leu Gly Arg Ser 25 30 35 gtc gaa aag ctt att gcc aag cag ccc gac atg gac ctt gta gga atc 259 Val Glu Lys Leu Ile Ala Lys Gln Pro Asp Met Asp Leu Val Gly Ile 40 45 50 ttc tcg cgc cgg gcc acc ctc gac aca aag acg cca gtc ttt gat gtc 307 Phe Ser Arg Arg Ala Thr Leu Asp Thr Lys Thr Pro Val Phe Asp Val 55 60 65 gcc gac gtg gac aag cac gcc gac gac gtg gac gtg ctg ttc ctg tgc 355 Ala Asp Val Asp Lys His Ala Asp Asp Val Asp Val Leu Phe Leu Cys 70 75 80 85 atg ggc tcc gcc acc gac atc cct gag cag gca cca aag ttc gcg cag 403 Met Gly Ser Ala Thr Asp Ile Pro Glu Gln Ala Pro Lys Phe Ala Gln 90 95 100 ttc gcc tgc acc gta gac acc tac gac aac cac cgc gac atc cca cgc 451 Phe Ala Cys Thr Val Asp Thr Tyr Asp Asn His Arg Asp Ile Pro Arg 105 110 115 cac cgc cag gtc atg aac gaa gcc gcc acc gca gcc ggc aac gtt gca 499 His Arg Gln Val Met Asn Glu Ala Ala Thr Ala Ala Gly Asn Val Ala 120 125 130 ctg gtc tct acc ggc tgg gat cca gga atg ttc tcc atc aac cgc gtc 547 Leu Val Ser Thr Gly Trp Asp Pro Gly Met Phe Ser Ile Asn Arg Val 135 140 145 tac gca gcg gca gtc tta gcc gag cac cag cag cac acc ttc tgg ggc 595 Tyr Ala Ala Ala Val Leu Ala Glu His Gln Gln His Thr Phe Trp Gly 150 155 160 165 cca ggt ttg tca cag ggc cac tcc gat gct ttg cga cgc atc cct ggc 643 Pro Gly Leu Ser Gln Gly His Ser Asp Ala Leu Arg Arg Ile Pro Gly 170 175 180 gtt caa aag gca gtc cag tac acc ctc cca tcc gaa gac gcc ctg gaa 691 Val Gln Lys Ala Val Gln Tyr Thr Leu Pro Ser Glu Asp Ala Leu Glu 185 190 195 aag gcc cgc cgc ggc gaa gcc ggc gac ctt acc gga aag caa acc cac 739 Lys Ala Arg Arg Gly Glu Ala Gly Asp Leu Thr Gly Lys Gln Thr His 200 205 210 aag cgc caa tgc ttc gtg gtt gcc gac gcg gcc gat cac gag cgc atc 787 Lys Arg Gln Cys Phe Val Val Ala Asp Ala Ala Asp His Glu Arg Ile 215 220 225 gaa aac gac atc cgc acc atg cct gat tac ttc gtt ggc tac gaa gtc 835 Glu Asn Asp Ile Arg Thr Met Pro Asp Tyr Phe Val Gly Tyr Glu Val 230 235 240 245 gaa gtc aac ttc atc gac gaa gca acc ttc gac tcc gag cac acc ggc 883 Glu Val Asn Phe Ile Asp Glu Ala Thr Phe Asp Ser Glu His Thr Gly 250 255 260 atg cca cac ggt ggc cac gtg att acc acc ggc gac acc ggt ggc ttc 931 Met Pro His Gly Gly His Val Ile Thr Thr Gly Asp Thr Gly Gly Phe 265 270 275 aac cac acc gtg gaa tac atc ctc aag 958 Asn His Thr Val Glu Tyr Ile Leu Lys 280 285 <210> 44 <211> 286 <212> PRT <213> Corynebacterium glutamicum <400> 44 Met His Leu Gly Lys Leu Asp Gln Asp Ser Ala Thr Thr Ile Leu Glu 1 5 10 15 Asp Tyr Lys Asn Met Thr Asn Ile Arg Val Ala Ile Val Gly Tyr Gly 20 25 30 Asn Leu Gly Arg Ser Val Glu Lys Leu Ile Ala Lys Gln Pro Asp Met 35 40 45 Asp Leu Val Gly Ile Phe Ser Arg Arg Ala Thr Leu Asp Thr Lys Thr 50 55 60 Pro Val Phe Asp Val Ala Asp Val Asp Lys His Ala Asp Asp Val Asp 65 70 75 80 Val Leu Phe Leu Cys Met Gly Ser Ala Thr Asp Ile Pro Glu Gln Ala 85 90 95 Pro Lys Phe Ala Gln Phe Ala Cys Thr Val Asp Thr Tyr Asp Asn His 100 105 110 Arg Asp Ile Pro Arg His Arg Gln Val Met Asn Glu Ala Ala Thr Ala 115 120 125 Ala Gly Asn Val Ala Leu Val Ser Thr Gly Trp Asp Pro Gly Met Phe 130 135 140 Ser Ile Asn Arg Val Tyr Ala Ala Ala Val Leu Ala Glu His Gln Gln 145 150 155 160 His Thr Phe Trp Gly Pro Gly Leu Ser Gln Gly His Ser Asp Ala Leu 165 170 175 Arg Arg Ile Pro Gly Val Gln Lys Ala Val Gln Tyr Thr Leu Pro Ser 180 185 190 Glu Asp Ala Leu Glu Lys Ala Arg Arg Gly Glu Ala Gly Asp Leu Thr 195 200 205 Gly Lys Gln Thr His Lys Arg Gln Cys Phe Val Val Ala Asp Ala Ala 210 215 220 Asp His Glu Arg Ile Glu Asn Asp Ile Arg Thr Met Pro Asp Tyr Phe 225 230 235 240 Val Gly Tyr Glu Val Glu Val Asn Phe Ile Asp Glu Ala Thr Phe Asp 245 250 255 Ser Glu His Thr Gly Met Pro His Gly Gly His Val Ile Thr Thr Gly 260 265 270 Asp Thr Gly Gly Phe Asn His Thr Val Glu Tyr Ile Leu Lys 275 280 285 <210> 45 <211> 1400 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1377) <223> RXA00972 <400> 45 cct gca cct ggt tgg cgt ttc cgc acc gga gaa gat gta aca atg gct 48 Pro Ala Pro Gly Trp Arg Phe Arg Thr Gly Glu Asp Val Thr Met Ala 1 5 10 15 aca gtt gaa aat ttc aat gaa ctt ccc gca cac gta tgg cca cgc aat 96 Thr Val Glu Asn Phe Asn Glu Leu Pro Ala His Val Trp Pro Arg Asn 20 25 30 gcc gtg cgc caa gaa gac ggc gtt gtc acc gtc gct ggt gtg cct ctg 144 Ala Val Arg Gln Glu Asp Gly Val Val Thr Val Ala Gly Val Pro Leu 35 40 45 cct gac ctc gct gaa gaa tac gga acc cca ctg ttc gta gtc gac gag 192 Pro Asp Leu Ala Glu Glu Tyr Gly Thr Pro Leu Phe Val Val Asp Glu 50 55 60 gac gat ttc cgt tcc cgc tgt cgc gac atg gct acc gca ttc ggt gga 240 Asp Asp Phe Arg Ser Arg Cys Arg Asp Met Ala Thr Ala Phe Gly Gly 65 70 75 80 cca ggc aat gtg cac tac gca tct aaa gcg ttc ctg acc aag acc att 288 Pro Gly Asn Val His Tyr Ala Ser Lys Ala Phe Leu Thr Lys Thr Ile 85 90 95 gca cgt tgg gtt gat gaa gag ggg ctg gca ctg gac att gca tcc atc 336 Ala Arg Trp Val Asp Glu Glu Gly Leu Ala Leu Asp Ile Ala Ser Ile 100 105 110 aac gaa ctg ggc att gcc ctg gcc gct ggt ttc ccc gcc agc cgt atc 384 Asn Glu Leu Gly Ile Ala Leu Ala Ala Gly Phe Pro Ala Ser Arg Ile 115 120 125 acc gcg cac ggc aac aac aaa ggc gta gag ttc ctg cgc gcg ttg gtt 432 Thr Ala His Gly Asn Asn Lys Gly Val Glu Phe Leu Arg Ala Leu Val 130 135 140 caa aac ggt gtg gga cac gtg gtg ctg gac tcc gca cag gaa cta gaa 480 Gln Asn Gly Val Gly His Val Val Leu Asp Ser Ala Gln Glu Leu Glu 145 150 155 160 ctg ttg gat tac gtt gcc gct ggt gaa ggc aag att cag gac gtg ttg 528 Leu Leu Asp Tyr Val Ala Ala Gly Glu Gly Lys Ile Gln Asp Val Leu 165 170 175 atc cgc gta aag cca ggc atc gaa gca cac acc cac gag ttc atc gcc 576 Ile Arg Val Lys Pro Gly Ile Glu Ala His Thr His Glu Phe Ile Ala 180 185 190 act agc cac gaa gac cag aag ttc gga ttc tcc ctg gca tcc ggt tcc 624 Thr Ser His Glu Asp Gln Lys Phe Gly Phe Ser Leu Ala Ser Gly Ser 195 200 205 gca ttc gaa gca gca aaa gcc gcc aac aac gca gaa aac ctg aac ctg 672 Ala Phe Glu Ala Ala Lys Ala Ala Asn Asn Ala Glu Asn Leu Asn Leu 210 215 220 gtt ggc ctg cac tgc cac gtt ggt tcc cag gtg ttc gac gcc gaa ggc 720 Val Gly Leu His Cys His Val Gly Ser Gln Val Phe Asp Ala Glu Gly 225 230 235 240 ttc aag ctg gca gca gaa cgc gtg ttg ggc ctg tac tca cag atc cac 768 Phe Lys Leu Ala Ala Glu Arg Val Leu Gly Leu Tyr Ser Gln Ile His 245 250 255 agc gaa ctg ggc gtt gcc ctt cct gaa ctg gat ctc ggt ggc gga tac 816 Ser Glu Leu Gly Val Ala Leu Pro Glu Leu Asp Leu Gly Gly Gly Tyr 260 265 270 ggc att gcc tat acc gca gct gaa gaa cca ctc aac gtc gca gaa gtt 864 Gly Ile Ala Tyr Thr Ala Ala Glu Glu Pro Leu Asn Val Ala Glu Val 275 280 285 gcc tcc gac ctg ctc acc gca gtc gga aaa atg gca gcg gaa cta ggc 912 Ala Ser Asp Leu Leu Thr Ala Val Gly Lys Met Ala Ala Glu Leu Gly 290 295 300 atc gac gca cca acc gtg ctt gtt gag ccc ggc cgc gct atc gca ggc 960 Ile Asp Ala Pro Thr Val Leu Val Glu Pro Gly Arg Ala Ile Ala Gly 305 310 315 320 ccc tcc acc gtg acc atc tac gaa gtc ggc acc acc aaa gac gtc cac 1008 Pro Ser Thr Val Thr Ile Tyr Glu Val Gly Thr Thr Lys Asp Val His 325 330 335 gta gac gac gac aaa acc cgc cgt tac atc gcc gtg gac gga ggc atg 1056 Val Asp Asp Asp Lys Thr Arg Arg Tyr Ile Ala Val Asp Gly Gly Met 340 345 350 tcc gac aac atc cgc cca gca ctc tac ggg tcc gaa tac gac gcc cgc 1104 Ser Asp Asn Ile Arg Pro Ala Leu Tyr Gly Ser Glu Tyr Asp Ala Arg 355 360 365 gta gta tcc cgc ttc gcc gaa gga gac cca gta agc acc cgc atc gtg 1152 Val Val Ser Arg Phe Ala Glu Gly Asp Pro Val Ser Thr Arg Ile Val 370 375 380 ggc tcc cac tgc gaa tcc ggc gat atc ctg atc aac gat gaa atc tac 1200 Gly Ser His Cys Glu Ser Gly Asp Ile Leu Ile Asn Asp Glu Ile Tyr 385 390 395 400 cca tct gac atc acc agc ggc gac ttc ctt gca ctc gca gcc acc ggc 1248 Pro Ser Asp Ile Thr Ser Gly Asp Phe Leu Ala Leu Ala Ala Thr Gly 405 410 415 gca tac tgc tac gcc atg agc tcc cgc tac aac gcc ttc aca cgg ccc 1296 Ala Tyr Cys Tyr Ala Met Ser Ser Arg Tyr Asn Ala Phe Thr Arg Pro 420 425 430 gcc gtc gtg tcc gtc cgc gct ggc agc tcc cgc ctc atg ctg cgc cgc 1344 Ala Val Val Ser Val Arg Ala Gly Ser Ser Arg Leu Met Leu Arg Arg 435 440 445 gaa acg ctc gac gac atc ctc tca cta gag gca taacgctttt cgacgcctga 1397 Glu Thr Leu Asp Asp Ile Leu Ser Leu Glu Ala 450 455 ccc 1400 <210> 46 <211> 459 <212> PRT <213> Corynebacterium glutamicum <400> 46 Pro Ala Pro Gly Trp Arg Phe Arg Thr Gly Glu Asp Val Thr Met Ala 1 5 10 15 Thr Val Glu Asn Phe Asn Glu Leu Pro Ala His Val Trp Pro Arg Asn 20 25 30 Ala Val Arg Gln Glu Asp Gly Val Val Thr Val Ala Gly Val Pro Leu 35 40 45 Pro Asp Leu Ala Glu Glu Tyr Gly Thr Pro Leu Phe Val Val Asp Glu 50 55 60 Asp Asp Phe Arg Ser Arg Cys Arg Asp Met Ala Thr Ala Phe Gly Gly 65 70 75 80 Pro Gly Asn Val His Tyr Ala Ser Lys Ala Phe Leu Thr Lys Thr Ile 85 90 95 Ala Arg Trp Val Asp Glu Glu Gly Leu Ala Leu Asp Ile Ala Ser Ile 100 105 110 Asn Glu Leu Gly Ile Ala Leu Ala Ala Gly Phe Pro Ala Ser Arg Ile 115 120 125 Thr Ala His Gly Asn Asn Lys Gly Val Glu Phe Leu Arg Ala Leu Val 130 135 140 Gln Asn Gly Val Gly His Val Val Leu Asp Ser Ala Gln Glu Leu Glu 145 150 155 160 Leu Leu Asp Tyr Val Ala Ala Gly Glu Gly Lys Ile Gln Asp Val Leu 165 170 175 Ile Arg Val Lys Pro Gly Ile Glu Ala His Thr His Glu Phe Ile Ala 180 185 190 Thr Ser His Glu Asp Gln Lys Phe Gly Phe Ser Leu Ala Ser Gly Ser 195 200 205 Ala Phe Glu Ala Ala Lys Ala Ala Asn Asn Ala Glu Asn Leu Asn Leu 210 215 220 Val Gly Leu His Cys His Val Gly Ser Gln Val Phe Asp Ala Glu Gly 225 230 235 240 Phe Lys Leu Ala Ala Glu Arg Val Leu Gly Leu Tyr Ser Gln Ile His 245 250 255 Ser Glu Leu Gly Val Ala Leu Pro Glu Leu Asp Leu Gly Gly Gly Tyr 260 265 270 Gly Ile Ala Tyr Thr Ala Ala Glu Glu Pro Leu Asn Val Ala Glu Val 275 280 285 Ala Ser Asp Leu Leu Thr Ala Val Gly Lys Met Ala Ala Glu Leu Gly 290 295 300 Ile Asp Ala Pro Thr Val Leu Val Glu Pro Gly Arg Ala Ile Ala Gly 305 310 315 320 Pro Ser Thr Val Thr Ile Tyr Glu Val Gly Thr Thr Lys Asp Val His 325 330 335 Val Asp Asp Asp Lys Thr Arg Arg Tyr Ile Ala Val Asp Gly Gly Met 340 345 350 Ser Asp Asn Ile Arg Pro Ala Leu Tyr Gly Ser Glu Tyr Asp Ala Arg 355 360 365 Val Val Ser Arg Phe Ala Glu Gly Asp Pro Val Ser Thr Arg Ile Val 370 375 380 Gly Ser His Cys Glu Ser Gly Asp Ile Leu Ile Asn Asp Glu Ile Tyr 385 390 395 400 Pro Ser Asp Ile Thr Ser Gly Asp Phe Leu Ala Leu Ala Ala Thr Gly 405 410 415 Ala Tyr Cys Tyr Ala Met Ser Ser Arg Tyr Asn Ala Phe Thr Arg Pro 420 425 430 Ala Val Val Ser Val Arg Ala Gly Ser Ser Arg Leu Met Leu Arg Arg 435 440 445 Glu Thr Leu Asp Asp Ile Leu Ser Leu Glu Ala 450 455 <210> 47 <211> 2121 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2098) <223> RXA02653 <400> 47 agacagagtg ttagtgcgtg gggcagctct cactttcatc gacatcactc gagtatgctc 60 accggccgta ttcattccaa taacccgcac agggaaacta atg ata ccg aag ccc 115 Met Ile Pro Lys Pro 1 5 gac gtg acc gac tta tat tta gag gac ctc tta aat gag ggt tcg gaa 163 Asp Val Thr Asp Leu Tyr Leu Glu Asp Leu Leu Asn Glu Gly Ser Glu 10 15 20 aag att cgg tcc gcc aag gat ctt tcc gaa ctt agg aca gtt cta aaa 211 Lys Ile Arg Ser Ala Lys Asp Leu Ser Glu Leu Arg Thr Val Leu Lys 25 30 35 gag gtt tcc tcc caa att cag gaa cga gct ggg aaa aaa gat gaa gaa 259 Glu Val Ser Ser Gln Ile Gln Glu Arg Ala Gly Lys Lys Asp Glu Glu 40 45 50 tgg gga atg ggg gcc act tgg cgg gag ctg tac ccc agc atc gtg gaa 307 Trp Gly Met Gly Ala Thr Trp Arg Glu Leu Tyr Pro Ser Ile Val Glu 55 60 65 cgc gct tcc tac gaa ggg cgt gac agc cta atc gga ttt gat cac tta 355 Arg Ala Ser Tyr Glu Gly Arg Asp Ser Leu Ile Gly Phe Asp His Leu 70 75 80 85 gcc cgg gaa atg gaa aga tta gcc ttc ggc cca cca tcc gaa agt ttt 403 Ala Arg Glu Met Glu Arg Leu Ala Phe Gly Pro Pro Ser Glu Ser Phe 90 95 100 gaa tac ctc caa gaa ctc gta aaa tcc gga gtg gta gac atc act cac 451 Glu Tyr Leu Gln Glu Leu Val Lys Ser Gly Val Val Asp Ile Thr His 105 110 115 ctg cat cgt ggc cgg gaa cca ctg aca gat tta gtt cgt gaa ctt gaa 499 Leu His Arg Gly Arg Glu Pro Leu Thr Asp Leu Val Arg Glu Leu Glu 120 125 130 ata act gtg gtg ata gac gct gtt ctt ccc ccg ccg gga gta gtg cca 547 Ile Thr Val Val Ile Asp Ala Val Leu Pro Pro Pro Gly Val Val Pro 135 140 145 ggc aca ttg gtg cac aat ttg gta aaa gag gga tat gcc aga atg cgt 595 Gly Thr Leu Val His Asn Leu Val Lys Glu Gly Tyr Ala Arg Met Arg 150 155 160 165 cct ggg act cgg ggg tta gat gta gcg gct gac ggc acc gtt caa ggg 643 Pro Gly Thr Arg Gly Leu Asp Val Ala Ala Asp Gly Thr Val Gln Gly 170 175 180 caa cga cat ttg gct gca gtc gga cgg atg acg gaa gat gtg gtt ttg 691 Gln Arg His Leu Ala Ala Val Gly Arg Met Thr Glu Asp Val Val Leu 185 190 195 ggt aat gac aca ttg tcg cga tca tta cat gac ata atc ccg aag tgg 739 Gly Asn Asp Thr Leu Ser Arg Ser Leu His Asp Ile Ile Pro Lys Trp 200 205 210 gct cgt cga gtt atc cgc gac gcg agc acg tat ccc gat agg gta cat 787 Ala Arg Arg Val Ile Arg Asp Ala Ser Thr Tyr Pro Asp Arg Val His 215 220 225 ggt act cca ccg ctt ccg gca cgg ttg gaa ccc tgg gcg gaa aag ctc 835 Gly Thr Pro Pro Leu Pro Ala Arg Leu Glu Pro Trp Ala Glu Lys Leu 230 235 240 245 act tca gat ccg gcc aca tgc cgc cac ctg att gaa gaa ttc ggg agt 883 Thr Ser Asp Pro Ala Thr Cys Arg His Leu Ile Glu Glu Phe Gly Ser 250 255 260 cct gtg aat gta ctc cat tca ggt tct atg cct cgt aat ata aat gag 931 Pro Val Asn Val Leu His Ser Gly Ser Met Pro Arg Asn Ile Asn Glu 265 270 275 ttg gtt gac gcc ggc att cag atg ggg gtg gat act cga ata ttt ttt 979 Leu Val Asp Ala Gly Ile Gln Met Gly Val Asp Thr Arg Ile Phe Phe 280 285 290 gcc cgc aaa gcg aat aag ggt ctt acc ttc gtt gat gcc gtt aaa gac 1027 Ala Arg Lys Ala Asn Lys Gly Leu Thr Phe Val Asp Ala Val Lys Asp 295 300 305 acc ggt cat ggt gta gat gta gcc agt gaa cga gag tta tct cag gtg 1075 Thr Gly His Gly Val Asp Val Ala Ser Glu Arg Glu Leu Ser Gln Val 310 315 320 325 ctt aat cgt gga gtc cca gga gag cgg atc att cta tcc gca gct atc 1123 Leu Asn Arg Gly Val Pro Gly Glu Arg Ile Ile Leu Ser Ala Ala Ile 330 335 340 aaa ccg gac aga cta ttg gca tta gcg atc gaa aat ggc gtg atc atc 1171 Lys Pro Asp Arg Leu Leu Ala Leu Ala Ile Glu Asn Gly Val Ile Ile 345 350 355 tct gtg gat tcg cgt gat gaa tta gat cgc att tcg gct ttg gtt ggt 1219 Ser Val Asp Ser Arg Asp Glu Leu Asp Arg Ile Ser Ala Leu Val Gly 360 365 370 gac cgc gtt gca cga gtt gcg cct aga gta gct cca gat cct gca gtc 1267 Asp Arg Val Ala Arg Val Ala Pro Arg Val Ala Pro Asp Pro Ala Val 375 380 385 tta cct cca act aga ttt ggt gag cgt gct gca gac tgg ggt aat cgg 1315 Leu Pro Pro Thr Arg Phe Gly Glu Arg Ala Ala Asp Trp Gly Asn Arg 390 395 400 405 ctt acc gag gtg ata ccc ggc gtg gat att gtg ggt ctt cac gtt cac 1363 Leu Thr Glu Val Ile Pro Gly Val Asp Ile Val Gly Leu His Val His 410 415 420 ctc cat ggc tat gct gca aaa gac cgt gct ctg gct ctg cag gaa tgt 1411 Leu His Gly Tyr Ala Ala Lys Asp Arg Ala Leu Ala Leu Gln Glu Cys 425 430 435 tgc caa ctc gtc gat tct ctc aga gaa tgc ggg cat tcc cca cag ttt 1459 Cys Gln Leu Val Asp Ser Leu Arg Glu Cys Gly His Ser Pro Gln Phe 440 445 450 att gac ctt gga gga ggg gtg cct atg agc tac att gaa tct gag gaa 1507 Ile Asp Leu Gly Gly Gly Val Pro Met Ser Tyr Ile Glu Ser Glu Glu 455 460 465 gat tgg atc cgt tat caa tcc gct aaa tct gcg act tca gcc ggg tat 1555 Asp Trp Ile Arg Tyr Gln Ser Ala Lys Ser Ala Thr Ser Ala Gly Tyr 470 475 480 485 gcc gaa tcc ttt acg tgg aaa gac gat ccg tta tct aat acg tac ccg 1603 Ala Glu Ser Phe Thr Trp Lys Asp Asp Pro Leu Ser Asn Thr Tyr Pro 490 495 500 ttc tat cag acc cca gtg cgc ggt aat tgg ttg aaa gac gtg ctt tct 1651 Phe Tyr Gln Thr Pro Val Arg Gly Asn Trp Leu Lys Asp Val Leu Ser 505 510 515 aag ggg gta gct cag atg ctc att gac cgg gga ttg cgg tta cac ata 1699 Lys Gly Val Ala Gln Met Leu Ile Asp Arg Gly Leu Arg Leu His Ile 520 525 530 gag cct ggt cga agt tta cta gat ggg tgt ggc gtc act ctt gcc gaa 1747 Glu Pro Gly Arg Ser Leu Leu Asp Gly Cys Gly Val Thr Leu Ala Glu 535 540 545 gtt gct ttt gtg aaa acc cga agt gac ggg ttg cct cta gtg gga ctg 1795 Val Ala Phe Val Lys Thr Arg Ser Asp Gly Leu Pro Leu Val Gly Leu 550 555 560 565 gct atg aac cga acg cag tgc cgg act aca tcc gat gat ttt ctc att 1843 Ala Met Asn Arg Thr Gln Cys Arg Thr Thr Ser Asp Asp Phe Leu Ile 570 575 580 gat ccc ctg cat atc act gac ggt gat gta ggc gag gaa atc gaa gca 1891 Asp Pro Leu His Ile Thr Asp Gly Asp Val Gly Glu Glu Ile Glu Ala 585 590 595 tat cta gtg ggt gcc tac tgc atc gaa gat gag ctg att tta cgc cgg 1939 Tyr Leu Val Gly Ala Tyr Cys Ile Glu Asp Glu Leu Ile Leu Arg Arg 600 605 610 cga atc cgc ttc ccg aga gga gtc aaa cca gga gat atc atc gga att 1987 Arg Ile Arg Phe Pro Arg Gly Val Lys Pro Gly Asp Ile Ile Gly Ile 615 620 625 cct aac acc gca gga tac ttc atg cat atc ttg gaa agt gca tcg cac 2035 Pro Asn Thr Ala Gly Tyr Phe Met His Ile Leu Glu Ser Ala Ser His 630 635 640 645 caa atc ccg ttg gcg aaa aat gta gtg tgg ccg gag ggg cag tta gac 2083 Gln Ile Pro Leu Ala Lys Asn Val Val Trp Pro Glu Gly Gln Leu Asp 650 655 660 gat atc gat gcg gat taagacataa ccattcgcta atc 2121 Asp Ile Asp Ala Asp 665 <210> 48 <211> 666 <212> PRT <213> Corynebacterium glutamicum <400> 48 Met Ile Pro Lys Pro Asp Val Thr Asp Leu Tyr Leu Glu Asp Leu Leu 1 5 10 15 Asn Glu Gly Ser Glu Lys Ile Arg Ser Ala Lys Asp Leu Ser Glu Leu 20 25 30 Arg Thr Val Leu Lys Glu Val Ser Ser Gln Ile Gln Glu Arg Ala Gly 35 40 45 Lys Lys Asp Glu Glu Trp Gly Met Gly Ala Thr Trp Arg Glu Leu Tyr 50 55 60 Pro Ser Ile Val Glu Arg Ala Ser Tyr Glu Gly Arg Asp Ser Leu Ile 65 70 75 80 Gly Phe Asp His Leu Ala Arg Glu Met Glu Arg Leu Ala Phe Gly Pro 85 90 95 Pro Ser Glu Ser Phe Glu Tyr Leu Gln Glu Leu Val Lys Ser Gly Val 100 105 110 Val Asp Ile Thr His Leu His Arg Gly Arg Glu Pro Leu Thr Asp Leu 115 120 125 Val Arg Glu Leu Glu Ile Thr Val Val Ile Asp Ala Val Leu Pro Pro 130 135 140 Pro Gly Val Val Pro Gly Thr Leu Val His Asn Leu Val Lys Glu Gly 145 150 155 160 Tyr Ala Arg Met Arg Pro Gly Thr Arg Gly Leu Asp Val Ala Ala Asp 165 170 175 Gly Thr Val Gln Gly Gln Arg His Leu Ala Ala Val Gly Arg Met Thr 180 185 190 Glu Asp Val Val Leu Gly Asn Asp Thr Leu Ser Arg Ser Leu His Asp 195 200 205 Ile Ile Pro Lys Trp Ala Arg Arg Val Ile Arg Asp Ala Ser Thr Tyr 210 215 220 Pro Asp Arg Val His Gly Thr Pro Pro Leu Pro Ala Arg Leu Glu Pro 225 230 235 240 Trp Ala Glu Lys Leu Thr Ser Asp Pro Ala Thr Cys Arg His Leu Ile 245 250 255 Glu Glu Phe Gly Ser Pro Val Asn Val Leu His Ser Gly Ser Met Pro 260 265 270 Arg Asn Ile Asn Glu Leu Val Asp Ala Gly Ile Gln Met Gly Val Asp 275 280 285 Thr Arg Ile Phe Phe Ala Arg Lys Ala Asn Lys Gly Leu Thr Phe Val 290 295 300 Asp Ala Val Lys Asp Thr Gly His Gly Val Asp Val Ala Ser Glu Arg 305 310 315 320 Glu Leu Ser Gln Val Leu Asn Arg Gly Val Pro Gly Glu Arg Ile Ile 325 330 335 Leu Ser Ala Ala Ile Lys Pro Asp Arg Leu Leu Ala Leu Ala Ile Glu 340 345 350 Asn Gly Val Ile Ile Ser Val Asp Ser Arg Asp Glu Leu Asp Arg Ile 355 360 365 Ser Ala Leu Val Gly Asp Arg Val Ala Arg Val Ala Pro Arg Val Ala 370 375 380 Pro Asp Pro Ala Val Leu Pro Pro Thr Arg Phe Gly Glu Arg Ala Ala 385 390 395 400 Asp Trp Gly Asn Arg Leu Thr Glu Val Ile Pro Gly Val Asp Ile Val 405 410 415 Gly Leu His Val His Leu His Gly Tyr Ala Ala Lys Asp Arg Ala Leu 420 425 430 Ala Leu Gln Glu Cys Cys Gln Leu Val Asp Ser Leu Arg Glu Cys Gly 435 440 445 His Ser Pro Gln Phe Ile Asp Leu Gly Gly Gly Val Pro Met Ser Tyr 450 455 460 Ile Glu Ser Glu Glu Asp Trp Ile Arg Tyr Gln Ser Ala Lys Ser Ala 465 470 475 480 Thr Ser Ala Gly Tyr Ala Glu Ser Phe Thr Trp Lys Asp Asp Pro Leu 485 490 495 Ser Asn Thr Tyr Pro Phe Tyr Gln Thr Pro Val Arg Gly Asn Trp Leu 500 505 510 Lys Asp Val Leu Ser Lys Gly Val Ala Gln Met Leu Ile Asp Arg Gly 515 520 525 Leu Arg Leu His Ile Glu Pro Gly Arg Ser Leu Leu Asp Gly Cys Gly 530 535 540 Val Thr Leu Ala Glu Val Ala Phe Val Lys Thr Arg Ser Asp Gly Leu 545 550 555 560 Pro Leu Val Gly Leu Ala Met Asn Arg Thr Gln Cys Arg Thr Thr Ser 565 570 575 Asp Asp Phe Leu Ile Asp Pro Leu His Ile Thr Asp Gly Asp Val Gly 580 585 590 Glu Glu Ile Glu Ala Tyr Leu Val Gly Ala Tyr Cys Ile Glu Asp Glu 595 600 605 Leu Ile Leu Arg Arg Arg Ile Arg Phe Pro Arg Gly Val Lys Pro Gly 610 615 620 Asp Ile Ile Gly Ile Pro Asn Thr Ala Gly Tyr Phe Met His Ile Leu 625 630 635 640 Glu Ser Ala Ser His Gln Ile Pro Leu Ala Lys Asn Val Val Trp Pro 645 650 655 Glu Gly Gln Leu Asp Asp Ile Asp Ala Asp 660 665 <210> 49 <211> 993 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(970) <223> RXA01393 <400> 49 caaaagcaga cctgtaatga agatttccat gatcaccatc gtgacctatg gaagtactta 60 agtaaaatga ttggttctta acatggttta atatagcttc atg aac ccc att caa 115 Met Asn Pro Ile Gln 1 5 ctg gac act ttg ctc tca atc att gat gaa ggc agc ttc gaa ggc gcc 163 Leu Asp Thr Leu Leu Ser Ile Ile Asp Glu Gly Ser Phe Glu Gly Ala 10 15 20 tcc tta gcc ctt tcc att tcc ccc tcg gcg gtg agt cag cgc gtt aaa 211 Ser Leu Ala Leu Ser Ile Ser Pro Ser Ala Val Ser Gln Arg Val Lys 25 30 35 gct ctc gag cat cac gtg ggt cga gtg ttg gta tcg cgc acc caa ccg 259 Ala Leu Glu His His Val Gly Arg Val Leu Val Ser Arg Thr Gln Pro 40 45 50 gcc aaa gca acc gaa gcg ggt gaa gtc ctt gtg caa gca gcg cgg aaa 307 Ala Lys Ala Thr Glu Ala Gly Glu Val Leu Val Gln Ala Ala Arg Lys 55 60 65 atg gtg ttg ctg caa gca gaa act aaa gcg caa cta tct gga cgc ctt 355 Met Val Leu Leu Gln Ala Glu Thr Lys Ala Gln Leu Ser Gly Arg Leu 70 75 80 85 gct gaa atc ccg tta acc atc gcc atc aac gca gat tcg cta tcc aca 403 Ala Glu Ile Pro Leu Thr Ile Ala Ile Asn Ala Asp Ser Leu Ser Thr 90 95 100 tgg ttt cct ccc gtg ttc aac gag gta gct tct tgg ggt gga gca acg 451 Trp Phe Pro Pro Val Phe Asn Glu Val Ala Ser Trp Gly Gly Ala Thr 105 110 115 ctc acg ctg cgc ttg gaa gat gaa gcg cac aca tta tcc ttg ctg cgg 499 Leu Thr Leu Arg Leu Glu Asp Glu Ala His Thr Leu Ser Leu Leu Arg 120 125 130 cgt gga gat gtt tta gga gcg gta acc cgt gaa gct aat ccc gtg gcg 547 Arg Gly Asp Val Leu Gly Ala Val Thr Arg Glu Ala Asn Pro Val Ala 135 140 145 gga tgt gaa gta gta gaa ctt gga acc atg cgc cac ttg gcc att gca 595 Gly Cys Glu Val Val Glu Leu Gly Thr Met Arg His Leu Ala Ile Ala 150 155 160 165 acc ccc tca ttg cgg gat gcc tac atg gtt gat ggg aaa cta gat tgg 643 Thr Pro Ser Leu Arg Asp Ala Tyr Met Val Asp Gly Lys Leu Asp Trp 170 175 180 gct gcg atg ccc gtc tta cgc ttc ggt ccc aaa gat gtg ctt caa gac 691 Ala Ala Met Pro Val Leu Arg Phe Gly Pro Lys Asp Val Leu Gln Asp 185 190 195 cgt gac ctg gac ggg cgc gtc gat ggt cct gtg ggg cgc agg cgc gta 739 Arg Asp Leu Asp Gly Arg Val Asp Gly Pro Val Gly Arg Arg Arg Val 200 205 210 tcc att gtc ccg tcg gcg gaa ggt ttt ggt gag gca att cgc cga ggc 787 Ser Ile Val Pro Ser Ala Glu Gly Phe Gly Glu Ala Ile Arg Arg Gly 215 220 225 ctt ggt tgg gga ctt ctt ccc gaa acc caa gct gct ccc atg cta aaa 835 Leu Gly Trp Gly Leu Leu Pro Glu Thr Gln Ala Ala Pro Met Leu Lys 230 235 240 245 gca gga gaa gtg atc ctc ctc gat gag ata ccc att gac aca ccg atg 883 Ala Gly Glu Val Ile Leu Leu Asp Glu Ile Pro Ile Asp Thr Pro Met 250 255 260 tat tgg caa cga tgg cgc ctg gaa tct aga tct cta gct aga ctc aca 931 Tyr Trp Gln Arg Trp Arg Leu Glu Ser Arg Ser Leu Ala Arg Leu Thr 265 270 275 gac gcc gtc gtt gat gca gca atc gag gga ttg cgg cct tagttacttc 980 Asp Ala Val Val Asp Ala Ala Ile Glu Gly Leu Arg Pro 280 285 290 tgaaaaggtt cag 993 <210> 50 <211> 290 <212> PRT <213> Corynebacterium glutamicum <400> 50 Met Asn Pro Ile Gln Leu Asp Thr Leu Leu Ser Ile Ile Asp Glu Gly 1 5 10 15 Ser Phe Glu Gly Ala Ser Leu Ala Leu Ser Ile Ser Pro Ser Ala Val 20 25 30 Ser Gln Arg Val Lys Ala Leu Glu His His Val Gly Arg Val Leu Val 35 40 45 Ser Arg Thr Gln Pro Ala Lys Ala Thr Glu Ala Gly Glu Val Leu Val 50 55 60 Gln Ala Ala Arg Lys Met Val Leu Leu Gln Ala Glu Thr Lys Ala Gln 65 70 75 80 Leu Ser Gly Arg Leu Ala Glu Ile Pro Leu Thr Ile Ala Ile Asn Ala 85 90 95 Asp Ser Leu Ser Thr Trp Phe Pro Pro Val Phe Asn Glu Val Ala Ser 100 105 110 Trp Gly Gly Ala Thr Leu Thr Leu Arg Leu Glu Asp Glu Ala His Thr 115 120 125 Leu Ser Leu Leu Arg Arg Gly Asp Val Leu Gly Ala Val Thr Arg Glu 130 135 140 Ala Asn Pro Val Ala Gly Cys Glu Val Val Glu Leu Gly Thr Met Arg 145 150 155 160 His Leu Ala Ile Ala Thr Pro Ser Leu Arg Asp Ala Tyr Met Val Asp 165 170 175 Gly Lys Leu Asp Trp Ala Ala Met Pro Val Leu Arg Phe Gly Pro Lys 180 185 190 Asp Val Leu Gln Asp Arg Asp Leu Asp Gly Arg Val Asp Gly Pro Val 195 200 205 Gly Arg Arg Arg Val Ser Ile Val Pro Ser Ala Glu Gly Phe Gly Glu 210 215 220 Ala Ile Arg Arg Gly Leu Gly Trp Gly Leu Leu Pro Glu Thr Gln Ala 225 230 235 240 Ala Pro Met Leu Lys Ala Gly Glu Val Ile Leu Leu Asp Glu Ile Pro 245 250 255 Ile Asp Thr Pro Met Tyr Trp Gln Arg Trp Arg Leu Glu Ser Arg Ser 260 265 270 Leu Ala Arg Leu Thr Asp Ala Val Val Asp Ala Ala Ile Glu Gly Leu 275 280 285 Arg Pro 290 <210> 51 <211> 1626 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1603) <223> RXA00241 <400> 51 ggtctccagc ctttctaaac aattcatctg cacttgatta attggcccca agattacgcg 60 aagtttagcg acttcgccgt acgtcaacta cgttaaatga gtg aat act caa tca 115 Val Asn Thr Gln Ser 1 5 gat tct gcg ggg tct caa ggt gca gcg gcc aca agt cgt act gta tct 163 Asp Ser Ala Gly Ser Gln Gly Ala Ala Ala Thr Ser Arg Thr Val Ser 10 15 20 att aga acc ctc atc gcg ctg atc atc gga tcg acc gtc ggc gcg gga 211 Ile Arg Thr Leu Ile Ala Leu Ile Ile Gly Ser Thr Val Gly Ala Gly 25 30 35 att ttc tcc atc cct caa aac atc ggc tca gtc gca ggt ccc ggc gcg 259 Ile Phe Ser Ile Pro Gln Asn Ile Gly Ser Val Ala Gly Pro Gly Ala 40 45 50 atg ctc atc ggc tgg ctg atc gcc ggt gtg ggc atg ttg tcc gta gcg 307 Met Leu Ile Gly Trp Leu Ile Ala Gly Val Gly Met Leu Ser Val Ala 55 60 65 ttc gtg ttc cat gtt ctt gcc cgc cgt aaa cct cac ctc gat tct ggc 355 Phe Val Phe His Val Leu Ala Arg Arg Lys Pro His Leu Asp Ser Gly 70 75 80 85 gtc tac gca tat gcg cgt gtt gga ttg ggc gat tat gta ggt ttc tcc 403 Val Tyr Ala Tyr Ala Arg Val Gly Leu Gly Asp Tyr Val Gly Phe Ser 90 95 100 tcc gct tgg ggt tat tgg ctg ggt tca gtc atc gcc caa gtt ggc tac 451 Ser Ala Trp Gly Tyr Trp Leu Gly Ser Val Ile Ala Gln Val Gly Tyr 105 110 115 gca acg tta ttt ttc tcc acg ttg ggc cac tac gta ccg ctg ttt tcc 499 Ala Thr Leu Phe Phe Ser Thr Leu Gly His Tyr Val Pro Leu Phe Ser 120 125 130 caa gat cat cca ttt gtg tca gcg ttg gca gtt agc gct ttg acc tgg 547 Gln Asp His Pro Phe Val Ser Ala Leu Ala Val Ser Ala Leu Thr Trp 135 140 145 ctg gtg ttt gga gtt gtt tcc cga gga att agc caa gct gct ttc ttg 595 Leu Val Phe Gly Val Val Ser Arg Gly Ile Ser Gln Ala Ala Phe Leu 150 155 160 165 aca acg gtc acc acc gtg gcc aaa att ctg cct ctg ttg tgc ttc atc 643 Thr Thr Val Thr Thr Val Ala Lys Ile Leu Pro Leu Leu Cys Phe Ile 170 175 180 atc ctt gtt gca ttc ttg ggc ttt agc tgg gag aag ttc act gtt gat 691 Ile Leu Val Ala Phe Leu Gly Phe Ser Trp Glu Lys Phe Thr Val Asp 185 190 195 tta tgg gcg cgt gat ggt ggc gtg ggc agc att ttt gat cag gtg cgc 739 Leu Trp Ala Arg Asp Gly Gly Val Gly Ser Ile Phe Asp Gln Val Arg 200 205 210 ggc atc atg gtg tac acc gtg tgg gtg ttc atc ggt atc gaa ggt gca 787 Gly Ile Met Val Tyr Thr Val Trp Val Phe Ile Gly Ile Glu Gly Ala 215 220 225 tcg gta tat tcc cgc cag gca cgc tca cgc agt gat gtc agc cga gct 835 Ser Val Tyr Ser Arg Gln Ala Arg Ser Arg Ser Asp Val Ser Arg Ala 230 235 240 245 acc gtg att ggt ttt gtg gct gtt ctc ctt ttg ctg gtg tcg att tct 883 Thr Val Ile Gly Phe Val Ala Val Leu Leu Leu Leu Val Ser Ile Ser 250 255 260 tcg ctg agc ttc ggt gta ctg acc caa caa gag ctc gct gcg tta cca 931 Ser Leu Ser Phe Gly Val Leu Thr Gln Gln Glu Leu Ala Ala Leu Pro 265 270 275 gat aat tcc atg gcg tcg gtg ctc gaa gct gtt gtt ggt cca tgg ggt 979 Asp Asn Ser Met Ala Ser Val Leu Glu Ala Val Val Gly Pro Trp Gly 280 285 290 gcc gca ttg att tcg ttg ggt ctg tgt ctt tcg gtt ctt ggg gcc tat 1027 Ala Ala Leu Ile Ser Leu Gly Leu Cys Leu Ser Val Leu Gly Ala Tyr 295 300 305 gtg tcc tgg cag atg ctc tgc gca gaa cca ctg gcg ttg atg gca atg 1075 Val Ser Trp Gln Met Leu Cys Ala Glu Pro Leu Ala Leu Met Ala Met 310 315 320 325 gat ggc ctc att cca agc aaa atc ggg gcc atc aac agc cgc ggt gct 1123 Asp Gly Leu Ile Pro Ser Lys Ile Gly Ala Ile Asn Ser Arg Gly Ala 330 335 340 gcc tgg atg gct cag ctg atc tcc acc atc gtg att cag att ttc atc 1171 Ala Trp Met Ala Gln Leu Ile Ser Thr Ile Val Ile Gln Ile Phe Ile 345 350 355 atc att ttc ttc ctc aac gag acc acc tac gtc tcc atg gtg caa ttg 1219 Ile Ile Phe Phe Leu Asn Glu Thr Thr Tyr Val Ser Met Val Gln Leu 360 365 370 gct acc aac cta tac ttg gtg cct tac ctg ttc tct gcc ttt tat ctg 1267 Ala Thr Asn Leu Tyr Leu Val Pro Tyr Leu Phe Ser Ala Phe Tyr Leu 375 380 385 gtc atg ctg gca aca cgt gga aaa gga atc acc cac cca cat gcc ggc 1315 Val Met Leu Ala Thr Arg Gly Lys Gly Ile Thr His Pro His Ala Gly 390 395 400 405 aca cgt ttt gat gat tcc ggt cca gag ata tcc cgc cga gaa aac cgc 1363 Thr Arg Phe Asp Asp Ser Gly Pro Glu Ile Ser Arg Arg Glu Asn Arg 410 415 420 aaa cac ctc atc gtc ggt tta gta gca acg gtg tat tca gtg tgg ctg 1411 Lys His Leu Ile Val Gly Leu Val Ala Thr Val Tyr Ser Val Trp Leu 425 430 435 ttt tac gct gca gaa ccg cag ttt gtc ctc ttc gga gcc atg gcg atg 1459 Phe Tyr Ala Ala Glu Pro Gln Phe Val Leu Phe Gly Ala Met Ala Met 440 445 450 ctt ccc ggc tta atc ccc tat gtg tgg aca agg att tat cgt ggc gaa 1507 Leu Pro Gly Leu Ile Pro Tyr Val Trp Thr Arg Ile Tyr Arg Gly Glu 455 460 465 cag gtg ttt aac cgc ttt gaa atc ggc gtg gtt gtt gtc ctg gtc gtt 1555 Gln Val Phe Asn Arg Phe Glu Ile Gly Val Val Val Val Leu Val Val 470 475 480 485 gct gcc agc gcg ggc gtt att ggt ttg gtc aac gga tca cta tcg ctt 1603 Ala Ala Ser Ala Gly Val Ile Gly Leu Val Asn Gly Ser Leu Ser Leu 490 495 500 taaacaccga aaccttcctg cta 1626 <210> 52 <211> 501 <212> PRT <213> Corynebacterium glutamicum <400> 52 Val Asn Thr Gln Ser Asp Ser Ala Gly Ser Gln Gly Ala Ala Ala Thr 1 5 10 15 Ser Arg Thr Val Ser Ile Arg Thr Leu Ile Ala Leu Ile Ile Gly Ser 20 25 30 Thr Val Gly Ala Gly Ile Phe Ser Ile Pro Gln Asn Ile Gly Ser Val 35 40 45 Ala Gly Pro Gly Ala Met Leu Ile Gly Trp Leu Ile Ala Gly Val Gly 50 55 60 Met Leu Ser Val Ala Phe Val Phe His Val Leu Ala Arg Arg Lys Pro 65 70 75 80 His Leu Asp Ser Gly Val Tyr Ala Tyr Ala Arg Val Gly Leu Gly Asp 85 90 95 Tyr Val Gly Phe Ser Ser Ala Trp Gly Tyr Trp Leu Gly Ser Val Ile 100 105 110 Ala Gln Val Gly Tyr Ala Thr Leu Phe Phe Ser Thr Leu Gly His Tyr 115 120 125 Val Pro Leu Phe Ser Gln Asp His Pro Phe Val Ser Ala Leu Ala Val 130 135 140 Ser Ala Leu Thr Trp Leu Val Phe Gly Val Val Ser Arg Gly Ile Ser 145 150 155 160 Gln Ala Ala Phe Leu Thr Thr Val Thr Thr Val Ala Lys Ile Leu Pro 165 170 175 Leu Leu Cys Phe Ile Ile Leu Val Ala Phe Leu Gly Phe Ser Trp Glu 180 185 190 Lys Phe Thr Val Asp Leu Trp Ala Arg Asp Gly Gly Val Gly Ser Ile 195 200 205 Phe Asp Gln Val Arg Gly Ile Met Val Tyr Thr Val Trp Val Phe Ile 210 215 220 Gly Ile Glu Gly Ala Ser Val Tyr Ser Arg Gln Ala Arg Ser Arg Ser 225 230 235 240 Asp Val Ser Arg Ala Thr Val Ile Gly Phe Val Ala Val Leu Leu Leu 245 250 255 Leu Val Ser Ile Ser Ser Leu Ser Phe Gly Val Leu Thr Gln Gln Glu 260 265 270 Leu Ala Ala Leu Pro Asp Asn Ser Met Ala Ser Val Leu Glu Ala Val 275 280 285 Val Gly Pro Trp Gly Ala Ala Leu Ile Ser Leu Gly Leu Cys Leu Ser 290 295 300 Val Leu Gly Ala Tyr Val Ser Trp Gln Met Leu Cys Ala Glu Pro Leu 305 310 315 320 Ala Leu Met Ala Met Asp Gly Leu Ile Pro Ser Lys Ile Gly Ala Ile 325 330 335 Asn Ser Arg Gly Ala Ala Trp Met Ala Gln Leu Ile Ser Thr Ile Val 340 345 350 Ile Gln Ile Phe Ile Ile Ile Phe Phe Leu Asn Glu Thr Thr Tyr Val 355 360 365 Ser Met Val Gln Leu Ala Thr Asn Leu Tyr Leu Val Pro Tyr Leu Phe 370 375 380 Ser Ala Phe Tyr Leu Val Met Leu Ala Thr Arg Gly Lys Gly Ile Thr 385 390 395 400 His Pro His Ala Gly Thr Arg Phe Asp Asp Ser Gly Pro Glu Ile Ser 405 410 415 Arg Arg Glu Asn Arg Lys His Leu Ile Val Gly Leu Val Ala Thr Val 420 425 430 Tyr Ser Val Trp Leu Phe Tyr Ala Ala Glu Pro Gln Phe Val Leu Phe 435 440 445 Gly Ala Met Ala Met Leu Pro Gly Leu Ile Pro Tyr Val Trp Thr Arg 450 455 460 Ile Tyr Arg Gly Glu Gln Val Phe Asn Arg Phe Glu Ile Gly Val Val 465 470 475 480 Val Val Leu Val Val Ala Ala Ser Ala Gly Val Ile Gly Leu Val Asn 485 490 495 Gly Ser Leu Ser Leu 500 <210> 53 <211> 822 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(799) <223> RXA01394 <400> 53 gagcaaagtg tccagttgaa tggggttcat gaagctatat taaaccatgt taagaaccaa 60 tcattttact taagtacttc cataggtcac gatggtgatc atg gaa atc ttc att 115 Met Glu Ile Phe Ile 1 5 aca ggt ctg ctt ttg ggg gcc agt ctt tta ctg tcc atc gga ccg cag 163 Thr Gly Leu Leu Leu Gly Ala Ser Leu Leu Leu Ser Ile Gly Pro Gln 10 15 20 aat gta ctg gtg att aaa caa gga att aag cgc gaa gga ctc att gcg 211 Asn Val Leu Val Ile Lys Gln Gly Ile Lys Arg Glu Gly Leu Ile Ala 25 30 35 gtt ctt ctc gtg tgt tta att tct gac gtc ttt ttg ttc atc gcc ggc 259 Val Leu Leu Val Cys Leu Ile Ser Asp Val Phe Leu Phe Ile Ala Gly 40 45 50 acc ttg ggc gtt gat ctt ttg tcc aat gcc gcg ccg atc gtg ctc gat 307 Thr Leu Gly Val Asp Leu Leu Ser Asn Ala Ala Pro Ile Val Leu Asp 55 60 65 att atg cgc tgg ggt ggc atc gct tac ctg tta tgg ttt gcc gtc atg 355 Ile Met Arg Trp Gly Gly Ile Ala Tyr Leu Leu Trp Phe Ala Val Met 70 75 80 85 gca gcg aaa gac gcc atg aca aac aag gtg gaa gcg cca cag atc att 403 Ala Ala Lys Asp Ala Met Thr Asn Lys Val Glu Ala Pro Gln Ile Ile 90 95 100 gaa gaa aca gaa cca acc gtg ccc gat gac acg cct ttg ggc ggt tcg 451 Glu Glu Thr Glu Pro Thr Val Pro Asp Asp Thr Pro Leu Gly Gly Ser 105 110 115 gcg gtg gcc act gac acg cgc aac cgg gtg cgg gtg gag gtg agc gtc 499 Ala Val Ala Thr Asp Thr Arg Asn Arg Val Arg Val Glu Val Ser Val 120 125 130 gat aag cag cgg gtt tgg gta aag ccc atg ttg atg gca atc gtg ctg 547 Asp Lys Gln Arg Val Trp Val Lys Pro Met Leu Met Ala Ile Val Leu 135 140 145 acc tgg ttg aac ccg aat gcg tat ttg gac gcg ttt gtg ttt atc ggc 595 Thr Trp Leu Asn Pro Asn Ala Tyr Leu Asp Ala Phe Val Phe Ile Gly 150 155 160 165 ggc gtc ggc gcg caa tac ggc gac acc gga cgg tgg att ttc gcc gct 643 Gly Val Gly Ala Gln Tyr Gly Asp Thr Gly Arg Trp Ile Phe Ala Ala 170 175 180 ggc gcg ttc gcg gca agc ctg atc tgg ttc ccg ctg gtg ggt ttc ggc 691 Gly Ala Phe Ala Ala Ser Leu Ile Trp Phe Pro Leu Val Gly Phe Gly 185 190 195 gca gca gca ttg tca cgc ccg ctg tcc agc ccc aag gtg tgg cgc tgg 739 Ala Ala Ala Leu Ser Arg Pro Leu Ser Ser Pro Lys Val Trp Arg Trp 200 205 210 atc aac gtc gtc gtg gca gtt gtg atg acc gca ttg gcc atc aaa ctg 787 Ile Asn Val Val Val Ala Val Val Met Thr Ala Leu Ala Ile Lys Leu 215 220 225 atg ttg atg ggt tagttttcgc gggttttgga atc 822 Met Leu Met Gly 230 <210> 54 <211> 233 <212> PRT <213> Corynebacterium glutamicum <400> 54 Met Glu Ile Phe Ile Thr Gly Leu Leu Leu Gly Ala Ser Leu Leu Leu 1 5 10 15 Ser Ile Gly Pro Gln Asn Val Leu Val Ile Lys Gln Gly Ile Lys Arg 20 25 30 Glu Gly Leu Ile Ala Val Leu Leu Val Cys Leu Ile Ser Asp Val Phe 35 40 45 Leu Phe Ile Ala Gly Thr Leu Gly Val Asp Leu Leu Ser Asn Ala Ala 50 55 60 Pro Ile Val Leu Asp Ile Met Arg Trp Gly Gly Ile Ala Tyr Leu Leu 65 70 75 80 Trp Phe Ala Val Met Ala Ala Lys Asp Ala Met Thr Asn Lys Val Glu 85 90 95 Ala Pro Gln Ile Ile Glu Glu Thr Glu Pro Thr Val Pro Asp Asp Thr 100 105 110 Pro Leu Gly Gly Ser Ala Val Ala Thr Asp Thr Arg Asn Arg Val Arg 115 120 125 Val Glu Val Ser Val Asp Lys Gln Arg Val Trp Val Lys Pro Met Leu 130 135 140 Met Ala Ile Val Leu Thr Trp Leu Asn Pro Asn Ala Tyr Leu Asp Ala 145 150 155 160 Phe Val Phe Ile Gly Gly Val Gly Ala Gln Tyr Gly Asp Thr Gly Arg 165 170 175 Trp Ile Phe Ala Ala Gly Ala Phe Ala Ala Ser Leu Ile Trp Phe Pro 180 185 190 Leu Val Gly Phe Gly Ala Ala Ala Leu Ser Arg Pro Leu Ser Ser Pro 195 200 205 Lys Val Trp Arg Trp Ile Asn Val Val Val Ala Val Val Met Thr Ala 210 215 220 Leu Ala Ile Lys Leu Met Leu Met Gly 225 230 <210> 55 <211> 1026 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1003) <223> RXA00865 <400> 55 ttatcggaat gtggcttggg cgattgttat gcaaaagttg ttaggttttt tgcggggttg 60 tttaaccccc aaatgaggga agaaggtaac cttgaactct atg agc aca ggt tta 115 Met Ser Thr Gly Leu 1 5 aca gct aag acc gga gta gag cac ttc ggc acc gtt gga gta gca atg 163 Thr Ala Lys Thr Gly Val Glu His Phe Gly Thr Val Gly Val Ala Met 10 15 20 gtt act cca ttc acg gaa tcc gga gac atc gat atc gct gct ggc cgc 211 Val Thr Pro Phe Thr Glu Ser Gly Asp Ile Asp Ile Ala Ala Gly Arg 25 30 35 gaa gtc gcg gct tat ttg gtt gat aag ggc ttg gat tct ttg gtt ctc 259 Glu Val Ala Ala Tyr Leu Val Asp Lys Gly Leu Asp Ser Leu Val Leu 40 45 50 gcg ggc acc act ggt gaa tcc cca acg aca acc gcc gct gaa aaa cta 307 Ala Gly Thr Thr Gly Glu Ser Pro Thr Thr Thr Ala Ala Glu Lys Leu 55 60 65 gaa ctg ctc aag gcc gtt cgt gag gaa gtt ggg gat cgg gcg aag ctc 355 Glu Leu Leu Lys Ala Val Arg Glu Glu Val Gly Asp Arg Ala Lys Leu 70 75 80 85 atc gcc ggt gtc gga acc aac aac acg cgg aca tct gtg gaa ctt gcg 403 Ile Ala Gly Val Gly Thr Asn Asn Thr Arg Thr Ser Val Glu Leu Ala 90 95 100 gaa gct gct gct tct gct ggc gca gac ggc ctt tta gtt gta act cct 451 Glu Ala Ala Ala Ser Ala Gly Ala Asp Gly Leu Leu Val Val Thr Pro 105 110 115 tat tac tcc aag ccg agc caa gag gga ttg ctg gcg cac ttc ggt gca 499 Tyr Tyr Ser Lys Pro Ser Gln Glu Gly Leu Leu Ala His Phe Gly Ala 120 125 130 att gct gca gca aca gag gtt cca att tgt ctc tat gac att cct ggt 547 Ile Ala Ala Ala Thr Glu Val Pro Ile Cys Leu Tyr Asp Ile Pro Gly 135 140 145 cgg tca ggt att cca att gag tct gat acc atg aga cgc ctg agt gaa 595 Arg Ser Gly Ile Pro Ile Glu Ser Asp Thr Met Arg Arg Leu Ser Glu 150 155 160 165 tta cct acg att ttg gcg gtc aag gac gcc aag ggt gac ctc gtt gca 643 Leu Pro Thr Ile Leu Ala Val Lys Asp Ala Lys Gly Asp Leu Val Ala 170 175 180 gcc acg tca ttg atc aaa gaa acg gga ctt gcc tgg tat tca ggc gat 691 Ala Thr Ser Leu Ile Lys Glu Thr Gly Leu Ala Trp Tyr Ser Gly Asp 185 190 195 gac cca cta aac ctt gtt tgg ctt gct ttg ggc gga tca ggt ttc att 739 Asp Pro Leu Asn Leu Val Trp Leu Ala Leu Gly Gly Ser Gly Phe Ile 200 205 210 tcc gta att gga cat gca gcc ccc aca gca tta cgt gag ttg tac aca 787 Ser Val Ile Gly His Ala Ala Pro Thr Ala Leu Arg Glu Leu Tyr Thr 215 220 225 agc ttc gag gaa ggc gac ctc gtc cgt gcg cgg gaa atc aac gcc aaa 835 Ser Phe Glu Glu Gly Asp Leu Val Arg Ala Arg Glu Ile Asn Ala Lys 230 235 240 245 cta tca ccg ctg gta gct gcc caa ggt cgc ttg ggt gga gtc agc ttg 883 Leu Ser Pro Leu Val Ala Ala Gln Gly Arg Leu Gly Gly Val Ser Leu 250 255 260 gca aaa gct gct ctg cgt ctg cag ggc atc aac gta gga gat cct cga 931 Ala Lys Ala Ala Leu Arg Leu Gln Gly Ile Asn Val Gly Asp Pro Arg 265 270 275 ctt cca att atg gct cca aat gag cag gaa ctt gag gct ctc cga gaa 979 Leu Pro Ile Met Ala Pro Asn Glu Gln Glu Leu Glu Ala Leu Arg Glu 280 285 290 gac atg aaa aaa gct gga gtt cta taaatatgaa tgattcccga aat 1026 Asp Met Lys Lys Ala Gly Val Leu 295 300 <210> 56 <211> 301 <212> PRT <213> Corynebacterium glutamicum <400> 56 Met Ser Thr Gly Leu Thr Ala Lys Thr Gly Val Glu His Phe Gly Thr 1 5 10 15 Val Gly Val Ala Met Val Thr Pro Phe Thr Glu Ser Gly Asp Ile Asp 20 25 30 Ile Ala Ala Gly Arg Glu Val Ala Ala Tyr Leu Val Asp Lys Gly Leu 35 40 45 Asp Ser Leu Val Leu Ala Gly Thr Thr Gly Glu Ser Pro Thr Thr Thr 50 55 60 Ala Ala Glu Lys Leu Glu Leu Leu Lys Ala Val Arg Glu Glu Val Gly 65 70 75 80 Asp Arg Ala Lys Leu Ile Ala Gly Val Gly Thr Asn Asn Thr Arg Thr 85 90 95 Ser Val Glu Leu Ala Glu Ala Ala Ala Ser Ala Gly Ala Asp Gly Leu 100 105 110 Leu Val Val Thr Pro Tyr Tyr Ser Lys Pro Ser Gln Glu Gly Leu Leu 115 120 125 Ala His Phe Gly Ala Ile Ala Ala Ala Thr Glu Val Pro Ile Cys Leu 130 135 140 Tyr Asp Ile Pro Gly Arg Ser Gly Ile Pro Ile Glu Ser Asp Thr Met 145 150 155 160 Arg Arg Leu Ser Glu Leu Pro Thr Ile Leu Ala Val Lys Asp Ala Lys 165 170 175 Gly Asp Leu Val Ala Ala Thr Ser Leu Ile Lys Glu Thr Gly Leu Ala 180 185 190 Trp Tyr Ser Gly Asp Asp Pro Leu Asn Leu Val Trp Leu Ala Leu Gly 195 200 205 Gly Ser Gly Phe Ile Ser Val Ile Gly His Ala Ala Pro Thr Ala Leu 210 215 220 Arg Glu Leu Tyr Thr Ser Phe Glu Glu Gly Asp Leu Val Arg Ala Arg 225 230 235 240 Glu Ile Asn Ala Lys Leu Ser Pro Leu Val Ala Ala Gln Gly Arg Leu 245 250 255 Gly Gly Val Ser Leu Ala Lys Ala Ala Leu Arg Leu Gln Gly Ile Asn 260 265 270 Val Gly Asp Pro Arg Leu Pro Ile Met Ala Pro Asn Glu Gln Glu Leu 275 280 285 Glu Ala Leu Arg Glu Asp Met Lys Lys Ala Gly Val Leu 290 295 300 <210> 57 <211> 1071 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1048) <223> RXS02021 <400> 57 ttgggtcgcc gaggagatct aatcctggtt tgagttcaga gttcacaggt ttaagcctac 60 aaaccttagt taaaacatga tggaagcggt cgattaaaaa atg agt gaa aac att 115 Met Ser Glu Asn Ile 1 5 cgc gga gcc caa gca gtt gga atc gca aat atc gcc atg gac ggg acc 163 Arg Gly Ala Gln Ala Val Gly Ile Ala Asn Ile Ala Met Asp Gly Thr 10 15 20 atc ctg gac acg tgg tac cca gaa ccc caa att ttc aac ccg gat cag 211 Ile Leu Asp Thr Trp Tyr Pro Glu Pro Gln Ile Phe Asn Pro Asp Gln 25 30 35 tgg gct gaa cgc tac cca ttg gaa gtg ggc acc aca cgc ctc gga gca 259 Trp Ala Glu Arg Tyr Pro Leu Glu Val Gly Thr Thr Arg Leu Gly Ala 40 45 50 aac gaa ctc acc cca cgg atg ctg cag ttg gta aaa ctg gac caa gat 307 Asn Glu Leu Thr Pro Arg Met Leu Gln Leu Val Lys Leu Asp Gln Asp 55 60 65 cgc ctc gtc gaa cag gta gca gtc cgc acc gtt atc ccc gat ctg tct 355 Arg Leu Val Glu Gln Val Ala Val Arg Thr Val Ile Pro Asp Leu Ser 70 75 80 85 caa cct cca gta gac gcg cac gat gtt tac ctg cgc ctc cac ctg ctt 403 Gln Pro Pro Val Asp Ala His Asp Val Tyr Leu Arg Leu His Leu Leu 90 95 100 tcc cac cgg ctg gtc cgc ccc cac gaa atg cac atg caa aac acc ttg 451 Ser His Arg Leu Val Arg Pro His Glu Met His Met Gln Asn Thr Leu 105 110 115 gag ctg ctg tcc gac gtg gtg tgg aca aac aag ggc cct tgc ctt cct 499 Glu Leu Leu Ser Asp Val Val Trp Thr Asn Lys Gly Pro Cys Leu Pro 120 125 130 gaa aac ttt gag tgg gtg cgt ggt gct ctg cgg tcc cgc gga ctc atc 547 Glu Asn Phe Glu Trp Val Arg Gly Ala Leu Arg Ser Arg Gly Leu Ile 135 140 145 cac gtc tac tgt gtg gac cgt ctt ccc cgc atg gtc gac tat gtg gtt 595 His Val Tyr Cys Val Asp Arg Leu Pro Arg Met Val Asp Tyr Val Val 150 155 160 165 ccc cct gga gtc cgc atc tcc gaa gca gaa cgc gtg cgc cta ggt gca 643 Pro Pro Gly Val Arg Ile Ser Glu Ala Glu Arg Val Arg Leu Gly Ala 170 175 180 tac ctt gct ccg ggt acc tct gtg ctg cgt gaa ggt ttc gtg tct ttc 691 Tyr Leu Ala Pro Gly Thr Ser Val Leu Arg Glu Gly Phe Val Ser Phe 185 190 195 aac tcc ggc acc ttg ggt gcc gca aag gtg gaa ggc cgc ctg agt tcc 739 Asn Ser Gly Thr Leu Gly Ala Ala Lys Val Glu Gly Arg Leu Ser Ser 200 205 210 ggt gtg gtc atc ggt gaa ggt tcc gag att gga ctg tct tct act att 787 Gly Val Val Ile Gly Glu Gly Ser Glu Ile Gly Leu Ser Ser Thr Ile 215 220 225 cag tcc ccg aga gat gaa cag cgc cgc cgt ttg ccg ttg agc atc ggc 835 Gln Ser Pro Arg Asp Glu Gln Arg Arg Arg Leu Pro Leu Ser Ile Gly 230 235 240 245 caa aac tgc aac ttt ggt gtc agc tcc gga atc atc gga gtc agt ctg 883 Gln Asn Cys Asn Phe Gly Val Ser Ser Gly Ile Ile Gly Val Ser Leu 250 255 260 gga gac aat tgc gac atc gga aat aac att gtc ttg gat gga gat acc 931 Gly Asp Asn Cys Asp Ile Gly Asn Asn Ile Val Leu Asp Gly Asp Thr 265 270 275 ccc att tgg ttc gca gcc gat gag gag tta cgc act atc gac tcc atc 979 Pro Ile Trp Phe Ala Ala Asp Glu Glu Leu Arg Thr Ile Asp Ser Ile 280 285 290 gaa ggc caa gca aat tgg tca atc aag cgt gaa tcc ggc ttc cat gag 1027 Glu Gly Gln Ala Asn Trp Ser Ile Lys Arg Glu Ser Gly Phe His Glu 295 300 305 cca gtt gcc cgc ctc aaa gct tgacccattt tcataaccag tgc 1071 Pro Val Ala Arg Leu Lys Ala 310 315 <210> 58 <211> 316 <212> PRT <213> Corynebacterium glutamicum <400> 58 Met Ser Glu Asn Ile Arg Gly Ala Gln Ala Val Gly Ile Ala Asn Ile 1 5 10 15 Ala Met Asp Gly Thr Ile Leu Asp Thr Trp Tyr Pro Glu Pro Gln Ile 20 25 30 Phe Asn Pro Asp Gln Trp Ala Glu Arg Tyr Pro Leu Glu Val Gly Thr 35 40 45 Thr Arg Leu Gly Ala Asn Glu Leu Thr Pro Arg Met Leu Gln Leu Val 50 55 60 Lys Leu Asp Gln Asp Arg Leu Val Glu Gln Val Ala Val Arg Thr Val 65 70 75 80 Ile Pro Asp Leu Ser Gln Pro Pro Val Asp Ala His Asp Val Tyr Leu 85 90 95 Arg Leu His Leu Leu Ser His Arg Leu Val Arg Pro His Glu Met His 100 105 110 Met Gln Asn Thr Leu Glu Leu Leu Ser Asp Val Val Trp Thr Asn Lys 115 120 125 Gly Pro Cys Leu Pro Glu Asn Phe Glu Trp Val Arg Gly Ala Leu Arg 130 135 140 Ser Arg Gly Leu Ile His Val Tyr Cys Val Asp Arg Leu Pro Arg Met 145 150 155 160 Val Asp Tyr Val Val Pro Pro Gly Val Arg Ile Ser Glu Ala Glu Arg 165 170 175 Val Arg Leu Gly Ala Tyr Leu Ala Pro Gly Thr Ser Val Leu Arg Glu 180 185 190 Gly Phe Val Ser Phe Asn Ser Gly Thr Leu Gly Ala Ala Lys Val Glu 195 200 205 Gly Arg Leu Ser Ser Gly Val Val Ile Gly Glu Gly Ser Glu Ile Gly 210 215 220 Leu Ser Ser Thr Ile Gln Ser Pro Arg Asp Glu Gln Arg Arg Arg Leu 225 230 235 240 Pro Leu Ser Ile Gly Gln Asn Cys Asn Phe Gly Val Ser Ser Gly Ile 245 250 255 Ile Gly Val Ser Leu Gly Asp Asn Cys Asp Ile Gly Asn Asn Ile Val 260 265 270 Leu Asp Gly Asp Thr Pro Ile Trp Phe Ala Ala Asp Glu Glu Leu Arg 275 280 285 Thr Ile Asp Ser Ile Glu Gly Gln Ala Asn Trp Ser Ile Lys Arg Glu 290 295 300 Ser Gly Phe His Glu Pro Val Ala Arg Leu Lys Ala 305 310 315 <210> 59 <211> 1296 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1273) <223> RXS02157 <400> 59 gggtggaatt ggcacgatgg tgctgccgga tgtttttgat cgggagaatt atcctgaagg 60 caccgttttt agaaaagacg acaaggatgg ggaactgtaa atg agc acg ctg gaa 115 Met Ser Thr Leu Glu 1 5 act tgg cca cag gtc att att aat acg tac ggc acc cca cca gtt gag 163 Thr Trp Pro Gln Val Ile Ile Asn Thr Tyr Gly Thr Pro Pro Val Glu 10 15 20 ctg gtg tcc ggc aag ggc gca acc gtc act gat gac cag ggc aat gtc 211 Leu Val Ser Gly Lys Gly Ala Thr Val Thr Asp Asp Gln Gly Asn Val 25 30 35 tac atc gac ttg ctc gcg ggc atc gca gtc aac gcg ttg ggc cac gcc 259 Tyr Ile Asp Leu Leu Ala Gly Ile Ala Val Asn Ala Leu Gly His Ala 40 45 50 cac ccg gcg atc atc gag gcg gtc acc aac cag atc ggc caa ctt ggt 307 His Pro Ala Ile Ile Glu Ala Val Thr Asn Gln Ile Gly Gln Leu Gly 55 60 65 cac gtc tca aac ttg ttc gca tcc agg ccc gtc gtc gag gtc gcc gag 355 His Val Ser Asn Leu Phe Ala Ser Arg Pro Val Val Glu Val Ala Glu 70 75 80 85 gag ctc atc aag cgt ttt tcg ctt gac gac gcc acc ctc gcc gcg caa 403 Glu Leu Ile Lys Arg Phe Ser Leu Asp Asp Ala Thr Leu Ala Ala Gln 90 95 100 acc cgg gtt ttc ttc tgc aac tcg ggc gcc gaa gca aac gag gct gct 451 Thr Arg Val Phe Phe Cys Asn Ser Gly Ala Glu Ala Asn Glu Ala Ala 105 110 115 ttc aag att gca cgc ttg act ggt cgt tcc cgg att ctg gct gca gtt 499 Phe Lys Ile Ala Arg Leu Thr Gly Arg Ser Arg Ile Leu Ala Ala Val 120 125 130 cat ggt ttc cac ggc cgc acc atg ggt tcc ctc gcg ctg act ggc cag 547 His Gly Phe His Gly Arg Thr Met Gly Ser Leu Ala Leu Thr Gly Gln 135 140 145 cca gac aag cgt gaa gcg ttc ctg cca atg cca agc ggt gtg gag ttc 595 Pro Asp Lys Arg Glu Ala Phe Leu Pro Met Pro Ser Gly Val Glu Phe 150 155 160 165 tac cct tac ggc gac acc gat tac ttg cgc aaa atg gta gaa acc aac 643 Tyr Pro Tyr Gly Asp Thr Asp Tyr Leu Arg Lys Met Val Glu Thr Asn 170 175 180 cca acg gat gtg gct gct atc ttc ctc gag cca atc cag ggt gaa acg 691 Pro Thr Asp Val Ala Ala Ile Phe Leu Glu Pro Ile Gln Gly Glu Thr 185 190 195 ggc gtt gtt cca gca cct gaa gga ttc ctc aag gca gtg cgc gag ctg 739 Gly Val Val Pro Ala Pro Glu Gly Phe Leu Lys Ala Val Arg Glu Leu 200 205 210 tgc gat gag tac ggc atc ttg atg atc acc gat gaa gtc cag act ggc 787 Cys Asp Glu Tyr Gly Ile Leu Met Ile Thr Asp Glu Val Gln Thr Gly 215 220 225 gtt ggc cgt acc ggc gat ttc ttt gca cat cag cac gat ggc gtt gtt 835 Val Gly Arg Thr Gly Asp Phe Phe Ala His Gln His Asp Gly Val Val 230 235 240 245 ccc gat gtg gtg acc atg gcc aag gga ctt ggc ggc ggt ctt ccc atc 883 Pro Asp Val Val Thr Met Ala Lys Gly Leu Gly Gly Gly Leu Pro Ile 250 255 260 ggt gct tgt ttg gcc act ggc cgt gca gct gaa ttg atg acc cca ggc 931 Gly Ala Cys Leu Ala Thr Gly Arg Ala Ala Glu Leu Met Thr Pro Gly 265 270 275 aag cac ggc acc act ttc ggt ggc aac cca gtt gct tgt gca gct gcc 979 Lys His Gly Thr Thr Phe Gly Gly Asn Pro Val Ala Cys Ala Ala Ala 280 285 290 aag gca gtg ctg tct gtt gtc gat gac gct ttc tgc gca gaa gtt gcc 1027 Lys Ala Val Leu Ser Val Val Asp Asp Ala Phe Cys Ala Glu Val Ala 295 300 305 cgc aag ggc gag ctg ttc aag gaa ctt ctt gcc aag gtt gac ggc gtt 1075 Arg Lys Gly Glu Leu Phe Lys Glu Leu Leu Ala Lys Val Asp Gly Val 310 315 320 325 gta gac gtc cgt ggc agg ggc ttg atg ttg ggc gtg gtg ctg gag cgc 1123 Val Asp Val Arg Gly Arg Gly Leu Met Leu Gly Val Val Leu Glu Arg 330 335 340 gac gtc gca aag caa gct gtt ctt gat ggt ttt aag cac ggc gtt att 1171 Asp Val Ala Lys Gln Ala Val Leu Asp Gly Phe Lys His Gly Val Ile 345 350 355 ttg aat gca ccg gcg gac aac att atc cgt ttg acc ccg ccg ctg gtg 1219 Leu Asn Ala Pro Ala Asp Asn Ile Ile Arg Leu Thr Pro Pro Leu Val 360 365 370 atc acc gac gaa gaa atc gca gac gca gtc aag gct att gcc gag aca 1267 Ile Thr Asp Glu Glu Ile Ala Asp Ala Val Lys Ala Ile Ala Glu Thr 375 380 385 atc gca taaaggactc aaacttatga ctt 1296 Ile Ala 390 <210> 60 <211> 391 <212> PRT <213> Corynebacterium glutamicum <400> 60 Met Ser Thr Leu Glu Thr Trp Pro Gln Val Ile Ile Asn Thr Tyr Gly 1 5 10 15 Thr Pro Pro Val Glu Leu Val Ser Gly Lys Gly Ala Thr Val Thr Asp 20 25 30 Asp Gln Gly Asn Val Tyr Ile Asp Leu Leu Ala Gly Ile Ala Val Asn 35 40 45 Ala Leu Gly His Ala His Pro Ala Ile Ile Glu Ala Val Thr Asn Gln 50 55 60 Ile Gly Gln Leu Gly His Val Ser Asn Leu Phe Ala Ser Arg Pro Val 65 70 75 80 Val Glu Val Ala Glu Glu Leu Ile Lys Arg Phe Ser Leu Asp Asp Ala 85 90 95 Thr Leu Ala Ala Gln Thr Arg Val Phe Phe Cys Asn Ser Gly Ala Glu 100 105 110 Ala Asn Glu Ala Ala Phe Lys Ile Ala Arg Leu Thr Gly Arg Ser Arg 115 120 125 Ile Leu Ala Ala Val His Gly Phe His Gly Arg Thr Met Gly Ser Leu 130 135 140 Ala Leu Thr Gly Gln Pro Asp Lys Arg Glu Ala Phe Leu Pro Met Pro 145 150 155 160 Ser Gly Val Glu Phe Tyr Pro Tyr Gly Asp Thr Asp Tyr Leu Arg Lys 165 170 175 Met Val Glu Thr Asn Pro Thr Asp Val Ala Ala Ile Phe Leu Glu Pro 180 185 190 Ile Gln Gly Glu Thr Gly Val Val Pro Ala Pro Glu Gly Phe Leu Lys 195 200 205 Ala Val Arg Glu Leu Cys Asp Glu Tyr Gly Ile Leu Met Ile Thr Asp 210 215 220 Glu Val Gln Thr Gly Val Gly Arg Thr Gly Asp Phe Phe Ala His Gln 225 230 235 240 His Asp Gly Val Val Pro Asp Val Val Thr Met Ala Lys Gly Leu Gly 245 250 255 Gly Gly Leu Pro Ile Gly Ala Cys Leu Ala Thr Gly Arg Ala Ala Glu 260 265 270 Leu Met Thr Pro Gly Lys His Gly Thr Thr Phe Gly Gly Asn Pro Val 275 280 285 Ala Cys Ala Ala Ala Lys Ala Val Leu Ser Val Val Asp Asp Ala Phe 290 295 300 Cys Ala Glu Val Ala Arg Lys Gly Glu Leu Phe Lys Glu Leu Leu Ala 305 310 315 320 Lys Val Asp Gly Val Val Asp Val Arg Gly Arg Gly Leu Met Leu Gly 325 330 335 Val Val Leu Glu Arg Asp Val Ala Lys Gln Ala Val Leu Asp Gly Phe 340 345 350 Lys His Gly Val Ile Leu Asn Ala Pro Ala Asp Asn Ile Ile Arg Leu 355 360 365 Thr Pro Pro Leu Val Ile Thr Asp Glu Glu Ile Ala Asp Ala Val Lys 370 375 380 Ala Ile Ala Glu Thr Ile Ala 385 390 <210> 61 <211> 1008 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(985) <223> RXC00733 <400> 61 acggcgaggt tgtcggtatt ggaacgcaca cgaatttgct gaacacgtgc ggtacctacc 60 gtgaaattgt tgaatcccaa gagactgcgc aggcgcaatc atg agt aat act gca 115 Met Ser Asn Thr Ala 1 5 ggc ccc cgc ggg cgt tcc cat cag gca gac gcc gcg ccg aat caa aag 163 Gly Pro Arg Gly Arg Ser His Gln Ala Asp Ala Ala Pro Asn Gln Lys 10 15 20 gca cag aat ttc gga cca tct gcc aaa agg ctt ttc gga att cta ggc 211 Ala Gln Asn Phe Gly Pro Ser Ala Lys Arg Leu Phe Gly Ile Leu Gly 25 30 35 cat gac cgt aac acc tta att ttt gtt atc ttc cta gcc gtc ctg agc 259 His Asp Arg Asn Thr Leu Ile Phe Val Ile Phe Leu Ala Val Leu Ser 40 45 50 gtt gga ctt acc gtc ttg ggc cca tgg ttg ctg ggt aaa gcc acc aac 307 Val Gly Leu Thr Val Leu Gly Pro Trp Leu Leu Gly Lys Ala Thr Asn 55 60 65 gtg gtg ttt gaa gga ttc cta tct aag cgc atg ccg gct ggt gcg tca 355 Val Val Phe Glu Gly Phe Leu Ser Lys Arg Met Pro Ala Gly Ala Ser 70 75 80 85 aag gaa gat atc atc gcg cag ttg cag gct gca ggt aaa cat aat cag 403 Lys Glu Asp Ile Ile Ala Gln Leu Gln Ala Ala Gly Lys His Asn Gln 90 95 100 gct tcc atg atg gaa gac atg aac ctt gtt cca ggc tca ggc att gat 451 Ala Ser Met Met Glu Asp Met Asn Leu Val Pro Gly Ser Gly Ile Asp 105 110 115 ttt gaa aaa tta gcc atg atc ctc gga ctg gtg atc ggt gct tat ctc 499 Phe Glu Lys Leu Ala Met Ile Leu Gly Leu Val Ile Gly Ala Tyr Leu 120 125 130 atc ggt agc ctg ttg tcg ttg ttc cag gcg cgg atg ctc aac cgc atc 547 Ile Gly Ser Leu Leu Ser Leu Phe Gln Ala Arg Met Leu Asn Arg Ile 135 140 145 gtg caa agt gcc atg cac cgg ctg cgc atg gag gtg gag gaa aaa atc 595 Val Gln Ser Ala Met His Arg Leu Arg Met Glu Val Glu Glu Lys Ile 150 155 160 165 cac cgc cta ccg ctg agc tat ttc gat tcc atc aaa cgt ggt gat ctg 643 His Arg Leu Pro Leu Ser Tyr Phe Asp Ser Ile Lys Arg Gly Asp Leu 170 175 180 ctt agc cgt gtg acc aac gat gtg gat aat atc ggt caa tcc ctg caa 691 Leu Ser Arg Val Thr Asn Asp Val Asp Asn Ile Gly Gln Ser Leu Gln 185 190 195 caa acc ttg tca cag gcg atc act tcc cta ctg acc gtc atc ggt gtg 739 Gln Thr Leu Ser Gln Ala Ile Thr Ser Leu Leu Thr Val Ile Gly Val 200 205 210 ttg gtg atg atg ttt atc atc tcc cca ctg ctc gca ctc gtg gcg ctg 787 Leu Val Met Met Phe Ile Ile Ser Pro Leu Leu Ala Leu Val Ala Leu 215 220 225 gta tcc att ccg gtc acc atc gtg gtc act gtg gtg gtt gcg agc cgt 835 Val Ser Ile Pro Val Thr Ile Val Val Thr Val Val Val Ala Ser Arg 230 235 240 245 tcc cag aaa ctc ttt gcg gaa cag tgg aag cag acc ggt att ttg aat 883 Ser Gln Lys Leu Phe Ala Glu Gln Trp Lys Gln Thr Gly Ile Leu Asn 250 255 260 gcg cgc ctg gag gaa acc tac tct ggc cac gcc gtg gtt aag gtt ttc 931 Ala Arg Leu Glu Glu Thr Tyr Ser Gly His Ala Val Val Lys Val Phe 265 270 275 gga cac caa aag gat gtt caa gaa gca ttc gag gaa gaa aat caa gct 979 Gly His Gln Lys Asp Val Gln Glu Ala Phe Glu Glu Glu Asn Gln Ala 280 285 290 tgt gta taaggccagc tttggtgccc agt 1008 Cys Val 295 <210> 62 <211> 295 <212> PRT <213> Corynebacterium glutamicum <400> 62 Met Ser Asn Thr Ala Gly Pro Arg Gly Arg Ser His Gln Ala Asp Ala 1 5 10 15 Ala Pro Asn Gln Lys Ala Gln Asn Phe Gly Pro Ser Ala Lys Arg Leu 20 25 30 Phe Gly Ile Leu Gly His Asp Arg Asn Thr Leu Ile Phe Val Ile Phe 35 40 45 Leu Ala Val Leu Ser Val Gly Leu Thr Val Leu Gly Pro Trp Leu Leu 50 55 60 Gly Lys Ala Thr Asn Val Val Phe Glu Gly Phe Leu Ser Lys Arg Met 65 70 75 80 Pro Ala Gly Ala Ser Lys Glu Asp Ile Ile Ala Gln Leu Gln Ala Ala 85 90 95 Gly Lys His Asn Gln Ala Ser Met Met Glu Asp Met Asn Leu Val Pro 100 105 110 Gly Ser Gly Ile Asp Phe Glu Lys Leu Ala Met Ile Leu Gly Leu Val 115 120 125 Ile Gly Ala Tyr Leu Ile Gly Ser Leu Leu Ser Leu Phe Gln Ala Arg 130 135 140 Met Leu Asn Arg Ile Val Gln Ser Ala Met His Arg Leu Arg Met Glu 145 150 155 160 Val Glu Glu Lys Ile His Arg Leu Pro Leu Ser Tyr Phe Asp Ser Ile 165 170 175 Lys Arg Gly Asp Leu Leu Ser Arg Val Thr Asn Asp Val Asp Asn Ile 180 185 190 Gly Gln Ser Leu Gln Gln Thr Leu Ser Gln Ala Ile Thr Ser Leu Leu 195 200 205 Thr Val Ile Gly Val Leu Val Met Met Phe Ile Ile Ser Pro Leu Leu 210 215 220 Ala Leu Val Ala Leu Val Ser Ile Pro Val Thr Ile Val Val Thr Val 225 230 235 240 Val Val Ala Ser Arg Ser Gln Lys Leu Phe Ala Glu Gln Trp Lys Gln 245 250 255 Thr Gly Ile Leu Asn Ala Arg Leu Glu Glu Thr Tyr Ser Gly His Ala 260 265 270 Val Val Lys Val Phe Gly His Gln Lys Asp Val Gln Glu Ala Phe Glu 275 280 285 Glu Glu Asn Gln Ala Cys Val 290 295 <210> 63 <211> 426 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(426) <223> RXC00861 <400> 63 atg gct cct cac aag gtc atg ctg att acc act ggt act cag ggt gag 48 Met Ala Pro His Lys Val Met Leu Ile Thr Thr Gly Thr Gln Gly Glu 1 5 10 15 cct atg gct gcg ctg tct cgc atg gcg cgt cgt gag cac cga cag atc 96 Pro Met Ala Ala Leu Ser Arg Met Ala Arg Arg Glu His Arg Gln Ile 20 25 30 act gtc cgt gat gga gac ttg att atc ctt tct tcc tcc ctg gtt cca 144 Thr Val Arg Asp Gly Asp Leu Ile Ile Leu Ser Ser Ser Leu Val Pro 35 40 45 ggt aac gaa gaa gca gtg ttc ggt gtc atc aac atg ctg gct cag atc 192 Gly Asn Glu Glu Ala Val Phe Gly Val Ile Asn Met Leu Ala Gln Ile 50 55 60 ggt gca act gtt gtt acc ggt cgc gac gcc aag gtg cac acc tcg ggc 240 Gly Ala Thr Val Val Thr Gly Arg Asp Ala Lys Val His Thr Ser Gly 65 70 75 80 cac ggc tac tcc gga gag ctg ttg ttc ttg tac aac gcc gct cgt ccg 288 His Gly Tyr Ser Gly Glu Leu Leu Phe Leu Tyr Asn Ala Ala Arg Pro 85 90 95 aag aac gct atg cct gtc cac ggc gag tgg cgc cac ctg cgc gcc aac 336 Lys Asn Ala Met Pro Val His Gly Glu Trp Arg His Leu Arg Ala Asn 100 105 110 aag gaa ctg gct atc tcc act ggt gtt aac cgc gac aac gtt gtg ctt 384 Lys Glu Leu Ala Ile Ser Thr Gly Val Asn Arg Asp Asn Val Val Leu 115 120 125 gca caa aac ggt gtt gtg gtt gat atg gtc aac ggt cgc gca 426 Ala Gln Asn Gly Val Val Val Asp Met Val Asn Gly Arg Ala 130 135 140 <210> 64 <211> 142 <212> PRT <213> Corynebacterium glutamicum <400> 64 Met Ala Pro His Lys Val Met Leu Ile Thr Thr Gly Thr Gln Gly Glu 1 5 10 15 Pro Met Ala Ala Leu Ser Arg Met Ala Arg Arg Glu His Arg Gln Ile 20 25 30 Thr Val Arg Asp Gly Asp Leu Ile Ile Leu Ser Ser Ser Leu Val Pro 35 40 45 Gly Asn Glu Glu Ala Val Phe Gly Val Ile Asn Met Leu Ala Gln Ile 50 55 60 Gly Ala Thr Val Val Thr Gly Arg Asp Ala Lys Val His Thr Ser Gly 65 70 75 80 His Gly Tyr Ser Gly Glu Leu Leu Phe Leu Tyr Asn Ala Ala Arg Pro 85 90 95 Lys Asn Ala Met Pro Val His Gly Glu Trp Arg His Leu Arg Ala Asn 100 105 110 Lys Glu Leu Ala Ile Ser Thr Gly Val Asn Arg Asp Asn Val Val Leu 115 120 125 Ala Gln Asn Gly Val Val Val Asp Met Val Asn Gly Arg Ala 130 135 140 <210> 65 <211> 1066 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1066) <223> RXC00866 <400> 65 gcatcaacgt aggagatcct cgacttccaa ttatggctcc aaatgagcag gaacttgagg 60 ctctccgaga agacatgaaa aaagctggag ttctataaat atg aat gat tcc cga 115 Met Asn Asp Ser Arg 1 5 aat cgc ggc cgg aag gtt acc cgc aag gcg ggc cca cca gaa gct ggt 163 Asn Arg Gly Arg Lys Val Thr Arg Lys Ala Gly Pro Pro Glu Ala Gly 10 15 20 cag gaa aac cat ctg gat acc cct gtc ttt cag gca cca gat gct tcc 211 Gln Glu Asn His Leu Asp Thr Pro Val Phe Gln Ala Pro Asp Ala Ser 25 30 35 tct aac cag agc gct gta aaa gct gag acc gcc gga aac gac aat cgg 259 Ser Asn Gln Ser Ala Val Lys Ala Glu Thr Ala Gly Asn Asp Asn Arg 40 45 50 gat gct gcg caa ggt gct caa gga tcc caa gat tct cag ggt tcc cag 307 Asp Ala Ala Gln Gly Ala Gln Gly Ser Gln Asp Ser Gln Gly Ser Gln 55 60 65 aac gct caa ggt tcc cag aac cgc gag tcc gga aac aac aac cgc aac 355 Asn Ala Gln Gly Ser Gln Asn Arg Glu Ser Gly Asn Asn Asn Arg Asn 70 75 80 85 cgt tcc aac aac aac cgt cgc ggt ggt cgt gga cgt cgt gga tcc gga 403 Arg Ser Asn Asn Asn Arg Arg Gly Gly Arg Gly Arg Arg Gly Ser Gly 90 95 100 aac gcc aat gag ggc gcg aac aac aac agc ggt aac cag aac cgt cag 451 Asn Ala Asn Glu Gly Ala Asn Asn Asn Ser Gly Asn Gln Asn Arg Gln 105 110 115 ggc gga aac cgt ggc aac cgc ggt ggc gga cgc cga aac gtt gtt aag 499 Gly Gly Asn Arg Gly Asn Arg Gly Gly Gly Arg Arg Asn Val Val Lys 120 125 130 tcg atg cag ggt gcg gat ctg acc cag cgc ctg cca gag cca cca aag 547 Ser Met Gln Gly Ala Asp Leu Thr Gln Arg Leu Pro Glu Pro Pro Lys 135 140 145 gca ccg gca aac ggt ctg cgt att tac gca ctt ggt ggc att tcc gaa 595 Ala Pro Ala Asn Gly Leu Arg Ile Tyr Ala Leu Gly Gly Ile Ser Glu 150 155 160 165 atc ggt cgc aac atg acc gtg ttt gag tac aac aac cgt ctg ctc atc 643 Ile Gly Arg Asn Met Thr Val Phe Glu Tyr Asn Asn Arg Leu Leu Ile 170 175 180 gtg gac tgt ggt gtg ctc ttc cca tct tca ggt gag cca ggc gtt gac 691 Val Asp Cys Gly Val Leu Phe Pro Ser Ser Gly Glu Pro Gly Val Asp 185 190 195 ctg att ctt cct gac ttc ggc cca att gag gat cac ctg cac cgc gtc 739 Leu Ile Leu Pro Asp Phe Gly Pro Ile Glu Asp His Leu His Arg Val 200 205 210 gat gca ttg gtg gtt act cac gga cac gaa gac cac att ggt gct att 787 Asp Ala Leu Val Val Thr His Gly His Glu Asp His Ile Gly Ala Ile 215 220 225 ccc tgg ctg ctg aag ctg cgc aac gat atc cca atc ttg gca tcc cgt 835 Pro Trp Leu Leu Lys Leu Arg Asn Asp Ile Pro Ile Leu Ala Ser Arg 230 235 240 245 ttc acc ttg gct ctg att gca gct aag tgt aag gaa cac cgt cag cgt 883 Phe Thr Leu Ala Leu Ile Ala Ala Lys Cys Lys Glu His Arg Gln Arg 250 255 260 ccg aag ctg atc gag gtc aac gag cag tcc aat gag gac cgc gga ccg 931 Pro Lys Leu Ile Glu Val Asn Glu Gln Ser Asn Glu Asp Arg Gly Pro 265 270 275 ttc aac att cgc ttc tgg gct gtt aac cac tcc atc cca gac tgc ctt 979 Phe Asn Ile Arg Phe Trp Ala Val Asn His Ser Ile Pro Asp Cys Leu 280 285 290 ggt ctt gct atc aag act cct gct ggt ttg gtc atc cac acc ggt gac 1027 Gly Leu Ala Ile Lys Thr Pro Ala Gly Leu Val Ile His Thr Gly Asp 295 300 305 atc aag ctg gat cag act cct cct gat gga cgc cca act 1066 Ile Lys Leu Asp Gln Thr Pro Pro Asp Gly Arg Pro Thr 310 315 320 <210> 66 <211> 322 <212> PRT <213> Corynebacterium glutamicum <400> 66 Met Asn Asp Ser Arg Asn Arg Gly Arg Lys Val Thr Arg Lys Ala Gly 1 5 10 15 Pro Pro Glu Ala Gly Gln Glu Asn His Leu Asp Thr Pro Val Phe Gln 20 25 30 Ala Pro Asp Ala Ser Ser Asn Gln Ser Ala Val Lys Ala Glu Thr Ala 35 40 45 Gly Asn Asp Asn Arg Asp Ala Ala Gln Gly Ala Gln Gly Ser Gln Asp 50 55 60 Ser Gln Gly Ser Gln Asn Ala Gln Gly Ser Gln Asn Arg Glu Ser Gly 65 70 75 80 Asn Asn Asn Arg Asn Arg Ser Asn Asn Asn Arg Arg Gly Gly Arg Gly 85 90 95 Arg Arg Gly Ser Gly Asn Ala Asn Glu Gly Ala Asn Asn Asn Ser Gly 100 105 110 Asn Gln Asn Arg Gln Gly Gly Asn Arg Gly Asn Arg Gly Gly Gly Arg 115 120 125 Arg Asn Val Val Lys Ser Met Gln Gly Ala Asp Leu Thr Gln Arg Leu 130 135 140 Pro Glu Pro Pro Lys Ala Pro Ala Asn Gly Leu Arg Ile Tyr Ala Leu 145 150 155 160 Gly Gly Ile Ser Glu Ile Gly Arg Asn Met Thr Val Phe Glu Tyr Asn 165 170 175 Asn Arg Leu Leu Ile Val Asp Cys Gly Val Leu Phe Pro Ser Ser Gly 180 185 190 Glu Pro Gly Val Asp Leu Ile Leu Pro Asp Phe Gly Pro Ile Glu Asp 195 200 205 His Leu His Arg Val Asp Ala Leu Val Val Thr His Gly His Glu Asp 210 215 220 His Ile Gly Ala Ile Pro Trp Leu Leu Lys Leu Arg Asn Asp Ile Pro 225 230 235 240 Ile Leu Ala Ser Arg Phe Thr Leu Ala Leu Ile Ala Ala Lys Cys Lys 245 250 255 Glu His Arg Gln Arg Pro Lys Leu Ile Glu Val Asn Glu Gln Ser Asn 260 265 270 Glu Asp Arg Gly Pro Phe Asn Ile Arg Phe Trp Ala Val Asn His Ser 275 280 285 Ile Pro Asp Cys Leu Gly Leu Ala Ile Lys Thr Pro Ala Gly Leu Val 290 295 300 Ile His Thr Gly Asp Ile Lys Leu Asp Gln Thr Pro Pro Asp Gly Arg 305 310 315 320 Pro Thr <210> 67 <211> 1527 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1504) <223> RXC02095 <400> 67 ctctcttggt cctctcccca cccattttta agtactcaag acccttccaa cagaaaggat 60 tactccccca acaggctcaa aaatactgaa aggctcacgc atg aaa act gag caa 115 Met Lys Thr Glu Gln 1 5 tcc caa aaa gca caa tta gcc cct aag aaa gca cct gaa aag cca caa 163 Ser Gln Lys Ala Gln Leu Ala Pro Lys Lys Ala Pro Glu Lys Pro Gln 10 15 20 cgc atc cgc caa ctt att tcc gtg gcg tgg cag cga cct tgg ctc acc 211 Arg Ile Arg Gln Leu Ile Ser Val Ala Trp Gln Arg Pro Trp Leu Thr 25 30 35 tca ttc acc gta atc agc gct tta gct gca acg ttg ttt gaa ctt aca 259 Ser Phe Thr Val Ile Ser Ala Leu Ala Ala Thr Leu Phe Glu Leu Thr 40 45 50 ctt cct ctt ttg acc ggt ggc gcc atc gat atc gcg ctc gga aat acc 307 Leu Pro Leu Leu Thr Gly Gly Ala Ile Asp Ile Ala Leu Gly Asn Thr 55 60 65 gga gat act tta acc act gac ctg ctg gac cgg ttc act ccg agt gga 355 Gly Asp Thr Leu Thr Thr Asp Leu Leu Asp Arg Phe Thr Pro Ser Gly 70 75 80 85 tta agc gtg ttg acc agc gtc att gcc ctt atc gtg ctt ctc gcg ttg 403 Leu Ser Val Leu Thr Ser Val Ile Ala Leu Ile Val Leu Leu Ala Leu 90 95 100 ctt cgc tat gcc agt caa ttt gga cgg cga tac acc gca ggc aag ctc 451 Leu Arg Tyr Ala Ser Gln Phe Gly Arg Arg Tyr Thr Ala Gly Lys Leu 105 110 115 agc atg ggg gta cag cat gat gtc cgg ctt aaa acg atg cgc tca ttg 499 Ser Met Gly Val Gln His Asp Val Arg Leu Lys Thr Met Arg Ser Leu 120 125 130 cag aac ctc gat ggg cca ggt cag gac tct att cgc aca ggc caa gta 547 Gln Asn Leu Asp Gly Pro Gly Gln Asp Ser Ile Arg Thr Gly Gln Val 135 140 145 gtc agt cgg tcc att tcg gat atc aac atg gtg caa agc ctt gtg gcg 595 Val Ser Arg Ser Ile Ser Asp Ile Asn Met Val Gln Ser Leu Val Ala 150 155 160 165 atg ttg ccg atg ttg atc gga aat gtg gtc aag ctt gtg ctc act ttg 643 Met Leu Pro Met Leu Ile Gly Asn Val Val Lys Leu Val Leu Thr Leu 170 175 180 gtg atc atg ctg gct att tcc ccg ccg ctg acc atc atc gct gca gtg 691 Val Ile Met Leu Ala Ile Ser Pro Pro Leu Thr Ile Ile Ala Ala Val 185 190 195 ttg gtg cct ttg ctg ttg tgg gcc gtg gcc tat tcg cga aaa gcg ctt 739 Leu Val Pro Leu Leu Leu Trp Ala Val Ala Tyr Ser Arg Lys Ala Leu 200 205 210 ttt gcg tcc acg tgg tcg gcc cag caa aag gct gcg gat ctg acc act 787 Phe Ala Ser Thr Trp Ser Ala Gln Gln Lys Ala Ala Asp Leu Thr Thr 215 220 225 cat gtg gaa gaa act gtc acg ggt atc cgc gtg gtc aag gca ttt gcg 835 His Val Glu Glu Thr Val Thr Gly Ile Arg Val Val Lys Ala Phe Ala 230 235 240 245 cag gaa gac cgc gag acc gac aaa ttg gat ctc acc gca cgt gag tta 883 Gln Glu Asp Arg Glu Thr Asp Lys Leu Asp Leu Thr Ala Arg Glu Leu 250 255 260 ttt gcc cag cgc atg cgc act gca cgt ctg acg gca aag ttc atc ccc 931 Phe Ala Gln Arg Met Arg Thr Ala Arg Leu Thr Ala Lys Phe Ile Pro 265 270 275 atg gtt gag cag ctt ccg cag ctt gct ttg gtg gtc aac att gtt ggc 979 Met Val Glu Gln Leu Pro Gln Leu Ala Leu Val Val Asn Ile Val Gly 280 285 290 ggt ggc tat ttg gcc atg act ggt cac atc acg gtg ggc acg ttt gtg 1027 Gly Gly Tyr Leu Ala Met Thr Gly His Ile Thr Val Gly Thr Phe Val 295 300 305 gcg ttt tct tcc tat ctc act agc ttg tcg gcg gtg gct agg tcc ctg 1075 Ala Phe Ser Ser Tyr Leu Thr Ser Leu Ser Ala Val Ala Arg Ser Leu 310 315 320 325 tcg ggc atg ctc atg cgc gtg cag ttg gcg ctg tct tct gtg gag cgc 1123 Ser Gly Met Leu Met Arg Val Gln Leu Ala Leu Ser Ser Val Glu Arg 330 335 340 atc ttt gaa gtc att gat ctt cag cct gaa cgc acc gat cct gca cac 1171 Ile Phe Glu Val Ile Asp Leu Gln Pro Glu Arg Thr Asp Pro Ala His 345 350 355 ccc ctg tca ctt ccc gac act ccc ctg ggt ctg tcg ttc aac aac gta 1219 Pro Leu Ser Leu Pro Asp Thr Pro Leu Gly Leu Ser Phe Asn Asn Val 360 365 370 gat ttc cgt ggg att ctc aac ggt ttt gag ctg ggt gtt cag gcc ggt 1267 Asp Phe Arg Gly Ile Leu Asn Gly Phe Glu Leu Gly Val Gln Ala Gly 375 380 385 gaa acc gtt gtg ttg gtg ggc cct cca ggt tca ggc aag acc atg gct 1315 Glu Thr Val Val Leu Val Gly Pro Pro Gly Ser Gly Lys Thr Met Ala 390 395 400 405 gtg cag ctt gct gga aac ttt tat caa cca gac agc ggc cac atc gcc 1363 Val Gln Leu Ala Gly Asn Phe Tyr Gln Pro Asp Ser Gly His Ile Ala 410 415 420 ttt gat agc aac ggc cat cgc act cgc ttc gac gac ctc acc cac agc 1411 Phe Asp Ser Asn Gly His Arg Thr Arg Phe Asp Asp Leu Thr His Ser 425 430 435 gat atc cgc agg aat ctc atc gcg gtt ttt gat gag ccg ttc ttg tac 1459 Asp Ile Arg Arg Asn Leu Ile Ala Val Phe Asp Glu Pro Phe Leu Tyr 440 445 450 tcc tcc tcc ata ccg cga gaa cat ctc gat ggg ttt gga tgt cag 1504 Ser Ser Ser Ile Pro Arg Glu His Leu Asp Gly Phe Gly Cys Gln 455 460 465 tgatgagcag atcgaacacg cag 1527 <210> 68 <211> 468 <212> PRT <213> Corynebacterium glutamicum <400> 68 Met Lys Thr Glu Gln Ser Gln Lys Ala Gln Leu Ala Pro Lys Lys Ala 1 5 10 15 Pro Glu Lys Pro Gln Arg Ile Arg Gln Leu Ile Ser Val Ala Trp Gln 20 25 30 Arg Pro Trp Leu Thr Ser Phe Thr Val Ile Ser Ala Leu Ala Ala Thr 35 40 45 Leu Phe Glu Leu Thr Leu Pro Leu Leu Thr Gly Gly Ala Ile Asp Ile 50 55 60 Ala Leu Gly Asn Thr Gly Asp Thr Leu Thr Thr Asp Leu Leu Asp Arg 65 70 75 80 Phe Thr Pro Ser Gly Leu Ser Val Leu Thr Ser Val Ile Ala Leu Ile 85 90 95 Val Leu Leu Ala Leu Leu Arg Tyr Ala Ser Gln Phe Gly Arg Arg Tyr 100 105 110 Thr Ala Gly Lys Leu Ser Met Gly Val Gln His Asp Val Arg Leu Lys 115 120 125 Thr Met Arg Ser Leu Gln Asn Leu Asp Gly Pro Gly Gln Asp Ser Ile 130 135 140 Arg Thr Gly Gln Val Val Ser Arg Ser Ile Ser Asp Ile Asn Met Val 145 150 155 160 Gln Ser Leu Val Ala Met Leu Pro Met Leu Ile Gly Asn Val Val Lys 165 170 175 Leu Val Leu Thr Leu Val Ile Met Leu Ala Ile Ser Pro Pro Leu Thr 180 185 190 Ile Ile Ala Ala Val Leu Val Pro Leu Leu Leu Trp Ala Val Ala Tyr 195 200 205 Ser Arg Lys Ala Leu Phe Ala Ser Thr Trp Ser Ala Gln Gln Lys Ala 210 215 220 Ala Asp Leu Thr Thr His Val Glu Glu Thr Val Thr Gly Ile Arg Val 225 230 235 240 Val Lys Ala Phe Ala Gln Glu Asp Arg Glu Thr Asp Lys Leu Asp Leu 245 250 255 Thr Ala Arg Glu Leu Phe Ala Gln Arg Met Arg Thr Ala Arg Leu Thr 260 265 270 Ala Lys Phe Ile Pro Met Val Glu Gln Leu Pro Gln Leu Ala Leu Val 275 280 285 Val Asn Ile Val Gly Gly Gly Tyr Leu Ala Met Thr Gly His Ile Thr 290 295 300 Val Gly Thr Phe Val Ala Phe Ser Ser Tyr Leu Thr Ser Leu Ser Ala 305 310 315 320 Val Ala Arg Ser Leu Ser Gly Met Leu Met Arg Val Gln Leu Ala Leu 325 330 335 Ser Ser Val Glu Arg Ile Phe Glu Val Ile Asp Leu Gln Pro Glu Arg 340 345 350 Thr Asp Pro Ala His Pro Leu Ser Leu Pro Asp Thr Pro Leu Gly Leu 355 360 365 Ser Phe Asn Asn Val Asp Phe Arg Gly Ile Leu Asn Gly Phe Glu Leu 370 375 380 Gly Val Gln Ala Gly Glu Thr Val Val Leu Val Gly Pro Pro Gly Ser 385 390 395 400 Gly Lys Thr Met Ala Val Gln Leu Ala Gly Asn Phe Tyr Gln Pro Asp 405 410 415 Ser Gly His Ile Ala Phe Asp Ser Asn Gly His Arg Thr Arg Phe Asp 420 425 430 Asp Leu Thr His Ser Asp Ile Arg Arg Asn Leu Ile Ala Val Phe Asp 435 440 445 Glu Pro Phe Leu Tyr Ser Ser Ser Ile Pro Arg Glu His Leu Asp Gly 450 455 460 Phe Gly Cys Gln 465 <210> 69 <211> 295 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (84)..(272) <223> RXC03185 <220> <221> misc_feature <222> 57 <223> n = a, c, g, or t <400> 69 agcgcccaac cgttcagacc agcggtttct ctgaggatgc aaagtccatg atgggtnagg 60 tcactgagct gtccgaaacc acc atg aat gat ctt gca gct gaa ggt gaa aac 113 Met Asn Asp Leu Ala Ala Glu Gly Glu Asn 1 5 10 gat cct tac cgc atg gtt cag cag ctg cgc cgc aag ctc tct cgc ttc 161 Asp Pro Tyr Arg Met Val Gln Gln Leu Arg Arg Lys Leu Ser Arg Phe 15 20 25 gtc gag cag aag tgg aag cgc cag ccg gtc atc atg cca acc gtc att 209 Val Glu Gln Lys Trp Lys Arg Gln Pro Val Ile Met Pro Thr Val Ile 30 35 40 ccg atg act gcg gaa acc acg cac atc ggt gac gat gag gtt cgc gct 257 Pro Met Thr Ala Glu Thr Thr His Ile Gly Asp Asp Glu Val Arg Ala 45 50 55 tca cgc gag tcc ctg taaaagcatt tcgcttttcg acg 295 Ser Arg Glu Ser Leu 60 <210> 70 <211> 63 <212> PRT <213> Corynebacterium glutamicum <400> 70 Met Asn Asp Leu Ala Ala Glu Gly Glu Asn Asp Pro Tyr Arg Met Val 1 5 10 15 Gln Gln Leu Arg Arg Lys Leu Ser Arg Phe Val Glu Gln Lys Trp Lys 20 25 30 Arg Gln Pro Val Ile Met Pro Thr Val Ile Pro Met Thr Ala Glu Thr 35 40 45 Thr His Ile Gly Asp Asp Glu Val Arg Ala Ser Arg Glu Ser Leu 50 55 60 <210> 71 <211> 4653 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(4630) <223> RXN00367 <400> 71 atcgaaagta acccttttgt tacttgcgtt gcaggtagtg tccctgattt tcttattatc 60 gaacgattga tagaaacagg attaaagtga ggtatcccgc atg aaa cca caa gga 115 Met Lys Pro Gln Gly 1 5 ctc tac aac cct gcg cat gaa cat gac gcc tgc ggt gtg gcg ttt att 163 Leu Tyr Asn Pro Ala His Glu His Asp Ala Cys Gly Val Ala Phe Ile 10 15 20 gcg gat atc cac ggt cga ccc agc cgc agc att gtt gat cgt gca ctt 211 Ala Asp Ile His Gly Arg Pro Ser Arg Ser Ile Val Asp Arg Ala Leu 25 30 35 gag gcg ctt cgc aac att gac cac cga ggt gcc gcc ggt gca gag aag 259 Glu Ala Leu Arg Asn Ile Asp His Arg Gly Ala Ala Gly Ala Glu Lys 40 45 50 aac act ggc gat ggt gcg ggc atc ctc atg cag att ccg gac ggc ttt 307 Asn Thr Gly Asp Gly Ala Gly Ile Leu Met Gln Ile Pro Asp Gly Phe 55 60 65 tat cgt gaa gta tct ggc att gag ctt cct gag gca ggg gag tat gcc 355 Tyr Arg Glu Val Ser Gly Ile Glu Leu Pro Glu Ala Gly Glu Tyr Ala 70 75 80 85 act ggt att gcg ttc ttg cct cgc ggt cgc atg gcg atg atg gat gct 403 Thr Gly Ile Ala Phe Leu Pro Arg Gly Arg Met Ala Met Met Asp Ala 90 95 100 cag aag gaa att gag cgc atc gca aag caa gaa ggt gcc gat gtg ctt 451 Gln Lys Glu Ile Glu Arg Ile Ala Lys Gln Glu Gly Ala Asp Val Leu 105 110 115 ggt tgg cgc atg gtt cct ttt gat tct cgt gat ttg ggt tcc atg gct 499 Gly Trp Arg Met Val Pro Phe Asp Ser Arg Asp Leu Gly Ser Met Ala 120 125 130 gag gag gcg atg cct agt ttc gcg cag att ttc ctt act gtg cct gga 547 Glu Glu Ala Met Pro Ser Phe Ala Gln Ile Phe Leu Thr Val Pro Gly 135 140 145 aaa tct ggt gaa gat ctt gac cgt gtg atg ttc ttt atc cgt aag cgt 595 Lys Ser Gly Glu Asp Leu Asp Arg Val Met Phe Phe Ile Arg Lys Arg 150 155 160 165 tgt gag cgt gag ctg ggc acc acc aat ggt cgc gat acg gtg tat ttc 643 Cys Glu Arg Glu Leu Gly Thr Thr Asn Gly Arg Asp Thr Val Tyr Phe 170 175 180 ccg tcg cta tct tca cgc acc atc att tac aaa ggc atg ttg acc act 691 Pro Ser Leu Ser Ser Arg Thr Ile Ile Tyr Lys Gly Met Leu Thr Thr 185 190 195 ctg cag ctt gag ggc ttc ttt gag gat ctg ggt gat gct cgc ctg gag 739 Leu Gln Leu Glu Gly Phe Phe Glu Asp Leu Gly Asp Ala Arg Leu Glu 200 205 210 tcg gcc att gct att gtg cac tcg cgt ttc tcc acg aac act ttc cca 787 Ser Ala Ile Ala Ile Val His Ser Arg Phe Ser Thr Asn Thr Phe Pro 215 220 225 agc tgg ccg ctg gcg cac ccg tac cgt ttc gtt gcc cac aac ggt gag 835 Ser Trp Pro Leu Ala His Pro Tyr Arg Phe Val Ala His Asn Gly Glu 230 235 240 245 atc aac act gtg cgt ggc aat gaa aac tgg atg cgc gcc cgc gag gcg 883 Ile Asn Thr Val Arg Gly Asn Glu Asn Trp Met Arg Ala Arg Glu Ala 250 255 260 ctt atc aaa aac gac aag ctg ggc aat ttg agc agc gtg ctg cct atc 931 Leu Ile Lys Asn Asp Lys Leu Gly Asn Leu Ser Ser Val Leu Pro Ile 265 270 275 tgc acc ccg gag ggc tcg gat acc gcg cgt ttc gac gag gct ttg gag 979 Cys Thr Pro Glu Gly Ser Asp Thr Ala Arg Phe Asp Glu Ala Leu Glu 280 285 290 ctt ttg cac ctg ggc gga tac tca ctt ccg cat gct gtt gcg atg atg 1027 Leu Leu His Leu Gly Gly Tyr Ser Leu Pro His Ala Val Ala Met Met 295 300 305 atc cct cag gcg tgg gaa cac aac aag acg ctg agc cct gag ctg cgt 1075 Ile Pro Gln Ala Trp Glu His Asn Lys Thr Leu Ser Pro Glu Leu Arg 310 315 320 325 gat ttc tac gaa tac cac tct tgt ctg atg gag cca tgg gat ggt cct 1123 Asp Phe Tyr Glu Tyr His Ser Cys Leu Met Glu Pro Trp Asp Gly Pro 330 335 340 gca gcg ctg gca ttt act gac ggt cgt ttt gtg ggt gcc gtg ctg gac 1171 Ala Ala Leu Ala Phe Thr Asp Gly Arg Phe Val Gly Ala Val Leu Asp 345 350 355 cgt aat ggc ctg cga cct ggg cga atc acc att act gat tcg ggt ttg 1219 Arg Asn Gly Leu Arg Pro Gly Arg Ile Thr Ile Thr Asp Ser Gly Leu 360 365 370 gtt gtg atg gct tct gaa tcg gga gtg ttg gac ttg agg gag gag agc 1267 Val Val Met Ala Ser Glu Ser Gly Val Leu Asp Leu Arg Glu Glu Ser 375 380 385 gtc gta aag cgt act cgc gta cag cct gga cgc atg ttc ctt gtt gac 1315 Val Val Lys Arg Thr Arg Val Gln Pro Gly Arg Met Phe Leu Val Asp 390 395 400 405 act gcc gag ggc cgc atc gtt gaa gac gag gaa atc aag cag aaa tta 1363 Thr Ala Glu Gly Arg Ile Val Glu Asp Glu Glu Ile Lys Gln Lys Leu 410 415 420 agc gaa gcg cag cca tat ggt gag tgg att cgc gat aat ttt gtg cat 1411 Ser Glu Ala Gln Pro Tyr Gly Glu Trp Ile Arg Asp Asn Phe Val His 425 430 435 ctg gat cgt ctg cct cag aca cgc tac aac tac atg gcg cac tct cgt 1459 Leu Asp Arg Leu Pro Gln Thr Arg Tyr Asn Tyr Met Ala His Ser Arg 440 445 450 gct gtg ttg cgt cag cgt gtt ttc gga atc act gaa gaa gat gtg gat 1507 Ala Val Leu Arg Gln Arg Val Phe Gly Ile Thr Glu Glu Asp Val Asp 455 460 465 ttg ttg ctg ctg ccg atg gcc cgc cag ggt gct gag gcg att ggt tcc 1555 Leu Leu Leu Leu Pro Met Ala Arg Gln Gly Ala Glu Ala Ile Gly Ser 470 475 480 485 atg ggt tcg gat acg cca att gcg gcg cta tcc cag cga cca cgc atg 1603 Met Gly Ser Asp Thr Pro Ile Ala Ala Leu Ser Gln Arg Pro Arg Met 490 495 500 ctt tat gat ttc ttc gcg cag cgc ttt gct cag gtg aca aac cca ccg 1651 Leu Tyr Asp Phe Phe Ala Gln Arg Phe Ala Gln Val Thr Asn Pro Pro 505 510 515 ttg gac tct atc cgc gaa aag cct gtg acc agc atg ttc act ttg ttg 1699 Leu Asp Ser Ile Arg Glu Lys Pro Val Thr Ser Met Phe Thr Leu Leu 520 525 530 ggt gcg cag tct gac gtg ctc aat ccg ggt cct gat gcg gcg cga cgt 1747 Gly Ala Gln Ser Asp Val Leu Asn Pro Gly Pro Asp Ala Ala Arg Arg 535 540 545 atc cgt ttg gaa tcg ccg atc att gat aac cat gag ctg gcc acc ttg 1795 Ile Arg Leu Glu Ser Pro Ile Ile Asp Asn His Glu Leu Ala Thr Leu 550 555 560 565 atc aat gcc aac gcg cat ggt gag tgg gat tcc ttt ggt gct gct gta 1843 Ile Asn Ala Asn Ala His Gly Glu Trp Asp Ser Phe Gly Ala Ala Val 570 575 580 att tct ggt ttg tac cca gtg gct cac cat ggt gcc ggc atg aag gct 1891 Ile Ser Gly Leu Tyr Pro Val Ala His His Gly Ala Gly Met Lys Ala 585 590 595 gcg att gct cgt gtg cgc cgc gag gtt tct gaa gca atc cgc aat ggc 1939 Ala Ile Ala Arg Val Arg Arg Glu Val Ser Glu Ala Ile Arg Asn Gly 600 605 610 aag acg ttg atc gtg ctg tcg gat cgt gaa tct gat gag cgc atg gca 1987 Lys Thr Leu Ile Val Leu Ser Asp Arg Glu Ser Asp Glu Arg Met Ala 615 620 625 cct atc cct gcg ctg ctg ctg act tcc gct gtg cat cag tac ttg gtg 2035 Pro Ile Pro Ala Leu Leu Leu Thr Ser Ala Val His Gln Tyr Leu Val 630 635 640 645 cag caa cgt acc cgt acc cag tgc tcc ctg gtg gtg gaa tcc ggc gat 2083 Gln Gln Arg Thr Arg Thr Gln Cys Ser Leu Val Val Glu Ser Gly Asp 650 655 660 gcc cgc gag gtt cat cac ctg gcg atg ctc att ggt ttt ggt gcc gat 2131 Ala Arg Glu Val His His Leu Ala Met Leu Ile Gly Phe Gly Ala Asp 665 670 675 gcg atc aac ccg tac atg gca ttt gaa acc atc gat gag ctg cgc atg 2179 Ala Ile Asn Pro Tyr Met Ala Phe Glu Thr Ile Asp Glu Leu Arg Met 680 685 690 aag ggt cag ttg ggt gat ctt tct ttg gat gag gca tcc cga aac tac 2227 Lys Gly Gln Leu Gly Asp Leu Ser Leu Asp Glu Ala Ser Arg Asn Tyr 695 700 705 atc aag gca gcc acc act ggt gtg ctg aag gtg atg tcc aag atg ggc 2275 Ile Lys Ala Ala Thr Thr Gly Val Leu Lys Val Met Ser Lys Met Gly 710 715 720 725 att gca acg gtg tct tcg tac cgt ggc gcg cag ctt gcc gat gtc act 2323 Ile Ala Thr Val Ser Ser Tyr Arg Gly Ala Gln Leu Ala Asp Val Thr 730 735 740 ggt ctg cac cag gat ctc ctg gac aac tac ttc ggt ggt att gct tca 2371 Gly Leu His Gln Asp Leu Leu Asp Asn Tyr Phe Gly Gly Ile Ala Ser 745 750 755 cca att tct ggc atc ggt ctg gat gaa gtt gca gct gac gta gaa gct 2419 Pro Ile Ser Gly Ile Gly Leu Asp Glu Val Ala Ala Asp Val Glu Ala 760 765 770 cgt cac cgc agc gca ttt ttg cca cgc cct gaa gag cac gct cac cgt 2467 Arg His Arg Ser Ala Phe Leu Pro Arg Pro Glu Glu His Ala His Arg 775 780 785 gaa ttg gat ttg ggt ggt gaa tac aag tgg cgc cgc gaa ggt gaa tac 2515 Glu Leu Asp Leu Gly Gly Glu Tyr Lys Trp Arg Arg Glu Gly Glu Tyr 790 795 800 805 cac ctg ttc aac cca gaa acc atc ttc aag ctg cag cat gca acg cgt 2563 His Leu Phe Asn Pro Glu Thr Ile Phe Lys Leu Gln His Ala Thr Arg 810 815 820 tct ggc agc tac gag att ttc aag gat tac acc cgc aag gtt gat gat 2611 Ser Gly Ser Tyr Glu Ile Phe Lys Asp Tyr Thr Arg Lys Val Asp Asp 825 830 835 caa tcc act cgc ttg ggt act att cgt gga ctg ttt gag ttc agc acg 2659 Gln Ser Thr Arg Leu Gly Thr Ile Arg Gly Leu Phe Glu Phe Ser Thr 840 845 850 gac cgc aag cca att tcg gtg tct gag gtg gag ccg gtc agt gag atc 2707 Asp Arg Lys Pro Ile Ser Val Ser Glu Val Glu Pro Val Ser Glu Ile 855 860 865 gtg aag cgt ttc tcc act ggt gcg atg tct tat ggc tcg att tct gct 2755 Val Lys Arg Phe Ser Thr Gly Ala Met Ser Tyr Gly Ser Ile Ser Ala 870 875 880 885 gaa gcc cat gag gtc ttg gcc atc gcc atg aac cga ctg ggc ggt atg 2803 Glu Ala His Glu Val Leu Ala Ile Ala Met Asn Arg Leu Gly Gly Met 890 895 900 tcc aac tcc ggc gaa ggt ggc gag gac gcc cgc cga ttt gat gtg gaa 2851 Ser Asn Ser Gly Glu Gly Gly Glu Asp Ala Arg Arg Phe Asp Val Glu 905 910 915 ccc aac ggt gac tgg aag cgc tct gcc att aag cag gtg gcc tcg gga 2899 Pro Asn Gly Asp Trp Lys Arg Ser Ala Ile Lys Gln Val Ala Ser Gly 920 925 930 cgt ttc ggc gtg acc agc cac tac ttg aac aac tgc acc gat att cag 2947 Arg Phe Gly Val Thr Ser His Tyr Leu Asn Asn Cys Thr Asp Ile Gln 935 940 945 atc aag atg gca cag ggc gca aag ccc ggt gaa ggt ggc cag ctg cca 2995 Ile Lys Met Ala Gln Gly Ala Lys Pro Gly Glu Gly Gly Gln Leu Pro 950 955 960 965 cca aac aag gtg tac cca tgg gtt gca gaa gtc cgc atc acc acc cca 3043 Pro Asn Lys Val Tyr Pro Trp Val Ala Glu Val Arg Ile Thr Thr Pro 970 975 980 ggc gtt ggt ctg att tcc cct cca cca cac cac gat att tac tcc att 3091 Gly Val Gly Leu Ile Ser Pro Pro Pro His His Asp Ile Tyr Ser Ile 985 990 995 gag gat ctg gct cag ctg atc cac gac ctg aag aac gct aac cca cgc 3139 Glu Asp Leu Ala Gln Leu Ile His Asp Leu Lys Asn Ala Asn Pro Arg 1000 1005 1010 gca cga atc cac gtg aag cta gtg gca gaa caa ggc gtg ggc acc gtt 3187 Ala Arg Ile His Val Lys Leu Val Ala Glu Gln Gly Val Gly Thr Val 1015 1020 1025 gcc gca ggt gtg tcc aaa gca cac gct gat gtg gtg ctt att tcc ggc 3235 Ala Ala Gly Val Ser Lys Ala His Ala Asp Val Val Leu Ile Ser Gly 1030 1035 1040 1045 cac gat ggc gga act ggc gca tct cct ttg acc tcc ctg aag cat gcc 3283 His Asp Gly Gly Thr Gly Ala Ser Pro Leu Thr Ser Leu Lys His Ala 1050 1055 1060 ggt ggt cca tgg gag ttg ggc ttg gct gaa acc cag caa acg ttg ctg 3331 Gly Gly Pro Trp Glu Leu Gly Leu Ala Glu Thr Gln Gln Thr Leu Leu 1065 1070 1075 ctc aac ggc ctg cgc gat cgt att cgc gtg cag tgc gat ggt cag ctg 3379 Leu Asn Gly Leu Arg Asp Arg Ile Arg Val Gln Cys Asp Gly Gln Leu 1080 1085 1090 aaa act ggc cga gac gtg gtt atc gca gct ctt ctc ggt gcc gaa gaa 3427 Lys Thr Gly Arg Asp Val Val Ile Ala Ala Leu Leu Gly Ala Glu Glu 1095 1100 1105 ttc ggt ttt gcc acc gca ccg ctg gtg gtt gaa ggc tgc atc atg atg 3475 Phe Gly Phe Ala Thr Ala Pro Leu Val Val Glu Gly Cys Ile Met Met 1110 1115 1120 1125 cgc gtc tgc cac ctg gac acc tgc ccg gtg ggt atc gct acc cag aac 3523 Arg Val Cys His Leu Asp Thr Cys Pro Val Gly Ile Ala Thr Gln Asn 1130 1135 1140 ccg gat ttg cgt tcc aag ttc acc ggc aag gct gaa cac gtg gtc aac 3571 Pro Asp Leu Arg Ser Lys Phe Thr Gly Lys Ala Glu His Val Val Asn 1145 1150 1155 ttc ttc acc ttc atc gcc cag gaa gtc cgt gag tac ttg gca cag ctt 3619 Phe Phe Thr Phe Ile Ala Gln Glu Val Arg Glu Tyr Leu Ala Gln Leu 1160 1165 1170 ggt ttc cgc tct att gat gaa gcc gtc gga caa gcc cag gtg ctg cgc 3667 Gly Phe Arg Ser Ile Asp Glu Ala Val Gly Gln Ala Gln Val Leu Arg 1175 1180 1185 aag cgt tcc gga atc cca gct gat tcc cgc gca gca cac ctg gat ttg 3715 Lys Arg Ser Gly Ile Pro Ala Asp Ser Arg Ala Ala His Leu Asp Leu 1190 1195 1200 1205 agc cca att ttc cat cgc cca gaa act cca cac ttc cca act cag gat 3763 Ser Pro Ile Phe His Arg Pro Glu Thr Pro His Phe Pro Thr Gln Asp 1210 1215 1220 gtg cgt tgc acc aag acc cag gaa cac agc cta gaa aaa gcc ctg gac 3811 Val Arg Cys Thr Lys Thr Gln Glu His Ser Leu Glu Lys Ala Leu Asp 1225 1230 1235 aac gca ttt att gat aag gct tcg gac acg atc acc cgt gcc gca gcg 3859 Asn Ala Phe Ile Asp Lys Ala Ser Asp Thr Ile Thr Arg Ala Ala Ala 1240 1245 1250 ggt gtg gaa acc agc att gtt att gat agc tcc atc agc aac gtc aac 3907 Gly Val Glu Thr Ser Ile Val Ile Asp Ser Ser Ile Ser Asn Val Asn 1255 1260 1265 cgt tca gtt ggc acg atg ctg ggt tct gca gtc agc cgc gtg gct ggt 3955 Arg Ser Val Gly Thr Met Leu Gly Ser Ala Val Ser Arg Val Ala Gly 1270 1275 1280 1285 gcc caa ggt ttg cca gac ggc acc atc acc ttg aat ctt caa ggc tgc 4003 Ala Gln Gly Leu Pro Asp Gly Thr Ile Thr Leu Asn Leu Gln Gly Cys 1290 1295 1300 gcc ggt aac tcc ttt ggc gcg ttc atc cca cga ggc atc acc atc aac 4051 Ala Gly Asn Ser Phe Gly Ala Phe Ile Pro Arg Gly Ile Thr Ile Asn 1305 1310 1315 ctc acc ggc gat gcc aat gac ttt gtg ggc aag gga tta tct ggc gga 4099 Leu Thr Gly Asp Ala Asn Asp Phe Val Gly Lys Gly Leu Ser Gly Gly 1320 1325 1330 aag att gtg atc aag cct tcc gct cag gct ccg aag cag ctg aag aac 4147 Lys Ile Val Ile Lys Pro Ser Ala Gln Ala Pro Lys Gln Leu Lys Asn 1335 1340 1345 aat cca aat atc att gcc gga aac gtg ctt gga tac ggc gca acc agt 4195 Asn Pro Asn Ile Ile Ala Gly Asn Val Leu Gly Tyr Gly Ala Thr Ser 1350 1355 1360 1365 ggt gaa ttg ttc att cgt ggc cag gtc ggc gaa cgt ttc tgc gtc cgt 4243 Gly Glu Leu Phe Ile Arg Gly Gln Val Gly Glu Arg Phe Cys Val Arg 1370 1375 1380 aac tct ggc gcc acc gca gtg gtt gaa ggt atc gga aac cac ggt tgt 4291 Asn Ser Gly Ala Thr Ala Val Val Glu Gly Ile Gly Asn His Gly Cys 1385 1390 1395 gag tac atg act ggc ggc cga gtc ctg gtt ttg ggc ccg gtt ggt gag 4339 Glu Tyr Met Thr Gly Gly Arg Val Leu Val Leu Gly Pro Val Gly Glu 1400 1405 1410 aac ttt ggt gcc ggc atg tct ggt ggc att gca tac ctg gct aat tcc 4387 Asn Phe Gly Ala Gly Met Ser Gly Gly Ile Ala Tyr Leu Ala Asn Ser 1415 1420 1425 ccg gac cta aac cag aag atc aat ggc gaa ttg gtg gat gtt gtt cca 4435 Pro Asp Leu Asn Gln Lys Ile Asn Gly Glu Leu Val Asp Val Val Pro 1430 1435 1440 1445 ctg agc gct gac gat ctg acg tgg gct gat gag ctc att gct cgc cac 4483 Leu Ser Ala Asp Asp Leu Thr Trp Ala Asp Glu Leu Ile Ala Arg His 1450 1455 1460 cgc gaa ctc acc gga tcc gag acc aag ctg cgt gca caa gat ttg gtg 4531 Arg Glu Leu Thr Gly Ser Glu Thr Lys Leu Arg Ala Gln Asp Leu Val 1465 1470 1475 aaa atc atg ccg cgc gat ttc caa aaa gta ctc aac atc atc gaa acg 4579 Lys Ile Met Pro Arg Asp Phe Gln Lys Val Leu Asn Ile Ile Glu Thr 1480 1485 1490 gcc cac gct gag ggc caa gac cca gca atc aag atc atg gag gca gtg 4627 Ala His Ala Glu Gly Gln Asp Pro Ala Ile Lys Ile Met Glu Ala Val 1495 1500 1505 agc taatggccga cccacaagga ttc 4653 Ser 1510 <210> 72 <211> 1510 <212> PRT <213> Corynebacterium glutamicum <400> 72 Met Lys Pro Gln Gly Leu Tyr Asn Pro Ala His Glu His Asp Ala Cys 1 5 10 15 Gly Val Ala Phe Ile Ala Asp Ile His Gly Arg Pro Ser Arg Ser Ile 20 25 30 Val Asp Arg Ala Leu Glu Ala Leu Arg Asn Ile Asp His Arg Gly Ala 35 40 45 Ala Gly Ala Glu Lys Asn Thr Gly Asp Gly Ala Gly Ile Leu Met Gln 50 55 60 Ile Pro Asp Gly Phe Tyr Arg Glu Val Ser Gly Ile Glu Leu Pro Glu 65 70 75 80 Ala Gly Glu Tyr Ala Thr Gly Ile Ala Phe Leu Pro Arg Gly Arg Met 85 90 95 Ala Met Met Asp Ala Gln Lys Glu Ile Glu Arg Ile Ala Lys Gln Glu 100 105 110 Gly Ala Asp Val Leu Gly Trp Arg Met Val Pro Phe Asp Ser Arg Asp 115 120 125 Leu Gly Ser Met Ala Glu Glu Ala Met Pro Ser Phe Ala Gln Ile Phe 130 135 140 Leu Thr Val Pro Gly Lys Ser Gly Glu Asp Leu Asp Arg Val Met Phe 145 150 155 160 Phe Ile Arg Lys Arg Cys Glu Arg Glu Leu Gly Thr Thr Asn Gly Arg 165 170 175 Asp Thr Val Tyr Phe Pro Ser Leu Ser Ser Arg Thr Ile Ile Tyr Lys 180 185 190 Gly Met Leu Thr Thr Leu Gln Leu Glu Gly Phe Phe Glu Asp Leu Gly 195 200 205 Asp Ala Arg Leu Glu Ser Ala Ile Ala Ile Val His Ser Arg Phe Ser 210 215 220 Thr Asn Thr Phe Pro Ser Trp Pro Leu Ala His Pro Tyr Arg Phe Val 225 230 235 240 Ala His Asn Gly Glu Ile Asn Thr Val Arg Gly Asn Glu Asn Trp Met 245 250 255 Arg Ala Arg Glu Ala Leu Ile Lys Asn Asp Lys Leu Gly Asn Leu Ser 260 265 270 Ser Val Leu Pro Ile Cys Thr Pro Glu Gly Ser Asp Thr Ala Arg Phe 275 280 285 Asp Glu Ala Leu Glu Leu Leu His Leu Gly Gly Tyr Ser Leu Pro His 290 295 300 Ala Val Ala Met Met Ile Pro Gln Ala Trp Glu His Asn Lys Thr Leu 305 310 315 320 Ser Pro Glu Leu Arg Asp Phe Tyr Glu Tyr His Ser Cys Leu Met Glu 325 330 335 Pro Trp Asp Gly Pro Ala Ala Leu Ala Phe Thr Asp Gly Arg Phe Val 340 345 350 Gly Ala Val Leu Asp Arg Asn Gly Leu Arg Pro Gly Arg Ile Thr Ile 355 360 365 Thr Asp Ser Gly Leu Val Val Met Ala Ser Glu Ser Gly Val Leu Asp 370 375 380 Leu Arg Glu Glu Ser Val Val Lys Arg Thr Arg Val Gln Pro Gly Arg 385 390 395 400 Met Phe Leu Val Asp Thr Ala Glu Gly Arg Ile Val Glu Asp Glu Glu 405 410 415 Ile Lys Gln Lys Leu Ser Glu Ala Gln Pro Tyr Gly Glu Trp Ile Arg 420 425 430 Asp Asn Phe Val His Leu Asp Arg Leu Pro Gln Thr Arg Tyr Asn Tyr 435 440 445 Met Ala His Ser Arg Ala Val Leu Arg Gln Arg Val Phe Gly Ile Thr 450 455 460 Glu Glu Asp Val Asp Leu Leu Leu Leu Pro Met Ala Arg Gln Gly Ala 465 470 475 480 Glu Ala Ile Gly Ser Met Gly Ser Asp Thr Pro Ile Ala Ala Leu Ser 485 490 495 Gln Arg Pro Arg Met Leu Tyr Asp Phe Phe Ala Gln Arg Phe Ala Gln 500 505 510 Val Thr Asn Pro Pro Leu Asp Ser Ile Arg Glu Lys Pro Val Thr Ser 515 520 525 Met Phe Thr Leu Leu Gly Ala Gln Ser Asp Val Leu Asn Pro Gly Pro 530 535 540 Asp Ala Ala Arg Arg Ile Arg Leu Glu Ser Pro Ile Ile Asp Asn His 545 550 555 560 Glu Leu Ala Thr Leu Ile Asn Ala Asn Ala His Gly Glu Trp Asp Ser 565 570 575 Phe Gly Ala Ala Val Ile Ser Gly Leu Tyr Pro Val Ala His His Gly 580 585 590 Ala Gly Met Lys Ala Ala Ile Ala Arg Val Arg Arg Glu Val Ser Glu 595 600 605 Ala Ile Arg Asn Gly Lys Thr Leu Ile Val Leu Ser Asp Arg Glu Ser 610 615 620 Asp Glu Arg Met Ala Pro Ile Pro Ala Leu Leu Leu Thr Ser Ala Val 625 630 635 640 His Gln Tyr Leu Val Gln Gln Arg Thr Arg Thr Gln Cys Ser Leu Val 645 650 655 Val Glu Ser Gly Asp Ala Arg Glu Val His His Leu Ala Met Leu Ile 660 665 670 Gly Phe Gly Ala Asp Ala Ile Asn Pro Tyr Met Ala Phe Glu Thr Ile 675 680 685 Asp Glu Leu Arg Met Lys Gly Gln Leu Gly Asp Leu Ser Leu Asp Glu 690 695 700 Ala Ser Arg Asn Tyr Ile Lys Ala Ala Thr Thr Gly Val Leu Lys Val 705 710 715 720 Met Ser Lys Met Gly Ile Ala Thr Val Ser Ser Tyr Arg Gly Ala Gln 725 730 735 Leu Ala Asp Val Thr Gly Leu His Gln Asp Leu Leu Asp Asn Tyr Phe 740 745 750 Gly Gly Ile Ala Ser Pro Ile Ser Gly Ile Gly Leu Asp Glu Val Ala 755 760 765 Ala Asp Val Glu Ala Arg His Arg Ser Ala Phe Leu Pro Arg Pro Glu 770 775 780 Glu His Ala His Arg Glu Leu Asp Leu Gly Gly Glu Tyr Lys Trp Arg 785 790 795 800 Arg Glu Gly Glu Tyr His Leu Phe Asn Pro Glu Thr Ile Phe Lys Leu 805 810 815 Gln His Ala Thr Arg Ser Gly Ser Tyr Glu Ile Phe Lys Asp Tyr Thr 820 825 830 Arg Lys Val Asp Asp Gln Ser Thr Arg Leu Gly Thr Ile Arg Gly Leu 835 840 845 Phe Glu Phe Ser Thr Asp Arg Lys Pro Ile Ser Val Ser Glu Val Glu 850 855 860 Pro Val Ser Glu Ile Val Lys Arg Phe Ser Thr Gly Ala Met Ser Tyr 865 870 875 880 Gly Ser Ile Ser Ala Glu Ala His Glu Val Leu Ala Ile Ala Met Asn 885 890 895 Arg Leu Gly Gly Met Ser Asn Ser Gly Glu Gly Gly Glu Asp Ala Arg 900 905 910 Arg Phe Asp Val Glu Pro Asn Gly Asp Trp Lys Arg Ser Ala Ile Lys 915 920 925 Gln Val Ala Ser Gly Arg Phe Gly Val Thr Ser His Tyr Leu Asn Asn 930 935 940 Cys Thr Asp Ile Gln Ile Lys Met Ala Gln Gly Ala Lys Pro Gly Glu 945 950 955 960 Gly Gly Gln Leu Pro Pro Asn Lys Val Tyr Pro Trp Val Ala Glu Val 965 970 975 Arg Ile Thr Thr Pro Gly Val Gly Leu Ile Ser Pro Pro Pro His His 980 985 990 Asp Ile Tyr Ser Ile Glu Asp Leu Ala Gln Leu Ile His Asp Leu Lys 995 1000 1005 Asn Ala Asn Pro Arg Ala Arg Ile His Val Lys Leu Val Ala Glu Gln 1010 1015 1020 Gly Val Gly Thr Val Ala Ala Gly Val Ser Lys Ala His Ala Asp Val 1025 1030 1035 1040 Val Leu Ile Ser Gly His Asp Gly Gly Thr Gly Ala Ser Pro Leu Thr 1045 1050 1055 Ser Leu Lys His Ala Gly Gly Pro Trp Glu Leu Gly Leu Ala Glu Thr 1060 1065 1070 Gln Gln Thr Leu Leu Leu Asn Gly Leu Arg Asp Arg Ile Arg Val Gln 1075 1080 1085 Cys Asp Gly Gln Leu Lys Thr Gly Arg Asp Val Val Ile Ala Ala Leu 1090 1095 1100 Leu Gly Ala Glu Glu Phe Gly Phe Ala Thr Ala Pro Leu Val Val Glu 1105 1110 1115 1120 Gly Cys Ile Met Met Arg Val Cys His Leu Asp Thr Cys Pro Val Gly 1125 1130 1135 Ile Ala Thr Gln Asn Pro Asp Leu Arg Ser Lys Phe Thr Gly Lys Ala 1140 1145 1150 Glu His Val Val Asn Phe Phe Thr Phe Ile Ala Gln Glu Val Arg Glu 1155 1160 1165 Tyr Leu Ala Gln Leu Gly Phe Arg Ser Ile Asp Glu Ala Val Gly Gln 1170 1175 1180 Ala Gln Val Leu Arg Lys Arg Ser Gly Ile Pro Ala Asp Ser Arg Ala 1185 1190 1195 1200 Ala His Leu Asp Leu Ser Pro Ile Phe His Arg Pro Glu Thr Pro His 1205 1210 1215 Phe Pro Thr Gln Asp Val Arg Cys Thr Lys Thr Gln Glu His Ser Leu 1220 1225 1230 Glu Lys Ala Leu Asp Asn Ala Phe Ile Asp Lys Ala Ser Asp Thr Ile 1235 1240 1245 Thr Arg Ala Ala Ala Gly Val Glu Thr Ser Ile Val Ile Asp Ser Ser 1250 1255 1260 Ile Ser Asn Val Asn Arg Ser Val Gly Thr Met Leu Gly Ser Ala Val 1265 1270 1275 1280 Ser Arg Val Ala Gly Ala Gln Gly Leu Pro Asp Gly Thr Ile Thr Leu 1285 1290 1295 Asn Leu Gln Gly Cys Ala Gly Asn Ser Phe Gly Ala Phe Ile Pro Arg 1300 1305 1310 Gly Ile Thr Ile Asn Leu Thr Gly Asp Ala Asn Asp Phe Val Gly Lys 1315 1320 1325 Gly Leu Ser Gly Gly Lys Ile Val Ile Lys Pro Ser Ala Gln Ala Pro 1330 1335 1340 Lys Gln Leu Lys Asn Asn Pro Asn Ile Ile Ala Gly Asn Val Leu Gly 1345 1350 1355 1360 Tyr Gly Ala Thr Ser Gly Glu Leu Phe Ile Arg Gly Gln Val Gly Glu 1365 1370 1375 Arg Phe Cys Val Arg Asn Ser Gly Ala Thr Ala Val Val Glu Gly Ile 1380 1385 1390 Gly Asn His Gly Cys Glu Tyr Met Thr Gly Gly Arg Val Leu Val Leu 1395 1400 1405 Gly Pro Val Gly Glu Asn Phe Gly Ala Gly Met Ser Gly Gly Ile Ala 1410 1415 1420 Tyr Leu Ala Asn Ser Pro Asp Leu Asn Gln Lys Ile Asn Gly Glu Leu 1425 1430 1435 1440 Val Asp Val Val Pro Leu Ser Ala Asp Asp Leu Thr Trp Ala Asp Glu 1445 1450 1455 Leu Ile Ala Arg His Arg Glu Leu Thr Gly Ser Glu Thr Lys Leu Arg 1460 1465 1470 Ala Gln Asp Leu Val Lys Ile Met Pro Arg Asp Phe Gln Lys Val Leu 1475 1480 1485 Asn Ile Ile Glu Thr Ala His Ala Glu Gly Gln Asp Pro Ala Ile Lys 1490 1495 1500 Ile Met Glu Ala Val Ser 1505 1510 <210> 73 <211> 1906 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1906) <223> FRXA00007 <400> 73 atcgaaagta acccttttgt tacttgcgtt gcaggtagtg tccctgattt tcttattatc 60 gaacgattga tagaaacagg attaaagtga ggtatcccgc atg aaa cca caa gga 115 Met Lys Pro Gln Gly 1 5 ctc tac aac cct gcg cat gaa cat gac gcc tgc ggt gtg gcg ttt att 163 Leu Tyr Asn Pro Ala His Glu His Asp Ala Cys Gly Val Ala Phe Ile 10 15 20 gcg gat atc cac ggt cga ccc agc cgc agc att gtt gat cgt gca ctt 211 Ala Asp Ile His Gly Arg Pro Ser Arg Ser Ile Val Asp Arg Ala Leu 25 30 35 gag gcg ctt cgc aac att gac cac cga ggt gcc gcc ggt gca gag aag 259 Glu Ala Leu Arg Asn Ile Asp His Arg Gly Ala Ala Gly Ala Glu Lys 40 45 50 aac act ggc gat ggt gcg ggc atc ctc atg cag att ccg gac ggc ttt 307 Asn Thr Gly Asp Gly Ala Gly Ile Leu Met Gln Ile Pro Asp Gly Phe 55 60 65 tat cgt gaa gta tct ggc att gag ctt cct gag gca ggg gag tat gcc 355 Tyr Arg Glu Val Ser Gly Ile Glu Leu Pro Glu Ala Gly Glu Tyr Ala 70 75 80 85 act ggt att gcg ttc ttg cct cgc ggt cgc atg gcg atg atg gat gct 403 Thr Gly Ile Ala Phe Leu Pro Arg Gly Arg Met Ala Met Met Asp Ala 90 95 100 cag aag gaa att gag cgc atc gca aag caa gaa ggt gcc gat gtg ctt 451 Gln Lys Glu Ile Glu Arg Ile Ala Lys Gln Glu Gly Ala Asp Val Leu 105 110 115 ggt tgg cgc atg gtt cct ttt gat tct cgt gat ttg ggt tcc atg gct 499 Gly Trp Arg Met Val Pro Phe Asp Ser Arg Asp Leu Gly Ser Met Ala 120 125 130 gag gag gcg atg cct agt ttc gcg cag att ttc ctt act gtg cct gga 547 Glu Glu Ala Met Pro Ser Phe Ala Gln Ile Phe Leu Thr Val Pro Gly 135 140 145 aaa tct ggt gaa gat ctt gac cgt gtg atg ttc ttt atc cgt aag cgt 595 Lys Ser Gly Glu Asp Leu Asp Arg Val Met Phe Phe Ile Arg Lys Arg 150 155 160 165 tgt gag cgt gag ctg ggc acc acc aat ggt cgc gat acg gtg tat ttc 643 Cys Glu Arg Glu Leu Gly Thr Thr Asn Gly Arg Asp Thr Val Tyr Phe 170 175 180 ccg tcg cta tct tca cgc acc atc att tac aaa ggc atg ttg acc act 691 Pro Ser Leu Ser Ser Arg Thr Ile Ile Tyr Lys Gly Met Leu Thr Thr 185 190 195 ctg cag ctt gag ggc ttc ttt gag gat ctg ggt gat gct cgc ctg gag 739 Leu Gln Leu Glu Gly Phe Phe Glu Asp Leu Gly Asp Ala Arg Leu Glu 200 205 210 tcg gcc att gct att gtg cac tcg cgt ttc tcc acg aac act ttc cca 787 Ser Ala Ile Ala Ile Val His Ser Arg Phe Ser Thr Asn Thr Phe Pro 215 220 225 agc tgg ccg ctg gcg cac ccg tac cgt ttc gtt gcc cac aac ggt gag 835 Ser Trp Pro Leu Ala His Pro Tyr Arg Phe Val Ala His Asn Gly Glu 230 235 240 245 atc aac act gtg cgt ggc aat gaa aac tgg atg cgc gcc cgc gag gcg 883 Ile Asn Thr Val Arg Gly Asn Glu Asn Trp Met Arg Ala Arg Glu Ala 250 255 260 ctt atc aaa aac gac aag ctg ggc aat ttg agc agc gtg ctg cct atc 931 Leu Ile Lys Asn Asp Lys Leu Gly Asn Leu Ser Ser Val Leu Pro Ile 265 270 275 tgc acc ccg gag ggc tcg gat acc gcg cgt ttc gac gag gct ttg gag 979 Cys Thr Pro Glu Gly Ser Asp Thr Ala Arg Phe Asp Glu Ala Leu Glu 280 285 290 ctt ttg cac ctg ggc gga tac tca ctt ccg cat gct gtt gcg atg atg 1027 Leu Leu His Leu Gly Gly Tyr Ser Leu Pro His Ala Val Ala Met Met 295 300 305 atc cct cag gcg tgg gaa cac aac aag acg ctg agc cct gag ctg cgt 1075 Ile Pro Gln Ala Trp Glu His Asn Lys Thr Leu Ser Pro Glu Leu Arg 310 315 320 325 gat ttc tac gaa tac cac tct tgt ctg atg gag cca tgg gat ggt cct 1123 Asp Phe Tyr Glu Tyr His Ser Cys Leu Met Glu Pro Trp Asp Gly Pro 330 335 340 gca gcg ctg gca ttt act gac ggt cgt ttt gtg ggt gcc gtg ctg gac 1171 Ala Ala Leu Ala Phe Thr Asp Gly Arg Phe Val Gly Ala Val Leu Asp 345 350 355 cgt aat ggc ctg cga cct ggg cga atc acc att act gat tcg ggt ttg 1219 Arg Asn Gly Leu Arg Pro Gly Arg Ile Thr Ile Thr Asp Ser Gly Leu 360 365 370 gtt gtg atg gct tct gaa tcg gga gtg ttg gac ttg agg gag gag agc 1267 Val Val Met Ala Ser Glu Ser Gly Val Leu Asp Leu Arg Glu Glu Ser 375 380 385 gtc gta aag cgt act cgc gta cag cct gga cgc atg ttc ctt gtt gac 1315 Val Val Lys Arg Thr Arg Val Gln Pro Gly Arg Met Phe Leu Val Asp 390 395 400 405 act gcc gag ggc cgc atc gtt gaa gac gag gaa atc aag cag aaa tta 1363 Thr Ala Glu Gly Arg Ile Val Glu Asp Glu Glu Ile Lys Gln Lys Leu 410 415 420 agc gaa gcg cag cca tat ggt gag tgg att cgc gat aat ttt gtg cat 1411 Ser Glu Ala Gln Pro Tyr Gly Glu Trp Ile Arg Asp Asn Phe Val His 425 430 435 ctg gat cgt ctg cct cag aca cgc tac aac tac atg gcg cac tct cgt 1459 Leu Asp Arg Leu Pro Gln Thr Arg Tyr Asn Tyr Met Ala His Ser Arg 440 445 450 gct gtg ttg cgt cag cgt gtt ttc gga atc act gaa gaa gat gtg gat 1507 Ala Val Leu Arg Gln Arg Val Phe Gly Ile Thr Glu Glu Asp Val Asp 455 460 465 ttg ttg ctg ctg ccg atg gcc cgc cag ggt gct gag gcg att ggt tcc 1555 Leu Leu Leu Leu Pro Met Ala Arg Gln Gly Ala Glu Ala Ile Gly Ser 470 475 480 485 atg ggt tcg gat acg cca att gcg gcg cta tcc cag cga cca cgc atg 1603 Met Gly Ser Asp Thr Pro Ile Ala Ala Leu Ser Gln Arg Pro Arg Met 490 495 500 ctt tat gat ttc ttc gcg cag cgc ttt gct cag gtg aca aac cca ccg 1651 Leu Tyr Asp Phe Phe Ala Gln Arg Phe Ala Gln Val Thr Asn Pro Pro 505 510 515 ttg gac tct atc cgc gaa aag cct gtg acc agc atg ttc act ttg ttg 1699 Leu Asp Ser Ile Arg Glu Lys Pro Val Thr Ser Met Phe Thr Leu Leu 520 525 530 ggt gcg cag tct gac gtg ctc aat ccg ggt cct gat gcg gcg cga cgt 1747 Gly Ala Gln Ser Asp Val Leu Asn Pro Gly Pro Asp Ala Ala Arg Arg 535 540 545 att cgt ttg gaa tcg ccg atc att gat aac cat gag ctg gcc acc ttg 1795 Ile Arg Leu Glu Ser Pro Ile Ile Asp Asn His Glu Leu Ala Thr Leu 550 555 560 565 atc aat gcc aac gcg cat ggt gag tgg gat tcc ttt ggt gct gct gta 1843 Ile Asn Ala Asn Ala His Gly Glu Trp Asp Ser Phe Gly Ala Ala Val 570 575 580 att tct ggt ttg tac cca gtg gct cac cat ggt gcc ggc atg aag gct 1891 Ile Ser Gly Leu Tyr Pro Val Ala His His Gly Ala Gly Met Lys Ala 585 590 595 gcg att gct cgt gtg 1906 Ala Ile Ala Arg Val 600 <210> 74 <211> 602 <212> PRT <213> Corynebacterium glutamicum <400> 74 Met Lys Pro Gln Gly Leu Tyr Asn Pro Ala His Glu His Asp Ala Cys 1 5 10 15 Gly Val Ala Phe Ile Ala Asp Ile His Gly Arg Pro Ser Arg Ser Ile 20 25 30 Val Asp Arg Ala Leu Glu Ala Leu Arg Asn Ile Asp His Arg Gly Ala 35 40 45 Ala Gly Ala Glu Lys Asn Thr Gly Asp Gly Ala Gly Ile Leu Met Gln 50 55 60 Ile Pro Asp Gly Phe Tyr Arg Glu Val Ser Gly Ile Glu Leu Pro Glu 65 70 75 80 Ala Gly Glu Tyr Ala Thr Gly Ile Ala Phe Leu Pro Arg Gly Arg Met 85 90 95 Ala Met Met Asp Ala Gln Lys Glu Ile Glu Arg Ile Ala Lys Gln Glu 100 105 110 Gly Ala Asp Val Leu Gly Trp Arg Met Val Pro Phe Asp Ser Arg Asp 115 120 125 Leu Gly Ser Met Ala Glu Glu Ala Met Pro Ser Phe Ala Gln Ile Phe 130 135 140 Leu Thr Val Pro Gly Lys Ser Gly Glu Asp Leu Asp Arg Val Met Phe 145 150 155 160 Phe Ile Arg Lys Arg Cys Glu Arg Glu Leu Gly Thr Thr Asn Gly Arg 165 170 175 Asp Thr Val Tyr Phe Pro Ser Leu Ser Ser Arg Thr Ile Ile Tyr Lys 180 185 190 Gly Met Leu Thr Thr Leu Gln Leu Glu Gly Phe Phe Glu Asp Leu Gly 195 200 205 Asp Ala Arg Leu Glu Ser Ala Ile Ala Ile Val His Ser Arg Phe Ser 210 215 220 Thr Asn Thr Phe Pro Ser Trp Pro Leu Ala His Pro Tyr Arg Phe Val 225 230 235 240 Ala His Asn Gly Glu Ile Asn Thr Val Arg Gly Asn Glu Asn Trp Met 245 250 255 Arg Ala Arg Glu Ala Leu Ile Lys Asn Asp Lys Leu Gly Asn Leu Ser 260 265 270 Ser Val Leu Pro Ile Cys Thr Pro Glu Gly Ser Asp Thr Ala Arg Phe 275 280 285 Asp Glu Ala Leu Glu Leu Leu His Leu Gly Gly Tyr Ser Leu Pro His 290 295 300 Ala Val Ala Met Met Ile Pro Gln Ala Trp Glu His Asn Lys Thr Leu 305 310 315 320 Ser Pro Glu Leu Arg Asp Phe Tyr Glu Tyr His Ser Cys Leu Met Glu 325 330 335 Pro Trp Asp Gly Pro Ala Ala Leu Ala Phe Thr Asp Gly Arg Phe Val 340 345 350 Gly Ala Val Leu Asp Arg Asn Gly Leu Arg Pro Gly Arg Ile Thr Ile 355 360 365 Thr Asp Ser Gly Leu Val Val Met Ala Ser Glu Ser Gly Val Leu Asp 370 375 380 Leu Arg Glu Glu Ser Val Val Lys Arg Thr Arg Val Gln Pro Gly Arg 385 390 395 400 Met Phe Leu Val Asp Thr Ala Glu Gly Arg Ile Val Glu Asp Glu Glu 405 410 415 Ile Lys Gln Lys Leu Ser Glu Ala Gln Pro Tyr Gly Glu Trp Ile Arg 420 425 430 Asp Asn Phe Val His Leu Asp Arg Leu Pro Gln Thr Arg Tyr Asn Tyr 435 440 445 Met Ala His Ser Arg Ala Val Leu Arg Gln Arg Val Phe Gly Ile Thr 450 455 460 Glu Glu Asp Val Asp Leu Leu Leu Leu Pro Met Ala Arg Gln Gly Ala 465 470 475 480 Glu Ala Ile Gly Ser Met Gly Ser Asp Thr Pro Ile Ala Ala Leu Ser 485 490 495 Gln Arg Pro Arg Met Leu Tyr Asp Phe Phe Ala Gln Arg Phe Ala Gln 500 505 510 Val Thr Asn Pro Pro Leu Asp Ser Ile Arg Glu Lys Pro Val Thr Ser 515 520 525 Met Phe Thr Leu Leu Gly Ala Gln Ser Asp Val Leu Asn Pro Gly Pro 530 535 540 Asp Ala Ala Arg Arg Ile Arg Leu Glu Ser Pro Ile Ile Asp Asn His 545 550 555 560 Glu Leu Ala Thr Leu Ile Asn Ala Asn Ala His Gly Glu Trp Asp Ser 565 570 575 Phe Gly Ala Ala Val Ile Ser Gly Leu Tyr Pro Val Ala His His Gly 580 585 590 Ala Gly Met Lys Ala Ala Ile Ala Arg Val 595 600 <210> 75 <211> 1362 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (70)..(1362) <223> FRXA00364 <400> 75 accaatttct ggcatcggtc tggatgaagt tgcagctgac gtagaaagct cgtcaccgca 60 gcgcatttt ttg cca cgc cct gaa gag cac gct cac cgt gaa ttg gat ttg 111 Leu Pro Arg Pro Glu Glu His Ala His Arg Glu Leu Asp Leu 1 5 10 ggt ggt gaa tac aag tgg cgc cgc gaa ggt gaa tac cac ctg ttc aac 159 Gly Gly Glu Tyr Lys Trp Arg Arg Glu Gly Glu Tyr His Leu Phe Asn 15 20 25 30 cca gaa acc atc ttc aag ctg cag cat gca acg cgt tct ggc agc tac 207 Pro Glu Thr Ile Phe Lys Leu Gln His Ala Thr Arg Ser Gly Ser Tyr 35 40 45 gag att ttc aag gat tac acc cgc aag gtt gat gat caa tcc act cgc 255 Glu Ile Phe Lys Asp Tyr Thr Arg Lys Val Asp Asp Gln Ser Thr Arg 50 55 60 ttg ggt act att cgt gga ctg ttt gag ttc agc acg gac cgc aag cca 303 Leu Gly Thr Ile Arg Gly Leu Phe Glu Phe Ser Thr Asp Arg Lys Pro 65 70 75 att tcg gtg tct gag gtg gag ccg gtc agt gag atc gtg aag cgt ttc 351 Ile Ser Val Ser Glu Val Glu Pro Val Ser Glu Ile Val Lys Arg Phe 80 85 90 tcc act ggt gcg atg tct tat ggc tcg att tct gct gaa gcc cat gag 399 Ser Thr Gly Ala Met Ser Tyr Gly Ser Ile Ser Ala Glu Ala His Glu 95 100 105 110 gtc ttg gcc atc gcc atg aac cga ctg ggc ggt atg tcc aac tcc ggc 447 Val Leu Ala Ile Ala Met Asn Arg Leu Gly Gly Met Ser Asn Ser Gly 115 120 125 gaa ggt ggc gag gac gcc cgc cga ttt gat gtg gaa ccc aac ggt gac 495 Glu Gly Gly Glu Asp Ala Arg Arg Phe Asp Val Glu Pro Asn Gly Asp 130 135 140 tgg aag cgc tct gcc att aag cag gtg gcc tcg gga cgt ttc ggc gtg 543 Trp Lys Arg Ser Ala Ile Lys Gln Val Ala Ser Gly Arg Phe Gly Val 145 150 155 acc agc cac tac ttg aac aac tgc acc gat att cag atc aag atg gca 591 Thr Ser His Tyr Leu Asn Asn Cys Thr Asp Ile Gln Ile Lys Met Ala 160 165 170 cag ggc gca aag ccc ggt gaa ggt ggc cag ctg cca cca aac aag gtg 639 Gln Gly Ala Lys Pro Gly Glu Gly Gly Gln Leu Pro Pro Asn Lys Val 175 180 185 190 tac cca tgg gtt gca gaa gtc cgc atc acc acc cca ggc gtt ggt ctg 687 Tyr Pro Trp Val Ala Glu Val Arg Ile Thr Thr Pro Gly Val Gly Leu 195 200 205 att tcc cct cca cca cac cac gat att tac tcc att gag gat ctg gct 735 Ile Ser Pro Pro Pro His His Asp Ile Tyr Ser Ile Glu Asp Leu Ala 210 215 220 cag ctg atc cac gac ctg aag aac gct aac cca cgc gca cga atc cac 783 Gln Leu Ile His Asp Leu Lys Asn Ala Asn Pro Arg Ala Arg Ile His 225 230 235 gtg aag cta gtg gca gaa caa ggc gtg ggc acc gtt gcc gca ggt gtg 831 Val Lys Leu Val Ala Glu Gln Gly Val Gly Thr Val Ala Ala Gly Val 240 245 250 tcc aaa gca cac gct gat gtg gtg ctt att tcc ggc cac gat ggc gga 879 Ser Lys Ala His Ala Asp Val Val Leu Ile Ser Gly His Asp Gly Gly 255 260 265 270 act ggc gca tct cct ttg acc tcc ctg aag cat gcc ggt ggt cca tgg 927 Thr Gly Ala Ser Pro Leu Thr Ser Leu Lys His Ala Gly Gly Pro Trp 275 280 285 gag ttg ggc ttg gct gaa acc cag caa acg ttg ctg ctc aac ggc ctg 975 Glu Leu Gly Leu Ala Glu Thr Gln Gln Thr Leu Leu Leu Asn Gly Leu 290 295 300 cgc gat cgt att cgc gtg cag tgc gat ggt cag ctg aaa act ggc cga 1023 Arg Asp Arg Ile Arg Val Gln Cys Asp Gly Gln Leu Lys Thr Gly Arg 305 310 315 gac gtg gtt atc gca gct ctt ctc ggt gcc gaa gaa ttc ggt ttt gcc 1071 Asp Val Val Ile Ala Ala Leu Leu Gly Ala Glu Glu Phe Gly Phe Ala 320 325 330 acc gca ccg ctg gtg gtt gaa ggc tgc atc atg atg cgc gtc tgc cac 1119 Thr Ala Pro Leu Val Val Glu Gly Cys Ile Met Met Arg Val Cys His 335 340 345 350 ctg gac acc tgc ccg gtg ggt atc gct acc cag aac ccg gat ttg cgt 1167 Leu Asp Thr Cys Pro Val Gly Ile Ala Thr Gln Asn Pro Asp Leu Arg 355 360 365 tcc aag ttc acc ggc aag gct gaa cac gtg gtc aac ttc ttc acc ttc 1215 Ser Lys Phe Thr Gly Lys Ala Glu His Val Val Asn Phe Phe Thr Phe 370 375 380 atc gcc cag gaa gtc cgt gag tac ttg gca cag ctt ggt ttc cgc tct 1263 Ile Ala Gln Glu Val Arg Glu Tyr Leu Ala Gln Leu Gly Phe Arg Ser 385 390 395 att gat gaa gcc gtc gga caa gcc cag gtg ctg cgc aag cgt tcc gga 1311 Ile Asp Glu Ala Val Gly Gln Ala Gln Val Leu Arg Lys Arg Ser Gly 400 405 410 atc cca gct gat tcc cgc gca gca cac ctg gat ttg agc cca att ttc 1359 Ile Pro Ala Asp Ser Arg Ala Ala His Leu Asp Leu Ser Pro Ile Phe 415 420 425 430 atc 1362 Ile <210> 76 <211> 431 <212> PRT <213> Corynebacterium glutamicum <400> 76 Leu Pro Arg Pro Glu Glu His Ala His Arg Glu Leu Asp Leu Gly Gly 1 5 10 15 Glu Tyr Lys Trp Arg Arg Glu Gly Glu Tyr His Leu Phe Asn Pro Glu 20 25 30 Thr Ile Phe Lys Leu Gln His Ala Thr Arg Ser Gly Ser Tyr Glu Ile 35 40 45 Phe Lys Asp Tyr Thr Arg Lys Val Asp Asp Gln Ser Thr Arg Leu Gly 50 55 60 Thr Ile Arg Gly Leu Phe Glu Phe Ser Thr Asp Arg Lys Pro Ile Ser 65 70 75 80 Val Ser Glu Val Glu Pro Val Ser Glu Ile Val Lys Arg Phe Ser Thr 85 90 95 Gly Ala Met Ser Tyr Gly Ser Ile Ser Ala Glu Ala His Glu Val Leu 100 105 110 Ala Ile Ala Met Asn Arg Leu Gly Gly Met Ser Asn Ser Gly Glu Gly 115 120 125 Gly Glu Asp Ala Arg Arg Phe Asp Val Glu Pro Asn Gly Asp Trp Lys 130 135 140 Arg Ser Ala Ile Lys Gln Val Ala Ser Gly Arg Phe Gly Val Thr Ser 145 150 155 160 His Tyr Leu Asn Asn Cys Thr Asp Ile Gln Ile Lys Met Ala Gln Gly 165 170 175 Ala Lys Pro Gly Glu Gly Gly Gln Leu Pro Pro Asn Lys Val Tyr Pro 180 185 190 Trp Val Ala Glu Val Arg Ile Thr Thr Pro Gly Val Gly Leu Ile Ser 195 200 205 Pro Pro Pro His His Asp Ile Tyr Ser Ile Glu Asp Leu Ala Gln Leu 210 215 220 Ile His Asp Leu Lys Asn Ala Asn Pro Arg Ala Arg Ile His Val Lys 225 230 235 240 Leu Val Ala Glu Gln Gly Val Gly Thr Val Ala Ala Gly Val Ser Lys 245 250 255 Ala His Ala Asp Val Val Leu Ile Ser Gly His Asp Gly Gly Thr Gly 260 265 270 Ala Ser Pro Leu Thr Ser Leu Lys His Ala Gly Gly Pro Trp Glu Leu 275 280 285 Gly Leu Ala Glu Thr Gln Gln Thr Leu Leu Leu Asn Gly Leu Arg Asp 290 295 300 Arg Ile Arg Val Gln Cys Asp Gly Gln Leu Lys Thr Gly Arg Asp Val 305 310 315 320 Val Ile Ala Ala Leu Leu Gly Ala Glu Glu Phe Gly Phe Ala Thr Ala 325 330 335 Pro Leu Val Val Glu Gly Cys Ile Met Met Arg Val Cys His Leu Asp 340 345 350 Thr Cys Pro Val Gly Ile Ala Thr Gln Asn Pro Asp Leu Arg Ser Lys 355 360 365 Phe Thr Gly Lys Ala Glu His Val Val Asn Phe Phe Thr Phe Ile Ala 370 375 380 Gln Glu Val Arg Glu Tyr Leu Ala Gln Leu Gly Phe Arg Ser Ile Asp 385 390 395 400 Glu Ala Val Gly Gln Ala Gln Val Leu Arg Lys Arg Ser Gly Ile Pro 405 410 415 Ala Asp Ser Arg Ala Ala His Leu Asp Leu Ser Pro Ile Phe Ile 420 425 430 <210> 77 <211> 866 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(843) <223> FRXA00367 <400> 77 cac agc cta gaa aaa gcc ctg gac aac gca ttt att gat aag gct tcg 48 His Ser Leu Glu Lys Ala Leu Asp Asn Ala Phe Ile Asp Lys Ala Ser 1 5 10 15 gac acg atc acc cgt gcc gca gcg ggt gtg gaa acc agc att gtt att 96 Asp Thr Ile Thr Arg Ala Ala Ala Gly Val Glu Thr Ser Ile Val Ile 20 25 30 gat agc tcc atc agc aac gtc aac cgt tca gtt ggc acg atg ctg ggt 144 Asp Ser Ser Ile Ser Asn Val Asn Arg Ser Val Gly Thr Met Leu Gly 35 40 45 tct gca gtc agc cgc gtg gct ggt gcc caa ggt ttg cca gac ggc acc 192 Ser Ala Val Ser Arg Val Ala Gly Ala Gln Gly Leu Pro Asp Gly Thr 50 55 60 atc acc ttg aat ctt caa ggc tgc gcc ggt aac tcc ttt ggc gcg ttc 240 Ile Thr Leu Asn Leu Gln Gly Cys Ala Gly Asn Ser Phe Gly Ala Phe 65 70 75 80 atc cca cga ggc atc acc atc aac ctc acc ggc gat gcc aat gac ttt 288 Ile Pro Arg Gly Ile Thr Ile Asn Leu Thr Gly Asp Ala Asn Asp Phe 85 90 95 gtg ggc aag gga tta tct ggc gga aag att gtg atc aag cct tcc gct 336 Val Gly Lys Gly Leu Ser Gly Gly Lys Ile Val Ile Lys Pro Ser Ala 100 105 110 cag gct ccg aag cag ctg aag aac aat cca aat atc att gcc gga aac 384 Gln Ala Pro Lys Gln Leu Lys Asn Asn Pro Asn Ile Ile Ala Gly Asn 115 120 125 gtg ctt gga tac ggc gca acc agt ggt gaa ttg ttc att cgt ggc cag 432 Val Leu Gly Tyr Gly Ala Thr Ser Gly Glu Leu Phe Ile Arg Gly Gln 130 135 140 gtc ggc gaa cgt ttc tgc gtc cgt aac tct ggc gcc acc gca gtg gtt 480 Val Gly Glu Arg Phe Cys Val Arg Asn Ser Gly Ala Thr Ala Val Val 145 150 155 160 gaa ggt atc gga aac cac ggt tgt gag tac atg act ggc ggc cga gtc 528 Glu Gly Ile Gly Asn His Gly Cys Glu Tyr Met Thr Gly Gly Arg Val 165 170 175 ctg gtt ttg ggc ccg gtt ggt gag aac ttt ggt gcc ggc atg tct ggt 576 Leu Val Leu Gly Pro Val Gly Glu Asn Phe Gly Ala Gly Met Ser Gly 180 185 190 ggc att gca tac ctg gct aat tcc ccg gac cta aac cag aag atc aat 624 Gly Ile Ala Tyr Leu Ala Asn Ser Pro Asp Leu Asn Gln Lys Ile Asn 195 200 205 ggc gaa ttg gtg gat gtt gtt cca ctg agc gct gac gat ctg acg tgg 672 Gly Glu Leu Val Asp Val Val Pro Leu Ser Ala Asp Asp Leu Thr Trp 210 215 220 gct gat gag ctc att gct cgc cac cgc gaa ctc acc gga tcc gag acc 720 Ala Asp Glu Leu Ile Ala Arg His Arg Glu Leu Thr Gly Ser Glu Thr 225 230 235 240 aag ctg cgt gca caa gat ttg gtg aaa atc atg ccg cgc gat ttc caa 768 Lys Leu Arg Ala Gln Asp Leu Val Lys Ile Met Pro Arg Asp Phe Gln 245 250 255 aaa gta ctc aac atc atc gaa acg gcc cac gct gag ggc caa gac cca 816 Lys Val Leu Asn Ile Ile Glu Thr Ala His Ala Glu Gly Gln Asp Pro 260 265 270 gca atc aag atc atg gag gca gtg agc taatggccga cccacaagga 863 Ala Ile Lys Ile Met Glu Ala Val Ser 275 280 ttc 866 <210> 78 <211> 281 <212> PRT <213> Corynebacterium glutamicum <400> 78 His Ser Leu Glu Lys Ala Leu Asp Asn Ala Phe Ile Asp Lys Ala Ser 1 5 10 15 Asp Thr Ile Thr Arg Ala Ala Ala Gly Val Glu Thr Ser Ile Val Ile 20 25 30 Asp Ser Ser Ile Ser Asn Val Asn Arg Ser Val Gly Thr Met Leu Gly 35 40 45 Ser Ala Val Ser Arg Val Ala Gly Ala Gln Gly Leu Pro Asp Gly Thr 50 55 60 Ile Thr Leu Asn Leu Gln Gly Cys Ala Gly Asn Ser Phe Gly Ala Phe 65 70 75 80 Ile Pro Arg Gly Ile Thr Ile Asn Leu Thr Gly Asp Ala Asn Asp Phe 85 90 95 Val Gly Lys Gly Leu Ser Gly Gly Lys Ile Val Ile Lys Pro Ser Ala 100 105 110 Gln Ala Pro Lys Gln Leu Lys Asn Asn Pro Asn Ile Ile Ala Gly Asn 115 120 125 Val Leu Gly Tyr Gly Ala Thr Ser Gly Glu Leu Phe Ile Arg Gly Gln 130 135 140 Val Gly Glu Arg Phe Cys Val Arg Asn Ser Gly Ala Thr Ala Val Val 145 150 155 160 Glu Gly Ile Gly Asn His Gly Cys Glu Tyr Met Thr Gly Gly Arg Val 165 170 175 Leu Val Leu Gly Pro Val Gly Glu Asn Phe Gly Ala Gly Met Ser Gly 180 185 190 Gly Ile Ala Tyr Leu Ala Asn Ser Pro Asp Leu Asn Gln Lys Ile Asn 195 200 205 Gly Glu Leu Val Asp Val Val Pro Leu Ser Ala Asp Asp Leu Thr Trp 210 215 220 Ala Asp Glu Leu Ile Ala Arg His Arg Glu Leu Thr Gly Ser Glu Thr 225 230 235 240 Lys Leu Arg Ala Gln Asp Leu Val Lys Ile Met Pro Arg Asp Phe Gln 245 250 255 Lys Val Leu Asn Ile Ile Glu Thr Ala His Ala Glu Gly Gln Asp Pro 260 265 270 Ala Ile Lys Ile Met Glu Ala Val Ser 275 280 <210> 79 <211> 1494 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1471) <223> RXN00076 <400> 79 tctaggagtg ttaaacagcc tggacttgaa acacctttaa ctacttgatt ttcacaccct 60 tgtttccata aaagggctca cgaaaggcaa cttcaaacac atg aca act ccc ctg 115 Met Thr Thr Pro Leu 1 5 cgc gta gcc gtc atc gga gct ggc cct gct ggc att tac gca tcc gac 163 Arg Val Ala Val Ile Gly Ala Gly Pro Ala Gly Ile Tyr Ala Ser Asp 10 15 20 ctc ctc atc cgc aat gaa gag cgc gaa gtg ttc gtt gac ctt ttc gag 211 Leu Leu Ile Arg Asn Glu Glu Arg Glu Val Phe Val Asp Leu Phe Glu 25 30 35 caa atg cct gca ccg ttc gga ctc atc cgt tac ggc gtt gct cca gac 259 Gln Met Pro Ala Pro Phe Gly Leu Ile Arg Tyr Gly Val Ala Pro Asp 40 45 50 cac cca cgc atc aag ggc atc gtt aag tcc ctg cac aac gtg ttg gac 307 His Pro Arg Ile Lys Gly Ile Val Lys Ser Leu His Asn Val Leu Asp 55 60 65 aag cca cgc ctg cgc ctg ctc ggt aac att gaa atc ggc aaa gac atc 355 Lys Pro Arg Leu Arg Leu Leu Gly Asn Ile Glu Ile Gly Lys Asp Ile 70 75 80 85 acc gtc gaa gaa ctc cgc gac tac tac gat gca gtc gtg ttc tcc acc 403 Thr Val Glu Glu Leu Arg Asp Tyr Tyr Asp Ala Val Val Phe Ser Thr 90 95 100 ggc gca gtt gca gac cgc gac ctc aac atc ccc gga att gaa gca gaa 451 Gly Ala Val Ala Asp Arg Asp Leu Asn Ile Pro Gly Ile Glu Ala Glu 105 110 115 ggc tcc ttc ggt gcc ggc gag ttc gtt ggc ttc tac gac ggc aac cca 499 Gly Ser Phe Gly Ala Gly Glu Phe Val Gly Phe Tyr Asp Gly Asn Pro 120 125 130 cgc ttc gag cgc tcc tgg gat ctg tct gca cag tcc gtc gct gtt atc 547 Arg Phe Glu Arg Ser Trp Asp Leu Ser Ala Gln Ser Val Ala Val Ile 135 140 145 ggc gtt ggt aac gtc ggc ctc gac gta gcc cgc atc ctg gct aag aca 595 Gly Val Gly Asn Val Gly Leu Asp Val Ala Arg Ile Leu Ala Lys Thr 150 155 160 165 ggc gac gag ctc aaa gtc acc gaa att tcc gac aac gtc tac gac tcc 643 Gly Asp Glu Leu Lys Val Thr Glu Ile Ser Asp Asn Val Tyr Asp Ser 170 175 180 ctc aaa gaa aac aag gcc act gaa gtg cac gtt ttc gga cgt cgt ggc 691 Leu Lys Glu Asn Lys Ala Thr Glu Val His Val Phe Gly Arg Arg Gly 185 190 195 cca gca cag gtc aag ttc acc cca cag gaa ctc aaa gaa ctc gac cac 739 Pro Ala Gln Val Lys Phe Thr Pro Gln Glu Leu Lys Glu Leu Asp His 200 205 210 tcc ccc acc atc aac gtg gtt gtt gat cca gaa gac atc gac tac gac 787 Ser Pro Thr Ile Asn Val Val Val Asp Pro Glu Asp Ile Asp Tyr Asp 215 220 225 ggc gcc tct gaa gaa gcc cgc cgc gca tcc aag tcc cag gac ctg gtc 835 Gly Ala Ser Glu Glu Ala Arg Arg Ala Ser Lys Ser Gln Asp Leu Val 230 235 240 245 tgc cag atc ctg gaa cag tac gca atc cgc gag cca aag gac gct ccg 883 Cys Gln Ile Leu Glu Gln Tyr Ala Ile Arg Glu Pro Lys Asp Ala Pro 250 255 260 cac acc ctg cag atc cac ctc ttt gaa aac cca gtt gag gtt ctt caa 931 His Thr Leu Gln Ile His Leu Phe Glu Asn Pro Val Glu Val Leu Gln 265 270 275 aag gac ggc aag gtt gtt ggc ctg cgc acc gaa cgc acc tca ctt gat 979 Lys Asp Gly Lys Val Val Gly Leu Arg Thr Glu Arg Thr Ser Leu Asp 280 285 290 ggc aac ggc ggc gta aac gga acc ggc gaa ttc aag gac tgg cca gtc 1027 Gly Asn Gly Gly Val Asn Gly Thr Gly Glu Phe Lys Asp Trp Pro Val 295 300 305 cag gct gtc tac cgc gca gtc ggc tac aag tcc gac ccc atc gac ggc 1075 Gln Ala Val Tyr Arg Ala Val Gly Tyr Lys Ser Asp Pro Ile Asp Gly 310 315 320 325 gtc cca ttc gat gag aac aag cac gtc atc cct aat gac ggc gga cat 1123 Val Pro Phe Asp Glu Asn Lys His Val Ile Pro Asn Asp Gly Gly His 330 335 340 gtc ctc acc gct cca ggc gca gaa cca gta cca ggc ctc tat gca acc 1171 Val Leu Thr Ala Pro Gly Ala Glu Pro Val Pro Gly Leu Tyr Ala Thr 345 350 355 ggc tgg atc aag cgt gga cca atc ggt cta atc ggc aac acc aag tcc 1219 Gly Trp Ile Lys Arg Gly Pro Ile Gly Leu Ile Gly Asn Thr Lys Ser 360 365 370 gac gcc aag gaa acc acc gac atc ctc atc aag gat gcc gtc gcc ggt 1267 Asp Ala Lys Glu Thr Thr Asp Ile Leu Ile Lys Asp Ala Val Ala Gly 375 380 385 gta ctt gaa gct cca aag cac cag ggc gaa gaa gcc atc atc gag ctt 1315 Val Leu Glu Ala Pro Lys His Gln Gly Glu Glu Ala Ile Ile Glu Leu 390 395 400 405 ctc gat tcc cgc aac atc cca ttc acc acc tgg gaa ggc tgg tac aaa 1363 Leu Asp Ser Arg Asn Ile Pro Phe Thr Thr Trp Glu Gly Trp Tyr Lys 410 415 420 ctc gac gca gca gag cgc gca ctc ggt gaa gcc gaa ggc cgc gag cgc 1411 Leu Asp Ala Ala Glu Arg Ala Leu Gly Glu Ala Glu Gly Arg Glu Arg 425 430 435 aag aag att gtt gat tgg gaa gaa atg gtc cgc cag gcc cgc gaa gct 1459 Lys Lys Ile Val Asp Trp Glu Glu Met Val Arg Gln Ala Arg Glu Ala 440 445 450 cca gca att gtc taaattgttt taacgcgtga agc 1494 Pro Ala Ile Val 455 <210> 80 <211> 457 <212> PRT <213> Corynebacterium glutamicum <400> 80 Met Thr Thr Pro Leu Arg Val Ala Val Ile Gly Ala Gly Pro Ala Gly 1 5 10 15 Ile Tyr Ala Ser Asp Leu Leu Ile Arg Asn Glu Glu Arg Glu Val Phe 20 25 30 Val Asp Leu Phe Glu Gln Met Pro Ala Pro Phe Gly Leu Ile Arg Tyr 35 40 45 Gly Val Ala Pro Asp His Pro Arg Ile Lys Gly Ile Val Lys Ser Leu 50 55 60 His Asn Val Leu Asp Lys Pro Arg Leu Arg Leu Leu Gly Asn Ile Glu 65 70 75 80 Ile Gly Lys Asp Ile Thr Val Glu Glu Leu Arg Asp Tyr Tyr Asp Ala 85 90 95 Val Val Phe Ser Thr Gly Ala Val Ala Asp Arg Asp Leu Asn Ile Pro 100 105 110 Gly Ile Glu Ala Glu Gly Ser Phe Gly Ala Gly Glu Phe Val Gly Phe 115 120 125 Tyr Asp Gly Asn Pro Arg Phe Glu Arg Ser Trp Asp Leu Ser Ala Gln 130 135 140 Ser Val Ala Val Ile Gly Val Gly Asn Val Gly Leu Asp Val Ala Arg 145 150 155 160 Ile Leu Ala Lys Thr Gly Asp Glu Leu Lys Val Thr Glu Ile Ser Asp 165 170 175 Asn Val Tyr Asp Ser Leu Lys Glu Asn Lys Ala Thr Glu Val His Val 180 185 190 Phe Gly Arg Arg Gly Pro Ala Gln Val Lys Phe Thr Pro Gln Glu Leu 195 200 205 Lys Glu Leu Asp His Ser Pro Thr Ile Asn Val Val Val Asp Pro Glu 210 215 220 Asp Ile Asp Tyr Asp Gly Ala Ser Glu Glu Ala Arg Arg Ala Ser Lys 225 230 235 240 Ser Gln Asp Leu Val Cys Gln Ile Leu Glu Gln Tyr Ala Ile Arg Glu 245 250 255 Pro Lys Asp Ala Pro His Thr Leu Gln Ile His Leu Phe Glu Asn Pro 260 265 270 Val Glu Val Leu Gln Lys Asp Gly Lys Val Val Gly Leu Arg Thr Glu 275 280 285 Arg Thr Ser Leu Asp Gly Asn Gly Gly Val Asn Gly Thr Gly Glu Phe 290 295 300 Lys Asp Trp Pro Val Gln Ala Val Tyr Arg Ala Val Gly Tyr Lys Ser 305 310 315 320 Asp Pro Ile Asp Gly Val Pro Phe Asp Glu Asn Lys His Val Ile Pro 325 330 335 Asn Asp Gly Gly His Val Leu Thr Ala Pro Gly Ala Glu Pro Val Pro 340 345 350 Gly Leu Tyr Ala Thr Gly Trp Ile Lys Arg Gly Pro Ile Gly Leu Ile 355 360 365 Gly Asn Thr Lys Ser Asp Ala Lys Glu Thr Thr Asp Ile Leu Ile Lys 370 375 380 Asp Ala Val Ala Gly Val Leu Glu Ala Pro Lys His Gln Gly Glu Glu 385 390 395 400 Ala Ile Ile Glu Leu Leu Asp Ser Arg Asn Ile Pro Phe Thr Thr Trp 405 410 415 Glu Gly Trp Tyr Lys Leu Asp Ala Ala Glu Arg Ala Leu Gly Glu Ala 420 425 430 Glu Gly Arg Glu Arg Lys Lys Ile Val Asp Trp Glu Glu Met Val Arg 435 440 445 Gln Ala Arg Glu Ala Pro Ala Ile Val 450 455 <210> 81 <211> 786 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(763) <223> FRXA00075 <220> <221> VARIANT <222> 187 <223> Xaa = Val or Ala <220> <221> VARIANT <222> 188 <223> Xaa = Thr or Ser <220> <221> VARIANT <222> 209 <223> Xaa = Lys or Gln <220> <221> VARIANT <222> 212 <223> Xaa = Arg <400> 81 tctaggagtg ttaaacagcc tggacttgaa acacctttaa ctacttgatt ttcacaccct 60 tgtttccata aaagggctca cgaaaggcaa cttcaaacac atg aca act ccc ctg 115 Met Thr Thr Pro Leu 1 5 cgc gta gcc gtc atc gga gct ggc cct gct ggc att tac gca tcc gac 163 Arg Val Ala Val Ile Gly Ala Gly Pro Ala Gly Ile Tyr Ala Ser Asp 10 15 20 ctc ctc atc cgc aat gaa gag cgc gaa gtg ttc gtt gac ctt ttc gag 211 Leu Leu Ile Arg Asn Glu Glu Arg Glu Val Phe Val Asp Leu Phe Glu 25 30 35 caa atg cct gca ccg ttc gga ctc atc cgt tac ggc gtt gct cca gac 259 Gln Met Pro Ala Pro Phe Gly Leu Ile Arg Tyr Gly Val Ala Pro Asp 40 45 50 cac cca cgc atc aag ggc atc gtt aag tcc ctg cac aac gtg ttg gac 307 His Pro Arg Ile Lys Gly Ile Val Lys Ser Leu His Asn Val Leu Asp 55 60 65 aag cca cgc ctg cgc ctg ctc ggt aac att gaa atc ggc aaa gac atc 355 Lys Pro Arg Leu Arg Leu Leu Gly Asn Ile Glu Ile Gly Lys Asp Ile 70 75 80 85 acc gtc gaa gaa ctc cgc gac tac tac gat gca gtc gtg ttc tcc acc 403 Thr Val Glu Glu Leu Arg Asp Tyr Tyr Asp Ala Val Val Phe Ser Thr 90 95 100 ggc gca gtt gca gac cgc gac ctc aac atc ccc gga att gaa gca gaa 451 Gly Ala Val Ala Asp Arg Asp Leu Asn Ile Pro Gly Ile Glu Ala Glu 105 110 115 ggc tcc ttc ggt gcc ggc gag ttc gtt ggc ttc tac gac ggc aac cca 499 Gly Ser Phe Gly Ala Gly Glu Phe Val Gly Phe Tyr Asp Gly Asn Pro 120 125 130 cgc ttc gag cgc tcc tgg gat ctg tct gca cag tcc gtc gct gtt atc 547 Arg Phe Glu Arg Ser Trp Asp Leu Ser Ala Gln Ser Val Ala Val Ile 135 140 145 ggc gtt ggt aac gtc ggc ctc gac gta gcc cgc atc ctg gct aag aca 595 Gly Val Gly Asn Val Gly Leu Asp Val Ala Arg Ile Leu Ala Lys Thr 150 155 160 165 ggc gac gag ctc aaa gtc acc gaa att tcc gac aac gtc tac gac tcc 643 Gly Asp Glu Leu Lys Val Thr Glu Ile Ser Asp Asn Val Tyr Asp Ser 170 175 180 ctc aaa gaa aac aag gyc wct gaa gtg cac gtt ttc gga cgt cgg tgg 691 Leu Lys Glu Asn Lys Xaa Xaa Glu Val His Val Phe Gly Arg Arg Trp 185 190 195 ccc agc aca ggt caa gtt cac ccc aca gga act maa aga act cgr cca 739 Pro Ser Thr Gly Gln Val His Pro Thr Gly Thr Xaa Arg Thr Xaa Pro 200 205 210 ctc ccc cac cat caa cgt ggt tgt tgatccagaa gacatcgact acg 786 Leu Pro His His Gln Arg Gly Cys 215 220 <210> 82 <211> 221 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 187 <223> Xaa = Val or Ala <220> <221> VARIANT <222> 188 <223> Xaa = Thr or Ser <220> <221> VARIANT <222> 209 <223> Xaa = Lys or Gln <220> <221> VARIANT <222> 212 <223> Xaa = Arg <400> 82 Met Thr Thr Pro Leu Arg Val Ala Val Ile Gly Ala Gly Pro Ala Gly 1 5 10 15 Ile Tyr Ala Ser Asp Leu Leu Ile Arg Asn Glu Glu Arg Glu Val Phe 20 25 30 Val Asp Leu Phe Glu Gln Met Pro Ala Pro Phe Gly Leu Ile Arg Tyr 35 40 45 Gly Val Ala Pro Asp His Pro Arg Ile Lys Gly Ile Val Lys Ser Leu 50 55 60 His Asn Val Leu Asp Lys Pro Arg Leu Arg Leu Leu Gly Asn Ile Glu 65 70 75 80 Ile Gly Lys Asp Ile Thr Val Glu Glu Leu Arg Asp Tyr Tyr Asp Ala 85 90 95 Val Val Phe Ser Thr Gly Ala Val Ala Asp Arg Asp Leu Asn Ile Pro 100 105 110 Gly Ile Glu Ala Glu Gly Ser Phe Gly Ala Gly Glu Phe Val Gly Phe 115 120 125 Tyr Asp Gly Asn Pro Arg Phe Glu Arg Ser Trp Asp Leu Ser Ala Gln 130 135 140 Ser Val Ala Val Ile Gly Val Gly Asn Val Gly Leu Asp Val Ala Arg 145 150 155 160 Ile Leu Ala Lys Thr Gly Asp Glu Leu Lys Val Thr Glu Ile Ser Asp 165 170 175 Asn Val Tyr Asp Ser Leu Lys Glu Asn Lys Xaa Xaa Glu Val His Val 180 185 190 Phe Gly Arg Arg Trp Pro Ser Thr Gly Gln Val His Pro Thr Gly Thr 195 200 205 Xaa Arg Thr Xaa Pro Leu Pro His His Gln Arg Gly Cys 210 215 220 <210> 83 <211> 672 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(649) <223> RXN00198 <400> 83 atgcaggatt agagcagcag caacggagcc agaatcagtc tcccaatttg atatccagcc 60 ccgcgctcct ttccagcgcg ccgattccac tccatggccg atg tac ccc aac ctc 115 Met Tyr Pro Asn Leu 1 5 ttc cgc acc gca acg gct cac gaa gaa ggc gaa tac atc atc act ggc 163 Phe Arg Thr Ala Thr Ala His Glu Glu Gly Glu Tyr Ile Ile Thr Gly 10 15 20 gat gaa tca gcc gat gaa atc gca gcc ctg ggc ctc gcc gaa cgt gcc 211 Asp Glu Ser Ala Asp Glu Ile Ala Ala Leu Gly Leu Ala Glu Arg Ala 25 30 35 gca ggc tcc acg ctt ggt gaa cgt aaa ttt gct gtc aac acc gtg gaa 259 Ala Gly Ser Thr Leu Gly Glu Arg Lys Phe Ala Val Asn Thr Val Glu 40 45 50 ttc cac ggc aac aac ggc cac gtc acc gga ctc acc ggc aac caa atc 307 Phe His Gly Asn Asn Gly His Val Thr Gly Leu Thr Gly Asn Gln Ile 55 60 65 cga gtt gtc aac ggc aaa cgt gaa cca atc gaa ggc acc gaa ttc ccc 355 Arg Val Val Asn Gly Lys Arg Glu Pro Ile Glu Gly Thr Glu Phe Pro 70 75 80 85 ttc gaa gca gac ctc gtt ctt gtt gca ctt ggc ttc acc ggc gca gaa 403 Phe Glu Ala Asp Leu Val Leu Val Ala Leu Gly Phe Thr Gly Ala Glu 90 95 100 caa ggc gga ttg gca cac gaa cta ggc gta ggt ttc gac gac cgg ggc 451 Gln Gly Gly Leu Ala His Glu Leu Gly Val Gly Phe Asp Asp Arg Gly 105 110 115 cgc atc ctc cgc gat tcc gaa tac cgc agc ccc acc aac tcc cgc gtt 499 Arg Ile Leu Arg Asp Ser Glu Tyr Arg Ser Pro Thr Asn Ser Arg Val 120 125 130 tac atc gca ggc gac aac ggc cgt ggc cag tcc ctg atc gtg tgg gca 547 Tyr Ile Ala Gly Asp Asn Gly Arg Gly Gln Ser Leu Ile Val Trp Ala 135 140 145 atc gcc gaa ggc cgc gca tgc gcc gca gct atc gac gcc gat ctc atg 595 Ile Ala Glu Gly Arg Ala Cys Ala Ala Ala Ile Asp Ala Asp Leu Met 150 155 160 165 ggt gaa act gca ctc cct gta gca gtt gca cca cag gac gtg ccg ctg 643 Gly Glu Thr Ala Leu Pro Val Ala Val Ala Pro Gln Asp Val Pro Leu 170 175 180 gct gtc tagcttgggt agaaaatgct aga 672 Ala Val <210> 84 <211> 183 <212> PRT <213> Corynebacterium glutamicum <400> 84 Met Tyr Pro Asn Leu Phe Arg Thr Ala Thr Ala His Glu Glu Gly Glu 1 5 10 15 Tyr Ile Ile Thr Gly Asp Glu Ser Ala Asp Glu Ile Ala Ala Leu Gly 20 25 30 Leu Ala Glu Arg Ala Ala Gly Ser Thr Leu Gly Glu Arg Lys Phe Ala 35 40 45 Val Asn Thr Val Glu Phe His Gly Asn Asn Gly His Val Thr Gly Leu 50 55 60 Thr Gly Asn Gln Ile Arg Val Val Asn Gly Lys Arg Glu Pro Ile Glu 65 70 75 80 Gly Thr Glu Phe Pro Phe Glu Ala Asp Leu Val Leu Val Ala Leu Gly 85 90 95 Phe Thr Gly Ala Glu Gln Gly Gly Leu Ala His Glu Leu Gly Val Gly 100 105 110 Phe Asp Asp Arg Gly Arg Ile Leu Arg Asp Ser Glu Tyr Arg Ser Pro 115 120 125 Thr Asn Ser Arg Val Tyr Ile Ala Gly Asp Asn Gly Arg Gly Gln Ser 130 135 140 Leu Ile Val Trp Ala Ile Ala Glu Gly Arg Ala Cys Ala Ala Ala Ile 145 150 155 160 Asp Ala Asp Leu Met Gly Glu Thr Ala Leu Pro Val Ala Val Ala Pro 165 170 175 Gln Asp Val Pro Leu Ala Val 180 <210> 85 <211> 305 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(282) <223> FRXA00198 <400> 85 ctc gtt ctt gtt gca ctt ggc ttc acc ggc gca gaa caa ggc gga ttg 48 Leu Val Leu Val Ala Leu Gly Phe Thr Gly Ala Glu Gln Gly Gly Leu 1 5 10 15 gca cac gaa cta ggc gta ggt ttc gac gac cgg ggc cgc atc ctc cgc 96 Ala His Glu Leu Gly Val Gly Phe Asp Asp Arg Gly Arg Ile Leu Arg 20 25 30 gat tcc gaa tac cgc agc ccc acc aac tcc cgc gtt tac atc gca ggc 144 Asp Ser Glu Tyr Arg Ser Pro Thr Asn Ser Arg Val Tyr Ile Ala Gly 35 40 45 gac aac ggc cgt ggc cag tcc ctg atc gtg tgg gca atc gcc gaa ggc 192 Asp Asn Gly Arg Gly Gln Ser Leu Ile Val Trp Ala Ile Ala Glu Gly 50 55 60 cgc gca tgc gcc gca gct atc gac gcc gat ctc atg ggt gaa act gca 240 Arg Ala Cys Ala Ala Ala Ile Asp Ala Asp Leu Met Gly Glu Thr Ala 65 70 75 80 ctc cct gta gca gtt gca cca cag gac gtg ccg ctg gct gtc 282 Leu Pro Val Ala Val Ala Pro Gln Asp Val Pro Leu Ala Val 85 90 tagcttgggt agaaaatgct aga 305 <210> 86 <211> 94 <212> PRT <213> Corynebacterium glutamicum <400> 86 Leu Val Leu Val Ala Leu Gly Phe Thr Gly Ala Glu Gln Gly Gly Leu 1 5 10 15 Ala His Glu Leu Gly Val Gly Phe Asp Asp Arg Gly Arg Ile Leu Arg 20 25 30 Asp Ser Glu Tyr Arg Ser Pro Thr Asn Ser Arg Val Tyr Ile Ala Gly 35 40 45 Asp Asn Gly Arg Gly Gln Ser Leu Ile Val Trp Ala Ile Ala Glu Gly 50 55 60 Arg Ala Cys Ala Ala Ala Ile Asp Ala Asp Leu Met Gly Glu Thr Ala 65 70 75 80 Leu Pro Val Ala Val Ala Pro Gln Asp Val Pro Leu Ala Val 85 90 <210> 87 <211> 727 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(727) <223> RXN00365 <400> 87 gaagcctacg atcgcttgca cgcgaccaac aatttccccg agttcaccgg ccgtttgtgc 60 cccgcaccct gcgaaggcgc ctgcgtgctc ggtatcaacg atg att ctg tca cca 115 Met Ile Leu Ser Pro 1 5 tca aaa acg ttt gag ctg gaa atc gtc gaa aaa gca ttc cgc gaa ggc 163 Ser Lys Thr Phe Glu Leu Glu Ile Val Glu Lys Ala Phe Arg Glu Gly 10 15 20 tgg gtg caa cca gta atc cca tcc atg tct acc ggg ctg tca gtc gcc 211 Trp Val Gln Pro Val Ile Pro Ser Met Ser Thr Gly Leu Ser Val Ala 25 30 35 gtc gtc ggt tcc ggc ccc gct ggc ctt gcc gcc gcg cag cag ctc acc 259 Val Val Gly Ser Gly Pro Ala Gly Leu Ala Ala Ala Gln Gln Leu Thr 40 45 50 cgc gca ggc cac agc gtt acc gtc ttt gaa cgc gac gac cgc ctc ggc 307 Arg Ala Gly His Ser Val Thr Val Phe Glu Arg Asp Asp Arg Leu Gly 55 60 65 ggc ctc atg cgc tac ggc gtg cca gaa tac aaa atg gag aac cgc tgg 355 Gly Leu Met Arg Tyr Gly Val Pro Glu Tyr Lys Met Glu Asn Arg Trp 70 75 80 85 atc gac cgc cgc atc gag caa atg gaa gca gag ggc aca act ttc cag 403 Ile Asp Arg Arg Ile Glu Gln Met Glu Ala Glu Gly Thr Thr Phe Gln 90 95 100 gta ggc acc tcg ccg cgc gcc gct gaa cta gcg ctt ttc gac gcg atc 451 Val Gly Thr Ser Pro Arg Ala Ala Glu Leu Ala Leu Phe Asp Ala Ile 105 110 115 ctc ctc gca acc ggc acc cca gtg gcc cgc gaa ctc tca gtt cca ggc 499 Leu Leu Ala Thr Gly Thr Pro Val Ala Arg Glu Leu Ser Val Pro Gly 120 125 130 cac gat ctc aac ggc atc cat gcg gca atg gat tac ctc acc gcc caa 547 His Asp Leu Asn Gly Ile His Ala Ala Met Asp Tyr Leu Thr Ala Gln 135 140 145 aac cgc atc aac gaa ggc gac ggt gaa gtc tct cca atc aac gcc aaa 595 Asn Arg Ile Asn Glu Gly Asp Gly Glu Val Ser Pro Ile Asn Ala Lys 150 155 160 165 ggc aag aaa gtt gtc atc atc ggt ggc ggc gac acc ggc acc gac tgc 643 Gly Lys Lys Val Val Ile Ile Gly Gly Gly Asp Thr Gly Thr Asp Cys 170 175 180 ttc ggc acc gca ctg cgc caa gga gca gaa tca gtc acc caa ttt gat 691 Phe Gly Thr Ala Leu Arg Gln Gly Ala Glu Ser Val Thr Gln Phe Asp 185 190 195 atc cgc ccc cgc gct cct ttc cag cgc gcc gat tcc 727 Ile Arg Pro Arg Ala Pro Phe Gln Arg Ala Asp Ser 200 205 <210> 88 <211> 209 <212> PRT <213> Corynebacterium glutamicum <400> 88 Met Ile Leu Ser Pro Ser Lys Thr Phe Glu Leu Glu Ile Val Glu Lys 1 5 10 15 Ala Phe Arg Glu Gly Trp Val Gln Pro Val Ile Pro Ser Met Ser Thr 20 25 30 Gly Leu Ser Val Ala Val Val Gly Ser Gly Pro Ala Gly Leu Ala Ala 35 40 45 Ala Gln Gln Leu Thr Arg Ala Gly His Ser Val Thr Val Phe Glu Arg 50 55 60 Asp Asp Arg Leu Gly Gly Leu Met Arg Tyr Gly Val Pro Glu Tyr Lys 65 70 75 80 Met Glu Asn Arg Trp Ile Asp Arg Arg Ile Glu Gln Met Glu Ala Glu 85 90 95 Gly Thr Thr Phe Gln Val Gly Thr Ser Pro Arg Ala Ala Glu Leu Ala 100 105 110 Leu Phe Asp Ala Ile Leu Leu Ala Thr Gly Thr Pro Val Ala Arg Glu 115 120 125 Leu Ser Val Pro Gly His Asp Leu Asn Gly Ile His Ala Ala Met Asp 130 135 140 Tyr Leu Thr Ala Gln Asn Arg Ile Asn Glu Gly Asp Gly Glu Val Ser 145 150 155 160 Pro Ile Asn Ala Lys Gly Lys Lys Val Val Ile Ile Gly Gly Gly Asp 165 170 175 Thr Gly Thr Asp Cys Phe Gly Thr Ala Leu Arg Gln Gly Ala Glu Ser 180 185 190 Val Thr Gln Phe Asp Ile Arg Pro Arg Ala Pro Phe Gln Arg Ala Asp 195 200 205 Ser <210> 89 <211> 727 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(727) <223> FRXA00365 <400> 89 gaagcctacg atcgcttgca cgcgaccaac aatttccccg agttcaccgg ccgtttgtgc 60 cccgcaccct gcgaaggcgc ctgcgtgctc ggtatcaacg atg att ctg tca cca 115 Met Ile Leu Ser Pro 1 5 tca aaa acg ttt gag ctg gaa atc gtc gaa aaa gca ttc cgc gaa ggc 163 Ser Lys Thr Phe Glu Leu Glu Ile Val Glu Lys Ala Phe Arg Glu Gly 10 15 20 tgg gtg caa cca gta atc cca tcc atg tct acc ggg ctg tca gtc gcc 211 Trp Val Gln Pro Val Ile Pro Ser Met Ser Thr Gly Leu Ser Val Ala 25 30 35 gtc gtc ggt tcc ggc ccc gct ggc ctt gcc gcc gcg cag cag ctc acc 259 Val Val Gly Ser Gly Pro Ala Gly Leu Ala Ala Ala Gln Gln Leu Thr 40 45 50 cgc gca ggc cac agc gtt acc gtc ttt gaa cgc gac gac cgc ctc ggc 307 Arg Ala Gly His Ser Val Thr Val Phe Glu Arg Asp Asp Arg Leu Gly 55 60 65 ggc ctc atg cgc tac ggc gtg cca gaa tac aaa atg gag aac cgc tgg 355 Gly Leu Met Arg Tyr Gly Val Pro Glu Tyr Lys Met Glu Asn Arg Trp 70 75 80 85 atc gac cgc cgc atc gag caa atg gaa gca gag ggc aca act ttc cag 403 Ile Asp Arg Arg Ile Glu Gln Met Glu Ala Glu Gly Thr Thr Phe Gln 90 95 100 gta ggc acc tcg ccg cgc gcc gct gaa cta gcg ctt ttc gac gcg atc 451 Val Gly Thr Ser Pro Arg Ala Ala Glu Leu Ala Leu Phe Asp Ala Ile 105 110 115 ctc ctc gca acc ggc acc cca gtg gcc cgc gaa ctc tca gtt cca ggc 499 Leu Leu Ala Thr Gly Thr Pro Val Ala Arg Glu Leu Ser Val Pro Gly 120 125 130 cac gat ctc aac ggc atc cat gcg gca atg gat tac ctc acc gcc caa 547 His Asp Leu Asn Gly Ile His Ala Ala Met Asp Tyr Leu Thr Ala Gln 135 140 145 aac cgc atc aac gaa ggc gac ggt gaa gtc tct cca atc aac gcc aaa 595 Asn Arg Ile Asn Glu Gly Asp Gly Glu Val Ser Pro Ile Asn Ala Lys 150 155 160 165 ggc aag aaa gtt gtc atc atc ggt ggc ggc gac acc ggc acc gac tgc 643 Gly Lys Lys Val Val Ile Ile Gly Gly Gly Asp Thr Gly Thr Asp Cys 170 175 180 ttc ggc acc gca ctg cgc caa gga gca gaa tca gtc acc caa ttt gat 691 Phe Gly Thr Ala Leu Arg Gln Gly Ala Glu Ser Val Thr Gln Phe Asp 185 190 195 atc cgc ccc cgc gct cct ttc cag cgc gcc gat tcc 727 Ile Arg Pro Arg Ala Pro Phe Gln Arg Ala Asp Ser 200 205 <210> 90 <211> 209 <212> PRT <213> Corynebacterium glutamicum <400> 90 Met Ile Leu Ser Pro Ser Lys Thr Phe Glu Leu Glu Ile Val Glu Lys 1 5 10 15 Ala Phe Arg Glu Gly Trp Val Gln Pro Val Ile Pro Ser Met Ser Thr 20 25 30 Gly Leu Ser Val Ala Val Val Gly Ser Gly Pro Ala Gly Leu Ala Ala 35 40 45 Ala Gln Gln Leu Thr Arg Ala Gly His Ser Val Thr Val Phe Glu Arg 50 55 60 Asp Asp Arg Leu Gly Gly Leu Met Arg Tyr Gly Val Pro Glu Tyr Lys 65 70 75 80 Met Glu Asn Arg Trp Ile Asp Arg Arg Ile Glu Gln Met Glu Ala Glu 85 90 95 Gly Thr Thr Phe Gln Val Gly Thr Ser Pro Arg Ala Ala Glu Leu Ala 100 105 110 Leu Phe Asp Ala Ile Leu Leu Ala Thr Gly Thr Pro Val Ala Arg Glu 115 120 125 Leu Ser Val Pro Gly His Asp Leu Asn Gly Ile His Ala Ala Met Asp 130 135 140 Tyr Leu Thr Ala Gln Asn Arg Ile Asn Glu Gly Asp Gly Glu Val Ser 145 150 155 160 Pro Ile Asn Ala Lys Gly Lys Lys Val Val Ile Ile Gly Gly Gly Asp 165 170 175 Thr Gly Thr Asp Cys Phe Gly Thr Ala Leu Arg Gln Gly Ala Glu Ser 180 185 190 Val Thr Gln Phe Asp Ile Arg Pro Arg Ala Pro Phe Gln Arg Ala Asp 195 200 205 Ser <210> 91 <211> 480 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(457) <223> RXA00366 <400> 91 aaatcatgcc gcgcgatttc caaaaagtac tcaacatcat cgaaacggcc cacgctgagg 60 gccaagaccc agcaatcaag atcatggagg cagtgagcta atg gcc gac cca caa 115 Met Ala Asp Pro Gln 1 5 gga ttc atc aaa tac tcc cga cgc gag cct gca cac cgc ccg gtc ccg 163 Gly Phe Ile Lys Tyr Ser Arg Arg Glu Pro Ala His Arg Pro Val Pro 10 15 20 ctg cgc ctc atg gac cac tcc gag gtc tac gaa aag gca ccg gca ggt 211 Leu Arg Leu Met Asp His Ser Glu Val Tyr Glu Lys Ala Pro Ala Gly 25 30 35 cag atc gag gaa cag gct gcc cgc tgc atg gat tgc ggt gtc ccg ttc 259 Gln Ile Glu Glu Gln Ala Ala Arg Cys Met Asp Cys Gly Val Pro Phe 40 45 50 tgc cac gaa ggc tgc cca ctg ggc aac atc atc cct gag tgg aat gat 307 Cys His Glu Gly Cys Pro Leu Gly Asn Ile Ile Pro Glu Trp Asn Asp 55 60 65 ctg gta cgc caa ggt cgg tgg aag gaa gcc tac gat cgc ttg cac gcg 355 Leu Val Arg Gln Gly Arg Trp Lys Glu Ala Tyr Asp Arg Leu His Ala 70 75 80 85 acc aac aat ttc ccc gag ttc acc ggc cgt ttg tgc ccc gca ccc tgc 403 Thr Asn Asn Phe Pro Glu Phe Thr Gly Arg Leu Cys Pro Ala Pro Cys 90 95 100 gaa ggc gcc tgc gtg ctc ggt atc aac gat gat tct gtc acc atc aaa 451 Glu Gly Ala Cys Val Leu Gly Ile Asn Asp Asp Ser Val Thr Ile Lys 105 110 115 aac gtt tgagctggaa atcgtcgaaa aag 480 Asn Val <210> 92 <211> 119 <212> PRT <213> Corynebacterium glutamicum <400> 92 Met Ala Asp Pro Gln Gly Phe Ile Lys Tyr Ser Arg Arg Glu Pro Ala 1 5 10 15 His Arg Pro Val Pro Leu Arg Leu Met Asp His Ser Glu Val Tyr Glu 20 25 30 Lys Ala Pro Ala Gly Gln Ile Glu Glu Gln Ala Ala Arg Cys Met Asp 35 40 45 Cys Gly Val Pro Phe Cys His Glu Gly Cys Pro Leu Gly Asn Ile Ile 50 55 60 Pro Glu Trp Asn Asp Leu Val Arg Gln Gly Arg Trp Lys Glu Ala Tyr 65 70 75 80 Asp Arg Leu His Ala Thr Asn Asn Phe Pro Glu Phe Thr Gly Arg Leu 85 90 95 Cys Pro Ala Pro Cys Glu Gly Ala Cys Val Leu Gly Ile Asn Asp Asp 100 105 110 Ser Val Thr Ile Lys Asn Val 115 <210> 93 <211> 1464 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1441) <223> RXA02072 <400> 93 tacatggtgc cctcaatggg aaccaccaac atcactaaat ggcccaggta cacactttaa 60 aatcgtgcgc gcatgcagcc gagatgggaa cgaggaaatc atg aca gtt gat gag 115 Met Thr Val Asp Glu 1 5 cag gtc tct aac tat tac gac atg ctt ctg aag cgc aat gct ggc gag 163 Gln Val Ser Asn Tyr Tyr Asp Met Leu Leu Lys Arg Asn Ala Gly Glu 10 15 20 cct gaa ttt cac cag gca gtg gca gag gtt ttg gaa tct ttg aag atc 211 Pro Glu Phe His Gln Ala Val Ala Glu Val Leu Glu Ser Leu Lys Ile 25 30 35 gtc ctg gaa aag gac cct cat tac gct gat tac ggt ctc atc cag cgc 259 Val Leu Glu Lys Asp Pro His Tyr Ala Asp Tyr Gly Leu Ile Gln Arg 40 45 50 ctg tgc gag cct gag cgt cag ctc atc ttc cgt gtg cct tgg gtt gat 307 Leu Cys Glu Pro Glu Arg Gln Leu Ile Phe Arg Val Pro Trp Val Asp 55 60 65 gac cag ggc cag gtc cac gtc aac cgt ggt ttc cgc gtg cag ttc aac 355 Asp Gln Gly Gln Val His Val Asn Arg Gly Phe Arg Val Gln Phe Asn 70 75 80 85 tct gca ctt gga cca tac aag ggc ggc ctg cgc ttc cac cca tct gta 403 Ser Ala Leu Gly Pro Tyr Lys Gly Gly Leu Arg Phe His Pro Ser Val 90 95 100 aac ctg ggc att gtg aag ttc ctg ggc ttt gag cag atc ttt aaa aac 451 Asn Leu Gly Ile Val Lys Phe Leu Gly Phe Glu Gln Ile Phe Lys Asn 105 110 115 tcc cta acc ggc ctg cca atc ggt ggt ggc aag ggt gga tcc gac ttc 499 Ser Leu Thr Gly Leu Pro Ile Gly Gly Gly Lys Gly Gly Ser Asp Phe 120 125 130 gac cct aag ggc aag tcc gat ctg gaa atc atg cgt ttc tgc cag tcc 547 Asp Pro Lys Gly Lys Ser Asp Leu Glu Ile Met Arg Phe Cys Gln Ser 135 140 145 ttc atg acc gag ctg cac cgc cac atc ggt gag tac cgc gac gtt cct 595 Phe Met Thr Glu Leu His Arg His Ile Gly Glu Tyr Arg Asp Val Pro 150 155 160 165 gca ggt aac atc gga gtt ggt ggc cac gag atc ggt tac ctg ttt ggc 643 Ala Gly Asn Ile Gly Val Gly Gly His Glu Ile Gly Tyr Leu Phe Gly 170 175 180 cac tac cgt cgc atg gct aac cag cac gag tcc ggc gtt ttg acc ggt 691 His Tyr Arg Arg Met Ala Asn Gln His Glu Ser Gly Val Leu Thr Gly 185 190 195 aag ggc ctg acc tgg ggt gga tcc ctg gtc cgc acc gag gca act ggc 739 Lys Gly Leu Thr Trp Gly Gly Ser Leu Val Arg Thr Glu Ala Thr Gly 200 205 210 tac ggc tgc gtt tac ttc gtg agt gaa atg atc aag gct aag ggc gag 787 Tyr Gly Cys Val Tyr Phe Val Ser Glu Met Ile Lys Ala Lys Gly Glu 215 220 225 agc atc agc ggc cag aag atc atc gtt tcc ggt tcc ggc aac gta gca 835 Ser Ile Ser Gly Gln Lys Ile Ile Val Ser Gly Ser Gly Asn Val Ala 230 235 240 245 acc tac gcg att gaa aag gct cag gaa ctc ggc gca acc gtt att ggt 883 Thr Tyr Ala Ile Glu Lys Ala Gln Glu Leu Gly Ala Thr Val Ile Gly 250 255 260 ttc tcc gat tcc agc ggt tgg gtt cat acc cct aac ggc gtt gac gtg 931 Phe Ser Asp Ser Ser Gly Trp Val His Thr Pro Asn Gly Val Asp Val 265 270 275 gct aag ctc cgc gaa atc aag gaa gtt cgt cgc gca cgc gta tcc gtg 979 Ala Lys Leu Arg Glu Ile Lys Glu Val Arg Arg Ala Arg Val Ser Val 280 285 290 tac gcc gac gaa gtt gaa ggc gca acc tac cac acc gac ggt tcc atc 1027 Tyr Ala Asp Glu Val Glu Gly Ala Thr Tyr His Thr Asp Gly Ser Ile 295 300 305 tgg gat ctc aag tgc gat atc gct ctt cct tgt gca act cag aac gag 1075 Trp Asp Leu Lys Cys Asp Ile Ala Leu Pro Cys Ala Thr Gln Asn Glu 310 315 320 325 ctc aac ggc gag aac gct aag act ctt gca gac aac ggc tgc cgt ttc 1123 Leu Asn Gly Glu Asn Ala Lys Thr Leu Ala Asp Asn Gly Cys Arg Phe 330 335 340 gtt gct gaa ggc gcg aac atg cct tcc acc cct gag gct gtt gag gtc 1171 Val Ala Glu Gly Ala Asn Met Pro Ser Thr Pro Glu Ala Val Glu Val 345 350 355 ttc cgt gag cgc gac atc cgc ttc gga cca ggc aag gca gct aac gct 1219 Phe Arg Glu Arg Asp Ile Arg Phe Gly Pro Gly Lys Ala Ala Asn Ala 360 365 370 ggt ggc gtt gca acc tcc gct ctg gag atg cag cag aac gct tcg cgc 1267 Gly Gly Val Ala Thr Ser Ala Leu Glu Met Gln Gln Asn Ala Ser Arg 375 380 385 gat tcc tgg agc ttc gag tac acc gac gag cgc ctc cag gtg atc atg 1315 Asp Ser Trp Ser Phe Glu Tyr Thr Asp Glu Arg Leu Gln Val Ile Met 390 395 400 405 aag aac atc ttc aag acc tgt gca gag acc gca gca gag tat gga cac 1363 Lys Asn Ile Phe Lys Thr Cys Ala Glu Thr Ala Ala Glu Tyr Gly His 410 415 420 gag aac gat tac gtt gtc ggc gct aac att gct ggc ttc aag aag gta 1411 Glu Asn Asp Tyr Val Val Gly Ala Asn Ile Ala Gly Phe Lys Lys Val 425 430 435 gct gac gcg atg ctg gca cag ggc gtc atc taagacccct gcgctttact 1461 Ala Asp Ala Met Leu Ala Gln Gly Val Ile 440 445 taa 1464 <210> 94 <211> 447 <212> PRT <213> Corynebacterium glutamicum <400> 94 Met Thr Val Asp Glu Gln Val Ser Asn Tyr Tyr Asp Met Leu Leu Lys 1 5 10 15 Arg Asn Ala Gly Glu Pro Glu Phe His Gln Ala Val Ala Glu Val Leu 20 25 30 Glu Ser Leu Lys Ile Val Leu Glu Lys Asp Pro His Tyr Ala Asp Tyr 35 40 45 Gly Leu Ile Gln Arg Leu Cys Glu Pro Glu Arg Gln Leu Ile Phe Arg 50 55 60 Val Pro Trp Val Asp Asp Gln Gly Gln Val His Val Asn Arg Gly Phe 65 70 75 80 Arg Val Gln Phe Asn Ser Ala Leu Gly Pro Tyr Lys Gly Gly Leu Arg 85 90 95 Phe His Pro Ser Val Asn Leu Gly Ile Val Lys Phe Leu Gly Phe Glu 100 105 110 Gln Ile Phe Lys Asn Ser Leu Thr Gly Leu Pro Ile Gly Gly Gly Lys 115 120 125 Gly Gly Ser Asp Phe Asp Pro Lys Gly Lys Ser Asp Leu Glu Ile Met 130 135 140 Arg Phe Cys Gln Ser Phe Met Thr Glu Leu His Arg His Ile Gly Glu 145 150 155 160 Tyr Arg Asp Val Pro Ala Gly Asn Ile Gly Val Gly Gly His Glu Ile 165 170 175 Gly Tyr Leu Phe Gly His Tyr Arg Arg Met Ala Asn Gln His Glu Ser 180 185 190 Gly Val Leu Thr Gly Lys Gly Leu Thr Trp Gly Gly Ser Leu Val Arg 195 200 205 Thr Glu Ala Thr Gly Tyr Gly Cys Val Tyr Phe Val Ser Glu Met Ile 210 215 220 Lys Ala Lys Gly Glu Ser Ile Ser Gly Gln Lys Ile Ile Val Ser Gly 225 230 235 240 Ser Gly Asn Val Ala Thr Tyr Ala Ile Glu Lys Ala Gln Glu Leu Gly 245 250 255 Ala Thr Val Ile Gly Phe Ser Asp Ser Ser Gly Trp Val His Thr Pro 260 265 270 Asn Gly Val Asp Val Ala Lys Leu Arg Glu Ile Lys Glu Val Arg Arg 275 280 285 Ala Arg Val Ser Val Tyr Ala Asp Glu Val Glu Gly Ala Thr Tyr His 290 295 300 Thr Asp Gly Ser Ile Trp Asp Leu Lys Cys Asp Ile Ala Leu Pro Cys 305 310 315 320 Ala Thr Gln Asn Glu Leu Asn Gly Glu Asn Ala Lys Thr Leu Ala Asp 325 330 335 Asn Gly Cys Arg Phe Val Ala Glu Gly Ala Asn Met Pro Ser Thr Pro 340 345 350 Glu Ala Val Glu Val Phe Arg Glu Arg Asp Ile Arg Phe Gly Pro Gly 355 360 365 Lys Ala Ala Asn Ala Gly Gly Val Ala Thr Ser Ala Leu Glu Met Gln 370 375 380 Gln Asn Ala Ser Arg Asp Ser Trp Ser Phe Glu Tyr Thr Asp Glu Arg 385 390 395 400 Leu Gln Val Ile Met Lys Asn Ile Phe Lys Thr Cys Ala Glu Thr Ala 405 410 415 Ala Glu Tyr Gly His Glu Asn Asp Tyr Val Val Gly Ala Asn Ile Ala 420 425 430 Gly Phe Lys Lys Val Ala Asp Ala Met Leu Ala Gln Gly Val Ile 435 440 445 <210> 95 <211> 1461 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1438) <223> RXA00323 <400> 95 cgcgacatcc ttgagtaact ctgagaaaaa ctacccccga tgggagtata aaagtggcaa 60 atgcgcagtc gatgtcccat cgctgcgtag attagttttc atg aac agc gaa cag 115 Met Asn Ser Glu Gln 1 5 gaa ttt gta ctc agc gcc att gaa gaa cgc gac att aag ttt gtg cgt 163 Glu Phe Val Leu Ser Ala Ile Glu Glu Arg Asp Ile Lys Phe Val Arg 10 15 20 cta tgg ttc act gac att ctt ggc cac ttg aag tca gtg gtt gtg gct 211 Leu Trp Phe Thr Asp Ile Leu Gly His Leu Lys Ser Val Val Val Ala 25 30 35 cct gca gaa cta gag tct gcg ttg gaa gaa ggc atc gga ttc gat ggc 259 Pro Ala Glu Leu Glu Ser Ala Leu Glu Glu Gly Ile Gly Phe Asp Gly 40 45 50 tca gcc att gag ggc tac gcg cgt atc tcg gaa gcg gac acc att gcc 307 Ser Ala Ile Glu Gly Tyr Ala Arg Ile Ser Glu Ala Asp Thr Ile Ala 55 60 65 cgc cca gat cca tcg aca ttc cag gtc ctc cca cta gaa gcg ggc atc 355 Arg Pro Asp Pro Ser Thr Phe Gln Val Leu Pro Leu Glu Ala Gly Ile 70 75 80 85 tca aaa ctg cag gca gca cgc ctg ttt tgc gat gtc acg atg cca gac 403 Ser Lys Leu Gln Ala Ala Arg Leu Phe Cys Asp Val Thr Met Pro Asp 90 95 100 gga cag cca tct ttt tct gac ccg cgc caa gtg ctg cgc agg cag gtc 451 Gly Gln Pro Ser Phe Ser Asp Pro Arg Gln Val Leu Arg Arg Gln Val 105 110 115 caa cta gct gca gat gaa ggc ttg acc tgc atg atc tca cca gag att 499 Gln Leu Ala Ala Asp Glu Gly Leu Thr Cys Met Ile Ser Pro Glu Ile 120 125 130 gag ttc tat ttg gtg caa agc ctt cgc acc aac gga ctg cca cct gtg 547 Glu Phe Tyr Leu Val Gln Ser Leu Arg Thr Asn Gly Leu Pro Pro Val 135 140 145 ccc act gac aac ggc gga tat ttc gac caa gcc aca ttc aat gag gcg 595 Pro Thr Asp Asn Gly Gly Tyr Phe Asp Gln Ala Thr Phe Asn Glu Ala 150 155 160 165 ccg aat ttc cgt cga aac gcg atg gta gcg ctg gag gaa ctc ggc atc 643 Pro Asn Phe Arg Arg Asn Ala Met Val Ala Leu Glu Glu Leu Gly Ile 170 175 180 cct gtc gag ttc tcc cac cat gaa act gca cct ggc cag caa gaa atc 691 Pro Val Glu Phe Ser His His Glu Thr Ala Pro Gly Gln Gln Glu Ile 185 190 195 gat tta cgc cat gcg gat gcg ctc acc atg gcc gac aac atc atg acc 739 Asp Leu Arg His Ala Asp Ala Leu Thr Met Ala Asp Asn Ile Met Thr 200 205 210 ttc cgc tac atc atg aaa cag gtg gca agg gac caa ggc gtc ggg gca 787 Phe Arg Tyr Ile Met Lys Gln Val Ala Arg Asp Gln Gly Val Gly Ala 215 220 225 tca ttt atg ccc aag cca ttc caa gaa cat gca ggc tcc gcc atg cac 835 Ser Phe Met Pro Lys Pro Phe Gln Glu His Ala Gly Ser Ala Met His 230 235 240 245 acg cac atg tcc tta ttt gag ggc gat acc aac gcg ttc cac gat cca 883 Thr His Met Ser Leu Phe Glu Gly Asp Thr Asn Ala Phe His Asp Pro 250 255 260 gac gat tct tac atg ctg tcc aaa acc gca aaa cag ttc atc gct gga 931 Asp Asp Ser Tyr Met Leu Ser Lys Thr Ala Lys Gln Phe Ile Ala Gly 265 270 275 atc ttg cat cac gct cca gaa ttc acc gct gtg acc aac cag tgg gtc 979 Ile Leu His His Ala Pro Glu Phe Thr Ala Val Thr Asn Gln Trp Val 280 285 290 aat tcc tac aaa cgc atc gtg tac gga aac gaa gct cca act gcg gca 1027 Asn Ser Tyr Lys Arg Ile Val Tyr Gly Asn Glu Ala Pro Thr Ala Ala 295 300 305 acc tgg ggt gta tct aat cgt tct gcg ctg gtt cgt gtt cct acc tac 1075 Thr Trp Gly Val Ser Asn Arg Ser Ala Leu Val Arg Val Pro Thr Tyr 310 315 320 325 cgt ttg aat aag gag gag tcg cgc cgg gtg gag gtg cgt ctt cct gat 1123 Arg Leu Asn Lys Glu Glu Ser Arg Arg Val Glu Val Arg Leu Pro Asp 330 335 340 acc gct tgt aac cca tat ttg gcg ttt tca gtg atg ctc ggc gct ggt 1171 Thr Ala Cys Asn Pro Tyr Leu Ala Phe Ser Val Met Leu Gly Ala Gly 345 350 355 ttg aaa ggc att aaa gaa ggt tat gag ctc gac gag cca gct gag gac 1219 Leu Lys Gly Ile Lys Glu Gly Tyr Glu Leu Asp Glu Pro Ala Glu Asp 360 365 370 gat atc tcc aac ttg agc ttc cgg gaa cgt cgc gcc atg ggc tac aac 1267 Asp Ile Ser Asn Leu Ser Phe Arg Glu Arg Arg Ala Met Gly Tyr Asn 375 380 385 gat ctg cca agc agc ctt gat cag gca ctg cgc caa atg gaa aag tca 1315 Asp Leu Pro Ser Ser Leu Asp Gln Ala Leu Arg Gln Met Glu Lys Ser 390 395 400 405 gag ctt gtt gct gac atc ctc ggt gag cac gtt ttt gag ttt ttc ttg 1363 Glu Leu Val Ala Asp Ile Leu Gly Glu His Val Phe Glu Phe Phe Leu 410 415 420 cgc aat aag tgg cgt gaa tgg cgt gac tac caa gag cag atc act ccg 1411 Arg Asn Lys Trp Arg Glu Trp Arg Asp Tyr Gln Glu Gln Ile Thr Pro 425 430 435 tgg gag ctc cga aac aat ctt gat tac tagacttttg cactccaatg 1458 Trp Glu Leu Arg Asn Asn Leu Asp Tyr 440 445 gaa 1461 <210> 96 <211> 446 <212> PRT <213> Corynebacterium glutamicum <400> 96 Met Asn Ser Glu Gln Glu Phe Val Leu Ser Ala Ile Glu Glu Arg Asp 1 5 10 15 Ile Lys Phe Val Arg Leu Trp Phe Thr Asp Ile Leu Gly His Leu Lys 20 25 30 Ser Val Val Val Ala Pro Ala Glu Leu Glu Ser Ala Leu Glu Glu Gly 35 40 45 Ile Gly Phe Asp Gly Ser Ala Ile Glu Gly Tyr Ala Arg Ile Ser Glu 50 55 60 Ala Asp Thr Ile Ala Arg Pro Asp Pro Ser Thr Phe Gln Val Leu Pro 65 70 75 80 Leu Glu Ala Gly Ile Ser Lys Leu Gln Ala Ala Arg Leu Phe Cys Asp 85 90 95 Val Thr Met Pro Asp Gly Gln Pro Ser Phe Ser Asp Pro Arg Gln Val 100 105 110 Leu Arg Arg Gln Val Gln Leu Ala Ala Asp Glu Gly Leu Thr Cys Met 115 120 125 Ile Ser Pro Glu Ile Glu Phe Tyr Leu Val Gln Ser Leu Arg Thr Asn 130 135 140 Gly Leu Pro Pro Val Pro Thr Asp Asn Gly Gly Tyr Phe Asp Gln Ala 145 150 155 160 Thr Phe Asn Glu Ala Pro Asn Phe Arg Arg Asn Ala Met Val Ala Leu 165 170 175 Glu Glu Leu Gly Ile Pro Val Glu Phe Ser His His Glu Thr Ala Pro 180 185 190 Gly Gln Gln Glu Ile Asp Leu Arg His Ala Asp Ala Leu Thr Met Ala 195 200 205 Asp Asn Ile Met Thr Phe Arg Tyr Ile Met Lys Gln Val Ala Arg Asp 210 215 220 Gln Gly Val Gly Ala Ser Phe Met Pro Lys Pro Phe Gln Glu His Ala 225 230 235 240 Gly Ser Ala Met His Thr His Met Ser Leu Phe Glu Gly Asp Thr Asn 245 250 255 Ala Phe His Asp Pro Asp Asp Ser Tyr Met Leu Ser Lys Thr Ala Lys 260 265 270 Gln Phe Ile Ala Gly Ile Leu His His Ala Pro Glu Phe Thr Ala Val 275 280 285 Thr Asn Gln Trp Val Asn Ser Tyr Lys Arg Ile Val Tyr Gly Asn Glu 290 295 300 Ala Pro Thr Ala Ala Thr Trp Gly Val Ser Asn Arg Ser Ala Leu Val 305 310 315 320 Arg Val Pro Thr Tyr Arg Leu Asn Lys Glu Glu Ser Arg Arg Val Glu 325 330 335 Val Arg Leu Pro Asp Thr Ala Cys Asn Pro Tyr Leu Ala Phe Ser Val 340 345 350 Met Leu Gly Ala Gly Leu Lys Gly Ile Lys Glu Gly Tyr Glu Leu Asp 355 360 365 Glu Pro Ala Glu Asp Asp Ile Ser Asn Leu Ser Phe Arg Glu Arg Arg 370 375 380 Ala Met Gly Tyr Asn Asp Leu Pro Ser Ser Leu Asp Gln Ala Leu Arg 385 390 395 400 Gln Met Glu Lys Ser Glu Leu Val Ala Asp Ile Leu Gly Glu His Val 405 410 415 Phe Glu Phe Phe Leu Arg Asn Lys Trp Arg Glu Trp Arg Asp Tyr Gln 420 425 430 Glu Gln Ile Thr Pro Trp Glu Leu Arg Asn Asn Leu Asp Tyr 435 440 445 <210> 97 <211> 1554 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1531) <223> RXA00335 <400> 97 actacatttg cagccaagtc tactacttga tcttcaaagg tcagcaattg tgaacaaagc 60 tacaaataaa ccgttccgcc catgtcaatg aggagtcacc gtg gcg ttt gaa acc 115 Val Ala Phe Glu Thr 1 5 ccg gaa gaa att gtc aag ttc atc aag gat gaa aac gtc gag ttc gtt 163 Pro Glu Glu Ile Val Lys Phe Ile Lys Asp Glu Asn Val Glu Phe Val 10 15 20 gac gtt cga ttc acc gac ctt ccc ggc acc gag cag cac ttc agc atc 211 Asp Val Arg Phe Thr Asp Leu Pro Gly Thr Glu Gln His Phe Ser Ile 25 30 35 cca gct gcc agc ttc gat gca gat aca atc gaa gaa ggt ctc gca ttc 259 Pro Ala Ala Ser Phe Asp Ala Asp Thr Ile Glu Glu Gly Leu Ala Phe 40 45 50 gac gga tcc tcg atc cgt ggc ttc acc acg atc gac gaa tct gac atg 307 Asp Gly Ser Ser Ile Arg Gly Phe Thr Thr Ile Asp Glu Ser Asp Met 55 60 65 aat ctc ctg cca gac ctc gga acg gcc acc ctt gat cca ttc cgc aag 355 Asn Leu Leu Pro Asp Leu Gly Thr Ala Thr Leu Asp Pro Phe Arg Lys 70 75 80 85 gca aag acc ctg aac gtt aag ttc ttc gtt cac gat cct ttc acc cgc 403 Ala Lys Thr Leu Asn Val Lys Phe Phe Val His Asp Pro Phe Thr Arg 90 95 100 gag gca ttc tcc cgc gac cca cgc aac gtg gca cgc aag gca gag cag 451 Glu Ala Phe Ser Arg Asp Pro Arg Asn Val Ala Arg Lys Ala Glu Gln 105 110 115 tac ctg gca tcc acc ggc att gca gac acc tgc aac ttc ggc gcc gag 499 Tyr Leu Ala Ser Thr Gly Ile Ala Asp Thr Cys Asn Phe Gly Ala Glu 120 125 130 gct gag ttc tac ctc ttc gac tcc gtt cgc tac tcc acc gag atg aac 547 Ala Glu Phe Tyr Leu Phe Asp Ser Val Arg Tyr Ser Thr Glu Met Asn 135 140 145 tcc ggc ttc tac gaa gta gat acc gaa gaa ggc tgg tgg aac cgt ggc 595 Ser Gly Phe Tyr Glu Val Asp Thr Glu Glu Gly Trp Trp Asn Arg Gly 150 155 160 165 aag gaa acc aac ctc gac ggc acc cca aac ctg ggc gca aag aac cgc 643 Lys Glu Thr Asn Leu Asp Gly Thr Pro Asn Leu Gly Ala Lys Asn Arg 170 175 180 gtc aag ggt ggc tac ttc cca gta gca cca tac gac caa acc gtt gac 691 Val Lys Gly Gly Tyr Phe Pro Val Ala Pro Tyr Asp Gln Thr Val Asp 185 190 195 gtg cgc gat gac atg gtt cgc aac ctc gca gct tcc ggc ttc gct ctt 739 Val Arg Asp Asp Met Val Arg Asn Leu Ala Ala Ser Gly Phe Ala Leu 200 205 210 gag cgt ttc cac cac gaa gtc ggt ggc gga cag cag gaa atc aac tac 787 Glu Arg Phe His His Glu Val Gly Gly Gly Gln Gln Glu Ile Asn Tyr 215 220 225 cgc ttc aac acc atg ctc cac gcg gca gat gat atc cag acc ttc aag 835 Arg Phe Asn Thr Met Leu His Ala Ala Asp Asp Ile Gln Thr Phe Lys 230 235 240 245 tac atc atc aag aac acc gct cgc ctc cac ggc aag gct gca acc ttc 883 Tyr Ile Ile Lys Asn Thr Ala Arg Leu His Gly Lys Ala Ala Thr Phe 250 255 260 atg cct aag cca ctg gct ggc gac aac ggt tcc ggc atg cac gct cac 931 Met Pro Lys Pro Leu Ala Gly Asp Asn Gly Ser Gly Met His Ala His 265 270 275 cag tcc ctc tgg aag gac ggc aag cca ctc ttc cac gat gag tcc ggc 979 Gln Ser Leu Trp Lys Asp Gly Lys Pro Leu Phe His Asp Glu Ser Gly 280 285 290 tac gca ggc ctg tcc gac atc gcc cgc tac tac atc ggc ggc atc ctg 1027 Tyr Ala Gly Leu Ser Asp Ile Ala Arg Tyr Tyr Ile Gly Gly Ile Leu 295 300 305 cac cac gca ggc gct gtt ctg gcg ttc acc aac gca acc ctg aac tcc 1075 His His Ala Gly Ala Val Leu Ala Phe Thr Asn Ala Thr Leu Asn Ser 310 315 320 325 tac cac cgt ctg gtt cca ggc ttc gag gct cca atc aac ctg gtg tac 1123 Tyr His Arg Leu Val Pro Gly Phe Glu Ala Pro Ile Asn Leu Val Tyr 330 335 340 tca cag cgc aac cgt tcc gct gct gtc cgt atc cca atc acc gga tcc 1171 Ser Gln Arg Asn Arg Ser Ala Ala Val Arg Ile Pro Ile Thr Gly Ser 345 350 355 aac ccg aag gca aag cgc atc gaa ttc cgc gct cca gac cca tca ggc 1219 Asn Pro Lys Ala Lys Arg Ile Glu Phe Arg Ala Pro Asp Pro Ser Gly 360 365 370 aac cca tac ctg ggc ttt gca gcg atg atg atg gcc ggc ctc gac ggc 1267 Asn Pro Tyr Leu Gly Phe Ala Ala Met Met Met Ala Gly Leu Asp Gly 375 380 385 atc aag aac cgc atc gag cca cac gct cca gtg gac aag gac ctc tac 1315 Ile Lys Asn Arg Ile Glu Pro His Ala Pro Val Asp Lys Asp Leu Tyr 390 395 400 405 gaa cta cca cca gag gaa gct gca tcc att cca cag gca cca acc tcc 1363 Glu Leu Pro Pro Glu Glu Ala Ala Ser Ile Pro Gln Ala Pro Thr Ser 410 415 420 ctg gaa gca tcc ctg aag gca ctg cag gaa gac acc gac ttc ctc acc 1411 Leu Glu Ala Ser Leu Lys Ala Leu Gln Glu Asp Thr Asp Phe Leu Thr 425 430 435 gag tct gac gtc ttc acc gag gat ctc atc gag gcg tac atc cag tac 1459 Glu Ser Asp Val Phe Thr Glu Asp Leu Ile Glu Ala Tyr Ile Gln Tyr 440 445 450 aag tac gac aac gag atc tcc cca gtt cgc ctg cgc cca acc ccg cag 1507 Lys Tyr Asp Asn Glu Ile Ser Pro Val Arg Leu Arg Pro Thr Pro Gln 455 460 465 gaa ttc gaa ttg tac ttc gac tgc taattcactt agctagccga tag 1554 Glu Phe Glu Leu Tyr Phe Asp Cys 470 475 <210> 98 <211> 477 <212> PRT <213> Corynebacterium glutamicum <400> 98 Val Ala Phe Glu Thr Pro Glu Glu Ile Val Lys Phe Ile Lys Asp Glu 1 5 10 15 Asn Val Glu Phe Val Asp Val Arg Phe Thr Asp Leu Pro Gly Thr Glu 20 25 30 Gln His Phe Ser Ile Pro Ala Ala Ser Phe Asp Ala Asp Thr Ile Glu 35 40 45 Glu Gly Leu Ala Phe Asp Gly Ser Ser Ile Arg Gly Phe Thr Thr Ile 50 55 60 Asp Glu Ser Asp Met Asn Leu Leu Pro Asp Leu Gly Thr Ala Thr Leu 65 70 75 80 Asp Pro Phe Arg Lys Ala Lys Thr Leu Asn Val Lys Phe Phe Val His 85 90 95 Asp Pro Phe Thr Arg Glu Ala Phe Ser Arg Asp Pro Arg Asn Val Ala 100 105 110 Arg Lys Ala Glu Gln Tyr Leu Ala Ser Thr Gly Ile Ala Asp Thr Cys 115 120 125 Asn Phe Gly Ala Glu Ala Glu Phe Tyr Leu Phe Asp Ser Val Arg Tyr 130 135 140 Ser Thr Glu Met Asn Ser Gly Phe Tyr Glu Val Asp Thr Glu Glu Gly 145 150 155 160 Trp Trp Asn Arg Gly Lys Glu Thr Asn Leu Asp Gly Thr Pro Asn Leu 165 170 175 Gly Ala Lys Asn Arg Val Lys Gly Gly Tyr Phe Pro Val Ala Pro Tyr 180 185 190 Asp Gln Thr Val Asp Val Arg Asp Asp Met Val Arg Asn Leu Ala Ala 195 200 205 Ser Gly Phe Ala Leu Glu Arg Phe His His Glu Val Gly Gly Gly Gln 210 215 220 Gln Glu Ile Asn Tyr Arg Phe Asn Thr Met Leu His Ala Ala Asp Asp 225 230 235 240 Ile Gln Thr Phe Lys Tyr Ile Ile Lys Asn Thr Ala Arg Leu His Gly 245 250 255 Lys Ala Ala Thr Phe Met Pro Lys Pro Leu Ala Gly Asp Asn Gly Ser 260 265 270 Gly Met His Ala His Gln Ser Leu Trp Lys Asp Gly Lys Pro Leu Phe 275 280 285 His Asp Glu Ser Gly Tyr Ala Gly Leu Ser Asp Ile Ala Arg Tyr Tyr 290 295 300 Ile Gly Gly Ile Leu His His Ala Gly Ala Val Leu Ala Phe Thr Asn 305 310 315 320 Ala Thr Leu Asn Ser Tyr His Arg Leu Val Pro Gly Phe Glu Ala Pro 325 330 335 Ile Asn Leu Val Tyr Ser Gln Arg Asn Arg Ser Ala Ala Val Arg Ile 340 345 350 Pro Ile Thr Gly Ser Asn Pro Lys Ala Lys Arg Ile Glu Phe Arg Ala 355 360 365 Pro Asp Pro Ser Gly Asn Pro Tyr Leu Gly Phe Ala Ala Met Met Met 370 375 380 Ala Gly Leu Asp Gly Ile Lys Asn Arg Ile Glu Pro His Ala Pro Val 385 390 395 400 Asp Lys Asp Leu Tyr Glu Leu Pro Pro Glu Glu Ala Ala Ser Ile Pro 405 410 415 Gln Ala Pro Thr Ser Leu Glu Ala Ser Leu Lys Ala Leu Gln Glu Asp 420 425 430 Thr Asp Phe Leu Thr Glu Ser Asp Val Phe Thr Glu Asp Leu Ile Glu 435 440 445 Ala Tyr Ile Gln Tyr Lys Tyr Asp Asn Glu Ile Ser Pro Val Arg Leu 450 455 460 Arg Pro Thr Pro Gln Glu Phe Glu Leu Tyr Phe Asp Cys 465 470 475 <210> 99 <211> 3258 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3235) <223> RXA00324 <400> 99 tccgtgggag ctccgaaaca atcttgatta ctagactttt gcactccaat ggaaacccta 60 cggcgaccca attgcgaccc gatgaaggag gggagaagct atg tca gga ccg tta 115 Met Ser Gly Pro Leu 1 5 aga agt gaa cgt aaa gtc gtt ggc ttt gtc aga gac cca ctg cca aaa 163 Arg Ser Glu Arg Lys Val Val Gly Phe Val Arg Asp Pro Leu Pro Lys 10 15 20 gtt ggt tct tta tcg ctg aaa tct gag cat gcc caa gca gat cta gag 211 Val Gly Ser Leu Ser Leu Lys Ser Glu His Ala Gln Ala Asp Leu Glu 25 30 35 cat ttg ggt tgg cgc aat gtt gag tct ttg gat ttg ttg tgg ggc ttg 259 His Leu Gly Trp Arg Asn Val Glu Ser Leu Asp Leu Leu Trp Gly Leu 40 45 50 tca ggt gca ggc gat ccc gat gtc gcg ctg aac ctt ctt att cgg ctg 307 Ser Gly Ala Gly Asp Pro Asp Val Ala Leu Asn Leu Leu Ile Arg Leu 55 60 65 tat cag gca ctt gaa gca atc ggc gag gat gct cga aac gag ctt gat 355 Tyr Gln Ala Leu Glu Ala Ile Gly Glu Asp Ala Arg Asn Glu Leu Asp 70 75 80 85 caa gag att cgc cag gat gaa aaa cta cga gtc cgc ctt ttt gca ttg 403 Gln Glu Ile Arg Gln Asp Glu Lys Leu Arg Val Arg Leu Phe Ala Leu 90 95 100 ttg ggt ggt tcc tcg gct gtc ggt gat cac ttg gtc gcc aat cct ttg 451 Leu Gly Gly Ser Ser Ala Val Gly Asp His Leu Val Ala Asn Pro Leu 105 110 115 cag tgg aaa ctc tta aaa ctt gat gcg cca tcg agg gaa gag atg ttt 499 Gln Trp Lys Leu Leu Lys Leu Asp Ala Pro Ser Arg Glu Glu Met Phe 120 125 130 cag gcg ctg ctg gaa tct gtg aaa gct cag cct gct gtg ctt gag gtt 547 Gln Ala Leu Leu Glu Ser Val Lys Ala Gln Pro Ala Val Leu Glu Val 135 140 145 gag gat ttc agc gat gca cac aac att gcc cga gac gat ttg agc acg 595 Glu Asp Phe Ser Asp Ala His Asn Ile Ala Arg Asp Asp Leu Ser Thr 150 155 160 165 cct ggt ttt tac acg gct agt gtt acc ggg cct gaa gca gag cga gtc 643 Pro Gly Phe Tyr Thr Ala Ser Val Thr Gly Pro Glu Ala Glu Arg Val 170 175 180 ttg aaa tgg act tat cgc acg ttg ctg acc cgg att gct gcg cat gat 691 Leu Lys Trp Thr Tyr Arg Thr Leu Leu Thr Arg Ile Ala Ala His Asp 185 190 195 tta gcg ggt acc tat ccc acc gac atg cgg aga aaa ggt ggc gat cct 739 Leu Ala Gly Thr Tyr Pro Thr Asp Met Arg Arg Lys Gly Gly Asp Pro 200 205 210 gtt ccg ttt agc aca gtg acc atg cag ctc agc gac cta gct gat gct 787 Val Pro Phe Ser Thr Val Thr Met Gln Leu Ser Asp Leu Ala Asp Ala 215 220 225 gct ttg act gct gct tta gct gtg gca att gcc aat gtt tat ggt gaa 835 Ala Leu Thr Ala Ala Leu Ala Val Ala Ile Ala Asn Val Tyr Gly Glu 230 235 240 245 aag ccg gtt gat tca gct tta tct gtc atc gcg atg ggc aaa tgt ggc 883 Lys Pro Val Asp Ser Ala Leu Ser Val Ile Ala Met Gly Lys Cys Gly 250 255 260 gcg cag gaa ttg aac tac att tca gat gtg gac gtg gtg ttt gtt gca 931 Ala Gln Glu Leu Asn Tyr Ile Ser Asp Val Asp Val Val Phe Val Ala 265 270 275 gag ccg gca aac tct aaa tca aca cgc acc gca gca gag ctc att cgc 979 Glu Pro Ala Asn Ser Lys Ser Thr Arg Thr Ala Ala Glu Leu Ile Arg 280 285 290 atc ggt agc aac tcg ttc ttt gag gtg gat gca gca ctt cgc cca gaa 1027 Ile Gly Ser Asn Ser Phe Phe Glu Val Asp Ala Ala Leu Arg Pro Glu 295 300 305 ggt aaa agt ggc gct ctt gtg cgc tct ttg gat tcc cat atg gcg tat 1075 Gly Lys Ser Gly Ala Leu Val Arg Ser Leu Asp Ser His Met Ala Tyr 310 315 320 325 tac aag cgc tgg gcg gaa acc tgg gag ttt cag gca ctg ctg aaa gct 1123 Tyr Lys Arg Trp Ala Glu Thr Trp Glu Phe Gln Ala Leu Leu Lys Ala 330 335 340 cgt ccc atg acg ggt gat att aac ctt ggg cag tcc tat gtg gat gct 1171 Arg Pro Met Thr Gly Asp Ile Asn Leu Gly Gln Ser Tyr Val Asp Ala 345 350 355 ctt tca ccg ttg att tgg acg gct agc cag cgg gaa tca ttt gtc aca 1219 Leu Ser Pro Leu Ile Trp Thr Ala Ser Gln Arg Glu Ser Phe Val Thr 360 365 370 gat gtc caa gct atg cgc cgt cga gtg ttg gac aat gtt ccg gaa gac 1267 Asp Val Gln Ala Met Arg Arg Arg Val Leu Asp Asn Val Pro Glu Asp 375 380 385 ttg cgt gat cgt gag ctg aag ctt ggt cgc ggt ggt ttg agg gat gtg 1315 Leu Arg Asp Arg Glu Leu Lys Leu Gly Arg Gly Gly Leu Arg Asp Val 390 395 400 405 gag ttt gct gtc cag ctc ctt cag atg gtg cat ggt cgc att gat gag 1363 Glu Phe Ala Val Gln Leu Leu Gln Met Val His Gly Arg Ile Asp Glu 410 415 420 acg ttg cgg gtt cgg tca acg gta aat gct ttg cat gtg ttg gtt gat 1411 Thr Leu Arg Val Arg Ser Thr Val Asn Ala Leu His Val Leu Val Asp 425 430 435 cag gga tat gtg ggt cgt gaa gac ggg cat aat ctc att gag tcg tat 1459 Gln Gly Tyr Val Gly Arg Glu Asp Gly His Asn Leu Ile Glu Ser Tyr 440 445 450 gag ttt ttg cgt ctg ttg gag cat cgc ctt caa ttg gag cgg atc aag 1507 Glu Phe Leu Arg Leu Leu Glu His Arg Leu Gln Leu Glu Arg Ile Lys 455 460 465 cgc act cac ttg tta ccg aaa cct gat gac cga atg aat atg cgc tgg 1555 Arg Thr His Leu Leu Pro Lys Pro Asp Asp Arg Met Asn Met Arg Trp 470 475 480 485 ttg gcg cgc gct tct ggg ttt act ggt tcg atg gag caa agt tcg gcc 1603 Leu Ala Arg Ala Ser Gly Phe Thr Gly Ser Met Glu Gln Ser Ser Ala 490 495 500 aaa gct atg gaa cgg cat ttg cgt aag gtt cgt ttg cag att cag tcg 1651 Lys Ala Met Glu Arg His Leu Arg Lys Val Arg Leu Gln Ile Gln Ser 505 510 515 ttg cat agt cag ctg ttt tat cgg cca ctg ctg aac tct gtg gtc aac 1699 Leu His Ser Gln Leu Phe Tyr Arg Pro Leu Leu Asn Ser Val Val Asn 520 525 530 ttg agc gcg gat gcc atc agg ttg tct ccg gat gct gca aag cta caa 1747 Leu Ser Ala Asp Ala Ile Arg Leu Ser Pro Asp Ala Ala Lys Leu Gln 535 540 545 ttg gcg gca ttg gga tac ctg cat cca tca cgt gct tat gaa cac ctg 1795 Leu Ala Ala Leu Gly Tyr Leu His Pro Ser Arg Ala Tyr Glu His Leu 550 555 560 565 act gct ctt gca tca gga gct agc cgt aaa gcc aag att cag gcg atg 1843 Thr Ala Leu Ala Ser Gly Ala Ser Arg Lys Ala Lys Ile Gln Ala Met 570 575 580 ttg ctg ccc acg ttg atg gag tgg ctg tct caa aca gct gaa cca gat 1891 Leu Leu Pro Thr Leu Met Glu Trp Leu Ser Gln Thr Ala Glu Pro Asp 585 590 595 gcg gga ttg ctg aat tac cgc aag ctt tct gat gct tcc tat gat cgc 1939 Ala Gly Leu Leu Asn Tyr Arg Lys Leu Ser Asp Ala Ser Tyr Asp Arg 600 605 610 agc tgg ttt ttg cgc atg ctg cgt gat gag ggc gta gtg ggg cag cgg 1987 Ser Trp Phe Leu Arg Met Leu Arg Asp Glu Gly Val Val Gly Gln Arg 615 620 625 ttg atg cgt att ttg gga aat tct ccc tat att tct gaa ctg att atc 2035 Leu Met Arg Ile Leu Gly Asn Ser Pro Tyr Ile Ser Glu Leu Ile Ile 630 635 640 645 tcc act ccg gac ttt atg aaa cag ctg ggt gat gcg gcg tct ggt cct 2083 Ser Thr Pro Asp Phe Met Lys Gln Leu Gly Asp Ala Ala Ser Gly Pro 650 655 660 aaa ttg ctt gct act gca ccg act cag gtt gtg aaa gca atc aag gca 2131 Lys Leu Leu Ala Thr Ala Pro Thr Gln Val Val Lys Ala Ile Lys Ala 665 670 675 acg gtg tcg cgt cat gag tca cct gat cgg gcg atc cag gct gca cga 2179 Thr Val Ser Arg His Glu Ser Pro Asp Arg Ala Ile Gln Ala Ala Arg 680 685 690 tcg ctg agg agg cag gag ctg gca cgc att gcc tct gct gat ttg ctc 2227 Ser Leu Arg Arg Gln Glu Leu Ala Arg Ile Ala Ser Ala Asp Leu Leu 695 700 705 aac atg ctc act gtt cag gaa gta tgc caa agc ttg tca cta gtc tgg 2275 Asn Met Leu Thr Val Gln Glu Val Cys Gln Ser Leu Ser Leu Val Trp 710 715 720 725 gat gcg gtg ttg gat gct gcc ttg gat gcg gaa atc cgt gct gca ctt 2323 Asp Ala Val Leu Asp Ala Ala Leu Asp Ala Glu Ile Arg Ala Ala Leu 730 735 740 aac gat cca cag aaa cca gat cag cct ctg gcc aat att tct gtg atc 2371 Asn Asp Pro Gln Lys Pro Asp Gln Pro Leu Ala Asn Ile Ser Val Ile 745 750 755 ggc atg ggc cgt ttg ggt gga gca gaa ctt gga tac ggt tct gat gcc 2419 Gly Met Gly Arg Leu Gly Gly Ala Glu Leu Gly Tyr Gly Ser Asp Ala 760 765 770 gat gtg atg ttt gta tgc gag ccg gta gcc ggt gtg gaa gag cat gag 2467 Asp Val Met Phe Val Cys Glu Pro Val Ala Gly Val Glu Glu His Glu 775 780 785 gcc gtc aca tgg tct att gct atc tgt gat tcc atg cgg tcg agg ctt 2515 Ala Val Thr Trp Ser Ile Ala Ile Cys Asp Ser Met Arg Ser Arg Leu 790 795 800 805 gcg cag cct tcc ggt gat cca cct ttg gag gtg gat ctg ggg ctg cgt 2563 Ala Gln Pro Ser Gly Asp Pro Pro Leu Glu Val Asp Leu Gly Leu Arg 810 815 820 cct gaa ggg aga tct ggt gcg att gtg cgc acc gtt gat tcc tat gtg 2611 Pro Glu Gly Arg Ser Gly Ala Ile Val Arg Thr Val Asp Ser Tyr Val 825 830 835 aag tac tac gaa aag tgg ggt gaa act tgg gag att cag gcg ctg ctg 2659 Lys Tyr Tyr Glu Lys Trp Gly Glu Thr Trp Glu Ile Gln Ala Leu Leu 840 845 850 agg gct gcg tgg gtt gct ggt gat cgt gag ctg ggt att aag ttc ttg 2707 Arg Ala Ala Trp Val Ala Gly Asp Arg Glu Leu Gly Ile Lys Phe Leu 855 860 865 gag tcg att gat cgt ttc cgc tac cca gtt gac ggg gca acg cag gcg 2755 Glu Ser Ile Asp Arg Phe Arg Tyr Pro Val Asp Gly Ala Thr Gln Ala 870 875 880 885 cag ctt cgt gaa gtt cgt cga att aag gcg agg gtg gat aat gag agg 2803 Gln Leu Arg Glu Val Arg Arg Ile Lys Ala Arg Val Asp Asn Glu Arg 890 895 900 ctt ccg cgc ggg gct gat cga aat acc cat acc aag ctg ggt cgg gga 2851 Leu Pro Arg Gly Ala Asp Arg Asn Thr His Thr Lys Leu Gly Arg Gly 905 910 915 gcg tta act gac atc gag tgg act gtg cag ttg ttg acc atg atg cat 2899 Ala Leu Thr Asp Ile Glu Trp Thr Val Gln Leu Leu Thr Met Met His 920 925 930 gct cat gag att ccg gag ctg cac aat acg tcg acg ttg gaa gtt ctt 2947 Ala His Glu Ile Pro Glu Leu His Asn Thr Ser Thr Leu Glu Val Leu 935 940 945 gaa gtg ctg gaa aag cat cag att att aac cct gtg cag gtg cag acg 2995 Glu Val Leu Glu Lys His Gln Ile Ile Asn Pro Val Gln Val Gln Thr 950 955 960 965 ctt cgg gaa gcg tgg ctg acg gca acg gct gct agg aat gcg ctt gtg 3043 Leu Arg Glu Ala Trp Leu Thr Ala Thr Ala Ala Arg Asn Ala Leu Val 970 975 980 ctg gtc agg ggt aag aga tta gat cag tta cct act cct ggt ccg cac 3091 Leu Val Arg Gly Lys Arg Leu Asp Gln Leu Pro Thr Pro Gly Pro His 985 990 995 ctt gcg cag gtg gct ggt gcg tct ggt tgg gat cca aat gag tac cag 3139 Leu Ala Gln Val Ala Gly Ala Ser Gly Trp Asp Pro Asn Glu Tyr Gln 1000 1005 1010 gag tat ttg gaa aac tat ctg aaa gtg acc agg aag agt cgt cag gtt 3187 Glu Tyr Leu Glu Asn Tyr Leu Lys Val Thr Arg Lys Ser Arg Gln Val 1015 1020 1025 gtt gat gaa gtc ttc tgg ggt gtg gac tct atg gag caa cgt gag ttt 3235 Val Asp Glu Val Phe Trp Gly Val Asp Ser Met Glu Gln Arg Glu Phe 1030 1035 1040 1045 taggtaggtg gtgggagccc caa 3258 <210> 100 <211> 1045 <212> PRT <213> Corynebacterium glutamicum <400> 100 Met Ser Gly Pro Leu Arg Ser Glu Arg Lys Val Val Gly Phe Val Arg 1 5 10 15 Asp Pro Leu Pro Lys Val Gly Ser Leu Ser Leu Lys Ser Glu His Ala 20 25 30 Gln Ala Asp Leu Glu His Leu Gly Trp Arg Asn Val Glu Ser Leu Asp 35 40 45 Leu Leu Trp Gly Leu Ser Gly Ala Gly Asp Pro Asp Val Ala Leu Asn 50 55 60 Leu Leu Ile Arg Leu Tyr Gln Ala Leu Glu Ala Ile Gly Glu Asp Ala 65 70 75 80 Arg Asn Glu Leu Asp Gln Glu Ile Arg Gln Asp Glu Lys Leu Arg Val 85 90 95 Arg Leu Phe Ala Leu Leu Gly Gly Ser Ser Ala Val Gly Asp His Leu 100 105 110 Val Ala Asn Pro Leu Gln Trp Lys Leu Leu Lys Leu Asp Ala Pro Ser 115 120 125 Arg Glu Glu Met Phe Gln Ala Leu Leu Glu Ser Val Lys Ala Gln Pro 130 135 140 Ala Val Leu Glu Val Glu Asp Phe Ser Asp Ala His Asn Ile Ala Arg 145 150 155 160 Asp Asp Leu Ser Thr Pro Gly Phe Tyr Thr Ala Ser Val Thr Gly Pro 165 170 175 Glu Ala Glu Arg Val Leu Lys Trp Thr Tyr Arg Thr Leu Leu Thr Arg 180 185 190 Ile Ala Ala His Asp Leu Ala Gly Thr Tyr Pro Thr Asp Met Arg Arg 195 200 205 Lys Gly Gly Asp Pro Val Pro Phe Ser Thr Val Thr Met Gln Leu Ser 210 215 220 Asp Leu Ala Asp Ala Ala Leu Thr Ala Ala Leu Ala Val Ala Ile Ala 225 230 235 240 Asn Val Tyr Gly Glu Lys Pro Val Asp Ser Ala Leu Ser Val Ile Ala 245 250 255 Met Gly Lys Cys Gly Ala Gln Glu Leu Asn Tyr Ile Ser Asp Val Asp 260 265 270 Val Val Phe Val Ala Glu Pro Ala Asn Ser Lys Ser Thr Arg Thr Ala 275 280 285 Ala Glu Leu Ile Arg Ile Gly Ser Asn Ser Phe Phe Glu Val Asp Ala 290 295 300 Ala Leu Arg Pro Glu Gly Lys Ser Gly Ala Leu Val Arg Ser Leu Asp 305 310 315 320 Ser His Met Ala Tyr Tyr Lys Arg Trp Ala Glu Thr Trp Glu Phe Gln 325 330 335 Ala Leu Leu Lys Ala Arg Pro Met Thr Gly Asp Ile Asn Leu Gly Gln 340 345 350 Ser Tyr Val Asp Ala Leu Ser Pro Leu Ile Trp Thr Ala Ser Gln Arg 355 360 365 Glu Ser Phe Val Thr Asp Val Gln Ala Met Arg Arg Arg Val Leu Asp 370 375 380 Asn Val Pro Glu Asp Leu Arg Asp Arg Glu Leu Lys Leu Gly Arg Gly 385 390 395 400 Gly Leu Arg Asp Val Glu Phe Ala Val Gln Leu Leu Gln Met Val His 405 410 415 Gly Arg Ile Asp Glu Thr Leu Arg Val Arg Ser Thr Val Asn Ala Leu 420 425 430 His Val Leu Val Asp Gln Gly Tyr Val Gly Arg Glu Asp Gly His Asn 435 440 445 Leu Ile Glu Ser Tyr Glu Phe Leu Arg Leu Leu Glu His Arg Leu Gln 450 455 460 Leu Glu Arg Ile Lys Arg Thr His Leu Leu Pro Lys Pro Asp Asp Arg 465 470 475 480 Met Asn Met Arg Trp Leu Ala Arg Ala Ser Gly Phe Thr Gly Ser Met 485 490 495 Glu Gln Ser Ser Ala Lys Ala Met Glu Arg His Leu Arg Lys Val Arg 500 505 510 Leu Gln Ile Gln Ser Leu His Ser Gln Leu Phe Tyr Arg Pro Leu Leu 515 520 525 Asn Ser Val Val Asn Leu Ser Ala Asp Ala Ile Arg Leu Ser Pro Asp 530 535 540 Ala Ala Lys Leu Gln Leu Ala Ala Leu Gly Tyr Leu His Pro Ser Arg 545 550 555 560 Ala Tyr Glu His Leu Thr Ala Leu Ala Ser Gly Ala Ser Arg Lys Ala 565 570 575 Lys Ile Gln Ala Met Leu Leu Pro Thr Leu Met Glu Trp Leu Ser Gln 580 585 590 Thr Ala Glu Pro Asp Ala Gly Leu Leu Asn Tyr Arg Lys Leu Ser Asp 595 600 605 Ala Ser Tyr Asp Arg Ser Trp Phe Leu Arg Met Leu Arg Asp Glu Gly 610 615 620 Val Val Gly Gln Arg Leu Met Arg Ile Leu Gly Asn Ser Pro Tyr Ile 625 630 635 640 Ser Glu Leu Ile Ile Ser Thr Pro Asp Phe Met Lys Gln Leu Gly Asp 645 650 655 Ala Ala Ser Gly Pro Lys Leu Leu Ala Thr Ala Pro Thr Gln Val Val 660 665 670 Lys Ala Ile Lys Ala Thr Val Ser Arg His Glu Ser Pro Asp Arg Ala 675 680 685 Ile Gln Ala Ala Arg Ser Leu Arg Arg Gln Glu Leu Ala Arg Ile Ala 690 695 700 Ser Ala Asp Leu Leu Asn Met Leu Thr Val Gln Glu Val Cys Gln Ser 705 710 715 720 Leu Ser Leu Val Trp Asp Ala Val Leu Asp Ala Ala Leu Asp Ala Glu 725 730 735 Ile Arg Ala Ala Leu Asn Asp Pro Gln Lys Pro Asp Gln Pro Leu Ala 740 745 750 Asn Ile Ser Val Ile Gly Met Gly Arg Leu Gly Gly Ala Glu Leu Gly 755 760 765 Tyr Gly Ser Asp Ala Asp Val Met Phe Val Cys Glu Pro Val Ala Gly 770 775 780 Val Glu Glu His Glu Ala Val Thr Trp Ser Ile Ala Ile Cys Asp Ser 785 790 795 800 Met Arg Ser Arg Leu Ala Gln Pro Ser Gly Asp Pro Pro Leu Glu Val 805 810 815 Asp Leu Gly Leu Arg Pro Glu Gly Arg Ser Gly Ala Ile Val Arg Thr 820 825 830 Val Asp Ser Tyr Val Lys Tyr Tyr Glu Lys Trp Gly Glu Thr Trp Glu 835 840 845 Ile Gln Ala Leu Leu Arg Ala Ala Trp Val Ala Gly Asp Arg Glu Leu 850 855 860 Gly Ile Lys Phe Leu Glu Ser Ile Asp Arg Phe Arg Tyr Pro Val Asp 865 870 875 880 Gly Ala Thr Gln Ala Gln Leu Arg Glu Val Arg Arg Ile Lys Ala Arg 885 890 895 Val Asp Asn Glu Arg Leu Pro Arg Gly Ala Asp Arg Asn Thr His Thr 900 905 910 Lys Leu Gly Arg Gly Ala Leu Thr Asp Ile Glu Trp Thr Val Gln Leu 915 920 925 Leu Thr Met Met His Ala His Glu Ile Pro Glu Leu His Asn Thr Ser 930 935 940 Thr Leu Glu Val Leu Glu Val Leu Glu Lys His Gln Ile Ile Asn Pro 945 950 955 960 Val Gln Val Gln Thr Leu Arg Glu Ala Trp Leu Thr Ala Thr Ala Ala 965 970 975 Arg Asn Ala Leu Val Leu Val Arg Gly Lys Arg Leu Asp Gln Leu Pro 980 985 990 Thr Pro Gly Pro His Leu Ala Gln Val Ala Gly Ala Ser Gly Trp Asp 995 1000 1005 Pro Asn Glu Tyr Gln Glu Tyr Leu Glu Asn Tyr Leu Lys Val Thr Arg 1010 1015 1020 Lys Ser Arg Gln Val Val Asp Glu Val Phe Trp Gly Val Asp Ser Met 1025 1030 1035 1040 Glu Gln Arg Glu Phe 1045 <210> 101 <211> 861 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(861) <223> RXN03176 <400> 101 gag ttg gcc gat tac atc ccg gaa cta aaa tct gcg gac cca aac ccg 48 Glu Leu Ala Asp Tyr Ile Pro Glu Leu Lys Ser Ala Asp Pro Asn Pro 1 5 10 15 ctg gca gta gcc ctg tgc acc gtt aac gga cac atc tac agc gca ggc 96 Leu Ala Val Ala Leu Cys Thr Val Asn Gly His Ile Tyr Ser Ala Gly 20 25 30 gat gac gac atc gaa ttc acc atg caa agt att tcc aag cca ttt gcc 144 Asp Asp Asp Ile Glu Phe Thr Met Gln Ser Ile Ser Lys Pro Phe Ala 35 40 45 tac gca ctc gca ctc caa gaa tgc ggc ttt gat gag gtc tct gca tcc 192 Tyr Ala Leu Ala Leu Gln Glu Cys Gly Phe Asp Glu Val Ser Ala Ser 50 55 60 gtg gcc ttg gag ccc tcc ggt gag gcc ttc aac gaa ctt tcc ctc gac 240 Val Ala Leu Glu Pro Ser Gly Glu Ala Phe Asn Glu Leu Ser Leu Asp 65 70 75 80 ggc gaa aac cgc ccc atg aac ccc atg atc aac gcc ggc gcg atc gcc 288 Gly Glu Asn Arg Pro Met Asn Pro Met Ile Asn Ala Gly Ala Ile Ala 85 90 95 atc aac cag ctg atc aac ggc tcc gat tcc acc gtg gaa gac cgc gtg 336 Ile Asn Gln Leu Ile Asn Gly Ser Asp Ser Thr Val Glu Asp Arg Val 100 105 110 gaa aaa atc cga cac tac ttc tct gaa ctt gct gga cgc gaa ctc acc 384 Glu Lys Ile Arg His Tyr Phe Ser Glu Leu Ala Gly Arg Glu Leu Thr 115 120 125 atc gac cgc gtg ctt gcc gaa tcc gaa ctc gcc ggc gcc gac cgc aac 432 Ile Asp Arg Val Leu Ala Glu Ser Glu Leu Ala Gly Ala Asp Arg Asn 130 135 140 ctc tcc atc gcc cac atg ctg cgc aat tac ggc gtc atc gaa gac gaa 480 Leu Ser Ile Ala His Met Leu Arg Asn Tyr Gly Val Ile Glu Asp Glu 145 150 155 160 gcc cac gac gcc gtc ctc agc tac acg ctg caa tgc gcc atc aaa gta 528 Ala His Asp Ala Val Leu Ser Tyr Thr Leu Gln Cys Ala Ile Lys Val 165 170 175 acc acg cgc gac ctc gca gtc atg acc gcc acg ctc gcc gcc ggc ggc 576 Thr Thr Arg Asp Leu Ala Val Met Thr Ala Thr Leu Ala Ala Gly Gly 180 185 190 aca cac cca att acc ggc aag aag ctt ctc gac gcc cgc gtc tgc cgc 624 Thr His Pro Ile Thr Gly Lys Lys Leu Leu Asp Ala Arg Val Cys Arg 195 200 205 ctc acc ctc tcc gtc atg gct tca gca ggc atg tac gac gag gca ggg 672 Leu Thr Leu Ser Val Met Ala Ser Ala Gly Met Tyr Asp Glu Ala Gly 210 215 220 cag tgg ctc tcc acc gta ggc atc ccc gcg aaa tca gga gtc gcc ggc 720 Gln Trp Leu Ser Thr Val Gly Ile Pro Ala Lys Ser Gly Val Ala Gly 225 230 235 240 gga ctc atc ggc att ctg cca ggt cag ctg ggc atc gcc aca ttt tcc 768 Gly Leu Ile Gly Ile Leu Pro Gly Gln Leu Gly Ile Ala Thr Phe Ser 245 250 255 cca cgc ctg aac ccc aaa ggc aac agc gtg cgc ggc gta aaa ata ttc 816 Pro Arg Leu Asn Pro Lys Gly Asn Ser Val Arg Gly Val Lys Ile Phe 260 265 270 aaa cag ctt tcc gac gac atg ggc ctc cac ctc atg tcc acc gag 861 Lys Gln Leu Ser Asp Asp Met Gly Leu His Leu Met Ser Thr Glu 275 280 285 <210> 102 <211> 287 <212> PRT <213> Corynebacterium glutamicum <400> 102 Glu Leu Ala Asp Tyr Ile Pro Glu Leu Lys Ser Ala Asp Pro Asn Pro 1 5 10 15 Leu Ala Val Ala Leu Cys Thr Val Asn Gly His Ile Tyr Ser Ala Gly 20 25 30 Asp Asp Asp Ile Glu Phe Thr Met Gln Ser Ile Ser Lys Pro Phe Ala 35 40 45 Tyr Ala Leu Ala Leu Gln Glu Cys Gly Phe Asp Glu Val Ser Ala Ser 50 55 60 Val Ala Leu Glu Pro Ser Gly Glu Ala Phe Asn Glu Leu Ser Leu Asp 65 70 75 80 Gly Glu Asn Arg Pro Met Asn Pro Met Ile Asn Ala Gly Ala Ile Ala 85 90 95 Ile Asn Gln Leu Ile Asn Gly Ser Asp Ser Thr Val Glu Asp Arg Val 100 105 110 Glu Lys Ile Arg His Tyr Phe Ser Glu Leu Ala Gly Arg Glu Leu Thr 115 120 125 Ile Asp Arg Val Leu Ala Glu Ser Glu Leu Ala Gly Ala Asp Arg Asn 130 135 140 Leu Ser Ile Ala His Met Leu Arg Asn Tyr Gly Val Ile Glu Asp Glu 145 150 155 160 Ala His Asp Ala Val Leu Ser Tyr Thr Leu Gln Cys Ala Ile Lys Val 165 170 175 Thr Thr Arg Asp Leu Ala Val Met Thr Ala Thr Leu Ala Ala Gly Gly 180 185 190 Thr His Pro Ile Thr Gly Lys Lys Leu Leu Asp Ala Arg Val Cys Arg 195 200 205 Leu Thr Leu Ser Val Met Ala Ser Ala Gly Met Tyr Asp Glu Ala Gly 210 215 220 Gln Trp Leu Ser Thr Val Gly Ile Pro Ala Lys Ser Gly Val Ala Gly 225 230 235 240 Gly Leu Ile Gly Ile Leu Pro Gly Gln Leu Gly Ile Ala Thr Phe Ser 245 250 255 Pro Arg Leu Asn Pro Lys Gly Asn Ser Val Arg Gly Val Lys Ile Phe 260 265 270 Lys Gln Leu Ser Asp Asp Met Gly Leu His Leu Met Ser Thr Glu 275 280 285 <210> 103 <211> 861 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(861) <223> FRXA02879 <400> 103 gag ttg gcc gat tac atc ccg gaa cta aaa tct gcg gac cca aac ccg 48 Glu Leu Ala Asp Tyr Ile Pro Glu Leu Lys Ser Ala Asp Pro Asn Pro 1 5 10 15 ctg gca gta gcc ctg tgc acc gtt aac gga cac atc tac agc gca ggc 96 Leu Ala Val Ala Leu Cys Thr Val Asn Gly His Ile Tyr Ser Ala Gly 20 25 30 gat gac gac atc gaa ttc acc atg caa agt att tcc aag cca ttt gcc 144 Asp Asp Asp Ile Glu Phe Thr Met Gln Ser Ile Ser Lys Pro Phe Ala 35 40 45 tac gca ctc gca ctc caa gaa tgc ggc ttt gat gag gtc tct gca tcc 192 Tyr Ala Leu Ala Leu Gln Glu Cys Gly Phe Asp Glu Val Ser Ala Ser 50 55 60 gtg gcc ttg gag ccc tcc ggt gag gcc ttc aac gaa ctt tcc ctc gac 240 Val Ala Leu Glu Pro Ser Gly Glu Ala Phe Asn Glu Leu Ser Leu Asp 65 70 75 80 ggc gaa aac cgc ccc atg aac ccc atg atc aac gcc ggc gcg atc gcc 288 Gly Glu Asn Arg Pro Met Asn Pro Met Ile Asn Ala Gly Ala Ile Ala 85 90 95 atc aac cag ctg atc aac ggc tcc gat tcc acc gtg gaa gac cgc gtg 336 Ile Asn Gln Leu Ile Asn Gly Ser Asp Ser Thr Val Glu Asp Arg Val 100 105 110 gaa aaa atc cga cac tac ttc tct gaa ctt gct gga cgc gaa ctc acc 384 Glu Lys Ile Arg His Tyr Phe Ser Glu Leu Ala Gly Arg Glu Leu Thr 115 120 125 atc gac cgc gtg ctt gcc gaa tcc gaa ctc gcc ggc gcc gac cgc aac 432 Ile Asp Arg Val Leu Ala Glu Ser Glu Leu Ala Gly Ala Asp Arg Asn 130 135 140 ctc tcc atc gcc cac atg ctg cgc aat tac ggc gtc atc gaa gac gaa 480 Leu Ser Ile Ala His Met Leu Arg Asn Tyr Gly Val Ile Glu Asp Glu 145 150 155 160 gcc cac gac gcc gtc ctc agc tac acg ctg caa tgc gcc atc aaa gta 528 Ala His Asp Ala Val Leu Ser Tyr Thr Leu Gln Cys Ala Ile Lys Val 165 170 175 acc acg cgc gac ctc gca gtc atg acc gcc acg ctc gcc gcc ggc ggc 576 Thr Thr Arg Asp Leu Ala Val Met Thr Ala Thr Leu Ala Ala Gly Gly 180 185 190 aca cac cca att acc ggc aag aag ctt ctc gac gcc cgc gtc tgc cgc 624 Thr His Pro Ile Thr Gly Lys Lys Leu Leu Asp Ala Arg Val Cys Arg 195 200 205 ctc acc ctc tcc gtc atg gct tca gca ggc atg tac gac gag gca ggg 672 Leu Thr Leu Ser Val Met Ala Ser Ala Gly Met Tyr Asp Glu Ala Gly 210 215 220 cag tgg ctc tcc acc gta ggc atc ccc gcg aaa tca gga gtc gcc ggc 720 Gln Trp Leu Ser Thr Val Gly Ile Pro Ala Lys Ser Gly Val Ala Gly 225 230 235 240 gga ctc atc ggc att ctg cca ggt cag ctg ggc atc gcc aca ttt tcc 768 Gly Leu Ile Gly Ile Leu Pro Gly Gln Leu Gly Ile Ala Thr Phe Ser 245 250 255 cca cgc ctg aac ccc aaa ggc aac agc gtg cgc ggc gta aaa ata ttc 816 Pro Arg Leu Asn Pro Lys Gly Asn Ser Val Arg Gly Val Lys Ile Phe 260 265 270 aaa cag ctt tcc gac gac atg ggc ctc cac ctc atg tcc acc gag 861 Lys Gln Leu Ser Asp Asp Met Gly Leu His Leu Met Ser Thr Glu 275 280 285 <210> 104 <211> 287 <212> PRT <213> Corynebacterium glutamicum <400> 104 Glu Leu Ala Asp Tyr Ile Pro Glu Leu Lys Ser Ala Asp Pro Asn Pro 1 5 10 15 Leu Ala Val Ala Leu Cys Thr Val Asn Gly His Ile Tyr Ser Ala Gly 20 25 30 Asp Asp Asp Ile Glu Phe Thr Met Gln Ser Ile Ser Lys Pro Phe Ala 35 40 45 Tyr Ala Leu Ala Leu Gln Glu Cys Gly Phe Asp Glu Val Ser Ala Ser 50 55 60 Val Ala Leu Glu Pro Ser Gly Glu Ala Phe Asn Glu Leu Ser Leu Asp 65 70 75 80 Gly Glu Asn Arg Pro Met Asn Pro Met Ile Asn Ala Gly Ala Ile Ala 85 90 95 Ile Asn Gln Leu Ile Asn Gly Ser Asp Ser Thr Val Glu Asp Arg Val 100 105 110 Glu Lys Ile Arg His Tyr Phe Ser Glu Leu Ala Gly Arg Glu Leu Thr 115 120 125 Ile Asp Arg Val Leu Ala Glu Ser Glu Leu Ala Gly Ala Asp Arg Asn 130 135 140 Leu Ser Ile Ala His Met Leu Arg Asn Tyr Gly Val Ile Glu Asp Glu 145 150 155 160 Ala His Asp Ala Val Leu Ser Tyr Thr Leu Gln Cys Ala Ile Lys Val 165 170 175 Thr Thr Arg Asp Leu Ala Val Met Thr Ala Thr Leu Ala Ala Gly Gly 180 185 190 Thr His Pro Ile Thr Gly Lys Lys Leu Leu Asp Ala Arg Val Cys Arg 195 200 205 Leu Thr Leu Ser Val Met Ala Ser Ala Gly Met Tyr Asp Glu Ala Gly 210 215 220 Gln Trp Leu Ser Thr Val Gly Ile Pro Ala Lys Ser Gly Val Ala Gly 225 230 235 240 Gly Leu Ile Gly Ile Leu Pro Gly Gln Leu Gly Ile Ala Thr Phe Ser 245 250 255 Pro Arg Leu Asn Pro Lys Gly Asn Ser Val Arg Gly Val Lys Ile Phe 260 265 270 Lys Gln Leu Ser Asp Asp Met Gly Leu His Leu Met Ser Thr Glu 275 280 285 <210> 105 <211> 1155 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1132) <223> RXA00278 <400> 105 ggccacggag ttggtgtccg tcatggtgat gattctgtct gtcgtttctg tgttggcttt 60 gtgggtcggc atccgccccc gtttgcagga gtacttataa atg cac gct ttt cga 115 Met His Ala Phe Arg 1 5 cgc ccc cct cca ctc acc acg cga gtc ggc gct gca ttg ctg gcc gca 163 Arg Pro Pro Pro Leu Thr Thr Arg Val Gly Ala Ala Leu Leu Ala Ala 10 15 20 acg ctg ctt gct tcc tgc act cca aca cct gtg gaa ccg gca gaa acc 211 Thr Leu Leu Ala Ser Cys Thr Pro Thr Pro Val Glu Pro Ala Glu Thr 25 30 35 ttg act gct ttg gat ccc gat gcc ggt cca cca ctg cca ccg gat tct 259 Leu Thr Ala Leu Asp Pro Asp Ala Gly Pro Pro Leu Pro Pro Asp Ser 40 45 50 tcg att gaa gct ccc ggt gaa aaa gag ccc att gtg gaa gta ata gag 307 Ser Ile Glu Ala Pro Gly Glu Lys Glu Pro Ile Val Glu Val Ile Glu 55 60 65 aat tgg cca ggt tct tta cgc ccg gat gat ctg acc cct gag gag cgg 355 Asn Trp Pro Gly Ser Leu Arg Pro Asp Asp Leu Thr Pro Glu Glu Arg 70 75 80 85 gta cct ggc atc gtc aac cgg ggt cgc atc att gtg ggt gtg gat caa 403 Val Pro Gly Ile Val Asn Arg Gly Arg Ile Ile Val Gly Val Asp Gln 90 95 100 tcg caa aac ttg ctc agt ttc cgt gat ccg gtg act ggt gag ctg cgc 451 Ser Gln Asn Leu Leu Ser Phe Arg Asp Pro Val Thr Gly Glu Leu Arg 105 110 115 ggt ttt gaa gtg gaa tta gcg agg gaa att tcc cgc gac att ttc ggt 499 Gly Phe Glu Val Glu Leu Ala Arg Glu Ile Ser Arg Asp Ile Phe Gly 120 125 130 gac ccc aat aag gtg gat ttc cga ttc gtc ggc tcg tcc gac cgt ctg 547 Asp Pro Asn Lys Val Asp Phe Arg Phe Val Gly Ser Ser Asp Arg Leu 135 140 145 cgt tcc ctt gac caa ggt gat gta gat att gtg att cgt tcc gtc acg 595 Arg Ser Leu Asp Gln Gly Asp Val Asp Ile Val Ile Arg Ser Val Thr 150 155 160 165 atc acc gac gaa cgc gcc aaa ttg gtg gaa ttt tcc aca ccg tac ctg 643 Ile Thr Asp Glu Arg Ala Lys Leu Val Glu Phe Ser Thr Pro Tyr Leu 170 175 180 cgc acc caa acc cgc atg ttg acc atg gaa tct tca gga atc acg tcc 691 Arg Thr Gln Thr Arg Met Leu Thr Met Glu Ser Ser Gly Ile Thr Ser 185 190 195 atc gca gat cta ccc ggc cac acc att tgt gtc acc gat ggc tcc act 739 Ile Ala Asp Leu Pro Gly His Thr Ile Cys Val Thr Asp Gly Ser Thr 200 205 210 tca ttg cag cga gcc cgc acc att gcg ccg gag gcc tca atc tta aaa 787 Ser Leu Gln Arg Ala Arg Thr Ile Ala Pro Glu Ala Ser Ile Leu Lys 215 220 225 act cgc aat tgg tcc gat tgt ctc atg gcg ttg cag cag cat cag gct 835 Thr Arg Asn Trp Ser Asp Cys Leu Met Ala Leu Gln Gln His Gln Ala 230 235 240 245 cag gtc att ttg ggc gat gat gtc att ttg tcc ggc atc gca gca cag 883 Gln Val Ile Leu Gly Asp Asp Val Ile Leu Ser Gly Ile Ala Ala Gln 250 255 260 gat ccc tac acc gag att ctt gat acc tcc ctc gat tcc cat tcc tat 931 Asp Pro Tyr Thr Glu Ile Leu Asp Thr Ser Leu Asp Ser His Ser Tyr 265 270 275 gga gtg gca gcg gca tcg acc act gct gaa aca gac tct tcg ggg ttg 979 Gly Val Ala Ala Ala Ser Thr Thr Ala Glu Thr Asp Ser Ser Gly Leu 280 285 290 att cgg cag gta aac tac aca att gaa cgg atc cgc aca gac cgc atg 1027 Ile Arg Gln Val Asn Tyr Thr Ile Glu Arg Ile Arg Thr Asp Arg Met 295 300 305 tgg tgg aca atg ttc gac gat tgg ttc gga cct tat ctc tgg tcc tac 1075 Trp Trp Thr Met Phe Asp Asp Trp Phe Gly Pro Tyr Leu Trp Ser Tyr 310 315 320 325 ggt cca cca cag ctg cag tac atg cca gag gaa gaa ggg aca gaa aac 1123 Gly Pro Pro Gln Leu Gln Tyr Met Pro Glu Glu Glu Gly Thr Glu Asn 330 335 340 gat gaa gga taatgaagat ttcgatccag att 1155 Asp Glu Gly <210> 106 <211> 344 <212> PRT <213> Corynebacterium glutamicum <400> 106 Met His Ala Phe Arg Arg Pro Pro Pro Leu Thr Thr Arg Val Gly Ala 1 5 10 15 Ala Leu Leu Ala Ala Thr Leu Leu Ala Ser Cys Thr Pro Thr Pro Val 20 25 30 Glu Pro Ala Glu Thr Leu Thr Ala Leu Asp Pro Asp Ala Gly Pro Pro 35 40 45 Leu Pro Pro Asp Ser Ser Ile Glu Ala Pro Gly Glu Lys Glu Pro Ile 50 55 60 Val Glu Val Ile Glu Asn Trp Pro Gly Ser Leu Arg Pro Asp Asp Leu 65 70 75 80 Thr Pro Glu Glu Arg Val Pro Gly Ile Val Asn Arg Gly Arg Ile Ile 85 90 95 Val Gly Val Asp Gln Ser Gln Asn Leu Leu Ser Phe Arg Asp Pro Val 100 105 110 Thr Gly Glu Leu Arg Gly Phe Glu Val Glu Leu Ala Arg Glu Ile Ser 115 120 125 Arg Asp Ile Phe Gly Asp Pro Asn Lys Val Asp Phe Arg Phe Val Gly 130 135 140 Ser Ser Asp Arg Leu Arg Ser Leu Asp Gln Gly Asp Val Asp Ile Val 145 150 155 160 Ile Arg Ser Val Thr Ile Thr Asp Glu Arg Ala Lys Leu Val Glu Phe 165 170 175 Ser Thr Pro Tyr Leu Arg Thr Gln Thr Arg Met Leu Thr Met Glu Ser 180 185 190 Ser Gly Ile Thr Ser Ile Ala Asp Leu Pro Gly His Thr Ile Cys Val 195 200 205 Thr Asp Gly Ser Thr Ser Leu Gln Arg Ala Arg Thr Ile Ala Pro Glu 210 215 220 Ala Ser Ile Leu Lys Thr Arg Asn Trp Ser Asp Cys Leu Met Ala Leu 225 230 235 240 Gln Gln His Gln Ala Gln Val Ile Leu Gly Asp Asp Val Ile Leu Ser 245 250 255 Gly Ile Ala Ala Gln Asp Pro Tyr Thr Glu Ile Leu Asp Thr Ser Leu 260 265 270 Asp Ser His Ser Tyr Gly Val Ala Ala Ala Ser Thr Thr Ala Glu Thr 275 280 285 Asp Ser Ser Gly Leu Ile Arg Gln Val Asn Tyr Thr Ile Glu Arg Ile 290 295 300 Arg Thr Asp Arg Met Trp Trp Thr Met Phe Asp Asp Trp Phe Gly Pro 305 310 315 320 Tyr Leu Trp Ser Tyr Gly Pro Pro Gln Leu Gln Tyr Met Pro Glu Glu 325 330 335 Glu Gly Thr Glu Asn Asp Glu Gly 340 <210> 107 <211> 1035 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1012) <223> RXA00727 <400> 107 ttattgcacc atggcaggta gtattttgcc catgattgag agtttcaccc gattgcgaat 60 ttcgcagaca ccgcctctga aacggctact gcatagcact ttg cgt ttc ccc aaa 115 Leu Arg Phe Pro Lys 1 5 atc ccc aag cgc gct gta gcg gcg acc gtc ggc atc gtg gca acc tca 163 Ile Pro Lys Arg Ala Val Ala Ala Thr Val Gly Ile Val Ala Thr Ser 10 15 20 ttc acc ttg gct tct tgt gtc acc aat gag gag cag ggc aac cca gat 211 Phe Thr Leu Ala Ser Cys Val Thr Asn Glu Glu Gln Gly Asn Pro Asp 25 30 35 ggc tgg gag cag atc gtt cca gat cct gta ccg gag att cag gcg atg 259 Gly Trp Glu Gln Ile Val Pro Asp Pro Val Pro Glu Ile Gln Ala Met 40 45 50 gtt ccc gaa gct ctg gct cag cgc ggt gtg ctc acc gcc ggt gcc aac 307 Val Pro Glu Ala Leu Ala Gln Arg Gly Val Leu Thr Ala Gly Ala Asn 55 60 65 cca cct ttc cca ccg ttt gag ttt aaa gat tcc gat ggt cag att atc 355 Pro Pro Phe Pro Pro Phe Glu Phe Lys Asp Ser Asp Gly Gln Ile Ile 70 75 80 85 ggt gtg gaa atg gac ctc gtg cgt gca atg gcg ggg gtg atg ggc ttg 403 Gly Val Glu Met Asp Leu Val Arg Ala Met Ala Gly Val Met Gly Leu 90 95 100 gag ttc agc cct cag gag cag gat ttc tcc ctc atc ctt cca tcg gtt 451 Glu Phe Ser Pro Gln Glu Gln Asp Phe Ser Leu Ile Leu Pro Ser Val 105 110 115 caa gct ggc acc ctt gat atc gga gcc tct ggc ttc act gac aac gag 499 Gln Ala Gly Thr Leu Asp Ile Gly Ala Ser Gly Phe Thr Asp Asn Glu 120 125 130 gaa cgc cgc gag aac ttt gat ttc atc gat ttc ctc ttc gca ggt gtg 547 Glu Arg Arg Glu Asn Phe Asp Phe Ile Asp Phe Leu Phe Ala Gly Val 135 140 145 cag tgg gcg cag gca act gat cgt gaa acc cca atc gat ccg gaa aac 595 Gln Trp Ala Gln Ala Thr Asp Arg Glu Thr Pro Ile Asp Pro Glu Asn 150 155 160 165 gcc tgt ggt ctc acc gtt gct gta cag cgc aca acc gtg gca gag acc 643 Ala Cys Gly Leu Thr Val Ala Val Gln Arg Thr Thr Val Ala Glu Thr 170 175 180 gac gat gtc cgt cct cgc tca gct caa tgt gaa gcc gaa ggc aaa gag 691 Asp Asp Val Arg Pro Arg Ser Ala Gln Cys Glu Ala Glu Gly Lys Glu 185 190 195 ccg atc acc att ttg tct tat gaa acc gca gat act gca gct acc gca 739 Pro Ile Thr Ile Leu Ser Tyr Glu Thr Ala Asp Thr Ala Ala Thr Ala 200 205 210 ttg atc ctg gga cgc gca gac gca ctt gct gcg gac tcc cct gtt tca 787 Leu Ile Leu Gly Arg Ala Asp Ala Leu Ala Ala Asp Ser Pro Val Ser 215 220 225 gct tgg gct gca gag cgc tcc gaa ggc cgc atc gaa gtt gtg ggc gat 835 Ala Trp Ala Ala Glu Arg Ser Glu Gly Arg Ile Glu Val Val Gly Asp 230 235 240 245 atg tac ttg gct gcg cca ttt ggt ttc gca ttc ccg ttg gaa tct gac 883 Met Tyr Leu Ala Ala Pro Phe Gly Phe Ala Phe Pro Leu Glu Ser Asp 250 255 260 ctc acc cca gca gca gct gcg gcg ttc caa cac ttg att gac acc ggc 931 Leu Thr Pro Ala Ala Ala Ala Ala Phe Gln His Leu Ile Asp Thr Gly 265 270 275 gat tac cag cgc atc atg gcg caa tgg ggc att gaa gaa ggc ctt ctt 979 Asp Tyr Gln Arg Ile Met Ala Gln Trp Gly Ile Glu Glu Gly Leu Leu 280 285 290 gat gag gcc ctg atc aac gaa cag cca ctc aac tagagccttc cagcaactaa 1032 Asp Glu Ala Leu Ile Asn Glu Gln Pro Leu Asn 295 300 aaa 1035 <210> 108 <211> 304 <212> PRT <213> Corynebacterium glutamicum <400> 108 Leu Arg Phe Pro Lys Ile Pro Lys Arg Ala Val Ala Ala Thr Val Gly 1 5 10 15 Ile Val Ala Thr Ser Phe Thr Leu Ala Ser Cys Val Thr Asn Glu Glu 20 25 30 Gln Gly Asn Pro Asp Gly Trp Glu Gln Ile Val Pro Asp Pro Val Pro 35 40 45 Glu Ile Gln Ala Met Val Pro Glu Ala Leu Ala Gln Arg Gly Val Leu 50 55 60 Thr Ala Gly Ala Asn Pro Pro Phe Pro Pro Phe Glu Phe Lys Asp Ser 65 70 75 80 Asp Gly Gln Ile Ile Gly Val Glu Met Asp Leu Val Arg Ala Met Ala 85 90 95 Gly Val Met Gly Leu Glu Phe Ser Pro Gln Glu Gln Asp Phe Ser Leu 100 105 110 Ile Leu Pro Ser Val Gln Ala Gly Thr Leu Asp Ile Gly Ala Ser Gly 115 120 125 Phe Thr Asp Asn Glu Glu Arg Arg Glu Asn Phe Asp Phe Ile Asp Phe 130 135 140 Leu Phe Ala Gly Val Gln Trp Ala Gln Ala Thr Asp Arg Glu Thr Pro 145 150 155 160 Ile Asp Pro Glu Asn Ala Cys Gly Leu Thr Val Ala Val Gln Arg Thr 165 170 175 Thr Val Ala Glu Thr Asp Asp Val Arg Pro Arg Ser Ala Gln Cys Glu 180 185 190 Ala Glu Gly Lys Glu Pro Ile Thr Ile Leu Ser Tyr Glu Thr Ala Asp 195 200 205 Thr Ala Ala Thr Ala Leu Ile Leu Gly Arg Ala Asp Ala Leu Ala Ala 210 215 220 Asp Ser Pro Val Ser Ala Trp Ala Ala Glu Arg Ser Glu Gly Arg Ile 225 230 235 240 Glu Val Val Gly Asp Met Tyr Leu Ala Ala Pro Phe Gly Phe Ala Phe 245 250 255 Pro Leu Glu Ser Asp Leu Thr Pro Ala Ala Ala Ala Ala Phe Gln His 260 265 270 Leu Ile Asp Thr Gly Asp Tyr Gln Arg Ile Met Ala Gln Trp Gly Ile 275 280 285 Glu Glu Gly Leu Leu Asp Glu Ala Leu Ile Asn Glu Gln Pro Leu Asn 290 295 300 <210> 109 <211> 1962 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1939) <223> RXA02139 <400> 109 tcaggaggat ttttcaatca tgtgcggcct tcttggcata ttgactgcaa atgggaacgc 60 tgaagcattc gttcctgcac tcgagcgggc cttgccatgc atg cgc cac cgt ggt 115 Met Arg His Arg Gly 1 5 cct gac gat gcc ggc act tgg cat gac gcc gat gca gcg ttt gga ttc 163 Pro Asp Asp Ala Gly Thr Trp His Asp Ala Asp Ala Ala Phe Gly Phe 10 15 20 aac cgc ctc tcc atc att gat att gca cac tcc cac caa cca ctg cgt 211 Asn Arg Leu Ser Ile Ile Asp Ile Ala His Ser His Gln Pro Leu Arg 25 30 35 tgg gga cct gcg gat gaa ccc gac cgc tac gca atg act ttc aac ggt 259 Trp Gly Pro Ala Asp Glu Pro Asp Arg Tyr Ala Met Thr Phe Asn Gly 40 45 50 gag atc tac aac tac gtt gag ctg cgt aaa gag ctc tcg gat ttg gga 307 Glu Ile Tyr Asn Tyr Val Glu Leu Arg Lys Glu Leu Ser Asp Leu Gly 55 60 65 tat gcc ttt aat act tct ggc gat ggc gag cca att gtt gtc ggt ttc 355 Tyr Ala Phe Asn Thr Ser Gly Asp Gly Glu Pro Ile Val Val Gly Phe 70 75 80 85 cac cac tgg ggc gag tcc gtg gtc gag cat ctc cgc gga atg ttc ggc 403 His His Trp Gly Glu Ser Val Val Glu His Leu Arg Gly Met Phe Gly 90 95 100 att gcc att tgg gat aca aag gaa aag tcg ctt ttc ctt gcg cgt gat 451 Ile Ala Ile Trp Asp Thr Lys Glu Lys Ser Leu Phe Leu Ala Arg Asp 105 110 115 cag ttc ggc att aag cca ctg ttc tac gca acc acc gag cat ggc acc 499 Gln Phe Gly Ile Lys Pro Leu Phe Tyr Ala Thr Thr Glu His Gly Thr 120 125 130 gtg ttc tcc tca gag aag aag acc atc ttg gag atg gcc gag gag atg 547 Val Phe Ser Ser Glu Lys Lys Thr Ile Leu Glu Met Ala Glu Glu Met 135 140 145 aat cta gat ctg ggc ctt gat aag cgc acc att gag cac tac gtg gac 595 Asn Leu Asp Leu Gly Leu Asp Lys Arg Thr Ile Glu His Tyr Val Asp 150 155 160 165 ttg cag tac gtg ccc gag cca gat acc ctt cac gcg cag att tcc cgc 643 Leu Gln Tyr Val Pro Glu Pro Asp Thr Leu His Ala Gln Ile Ser Arg 170 175 180 ttg gag tca ggc tgc acc gca aca gtt cgt ccg ggc ggc aag ctg gaa 691 Leu Glu Ser Gly Cys Thr Ala Thr Val Arg Pro Gly Gly Lys Leu Glu 185 190 195 cag aag cgt tac ttc aag cct cag ttc cca gta cag aag gtc gta aag 739 Gln Lys Arg Tyr Phe Lys Pro Gln Phe Pro Val Gln Lys Val Val Lys 200 205 210 ggt aag gag cag gac ctc ttc gat cgc att gcc cag gtg ttg gag gat 787 Gly Lys Glu Gln Asp Leu Phe Asp Arg Ile Ala Gln Val Leu Glu Asp 215 220 225 agc gtc gaa aag cat atg cgt gcc gac gtg acc gta ggc tcg ttc ctt 835 Ser Val Glu Lys His Met Arg Ala Asp Val Thr Val Gly Ser Phe Leu 230 235 240 245 ttc ggc ggc att gac tca acc gca att gcg gcg ctt gca aag cgc cac 883 Phe Gly Gly Ile Asp Ser Thr Ala Ile Ala Ala Leu Ala Lys Arg His 250 255 260 aac cct gac ctg ctc acc ttc acc acc ggt ttc gag cgt gaa ggc tac 931 Asn Pro Asp Leu Leu Thr Phe Thr Thr Gly Phe Glu Arg Glu Gly Tyr 265 270 275 tcg gag gtc gat gtg gct gcg gag tcc gcc gct gcg att ggc gct gag 979 Ser Glu Val Asp Val Ala Ala Glu Ser Ala Ala Ala Ile Gly Ala Glu 280 285 290 cac atc gtg aag att gtc tcg cct gag gaa tac gcc aac gcg att cct 1027 His Ile Val Lys Ile Val Ser Pro Glu Glu Tyr Ala Asn Ala Ile Pro 295 300 305 aag atc atg tgg tac ttg gat gat cct gta gct gac cca tca ttg gtc 1075 Lys Ile Met Trp Tyr Leu Asp Asp Pro Val Ala Asp Pro Ser Leu Val 310 315 320 325 ccg ctg tac ttc gtg gca gcg gaa gca cgt aag cac gtc aag gtt gtg 1123 Pro Leu Tyr Phe Val Ala Ala Glu Ala Arg Lys His Val Lys Val Val 330 335 340 ctg tct ggc gag ggc gca gat gag ctg ttc ggt gga tac acc att tac 1171 Leu Ser Gly Glu Gly Ala Asp Glu Leu Phe Gly Gly Tyr Thr Ile Tyr 345 350 355 aag gag ccg cta tcg ctt gct cca ttt gag aag atc cct tcc cca cta 1219 Lys Glu Pro Leu Ser Leu Ala Pro Phe Glu Lys Ile Pro Ser Pro Leu 360 365 370 cgt aaa ggc ctg gga aag ctc agc aag gtt ctg cca gac ggc atg aag 1267 Arg Lys Gly Leu Gly Lys Leu Ser Lys Val Leu Pro Asp Gly Met Lys 375 380 385 ggc aag tcc ctt ctt gag cgt ggc tcc atg acc atg gaa gag cgc tac 1315 Gly Lys Ser Leu Leu Glu Arg Gly Ser Met Thr Met Glu Glu Arg Tyr 390 395 400 405 tac ggc aac gct cgc tcc ttc aat ttc gag cag atg caa cgc gtt att 1363 Tyr Gly Asn Ala Arg Ser Phe Asn Phe Glu Gln Met Gln Arg Val Ile 410 415 420 cca tgg gca aag cgc gaa tgg gac cac cgc gaa gtc act gcg ccg atc 1411 Pro Trp Ala Lys Arg Glu Trp Asp His Arg Glu Val Thr Ala Pro Ile 425 430 435 tac gca cag tcc cgc aac ttt gat cca gta gcc cgc atg caa cac ctg 1459 Tyr Ala Gln Ser Arg Asn Phe Asp Pro Val Ala Arg Met Gln His Leu 440 445 450 gat ctg ttc acc tgg atg cgc ggc gac atc ctg gtc aag gct gac aag 1507 Asp Leu Phe Thr Trp Met Arg Gly Asp Ile Leu Val Lys Ala Asp Lys 455 460 465 atc aac atg gcg aac tcc ctt gag ctg cga gtt cca ttc ttg gat aag 1555 Ile Asn Met Ala Asn Ser Leu Glu Leu Arg Val Pro Phe Leu Asp Lys 470 475 480 485 gaa gtt ttc aag gtt gca gag acc att cct tac gac ctg aag att gcc 1603 Glu Val Phe Lys Val Ala Glu Thr Ile Pro Tyr Asp Leu Lys Ile Ala 490 495 500 aac ggt acc acc aag tac gcg ctg cgc agg gca ctc gag cag att gtt 1651 Asn Gly Thr Thr Lys Tyr Ala Leu Arg Arg Ala Leu Glu Gln Ile Val 505 510 515 ccg cct cac gtt ttg cac cgc aag aag ctg ggc ttc cct gtt ccc atg 1699 Pro Pro His Val Leu His Arg Lys Lys Leu Gly Phe Pro Val Pro Met 520 525 530 cgc cac tgg ctt gcc ggc gat gag ctg ttc ggt tgg gcg cag gac acc 1747 Arg His Trp Leu Ala Gly Asp Glu Leu Phe Gly Trp Ala Gln Asp Thr 535 540 545 atc aag gaa tcc ggt act gaa gat atc ttc aac aag cag gct gtg ctg 1795 Ile Lys Glu Ser Gly Thr Glu Asp Ile Phe Asn Lys Gln Ala Val Leu 550 555 560 565 gat atg ctg aac gag cac cgc gat ggc gtg tca gat cat tcc cgt cga 1843 Asp Met Leu Asn Glu His Arg Asp Gly Val Ser Asp His Ser Arg Arg 570 575 580 ctg tgg act gtt ctg tca ttt atg gtg tgg cac ggc att ttt gtg gaa 1891 Leu Trp Thr Val Leu Ser Phe Met Val Trp His Gly Ile Phe Val Glu 585 590 595 aac cgc att gat cca cag att gag gac cgc tcc tac cca gtc gag ctt 1939 Asn Arg Ile Asp Pro Gln Ile Glu Asp Arg Ser Tyr Pro Val Glu Leu 600 605 610 taagtcttaa agcctaaacc ccc 1962 <210> 110 <211> 613 <212> PRT <213> Corynebacterium glutamicum <400> 110 Met Arg His Arg Gly Pro Asp Asp Ala Gly Thr Trp His Asp Ala Asp 1 5 10 15 Ala Ala Phe Gly Phe Asn Arg Leu Ser Ile Ile Asp Ile Ala His Ser 20 25 30 His Gln Pro Leu Arg Trp Gly Pro Ala Asp Glu Pro Asp Arg Tyr Ala 35 40 45 Met Thr Phe Asn Gly Glu Ile Tyr Asn Tyr Val Glu Leu Arg Lys Glu 50 55 60 Leu Ser Asp Leu Gly Tyr Ala Phe Asn Thr Ser Gly Asp Gly Glu Pro 65 70 75 80 Ile Val Val Gly Phe His His Trp Gly Glu Ser Val Val Glu His Leu 85 90 95 Arg Gly Met Phe Gly Ile Ala Ile Trp Asp Thr Lys Glu Lys Ser Leu 100 105 110 Phe Leu Ala Arg Asp Gln Phe Gly Ile Lys Pro Leu Phe Tyr Ala Thr 115 120 125 Thr Glu His Gly Thr Val Phe Ser Ser Glu Lys Lys Thr Ile Leu Glu 130 135 140 Met Ala Glu Glu Met Asn Leu Asp Leu Gly Leu Asp Lys Arg Thr Ile 145 150 155 160 Glu His Tyr Val Asp Leu Gln Tyr Val Pro Glu Pro Asp Thr Leu His 165 170 175 Ala Gln Ile Ser Arg Leu Glu Ser Gly Cys Thr Ala Thr Val Arg Pro 180 185 190 Gly Gly Lys Leu Glu Gln Lys Arg Tyr Phe Lys Pro Gln Phe Pro Val 195 200 205 Gln Lys Val Val Lys Gly Lys Glu Gln Asp Leu Phe Asp Arg Ile Ala 210 215 220 Gln Val Leu Glu Asp Ser Val Glu Lys His Met Arg Ala Asp Val Thr 225 230 235 240 Val Gly Ser Phe Leu Phe Gly Gly Ile Asp Ser Thr Ala Ile Ala Ala 245 250 255 Leu Ala Lys Arg His Asn Pro Asp Leu Leu Thr Phe Thr Thr Gly Phe 260 265 270 Glu Arg Glu Gly Tyr Ser Glu Val Asp Val Ala Ala Glu Ser Ala Ala 275 280 285 Ala Ile Gly Ala Glu His Ile Val Lys Ile Val Ser Pro Glu Glu Tyr 290 295 300 Ala Asn Ala Ile Pro Lys Ile Met Trp Tyr Leu Asp Asp Pro Val Ala 305 310 315 320 Asp Pro Ser Leu Val Pro Leu Tyr Phe Val Ala Ala Glu Ala Arg Lys 325 330 335 His Val Lys Val Val Leu Ser Gly Glu Gly Ala Asp Glu Leu Phe Gly 340 345 350 Gly Tyr Thr Ile Tyr Lys Glu Pro Leu Ser Leu Ala Pro Phe Glu Lys 355 360 365 Ile Pro Ser Pro Leu Arg Lys Gly Leu Gly Lys Leu Ser Lys Val Leu 370 375 380 Pro Asp Gly Met Lys Gly Lys Ser Leu Leu Glu Arg Gly Ser Met Thr 385 390 395 400 Met Glu Glu Arg Tyr Tyr Gly Asn Ala Arg Ser Phe Asn Phe Glu Gln 405 410 415 Met Gln Arg Val Ile Pro Trp Ala Lys Arg Glu Trp Asp His Arg Glu 420 425 430 Val Thr Ala Pro Ile Tyr Ala Gln Ser Arg Asn Phe Asp Pro Val Ala 435 440 445 Arg Met Gln His Leu Asp Leu Phe Thr Trp Met Arg Gly Asp Ile Leu 450 455 460 Val Lys Ala Asp Lys Ile Asn Met Ala Asn Ser Leu Glu Leu Arg Val 465 470 475 480 Pro Phe Leu Asp Lys Glu Val Phe Lys Val Ala Glu Thr Ile Pro Tyr 485 490 495 Asp Leu Lys Ile Ala Asn Gly Thr Thr Lys Tyr Ala Leu Arg Arg Ala 500 505 510 Leu Glu Gln Ile Val Pro Pro His Val Leu His Arg Lys Lys Leu Gly 515 520 525 Phe Pro Val Pro Met Arg His Trp Leu Ala Gly Asp Glu Leu Phe Gly 530 535 540 Trp Ala Gln Asp Thr Ile Lys Glu Ser Gly Thr Glu Asp Ile Phe Asn 545 550 555 560 Lys Gln Ala Val Leu Asp Met Leu Asn Glu His Arg Asp Gly Val Ser 565 570 575 Asp His Ser Arg Arg Leu Trp Thr Val Leu Ser Phe Met Val Trp His 580 585 590 Gly Ile Phe Val Glu Asn Arg Ile Asp Pro Gln Ile Glu Asp Arg Ser 595 600 605 Tyr Pro Val Glu Leu 610 <210> 111 <211> 1284 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1261) <223> RXN00116 <400> 111 cgcggcacgc acgctggggg caagcgtcga caagcacaaa ctttttgctt aattgaatcc 60 tttgcgcacc aatcaatggg ggatcaaata tagtagctgc atg agt aat gac ttc 115 Met Ser Asn Asp Phe 1 5 gtc gtt tct agg ctt aga ccc ttt ggt gaa acg att ttt gca acc atg 163 Val Val Ser Arg Leu Arg Pro Phe Gly Glu Thr Ile Phe Ala Thr Met 10 15 20 acc cag cga gct gtt gag gcg ggt gca atc aat ctt ggt cag ggc ttt 211 Thr Gln Arg Ala Val Glu Ala Gly Ala Ile Asn Leu Gly Gln Gly Phe 25 30 35 cct gat gag gat ggt cct cgt cgg atg tta gag atc gcg tcg gag cag 259 Pro Asp Glu Asp Gly Pro Arg Arg Met Leu Glu Ile Ala Ser Glu Gln 40 45 50 att ctc ggg gga aat aat cag tat tcg gcg ggg cgt ggg gat gct tcg 307 Ile Leu Gly Gly Asn Asn Gln Tyr Ser Ala Gly Arg Gly Asp Ala Ser 55 60 65 ttg agg gca gct gtg gct cgt gat cat ttg gag agg ttt gat ctg gag 355 Leu Arg Ala Ala Val Ala Arg Asp His Leu Glu Arg Phe Asp Leu Glu 70 75 80 85 tac aac cct gat tcg gag gtg ttg atc acg gtg ggg gcc act gag gcg 403 Tyr Asn Pro Asp Ser Glu Val Leu Ile Thr Val Gly Ala Thr Glu Ala 90 95 100 att acg gcg act gtg ttg ggt ttg gtg gag cct ggg gat gaa gtg atc 451 Ile Thr Ala Thr Val Leu Gly Leu Val Glu Pro Gly Asp Glu Val Ile 105 110 115 gtt ttg gaa ccg tat tac gat gcg tat gcg gcg gct att gcg ttg gcg 499 Val Leu Glu Pro Tyr Tyr Asp Ala Tyr Ala Ala Ala Ile Ala Leu Ala 120 125 130 ggg gcg acg cgg gtg gcg gtt cct ttg cag gag gtg gag aac tcg tgg 547 Gly Ala Thr Arg Val Ala Val Pro Leu Gln Glu Val Glu Asn Ser Trp 135 140 145 gat gtg gat gtc gat aag ttg cat gcg gcg gtg act aag aag acg cgg 595 Asp Val Asp Val Asp Lys Leu His Ala Ala Val Thr Lys Lys Thr Arg 150 155 160 165 atg att atc gtt aat tcg ccg cat aat ccg acg ggt tcg gtg ttt tct 643 Met Ile Ile Val Asn Ser Pro His Asn Pro Thr Gly Ser Val Phe Ser 170 175 180 aag aag gcg ttg aag cag ttg gcg ggt gtt gct cgt gcg tat gac ttg 691 Lys Lys Ala Leu Lys Gln Leu Ala Gly Val Ala Arg Ala Tyr Asp Leu 185 190 195 ttg gtg ttg tca gat gag gtg tat gag cat ctt gtt ttt gat gat cag 739 Leu Val Leu Ser Asp Glu Val Tyr Glu His Leu Val Phe Asp Asp Gln 200 205 210 aag cat gtg agt gtc gcg aag ctg ccc ggt atg tgg gat cgc acg gtg 787 Lys His Val Ser Val Ala Lys Leu Pro Gly Met Trp Asp Arg Thr Val 215 220 225 acg gtg tcg tcg gcg gcg aaa acg ttc aat gtg act ggt tgg aag acg 835 Thr Val Ser Ser Ala Ala Lys Thr Phe Asn Val Thr Gly Trp Lys Thr 230 235 240 245 ggg tgg gcg ttg gca ccg gag ccg ttg ttg gag gcg gtg ttg aag gcg 883 Gly Trp Ala Leu Ala Pro Glu Pro Leu Leu Glu Ala Val Leu Lys Ala 250 255 260 aag cag ttt atg tct tat gtg ggg gct aca cct ttt cag ccg gct gtg 931 Lys Gln Phe Met Ser Tyr Val Gly Ala Thr Pro Phe Gln Pro Ala Val 265 270 275 gcg cat gcg att gaa cat gag cag aag tgg gtg tca aag atg tct aag 979 Ala His Ala Ile Glu His Glu Gln Lys Trp Val Ser Lys Met Ser Lys 280 285 290 ggg ctt gag ctc aag cgg gat att ttg cgt act gcg tta gat aag gcg 1027 Gly Leu Glu Leu Lys Arg Asp Ile Leu Arg Thr Ala Leu Asp Lys Ala 295 300 305 ggg ctg aag act cat gac agt atg ggc acg tat ttc atc gtt gcg gat 1075 Gly Leu Lys Thr His Asp Ser Met Gly Thr Tyr Phe Ile Val Ala Asp 310 315 320 325 att ggg gat cgt gat ggt gcg gag ttc tgt ttt gag ttg att gag aag 1123 Ile Gly Asp Arg Asp Gly Ala Glu Phe Cys Phe Glu Leu Ile Glu Lys 330 335 340 gtt ggg gtg gcg gcg att ccg gtg cag gcg ttt gtg gat cat ccg aag 1171 Val Gly Val Ala Ala Ile Pro Val Gln Ala Phe Val Asp His Pro Lys 345 350 355 aag tgg tcg tcg aag gtt cgt ttt gcg ttt tgc aaa aaa gaa gag acg 1219 Lys Trp Ser Ser Lys Val Arg Phe Ala Phe Cys Lys Lys Glu Glu Thr 360 365 370 ctc cgc gaa gct gcg gag cgt ctc aag ggg att aag aaa cta 1261 Leu Arg Glu Ala Ala Glu Arg Leu Lys Gly Ile Lys Lys Leu 375 380 385 tagtttgaac aggttgttgg ggg 1284 <210> 112 <211> 387 <212> PRT <213> Corynebacterium glutamicum <400> 112 Met Ser Asn Asp Phe Val Val Ser Arg Leu Arg Pro Phe Gly Glu Thr 1 5 10 15 Ile Phe Ala Thr Met Thr Gln Arg Ala Val Glu Ala Gly Ala Ile Asn 20 25 30 Leu Gly Gln Gly Phe Pro Asp Glu Asp Gly Pro Arg Arg Met Leu Glu 35 40 45 Ile Ala Ser Glu Gln Ile Leu Gly Gly Asn Asn Gln Tyr Ser Ala Gly 50 55 60 Arg Gly Asp Ala Ser Leu Arg Ala Ala Val Ala Arg Asp His Leu Glu 65 70 75 80 Arg Phe Asp Leu Glu Tyr Asn Pro Asp Ser Glu Val Leu Ile Thr Val 85 90 95 Gly Ala Thr Glu Ala Ile Thr Ala Thr Val Leu Gly Leu Val Glu Pro 100 105 110 Gly Asp Glu Val Ile Val Leu Glu Pro Tyr Tyr Asp Ala Tyr Ala Ala 115 120 125 Ala Ile Ala Leu Ala Gly Ala Thr Arg Val Ala Val Pro Leu Gln Glu 130 135 140 Val Glu Asn Ser Trp Asp Val Asp Val Asp Lys Leu His Ala Ala Val 145 150 155 160 Thr Lys Lys Thr Arg Met Ile Ile Val Asn Ser Pro His Asn Pro Thr 165 170 175 Gly Ser Val Phe Ser Lys Lys Ala Leu Lys Gln Leu Ala Gly Val Ala 180 185 190 Arg Ala Tyr Asp Leu Leu Val Leu Ser Asp Glu Val Tyr Glu His Leu 195 200 205 Val Phe Asp Asp Gln Lys His Val Ser Val Ala Lys Leu Pro Gly Met 210 215 220 Trp Asp Arg Thr Val Thr Val Ser Ser Ala Ala Lys Thr Phe Asn Val 225 230 235 240 Thr Gly Trp Lys Thr Gly Trp Ala Leu Ala Pro Glu Pro Leu Leu Glu 245 250 255 Ala Val Leu Lys Ala Lys Gln Phe Met Ser Tyr Val Gly Ala Thr Pro 260 265 270 Phe Gln Pro Ala Val Ala His Ala Ile Glu His Glu Gln Lys Trp Val 275 280 285 Ser Lys Met Ser Lys Gly Leu Glu Leu Lys Arg Asp Ile Leu Arg Thr 290 295 300 Ala Leu Asp Lys Ala Gly Leu Lys Thr His Asp Ser Met Gly Thr Tyr 305 310 315 320 Phe Ile Val Ala Asp Ile Gly Asp Arg Asp Gly Ala Glu Phe Cys Phe 325 330 335 Glu Leu Ile Glu Lys Val Gly Val Ala Ala Ile Pro Val Gln Ala Phe 340 345 350 Val Asp His Pro Lys Lys Trp Ser Ser Lys Val Arg Phe Ala Phe Cys 355 360 365 Lys Lys Glu Glu Thr Leu Arg Glu Ala Ala Glu Arg Leu Lys Gly Ile 370 375 380 Lys Lys Leu 385 <210> 113 <211> 607 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(607) <223> FRXA00116 <400> 113 tttgcgcacc aatcaatggg ggatcaaata tagtagctgc atgagtaatg acttcgtcgt 60 ttctaggctt agaccctttg gtgaaacgat ttttgcaacc atg acc cag cga gct 115 Met Thr Gln Arg Ala 1 5 gtt gag gcg ggt gca atc aat ctt ggt cag ggc ttt cct gat gag gat 163 Val Glu Ala Gly Ala Ile Asn Leu Gly Gln Gly Phe Pro Asp Glu Asp 10 15 20 ggt cct cgt cgg atg tta gag atc gcg tcg gag cag att ctc ggg gga 211 Gly Pro Arg Arg Met Leu Glu Ile Ala Ser Glu Gln Ile Leu Gly Gly 25 30 35 aat aat cag tat tcg gcg ggg cgt ggg gat gct tcg ttg agg gca gct 259 Asn Asn Gln Tyr Ser Ala Gly Arg Gly Asp Ala Ser Leu Arg Ala Ala 40 45 50 gtg gct cgt gat cat ttg gag agg ttt gat ctg gag tac aac cct gat 307 Val Ala Arg Asp His Leu Glu Arg Phe Asp Leu Glu Tyr Asn Pro Asp 55 60 65 tcg gag gtg ttg atc acg gtg ggg gcc act gag gcg att acg gcg act 355 Ser Glu Val Leu Ile Thr Val Gly Ala Thr Glu Ala Ile Thr Ala Thr 70 75 80 85 gtg ttg ggt ttg gtg gag cct ggg gat gaa gtg atc gtt ttg gaa ccg 403 Val Leu Gly Leu Val Glu Pro Gly Asp Glu Val Ile Val Leu Glu Pro 90 95 100 tat tac gat gcg tat gcg gcg gct att gcg ttg gcg ggg gcg acg cgg 451 Tyr Tyr Asp Ala Tyr Ala Ala Ala Ile Ala Leu Ala Gly Ala Thr Arg 105 110 115 gtg gcg gtt cct ttg cag gag gtg gag aac tcg tgg gat gtg gat gtc 499 Val Ala Val Pro Leu Gln Glu Val Glu Asn Ser Trp Asp Val Asp Val 120 125 130 gat aag ttg cat gcg gcg gtg act aag aag acg cgg atg att atc gtt 547 Asp Lys Leu His Ala Ala Val Thr Lys Lys Thr Arg Met Ile Ile Val 135 140 145 aat tcg ccg cat aat ccg acg ggt tcg gtg ttt tct aag aag gcg ttg 595 Asn Ser Pro His Asn Pro Thr Gly Ser Val Phe Ser Lys Lys Ala Leu 150 155 160 165 aag cag ttg gcg 607 Lys Gln Leu Ala <210> 114 <211> 169 <212> PRT <213> Corynebacterium glutamicum <400> 114 Met Thr Gln Arg Ala Val Glu Ala Gly Ala Ile Asn Leu Gly Gln Gly 1 5 10 15 Phe Pro Asp Glu Asp Gly Pro Arg Arg Met Leu Glu Ile Ala Ser Glu 20 25 30 Gln Ile Leu Gly Gly Asn Asn Gln Tyr Ser Ala Gly Arg Gly Asp Ala 35 40 45 Ser Leu Arg Ala Ala Val Ala Arg Asp His Leu Glu Arg Phe Asp Leu 50 55 60 Glu Tyr Asn Pro Asp Ser Glu Val Leu Ile Thr Val Gly Ala Thr Glu 65 70 75 80 Ala Ile Thr Ala Thr Val Leu Gly Leu Val Glu Pro Gly Asp Glu Val 85 90 95 Ile Val Leu Glu Pro Tyr Tyr Asp Ala Tyr Ala Ala Ala Ile Ala Leu 100 105 110 Ala Gly Ala Thr Arg Val Ala Val Pro Leu Gln Glu Val Glu Asn Ser 115 120 125 Trp Asp Val Asp Val Asp Lys Leu His Ala Ala Val Thr Lys Lys Thr 130 135 140 Arg Met Ile Ile Val Asn Ser Pro His Asn Pro Thr Gly Ser Val Phe 145 150 155 160 Ser Lys Lys Ala Leu Lys Gln Leu Ala 165 <210> 115 <211> 1230 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1207) <223> RXN00618 <400> 115 gctgcattag agggtcgtat ctcgatctaa aagcagtacg cagataggct tgtctcttat 60 gaagccaagc actagaagca atgttcagcc gtttcgcgtc atg cag atg ttg gac 115 Met Gln Met Leu Asp 1 5 cga gtc cac cgt cgc agg cgc gaa ggc aaa gac acc tta atg ttc tgc 163 Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp Thr Leu Met Phe Cys 10 15 20 gct ggc cag ccg tca act ggt gcg cca gaa gca gtc atc gaa gaa gca 211 Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala Val Ile Glu Glu Ala 25 30 35 gag atc gct ctt cgc tcg ggt cct ttg gga tac acc gag gtg att ggt 259 Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr Thr Glu Val Ile Gly 40 45 50 gat cgt gag ttc cgt gaa cgc atc gcc gat tgg cac tct gct act tat 307 Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp His Ser Ala Thr Tyr 55 60 65 gac gta gac acc aac cct gac aat gtt att gtc acc acc ggt tct tca 355 Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val Thr Thr Gly Ser Ser 70 75 80 85 ggt gga ttc gtg gca tcg ttt atc gcc acc ttg gat cac ggg gat tat 403 Gly Gly Phe Val Ala Ser Phe Ile Ala Thr Leu Asp His Gly Asp Tyr 90 95 100 gtg gca atg cct acc ccg ggg tac ccg gca tat cgc aat att ctg gaa 451 Val Ala Met Pro Thr Pro Gly Tyr Pro Ala Tyr Arg Asn Ile Leu Glu 105 110 115 tct ttg ggg gcg aag gtt ctg aac ctg cgc tgt act gca gag act cgt 499 Ser Leu Gly Ala Lys Val Leu Asn Leu Arg Cys Thr Ala Glu Thr Arg 120 125 130 ttc cag cca acc gct caa atg ttg gag gaa ctg cca cac aag ccg aag 547 Phe Gln Pro Thr Ala Gln Met Leu Glu Glu Leu Pro His Lys Pro Lys 135 140 145 gct gtt att gtc acc agc cca gga aac cca acg ggc acc atc att gat 595 Ala Val Ile Val Thr Ser Pro Gly Asn Pro Thr Gly Thr Ile Ile Asp 150 155 160 165 ccg gaa gag cta gag cgc atc gcc aag tgg tgc gat gac aat gat gct 643 Pro Glu Glu Leu Glu Arg Ile Ala Lys Trp Cys Asp Asp Asn Asp Ala 170 175 180 gtt ctt atc tct gat gag gac tac cac ggc atg agc ttt ggt cgt ccg 691 Val Leu Ile Ser Asp Glu Asp Tyr His Gly Met Ser Phe Gly Arg Pro 185 190 195 ctg gca act gcg cat cag ttt tcc aag aac gcc atc gtg gtg ggt acc 739 Leu Ala Thr Ala His Gln Phe Ser Lys Asn Ala Ile Val Val Gly Thr 200 205 210 ttg tcc aag tac ttc tcc atg acg ggt tgg cgc gtg ggt tgg atc atc 787 Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp Arg Val Gly Trp Ile Ile 215 220 225 gtt cca gat gag ctg gtc aca ccg att gaa aac ctg cag gct tct ctt 835 Val Pro Asp Glu Leu Val Thr Pro Ile Glu Asn Leu Gln Ala Ser Leu 230 235 240 245 tcc ttg tgt gct cct gcc atc ggg cag gct gcg gga cgc gca gcc ttc 883 Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala Ala Gly Arg Ala Ala Phe 250 255 260 act ttg gag gct ggg gcc gaa ctt gat gcc cac gtt gaa gcg tat cgc 931 Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala His Val Glu Ala Tyr Arg 265 270 275 gag gcc cgg gag gtg ttc gtc gat aag ctc cct gaa atc ggg ctt ggc 979 Glu Ala Arg Glu Val Phe Val Asp Lys Leu Pro Glu Ile Gly Leu Gly 280 285 290 act ttc gcc gac ccg gat ggc ggc ctg tat ttg tgg gtc gat gtt tct 1027 Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr Leu Trp Val Asp Val Ser 295 300 305 gca tac acc gat gat tca gag gaa tgg gca ttg cgt ttg ctc gat gaa 1075 Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala Leu Arg Leu Leu Asp Glu 310 315 320 325 gcg ggc gtg gcc gtc gcg ccg ggt gtt gat ttt gat cct gag gaa ggc 1123 Ala Gly Val Ala Val Ala Pro Gly Val Asp Phe Asp Pro Glu Glu Gly 330 335 340 cac aag tgg att cgt ttg agc ctg tgc gcg tca aag gaa gac acc att 1171 His Lys Trp Ile Arg Leu Ser Leu Cys Ala Ser Lys Glu Asp Thr Ile 345 350 355 gaa ggt gtg cgc aaa atc gga gaa ttc atc aaa aaa tagcagcgac 1217 Glu Gly Val Arg Lys Ile Gly Glu Phe Ile Lys Lys 360 365 taggttagtt tcg 1230 <210> 116 <211> 369 <212> PRT <213> Corynebacterium glutamicum <400> 116 Met Gln Met Leu Asp Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp 1 5 10 15 Thr Leu Met Phe Cys Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala 20 25 30 Val Ile Glu Glu Ala Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr 35 40 45 Thr Glu Val Ile Gly Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp 50 55 60 His Ser Ala Thr Tyr Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val 65 70 75 80 Thr Thr Gly Ser Ser Gly Gly Phe Val Ala Ser Phe Ile Ala Thr Leu 85 90 95 Asp His Gly Asp Tyr Val Ala Met Pro Thr Pro Gly Tyr Pro Ala Tyr 100 105 110 Arg Asn Ile Leu Glu Ser Leu Gly Ala Lys Val Leu Asn Leu Arg Cys 115 120 125 Thr Ala Glu Thr Arg Phe Gln Pro Thr Ala Gln Met Leu Glu Glu Leu 130 135 140 Pro His Lys Pro Lys Ala Val Ile Val Thr Ser Pro Gly Asn Pro Thr 145 150 155 160 Gly Thr Ile Ile Asp Pro Glu Glu Leu Glu Arg Ile Ala Lys Trp Cys 165 170 175 Asp Asp Asn Asp Ala Val Leu Ile Ser Asp Glu Asp Tyr His Gly Met 180 185 190 Ser Phe Gly Arg Pro Leu Ala Thr Ala His Gln Phe Ser Lys Asn Ala 195 200 205 Ile Val Val Gly Thr Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp Arg 210 215 220 Val Gly Trp Ile Ile Val Pro Asp Glu Leu Val Thr Pro Ile Glu Asn 225 230 235 240 Leu Gln Ala Ser Leu Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala Ala 245 250 255 Gly Arg Ala Ala Phe Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala His 260 265 270 Val Glu Ala Tyr Arg Glu Ala Arg Glu Val Phe Val Asp Lys Leu Pro 275 280 285 Glu Ile Gly Leu Gly Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr Leu 290 295 300 Trp Val Asp Val Ser Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala Leu 305 310 315 320 Arg Leu Leu Asp Glu Ala Gly Val Ala Val Ala Pro Gly Val Asp Phe 325 330 335 Asp Pro Glu Glu Gly His Lys Trp Ile Arg Leu Ser Leu Cys Ala Ser 340 345 350 Lys Glu Asp Thr Ile Glu Gly Val Arg Lys Ile Gly Glu Phe Ile Lys 355 360 365 Lys <210> 117 <211> 657 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(634) <223> FRXA00618 <400> 117 cccaacgggc accatcattg atccggaaga gctagagcgc atcgccaagt ggtgcgatga 60 caatgatgct gttcttatct ctgatgagga ctaccacggc atg agc ttt ggt cgt 115 Met Ser Phe Gly Arg 1 5 ccg ctg gca act gcg cat cag ttt tcc aag aac gcc atc gtg gtg ggt 163 Pro Leu Ala Thr Ala His Gln Phe Ser Lys Asn Ala Ile Val Val Gly 10 15 20 acc ttg tcc aag tac ttc tcc atg acg ggt tgg cgc gtg ggt tgg atc 211 Thr Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp Arg Val Gly Trp Ile 25 30 35 atc gtt cca gat gag ctg gtc aca ccg att gaa aac ctg cag gct tct 259 Ile Val Pro Asp Glu Leu Val Thr Pro Ile Glu Asn Leu Gln Ala Ser 40 45 50 ctt tcc ttg tgt gct cct gcc atc ggg cag gct gcg gga cgc gca gcc 307 Leu Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala Ala Gly Arg Ala Ala 55 60 65 ttc act ttg gag gct ggg gcc gaa ctt gat gcc cac gtt gaa gcg tat 355 Phe Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala His Val Glu Ala Tyr 70 75 80 85 cgc gag gcc cgg gag gtg ttc gtc gat aag ctc cct gaa atc ggg ctt 403 Arg Glu Ala Arg Glu Val Phe Val Asp Lys Leu Pro Glu Ile Gly Leu 90 95 100 ggc act ttc gcc gac ccg gat ggc ggc ctg tat ttg tgg gtc gat gtt 451 Gly Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr Leu Trp Val Asp Val 105 110 115 tct gca tac acc gat gat tca gag gaa tgg gca ttg cgt ttg ctc gat 499 Ser Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala Leu Arg Leu Leu Asp 120 125 130 gaa gcg ggc gtg gcc gtc gcg ccg ggt gtt gat ttt gat cct gag gaa 547 Glu Ala Gly Val Ala Val Ala Pro Gly Val Asp Phe Asp Pro Glu Glu 135 140 145 ggc cac aag tgg att cgt ttg agc ctg tgc gcg tca aag gaa gac acc 595 Gly His Lys Trp Ile Arg Leu Ser Leu Cys Ala Ser Lys Glu Asp Thr 150 155 160 165 att gaa ggt gtg cgc aaa atc gga gaa ttc atc aaa aaa tagcagcgac 644 Ile Glu Gly Val Arg Lys Ile Gly Glu Phe Ile Lys Lys 170 175 taggttagtt tcg 657 <210> 118 <211> 178 <212> PRT <213> Corynebacterium glutamicum <400> 118 Met Ser Phe Gly Arg Pro Leu Ala Thr Ala His Gln Phe Ser Lys Asn 1 5 10 15 Ala Ile Val Val Gly Thr Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp 20 25 30 Arg Val Gly Trp Ile Ile Val Pro Asp Glu Leu Val Thr Pro Ile Glu 35 40 45 Asn Leu Gln Ala Ser Leu Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala 50 55 60 Ala Gly Arg Ala Ala Phe Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala 65 70 75 80 His Val Glu Ala Tyr Arg Glu Ala Arg Glu Val Phe Val Asp Lys Leu 85 90 95 Pro Glu Ile Gly Leu Gly Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr 100 105 110 Leu Trp Val Asp Val Ser Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala 115 120 125 Leu Arg Leu Leu Asp Glu Ala Gly Val Ala Val Ala Pro Gly Val Asp 130 135 140 Phe Asp Pro Glu Glu Gly His Lys Trp Ile Arg Leu Ser Leu Cys Ala 145 150 155 160 Ser Lys Glu Asp Thr Ile Glu Gly Val Arg Lys Ile Gly Glu Phe Ile 165 170 175 Lys Lys <210> 119 <211> 385 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(385) <223> FRXA00627 <400> 119 gctgcattag agggtcgtat ctcgatctaa aagcagtacg cagataggct tgtctcttat 60 gaagccaagc actagaagca atgttcagcc gtttcgcgtc atg cag atg ttg gac 115 Met Gln Met Leu Asp 1 5 cga gtc cac cgt cgc agg cgc gaa ggc aaa gac acc tta atg ttc tgc 163 Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp Thr Leu Met Phe Cys 10 15 20 gct ggc cag ccg tca act ggt gcg cca gaa gca gtc atc gaa gaa gca 211 Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala Val Ile Glu Glu Ala 25 30 35 gag atc gct ctt cgc tcg ggt cct ttg gga tac acc gag gtg att ggt 259 Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr Thr Glu Val Ile Gly 40 45 50 gat cgt gag ttc cgt gaa cgc atc gcc gat tgg cac tct gct act tat 307 Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp His Ser Ala Thr Tyr 55 60 65 gac gta gac acc aac cct gac aat gtt att gtc acc acc ggt tct tca 355 Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val Thr Thr Gly Ser Ser 70 75 80 85 ggt gga ttc gtg gca tcg ttt atc gcc acc 385 Gly Gly Phe Val Ala Ser Phe Ile Ala Thr 90 95 <210> 120 <211> 95 <212> PRT <213> Corynebacterium glutamicum <400> 120 Met Gln Met Leu Asp Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp 1 5 10 15 Thr Leu Met Phe Cys Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala 20 25 30 Val Ile Glu Glu Ala Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr 35 40 45 Thr Glu Val Ile Gly Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp 50 55 60 His Ser Ala Thr Tyr Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val 65 70 75 80 Thr Thr Gly Ser Ser Gly Gly Phe Val Ala Ser Phe Ile Ala Thr 85 90 95 <210> 121 <211> 1434 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1411) <223> RXA02550 <400> 121 gatcttaggc agccgtggga ttacaccctt ttagagctag aacagtaaaa attcacccaa 60 tagctttcaa ctacgcacac aaagtggcaa cattgagcgg gtg act aca gac aag 115 Val Thr Thr Asp Lys 1 5 cgc aaa acc tct aag acc acc gac acc gcc aac aag gct gtg ggc gcg 163 Arg Lys Thr Ser Lys Thr Thr Asp Thr Ala Asn Lys Ala Val Gly Ala 10 15 20 gat cag gca gcg cgt ccc act cgg cga aca act cgc cgc atc ttc gat 211 Asp Gln Ala Ala Arg Pro Thr Arg Arg Thr Thr Arg Arg Ile Phe Asp 25 30 35 cag tcg gag aag atg aag gac gtg ctg tac gag atc cgt ggc ccg gtg 259 Gln Ser Glu Lys Met Lys Asp Val Leu Tyr Glu Ile Arg Gly Pro Val 40 45 50 gcc gcg gag gcg gaa cgc atg gag ctt gat ggg cat aac atc tta aag 307 Ala Ala Glu Ala Glu Arg Met Glu Leu Asp Gly His Asn Ile Leu Lys 55 60 65 ctc aac acg gga aat cca gcc gtg ttc gga ttc gat gcc ccc gac gtg 355 Leu Asn Thr Gly Asn Pro Ala Val Phe Gly Phe Asp Ala Pro Asp Val 70 75 80 85 att atg cgt gac atg atc gcc aac ctt cca act tcc caa ggg tat tcc 403 Ile Met Arg Asp Met Ile Ala Asn Leu Pro Thr Ser Gln Gly Tyr Ser 90 95 100 acc tcc aaa ggc att att ccg gcc cgg cga gca gtg gtc acc cgc tac 451 Thr Ser Lys Gly Ile Ile Pro Ala Arg Arg Ala Val Val Thr Arg Tyr 105 110 115 gaa gtt gtg ccc gga ttc ccc cac ttc gat gtt gat gat gtg ttc tta 499 Glu Val Val Pro Gly Phe Pro His Phe Asp Val Asp Asp Val Phe Leu 120 125 130 ggc aac ggt gtc tca gaa cta atc acc atg acc acc caa gca ctc ctc 547 Gly Asn Gly Val Ser Glu Leu Ile Thr Met Thr Thr Gln Ala Leu Leu 135 140 145 aac gac ggc gat gaa gtt ctt atc ccc gca ccg gac tac cca ctg tgg 595 Asn Asp Gly Asp Glu Val Leu Ile Pro Ala Pro Asp Tyr Pro Leu Trp 150 155 160 165 act gcc gca acc tcc ctg gct ggt ggt aag cct gtg cac tac ctc tgt 643 Thr Ala Ala Thr Ser Leu Ala Gly Gly Lys Pro Val His Tyr Leu Cys 170 175 180 gat gag gaa gat gac tgg aac cca tcc atc gaa gac atc aag tcc aaa 691 Asp Glu Glu Asp Asp Trp Asn Pro Ser Ile Glu Asp Ile Lys Ser Lys 185 190 195 atc tca gag aaa acc aaa gct att gtg gtg atc aac ccc aac aac ccc 739 Ile Ser Glu Lys Thr Lys Ala Ile Val Val Ile Asn Pro Asn Asn Pro 200 205 210 acg gga gct gtc tac ccg cgc cgg gtg ttg gaa caa atc gtc gag att 787 Thr Gly Ala Val Tyr Pro Arg Arg Val Leu Glu Gln Ile Val Glu Ile 215 220 225 gca cgc gag cat gac ctg ctg att ttg gcc gat gaa atc tac gac cgc 835 Ala Arg Glu His Asp Leu Leu Ile Leu Ala Asp Glu Ile Tyr Asp Arg 230 235 240 245 att ctc tac gat gat gcc gag cac atc agc ctg gca acc ctt gca cca 883 Ile Leu Tyr Asp Asp Ala Glu His Ile Ser Leu Ala Thr Leu Ala Pro 250 255 260 gat ctc ctt tgc atc aca tac aac ggt cta tcc aag gca tac cgc gtc 931 Asp Leu Leu Cys Ile Thr Tyr Asn Gly Leu Ser Lys Ala Tyr Arg Val 265 270 275 gca gga tac cga gct ggc tgg atg gta ttg act gga cca aag caa tac 979 Ala Gly Tyr Arg Ala Gly Trp Met Val Leu Thr Gly Pro Lys Gln Tyr 280 285 290 gca cgt gga ttt att gag ggc ctc gaa ctc ctc gca ggc act cga ctc 1027 Ala Arg Gly Phe Ile Glu Gly Leu Glu Leu Leu Ala Gly Thr Arg Leu 295 300 305 tgc cca aat gtc cca gct cag cac gct att cag gta gct ctg ggt gga 1075 Cys Pro Asn Val Pro Ala Gln His Ala Ile Gln Val Ala Leu Gly Gly 310 315 320 325 cgc cag tcc atc tac gac ctc act ggc gaa cac ggc cga ctc ctg gaa 1123 Arg Gln Ser Ile Tyr Asp Leu Thr Gly Glu His Gly Arg Leu Leu Glu 330 335 340 cag cgc aac atg gca tgg acg aaa ctc aac gaa atc cca ggt gtc agc 1171 Gln Arg Asn Met Ala Trp Thr Lys Leu Asn Glu Ile Pro Gly Val Ser 345 350 355 tgt gtg aaa cca atg gga gct cta tac gcg ttc ccc aag ctc gac ccc 1219 Cys Val Lys Pro Met Gly Ala Leu Tyr Ala Phe Pro Lys Leu Asp Pro 360 365 370 aac gtg tac gaa atc cac gac gac acc caa ctc atg ctg gat ctt ctc 1267 Asn Val Tyr Glu Ile His Asp Asp Thr Gln Leu Met Leu Asp Leu Leu 375 380 385 cgt gcc gag aaa atc ctc atg gtt cag ggc act ggc ttc aac tgg cca 1315 Arg Ala Glu Lys Ile Leu Met Val Gln Gly Thr Gly Phe Asn Trp Pro 390 395 400 405 cat cac gat cac ttc cga gtg gtc acc ctg cca tgg gca tcc cag ttg 1363 His His Asp His Phe Arg Val Val Thr Leu Pro Trp Ala Ser Gln Leu 410 415 420 gaa aac gca att gag cgc ctg ggt aac ttc ctg tcc act tac aag cag 1411 Glu Asn Ala Ile Glu Arg Leu Gly Asn Phe Leu Ser Thr Tyr Lys Gln 425 430 435 tagtagttgt taggattcac cac 1434 <210> 122 <211> 437 <212> PRT <213> Corynebacterium glutamicum <400> 122 Val Thr Thr Asp Lys Arg Lys Thr Ser Lys Thr Thr Asp Thr Ala Asn 1 5 10 15 Lys Ala Val Gly Ala Asp Gln Ala Ala Arg Pro Thr Arg Arg Thr Thr 20 25 30 Arg Arg Ile Phe Asp Gln Ser Glu Lys Met Lys Asp Val Leu Tyr Glu 35 40 45 Ile Arg Gly Pro Val Ala Ala Glu Ala Glu Arg Met Glu Leu Asp Gly 50 55 60 His Asn Ile Leu Lys Leu Asn Thr Gly Asn Pro Ala Val Phe Gly Phe 65 70 75 80 Asp Ala Pro Asp Val Ile Met Arg Asp Met Ile Ala Asn Leu Pro Thr 85 90 95 Ser Gln Gly Tyr Ser Thr Ser Lys Gly Ile Ile Pro Ala Arg Arg Ala 100 105 110 Val Val Thr Arg Tyr Glu Val Val Pro Gly Phe Pro His Phe Asp Val 115 120 125 Asp Asp Val Phe Leu Gly Asn Gly Val Ser Glu Leu Ile Thr Met Thr 130 135 140 Thr Gln Ala Leu Leu Asn Asp Gly Asp Glu Val Leu Ile Pro Ala Pro 145 150 155 160 Asp Tyr Pro Leu Trp Thr Ala Ala Thr Ser Leu Ala Gly Gly Lys Pro 165 170 175 Val His Tyr Leu Cys Asp Glu Glu Asp Asp Trp Asn Pro Ser Ile Glu 180 185 190 Asp Ile Lys Ser Lys Ile Ser Glu Lys Thr Lys Ala Ile Val Val Ile 195 200 205 Asn Pro Asn Asn Pro Thr Gly Ala Val Tyr Pro Arg Arg Val Leu Glu 210 215 220 Gln Ile Val Glu Ile Ala Arg Glu His Asp Leu Leu Ile Leu Ala Asp 225 230 235 240 Glu Ile Tyr Asp Arg Ile Leu Tyr Asp Asp Ala Glu His Ile Ser Leu 245 250 255 Ala Thr Leu Ala Pro Asp Leu Leu Cys Ile Thr Tyr Asn Gly Leu Ser 260 265 270 Lys Ala Tyr Arg Val Ala Gly Tyr Arg Ala Gly Trp Met Val Leu Thr 275 280 285 Gly Pro Lys Gln Tyr Ala Arg Gly Phe Ile Glu Gly Leu Glu Leu Leu 290 295 300 Ala Gly Thr Arg Leu Cys Pro Asn Val Pro Ala Gln His Ala Ile Gln 305 310 315 320 Val Ala Leu Gly Gly Arg Gln Ser Ile Tyr Asp Leu Thr Gly Glu His 325 330 335 Gly Arg Leu Leu Glu Gln Arg Asn Met Ala Trp Thr Lys Leu Asn Glu 340 345 350 Ile Pro Gly Val Ser Cys Val Lys Pro Met Gly Ala Leu Tyr Ala Phe 355 360 365 Pro Lys Leu Asp Pro Asn Val Tyr Glu Ile His Asp Asp Thr Gln Leu 370 375 380 Met Leu Asp Leu Leu Arg Ala Glu Lys Ile Leu Met Val Gln Gly Thr 385 390 395 400 Gly Phe Asn Trp Pro His His Asp His Phe Arg Val Val Thr Leu Pro 405 410 415 Trp Ala Ser Gln Leu Glu Asn Ala Ile Glu Arg Leu Gly Asn Phe Leu 420 425 430 Ser Thr Tyr Lys Gln 435 <210> 123 <211> 1701 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1678) <223> RXA02193 <400> 123 cccccgaaaa tgtagtgggt agttccacac tgcctcttac aagtacgtag gataatccac 60 agcaccattg tgatttcctt caacttgtga gaggcagtac atg tct aag acg agc 115 Met Ser Lys Thr Ser 1 5 aac aag tct tca gca gac tca aag aat gac gca aaa gcc gaa gac att 163 Asn Lys Ser Ser Ala Asp Ser Lys Asn Asp Ala Lys Ala Glu Asp Ile 10 15 20 gtg aac ggc gag aac caa atc gcc acg aat gag tcg cag tct tca gac 211 Val Asn Gly Glu Asn Gln Ile Ala Thr Asn Glu Ser Gln Ser Ser Asp 25 30 35 agc gct gca gtt tcg gaa cgt gtc gtc gaa cca aaa acc acg gtt cag 259 Ser Ala Ala Val Ser Glu Arg Val Val Glu Pro Lys Thr Thr Val Gln 40 45 50 aaa aag ttc cga atc gaa tcg gat ctg ctt ggt gaa ctt cag atc cca 307 Lys Lys Phe Arg Ile Glu Ser Asp Leu Leu Gly Glu Leu Gln Ile Pro 55 60 65 tcc cac gca tat tac ggg gtg cac acc ctt cgt gcg gtg gac aac ttc 355 Ser His Ala Tyr Tyr Gly Val His Thr Leu Arg Ala Val Asp Asn Phe 70 75 80 85 caa atc tca cga acc acc atc aac cac gtc cca gat ttc att cgc ggc 403 Gln Ile Ser Arg Thr Thr Ile Asn His Val Pro Asp Phe Ile Arg Gly 90 95 100 atg gtc cag gtg aaa aag gcc gca gct tta gca aac cgc cga ctg cac 451 Met Val Gln Val Lys Lys Ala Ala Ala Leu Ala Asn Arg Arg Leu His 105 110 115 aca ctt cca gca caa aaa gca gaa gca att gtc tgg gct tgt gat cag 499 Thr Leu Pro Ala Gln Lys Ala Glu Ala Ile Val Trp Ala Cys Asp Gln 120 125 130 atc ctc att gag gaa cgc tgt atg gat cag ttc ccc atc gat gtg ttc 547 Ile Leu Ile Glu Glu Arg Cys Met Asp Gln Phe Pro Ile Asp Val Phe 135 140 145 cag ggt ggc gca ggt acc tca ctg aac atg aac acc aac gag gtt gtt 595 Gln Gly Gly Ala Gly Thr Ser Leu Asn Met Asn Thr Asn Glu Val Val 150 155 160 165 gcc aac ctt gca ctt gag ttc tta ggc cat gaa aag ggc gag tac cac 643 Ala Asn Leu Ala Leu Glu Phe Leu Gly His Glu Lys Gly Glu Tyr His 170 175 180 atc ctg cac ccc atg gat gat gtg aac atg tcc cag tcc acc aac gat 691 Ile Leu His Pro Met Asp Asp Val Asn Met Ser Gln Ser Thr Asn Asp 185 190 195 tcc tac cca act ggt ttc cgc ctg ggc att tac gct gga ctg cag acc 739 Ser Tyr Pro Thr Gly Phe Arg Leu Gly Ile Tyr Ala Gly Leu Gln Thr 200 205 210 ctc atc gct gaa att gat gag ctt cag gtt gcg ttc cgc cac aag ggc 787 Leu Ile Ala Glu Ile Asp Glu Leu Gln Val Ala Phe Arg His Lys Gly 215 220 225 aat gag ttt gtc gac atc atc aag atg ggc cgc acc cag ttg cag gat 835 Asn Glu Phe Val Asp Ile Ile Lys Met Gly Arg Thr Gln Leu Gln Asp 230 235 240 245 gct gtt ccc atg agc ttg ggc gaa gag ttc cga gca ttc gcg cac aac 883 Ala Val Pro Met Ser Leu Gly Glu Glu Phe Arg Ala Phe Ala His Asn 250 255 260 ctc gca gaa gag cag acc gtg ctg cgt gaa gct gcc aac cgt ctc ctc 931 Leu Ala Glu Glu Gln Thr Val Leu Arg Glu Ala Ala Asn Arg Leu Leu 265 270 275 gag gtc aat ctt ggt gca acc gca atc ggt act ggt gtg aac act cca 979 Glu Val Asn Leu Gly Ala Thr Ala Ile Gly Thr Gly Val Asn Thr Pro 280 285 290 gca ggc tac cgc cac cag gtt gtc gct gct ctg tct gag gtc acc gga 1027 Ala Gly Tyr Arg His Gln Val Val Ala Ala Leu Ser Glu Val Thr Gly 295 300 305 ctg gaa cta aag tcc gca cgt gat ctc atc gag gct acc tct gac acc 1075 Leu Glu Leu Lys Ser Ala Arg Asp Leu Ile Glu Ala Thr Ser Asp Thr 310 315 320 325 ggt gca tat gtt cat gcg cac tcc gca atc aag cgt gca gcc atg aaa 1123 Gly Ala Tyr Val His Ala His Ser Ala Ile Lys Arg Ala Ala Met Lys 330 335 340 ctg tcc aag atc tgt aac gat cta cgt ctg ctg tct tct ggt cct cgt 1171 Leu Ser Lys Ile Cys Asn Asp Leu Arg Leu Leu Ser Ser Gly Pro Arg 345 350 355 gct ggc ttg aac gaa atc aac ctg cca cca cgc cag gct ggt tcc tcc 1219 Ala Gly Leu Asn Glu Ile Asn Leu Pro Pro Arg Gln Ala Gly Ser Ser 360 365 370 atc atg cca gcc aag gtc aac cca gtg atc cca gaa gtg gtc aac cag 1267 Ile Met Pro Ala Lys Val Asn Pro Val Ile Pro Glu Val Val Asn Gln 375 380 385 gtc tgc ttc aag gtc ttc ggt aac gat ctc acc gtc acc atg gct gcg 1315 Val Cys Phe Lys Val Phe Gly Asn Asp Leu Thr Val Thr Met Ala Ala 390 395 400 405 gaa gct ggc cag ttg cag ctc aac gtc atg gag cca gtc att ggc gaa 1363 Glu Ala Gly Gln Leu Gln Leu Asn Val Met Glu Pro Val Ile Gly Glu 410 415 420 tcc ctc ttc cag tca ctg cgc atc ctg ggc aat gca gcc aag act ttg 1411 Ser Leu Phe Gln Ser Leu Arg Ile Leu Gly Asn Ala Ala Lys Thr Leu 425 430 435 cgt gag aag tgc gtc gta gga atc acc gcc aac gct gat gtt tgc cgt 1459 Arg Glu Lys Cys Val Val Gly Ile Thr Ala Asn Ala Asp Val Cys Arg 440 445 450 gct tac gtt gat aac tcc atc ggg att atc act tac ctg aac cca ttc 1507 Ala Tyr Val Asp Asn Ser Ile Gly Ile Ile Thr Tyr Leu Asn Pro Phe 455 460 465 ctg ggc cac gac att gga gat cag atc ggt aag gaa gca gcc gaa act 1555 Leu Gly His Asp Ile Gly Asp Gln Ile Gly Lys Glu Ala Ala Glu Thr 470 475 480 485 ggt cga cca gtg cgt gaa ctc atc ctg gaa aag aag ctc atg gat gaa 1603 Gly Arg Pro Val Arg Glu Leu Ile Leu Glu Lys Lys Leu Met Asp Glu 490 495 500 aag acg ctc gag gca gtc ctg tcc aag gag aac ctc atg cac cca atg 1651 Lys Thr Leu Glu Ala Val Leu Ser Lys Glu Asn Leu Met His Pro Met 505 510 515 ttc cgc gga agg ctc tac ttg gag aac taatccaaga tctcgtctga 1698 Phe Arg Gly Arg Leu Tyr Leu Glu Asn 520 525 tac 1701 <210> 124 <211> 526 <212> PRT <213> Corynebacterium glutamicum <400> 124 Met Ser Lys Thr Ser Asn Lys Ser Ser Ala Asp Ser Lys Asn Asp Ala 1 5 10 15 Lys Ala Glu Asp Ile Val Asn Gly Glu Asn Gln Ile Ala Thr Asn Glu 20 25 30 Ser Gln Ser Ser Asp Ser Ala Ala Val Ser Glu Arg Val Val Glu Pro 35 40 45 Lys Thr Thr Val Gln Lys Lys Phe Arg Ile Glu Ser Asp Leu Leu Gly 50 55 60 Glu Leu Gln Ile Pro Ser His Ala Tyr Tyr Gly Val His Thr Leu Arg 65 70 75 80 Ala Val Asp Asn Phe Gln Ile Ser Arg Thr Thr Ile Asn His Val Pro 85 90 95 Asp Phe Ile Arg Gly Met Val Gln Val Lys Lys Ala Ala Ala Leu Ala 100 105 110 Asn Arg Arg Leu His Thr Leu Pro Ala Gln Lys Ala Glu Ala Ile Val 115 120 125 Trp Ala Cys Asp Gln Ile Leu Ile Glu Glu Arg Cys Met Asp Gln Phe 130 135 140 Pro Ile Asp Val Phe Gln Gly Gly Ala Gly Thr Ser Leu Asn Met Asn 145 150 155 160 Thr Asn Glu Val Val Ala Asn Leu Ala Leu Glu Phe Leu Gly His Glu 165 170 175 Lys Gly Glu Tyr His Ile Leu His Pro Met Asp Asp Val Asn Met Ser 180 185 190 Gln Ser Thr Asn Asp Ser Tyr Pro Thr Gly Phe Arg Leu Gly Ile Tyr 195 200 205 Ala Gly Leu Gln Thr Leu Ile Ala Glu Ile Asp Glu Leu Gln Val Ala 210 215 220 Phe Arg His Lys Gly Asn Glu Phe Val Asp Ile Ile Lys Met Gly Arg 225 230 235 240 Thr Gln Leu Gln Asp Ala Val Pro Met Ser Leu Gly Glu Glu Phe Arg 245 250 255 Ala Phe Ala His Asn Leu Ala Glu Glu Gln Thr Val Leu Arg Glu Ala 260 265 270 Ala Asn Arg Leu Leu Glu Val Asn Leu Gly Ala Thr Ala Ile Gly Thr 275 280 285 Gly Val Asn Thr Pro Ala Gly Tyr Arg His Gln Val Val Ala Ala Leu 290 295 300 Ser Glu Val Thr Gly Leu Glu Leu Lys Ser Ala Arg Asp Leu Ile Glu 305 310 315 320 Ala Thr Ser Asp Thr Gly Ala Tyr Val His Ala His Ser Ala Ile Lys 325 330 335 Arg Ala Ala Met Lys Leu Ser Lys Ile Cys Asn Asp Leu Arg Leu Leu 340 345 350 Ser Ser Gly Pro Arg Ala Gly Leu Asn Glu Ile Asn Leu Pro Pro Arg 355 360 365 Gln Ala Gly Ser Ser Ile Met Pro Ala Lys Val Asn Pro Val Ile Pro 370 375 380 Glu Val Val Asn Gln Val Cys Phe Lys Val Phe Gly Asn Asp Leu Thr 385 390 395 400 Val Thr Met Ala Ala Glu Ala Gly Gln Leu Gln Leu Asn Val Met Glu 405 410 415 Pro Val Ile Gly Glu Ser Leu Phe Gln Ser Leu Arg Ile Leu Gly Asn 420 425 430 Ala Ala Lys Thr Leu Arg Glu Lys Cys Val Val Gly Ile Thr Ala Asn 435 440 445 Ala Asp Val Cys Arg Ala Tyr Val Asp Asn Ser Ile Gly Ile Ile Thr 450 455 460 Tyr Leu Asn Pro Phe Leu Gly His Asp Ile Gly Asp Gln Ile Gly Lys 465 470 475 480 Glu Ala Ala Glu Thr Gly Arg Pro Val Arg Glu Leu Ile Leu Glu Lys 485 490 495 Lys Leu Met Asp Glu Lys Thr Leu Glu Ala Val Leu Ser Lys Glu Asn 500 505 510 Leu Met His Pro Met Phe Arg Gly Arg Leu Tyr Leu Glu Asn 515 520 525 <210> 125 <211> 1098 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1075) <223> RXA02432 <400> 125 cacgtgattc atttgtgacc aacaaccgaa actgagccag aagactgtca atcccctgct 60 gtgcacataa caactgcagc tagttgatac gctagagcgc atg tcg aag cag cac 115 Met Ser Lys Gln His 1 5 tcc aca cca tta aac aat gat gaa gaa cac act tcc gct cct caa aag 163 Ser Thr Pro Leu Asn Asn Asp Glu Glu His Thr Ser Ala Pro Gln Lys 10 15 20 gtt gcg gta atc acc acg ggc gga acc atc gcc tgt act tcc gac gca 211 Val Ala Val Ile Thr Thr Gly Gly Thr Ile Ala Cys Thr Ser Asp Ala 25 30 35 aat ggg cat ctg ctt ccc acc gtc agc ggt gca gac ctg ctt gcg cca 259 Asn Gly His Leu Leu Pro Thr Val Ser Gly Ala Asp Leu Leu Ala Pro 40 45 50 atc gca cca cgg ttc aat gga gcg cag atc gct ttc gaa atc cac gaa 307 Ile Ala Pro Arg Phe Asn Gly Ala Gln Ile Ala Phe Glu Ile His Glu 55 60 65 atc aac cgc ctt gat tcc tcc tcc atg acg ttt gag gat ctc gat tcc 355 Ile Asn Arg Leu Asp Ser Ser Ser Met Thr Phe Glu Asp Leu Asp Ser 70 75 80 85 atc atc gcc acg gtt cat aag gtg ttg gag gat ccg gat gtt gtt ggc 403 Ile Ile Ala Thr Val His Lys Val Leu Glu Asp Pro Asp Val Val Gly 90 95 100 gta gta gtt acc cac ggc acc gat tcc atg gaa gag tcc gcc atc gcc 451 Val Val Val Thr His Gly Thr Asp Ser Met Glu Glu Ser Ala Ile Ala 105 110 115 gta gac acc ttc ctt gat gat ccc cgc cca gtc att ttc acc ggc gcc 499 Val Asp Thr Phe Leu Asp Asp Pro Arg Pro Val Ile Phe Thr Gly Ala 120 125 130 caa aaa ccc ttc gat cat ccc gaa gcc gac ggc cca aac aac ctt ttc 547 Gln Lys Pro Phe Asp His Pro Glu Ala Asp Gly Pro Asn Asn Leu Phe 135 140 145 gaa gcc tgc ctc atc gca tcc gac ccc tcc gct cgc gga att ggt gca 595 Glu Ala Cys Leu Ile Ala Ser Asp Pro Ser Ala Arg Gly Ile Gly Ala 150 155 160 165 ctc att gtc ttc ggt cac gcc gtc atc cct gct cgc ggc tgc gtt aaa 643 Leu Ile Val Phe Gly His Ala Val Ile Pro Ala Arg Gly Cys Val Lys 170 175 180 tgg cac acc tct gat gag ctg gcg ttt gca acc aac ggc cct gaa gaa 691 Trp His Thr Ser Asp Glu Leu Ala Phe Ala Thr Asn Gly Pro Glu Glu 185 190 195 cca gag cgc ccc gat gcg ctg ccc gta gct aaa ttg gcg gat gtc tct 739 Pro Glu Arg Pro Asp Ala Leu Pro Val Ala Lys Leu Ala Asp Val Ser 200 205 210 gtc gaa atc atc ccc gca tac cct ggt gcc acc ggc gca atg gtg gaa 787 Val Glu Ile Ile Pro Ala Tyr Pro Gly Ala Thr Gly Ala Met Val Glu 215 220 225 gct gcc atc gct gcc ggt gct caa gga ctt gta gtg gaa gca atg gga 835 Ala Ala Ile Ala Ala Gly Ala Gln Gly Leu Val Val Glu Ala Met Gly 230 235 240 245 tca ggc aat gtt ggt tcc cgc atg ggt gat gcc cta ggt aaa gca ctt 883 Ser Gly Asn Val Gly Ser Arg Met Gly Asp Ala Leu Gly Lys Ala Leu 250 255 260 gac gct gga att ccc gtg gtg atg agc act agg gtt cct cgt ggt gaa 931 Asp Ala Gly Ile Pro Val Val Met Ser Thr Arg Val Pro Arg Gly Glu 265 270 275 gta tcc gga gtg tat ggc ggt gca ggt gga ggt gcg act ttg gct gcg 979 Val Ser Gly Val Tyr Gly Gly Ala Gly Gly Gly Ala Thr Leu Ala Ala 280 285 290 aag ggc gct gtg gga tct cgc tac ttc aga gct ggt cag gca cgt att 1027 Lys Gly Ala Val Gly Ser Arg Tyr Phe Arg Ala Gly Gln Ala Arg Ile 295 300 305 ttg ctc gcg att gcc att gcg acg ggc gca cat ccg gtg acg ctt tac 1075 Leu Leu Ala Ile Ala Ile Ala Thr Gly Ala His Pro Val Thr Leu Tyr 310 315 320 325 taatttcgcc cttggtcttg cat 1098 <210> 126 <211> 325 <212> PRT <213> Corynebacterium glutamicum <400> 126 Met Ser Lys Gln His Ser Thr Pro Leu Asn Asn Asp Glu Glu His Thr 1 5 10 15 Ser Ala Pro Gln Lys Val Ala Val Ile Thr Thr Gly Gly Thr Ile Ala 20 25 30 Cys Thr Ser Asp Ala Asn Gly His Leu Leu Pro Thr Val Ser Gly Ala 35 40 45 Asp Leu Leu Ala Pro Ile Ala Pro Arg Phe Asn Gly Ala Gln Ile Ala 50 55 60 Phe Glu Ile His Glu Ile Asn Arg Leu Asp Ser Ser Ser Met Thr Phe 65 70 75 80 Glu Asp Leu Asp Ser Ile Ile Ala Thr Val His Lys Val Leu Glu Asp 85 90 95 Pro Asp Val Val Gly Val Val Val Thr His Gly Thr Asp Ser Met Glu 100 105 110 Glu Ser Ala Ile Ala Val Asp Thr Phe Leu Asp Asp Pro Arg Pro Val 115 120 125 Ile Phe Thr Gly Ala Gln Lys Pro Phe Asp His Pro Glu Ala Asp Gly 130 135 140 Pro Asn Asn Leu Phe Glu Ala Cys Leu Ile Ala Ser Asp Pro Ser Ala 145 150 155 160 Arg Gly Ile Gly Ala Leu Ile Val Phe Gly His Ala Val Ile Pro Ala 165 170 175 Arg Gly Cys Val Lys Trp His Thr Ser Asp Glu Leu Ala Phe Ala Thr 180 185 190 Asn Gly Pro Glu Glu Pro Glu Arg Pro Asp Ala Leu Pro Val Ala Lys 195 200 205 Leu Ala Asp Val Ser Val Glu Ile Ile Pro Ala Tyr Pro Gly Ala Thr 210 215 220 Gly Ala Met Val Glu Ala Ala Ile Ala Ala Gly Ala Gln Gly Leu Val 225 230 235 240 Val Glu Ala Met Gly Ser Gly Asn Val Gly Ser Arg Met Gly Asp Ala 245 250 255 Leu Gly Lys Ala Leu Asp Ala Gly Ile Pro Val Val Met Ser Thr Arg 260 265 270 Val Pro Arg Gly Glu Val Ser Gly Val Tyr Gly Gly Ala Gly Gly Gly 275 280 285 Ala Thr Leu Ala Ala Lys Gly Ala Val Gly Ser Arg Tyr Phe Arg Ala 290 295 300 Gly Gln Ala Arg Ile Leu Leu Ala Ile Ala Ile Ala Thr Gly Ala His 305 310 315 320 Pro Val Thr Leu Tyr 325 <210> 127 <211> 775 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(775) <223> RXN03003 <400> 127 tcgatgatct gggctcccca ggtggtgcgg ctaagcttgg accacaagat tttgatcacc 60 caatgatcgc tgcgctgccg cctcaggcat aatctaacgc atg acc tct cgc acc 115 Met Thr Ser Arg Thr 1 5 ccg ctt gtt tct gtt ctt cct gat ttt ccg tgg gat tcg ctc gct tcc 163 Pro Leu Val Ser Val Leu Pro Asp Phe Pro Trp Asp Ser Leu Ala Ser 10 15 20 gca aaa gcc aaa gct gcg tct cac ccg gat ggg atc gtg aat ctt tct 211 Ala Lys Ala Lys Ala Ala Ser His Pro Asp Gly Ile Val Asn Leu Ser 25 30 35 gtt ggc act ccg gtt gat ccg gtc gcg ccc agc att cag atc gcg ttg 259 Val Gly Thr Pro Val Asp Pro Val Ala Pro Ser Ile Gln Ile Ala Leu 40 45 50 gca gaa gca gcg ggg ttt tcg ggt tac cct caa acc atc ggc acc ccg 307 Ala Glu Ala Ala Gly Phe Ser Gly Tyr Pro Gln Thr Ile Gly Thr Pro 55 60 65 gaa ctc cgc gca gcc atc agg ggc gcg ctt gag cgg cgc tac aac atg 355 Glu Leu Arg Ala Ala Ile Arg Gly Ala Leu Glu Arg Arg Tyr Asn Met 70 75 80 85 aca aag ctt gtc gac gcc tcc ctc ctc ccc gtc gtg ggt acc aag gag 403 Thr Lys Leu Val Asp Ala Ser Leu Leu Pro Val Val Gly Thr Lys Glu 90 95 100 gca att gcc ctt ctt cca ttc gcg ttg ggt att tcc ggc acc gtt gtc 451 Ala Ile Ala Leu Leu Pro Phe Ala Leu Gly Ile Ser Gly Thr Val Val 105 110 115 atc cca gag att gcg tac cca acc tac gaa gtc gct gtc gtg gcc gca 499 Ile Pro Glu Ile Ala Tyr Pro Thr Tyr Glu Val Ala Val Val Ala Ala 120 125 130 gga tgc acc gtg ttg cgt tct gat tcg ctg ttt aag ctc ggc ccg cag 547 Gly Cys Thr Val Leu Arg Ser Asp Ser Leu Phe Lys Leu Gly Pro Gln 135 140 145 atc ccg tcg atg atg ttt atc aac tca cca tcc aac ccc aca ggc aag 595 Ile Pro Ser Met Met Phe Ile Asn Ser Pro Ser Asn Pro Thr Gly Lys 150 155 160 165 gtt ctg ggc atc cca cac ttg cgc aag gtt gtg aag tgg gcg cag gaa 643 Val Leu Gly Ile Pro His Leu Arg Lys Val Val Lys Trp Ala Gln Glu 170 175 180 aac aac gtg atc ctc gca gct gat gaa tgc tac ttg ggt ctt ggc tgg 691 Asn Asn Val Ile Leu Ala Ala Asp Glu Cys Tyr Leu Gly Leu Gly Trp 185 190 195 gac gat gaa aac cca ccg atc tca att ttg gat cca cgt gtc tgc gat 739 Asp Asp Glu Asn Pro Pro Ile Ser Ile Leu Asp Pro Arg Val Cys Asp 200 205 210 ggc gac cac acc aac ttg atc gcc att cac tcg ctg 775 Gly Asp His Thr Asn Leu Ile Ala Ile His Ser Leu 215 220 225 <210> 128 <211> 225 <212> PRT <213> Corynebacterium glutamicum <400> 128 Met Thr Ser Arg Thr Pro Leu Val Ser Val Leu Pro Asp Phe Pro Trp 1 5 10 15 Asp Ser Leu Ala Ser Ala Lys Ala Lys Ala Ala Ser His Pro Asp Gly 20 25 30 Ile Val Asn Leu Ser Val Gly Thr Pro Val Asp Pro Val Ala Pro Ser 35 40 45 Ile Gln Ile Ala Leu Ala Glu Ala Ala Gly Phe Ser Gly Tyr Pro Gln 50 55 60 Thr Ile Gly Thr Pro Glu Leu Arg Ala Ala Ile Arg Gly Ala Leu Glu 65 70 75 80 Arg Arg Tyr Asn Met Thr Lys Leu Val Asp Ala Ser Leu Leu Pro Val 85 90 95 Val Gly Thr Lys Glu Ala Ile Ala Leu Leu Pro Phe Ala Leu Gly Ile 100 105 110 Ser Gly Thr Val Val Ile Pro Glu Ile Ala Tyr Pro Thr Tyr Glu Val 115 120 125 Ala Val Val Ala Ala Gly Cys Thr Val Leu Arg Ser Asp Ser Leu Phe 130 135 140 Lys Leu Gly Pro Gln Ile Pro Ser Met Met Phe Ile Asn Ser Pro Ser 145 150 155 160 Asn Pro Thr Gly Lys Val Leu Gly Ile Pro His Leu Arg Lys Val Val 165 170 175 Lys Trp Ala Gln Glu Asn Asn Val Ile Leu Ala Ala Asp Glu Cys Tyr 180 185 190 Leu Gly Leu Gly Trp Asp Asp Glu Asn Pro Pro Ile Ser Ile Leu Asp 195 200 205 Pro Arg Val Cys Asp Gly Asp His Thr Asn Leu Ile Ala Ile His Ser 210 215 220 Leu 225 <210> 129 <211> 1206 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1183) <223> RXN00508 <400> 129 agccacgtgt ttaaggatag ttgaaagcgt ggggcaatac tggcactaac cccggcacca 60 atcgtatttc tgtccgcggt tggtggcaca atagttcaac atg aac ttg ctg acc 115 Met Asn Leu Leu Thr 1 5 acc aaa att gac ctg gat gcc atc gcc cat aac acg agg gtg ctt aaa 163 Thr Lys Ile Asp Leu Asp Ala Ile Ala His Asn Thr Arg Val Leu Lys 10 15 20 caa atg gcg ggt ccg gcg aag ctg atg gcg gtg gtg aag gcg aat gca 211 Gln Met Ala Gly Pro Ala Lys Leu Met Ala Val Val Lys Ala Asn Ala 25 30 35 tat aac cat ggc gta gag aag gtc gct ccg gtt att gct gct cat ggt 259 Tyr Asn His Gly Val Glu Lys Val Ala Pro Val Ile Ala Ala His Gly 40 45 50 gcg gat gcg ttt ggt gtg gca act ctt gcg gag gct atg cag ttg cgt 307 Ala Asp Ala Phe Gly Val Ala Thr Leu Ala Glu Ala Met Gln Leu Arg 55 60 65 gat atc ggc atc agc caa gag gtt ttg tgt tgg att tgg aca ccg gag 355 Asp Ile Gly Ile Ser Gln Glu Val Leu Cys Trp Ile Trp Thr Pro Glu 70 75 80 85 cag gat ttc cgc gcc gcc att gat cgc aat att gat ttg gct gtt att 403 Gln Asp Phe Arg Ala Ala Ile Asp Arg Asn Ile Asp Leu Ala Val Ile 90 95 100 tct ccc gcg cat gcc aaa gcc ttg atc gaa act gat gcg gag cat att 451 Ser Pro Ala His Ala Lys Ala Leu Ile Glu Thr Asp Ala Glu His Ile 105 110 115 cgg gtg tcc atc aag att gat tct ggg ttg cat cgt tcg ggt gtg gat 499 Arg Val Ser Ile Lys Ile Asp Ser Gly Leu His Arg Ser Gly Val Asp 120 125 130 gag cag gag tgg gag ggc gtg ttc agc gcg ttg gct gct gcc ccg cac 547 Glu Gln Glu Trp Glu Gly Val Phe Ser Ala Leu Ala Ala Ala Pro His 135 140 145 att gag gtc acg ggc atg ttc acg cac ttg gcg tgc gcg gat gag cca 595 Ile Glu Val Thr Gly Met Phe Thr His Leu Ala Cys Ala Asp Glu Pro 150 155 160 165 gag aat ccg gaa act gat cgc caa att att gct ttt cga cgc gcc ctt 643 Glu Asn Pro Glu Thr Asp Arg Gln Ile Ile Ala Phe Arg Arg Ala Leu 170 175 180 gcg ctc gcc cgc aag cac ggg ctt gag tgc ccg gtc aac cac gta tgc 691 Ala Leu Ala Arg Lys His Gly Leu Glu Cys Pro Val Asn His Val Cys 185 190 195 aac tca cct gca ttc ttg act cga tct gat tta cac atg gag atg gtc 739 Asn Ser Pro Ala Phe Leu Thr Arg Ser Asp Leu His Met Glu Met Val 200 205 210 cga ccg ggt ttg gcc ttt tat ggg ttg gaa ccc gtg gcg gga ctg gag 787 Arg Pro Gly Leu Ala Phe Tyr Gly Leu Glu Pro Val Ala Gly Leu Glu 215 220 225 cat ggt ttg aag ccg gcg atg acg tgg gag gcg aag gtg agc gtc gta 835 His Gly Leu Lys Pro Ala Met Thr Trp Glu Ala Lys Val Ser Val Val 230 235 240 245 aag caa att gaa gct gga caa ggc act tcc tat ggc ctg acc tgg cgc 883 Lys Gln Ile Glu Ala Gly Gln Gly Thr Ser Tyr Gly Leu Thr Trp Arg 250 255 260 gct gag gat cgc ggc ttt gtg gct gtg gtg cct gcg ggc tat gcc gat 931 Ala Glu Asp Arg Gly Phe Val Ala Val Val Pro Ala Gly Tyr Ala Asp 265 270 275 ggc atg ccg cgg cat gcc cag ggg aaa ttc tcc gtc acg att gat ggc 979 Gly Met Pro Arg His Ala Gln Gly Lys Phe Ser Val Thr Ile Asp Gly 280 285 290 ctg gac tat ccg cag gtt ggg cgc gta tgc atg gat cag ttc gtt att 1027 Leu Asp Tyr Pro Gln Val Gly Arg Val Cys Met Asp Gln Phe Val Ile 295 300 305 tct ttg ggc gac aat cca cac ggc gtg gaa gct ggg gcg aag gcc gtg 1075 Ser Leu Gly Asp Asn Pro His Gly Val Glu Ala Gly Ala Lys Ala Val 310 315 320 325 ata ttc ggt gag aat ggg cat gac gca act gat ttt gcg gag cgt tta 1123 Ile Phe Gly Glu Asn Gly His Asp Ala Thr Asp Phe Ala Glu Arg Leu 330 335 340 gac acc att aac tat gag gta gtg tgc cga cca acc ggc cga act gtc 1171 Asp Thr Ile Asn Tyr Glu Val Val Cys Arg Pro Thr Gly Arg Thr Val 345 350 355 cgc gca tat gtt taagtgaata cgtttaagga gca 1206 Arg Ala Tyr Val 360 <210> 130 <211> 361 <212> PRT <213> Corynebacterium glutamicum <400> 130 Met Asn Leu Leu Thr Thr Lys Ile Asp Leu Asp Ala Ile Ala His Asn 1 5 10 15 Thr Arg Val Leu Lys Gln Met Ala Gly Pro Ala Lys Leu Met Ala Val 20 25 30 Val Lys Ala Asn Ala Tyr Asn His Gly Val Glu Lys Val Ala Pro Val 35 40 45 Ile Ala Ala His Gly Ala Asp Ala Phe Gly Val Ala Thr Leu Ala Glu 50 55 60 Ala Met Gln Leu Arg Asp Ile Gly Ile Ser Gln Glu Val Leu Cys Trp 65 70 75 80 Ile Trp Thr Pro Glu Gln Asp Phe Arg Ala Ala Ile Asp Arg Asn Ile 85 90 95 Asp Leu Ala Val Ile Ser Pro Ala His Ala Lys Ala Leu Ile Glu Thr 100 105 110 Asp Ala Glu His Ile Arg Val Ser Ile Lys Ile Asp Ser Gly Leu His 115 120 125 Arg Ser Gly Val Asp Glu Gln Glu Trp Glu Gly Val Phe Ser Ala Leu 130 135 140 Ala Ala Ala Pro His Ile Glu Val Thr Gly Met Phe Thr His Leu Ala 145 150 155 160 Cys Ala Asp Glu Pro Glu Asn Pro Glu Thr Asp Arg Gln Ile Ile Ala 165 170 175 Phe Arg Arg Ala Leu Ala Leu Ala Arg Lys His Gly Leu Glu Cys Pro 180 185 190 Val Asn His Val Cys Asn Ser Pro Ala Phe Leu Thr Arg Ser Asp Leu 195 200 205 His Met Glu Met Val Arg Pro Gly Leu Ala Phe Tyr Gly Leu Glu Pro 210 215 220 Val Ala Gly Leu Glu His Gly Leu Lys Pro Ala Met Thr Trp Glu Ala 225 230 235 240 Lys Val Ser Val Val Lys Gln Ile Glu Ala Gly Gln Gly Thr Ser Tyr 245 250 255 Gly Leu Thr Trp Arg Ala Glu Asp Arg Gly Phe Val Ala Val Val Pro 260 265 270 Ala Gly Tyr Ala Asp Gly Met Pro Arg His Ala Gln Gly Lys Phe Ser 275 280 285 Val Thr Ile Asp Gly Leu Asp Tyr Pro Gln Val Gly Arg Val Cys Met 290 295 300 Asp Gln Phe Val Ile Ser Leu Gly Asp Asn Pro His Gly Val Glu Ala 305 310 315 320 Gly Ala Lys Ala Val Ile Phe Gly Glu Asn Gly His Asp Ala Thr Asp 325 330 335 Phe Ala Glu Arg Leu Asp Thr Ile Asn Tyr Glu Val Val Cys Arg Pro 340 345 350 Thr Gly Arg Thr Val Arg Ala Tyr Val 355 360 <210> 131 <211> 1152 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1129) <223> RXN00636 <400> 131 tcatgggatt cagcaaggcg gccacccgaa ccgtctttgg tggaggagta ggagcgatga 60 tcgatctggc ccgttcgaac ataaggaata ttcctactcc atg atg att gat aca 115 Met Met Ile Asp Thr 1 5 cct gct gtt ctc att gac cgc gag cgc tta act gcc aac att tcc agg 163 Pro Ala Val Leu Ile Asp Arg Glu Arg Leu Thr Ala Asn Ile Ser Arg 10 15 20 atg gca gct cac gcc ggt gcc cat gag att gcc ctg cgt ccg cat gtg 211 Met Ala Ala His Ala Gly Ala His Glu Ile Ala Leu Arg Pro His Val 25 30 35 aaa acg cac aaa atc att gaa att gcg cag atg cag gtc gac gcc ggt 259 Lys Thr His Lys Ile Ile Glu Ile Ala Gln Met Gln Val Asp Ala Gly 40 45 50 gcc cga ggg atc acc tgc gca acc att ggc gag gcg gaa att ttt gcc 307 Ala Arg Gly Ile Thr Cys Ala Thr Ile Gly Glu Ala Glu Ile Phe Ala 55 60 65 ggc gca ggt ttt acg gac atc ttt att gca tat ccg ctg tat cta acc 355 Gly Ala Gly Phe Thr Asp Ile Phe Ile Ala Tyr Pro Leu Tyr Leu Thr 70 75 80 85 gat cat gca gtg caa cgc ctg aac gcg atc ccc gga gaa att tcc att 403 Asp His Ala Val Gln Arg Leu Asn Ala Ile Pro Gly Glu Ile Ser Ile 90 95 100 ggc gtg gat tcg gta gag atg gca cag gcg acg gcg ggt ttg cgg gaa 451 Gly Val Asp Ser Val Glu Met Ala Gln Ala Thr Ala Gly Leu Arg Glu 105 110 115 gat atc aag gct ctg att gaa gtg gat tcg gga cat cgt aga agt gga 499 Asp Ile Lys Ala Leu Ile Glu Val Asp Ser Gly His Arg Arg Ser Gly 120 125 130 gtc acg gcg act gct tca gaa ttg agt cag atc cgc gag gcg ctg ggc 547 Val Thr Ala Thr Ala Ser Glu Leu Ser Gln Ile Arg Glu Ala Leu Gly 135 140 145 agc agg tat gca gga gtg ttt act ttt cct ggg cat tct tat ggc ccg 595 Ser Arg Tyr Ala Gly Val Phe Thr Phe Pro Gly His Ser Tyr Gly Pro 150 155 160 165 gga aat ggt gag cag gca gca gct gat gag ctt cag gct cta aac aac 643 Gly Asn Gly Glu Gln Ala Ala Ala Asp Glu Leu Gln Ala Leu Asn Asn 170 175 180 agc gtc cag cga ctt gct ggc ggc ctg act tct ggc ggt tcc tcg ccg 691 Ser Val Gln Arg Leu Ala Gly Gly Leu Thr Ser Gly Gly Ser Ser Pro 185 190 195 tct gcg cag ttt aca gac gca atc gat gag atg cga cca ggc gtg tat 739 Ser Ala Gln Phe Thr Asp Ala Ile Asp Glu Met Arg Pro Gly Val Tyr 200 205 210 gtg ttt aac gat tcc cag cag atc acc tcg gga gca tgc act gag aag 787 Val Phe Asn Asp Ser Gln Gln Ile Thr Ser Gly Ala Cys Thr Glu Lys 215 220 225 cag gtg gca atg acg gtg ctg tct act gtg gtc agc cga aat gtg tca 835 Gln Val Ala Met Thr Val Leu Ser Thr Val Val Ser Arg Asn Val Ser 230 235 240 245 gat cgt cgg atc att ttg gat gcg gga tcc aaa atc ctc agc act gat 883 Asp Arg Arg Ile Ile Leu Asp Ala Gly Ser Lys Ile Leu Ser Thr Asp 250 255 260 aaa cca gca tgg att gat ggc aat ggt ttt gtt ctg ggg aat cct gaa 931 Lys Pro Ala Trp Ile Asp Gly Asn Gly Phe Val Leu Gly Asn Pro Glu 265 270 275 gcc cga atc tct gct ttg tcg gag cat cac gca acc att ttc tgg cca 979 Ala Arg Ile Ser Ala Leu Ser Glu His His Ala Thr Ile Phe Trp Pro 280 285 290 gat aaa gtg cta ctt cca gta atc ggg gag cag ctc aac atc gtg ccc 1027 Asp Lys Val Leu Leu Pro Val Ile Gly Glu Gln Leu Asn Ile Val Pro 295 300 305 aac cat gcc tgc aac gtg att aat ttg gtg gat gag gtc tac gtt cgg 1075 Asn His Ala Cys Asn Val Ile Asn Leu Val Asp Glu Val Tyr Val Arg 310 315 320 325 gaa gcc gat ggc act ttc cgt acc tgg aag gta gtt gcc cgc ggc aga 1123 Glu Ala Asp Gly Thr Phe Arg Thr Trp Lys Val Val Ala Arg Gly Arg 330 335 340 aac aat tagggaaacc tcttgacctt cac 1152 Asn Asn <210> 132 <211> 343 <212> PRT <213> Corynebacterium glutamicum <400> 132 Met Met Ile Asp Thr Pro Ala Val Leu Ile Asp Arg Glu Arg Leu Thr 1 5 10 15 Ala Asn Ile Ser Arg Met Ala Ala His Ala Gly Ala His Glu Ile Ala 20 25 30 Leu Arg Pro His Val Lys Thr His Lys Ile Ile Glu Ile Ala Gln Met 35 40 45 Gln Val Asp Ala Gly Ala Arg Gly Ile Thr Cys Ala Thr Ile Gly Glu 50 55 60 Ala Glu Ile Phe Ala Gly Ala Gly Phe Thr Asp Ile Phe Ile Ala Tyr 65 70 75 80 Pro Leu Tyr Leu Thr Asp His Ala Val Gln Arg Leu Asn Ala Ile Pro 85 90 95 Gly Glu Ile Ser Ile Gly Val Asp Ser Val Glu Met Ala Gln Ala Thr 100 105 110 Ala Gly Leu Arg Glu Asp Ile Lys Ala Leu Ile Glu Val Asp Ser Gly 115 120 125 His Arg Arg Ser Gly Val Thr Ala Thr Ala Ser Glu Leu Ser Gln Ile 130 135 140 Arg Glu Ala Leu Gly Ser Arg Tyr Ala Gly Val Phe Thr Phe Pro Gly 145 150 155 160 His Ser Tyr Gly Pro Gly Asn Gly Glu Gln Ala Ala Ala Asp Glu Leu 165 170 175 Gln Ala Leu Asn Asn Ser Val Gln Arg Leu Ala Gly Gly Leu Thr Ser 180 185 190 Gly Gly Ser Ser Pro Ser Ala Gln Phe Thr Asp Ala Ile Asp Glu Met 195 200 205 Arg Pro Gly Val Tyr Val Phe Asn Asp Ser Gln Gln Ile Thr Ser Gly 210 215 220 Ala Cys Thr Glu Lys Gln Val Ala Met Thr Val Leu Ser Thr Val Val 225 230 235 240 Ser Arg Asn Val Ser Asp Arg Arg Ile Ile Leu Asp Ala Gly Ser Lys 245 250 255 Ile Leu Ser Thr Asp Lys Pro Ala Trp Ile Asp Gly Asn Gly Phe Val 260 265 270 Leu Gly Asn Pro Glu Ala Arg Ile Ser Ala Leu Ser Glu His His Ala 275 280 285 Thr Ile Phe Trp Pro Asp Lys Val Leu Leu Pro Val Ile Gly Glu Gln 290 295 300 Leu Asn Ile Val Pro Asn His Ala Cys Asn Val Ile Asn Leu Val Asp 305 310 315 320 Glu Val Tyr Val Arg Glu Ala Asp Gly Thr Phe Arg Thr Trp Lys Val 325 330 335 Val Ala Arg Gly Arg Asn Asn 340 <210> 133 <211> 879 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(856) <223> RXA02536 <400> 133 aagaagtgat cacgcgaacc tgtgtataac ttgcctcaaa gcgcctaggc tgtggattat 60 gcgtattgcc ttgcttcaga tctcgacgaa ttccgataag atg gac aac ttc gcc 115 Met Asp Asn Phe Ala 1 5 ctg ctg cgt gat gct gct gaa aaa gct gcg gaa cag ggg gct cgg gtg 163 Leu Leu Arg Asp Ala Ala Glu Lys Ala Ala Glu Gln Gly Ala Arg Val 10 15 20 ttg gtg ttt ccg gag gcg act tcg caa agc ttt ggt acg gga agg ctt 211 Leu Val Phe Pro Glu Ala Thr Ser Gln Ser Phe Gly Thr Gly Arg Leu 25 30 35 gat act cag gcg gag gag ctc gat ggc gaa ttc tcc acc gcg gta cga 259 Asp Thr Gln Ala Glu Glu Leu Asp Gly Glu Phe Ser Thr Ala Val Arg 40 45 50 aaa tta gcc gat gag ctg gac gtt gtc atc gtt gcg ggc atg ttc acc 307 Lys Leu Ala Asp Glu Leu Asp Val Val Ile Val Ala Gly Met Phe Thr 55 60 65 cct gct gac acc gtg cag cgc ggt gaa aaa acg atc tcg cgc gtc aac 355 Pro Ala Asp Thr Val Gln Arg Gly Glu Lys Thr Ile Ser Arg Val Asn 70 75 80 85 aac acc gtg ctg att agt ggc gct gga ttg cat cag gga tac aac aaa 403 Asn Thr Val Leu Ile Ser Gly Ala Gly Leu His Gln Gly Tyr Asn Lys 90 95 100 att cac aca tat gac gcg ttc ggt tat agg gaa tcc gac act gtg aaa 451 Ile His Thr Tyr Asp Ala Phe Gly Tyr Arg Glu Ser Asp Thr Val Lys 105 110 115 ccg ggc gat gag ctg gtt gta ttc gag gtc gac gat att aaa ttt ggt 499 Pro Gly Asp Glu Leu Val Val Phe Glu Val Asp Asp Ile Lys Phe Gly 120 125 130 gtg gcg aca tgc tac gat att cga ttc cca gaa cag ttc aaa gac ctc 547 Val Ala Thr Cys Tyr Asp Ile Arg Phe Pro Glu Gln Phe Lys Asp Leu 135 140 145 gcc cgc aac ggt gca cag ata att gtg gtt ccc acg tcg tgg caa gac 595 Ala Arg Asn Gly Ala Gln Ile Ile Val Val Pro Thr Ser Trp Gln Asp 150 155 160 165 ggt cct gga aaa tta gaa caa tgg gaa gtc ctc cct cgc gcg cgt gca 643 Gly Pro Gly Lys Leu Glu Gln Trp Glu Val Leu Pro Arg Ala Arg Ala 170 175 180 ctg gat tcc acc tgc tgg atc gta gcg tgt ggg caa gcg cga ctt cca 691 Leu Asp Ser Thr Cys Trp Ile Val Ala Cys Gly Gln Ala Arg Leu Pro 185 190 195 gaa gaa tta cgc gat gaa cga aaa ggc cct acg ggg att ggt cat tcc 739 Glu Glu Leu Arg Asp Glu Arg Lys Gly Pro Thr Gly Ile Gly His Ser 200 205 210 atg gtg aca aac cca cac ggt gaa gta att gct agc gcg ggt tat gag 787 Met Val Thr Asn Pro His Gly Glu Val Ile Ala Ser Ala Gly Tyr Glu 215 220 225 cca gaa atg ttg atc gcg gat att gat gtc agc ggt ttg gcc aaa att 835 Pro Glu Met Leu Ile Ala Asp Ile Asp Val Ser Gly Leu Ala Lys Ile 230 235 240 245 cgg gag gca ttg cct gtt ctt taaccactgt ctaaggaatc act 879 Arg Glu Ala Leu Pro Val Leu 250 <210> 134 <211> 252 <212> PRT <213> Corynebacterium glutamicum <400> 134 Met Asp Asn Phe Ala Leu Leu Arg Asp Ala Ala Glu Lys Ala Ala Glu 1 5 10 15 Gln Gly Ala Arg Val Leu Val Phe Pro Glu Ala Thr Ser Gln Ser Phe 20 25 30 Gly Thr Gly Arg Leu Asp Thr Gln Ala Glu Glu Leu Asp Gly Glu Phe 35 40 45 Ser Thr Ala Val Arg Lys Leu Ala Asp Glu Leu Asp Val Val Ile Val 50 55 60 Ala Gly Met Phe Thr Pro Ala Asp Thr Val Gln Arg Gly Glu Lys Thr 65 70 75 80 Ile Ser Arg Val Asn Asn Thr Val Leu Ile Ser Gly Ala Gly Leu His 85 90 95 Gln Gly Tyr Asn Lys Ile His Thr Tyr Asp Ala Phe Gly Tyr Arg Glu 100 105 110 Ser Asp Thr Val Lys Pro Gly Asp Glu Leu Val Val Phe Glu Val Asp 115 120 125 Asp Ile Lys Phe Gly Val Ala Thr Cys Tyr Asp Ile Arg Phe Pro Glu 130 135 140 Gln Phe Lys Asp Leu Ala Arg Asn Gly Ala Gln Ile Ile Val Val Pro 145 150 155 160 Thr Ser Trp Gln Asp Gly Pro Gly Lys Leu Glu Gln Trp Glu Val Leu 165 170 175 Pro Arg Ala Arg Ala Leu Asp Ser Thr Cys Trp Ile Val Ala Cys Gly 180 185 190 Gln Ala Arg Leu Pro Glu Glu Leu Arg Asp Glu Arg Lys Gly Pro Thr 195 200 205 Gly Ile Gly His Ser Met Val Thr Asn Pro His Gly Glu Val Ile Ala 210 215 220 Ser Ala Gly Tyr Glu Pro Glu Met Leu Ile Ala Asp Ile Asp Val Ser 225 230 235 240 Gly Leu Ala Lys Ile Arg Glu Ala Leu Pro Val Leu 245 250 <210> 135 <211> 1635 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1612) <223> RXS00870 <400> 135 caagacggcg atgtcgccgc cgctgttgat accgcagcgc gacttgttca cacagatatt 60 caacaattca cttcgcagag catttaagga atttacacac atg tct gaa cca caa 115 Met Ser Glu Pro Gln 1 5 acc atc tcg cac tgg att gac ggc gcg att tcc cca tcc act tcc ggc 163 Thr Ile Ser His Trp Ile Asp Gly Ala Ile Ser Pro Ser Thr Ser Gly 10 15 20 aag acc gct cct gtc tac aat cct gca act ggc cag gtc acc gcc aat 211 Lys Thr Ala Pro Val Tyr Asn Pro Ala Thr Gly Gln Val Thr Ala Asn 25 30 35 gtt gcg ctg gct agc cag gaa gag atc gat gcc acc atc gct tct gcc 259 Val Ala Leu Ala Ser Gln Glu Glu Ile Asp Ala Thr Ile Ala Ser Ala 40 45 50 acc aag gct gct aag acg tgg ggc aac ctg tct atc gct aag cgc caa 307 Thr Lys Ala Ala Lys Thr Trp Gly Asn Leu Ser Ile Ala Lys Arg Gln 55 60 65 gct gtg ctt ttc aac ttc cgt gag ctg ctg aat gct cgc aag ggt gag 355 Ala Val Leu Phe Asn Phe Arg Glu Leu Leu Asn Ala Arg Lys Gly Glu 70 75 80 85 ctg gcg gag atc atc act gca gag cac ggc aag gtc ttg tcc gat gcc 403 Leu Ala Glu Ile Ile Thr Ala Glu His Gly Lys Val Leu Ser Asp Ala 90 95 100 atg ggt gaa atc ctg cgc ggc cag gaa gtc gtg gag ctt gct acc ggt 451 Met Gly Glu Ile Leu Arg Gly Gln Glu Val Val Glu Leu Ala Thr Gly 105 110 115 ttc cca cac ctg ctt aaa ggt gcg ttc aac gag aac gtc tcc acc ggc 499 Phe Pro His Leu Leu Lys Gly Ala Phe Asn Glu Asn Val Ser Thr Gly 120 125 130 att gat gtg tat tcc ttg aag cag cca ctg ggt gtt gtc ggt atc atc 547 Ile Asp Val Tyr Ser Leu Lys Gln Pro Leu Gly Val Val Gly Ile Ile 135 140 145 agc ccg ttc aac ttc cct gcg atg gtg ccg atg tgg ttt ttc cca atc 595 Ser Pro Phe Asn Phe Pro Ala Met Val Pro Met Trp Phe Phe Pro Ile 150 155 160 165 gca atc gct gca ggc aac gca gtt att ttg aag cct tca gag aag gat 643 Ala Ile Ala Ala Gly Asn Ala Val Ile Leu Lys Pro Ser Glu Lys Asp 170 175 180 cct tcg gca gcg ctg tgg atg gct cag atc tgg aag gaa gct ggt ctt 691 Pro Ser Ala Ala Leu Trp Met Ala Gln Ile Trp Lys Glu Ala Gly Leu 185 190 195 cca gac ggc gta ttc aac gtg ctc cag ggc gac aag ctg gct gtt gat 739 Pro Asp Gly Val Phe Asn Val Leu Gln Gly Asp Lys Leu Ala Val Asp 200 205 210 ggt ttg ctg aac agc cct gat gtc tct gcg att tcc ttc gtg ggt tcc 787 Gly Leu Leu Asn Ser Pro Asp Val Ser Ala Ile Ser Phe Val Gly Ser 215 220 225 acc cca atc gca aag tac atc tac gag act tcc gcg aag aac ggc aag 835 Thr Pro Ile Ala Lys Tyr Ile Tyr Glu Thr Ser Ala Lys Asn Gly Lys 230 235 240 245 cgc gtc cag gcg ttg ggc ggc gcg aag aac cac atg ctg gtg ctg cca 883 Arg Val Gln Ala Leu Gly Gly Ala Lys Asn His Met Leu Val Leu Pro 250 255 260 gat gct gat ctg gat ctg gtt gcc gat cag gca atc aac gca ggt tac 931 Asp Ala Asp Leu Asp Leu Val Ala Asp Gln Ala Ile Asn Ala Gly Tyr 265 270 275 ggc gct gcc ggt gag cgt tgc atg gct gtt tct gtg gtc ttg gct att 979 Gly Ala Ala Gly Glu Arg Cys Met Ala Val Ser Val Val Leu Ala Ile 280 285 290 gaa tct gtt gcc gac gag ctc att gag aag atc aag gag cgc atc gac 1027 Glu Ser Val Ala Asp Glu Leu Ile Glu Lys Ile Lys Glu Arg Ile Asp 295 300 305 acc ctg cgc atc ggc aac ggt gcc ggc gac gag cag ggc gag ccg cac 1075 Thr Leu Arg Ile Gly Asn Gly Ala Gly Asp Glu Gln Gly Glu Pro His 310 315 320 325 ctg ggc cca cta atc acc gac gtc cac cgc gac aag gtc gct tct tat 1123 Leu Gly Pro Leu Ile Thr Asp Val His Arg Asp Lys Val Ala Ser Tyr 330 335 340 gtc gac atc gct gag gcc gac ggc gcc aag atc atc gtg gac ggg cgt 1171 Val Asp Ile Ala Glu Ala Asp Gly Ala Lys Ile Ile Val Asp Gly Arg 345 350 355 aac tgc gcc gta gac ggg cac gag gag ggc ttc ttc ttc ggc cct acg 1219 Asn Cys Ala Val Asp Gly His Glu Glu Gly Phe Phe Phe Gly Pro Thr 360 365 370 ctt atc gac gac atc cca ctc acg ttc cgc gcc tac acc gaa gaa atc 1267 Leu Ile Asp Asp Ile Pro Leu Thr Phe Arg Ala Tyr Thr Glu Glu Ile 375 380 385 ttc ggc ccg gtc ctc tct gtc gtt cgt gtc gca tcc ttc gac gag gca 1315 Phe Gly Pro Val Leu Ser Val Val Arg Val Ala Ser Phe Asp Glu Ala 390 395 400 405 att gag ctg atc aac tcc ggt gaa ttc ggc aac gga acc gca atc ttc 1363 Ile Glu Leu Ile Asn Ser Gly Glu Phe Gly Asn Gly Thr Ala Ile Phe 410 415 420 acc aac gat ggt gga gcg gca cgc cgc ttc cag cat gag atc gaa gtg 1411 Thr Asn Asp Gly Gly Ala Ala Arg Arg Phe Gln His Glu Ile Glu Val 425 430 435 ggc atg atc ggc atc aac gta cca atc cca gtg cct gtt gcg tac cac 1459 Gly Met Ile Gly Ile Asn Val Pro Ile Pro Val Pro Val Ala Tyr His 440 445 450 tcc ttc ggt ggt tgg aag aac tcc ctc ttc ggt gac gcc aag gca tat 1507 Ser Phe Gly Gly Trp Lys Asn Ser Leu Phe Gly Asp Ala Lys Ala Tyr 455 460 465 ggc act caa ggt ttt gat ttc ttc acc agg gaa aag gcg atc acc agc 1555 Gly Thr Gln Gly Phe Asp Phe Phe Thr Arg Glu Lys Ala Ile Thr Ser 470 475 480 485 cgt tgg ctc gac cca gca acc cac ggt ggc att aac ctc ggt ttc cca 1603 Arg Trp Leu Asp Pro Ala Thr His Gly Gly Ile Asn Leu Gly Phe Pro 490 495 500 cag aac gat taattgaagg agagcacagg act 1635 Gln Asn Asp <210> 136 <211> 504 <212> PRT <213> Corynebacterium glutamicum <400> 136 Met Ser Glu Pro Gln Thr Ile Ser His Trp Ile Asp Gly Ala Ile Ser 1 5 10 15 Pro Ser Thr Ser Gly Lys Thr Ala Pro Val Tyr Asn Pro Ala Thr Gly 20 25 30 Gln Val Thr Ala Asn Val Ala Leu Ala Ser Gln Glu Glu Ile Asp Ala 35 40 45 Thr Ile Ala Ser Ala Thr Lys Ala Ala Lys Thr Trp Gly Asn Leu Ser 50 55 60 Ile Ala Lys Arg Gln Ala Val Leu Phe Asn Phe Arg Glu Leu Leu Asn 65 70 75 80 Ala Arg Lys Gly Glu Leu Ala Glu Ile Ile Thr Ala Glu His Gly Lys 85 90 95 Val Leu Ser Asp Ala Met Gly Glu Ile Leu Arg Gly Gln Glu Val Val 100 105 110 Glu Leu Ala Thr Gly Phe Pro His Leu Leu Lys Gly Ala Phe Asn Glu 115 120 125 Asn Val Ser Thr Gly Ile Asp Val Tyr Ser Leu Lys Gln Pro Leu Gly 130 135 140 Val Val Gly Ile Ile Ser Pro Phe Asn Phe Pro Ala Met Val Pro Met 145 150 155 160 Trp Phe Phe Pro Ile Ala Ile Ala Ala Gly Asn Ala Val Ile Leu Lys 165 170 175 Pro Ser Glu Lys Asp Pro Ser Ala Ala Leu Trp Met Ala Gln Ile Trp 180 185 190 Lys Glu Ala Gly Leu Pro Asp Gly Val Phe Asn Val Leu Gln Gly Asp 195 200 205 Lys Leu Ala Val Asp Gly Leu Leu Asn Ser Pro Asp Val Ser Ala Ile 210 215 220 Ser Phe Val Gly Ser Thr Pro Ile Ala Lys Tyr Ile Tyr Glu Thr Ser 225 230 235 240 Ala Lys Asn Gly Lys Arg Val Gln Ala Leu Gly Gly Ala Lys Asn His 245 250 255 Met Leu Val Leu Pro Asp Ala Asp Leu Asp Leu Val Ala Asp Gln Ala 260 265 270 Ile Asn Ala Gly Tyr Gly Ala Ala Gly Glu Arg Cys Met Ala Val Ser 275 280 285 Val Val Leu Ala Ile Glu Ser Val Ala Asp Glu Leu Ile Glu Lys Ile 290 295 300 Lys Glu Arg Ile Asp Thr Leu Arg Ile Gly Asn Gly Ala Gly Asp Glu 305 310 315 320 Gln Gly Glu Pro His Leu Gly Pro Leu Ile Thr Asp Val His Arg Asp 325 330 335 Lys Val Ala Ser Tyr Val Asp Ile Ala Glu Ala Asp Gly Ala Lys Ile 340 345 350 Ile Val Asp Gly Arg Asn Cys Ala Val Asp Gly His Glu Glu Gly Phe 355 360 365 Phe Phe Gly Pro Thr Leu Ile Asp Asp Ile Pro Leu Thr Phe Arg Ala 370 375 380 Tyr Thr Glu Glu Ile Phe Gly Pro Val Leu Ser Val Val Arg Val Ala 385 390 395 400 Ser Phe Asp Glu Ala Ile Glu Leu Ile Asn Ser Gly Glu Phe Gly Asn 405 410 415 Gly Thr Ala Ile Phe Thr Asn Asp Gly Gly Ala Ala Arg Arg Phe Gln 420 425 430 His Glu Ile Glu Val Gly Met Ile Gly Ile Asn Val Pro Ile Pro Val 435 440 445 Pro Val Ala Tyr His Ser Phe Gly Gly Trp Lys Asn Ser Leu Phe Gly 450 455 460 Asp Ala Lys Ala Tyr Gly Thr Gln Gly Phe Asp Phe Phe Thr Arg Glu 465 470 475 480 Lys Ala Ile Thr Ser Arg Trp Leu Asp Pro Ala Thr His Gly Gly Ile 485 490 495 Asn Leu Gly Phe Pro Gln Asn Asp 500 <210> 137 <211> 531 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(508) <223> RXS02299 <400> 137 acgcgggggt tgttgccgga tcgaaatatt cctttccttg tcatctcacg ctatgatttc 60 taaaacttgc aggacaaccc ccataaggac accacaggac atg ctg cgc acc atc 115 Met Leu Arg Thr Ile 1 5 ctc gga agt aag att cac cga gcc act gtc act caa gct gat cta gat 163 Leu Gly Ser Lys Ile His Arg Ala Thr Val Thr Gln Ala Asp Leu Asp 10 15 20 tat gtt ggc tct gta acc atc gac gcc gac ctg gtt cac gcc gcc gga 211 Tyr Val Gly Ser Val Thr Ile Asp Ala Asp Leu Val His Ala Ala Gly 25 30 35 ttg atc gaa ggc gaa aaa gtt gcc atc gta gac atc acc aac ggc gct 259 Leu Ile Glu Gly Glu Lys Val Ala Ile Val Asp Ile Thr Asn Gly Ala 40 45 50 cgt ctg gaa act tat gtc att gtg ggc gac gcc gga acg ggc aat att 307 Arg Leu Glu Thr Tyr Val Ile Val Gly Asp Ala Gly Thr Gly Asn Ile 55 60 65 tgc atc aat ggt gcc gct gca cac ctt att aat cct ggc gat ctt gtg 355 Cys Ile Asn Gly Ala Ala Ala His Leu Ile Asn Pro Gly Asp Leu Val 70 75 80 85 atc atc atg agc tac ctt cag gca act gat gcg gaa gcc aag gcg tat 403 Ile Ile Met Ser Tyr Leu Gln Ala Thr Asp Ala Glu Ala Lys Ala Tyr 90 95 100 gag cca aag att gtg cac gtg gac gcc gac aac cgc atc gtt gcg ctc 451 Glu Pro Lys Ile Val His Val Asp Ala Asp Asn Arg Ile Val Ala Leu 105 110 115 ggc aac gat ctt gcg gaa gca cta cct gga tcc ggg ctt ttg acg tcg 499 Gly Asn Asp Leu Ala Glu Ala Leu Pro Gly Ser Gly Leu Leu Thr Ser 120 125 130 aga agc att tagcgtttta gctcgccaat att 531 Arg Ser Ile 135 <210> 138 <211> 136 <212> PRT <213> Corynebacterium glutamicum <400> 138 Met Leu Arg Thr Ile Leu Gly Ser Lys Ile His Arg Ala Thr Val Thr 1 5 10 15 Gln Ala Asp Leu Asp Tyr Val Gly Ser Val Thr Ile Asp Ala Asp Leu 20 25 30 Val His Ala Ala Gly Leu Ile Glu Gly Glu Lys Val Ala Ile Val Asp 35 40 45 Ile Thr Asn Gly Ala Arg Leu Glu Thr Tyr Val Ile Val Gly Asp Ala 50 55 60 Gly Thr Gly Asn Ile Cys Ile Asn Gly Ala Ala Ala His Leu Ile Asn 65 70 75 80 Pro Gly Asp Leu Val Ile Ile Met Ser Tyr Leu Gln Ala Thr Asp Ala 85 90 95 Glu Ala Lys Ala Tyr Glu Pro Lys Ile Val His Val Asp Ala Asp Asn 100 105 110 Arg Ile Val Ala Leu Gly Asn Asp Leu Ala Glu Ala Leu Pro Gly Ser 115 120 125 Gly Leu Leu Thr Ser Arg Ser Ile 130 135 <210> 139 <211> 1053 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1030) <223> RXA01561 <400> 139 gtgcccagaa attctgcttg cactcaccca agccgtttag caaattgaac ctcacgttca 60 taataatgtt cattttcatc gagttctaga aaacacaggc atg ctc acc ctc aac 115 Met Leu Thr Leu Asn 1 5 gat gtc atc acc gcc caa caa cga acc gcc cct cat gtt cga cga acg 163 Asp Val Ile Thr Ala Gln Gln Arg Thr Ala Pro His Val Arg Arg Thr 10 15 20 cca ctt ttc gaa gca gac ccc atc gac ggc aca caa atc tgg atc aaa 211 Pro Leu Phe Glu Ala Asp Pro Ile Asp Gly Thr Gln Ile Trp Ile Lys 25 30 35 gca gag ttc ctc caa aag tgc ggc gtg ttc aaa acg cgt gga gca ttc 259 Ala Glu Phe Leu Gln Lys Cys Gly Val Phe Lys Thr Arg Gly Ala Phe 40 45 50 aac cgc cag ctc gca gct tcg gaa aac gga cta ctc gac cca acg gtt 307 Asn Arg Gln Leu Ala Ala Ser Glu Asn Gly Leu Leu Asp Pro Thr Val 55 60 65 ggc atc gtc gcg gca tca ggc gga aac gca gga ctc gca aat gct ttt 355 Gly Ile Val Ala Ala Ser Gly Gly Asn Ala Gly Leu Ala Asn Ala Phe 70 75 80 85 gcc gca gca tcc tta agc gtt ccc gcc acg gta ttg gtg ccc gaa act 403 Ala Ala Ala Ser Leu Ser Val Pro Ala Thr Val Leu Val Pro Glu Thr 90 95 100 gcc cca caa gta aaa gtt gat cgc ctc aag caa tac ggt gca acc gtg 451 Ala Pro Gln Val Lys Val Asp Arg Leu Lys Gln Tyr Gly Ala Thr Val 105 110 115 caa caa atc gga tct gaa tat gcg gaa gca ttt gag gca gct caa acc 499 Gln Gln Ile Gly Ser Glu Tyr Ala Glu Ala Phe Glu Ala Ala Gln Thr 120 125 130 ttt gag tcg gaa act ggt gct ctg ttt tgc cac gcc tac gac cag ccc 547 Phe Glu Ser Glu Thr Gly Ala Leu Phe Cys His Ala Tyr Asp Gln Pro 135 140 145 gac atc gca gct gga gca ggc gtc att ggg cta gaa att gtc gaa gat 595 Asp Ile Ala Ala Gly Ala Gly Val Ile Gly Leu Glu Ile Val Glu Asp 150 155 160 165 ctt ccc gac gtt gac acc atc gtg gtt gct gtc ggt ggc ggt gga ctc 643 Leu Pro Asp Val Asp Thr Ile Val Val Ala Val Gly Gly Gly Gly Leu 170 175 180 tat gca gga atc gca gcc gtc gta gca gcc cac gac atc aaa gtg gtg 691 Tyr Ala Gly Ile Ala Ala Val Val Ala Ala His Asp Ile Lys Val Val 185 190 195 gcc gtt gaa ccc tcc aaa att cca acc ctg cac aac tca ctc att gcc 739 Ala Val Glu Pro Ser Lys Ile Pro Thr Leu His Asn Ser Leu Ile Ala 200 205 210 ggc caa cca gtc gat gtg aac gtt tct ggt atc gcg gca gat tct ttg 787 Gly Gln Pro Val Asp Val Asn Val Ser Gly Ile Ala Ala Asp Ser Leu 215 220 225 ggg gct cgc caa att gga cga gaa gcc ttt gac atc gca act gcc cat 835 Gly Ala Arg Gln Ile Gly Arg Glu Ala Phe Asp Ile Ala Thr Ala His 230 235 240 245 ccc cca ata ggc gtc cta gtg gac gat gaa gca atc atc gca gct cga 883 Pro Pro Ile Gly Val Leu Val Asp Asp Glu Ala Ile Ile Ala Ala Arg 250 255 260 cgc cac ctc tgg gac aac tac cgc atc cct gcc gag cat ggc gct gcc 931 Arg His Leu Trp Asp Asn Tyr Arg Ile Pro Ala Glu His Gly Ala Ala 265 270 275 gca gca ctc gcc tct ctt acc agt gga gca tac aaa cct gca gca gat 979 Ala Ala Leu Ala Ser Leu Thr Ser Gly Ala Tyr Lys Pro Ala Ala Asp 280 285 290 gaa aaa gtg gca gtc att gtg tgc gga gcg aac act gac ctc aca aca 1027 Glu Lys Val Ala Val Ile Val Cys Gly Ala Asn Thr Asp Leu Thr Thr 295 300 305 ctg tgatgtgatt tcaaacgatc aca 1053 Leu 310 <210> 140 <211> 310 <212> PRT <213> Corynebacterium glutamicum <400> 140 Met Leu Thr Leu Asn Asp Val Ile Thr Ala Gln Gln Arg Thr Ala Pro 1 5 10 15 His Val Arg Arg Thr Pro Leu Phe Glu Ala Asp Pro Ile Asp Gly Thr 20 25 30 Gln Ile Trp Ile Lys Ala Glu Phe Leu Gln Lys Cys Gly Val Phe Lys 35 40 45 Thr Arg Gly Ala Phe Asn Arg Gln Leu Ala Ala Ser Glu Asn Gly Leu 50 55 60 Leu Asp Pro Thr Val Gly Ile Val Ala Ala Ser Gly Gly Asn Ala Gly 65 70 75 80 Leu Ala Asn Ala Phe Ala Ala Ala Ser Leu Ser Val Pro Ala Thr Val 85 90 95 Leu Val Pro Glu Thr Ala Pro Gln Val Lys Val Asp Arg Leu Lys Gln 100 105 110 Tyr Gly Ala Thr Val Gln Gln Ile Gly Ser Glu Tyr Ala Glu Ala Phe 115 120 125 Glu Ala Ala Gln Thr Phe Glu Ser Glu Thr Gly Ala Leu Phe Cys His 130 135 140 Ala Tyr Asp Gln Pro Asp Ile Ala Ala Gly Ala Gly Val Ile Gly Leu 145 150 155 160 Glu Ile Val Glu Asp Leu Pro Asp Val Asp Thr Ile Val Val Ala Val 165 170 175 Gly Gly Gly Gly Leu Tyr Ala Gly Ile Ala Ala Val Val Ala Ala His 180 185 190 Asp Ile Lys Val Val Ala Val Glu Pro Ser Lys Ile Pro Thr Leu His 195 200 205 Asn Ser Leu Ile Ala Gly Gln Pro Val Asp Val Asn Val Ser Gly Ile 210 215 220 Ala Ala Asp Ser Leu Gly Ala Arg Gln Ile Gly Arg Glu Ala Phe Asp 225 230 235 240 Ile Ala Thr Ala His Pro Pro Ile Gly Val Leu Val Asp Asp Glu Ala 245 250 255 Ile Ile Ala Ala Arg Arg His Leu Trp Asp Asn Tyr Arg Ile Pro Ala 260 265 270 Glu His Gly Ala Ala Ala Ala Leu Ala Ser Leu Thr Ser Gly Ala Tyr 275 280 285 Lys Pro Ala Ala Asp Glu Lys Val Ala Val Ile Val Cys Gly Ala Asn 290 295 300 Thr Asp Leu Thr Thr Leu 305 310 <210> 141 <211> 1470 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1447) <223> RXA01850 <400> 141 ttcgtgcaac ttcagactct tacggaggcg atggaccaaa aacaactaca atcaagcaga 60 tcaccttgta caccaccaga gaaaaggccc accctcagcc atg gct atc agt gtt 115 Met Ala Ile Ser Val 1 5 gtt gat cta ttt agc atc ggt atc gga cca tca tcc tca cat acc gtc 163 Val Asp Leu Phe Ser Ile Gly Ile Gly Pro Ser Ser Ser His Thr Val 10 15 20 ggc ccc atg aga gcc gcc ctc acg tat atc tct gaa ttt ccc agc tcg 211 Gly Pro Met Arg Ala Ala Leu Thr Tyr Ile Ser Glu Phe Pro Ser Ser 25 30 35 cat gtc gat atc acg ttg cac gga tcc ctt gcc gcc acc ggt aaa ggc 259 His Val Asp Ile Thr Leu His Gly Ser Leu Ala Ala Thr Gly Lys Gly 40 45 50 cac tgc act gac cgg gcg gta tta ctg ggt ctg gtg gga tgg gaa cca 307 His Cys Thr Asp Arg Ala Val Leu Leu Gly Leu Val Gly Trp Glu Pro 55 60 65 acg ata gtt ccc att gat gct gca ccc tca ccc ggc gcg ccg att cct 355 Thr Ile Val Pro Ile Asp Ala Ala Pro Ser Pro Gly Ala Pro Ile Pro 70 75 80 85 gcg aaa ggt tct gtg aac ggg cca aag gga acg gtg tcg tat tcc ctg 403 Ala Lys Gly Ser Val Asn Gly Pro Lys Gly Thr Val Ser Tyr Ser Leu 90 95 100 acg ttt gat cct cat cct ctt cca gaa cac ccc aat gcc gtt acc ttt 451 Thr Phe Asp Pro His Pro Leu Pro Glu His Pro Asn Ala Val Thr Phe 105 110 115 aaa gga tca acc aca agg act tat ttg tcg gtg ggt ggt ggg ttc att 499 Lys Gly Ser Thr Thr Arg Thr Tyr Leu Ser Val Gly Gly Gly Phe Ile 120 125 130 atg acg ttg gag gat ttc cgg aag ctg gac gat atc gga tca ggt gtg 547 Met Thr Leu Glu Asp Phe Arg Lys Leu Asp Asp Ile Gly Ser Gly Val 135 140 145 tca acc att cat cca gag gca gag gtg cct tgt cct ttt cag aag agt 595 Ser Thr Ile His Pro Glu Ala Glu Val Pro Cys Pro Phe Gln Lys Ser 150 155 160 165 tcc caa tta ctc gca tat ggt cgc gat ttt gcg gag gtc atg aag gat 643 Ser Gln Leu Leu Ala Tyr Gly Arg Asp Phe Ala Glu Val Met Lys Asp 170 175 180 aat gag cgc tta atc cac ggg gat ctt ggc aca gtg gat gcc cat ttg 691 Asn Glu Arg Leu Ile His Gly Asp Leu Gly Thr Val Asp Ala His Leu 185 190 195 gat cga gtg tgg cag att atg cag gag tgc gtg gca caa ggc atc gca 739 Asp Arg Val Trp Gln Ile Met Gln Glu Cys Val Ala Gln Gly Ile Ala 200 205 210 acg ccg ggg att tta ccg ggt ggg ttg aat gtg caa cgt cgg gcg ccg 787 Thr Pro Gly Ile Leu Pro Gly Gly Leu Asn Val Gln Arg Arg Ala Pro 215 220 225 cag gta cac gcg ctg att agc aac ggg gat acg tgt gag ctg ggt gct 835 Gln Val His Ala Leu Ile Ser Asn Gly Asp Thr Cys Glu Leu Gly Ala 230 235 240 245 gat ctt gat gct gtg gag tgg gtg aat ctg tac gcc ttg gcg gtg aat 883 Asp Leu Asp Ala Val Glu Trp Val Asn Leu Tyr Ala Leu Ala Val Asn 250 255 260 gaa gaa aac gcc gct ggt ggt cgt gtg gtt act gct ccg act aat ggt 931 Glu Glu Asn Ala Ala Gly Gly Arg Val Val Thr Ala Pro Thr Asn Gly 265 270 275 gct gcg ggg att att ccg gcg gtg atg cac tat gcg cgg gat ttt ttg 979 Ala Ala Gly Ile Ile Pro Ala Val Met His Tyr Ala Arg Asp Phe Leu 280 285 290 aca ggt ttt ggg gcg gag cag gcg cgg acg ttt ttg tat acc gcg ggt 1027 Thr Gly Phe Gly Ala Glu Gln Ala Arg Thr Phe Leu Tyr Thr Ala Gly 295 300 305 gcg gtg ggc atc atc att aag gaa aat gcc tcg atc tct ggc gcg gag 1075 Ala Val Gly Ile Ile Ile Lys Glu Asn Ala Ser Ile Ser Gly Ala Glu 310 315 320 325 gtg ggg tgt cag ggt gag gtt ggt tca gcg tcc gcg atg gcg gct gcc 1123 Val Gly Cys Gln Gly Glu Val Gly Ser Ala Ser Ala Met Ala Ala Ala 330 335 340 ggg ttg tgt gca gtc tta ggt ggt tct ccg caa cag gtg gaa aac gcc 1171 Gly Leu Cys Ala Val Leu Gly Gly Ser Pro Gln Gln Val Glu Asn Ala 345 350 355 gcg gag att gcg ttg gag cac aat ttg gga ttg acg tgc gat ccg gtg 1219 Ala Glu Ile Ala Leu Glu His Asn Leu Gly Leu Thr Cys Asp Pro Val 360 365 370 ggc ggg tta gtg cag att ccg tgt att gaa cgc aac gct att gct gcc 1267 Gly Gly Leu Val Gln Ile Pro Cys Ile Glu Arg Asn Ala Ile Ala Ala 375 380 385 atg aag tcc atc aat gcg gca agg ctt gcc cgg att ggt gat ggc aac 1315 Met Lys Ser Ile Asn Ala Ala Arg Leu Ala Arg Ile Gly Asp Gly Asn 390 395 400 405 aat cgc gtg agt ttg gat gat gtg gtg gtc acg atg gct gcc acc ggc 1363 Asn Arg Val Ser Leu Asp Asp Val Val Val Thr Met Ala Ala Thr Gly 410 415 420 cgg gac atg ctg acc aaa tat aag gaa acg tcc ctt ggt ggt ttg gca 1411 Arg Asp Met Leu Thr Lys Tyr Lys Glu Thr Ser Leu Gly Gly Leu Ala 425 430 435 acc acc ttg ggc ttc ccg gtg tcg atg acg gag tgt tagcggtacg 1457 Thr Thr Leu Gly Phe Pro Val Ser Met Thr Glu Cys 440 445 gctttaacac ggc 1470 <210> 142 <211> 449 <212> PRT <213> Corynebacterium glutamicum <400> 142 Met Ala Ile Ser Val Val Asp Leu Phe Ser Ile Gly Ile Gly Pro Ser 1 5 10 15 Ser Ser His Thr Val Gly Pro Met Arg Ala Ala Leu Thr Tyr Ile Ser 20 25 30 Glu Phe Pro Ser Ser His Val Asp Ile Thr Leu His Gly Ser Leu Ala 35 40 45 Ala Thr Gly Lys Gly His Cys Thr Asp Arg Ala Val Leu Leu Gly Leu 50 55 60 Val Gly Trp Glu Pro Thr Ile Val Pro Ile Asp Ala Ala Pro Ser Pro 65 70 75 80 Gly Ala Pro Ile Pro Ala Lys Gly Ser Val Asn Gly Pro Lys Gly Thr 85 90 95 Val Ser Tyr Ser Leu Thr Phe Asp Pro His Pro Leu Pro Glu His Pro 100 105 110 Asn Ala Val Thr Phe Lys Gly Ser Thr Thr Arg Thr Tyr Leu Ser Val 115 120 125 Gly Gly Gly Phe Ile Met Thr Leu Glu Asp Phe Arg Lys Leu Asp Asp 130 135 140 Ile Gly Ser Gly Val Ser Thr Ile His Pro Glu Ala Glu Val Pro Cys 145 150 155 160 Pro Phe Gln Lys Ser Ser Gln Leu Leu Ala Tyr Gly Arg Asp Phe Ala 165 170 175 Glu Val Met Lys Asp Asn Glu Arg Leu Ile His Gly Asp Leu Gly Thr 180 185 190 Val Asp Ala His Leu Asp Arg Val Trp Gln Ile Met Gln Glu Cys Val 195 200 205 Ala Gln Gly Ile Ala Thr Pro Gly Ile Leu Pro Gly Gly Leu Asn Val 210 215 220 Gln Arg Arg Ala Pro Gln Val His Ala Leu Ile Ser Asn Gly Asp Thr 225 230 235 240 Cys Glu Leu Gly Ala Asp Leu Asp Ala Val Glu Trp Val Asn Leu Tyr 245 250 255 Ala Leu Ala Val Asn Glu Glu Asn Ala Ala Gly Gly Arg Val Val Thr 260 265 270 Ala Pro Thr Asn Gly Ala Ala Gly Ile Ile Pro Ala Val Met His Tyr 275 280 285 Ala Arg Asp Phe Leu Thr Gly Phe Gly Ala Glu Gln Ala Arg Thr Phe 290 295 300 Leu Tyr Thr Ala Gly Ala Val Gly Ile Ile Ile Lys Glu Asn Ala Ser 305 310 315 320 Ile Ser Gly Ala Glu Val Gly Cys Gln Gly Glu Val Gly Ser Ala Ser 325 330 335 Ala Met Ala Ala Ala Gly Leu Cys Ala Val Leu Gly Gly Ser Pro Gln 340 345 350 Gln Val Glu Asn Ala Ala Glu Ile Ala Leu Glu His Asn Leu Gly Leu 355 360 365 Thr Cys Asp Pro Val Gly Gly Leu Val Gln Ile Pro Cys Ile Glu Arg 370 375 380 Asn Ala Ile Ala Ala Met Lys Ser Ile Asn Ala Ala Arg Leu Ala Arg 385 390 395 400 Ile Gly Asp Gly Asn Asn Arg Val Ser Leu Asp Asp Val Val Val Thr 405 410 415 Met Ala Ala Thr Gly Arg Asp Met Leu Thr Lys Tyr Lys Glu Thr Ser 420 425 430 Leu Gly Gly Leu Ala Thr Thr Leu Gly Phe Pro Val Ser Met Thr Glu 435 440 445 Cys <210> 143 <211> 1425 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1402) <223> RXA00580 <400> 143 ttttatatat gggtatcggc ggtctatgct tgtgggcgta cctgtcccgc gagtgaggtc 60 ttacgcgcgg gattcgtctt gtgaaaggtt agctgacctg atg acc gat gcc cac 115 Met Thr Asp Ala His 1 5 caa gcg gac gat gtc cgt tac cag cca ctg aac gag ctt gat cct gag 163 Gln Ala Asp Asp Val Arg Tyr Gln Pro Leu Asn Glu Leu Asp Pro Glu 10 15 20 gtg gct gct gcc atc gct ggg gaa ctt gcc cgt caa cgc gat aca tta 211 Val Ala Ala Ala Ile Ala Gly Glu Leu Ala Arg Gln Arg Asp Thr Leu 25 30 35 gag atg atc gcg tct gag aac ttc gtt ccc cgt tct gtt ttg cag gcg 259 Glu Met Ile Ala Ser Glu Asn Phe Val Pro Arg Ser Val Leu Gln Ala 40 45 50 cag ggt tct gtt ctt acc aat aag tat gcc gag ggt tac cct ggc cgc 307 Gln Gly Ser Val Leu Thr Asn Lys Tyr Ala Glu Gly Tyr Pro Gly Arg 55 60 65 cgt tac tac ggt ggt tgc gaa caa gtt gac atc att gag gat ctt gca 355 Arg Tyr Tyr Gly Gly Cys Glu Gln Val Asp Ile Ile Glu Asp Leu Ala 70 75 80 85 cgt gat cgt gcg aag gct ctc ttc ggt gca gag ttc gcc aat gtt cag 403 Arg Asp Arg Ala Lys Ala Leu Phe Gly Ala Glu Phe Ala Asn Val Gln 90 95 100 cct cac tct ggc gca cag gct aat gct gct gtg ctg atg act ttg gct 451 Pro His Ser Gly Ala Gln Ala Asn Ala Ala Val Leu Met Thr Leu Ala 105 110 115 gag cca ggc gac aag atc atg ggt ctg tct ttg gct cat ggt ggt cac 499 Glu Pro Gly Asp Lys Ile Met Gly Leu Ser Leu Ala His Gly Gly His 120 125 130 ttg acc cac gga atg aag ttg aac ttc tcc gga aag ctg tac gag gtt 547 Leu Thr His Gly Met Lys Leu Asn Phe Ser Gly Lys Leu Tyr Glu Val 135 140 145 gtt gcg tac ggt gtt gat cct gag acc atg cgt gtt gat atg gat cag 595 Val Ala Tyr Gly Val Asp Pro Glu Thr Met Arg Val Asp Met Asp Gln 150 155 160 165 gtt cgt gag att gct ctg aag gag cag cca aag gta att atc gct ggc 643 Val Arg Glu Ile Ala Leu Lys Glu Gln Pro Lys Val Ile Ile Ala Gly 170 175 180 tgg tct gca tac cct cgc cac ctt gat ttc gag gct ttc cag tct att 691 Trp Ser Ala Tyr Pro Arg His Leu Asp Phe Glu Ala Phe Gln Ser Ile 185 190 195 gct gcg gaa gtt ggc gcg aag ctg tgg gtc gat atg gct cac ttc gct 739 Ala Ala Glu Val Gly Ala Lys Leu Trp Val Asp Met Ala His Phe Ala 200 205 210 ggt ctt gtt gct gct ggt ttg cac cca agc cca gtt cct tac tct gat 787 Gly Leu Val Ala Ala Gly Leu His Pro Ser Pro Val Pro Tyr Ser Asp 215 220 225 gtt gtt tct tcc act gtc cac aag act ttg ggt gga cct cgt tcc ggc 835 Val Val Ser Ser Thr Val His Lys Thr Leu Gly Gly Pro Arg Ser Gly 230 235 240 245 atc att ctg gct aag cag gag tac gcg aag aag ctg aac tct tcc gta 883 Ile Ile Leu Ala Lys Gln Glu Tyr Ala Lys Lys Leu Asn Ser Ser Val 250 255 260 ttc cca ggt cag cag ggt ggt cct ttg atg cac gca gtt gct gcg aag 931 Phe Pro Gly Gln Gln Gly Gly Pro Leu Met His Ala Val Ala Ala Lys 265 270 275 gct act tct ttg aag att gct ggc act gag cag ttc cgt gac cgt cag 979 Ala Thr Ser Leu Lys Ile Ala Gly Thr Glu Gln Phe Arg Asp Arg Gln 280 285 290 gct cgc acg ttg gag ggt gct cgc att ctt gct gag cgt ctg act gct 1027 Ala Arg Thr Leu Glu Gly Ala Arg Ile Leu Ala Glu Arg Leu Thr Ala 295 300 305 tct gat gcg aag gcc gct ggc gtg gat gtc ttg acc ggt ggc act gat 1075 Ser Asp Ala Lys Ala Ala Gly Val Asp Val Leu Thr Gly Gly Thr Asp 310 315 320 325 gtg cac ttg gtt ttg gct gat ctg cgt aac tcc cag atg gat ggc cag 1123 Val His Leu Val Leu Ala Asp Leu Arg Asn Ser Gln Met Asp Gly Gln 330 335 340 cag gcg gaa gat ctg ctg cac gag gtt ggt atc act gtg aac cgt aac 1171 Gln Ala Glu Asp Leu Leu His Glu Val Gly Ile Thr Val Asn Arg Asn 345 350 355 gcg gtt cct ttc gat cct cgt cca cca atg gtt act tct ggt ctg cgt 1219 Ala Val Pro Phe Asp Pro Arg Pro Pro Met Val Thr Ser Gly Leu Arg 360 365 370 att ggt act cct gcg ctg gct acc cgt ggt ttc gat att cct gca ttc 1267 Ile Gly Thr Pro Ala Leu Ala Thr Arg Gly Phe Asp Ile Pro Ala Phe 375 380 385 act gag gtt gca gac atc att ggt act gct ttg gct aat ggt aag tcc 1315 Thr Glu Val Ala Asp Ile Ile Gly Thr Ala Leu Ala Asn Gly Lys Ser 390 395 400 405 gca gac att gag tct ctg cgt ggc cgt gta gca aag ctt gct gca gat 1363 Ala Asp Ile Glu Ser Leu Arg Gly Arg Val Ala Lys Leu Ala Ala Asp 410 415 420 tac cca ctg tat gag ggc ttg gaa gac tgg acc atc gtc taagtttttc 1412 Tyr Pro Leu Tyr Glu Gly Leu Glu Asp Trp Thr Ile Val 425 430 tttgagtttt cat 1425 <210> 144 <211> 434 <212> PRT <213> Corynebacterium glutamicum <400> 144 Met Thr Asp Ala His Gln Ala Asp Asp Val Arg Tyr Gln Pro Leu Asn 1 5 10 15 Glu Leu Asp Pro Glu Val Ala Ala Ala Ile Ala Gly Glu Leu Ala Arg 20 25 30 Gln Arg Asp Thr Leu Glu Met Ile Ala Ser Glu Asn Phe Val Pro Arg 35 40 45 Ser Val Leu Gln Ala Gln Gly Ser Val Leu Thr Asn Lys Tyr Ala Glu 50 55 60 Gly Tyr Pro Gly Arg Arg Tyr Tyr Gly Gly Cys Glu Gln Val Asp Ile 65 70 75 80 Ile Glu Asp Leu Ala Arg Asp Arg Ala Lys Ala Leu Phe Gly Ala Glu 85 90 95 Phe Ala Asn Val Gln Pro His Ser Gly Ala Gln Ala Asn Ala Ala Val 100 105 110 Leu Met Thr Leu Ala Glu Pro Gly Asp Lys Ile Met Gly Leu Ser Leu 115 120 125 Ala His Gly Gly His Leu Thr His Gly Met Lys Leu Asn Phe Ser Gly 130 135 140 Lys Leu Tyr Glu Val Val Ala Tyr Gly Val Asp Pro Glu Thr Met Arg 145 150 155 160 Val Asp Met Asp Gln Val Arg Glu Ile Ala Leu Lys Glu Gln Pro Lys 165 170 175 Val Ile Ile Ala Gly Trp Ser Ala Tyr Pro Arg His Leu Asp Phe Glu 180 185 190 Ala Phe Gln Ser Ile Ala Ala Glu Val Gly Ala Lys Leu Trp Val Asp 195 200 205 Met Ala His Phe Ala Gly Leu Val Ala Ala Gly Leu His Pro Ser Pro 210 215 220 Val Pro Tyr Ser Asp Val Val Ser Ser Thr Val His Lys Thr Leu Gly 225 230 235 240 Gly Pro Arg Ser Gly Ile Ile Leu Ala Lys Gln Glu Tyr Ala Lys Lys 245 250 255 Leu Asn Ser Ser Val Phe Pro Gly Gln Gln Gly Gly Pro Leu Met His 260 265 270 Ala Val Ala Ala Lys Ala Thr Ser Leu Lys Ile Ala Gly Thr Glu Gln 275 280 285 Phe Arg Asp Arg Gln Ala Arg Thr Leu Glu Gly Ala Arg Ile Leu Ala 290 295 300 Glu Arg Leu Thr Ala Ser Asp Ala Lys Ala Ala Gly Val Asp Val Leu 305 310 315 320 Thr Gly Gly Thr Asp Val His Leu Val Leu Ala Asp Leu Arg Asn Ser 325 330 335 Gln Met Asp Gly Gln Gln Ala Glu Asp Leu Leu His Glu Val Gly Ile 340 345 350 Thr Val Asn Arg Asn Ala Val Pro Phe Asp Pro Arg Pro Pro Met Val 355 360 365 Thr Ser Gly Leu Arg Ile Gly Thr Pro Ala Leu Ala Thr Arg Gly Phe 370 375 380 Asp Ile Pro Ala Phe Thr Glu Val Ala Asp Ile Ile Gly Thr Ala Leu 385 390 395 400 Ala Asn Gly Lys Ser Ala Asp Ile Glu Ser Leu Arg Gly Arg Val Ala 405 410 415 Lys Leu Ala Ala Asp Tyr Pro Leu Tyr Glu Gly Leu Glu Asp Trp Thr 420 425 430 Ile Val <210> 145 <211> 401 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(378) <223> RXA01821 <400> 145 cga aac agc caa ggc aaa tgg tgc cca agt acg cga tca cca aaa aat 48 Arg Asn Ser Gln Gly Lys Trp Cys Pro Ser Thr Arg Ser Pro Lys Asn 1 5 10 15 acc agc atc gaa gac aac ggc gat cac gta gtc atc caa gca ggc gaa 96 Thr Ser Ile Glu Asp Asn Gly Asp His Val Val Ile Gln Ala Gly Glu 20 25 30 gaa acc aca atc gtg gac cgc gtt atc gtc acc acc ggc agc tgg aca 144 Glu Thr Thr Ile Val Asp Arg Val Ile Val Thr Thr Gly Ser Trp Thr 35 40 45 agc gag ctc gtg ccc tcc atc gcg cca ctg ctt gaa gtg cga cgc cta 192 Ser Glu Leu Val Pro Ser Ile Ala Pro Leu Leu Glu Val Arg Arg Leu 50 55 60 gtg ctc acc tgg ttc ctg ccc aac aat cca gtg gac ttc caa ccg gaa 240 Val Leu Thr Trp Phe Leu Pro Asn Asn Pro Val Asp Phe Gln Pro Glu 65 70 75 80 aac ctg cca tgc ttc atc cgt gac cgt gat ggc ttc cac gta ttt gga 288 Asn Leu Pro Cys Phe Ile Arg Asp Arg Asp Gly Phe His Val Phe Gly 85 90 95 gca cca tgc gtc gat ggg tac agc atc aaa att gcc gga ttg gat gag 336 Ala Pro Cys Val Asp Gly Tyr Ser Ile Lys Ile Ala Gly Leu Asp Glu 100 105 110 tgg ggc gtt cca tta agc ctc gat cca ccg atg tgc cct cgg 378 Trp Gly Val Pro Leu Ser Leu Asp Pro Pro Met Cys Pro Arg 115 120 125 tgatgtcctg atcccggttc cgg 401 <210> 146 <211> 126 <212> PRT <213> Corynebacterium glutamicum <400> 146 Arg Asn Ser Gln Gly Lys Trp Cys Pro Ser Thr Arg Ser Pro Lys Asn 1 5 10 15 Thr Ser Ile Glu Asp Asn Gly Asp His Val Val Ile Gln Ala Gly Glu 20 25 30 Glu Thr Thr Ile Val Asp Arg Val Ile Val Thr Thr Gly Ser Trp Thr 35 40 45 Ser Glu Leu Val Pro Ser Ile Ala Pro Leu Leu Glu Val Arg Arg Leu 50 55 60 Val Leu Thr Trp Phe Leu Pro Asn Asn Pro Val Asp Phe Gln Pro Glu 65 70 75 80 Asn Leu Pro Cys Phe Ile Arg Asp Arg Asp Gly Phe His Val Phe Gly 85 90 95 Ala Pro Cys Val Asp Gly Tyr Ser Ile Lys Ile Ala Gly Leu Asp Glu 100 105 110 Trp Gly Val Pro Leu Ser Leu Asp Pro Pro Met Cys Pro Arg 115 120 125 <210> 147 <211> 488 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(478) <223> RXN02263 <400> 147 cctgggcaac ccaagtgtat gaaaacgccc tggaaaaagg cgtcggcacc acattgaacc 60 tgtgggaatc acccgcactg gcttgagaga agaaacaaca atg aaa att gcg gta 115 Met Lys Ile Ala Val 1 5 atc ggc ctt gga tca acc ggc tcc atg gca ctg tgg cac tta agt aac 163 Ile Gly Leu Gly Ser Thr Gly Ser Met Ala Leu Trp His Leu Ser Asn 10 15 20 atc cca ggt gta gag gcc atc ggc ttt gaa caa ttc ggc atc tcc cat 211 Ile Pro Gly Val Glu Ala Ile Gly Phe Glu Gln Phe Gly Ile Ser His 25 30 35 ggc tac ggc gca ttc aca ggg gag tcc cga ctg ttt cgc atg gcc tac 259 Gly Tyr Gly Ala Phe Thr Gly Glu Ser Arg Leu Phe Arg Met Ala Tyr 40 45 50 cac gaa ggc agc acc tac gtt ccg ttg ctc aaa cgc gca cga gca cta 307 His Glu Gly Ser Thr Tyr Val Pro Leu Leu Lys Arg Ala Arg Ala Leu 55 60 65 tgg tca tca ctg agc gag att tcc gga cgc gaa ctc ttc cac aac ttc 355 Trp Ser Ser Leu Ser Glu Ile Ser Gly Arg Glu Leu Phe His Asn Phe 70 75 80 85 ggt gtc tta agc acc ggc aag gaa gac gaa gca ccc ttc caa cgc ctg 403 Gly Val Leu Ser Thr Gly Lys Glu Asp Glu Ala Pro Phe Gln Arg Leu 90 95 100 gtg gaa tca gtg gaa cgt tat gag ctg cca cat gaa cga ctt acc gcc 451 Val Glu Ser Val Glu Arg Tyr Glu Leu Pro His Glu Arg Leu Thr Ala 105 110 115 gcg cag atg cgc agc gtt acc cag gtc tagacttccg 488 Ala Gln Met Arg Ser Val Thr Gln Val 120 125 <210> 148 <211> 126 <212> PRT <213> Corynebacterium glutamicum <400> 148 Met Lys Ile Ala Val Ile Gly Leu Gly Ser Thr Gly Ser Met Ala Leu 1 5 10 15 Trp His Leu Ser Asn Ile Pro Gly Val Glu Ala Ile Gly Phe Glu Gln 20 25 30 Phe Gly Ile Ser His Gly Tyr Gly Ala Phe Thr Gly Glu Ser Arg Leu 35 40 45 Phe Arg Met Ala Tyr His Glu Gly Ser Thr Tyr Val Pro Leu Leu Lys 50 55 60 Arg Ala Arg Ala Leu Trp Ser Ser Leu Ser Glu Ile Ser Gly Arg Glu 65 70 75 80 Leu Phe His Asn Phe Gly Val Leu Ser Thr Gly Lys Glu Asp Glu Ala 85 90 95 Pro Phe Gln Arg Leu Val Glu Ser Val Glu Arg Tyr Glu Leu Pro His 100 105 110 Glu Arg Leu Thr Ala Ala Gln Met Arg Ser Val Thr Gln Val 115 120 125 <210> 149 <211> 460 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(460) <223> FRXA02263 <400> 149 cctgggcaac ccaagtgtat gaaaacgccc tggaaaaagg cgtcggcacc acattgaacc 60 tgtgggaatc acccgcactg gcttgagaga agaaacaaca atg aaa att gcg gta 115 Met Lys Ile Ala Val 1 5 atc ggc ctt gga tca acc ggc tcc atg gca ctg tgg cac tta agt aac 163 Ile Gly Leu Gly Ser Thr Gly Ser Met Ala Leu Trp His Leu Ser Asn 10 15 20 atc cca ggt gta gag gcc atc ggc ttt gaa caa ttc ggc atc tcc cat 211 Ile Pro Gly Val Glu Ala Ile Gly Phe Glu Gln Phe Gly Ile Ser His 25 30 35 ggc tac ggc gca ttc aca ggg gag tcc cga ctg ttt cgc atg gcc tac 259 Gly Tyr Gly Ala Phe Thr Gly Glu Ser Arg Leu Phe Arg Met Ala Tyr 40 45 50 cac gaa ggc agc acc tac gtt ccg ttg ctc aaa cgc gca cga gca cta 307 His Glu Gly Ser Thr Tyr Val Pro Leu Leu Lys Arg Ala Arg Ala Leu 55 60 65 tgg tca tca ctg agc gag att tcc gga cgc gaa ctc ttc cac aac ttc 355 Trp Ser Ser Leu Ser Glu Ile Ser Gly Arg Glu Leu Phe His Asn Phe 70 75 80 85 ggt gtc tta agc acc ggc aag gaa gac gaa gca ccc ttc caa cgc ctg 403 Gly Val Leu Ser Thr Gly Lys Glu Asp Glu Ala Pro Phe Gln Arg Leu 90 95 100 gtg gaa tca gtg gaa cgt tat gag ctg cca cat gaa cga ctt acc gcc 451 Val Glu Ser Val Glu Arg Tyr Glu Leu Pro His Glu Arg Leu Thr Ala 105 110 115 gcg cag atg 460 Ala Gln Met 120 <210> 150 <211> 120 <212> PRT <213> Corynebacterium glutamicum <400> 150 Met Lys Ile Ala Val Ile Gly Leu Gly Ser Thr Gly Ser Met Ala Leu 1 5 10 15 Trp His Leu Ser Asn Ile Pro Gly Val Glu Ala Ile Gly Phe Glu Gln 20 25 30 Phe Gly Ile Ser His Gly Tyr Gly Ala Phe Thr Gly Glu Ser Arg Leu 35 40 45 Phe Arg Met Ala Tyr His Glu Gly Ser Thr Tyr Val Pro Leu Leu Lys 50 55 60 Arg Ala Arg Ala Leu Trp Ser Ser Leu Ser Glu Ile Ser Gly Arg Glu 65 70 75 80 Leu Phe His Asn Phe Gly Val Leu Ser Thr Gly Lys Glu Asp Glu Ala 85 90 95 Pro Phe Gln Arg Leu Val Glu Ser Val Glu Arg Tyr Glu Leu Pro His 100 105 110 Glu Arg Leu Thr Ala Ala Gln Met 115 120 <210> 151 <211> 1251 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1228) <223> RXA02176 <400> 151 gggtgctagg aactgacagc ttcagggtta tagttgttgg gtcagatcgt taacgatccc 60 tggccctttt acttccaagc gcagaaagtt gcccgaagac atg acc gac ttc ccc 115 Met Thr Asp Phe Pro 1 5 acc ctg ccc tct gag ttc atc cct ggc gac ggc cgt ttc ggc tgc gga 163 Thr Leu Pro Ser Glu Phe Ile Pro Gly Asp Gly Arg Phe Gly Cys Gly 10 15 20 cct tcc aag gtt cga cca gaa cag att cag gct att gtc gac gga tcc 211 Pro Ser Lys Val Arg Pro Glu Gln Ile Gln Ala Ile Val Asp Gly Ser 25 30 35 gca tcc gtc atc ggt acc tca cac cgt cag ccg gca gta aaa aac gtc 259 Ala Ser Val Ile Gly Thr Ser His Arg Gln Pro Ala Val Lys Asn Val 40 45 50 gtg ggt tca atc cgc gag gga ctc tcc gac ctc ttc tcc ctt cca gaa 307 Val Gly Ser Ile Arg Glu Gly Leu Ser Asp Leu Phe Ser Leu Pro Glu 55 60 65 ggc tac gag atc atc ctt tcc cta ggt ggt gcg acc gca ttc tgg gat 355 Gly Tyr Glu Ile Ile Leu Ser Leu Gly Gly Ala Thr Ala Phe Trp Asp 70 75 80 85 gca gca acc ttc gga ctc att gaa aag aag tcc ggt cac ctt tct ttc 403 Ala Ala Thr Phe Gly Leu Ile Glu Lys Lys Ser Gly His Leu Ser Phe 90 95 100 ggt gag ttc tcc tcc aag ttc gca aag gct tct aag ctt gct cct tgg 451 Gly Glu Phe Ser Ser Lys Phe Ala Lys Ala Ser Lys Leu Ala Pro Trp 105 110 115 ctc gac gag cca gag atc gtc acc gca gaa acc ggt gac tct ccg gcc 499 Leu Asp Glu Pro Glu Ile Val Thr Ala Glu Thr Gly Asp Ser Pro Ala 120 125 130 cca cag gca ttc gaa ggc gcc gat gtt att gca tgg gca cac aac gaa 547 Pro Gln Ala Phe Glu Gly Ala Asp Val Ile Ala Trp Ala His Asn Glu 135 140 145 acc tcc act ggc gcc atg gtt cca gtt ctt cgc ccc gaa ggc tct gaa 595 Thr Ser Thr Gly Ala Met Val Pro Val Leu Arg Pro Glu Gly Ser Glu 150 155 160 165 ggc tcc ctg gtt gcc att gac gca acc tcc ggc gct ggt gga ctg cca 643 Gly Ser Leu Val Ala Ile Asp Ala Thr Ser Gly Ala Gly Gly Leu Pro 170 175 180 gta gac atc aag aac tcc gat gtt tac tac ttc tcc cca cag aag tgc 691 Val Asp Ile Lys Asn Ser Asp Val Tyr Tyr Phe Ser Pro Gln Lys Cys 185 190 195 ttc gca tcc gac ggt ggc ctg tgg ctt gca gcg atg agc cca gca gct 739 Phe Ala Ser Asp Gly Gly Leu Trp Leu Ala Ala Met Ser Pro Ala Ala 200 205 210 ctc gag cgc atc gag aag atc aac gct tcc gat cgc ttc atc cct gag 787 Leu Glu Arg Ile Glu Lys Ile Asn Ala Ser Asp Arg Phe Ile Pro Glu 215 220 225 ttc ctc aac ctg cag acc gca gtg gat aac tcc ctg aag aac cag acc 835 Phe Leu Asn Leu Gln Thr Ala Val Asp Asn Ser Leu Lys Asn Gln Thr 230 235 240 245 tac aac acc cca gct gtt gct acc ttg ctg atg ctg gac aac cag gtc 883 Tyr Asn Thr Pro Ala Val Ala Thr Leu Leu Met Leu Asp Asn Gln Val 250 255 260 aag tgg atg aac tcc aac ggc ggc ctg gat gga atg gtt gct cgc acc 931 Lys Trp Met Asn Ser Asn Gly Gly Leu Asp Gly Met Val Ala Arg Thr 265 270 275 aca gca agc tcc tcc gcc ctg tac aac tgg gct gag gct cgc gag gag 979 Thr Ala Ser Ser Ser Ala Leu Tyr Asn Trp Ala Glu Ala Arg Glu Glu 280 285 290 gca tcc cca tac gtg gca gat gca gct aag cgc tcc ctc gtt gtc ggc 1027 Ala Ser Pro Tyr Val Ala Asp Ala Ala Lys Arg Ser Leu Val Val Gly 295 300 305 acc atc gac ttc gat gac tcc atc gac gca gca gtg atc gct aag ata 1075 Thr Ile Asp Phe Asp Asp Ser Ile Asp Ala Ala Val Ile Ala Lys Ile 310 315 320 325 ctg cgc gca aac ggc atc ctg gac acc gag cct tac cgc aag ctg gga 1123 Leu Arg Ala Asn Gly Ile Leu Asp Thr Glu Pro Tyr Arg Lys Leu Gly 330 335 340 cgc aac cag ctg cgc atc ggt atg ttc cca gcg atc gat tcc acc gat 1171 Arg Asn Gln Leu Arg Ile Gly Met Phe Pro Ala Ile Asp Ser Thr Asp 345 350 355 gtg gaa aag ctc acc gga gca atc gac ttc atc ctc gat ggc ggt ttt 1219 Val Glu Lys Leu Thr Gly Ala Ile Asp Phe Ile Leu Asp Gly Gly Phe 360 365 370 gca agg aag taataccccc actttgaaaa aca 1251 Ala Arg Lys 375 <210> 152 <211> 376 <212> PRT <213> Corynebacterium glutamicum <400> 152 Met Thr Asp Phe Pro Thr Leu Pro Ser Glu Phe Ile Pro Gly Asp Gly 1 5 10 15 Arg Phe Gly Cys Gly Pro Ser Lys Val Arg Pro Glu Gln Ile Gln Ala 20 25 30 Ile Val Asp Gly Ser Ala Ser Val Ile Gly Thr Ser His Arg Gln Pro 35 40 45 Ala Val Lys Asn Val Val Gly Ser Ile Arg Glu Gly Leu Ser Asp Leu 50 55 60 Phe Ser Leu Pro Glu Gly Tyr Glu Ile Ile Leu Ser Leu Gly Gly Ala 65 70 75 80 Thr Ala Phe Trp Asp Ala Ala Thr Phe Gly Leu Ile Glu Lys Lys Ser 85 90 95 Gly His Leu Ser Phe Gly Glu Phe Ser Ser Lys Phe Ala Lys Ala Ser 100 105 110 Lys Leu Ala Pro Trp Leu Asp Glu Pro Glu Ile Val Thr Ala Glu Thr 115 120 125 Gly Asp Ser Pro Ala Pro Gln Ala Phe Glu Gly Ala Asp Val Ile Ala 130 135 140 Trp Ala His Asn Glu Thr Ser Thr Gly Ala Met Val Pro Val Leu Arg 145 150 155 160 Pro Glu Gly Ser Glu Gly Ser Leu Val Ala Ile Asp Ala Thr Ser Gly 165 170 175 Ala Gly Gly Leu Pro Val Asp Ile Lys Asn Ser Asp Val Tyr Tyr Phe 180 185 190 Ser Pro Gln Lys Cys Phe Ala Ser Asp Gly Gly Leu Trp Leu Ala Ala 195 200 205 Met Ser Pro Ala Ala Leu Glu Arg Ile Glu Lys Ile Asn Ala Ser Asp 210 215 220 Arg Phe Ile Pro Glu Phe Leu Asn Leu Gln Thr Ala Val Asp Asn Ser 225 230 235 240 Leu Lys Asn Gln Thr Tyr Asn Thr Pro Ala Val Ala Thr Leu Leu Met 245 250 255 Leu Asp Asn Gln Val Lys Trp Met Asn Ser Asn Gly Gly Leu Asp Gly 260 265 270 Met Val Ala Arg Thr Thr Ala Ser Ser Ser Ala Leu Tyr Asn Trp Ala 275 280 285 Glu Ala Arg Glu Glu Ala Ser Pro Tyr Val Ala Asp Ala Ala Lys Arg 290 295 300 Ser Leu Val Val Gly Thr Ile Asp Phe Asp Asp Ser Ile Asp Ala Ala 305 310 315 320 Val Ile Ala Lys Ile Leu Arg Ala Asn Gly Ile Leu Asp Thr Glu Pro 325 330 335 Tyr Arg Lys Leu Gly Arg Asn Gln Leu Arg Ile Gly Met Phe Pro Ala 340 345 350 Ile Asp Ser Thr Asp Val Glu Lys Leu Thr Gly Ala Ile Asp Phe Ile 355 360 365 Leu Asp Gly Gly Phe Ala Arg Lys 370 375 <210> 153 <211> 1422 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1399) <223> RXN02758 <400> 153 atacatctca cccaattccc cataactaga caattgccca gcaacgactg ataagtctcc 60 aatgtcgtgt tccgcgctca gacatgagac aattgttgcc gtg act gaa ctc atc 115 Val Thr Glu Leu Ile 1 5 cag aat gaa tcc caa gaa atc gct gag ctg gaa gcc ggc cag cag gtt 163 Gln Asn Glu Ser Gln Glu Ile Ala Glu Leu Glu Ala Gly Gln Gln Val 10 15 20 gca ttg cgt gaa ggt tat ctt cct gcg gtg atc aca gtg agc ggt aaa 211 Ala Leu Arg Glu Gly Tyr Leu Pro Ala Val Ile Thr Val Ser Gly Lys 25 30 35 gac cgc cca ggt gtg act gcc gcg ttc ttt agg gtc ttg tcc gct aat 259 Asp Arg Pro Gly Val Thr Ala Ala Phe Phe Arg Val Leu Ser Ala Asn 40 45 50 cag gtt cag gtc ttg gac gtt gag cag tca atg ttc cgt ggc ttt ttg 307 Gln Val Gln Val Leu Asp Val Glu Gln Ser Met Phe Arg Gly Phe Leu 55 60 65 aac ttg gcg gcg ttt gtg ggt atc gca cct gag cgt gtc gag acc gtc 355 Asn Leu Ala Ala Phe Val Gly Ile Ala Pro Glu Arg Val Glu Thr Val 70 75 80 85 acc aca ggc ctg act gac acc ctc aag gtg cat gga cag tcc gtg gtg 403 Thr Thr Gly Leu Thr Asp Thr Leu Lys Val His Gly Gln Ser Val Val 90 95 100 gtg gag ctg cag gaa act gtg cag tcg tcc cgt cct cgt tct tcc cat 451 Val Glu Leu Gln Glu Thr Val Gln Ser Ser Arg Pro Arg Ser Ser His 105 110 115 gtt gtt gtg gtg ttg ggt gat ccg gtt gat gcg ttg gat att tcc cgc 499 Val Val Val Val Leu Gly Asp Pro Val Asp Ala Leu Asp Ile Ser Arg 120 125 130 att ggt cag acc ctg gcg gat tac gat gcc aac att gac acc att cgt 547 Ile Gly Gln Thr Leu Ala Asp Tyr Asp Ala Asn Ile Asp Thr Ile Arg 135 140 145 ggt att tcg gat tac cct gtg acc ggc ctg gag ctg aag gtg act gtg 595 Gly Ile Ser Asp Tyr Pro Val Thr Gly Leu Glu Leu Lys Val Thr Val 150 155 160 165 ccg gat gtc agc cct ggt ggt ggt gaa gcg atg cgt aag gcg ctt gct 643 Pro Asp Val Ser Pro Gly Gly Gly Glu Ala Met Arg Lys Ala Leu Ala 170 175 180 gct ctt acc tct gag ctg aat gtg gat att gcg att gag cgt tct ggt 691 Ala Leu Thr Ser Glu Leu Asn Val Asp Ile Ala Ile Glu Arg Ser Gly 185 190 195 ttg ctg cgt cgt tct aag cgt ctg gtg tgc ttc gat tgt gat tcc acg 739 Leu Leu Arg Arg Ser Lys Arg Leu Val Cys Phe Asp Cys Asp Ser Thr 200 205 210 ttg atc act ggt gag gtc att gag atg ctg gcg gct cac gcg ggc aag 787 Leu Ile Thr Gly Glu Val Ile Glu Met Leu Ala Ala His Ala Gly Lys 215 220 225 gaa gct gaa gtt gcg gca gtt act gag cgt gcg atg cgc ggt gag ctc 835 Glu Ala Glu Val Ala Ala Val Thr Glu Arg Ala Met Arg Gly Glu Leu 230 235 240 245 gat ttc gag gag tct ctg cgt gag cgt gtg aag gcg ttg gct ggt ttg 883 Asp Phe Glu Glu Ser Leu Arg Glu Arg Val Lys Ala Leu Ala Gly Leu 250 255 260 gat gcg tcg gtg atc gat gag gtc gct gcc gct att gag ctg acc cct 931 Asp Ala Ser Val Ile Asp Glu Val Ala Ala Ala Ile Glu Leu Thr Pro 265 270 275 ggt gcg cgc acc acg atc cgt acg ctg aac cgc atg ggt tac cag acc 979 Gly Ala Arg Thr Thr Ile Arg Thr Leu Asn Arg Met Gly Tyr Gln Thr 280 285 290 gct gtt gtt tcc ggt ggt ttc atc cag gtg ttg gaa ggt ttg gct gag 1027 Ala Val Val Ser Gly Gly Phe Ile Gln Val Leu Glu Gly Leu Ala Glu 295 300 305 gag ttg gag ttg gat tat gtc cgc gcc aac act ttg gaa atc gtt gat 1075 Glu Leu Glu Leu Asp Tyr Val Arg Ala Asn Thr Leu Glu Ile Val Asp 310 315 320 325 ggc aag ctg acc ggc aac gtc acc gga aag atc gtt gac cgc gct gcg 1123 Gly Lys Leu Thr Gly Asn Val Thr Gly Lys Ile Val Asp Arg Ala Ala 330 335 340 aag gct gag ttc ctc cgt gag ttc gct gcg gat tct ggc ctg aag atg 1171 Lys Ala Glu Phe Leu Arg Glu Phe Ala Ala Asp Ser Gly Leu Lys Met 345 350 355 tac cag act gtc gct gtc ggt gat ggc gct aat gac atc gat atg ctc 1219 Tyr Gln Thr Val Ala Val Gly Asp Gly Ala Asn Asp Ile Asp Met Leu 360 365 370 tcc gct gcg ggt ctg ggt gtt gct ttc aac gcg aag cct gcg ctg aag 1267 Ser Ala Ala Gly Leu Gly Val Ala Phe Asn Ala Lys Pro Ala Leu Lys 375 380 385 gag att gcg gat act tcc gtg aac cac cca ttc ctc gac gag gtt ttg 1315 Glu Ile Ala Asp Thr Ser Val Asn His Pro Phe Leu Asp Glu Val Leu 390 395 400 405 cac atc atg ggc att tcc cgc gac gag atc gat ctg gcg gat cag gaa 1363 His Ile Met Gly Ile Ser Arg Asp Glu Ile Asp Leu Ala Asp Gln Glu 410 415 420 gac ggc act ttc cac cgc gtt cca ttg acc aat gcc taaagattcg 1409 Asp Gly Thr Phe His Arg Val Pro Leu Thr Asn Ala 425 430 tttctcgacg ccc 1422 <210> 154 <211> 433 <212> PRT <213> Corynebacterium glutamicum <400> 154 Val Thr Glu Leu Ile Gln Asn Glu Ser Gln Glu Ile Ala Glu Leu Glu 1 5 10 15 Ala Gly Gln Gln Val Ala Leu Arg Glu Gly Tyr Leu Pro Ala Val Ile 20 25 30 Thr Val Ser Gly Lys Asp Arg Pro Gly Val Thr Ala Ala Phe Phe Arg 35 40 45 Val Leu Ser Ala Asn Gln Val Gln Val Leu Asp Val Glu Gln Ser Met 50 55 60 Phe Arg Gly Phe Leu Asn Leu Ala Ala Phe Val Gly Ile Ala Pro Glu 65 70 75 80 Arg Val Glu Thr Val Thr Thr Gly Leu Thr Asp Thr Leu Lys Val His 85 90 95 Gly Gln Ser Val Val Val Glu Leu Gln Glu Thr Val Gln Ser Ser Arg 100 105 110 Pro Arg Ser Ser His Val Val Val Val Leu Gly Asp Pro Val Asp Ala 115 120 125 Leu Asp Ile Ser Arg Ile Gly Gln Thr Leu Ala Asp Tyr Asp Ala Asn 130 135 140 Ile Asp Thr Ile Arg Gly Ile Ser Asp Tyr Pro Val Thr Gly Leu Glu 145 150 155 160 Leu Lys Val Thr Val Pro Asp Val Ser Pro Gly Gly Gly Glu Ala Met 165 170 175 Arg Lys Ala Leu Ala Ala Leu Thr Ser Glu Leu Asn Val Asp Ile Ala 180 185 190 Ile Glu Arg Ser Gly Leu Leu Arg Arg Ser Lys Arg Leu Val Cys Phe 195 200 205 Asp Cys Asp Ser Thr Leu Ile Thr Gly Glu Val Ile Glu Met Leu Ala 210 215 220 Ala His Ala Gly Lys Glu Ala Glu Val Ala Ala Val Thr Glu Arg Ala 225 230 235 240 Met Arg Gly Glu Leu Asp Phe Glu Glu Ser Leu Arg Glu Arg Val Lys 245 250 255 Ala Leu Ala Gly Leu Asp Ala Ser Val Ile Asp Glu Val Ala Ala Ala 260 265 270 Ile Glu Leu Thr Pro Gly Ala Arg Thr Thr Ile Arg Thr Leu Asn Arg 275 280 285 Met Gly Tyr Gln Thr Ala Val Val Ser Gly Gly Phe Ile Gln Val Leu 290 295 300 Glu Gly Leu Ala Glu Glu Leu Glu Leu Asp Tyr Val Arg Ala Asn Thr 305 310 315 320 Leu Glu Ile Val Asp Gly Lys Leu Thr Gly Asn Val Thr Gly Lys Ile 325 330 335 Val Asp Arg Ala Ala Lys Ala Glu Phe Leu Arg Glu Phe Ala Ala Asp 340 345 350 Ser Gly Leu Lys Met Tyr Gln Thr Val Ala Val Gly Asp Gly Ala Asn 355 360 365 Asp Ile Asp Met Leu Ser Ala Ala Gly Leu Gly Val Ala Phe Asn Ala 370 375 380 Lys Pro Ala Leu Lys Glu Ile Ala Asp Thr Ser Val Asn His Pro Phe 385 390 395 400 Leu Asp Glu Val Leu His Ile Met Gly Ile Ser Arg Asp Glu Ile Asp 405 410 415 Leu Ala Asp Gln Glu Asp Gly Thr Phe His Arg Val Pro Leu Thr Asn 420 425 430 Ala <210> 155 <211> 490 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(490) <223> FRXA02479 <400> 155 atacatctca cccaattccc cataactaga caattgccca gcaacgactg ataagtctcc 60 aatgtcgtgt tccgcgctca gacatgagac aattgttgcc gtg act gaa ctc atc 115 Val Thr Glu Leu Ile 1 5 cag aat gaa tcc caa gaa atc gct gag ctg gaa gcc ggc cag cag gtt 163 Gln Asn Glu Ser Gln Glu Ile Ala Glu Leu Glu Ala Gly Gln Gln Val 10 15 20 gca ttg cgt gaa ggt tat ctt cct gcg gtg atc aca gtg agc ggt aaa 211 Ala Leu Arg Glu Gly Tyr Leu Pro Ala Val Ile Thr Val Ser Gly Lys 25 30 35 gac cgc cca ggt gtg act gcc gcg ttc ttt agg gtc ttg tcc gct aat 259 Asp Arg Pro Gly Val Thr Ala Ala Phe Phe Arg Val Leu Ser Ala Asn 40 45 50 cag gtt cag gtc ttg gac gtt gag cag tca atg ttc cgt ggc ttt ttg 307 Gln Val Gln Val Leu Asp Val Glu Gln Ser Met Phe Arg Gly Phe Leu 55 60 65 aac ttg gcg gcg ttt gtg ggt atc gca cct gag cgt gtc gag acc gtc 355 Asn Leu Ala Ala Phe Val Gly Ile Ala Pro Glu Arg Val Glu Thr Val 70 75 80 85 acc aca ggc ctg act gac acc ctc aag gtg cat gga cag tcc gtg gtg 403 Thr Thr Gly Leu Thr Asp Thr Leu Lys Val His Gly Gln Ser Val Val 90 95 100 gtg gag ctg cag gaa act gtg cag tcg tcc cgt cct cgt tct tcc cat 451 Val Glu Leu Gln Glu Thr Val Gln Ser Ser Arg Pro Arg Ser Ser His 105 110 115 gtt gtt gtg gtg ttg ggt gat ccg gtt gat gcg ctg gat 490 Val Val Val Val Leu Gly Asp Pro Val Asp Ala Leu Asp 120 125 130 <210> 156 <211> 130 <212> PRT <213> Corynebacterium glutamicum <400> 156 Val Thr Glu Leu Ile Gln Asn Glu Ser Gln Glu Ile Ala Glu Leu Glu 1 5 10 15 Ala Gly Gln Gln Val Ala Leu Arg Glu Gly Tyr Leu Pro Ala Val Ile 20 25 30 Thr Val Ser Gly Lys Asp Arg Pro Gly Val Thr Ala Ala Phe Phe Arg 35 40 45 Val Leu Ser Ala Asn Gln Val Gln Val Leu Asp Val Glu Gln Ser Met 50 55 60 Phe Arg Gly Phe Leu Asn Leu Ala Ala Phe Val Gly Ile Ala Pro Glu 65 70 75 80 Arg Val Glu Thr Val Thr Thr Gly Leu Thr Asp Thr Leu Lys Val His 85 90 95 Gly Gln Ser Val Val Val Glu Leu Gln Glu Thr Val Gln Ser Ser Arg 100 105 110 Pro Arg Ser Ser His Val Val Val Val Leu Gly Asp Pro Val Asp Ala 115 120 125 Leu Asp 130 <210> 157 <211> 558 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(535) <223> FRXA02758 <400> 157 aaggcgttgg ctggtttgga tgcgtcggtg atcgatgagg tcgctgccgc tattgagctg 60 acccttggtg cgcgcaccac gatccgtacg gttgaaccgc atg ggt tac cag acc 115 Met Gly Tyr Gln Thr 1 5 gct gtt gtt tcc ggt ggt ttc atc cag gtg ttg gaa ggt ttg gct gag 163 Ala Val Val Ser Gly Gly Phe Ile Gln Val Leu Glu Gly Leu Ala Glu 10 15 20 gag ttg gag ttg gat tat gtc cgc gcc aac act ttg gaa atc gtt gat 211 Glu Leu Glu Leu Asp Tyr Val Arg Ala Asn Thr Leu Glu Ile Val Asp 25 30 35 ggc aag ctg acc ggc aac gtc acc gga aag atc gtt gac cgc gct gcg 259 Gly Lys Leu Thr Gly Asn Val Thr Gly Lys Ile Val Asp Arg Ala Ala 40 45 50 aag gct gag ttc ctc cgt gag ttc gct gcg gat tct ggc ctg aag atg 307 Lys Ala Glu Phe Leu Arg Glu Phe Ala Ala Asp Ser Gly Leu Lys Met 55 60 65 tac cag act gtc gct gtc ggt gat ggc gct aat gac atc gat atg ctc 355 Tyr Gln Thr Val Ala Val Gly Asp Gly Ala Asn Asp Ile Asp Met Leu 70 75 80 85 tcc gct gcg ggt ctg ggt gtt gct ttc aac gcg aag cct gcg ctg aag 403 Ser Ala Ala Gly Leu Gly Val Ala Phe Asn Ala Lys Pro Ala Leu Lys 90 95 100 gag att gcg gat act tcc gtg aac cac cca ttc ctc gac gag gtt ttg 451 Glu Ile Ala Asp Thr Ser Val Asn His Pro Phe Leu Asp Glu Val Leu 105 110 115 cac atc atg ggc att tcc cgc gac gag atc gat ctg gcg gat cag gaa 499 His Ile Met Gly Ile Ser Arg Asp Glu Ile Asp Leu Ala Asp Gln Glu 120 125 130 gac ggc act ttc cac cgc gtt cca ttg acc aat gcc taaagattcg 545 Asp Gly Thr Phe His Arg Val Pro Leu Thr Asn Ala 135 140 145 tttctcgacg ccc 558 <210> 158 <211> 145 <212> PRT <213> Corynebacterium glutamicum <400> 158 Met Gly Tyr Gln Thr Ala Val Val Ser Gly Gly Phe Ile Gln Val Leu 1 5 10 15 Glu Gly Leu Ala Glu Glu Leu Glu Leu Asp Tyr Val Arg Ala Asn Thr 20 25 30 Leu Glu Ile Val Asp Gly Lys Leu Thr Gly Asn Val Thr Gly Lys Ile 35 40 45 Val Asp Arg Ala Ala Lys Ala Glu Phe Leu Arg Glu Phe Ala Ala Asp 50 55 60 Ser Gly Leu Lys Met Tyr Gln Thr Val Ala Val Gly Asp Gly Ala Asn 65 70 75 80 Asp Ile Asp Met Leu Ser Ala Ala Gly Leu Gly Val Ala Phe Asn Ala 85 90 95 Lys Pro Ala Leu Lys Glu Ile Ala Asp Thr Ser Val Asn His Pro Phe 100 105 110 Leu Asp Glu Val Leu His Ile Met Gly Ile Ser Arg Asp Glu Ile Asp 115 120 125 Leu Ala Asp Gln Glu Asp Gly Thr Phe His Arg Val Pro Leu Thr Asn 130 135 140 Ala 145 <210> 159 <211> 205 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (72)..(182) <223> FRXA02759 <400> 159 tcttacttct aagctgaatg tgatattgcg attaagcgtt ctggtttgct gcgtcgttct 60 aagcgtctgg t gtg ctt cga ttg tat ccc acg ttg atc act ggt gag gtc 110 Val Leu Arg Leu Tyr Pro Thr Leu Ile Thr Gly Glu Val 1 5 10 att gag atg ctg gcg gct cac gcg ggc aag gaa gct aaa gtt gcg gca 158 Ile Glu Met Leu Ala Ala His Ala Gly Lys Glu Ala Lys Val Ala Ala 15 20 25 gtt act gag cgt gcg atg cgc ggg tgagctcgat ttcgaggagt ctc 205 Val Thr Glu Arg Ala Met Arg Gly 30 35 <210> 160 <211> 37 <212> PRT <213> Corynebacterium glutamicum <400> 160 Val Leu Arg Leu Tyr Pro Thr Leu Ile Thr Gly Glu Val Ile Glu Met 1 5 10 15 Leu Ala Ala His Ala Gly Lys Glu Ala Lys Val Ala Ala Val Thr Glu 20 25 30 Arg Ala Met Arg Gly 35 <210> 161 <211> 1188 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1165) <223> RXA02501 <400> 161 cgccccgaaa gctttaccat ggatacgata ctcaatggag atatccatta tcggtttggc 60 gtctgtgcgc tcatgaacca ggaaggtttt tgtttgtctc atg agc tct gaa gga 115 Met Ser Ser Glu Gly 1 5 aga aac cac aac tgg gac tac gcc gcc atc ggc acc cca gag gat ttc 163 Arg Asn His Asn Trp Asp Tyr Ala Ala Ile Gly Thr Pro Glu Asp Phe 10 15 20 ctc gcc agc tgg agc gca tcc cgc gga aat cta cga cgc ttt ttc gaa 211 Leu Ala Ser Trp Ser Ala Ser Arg Gly Asn Leu Arg Arg Phe Phe Glu 25 30 35 gac cac gca gcc gcc ccc ata aac gat gcc gcc cag cgc caa gca ggt 259 Asp His Ala Ala Ala Pro Ile Asn Asp Ala Ala Gln Arg Gln Ala Gly 40 45 50 gaa gcc gca gca acc caa gcc gtc gca gcg atc tac ggc atg gag ctc 307 Glu Ala Ala Ala Thr Gln Ala Val Ala Ala Ile Tyr Gly Met Glu Leu 55 60 65 aac gaa ttc aac gca ggt gtc gac gcc gtc gcc ggc gcc atc gaa tct 355 Asn Glu Phe Asn Ala Gly Val Asp Ala Val Ala Gly Ala Ile Glu Ser 70 75 80 85 gcc ggc gcc atc cac gtc agc atc ccc gat ccc gat gtc ccc caa gat 403 Ala Gly Ala Ile His Val Ser Ile Pro Asp Pro Asp Val Pro Gln Asp 90 95 100 gtc gga gcc gca gca ttt ttc gac gtc gac aac acc ctc atc caa ggc 451 Val Gly Ala Ala Ala Phe Phe Asp Val Asp Asn Thr Leu Ile Gln Gly 105 110 115 tcc tcc ctc atc gtt ttc gcc caa gga ctc ttc cgg aag aaa ttc ttc 499 Ser Ser Leu Ile Val Phe Ala Gln Gly Leu Phe Arg Lys Lys Phe Phe 120 125 130 acc atc aaa gaa atc ctc ccc gtg gtg tgg aaa caa gtg aaa ttc aaa 547 Thr Ile Lys Glu Ile Leu Pro Val Val Trp Lys Gln Val Lys Phe Lys 135 140 145 ctc acc ggc tcc gaa aac gcc gac gac gtc tcc cgc ggc cgc gaa caa 595 Leu Thr Gly Ser Glu Asn Ala Asp Asp Val Ser Arg Gly Arg Glu Gln 150 155 160 165 gcc ctc gaa ttc atc aaa ggc cgc ccc gtc caa gaa cta gtt gac ctc 643 Ala Leu Glu Phe Ile Lys Gly Arg Pro Val Gln Glu Leu Val Asp Leu 170 175 180 tgc gaa gaa atc gtc gac caa cgc atg gcc gac aaa atg tgg ccc ggc 691 Cys Glu Glu Ile Val Asp Gln Arg Met Ala Asp Lys Met Trp Pro Gly 185 190 195 acc aaa caa ctc gcc gac atg cac atc gcc gcc ggc cac caa gtc tgg 739 Thr Lys Gln Leu Ala Asp Met His Ile Ala Ala Gly His Gln Val Trp 200 205 210 ctc gtc tcc gca acc ccc gtc caa ctc gcc caa atc ctg gca caa cgc 787 Leu Val Ser Ala Thr Pro Val Gln Leu Ala Gln Ile Leu Ala Gln Arg 215 220 225 ctc ggc ttc acc gga gcg atc ggc aca gtc gca gaa gca aaa gat gga 835 Leu Gly Phe Thr Gly Ala Ile Gly Thr Val Ala Glu Ala Lys Asp Gly 230 235 240 245 gta ttc acc ggc cga ctc gtc ggc gac atc ctc cac gga ccc ggc aaa 883 Val Phe Thr Gly Arg Leu Val Gly Asp Ile Leu His Gly Pro Gly Lys 250 255 260 aga cac gca gtc gca gca ctc gca tcc atc gaa caa ctc gac ctc acc 931 Arg His Ala Val Ala Ala Leu Ala Ser Ile Glu Gln Leu Asp Leu Thr 265 270 275 cga tgc acc gcc tac tcc gac tcc atc aac gac ctc ccc atg ctc tcc 979 Arg Cys Thr Ala Tyr Ser Asp Ser Ile Asn Asp Leu Pro Met Leu Ser 280 285 290 atg gtc ggc acc gcc gtc gca gta aac ccc gac tcc aaa ctc cgc aaa 1027 Met Val Gly Thr Ala Val Ala Val Asn Pro Asp Ser Lys Leu Arg Lys 295 300 305 gaa gcc gaa acc cga ggc tgg gac gtc cgc gat ttc cga agc atc cgc 1075 Glu Ala Glu Thr Arg Gly Trp Asp Val Arg Asp Phe Arg Ser Ile Arg 310 315 320 325 aaa gcc acc cgc gaa tac gga atc ccc gcc ctg gtc acc gcc gca ttc 1123 Lys Ala Thr Arg Glu Tyr Gly Ile Pro Ala Leu Val Thr Ala Ala Phe 330 335 340 agt gtc gcc ggc tgg agt cta cgc cgc cga tgg aga aaa caa 1165 Ser Val Ala Gly Trp Ser Leu Arg Arg Arg Trp Arg Lys Gln 345 350 355 taacgcacag gagccgtttt aag 1188 <210> 162 <211> 355 <212> PRT <213> Corynebacterium glutamicum <400> 162 Met Ser Ser Glu Gly Arg Asn His Asn Trp Asp Tyr Ala Ala Ile Gly 1 5 10 15 Thr Pro Glu Asp Phe Leu Ala Ser Trp Ser Ala Ser Arg Gly Asn Leu 20 25 30 Arg Arg Phe Phe Glu Asp His Ala Ala Ala Pro Ile Asn Asp Ala Ala 35 40 45 Gln Arg Gln Ala Gly Glu Ala Ala Ala Thr Gln Ala Val Ala Ala Ile 50 55 60 Tyr Gly Met Glu Leu Asn Glu Phe Asn Ala Gly Val Asp Ala Val Ala 65 70 75 80 Gly Ala Ile Glu Ser Ala Gly Ala Ile His Val Ser Ile Pro Asp Pro 85 90 95 Asp Val Pro Gln Asp Val Gly Ala Ala Ala Phe Phe Asp Val Asp Asn 100 105 110 Thr Leu Ile Gln Gly Ser Ser Leu Ile Val Phe Ala Gln Gly Leu Phe 115 120 125 Arg Lys Lys Phe Phe Thr Ile Lys Glu Ile Leu Pro Val Val Trp Lys 130 135 140 Gln Val Lys Phe Lys Leu Thr Gly Ser Glu Asn Ala Asp Asp Val Ser 145 150 155 160 Arg Gly Arg Glu Gln Ala Leu Glu Phe Ile Lys Gly Arg Pro Val Gln 165 170 175 Glu Leu Val Asp Leu Cys Glu Glu Ile Val Asp Gln Arg Met Ala Asp 180 185 190 Lys Met Trp Pro Gly Thr Lys Gln Leu Ala Asp Met His Ile Ala Ala 195 200 205 Gly His Gln Val Trp Leu Val Ser Ala Thr Pro Val Gln Leu Ala Gln 210 215 220 Ile Leu Ala Gln Arg Leu Gly Phe Thr Gly Ala Ile Gly Thr Val Ala 225 230 235 240 Glu Ala Lys Asp Gly Val Phe Thr Gly Arg Leu Val Gly Asp Ile Leu 245 250 255 His Gly Pro Gly Lys Arg His Ala Val Ala Ala Leu Ala Ser Ile Glu 260 265 270 Gln Leu Asp Leu Thr Arg Cys Thr Ala Tyr Ser Asp Ser Ile Asn Asp 275 280 285 Leu Pro Met Leu Ser Met Val Gly Thr Ala Val Ala Val Asn Pro Asp 290 295 300 Ser Lys Leu Arg Lys Glu Ala Glu Thr Arg Gly Trp Asp Val Arg Asp 305 310 315 320 Phe Arg Ser Ile Arg Lys Ala Thr Arg Glu Tyr Gly Ile Pro Ala Leu 325 330 335 Val Thr Ala Ala Phe Ser Val Ala Gly Trp Ser Leu Arg Arg Arg Trp 340 345 350 Arg Lys Gln 355 <210> 163 <211> 558 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(535) <223> RXN03105 <400> 163 ggttggggtc atcaaaggat gcggacatcg ctgtggggtt gtgtaataat tgcacctgtg 60 aggtgccttt ctggcaggtg aatcaggact ctaagcaagc ttg att ctt cca gtt 115 Leu Ile Leu Pro Val 1 5 cag gag ggc att tcc tat ttt ccc acg ccg tta cac ctg aat cac atc 163 Gln Glu Gly Ile Ser Tyr Phe Pro Thr Pro Leu His Leu Asn His Ile 10 15 20 ggt gga tcc agg tta agc gca cat gta gaa gat gaa gat ctc cgc ctc 211 Gly Gly Ser Arg Leu Ser Ala His Val Glu Asp Glu Asp Leu Arg Leu 25 30 35 gac cgg gac gca gtc tct gaa ttt ggt cgg aaa acc cac gaa ctc ttc 259 Asp Arg Asp Ala Val Ser Glu Phe Gly Arg Lys Thr His Glu Leu Phe 40 45 50 ccc ggg gtc aac cca gag ccc aac cgt ttc agc gtc cac tat gac acc 307 Pro Gly Val Asn Pro Glu Pro Asn Arg Phe Ser Val His Tyr Asp Thr 55 60 65 tac act gca gac aaa tct cca att atc gac gcg gtt gac aat gtc att 355 Tyr Thr Ala Asp Lys Ser Pro Ile Ile Asp Ala Val Asp Asn Val Ile 70 75 80 85 gtg ctc acc gga gga tcc gga cac gcc ttc aag ctc tct cca gct tat 403 Val Leu Thr Gly Gly Ser Gly His Ala Phe Lys Leu Ser Pro Ala Tyr 90 95 100 ggc gaa ctc gca gca caa cga gcg gtc gga aac acc tcg ccg ctg tac 451 Gly Glu Leu Ala Ala Gln Arg Ala Val Gly Asn Thr Ser Pro Leu Tyr 105 110 115 agc gaa gac ttt cgg atc gcc tcg cat gaa cca atc aaa gag cgg tgc 499 Ser Glu Asp Phe Arg Ile Ala Ser His Glu Pro Ile Lys Glu Arg Cys 120 125 130 acg tat aga aag cta acc ttt tta agt gcg cgg ttt tagggtgaga 545 Thr Tyr Arg Lys Leu Thr Phe Leu Ser Ala Arg Phe 135 140 145 atctaacgct gag 558 <210> 164 <211> 145 <212> PRT <213> Corynebacterium glutamicum <400> 164 Leu Ile Leu Pro Val Gln Glu Gly Ile Ser Tyr Phe Pro Thr Pro Leu 1 5 10 15 His Leu Asn His Ile Gly Gly Ser Arg Leu Ser Ala His Val Glu Asp 20 25 30 Glu Asp Leu Arg Leu Asp Arg Asp Ala Val Ser Glu Phe Gly Arg Lys 35 40 45 Thr His Glu Leu Phe Pro Gly Val Asn Pro Glu Pro Asn Arg Phe Ser 50 55 60 Val His Tyr Asp Thr Tyr Thr Ala Asp Lys Ser Pro Ile Ile Asp Ala 65 70 75 80 Val Asp Asn Val Ile Val Leu Thr Gly Gly Ser Gly His Ala Phe Lys 85 90 95 Leu Ser Pro Ala Tyr Gly Glu Leu Ala Ala Gln Arg Ala Val Gly Asn 100 105 110 Thr Ser Pro Leu Tyr Ser Glu Asp Phe Arg Ile Ala Ser His Glu Pro 115 120 125 Ile Lys Glu Arg Cys Thr Tyr Arg Lys Leu Thr Phe Leu Ser Ala Arg 130 135 140 Phe 145 <210> 165 <211> 687 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (62)..(664) <223> RXS01130 <400> 165 agttcgtggc ggatgctgtg aacgtttccg gtggtcgcgt gggcgaagag gttctgtgtg 60 g atg gat ctg gct cgc aag ctt ggt ctt ctt gct ggc aag ctt gtc gac 109 Met Asp Leu Ala Arg Lys Leu Gly Leu Leu Ala Gly Lys Leu Val Asp 1 5 10 15 gcc gcc cca gtc tcc att gag gtt gag gct cga ggc gag ctt tct tcc 157 Ala Ala Pro Val Ser Ile Glu Val Glu Ala Arg Gly Glu Leu Ser Ser 20 25 30 gag cag gtc aat gca ctt ggt ttg tcc gct gtt cgt ggt ttg ttc tcc 205 Glu Gln Val Asn Ala Leu Gly Leu Ser Ala Val Arg Gly Leu Phe Ser 35 40 45 gga att atc gaa gag tcc gtt act ttc gtc aac gct cct cgc att gct 253 Gly Ile Ile Glu Glu Ser Val Thr Phe Val Asn Ala Pro Arg Ile Ala 50 55 60 gaa gag cgt ggc ctg gac atc tcc gtg aag acc aac tct gag tct gtt 301 Glu Glu Arg Gly Leu Asp Ile Ser Val Lys Thr Asn Ser Glu Ser Val 65 70 75 80 act cac cgt tcc gtc ctg cag gtc aag gtc att act ggc agc ggc gcg 349 Thr His Arg Ser Val Leu Gln Val Lys Val Ile Thr Gly Ser Gly Ala 85 90 95 agc gca act gtt gtt ggt gcc ctg act ggt ctt gag cgc gtt gag aag 397 Ser Ala Thr Val Val Gly Ala Leu Thr Gly Leu Glu Arg Val Glu Lys 100 105 110 atc acc cgc atc aat ggc cgt ggc ctg gat ctg cgc gca gag ggt ctg 445 Ile Thr Arg Ile Asn Gly Arg Gly Leu Asp Leu Arg Ala Glu Gly Leu 115 120 125 aac ctc ttc ctg cag tac act gac gct cct ggt gca ctg ggt acc gtt 493 Asn Leu Phe Leu Gln Tyr Thr Asp Ala Pro Gly Ala Leu Gly Thr Val 130 135 140 ggt acc aag ctg ggt gct gct ggc atc aac atc gag gct gct gcg ttg 541 Gly Thr Lys Leu Gly Ala Ala Gly Ile Asn Ile Glu Ala Ala Ala Leu 145 150 155 160 act cag gct gag aag ggt gac ggc gct gtc ctg atc ctg cgt gtt gag 589 Thr Gln Ala Glu Lys Gly Asp Gly Ala Val Leu Ile Leu Arg Val Glu 165 170 175 tcc gct gtc tct gaa gag ctg gaa gct gaa atc aac gct gag ttg ggt 637 Ser Ala Val Ser Glu Glu Leu Glu Ala Glu Ile Asn Ala Glu Leu Gly 180 185 190 gct act tcc ttc cag gtt gat ctt gac taattagaga tccatttgct 684 Ala Thr Ser Phe Gln Val Asp Leu Asp 195 200 tga 687 <210> 166 <211> 201 <212> PRT <213> Corynebacterium glutamicum <400> 166 Met Asp Leu Ala Arg Lys Leu Gly Leu Leu Ala Gly Lys Leu Val Asp 1 5 10 15 Ala Ala Pro Val Ser Ile Glu Val Glu Ala Arg Gly Glu Leu Ser Ser 20 25 30 Glu Gln Val Asn Ala Leu Gly Leu Ser Ala Val Arg Gly Leu Phe Ser 35 40 45 Gly Ile Ile Glu Glu Ser Val Thr Phe Val Asn Ala Pro Arg Ile Ala 50 55 60 Glu Glu Arg Gly Leu Asp Ile Ser Val Lys Thr Asn Ser Glu Ser Val 65 70 75 80 Thr His Arg Ser Val Leu Gln Val Lys Val Ile Thr Gly Ser Gly Ala 85 90 95 Ser Ala Thr Val Val Gly Ala Leu Thr Gly Leu Glu Arg Val Glu Lys 100 105 110 Ile Thr Arg Ile Asn Gly Arg Gly Leu Asp Leu Arg Ala Glu Gly Leu 115 120 125 Asn Leu Phe Leu Gln Tyr Thr Asp Ala Pro Gly Ala Leu Gly Thr Val 130 135 140 Gly Thr Lys Leu Gly Ala Ala Gly Ile Asn Ile Glu Ala Ala Ala Leu 145 150 155 160 Thr Gln Ala Glu Lys Gly Asp Gly Ala Val Leu Ile Leu Arg Val Glu 165 170 175 Ser Ala Val Ser Glu Glu Leu Glu Ala Glu Ile Asn Ala Glu Leu Gly 180 185 190 Ala Thr Ser Phe Gln Val Asp Leu Asp 195 200 <210> 167 <211> 604 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(604) <223> RXS03112 <400> 167 gtgagcacgc aatttctttg ctgctgtcta ctgctcgcca gatcctgctg ctgatgcgac 60 gctgcgtgag ggcgagtgga agcggtcttc tttcaacggt gtg gaa att ttc gga 115 Val Glu Ile Phe Gly 1 5 aaa act gtc ggt atc gtc ggt ttt ggc cac att ggt cag ttg ttt gct 163 Lys Thr Val Gly Ile Val Gly Phe Gly His Ile Gly Gln Leu Phe Ala 10 15 20 cag cgt ctt gct gcg ttt gag acc acc att gtt gct tac gat cct tac 211 Gln Arg Leu Ala Ala Phe Glu Thr Thr Ile Val Ala Tyr Asp Pro Tyr 25 30 35 gct aac cct gct cgt gcg gct cag ctg aac gtt gag ttg gtt gag ttg 259 Ala Asn Pro Ala Arg Ala Ala Gln Leu Asn Val Glu Leu Val Glu Leu 40 45 50 gat gag ctg atg agc cgt tct gac ttt gtc acc att cac ctt cct aag 307 Asp Glu Leu Met Ser Arg Ser Asp Phe Val Thr Ile His Leu Pro Lys 55 60 65 acc aag gaa act gct ggc atg ttt gat gcg cac ctc ctt gct aag tcc 355 Thr Lys Glu Thr Ala Gly Met Phe Asp Ala His Leu Leu Ala Lys Ser 70 75 80 85 aag aag ggc cag atc atc atc aac gct gct cgt ggt ggc ctt gtt gat 403 Lys Lys Gly Gln Ile Ile Ile Asn Ala Ala Arg Gly Gly Leu Val Asp 90 95 100 gag cag gct ttg gct gat gcg att gag tcc ggt cac att cgt ggc gct 451 Glu Gln Ala Leu Ala Asp Ala Ile Glu Ser Gly His Ile Arg Gly Ala 105 110 115 ggt ttc gat gtg tac tcc acc gag cct tgc act gat tct cct ttg ttc 499 Gly Phe Asp Val Tyr Ser Thr Glu Pro Cys Thr Asp Ser Pro Leu Phe 120 125 130 aag ttg cct cag gtt gtt gtg act cct cac ttg ggt gct tct act gaa 547 Lys Leu Pro Gln Val Val Val Thr Pro His Leu Gly Ala Ser Thr Glu 135 140 145 gag gct caa gat cgt gcg ggt act gac att gct gat tct gtg ctc aag 595 Glu Ala Gln Asp Arg Ala Gly Thr Asp Ile Ala Asp Ser Val Leu Lys 150 155 160 165 gcg ctg gct 604 Ala Leu Ala <210> 168 <211> 168 <212> PRT <213> Corynebacterium glutamicum <400> 168 Val Glu Ile Phe Gly Lys Thr Val Gly Ile Val Gly Phe Gly His Ile 1 5 10 15 Gly Gln Leu Phe Ala Gln Arg Leu Ala Ala Phe Glu Thr Thr Ile Val 20 25 30 Ala Tyr Asp Pro Tyr Ala Asn Pro Ala Arg Ala Ala Gln Leu Asn Val 35 40 45 Glu Leu Val Glu Leu Asp Glu Leu Met Ser Arg Ser Asp Phe Val Thr 50 55 60 Ile His Leu Pro Lys Thr Lys Glu Thr Ala Gly Met Phe Asp Ala His 65 70 75 80 Leu Leu Ala Lys Ser Lys Lys Gly Gln Ile Ile Ile Asn Ala Ala Arg 85 90 95 Gly Gly Leu Val Asp Glu Gln Ala Leu Ala Asp Ala Ile Glu Ser Gly 100 105 110 His Ile Arg Gly Ala Gly Phe Asp Val Tyr Ser Thr Glu Pro Cys Thr 115 120 125 Asp Ser Pro Leu Phe Lys Leu Pro Gln Val Val Val Thr Pro His Leu 130 135 140 Gly Ala Ser Thr Glu Glu Ala Gln Asp Arg Ala Gly Thr Asp Ile Ala 145 150 155 160 Asp Ser Val Leu Lys Ala Leu Ala 165 <210> 169 <211> 1458 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1435) <223> RXN00969 <400> 169 ctatagtggc taggtaccct ttttgttttg gacacatgta gggtggccga aacaaagtaa 60 taggacaaca acgctcgacc gcgattattt ttggagaatc atg acc tca gca tct 115 Met Thr Ser Ala Ser 1 5 gcc cca agc ttt aac ccc ggc aag ggt ccc ggc tca gca gtc gga att 163 Ala Pro Ser Phe Asn Pro Gly Lys Gly Pro Gly Ser Ala Val Gly Ile 10 15 20 gcc ctt tta gga ttc gga aca gtc ggc act gag gtg atg cgt ctg atg 211 Ala Leu Leu Gly Phe Gly Thr Val Gly Thr Glu Val Met Arg Leu Met 25 30 35 acc gag tac ggt gat gaa ctt gcg cac cgc att ggt ggc cca ctg gag 259 Thr Glu Tyr Gly Asp Glu Leu Ala His Arg Ile Gly Gly Pro Leu Glu 40 45 50 gtt cgt ggc att gct gtt tct gat atc tca aag cca cgt gaa ggc gtt 307 Val Arg Gly Ile Ala Val Ser Asp Ile Ser Lys Pro Arg Glu Gly Val 55 60 65 gca cct gag ctg ctc act gag gac gct ttt gca ctc atc gag cgc gag 355 Ala Pro Glu Leu Leu Thr Glu Asp Ala Phe Ala Leu Ile Glu Arg Glu 70 75 80 85 gat gtt gac atc gtc gtt gag gtt atc ggc ggc att gag tac cca cgt 403 Asp Val Asp Ile Val Val Glu Val Ile Gly Gly Ile Glu Tyr Pro Arg 90 95 100 gag gta gtt ctc gca gct ctg aag gcc ggc aag tct gtt gtt acc gcc 451 Glu Val Val Leu Ala Ala Leu Lys Ala Gly Lys Ser Val Val Thr Ala 105 110 115 aat aag gct ctt gtt gca gct cac tct gct gag ctt gct gat gca gcg 499 Asn Lys Ala Leu Val Ala Ala His Ser Ala Glu Leu Ala Asp Ala Ala 120 125 130 gaa gcc gca aac gtt gac ctg tac ttc gag gct gct gtt gca tgc gca 547 Glu Ala Ala Asn Val Asp Leu Tyr Phe Glu Ala Ala Val Ala Cys Ala 135 140 145 att cca gtg gtt ggc cca ctg cgt cgc tcc ctg gct ggc gat cag atc 595 Ile Pro Val Val Gly Pro Leu Arg Arg Ser Leu Ala Gly Asp Gln Ile 150 155 160 165 cag tct gtg atg ggc atc gtt aac ggc acc acc aac ttc atc ttg gac 643 Gln Ser Val Met Gly Ile Val Asn Gly Thr Thr Asn Phe Ile Leu Asp 170 175 180 gcc atg gat tcc acc ggc gct gac tat gca gat tct ttg gct gag gca 691 Ala Met Asp Ser Thr Gly Ala Asp Tyr Ala Asp Ser Leu Ala Glu Ala 185 190 195 act cgt ttg ggt tac gcc gaa gct gat cca act gca aac gtc gaa ggc 739 Thr Arg Leu Gly Tyr Ala Glu Ala Asp Pro Thr Ala Asn Val Glu Gly 200 205 210 cat gac gcc gca tcc aag gct gca att ttg gca tgc atc gct ttc cac 787 His Asp Ala Ala Ser Lys Ala Ala Ile Leu Ala Cys Ile Ala Phe His 215 220 225 acc cgt gtt acc gcg gat gat gtg tac tgc gaa ggt att agg aac atc 835 Thr Arg Val Thr Ala Asp Asp Val Tyr Cys Glu Gly Ile Arg Asn Ile 230 235 240 245 aac gct gcc gac att gag gca gca cag cag gca ggc cac acc atc aag 883 Asn Ala Ala Asp Ile Glu Ala Ala Gln Gln Ala Gly His Thr Ile Lys 250 255 260 ttg ttg gcc atc tgt gag aag ttc acc aac aag gaa gga aag tcg gct 931 Leu Leu Ala Ile Cys Glu Lys Phe Thr Asn Lys Glu Gly Lys Ser Ala 265 270 275 att tct gct cgc gtg cac ccg act cta tta cct gtg tcc cac cca ctg 979 Ile Ser Ala Arg Val His Pro Thr Leu Leu Pro Val Ser His Pro Leu 280 285 290 gcg tcg gta aac aag tcc ttt aat gca atc ttt gtt gaa gca gaa gca 1027 Ala Ser Val Asn Lys Ser Phe Asn Ala Ile Phe Val Glu Ala Glu Ala 295 300 305 gct ggt cgc ctg atg ttc tac gga aac ggt gca ggt ggc gcg cca acc 1075 Ala Gly Arg Leu Met Phe Tyr Gly Asn Gly Ala Gly Gly Ala Pro Thr 310 315 320 325 gcg tct gct gtg ctt ggc gac gtc gtt ggt gcc gca cga aac aag gtg 1123 Ala Ser Ala Val Leu Gly Asp Val Val Gly Ala Ala Arg Asn Lys Val 330 335 340 cac ggt ggc cgt gct cca ggt gag tcc acc tac gct aac ctg ccg atc 1171 His Gly Gly Arg Ala Pro Gly Glu Ser Thr Tyr Ala Asn Leu Pro Ile 345 350 355 gct gat ttc ggt gag acc acc act cgt tac cac ctc gac atg gat gtg 1219 Ala Asp Phe Gly Glu Thr Thr Thr Arg Tyr His Leu Asp Met Asp Val 360 365 370 gaa gat cgc gtg ggg gtt ttg gct gaa ttg gct agc ctg ttc tct gag 1267 Glu Asp Arg Val Gly Val Leu Ala Glu Leu Ala Ser Leu Phe Ser Glu 375 380 385 caa gga atc tcc ctg cgt aca atc cga cag gaa gag cgc gat gat gat 1315 Gln Gly Ile Ser Leu Arg Thr Ile Arg Gln Glu Glu Arg Asp Asp Asp 390 395 400 405 gca cgt ctg atc gtg gtc acc cac tct gcg ctg gaa tct gat ctt tcc 1363 Ala Arg Leu Ile Val Val Thr His Ser Ala Leu Glu Ser Asp Leu Ser 410 415 420 cgc acc gtt gaa ctg ctg aag gct aag cct gtt gtt aag gca atc aac 1411 Arg Thr Val Glu Leu Leu Lys Ala Lys Pro Val Val Lys Ala Ile Asn 425 430 435 agt gtg atc cgc ctc gaa agg gac taattttact gacatggcaa ttg 1458 Ser Val Ile Arg Leu Glu Arg Asp 440 445 <210> 170 <211> 445 <212> PRT <213> Corynebacterium glutamicum <400> 170 Met Thr Ser Ala Ser Ala Pro Ser Phe Asn Pro Gly Lys Gly Pro Gly 1 5 10 15 Ser Ala Val Gly Ile Ala Leu Leu Gly Phe Gly Thr Val Gly Thr Glu 20 25 30 Val Met Arg Leu Met Thr Glu Tyr Gly Asp Glu Leu Ala His Arg Ile 35 40 45 Gly Gly Pro Leu Glu Val Arg Gly Ile Ala Val Ser Asp Ile Ser Lys 50 55 60 Pro Arg Glu Gly Val Ala Pro Glu Leu Leu Thr Glu Asp Ala Phe Ala 65 70 75 80 Leu Ile Glu Arg Glu Asp Val Asp Ile Val Val Glu Val Ile Gly Gly 85 90 95 Ile Glu Tyr Pro Arg Glu Val Val Leu Ala Ala Leu Lys Ala Gly Lys 100 105 110 Ser Val Val Thr Ala Asn Lys Ala Leu Val Ala Ala His Ser Ala Glu 115 120 125 Leu Ala Asp Ala Ala Glu Ala Ala Asn Val Asp Leu Tyr Phe Glu Ala 130 135 140 Ala Val Ala Cys Ala Ile Pro Val Val Gly Pro Leu Arg Arg Ser Leu 145 150 155 160 Ala Gly Asp Gln Ile Gln Ser Val Met Gly Ile Val Asn Gly Thr Thr 165 170 175 Asn Phe Ile Leu Asp Ala Met Asp Ser Thr Gly Ala Asp Tyr Ala Asp 180 185 190 Ser Leu Ala Glu Ala Thr Arg Leu Gly Tyr Ala Glu Ala Asp Pro Thr 195 200 205 Ala Asn Val Glu Gly His Asp Ala Ala Ser Lys Ala Ala Ile Leu Ala 210 215 220 Cys Ile Ala Phe His Thr Arg Val Thr Ala Asp Asp Val Tyr Cys Glu 225 230 235 240 Gly Ile Arg Asn Ile Asn Ala Ala Asp Ile Glu Ala Ala Gln Gln Ala 245 250 255 Gly His Thr Ile Lys Leu Leu Ala Ile Cys Glu Lys Phe Thr Asn Lys 260 265 270 Glu Gly Lys Ser Ala Ile Ser Ala Arg Val His Pro Thr Leu Leu Pro 275 280 285 Val Ser His Pro Leu Ala Ser Val Asn Lys Ser Phe Asn Ala Ile Phe 290 295 300 Val Glu Ala Glu Ala Ala Gly Arg Leu Met Phe Tyr Gly Asn Gly Ala 305 310 315 320 Gly Gly Ala Pro Thr Ala Ser Ala Val Leu Gly Asp Val Val Gly Ala 325 330 335 Ala Arg Asn Lys Val His Gly Gly Arg Ala Pro Gly Glu Ser Thr Tyr 340 345 350 Ala Asn Leu Pro Ile Ala Asp Phe Gly Glu Thr Thr Thr Arg Tyr His 355 360 365 Leu Asp Met Asp Val Glu Asp Arg Val Gly Val Leu Ala Glu Leu Ala 370 375 380 Ser Leu Phe Ser Glu Gln Gly Ile Ser Leu Arg Thr Ile Arg Gln Glu 385 390 395 400 Glu Arg Asp Asp Asp Ala Arg Leu Ile Val Val Thr His Ser Ala Leu 405 410 415 Glu Ser Asp Leu Ser Arg Thr Val Glu Leu Leu Lys Ala Lys Pro Val 420 425 430 Val Lys Ala Ile Asn Ser Val Ile Arg Leu Glu Arg Asp 435 440 445 <210> 171 <211> 493 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(493) <223> FRXA00974 <400> 171 ctatagtggc taggtaccct ttttgttttg gacacatgta gggtggccga aacaaagtaa 60 taggacaaca acgctcgacc gcgattattt ttggagaatc atg acc tca gca tct 115 Met Thr Ser Ala Ser 1 5 gcc cca agc ttt aac ccc ggc aag ggt ccc ggc tca gca gtc gga att 163 Ala Pro Ser Phe Asn Pro Gly Lys Gly Pro Gly Ser Ala Val Gly Ile 10 15 20 gcc ctt tta gga ttc gga aca gtc ggc act gag gtg atg cgt ctg atg 211 Ala Leu Leu Gly Phe Gly Thr Val Gly Thr Glu Val Met Arg Leu Met 25 30 35 acc gag tac ggt gat gaa ctt gcg cac cgc att ggt ggc cca ctg gag 259 Thr Glu Tyr Gly Asp Glu Leu Ala His Arg Ile Gly Gly Pro Leu Glu 40 45 50 gtt cgt ggc att gct gtt tct gat atc tca aag cca cgt gaa ggc gtt 307 Val Arg Gly Ile Ala Val Ser Asp Ile Ser Lys Pro Arg Glu Gly Val 55 60 65 gca cct gag ctg ctc act gag gac gct ttt gca ctc atc gag cgc gag 355 Ala Pro Glu Leu Leu Thr Glu Asp Ala Phe Ala Leu Ile Glu Arg Glu 70 75 80 85 gat gtt gac atc gtc gtt gag gtt atc ggc ggc att gag tac cca cgt 403 Asp Val Asp Ile Val Val Glu Val Ile Gly Gly Ile Glu Tyr Pro Arg 90 95 100 gag gta gtt ctc gca gct ctg aag gcc ggc aag tct gtt gtt acc gcc 451 Glu Val Val Leu Ala Ala Leu Lys Ala Gly Lys Ser Val Val Thr Ala 105 110 115 aat aag gct ctt gtt gca gct cac tct gct gag ctt gct gat 493 Asn Lys Ala Leu Val Ala Ala His Ser Ala Glu Leu Ala Asp 120 125 130 <210> 172 <211> 131 <212> PRT <213> Corynebacterium glutamicum <400> 172 Met Thr Ser Ala Ser Ala Pro Ser Phe Asn Pro Gly Lys Gly Pro Gly 1 5 10 15 Ser Ala Val Gly Ile Ala Leu Leu Gly Phe Gly Thr Val Gly Thr Glu 20 25 30 Val Met Arg Leu Met Thr Glu Tyr Gly Asp Glu Leu Ala His Arg Ile 35 40 45 Gly Gly Pro Leu Glu Val Arg Gly Ile Ala Val Ser Asp Ile Ser Lys 50 55 60 Pro Arg Glu Gly Val Ala Pro Glu Leu Leu Thr Glu Asp Ala Phe Ala 65 70 75 80 Leu Ile Glu Arg Glu Asp Val Asp Ile Val Val Glu Val Ile Gly Gly 85 90 95 Ile Glu Tyr Pro Arg Glu Val Val Leu Ala Ala Leu Lys Ala Gly Lys 100 105 110 Ser Val Val Thr Ala Asn Lys Ala Leu Val Ala Ala His Ser Ala Glu 115 120 125 Leu Ala Asp 130 <210> 173 <211> 1050 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1027) <223> RXA00970 <400> 173 gaatctgatc tttcccgcac cgttgaactg ctgaaggcta agcctgttgt taaggcaatc 60 aacagtgtga tccgcctcga aagggactaa ttttactgac atg gca att gaa ctg 115 Met Ala Ile Glu Leu 1 5 aac gtc ggt cgt aag gtt acc gtc acg gta cct gga tct tct gca aac 163 Asn Val Gly Arg Lys Val Thr Val Thr Val Pro Gly Ser Ser Ala Asn 10 15 20 ctc gga cct ggc ttt gac act tta ggt ttg gca ctg tcg gta tac gac 211 Leu Gly Pro Gly Phe Asp Thr Leu Gly Leu Ala Leu Ser Val Tyr Asp 25 30 35 act gtc gaa gtg gaa att att cca tct ggc ttg gaa gtg gaa gtt ttt 259 Thr Val Glu Val Glu Ile Ile Pro Ser Gly Leu Glu Val Glu Val Phe 40 45 50 ggc gaa ggc caa ggc gaa gtc cct ctt gat ggc tcc cac ctg gtg gtt 307 Gly Glu Gly Gln Gly Glu Val Pro Leu Asp Gly Ser His Leu Val Val 55 60 65 aaa gct att cgt gct ggc ctg aag gca gct gac gct gaa gtt cct gga 355 Lys Ala Ile Arg Ala Gly Leu Lys Ala Ala Asp Ala Glu Val Pro Gly 70 75 80 85 ttg cga gtg gtg tgc cac aac aac att ccg cag tct cgt ggt ctt ggc 403 Leu Arg Val Val Cys His Asn Asn Ile Pro Gln Ser Arg Gly Leu Gly 90 95 100 tcc tct gct gca gcg gcg gtt gct ggt gtt gct gca gct aat ggt ttg 451 Ser Ser Ala Ala Ala Ala Val Ala Gly Val Ala Ala Ala Asn Gly Leu 105 110 115 gcg gat ttc ccg ctg act caa gag cag att gtt cag ttg tcc tct gcc 499 Ala Asp Phe Pro Leu Thr Gln Glu Gln Ile Val Gln Leu Ser Ser Ala 120 125 130 ttt gaa ggc cac cca gat aat gct gcg gct tct gtg ctg ggt gga gca 547 Phe Glu Gly His Pro Asp Asn Ala Ala Ala Ser Val Leu Gly Gly Ala 135 140 145 gtg gtg tcg tgg aca aat ctg tct atc gac ggc aag agc cag cca cag 595 Val Val Ser Trp Thr Asn Leu Ser Ile Asp Gly Lys Ser Gln Pro Gln 150 155 160 165 tat gct gct gta cca ctt gag gtg cag gac aat att cgt gcg act gcg 643 Tyr Ala Ala Val Pro Leu Glu Val Gln Asp Asn Ile Arg Ala Thr Ala 170 175 180 ctg gtt cct aat ttc cac gca tcc acc gaa gct gtg cgc cga gtc ctt 691 Leu Val Pro Asn Phe His Ala Ser Thr Glu Ala Val Arg Arg Val Leu 185 190 195 ccc act gaa gtc act cac atc gat gcg cga ttt aac gtg tcc cgc gtt 739 Pro Thr Glu Val Thr His Ile Asp Ala Arg Phe Asn Val Ser Arg Val 200 205 210 gca gtg atg atc gtt gcg ttg cag cag cgt cct gat ttg ctg tgg gag 787 Ala Val Met Ile Val Ala Leu Gln Gln Arg Pro Asp Leu Leu Trp Glu 215 220 225 ggt act cgt gac cgt ctg cac cag cct tat cgt gca gaa gtg ttg cct 835 Gly Thr Arg Asp Arg Leu His Gln Pro Tyr Arg Ala Glu Val Leu Pro 230 235 240 245 att acc tct gag tgg gta aac cgc ctg cgc aac cgt ggc tac gcg gca 883 Ile Thr Ser Glu Trp Val Asn Arg Leu Arg Asn Arg Gly Tyr Ala Ala 250 255 260 tac ctt tcc ggt gcc ggc cca acc gcc atg gtg ctg tcc act gag cca 931 Tyr Leu Ser Gly Ala Gly Pro Thr Ala Met Val Leu Ser Thr Glu Pro 265 270 275 att cca gac aag gtt ttg gaa gat gct cgt gag tct ggc att aag gtg 979 Ile Pro Asp Lys Val Leu Glu Asp Ala Arg Glu Ser Gly Ile Lys Val 280 285 290 ctt gag ctt gag gtt gcg gga cca gtc aag gtt gaa gtt aac caa cct 1027 Leu Glu Leu Glu Val Ala Gly Pro Val Lys Val Glu Val Asn Gln Pro 295 300 305 taggcccaac aaggaaggcc ccc 1050 <210> 174 <211> 309 <212> PRT <213> Corynebacterium glutamicum <400> 174 Met Ala Ile Glu Leu Asn Val Gly Arg Lys Val Thr Val Thr Val Pro 1 5 10 15 Gly Ser Ser Ala Asn Leu Gly Pro Gly Phe Asp Thr Leu Gly Leu Ala 20 25 30 Leu Ser Val Tyr Asp Thr Val Glu Val Glu Ile Ile Pro Ser Gly Leu 35 40 45 Glu Val Glu Val Phe Gly Glu Gly Gln Gly Glu Val Pro Leu Asp Gly 50 55 60 Ser His Leu Val Val Lys Ala Ile Arg Ala Gly Leu Lys Ala Ala Asp 65 70 75 80 Ala Glu Val Pro Gly Leu Arg Val Val Cys His Asn Asn Ile Pro Gln 85 90 95 Ser Arg Gly Leu Gly Ser Ser Ala Ala Ala Ala Val Ala Gly Val Ala 100 105 110 Ala Ala Asn Gly Leu Ala Asp Phe Pro Leu Thr Gln Glu Gln Ile Val 115 120 125 Gln Leu Ser Ser Ala Phe Glu Gly His Pro Asp Asn Ala Ala Ala Ser 130 135 140 Val Leu Gly Gly Ala Val Val Ser Trp Thr Asn Leu Ser Ile Asp Gly 145 150 155 160 Lys Ser Gln Pro Gln Tyr Ala Ala Val Pro Leu Glu Val Gln Asp Asn 165 170 175 Ile Arg Ala Thr Ala Leu Val Pro Asn Phe His Ala Ser Thr Glu Ala 180 185 190 Val Arg Arg Val Leu Pro Thr Glu Val Thr His Ile Asp Ala Arg Phe 195 200 205 Asn Val Ser Arg Val Ala Val Met Ile Val Ala Leu Gln Gln Arg Pro 210 215 220 Asp Leu Leu Trp Glu Gly Thr Arg Asp Arg Leu His Gln Pro Tyr Arg 225 230 235 240 Ala Glu Val Leu Pro Ile Thr Ser Glu Trp Val Asn Arg Leu Arg Asn 245 250 255 Arg Gly Tyr Ala Ala Tyr Leu Ser Gly Ala Gly Pro Thr Ala Met Val 260 265 270 Leu Ser Thr Glu Pro Ile Pro Asp Lys Val Leu Glu Asp Ala Arg Glu 275 280 285 Ser Gly Ile Lys Val Leu Glu Leu Glu Val Ala Gly Pro Val Lys Val 290 295 300 Glu Val Asn Gln Pro 305 <210> 175 <211> 1566 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1543) <223> RXA00330 <400> 175 gcaacacttt agggtatcgc gtgggcgaag tcaccttttt caacatattt gagacggtgt 60 gggggagtat tgtgtcaccc cttgggatag ggttatatcc gtg gac tac att tcg 115 Val Asp Tyr Ile Ser 1 5 acg cgt gat gcc agc cgt acc cct gcc cgc ttc agt gat att ttg ctg 163 Thr Arg Asp Ala Ser Arg Thr Pro Ala Arg Phe Ser Asp Ile Leu Leu 10 15 20 ggc ggt cta gca cca gac ggc gga ctg tac ctg cct gca acc tac cct 211 Gly Gly Leu Ala Pro Asp Gly Gly Leu Tyr Leu Pro Ala Thr Tyr Pro 25 30 35 caa cta gat gat gcc cag ctg agt aaa tgg cgt gag gta tta gcc aac 259 Gln Leu Asp Asp Ala Gln Leu Ser Lys Trp Arg Glu Val Leu Ala Asn 40 45 50 gaa gga tac gca gct ttg gct gct gaa gtt atc tcc ctg ttt gtt gat 307 Glu Gly Tyr Ala Ala Leu Ala Ala Glu Val Ile Ser Leu Phe Val Asp 55 60 65 gac atc cca gta gaa gac atc aag gcg atc acc gca cgc gcc tac acc 355 Asp Ile Pro Val Glu Asp Ile Lys Ala Ile Thr Ala Arg Ala Tyr Thr 70 75 80 85 tac ccg aag ttc aac agc gaa gac atc gtt cct gtc acc gaa ctc gag 403 Tyr Pro Lys Phe Asn Ser Glu Asp Ile Val Pro Val Thr Glu Leu Glu 90 95 100 gac aac att tac ctg ggc cac ctt tcc gaa ggc cca acc gct gca ttc 451 Asp Asn Ile Tyr Leu Gly His Leu Ser Glu Gly Pro Thr Ala Ala Phe 105 110 115 aaa gac atg gcc atg cag ctg ctc ggc gaa ctt ttc gaa tac gag ctt 499 Lys Asp Met Ala Met Gln Leu Leu Gly Glu Leu Phe Glu Tyr Glu Leu 120 125 130 cgc cgc cgc aac gaa acc atc aac atc ctg ggc gct acc tct ggc gat 547 Arg Arg Arg Asn Glu Thr Ile Asn Ile Leu Gly Ala Thr Ser Gly Asp 135 140 145 acc ggc tcc tct gcg gaa tac gcc atg cgc ggc cgc gag gga atc cgc 595 Thr Gly Ser Ser Ala Glu Tyr Ala Met Arg Gly Arg Glu Gly Ile Arg 150 155 160 165 gta ttc atg ctg acc cca gct ggc cgc atg acc cca ttc cag caa gca 643 Val Phe Met Leu Thr Pro Ala Gly Arg Met Thr Pro Phe Gln Gln Ala 170 175 180 cag atg ttt ggc ctt gac gat cca aac atc ttc aac atc gcc ctc gac 691 Gln Met Phe Gly Leu Asp Asp Pro Asn Ile Phe Asn Ile Ala Leu Asp 185 190 195 ggc gtt ttc gac gat tgc caa gac gta gtc aag gct gtc tcc gcc gac 739 Gly Val Phe Asp Asp Cys Gln Asp Val Val Lys Ala Val Ser Ala Asp 200 205 210 gca gaa ttc aaa aaa gac aac cgc atc ggt gcc gtg aac tcc atc aac 787 Ala Glu Phe Lys Lys Asp Asn Arg Ile Gly Ala Val Asn Ser Ile Asn 215 220 225 tgg gca cgc ctt atg gca cag gtt gtg tac tac gtt tcc tca tgg atc 835 Trp Ala Arg Leu Met Ala Gln Val Val Tyr Tyr Val Ser Ser Trp Ile 230 235 240 245 cgc acc aca acc agc aat gac caa aag gtc agc ttc tcc gta cca acc 883 Arg Thr Thr Thr Ser Asn Asp Gln Lys Val Ser Phe Ser Val Pro Thr 250 255 260 ggc aac ttc ggt gac att tgc gca ggc cac atc gcc cgc caa atg gga 931 Gly Asn Phe Gly Asp Ile Cys Ala Gly His Ile Ala Arg Gln Met Gly 265 270 275 ctt ccc atc gat cgc ctc atc gtg gcc acc aac gaa aac gat gtg ctc 979 Leu Pro Ile Asp Arg Leu Ile Val Ala Thr Asn Glu Asn Asp Val Leu 280 285 290 gac gag ttc ttc cgt acc ggc gac tac cga gtc cgc agc tcc gca gac 1027 Asp Glu Phe Phe Arg Thr Gly Asp Tyr Arg Val Arg Ser Ser Ala Asp 295 300 305 acc cac gag acc tcc tca cct tcg atg gat atc tcc cgc gcc tcc aac 1075 Thr His Glu Thr Ser Ser Pro Ser Met Asp Ile Ser Arg Ala Ser Asn 310 315 320 325 ttc gag cgt ttc atc ttc gac ctg ctc ggc cgc gac gcc acc cgc gtc 1123 Phe Glu Arg Phe Ile Phe Asp Leu Leu Gly Arg Asp Ala Thr Arg Val 330 335 340 aac gat cta ttt ggt acc cag gtt cgc caa ggc gga ttc tca ctg gct 1171 Asn Asp Leu Phe Gly Thr Gln Val Arg Gln Gly Gly Phe Ser Leu Ala 345 350 355 gat gac gcc aac ttt gag aag gct gca gca gaa tac ggt ttc gcc tcc 1219 Asp Asp Ala Asn Phe Glu Lys Ala Ala Ala Glu Tyr Gly Phe Ala Ser 360 365 370 gga cga tcc acc cat gct gac cgt gtg gca acc atc gct gac gtg cat 1267 Gly Arg Ser Thr His Ala Asp Arg Val Ala Thr Ile Ala Asp Val His 375 380 385 tcc cgc ctc gac gta cta atc gat ccc cac acc gcc gac ggc gtt cac 1315 Ser Arg Leu Asp Val Leu Ile Asp Pro His Thr Ala Asp Gly Val His 390 395 400 405 gtg gca cgc cag tgg agg gac gag gtc aac acc cca atc atc gtc cta 1363 Val Ala Arg Gln Trp Arg Asp Glu Val Asn Thr Pro Ile Ile Val Leu 410 415 420 gaa act gca ctc cca gtg aaa ttt gcc gac acc atc gtc gaa gca att 1411 Glu Thr Ala Leu Pro Val Lys Phe Ala Asp Thr Ile Val Glu Ala Ile 425 430 435 ggt gaa gca cct caa act cca gag cgt ttc gcc gcg atc atg gat gct 1459 Gly Glu Ala Pro Gln Thr Pro Glu Arg Phe Ala Ala Ile Met Asp Ala 440 445 450 cca ttc aag gtt tcc gac cta cca aac gac acc gat gca gtt aag cag 1507 Pro Phe Lys Val Ser Asp Leu Pro Asn Asp Thr Asp Ala Val Lys Gln 455 460 465 tac ata gtc gat gcg att gca aac act tcc gtg aag taacttgctt 1553 Tyr Ile Val Asp Ala Ile Ala Asn Thr Ser Val Lys 470 475 480 tacgccaagg cct 1566 <210> 176 <211> 481 <212> PRT <213> Corynebacterium glutamicum <400> 176 Val Asp Tyr Ile Ser Thr Arg Asp Ala Ser Arg Thr Pro Ala Arg Phe 1 5 10 15 Ser Asp Ile Leu Leu Gly Gly Leu Ala Pro Asp Gly Gly Leu Tyr Leu 20 25 30 Pro Ala Thr Tyr Pro Gln Leu Asp Asp Ala Gln Leu Ser Lys Trp Arg 35 40 45 Glu Val Leu Ala Asn Glu Gly Tyr Ala Ala Leu Ala Ala Glu Val Ile 50 55 60 Ser Leu Phe Val Asp Asp Ile Pro Val Glu Asp Ile Lys Ala Ile Thr 65 70 75 80 Ala Arg Ala Tyr Thr Tyr Pro Lys Phe Asn Ser Glu Asp Ile Val Pro 85 90 95 Val Thr Glu Leu Glu Asp Asn Ile Tyr Leu Gly His Leu Ser Glu Gly 100 105 110 Pro Thr Ala Ala Phe Lys Asp Met Ala Met Gln Leu Leu Gly Glu Leu 115 120 125 Phe Glu Tyr Glu Leu Arg Arg Arg Asn Glu Thr Ile Asn Ile Leu Gly 130 135 140 Ala Thr Ser Gly Asp Thr Gly Ser Ser Ala Glu Tyr Ala Met Arg Gly 145 150 155 160 Arg Glu Gly Ile Arg Val Phe Met Leu Thr Pro Ala Gly Arg Met Thr 165 170 175 Pro Phe Gln Gln Ala Gln Met Phe Gly Leu Asp Asp Pro Asn Ile Phe 180 185 190 Asn Ile Ala Leu Asp Gly Val Phe Asp Asp Cys Gln Asp Val Val Lys 195 200 205 Ala Val Ser Ala Asp Ala Glu Phe Lys Lys Asp Asn Arg Ile Gly Ala 210 215 220 Val Asn Ser Ile Asn Trp Ala Arg Leu Met Ala Gln Val Val Tyr Tyr 225 230 235 240 Val Ser Ser Trp Ile Arg Thr Thr Thr Ser Asn Asp Gln Lys Val Ser 245 250 255 Phe Ser Val Pro Thr Gly Asn Phe Gly Asp Ile Cys Ala Gly His Ile 260 265 270 Ala Arg Gln Met Gly Leu Pro Ile Asp Arg Leu Ile Val Ala Thr Asn 275 280 285 Glu Asn Asp Val Leu Asp Glu Phe Phe Arg Thr Gly Asp Tyr Arg Val 290 295 300 Arg Ser Ser Ala Asp Thr His Glu Thr Ser Ser Pro Ser Met Asp Ile 305 310 315 320 Ser Arg Ala Ser Asn Phe Glu Arg Phe Ile Phe Asp Leu Leu Gly Arg 325 330 335 Asp Ala Thr Arg Val Asn Asp Leu Phe Gly Thr Gln Val Arg Gln Gly 340 345 350 Gly Phe Ser Leu Ala Asp Asp Ala Asn Phe Glu Lys Ala Ala Ala Glu 355 360 365 Tyr Gly Phe Ala Ser Gly Arg Ser Thr His Ala Asp Arg Val Ala Thr 370 375 380 Ile Ala Asp Val His Ser Arg Leu Asp Val Leu Ile Asp Pro His Thr 385 390 395 400 Ala Asp Gly Val His Val Ala Arg Gln Trp Arg Asp Glu Val Asn Thr 405 410 415 Pro Ile Ile Val Leu Glu Thr Ala Leu Pro Val Lys Phe Ala Asp Thr 420 425 430 Ile Val Glu Ala Ile Gly Glu Ala Pro Gln Thr Pro Glu Arg Phe Ala 435 440 445 Ala Ile Met Asp Ala Pro Phe Lys Val Ser Asp Leu Pro Asn Asp Thr 450 455 460 Asp Ala Val Lys Gln Tyr Ile Val Asp Ala Ile Ala Asn Thr Ser Val 465 470 475 480 Lys <210> 177 <211> 1254 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1231) <223> RXN00403 <400> 177 tttttcagac tcgtgagaat gcaaactaga ctagacagag ctgtccatat acactggacg 60 aagttttagt cttgtccacc cagaacaggc ggttattttc atg ccc acc ctc gcg 115 Met Pro Thr Leu Ala 1 5 cct tca ggt caa ctt gaa atc caa gcg atc ggt gat gtc tcc acc gaa 163 Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly Asp Val Ser Thr Glu 10 15 20 gcc gga gca atc att aca aac gct gaa atc gcc tat cac cgc tgg ggt 211 Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala Tyr His Arg Trp Gly 25 30 35 gaa tac cgc gta gat aaa gaa gga cgc agc aat gtc gtt ctc atc gaa 259 Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn Val Val Leu Ile Glu 40 45 50 cac gcc ctc act gga gat tcc aac gca gcc gat tgg tgg gct gac ttg 307 His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp Trp Trp Ala Asp Leu 55 60 65 ctc ggt ccc ggc aaa gcc atc aac act gat att tac tgc gtg atc tgt 355 Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile Tyr Cys Val Ile Cys 70 75 80 85 acc aac gtc atc ggt ggt tgc aac ggt tcc acc gga cct ggc tcc atg 403 Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr Gly Pro Gly Ser Met 90 95 100 cat cca gat gga aat ttc tgg ggt aat cgc ttc ccc gcc acg tcc att 451 His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe Pro Ala Thr Ser Ile 105 110 115 cgt gat cag gta aac gcc gaa aaa caa ttc ctc gac gca ctc ggc atc 499 Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu Asp Ala Leu Gly Ile 120 125 130 acc acg gtc gcc gca gta ctt ggt ggt tcc atg ggt ggt gcc cgc acc 547 Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met Gly Gly Ala Arg Thr 135 140 145 cta gag tgg gcc gca atg tac cca gaa act gtt ggc gca gct gct gtt 595 Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val Gly Ala Ala Ala Val 150 155 160 165 ctt gca gtt tct gca cgc gcc agc gcc tgg caa atc ggc att caa tcc 643 Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln Ile Gly Ile Gln Ser 170 175 180 gcc caa att aag gcg att gaa aac gac cac cac tgg cac gaa ggc aac 691 Ala Gln Ile Lys Ala Ile Glu Asn Asp His His Trp His Glu Gly Asn 185 190 195 tac tac gaa tcc ggc tgc aac cca gcc acc gga ctc ggc gcc gcc cga 739 Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly Leu Gly Ala Ala Arg 200 205 210 cgc atc gcc cac ctc acc tac cgt ggc gaa cta gaa atc gac gaa cgc 787 Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu Glu Ile Asp Glu Arg 215 220 225 ttc ggc acc aaa gcc caa aag aac gaa aac cca ctc ggt ccc tac cgc 835 Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro Leu Gly Pro Tyr Arg 230 235 240 245 aag ccc gac cag cgc ttc gcc gtg gaa tcc tac ttg gac tac caa gca 883 Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr Leu Asp Tyr Gln Ala 250 255 260 gac aag cta gta cag cgt ttc gac gcc ggc tcc tac gtc ttg ctc acc 931 Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser Tyr Val Leu Leu Thr 265 270 275 gac gcc ctc aac cgc cac gac att ggt cgc gac cgc gga ggc ctc aac 979 Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp Arg Gly Gly Leu Asn 280 285 290 aag gca ctc gaa tcc atc aaa gtt cca gtc ctt gtc gca ggc gta gat 1027 Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu Val Ala Gly Val Asp 295 300 305 acc gat att ttg tac ccc tac cac cag caa gaa cac ctc tcc aga aac 1075 Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu His Leu Ser Arg Asn 310 315 320 325 ctg gga aat cta ctg gca atg gca aaa atc gta tcc cct gtc ggc cac 1123 Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val Ser Pro Val Gly His 330 335 340 gat gct ttc ctc acc gaa agc cgc caa atg gat cgc atc gtg agg aac 1171 Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp Arg Ile Val Arg Asn 345 350 355 ttc ttc agc ctc atc tcc cca gac gaa gac aac cct tcg acc tac atc 1219 Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn Pro Ser Thr Tyr Ile 360 365 370 gag ttc tac atc taataggtat ttacgacaaa tag 1254 Glu Phe Tyr Ile 375 <210> 178 <211> 377 <212> PRT <213> Corynebacterium glutamicum <400> 178 Met Pro Thr Leu Ala Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly 1 5 10 15 Asp Val Ser Thr Glu Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala 20 25 30 Tyr His Arg Trp Gly Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn 35 40 45 Val Val Leu Ile Glu His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp 50 55 60 Trp Trp Ala Asp Leu Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile 65 70 75 80 Tyr Cys Val Ile Cys Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr 85 90 95 Gly Pro Gly Ser Met His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe 100 105 110 Pro Ala Thr Ser Ile Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu 115 120 125 Asp Ala Leu Gly Ile Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met 130 135 140 Gly Gly Ala Arg Thr Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val 145 150 155 160 Gly Ala Ala Ala Val Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln 165 170 175 Ile Gly Ile Gln Ser Ala Gln Ile Lys Ala Ile Glu Asn Asp His His 180 185 190 Trp His Glu Gly Asn Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly 195 200 205 Leu Gly Ala Ala Arg Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu 210 215 220 Glu Ile Asp Glu Arg Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro 225 230 235 240 Leu Gly Pro Tyr Arg Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr 245 250 255 Leu Asp Tyr Gln Ala Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser 260 265 270 Tyr Val Leu Leu Thr Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp 275 280 285 Arg Gly Gly Leu Asn Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu 290 295 300 Val Ala Gly Val Asp Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu 305 310 315 320 His Leu Ser Arg Asn Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val 325 330 335 Ser Pro Val Gly His Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp 340 345 350 Arg Ile Val Arg Asn Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn 355 360 365 Pro Ser Thr Tyr Ile Glu Phe Tyr Ile 370 375 <210> 179 <211> 1210 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1210) <223> FRXA00403 <400> 179 tttttcagac tcgtgagaat gcaaactaga ctagacagag ctgtccatat acactggacg 60 aagttttagt cttgtccacc cagaacaggc ggttattttc atg ccc acc ctc gcg 115 Met Pro Thr Leu Ala 1 5 cct tca ggt caa ctt gaa atc caa gcg atc ggt gat gtc tcc acc gaa 163 Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly Asp Val Ser Thr Glu 10 15 20 gcc gga gca atc att aca aac gct gaa atc gcc tat cac cgc tgg ggt 211 Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala Tyr His Arg Trp Gly 25 30 35 gaa tac cgc gta gat aaa gaa gga cgc agc aat gtc gtt ctc atc gaa 259 Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn Val Val Leu Ile Glu 40 45 50 cac gcc ctc act gga gat tcc aac gca gcc gat tgg tgg gct gac ttg 307 His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp Trp Trp Ala Asp Leu 55 60 65 ctc ggt ccc ggc aaa gcc atc aac act gat att tac tgc gtg atc tgt 355 Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile Tyr Cys Val Ile Cys 70 75 80 85 acc aac gtc atc ggt ggt tgc aac ggt tcc acc gga cct ggc tcc atg 403 Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr Gly Pro Gly Ser Met 90 95 100 cat cca gat gga aat ttc tgg ggt aat cgc ttc ccc gcc acg tcc att 451 His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe Pro Ala Thr Ser Ile 105 110 115 cgt gat cag gta aac gcc gaa aaa caa ttc ctc gac gca ctc ggc atc 499 Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu Asp Ala Leu Gly Ile 120 125 130 acc acg gtc gcc gca gta ctt ggt ggt tcc atg ggt ggt gcc cgc acc 547 Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met Gly Gly Ala Arg Thr 135 140 145 cta gag tgg gcc gca atg tac cca gaa act gtt ggc gca gct gct gtt 595 Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val Gly Ala Ala Ala Val 150 155 160 165 ctt gca gtt tct gca cgc gcc agc gcc tgg caa atc ggc att caa tcc 643 Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln Ile Gly Ile Gln Ser 170 175 180 gcc caa att aag gcg att gaa aac gac cac cac tgg cac gaa ggc aac 691 Ala Gln Ile Lys Ala Ile Glu Asn Asp His His Trp His Glu Gly Asn 185 190 195 tac tac gaa tcc ggc tgc aac cca gcc acc gga ctc ggc gcc gcc cga 739 Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly Leu Gly Ala Ala Arg 200 205 210 cgc atc gcc cac ctc acc tac cgt ggc gaa cta gaa atc gac gaa cgc 787 Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu Glu Ile Asp Glu Arg 215 220 225 ttc ggc acc aaa gcc caa aag aac gaa aac cca ctc ggt ccc tac cgc 835 Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro Leu Gly Pro Tyr Arg 230 235 240 245 aag ccc gac cag cgc ttc gcc gtg gaa tcc tac ttg gac tac caa gca 883 Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr Leu Asp Tyr Gln Ala 250 255 260 gac aag cta gta cag cgt ttc gac gcc ggc tcc tac gtc ttg ctc acc 931 Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser Tyr Val Leu Leu Thr 265 270 275 gac gcc ctc aac cgc cac gac att ggt cgc gac cgc gga ggc ctc aac 979 Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp Arg Gly Gly Leu Asn 280 285 290 aag gca ctc gaa tcc atc aaa gtt cca gtc ctt gtc gca ggc gta gat 1027 Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu Val Ala Gly Val Asp 295 300 305 acc gat att ttg tac ccc tac cac cag caa gaa cac ctc tcc aga aac 1075 Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu His Leu Ser Arg Asn 310 315 320 325 ctg gga aat cta ctg gca atg gca aaa atc gta tcc cct gtc ggc cac 1123 Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val Ser Pro Val Gly His 330 335 340 gat gct ttc ctc acc gaa agc cgc caa atg gat cgc atc gtg agg aac 1171 Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp Arg Ile Val Arg Asn 345 350 355 ttc ttc agc ctc atc tcc cca gac gaa gac aac cct tcg 1210 Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn Pro Ser 360 365 370 <210> 180 <211> 370 <212> PRT <213> Corynebacterium glutamicum <400> 180 Met Pro Thr Leu Ala Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly 1 5 10 15 Asp Val Ser Thr Glu Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala 20 25 30 Tyr His Arg Trp Gly Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn 35 40 45 Val Val Leu Ile Glu His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp 50 55 60 Trp Trp Ala Asp Leu Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile 65 70 75 80 Tyr Cys Val Ile Cys Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr 85 90 95 Gly Pro Gly Ser Met His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe 100 105 110 Pro Ala Thr Ser Ile Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu 115 120 125 Asp Ala Leu Gly Ile Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met 130 135 140 Gly Gly Ala Arg Thr Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val 145 150 155 160 Gly Ala Ala Ala Val Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln 165 170 175 Ile Gly Ile Gln Ser Ala Gln Ile Lys Ala Ile Glu Asn Asp His His 180 185 190 Trp His Glu Gly Asn Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly 195 200 205 Leu Gly Ala Ala Arg Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu 210 215 220 Glu Ile Asp Glu Arg Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro 225 230 235 240 Leu Gly Pro Tyr Arg Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr 245 250 255 Leu Asp Tyr Gln Ala Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser 260 265 270 Tyr Val Leu Leu Thr Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp 275 280 285 Arg Gly Gly Leu Asn Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu 290 295 300 Val Ala Gly Val Asp Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu 305 310 315 320 His Leu Ser Arg Asn Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val 325 330 335 Ser Pro Val Gly His Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp 340 345 350 Arg Ile Val Arg Asn Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn 355 360 365 Pro Ser 370 <210> 181 <211> 771 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(748) <223> RXC01207 <400> 181 cttcatgatc tcaccggcag agcgcgtttt gttacagcgc gtaaactgtg actttgaaaa 60 atttttgaac aatccgtaca ccaacttcag gagaaaaaca gtg agc aga atc tat 115 Val Ser Arg Ile Tyr 1 5 gac tgt gcc gac caa gac tcc cgt gca gca ggc cta aag gcg gct gtc 163 Asp Cys Ala Asp Gln Asp Ser Arg Ala Ala Gly Leu Lys Ala Ala Val 10 15 20 gat gca gtc aaa gcc ggt cag ctc gtt gtc ctt ccc acg gat acc ctt 211 Asp Ala Val Lys Ala Gly Gln Leu Val Val Leu Pro Thr Asp Thr Leu 25 30 35 tat gga ctc ggc tgc gac gct ttc aac aac gag gca gta gcc aac ctt 259 Tyr Gly Leu Gly Cys Asp Ala Phe Asn Asn Glu Ala Val Ala Asn Leu 40 45 50 ctg gcc acc aaa cac cgt ggc ccc gat atg ccc gtt cca gtg ctc gtc 307 Leu Ala Thr Lys His Arg Gly Pro Asp Met Pro Val Pro Val Leu Val 55 60 65 ggc agc tgg gac acc att caa gga ctt gtg cac tcc tat tct gcg cag 355 Gly Ser Trp Asp Thr Ile Gln Gly Leu Val His Ser Tyr Ser Ala Gln 70 75 80 85 gca aaa gcg ctt gtg gag gcg ttc tgg cct ggt gga ctg tcc atc atc 403 Ala Lys Ala Leu Val Glu Ala Phe Trp Pro Gly Gly Leu Ser Ile Ile 90 95 100 gtt ccg cag gca cca agc ctt ccg tgg aac ctt ggc gat acc cgt ggc 451 Val Pro Gln Ala Pro Ser Leu Pro Trp Asn Leu Gly Asp Thr Arg Gly 105 110 115 acc gta atg ctg cgc atg cca ctg cac cca gtt gcc att gaa ttg ctg 499 Thr Val Met Leu Arg Met Pro Leu His Pro Val Ala Ile Glu Leu Leu 120 125 130 cgc caa acc gga cca atg gct gtc tcc tcc gcc aac atc tcc gga cat 547 Arg Gln Thr Gly Pro Met Ala Val Ser Ser Ala Asn Ile Ser Gly His 135 140 145 act cct cca acc acc gtg ctg gag gct cgt cag cag ctc aac caa aat 595 Thr Pro Pro Thr Thr Val Leu Glu Ala Arg Gln Gln Leu Asn Gln Asn 150 155 160 165 gtc gct gtc tac ctc gat ggt ggc gaa tgc gcg ctg gcc acc cct tca 643 Val Ala Val Tyr Leu Asp Gly Gly Glu Cys Ala Leu Ala Thr Pro Ser 170 175 180 acc atc gtg gat att tca ggc ccc gca cca aag att ttg cgt gag ggt 691 Thr Ile Val Asp Ile Ser Gly Pro Ala Pro Lys Ile Leu Arg Glu Gly 185 190 195 gcc atc agc gca gaa cgc gtt ggc gaa gta ctt gga gtg tcg gca gaa 739 Ala Ile Ser Ala Glu Arg Val Gly Glu Val Leu Gly Val Ser Ala Glu 200 205 210 agc ctg cgc taaatgggag tcggtttcgc ggg 771 Ser Leu Arg 215 <210> 182 <211> 216 <212> PRT <213> Corynebacterium glutamicum <400> 182 Val Ser Arg Ile Tyr Asp Cys Ala Asp Gln Asp Ser Arg Ala Ala Gly 1 5 10 15 Leu Lys Ala Ala Val Asp Ala Val Lys Ala Gly Gln Leu Val Val Leu 20 25 30 Pro Thr Asp Thr Leu Tyr Gly Leu Gly Cys Asp Ala Phe Asn Asn Glu 35 40 45 Ala Val Ala Asn Leu Leu Ala Thr Lys His Arg Gly Pro Asp Met Pro 50 55 60 Val Pro Val Leu Val Gly Ser Trp Asp Thr Ile Gln Gly Leu Val His 65 70 75 80 Ser Tyr Ser Ala Gln Ala Lys Ala Leu Val Glu Ala Phe Trp Pro Gly 85 90 95 Gly Leu Ser Ile Ile Val Pro Gln Ala Pro Ser Leu Pro Trp Asn Leu 100 105 110 Gly Asp Thr Arg Gly Thr Val Met Leu Arg Met Pro Leu His Pro Val 115 120 125 Ala Ile Glu Leu Leu Arg Gln Thr Gly Pro Met Ala Val Ser Ser Ala 130 135 140 Asn Ile Ser Gly His Thr Pro Pro Thr Thr Val Leu Glu Ala Arg Gln 145 150 155 160 Gln Leu Asn Gln Asn Val Ala Val Tyr Leu Asp Gly Gly Glu Cys Ala 165 170 175 Leu Ala Thr Pro Ser Thr Ile Val Asp Ile Ser Gly Pro Ala Pro Lys 180 185 190 Ile Leu Arg Glu Gly Ala Ile Ser Ala Glu Arg Val Gly Glu Val Leu 195 200 205 Gly Val Ser Ala Glu Ser Leu Arg 210 215 <210> 183 <211> 1419 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1396) <223> RXC00152 <400> 183 gtcattgata tccaaggcac gaccgcgatt gtatggaaag aagcctaaat ttttaacaat 60 caaatagtac tggccattcc caactaaaac tggagtaacg atg aca gga cta atc 115 Met Thr Gly Leu Ile 1 5 ctc gcc ata gtt ttc ctg gtc ttt gtc gcc gtc gtg gtg atc aag tcc 163 Leu Ala Ile Val Phe Leu Val Phe Val Ala Val Val Val Ile Lys Ser 10 15 20 ata gcc ctg att ccc cag ggt gaa gcc gcc gtc att gaa cgc ctt ggt 211 Ile Ala Leu Ile Pro Gln Gly Glu Ala Ala Val Ile Glu Arg Leu Gly 25 30 35 agc tac acc cgc acc gtt tca ggt ggc ctg acc ctg ctg gtt cca ttc 259 Ser Tyr Thr Arg Thr Val Ser Gly Gly Leu Thr Leu Leu Val Pro Phe 40 45 50 gtg gac cga gta cgc gca agg atc gac acc cgt gag cgc gtg gtc tca 307 Val Asp Arg Val Arg Ala Arg Ile Asp Thr Arg Glu Arg Val Val Ser 55 60 65 ttc cca ccg cag gct gtt att acc caa gac aac ctg acc gtg gcc atc 355 Phe Pro Pro Gln Ala Val Ile Thr Gln Asp Asn Leu Thr Val Ala Ile 70 75 80 85 gat atc gtg gtg acc ttc caa atc aac gaa cca gag cgc gcc atc tac 403 Asp Ile Val Val Thr Phe Gln Ile Asn Glu Pro Glu Arg Ala Ile Tyr 90 95 100 ggc gtg gac aac tac atc gtc ggt gtg gag cag att tct gta gca aca 451 Gly Val Asp Asn Tyr Ile Val Gly Val Glu Gln Ile Ser Val Ala Thr 105 110 115 ctt cga gac gtt gtc ggt ggc atg acc ctg gaa gaa acc ctc act tca 499 Leu Arg Asp Val Val Gly Gly Met Thr Leu Glu Glu Thr Leu Thr Ser 120 125 130 cgt gac gtg atc aac cgc cgc ctc cgt ggc gag ctc gat gca gca acc 547 Arg Asp Val Ile Asn Arg Arg Leu Arg Gly Glu Leu Asp Ala Ala Thr 135 140 145 acc aaa tgg ggc ctg cgc atc agc cgt gtg gaa cta aag gca att gat 595 Thr Lys Trp Gly Leu Arg Ile Ser Arg Val Glu Leu Lys Ala Ile Asp 150 155 160 165 ccg cca cca tcc atc cag caa tcg atg gaa aag cag atg aag gca gac 643 Pro Pro Pro Ser Ile Gln Gln Ser Met Glu Lys Gln Met Lys Ala Asp 170 175 180 cgt gaa aag cgc gcc acc att ttg acc gca gaa ggt cag cgc gaa gcc 691 Arg Glu Lys Arg Ala Thr Ile Leu Thr Ala Glu Gly Gln Arg Glu Ala 185 190 195 gac atc aaa act gcc gaa ggt gaa aag caa gcc aag atc ctc caa gct 739 Asp Ile Lys Thr Ala Glu Gly Glu Lys Gln Ala Lys Ile Leu Gln Ala 200 205 210 gag ggt gaa aag cac gca tcc atc ctg aac gca gaa gca gaa cgc caa 787 Glu Gly Glu Lys His Ala Ser Ile Leu Asn Ala Glu Ala Glu Arg Gln 215 220 225 gcg atg atc ctg cgc gcc gaa ggt gaa cgc gca gca cgc tac ctc cag 835 Ala Met Ile Leu Arg Ala Glu Gly Glu Arg Ala Ala Arg Tyr Leu Gln 230 235 240 245 gcg cag ggt gaa gcc cga gca atc caa aag gtc aac gca gca atc aag 883 Ala Gln Gly Glu Ala Arg Ala Ile Gln Lys Val Asn Ala Ala Ile Lys 250 255 260 tct gcc aag ttg acc cca gag gtt ctt gct tat caa tac ctc gaa aag 931 Ser Ala Lys Leu Thr Pro Glu Val Leu Ala Tyr Gln Tyr Leu Glu Lys 265 270 275 ctt cct aag atc gca gag ggc aac gcc tcc aag atg tgg gtc atc cca 979 Leu Pro Lys Ile Ala Glu Gly Asn Ala Ser Lys Met Trp Val Ile Pro 280 285 290 agc cag ttc tcc gat tct ctg gaa ggt ttt gcg aag cag ttc ggc gca 1027 Ser Gln Phe Ser Asp Ser Leu Glu Gly Phe Ala Lys Gln Phe Gly Ala 295 300 305 aag gat gca gaa ggt gtc ttc cgc tac gaa cca aac acc gtg gat gaa 1075 Lys Asp Ala Glu Gly Val Phe Arg Tyr Glu Pro Asn Thr Val Asp Glu 310 315 320 325 gaa acc cgc gac atc gca aac gcc gac aac gtg gaa gac tgg ttc tcc 1123 Glu Thr Arg Asp Ile Ala Asn Ala Asp Asn Val Glu Asp Trp Phe Ser 330 335 340 acc gaa tca gac cct gaa atc gca gca gca gtc gcc gca gca aac gcc 1171 Thr Glu Ser Asp Pro Glu Ile Ala Ala Ala Val Ala Ala Ala Asn Ala 345 350 355 gtg gcc aac aag cca gtc gat cca gaa ccc ggt gag atc ctt tcc aag 1219 Val Ala Asn Lys Pro Val Asp Pro Glu Pro Gly Glu Ile Leu Ser Lys 360 365 370 aag acc gca cga cgc gtt gaa cct gaa gca gta ttg gag gct ttg caa 1267 Lys Thr Ala Arg Arg Val Glu Pro Glu Ala Val Leu Glu Ala Leu Gln 375 380 385 aac gga acc act aca caa cct gag gtt gag gca gca cct cct acc gca 1315 Asn Gly Thr Thr Thr Gln Pro Glu Val Glu Ala Ala Pro Pro Thr Ala 390 395 400 405 aac ttc gcc caa gaa ttc cct gca cca cag gca aac cct gaa gat tac 1363 Asn Phe Ala Gln Glu Phe Pro Ala Pro Gln Ala Asn Pro Glu Asp Tyr 410 415 420 tcc gac caa cac cga gag aat cct tac gga aac taatcaggca taagaaaagg 1416 Ser Asp Gln His Arg Glu Asn Pro Tyr Gly Asn 425 430 cgg 1419 <210> 184 <211> 432 <212> PRT <213> Corynebacterium glutamicum <400> 184 Met Thr Gly Leu Ile Leu Ala Ile Val Phe Leu Val Phe Val Ala Val 1 5 10 15 Val Val Ile Lys Ser Ile Ala Leu Ile Pro Gln Gly Glu Ala Ala Val 20 25 30 Ile Glu Arg Leu Gly Ser Tyr Thr Arg Thr Val Ser Gly Gly Leu Thr 35 40 45 Leu Leu Val Pro Phe Val Asp Arg Val Arg Ala Arg Ile Asp Thr Arg 50 55 60 Glu Arg Val Val Ser Phe Pro Pro Gln Ala Val Ile Thr Gln Asp Asn 65 70 75 80 Leu Thr Val Ala Ile Asp Ile Val Val Thr Phe Gln Ile Asn Glu Pro 85 90 95 Glu Arg Ala Ile Tyr Gly Val Asp Asn Tyr Ile Val Gly Val Glu Gln 100 105 110 Ile Ser Val Ala Thr Leu Arg Asp Val Val Gly Gly Met Thr Leu Glu 115 120 125 Glu Thr Leu Thr Ser Arg Asp Val Ile Asn Arg Arg Leu Arg Gly Glu 130 135 140 Leu Asp Ala Ala Thr Thr Lys Trp Gly Leu Arg Ile Ser Arg Val Glu 145 150 155 160 Leu Lys Ala Ile Asp Pro Pro Pro Ser Ile Gln Gln Ser Met Glu Lys 165 170 175 Gln Met Lys Ala Asp Arg Glu Lys Arg Ala Thr Ile Leu Thr Ala Glu 180 185 190 Gly Gln Arg Glu Ala Asp Ile Lys Thr Ala Glu Gly Glu Lys Gln Ala 195 200 205 Lys Ile Leu Gln Ala Glu Gly Glu Lys His Ala Ser Ile Leu Asn Ala 210 215 220 Glu Ala Glu Arg Gln Ala Met Ile Leu Arg Ala Glu Gly Glu Arg Ala 225 230 235 240 Ala Arg Tyr Leu Gln Ala Gln Gly Glu Ala Arg Ala Ile Gln Lys Val 245 250 255 Asn Ala Ala Ile Lys Ser Ala Lys Leu Thr Pro Glu Val Leu Ala Tyr 260 265 270 Gln Tyr Leu Glu Lys Leu Pro Lys Ile Ala Glu Gly Asn Ala Ser Lys 275 280 285 Met Trp Val Ile Pro Ser Gln Phe Ser Asp Ser Leu Glu Gly Phe Ala 290 295 300 Lys Gln Phe Gly Ala Lys Asp Ala Glu Gly Val Phe Arg Tyr Glu Pro 305 310 315 320 Asn Thr Val Asp Glu Glu Thr Arg Asp Ile Ala Asn Ala Asp Asn Val 325 330 335 Glu Asp Trp Phe Ser Thr Glu Ser Asp Pro Glu Ile Ala Ala Ala Val 340 345 350 Ala Ala Ala Asn Ala Val Ala Asn Lys Pro Val Asp Pro Glu Pro Gly 355 360 365 Glu Ile Leu Ser Lys Lys Thr Ala Arg Arg Val Glu Pro Glu Ala Val 370 375 380 Leu Glu Ala Leu Gln Asn Gly Thr Thr Thr Gln Pro Glu Val Glu Ala 385 390 395 400 Ala Pro Pro Thr Ala Asn Phe Ala Gln Glu Phe Pro Ala Pro Gln Ala 405 410 415 Asn Pro Glu Asp Tyr Ser Asp Gln His Arg Glu Asn Pro Tyr Gly Asn 420 425 430 <210> 185 <211> 1170 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1147) <223> RXA00115 <400> 185 tggattctcg agtctgtaca cccttgatca aagcccgagt gttccgtaga ttaactttgt 60 cgtatattgt gacctacacc ccatactgtt aggagttttc atg ctc gac aat agt 115 Met Leu Asp Asn Ser 1 5 ttt tac acc gca gag gtt cag ggc cca tac gaa acc gct tcc att ggc 163 Phe Tyr Thr Ala Glu Val Gln Gly Pro Tyr Glu Thr Ala Ser Ile Gly 10 15 20 cgg ctc gaa ctc gaa gaa ggg ggt gtg att gag gat tgc tgg ttg gct 211 Arg Leu Glu Leu Glu Glu Gly Gly Val Ile Glu Asp Cys Trp Leu Ala 25 30 35 tac gct aca gct gga acg ctc aac gag gac aag tcc aac gcc atc ctc 259 Tyr Ala Thr Ala Gly Thr Leu Asn Glu Asp Lys Ser Asn Ala Ile Leu 40 45 50 att ccg acg tgg tac tcc gga acc cat cag acc tgg ttc cag cag tac 307 Ile Pro Thr Trp Tyr Ser Gly Thr His Gln Thr Trp Phe Gln Gln Tyr 55 60 65 atc ggc act gat cat gcg ctg gat cca tca aag tat ttc atc atc tcc 355 Ile Gly Thr Asp His Ala Leu Asp Pro Ser Lys Tyr Phe Ile Ile Ser 70 75 80 85 atc aac caa atc ggt aat ggt ttg tcg gtc tcc cct gcc aac acg gct 403 Ile Asn Gln Ile Gly Asn Gly Leu Ser Val Ser Pro Ala Asn Thr Ala 90 95 100 gat gac agc atc tcg atg tcc aag ttc ccg aat gtt cgc att ggt gat 451 Asp Asp Ser Ile Ser Met Ser Lys Phe Pro Asn Val Arg Ile Gly Asp 105 110 115 gat gtc gtt gcc cag gac cgg ctc ttg cgc caa gag ttt ggt att acc 499 Asp Val Val Ala Gln Asp Arg Leu Leu Arg Gln Glu Phe Gly Ile Thr 120 125 130 gag ctc ttt gcc gtc gtt ggt ggt tcg atg ggt gcg cag caa acc tat 547 Glu Leu Phe Ala Val Val Gly Gly Ser Met Gly Ala Gln Gln Thr Tyr 135 140 145 gag tgg att gtt cgc ttc cct gac caa gtt cat cga gca gct ccg atc 595 Glu Trp Ile Val Arg Phe Pro Asp Gln Val His Arg Ala Ala Pro Ile 150 155 160 165 gcg ggc act gcg aag aac act cct cat gat ttc atc ttc acc cag act 643 Ala Gly Thr Ala Lys Asn Thr Pro His Asp Phe Ile Phe Thr Gln Thr 170 175 180 ctt aat gag acc gtt gag gcc gat cca ggg ttc aat ggc ggc gaa tac 691 Leu Asn Glu Thr Val Glu Ala Asp Pro Gly Phe Asn Gly Gly Glu Tyr 185 190 195 tcc tcc cat gaa gag gta gct gat gga ctt cgc cgt caa tcg cat ctt 739 Ser Ser His Glu Glu Val Ala Asp Gly Leu Arg Arg Gln Ser His Leu 200 205 210 tgg gct gcc atg gga ttt tcc aca gag ttc tgg aag cag gag gca tgg 787 Trp Ala Ala Met Gly Phe Ser Thr Glu Phe Trp Lys Gln Glu Ala Trp 215 220 225 cgt cgc ctg gga ctt gaa agt aag gag tca gtg ctc gcg gac ttc ctg 835 Arg Arg Leu Gly Leu Glu Ser Lys Glu Ser Val Leu Ala Asp Phe Leu 230 235 240 245 gat ccg ctg ttc atg tcc atg gat cct aat acc ttg ctc aac aac gct 883 Asp Pro Leu Phe Met Ser Met Asp Pro Asn Thr Leu Leu Asn Asn Ala 250 255 260 tgg aag tgg cag cat ggc gat gtc tct cgc cac acc ggc ggc gac ttg 931 Trp Lys Trp Gln His Gly Asp Val Ser Arg His Thr Gly Gly Asp Leu 265 270 275 gca gcg gct ctt ggc cga gtg aag gct aag acc ttc gtt atg ccc atc 979 Ala Ala Ala Leu Gly Arg Val Lys Ala Lys Thr Phe Val Met Pro Ile 280 285 290 agc gag gac atg ttc ttt cct gtt cgt gac tgt gcc gca gaa caa gca 1027 Ser Glu Asp Met Phe Phe Pro Val Arg Asp Cys Ala Ala Glu Gln Ala 295 300 305 ctc atc cca ggc agc gag ctt cga gtg atc gaa gac atc gcc ggt cac 1075 Leu Ile Pro Gly Ser Glu Leu Arg Val Ile Glu Asp Ile Ala Gly His 310 315 320 325 ctt ggg ctt ttt aac gtc tct gag aat tac atc cca cag atc gac aaa 1123 Leu Gly Leu Phe Asn Val Ser Glu Asn Tyr Ile Pro Gln Ile Asp Lys 330 335 340 aat ctg aaa gag ctg ttc gag agc taaacactga tgtcaaagag cct 1170 Asn Leu Lys Glu Leu Phe Glu Ser 345 <210> 186 <211> 349 <212> PRT <213> Corynebacterium glutamicum <400> 186 Met Leu Asp Asn Ser Phe Tyr Thr Ala Glu Val Gln Gly Pro Tyr Glu 1 5 10 15 Thr Ala Ser Ile Gly Arg Leu Glu Leu Glu Glu Gly Gly Val Ile Glu 20 25 30 Asp Cys Trp Leu Ala Tyr Ala Thr Ala Gly Thr Leu Asn Glu Asp Lys 35 40 45 Ser Asn Ala Ile Leu Ile Pro Thr Trp Tyr Ser Gly Thr His Gln Thr 50 55 60 Trp Phe Gln Gln Tyr Ile Gly Thr Asp His Ala Leu Asp Pro Ser Lys 65 70 75 80 Tyr Phe Ile Ile Ser Ile Asn Gln Ile Gly Asn Gly Leu Ser Val Ser 85 90 95 Pro Ala Asn Thr Ala Asp Asp Ser Ile Ser Met Ser Lys Phe Pro Asn 100 105 110 Val Arg Ile Gly Asp Asp Val Val Ala Gln Asp Arg Leu Leu Arg Gln 115 120 125 Glu Phe Gly Ile Thr Glu Leu Phe Ala Val Val Gly Gly Ser Met Gly 130 135 140 Ala Gln Gln Thr Tyr Glu Trp Ile Val Arg Phe Pro Asp Gln Val His 145 150 155 160 Arg Ala Ala Pro Ile Ala Gly Thr Ala Lys Asn Thr Pro His Asp Phe 165 170 175 Ile Phe Thr Gln Thr Leu Asn Glu Thr Val Glu Ala Asp Pro Gly Phe 180 185 190 Asn Gly Gly Glu Tyr Ser Ser His Glu Glu Val Ala Asp Gly Leu Arg 195 200 205 Arg Gln Ser His Leu Trp Ala Ala Met Gly Phe Ser Thr Glu Phe Trp 210 215 220 Lys Gln Glu Ala Trp Arg Arg Leu Gly Leu Glu Ser Lys Glu Ser Val 225 230 235 240 Leu Ala Asp Phe Leu Asp Pro Leu Phe Met Ser Met Asp Pro Asn Thr 245 250 255 Leu Leu Asn Asn Ala Trp Lys Trp Gln His Gly Asp Val Ser Arg His 260 265 270 Thr Gly Gly Asp Leu Ala Ala Ala Leu Gly Arg Val Lys Ala Lys Thr 275 280 285 Phe Val Met Pro Ile Ser Glu Asp Met Phe Phe Pro Val Arg Asp Cys 290 295 300 Ala Ala Glu Gln Ala Leu Ile Pro Gly Ser Glu Leu Arg Val Ile Glu 305 310 315 320 Asp Ile Ala Gly His Leu Gly Leu Phe Asn Val Ser Glu Asn Tyr Ile 325 330 335 Pro Gln Ile Asp Lys Asn Leu Lys Glu Leu Phe Glu Ser 340 345 <210> 187 <211> 1254 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1231) <223> RXN00403 <400> 187 tttttcagac tcgtgagaat gcaaactaga ctagacagag ctgtccatat acactggacg 60 aagttttagt cttgtccacc cagaacaggc ggttattttc atg ccc acc ctc gcg 115 Met Pro Thr Leu Ala 1 5 cct tca ggt caa ctt gaa atc caa gcg atc ggt gat gtc tcc acc gaa 163 Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly Asp Val Ser Thr Glu 10 15 20 gcc gga gca atc att aca aac gct gaa atc gcc tat cac cgc tgg ggt 211 Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala Tyr His Arg Trp Gly 25 30 35 gaa tac cgc gta gat aaa gaa gga cgc agc aat gtc gtt ctc atc gaa 259 Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn Val Val Leu Ile Glu 40 45 50 cac gcc ctc act gga gat tcc aac gca gcc gat tgg tgg gct gac ttg 307 His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp Trp Trp Ala Asp Leu 55 60 65 ctc ggt ccc ggc aaa gcc atc aac act gat att tac tgc gtg atc tgt 355 Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile Tyr Cys Val Ile Cys 70 75 80 85 acc aac gtc atc ggt ggt tgc aac ggt tcc acc gga cct ggc tcc atg 403 Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr Gly Pro Gly Ser Met 90 95 100 cat cca gat gga aat ttc tgg ggt aat cgc ttc ccc gcc acg tcc att 451 His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe Pro Ala Thr Ser Ile 105 110 115 cgt gat cag gta aac gcc gaa aaa caa ttc ctc gac gca ctc ggc atc 499 Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu Asp Ala Leu Gly Ile 120 125 130 acc acg gtc gcc gca gta ctt ggt ggt tcc atg ggt ggt gcc cgc acc 547 Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met Gly Gly Ala Arg Thr 135 140 145 cta gag tgg gcc gca atg tac cca gaa act gtt ggc gca gct gct gtt 595 Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val Gly Ala Ala Ala Val 150 155 160 165 ctt gca gtt tct gca cgc gcc agc gcc tgg caa atc ggc att caa tcc 643 Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln Ile Gly Ile Gln Ser 170 175 180 gcc caa att aag gcg att gaa aac gac cac cac tgg cac gaa ggc aac 691 Ala Gln Ile Lys Ala Ile Glu Asn Asp His His Trp His Glu Gly Asn 185 190 195 tac tac gaa tcc ggc tgc aac cca gcc acc gga ctc ggc gcc gcc cga 739 Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly Leu Gly Ala Ala Arg 200 205 210 cgc atc gcc cac ctc acc tac cgt ggc gaa cta gaa atc gac gaa cgc 787 Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu Glu Ile Asp Glu Arg 215 220 225 ttc ggc acc aaa gcc caa aag aac gaa aac cca ctc ggt ccc tac cgc 835 Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro Leu Gly Pro Tyr Arg 230 235 240 245 aag ccc gac cag cgc ttc gcc gtg gaa tcc tac ttg gac tac caa gca 883 Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr Leu Asp Tyr Gln Ala 250 255 260 gac aag cta gta cag cgt ttc gac gcc ggc tcc tac gtc ttg ctc acc 931 Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser Tyr Val Leu Leu Thr 265 270 275 gac gcc ctc aac cgc cac gac att ggt cgc gac cgc gga ggc ctc aac 979 Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp Arg Gly Gly Leu Asn 280 285 290 aag gca ctc gaa tcc atc aaa gtt cca gtc ctt gtc gca ggc gta gat 1027 Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu Val Ala Gly Val Asp 295 300 305 acc gat att ttg tac ccc tac cac cag caa gaa cac ctc tcc aga aac 1075 Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu His Leu Ser Arg Asn 310 315 320 325 ctg gga aat cta ctg gca atg gca aaa atc gta tcc cct gtc ggc cac 1123 Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val Ser Pro Val Gly His 330 335 340 gat gct ttc ctc acc gaa agc cgc caa atg gat cgc atc gtg agg aac 1171 Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp Arg Ile Val Arg Asn 345 350 355 ttc ttc agc ctc atc tcc cca gac gaa gac aac cct tcg acc tac atc 1219 Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn Pro Ser Thr Tyr Ile 360 365 370 gag ttc tac atc taataggtat ttacgacaaa tag 1254 Glu Phe Tyr Ile 375 <210> 188 <211> 377 <212> PRT <213> Corynebacterium glutamicum <400> 188 Met Pro Thr Leu Ala Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly 1 5 10 15 Asp Val Ser Thr Glu Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala 20 25 30 Tyr His Arg Trp Gly Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn 35 40 45 Val Val Leu Ile Glu His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp 50 55 60 Trp Trp Ala Asp Leu Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile 65 70 75 80 Tyr Cys Val Ile Cys Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr 85 90 95 Gly Pro Gly Ser Met His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe 100 105 110 Pro Ala Thr Ser Ile Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu 115 120 125 Asp Ala Leu Gly Ile Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met 130 135 140 Gly Gly Ala Arg Thr Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val 145 150 155 160 Gly Ala Ala Ala Val Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln 165 170 175 Ile Gly Ile Gln Ser Ala Gln Ile Lys Ala Ile Glu Asn Asp His His 180 185 190 Trp His Glu Gly Asn Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly 195 200 205 Leu Gly Ala Ala Arg Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu 210 215 220 Glu Ile Asp Glu Arg Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro 225 230 235 240 Leu Gly Pro Tyr Arg Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr 245 250 255 Leu Asp Tyr Gln Ala Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser 260 265 270 Tyr Val Leu Leu Thr Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp 275 280 285 Arg Gly Gly Leu Asn Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu 290 295 300 Val Ala Gly Val Asp Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu 305 310 315 320 His Leu Ser Arg Asn Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val 325 330 335 Ser Pro Val Gly His Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp 340 345 350 Arg Ile Val Arg Asn Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn 355 360 365 Pro Ser Thr Tyr Ile Glu Phe Tyr Ile 370 375 <210> 189 <211> 1210 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1210) <223> FRXA00403 <400> 189 tttttcagac tcgtgagaat gcaaactaga ctagacagag ctgtccatat acactggacg 60 aagttttagt cttgtccacc cagaacaggc ggttattttc atg ccc acc ctc gcg 115 Met Pro Thr Leu Ala 1 5 cct tca ggt caa ctt gaa atc caa gcg atc ggt gat gtc tcc acc gaa 163 Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly Asp Val Ser Thr Glu 10 15 20 gcc gga gca atc att aca aac gct gaa atc gcc tat cac cgc tgg ggt 211 Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala Tyr His Arg Trp Gly 25 30 35 gaa tac cgc gta gat aaa gaa gga cgc agc aat gtc gtt ctc atc gaa 259 Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn Val Val Leu Ile Glu 40 45 50 cac gcc ctc act gga gat tcc aac gca gcc gat tgg tgg gct gac ttg 307 His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp Trp Trp Ala Asp Leu 55 60 65 ctc ggt ccc ggc aaa gcc atc aac act gat att tac tgc gtg atc tgt 355 Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile Tyr Cys Val Ile Cys 70 75 80 85 acc aac gtc atc ggt ggt tgc aac ggt tcc acc gga cct ggc tcc atg 403 Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr Gly Pro Gly Ser Met 90 95 100 cat cca gat gga aat ttc tgg ggt aat cgc ttc ccc gcc acg tcc att 451 His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe Pro Ala Thr Ser Ile 105 110 115 cgt gat cag gta aac gcc gaa aaa caa ttc ctc gac gca ctc ggc atc 499 Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu Asp Ala Leu Gly Ile 120 125 130 acc acg gtc gcc gca gta ctt ggt ggt tcc atg ggt ggt gcc cgc acc 547 Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met Gly Gly Ala Arg Thr 135 140 145 cta gag tgg gcc gca atg tac cca gaa act gtt ggc gca gct gct gtt 595 Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val Gly Ala Ala Ala Val 150 155 160 165 ctt gca gtt tct gca cgc gcc agc gcc tgg caa atc ggc att caa tcc 643 Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln Ile Gly Ile Gln Ser 170 175 180 gcc caa att aag gcg att gaa aac gac cac cac tgg cac gaa ggc aac 691 Ala Gln Ile Lys Ala Ile Glu Asn Asp His His Trp His Glu Gly Asn 185 190 195 tac tac gaa tcc ggc tgc aac cca gcc acc gga ctc ggc gcc gcc cga 739 Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly Leu Gly Ala Ala Arg 200 205 210 cgc atc gcc cac ctc acc tac cgt ggc gaa cta gaa atc gac gaa cgc 787 Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu Glu Ile Asp Glu Arg 215 220 225 ttc ggc acc aaa gcc caa aag aac gaa aac cca ctc ggt ccc tac cgc 835 Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro Leu Gly Pro Tyr Arg 230 235 240 245 aag ccc gac cag cgc ttc gcc gtg gaa tcc tac ttg gac tac caa gca 883 Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr Leu Asp Tyr Gln Ala 250 255 260 gac aag cta gta cag cgt ttc gac gcc ggc tcc tac gtc ttg ctc acc 931 Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser Tyr Val Leu Leu Thr 265 270 275 gac gcc ctc aac cgc cac gac att ggt cgc gac cgc gga ggc ctc aac 979 Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp Arg Gly Gly Leu Asn 280 285 290 aag gca ctc gaa tcc atc aaa gtt cca gtc ctt gtc gca ggc gta gat 1027 Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu Val Ala Gly Val Asp 295 300 305 acc gat att ttg tac ccc tac cac cag caa gaa cac ctc tcc aga aac 1075 Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu His Leu Ser Arg Asn 310 315 320 325 ctg gga aat cta ctg gca atg gca aaa atc gta tcc cct gtc ggc cac 1123 Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val Ser Pro Val Gly His 330 335 340 gat gct ttc ctc acc gaa agc cgc caa atg gat cgc atc gtg agg aac 1171 Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp Arg Ile Val Arg Asn 345 350 355 ttc ttc agc ctc atc tcc cca gac gaa gac aac cct tcg 1210 Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn Pro Ser 360 365 370 <210> 190 <211> 370 <212> PRT <213> Corynebacterium glutamicum <400> 190 Met Pro Thr Leu Ala Pro Ser Gly Gln Leu Glu Ile Gln Ala Ile Gly 1 5 10 15 Asp Val Ser Thr Glu Ala Gly Ala Ile Ile Thr Asn Ala Glu Ile Ala 20 25 30 Tyr His Arg Trp Gly Glu Tyr Arg Val Asp Lys Glu Gly Arg Ser Asn 35 40 45 Val Val Leu Ile Glu His Ala Leu Thr Gly Asp Ser Asn Ala Ala Asp 50 55 60 Trp Trp Ala Asp Leu Leu Gly Pro Gly Lys Ala Ile Asn Thr Asp Ile 65 70 75 80 Tyr Cys Val Ile Cys Thr Asn Val Ile Gly Gly Cys Asn Gly Ser Thr 85 90 95 Gly Pro Gly Ser Met His Pro Asp Gly Asn Phe Trp Gly Asn Arg Phe 100 105 110 Pro Ala Thr Ser Ile Arg Asp Gln Val Asn Ala Glu Lys Gln Phe Leu 115 120 125 Asp Ala Leu Gly Ile Thr Thr Val Ala Ala Val Leu Gly Gly Ser Met 130 135 140 Gly Gly Ala Arg Thr Leu Glu Trp Ala Ala Met Tyr Pro Glu Thr Val 145 150 155 160 Gly Ala Ala Ala Val Leu Ala Val Ser Ala Arg Ala Ser Ala Trp Gln 165 170 175 Ile Gly Ile Gln Ser Ala Gln Ile Lys Ala Ile Glu Asn Asp His His 180 185 190 Trp His Glu Gly Asn Tyr Tyr Glu Ser Gly Cys Asn Pro Ala Thr Gly 195 200 205 Leu Gly Ala Ala Arg Arg Ile Ala His Leu Thr Tyr Arg Gly Glu Leu 210 215 220 Glu Ile Asp Glu Arg Phe Gly Thr Lys Ala Gln Lys Asn Glu Asn Pro 225 230 235 240 Leu Gly Pro Tyr Arg Lys Pro Asp Gln Arg Phe Ala Val Glu Ser Tyr 245 250 255 Leu Asp Tyr Gln Ala Asp Lys Leu Val Gln Arg Phe Asp Ala Gly Ser 260 265 270 Tyr Val Leu Leu Thr Asp Ala Leu Asn Arg His Asp Ile Gly Arg Asp 275 280 285 Arg Gly Gly Leu Asn Lys Ala Leu Glu Ser Ile Lys Val Pro Val Leu 290 295 300 Val Ala Gly Val Asp Thr Asp Ile Leu Tyr Pro Tyr His Gln Gln Glu 305 310 315 320 His Leu Ser Arg Asn Leu Gly Asn Leu Leu Ala Met Ala Lys Ile Val 325 330 335 Ser Pro Val Gly His Asp Ala Phe Leu Thr Glu Ser Arg Gln Met Asp 340 345 350 Arg Ile Val Arg Asn Phe Phe Ser Leu Ile Ser Pro Asp Glu Asp Asn 355 360 365 Pro Ser 370 <210> 191 <211> 687 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(664) <223> RXS03158 <400> 191 caaagctcac cgaaggcacc aacgccaagt tggttgttga caacaccttg gcatccccat 60 acctgcagca gccactaaaa ctcggcgcac acgcaagtcc ttg cac tcc acc acc 115 Leu His Ser Thr Thr 1 5 aag tac atc gaa gga cac tcc gac gtt gtt ggc ggc ctt gtg ggt acc 163 Lys Tyr Ile Glu Gly His Ser Asp Val Val Gly Gly Leu Val Gly Thr 10 15 20 aac gac cag gaa atg gac gaa gaa ctg ctg ttc atg cag ggc ggc atc 211 Asn Asp Gln Glu Met Asp Glu Glu Leu Leu Phe Met Gln Gly Gly Ile 25 30 35 gga ccg atc cca tca gtt ttc gat gca tac ctg acc gcc cgt ggc ctc 259 Gly Pro Ile Pro Ser Val Phe Asp Ala Tyr Leu Thr Ala Arg Gly Leu 40 45 50 aag acc ctt gca gtg cgc atg gat cgc cac tgc gac aac gca gaa aag 307 Lys Thr Leu Ala Val Arg Met Asp Arg His Cys Asp Asn Ala Glu Lys 55 60 65 atc gcg gaa ttc ctg gac tcc cgc cca gag gtc tcc acc gtg ctc tac 355 Ile Ala Glu Phe Leu Asp Ser Arg Pro Glu Val Ser Thr Val Leu Tyr 70 75 80 85 cca ggt ctg aag aac cac cca ggc cac gaa gtc gca gcg aag cag atg 403 Pro Gly Leu Lys Asn His Pro Gly His Glu Val Ala Ala Lys Gln Met 90 95 100 aag cgc ttc ggc ggc atg atc tcc gtc cgt ttc gca ggc ggc gaa gaa 451 Lys Arg Phe Gly Gly Met Ile Ser Val Arg Phe Ala Gly Gly Glu Glu 105 110 115 gca gct aag aag ttc tgt acc tcc acc aaa ctg atc tgt ctg gcc gag 499 Ala Ala Lys Lys Phe Cys Thr Ser Thr Lys Leu Ile Cys Leu Ala Glu 120 125 130 tcc ctc ggt ggc gtg gaa tcc ctc ctg gag cac cca gca acc atg acc 547 Ser Leu Gly Gly Val Glu Ser Leu Leu Glu His Pro Ala Thr Met Thr 135 140 145 cac cag tca gct gcc ggc tct cag ctc gag gtt ccc cgc gac ctc gtg 595 His Gln Ser Ala Ala Gly Ser Gln Leu Glu Val Pro Arg Asp Leu Val 150 155 160 165 cgc atc tcc att ggt att gaa gac att gaa gac ctg ctc gca gat gtc 643 Arg Ile Ser Ile Gly Ile Glu Asp Ile Glu Asp Leu Leu Ala Asp Val 170 175 180 gag cag gcc ctc aat aac ctt tagaaactat ttggcggcaa gca 687 Glu Gln Ala Leu Asn Asn Leu 185 <210> 192 <211> 188 <212> PRT <213> Corynebacterium glutamicum <400> 192 Leu His Ser Thr Thr Lys Tyr Ile Glu Gly His Ser Asp Val Val Gly 1 5 10 15 Gly Leu Val Gly Thr Asn Asp Gln Glu Met Asp Glu Glu Leu Leu Phe 20 25 30 Met Gln Gly Gly Ile Gly Pro Ile Pro Ser Val Phe Asp Ala Tyr Leu 35 40 45 Thr Ala Arg Gly Leu Lys Thr Leu Ala Val Arg Met Asp Arg His Cys 50 55 60 Asp Asn Ala Glu Lys Ile Ala Glu Phe Leu Asp Ser Arg Pro Glu Val 65 70 75 80 Ser Thr Val Leu Tyr Pro Gly Leu Lys Asn His Pro Gly His Glu Val 85 90 95 Ala Ala Lys Gln Met Lys Arg Phe Gly Gly Met Ile Ser Val Arg Phe 100 105 110 Ala Gly Gly Glu Glu Ala Ala Lys Lys Phe Cys Thr Ser Thr Lys Leu 115 120 125 Ile Cys Leu Ala Glu Ser Leu Gly Gly Val Glu Ser Leu Leu Glu His 130 135 140 Pro Ala Thr Met Thr His Gln Ser Ala Ala Gly Ser Gln Leu Glu Val 145 150 155 160 Pro Arg Asp Leu Val Arg Ile Ser Ile Gly Ile Glu Asp Ile Glu Asp 165 170 175 Leu Leu Ala Asp Val Glu Gln Ala Leu Asn Asn Leu 180 185 <210> 193 <211> 617 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(594) <223> FRXA00254 <400> 193 cag cca cta aaa ctc ggc gca cac gca gtc ttg cac tcc acc acc aag 48 Gln Pro Leu Lys Leu Gly Ala His Ala Val Leu His Ser Thr Thr Lys 1 5 10 15 tac atc gga gga cac tcc gac gtt gtt ggc ggc ctt gtg gtt acc aac 96 Tyr Ile Gly Gly His Ser Asp Val Val Gly Gly Leu Val Val Thr Asn 20 25 30 gac cag gaa atg gac gaa gaa ctg ctg ttc atg cag ggc ggc atc gga 144 Asp Gln Glu Met Asp Glu Glu Leu Leu Phe Met Gln Gly Gly Ile Gly 35 40 45 ccg atc cca tca gtt ttc gat gca tac ctg acc gcc cgt ggc ctc aag 192 Pro Ile Pro Ser Val Phe Asp Ala Tyr Leu Thr Ala Arg Gly Leu Lys 50 55 60 acc ctt gca gtg cgc atg gat cgc cac tgc gac aac gca gaa aag atc 240 Thr Leu Ala Val Arg Met Asp Arg His Cys Asp Asn Ala Glu Lys Ile 65 70 75 80 gcg gaa ttc ctg gac tcc cgc cca gag gtc tcc acc gtg ctc tac cca 288 Ala Glu Phe Leu Asp Ser Arg Pro Glu Val Ser Thr Val Leu Tyr Pro 85 90 95 ggt ctg aag aac cac cca ggc cac gaa gtc gca gcg aag cag atg aag 336 Gly Leu Lys Asn His Pro Gly His Glu Val Ala Ala Lys Gln Met Lys 100 105 110 cgc ttc ggc ggc atg atc tcc gtc cgt ttc gca ggc ggc gaa gaa gca 384 Arg Phe Gly Gly Met Ile Ser Val Arg Phe Ala Gly Gly Glu Glu Ala 115 120 125 gct aag aag ttc tgt acc tcc acc aaa ctg atc tgt ctg gcc gag tcc 432 Ala Lys Lys Phe Cys Thr Ser Thr Lys Leu Ile Cys Leu Ala Glu Ser 130 135 140 ctc ggt ggc gtg gaa tcc ctc ctg gag cac cca gca acc atg acc cac 480 Leu Gly Gly Val Glu Ser Leu Leu Glu His Pro Ala Thr Met Thr His 145 150 155 160 cag tca gct gcc ggc tct cag ctc gag gtt ccc cgc gac ctc gtg cgc 528 Gln Ser Ala Ala Gly Ser Gln Leu Glu Val Pro Arg Asp Leu Val Arg 165 170 175 atc tcc att ggt att gaa gac att gaa gac ctg ctc gca gat gtc gag 576 Ile Ser Ile Gly Ile Glu Asp Ile Glu Asp Leu Leu Ala Asp Val Glu 180 185 190 cag gcc ctc aat aac ctt tagaaactat ttggcggcaa gca 617 Gln Ala Leu Asn Asn Leu 195 <210> 194 <211> 198 <212> PRT <213> Corynebacterium glutamicum <400> 194 Gln Pro Leu Lys Leu Gly Ala His Ala Val Leu His Ser Thr Thr Lys 1 5 10 15 Tyr Ile Gly Gly His Ser Asp Val Val Gly Gly Leu Val Val Thr Asn 20 25 30 Asp Gln Glu Met Asp Glu Glu Leu Leu Phe Met Gln Gly Gly Ile Gly 35 40 45 Pro Ile Pro Ser Val Phe Asp Ala Tyr Leu Thr Ala Arg Gly Leu Lys 50 55 60 Thr Leu Ala Val Arg Met Asp Arg His Cys Asp Asn Ala Glu Lys Ile 65 70 75 80 Ala Glu Phe Leu Asp Ser Arg Pro Glu Val Ser Thr Val Leu Tyr Pro 85 90 95 Gly Leu Lys Asn His Pro Gly His Glu Val Ala Ala Lys Gln Met Lys 100 105 110 Arg Phe Gly Gly Met Ile Ser Val Arg Phe Ala Gly Gly Glu Glu Ala 115 120 125 Ala Lys Lys Phe Cys Thr Ser Thr Lys Leu Ile Cys Leu Ala Glu Ser 130 135 140 Leu Gly Gly Val Glu Ser Leu Leu Glu His Pro Ala Thr Met Thr His 145 150 155 160 Gln Ser Ala Ala Gly Ser Gln Leu Glu Val Pro Arg Asp Leu Val Arg 165 170 175 Ile Ser Ile Gly Ile Glu Asp Ile Glu Asp Leu Leu Ala Asp Val Glu 180 185 190 Gln Ala Leu Asn Asn Leu 195 <210> 195 <211> 1170 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1147) <223> RXA02532 <400> 195 gatgaatttt tacccaccat ctgtacctat taaccctgcg tggcgtccac ccacagtaac 60 tgtgcaagcg ggacggccag ccagaactcc tggtgcgccg atg aac cca cct atc 115 Met Asn Pro Pro Ile 1 5 acg ttg tcc agc act tat gtt cat gat tca gaa aaa gct tat ggg cgc 163 Thr Leu Ser Ser Thr Tyr Val His Asp Ser Glu Lys Ala Tyr Gly Arg 10 15 20 gat ggc aat gat gga tgg ggt gca ttt gag gct gcc atg gga act cta 211 Asp Gly Asn Asp Gly Trp Gly Ala Phe Glu Ala Ala Met Gly Thr Leu 25 30 35 gat ggt ggg ttc gcg gta tct tat tct tca ggt ttg gca gcg gca acg 259 Asp Gly Gly Phe Ala Val Ser Tyr Ser Ser Gly Leu Ala Ala Ala Thr 40 45 50 tcg att gct gat ttg gtt cct act ggt ggc aca gtt gtt tta cct aaa 307 Ser Ile Ala Asp Leu Val Pro Thr Gly Gly Thr Val Val Leu Pro Lys 55 60 65 gct gcc tat tat ggc gtg acc aat att ttc gcc agg atg gaa gcc cgc 355 Ala Ala Tyr Tyr Gly Val Thr Asn Ile Phe Ala Arg Met Glu Ala Arg 70 75 80 85 gga agg ctg aag gtt cga act gtt gat gca gac aat acc gaa gaa gtg 403 Gly Arg Leu Lys Val Arg Thr Val Asp Ala Asp Asn Thr Glu Glu Val 90 95 100 att gct gct gct caa ggt gca gat gtg gtg tgg gtg gaa tcg atc gct 451 Ile Ala Ala Ala Gln Gly Ala Asp Val Val Trp Val Glu Ser Ile Ala 105 110 115 aat ccg acg atg gtg gta gct gat atc cct gca ata gtc gac ggt gtg 499 Asn Pro Thr Met Val Val Ala Asp Ile Pro Ala Ile Val Asp Gly Val 120 125 130 cgt ggg ctt gga gtt ttg act gtc gtt gac gcg act ttc gca acg cca 547 Arg Gly Leu Gly Val Leu Thr Val Val Asp Ala Thr Phe Ala Thr Pro 135 140 145 ctt cgt caa cgt cca ttg gaa ctt ggt gct gat att gtg ctt tac tcg 595 Leu Arg Gln Arg Pro Leu Glu Leu Gly Ala Asp Ile Val Leu Tyr Ser 150 155 160 165 gca acc aaa ctt atc ggt gga cac tct gat ctt ctt ctt gga gtc gca 643 Ala Thr Lys Leu Ile Gly Gly His Ser Asp Leu Leu Leu Gly Val Ala 170 175 180 gtg tgc aag tct gag cac cat gcg cag ttt ctt gcc act cac cgt cat 691 Val Cys Lys Ser Glu His His Ala Gln Phe Leu Ala Thr His Arg His 185 190 195 gat cat ggt tca gtg ccg gga ggt ctt gaa gcg ttt ctt gct ctc cgt 739 Asp His Gly Ser Val Pro Gly Gly Leu Glu Ala Phe Leu Ala Leu Arg 200 205 210 gga ttg tat tcc ttg gcg gtg cgt ctt gat cga gca gaa tcc aac gca 787 Gly Leu Tyr Ser Leu Ala Val Arg Leu Asp Arg Ala Glu Ser Asn Ala 215 220 225 gca gaa ctt tcg cgg cga ctt aac gcg cat cct tcg gtt acc cgc gtc 835 Ala Glu Leu Ser Arg Arg Leu Asn Ala His Pro Ser Val Thr Arg Val 230 235 240 245 aat tat cca gga ctt cct gat gat ccc caa cat gaa aaa gcc gtg cga 883 Asn Tyr Pro Gly Leu Pro Asp Asp Pro Gln His Glu Lys Ala Val Arg 250 255 260 gtc cta ccc tct gga tgt gga aac atg ttg tca ttt gag ctt gat gca 931 Val Leu Pro Ser Gly Cys Gly Asn Met Leu Ser Phe Glu Leu Asp Ala 265 270 275 aca cct gaa cga act gat gag att ctc gaa agc ctg tca ctt tta acc 979 Thr Pro Glu Arg Thr Asp Glu Ile Leu Glu Ser Leu Ser Leu Leu Thr 280 285 290 cac gcg acc agt tgg gga ggt gtg gaa aca gcc att gaa cgt cgc acc 1027 His Ala Thr Ser Trp Gly Gly Val Glu Thr Ala Ile Glu Arg Arg Thr 295 300 305 agg cgg gat gct gaa gtg gtg gca gaa gta ccg atg act ctt tgc cgc 1075 Arg Arg Asp Ala Glu Val Val Ala Glu Val Pro Met Thr Leu Cys Arg 310 315 320 325 gtt tcc gta gga att gaa gac gtt gaa gat cta tgg gaa gac ctc aac 1123 Val Ser Val Gly Ile Glu Asp Val Glu Asp Leu Trp Glu Asp Leu Asn 330 335 340 gcc tca atc gac aaa gtt ctg ggt tagaactcgt agccagtaac cag 1170 Ala Ser Ile Asp Lys Val Leu Gly 345 <210> 196 <211> 349 <212> PRT <213> Corynebacterium glutamicum <400> 196 Met Asn Pro Pro Ile Thr Leu Ser Ser Thr Tyr Val His Asp Ser Glu 1 5 10 15 Lys Ala Tyr Gly Arg Asp Gly Asn Asp Gly Trp Gly Ala Phe Glu Ala 20 25 30 Ala Met Gly Thr Leu Asp Gly Gly Phe Ala Val Ser Tyr Ser Ser Gly 35 40 45 Leu Ala Ala Ala Thr Ser Ile Ala Asp Leu Val Pro Thr Gly Gly Thr 50 55 60 Val Val Leu Pro Lys Ala Ala Tyr Tyr Gly Val Thr Asn Ile Phe Ala 65 70 75 80 Arg Met Glu Ala Arg Gly Arg Leu Lys Val Arg Thr Val Asp Ala Asp 85 90 95 Asn Thr Glu Glu Val Ile Ala Ala Ala Gln Gly Ala Asp Val Val Trp 100 105 110 Val Glu Ser Ile Ala Asn Pro Thr Met Val Val Ala Asp Ile Pro Ala 115 120 125 Ile Val Asp Gly Val Arg Gly Leu Gly Val Leu Thr Val Val Asp Ala 130 135 140 Thr Phe Ala Thr Pro Leu Arg Gln Arg Pro Leu Glu Leu Gly Ala Asp 145 150 155 160 Ile Val Leu Tyr Ser Ala Thr Lys Leu Ile Gly Gly His Ser Asp Leu 165 170 175 Leu Leu Gly Val Ala Val Cys Lys Ser Glu His His Ala Gln Phe Leu 180 185 190 Ala Thr His Arg His Asp His Gly Ser Val Pro Gly Gly Leu Glu Ala 195 200 205 Phe Leu Ala Leu Arg Gly Leu Tyr Ser Leu Ala Val Arg Leu Asp Arg 210 215 220 Ala Glu Ser Asn Ala Ala Glu Leu Ser Arg Arg Leu Asn Ala His Pro 225 230 235 240 Ser Val Thr Arg Val Asn Tyr Pro Gly Leu Pro Asp Asp Pro Gln His 245 250 255 Glu Lys Ala Val Arg Val Leu Pro Ser Gly Cys Gly Asn Met Leu Ser 260 265 270 Phe Glu Leu Asp Ala Thr Pro Glu Arg Thr Asp Glu Ile Leu Glu Ser 275 280 285 Leu Ser Leu Leu Thr His Ala Thr Ser Trp Gly Gly Val Glu Thr Ala 290 295 300 Ile Glu Arg Arg Thr Arg Arg Asp Ala Glu Val Val Ala Glu Val Pro 305 310 315 320 Met Thr Leu Cys Arg Val Ser Val Gly Ile Glu Asp Val Glu Asp Leu 325 330 335 Trp Glu Asp Leu Asn Ala Ser Ile Asp Lys Val Leu Gly 340 345 <210> 197 <211> 861 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(838) <223> RXS03159 <400> 197 aggggctagt tttacacaaa agtggacagc ttggtctatc attgccagaa gaccggtcct 60 tttagggcca tagaattctg attacaggag ttgatctacc ttg tct ttt gac cca 115 Leu Ser Phe Asp Pro 1 5 aac acc cag ggt ttc tcc act gca tcg att cac gct ggg tat gag cca 163 Asn Thr Gln Gly Phe Ser Thr Ala Ser Ile His Ala Gly Tyr Glu Pro 10 15 20 gac gac tac tac ggt tcg att aac acc cca atc tat gcc tcc acc acc 211 Asp Asp Tyr Tyr Gly Ser Ile Asn Thr Pro Ile Tyr Ala Ser Thr Thr 25 30 35 ttc gcg cag aac gct cca aac gaa ctg cgc aaa ggc tac gag tac acc 259 Phe Ala Gln Asn Ala Pro Asn Glu Leu Arg Lys Gly Tyr Glu Tyr Thr 40 45 50 cgt gtg ggc aac ccc acc atc gtg gca tta gag cag acc gtc gca gca 307 Arg Val Gly Asn Pro Thr Ile Val Ala Leu Glu Gln Thr Val Ala Ala 55 60 65 ctc gaa ggc gca aag tat ggc cgc gca ttc tcc tcc ggc atg gct gca 355 Leu Glu Gly Ala Lys Tyr Gly Arg Ala Phe Ser Ser Gly Met Ala Ala 70 75 80 85 acc gac atc ctg ttc cgc atc atc ctc aag ccg ggc gat cac atc gtc 403 Thr Asp Ile Leu Phe Arg Ile Ile Leu Lys Pro Gly Asp His Ile Val 90 95 100 ctc ggc aac gat gct tac ggc gga acc tac cgc ctg atc gac acc gta 451 Leu Gly Asn Asp Ala Tyr Gly Gly Thr Tyr Arg Leu Ile Asp Thr Val 105 110 115 ttc acc gca tgg ggc gtc gaa tac acc gtt gtt gat acc tcc gtc gtg 499 Phe Thr Ala Trp Gly Val Glu Tyr Thr Val Val Asp Thr Ser Val Val 120 125 130 gaa gag gtc aag gca gcg atc aag gac aac acc aag ctg atc tgg gtg 547 Glu Glu Val Lys Ala Ala Ile Lys Asp Asn Thr Lys Leu Ile Trp Val 135 140 145 gaa acc cca acc aac cca gca ctt ggc atc acc gac atc gaa gca gta 595 Glu Thr Pro Thr Asn Pro Ala Leu Gly Ile Thr Asp Ile Glu Ala Val 150 155 160 165 gca aag ctc acc gaa ggc acc aac gcc aag ttg gtt gtt gac aac acc 643 Ala Lys Leu Thr Glu Gly Thr Asn Ala Lys Leu Val Val Asp Asn Thr 170 175 180 ttg gca tcc cca tac ctg cag cag cca cta aaa ctc ggc gca cac gca 691 Leu Ala Ser Pro Tyr Leu Gln Gln Pro Leu Lys Leu Gly Ala His Ala 185 190 195 agt cct tgc act cca cca cca agt aca tcg aag gac act ccg acg ttg 739 Ser Pro Cys Thr Pro Pro Pro Ser Thr Ser Lys Asp Thr Pro Thr Leu 200 205 210 ttg gcg gcc ttg tgg gta cca acg acc agg aaa tgg acg aag aac tgc 787 Leu Ala Ala Leu Trp Val Pro Thr Thr Arg Lys Trp Thr Lys Asn Cys 215 220 225 tgt tca tgc agg gcg gca tcg gac cga tcc cat cag ttt tcg atg cat 835 Cys Ser Cys Arg Ala Ala Ser Asp Arg Ser His Gln Phe Ser Met His 230 235 240 245 acc tgaccgcccg tggcctcaag acc 861 Thr <210> 198 <211> 246 <212> PRT <213> Corynebacterium glutamicum <400> 198 Leu Ser Phe Asp Pro Asn Thr Gln Gly Phe Ser Thr Ala Ser Ile His 1 5 10 15 Ala Gly Tyr Glu Pro Asp Asp Tyr Tyr Gly Ser Ile Asn Thr Pro Ile 20 25 30 Tyr Ala Ser Thr Thr Phe Ala Gln Asn Ala Pro Asn Glu Leu Arg Lys 35 40 45 Gly Tyr Glu Tyr Thr Arg Val Gly Asn Pro Thr Ile Val Ala Leu Glu 50 55 60 Gln Thr Val Ala Ala Leu Glu Gly Ala Lys Tyr Gly Arg Ala Phe Ser 65 70 75 80 Ser Gly Met Ala Ala Thr Asp Ile Leu Phe Arg Ile Ile Leu Lys Pro 85 90 95 Gly Asp His Ile Val Leu Gly Asn Asp Ala Tyr Gly Gly Thr Tyr Arg 100 105 110 Leu Ile Asp Thr Val Phe Thr Ala Trp Gly Val Glu Tyr Thr Val Val 115 120 125 Asp Thr Ser Val Val Glu Glu Val Lys Ala Ala Ile Lys Asp Asn Thr 130 135 140 Lys Leu Ile Trp Val Glu Thr Pro Thr Asn Pro Ala Leu Gly Ile Thr 145 150 155 160 Asp Ile Glu Ala Val Ala Lys Leu Thr Glu Gly Thr Asn Ala Lys Leu 165 170 175 Val Val Asp Asn Thr Leu Ala Ser Pro Tyr Leu Gln Gln Pro Leu Lys 180 185 190 Leu Gly Ala His Ala Ser Pro Cys Thr Pro Pro Pro Ser Thr Ser Lys 195 200 205 Asp Thr Pro Thr Leu Leu Ala Ala Leu Trp Val Pro Thr Thr Arg Lys 210 215 220 Trp Thr Lys Asn Cys Cys Ser Cys Arg Ala Ala Ser Asp Arg Ser His 225 230 235 240 Gln Phe Ser Met His Thr 245 <210> 199 <211> 703 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(703) <223> FRXA02768 <220> <221> misc_feature <222> 676, 687, 690, 691, 693 <223> n = a, c, g, or t <220> <221> VARIANT <222> 192 <223> Xaa = His or Gln <220> <221> VARIANT <222> 196 <223> Xaa = Ile, Thr, Asn, or Ser <220> <221> VARIANT <222> 197 <223> Xaa = Phe, Leu, Ser, Tyr, Cys, <223> Trp, or STOP CODON <220> <221> VARIANT <222> 198 <223> Xaa = Val, Ala, Glu, or Gly <400> 199 aggggctagt tttacacaaa agtggacagc ttggtctatc attgccagaa gaccggtcct 60 tttagggcca tagaattctg attacaggag ttgatctacc ttg tct ttt gac cca 115 Leu Ser Phe Asp Pro 1 5 aac acc cag ggt ttc tcc act gca tcg att cac gct ggg tat gag cca 163 Asn Thr Gln Gly Phe Ser Thr Ala Ser Ile His Ala Gly Tyr Glu Pro 10 15 20 gac gac tac tac ggt tcg att aac acc cca atc tat gcc tcc acc acc 211 Asp Asp Tyr Tyr Gly Ser Ile Asn Thr Pro Ile Tyr Ala Ser Thr Thr 25 30 35 ttc gcg cag aac gct cca aac gaa ctg cgc aaa ggc tac gag tac acc 259 Phe Ala Gln Asn Ala Pro Asn Glu Leu Arg Lys Gly Tyr Glu Tyr Thr 40 45 50 cgt gtg ggc aac ccc acc atc gtg gca tta gag cag acc gtc gca gca 307 Arg Val Gly Asn Pro Thr Ile Val Ala Leu Glu Gln Thr Val Ala Ala 55 60 65 ctc gaa ggc gca aag tat ggc cgc gca ttc tcc tcc ggc atg gct gca 355 Leu Glu Gly Ala Lys Tyr Gly Arg Ala Phe Ser Ser Gly Met Ala Ala 70 75 80 85 acc gac atc ctg ttc cgc atc atc ctc aag ccg ggc gat cac atc gtc 403 Thr Asp Ile Leu Phe Arg Ile Ile Leu Lys Pro Gly Asp His Ile Val 90 95 100 ctc ggc aac gat gct tac ggc gga acc tac cgc ctg atc gac acc gta 451 Leu Gly Asn Asp Ala Tyr Gly Gly Thr Tyr Arg Leu Ile Asp Thr Val 105 110 115 ttc acc gca tgg ggc gtc gaa tac acc gtt gtt gat acc tcc gtc gtg 499 Phe Thr Ala Trp Gly Val Glu Tyr Thr Val Val Asp Thr Ser Val Val 120 125 130 gaa gag gtc aag gca gcg atc aag gac aac acc aag gct gat ctt ggt 547 Glu Glu Val Lys Ala Ala Ile Lys Asp Asn Thr Lys Ala Asp Leu Gly 135 140 145 gga aac ccc aac caa ccc agc act ttg gca tta ccc gac atc gaa gca 595 Gly Asn Pro Asn Gln Pro Ser Thr Leu Ala Leu Pro Asp Ile Glu Ala 150 155 160 165 gtn tgc aaa act tca ccc gaa agg cac caa ccc caa gct tgt tgt ttg 643 Val Cys Lys Thr Ser Pro Glu Arg His Gln Pro Gln Ala Cys Cys Leu 170 175 180 aca aca cct tcg cat tcc cca tac ctg cag can cca ctt aaa ant tnn 691 Thr Thr Pro Ser His Ser Pro Tyr Leu Gln Xaa Pro Leu Lys Xaa Xaa 185 190 195 gng cac acg cag 703 Xaa His Thr Gln 200 <210> 200 <211> 201 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 192 <223> Xaa = His or Gln <220> <221> VARIANT <222> 196 <223> Xaa = Ile, Thr, Asn, or Ser <220> <221> VARIANT <222> 197 <223> Xaa = Phe, Leu, Ser, Tyr, Cys, <223> Trp, or STOP CODON <220> <221> VARIANT <222> 198 <223> Xaa = Val, Ala, Glu, or Gly <400> 200 Leu Ser Phe Asp Pro Asn Thr Gln Gly Phe Ser Thr Ala Ser Ile His 1 5 10 15 Ala Gly Tyr Glu Pro Asp Asp Tyr Tyr Gly Ser Ile Asn Thr Pro Ile 20 25 30 Tyr Ala Ser Thr Thr Phe Ala Gln Asn Ala Pro Asn Glu Leu Arg Lys 35 40 45 Gly Tyr Glu Tyr Thr Arg Val Gly Asn Pro Thr Ile Val Ala Leu Glu 50 55 60 Gln Thr Val Ala Ala Leu Glu Gly Ala Lys Tyr Gly Arg Ala Phe Ser 65 70 75 80 Ser Gly Met Ala Ala Thr Asp Ile Leu Phe Arg Ile Ile Leu Lys Pro 85 90 95 Gly Asp His Ile Val Leu Gly Asn Asp Ala Tyr Gly Gly Thr Tyr Arg 100 105 110 Leu Ile Asp Thr Val Phe Thr Ala Trp Gly Val Glu Tyr Thr Val Val 115 120 125 Asp Thr Ser Val Val Glu Glu Val Lys Ala Ala Ile Lys Asp Asn Thr 130 135 140 Lys Ala Asp Leu Gly Gly Asn Pro Asn Gln Pro Ser Thr Leu Ala Leu 145 150 155 160 Pro Asp Ile Glu Ala Val Cys Lys Thr Ser Pro Glu Arg His Gln Pro 165 170 175 Gln Ala Cys Cys Leu Thr Thr Pro Ser His Ser Pro Tyr Leu Gln Xaa 180 185 190 Pro Leu Lys Xaa Xaa Xaa His Thr Gln 195 200 <210> 201 <211> 1113 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1090) <223> RXA00216 <400> 201 gtgttgctcg cggccaggca gcagtgctgt acctgcctga cgcggatggt gacatcgttc 60 ttggatcagg caccatctgc cacacggagt cttaagaaaa ttg ggc gct tat ggt 115 Leu Gly Ala Tyr Gly 1 5 tta ggt gag ctt cct gga aaa tcc gcc gcg gaa gcc gcc gac att att 163 Leu Gly Glu Leu Pro Gly Lys Ser Ala Ala Glu Ala Ala Asp Ile Ile 10 15 20 cag ggt gaa acg ggc gat ctt ctc cat att cct cag ctt ccg gcg cga 211 Gln Gly Glu Thr Gly Asp Leu Leu His Ile Pro Gln Leu Pro Ala Arg 25 30 35 ggt ttg ggt gct gat ctg atc ggt cga acc gtc ggt ctg ctg gac atg 259 Gly Leu Gly Ala Asp Leu Ile Gly Arg Thr Val Gly Leu Leu Asp Met 40 45 50 atc aac gtt gat cgc ggg gcc cga tct tgg gtg atg agc aca cgc ccc 307 Ile Asn Val Asp Arg Gly Ala Arg Ser Trp Val Met Ser Thr Arg Pro 55 60 65 agc aga ttg acg cac ctg acc ggc gat ttc ctt gac atg gat ttg gat 355 Ser Arg Leu Thr His Leu Thr Gly Asp Phe Leu Asp Met Asp Leu Asp 70 75 80 85 gcg tgc gag gaa acc tgg gga acg ggc gtc gac aag cta aaa atc caa 403 Ala Cys Glu Glu Thr Trp Gly Thr Gly Val Asp Lys Leu Lys Ile Gln 90 95 100 gtt gct ggt ccc tgg act tta ggt gcg cgc att gag ttg gcc aat ggc 451 Val Ala Gly Pro Trp Thr Leu Gly Ala Arg Ile Glu Leu Ala Asn Gly 105 110 115 cat cgc gtt ttg tct gat cgc ggt gcg atg cgt gat ctc acg cag gcg 499 His Arg Val Leu Ser Asp Arg Gly Ala Met Arg Asp Leu Thr Gln Ala 120 125 130 ctg atc gcc ggc atc gat gcg cat gca cgc aag gtt gct ggg cga ttt 547 Leu Ile Ala Gly Ile Asp Ala His Ala Arg Lys Val Ala Gly Arg Phe 135 140 145 cgc gcc gaa gtg cag gtg caa att gat gag ccg gag ctg aaa tcg ctt 595 Arg Ala Glu Val Gln Val Gln Ile Asp Glu Pro Glu Leu Lys Ser Leu 150 155 160 165 atc gac ggc tcc ctc cct ggc act tcc acc ttt gac att att cct gcg 643 Ile Asp Gly Ser Leu Pro Gly Thr Ser Thr Phe Asp Ile Ile Pro Ala 170 175 180 gtg aat gtc gct gat gcc agt gaa cgt ttg cag cag gtc ttt agc tcg 691 Val Asn Val Ala Asp Ala Ser Glu Arg Leu Gln Gln Val Phe Ser Ser 185 190 195 att gag ggg ccg aca tat ctc aac ctc acc ggc cag att cct act tgg 739 Ile Glu Gly Pro Thr Tyr Leu Asn Leu Thr Gly Gln Ile Pro Thr Trp 200 205 210 gat gtg gct cgg ggt gcg ggc gcc gat act gtg cag att tcc atg gat 787 Asp Val Ala Arg Gly Ala Gly Ala Asp Thr Val Gln Ile Ser Met Asp 215 220 225 caa gtc cgt gga aat gaa cat ttg gat ggt ttt ggt gaa acc atc acc 835 Gln Val Arg Gly Asn Glu His Leu Asp Gly Phe Gly Glu Thr Ile Thr 230 235 240 245 agt gga att cgt ctt ggt ttg ggc att acg aca gga aaa gat gtc gta 883 Ser Gly Ile Arg Leu Gly Leu Gly Ile Thr Thr Gly Lys Asp Val Val 250 255 260 gat gaa ctg ctc gag cga ccg cgg caa aag gcc gtt gag gta gca cgc 931 Asp Glu Leu Leu Glu Arg Pro Arg Gln Lys Ala Val Glu Val Ala Arg 265 270 275 ttt ttt gat cgt tta ggt gtg ggc cga aac tat ctc gtg gat gct gtt 979 Phe Phe Asp Arg Leu Gly Val Gly Arg Asn Tyr Leu Val Asp Ala Val 280 285 290 gat att cat ccg ggt gag gat ttg gtg cag ggg acc atc acc gag gcc 1027 Asp Ile His Pro Gly Glu Asp Leu Val Gln Gly Thr Ile Thr Glu Ala 295 300 305 gcg cag gct tat cgc atg gcc cgg gtg atg tcg gag atg ttg tcg aag 1075 Ala Gln Ala Tyr Arg Met Ala Arg Val Met Ser Glu Met Leu Ser Lys 310 315 320 325 gat tca tgc gac ctt taaggcttta ccggcgctgg gtg 1113 Asp Ser Cys Asp Leu 330 <210> 202 <211> 330 <212> PRT <213> Corynebacterium glutamicum <400> 202 Leu Gly Ala Tyr Gly Leu Gly Glu Leu Pro Gly Lys Ser Ala Ala Glu 1 5 10 15 Ala Ala Asp Ile Ile Gln Gly Glu Thr Gly Asp Leu Leu His Ile Pro 20 25 30 Gln Leu Pro Ala Arg Gly Leu Gly Ala Asp Leu Ile Gly Arg Thr Val 35 40 45 Gly Leu Leu Asp Met Ile Asn Val Asp Arg Gly Ala Arg Ser Trp Val 50 55 60 Met Ser Thr Arg Pro Ser Arg Leu Thr His Leu Thr Gly Asp Phe Leu 65 70 75 80 Asp Met Asp Leu Asp Ala Cys Glu Glu Thr Trp Gly Thr Gly Val Asp 85 90 95 Lys Leu Lys Ile Gln Val Ala Gly Pro Trp Thr Leu Gly Ala Arg Ile 100 105 110 Glu Leu Ala Asn Gly His Arg Val Leu Ser Asp Arg Gly Ala Met Arg 115 120 125 Asp Leu Thr Gln Ala Leu Ile Ala Gly Ile Asp Ala His Ala Arg Lys 130 135 140 Val Ala Gly Arg Phe Arg Ala Glu Val Gln Val Gln Ile Asp Glu Pro 145 150 155 160 Glu Leu Lys Ser Leu Ile Asp Gly Ser Leu Pro Gly Thr Ser Thr Phe 165 170 175 Asp Ile Ile Pro Ala Val Asn Val Ala Asp Ala Ser Glu Arg Leu Gln 180 185 190 Gln Val Phe Ser Ser Ile Glu Gly Pro Thr Tyr Leu Asn Leu Thr Gly 195 200 205 Gln Ile Pro Thr Trp Asp Val Ala Arg Gly Ala Gly Ala Asp Thr Val 210 215 220 Gln Ile Ser Met Asp Gln Val Arg Gly Asn Glu His Leu Asp Gly Phe 225 230 235 240 Gly Glu Thr Ile Thr Ser Gly Ile Arg Leu Gly Leu Gly Ile Thr Thr 245 250 255 Gly Lys Asp Val Val Asp Glu Leu Leu Glu Arg Pro Arg Gln Lys Ala 260 265 270 Val Glu Val Ala Arg Phe Phe Asp Arg Leu Gly Val Gly Arg Asn Tyr 275 280 285 Leu Val Asp Ala Val Asp Ile His Pro Gly Glu Asp Leu Val Gln Gly 290 295 300 Thr Ile Thr Glu Ala Ala Gln Ala Tyr Arg Met Ala Arg Val Met Ser 305 310 315 320 Glu Met Leu Ser Lys Asp Ser Cys Asp Leu 325 330 <210> 203 <211> 623 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(600) <223> RXN00402 <400> 203 act gac gaa aag gat gga aag cca gta ttg ccc tac ttc gtc act cca 48 Thr Asp Glu Lys Asp Gly Lys Pro Val Leu Pro Tyr Phe Val Thr Pro 1 5 10 15 gat gct gct tac cac gga ttg aag tac gca gac ctt ggt gca cca gcc 96 Asp Ala Ala Tyr His Gly Leu Lys Tyr Ala Asp Leu Gly Ala Pro Ala 20 25 30 ttc ggc ctc aag gtt cgc gtt ggc ctt cta cgc gac acc ggc tcc acc 144 Phe Gly Leu Lys Val Arg Val Gly Leu Leu Arg Asp Thr Gly Ser Thr 35 40 45 ctc tcc gca ttc aac gca tgg gct gca gtc cag ggc atc gac acc ctt 192 Leu Ser Ala Phe Asn Ala Trp Ala Ala Val Gln Gly Ile Asp Thr Leu 50 55 60 tcc ctg cgc ctg gag cgc cac aac gaa aac gcc atc aag gtt gca gaa 240 Ser Leu Arg Leu Glu Arg His Asn Glu Asn Ala Ile Lys Val Ala Glu 65 70 75 80 ttc ctc aac aac cac gag aag gtg gaa aag gtt aac ttc gca ggc ctg 288 Phe Leu Asn Asn His Glu Lys Val Glu Lys Val Asn Phe Ala Gly Leu 85 90 95 aag gat tcc cct tgg tac gca acc aag gaa aag ctt ggc ctg aag tac 336 Lys Asp Ser Pro Trp Tyr Ala Thr Lys Glu Lys Leu Gly Leu Lys Tyr 100 105 110 acc ggc tcc gtt ctc acc ttc gag atc aag ggc ggc aag gat gag gct 384 Thr Gly Ser Val Leu Thr Phe Glu Ile Lys Gly Gly Lys Asp Glu Ala 115 120 125 tgg gca ttt atc gac gcc ctg aag cta cac tcc aac ctt gca aac atc 432 Trp Ala Phe Ile Asp Ala Leu Lys Leu His Ser Asn Leu Ala Asn Ile 130 135 140 ggc gat gtt cgc tcc ctc gtt gtt cac cca gca acc acc acc cat tca 480 Gly Asp Val Arg Ser Leu Val Val His Pro Ala Thr Thr Thr His Ser 145 150 155 160 cag tcc gac gaa gct ggc ctg gca cgc gcg ggc gtt acc cag tcc acc 528 Gln Ser Asp Glu Ala Gly Leu Ala Arg Ala Gly Val Thr Gln Ser Thr 165 170 175 gtc cgc ctg tcc gtt ggc atc gag acc att gat gat atc atc gct gac 576 Val Arg Leu Ser Val Gly Ile Glu Thr Ile Asp Asp Ile Ile Ala Asp 180 185 190 ctc gaa ggc ggc ttt gct gca atc tagctttaaa tagactcacc cca 623 Leu Glu Gly Gly Phe Ala Ala Ile 195 200 <210> 204 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 204 Thr Asp Glu Lys Asp Gly Lys Pro Val Leu Pro Tyr Phe Val Thr Pro 1 5 10 15 Asp Ala Ala Tyr His Gly Leu Lys Tyr Ala Asp Leu Gly Ala Pro Ala 20 25 30 Phe Gly Leu Lys Val Arg Val Gly Leu Leu Arg Asp Thr Gly Ser Thr 35 40 45 Leu Ser Ala Phe Asn Ala Trp Ala Ala Val Gln Gly Ile Asp Thr Leu 50 55 60 Ser Leu Arg Leu Glu Arg His Asn Glu Asn Ala Ile Lys Val Ala Glu 65 70 75 80 Phe Leu Asn Asn His Glu Lys Val Glu Lys Val Asn Phe Ala Gly Leu 85 90 95 Lys Asp Ser Pro Trp Tyr Ala Thr Lys Glu Lys Leu Gly Leu Lys Tyr 100 105 110 Thr Gly Ser Val Leu Thr Phe Glu Ile Lys Gly Gly Lys Asp Glu Ala 115 120 125 Trp Ala Phe Ile Asp Ala Leu Lys Leu His Ser Asn Leu Ala Asn Ile 130 135 140 Gly Asp Val Arg Ser Leu Val Val His Pro Ala Thr Thr Thr His Ser 145 150 155 160 Gln Ser Asp Glu Ala Gly Leu Ala Arg Ala Gly Val Thr Gln Ser Thr 165 170 175 Val Arg Leu Ser Val Gly Ile Glu Thr Ile Asp Asp Ile Ile Ala Asp 180 185 190 Leu Glu Gly Gly Phe Ala Ala Ile 195 200 <210> 205 <211> 599 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(576) <223> FRXA00402 <400> 205 gta ttg ccc tac ttc gtc act cca gat gct gct tac cac gga ttg aag 48 Val Leu Pro Tyr Phe Val Thr Pro Asp Ala Ala Tyr His Gly Leu Lys 1 5 10 15 tac gca gac ctt ggt gca cca gcc ttc ggc ctc aag gtt cgc gtt ggc 96 Tyr Ala Asp Leu Gly Ala Pro Ala Phe Gly Leu Lys Val Arg Val Gly 20 25 30 ctt cta cgc gac acc ggc tcc acc ctc tcc gca ttc aac gca tgg gct 144 Leu Leu Arg Asp Thr Gly Ser Thr Leu Ser Ala Phe Asn Ala Trp Ala 35 40 45 gca gtc cag ggc atc gac acc ctt tcc ctg cgc ctg gag cgc cac aac 192 Ala Val Gln Gly Ile Asp Thr Leu Ser Leu Arg Leu Glu Arg His Asn 50 55 60 gaa aac gcc atc aag gtt gca gaa ttc ctc aac aac cac gag aag gtg 240 Glu Asn Ala Ile Lys Val Ala Glu Phe Leu Asn Asn His Glu Lys Val 65 70 75 80 gaa aag gtt aac ttc gca ggc ctg aag gat tcc cct tgg tac gca acc 288 Glu Lys Val Asn Phe Ala Gly Leu Lys Asp Ser Pro Trp Tyr Ala Thr 85 90 95 aag gaa aag ctt ggc ctg aag tac acc ggc tcc gtt ctc acc ttc gag 336 Lys Glu Lys Leu Gly Leu Lys Tyr Thr Gly Ser Val Leu Thr Phe Glu 100 105 110 atc aag ggc ggc aag gat gag gct tgg gca ttt atc gac gcc ctg aag 384 Ile Lys Gly Gly Lys Asp Glu Ala Trp Ala Phe Ile Asp Ala Leu Lys 115 120 125 cta cac tcc aac ctt gca aac atc ggc gat gtt cgc tcc ctc gtt gtt 432 Leu His Ser Asn Leu Ala Asn Ile Gly Asp Val Arg Ser Leu Val Val 130 135 140 cac cca gca acc acc acc cat tca cag tcc gac gaa gct ggc ctg gca 480 His Pro Ala Thr Thr Thr His Ser Gln Ser Asp Glu Ala Gly Leu Ala 145 150 155 160 cgc gcg ggc gtt acc cag tcc acc gtc cgc ctg tcc gtt ggc atc gag 528 Arg Ala Gly Val Thr Gln Ser Thr Val Arg Leu Ser Val Gly Ile Glu 165 170 175 acc att gat gat atc atc gct gac ctc gaa ggc ggc ttt gct gca atc 576 Thr Ile Asp Asp Ile Ile Ala Asp Leu Glu Gly Gly Phe Ala Ala Ile 180 185 190 tagctttaaa tagactcacc cca 599 <210> 206 <211> 192 <212> PRT <213> Corynebacterium glutamicum <400> 206 Val Leu Pro Tyr Phe Val Thr Pro Asp Ala Ala Tyr His Gly Leu Lys 1 5 10 15 Tyr Ala Asp Leu Gly Ala Pro Ala Phe Gly Leu Lys Val Arg Val Gly 20 25 30 Leu Leu Arg Asp Thr Gly Ser Thr Leu Ser Ala Phe Asn Ala Trp Ala 35 40 45 Ala Val Gln Gly Ile Asp Thr Leu Ser Leu Arg Leu Glu Arg His Asn 50 55 60 Glu Asn Ala Ile Lys Val Ala Glu Phe Leu Asn Asn His Glu Lys Val 65 70 75 80 Glu Lys Val Asn Phe Ala Gly Leu Lys Asp Ser Pro Trp Tyr Ala Thr 85 90 95 Lys Glu Lys Leu Gly Leu Lys Tyr Thr Gly Ser Val Leu Thr Phe Glu 100 105 110 Ile Lys Gly Gly Lys Asp Glu Ala Trp Ala Phe Ile Asp Ala Leu Lys 115 120 125 Leu His Ser Asn Leu Ala Asn Ile Gly Asp Val Arg Ser Leu Val Val 130 135 140 His Pro Ala Thr Thr Thr His Ser Gln Ser Asp Glu Ala Gly Leu Ala 145 150 155 160 Arg Ala Gly Val Thr Gln Ser Thr Val Arg Leu Ser Val Gly Ile Glu 165 170 175 Thr Ile Asp Asp Ile Ile Ala Asp Leu Glu Gly Gly Phe Ala Ala Ile 180 185 190 <210> 207 <211> 613 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> RXA00405 <400> 207 agaataaatt tataccacac agtctattgc aatagaccaa gctgttcagt agggtgcatg 60 ggagaagaat ttcctaataa aaactcttaa ggacctccaa atg cca aag tac gac 115 Met Pro Lys Tyr Asp 1 5 aat tcc aat gct gac cag tgg ggc ttt gaa acc cgc tcc att cac gca 163 Asn Ser Asn Ala Asp Gln Trp Gly Phe Glu Thr Arg Ser Ile His Ala 10 15 20 ggc cag tca gta gac gca cag acc agc gca cga aac ctt ccg atc tac 211 Gly Gln Ser Val Asp Ala Gln Thr Ser Ala Arg Asn Leu Pro Ile Tyr 25 30 35 caa tcc acc gct ttc gtg ttc gac tcc gct gag cac gcc aag cag cgt 259 Gln Ser Thr Ala Phe Val Phe Asp Ser Ala Glu His Ala Lys Gln Arg 40 45 50 ttc gca ctt gag gat cta ggc cct gtt tac tcc cgc ctc acc aac cca 307 Phe Ala Leu Glu Asp Leu Gly Pro Val Tyr Ser Arg Leu Thr Asn Pro 55 60 65 acc gtt gag gct ttg gaa aac cgc atc gct tcc ctc gaa ggt ggc gtc 355 Thr Val Glu Ala Leu Glu Asn Arg Ile Ala Ser Leu Glu Gly Gly Val 70 75 80 85 cac gct gta gcg ttc tcc tcc gga cag gcc gca acc acc aac gcc att 403 His Ala Val Ala Phe Ser Ser Gly Gln Ala Ala Thr Thr Asn Ala Ile 90 95 100 ttg aac ctg gca gga gcg ggc gac cac atc gtc acc tcc cca cgc ctc 451 Leu Asn Leu Ala Gly Ala Gly Asp His Ile Val Thr Ser Pro Arg Leu 105 110 115 tac ggt ggc acc gag act cta ttc ctt atc act ctt aac cgc ctg ggt 499 Tyr Gly Gly Thr Glu Thr Leu Phe Leu Ile Thr Leu Asn Arg Leu Gly 120 125 130 atc gat gtt tcc ttc gtg gaa aac ccc gac gac cct gag tcc tgg cag 547 Ile Asp Val Ser Phe Val Glu Asn Pro Asp Asp Pro Glu Ser Trp Gln 135 140 145 gca gcc gtt cag cca aac acc aaa gca ttc ttc ggc gag act ttc gcc 595 Ala Ala Val Gln Pro Asn Thr Lys Ala Phe Phe Gly Glu Thr Phe Ala 150 155 160 165 aac cca cag gca gac gtc 613 Asn Pro Gln Ala Asp Val 170 <210> 208 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 208 Met Pro Lys Tyr Asp Asn Ser Asn Ala Asp Gln Trp Gly Phe Glu Thr 1 5 10 15 Arg Ser Ile His Ala Gly Gln Ser Val Asp Ala Gln Thr Ser Ala Arg 20 25 30 Asn Leu Pro Ile Tyr Gln Ser Thr Ala Phe Val Phe Asp Ser Ala Glu 35 40 45 His Ala Lys Gln Arg Phe Ala Leu Glu Asp Leu Gly Pro Val Tyr Ser 50 55 60 Arg Leu Thr Asn Pro Thr Val Glu Ala Leu Glu Asn Arg Ile Ala Ser 65 70 75 80 Leu Glu Gly Gly Val His Ala Val Ala Phe Ser Ser Gly Gln Ala Ala 85 90 95 Thr Thr Asn Ala Ile Leu Asn Leu Ala Gly Ala Gly Asp His Ile Val 100 105 110 Thr Ser Pro Arg Leu Tyr Gly Gly Thr Glu Thr Leu Phe Leu Ile Thr 115 120 125 Leu Asn Arg Leu Gly Ile Asp Val Ser Phe Val Glu Asn Pro Asp Asp 130 135 140 Pro Glu Ser Trp Gln Ala Ala Val Gln Pro Asn Thr Lys Ala Phe Phe 145 150 155 160 Gly Glu Thr Phe Ala Asn Pro Gln Ala Asp Val 165 170 <210> 209 <211> 551 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(528) <223> RXA02197 <400> 209 gcc gaa cgc atg cgc ttt agc ttc cca cgc cag cag cgc ggc agg ttc 48 Ala Glu Arg Met Arg Phe Ser Phe Pro Arg Gln Gln Arg Gly Arg Phe 1 5 10 15 ttg tgc atc gcg gat ttc att cgc cca cgc gag caa gct gtc aag gac 96 Leu Cys Ile Ala Asp Phe Ile Arg Pro Arg Glu Gln Ala Val Lys Asp 20 25 30 ggc caa gtg gac gtc atg cca ttc cag ctg gtc acc atg ggt aat cct 144 Gly Gln Val Asp Val Met Pro Phe Gln Leu Val Thr Met Gly Asn Pro 35 40 45 att gct gat ttc gcc aac gag ttg ttc gca gcc aat gaa tac cgc gag 192 Ile Ala Asp Phe Ala Asn Glu Leu Phe Ala Ala Asn Glu Tyr Arg Glu 50 55 60 tac ttg gaa gtt cac ggc atc ggc gtg cag ctc acc gaa gca ttg gcc 240 Tyr Leu Glu Val His Gly Ile Gly Val Gln Leu Thr Glu Ala Leu Ala 65 70 75 80 gag tac tgg cac tcc cga gtg cgc agc gaa ctc aag ctg aac gac ggt 288 Glu Tyr Trp His Ser Arg Val Arg Ser Glu Leu Lys Leu Asn Asp Gly 85 90 95 gga tct gtc gct gat ttt gat cca gaa gac aag acc aag ttc ttc gac 336 Gly Ser Val Ala Asp Phe Asp Pro Glu Asp Lys Thr Lys Phe Phe Asp 100 105 110 ctg gat tac cgc ggc gcc cgc ttc tcc ttt ggt tac ggt tct tgc cct 384 Leu Asp Tyr Arg Gly Ala Arg Phe Ser Phe Gly Tyr Gly Ser Cys Pro 115 120 125 gat ctg gaa gac cgc gca aag ctg gtg gaa ttg ctc gag cca ggc cgt 432 Asp Leu Glu Asp Arg Ala Lys Leu Val Glu Leu Leu Glu Pro Gly Arg 130 135 140 atc ggc gtg gag ttg tcc gag gaa ctc cag ctg cac cca gag cag tcc 480 Ile Gly Val Glu Leu Ser Glu Glu Leu Gln Leu His Pro Glu Gln Ser 145 150 155 160 aca gac gcg ttt gtg ctc tac cac cca gag gca aag tac ttt aac gtc 528 Thr Asp Ala Phe Val Leu Tyr His Pro Glu Ala Lys Tyr Phe Asn Val 165 170 175 taacaccttt gagagggaaa act 551 <210> 210 <211> 176 <212> PRT <213> Corynebacterium glutamicum <400> 210 Ala Glu Arg Met Arg Phe Ser Phe Pro Arg Gln Gln Arg Gly Arg Phe 1 5 10 15 Leu Cys Ile Ala Asp Phe Ile Arg Pro Arg Glu Gln Ala Val Lys Asp 20 25 30 Gly Gln Val Asp Val Met Pro Phe Gln Leu Val Thr Met Gly Asn Pro 35 40 45 Ile Ala Asp Phe Ala Asn Glu Leu Phe Ala Ala Asn Glu Tyr Arg Glu 50 55 60 Tyr Leu Glu Val His Gly Ile Gly Val Gln Leu Thr Glu Ala Leu Ala 65 70 75 80 Glu Tyr Trp His Ser Arg Val Arg Ser Glu Leu Lys Leu Asn Asp Gly 85 90 95 Gly Ser Val Ala Asp Phe Asp Pro Glu Asp Lys Thr Lys Phe Phe Asp 100 105 110 Leu Asp Tyr Arg Gly Ala Arg Phe Ser Phe Gly Tyr Gly Ser Cys Pro 115 120 125 Asp Leu Glu Asp Arg Ala Lys Leu Val Glu Leu Leu Glu Pro Gly Arg 130 135 140 Ile Gly Val Glu Leu Ser Glu Glu Leu Gln Leu His Pro Glu Gln Ser 145 150 155 160 Thr Asp Ala Phe Val Leu Tyr His Pro Glu Ala Lys Tyr Phe Asn Val 165 170 175 <210> 211 <211> 2599 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2599) <223> RXN02198 <400> 211 agactagtgg cgctttgcct gtgttgctta ggcggcgttg aaaatgaact acgaatgaaa 60 agttcgggaa ttgtctaatc cgtactaagc tgtctacaca atg tct act tca gtt 115 Met Ser Thr Ser Val 1 5 act tca cca gcc cac aac aac gca cat tcc tcc gaa ttt ttg gat gcg 163 Thr Ser Pro Ala His Asn Asn Ala His Ser Ser Glu Phe Leu Asp Ala 10 15 20 ttg gca aac cat gtg ttg atc ggc gac ggc gcc atg ggc acc cag ctc 211 Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala Met Gly Thr Gln Leu 25 30 35 caa ggc ttt gac ctg gac gtg gaa aag gat ttc ctt gat ctg gag ggg 259 Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe Leu Asp Leu Glu Gly 40 45 50 tgt aat gag att ctc aac gac acc cgc cct gat gtg ttg agg cag att 307 Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp Val Leu Arg Gln Ile 55 60 65 cac cgc gcc tac ttt gag gcg gga gct gac ttg gtt gag acc aat act 355 His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu Val Glu Thr Asn Thr 70 75 80 85 ttt ggt tgc aac ctg ccg aac ttg gcg gat tat gac atc gct gat cgt 403 Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr Asp Ile Ala Asp Arg 90 95 100 tgc cgt gag ctt gcc tac aag ggc act gca gtg gct agg gaa gtg gct 451 Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val Ala Arg Glu Val Ala 105 110 115 gat gag atg ggg ccg ggc cga aac ggc atg cgg cgt ttc gtg gtt ggt 499 Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg Arg Phe Val Val Gly 120 125 130 tcc ctg gga cct gga acg aag ctt cca tcg ctg ggc cat gca ccg tat 547 Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu Gly His Ala Pro Tyr 135 140 145 gca gat ttg cgt ggg cac tac aag gaa gca gcg ctt ggc atc atc gac 595 Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala Leu Gly Ile Ile Asp 150 155 160 165 ggt ggt ggc gat gcc ttt ttg att gag act gct cag gac ttg ctt cag 643 Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala Gln Asp Leu Leu Gln 170 175 180 gtc aag gct gcg gtt cac ggc gtt caa gat gcc atg gct gaa ctt gat 691 Val Lys Ala Ala Val His Gly Val Gln Asp Ala Met Ala Glu Leu Asp 185 190 195 aca ttc ttg ccc att att tgc cac gtc acc gta gag acc acc ggc acc 739 Thr Phe Leu Pro Ile Ile Cys His Val Thr Val Glu Thr Thr Gly Thr 200 205 210 atg ctc atg ggt tct gag atc ggt gcc gcg ttg aca gcg ctg cag cca 787 Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu Thr Ala Leu Gln Pro 215 220 225 ctg ggt atc gac atg att ggt ctg aac tgc gcc acc ggc cca gat gag 835 Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala Thr Gly Pro Asp Glu 230 235 240 245 atg agc gag cac ctg cgt tac ctg tcc aag cac gcc gat att cct gtg 883 Met Ser Glu His Leu Arg Tyr Leu Ser Lys His Ala Asp Ile Pro Val 250 255 260 tcg gtg atg cct aac gca ggt ctt cct gtc ctg ggt aaa aac ggt gca 931 Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu Gly Lys Asn Gly Ala 265 270 275 gaa tac cca ctt gag gct gag gat ttg gcg cag gcg ctg gct gga ttc 979 Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln Ala Leu Ala Gly Phe 280 285 290 gtc tcc gaa tat ggc ctg tcc atg gtg ggt ggt tgt tgt ggc acc aca 1027 Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly Cys Cys Gly Thr Thr 295 300 305 cct gag cac atc cgt gcg gtc cgc gat gcg gtg gtt ggt gtt cca gag 1075 Pro Glu His Ile Arg Ala Val Arg Asp Ala Val Val Gly Val Pro Glu 310 315 320 325 cag gaa acc tcc aca ctg acc aag atc cct gca ggc cct gtt gag cag 1123 Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala Gly Pro Val Glu Gln 330 335 340 gcc tcc cgc gag gtg gag aaa gag gac tcc gtc gcg tcg ctg tac acc 1171 Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val Ala Ser Leu Tyr Thr 345 350 355 tcg gtg cca ttg tcc cag gaa acc ggc att tcc atg atc ggt gag cgc 1219 Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser Met Ile Gly Glu Arg 360 365 370 acc aac tcc aac ggt tcc aag gca ttc cgt gag gca atg ctg tct ggc 1267 Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu Ala Met Leu Ser Gly 375 380 385 gat tgg gaa aag tgt gtg gat att gcc aag cag caa acc cgc gat ggt 1315 Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln Gln Thr Arg Asp Gly 390 395 400 405 gca cac atg ctg gat ctt tgt gtg gat tac gtg gga cga gac ggc acc 1363 Ala His Met Leu Asp Leu Cys Val Asp Tyr Val Gly Arg Asp Gly Thr 410 415 420 gcc gat atg gcg acc ttg gca gca ctt ctt gct acc agc tcc act ttg 1411 Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala Thr Ser Ser Thr Leu 425 430 435 cca atc atg att gac tcc acc gag cca gag gtt att cgc aca ggc ctt 1459 Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val Ile Arg Thr Gly Leu 440 445 450 gag cac ttg ggt gga cga agc atc gtt aac tcc gtc aac ttt gaa gac 1507 Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser Val Asn Phe Glu Asp 455 460 465 ggc gat ggc cct gag tcc cgc tac cag cgc atc atg aaa ctg gta aag 1555 Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile Met Lys Leu Val Lys 470 475 480 485 cag cac ggt gcg gcc gtg gtt gcg ctg acc att gat gag gaa ggc cag 1603 Gln His Gly Ala Ala Val Val Ala Leu Thr Ile Asp Glu Glu Gly Gln 490 495 500 gca cgt acc gct gag cac aag gtg cgc att gct aaa cga ctg att gac 1651 Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala Lys Arg Leu Ile Asp 505 510 515 gat atc acc ggc agc tac ggc ctg gat atc aaa gac atc gtt gtg gac 1699 Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys Asp Ile Val Val Asp 520 525 530 tgc ctg acc ttc ccg atc tct act ggc cag gaa gaa acc agg cga gat 1747 Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu Glu Thr Arg Arg Asp 535 540 545 ggc att gaa acc atc gaa gcc atc cgc gag ctg aag aag ctc tac cca 1795 Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu Lys Lys Leu Tyr Pro 550 555 560 565 gaa atc cac acc acc ctg ggt ctg tcc aat att tcc ttc ggc ctg aac 1843 Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile Ser Phe Gly Leu Asn 570 575 580 cct gct gca cgc cag gtt ctt aac tct gtg ttc ctc aat gag tgc att 1891 Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe Leu Asn Glu Cys Ile 585 590 595 gag gct ggt ctg gac tct gcg att gcg cac agc tcc aag att ttg ccg 1939 Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser Ser Lys Ile Leu Pro 600 605 610 atg aac cgc att gat gat cgc cag cgc gaa gtg gcg ttg gat atg gtc 1987 Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val Ala Leu Asp Met Val 615 620 625 tat gat cgc cgc acc gag gat tac gat ccg ctg cag gaa ttc atg cag 2035 Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu Gln Glu Phe Met Gln 630 635 640 645 ctg ttt gag ggc gtt tct gct gcc gat gcc aag gat gct cgc gct gaa 2083 Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys Asp Ala Arg Ala Glu 650 655 660 cag ctg gcc gct atg cct ttg ttt gag cgt ttg gca cag cgc atc atc 2131 Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu Ala Gln Arg Ile Ile 665 670 675 gac ggc gat aag aat ggc ctt gag gat gat ctg gaa gca ggc atg aag 2179 Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu Glu Ala Gly Met Lys 680 685 690 gag aag tct cct att gcg atc atc aac gag gac ctt ctc aac ggc atg 2227 Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp Leu Leu Asn Gly Met 695 700 705 aag acc gtg ggt gag ctg ttt ggt tcc gga cag atg cag ctg cca ttc 2275 Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln Met Gln Leu Pro Phe 710 715 720 725 gtg ctg caa tcg gca gaa acc atg aaa act gcg gtg gcc tat ttg gaa 2323 Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala Val Ala Tyr Leu Glu 730 735 740 ccg ttc atg gaa gag gaa gca gaa gct acc gga tct gcg cag gca gag 2371 Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly Ser Ala Gln Ala Glu 745 750 755 ggc aag ggc aaa atc gtc gtg gcc acc gtc aag ggt gac gtg cac gat 2419 Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys Gly Asp Val His Asp 760 765 770 atc ggc aag aac ttg gtg gac atc att ttg tcc aac aac ggt tac gac 2467 Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser Asn Asn Gly Tyr Asp 775 780 785 gtg gtg aac ttg ggc atc aag cag cca ctg tcc gcc atg ttg gaa gca 2515 Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser Ala Met Leu Glu Ala 790 795 800 805 gcg gaa gaa cac aaa gca gac gtc atc ggc atg tcg gga ctt ctt gtg 2563 Ala Glu Glu His Lys Ala Asp Val Ile Gly Met Ser Gly Leu Leu Val 810 815 820 aag tcc acc gtg gtg atg aag caa acc atc agc gac 2599 Lys Ser Thr Val Val Met Lys Gln Thr Ile Ser Asp 825 830 <210> 212 <211> 833 <212> PRT <213> Corynebacterium glutamicum <400> 212 Met Ser Thr Ser Val Thr Ser Pro Ala His Asn Asn Ala His Ser Ser 1 5 10 15 Glu Phe Leu Asp Ala Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala 20 25 30 Met Gly Thr Gln Leu Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe 35 40 45 Leu Asp Leu Glu Gly Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp 50 55 60 Val Leu Arg Gln Ile His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu 65 70 75 80 Val Glu Thr Asn Thr Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr 85 90 95 Asp Ile Ala Asp Arg Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val 100 105 110 Ala Arg Glu Val Ala Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg 115 120 125 Arg Phe Val Val Gly Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu 130 135 140 Gly His Ala Pro Tyr Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala 145 150 155 160 Leu Gly Ile Ile Asp Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala 165 170 175 Gln Asp Leu Leu Gln Val Lys Ala Ala Val His Gly Val Gln Asp Ala 180 185 190 Met Ala Glu Leu Asp Thr Phe Leu Pro Ile Ile Cys His Val Thr Val 195 200 205 Glu Thr Thr Gly Thr Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu 210 215 220 Thr Ala Leu Gln Pro Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala 225 230 235 240 Thr Gly Pro Asp Glu Met Ser Glu His Leu Arg Tyr Leu Ser Lys His 245 250 255 Ala Asp Ile Pro Val Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu 260 265 270 Gly Lys Asn Gly Ala Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln 275 280 285 Ala Leu Ala Gly Phe Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly 290 295 300 Cys Cys Gly Thr Thr Pro Glu His Ile Arg Ala Val Arg Asp Ala Val 305 310 315 320 Val Gly Val Pro Glu Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala 325 330 335 Gly Pro Val Glu Gln Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val 340 345 350 Ala Ser Leu Tyr Thr Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser 355 360 365 Met Ile Gly Glu Arg Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu 370 375 380 Ala Met Leu Ser Gly Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln 385 390 395 400 Gln Thr Arg Asp Gly Ala His Met Leu Asp Leu Cys Val Asp Tyr Val 405 410 415 Gly Arg Asp Gly Thr Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala 420 425 430 Thr Ser Ser Thr Leu Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val 435 440 445 Ile Arg Thr Gly Leu Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser 450 455 460 Val Asn Phe Glu Asp Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile 465 470 475 480 Met Lys Leu Val Lys Gln His Gly Ala Ala Val Val Ala Leu Thr Ile 485 490 495 Asp Glu Glu Gly Gln Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala 500 505 510 Lys Arg Leu Ile Asp Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys 515 520 525 Asp Ile Val Val Asp Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu 530 535 540 Glu Thr Arg Arg Asp Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu 545 550 555 560 Lys Lys Leu Tyr Pro Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile 565 570 575 Ser Phe Gly Leu Asn Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe 580 585 590 Leu Asn Glu Cys Ile Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser 595 600 605 Ser Lys Ile Leu Pro Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val 610 615 620 Ala Leu Asp Met Val Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu 625 630 635 640 Gln Glu Phe Met Gln Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys 645 650 655 Asp Ala Arg Ala Glu Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu 660 665 670 Ala Gln Arg Ile Ile Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu 675 680 685 Glu Ala Gly Met Lys Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp 690 695 700 Leu Leu Asn Gly Met Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln 705 710 715 720 Met Gln Leu Pro Phe Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala 725 730 735 Val Ala Tyr Leu Glu Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly 740 745 750 Ser Ala Gln Ala Glu Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys 755 760 765 Gly Asp Val His Asp Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser 770 775 780 Asn Asn Gly Tyr Asp Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser 785 790 795 800 Ala Met Leu Glu Ala Ala Glu Glu His Lys Ala Asp Val Ile Gly Met 805 810 815 Ser Gly Leu Leu Val Lys Ser Thr Val Val Met Lys Gln Thr Ile Ser 820 825 830 Asp <210> 213 <211> 2578 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2578) <223> FRXA02198 <400> 213 agactagtgg cgctttgcct gtgttgctta ggcggcgttg aaaatgaact acgaatgaaa 60 agttcgggaa ttgtctaatc cgtactaagc tgtctacaca atg tct act tca gtt 115 Met Ser Thr Ser Val 1 5 act tca cca gcc cac aac aac gca cat tcc tcc gaa ttt ttg gat gcg 163 Thr Ser Pro Ala His Asn Asn Ala His Ser Ser Glu Phe Leu Asp Ala 10 15 20 ttg gca aac cat gtg ttg atc ggc gac ggc gcc atg ggc acc cag ctc 211 Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala Met Gly Thr Gln Leu 25 30 35 caa ggc ttt gac ctg gac gtg gaa aag gat ttc ctt gat ctg gag ggg 259 Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe Leu Asp Leu Glu Gly 40 45 50 tgt aat gag att ctc aac gac acc cgc cct gat gtg ttg agg cag att 307 Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp Val Leu Arg Gln Ile 55 60 65 cac cgc gcc tac ttt gag gcg gga gct gac ttg gtt gag acc aat act 355 His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu Val Glu Thr Asn Thr 70 75 80 85 ttt ggt tgc aac ctg ccg aac ttg gcg gat tat gac atc gct gat cgt 403 Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr Asp Ile Ala Asp Arg 90 95 100 tgc cgt gag ctt gcc tac aag ggc act gca gtg gct agg gaa gtg gct 451 Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val Ala Arg Glu Val Ala 105 110 115 gat gag atg ggg ccg ggc cga aac ggc atg cgg cgt ttc gtg gtt ggt 499 Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg Arg Phe Val Val Gly 120 125 130 tcc ctg gga cct gga acg aag ctt cca tcg ctg ggc cat gca ccg tat 547 Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu Gly His Ala Pro Tyr 135 140 145 gca gat ttg cgt ggg cac tac aag gaa gca gcg ctt ggc atc atc gac 595 Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala Leu Gly Ile Ile Asp 150 155 160 165 ggt ggt ggc gat gcc ttt ttg att gag act gct cag gac ttg ctt cag 643 Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala Gln Asp Leu Leu Gln 170 175 180 gtc aag gct gcg gtt cac ggc gtt caa gat gcc atg gct gaa ctt gat 691 Val Lys Ala Ala Val His Gly Val Gln Asp Ala Met Ala Glu Leu Asp 185 190 195 aca ttc ttg ccc att att tgc cac gtc acc gta gag acc acc ggc acc 739 Thr Phe Leu Pro Ile Ile Cys His Val Thr Val Glu Thr Thr Gly Thr 200 205 210 atg ctc atg ggt tct gag atc ggt gcc gcg ttg aca gcg ctg cag cca 787 Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu Thr Ala Leu Gln Pro 215 220 225 ctg ggt atc gac atg att ggt ctg aac tgc gcc acc ggc cca gat gag 835 Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala Thr Gly Pro Asp Glu 230 235 240 245 atg agc gag cac ctg cgt tac ctg tcc aag cac gcc gat att cct gtg 883 Met Ser Glu His Leu Arg Tyr Leu Ser Lys His Ala Asp Ile Pro Val 250 255 260 tcg gtg atg cct aac gca ggt ctt cct gtc ctg ggt aaa aac ggt gca 931 Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu Gly Lys Asn Gly Ala 265 270 275 gaa tac cca ctt gag gct gag gat ttg gcg cag gcg ctg gct gga ttc 979 Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln Ala Leu Ala Gly Phe 280 285 290 gtc tcc gaa tat ggc ctg tcc atg gtg ggt ggt tgt tgt ggc acc aca 1027 Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly Cys Cys Gly Thr Thr 295 300 305 cct gag cac atc cgt gcg gtc cgc gat gcg gtg gtt ggt gtt cca gag 1075 Pro Glu His Ile Arg Ala Val Arg Asp Ala Val Val Gly Val Pro Glu 310 315 320 325 cag gaa acc tcc aca ctg acc aag atc cct gca ggc cct gtt gag cag 1123 Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala Gly Pro Val Glu Gln 330 335 340 gcc tcc cgc gag gtg gag aaa gag gac tcc gtc gcg tcg ctg tac acc 1171 Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val Ala Ser Leu Tyr Thr 345 350 355 tcg gtg cca ttg tcc cag gaa acc ggc att tcc atg atc ggt gag cgc 1219 Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser Met Ile Gly Glu Arg 360 365 370 acc aac tcc aac ggt tcc aag gca ttc cgt gag gca atg ctg tct ggc 1267 Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu Ala Met Leu Ser Gly 375 380 385 gat tgg gaa aag tgt gtg gat att gcc aag cag caa acc cgc gat ggt 1315 Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln Gln Thr Arg Asp Gly 390 395 400 405 gca cac atg ctg gat ctt tgt gtg gat tac gtg gga cga gac ggc acc 1363 Ala His Met Leu Asp Leu Cys Val Asp Tyr Val Gly Arg Asp Gly Thr 410 415 420 gcc gat atg gcg acc ttg gca gca ctt ctt gct acc agc tcc act ttg 1411 Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala Thr Ser Ser Thr Leu 425 430 435 cca atc atg att gac tcc acc gag cca gag gtt att cgc aca ggc ctt 1459 Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val Ile Arg Thr Gly Leu 440 445 450 gag cac ttg ggt gga cga agc atc gtt aac tcc gtc aac ttt gaa gac 1507 Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser Val Asn Phe Glu Asp 455 460 465 ggc gat ggc cct gag tcc cgc tac cag cgc atc atg aaa ctg gta aag 1555 Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile Met Lys Leu Val Lys 470 475 480 485 cag cac ggt gcg gcc gtg gtt gcg ctg acc att gat gag gaa ggc cag 1603 Gln His Gly Ala Ala Val Val Ala Leu Thr Ile Asp Glu Glu Gly Gln 490 495 500 gca cgt acc gct gag cac aag gtg cgc att gct aaa cga ctg att gac 1651 Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala Lys Arg Leu Ile Asp 505 510 515 gat atc acc ggc agc tac ggc ctg gat atc aaa gac atc gtt gtg gac 1699 Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys Asp Ile Val Val Asp 520 525 530 tgc ctg acc ttc ccg atc tct act ggc cag gaa gaa acc agg cga gat 1747 Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu Glu Thr Arg Arg Asp 535 540 545 ggc att gaa acc atc gaa gcc atc cgc gag ctg aag aag ctc tac cca 1795 Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu Lys Lys Leu Tyr Pro 550 555 560 565 gaa atc cac acc acc ctg ggt ctg tcc aat att tcc ttc ggc ctg aac 1843 Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile Ser Phe Gly Leu Asn 570 575 580 cct gct gca cgc cag gtt ctt aac tct gtg ttc ctc aat gag tgc att 1891 Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe Leu Asn Glu Cys Ile 585 590 595 gag gct ggt ctg gac tct gcg att gcg cac agc tcc aag att ttg ccg 1939 Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser Ser Lys Ile Leu Pro 600 605 610 atg aac cgc att gat gat cgc cag cgc gaa gtg gcg ttg gat atg gtc 1987 Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val Ala Leu Asp Met Val 615 620 625 tat gat cgc cgc acc gag gat tac gat ccg ctg cag gaa ttc atg cag 2035 Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu Gln Glu Phe Met Gln 630 635 640 645 ctg ttt gag ggc gtt tct gct gcc gat gcc aag gat gct cgc gct gaa 2083 Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys Asp Ala Arg Ala Glu 650 655 660 cag ctg gcc gct atg cct ttg ttt gag cgt ttg gca cag cgc atc atc 2131 Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu Ala Gln Arg Ile Ile 665 670 675 gac ggc gat aag aat ggc ctt gag gat gat ctg gaa gca ggc atg aag 2179 Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu Glu Ala Gly Met Lys 680 685 690 gag aag tct cct att gcg atc atc aac gag gac ctt ctc aac ggc atg 2227 Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp Leu Leu Asn Gly Met 695 700 705 aag acc gtg ggt gag ctg ttt ggt tcc gga cag atg cag ctg cca ttc 2275 Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln Met Gln Leu Pro Phe 710 715 720 725 gtg ctg caa tcg gca gaa acc atg aaa act gcg gtg gcc tat ttg gaa 2323 Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala Val Ala Tyr Leu Glu 730 735 740 ccg ttc atg gaa gag gaa gca gaa gct acc gga tct gcg cag gca gag 2371 Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly Ser Ala Gln Ala Glu 745 750 755 ggc aag ggc aaa atc gtc gtg gcc acc gtc aag ggt gac gtg cac gat 2419 Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys Gly Asp Val His Asp 760 765 770 atc ggc aag aac ttg gtg gac atc att ttg tcc aac aac ggt tac gac 2467 Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser Asn Asn Gly Tyr Asp 775 780 785 gtg gtg aac ttg ggc atc aag cag cca ctg tcc gcc atg ttg gaa gca 2515 Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser Ala Met Leu Glu Ala 790 795 800 805 gcg gaa gaa cac aaa gca gac gtc atc ggc atg tcg gga ctt ctt gtg 2563 Ala Glu Glu His Lys Ala Asp Val Ile Gly Met Ser Gly Leu Leu Val 810 815 820 aag tcc acc gtg gtg 2578 Lys Ser Thr Val Val 825 <210> 214 <211> 826 <212> PRT <213> Corynebacterium glutamicum <400> 214 Met Ser Thr Ser Val Thr Ser Pro Ala His Asn Asn Ala His Ser Ser 1 5 10 15 Glu Phe Leu Asp Ala Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala 20 25 30 Met Gly Thr Gln Leu Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe 35 40 45 Leu Asp Leu Glu Gly Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp 50 55 60 Val Leu Arg Gln Ile His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu 65 70 75 80 Val Glu Thr Asn Thr Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr 85 90 95 Asp Ile Ala Asp Arg Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val 100 105 110 Ala Arg Glu Val Ala Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg 115 120 125 Arg Phe Val Val Gly Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu 130 135 140 Gly His Ala Pro Tyr Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala 145 150 155 160 Leu Gly Ile Ile Asp Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala 165 170 175 Gln Asp Leu Leu Gln Val Lys Ala Ala Val His Gly Val Gln Asp Ala 180 185 190 Met Ala Glu Leu Asp Thr Phe Leu Pro Ile Ile Cys His Val Thr Val 195 200 205 Glu Thr Thr Gly Thr Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu 210 215 220 Thr Ala Leu Gln Pro Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala 225 230 235 240 Thr Gly Pro Asp Glu Met Ser Glu His Leu Arg Tyr Leu Ser Lys His 245 250 255 Ala Asp Ile Pro Val Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu 260 265 270 Gly Lys Asn Gly Ala Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln 275 280 285 Ala Leu Ala Gly Phe Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly 290 295 300 Cys Cys Gly Thr Thr Pro Glu His Ile Arg Ala Val Arg Asp Ala Val 305 310 315 320 Val Gly Val Pro Glu Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala 325 330 335 Gly Pro Val Glu Gln Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val 340 345 350 Ala Ser Leu Tyr Thr Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser 355 360 365 Met Ile Gly Glu Arg Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu 370 375 380 Ala Met Leu Ser Gly Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln 385 390 395 400 Gln Thr Arg Asp Gly Ala His Met Leu Asp Leu Cys Val Asp Tyr Val 405 410 415 Gly Arg Asp Gly Thr Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala 420 425 430 Thr Ser Ser Thr Leu Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val 435 440 445 Ile Arg Thr Gly Leu Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser 450 455 460 Val Asn Phe Glu Asp Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile 465 470 475 480 Met Lys Leu Val Lys Gln His Gly Ala Ala Val Val Ala Leu Thr Ile 485 490 495 Asp Glu Glu Gly Gln Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala 500 505 510 Lys Arg Leu Ile Asp Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys 515 520 525 Asp Ile Val Val Asp Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu 530 535 540 Glu Thr Arg Arg Asp Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu 545 550 555 560 Lys Lys Leu Tyr Pro Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile 565 570 575 Ser Phe Gly Leu Asn Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe 580 585 590 Leu Asn Glu Cys Ile Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser 595 600 605 Ser Lys Ile Leu Pro Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val 610 615 620 Ala Leu Asp Met Val Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu 625 630 635 640 Gln Glu Phe Met Gln Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys 645 650 655 Asp Ala Arg Ala Glu Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu 660 665 670 Ala Gln Arg Ile Ile Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu 675 680 685 Glu Ala Gly Met Lys Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp 690 695 700 Leu Leu Asn Gly Met Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln 705 710 715 720 Met Gln Leu Pro Phe Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala 725 730 735 Val Ala Tyr Leu Glu Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly 740 745 750 Ser Ala Gln Ala Glu Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys 755 760 765 Gly Asp Val His Asp Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser 770 775 780 Asn Asn Gly Tyr Asp Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser 785 790 795 800 Ala Met Leu Glu Ala Ala Glu Glu His Lys Ala Asp Val Ile Gly Met 805 810 815 Ser Gly Leu Leu Val Lys Ser Thr Val Val 820 825 <210> 215 <211> 621 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(598) <223> RXN03074 <400> 215 tttgtgggca atctggtttt ttcgtaattg tgtgggatga atctcttaaa aattcacatt 60 tagcaggaca agcatactgt tttagttcta tgctgtgggc atg act caa agt gct 115 Met Thr Gln Ser Ala 1 5 cca gaa ttc att gcc acc gca gac ctc gta gac atc atc ggc gac aac 163 Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp Ile Ile Gly Asp Asn 10 15 20 gcg caa tca tgc gac act cag ttt caa aac ctt gga ggt gcc aca gaa 211 Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu Gly Gly Ala Thr Glu 25 30 35 ttc cac gga ata ata acc acc gtg aaa tgc ttc caa gac aac gcc ctc 259 Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe Gln Asp Asn Ala Leu 40 45 50 ctg aaa tcc atc ctg agc gag gat aat cct ggg gga gtg ctg gtt atc 307 Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly Gly Val Leu Val Ile 55 60 65 gat ggc gac gca tcc gtg cac acc gcg cta gtt ggc gac atc att gca 355 Asp Gly Asp Ala Ser Val His Thr Ala Leu Val Gly Asp Ile Ile Ala 70 75 80 85 gga ctt gga aaa gat cat ggt tgg tcc gga gta att gtc aac gga gca 403 Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val Ile Val Asn Gly Ala 90 95 100 att cga gac tcc gca gtc atc ggc acc atg acc ttt ggt tgt aaa gcc 451 Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr Phe Gly Cys Lys Ala 105 110 115 ctt gga acc aac ccg cgg aaa tcc act aaa act ggt tcc ggc gaa cga 499 Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr Gly Ser Gly Glu Arg 120 125 130 gac gta gtg gta tcg att ggt ggc att gac ttc att cct ggt cat tac 547 Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe Ile Pro Gly His Tyr 135 140 145 gtc tac gcg gac tct gac gga att atc gtc acc gag gcg cca att aag 595 Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr Glu Ala Pro Ile Lys 150 155 160 165 cag taatttgttt tgacgacgca gta 621 Gln <210> 216 <211> 166 <212> PRT <213> Corynebacterium glutamicum <400> 216 Met Thr Gln Ser Ala Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp 1 5 10 15 Ile Ile Gly Asp Asn Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu 20 25 30 Gly Gly Ala Thr Glu Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe 35 40 45 Gln Asp Asn Ala Leu Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly 50 55 60 Gly Val Leu Val Ile Asp Gly Asp Ala Ser Val His Thr Ala Leu Val 65 70 75 80 Gly Asp Ile Ile Ala Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val 85 90 95 Ile Val Asn Gly Ala Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr 100 105 110 Phe Gly Cys Lys Ala Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr 115 120 125 Gly Ser Gly Glu Arg Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe 130 135 140 Ile Pro Gly His Tyr Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr 145 150 155 160 Glu Ala Pro Ile Lys Gln 165 <210> 217 <211> 621 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(598) <223> FRXA02906 <400> 217 tttgtgggca atctggtttt ttcgtaattg tgtgggatga atctcttaaa aattcacatt 60 tagcaggaca agcatactgt tttagttcta tgctgtgggc atg act caa agt gct 115 Met Thr Gln Ser Ala 1 5 cca gaa ttc att gcc acc gca gac ctc gta gac atc atc ggc gac aac 163 Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp Ile Ile Gly Asp Asn 10 15 20 gcg caa tca tgc gac act cag ttt caa aac ctt gga ggt gcc aca gaa 211 Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu Gly Gly Ala Thr Glu 25 30 35 ttc cac gga ata ata acc acc gtg aaa tgc ttc caa gac aac gcc ctc 259 Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe Gln Asp Asn Ala Leu 40 45 50 ctg aaa tcc atc ctg agc gag gat aat cct ggg gga gtg ctg gtt atc 307 Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly Gly Val Leu Val Ile 55 60 65 gat ggc gac gca tcc gtg cac acc gcg cta gtt ggc gac atc att gca 355 Asp Gly Asp Ala Ser Val His Thr Ala Leu Val Gly Asp Ile Ile Ala 70 75 80 85 gga ctt gga aaa gat cat ggt tgg tcc gga gta att gtc aac gga gca 403 Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val Ile Val Asn Gly Ala 90 95 100 att cga gac tcc gca gtc atc ggc acc atg acc ttt ggt tgt aaa gcc 451 Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr Phe Gly Cys Lys Ala 105 110 115 ctt gga acc aac ccg cgg aaa tcc act aaa act ggt tcc ggc gaa cga 499 Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr Gly Ser Gly Glu Arg 120 125 130 gac gta gtg gta tcg att ggt ggc att gac ttc att cct ggt cat tac 547 Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe Ile Pro Gly His Tyr 135 140 145 gtc tac gcg gac tct gac gga att atc gtc acc gag gcg cca att aag 595 Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr Glu Ala Pro Ile Lys 150 155 160 165 cag taatttgttt tgacgacgca gta 621 Gln <210> 218 <211> 166 <212> PRT <213> Corynebacterium glutamicum <400> 218 Met Thr Gln Ser Ala Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp 1 5 10 15 Ile Ile Gly Asp Asn Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu 20 25 30 Gly Gly Ala Thr Glu Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe 35 40 45 Gln Asp Asn Ala Leu Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly 50 55 60 Gly Val Leu Val Ile Asp Gly Asp Ala Ser Val His Thr Ala Leu Val 65 70 75 80 Gly Asp Ile Ile Ala Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val 85 90 95 Ile Val Asn Gly Ala Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr 100 105 110 Phe Gly Cys Lys Ala Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr 115 120 125 Gly Ser Gly Glu Arg Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe 130 135 140 Ile Pro Gly His Tyr Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr 145 150 155 160 Glu Ala Pro Ile Lys Gln 165 <210> 219 <211> 1557 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1534) <223> RXN00132 <400> 219 aacagcttca atcaattcgg tgtccactcc aacatgtaga gtggtgcgcg ttaaaaaagt 60 tttcctaatt ttcattttct taaaaggagc tcgccaggac atg gca cag gtt atg 115 Met Ala Gln Val Met 1 5 gac ttc aag gtt gcc gat ctt tca cta gca gag gca gga cgt cac cag 163 Asp Phe Lys Val Ala Asp Leu Ser Leu Ala Glu Ala Gly Arg His Gln 10 15 20 att cgt ctt gca gag tat gag atg cca ggt ctc atg cag ttg cgc aag 211 Ile Arg Leu Ala Glu Tyr Glu Met Pro Gly Leu Met Gln Leu Arg Lys 25 30 35 gaa ttc gca gac gag cag cct ttg aag ggc gcc cga att gct ggt tct 259 Glu Phe Ala Asp Glu Gln Pro Leu Lys Gly Ala Arg Ile Ala Gly Ser 40 45 50 atc cac atg acg gtc cag acc gcc gtg ctt att gag acc ctc act gct 307 Ile His Met Thr Val Gln Thr Ala Val Leu Ile Glu Thr Leu Thr Ala 55 60 65 ttg ggc gct gag gtt cgt tgg gct tcc tgc aac att ttc tcc acc cag 355 Leu Gly Ala Glu Val Arg Trp Ala Ser Cys Asn Ile Phe Ser Thr Gln 70 75 80 85 gat gag gct gca gcg gct atc gtt gtc ggc tcc ggc acc gtc gaa gag 403 Asp Glu Ala Ala Ala Ala Ile Val Val Gly Ser Gly Thr Val Glu Glu 90 95 100 cca gct ggt gtt cca gta ttc gcg tgg aag ggt gag tca ctg gag gag 451 Pro Ala Gly Val Pro Val Phe Ala Trp Lys Gly Glu Ser Leu Glu Glu 105 110 115 tac tgg tgg tgc atc aac cag atc ttc agc tgg ggc gat gag ctg cca 499 Tyr Trp Trp Cys Ile Asn Gln Ile Phe Ser Trp Gly Asp Glu Leu Pro 120 125 130 aac atg atc ctc gac gac ggc ggt gac gcc acc atg gct gtt att cgc 547 Asn Met Ile Leu Asp Asp Gly Gly Asp Ala Thr Met Ala Val Ile Arg 135 140 145 ggt cgc gaa tac gag cag gct ggt ctg gtt cca cca gca gag gcc aac 595 Gly Arg Glu Tyr Glu Gln Ala Gly Leu Val Pro Pro Ala Glu Ala Asn 150 155 160 165 gat tcc gat gag tac atc gca ttc ttg ggc atg ctg cgt gag gtt ctt 643 Asp Ser Asp Glu Tyr Ile Ala Phe Leu Gly Met Leu Arg Glu Val Leu 170 175 180 gct gca gag cct ggc aag tgg ggc aag atc gct gag gcc gtt aag ggt 691 Ala Ala Glu Pro Gly Lys Trp Gly Lys Ile Ala Glu Ala Val Lys Gly 185 190 195 gtc acc gag gaa acc acc acc ggt gtg cac cgc ctg tac cac ttc gct 739 Val Thr Glu Glu Thr Thr Thr Gly Val His Arg Leu Tyr His Phe Ala 200 205 210 gaa gaa ggc gtg ctg cct ttc cca gcg atg aac gtc aac gac gct gtc 787 Glu Glu Gly Val Leu Pro Phe Pro Ala Met Asn Val Asn Asp Ala Val 215 220 225 acc aag tcc aag ttt gat aac aag tac ggc acc cgc cac tcc ctg atc 835 Thr Lys Ser Lys Phe Asp Asn Lys Tyr Gly Thr Arg His Ser Leu Ile 230 235 240 245 gac ggc atc aac cgc gcc act gac atg ctc atg ggc ggc aag aac gtg 883 Asp Gly Ile Asn Arg Ala Thr Asp Met Leu Met Gly Gly Lys Asn Val 250 255 260 ctt gtc tgc ggt tac ggc gat gtc ggc aag ggc tgc gct gag gct ttc 931 Leu Val Cys Gly Tyr Gly Asp Val Gly Lys Gly Cys Ala Glu Ala Phe 265 270 275 gac ggc cag ggc gct cgc gtc aag gtc acc gaa gct gac cca atc aac 979 Asp Gly Gln Gly Ala Arg Val Lys Val Thr Glu Ala Asp Pro Ile Asn 280 285 290 gct ctt cag gct ctg atg gat ggc tac tct gtg gtc acc gtt gat gag 1027 Ala Leu Gln Ala Leu Met Asp Gly Tyr Ser Val Val Thr Val Asp Glu 295 300 305 gcc atc gag gac gcc gac atc gtg atc acc gcg acc ggc aac aag gac 1075 Ala Ile Glu Asp Ala Asp Ile Val Ile Thr Ala Thr Gly Asn Lys Asp 310 315 320 325 atc att tcc ttc gag cag atg ctc aag atg aag gat cac gct ctg ctg 1123 Ile Ile Ser Phe Glu Gln Met Leu Lys Met Lys Asp His Ala Leu Leu 330 335 340 ggc aac atc ggt cac ttt gat aat gag atc gat atg cat tcc ctg ttg 1171 Gly Asn Ile Gly His Phe Asp Asn Glu Ile Asp Met His Ser Leu Leu 345 350 355 cac cgc gac gac gtc acc cgc acc acg atc aag cca cag gtc gac gag 1219 His Arg Asp Asp Val Thr Arg Thr Thr Ile Lys Pro Gln Val Asp Glu 360 365 370 ttc acc ttc tcc acc ggt cgc tcc atc atc gtc ctg tcc gaa ggt cgc 1267 Phe Thr Phe Ser Thr Gly Arg Ser Ile Ile Val Leu Ser Glu Gly Arg 375 380 385 ctg ttg aac ctt ggc aac gcc acc gga cac cca tca ttt gtc atg tcc 1315 Leu Leu Asn Leu Gly Asn Ala Thr Gly His Pro Ser Phe Val Met Ser 390 395 400 405 aac tct ttc gcc gat cag acc att gcg cag atc gaa ctg ttc caa aac 1363 Asn Ser Phe Ala Asp Gln Thr Ile Ala Gln Ile Glu Leu Phe Gln Asn 410 415 420 gaa gga cag tac gag aac gag gtc tac cgt ctg cct aag gtt ctc gac 1411 Glu Gly Gln Tyr Glu Asn Glu Val Tyr Arg Leu Pro Lys Val Leu Asp 425 430 435 gaa aag gtg gca cgc atc cac gtt gag gct ctc ggc ggt cag ctc acc 1459 Glu Lys Val Ala Arg Ile His Val Glu Ala Leu Gly Gly Gln Leu Thr 440 445 450 gaa ctg acc aag gag cag gct gag tac atc ggc gtt gac gtt gca ggc 1507 Glu Leu Thr Lys Glu Gln Ala Glu Tyr Ile Gly Val Asp Val Ala Gly 455 460 465 cca ttc aag ccg gag cac tac cgc tac taatgattgt cagcattgag 1554 Pro Phe Lys Pro Glu His Tyr Arg Tyr 470 475 gga 1557 <210> 220 <211> 478 <212> PRT <213> Corynebacterium glutamicum <400> 220 Met Ala Gln Val Met Asp Phe Lys Val Ala Asp Leu Ser Leu Ala Glu 1 5 10 15 Ala Gly Arg His Gln Ile Arg Leu Ala Glu Tyr Glu Met Pro Gly Leu 20 25 30 Met Gln Leu Arg Lys Glu Phe Ala Asp Glu Gln Pro Leu Lys Gly Ala 35 40 45 Arg Ile Ala Gly Ser Ile His Met Thr Val Gln Thr Ala Val Leu Ile 50 55 60 Glu Thr Leu Thr Ala Leu Gly Ala Glu Val Arg Trp Ala Ser Cys Asn 65 70 75 80 Ile Phe Ser Thr Gln Asp Glu Ala Ala Ala Ala Ile Val Val Gly Ser 85 90 95 Gly Thr Val Glu Glu Pro Ala Gly Val Pro Val Phe Ala Trp Lys Gly 100 105 110 Glu Ser Leu Glu Glu Tyr Trp Trp Cys Ile Asn Gln Ile Phe Ser Trp 115 120 125 Gly Asp Glu Leu Pro Asn Met Ile Leu Asp Asp Gly Gly Asp Ala Thr 130 135 140 Met Ala Val Ile Arg Gly Arg Glu Tyr Glu Gln Ala Gly Leu Val Pro 145 150 155 160 Pro Ala Glu Ala Asn Asp Ser Asp Glu Tyr Ile Ala Phe Leu Gly Met 165 170 175 Leu Arg Glu Val Leu Ala Ala Glu Pro Gly Lys Trp Gly Lys Ile Ala 180 185 190 Glu Ala Val Lys Gly Val Thr Glu Glu Thr Thr Thr Gly Val His Arg 195 200 205 Leu Tyr His Phe Ala Glu Glu Gly Val Leu Pro Phe Pro Ala Met Asn 210 215 220 Val Asn Asp Ala Val Thr Lys Ser Lys Phe Asp Asn Lys Tyr Gly Thr 225 230 235 240 Arg His Ser Leu Ile Asp Gly Ile Asn Arg Ala Thr Asp Met Leu Met 245 250 255 Gly Gly Lys Asn Val Leu Val Cys Gly Tyr Gly Asp Val Gly Lys Gly 260 265 270 Cys Ala Glu Ala Phe Asp Gly Gln Gly Ala Arg Val Lys Val Thr Glu 275 280 285 Ala Asp Pro Ile Asn Ala Leu Gln Ala Leu Met Asp Gly Tyr Ser Val 290 295 300 Val Thr Val Asp Glu Ala Ile Glu Asp Ala Asp Ile Val Ile Thr Ala 305 310 315 320 Thr Gly Asn Lys Asp Ile Ile Ser Phe Glu Gln Met Leu Lys Met Lys 325 330 335 Asp His Ala Leu Leu Gly Asn Ile Gly His Phe Asp Asn Glu Ile Asp 340 345 350 Met His Ser Leu Leu His Arg Asp Asp Val Thr Arg Thr Thr Ile Lys 355 360 365 Pro Gln Val Asp Glu Phe Thr Phe Ser Thr Gly Arg Ser Ile Ile Val 370 375 380 Leu Ser Glu Gly Arg Leu Leu Asn Leu Gly Asn Ala Thr Gly His Pro 385 390 395 400 Ser Phe Val Met Ser Asn Ser Phe Ala Asp Gln Thr Ile Ala Gln Ile 405 410 415 Glu Leu Phe Gln Asn Glu Gly Gln Tyr Glu Asn Glu Val Tyr Arg Leu 420 425 430 Pro Lys Val Leu Asp Glu Lys Val Ala Arg Ile His Val Glu Ala Leu 435 440 445 Gly Gly Gln Leu Thr Glu Leu Thr Lys Glu Gln Ala Glu Tyr Ile Gly 450 455 460 Val Asp Val Ala Gly Pro Phe Lys Pro Glu His Tyr Arg Tyr 465 470 475 <210> 221 <211> 128 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(105) <223> FRXA00132 <400> 221 cac gtt gag gct ctc ggc ggt cag ctc acc gaa ctg acc aag gag cag 48 His Val Glu Ala Leu Gly Gly Gln Leu Thr Glu Leu Thr Lys Glu Gln 1 5 10 15 gct gag tac atc ggc gtt gac gtt gca ggc cca ttc aag ccg gag cac 96 Ala Glu Tyr Ile Gly Val Asp Val Ala Gly Pro Phe Lys Pro Glu His 20 25 30 tac cgc tac taatgattgt cagcattgag gga 128 Tyr Arg Tyr 35 <210> 222 <211> 35 <212> PRT <213> Corynebacterium glutamicum <400> 222 His Val Glu Ala Leu Gly Gly Gln Leu Thr Glu Leu Thr Lys Glu Gln 1 5 10 15 Ala Glu Tyr Ile Gly Val Asp Val Ala Gly Pro Phe Lys Pro Glu His 20 25 30 Tyr Arg Tyr 35 <210> 223 <211> 1396 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1396) <223> FRXA01371 <400> 223 aacagcttca atcaattcgg tgtccactcc aacatgtaga gtggtgcgcg ttaaaaaagt 60 tttcctaatt ttcattttct taaaaggagc tcgccaggac atg gca cag gtt atg 115 Met Ala Gln Val Met 1 5 gac ttc aag gtt gcc gat ctt tca cta gca gag gca gga cgt cac cag 163 Asp Phe Lys Val Ala Asp Leu Ser Leu Ala Glu Ala Gly Arg His Gln 10 15 20 att cgt ctt gca gag tat gag atg cca ggt ctc atg cag ttg cgc aag 211 Ile Arg Leu Ala Glu Tyr Glu Met Pro Gly Leu Met Gln Leu Arg Lys 25 30 35 gaa ttc gca gac gag cag cct ttg aag ggc gcc cga att gct ggt tct 259 Glu Phe Ala Asp Glu Gln Pro Leu Lys Gly Ala Arg Ile Ala Gly Ser 40 45 50 atc cac atg acg gtc cag acc gcc gtg ctt att gag acc ctc act gct 307 Ile His Met Thr Val Gln Thr Ala Val Leu Ile Glu Thr Leu Thr Ala 55 60 65 ttg ggc gct gag gtt cgt tgg gct tcc tgc aac att ttc tcc acc cag 355 Leu Gly Ala Glu Val Arg Trp Ala Ser Cys Asn Ile Phe Ser Thr Gln 70 75 80 85 gat gag gct gca gcg gct atc gtt gtc ggc tcc ggc acc gtc gaa gag 403 Asp Glu Ala Ala Ala Ala Ile Val Val Gly Ser Gly Thr Val Glu Glu 90 95 100 cca gct ggt gtt cca gta ttc gcg tgg aag ggt gag tca ctg gag gag 451 Pro Ala Gly Val Pro Val Phe Ala Trp Lys Gly Glu Ser Leu Glu Glu 105 110 115 tac tgg tgg tgc atc aac cag atc ttc agc tgg ggc gat gag ctg cca 499 Tyr Trp Trp Cys Ile Asn Gln Ile Phe Ser Trp Gly Asp Glu Leu Pro 120 125 130 aac atg atc ctc gac gac ggc ggt gac gcc acc atg gct gtt att cgc 547 Asn Met Ile Leu Asp Asp Gly Gly Asp Ala Thr Met Ala Val Ile Arg 135 140 145 ggt cgc gaa tac gag cag gct ggt ctg gtt cca cca gca gag gcc aac 595 Gly Arg Glu Tyr Glu Gln Ala Gly Leu Val Pro Pro Ala Glu Ala Asn 150 155 160 165 gat tcc gat gag tac atc gca ttc ttg ggc atg ctg cgt gag gtt ctt 643 Asp Ser Asp Glu Tyr Ile Ala Phe Leu Gly Met Leu Arg Glu Val Leu 170 175 180 gct gca gag cct ggc aag tgg ggc aag atc gct gag gcc gtt aag ggt 691 Ala Ala Glu Pro Gly Lys Trp Gly Lys Ile Ala Glu Ala Val Lys Gly 185 190 195 gtc acc gag gaa acc acc acc ggt gtg cac cgc ctg tac cac ttc gct 739 Val Thr Glu Glu Thr Thr Thr Gly Val His Arg Leu Tyr His Phe Ala 200 205 210 gaa gaa ggc gtg ctg cct ttc cca gcg atg aac gtc aac gac gct gtc 787 Glu Glu Gly Val Leu Pro Phe Pro Ala Met Asn Val Asn Asp Ala Val 215 220 225 acc aag tcc aag ttt gat aac aag tac ggc acc cgc cac tcc ctg atc 835 Thr Lys Ser Lys Phe Asp Asn Lys Tyr Gly Thr Arg His Ser Leu Ile 230 235 240 245 gac ggc atc aac cgc gcc act gac atg ctc atg ggc ggc aag aac gtg 883 Asp Gly Ile Asn Arg Ala Thr Asp Met Leu Met Gly Gly Lys Asn Val 250 255 260 ctt gtc tgc ggt tac ggc gat gtc ggc aag ggc tgc gct gag gct ttc 931 Leu Val Cys Gly Tyr Gly Asp Val Gly Lys Gly Cys Ala Glu Ala Phe 265 270 275 gac ggc cag ggc gct cgc gtc aag gtc acc gaa gct gac cca atc aac 979 Asp Gly Gln Gly Ala Arg Val Lys Val Thr Glu Ala Asp Pro Ile Asn 280 285 290 gct ctt cag gct ctg atg gat ggc tac tct gtg gtc acc gtt gat gag 1027 Ala Leu Gln Ala Leu Met Asp Gly Tyr Ser Val Val Thr Val Asp Glu 295 300 305 gcc atc gag gac gcc gac atc gtg atc acc gcg acc ggc aac aag gac 1075 Ala Ile Glu Asp Ala Asp Ile Val Ile Thr Ala Thr Gly Asn Lys Asp 310 315 320 325 atc att tcc ttc gag cag atg ctc aag atg aag gat cac gct ctg ctg 1123 Ile Ile Ser Phe Glu Gln Met Leu Lys Met Lys Asp His Ala Leu Leu 330 335 340 ggc aac atc ggt cac ttt gat aat gag atc gat atg cat tcc ctg ttg 1171 Gly Asn Ile Gly His Phe Asp Asn Glu Ile Asp Met His Ser Leu Leu 345 350 355 cac cgc gac gac gtc acc cgc acc acg atc aag cca cag gtc gac gag 1219 His Arg Asp Asp Val Thr Arg Thr Thr Ile Lys Pro Gln Val Asp Glu 360 365 370 ttc acc ttc tcc acc ggt cgc tcc atc atc gtc ctg tcc gaa ggt cgc 1267 Phe Thr Phe Ser Thr Gly Arg Ser Ile Ile Val Leu Ser Glu Gly Arg 375 380 385 ctg ttg aac ctt ggc aac gcc acc gga cac cca tca ttt gtc atg tcc 1315 Leu Leu Asn Leu Gly Asn Ala Thr Gly His Pro Ser Phe Val Met Ser 390 395 400 405 aac tct ttc gcc gat cag acc att gcg cag atc gaa ctg ttc caa aac 1363 Asn Ser Phe Ala Asp Gln Thr Ile Ala Gln Ile Glu Leu Phe Gln Asn 410 415 420 gaa gga cag tac gag aac gag gtc tac cgt ctg 1396 Glu Gly Gln Tyr Glu Asn Glu Val Tyr Arg Leu 425 430 <210> 224 <211> 432 <212> PRT <213> Corynebacterium glutamicum <400> 224 Met Ala Gln Val Met Asp Phe Lys Val Ala Asp Leu Ser Leu Ala Glu 1 5 10 15 Ala Gly Arg His Gln Ile Arg Leu Ala Glu Tyr Glu Met Pro Gly Leu 20 25 30 Met Gln Leu Arg Lys Glu Phe Ala Asp Glu Gln Pro Leu Lys Gly Ala 35 40 45 Arg Ile Ala Gly Ser Ile His Met Thr Val Gln Thr Ala Val Leu Ile 50 55 60 Glu Thr Leu Thr Ala Leu Gly Ala Glu Val Arg Trp Ala Ser Cys Asn 65 70 75 80 Ile Phe Ser Thr Gln Asp Glu Ala Ala Ala Ala Ile Val Val Gly Ser 85 90 95 Gly Thr Val Glu Glu Pro Ala Gly Val Pro Val Phe Ala Trp Lys Gly 100 105 110 Glu Ser Leu Glu Glu Tyr Trp Trp Cys Ile Asn Gln Ile Phe Ser Trp 115 120 125 Gly Asp Glu Leu Pro Asn Met Ile Leu Asp Asp Gly Gly Asp Ala Thr 130 135 140 Met Ala Val Ile Arg Gly Arg Glu Tyr Glu Gln Ala Gly Leu Val Pro 145 150 155 160 Pro Ala Glu Ala Asn Asp Ser Asp Glu Tyr Ile Ala Phe Leu Gly Met 165 170 175 Leu Arg Glu Val Leu Ala Ala Glu Pro Gly Lys Trp Gly Lys Ile Ala 180 185 190 Glu Ala Val Lys Gly Val Thr Glu Glu Thr Thr Thr Gly Val His Arg 195 200 205 Leu Tyr His Phe Ala Glu Glu Gly Val Leu Pro Phe Pro Ala Met Asn 210 215 220 Val Asn Asp Ala Val Thr Lys Ser Lys Phe Asp Asn Lys Tyr Gly Thr 225 230 235 240 Arg His Ser Leu Ile Asp Gly Ile Asn Arg Ala Thr Asp Met Leu Met 245 250 255 Gly Gly Lys Asn Val Leu Val Cys Gly Tyr Gly Asp Val Gly Lys Gly 260 265 270 Cys Ala Glu Ala Phe Asp Gly Gln Gly Ala Arg Val Lys Val Thr Glu 275 280 285 Ala Asp Pro Ile Asn Ala Leu Gln Ala Leu Met Asp Gly Tyr Ser Val 290 295 300 Val Thr Val Asp Glu Ala Ile Glu Asp Ala Asp Ile Val Ile Thr Ala 305 310 315 320 Thr Gly Asn Lys Asp Ile Ile Ser Phe Glu Gln Met Leu Lys Met Lys 325 330 335 Asp His Ala Leu Leu Gly Asn Ile Gly His Phe Asp Asn Glu Ile Asp 340 345 350 Met His Ser Leu Leu His Arg Asp Asp Val Thr Arg Thr Thr Ile Lys 355 360 365 Pro Gln Val Asp Glu Phe Thr Phe Ser Thr Gly Arg Ser Ile Ile Val 370 375 380 Leu Ser Glu Gly Arg Leu Leu Asn Leu Gly Asn Ala Thr Gly His Pro 385 390 395 400 Ser Phe Val Met Ser Asn Ser Phe Ala Asp Gln Thr Ile Ala Gln Ile 405 410 415 Glu Leu Phe Gln Asn Glu Gly Gln Tyr Glu Asn Glu Val Tyr Arg Leu 420 425 430 <210> 225 <211> 2358 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2335) <223> RXN02085 <400> 225 cacccggtga tttcgcgaac cttgaaacat cgtcagaaga ttgccgtgcg tcctagccgg 60 gatccgcacg ttcggctcaa gcagaaagtc tttaactcac atg act tcc aac ttt 115 Met Thr Ser Asn Phe 1 5 tct tcc act gtc gct ggt ctt cct cgc atc gga gcg aag cgt gaa ctg 163 Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly Ala Lys Arg Glu Leu 10 15 20 aag ttc gcg ctc gaa ggc tac tgg aat gga tca att gaa ggt cgc gaa 211 Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser Ile Glu Gly Arg Glu 25 30 35 ctt gcg cag acc gcc cgc caa ttg gtc aac act gca tcg gat tct ttg 259 Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr Ala Ser Asp Ser Leu 40 45 50 tct gga ttg gat tcc gtt ccg ttt gca gga cgt tcc tac tac gac gca 307 Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg Ser Tyr Tyr Asp Ala 55 60 65 atg ctc gat acc gcc gct att ttg ggt gtg ctg ccg gag cgt ttt gat 355 Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu Pro Glu Arg Phe Asp 70 75 80 85 gac atc gct gat cat gaa aac gat ggt ctc cca ctg tgg att gac cgc 403 Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro Leu Trp Ile Asp Arg 90 95 100 tac ttt ggc gct gct cgc ggt act gag acc ctg cct gca cag gca atg 451 Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu Pro Ala Gln Ala Met 105 110 115 acc aag tgg ttt gat acc aac tac cac tac ctc gtg ccg gag ttg tct 499 Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu Val Pro Glu Leu Ser 120 125 130 gcg gat aca cgt ttc gtt ttg gat gcg tcc gcg ctg att gag gat ctc 547 Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala Leu Ile Glu Asp Leu 135 140 145 cgt tgc cag cag gtt cgt ggc gtt aat gcc cgc cct gtt ctg gtt ggt 595 Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg Pro Val Leu Val Gly 150 155 160 165 cca ctg act ttc ctt tcc ctt gct cgc acc act gat ggt tcc aat cct 643 Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr Asp Gly Ser Asn Pro 170 175 180 ttg gat cac ctg cct gca ctg ttt gag gtc tac gag cgc ctc atc aag 691 Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr Glu Arg Leu Ile Lys 185 190 195 tct ttc gat act gag tgg gtt cag atc gat gag cct gcg ttg gtc acc 739 Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu Pro Ala Leu Val Thr 200 205 210 gat gtt gct cct gag gtt ttg gag cag gtc cgc gct ggt tac acc act 787 Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg Ala Gly Tyr Thr Thr 215 220 225 ttg gct aag cgc gat ggc gtg ttt gtc aat act tac ttc ggc tct ggc 835 Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr Tyr Phe Gly Ser Gly 230 235 240 245 gat cag gcg ctg aac act ctt gcg ggc atc ggc ctt ggc gcg att ggc 883 Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly Leu Gly Ala Ile Gly 250 255 260 gtt gac ttg gtc acc cat ggc gtc act gag ctt gct gcg tgg aag ggt 931 Val Asp Leu Val Thr His Gly Val Thr Glu Leu Ala Ala Trp Lys Gly 265 270 275 gag gag ctg ctg gtt gcg ggc atc gtt gat ggt cgt aac att tgg cgc 979 Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly Arg Asn Ile Trp Arg 280 285 290 acc gac ctg tgt gct gct ctt gct tcc ctg aag cgc ctg gca gct cgc 1027 Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys Arg Leu Ala Ala Arg 295 300 305 ggc cca atc gca gtg tct acc tct tgt tca ctg ctg cac gtt cct tac 1075 Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu Leu His Val Pro Tyr 310 315 320 325 acc ctc gag gct gag aac att gag cct gag gtc cgc gac tgg ctt gcc 1123 Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val Arg Asp Trp Leu Ala 330 335 340 ttc ggc tcg gag aag atc acc gag gtc aag ctg ctt gcc gac gcc cta 1171 Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu Leu Ala Asp Ala Leu 345 350 355 gcc ggc aac atc gac gcg gct gcg ttc gat gcg gcg tcc gca gca att 1219 Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala Ala Ser Ala Ala Ile 360 365 370 gct tct cga cgc acc tcc cca cgc acc gca cca atc acg cag gaa ctc 1267 Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro Ile Thr Gln Glu Leu 375 380 385 cct ggc cgt agc cgt gga tcc ttc gac act cgt gtt acg ctg cag gag 1315 Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg Val Thr Leu Gln Glu 390 395 400 405 aag tca ctg gag ctt cca gct ctg cca acc acc acc att ggt tct ttc 1363 Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr Thr Ile Gly Ser Phe 410 415 420 cca cag acc cca tcc att cgt tct gct cgc gct cgt ctg cgc aag gaa 1411 Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala Arg Leu Arg Lys Glu 425 430 435 tcc atc act ttg gag cag tac gaa gag gca atg cgc gaa gaa atc gat 1459 Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met Arg Glu Glu Ile Asp 440 445 450 ctg gtc atc gcc aag cag gaa gaa ctt ggt ctt gat gtg ttg gtt cac 1507 Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu Asp Val Leu Val His 455 460 465 ggt gag cca gag cgc aac gac atg gtt cag tac ttc tct gaa ctt ctc 1555 Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr Phe Ser Glu Leu Leu 470 475 480 485 gac ggt ttc ctc tca acc gcc aac ggc tgg gtc caa agc tac ggc tcc 1603 Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val Gln Ser Tyr Gly Ser 490 495 500 cgc tgt gtt cgt cct cca gtg ttg ttc gga aac gtt tcc cgc cca gcg 1651 Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn Val Ser Arg Pro Ala 505 510 515 cca atg act gtc aag tgg ttc cag tac gca cag agc ctg acc cag aag 1699 Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln Ser Leu Thr Gln Lys 520 525 530 cat gtc aag gga atg ctc acc ggt cca gtc acc atc ctt gca tgg tcc 1747 His Val Lys Gly Met Leu Thr Gly Pro Val Thr Ile Leu Ala Trp Ser 535 540 545 ttc gtt cgc gat gat cag ccg ctg gct acc act gct gac cag gtt gca 1795 Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr Ala Asp Gln Val Ala 550 555 560 565 ctg gca ctg cgc gat gaa att aac gat ctc atc gag gct ggc gcg aag 1843 Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile Glu Ala Gly Ala Lys 570 575 580 atc atc cag gtg gat gag cct gcg att cgt gaa ctg ttg ccg cta cga 1891 Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu Leu Leu Pro Leu Arg 585 590 595 gac gtc gat aag cct gcc tac ctg cag tgg tcc gtg gac tcc ttc cgc 1939 Asp Val Asp Lys Pro Ala Tyr Leu Gln Trp Ser Val Asp Ser Phe Arg 600 605 610 ctg gcg act gcc ggc gca ccc gac gac gtc caa atc cac acc cac atg 1987 Leu Ala Thr Ala Gly Ala Pro Asp Asp Val Gln Ile His Thr His Met 615 620 625 tgc tac tcc gag ttc aac gaa gtg atc tcc tcg gtc atc gcg ttg gat 2035 Cys Tyr Ser Glu Phe Asn Glu Val Ile Ser Ser Val Ile Ala Leu Asp 630 635 640 645 gcc gat gtc acc acc atc gaa gca gca cgt tcc gac atg cag gtc ctc 2083 Ala Asp Val Thr Thr Ile Glu Ala Ala Arg Ser Asp Met Gln Val Leu 650 655 660 gct gct ctg aaa tct tcc ggc ttc gag ctc ggc gtc gga cct ggt gtg 2131 Ala Ala Leu Lys Ser Ser Gly Phe Glu Leu Gly Val Gly Pro Gly Val 665 670 675 tgg gat atc cac tcc ccg cgc gtt cct tcc gcg cag aaa gtg gac ggt 2179 Trp Asp Ile His Ser Pro Arg Val Pro Ser Ala Gln Lys Val Asp Gly 680 685 690 ctc ctc gag gct gca ctg cag tcc gtg gat cct cgc cag ctg tgg gtc 2227 Leu Leu Glu Ala Ala Leu Gln Ser Val Asp Pro Arg Gln Leu Trp Val 695 700 705 aac cca gac tgt ggt ctg aag acc cgt gga tgg cca gaa gtg gaa gct 2275 Asn Pro Asp Cys Gly Leu Lys Thr Arg Gly Trp Pro Glu Val Glu Ala 710 715 720 725 tcc cta aag gtt ctc gtt gag tcc gct aag cag gct cgt gag aaa atc 2323 Ser Leu Lys Val Leu Val Glu Ser Ala Lys Gln Ala Arg Glu Lys Ile 730 735 740 gga gca act atc taaattgggt taccgctagg aac 2358 Gly Ala Thr Ile 745 <210> 226 <211> 745 <212> PRT <213> Corynebacterium glutamicum <400> 226 Met Thr Ser Asn Phe Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly 1 5 10 15 Ala Lys Arg Glu Leu Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser 20 25 30 Ile Glu Gly Arg Glu Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr 35 40 45 Ala Ser Asp Ser Leu Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg 50 55 60 Ser Tyr Tyr Asp Ala Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu 65 70 75 80 Pro Glu Arg Phe Asp Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro 85 90 95 Leu Trp Ile Asp Arg Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu 100 105 110 Pro Ala Gln Ala Met Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu 115 120 125 Val Pro Glu Leu Ser Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala 130 135 140 Leu Ile Glu Asp Leu Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg 145 150 155 160 Pro Val Leu Val Gly Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr 165 170 175 Asp Gly Ser Asn Pro Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr 180 185 190 Glu Arg Leu Ile Lys Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu 195 200 205 Pro Ala Leu Val Thr Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg 210 215 220 Ala Gly Tyr Thr Thr Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr 225 230 235 240 Tyr Phe Gly Ser Gly Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly 245 250 255 Leu Gly Ala Ile Gly Val Asp Leu Val Thr His Gly Val Thr Glu Leu 260 265 270 Ala Ala Trp Lys Gly Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly 275 280 285 Arg Asn Ile Trp Arg Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys 290 295 300 Arg Leu Ala Ala Arg Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu 305 310 315 320 Leu His Val Pro Tyr Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val 325 330 335 Arg Asp Trp Leu Ala Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu 340 345 350 Leu Ala Asp Ala Leu Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala 355 360 365 Ala Ser Ala Ala Ile Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro 370 375 380 Ile Thr Gln Glu Leu Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg 385 390 395 400 Val Thr Leu Gln Glu Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr 405 410 415 Thr Ile Gly Ser Phe Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala 420 425 430 Arg Leu Arg Lys Glu Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met 435 440 445 Arg Glu Glu Ile Asp Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu 450 455 460 Asp Val Leu Val His Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr 465 470 475 480 Phe Ser Glu Leu Leu Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val 485 490 495 Gln Ser Tyr Gly Ser Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn 500 505 510 Val Ser Arg Pro Ala Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln 515 520 525 Ser Leu Thr Gln Lys His Val Lys Gly Met Leu Thr Gly Pro Val Thr 530 535 540 Ile Leu Ala Trp Ser Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr 545 550 555 560 Ala Asp Gln Val Ala Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile 565 570 575 Glu Ala Gly Ala Lys Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu 580 585 590 Leu Leu Pro Leu Arg Asp Val Asp Lys Pro Ala Tyr Leu Gln Trp Ser 595 600 605 Val Asp Ser Phe Arg Leu Ala Thr Ala Gly Ala Pro Asp Asp Val Gln 610 615 620 Ile His Thr His Met Cys Tyr Ser Glu Phe Asn Glu Val Ile Ser Ser 625 630 635 640 Val Ile Ala Leu Asp Ala Asp Val Thr Thr Ile Glu Ala Ala Arg Ser 645 650 655 Asp Met Gln Val Leu Ala Ala Leu Lys Ser Ser Gly Phe Glu Leu Gly 660 665 670 Val Gly Pro Gly Val Trp Asp Ile His Ser Pro Arg Val Pro Ser Ala 675 680 685 Gln Lys Val Asp Gly Leu Leu Glu Ala Ala Leu Gln Ser Val Asp Pro 690 695 700 Arg Gln Leu Trp Val Asn Pro Asp Cys Gly Leu Lys Thr Arg Gly Trp 705 710 715 720 Pro Glu Val Glu Ala Ser Leu Lys Val Leu Val Glu Ser Ala Lys Gln 725 730 735 Ala Arg Glu Lys Ile Gly Ala Thr Ile 740 745 <210> 227 <211> 1923 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1900) <223> FRXA02085 <400> 227 cacccggtga tttcgcgaac cttgaaacat cgtcagaaga ttgccgtgcg tcctagccgg 60 gatccgcacg ttcggctcaa gcagaaagtc tttaactcac atg act tcc aac ttt 115 Met Thr Ser Asn Phe 1 5 tct tcc act gtc gct ggt ctt cct cgc atc gga gcg aag cgt gaa ctg 163 Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly Ala Lys Arg Glu Leu 10 15 20 aag ttc gcg ctc gaa ggc tac tgg aat gga tca att gaa ggt cgc gaa 211 Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser Ile Glu Gly Arg Glu 25 30 35 ctt gcg cag acc gcc cgc caa ttg gtc aac act gca tcg gat tct ttg 259 Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr Ala Ser Asp Ser Leu 40 45 50 tct gga ttg gat tcc gtt ccg ttt gca gga cgt tcc tac tac gac gca 307 Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg Ser Tyr Tyr Asp Ala 55 60 65 atg ctc gat acc gcc gct att ttg ggt gtg ctg ccg gag cgt ttt gat 355 Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu Pro Glu Arg Phe Asp 70 75 80 85 gac atc gct gat cat gaa aac gat ggt ctc cca ctg tgg att gac cgc 403 Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro Leu Trp Ile Asp Arg 90 95 100 tac ttt ggc gct gct cgc ggt act gag acc ctg cct gca cag gca atg 451 Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu Pro Ala Gln Ala Met 105 110 115 acc aag tgg ttt gat acc aac tac cac tac ctc gtg ccg gag ttg tct 499 Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu Val Pro Glu Leu Ser 120 125 130 gcg gat aca cgt ttc gtt ttg gat gcg tcc gcg ctg att gag gat ctc 547 Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala Leu Ile Glu Asp Leu 135 140 145 cgt tgc cag cag gtt cgt ggc gtt aat gcc cgc cct gtt ctg gtt ggt 595 Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg Pro Val Leu Val Gly 150 155 160 165 cca ctg act ttc ctt tcc ctt gct cgc acc act gat ggt tcc aat cct 643 Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr Asp Gly Ser Asn Pro 170 175 180 ttg gat cac ctg cct gca ctg ttt gag gtc tac gag cgc ctc atc aag 691 Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr Glu Arg Leu Ile Lys 185 190 195 tct ttc gat act gag tgg gtt cag atc gat gag cct gcg ttg gtc acc 739 Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu Pro Ala Leu Val Thr 200 205 210 gat gtt gct cct gag gtt ttg gag cag gtc cgc gct ggt tac acc act 787 Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg Ala Gly Tyr Thr Thr 215 220 225 ttg gct aag cgc gat ggc gtg ttt gtc aat act tac ttc ggc tct ggc 835 Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr Tyr Phe Gly Ser Gly 230 235 240 245 gat cag gcg ctg aac act ctt gcg ggc atc ggc ctt ggc gcg att ggc 883 Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly Leu Gly Ala Ile Gly 250 255 260 gtt gac ttg gtc acc cat ggc gtc act gag ctt gct gcg tgg aag ggt 931 Val Asp Leu Val Thr His Gly Val Thr Glu Leu Ala Ala Trp Lys Gly 265 270 275 gag gag ctg ctg gtt gcg ggc atc gtt gat ggt cgt aac att tgg cgc 979 Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly Arg Asn Ile Trp Arg 280 285 290 acc gac ctg tgt gct gct ctt gct tcc ctg aag cgc ctg gca gct cgc 1027 Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys Arg Leu Ala Ala Arg 295 300 305 ggc cca atc gca gtg tct acc tct tgt tca ctg ctg cac gtt cct tac 1075 Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu Leu His Val Pro Tyr 310 315 320 325 acc ctc gag gct gag aac att gag cct gag gtc cgc gac tgg ctt gcc 1123 Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val Arg Asp Trp Leu Ala 330 335 340 ttc ggc tcg gag aag atc acc gag gtc aag ctg ctt gcc gac gcc cta 1171 Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu Leu Ala Asp Ala Leu 345 350 355 gcc ggc aac atc gac gcg gct gcg ttc gat gcg gcg tcc gca gca att 1219 Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala Ala Ser Ala Ala Ile 360 365 370 gct tct cga cgc acc tcc cca cgc acc gca cca atc acg cag gaa ctc 1267 Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro Ile Thr Gln Glu Leu 375 380 385 cct ggc cgt agc cgt gga tcc ttc gac act cgt gtt acg ctg cag gag 1315 Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg Val Thr Leu Gln Glu 390 395 400 405 aag tca ctg gag ctt cca gct ctg cca acc acc acc att ggt tct ttc 1363 Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr Thr Ile Gly Ser Phe 410 415 420 cca cag acc cca tcc att cgt tct gct cgc gct cgt ctg cgc aag gaa 1411 Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala Arg Leu Arg Lys Glu 425 430 435 tcc atc act ttg gag cag tac gaa gag gca atg cgc gaa gaa atc gat 1459 Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met Arg Glu Glu Ile Asp 440 445 450 ctg gtc atc gcc aag cag gaa gaa ctt ggt ctt gat gtg ttg gtt cac 1507 Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu Asp Val Leu Val His 455 460 465 ggt gag cca gag cgc aac gac atg gtt cag tac ttc tct gaa ctt ctc 1555 Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr Phe Ser Glu Leu Leu 470 475 480 485 gac ggt ttc ctc tca acc gcc aac ggc tgg gtc caa agc tac ggc tcc 1603 Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val Gln Ser Tyr Gly Ser 490 495 500 cgc tgt gtt cgt cct cca gtg ttg ttc gga aac gtt tcc cgc cca gcg 1651 Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn Val Ser Arg Pro Ala 505 510 515 cca atg act gtc aag tgg ttc cag tac gca cag agc ctg acc cag aag 1699 Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln Ser Leu Thr Gln Lys 520 525 530 cat gtc aag gga atg ctc acc ggt cca gtc acc atc ctt gca tgg tcc 1747 His Val Lys Gly Met Leu Thr Gly Pro Val Thr Ile Leu Ala Trp Ser 535 540 545 ttc gtt cgc gat gat cag ccg ctg gct acc act gct gac cag gtt gca 1795 Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr Ala Asp Gln Val Ala 550 555 560 565 ctg gca ctg cgc gat gaa att aac gat ctc atc gag gct ggc gcg aag 1843 Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile Glu Ala Gly Ala Lys 570 575 580 atc atc cag gtg gat gag cct gcg att cgt gaa ctg ttg ccc gct acg 1891 Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu Leu Leu Pro Ala Thr 585 590 595 aga cgt cga taagcctgcc tacctgcagt ggt 1923 Arg Arg Arg 600 <210> 228 <211> 600 <212> PRT <213> Corynebacterium glutamicum <400> 228 Met Thr Ser Asn Phe Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly 1 5 10 15 Ala Lys Arg Glu Leu Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser 20 25 30 Ile Glu Gly Arg Glu Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr 35 40 45 Ala Ser Asp Ser Leu Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg 50 55 60 Ser Tyr Tyr Asp Ala Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu 65 70 75 80 Pro Glu Arg Phe Asp Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro 85 90 95 Leu Trp Ile Asp Arg Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu 100 105 110 Pro Ala Gln Ala Met Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu 115 120 125 Val Pro Glu Leu Ser Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala 130 135 140 Leu Ile Glu Asp Leu Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg 145 150 155 160 Pro Val Leu Val Gly Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr 165 170 175 Asp Gly Ser Asn Pro Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr 180 185 190 Glu Arg Leu Ile Lys Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu 195 200 205 Pro Ala Leu Val Thr Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg 210 215 220 Ala Gly Tyr Thr Thr Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr 225 230 235 240 Tyr Phe Gly Ser Gly Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly 245 250 255 Leu Gly Ala Ile Gly Val Asp Leu Val Thr His Gly Val Thr Glu Leu 260 265 270 Ala Ala Trp Lys Gly Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly 275 280 285 Arg Asn Ile Trp Arg Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys 290 295 300 Arg Leu Ala Ala Arg Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu 305 310 315 320 Leu His Val Pro Tyr Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val 325 330 335 Arg Asp Trp Leu Ala Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu 340 345 350 Leu Ala Asp Ala Leu Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala 355 360 365 Ala Ser Ala Ala Ile Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro 370 375 380 Ile Thr Gln Glu Leu Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg 385 390 395 400 Val Thr Leu Gln Glu Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr 405 410 415 Thr Ile Gly Ser Phe Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala 420 425 430 Arg Leu Arg Lys Glu Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met 435 440 445 Arg Glu Glu Ile Asp Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu 450 455 460 Asp Val Leu Val His Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr 465 470 475 480 Phe Ser Glu Leu Leu Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val 485 490 495 Gln Ser Tyr Gly Ser Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn 500 505 510 Val Ser Arg Pro Ala Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln 515 520 525 Ser Leu Thr Gln Lys His Val Lys Gly Met Leu Thr Gly Pro Val Thr 530 535 540 Ile Leu Ala Trp Ser Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr 545 550 555 560 Ala Asp Gln Val Ala Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile 565 570 575 Glu Ala Gly Ala Lys Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu 580 585 590 Leu Leu Pro Ala Thr Arg Arg Arg 595 600 <210> 229 <211> 603 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(580) <223> FRXA02086 <400> 229 gatgatcagc cgctggctac cactgctgac caggttgcac tggcactgcg cgatgaaatt 60 aacgatctca tcgaggctgg cgcgaagatc atccaggtgg atg agc ctg cga ttc 115 Met Ser Leu Arg Phe 1 5 gtg aac tgt tgc ccg cta cga gac gtc gat aag cct gcc tac ctg cag 163 Val Asn Cys Cys Pro Leu Arg Asp Val Asp Lys Pro Ala Tyr Leu Gln 10 15 20 tgg tcc gtg gac tcc ttc cgc ctg gcg act gcc ggc gca ccc gac gac 211 Trp Ser Val Asp Ser Phe Arg Leu Ala Thr Ala Gly Ala Pro Asp Asp 25 30 35 gtc caa atc cac acc cac atg tgc tac tcc gag ttc aac gaa gtg atc 259 Val Gln Ile His Thr His Met Cys Tyr Ser Glu Phe Asn Glu Val Ile 40 45 50 tcc tcg gtc atc gcg ttg gat gcc gat gtc acc acc atc gaa gca gca 307 Ser Ser Val Ile Ala Leu Asp Ala Asp Val Thr Thr Ile Glu Ala Ala 55 60 65 cgt tcc gac atg cag gtc ctc gct gct ctg aaa tct tcc ggc ttc gag 355 Arg Ser Asp Met Gln Val Leu Ala Ala Leu Lys Ser Ser Gly Phe Glu 70 75 80 85 ctc ggc gtc gga cct ggt gtg tgg gat atc cac tcc ccg cgc gtt cct 403 Leu Gly Val Gly Pro Gly Val Trp Asp Ile His Ser Pro Arg Val Pro 90 95 100 tcc gcg cag aaa gtg gac ggt ctc ctc gag gct gca ctg cag tcc gtg 451 Ser Ala Gln Lys Val Asp Gly Leu Leu Glu Ala Ala Leu Gln Ser Val 105 110 115 gat cct cgc cag ctg tgg gtc aac cca gac tgt ggt ctg aag acc cgt 499 Asp Pro Arg Gln Leu Trp Val Asn Pro Asp Cys Gly Leu Lys Thr Arg 120 125 130 gga tgg cca gaa gtg gaa gct tcc cta aag gtt ctc gtt gag tcc gct 547 Gly Trp Pro Glu Val Glu Ala Ser Leu Lys Val Leu Val Glu Ser Ala 135 140 145 aag cag gct cgt gag aaa atc gga gca act atc taaattgggt taccgctagg 600 Lys Gln Ala Arg Glu Lys Ile Gly Ala Thr Ile 150 155 160 aac 603 <210> 230 <211> 160 <212> PRT <213> Corynebacterium glutamicum <400> 230 Met Ser Leu Arg Phe Val Asn Cys Cys Pro Leu Arg Asp Val Asp Lys 1 5 10 15 Pro Ala Tyr Leu Gln Trp Ser Val Asp Ser Phe Arg Leu Ala Thr Ala 20 25 30 Gly Ala Pro Asp Asp Val Gln Ile His Thr His Met Cys Tyr Ser Glu 35 40 45 Phe Asn Glu Val Ile Ser Ser Val Ile Ala Leu Asp Ala Asp Val Thr 50 55 60 Thr Ile Glu Ala Ala Arg Ser Asp Met Gln Val Leu Ala Ala Leu Lys 65 70 75 80 Ser Ser Gly Phe Glu Leu Gly Val Gly Pro Gly Val Trp Asp Ile His 85 90 95 Ser Pro Arg Val Pro Ser Ala Gln Lys Val Asp Gly Leu Leu Glu Ala 100 105 110 Ala Leu Gln Ser Val Asp Pro Arg Gln Leu Trp Val Asn Pro Asp Cys 115 120 125 Gly Leu Lys Thr Arg Gly Trp Pro Glu Val Glu Ala Ser Leu Lys Val 130 135 140 Leu Val Glu Ser Ala Lys Gln Ala Arg Glu Lys Ile Gly Ala Thr Ile 145 150 155 160 <210> 231 <211> 1326 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1303) <223> RXN02648 <400> 231 atgaataaaa ttccgggtgc agtgaccgta ggtgaggtaa acgcggttag agtcgaatga 60 gagtttgata ctttctttcg acttttagat tggattttca atg agc cag aac cgc 115 Met Ser Gln Asn Arg 1 5 atc agg acc act cac gtt ggt tcc ttg ccc cgt acc cca gag cta ctt 163 Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg Thr Pro Glu Leu Leu 10 15 20 gat gca aac atc aag cgt tct aac ggt gag att ggg gag gag gaa ttc 211 Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile Gly Glu Glu Glu Phe 25 30 35 ttc cag att ctg cag tct tct gta gat gac gtg atc aag cgc cag gtt 259 Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val Ile Lys Arg Gln Val 40 45 50 gac ctg ggt atc gac atc ctt aac gag ggc gaa tac ggc cac gtc acc 307 Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu Tyr Gly His Val Thr 55 60 65 tcc ggt gca gtt gac ttc ggt gca tgg tgg aac tac tcc ttc acc cgc 355 Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn Tyr Ser Phe Thr Arg 70 75 80 85 ctg ggc gga ctg acc atg acc gat acc gac cgt tgg gca agc cag gaa 403 Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg Trp Ala Ser Gln Glu 90 95 100 gca gtg cgt tcc acc cct ggc aac atc gag ctg acc agc ttc tct gat 451 Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu Thr Ser Phe Ser Asp 105 110 115 cgt cgc gac cgc gca ttg ttc agc gaa gca tac gag gat cca gta tct 499 Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr Glu Asp Pro Val Ser 120 125 130 ggc atc ttc acc ggt cgc gct tct gtg ggc aac cca gag ttc acc gga 547 Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn Pro Glu Phe Thr Gly 135 140 145 cct att acc tac att ggc cag gaa gaa act cag acg gat gtt gat ctg 595 Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln Thr Asp Val Asp Leu 150 155 160 165 ctg aag aag ggc atg aac gca gcg gga gct acc gac ggc ttc gtt gca 643 Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr Asp Gly Phe Val Ala 170 175 180 gca cta tcc cca gga tct gca gct cga ttg acc aac aag ttc tac gac 691 Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr Asn Lys Phe Tyr Asp 185 190 195 act gat gaa gaa gtc gtc gca gca tgt gct gat gcg ctt tcc cag gaa 739 Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp Ala Leu Ser Gln Glu 200 205 210 tac aag atc atc acc gat gca ggt ctg acc gtt cag ctc gac gca ccg 787 Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val Gln Leu Asp Ala Pro 215 220 225 gac ttg gca gaa gca tgg gat cag atc aac cca gag cca agc gtg aag 835 Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro Ser Val Lys 230 235 240 245 gat tac ttg gac tgg atc ggt aca cgc atc gat gcc atc aac agt gca 883 Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile Asn Ser Ala 250 255 260 gtg aag ggc ctt cca aag gaa cag acc cgc ctg cac atc tgc tgg ggc 931 Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile Cys Trp Gly 265 270 275 tct tgg cac gga cca cac gtc act gac atc cca ttc ggt gac atc att 979 Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly Asp Ile Ile 280 285 290 ggt gag atc ctg cgc gca gag gtc ggt ggc ttc tcc ttc gaa ggc gca 1027 Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe Glu Gly Ala 295 300 305 tct cct cgt cac gca cac gag tgg cgt gta tgg gaa gaa aac aag ctt 1075 Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu Asn Lys Leu 310 315 320 325 cct gaa ggc tct gtt atc tac cct ggt gtt gtg tct cac tcc atc aac 1123 Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His Ser Ile Asn 330 335 340 gct gtg gag cac cca cgc ctg gtt gct gat cgt atc gtt cag ttc gcc 1171 Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val Gln Phe Ala 345 350 355 aag ctt gtt ggc cct gag aac gtc att gcg tcc act gac tgt ggt ctg 1219 Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp Cys Gly Leu 360 365 370 ggc gga cgt ctg cat tcc cag atc gca tgg gca aag ctg gag tcc cta 1267 Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu Glu Ser Leu 375 380 385 gta gag ggc gct cgc att gca tca aag gaa ctg ttc taagctagac 1313 Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 390 395 400 aacgagggtt gct 1326 <210> 232 <211> 401 <212> PRT <213> Corynebacterium glutamicum <400> 232 Met Ser Gln Asn Arg Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg 1 5 10 15 Thr Pro Glu Leu Leu Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile 20 25 30 Gly Glu Glu Glu Phe Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val 35 40 45 Ile Lys Arg Gln Val Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu 50 55 60 Tyr Gly His Val Thr Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn 65 70 75 80 Tyr Ser Phe Thr Arg Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg 85 90 95 Trp Ala Ser Gln Glu Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu 100 105 110 Thr Ser Phe Ser Asp Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr 115 120 125 Glu Asp Pro Val Ser Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn 130 135 140 Pro Glu Phe Thr Gly Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln 145 150 155 160 Thr Asp Val Asp Leu Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr 165 170 175 Asp Gly Phe Val Ala Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr 180 185 190 Asn Lys Phe Tyr Asp Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp 195 200 205 Ala Leu Ser Gln Glu Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val 210 215 220 Gln Leu Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro 225 230 235 240 Glu Pro Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp 245 250 255 Ala Ile Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu 260 265 270 His Ile Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro 275 280 285 Phe Gly Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe 290 295 300 Ser Phe Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp 305 310 315 320 Glu Glu Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val 325 330 335 Ser His Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg 340 345 350 Ile Val Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser 355 360 365 Thr Asp Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala 370 375 380 Lys Leu Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu 385 390 395 400 Phe <210> 233 <211> 548 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(525) <223> FRXA02648 <400> 233 gac gca ccg gac ttg gca gaa gca tgg gat cag atc aac cca gag cca 48 Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro 1 5 10 15 agc gtg aag gat tac ttg gac tgg atc ggt aca cgc atc gat gcc atc 96 Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile 20 25 30 aac agt gca gtg aag ggc ctt cca aag gaa cag acc cgc ctg cac atc 144 Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile 35 40 45 tgc tgg ggc tct tgg cac gga cca cac gtc act gac atc cca ttc ggt 192 Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly 50 55 60 gac atc att ggt gag atc ctg cgc gca gag gtc ggt ggc ttc tcc ttc 240 Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe 65 70 75 80 gaa ggc gca tct cct cgt cac gca cac gag tgg cgt gta tgg gaa gaa 288 Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu 85 90 95 aac aag ctt cct gaa ggc tct gtt atc tac cct ggt gtt gtg tct cac 336 Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His 100 105 110 tcc atc aac gct gtg gag cac cca cgc ctg gtt gct gat cgt atc gtt 384 Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val 115 120 125 cag ttc gcc aag ctt gtt ggc cct gag aac gtc att gcg tcc act gac 432 Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp 130 135 140 tgt ggt ctg ggc gga cgt ctg cat tcc cag atc gca tgg gca aag ctg 480 Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu 145 150 155 160 gag tcc cta gta gag ggc gct cgc att gca tca aag gaa ctg ttc 525 Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 165 170 175 taagctagac aacgagggtt gct 548 <210> 234 <211> 175 <212> PRT <213> Corynebacterium glutamicum <400> 234 Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro 1 5 10 15 Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile 20 25 30 Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile 35 40 45 Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly 50 55 60 Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe 65 70 75 80 Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu 85 90 95 Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His 100 105 110 Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val 115 120 125 Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp 130 135 140 Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu 145 150 155 160 Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 165 170 175 <210> 235 <211> 784 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(784) <223> FRXA02658 <400> 235 atgaataaaa ttccgggtgc agtgaccgta ggtgaggtaa acgcggttag agtcgaatga 60 gagtttgata ctttctttcg acttttagat tggattttca atg agc cag aac cgc 115 Met Ser Gln Asn Arg 1 5 atc agg acc act cac gtt ggt tcc ttg ccc cgt acc cca gag cta ctt 163 Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg Thr Pro Glu Leu Leu 10 15 20 gat gca aac atc aag cgt tct aac ggt gag att ggg gag gag gaa ttc 211 Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile Gly Glu Glu Glu Phe 25 30 35 ttc cag att ctg cag tct tct gta gat gac gtg atc aag cgc cag gtt 259 Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val Ile Lys Arg Gln Val 40 45 50 gac ctg ggt atc gac atc ctt aac gag ggc gaa tac ggc cac gtc acc 307 Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu Tyr Gly His Val Thr 55 60 65 tcc ggt gca gtt gac ttc ggt gca tgg tgg aac tac tcc ttc acc cgc 355 Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn Tyr Ser Phe Thr Arg 70 75 80 85 ctg ggc gga ctg acc atg acc gat acc gac cgt tgg gca agc cag gaa 403 Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg Trp Ala Ser Gln Glu 90 95 100 gca gtg cgt tcc acc cct ggc aac atc gag ctg acc agc ttc tct gat 451 Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu Thr Ser Phe Ser Asp 105 110 115 cgt cgc gac cgc gca ttg ttc agc gaa gca tac gag gat cca gta tct 499 Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr Glu Asp Pro Val Ser 120 125 130 ggc atc ttc acc ggt cgc gct tct gtg ggc aac cca gag ttc acc gga 547 Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn Pro Glu Phe Thr Gly 135 140 145 cct att acc tac att ggc cag gaa gaa act cag acg gat gtt gat ctg 595 Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln Thr Asp Val Asp Leu 150 155 160 165 ctg aag aag ggc atg aac gca gcg gga gct acc gac ggc ttc gtt gca 643 Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr Asp Gly Phe Val Ala 170 175 180 gca cta tcc cca gga tct gca gct cga ttg acc aac aag ttc tac gac 691 Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr Asn Lys Phe Tyr Asp 185 190 195 act gat gaa gaa gtc gtc gca gca tgt gct gat gcg ctt tcc cag gaa 739 Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp Ala Leu Ser Gln Glu 200 205 210 tac aag atc atc acc gat gca ggt ctg acc gtt cag ctc gac gca 784 Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val Gln Leu Asp Ala 215 220 225 <210> 236 <211> 228 <212> PRT <213> Corynebacterium glutamicum <400> 236 Met Ser Gln Asn Arg Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg 1 5 10 15 Thr Pro Glu Leu Leu Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile 20 25 30 Gly Glu Glu Glu Phe Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val 35 40 45 Ile Lys Arg Gln Val Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu 50 55 60 Tyr Gly His Val Thr Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn 65 70 75 80 Tyr Ser Phe Thr Arg Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg 85 90 95 Trp Ala Ser Gln Glu Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu 100 105 110 Thr Ser Phe Ser Asp Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr 115 120 125 Glu Asp Pro Val Ser Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn 130 135 140 Pro Glu Phe Thr Gly Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln 145 150 155 160 Thr Asp Val Asp Leu Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr 165 170 175 Asp Gly Phe Val Ala Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr 180 185 190 Asn Lys Phe Tyr Asp Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp 195 200 205 Ala Leu Ser Gln Glu Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val 210 215 220 Gln Leu Asp Ala 225 <210> 237 <211> 408 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(385) <223> RXC02238 <400> 237 ggcgcttagc caaaacatag agcggtaggg tatgcttatc cgattgagca acctttcccg 60 ctcttaacac tactgtccat atacttttga aaaggtgtca gtg acc aac gtg agc 115 Val Thr Asn Val Ser 1 5 aac gag acc aac gcc acc aag gcc gtc ttc gat ccg cca gtg ggc att 163 Asn Glu Thr Asn Ala Thr Lys Ala Val Phe Asp Pro Pro Val Gly Ile 10 15 20 acc gct cct ccg atc gat gaa ctg ctg gat aag gtc act tcc aag tac 211 Thr Ala Pro Pro Ile Asp Glu Leu Leu Asp Lys Val Thr Ser Lys Tyr 25 30 35 gcc ctc gtg atc ttc gca gcc aag cgt gcg cgc cag atc aac agc ttc 259 Ala Leu Val Ile Phe Ala Ala Lys Arg Ala Arg Gln Ile Asn Ser Phe 40 45 50 tac cat cag gca gat gag gga gta ttc gag ttc atc gga cca ttg gtt 307 Tyr His Gln Ala Asp Glu Gly Val Phe Glu Phe Ile Gly Pro Leu Val 55 60 65 act ccg cag cca ggc gaa aag cca ctt tct att gct ctg cgt gag atc 355 Thr Pro Gln Pro Gly Glu Lys Pro Leu Ser Ile Ala Leu Arg Glu Ile 70 75 80 85 aat gca ggt ctg ttg gac cac gag gaa ggt taaaagacct tataacttca 405 Asn Ala Gly Leu Leu Asp His Glu Glu Gly 90 95 cac 408 <210> 238 <211> 95 <212> PRT <213> Corynebacterium glutamicum <400> 238 Val Thr Asn Val Ser Asn Glu Thr Asn Ala Thr Lys Ala Val Phe Asp 1 5 10 15 Pro Pro Val Gly Ile Thr Ala Pro Pro Ile Asp Glu Leu Leu Asp Lys 20 25 30 Val Thr Ser Lys Tyr Ala Leu Val Ile Phe Ala Ala Lys Arg Ala Arg 35 40 45 Gln Ile Asn Ser Phe Tyr His Gln Ala Asp Glu Gly Val Phe Glu Phe 50 55 60 Ile Gly Pro Leu Val Thr Pro Gln Pro Gly Glu Lys Pro Leu Ser Ile 65 70 75 80 Ala Leu Arg Glu Ile Asn Ala Gly Leu Leu Asp His Glu Glu Gly 85 90 95 <210> 239 <211> 1827 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1804) <223> RXC00128 <400> 239 ccattttccg tttggtcttg cctaaagaac cgcatggaaa ttatcgtgaa gcaccgatcc 60 cgttgatcgc tccagagaca ccgtgggaag gggagcagca gtg agt aaa att tcg 115 Val Ser Lys Ile Ser 1 5 acg aaa ctg aag gcc ctc acc gcg gtg ctg tct gtg acc act ctg gtg 163 Thr Lys Leu Lys Ala Leu Thr Ala Val Leu Ser Val Thr Thr Leu Val 10 15 20 gct ggg tgt tcc acg ctt ccg cag aac acg gat ccg caa gtg ctg cgc 211 Ala Gly Cys Ser Thr Leu Pro Gln Asn Thr Asp Pro Gln Val Leu Arg 25 30 35 tca ttt tcc ggg tcc caa agc aca caa gag ata gca ggg ccg acc ccg 259 Ser Phe Ser Gly Ser Gln Ser Thr Gln Glu Ile Ala Gly Pro Thr Pro 40 45 50 aat caa gat ccg gat ttg ttg atc cgc ggc ttc ttc agc gca ggt gcg 307 Asn Gln Asp Pro Asp Leu Leu Ile Arg Gly Phe Phe Ser Ala Gly Ala 55 60 65 tat ccg act cag cag tat gaa gcg gcg aag gcg tat ctg acg gaa ggg 355 Tyr Pro Thr Gln Gln Tyr Glu Ala Ala Lys Ala Tyr Leu Thr Glu Gly 70 75 80 85 acg cgc agc acg tgg aat ccg gct gcg tcg act cgt att ttg gat cgc 403 Thr Arg Ser Thr Trp Asn Pro Ala Ala Ser Thr Arg Ile Leu Asp Arg 90 95 100 att gat ctg aac act ctg cca ggt tcg acg aat gcg gaa cga acg att 451 Ile Asp Leu Asn Thr Leu Pro Gly Ser Thr Asn Ala Glu Arg Thr Ile 105 110 115 gcg atc cgt gga acg cag gtc gga acg ttg ctc agc ggt ggc gtg tat 499 Ala Ile Arg Gly Thr Gln Val Gly Thr Leu Leu Ser Gly Gly Val Tyr 120 125 130 cag ccg gag aat gcg gag ttt gaa gct gag atc acg atg cgt cgg gaa 547 Gln Pro Glu Asn Ala Glu Phe Glu Ala Glu Ile Thr Met Arg Arg Glu 135 140 145 gat ggg gag tgg cgt atc gat gct ttg ccg gac ggg att tta tta gag 595 Asp Gly Glu Trp Arg Ile Asp Ala Leu Pro Asp Gly Ile Leu Leu Glu 150 155 160 165 aga aac gat ctg cgg aac cat tac act ccg cac gat gtg tat ttc ttt 643 Arg Asn Asp Leu Arg Asn His Tyr Thr Pro His Asp Val Tyr Phe Phe 170 175 180 gat cct tct ggc cag gtg ttg gtg ggg gat cgg cgt tgg ttg ttc aat 691 Asp Pro Ser Gly Gln Val Leu Val Gly Asp Arg Arg Trp Leu Phe Asn 185 190 195 gag tcg cag tcg atg tcc acg gtg ctg atg gcc ctt ctg gtt aat ggt 739 Glu Ser Gln Ser Met Ser Thr Val Leu Met Ala Leu Leu Val Asn Gly 200 205 210 cct tcg ccg gca att tct cct ggt gtg gtc aat cag ctg tcc acg gat 787 Pro Ser Pro Ala Ile Ser Pro Gly Val Val Asn Gln Leu Ser Thr Asp 215 220 225 gcg tcg ttc gtg ggg ttc aat gat ggg gag tat cag ttc act ggt ttg 835 Ala Ser Phe Val Gly Phe Asn Asp Gly Glu Tyr Gln Phe Thr Gly Leu 230 235 240 245 gga aat ttg gat gat gat gcg cgt ttg cgt ttc gcc gcc cag gcc gtg 883 Gly Asn Leu Asp Asp Asp Ala Arg Leu Arg Phe Ala Ala Gln Ala Val 250 255 260 tgg acg ttg gcg cat gct gat gtc gca ggc ccc tac act ttg gtc gct 931 Trp Thr Leu Ala His Ala Asp Val Ala Gly Pro Tyr Thr Leu Val Ala 265 270 275 gac ggc gcg ccg ttg ctg tcg gag ttc cca acg ctc acc acc gat gac 979 Asp Gly Ala Pro Leu Leu Ser Glu Phe Pro Thr Leu Thr Thr Asp Asp 280 285 290 ctc gcc gaa tac aac cca gag gct tac acc aac acg gtg tcc acg ttg 1027 Leu Ala Glu Tyr Asn Pro Glu Ala Tyr Thr Asn Thr Val Ser Thr Leu 295 300 305 ttt gcg ttg cag gat gga tcg ttg tcg agg gtc agt tcc ggc aat gtg 1075 Phe Ala Leu Gln Asp Gly Ser Leu Ser Arg Val Ser Ser Gly Asn Val 310 315 320 325 agt cca cta cag ggc att tgg agc ggt gga gat atc gat tct gca gcg 1123 Ser Pro Leu Gln Gly Ile Trp Ser Gly Gly Asp Ile Asp Ser Ala Ala 330 335 340 att tcc tcc tcc gcc aat gtg gtg gca gcg gta cgc cac gaa aac aac 1171 Ile Ser Ser Ser Ala Asn Val Val Ala Ala Val Arg His Glu Asn Asn 345 350 355 gag gca gtg ctt act gtt ggc tcc atg gaa ggc gtg act tca gat gcg 1219 Glu Ala Val Leu Thr Val Gly Ser Met Glu Gly Val Thr Ser Asp Ala 360 365 370 ttg agg agt gaa acg atc act cgt ccc acc ttt gaa tac gcg tcg agt 1267 Leu Arg Ser Glu Thr Ile Thr Arg Pro Thr Phe Glu Tyr Ala Ser Ser 375 380 385 ggg ttg tgg gct gtg gtg gat ggg gag acg cct gtc cga gtc gca cga 1315 Gly Leu Trp Ala Val Val Asp Gly Glu Thr Pro Val Arg Val Ala Arg 390 395 400 405 tcg gca aca acc ggt gag ctc gtc cag acg gag gcg gag att gtg ctg 1363 Ser Ala Thr Thr Gly Glu Leu Val Gln Thr Glu Ala Glu Ile Val Leu 410 415 420 cca agg gat gtg acg ggt ccg atc tct gaa ttc caa ctg tca cga act 1411 Pro Arg Asp Val Thr Gly Pro Ile Ser Glu Phe Gln Leu Ser Arg Thr 425 430 435 ggg gtc cgg gcc gcc atg atc att gaa ggc aag gtg tac gtg ggc gtc 1459 Gly Val Arg Ala Ala Met Ile Ile Glu Gly Lys Val Tyr Val Gly Val 440 445 450 gta acg cgt cct ggt ccg ggc gag cgg cgc gtg aca aat atc acg gag 1507 Val Thr Arg Pro Gly Pro Gly Glu Arg Arg Val Thr Asn Ile Thr Glu 455 460 465 gtg gcg ccg agc ttg ggc gag gcg gcg ctg tcg atc aac tgg cgc cca 1555 Val Ala Pro Ser Leu Gly Glu Ala Ala Leu Ser Ile Asn Trp Arg Pro 470 475 480 485 gac ggc att ttg ctt gtg ggc acg tca att cca gag acg ccg ctg tgg 1603 Asp Gly Ile Leu Leu Val Gly Thr Ser Ile Pro Glu Thr Pro Leu Trp 490 495 500 cgc gtc gag cag gac gga tcg gcg att tcg tcg atg ccg agc ggg aat 1651 Arg Val Glu Gln Asp Gly Ser Ala Ile Ser Ser Met Pro Ser Gly Asn 505 510 515 ctc agc gcg ccg gtg gtg gcg gtg gca agt tcc gcg acg acg gtc tac 1699 Leu Ser Ala Pro Val Val Ala Val Ala Ser Ser Ala Thr Thr Val Tyr 520 525 530 gtc act gat tcg cat gcg atg ctt cag ctg ccg act gcc gat aat gat 1747 Val Thr Asp Ser His Ala Met Leu Gln Leu Pro Thr Ala Asp Asn Asp 535 540 545 att tgg cgc gag gtg ccc ggt ttg ctg ggc acg cgt gcg gcg ccg gtg 1795 Ile Trp Arg Glu Val Pro Gly Leu Leu Gly Thr Arg Ala Ala Pro Val 550 555 560 565 gtt gcg tac tgatggagct gttcttcccg cgc 1827 Val Ala Tyr <210> 240 <211> 568 <212> PRT <213> Corynebacterium glutamicum <400> 240 Val Ser Lys Ile Ser Thr Lys Leu Lys Ala Leu Thr Ala Val Leu Ser 1 5 10 15 Val Thr Thr Leu Val Ala Gly Cys Ser Thr Leu Pro Gln Asn Thr Asp 20 25 30 Pro Gln Val Leu Arg Ser Phe Ser Gly Ser Gln Ser Thr Gln Glu Ile 35 40 45 Ala Gly Pro Thr Pro Asn Gln Asp Pro Asp Leu Leu Ile Arg Gly Phe 50 55 60 Phe Ser Ala Gly Ala Tyr Pro Thr Gln Gln Tyr Glu Ala Ala Lys Ala 65 70 75 80 Tyr Leu Thr Glu Gly Thr Arg Ser Thr Trp Asn Pro Ala Ala Ser Thr 85 90 95 Arg Ile Leu Asp Arg Ile Asp Leu Asn Thr Leu Pro Gly Ser Thr Asn 100 105 110 Ala Glu Arg Thr Ile Ala Ile Arg Gly Thr Gln Val Gly Thr Leu Leu 115 120 125 Ser Gly Gly Val Tyr Gln Pro Glu Asn Ala Glu Phe Glu Ala Glu Ile 130 135 140 Thr Met Arg Arg Glu Asp Gly Glu Trp Arg Ile Asp Ala Leu Pro Asp 145 150 155 160 Gly Ile Leu Leu Glu Arg Asn Asp Leu Arg Asn His Tyr Thr Pro His 165 170 175 Asp Val Tyr Phe Phe Asp Pro Ser Gly Gln Val Leu Val Gly Asp Arg 180 185 190 Arg Trp Leu Phe Asn Glu Ser Gln Ser Met Ser Thr Val Leu Met Ala 195 200 205 Leu Leu Val Asn Gly Pro Ser Pro Ala Ile Ser Pro Gly Val Val Asn 210 215 220 Gln Leu Ser Thr Asp Ala Ser Phe Val Gly Phe Asn Asp Gly Glu Tyr 225 230 235 240 Gln Phe Thr Gly Leu Gly Asn Leu Asp Asp Asp Ala Arg Leu Arg Phe 245 250 255 Ala Ala Gln Ala Val Trp Thr Leu Ala His Ala Asp Val Ala Gly Pro 260 265 270 Tyr Thr Leu Val Ala Asp Gly Ala Pro Leu Leu Ser Glu Phe Pro Thr 275 280 285 Leu Thr Thr Asp Asp Leu Ala Glu Tyr Asn Pro Glu Ala Tyr Thr Asn 290 295 300 Thr Val Ser Thr Leu Phe Ala Leu Gln Asp Gly Ser Leu Ser Arg Val 305 310 315 320 Ser Ser Gly Asn Val Ser Pro Leu Gln Gly Ile Trp Ser Gly Gly Asp 325 330 335 Ile Asp Ser Ala Ala Ile Ser Ser Ser Ala Asn Val Val Ala Ala Val 340 345 350 Arg His Glu Asn Asn Glu Ala Val Leu Thr Val Gly Ser Met Glu Gly 355 360 365 Val Thr Ser Asp Ala Leu Arg Ser Glu Thr Ile Thr Arg Pro Thr Phe 370 375 380 Glu Tyr Ala Ser Ser Gly Leu Trp Ala Val Val Asp Gly Glu Thr Pro 385 390 395 400 Val Arg Val Ala Arg Ser Ala Thr Thr Gly Glu Leu Val Gln Thr Glu 405 410 415 Ala Glu Ile Val Leu Pro Arg Asp Val Thr Gly Pro Ile Ser Glu Phe 420 425 430 Gln Leu Ser Arg Thr Gly Val Arg Ala Ala Met Ile Ile Glu Gly Lys 435 440 445 Val Tyr Val Gly Val Val Thr Arg Pro Gly Pro Gly Glu Arg Arg Val 450 455 460 Thr Asn Ile Thr Glu Val Ala Pro Ser Leu Gly Glu Ala Ala Leu Ser 465 470 475 480 Ile Asn Trp Arg Pro Asp Gly Ile Leu Leu Val Gly Thr Ser Ile Pro 485 490 495 Glu Thr Pro Leu Trp Arg Val Glu Gln Asp Gly Ser Ala Ile Ser Ser 500 505 510 Met Pro Ser Gly Asn Leu Ser Ala Pro Val Val Ala Val Ala Ser Ser 515 520 525 Ala Thr Thr Val Tyr Val Thr Asp Ser His Ala Met Leu Gln Leu Pro 530 535 540 Thr Ala Asp Asn Asp Ile Trp Arg Glu Val Pro Gly Leu Leu Gly Thr 545 550 555 560 Arg Ala Ala Pro Val Val Ala Tyr 565 <210> 241 <211> 1344 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1321) <223> RXA02240 <400> 241 cagctagacc actgacattg cagttttaga cagcttggtc tatattggtt ttttgtattt 60 aagactattt attctcaact tcttcgaaag aagggtattt gtg gct cag cca acc 115 Val Ala Gln Pro Thr 1 5 gcc gtc cgt ttg ttc acc agt gaa tct gta act gag gga cat cca gac 163 Ala Val Arg Leu Phe Thr Ser Glu Ser Val Thr Glu Gly His Pro Asp 10 15 20 aaa ata tgt gat gct att tcc gat acc att ttg gac gcg ctg ctc gaa 211 Lys Ile Cys Asp Ala Ile Ser Asp Thr Ile Leu Asp Ala Leu Leu Glu 25 30 35 aaa gat ccg cag tcg cgc gtc gca gtg gaa act gtg gtc acc acc gga 259 Lys Asp Pro Gln Ser Arg Val Ala Val Glu Thr Val Val Thr Thr Gly 40 45 50 atc gtc cat gtt gtt ggc gag gtc cgt acc agc gct tac gta gag atc 307 Ile Val His Val Val Gly Glu Val Arg Thr Ser Ala Tyr Val Glu Ile 55 60 65 cct caa tta gtc cgc aac aag ctc atc gaa atc gga ttc aac tcc tct 355 Pro Gln Leu Val Arg Asn Lys Leu Ile Glu Ile Gly Phe Asn Ser Ser 70 75 80 85 gag gtt gga ttc gac gga cgc acc tgt ggc gtc tca gta tcc atc ggt 403 Glu Val Gly Phe Asp Gly Arg Thr Cys Gly Val Ser Val Ser Ile Gly 90 95 100 gag cag tcc cag gaa atc gct gac ggc gtg gat aac tcc gac gaa gcc 451 Glu Gln Ser Gln Glu Ile Ala Asp Gly Val Asp Asn Ser Asp Glu Ala 105 110 115 cgc acc aac ggc gac gtt gaa gaa gac gac cgc gca ggt gct ggc gac 499 Arg Thr Asn Gly Asp Val Glu Glu Asp Asp Arg Ala Gly Ala Gly Asp 120 125 130 cag ggc ctg atg ttc ggc tac gcc acc aac gaa acc gaa gag tac atg 547 Gln Gly Leu Met Phe Gly Tyr Ala Thr Asn Glu Thr Glu Glu Tyr Met 135 140 145 cct ctt cct atc gcg ttg gcg cac cga ctg tca cgt cgt ctg acc cag 595 Pro Leu Pro Ile Ala Leu Ala His Arg Leu Ser Arg Arg Leu Thr Gln 150 155 160 165 gtt cgt aaa gag ggc atc gtt cct cac ctg cgt cca gac gga aaa acc 643 Val Arg Lys Glu Gly Ile Val Pro His Leu Arg Pro Asp Gly Lys Thr 170 175 180 cag gtc acc ttc gca tac gat gcg caa gac cgc cct agc cac ctg gat 691 Gln Val Thr Phe Ala Tyr Asp Ala Gln Asp Arg Pro Ser His Leu Asp 185 190 195 acc gtt gtc atc tcc acc cag cac gac cca gaa gtt gac cgt gca tgg 739 Thr Val Val Ile Ser Thr Gln His Asp Pro Glu Val Asp Arg Ala Trp 200 205 210 ttg gaa acc caa ctg cgc gaa cac gtc att gat tgg gta atc aaa gac 787 Leu Glu Thr Gln Leu Arg Glu His Val Ile Asp Trp Val Ile Lys Asp 215 220 225 gca ggc att gag gat ctg gca acc ggt gag atc acc gtg ttg atc aac 835 Ala Gly Ile Glu Asp Leu Ala Thr Gly Glu Ile Thr Val Leu Ile Asn 230 235 240 245 cct tca ggt tcc ttc att ctg ggt ggc ccc atg ggt gat gcg ggt ctg 883 Pro Ser Gly Ser Phe Ile Leu Gly Gly Pro Met Gly Asp Ala Gly Leu 250 255 260 acc ggc cgc aag atc atc gtg gat acc tac ggt ggc atg gct cgc cat 931 Thr Gly Arg Lys Ile Ile Val Asp Thr Tyr Gly Gly Met Ala Arg His 265 270 275 ggt ggt gga gca ttc tcc ggt aag gat cca agc aag gtg gac cgc tct 979 Gly Gly Gly Ala Phe Ser Gly Lys Asp Pro Ser Lys Val Asp Arg Ser 280 285 290 gct gca tac gcc atg cgt tgg gta gca aag aac atc gtg gca gca ggc 1027 Ala Ala Tyr Ala Met Arg Trp Val Ala Lys Asn Ile Val Ala Ala Gly 295 300 305 ctt gct gat cgc gct gaa gtt cag gtt gca tac gcc att gga cgc gca 1075 Leu Ala Asp Arg Ala Glu Val Gln Val Ala Tyr Ala Ile Gly Arg Ala 310 315 320 325 aag cca gtc gga ctt tac gtt gaa acc ttt gac acc aac aag gaa ggc 1123 Lys Pro Val Gly Leu Tyr Val Glu Thr Phe Asp Thr Asn Lys Glu Gly 330 335 340 ctg agc gac gag cag att cag gct gcc gtg ttg gag gtc ttt gac ctg 1171 Leu Ser Asp Glu Gln Ile Gln Ala Ala Val Leu Glu Val Phe Asp Leu 345 350 355 cgt cca gca gca att atc cgt gag ctt gat ctg ctt cgt ccg atc tac 1219 Arg Pro Ala Ala Ile Ile Arg Glu Leu Asp Leu Leu Arg Pro Ile Tyr 360 365 370 gct gac act gct gcc tac ggc cac ttt ggt cgc act gat ttg gac ctt 1267 Ala Asp Thr Ala Ala Tyr Gly His Phe Gly Arg Thr Asp Leu Asp Leu 375 380 385 cct tgg gag gct atc gac cgc gtt gat gaa ctt cgc gca gcc ctc aag 1315 Pro Trp Glu Ala Ile Asp Arg Val Asp Glu Leu Arg Ala Ala Leu Lys 390 395 400 405 ttg gcc taaaaatctg atgtagtatc ttc 1344 Leu Ala <210> 242 <211> 407 <212> PRT <213> Corynebacterium glutamicum <400> 242 Val Ala Gln Pro Thr Ala Val Arg Leu Phe Thr Ser Glu Ser Val Thr 1 5 10 15 Glu Gly His Pro Asp Lys Ile Cys Asp Ala Ile Ser Asp Thr Ile Leu 20 25 30 Asp Ala Leu Leu Glu Lys Asp Pro Gln Ser Arg Val Ala Val Glu Thr 35 40 45 Val Val Thr Thr Gly Ile Val His Val Val Gly Glu Val Arg Thr Ser 50 55 60 Ala Tyr Val Glu Ile Pro Gln Leu Val Arg Asn Lys Leu Ile Glu Ile 65 70 75 80 Gly Phe Asn Ser Ser Glu Val Gly Phe Asp Gly Arg Thr Cys Gly Val 85 90 95 Ser Val Ser Ile Gly Glu Gln Ser Gln Glu Ile Ala Asp Gly Val Asp 100 105 110 Asn Ser Asp Glu Ala Arg Thr Asn Gly Asp Val Glu Glu Asp Asp Arg 115 120 125 Ala Gly Ala Gly Asp Gln Gly Leu Met Phe Gly Tyr Ala Thr Asn Glu 130 135 140 Thr Glu Glu Tyr Met Pro Leu Pro Ile Ala Leu Ala His Arg Leu Ser 145 150 155 160 Arg Arg Leu Thr Gln Val Arg Lys Glu Gly Ile Val Pro His Leu Arg 165 170 175 Pro Asp Gly Lys Thr Gln Val Thr Phe Ala Tyr Asp Ala Gln Asp Arg 180 185 190 Pro Ser His Leu Asp Thr Val Val Ile Ser Thr Gln His Asp Pro Glu 195 200 205 Val Asp Arg Ala Trp Leu Glu Thr Gln Leu Arg Glu His Val Ile Asp 210 215 220 Trp Val Ile Lys Asp Ala Gly Ile Glu Asp Leu Ala Thr Gly Glu Ile 225 230 235 240 Thr Val Leu Ile Asn Pro Ser Gly Ser Phe Ile Leu Gly Gly Pro Met 245 250 255 Gly Asp Ala Gly Leu Thr Gly Arg Lys Ile Ile Val Asp Thr Tyr Gly 260 265 270 Gly Met Ala Arg His Gly Gly Gly Ala Phe Ser Gly Lys Asp Pro Ser 275 280 285 Lys Val Asp Arg Ser Ala Ala Tyr Ala Met Arg Trp Val Ala Lys Asn 290 295 300 Ile Val Ala Ala Gly Leu Ala Asp Arg Ala Glu Val Gln Val Ala Tyr 305 310 315 320 Ala Ile Gly Arg Ala Lys Pro Val Gly Leu Tyr Val Glu Thr Phe Asp 325 330 335 Thr Asn Lys Glu Gly Leu Ser Asp Glu Gln Ile Gln Ala Ala Val Leu 340 345 350 Glu Val Phe Asp Leu Arg Pro Ala Ala Ile Ile Arg Glu Leu Asp Leu 355 360 365 Leu Arg Pro Ile Tyr Ala Asp Thr Ala Ala Tyr Gly His Phe Gly Arg 370 375 380 Thr Asp Leu Asp Leu Pro Trp Glu Ala Ile Asp Arg Val Asp Glu Leu 385 390 395 400 Arg Ala Ala Leu Lys Leu Ala 405 <210> 243 <211> 669 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(646) <223> RXA00780 <400> 243 ccttttaagt ccttctttgc ccgtgaataa ttctctggat agtttccacg tgcagttaag 60 tcacgctgtt agacttgcct gcatgctctc gacaataaaa atg atc cgt gaa gat 115 Met Ile Arg Glu Asp 1 5 ctc gca aac gct cgt gaa cac gat cca gca gcc cga ggc gat tta gaa 163 Leu Ala Asn Ala Arg Glu His Asp Pro Ala Ala Arg Gly Asp Leu Glu 10 15 20 aac gca gtg gtt tac tcc gga ctc cac gcc atc tgg gca cat cga gtt 211 Asn Ala Val Val Tyr Ser Gly Leu His Ala Ile Trp Ala His Arg Val 25 30 35 gcc aac agc tgg tgg aaa tcc ggt ttc cgc ggc ccc gcc cgc gta tta 259 Ala Asn Ser Trp Trp Lys Ser Gly Phe Arg Gly Pro Ala Arg Val Leu 40 45 50 gcc caa ttc acc cga ttc ctc acc ggc att gaa att cac ccc ggt gcc 307 Ala Gln Phe Thr Arg Phe Leu Thr Gly Ile Glu Ile His Pro Gly Ala 55 60 65 acc att ggt cgt cgc ttt ttt att gac cac gga atg gga atc gtc atc 355 Thr Ile Gly Arg Arg Phe Phe Ile Asp His Gly Met Gly Ile Val Ile 70 75 80 85 ggc gaa acc gct gaa atc ggc gaa ggc gtc atg ctc tac cac ggc gtc 403 Gly Glu Thr Ala Glu Ile Gly Glu Gly Val Met Leu Tyr His Gly Val 90 95 100 acc ctc ggc gga cag gtt ctc acc caa acc aag cgc cac ccc acg ctc 451 Thr Leu Gly Gly Gln Val Leu Thr Gln Thr Lys Arg His Pro Thr Leu 105 110 115 tgc gac aac gtg aca gtc ggc gcg ggc gca aaa atc tta ggt ccc atc 499 Cys Asp Asn Val Thr Val Gly Ala Gly Ala Lys Ile Leu Gly Pro Ile 120 125 130 acc atc ggc gaa ggc tcc gca att ggc gcc aat gca gtt gtc acc aaa 547 Thr Ile Gly Glu Gly Ser Ala Ile Gly Ala Asn Ala Val Val Thr Lys 135 140 145 gac gtg ccg gca gaa cac atc gca gtc gga att cct gcg gta gca cgc 595 Asp Val Pro Ala Glu His Ile Ala Val Gly Ile Pro Ala Val Ala Arg 150 155 160 165 cca cgt ggc aag aca gag aag atc aag ctc gtc gat ccg gac tat tac 643 Pro Arg Gly Lys Thr Glu Lys Ile Lys Leu Val Asp Pro Asp Tyr Tyr 170 175 180 att taagaacagt tagcgcccta cct 669 Ile <210> 244 <211> 182 <212> PRT <213> Corynebacterium glutamicum <400> 244 Met Ile Arg Glu Asp Leu Ala Asn Ala Arg Glu His Asp Pro Ala Ala 1 5 10 15 Arg Gly Asp Leu Glu Asn Ala Val Val Tyr Ser Gly Leu His Ala Ile 20 25 30 Trp Ala His Arg Val Ala Asn Ser Trp Trp Lys Ser Gly Phe Arg Gly 35 40 45 Pro Ala Arg Val Leu Ala Gln Phe Thr Arg Phe Leu Thr Gly Ile Glu 50 55 60 Ile His Pro Gly Ala Thr Ile Gly Arg Arg Phe Phe Ile Asp His Gly 65 70 75 80 Met Gly Ile Val Ile Gly Glu Thr Ala Glu Ile Gly Glu Gly Val Met 85 90 95 Leu Tyr His Gly Val Thr Leu Gly Gly Gln Val Leu Thr Gln Thr Lys 100 105 110 Arg His Pro Thr Leu Cys Asp Asn Val Thr Val Gly Ala Gly Ala Lys 115 120 125 Ile Leu Gly Pro Ile Thr Ile Gly Glu Gly Ser Ala Ile Gly Ala Asn 130 135 140 Ala Val Val Thr Lys Asp Val Pro Ala Glu His Ile Ala Val Gly Ile 145 150 155 160 Pro Ala Val Ala Arg Pro Arg Gly Lys Thr Glu Lys Ile Lys Leu Val 165 170 175 Asp Pro Asp Tyr Tyr Ile 180 <210> 245 <211> 1056 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1033) <223> RXA00779 <400> 245 cagaggccac ttcaagtaga tgtttcgtaa ttgtttacag cgtttacgca agcggtcgac 60 caacaaaaac agcacttcaa tgattggagc accacccgac atg ggc aat gtg tac 115 Met Gly Asn Val Tyr 1 5 aac aac atc acc gaa acc atc ggc cac acc cca ctg gta aag ctg aac 163 Asn Asn Ile Thr Glu Thr Ile Gly His Thr Pro Leu Val Lys Leu Asn 10 15 20 aag ctc acc gaa ggc ctc gac gca act gtc ctg gtc aag ctt gag tca 211 Lys Leu Thr Glu Gly Leu Asp Ala Thr Val Leu Val Lys Leu Glu Ser 25 30 35 ttc aac cca gca aac tcc gtc aag gac cgt atc ggt ctg gcc atc gtt 259 Phe Asn Pro Ala Asn Ser Val Lys Asp Arg Ile Gly Leu Ala Ile Val 40 45 50 gaa gat gca gag aag tcc ggt gca ctg aag cca ggc ggc acc atc gtt 307 Glu Asp Ala Glu Lys Ser Gly Ala Leu Lys Pro Gly Gly Thr Ile Val 55 60 65 gaa gca acc tcc ggc aac acc ggt atc gca ctg gca atg gtc ggc gct 355 Glu Ala Thr Ser Gly Asn Thr Gly Ile Ala Leu Ala Met Val Gly Ala 70 75 80 85 gca cgc gga tac aac gtt gtt ctc acc atg ccg gag acc atg tcc aac 403 Ala Arg Gly Tyr Asn Val Val Leu Thr Met Pro Glu Thr Met Ser Asn 90 95 100 gag cgt cgc gtt ctc ctc cgc gct tac ggt gca gag atc gtt ctt acc 451 Glu Arg Arg Val Leu Leu Arg Ala Tyr Gly Ala Glu Ile Val Leu Thr 105 110 115 cca ggt gca gca ggc atg cag ggt gca aag gac aag gca gac gaa atc 499 Pro Gly Ala Ala Gly Met Gln Gly Ala Lys Asp Lys Ala Asp Glu Ile 120 125 130 gtc gct gaa cgc gaa aac gca gtc ctt gct cgc cag ttc gag aac gag 547 Val Ala Glu Arg Glu Asn Ala Val Leu Ala Arg Gln Phe Glu Asn Glu 135 140 145 gca aac cca cgc gtc aac cgc gac acc acc gcg aag gaa atc ctc gaa 595 Ala Asn Pro Arg Val Asn Arg Asp Thr Thr Ala Lys Glu Ile Leu Glu 150 155 160 165 gac acc gac ggc acc gtt gat atc ttc gtt gca agc ttc ggc acc ggc 643 Asp Thr Asp Gly Thr Val Asp Ile Phe Val Ala Ser Phe Gly Thr Gly 170 175 180 gga acc gtc acc ggc gtt ggc cag gtc ctg aag gaa aac aac gca gac 691 Gly Thr Val Thr Gly Val Gly Gln Val Leu Lys Glu Asn Asn Ala Asp 185 190 195 gta cag gtc tac acc gtc gag cca gaa gcg tcc cca ctt ctg acc gct 739 Val Gln Val Tyr Thr Val Glu Pro Glu Ala Ser Pro Leu Leu Thr Ala 200 205 210 ggc aag gct ggt cca cac aag atc cag ggc atc ggc gca aac ttc atc 787 Gly Lys Ala Gly Pro His Lys Ile Gln Gly Ile Gly Ala Asn Phe Ile 215 220 225 ccc gag gtc ctg gac cgc aag gtt ctc gac gac gtg ctg acc gtc tcc 835 Pro Glu Val Leu Asp Arg Lys Val Leu Asp Asp Val Leu Thr Val Ser 230 235 240 245 aac gaa gac gca atc gca ttc tcc cgc aag ctc gct acc gaa gag ggc 883 Asn Glu Asp Ala Ile Ala Phe Ser Arg Lys Leu Ala Thr Glu Glu Gly 250 255 260 atc ctc ggc ggt atc tcc acc ggc gca aac atc aag gca gct ctt gac 931 Ile Leu Gly Gly Ile Ser Thr Gly Ala Asn Ile Lys Ala Ala Leu Asp 265 270 275 ctt gca gca aag cca gag aac gct ggc aaa acc atc gtc acc gtt gtc 979 Leu Ala Ala Lys Pro Glu Asn Ala Gly Lys Thr Ile Val Thr Val Val 280 285 290 acc gac ttc ggc gag cgc tac gtc tcc acc gtt ctt tac gaa gac atc 1027 Thr Asp Phe Gly Glu Arg Tyr Val Ser Thr Val Leu Tyr Glu Asp Ile 295 300 305 cgc gac taattcttag cgactgttaa cca 1056 Arg Asp 310 <210> 246 <211> 311 <212> PRT <213> Corynebacterium glutamicum <400> 246 Met Gly Asn Val Tyr Asn Asn Ile Thr Glu Thr Ile Gly His Thr Pro 1 5 10 15 Leu Val Lys Leu Asn Lys Leu Thr Glu Gly Leu Asp Ala Thr Val Leu 20 25 30 Val Lys Leu Glu Ser Phe Asn Pro Ala Asn Ser Val Lys Asp Arg Ile 35 40 45 Gly Leu Ala Ile Val Glu Asp Ala Glu Lys Ser Gly Ala Leu Lys Pro 50 55 60 Gly Gly Thr Ile Val Glu Ala Thr Ser Gly Asn Thr Gly Ile Ala Leu 65 70 75 80 Ala Met Val Gly Ala Ala Arg Gly Tyr Asn Val Val Leu Thr Met Pro 85 90 95 Glu Thr Met Ser Asn Glu Arg Arg Val Leu Leu Arg Ala Tyr Gly Ala 100 105 110 Glu Ile Val Leu Thr Pro Gly Ala Ala Gly Met Gln Gly Ala Lys Asp 115 120 125 Lys Ala Asp Glu Ile Val Ala Glu Arg Glu Asn Ala Val Leu Ala Arg 130 135 140 Gln Phe Glu Asn Glu Ala Asn Pro Arg Val Asn Arg Asp Thr Thr Ala 145 150 155 160 Lys Glu Ile Leu Glu Asp Thr Asp Gly Thr Val Asp Ile Phe Val Ala 165 170 175 Ser Phe Gly Thr Gly Gly Thr Val Thr Gly Val Gly Gln Val Leu Lys 180 185 190 Glu Asn Asn Ala Asp Val Gln Val Tyr Thr Val Glu Pro Glu Ala Ser 195 200 205 Pro Leu Leu Thr Ala Gly Lys Ala Gly Pro His Lys Ile Gln Gly Ile 210 215 220 Gly Ala Asn Phe Ile Pro Glu Val Leu Asp Arg Lys Val Leu Asp Asp 225 230 235 240 Val Leu Thr Val Ser Asn Glu Asp Ala Ile Ala Phe Ser Arg Lys Leu 245 250 255 Ala Thr Glu Glu Gly Ile Leu Gly Gly Ile Ser Thr Gly Ala Asn Ile 260 265 270 Lys Ala Ala Leu Asp Leu Ala Ala Lys Pro Glu Asn Ala Gly Lys Thr 275 280 285 Ile Val Thr Val Val Thr Asp Phe Gly Glu Arg Tyr Val Ser Thr Val 290 295 300 Leu Tyr Glu Asp Ile Arg Asp 305 310 <210> 247 <211> 623 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(600) <223> RXN00402 <400> 247 act gac gaa aag gat gga aag cca gta ttg ccc tac ttc gtc act cca 48 Thr Asp Glu Lys Asp Gly Lys Pro Val Leu Pro Tyr Phe Val Thr Pro 1 5 10 15 gat gct gct tac cac gga ttg aag tac gca gac ctt ggt gca cca gcc 96 Asp Ala Ala Tyr His Gly Leu Lys Tyr Ala Asp Leu Gly Ala Pro Ala 20 25 30 ttc ggc ctc aag gtt cgc gtt ggc ctt cta cgc gac acc ggc tcc acc 144 Phe Gly Leu Lys Val Arg Val Gly Leu Leu Arg Asp Thr Gly Ser Thr 35 40 45 ctc tcc gca ttc aac gca tgg gct gca gtc cag ggc atc gac acc ctt 192 Leu Ser Ala Phe Asn Ala Trp Ala Ala Val Gln Gly Ile Asp Thr Leu 50 55 60 tcc ctg cgc ctg gag cgc cac aac gaa aac gcc atc aag gtt gca gaa 240 Ser Leu Arg Leu Glu Arg His Asn Glu Asn Ala Ile Lys Val Ala Glu 65 70 75 80 ttc ctc aac aac cac gag aag gtg gaa aag gtt aac ttc gca ggc ctg 288 Phe Leu Asn Asn His Glu Lys Val Glu Lys Val Asn Phe Ala Gly Leu 85 90 95 aag gat tcc cct tgg tac gca acc aag gaa aag ctt ggc ctg aag tac 336 Lys Asp Ser Pro Trp Tyr Ala Thr Lys Glu Lys Leu Gly Leu Lys Tyr 100 105 110 acc ggc tcc gtt ctc acc ttc gag atc aag ggc ggc aag gat gag gct 384 Thr Gly Ser Val Leu Thr Phe Glu Ile Lys Gly Gly Lys Asp Glu Ala 115 120 125 tgg gca ttt atc gac gcc ctg aag cta cac tcc aac ctt gca aac atc 432 Trp Ala Phe Ile Asp Ala Leu Lys Leu His Ser Asn Leu Ala Asn Ile 130 135 140 ggc gat gtt cgc tcc ctc gtt gtt cac cca gca acc acc acc cat tca 480 Gly Asp Val Arg Ser Leu Val Val His Pro Ala Thr Thr Thr His Ser 145 150 155 160 cag tcc gac gaa gct ggc ctg gca cgc gcg ggc gtt acc cag tcc acc 528 Gln Ser Asp Glu Ala Gly Leu Ala Arg Ala Gly Val Thr Gln Ser Thr 165 170 175 gtc cgc ctg tcc gtt ggc atc gag acc att gat gat atc atc gct gac 576 Val Arg Leu Ser Val Gly Ile Glu Thr Ile Asp Asp Ile Ile Ala Asp 180 185 190 ctc gaa ggc ggc ttt gct gca atc tagctttaaa tagactcacc cca 623 Leu Glu Gly Gly Phe Ala Ala Ile 195 200 <210> 248 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 248 Thr Asp Glu Lys Asp Gly Lys Pro Val Leu Pro Tyr Phe Val Thr Pro 1 5 10 15 Asp Ala Ala Tyr His Gly Leu Lys Tyr Ala Asp Leu Gly Ala Pro Ala 20 25 30 Phe Gly Leu Lys Val Arg Val Gly Leu Leu Arg Asp Thr Gly Ser Thr 35 40 45 Leu Ser Ala Phe Asn Ala Trp Ala Ala Val Gln Gly Ile Asp Thr Leu 50 55 60 Ser Leu Arg Leu Glu Arg His Asn Glu Asn Ala Ile Lys Val Ala Glu 65 70 75 80 Phe Leu Asn Asn His Glu Lys Val Glu Lys Val Asn Phe Ala Gly Leu 85 90 95 Lys Asp Ser Pro Trp Tyr Ala Thr Lys Glu Lys Leu Gly Leu Lys Tyr 100 105 110 Thr Gly Ser Val Leu Thr Phe Glu Ile Lys Gly Gly Lys Asp Glu Ala 115 120 125 Trp Ala Phe Ile Asp Ala Leu Lys Leu His Ser Asn Leu Ala Asn Ile 130 135 140 Gly Asp Val Arg Ser Leu Val Val His Pro Ala Thr Thr Thr His Ser 145 150 155 160 Gln Ser Asp Glu Ala Gly Leu Ala Arg Ala Gly Val Thr Gln Ser Thr 165 170 175 Val Arg Leu Ser Val Gly Ile Glu Thr Ile Asp Asp Ile Ile Ala Asp 180 185 190 Leu Glu Gly Gly Phe Ala Ala Ile 195 200 <210> 249 <211> 599 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(576) <223> FRXA00402 <400> 249 gta ttg ccc tac ttc gtc act cca gat gct gct tac cac gga ttg aag 48 Val Leu Pro Tyr Phe Val Thr Pro Asp Ala Ala Tyr His Gly Leu Lys 1 5 10 15 tac gca gac ctt ggt gca cca gcc ttc ggc ctc aag gtt cgc gtt ggc 96 Tyr Ala Asp Leu Gly Ala Pro Ala Phe Gly Leu Lys Val Arg Val Gly 20 25 30 ctt cta cgc gac acc ggc tcc acc ctc tcc gca ttc aac gca tgg gct 144 Leu Leu Arg Asp Thr Gly Ser Thr Leu Ser Ala Phe Asn Ala Trp Ala 35 40 45 gca gtc cag ggc atc gac acc ctt tcc ctg cgc ctg gag cgc cac aac 192 Ala Val Gln Gly Ile Asp Thr Leu Ser Leu Arg Leu Glu Arg His Asn 50 55 60 gaa aac gcc atc aag gtt gca gaa ttc ctc aac aac cac gag aag gtg 240 Glu Asn Ala Ile Lys Val Ala Glu Phe Leu Asn Asn His Glu Lys Val 65 70 75 80 gaa aag gtt aac ttc gca ggc ctg aag gat tcc cct tgg tac gca acc 288 Glu Lys Val Asn Phe Ala Gly Leu Lys Asp Ser Pro Trp Tyr Ala Thr 85 90 95 aag gaa aag ctt ggc ctg aag tac acc ggc tcc gtt ctc acc ttc gag 336 Lys Glu Lys Leu Gly Leu Lys Tyr Thr Gly Ser Val Leu Thr Phe Glu 100 105 110 atc aag ggc ggc aag gat gag gct tgg gca ttt atc gac gcc ctg aag 384 Ile Lys Gly Gly Lys Asp Glu Ala Trp Ala Phe Ile Asp Ala Leu Lys 115 120 125 cta cac tcc aac ctt gca aac atc ggc gat gtt cgc tcc ctc gtt gtt 432 Leu His Ser Asn Leu Ala Asn Ile Gly Asp Val Arg Ser Leu Val Val 130 135 140 cac cca gca acc acc acc cat tca cag tcc gac gaa gct ggc ctg gca 480 His Pro Ala Thr Thr Thr His Ser Gln Ser Asp Glu Ala Gly Leu Ala 145 150 155 160 cgc gcg ggc gtt acc cag tcc acc gtc cgc ctg tcc gtt ggc atc gag 528 Arg Ala Gly Val Thr Gln Ser Thr Val Arg Leu Ser Val Gly Ile Glu 165 170 175 acc att gat gat atc atc gct gac ctc gaa ggc ggc ttt gct gca atc 576 Thr Ile Asp Asp Ile Ile Ala Asp Leu Glu Gly Gly Phe Ala Ala Ile 180 185 190 tagctttaaa tagactcacc cca 599 <210> 250 <211> 192 <212> PRT <213> Corynebacterium glutamicum <400> 250 Val Leu Pro Tyr Phe Val Thr Pro Asp Ala Ala Tyr His Gly Leu Lys 1 5 10 15 Tyr Ala Asp Leu Gly Ala Pro Ala Phe Gly Leu Lys Val Arg Val Gly 20 25 30 Leu Leu Arg Asp Thr Gly Ser Thr Leu Ser Ala Phe Asn Ala Trp Ala 35 40 45 Ala Val Gln Gly Ile Asp Thr Leu Ser Leu Arg Leu Glu Arg His Asn 50 55 60 Glu Asn Ala Ile Lys Val Ala Glu Phe Leu Asn Asn His Glu Lys Val 65 70 75 80 Glu Lys Val Asn Phe Ala Gly Leu Lys Asp Ser Pro Trp Tyr Ala Thr 85 90 95 Lys Glu Lys Leu Gly Leu Lys Tyr Thr Gly Ser Val Leu Thr Phe Glu 100 105 110 Ile Lys Gly Gly Lys Asp Glu Ala Trp Ala Phe Ile Asp Ala Leu Lys 115 120 125 Leu His Ser Asn Leu Ala Asn Ile Gly Asp Val Arg Ser Leu Val Val 130 135 140 His Pro Ala Thr Thr Thr His Ser Gln Ser Asp Glu Ala Gly Leu Ala 145 150 155 160 Arg Ala Gly Val Thr Gln Ser Thr Val Arg Leu Ser Val Gly Ile Glu 165 170 175 Thr Ile Asp Asp Ile Ile Ala Asp Leu Glu Gly Gly Phe Ala Ala Ile 180 185 190 <210> 251 <211> 613 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> RXS00405 <400> 251 agaataaatt tataccacac agtctattgc aatagaccaa gctgttcagt agggtgcatg 60 ggagaagaat ttcctaataa aaactcttaa ggacctccaa atg cca aag tac gac 115 Met Pro Lys Tyr Asp 1 5 aat tcc aat gct gac cag tgg ggc ttt gaa acc cgc tcc att cac gca 163 Asn Ser Asn Ala Asp Gln Trp Gly Phe Glu Thr Arg Ser Ile His Ala 10 15 20 ggc cag tca gta gac gca cag acc agc gca cga aac ctt ccg atc tac 211 Gly Gln Ser Val Asp Ala Gln Thr Ser Ala Arg Asn Leu Pro Ile Tyr 25 30 35 caa tcc acc gct ttc gtg ttc gac tcc gct gag cac gcc aag cag cgt 259 Gln Ser Thr Ala Phe Val Phe Asp Ser Ala Glu His Ala Lys Gln Arg 40 45 50 ttc gca ctt gag gat cta ggc cct gtt tac tcc cgc ctc acc aac cca 307 Phe Ala Leu Glu Asp Leu Gly Pro Val Tyr Ser Arg Leu Thr Asn Pro 55 60 65 acc gtt gag gct ttg gaa aac cgc atc gct tcc ctc gaa ggt ggc gtc 355 Thr Val Glu Ala Leu Glu Asn Arg Ile Ala Ser Leu Glu Gly Gly Val 70 75 80 85 cac gct gta gcg ttc tcc tcc gga cag gcc gca acc acc aac gcc att 403 His Ala Val Ala Phe Ser Ser Gly Gln Ala Ala Thr Thr Asn Ala Ile 90 95 100 ttg aac ctg gca gga gcg ggc gac cac atc gtc acc tcc cca cgc ctc 451 Leu Asn Leu Ala Gly Ala Gly Asp His Ile Val Thr Ser Pro Arg Leu 105 110 115 tac ggt ggc acc gag act cta ttc ctt atc act ctt aac cgc ctg ggt 499 Tyr Gly Gly Thr Glu Thr Leu Phe Leu Ile Thr Leu Asn Arg Leu Gly 120 125 130 atc gat gtt tcc ttc gtg gaa aac ccc gac gac cct gag tcc tgg cag 547 Ile Asp Val Ser Phe Val Glu Asn Pro Asp Asp Pro Glu Ser Trp Gln 135 140 145 gca gcc gtt cag cca aac acc aaa gca ttc ttc ggc gag act ttc gcc 595 Ala Ala Val Gln Pro Asn Thr Lys Ala Phe Phe Gly Glu Thr Phe Ala 150 155 160 165 aac cca cag gca gac gtc 613 Asn Pro Gln Ala Asp Val 170 <210> 252 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 252 Met Pro Lys Tyr Asp Asn Ser Asn Ala Asp Gln Trp Gly Phe Glu Thr 1 5 10 15 Arg Ser Ile His Ala Gly Gln Ser Val Asp Ala Gln Thr Ser Ala Arg 20 25 30 Asn Leu Pro Ile Tyr Gln Ser Thr Ala Phe Val Phe Asp Ser Ala Glu 35 40 45 His Ala Lys Gln Arg Phe Ala Leu Glu Asp Leu Gly Pro Val Tyr Ser 50 55 60 Arg Leu Thr Asn Pro Thr Val Glu Ala Leu Glu Asn Arg Ile Ala Ser 65 70 75 80 Leu Glu Gly Gly Val His Ala Val Ala Phe Ser Ser Gly Gln Ala Ala 85 90 95 Thr Thr Asn Ala Ile Leu Asn Leu Ala Gly Ala Gly Asp His Ile Val 100 105 110 Thr Ser Pro Arg Leu Tyr Gly Gly Thr Glu Thr Leu Phe Leu Ile Thr 115 120 125 Leu Asn Arg Leu Gly Ile Asp Val Ser Phe Val Glu Asn Pro Asp Asp 130 135 140 Pro Glu Ser Trp Gln Ala Ala Val Gln Pro Asn Thr Lys Ala Phe Phe 145 150 155 160 Gly Glu Thr Phe Ala Asn Pro Gln Ala Asp Val 165 170 <210> 253 <211> 1812 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1789) <223> RXC00164 <400> 253 ctgctttgcg ggaggttatg aaatgagtgg ggagacgtcg aaaagcatgc gctttccgtt 60 ggccagcctg ccgcaagtgc ggcgcgaggt ggcccggcag gtg ggt cgt att ccg 115 Val Gly Arg Ile Pro 1 5 cgg gcg aag tgg tgg ttt tta ggc gcg ctg gtg ttg ctg agt gcg ggc 163 Arg Ala Lys Trp Trp Phe Leu Gly Ala Leu Val Leu Leu Ser Ala Gly 10 15 20 gct tat gcg tcg gtg ctg gtg ccg cag gtg ctg ggg cgg att gtg gat 211 Ala Tyr Ala Ser Val Leu Val Pro Gln Val Leu Gly Arg Ile Val Asp 25 30 35 ctg gtg tcc gat ggc gcg cag atg cgt gat ttt gtt gag ctc agt gtg 259 Leu Val Ser Asp Gly Ala Gln Met Arg Asp Phe Val Glu Leu Ser Val 40 45 50 att ctc att gcg gtg gca att gcc ggc gcg gtg ctc agt gcg tgc ggg 307 Ile Leu Ile Ala Val Ala Ile Ala Gly Ala Val Leu Ser Ala Cys Gly 55 60 65 ttc tat gtg gtg tcg cgg att tct gag aag att atc gcc aat ttg agg 355 Phe Tyr Val Val Ser Arg Ile Ser Glu Lys Ile Ile Ala Asn Leu Arg 70 75 80 85 gaa gat atg gtg ggc acc gcg ctt ggg ttg ccc acg cac cag gtg gaa 403 Glu Asp Met Val Gly Thr Ala Leu Gly Leu Pro Thr His Gln Val Glu 90 95 100 gat gcg ggc tct ggc gat ttg gtg agc cgc tcc acc gat gat gtc tcc 451 Asp Ala Gly Ser Gly Asp Leu Val Ser Arg Ser Thr Asp Asp Val Ser 105 110 115 gag cta tcc gca gcg gtg aca gag acc gtc ccg att tta agt tcc tca 499 Glu Leu Ser Ala Ala Val Thr Glu Thr Val Pro Ile Leu Ser Ser Ser 120 125 130 ctg ttt acc att gcc gcg acg atc att gcg ctg ttt tct ttg gac tgg 547 Leu Phe Thr Ile Ala Ala Thr Ile Ile Ala Leu Phe Ser Leu Asp Trp 135 140 145 caa ttt gtg ctc att cct gtc gtg gtg gcg ccg gtg tac tac ttc gcg 595 Gln Phe Val Leu Ile Pro Val Val Val Ala Pro Val Tyr Tyr Phe Ala 150 155 160 165 tcc aag cac tat ttg agc aag gcg ccg gat cgg tat gcg gca gaa cgc 643 Ser Lys His Tyr Leu Ser Lys Ala Pro Asp Arg Tyr Ala Ala Glu Arg 170 175 180 gcg gcg atg gcg gag cgt gcg cga aag gta ctt gag gct att cgc ggg 691 Ala Ala Met Ala Glu Arg Ala Arg Lys Val Leu Glu Ala Ile Arg Gly 185 190 195 cgt gca act gtg cgg gcg tat tcc atg gaa gat gcc atg cat aat cag 739 Arg Ala Thr Val Arg Ala Tyr Ser Met Glu Asp Ala Met His Asn Gln 200 205 210 att gat cag gcg tcg tgg tct gtg gtg gtc aag ggt att cgt gcg cgc 787 Ile Asp Gln Ala Ser Trp Ser Val Val Val Lys Gly Ile Arg Ala Arg 215 220 225 acc acc atg ttg att ttg aac atg tgg atg ctg ttt gcg gaa ttc ctc 835 Thr Thr Met Leu Ile Leu Asn Met Trp Met Leu Phe Ala Glu Phe Leu 230 235 240 245 atg ctc gcg gtc gcg ttg gtg atc ggc tac aag ctg gtc att gat aat 883 Met Leu Ala Val Ala Leu Val Ile Gly Tyr Lys Leu Val Ile Asp Asn 250 255 260 gcg ctg acg atc ggc gcg gtt acc ggt gcc gtg ctg atg att att cgt 931 Ala Leu Thr Ile Gly Ala Val Thr Gly Ala Val Leu Met Ile Ile Arg 265 270 275 ctg cgt ggc ccg atg aat atg ttc atg cgc gtg ctc gac acc att caa 979 Leu Arg Gly Pro Met Asn Met Phe Met Arg Val Leu Asp Thr Ile Gln 280 285 290 tcc ggc tat gcg tcg ctg gcg cgc atc gtg gga gtt gtt gcg gat ccg 1027 Ser Gly Tyr Ala Ser Leu Ala Arg Ile Val Gly Val Val Ala Asp Pro 295 300 305 ccg att cct gtg ccc gac agc ggt gtg aaa gca cct cag ggc aaa gtg 1075 Pro Ile Pro Val Pro Asp Ser Gly Val Lys Ala Pro Gln Gly Lys Val 310 315 320 325 gaa ttg cgc aac gtc agc ttt agc tat ggc gat tcc tgg gcg gtg aaa 1123 Glu Leu Arg Asn Val Ser Phe Ser Tyr Gly Asp Ser Trp Ala Val Lys 330 335 340 gac atc gac atc acg atc aat tcc ggc gaa act gtc gcg ctc gtg ggc 1171 Asp Ile Asp Ile Thr Ile Asn Ser Gly Glu Thr Val Ala Leu Val Gly 345 350 355 gca tct ggc gca ggt aag acg acg gtc gcc gcc ttg ctg gcg ggc ttg 1219 Ala Ser Gly Ala Gly Lys Thr Thr Val Ala Ala Leu Leu Ala Gly Leu 360 365 370 cgg gtg cca gat caa ggg caa gtg ctt gtc gac gac ttc ccc gtc tct 1267 Arg Val Pro Asp Gln Gly Gln Val Leu Val Asp Asp Phe Pro Val Ser 375 380 385 cac ctc tct gac cgc gag cgt atc gcc cgc ttg gcc atg gtc agc cag 1315 His Leu Ser Asp Arg Glu Arg Ile Ala Arg Leu Ala Met Val Ser Gln 390 395 400 405 gag gtt cat gtt ttc tcc ggc acg ctg cgc cag gat ctc acc ttg gct 1363 Glu Val His Val Phe Ser Gly Thr Leu Arg Gln Asp Leu Thr Leu Ala 410 415 420 aaa cca gat gcc tcc gat gag gaa tta gcg cat gct ctt ggg caa gtt 1411 Lys Pro Asp Ala Ser Asp Glu Glu Leu Ala His Ala Leu Gly Gln Val 425 430 435 aat gcc ctt gac tgg ttg gag agt ctt cca gaa gga ctg gac acg gtc 1459 Asn Ala Leu Asp Trp Leu Glu Ser Leu Pro Glu Gly Leu Asp Thr Val 440 445 450 gtt ggt gcg cga gga atc cag cta gaa cca gtg gtg gct cag cag ttg 1507 Val Gly Ala Arg Gly Ile Gln Leu Glu Pro Val Val Ala Gln Gln Leu 455 460 465 gcg ttg gcc cgg gtg ttg ttg ctc aat ccg gcg atc gtc atc atg gat 1555 Ala Leu Ala Arg Val Leu Leu Leu Asn Pro Ala Ile Val Ile Met Asp 470 475 480 485 gaa gcc acg gca gaa gca gga tcg gcg ggt gcc agc gca ctg gaa gag 1603 Glu Ala Thr Ala Glu Ala Gly Ser Ala Gly Ala Ser Ala Leu Glu Glu 490 495 500 gct gca gat gca gtg agc aag aac cgt tcc gca ttg gtg gtg gcg cac 1651 Ala Ala Asp Ala Val Ser Lys Asn Arg Ser Ala Leu Val Val Ala His 505 510 515 cgg ttg gat cag gca tcg cgg gct gat cag att ctg gtg atg gat aag 1699 Arg Leu Asp Gln Ala Ser Arg Ala Asp Gln Ile Leu Val Met Asp Lys 520 525 530 ggg gag gtt gtg gaa tcc ggt act cac cag gag tta ttg gat cac ggg 1747 Gly Glu Val Val Glu Ser Gly Thr His Gln Glu Leu Leu Asp His Gly 535 540 545 ggt att tat cag cgt ctg tgg act gcg tgg agt gtc gga aga 1789 Gly Ile Tyr Gln Arg Leu Trp Thr Ala Trp Ser Val Gly Arg 550 555 560 tagttgactg ttcaatgcgt tga 1812 <210> 254 <211> 563 <212> PRT <213> Corynebacterium glutamicum <400> 254 Val Gly Arg Ile Pro Arg Ala Lys Trp Trp Phe Leu Gly Ala Leu Val 1 5 10 15 Leu Leu Ser Ala Gly Ala Tyr Ala Ser Val Leu Val Pro Gln Val Leu 20 25 30 Gly Arg Ile Val Asp Leu Val Ser Asp Gly Ala Gln Met Arg Asp Phe 35 40 45 Val Glu Leu Ser Val Ile Leu Ile Ala Val Ala Ile Ala Gly Ala Val 50 55 60 Leu Ser Ala Cys Gly Phe Tyr Val Val Ser Arg Ile Ser Glu Lys Ile 65 70 75 80 Ile Ala Asn Leu Arg Glu Asp Met Val Gly Thr Ala Leu Gly Leu Pro 85 90 95 Thr His Gln Val Glu Asp Ala Gly Ser Gly Asp Leu Val Ser Arg Ser 100 105 110 Thr Asp Asp Val Ser Glu Leu Ser Ala Ala Val Thr Glu Thr Val Pro 115 120 125 Ile Leu Ser Ser Ser Leu Phe Thr Ile Ala Ala Thr Ile Ile Ala Leu 130 135 140 Phe Ser Leu Asp Trp Gln Phe Val Leu Ile Pro Val Val Val Ala Pro 145 150 155 160 Val Tyr Tyr Phe Ala Ser Lys His Tyr Leu Ser Lys Ala Pro Asp Arg 165 170 175 Tyr Ala Ala Glu Arg Ala Ala Met Ala Glu Arg Ala Arg Lys Val Leu 180 185 190 Glu Ala Ile Arg Gly Arg Ala Thr Val Arg Ala Tyr Ser Met Glu Asp 195 200 205 Ala Met His Asn Gln Ile Asp Gln Ala Ser Trp Ser Val Val Val Lys 210 215 220 Gly Ile Arg Ala Arg Thr Thr Met Leu Ile Leu Asn Met Trp Met Leu 225 230 235 240 Phe Ala Glu Phe Leu Met Leu Ala Val Ala Leu Val Ile Gly Tyr Lys 245 250 255 Leu Val Ile Asp Asn Ala Leu Thr Ile Gly Ala Val Thr Gly Ala Val 260 265 270 Leu Met Ile Ile Arg Leu Arg Gly Pro Met Asn Met Phe Met Arg Val 275 280 285 Leu Asp Thr Ile Gln Ser Gly Tyr Ala Ser Leu Ala Arg Ile Val Gly 290 295 300 Val Val Ala Asp Pro Pro Ile Pro Val Pro Asp Ser Gly Val Lys Ala 305 310 315 320 Pro Gln Gly Lys Val Glu Leu Arg Asn Val Ser Phe Ser Tyr Gly Asp 325 330 335 Ser Trp Ala Val Lys Asp Ile Asp Ile Thr Ile Asn Ser Gly Glu Thr 340 345 350 Val Ala Leu Val Gly Ala Ser Gly Ala Gly Lys Thr Thr Val Ala Ala 355 360 365 Leu Leu Ala Gly Leu Arg Val Pro Asp Gln Gly Gln Val Leu Val Asp 370 375 380 Asp Phe Pro Val Ser His Leu Ser Asp Arg Glu Arg Ile Ala Arg Leu 385 390 395 400 Ala Met Val Ser Gln Glu Val His Val Phe Ser Gly Thr Leu Arg Gln 405 410 415 Asp Leu Thr Leu Ala Lys Pro Asp Ala Ser Asp Glu Glu Leu Ala His 420 425 430 Ala Leu Gly Gln Val Asn Ala Leu Asp Trp Leu Glu Ser Leu Pro Glu 435 440 445 Gly Leu Asp Thr Val Val Gly Ala Arg Gly Ile Gln Leu Glu Pro Val 450 455 460 Val Ala Gln Gln Leu Ala Leu Ala Arg Val Leu Leu Leu Asn Pro Ala 465 470 475 480 Ile Val Ile Met Asp Glu Ala Thr Ala Glu Ala Gly Ser Ala Gly Ala 485 490 495 Ser Ala Leu Glu Glu Ala Ala Asp Ala Val Ser Lys Asn Arg Ser Ala 500 505 510 Leu Val Val Ala His Arg Leu Asp Gln Ala Ser Arg Ala Asp Gln Ile 515 520 525 Leu Val Met Asp Lys Gly Glu Val Val Glu Ser Gly Thr His Gln Glu 530 535 540 Leu Leu Asp His Gly Gly Ile Tyr Gln Arg Leu Trp Thr Ala Trp Ser 545 550 555 560 Val Gly Arg <210> 255 <211> 1713 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1690) <223> RXC01191 <400> 255 cgctgctttc acgcaactga aaccgcaccg gatcaagtta tttggggttg ttctttgtgg 60 cgtgttggtg gccgtcgcgg ggttggtagg gccctgggcg gtg ggt gga ctc gtc 115 Val Gly Gly Leu Val 1 5 gat aag ctc ctt gca acc ccg agc atg cgc gac gtt gta gtg ttc gcg 163 Asp Lys Leu Leu Ala Thr Pro Ser Met Arg Asp Val Val Val Phe Ala 10 15 20 ctg ctt atc gtg gct ggc ggc gtt gtt tcg agc ctg ggc acg tgg tgg 211 Leu Leu Ile Val Ala Gly Gly Val Val Ser Ser Leu Gly Thr Trp Trp 25 30 35 ggc agc gcg ctg atg gcg cgc gcg ttg gag ccg gcg atc gcg ggg ctg 259 Gly Ser Ala Leu Met Ala Arg Ala Leu Glu Pro Ala Ile Ala Gly Leu 40 45 50 cgc gag gat gtg ttg cgc gcg gcg gtg agt ttg gat gcg aac acg att 307 Arg Glu Asp Val Leu Arg Ala Ala Val Ser Leu Asp Ala Asn Thr Ile 55 60 65 gaa acg gcg ggg cgc ggc gac gtg att tcg cgt atc gcg gat gat tcg 355 Glu Thr Ala Gly Arg Gly Asp Val Ile Ser Arg Ile Ala Asp Asp Ser 70 75 80 85 cgg gag gtg tcc act gcg gcg agc acc gtg gtg ccg ctg atg gtg cag 403 Arg Glu Val Ser Thr Ala Ala Ser Thr Val Val Pro Leu Met Val Gln 90 95 100 gcg ggc ttt acc gtg gtg att tcc gcg ttt ggc atg gcg gcg gtt gat 451 Ala Gly Phe Thr Val Val Ile Ser Ala Phe Gly Met Ala Ala Val Asp 105 110 115 tgg cgc ctc ggc ctt gtc ggt ttg gtc gcg atc ccg ctg tat tgg acc 499 Trp Arg Leu Gly Leu Val Gly Leu Val Ala Ile Pro Leu Tyr Trp Thr 120 125 130 acg ttg cgc gtc tat tta ccc cgc tca ggt ccg ctt tat acg cgt gag 547 Thr Leu Arg Val Tyr Leu Pro Arg Ser Gly Pro Leu Tyr Thr Arg Glu 135 140 145 cgc gag gcc ttt ggg gtg cgc acg cag cgg ctt gtc ggc gca gtc gaa 595 Arg Glu Ala Phe Gly Val Arg Thr Gln Arg Leu Val Gly Ala Val Glu 150 155 160 165 ggc gcg gaa acc ttg cgc gct ttc cgc gca gaa gat aca gaa tta aag 643 Gly Ala Glu Thr Leu Arg Ala Phe Arg Ala Glu Asp Thr Glu Leu Lys 170 175 180 cgt atc gac gca gcc tcc ggc gaa gcc cgc gac att tcc att tct gtt 691 Arg Ile Asp Ala Ala Ser Gly Glu Ala Arg Asp Ile Ser Ile Ser Val 185 190 195 ttc agg ttc ctc aca tgg gca ttt tcc cgc aac aac cgc gcg gaa tgc 739 Phe Arg Phe Leu Thr Trp Ala Phe Ser Arg Asn Asn Arg Ala Glu Cys 200 205 210 atc acc ctc gtg ctc atc ttg ggc acc ggc ttt tac ctg gtc aac atc 787 Ile Thr Leu Val Leu Ile Leu Gly Thr Gly Phe Tyr Leu Val Asn Ile 215 220 225 gat ctg gtc acc gtc ggc gca gtc tca acc gcc gca ctg atc ttc cac 835 Asp Leu Val Thr Val Gly Ala Val Ser Thr Ala Ala Leu Ile Phe His 230 235 240 245 cga ctc ttc ggt cca atc ggc acg ctc gtg ggc atg ttc tcc gac atc 883 Arg Leu Phe Gly Pro Ile Gly Thr Leu Val Gly Met Phe Ser Asp Ile 250 255 260 caa tcc gcc agc gca tcg ctg atc cgc atg gtg ggc gtt att aac gcg 931 Gln Ser Ala Ser Ala Ser Leu Ile Arg Met Val Gly Val Ile Asn Ala 265 270 275 gca tcg aac cag gtc agc ggc acc tcg ccg gcg tct gcc agc acc gct 979 Ala Ser Asn Gln Val Ser Gly Thr Ser Pro Ala Ser Ala Ser Thr Ala 280 285 290 tta acg ctt ttc gac gtc tcc cac cac tat cac act gca ccc gtc atc 1027 Leu Thr Leu Phe Asp Val Ser His His Tyr His Thr Ala Pro Val Ile 295 300 305 aag aat gca tcc gtg cag ctg gaa cca ggg gaa cac atc gcc att gtg 1075 Lys Asn Ala Ser Val Gln Leu Glu Pro Gly Glu His Ile Ala Ile Val 310 315 320 325 ggt gcg acc ggc gct ggt aaa agc acg ctc gcc ctc att gcg gca ggc 1123 Gly Ala Thr Gly Ala Gly Lys Ser Thr Leu Ala Leu Ile Ala Ala Gly 330 335 340 ctg ctc agc cca act tcc ggg cag gtg gct ctc ggc gga tcg agt ttt 1171 Leu Leu Ser Pro Thr Ser Gly Gln Val Ala Leu Gly Gly Ser Ser Phe 345 350 355 tct aac gtc gaa ccg gaa gca ttg cgc cag aag atc gcg atg gtc agc 1219 Ser Asn Val Glu Pro Glu Ala Leu Arg Gln Lys Ile Ala Met Val Ser 360 365 370 caa gaa atc cac tgc ttc cga gga tct gtt tta gat aat ctt cgt atc 1267 Gln Glu Ile His Cys Phe Arg Gly Ser Val Leu Asp Asn Leu Arg Ile 375 380 385 gca cgc ccc gaa gcc acc gat gcg gac atc cac gcc gtt ctc gcc gat 1315 Ala Arg Pro Glu Ala Thr Asp Ala Asp Ile His Ala Val Leu Ala Asp 390 395 400 405 att ggt gat tcc tgg ttg gag cgc tta ccg caa ggc ata gac acc atc 1363 Ile Gly Asp Ser Trp Leu Glu Arg Leu Pro Gln Gly Ile Asp Thr Ile 410 415 420 gtg ggt gat ggc gct ttc cgt tta acc tct gtg gaa aac cag atc atg 1411 Val Gly Asp Gly Ala Phe Arg Leu Thr Ser Val Glu Asn Gln Ile Met 425 430 435 gcg ctt gct cgc gta cat ttg gcc gac cta gca atc gtc atc ctt gat 1459 Ala Leu Ala Arg Val His Leu Ala Asp Leu Ala Ile Val Ile Leu Asp 440 445 450 gaa gca acg gct gaa tca ggc tct gat cat gca aaa cag ctt gaa gat 1507 Glu Ala Thr Ala Glu Ser Gly Ser Asp His Ala Lys Gln Leu Glu Asp 455 460 465 gca gcc ctt aaa gtc act gaa aac aga tca gcc atc atc gtg gct cac 1555 Ala Ala Leu Lys Val Thr Glu Asn Arg Ser Ala Ile Ile Val Ala His 470 475 480 485 cgc ctc aac caa gcg aaa acc gcc gat cgc atc atc gtc atg gac tcc 1603 Arg Leu Asn Gln Ala Lys Thr Ala Asp Arg Ile Ile Val Met Asp Ser 490 495 500 gga gaa atc ata gaa tct gga acc cat gaa gag ctt cga gcg atc ggc 1651 Gly Glu Ile Ile Glu Ser Gly Thr His Glu Glu Leu Arg Ala Ile Gly 505 510 515 ggc cga tat gaa caa ctg tgg act gcg tgg tct gcg cgc taattagcca 1700 Gly Arg Tyr Glu Gln Leu Trp Thr Ala Trp Ser Ala Arg 520 525 530 cccaagacca cgc 1713 <210> 256 <211> 530 <212> PRT <213> Corynebacterium glutamicum <400> 256 Val Gly Gly Leu Val Asp Lys Leu Leu Ala Thr Pro Ser Met Arg Asp 1 5 10 15 Val Val Val Phe Ala Leu Leu Ile Val Ala Gly Gly Val Val Ser Ser 20 25 30 Leu Gly Thr Trp Trp Gly Ser Ala Leu Met Ala Arg Ala Leu Glu Pro 35 40 45 Ala Ile Ala Gly Leu Arg Glu Asp Val Leu Arg Ala Ala Val Ser Leu 50 55 60 Asp Ala Asn Thr Ile Glu Thr Ala Gly Arg Gly Asp Val Ile Ser Arg 65 70 75 80 Ile Ala Asp Asp Ser Arg Glu Val Ser Thr Ala Ala Ser Thr Val Val 85 90 95 Pro Leu Met Val Gln Ala Gly Phe Thr Val Val Ile Ser Ala Phe Gly 100 105 110 Met Ala Ala Val Asp Trp Arg Leu Gly Leu Val Gly Leu Val Ala Ile 115 120 125 Pro Leu Tyr Trp Thr Thr Leu Arg Val Tyr Leu Pro Arg Ser Gly Pro 130 135 140 Leu Tyr Thr Arg Glu Arg Glu Ala Phe Gly Val Arg Thr Gln Arg Leu 145 150 155 160 Val Gly Ala Val Glu Gly Ala Glu Thr Leu Arg Ala Phe Arg Ala Glu 165 170 175 Asp Thr Glu Leu Lys Arg Ile Asp Ala Ala Ser Gly Glu Ala Arg Asp 180 185 190 Ile Ser Ile Ser Val Phe Arg Phe Leu Thr Trp Ala Phe Ser Arg Asn 195 200 205 Asn Arg Ala Glu Cys Ile Thr Leu Val Leu Ile Leu Gly Thr Gly Phe 210 215 220 Tyr Leu Val Asn Ile Asp Leu Val Thr Val Gly Ala Val Ser Thr Ala 225 230 235 240 Ala Leu Ile Phe His Arg Leu Phe Gly Pro Ile Gly Thr Leu Val Gly 245 250 255 Met Phe Ser Asp Ile Gln Ser Ala Ser Ala Ser Leu Ile Arg Met Val 260 265 270 Gly Val Ile Asn Ala Ala Ser Asn Gln Val Ser Gly Thr Ser Pro Ala 275 280 285 Ser Ala Ser Thr Ala Leu Thr Leu Phe Asp Val Ser His His Tyr His 290 295 300 Thr Ala Pro Val Ile Lys Asn Ala Ser Val Gln Leu Glu Pro Gly Glu 305 310 315 320 His Ile Ala Ile Val Gly Ala Thr Gly Ala Gly Lys Ser Thr Leu Ala 325 330 335 Leu Ile Ala Ala Gly Leu Leu Ser Pro Thr Ser Gly Gln Val Ala Leu 340 345 350 Gly Gly Ser Ser Phe Ser Asn Val Glu Pro Glu Ala Leu Arg Gln Lys 355 360 365 Ile Ala Met Val Ser Gln Glu Ile His Cys Phe Arg Gly Ser Val Leu 370 375 380 Asp Asn Leu Arg Ile Ala Arg Pro Glu Ala Thr Asp Ala Asp Ile His 385 390 395 400 Ala Val Leu Ala Asp Ile Gly Asp Ser Trp Leu Glu Arg Leu Pro Gln 405 410 415 Gly Ile Asp Thr Ile Val Gly Asp Gly Ala Phe Arg Leu Thr Ser Val 420 425 430 Glu Asn Gln Ile Met Ala Leu Ala Arg Val His Leu Ala Asp Leu Ala 435 440 445 Ile Val Ile Leu Asp Glu Ala Thr Ala Glu Ser Gly Ser Asp His Ala 450 455 460 Lys Gln Leu Glu Asp Ala Ala Leu Lys Val Thr Glu Asn Arg Ser Ala 465 470 475 480 Ile Ile Val Ala His Arg Leu Asn Gln Ala Lys Thr Ala Asp Arg Ile 485 490 495 Ile Val Met Asp Ser Gly Glu Ile Ile Glu Ser Gly Thr His Glu Glu 500 505 510 Leu Arg Ala Ile Gly Gly Arg Tyr Glu Gln Leu Trp Thr Ala Trp Ser 515 520 525 Ala Arg 530 <210> 257 <211> 1392 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1369) <223> RXA02646 <400> 257 ttggaaataa aacctatgcc aaagtaggtg caattctagg agaagattac actagtcaac 60 catgagtgaa acatacgtgt ctgagaaaag tccaggagtg atg gct agc gga gcg 115 Met Ala Ser Gly Ala 1 5 gag ctg att cgt gcc gcc gac att caa acg gcg cag gca cga att tcc 163 Glu Leu Ile Arg Ala Ala Asp Ile Gln Thr Ala Gln Ala Arg Ile Ser 10 15 20 tcc gtc att gca cca act cca ttg cag tat tgc cct cgt ctt tct gag 211 Ser Val Ile Ala Pro Thr Pro Leu Gln Tyr Cys Pro Arg Leu Ser Glu 25 30 35 gaa acc gga gcg gaa atc tac ctt aag cgt gag gat ctg cag gat gtt 259 Glu Thr Gly Ala Glu Ile Tyr Leu Lys Arg Glu Asp Leu Gln Asp Val 40 45 50 cgt tcc tac aag atc cgc ggt gcg ctg aac tct gga gcg cag ctc acc 307 Arg Ser Tyr Lys Ile Arg Gly Ala Leu Asn Ser Gly Ala Gln Leu Thr 55 60 65 caa gag cag cgc gat gca ggt atc gtt gcc gca tct gca ggt aac cat 355 Gln Glu Gln Arg Asp Ala Gly Ile Val Ala Ala Ser Ala Gly Asn His 70 75 80 85 gcc cag ggc gtg gcc tat gtg tgc aag tcc ttg ggc gtt cag gga cgc 403 Ala Gln Gly Val Ala Tyr Val Cys Lys Ser Leu Gly Val Gln Gly Arg 90 95 100 atc tat gtt cct gtg cag act cca aag caa aag cgt gac cgc atc atg 451 Ile Tyr Val Pro Val Gln Thr Pro Lys Gln Lys Arg Asp Arg Ile Met 105 110 115 gtt cac ggc gga gag ttt gtc tcc ttg gtg gtc act ggc aat aac ttc 499 Val His Gly Gly Glu Phe Val Ser Leu Val Val Thr Gly Asn Asn Phe 120 125 130 gac gaa gca tcg gct gca gcg cat gaa gat gca gag cgc acc ggc gca 547 Asp Glu Ala Ser Ala Ala Ala His Glu Asp Ala Glu Arg Thr Gly Ala 135 140 145 acg ctg atc gag cct ttc gat gct cgc aac acc gtc atc ggt cag ggc 595 Thr Leu Ile Glu Pro Phe Asp Ala Arg Asn Thr Val Ile Gly Gln Gly 150 155 160 165 acc gtg gct gct gag atc ttg tcg cag ctg act tcc atg ggc aag agt 643 Thr Val Ala Ala Glu Ile Leu Ser Gln Leu Thr Ser Met Gly Lys Ser 170 175 180 gca gat cac gtg atg gtt cca gtc ggc ggt ggc gga ctt ctt gca ggt 691 Ala Asp His Val Met Val Pro Val Gly Gly Gly Gly Leu Leu Ala Gly 185 190 195 gtg gtc agc tac atg gct gat atg gca cct cgc act gcg atc gtt ggt 739 Val Val Ser Tyr Met Ala Asp Met Ala Pro Arg Thr Ala Ile Val Gly 200 205 210 atc gaa cca gcg gga gca gca tcc atg cag gct gca ttg cac aat ggt 787 Ile Glu Pro Ala Gly Ala Ala Ser Met Gln Ala Ala Leu His Asn Gly 215 220 225 gga cca atc act ttg gag act gtt gat ccc ttt gtg gac ggc gca gca 835 Gly Pro Ile Thr Leu Glu Thr Val Asp Pro Phe Val Asp Gly Ala Ala 230 235 240 245 gtc aaa cgt gtc gga gat ctc aac tac acc atc gtg gag aag aac cag 883 Val Lys Arg Val Gly Asp Leu Asn Tyr Thr Ile Val Glu Lys Asn Gln 250 255 260 ggt cgc gtg cac atg atg agc gcg acc gag ggc gct gtg tgt act gag 931 Gly Arg Val His Met Met Ser Ala Thr Glu Gly Ala Val Cys Thr Glu 265 270 275 atg ctc gat ctt tac caa aac gaa ggc atc atc gcg gag cct gct ggc 979 Met Leu Asp Leu Tyr Gln Asn Glu Gly Ile Ile Ala Glu Pro Ala Gly 280 285 290 gcg ctg tct atc gct ggg ttg aag gaa atg tcc ttt gca gct cgc tct 1027 Ala Leu Ser Ile Ala Gly Leu Lys Glu Met Ser Phe Ala Ala Arg Ser 295 300 305 gtc gtg gtg tgc atc atc tct ggt ggc aac aac gat gtg ctg cgt tat 1075 Val Val Val Cys Ile Ile Ser Gly Gly Asn Asn Asp Val Leu Arg Tyr 310 315 320 325 gcg gaa atc gct gag cgc tcc ttg gtg cgc cgc ggt tta aag cac tac 1123 Ala Glu Ile Ala Glu Arg Ser Leu Val Arg Arg Gly Leu Lys His Tyr 330 335 340 ttc ttg gtg aac ttc ccg caa aag cct ggt cag ttg cgt cac ttc ctg 1171 Phe Leu Val Asn Phe Pro Gln Lys Pro Gly Gln Leu Arg His Phe Leu 345 350 355 gaa gat atc ctg gga ccg gat gat gac atc acg ctg ttt gag tac ctc 1219 Glu Asp Ile Leu Gly Pro Asp Asp Asp Ile Thr Leu Phe Glu Tyr Leu 360 365 370 aag cgc aac aac cgt gag acc ggt act gcg ttg gtg ggt att cac ttg 1267 Lys Arg Asn Asn Arg Glu Thr Gly Thr Ala Leu Val Gly Ile His Leu 375 380 385 agt gaa gca tca gga ttg gat tct ttg ctg gaa cgt atg gag gaa tcg 1315 Ser Glu Ala Ser Gly Leu Asp Ser Leu Leu Glu Arg Met Glu Glu Ser 390 395 400 405 gca att gat tcc cgt cgc ctc gag ccg ggc acc cct gag tac gaa tac 1363 Ala Ile Asp Ser Arg Arg Leu Glu Pro Gly Thr Pro Glu Tyr Glu Tyr 410 415 420 ttg acc taaacatagc tgaaggccac ctc 1392 Leu Thr <210> 258 <211> 423 <212> PRT <213> Corynebacterium glutamicum <400> 258 Met Ala Ser Gly Ala Glu Leu Ile Arg Ala Ala Asp Ile Gln Thr Ala 1 5 10 15 Gln Ala Arg Ile Ser Ser Val Ile Ala Pro Thr Pro Leu Gln Tyr Cys 20 25 30 Pro Arg Leu Ser Glu Glu Thr Gly Ala Glu Ile Tyr Leu Lys Arg Glu 35 40 45 Asp Leu Gln Asp Val Arg Ser Tyr Lys Ile Arg Gly Ala Leu Asn Ser 50 55 60 Gly Ala Gln Leu Thr Gln Glu Gln Arg Asp Ala Gly Ile Val Ala Ala 65 70 75 80 Ser Ala Gly Asn His Ala Gln Gly Val Ala Tyr Val Cys Lys Ser Leu 85 90 95 Gly Val Gln Gly Arg Ile Tyr Val Pro Val Gln Thr Pro Lys Gln Lys 100 105 110 Arg Asp Arg Ile Met Val His Gly Gly Glu Phe Val Ser Leu Val Val 115 120 125 Thr Gly Asn Asn Phe Asp Glu Ala Ser Ala Ala Ala His Glu Asp Ala 130 135 140 Glu Arg Thr Gly Ala Thr Leu Ile Glu Pro Phe Asp Ala Arg Asn Thr 145 150 155 160 Val Ile Gly Gln Gly Thr Val Ala Ala Glu Ile Leu Ser Gln Leu Thr 165 170 175 Ser Met Gly Lys Ser Ala Asp His Val Met Val Pro Val Gly Gly Gly 180 185 190 Gly Leu Leu Ala Gly Val Val Ser Tyr Met Ala Asp Met Ala Pro Arg 195 200 205 Thr Ala Ile Val Gly Ile Glu Pro Ala Gly Ala Ala Ser Met Gln Ala 210 215 220 Ala Leu His Asn Gly Gly Pro Ile Thr Leu Glu Thr Val Asp Pro Phe 225 230 235 240 Val Asp Gly Ala Ala Val Lys Arg Val Gly Asp Leu Asn Tyr Thr Ile 245 250 255 Val Glu Lys Asn Gln Gly Arg Val His Met Met Ser Ala Thr Glu Gly 260 265 270 Ala Val Cys Thr Glu Met Leu Asp Leu Tyr Gln Asn Glu Gly Ile Ile 275 280 285 Ala Glu Pro Ala Gly Ala Leu Ser Ile Ala Gly Leu Lys Glu Met Ser 290 295 300 Phe Ala Ala Arg Ser Val Val Val Cys Ile Ile Ser Gly Gly Asn Asn 305 310 315 320 Asp Val Leu Arg Tyr Ala Glu Ile Ala Glu Arg Ser Leu Val Arg Arg 325 330 335 Gly Leu Lys His Tyr Phe Leu Val Asn Phe Pro Gln Lys Pro Gly Gln 340 345 350 Leu Arg His Phe Leu Glu Asp Ile Leu Gly Pro Asp Asp Asp Ile Thr 355 360 365 Leu Phe Glu Tyr Leu Lys Arg Asn Asn Arg Glu Thr Gly Thr Ala Leu 370 375 380 Val Gly Ile His Leu Ser Glu Ala Ser Gly Leu Asp Ser Leu Leu Glu 385 390 395 400 Arg Met Glu Glu Ser Ala Ile Asp Ser Arg Arg Leu Glu Pro Gly Thr 405 410 415 Pro Glu Tyr Glu Tyr Leu Thr 420 <210> 259 <211> 966 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(943) <223> RXA00766 <400> 259 tatggcgctt gaaccacaaa taaagtctgc accgacgccg gtgatcttaa ttgtcgaacc 60 ctacggcggg tccatccggc aacaaaaccc caacctacca atg gtt ttt tgg gac 115 Met Val Phe Trp Asp 1 5 gat gca gcc tta acc cga ggc gat ggc atc ttt gaa aca ctc ctc atc 163 Asp Ala Ala Leu Thr Arg Gly Asp Gly Ile Phe Glu Thr Leu Leu Ile 10 15 20 cgc gac gga cat gcc tgc aac gtg cgc cga cac gga gaa cgc ttc aaa 211 Arg Asp Gly His Ala Cys Asn Val Arg Arg His Gly Glu Arg Phe Lys 25 30 35 gca tcg gca gca cta ttg gga ctg cca gag ccg atc ctg gaa gac tgg 259 Ala Ser Ala Ala Leu Leu Gly Leu Pro Glu Pro Ile Leu Glu Asp Trp 40 45 50 gaa aaa gcc acc caa atg ggc atc gaa tcc tgg tac tcc cac ccc aac 307 Glu Lys Ala Thr Gln Met Gly Ile Glu Ser Trp Tyr Ser His Pro Asn 55 60 65 gca ggc gag gcc tca tgc acc tgg acg ctc agc cga ggt cgt tcc tcc 355 Ala Gly Glu Ala Ser Cys Thr Trp Thr Leu Ser Arg Gly Arg Ser Ser 70 75 80 85 acg ggg ctg gcc tca gga tgg tta acc atc acc cca gtc tcc tcc gac 403 Thr Gly Leu Ala Ser Gly Trp Leu Thr Ile Thr Pro Val Ser Ser Asp 90 95 100 aaa ctg gcg caa cgt gaa cac ggt gta tcg gtc atg acc agt tca aga 451 Lys Leu Ala Gln Arg Glu His Gly Val Ser Val Met Thr Ser Ser Arg 105 110 115 gga tat tcc atc gac acc ggc ctc ccc gga atc gga aaa gcc acc cga 499 Gly Tyr Ser Ile Asp Thr Gly Leu Pro Gly Ile Gly Lys Ala Thr Arg 120 125 130 ggc gag cta tct aaa gtg gaa cga acc ccc gca cca tgg ctg aca gtc 547 Gly Glu Leu Ser Lys Val Glu Arg Thr Pro Ala Pro Trp Leu Thr Val 135 140 145 ggc gcc aaa aca cta gcc tac gca gca aac atg gca gcc ctg cgc tac 595 Gly Ala Lys Thr Leu Ala Tyr Ala Ala Asn Met Ala Ala Leu Arg Tyr 150 155 160 165 gcc aaa tca aac gga ttc gac gat gtg atc ttc acc gat ggc gac cgc 643 Ala Lys Ser Asn Gly Phe Asp Asp Val Ile Phe Thr Asp Gly Asp Arg 170 175 180 gtt cta gaa ggc gcc acc tcc acc gta gtg agt ttc aaa ggc gac aaa 691 Val Leu Glu Gly Ala Thr Ser Thr Val Val Ser Phe Lys Gly Asp Lys 185 190 195 atc cgc acc cct tca ccc ggt ggc gac att ctc ccc gga acc acc caa 739 Ile Arg Thr Pro Ser Pro Gly Gly Asp Ile Leu Pro Gly Thr Thr Gln 200 205 210 gca gca ctc ttt gca cac gca acc gaa aaa gga tgg cga tgt aaa gaa 787 Ala Ala Leu Phe Ala His Ala Thr Glu Lys Gly Trp Arg Cys Lys Glu 215 220 225 aaa gac tta agc att gac gat ctt ttc gga gcc gac agc gtg tgg cta 835 Lys Asp Leu Ser Ile Asp Asp Leu Phe Gly Ala Asp Ser Val Trp Leu 230 235 240 245 gtg tcc tcc gtc cgc gga cca gtt cgg gtg acc agg ctc gat gga cac 883 Val Ser Ser Val Arg Gly Pro Val Arg Val Thr Arg Leu Asp Gly His 250 255 260 aaa tta cgg aaa cca gac aat gaa aaa gaa atc aag gcg ctg att acc 931 Lys Leu Arg Lys Pro Asp Asn Glu Lys Glu Ile Lys Ala Leu Ile Thr 265 270 275 aaa gct ctg ggg tagaggctgg cgctgggact tgc 966 Lys Ala Leu Gly 280 <210> 260 <211> 281 <212> PRT <213> Corynebacterium glutamicum <400> 260 Met Val Phe Trp Asp Asp Ala Ala Leu Thr Arg Gly Asp Gly Ile Phe 1 5 10 15 Glu Thr Leu Leu Ile Arg Asp Gly His Ala Cys Asn Val Arg Arg His 20 25 30 Gly Glu Arg Phe Lys Ala Ser Ala Ala Leu Leu Gly Leu Pro Glu Pro 35 40 45 Ile Leu Glu Asp Trp Glu Lys Ala Thr Gln Met Gly Ile Glu Ser Trp 50 55 60 Tyr Ser His Pro Asn Ala Gly Glu Ala Ser Cys Thr Trp Thr Leu Ser 65 70 75 80 Arg Gly Arg Ser Ser Thr Gly Leu Ala Ser Gly Trp Leu Thr Ile Thr 85 90 95 Pro Val Ser Ser Asp Lys Leu Ala Gln Arg Glu His Gly Val Ser Val 100 105 110 Met Thr Ser Ser Arg Gly Tyr Ser Ile Asp Thr Gly Leu Pro Gly Ile 115 120 125 Gly Lys Ala Thr Arg Gly Glu Leu Ser Lys Val Glu Arg Thr Pro Ala 130 135 140 Pro Trp Leu Thr Val Gly Ala Lys Thr Leu Ala Tyr Ala Ala Asn Met 145 150 155 160 Ala Ala Leu Arg Tyr Ala Lys Ser Asn Gly Phe Asp Asp Val Ile Phe 165 170 175 Thr Asp Gly Asp Arg Val Leu Glu Gly Ala Thr Ser Thr Val Val Ser 180 185 190 Phe Lys Gly Asp Lys Ile Arg Thr Pro Ser Pro Gly Gly Asp Ile Leu 195 200 205 Pro Gly Thr Thr Gln Ala Ala Leu Phe Ala His Ala Thr Glu Lys Gly 210 215 220 Trp Arg Cys Lys Glu Lys Asp Leu Ser Ile Asp Asp Leu Phe Gly Ala 225 230 235 240 Asp Ser Val Trp Leu Val Ser Ser Val Arg Gly Pro Val Arg Val Thr 245 250 255 Arg Leu Asp Gly His Lys Leu Arg Lys Pro Asp Asn Glu Lys Glu Ile 260 265 270 Lys Ala Leu Ile Thr Lys Ala Leu Gly 275 280 <210> 261 <211> 1224 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1201) <223> RXN01690 <400> 261 cctagccatt cctcaaaacc gtgagacgaa attggctatt catcccataa aatggggctg 60 actagtgtat ctgtcaggta gcaggtgtac cttaaaatcc atg acg tca tta gag 115 Met Thr Ser Leu Glu 1 5 ttc aca gta acc cgt acc gaa aat ccg acg tca ccc gat cgt ctg aag 163 Phe Thr Val Thr Arg Thr Glu Asn Pro Thr Ser Pro Asp Arg Leu Lys 10 15 20 gaa att ctt gcc gca ccg aag ttc ggt aag ttc ttc acc gac cac atg 211 Glu Ile Leu Ala Ala Pro Lys Phe Gly Lys Phe Phe Thr Asp His Met 25 30 35 gtg acc att gac tgg aac gag tcg gaa ggc tgg cac aac gcc caa tta 259 Val Thr Ile Asp Trp Asn Glu Ser Glu Gly Trp His Asn Ala Gln Leu 40 45 50 gtg cca tac gcg ccg att cct atg gat cct gcc acc acc gta ttc cac 307 Val Pro Tyr Ala Pro Ile Pro Met Asp Pro Ala Thr Thr Val Phe His 55 60 65 tac gga cag gca att ttt gag gga att aag gcc tac cgc cat tcg gac 355 Tyr Gly Gln Ala Ile Phe Glu Gly Ile Lys Ala Tyr Arg His Ser Asp 70 75 80 85 gaa acc atc aag act ttc cgt cct gat gaa aac gcc gag cgt atg cag 403 Glu Thr Ile Lys Thr Phe Arg Pro Asp Glu Asn Ala Glu Arg Met Gln 90 95 100 cgt tca gca gct cga atg gca atg cca cag ttg cca acc gag gac ttt 451 Arg Ser Ala Ala Arg Met Ala Met Pro Gln Leu Pro Thr Glu Asp Phe 105 110 115 att aaa gca ctt gaa ctg ctg gta gac gcg gat cag gat tgg gtt cct 499 Ile Lys Ala Leu Glu Leu Leu Val Asp Ala Asp Gln Asp Trp Val Pro 120 125 130 gag tac ggc gga gaa gct tcc ctc tac ctg cgc cca ttc atg atc tcc 547 Glu Tyr Gly Gly Glu Ala Ser Leu Tyr Leu Arg Pro Phe Met Ile Ser 135 140 145 acc gaa att ggc ttg ggt gtc agc cca gct gat gcc tac aag ttc ctg 595 Thr Glu Ile Gly Leu Gly Val Ser Pro Ala Asp Ala Tyr Lys Phe Leu 150 155 160 165 gtc atc gca tcc cca gtc ggc gct tac ttc acc ggt gga atc aag cct 643 Val Ile Ala Ser Pro Val Gly Ala Tyr Phe Thr Gly Gly Ile Lys Pro 170 175 180 gtt tcc gtc tgg ctg agc gaa gat tac gtc cgc gct gca ccc ggc gga 691 Val Ser Val Trp Leu Ser Glu Asp Tyr Val Arg Ala Ala Pro Gly Gly 185 190 195 act ggt gac gcc aaa ttt gct ggc aac tac gcg gct tct ttg ctt gcc 739 Thr Gly Asp Ala Lys Phe Ala Gly Asn Tyr Ala Ala Ser Leu Leu Ala 200 205 210 cag tcc cag gct gcg gaa aag ggc tgt gac cag gtc gta tgg ttg gat 787 Gln Ser Gln Ala Ala Glu Lys Gly Cys Asp Gln Val Val Trp Leu Asp 215 220 225 gcc atc gag cac aag tac atc gaa gaa atg ggt ggc atg aac ctt ggg 835 Ala Ile Glu His Lys Tyr Ile Glu Glu Met Gly Gly Met Asn Leu Gly 230 235 240 245 ttc atc tac cgc aac ggc gac caa gtc aag cta gtc acc cct gaa ctt 883 Phe Ile Tyr Arg Asn Gly Asp Gln Val Lys Leu Val Thr Pro Glu Leu 250 255 260 tcc ggc tca cta ctt cca ggc atc acc cgc aag tca ctt cta caa gta 931 Ser Gly Ser Leu Leu Pro Gly Ile Thr Arg Lys Ser Leu Leu Gln Val 265 270 275 gca cgc gac ttg gga tac gaa gta gaa gag cga aag atc acc acc acc 979 Ala Arg Asp Leu Gly Tyr Glu Val Glu Glu Arg Lys Ile Thr Thr Thr 280 285 290 gag tgg gaa gaa gac gca aag tct ggc gcc atg acc gag gca ttt gct 1027 Glu Trp Glu Glu Asp Ala Lys Ser Gly Ala Met Thr Glu Ala Phe Ala 295 300 305 tgc ggt act gca gct gtt atc acc cct gtt ggc acc gtg aaa tca gct 1075 Cys Gly Thr Ala Ala Val Ile Thr Pro Val Gly Thr Val Lys Ser Ala 310 315 320 325 cac ggc acc ttc gaa gtg aac aac aat gaa gtc gga gaa atc acg atg 1123 His Gly Thr Phe Glu Val Asn Asn Asn Glu Val Gly Glu Ile Thr Met 330 335 340 aag ctt cgt gaa acc ctc acc gga att cag caa gga aac gtt gaa gac 1171 Lys Leu Arg Glu Thr Leu Thr Gly Ile Gln Gln Gly Asn Val Glu Asp 345 350 355 caa aac gga tgg ctt tac cca ctg gtt ggc taaatcaacc ggttttaaga 1221 Gln Asn Gly Trp Leu Tyr Pro Leu Val Gly 360 365 ccc 1224 <210> 262 <211> 367 <212> PRT <213> Corynebacterium glutamicum <400> 262 Met Thr Ser Leu Glu Phe Thr Val Thr Arg Thr Glu Asn Pro Thr Ser 1 5 10 15 Pro Asp Arg Leu Lys Glu Ile Leu Ala Ala Pro Lys Phe Gly Lys Phe 20 25 30 Phe Thr Asp His Met Val Thr Ile Asp Trp Asn Glu Ser Glu Gly Trp 35 40 45 His Asn Ala Gln Leu Val Pro Tyr Ala Pro Ile Pro Met Asp Pro Ala 50 55 60 Thr Thr Val Phe His Tyr Gly Gln Ala Ile Phe Glu Gly Ile Lys Ala 65 70 75 80 Tyr Arg His Ser Asp Glu Thr Ile Lys Thr Phe Arg Pro Asp Glu Asn 85 90 95 Ala Glu Arg Met Gln Arg Ser Ala Ala Arg Met Ala Met Pro Gln Leu 100 105 110 Pro Thr Glu Asp Phe Ile Lys Ala Leu Glu Leu Leu Val Asp Ala Asp 115 120 125 Gln Asp Trp Val Pro Glu Tyr Gly Gly Glu Ala Ser Leu Tyr Leu Arg 130 135 140 Pro Phe Met Ile Ser Thr Glu Ile Gly Leu Gly Val Ser Pro Ala Asp 145 150 155 160 Ala Tyr Lys Phe Leu Val Ile Ala Ser Pro Val Gly Ala Tyr Phe Thr 165 170 175 Gly Gly Ile Lys Pro Val Ser Val Trp Leu Ser Glu Asp Tyr Val Arg 180 185 190 Ala Ala Pro Gly Gly Thr Gly Asp Ala Lys Phe Ala Gly Asn Tyr Ala 195 200 205 Ala Ser Leu Leu Ala Gln Ser Gln Ala Ala Glu Lys Gly Cys Asp Gln 210 215 220 Val Val Trp Leu Asp Ala Ile Glu His Lys Tyr Ile Glu Glu Met Gly 225 230 235 240 Gly Met Asn Leu Gly Phe Ile Tyr Arg Asn Gly Asp Gln Val Lys Leu 245 250 255 Val Thr Pro Glu Leu Ser Gly Ser Leu Leu Pro Gly Ile Thr Arg Lys 260 265 270 Ser Leu Leu Gln Val Ala Arg Asp Leu Gly Tyr Glu Val Glu Glu Arg 275 280 285 Lys Ile Thr Thr Thr Glu Trp Glu Glu Asp Ala Lys Ser Gly Ala Met 290 295 300 Thr Glu Ala Phe Ala Cys Gly Thr Ala Ala Val Ile Thr Pro Val Gly 305 310 315 320 Thr Val Lys Ser Ala His Gly Thr Phe Glu Val Asn Asn Asn Glu Val 325 330 335 Gly Glu Ile Thr Met Lys Leu Arg Glu Thr Leu Thr Gly Ile Gln Gln 340 345 350 Gly Asn Val Glu Asp Gln Asn Gly Trp Leu Tyr Pro Leu Val Gly 355 360 365 <210> 263 <211> 1076 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1053) <223> FRXA01690 <400> 263 ccc gat cgt ctg aag gaa att ctt gcc gca ccg aag ttc ggt aag ttc 48 Pro Asp Arg Leu Lys Glu Ile Leu Ala Ala Pro Lys Phe Gly Lys Phe 1 5 10 15 ttc acc gac cac atg gtg acc att gac tgg aac gag tcg gaa ggc tgg 96 Phe Thr Asp His Met Val Thr Ile Asp Trp Asn Glu Ser Glu Gly Trp 20 25 30 cac aac gcc caa tta gtg cca tac gcg ccg att cct atg gat cct gcc 144 His Asn Ala Gln Leu Val Pro Tyr Ala Pro Ile Pro Met Asp Pro Ala 35 40 45 acc acc gta ttc cac tac gga cag gca att ttt gag gga att aag gcc 192 Thr Thr Val Phe His Tyr Gly Gln Ala Ile Phe Glu Gly Ile Lys Ala 50 55 60 tac cgc cat tcg gac gaa acc atc aag act ttc cgt cct gat gaa aac 240 Tyr Arg His Ser Asp Glu Thr Ile Lys Thr Phe Arg Pro Asp Glu Asn 65 70 75 80 gcc gag cgt atg cag cgt tca gca gct cga atg gca atg cca cag ttg 288 Ala Glu Arg Met Gln Arg Ser Ala Ala Arg Met Ala Met Pro Gln Leu 85 90 95 cca acc gag gac ttt att aaa gca ctt gaa ctg ctg gta gac gcg gat 336 Pro Thr Glu Asp Phe Ile Lys Ala Leu Glu Leu Leu Val Asp Ala Asp 100 105 110 cag gat tgg gtt cct gag tac ggc gga gaa gct tcc ctc tac ctg cgc 384 Gln Asp Trp Val Pro Glu Tyr Gly Gly Glu Ala Ser Leu Tyr Leu Arg 115 120 125 cca ttc atg atc tcc acc gaa att ggc ttg ggt gtc agc cca gct gat 432 Pro Phe Met Ile Ser Thr Glu Ile Gly Leu Gly Val Ser Pro Ala Asp 130 135 140 gcc tac aag ttc ctg gtc atc gca tcc cca gtc ggc gct tac ttc acc 480 Ala Tyr Lys Phe Leu Val Ile Ala Ser Pro Val Gly Ala Tyr Phe Thr 145 150 155 160 ggt gga atc aag cct gtt tcc gtc tgg ctg agc gaa gat tac gtc cgc 528 Gly Gly Ile Lys Pro Val Ser Val Trp Leu Ser Glu Asp Tyr Val Arg 165 170 175 gct gca ccc ggc gga act ggt gac gcc aaa ttt gct ggc aac tac gcg 576 Ala Ala Pro Gly Gly Thr Gly Asp Ala Lys Phe Ala Gly Asn Tyr Ala 180 185 190 gct tct ttg ctt gcc cag tcc cag gct gcg gaa aag ggc tgt gac cag 624 Ala Ser Leu Leu Ala Gln Ser Gln Ala Ala Glu Lys Gly Cys Asp Gln 195 200 205 gtc gta tgg ttg gat gcc atc gag cac aag tac atc gaa gaa atg ggt 672 Val Val Trp Leu Asp Ala Ile Glu His Lys Tyr Ile Glu Glu Met Gly 210 215 220 ggc atg aac ctt ggg ttc atc tac cgc aac ggc gac caa gtc aag cta 720 Gly Met Asn Leu Gly Phe Ile Tyr Arg Asn Gly Asp Gln Val Lys Leu 225 230 235 240 gtc acc cct gaa ctt tcc ggc tca cta ctt cca ggc atc acc cgc aag 768 Val Thr Pro Glu Leu Ser Gly Ser Leu Leu Pro Gly Ile Thr Arg Lys 245 250 255 tca ctt cta caa gta gca cgc gac ttg gga tac gaa gta gaa gag cga 816 Ser Leu Leu Gln Val Ala Arg Asp Leu Gly Tyr Glu Val Glu Glu Arg 260 265 270 aag atc acc acc acc gag tgg gaa gaa gac gca aag tct ggc gcc atg 864 Lys Ile Thr Thr Thr Glu Trp Glu Glu Asp Ala Lys Ser Gly Ala Met 275 280 285 acc gag gca ttt gct tgc ggt act gca gct gtt atc acc cct gtt ggc 912 Thr Glu Ala Phe Ala Cys Gly Thr Ala Ala Val Ile Thr Pro Val Gly 290 295 300 acc gtg aaa tca gct cac ggc acc ttc gaa gtg aac aac aat gaa gtc 960 Thr Val Lys Ser Ala His Gly Thr Phe Glu Val Asn Asn Asn Glu Val 305 310 315 320 gga gaa atc acg atg aag ctt cgt gaa acc ctc acc gga att cag caa 1008 Gly Glu Ile Thr Met Lys Leu Arg Glu Thr Leu Thr Gly Ile Gln Gln 325 330 335 gga aac gtt gaa gac caa aac gga tgg ctt tac cca ctg gtt ggc 1053 Gly Asn Val Glu Asp Gln Asn Gly Trp Leu Tyr Pro Leu Val Gly 340 345 350 taaatcaacc ggttttaaga ccc 1076 <210> 264 <211> 351 <212> PRT <213> Corynebacterium glutamicum <400> 264 Pro Asp Arg Leu Lys Glu Ile Leu Ala Ala Pro Lys Phe Gly Lys Phe 1 5 10 15 Phe Thr Asp His Met Val Thr Ile Asp Trp Asn Glu Ser Glu Gly Trp 20 25 30 His Asn Ala Gln Leu Val Pro Tyr Ala Pro Ile Pro Met Asp Pro Ala 35 40 45 Thr Thr Val Phe His Tyr Gly Gln Ala Ile Phe Glu Gly Ile Lys Ala 50 55 60 Tyr Arg His Ser Asp Glu Thr Ile Lys Thr Phe Arg Pro Asp Glu Asn 65 70 75 80 Ala Glu Arg Met Gln Arg Ser Ala Ala Arg Met Ala Met Pro Gln Leu 85 90 95 Pro Thr Glu Asp Phe Ile Lys Ala Leu Glu Leu Leu Val Asp Ala Asp 100 105 110 Gln Asp Trp Val Pro Glu Tyr Gly Gly Glu Ala Ser Leu Tyr Leu Arg 115 120 125 Pro Phe Met Ile Ser Thr Glu Ile Gly Leu Gly Val Ser Pro Ala Asp 130 135 140 Ala Tyr Lys Phe Leu Val Ile Ala Ser Pro Val Gly Ala Tyr Phe Thr 145 150 155 160 Gly Gly Ile Lys Pro Val Ser Val Trp Leu Ser Glu Asp Tyr Val Arg 165 170 175 Ala Ala Pro Gly Gly Thr Gly Asp Ala Lys Phe Ala Gly Asn Tyr Ala 180 185 190 Ala Ser Leu Leu Ala Gln Ser Gln Ala Ala Glu Lys Gly Cys Asp Gln 195 200 205 Val Val Trp Leu Asp Ala Ile Glu His Lys Tyr Ile Glu Glu Met Gly 210 215 220 Gly Met Asn Leu Gly Phe Ile Tyr Arg Asn Gly Asp Gln Val Lys Leu 225 230 235 240 Val Thr Pro Glu Leu Ser Gly Ser Leu Leu Pro Gly Ile Thr Arg Lys 245 250 255 Ser Leu Leu Gln Val Ala Arg Asp Leu Gly Tyr Glu Val Glu Glu Arg 260 265 270 Lys Ile Thr Thr Thr Glu Trp Glu Glu Asp Ala Lys Ser Gly Ala Met 275 280 285 Thr Glu Ala Phe Ala Cys Gly Thr Ala Ala Val Ile Thr Pro Val Gly 290 295 300 Thr Val Lys Ser Ala His Gly Thr Phe Glu Val Asn Asn Asn Glu Val 305 310 315 320 Gly Glu Ile Thr Met Lys Leu Arg Glu Thr Leu Thr Gly Ile Gln Gln 325 330 335 Gly Asn Val Glu Asp Gln Asn Gly Trp Leu Tyr Pro Leu Val Gly 340 345 350 <210> 265 <211> 1782 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1759) <223> RXN01026 <400> 265 gaggtgacat ttatgcctct taatagctat actgtcccat gaaacgatat tttaatctca 60 tatagtgaga tttacagatt tttaaaggac ggtgagttcc atg acc agc ccc gtg 115 Met Thr Ser Pro Val 1 5 gag aac agc acc tca act gag aag ctg acc ctg gca gag aag gtg tgg 163 Glu Asn Ser Thr Ser Thr Glu Lys Leu Thr Leu Ala Glu Lys Val Trp 10 15 20 cgc gac cat gtc gtg tcc aag gga gaa aac ggc gag ccc gac ctc ctc 211 Arg Asp His Val Val Ser Lys Gly Glu Asn Gly Glu Pro Asp Leu Leu 25 30 35 tac atc gac ctg cag ctg ctg cat gaa gtg acc tca cca cag gca ttt 259 Tyr Ile Asp Leu Gln Leu Leu His Glu Val Thr Ser Pro Gln Ala Phe 40 45 50 gac ggc ctg cgc atg acc ggc cgt aaa ctg cgc cac cca gaa ctg cac 307 Asp Gly Leu Arg Met Thr Gly Arg Lys Leu Arg His Pro Glu Leu His 55 60 65 ctg gcc acc gaa gac cac aac gtg cca acc gaa ggc atc aag act ggc 355 Leu Ala Thr Glu Asp His Asn Val Pro Thr Glu Gly Ile Lys Thr Gly 70 75 80 85 tca ctg ctg gaa atc aac gac aag att tcc cgc ctg cag gta tct act 403 Ser Leu Leu Glu Ile Asn Asp Lys Ile Ser Arg Leu Gln Val Ser Thr 90 95 100 ctg cgc gac aac tgt gaa gaa ttc ggc gtg cgc ctg cac cca atg ggt 451 Leu Arg Asp Asn Cys Glu Glu Phe Gly Val Arg Leu His Pro Met Gly 105 110 115 gat gtc cga cag ggc atc gtg cac acc gtc ggc cca cag ctc ggc gca 499 Asp Val Arg Gln Gly Ile Val His Thr Val Gly Pro Gln Leu Gly Ala 120 125 130 acc cag cca ggc atg acc att gtg tgc ggt gac tcc cac acc tcc acc 547 Thr Gln Pro Gly Met Thr Ile Val Cys Gly Asp Ser His Thr Ser Thr 135 140 145 cac ggt gct ttt ggc tcc atg gca ttc ggc atc ggt acc tca gag gtt 595 His Gly Ala Phe Gly Ser Met Ala Phe Gly Ile Gly Thr Ser Glu Val 150 155 160 165 gag cac gtc atg gct act caa acc ctg cca ctg aag cct ttc aag acc 643 Glu His Val Met Ala Thr Gln Thr Leu Pro Leu Lys Pro Phe Lys Thr 170 175 180 atg gcc att gaa gtt act ggt gaa ctg cag cca ggt gtt tcc tcc aag 691 Met Ala Ile Glu Val Thr Gly Glu Leu Gln Pro Gly Val Ser Ser Lys 185 190 195 gac ctg att ctg gcg att atc gcc aag atc ggc acc ggc ggc gga cag 739 Asp Leu Ile Leu Ala Ile Ile Ala Lys Ile Gly Thr Gly Gly Gly Gln 200 205 210 ggc tac gtt ctg gaa tac cgc ggc gaa gca atc cgt aag atg tcc atg 787 Gly Tyr Val Leu Glu Tyr Arg Gly Glu Ala Ile Arg Lys Met Ser Met 215 220 225 gat gca cgc atg acc atg tgc aac atg tcc atc gaa gct ggc gca cgt 835 Asp Ala Arg Met Thr Met Cys Asn Met Ser Ile Glu Ala Gly Ala Arg 230 235 240 245 gcc ggc atg atc gcc cca gac caa acc acc ttc gac tac gtt gaa ggc 883 Ala Gly Met Ile Ala Pro Asp Gln Thr Thr Phe Asp Tyr Val Glu Gly 250 255 260 cgc gaa atg gca cca aag ggc gcc gac tgg gac gaa gca gtt gct tac 931 Arg Glu Met Ala Pro Lys Gly Ala Asp Trp Asp Glu Ala Val Ala Tyr 265 270 275 tgg aag acc ctg cca acc gac gaa ggc gca acc ttt gac aag gtc gta 979 Trp Lys Thr Leu Pro Thr Asp Glu Gly Ala Thr Phe Asp Lys Val Val 280 285 290 gaa atc gat ggc tcg gca ctg acc cca ttc atc acc tgg ggc acc aac 1027 Glu Ile Asp Gly Ser Ala Leu Thr Pro Phe Ile Thr Trp Gly Thr Asn 295 300 305 cca ggc cag ggc ctg cca ctg ggc gaa tcc gta cca agc cca gaa gac 1075 Pro Gly Gln Gly Leu Pro Leu Gly Glu Ser Val Pro Ser Pro Glu Asp 310 315 320 325 ttc acc aac gac aac gac aag gca gca gcc gaa aag gca ctg cag tac 1123 Phe Thr Asn Asp Asn Asp Lys Ala Ala Ala Glu Lys Ala Leu Gln Tyr 330 335 340 atg gac ctg gta cca gga acc cca ctg cgc gac atc aag atc gac acc 1171 Met Asp Leu Val Pro Gly Thr Pro Leu Arg Asp Ile Lys Ile Asp Thr 345 350 355 gtc ttc ctg gga tcc tgc acc aac gcc cgc atc gaa gac ctg cag atc 1219 Val Phe Leu Gly Ser Cys Thr Asn Ala Arg Ile Glu Asp Leu Gln Ile 360 365 370 gcc gct gac atc ctc aag ggc cac aaa atc gcc gac ggc atg cgc atg 1267 Ala Ala Asp Ile Leu Lys Gly His Lys Ile Ala Asp Gly Met Arg Met 375 380 385 atg gtc gtg cct tcc tcc acc tgg atc aag caa gag gca gaa gcg ctc 1315 Met Val Val Pro Ser Ser Thr Trp Ile Lys Gln Glu Ala Glu Ala Leu 390 395 400 405 gga ctg gac aaa atc ttc acc gac gct ggc gct gaa tgg cgt acc gca 1363 Gly Leu Asp Lys Ile Phe Thr Asp Ala Gly Ala Glu Trp Arg Thr Ala 410 415 420 ggc tgc tcc atg tgc ctg ggc atg aac cca gac caa ctg aag cca ggc 1411 Gly Cys Ser Met Cys Leu Gly Met Asn Pro Asp Gln Leu Lys Pro Gly 425 430 435 gag cgc tcc gca ttc acc tcc aac cga aac ttc gaa gga cgc caa gga 1459 Glu Arg Ser Ala Phe Thr Ser Asn Arg Asn Phe Glu Gly Arg Gln Gly 440 445 450 cca gga ggc cgc acc cac ctg gta tcc cca gca gtc gca gcc gcc acc 1507 Pro Gly Gly Arg Thr His Leu Val Ser Pro Ala Val Ala Ala Ala Thr 455 460 465 gaa tcc gcg gac cct gtc ctc acc tgc aga tat cta agg aag gct aga 1555 Glu Ser Ala Asp Pro Val Leu Thr Cys Arg Tyr Leu Arg Lys Ala Arg 470 475 480 485 aaa caa tgg aaa aat tta cca cct aca ccg gcg ttg gcg ttc cac tgc 1603 Lys Gln Trp Lys Asn Leu Pro Pro Thr Pro Ala Leu Ala Phe His Cys 490 495 500 agc gat cca acg tgg aca ccg acc aga tca tcc cag ccg tct acc tca 1651 Ser Asp Pro Thr Trp Thr Pro Thr Arg Ser Ser Gln Pro Ser Thr Ser 505 510 515 agc gcg tca ccc gga ccg gct tcg aag acg gac tgt ttt cca act ggc 1699 Ser Ala Ser Pro Gly Pro Ala Ser Lys Thr Asp Cys Phe Pro Thr Gly 520 525 530 gcc aaa acg acc cca act ttg tcc tca aca ccg aca cct aca aga acg 1747 Ala Lys Thr Thr Pro Thr Leu Ser Ser Thr Pro Thr Pro Thr Arg Thr 535 540 545 gct ccg ttc tcg tagcaggccc tgactttggc acc 1782 Ala Pro Phe Ser 550 <210> 266 <211> 553 <212> PRT <213> Corynebacterium glutamicum <400> 266 Met Thr Ser Pro Val Glu Asn Ser Thr Ser Thr Glu Lys Leu Thr Leu 1 5 10 15 Ala Glu Lys Val Trp Arg Asp His Val Val Ser Lys Gly Glu Asn Gly 20 25 30 Glu Pro Asp Leu Leu Tyr Ile Asp Leu Gln Leu Leu His Glu Val Thr 35 40 45 Ser Pro Gln Ala Phe Asp Gly Leu Arg Met Thr Gly Arg Lys Leu Arg 50 55 60 His Pro Glu Leu His Leu Ala Thr Glu Asp His Asn Val Pro Thr Glu 65 70 75 80 Gly Ile Lys Thr Gly Ser Leu Leu Glu Ile Asn Asp Lys Ile Ser Arg 85 90 95 Leu Gln Val Ser Thr Leu Arg Asp Asn Cys Glu Glu Phe Gly Val Arg 100 105 110 Leu His Pro Met Gly Asp Val Arg Gln Gly Ile Val His Thr Val Gly 115 120 125 Pro Gln Leu Gly Ala Thr Gln Pro Gly Met Thr Ile Val Cys Gly Asp 130 135 140 Ser His Thr Ser Thr His Gly Ala Phe Gly Ser Met Ala Phe Gly Ile 145 150 155 160 Gly Thr Ser Glu Val Glu His Val Met Ala Thr Gln Thr Leu Pro Leu 165 170 175 Lys Pro Phe Lys Thr Met Ala Ile Glu Val Thr Gly Glu Leu Gln Pro 180 185 190 Gly Val Ser Ser Lys Asp Leu Ile Leu Ala Ile Ile Ala Lys Ile Gly 195 200 205 Thr Gly Gly Gly Gln Gly Tyr Val Leu Glu Tyr Arg Gly Glu Ala Ile 210 215 220 Arg Lys Met Ser Met Asp Ala Arg Met Thr Met Cys Asn Met Ser Ile 225 230 235 240 Glu Ala Gly Ala Arg Ala Gly Met Ile Ala Pro Asp Gln Thr Thr Phe 245 250 255 Asp Tyr Val Glu Gly Arg Glu Met Ala Pro Lys Gly Ala Asp Trp Asp 260 265 270 Glu Ala Val Ala Tyr Trp Lys Thr Leu Pro Thr Asp Glu Gly Ala Thr 275 280 285 Phe Asp Lys Val Val Glu Ile Asp Gly Ser Ala Leu Thr Pro Phe Ile 290 295 300 Thr Trp Gly Thr Asn Pro Gly Gln Gly Leu Pro Leu Gly Glu Ser Val 305 310 315 320 Pro Ser Pro Glu Asp Phe Thr Asn Asp Asn Asp Lys Ala Ala Ala Glu 325 330 335 Lys Ala Leu Gln Tyr Met Asp Leu Val Pro Gly Thr Pro Leu Arg Asp 340 345 350 Ile Lys Ile Asp Thr Val Phe Leu Gly Ser Cys Thr Asn Ala Arg Ile 355 360 365 Glu Asp Leu Gln Ile Ala Ala Asp Ile Leu Lys Gly His Lys Ile Ala 370 375 380 Asp Gly Met Arg Met Met Val Val Pro Ser Ser Thr Trp Ile Lys Gln 385 390 395 400 Glu Ala Glu Ala Leu Gly Leu Asp Lys Ile Phe Thr Asp Ala Gly Ala 405 410 415 Glu Trp Arg Thr Ala Gly Cys Ser Met Cys Leu Gly Met Asn Pro Asp 420 425 430 Gln Leu Lys Pro Gly Glu Arg Ser Ala Phe Thr Ser Asn Arg Asn Phe 435 440 445 Glu Gly Arg Gln Gly Pro Gly Gly Arg Thr His Leu Val Ser Pro Ala 450 455 460 Val Ala Ala Ala Thr Glu Ser Ala Asp Pro Val Leu Thr Cys Arg Tyr 465 470 475 480 Leu Arg Lys Ala Arg Lys Gln Trp Lys Asn Leu Pro Pro Thr Pro Ala 485 490 495 Leu Ala Phe His Cys Ser Asp Pro Thr Trp Thr Pro Thr Arg Ser Ser 500 505 510 Gln Pro Ser Thr Ser Ser Ala Ser Pro Gly Pro Ala Ser Lys Thr Asp 515 520 525 Cys Phe Pro Thr Gly Ala Lys Thr Thr Pro Thr Leu Ser Ser Thr Pro 530 535 540 Thr Pro Thr Arg Thr Ala Pro Phe Ser 545 550 <210> 267 <211> 1625 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1602) <223> FRXA01026 <400> 267 gtg tgg cgc gac cat gtc gtg tcc aag gga gaa aac ggc gag ccc gac 48 Val Trp Arg Asp His Val Val Ser Lys Gly Glu Asn Gly Glu Pro Asp 1 5 10 15 ctc ctc tac atc gac ctg cag ctg ctg cat gaa gtg acc tca cca cag 96 Leu Leu Tyr Ile Asp Leu Gln Leu Leu His Glu Val Thr Ser Pro Gln 20 25 30 gca ttt gac ggc ctg cgc atg acc ggc cgt aaa ctg cgc cac cca gaa 144 Ala Phe Asp Gly Leu Arg Met Thr Gly Arg Lys Leu Arg His Pro Glu 35 40 45 ctg cac ctg gcc acc gaa gac cac aac gtg cca acc gaa ggc atc aag 192 Leu His Leu Ala Thr Glu Asp His Asn Val Pro Thr Glu Gly Ile Lys 50 55 60 act ggc tca ctg ctg gaa atc aac gac aag att tcc cgc ctg cag gta 240 Thr Gly Ser Leu Leu Glu Ile Asn Asp Lys Ile Ser Arg Leu Gln Val 65 70 75 80 tct act ctg cgc gac aac tgt gaa gaa ttc ggc gtg cgc ctg cac cca 288 Ser Thr Leu Arg Asp Asn Cys Glu Glu Phe Gly Val Arg Leu His Pro 85 90 95 atg ggt gat gtc cga cag ggc atc gtg cac acc gtc ggc cca cag ctc 336 Met Gly Asp Val Arg Gln Gly Ile Val His Thr Val Gly Pro Gln Leu 100 105 110 ggc gca acc cag cca ggc atg acc att gtg tgc ggt gac tcc cac acc 384 Gly Ala Thr Gln Pro Gly Met Thr Ile Val Cys Gly Asp Ser His Thr 115 120 125 tcc acc cac ggt gct ttt ggc tcc atg gca ttc ggc atc ggt acc tca 432 Ser Thr His Gly Ala Phe Gly Ser Met Ala Phe Gly Ile Gly Thr Ser 130 135 140 gag gtt gag cac gtc atg gct act caa acc ctg cca ctg aag cct ttc 480 Glu Val Glu His Val Met Ala Thr Gln Thr Leu Pro Leu Lys Pro Phe 145 150 155 160 aag acc atg gcc att gaa gtt act ggt gaa ctg cag cca ggt gtt tcc 528 Lys Thr Met Ala Ile Glu Val Thr Gly Glu Leu Gln Pro Gly Val Ser 165 170 175 tcc aag gac ctg att ctg gcg att atc gcc aag atc ggc acc ggc ggc 576 Ser Lys Asp Leu Ile Leu Ala Ile Ile Ala Lys Ile Gly Thr Gly Gly 180 185 190 gga cag ggc tac gtt ctg gaa tac cgc ggc gaa gca atc cgt aag atg 624 Gly Gln Gly Tyr Val Leu Glu Tyr Arg Gly Glu Ala Ile Arg Lys Met 195 200 205 tcc atg gat gca cgc atg acc atg tgc aac atg tcc atc gaa gct ggc 672 Ser Met Asp Ala Arg Met Thr Met Cys Asn Met Ser Ile Glu Ala Gly 210 215 220 gca cgt gcc ggc atg atc gcc cca gac caa acc acc ttc gac tac gtt 720 Ala Arg Ala Gly Met Ile Ala Pro Asp Gln Thr Thr Phe Asp Tyr Val 225 230 235 240 gaa ggc cgc gaa atg gca cca aag ggc gcc gac tgg gac gaa gca gtt 768 Glu Gly Arg Glu Met Ala Pro Lys Gly Ala Asp Trp Asp Glu Ala Val 245 250 255 gct tac tgg aag acc ctg cca acc gac gaa ggc gca acc ttt gac aag 816 Ala Tyr Trp Lys Thr Leu Pro Thr Asp Glu Gly Ala Thr Phe Asp Lys 260 265 270 gtc gta gaa atc gat ggc tcg gca ctg acc cca ttc atc acc tgg ggc 864 Val Val Glu Ile Asp Gly Ser Ala Leu Thr Pro Phe Ile Thr Trp Gly 275 280 285 acc aac cca ggc cag ggc ctg cca ctg ggc gaa tcc gta cca agc cca 912 Thr Asn Pro Gly Gln Gly Leu Pro Leu Gly Glu Ser Val Pro Ser Pro 290 295 300 gaa gac ttc acc aac gac aac gac aag gca gca gcc gaa aag gca ctg 960 Glu Asp Phe Thr Asn Asp Asn Asp Lys Ala Ala Ala Glu Lys Ala Leu 305 310 315 320 cag tac atg gac ctg gta cca gga acc cca ctg cgc gac atc aag atc 1008 Gln Tyr Met Asp Leu Val Pro Gly Thr Pro Leu Arg Asp Ile Lys Ile 325 330 335 gac acc gtc ttc ctg gga tcc tgc acc aac gcc cgc atc gaa gac ctg 1056 Asp Thr Val Phe Leu Gly Ser Cys Thr Asn Ala Arg Ile Glu Asp Leu 340 345 350 cag atc gcc gct gac atc ctc aag ggc cac aaa atc gcc gac ggc atg 1104 Gln Ile Ala Ala Asp Ile Leu Lys Gly His Lys Ile Ala Asp Gly Met 355 360 365 cgc atg atg gtc gtg cct tcc tcc acc tgg atc aag caa gag gca gaa 1152 Arg Met Met Val Val Pro Ser Ser Thr Trp Ile Lys Gln Glu Ala Glu 370 375 380 gcg ctc gga ctg gac aaa atc ttc acc gac gct ggc gct gaa tgg cgt 1200 Ala Leu Gly Leu Asp Lys Ile Phe Thr Asp Ala Gly Ala Glu Trp Arg 385 390 395 400 acc gca ggc tgc tcc atg tgc ctg ggc atg aac cca gac caa ctg aag 1248 Thr Ala Gly Cys Ser Met Cys Leu Gly Met Asn Pro Asp Gln Leu Lys 405 410 415 cca ggc gag cgc tcc gca ttc acc tcc aac cga aac ttc gaa gga cgc 1296 Pro Gly Glu Arg Ser Ala Phe Thr Ser Asn Arg Asn Phe Glu Gly Arg 420 425 430 caa gga cca gga ggc cgc acc cac ctg gta tcc cca gca gtc gca gcc 1344 Gln Gly Pro Gly Gly Arg Thr His Leu Val Ser Pro Ala Val Ala Ala 435 440 445 gcc acc gaa tcc gcg gac cct gtc ctc acc tgc aga tat cta agg aag 1392 Ala Thr Glu Ser Ala Asp Pro Val Leu Thr Cys Arg Tyr Leu Arg Lys 450 455 460 gct aga aaa caa tgg aaa aat tta cca cct aca ccg gcg ttg gcg ttc 1440 Ala Arg Lys Gln Trp Lys Asn Leu Pro Pro Thr Pro Ala Leu Ala Phe 465 470 475 480 cac tgc agc gat cca acg tgg aca ccg acc aga tca tcc cag ccg tct 1488 His Cys Ser Asp Pro Thr Trp Thr Pro Thr Arg Ser Ser Gln Pro Ser 485 490 495 acc tca agc gcg tca ccc gga ccg gct tcg aag acg gac tgt ttt cca 1536 Thr Ser Ser Ala Ser Pro Gly Pro Ala Ser Lys Thr Asp Cys Phe Pro 500 505 510 act ggc gcc aaa acg acc cca act ttg tcc tca aca ccg aca cct aca 1584 Thr Gly Ala Lys Thr Thr Pro Thr Leu Ser Ser Thr Pro Thr Pro Thr 515 520 525 aga acg gct ccg ttc tcg tagcaggccc tgactttggc acc 1625 Arg Thr Ala Pro Phe Ser 530 <210> 268 <211> 534 <212> PRT <213> Corynebacterium glutamicum <400> 268 Val Trp Arg Asp His Val Val Ser Lys Gly Glu Asn Gly Glu Pro Asp 1 5 10 15 Leu Leu Tyr Ile Asp Leu Gln Leu Leu His Glu Val Thr Ser Pro Gln 20 25 30 Ala Phe Asp Gly Leu Arg Met Thr Gly Arg Lys Leu Arg His Pro Glu 35 40 45 Leu His Leu Ala Thr Glu Asp His Asn Val Pro Thr Glu Gly Ile Lys 50 55 60 Thr Gly Ser Leu Leu Glu Ile Asn Asp Lys Ile Ser Arg Leu Gln Val 65 70 75 80 Ser Thr Leu Arg Asp Asn Cys Glu Glu Phe Gly Val Arg Leu His Pro 85 90 95 Met Gly Asp Val Arg Gln Gly Ile Val His Thr Val Gly Pro Gln Leu 100 105 110 Gly Ala Thr Gln Pro Gly Met Thr Ile Val Cys Gly Asp Ser His Thr 115 120 125 Ser Thr His Gly Ala Phe Gly Ser Met Ala Phe Gly Ile Gly Thr Ser 130 135 140 Glu Val Glu His Val Met Ala Thr Gln Thr Leu Pro Leu Lys Pro Phe 145 150 155 160 Lys Thr Met Ala Ile Glu Val Thr Gly Glu Leu Gln Pro Gly Val Ser 165 170 175 Ser Lys Asp Leu Ile Leu Ala Ile Ile Ala Lys Ile Gly Thr Gly Gly 180 185 190 Gly Gln Gly Tyr Val Leu Glu Tyr Arg Gly Glu Ala Ile Arg Lys Met 195 200 205 Ser Met Asp Ala Arg Met Thr Met Cys Asn Met Ser Ile Glu Ala Gly 210 215 220 Ala Arg Ala Gly Met Ile Ala Pro Asp Gln Thr Thr Phe Asp Tyr Val 225 230 235 240 Glu Gly Arg Glu Met Ala Pro Lys Gly Ala Asp Trp Asp Glu Ala Val 245 250 255 Ala Tyr Trp Lys Thr Leu Pro Thr Asp Glu Gly Ala Thr Phe Asp Lys 260 265 270 Val Val Glu Ile Asp Gly Ser Ala Leu Thr Pro Phe Ile Thr Trp Gly 275 280 285 Thr Asn Pro Gly Gln Gly Leu Pro Leu Gly Glu Ser Val Pro Ser Pro 290 295 300 Glu Asp Phe Thr Asn Asp Asn Asp Lys Ala Ala Ala Glu Lys Ala Leu 305 310 315 320 Gln Tyr Met Asp Leu Val Pro Gly Thr Pro Leu Arg Asp Ile Lys Ile 325 330 335 Asp Thr Val Phe Leu Gly Ser Cys Thr Asn Ala Arg Ile Glu Asp Leu 340 345 350 Gln Ile Ala Ala Asp Ile Leu Lys Gly His Lys Ile Ala Asp Gly Met 355 360 365 Arg Met Met Val Val Pro Ser Ser Thr Trp Ile Lys Gln Glu Ala Glu 370 375 380 Ala Leu Gly Leu Asp Lys Ile Phe Thr Asp Ala Gly Ala Glu Trp Arg 385 390 395 400 Thr Ala Gly Cys Ser Met Cys Leu Gly Met Asn Pro Asp Gln Leu Lys 405 410 415 Pro Gly Glu Arg Ser Ala Phe Thr Ser Asn Arg Asn Phe Glu Gly Arg 420 425 430 Gln Gly Pro Gly Gly Arg Thr His Leu Val Ser Pro Ala Val Ala Ala 435 440 445 Ala Thr Glu Ser Ala Asp Pro Val Leu Thr Cys Arg Tyr Leu Arg Lys 450 455 460 Ala Arg Lys Gln Trp Lys Asn Leu Pro Pro Thr Pro Ala Leu Ala Phe 465 470 475 480 His Cys Ser Asp Pro Thr Trp Thr Pro Thr Arg Ser Ser Gln Pro Ser 485 490 495 Thr Ser Ser Ala Ser Pro Gly Pro Ala Ser Lys Thr Asp Cys Phe Pro 500 505 510 Thr Gly Ala Lys Thr Thr Pro Thr Leu Ser Ser Thr Pro Thr Pro Thr 515 520 525 Arg Thr Ala Pro Phe Ser 530 <210> 269 <211> 1143 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1120) <223> RXN01127 <400> 269 gccctgcatg atggggtagt gggggttgtt gggcaggtac gagctgtgat caatcagcta 60 cactagtgaa gtccatatag tgagaaggga atcccacaac atg aaa ctt gct gtt 115 Met Lys Leu Ala Val 1 5 att ggt gga gat ggt atc ggc cca gag gtt act gca gaa gcc ctc aag 163 Ile Gly Gly Asp Gly Ile Gly Pro Glu Val Thr Ala Glu Ala Leu Lys 10 15 20 gtt cta aac gct gtc cgc gac gac atc gag acc acc gat tat gac ctt 211 Val Leu Asn Ala Val Arg Asp Asp Ile Glu Thr Thr Asp Tyr Asp Leu 25 30 35 ggc gca cgc cgt tac ctc aaa aat ggc gag ctg ctc acc gac gag gat 259 Gly Ala Arg Arg Tyr Leu Lys Asn Gly Glu Leu Leu Thr Asp Glu Asp 40 45 50 ctg gca tcc ctg cgc gag cat gac gcg atc ctt ctt ggc gct atc ggt 307 Leu Ala Ser Leu Arg Glu His Asp Ala Ile Leu Leu Gly Ala Ile Gly 55 60 65 gca cca ggt tcc gtc cct cca gga att ctc gag cgt ggt ttg ctg ctg 355 Ala Pro Gly Ser Val Pro Pro Gly Ile Leu Glu Arg Gly Leu Leu Leu 70 75 80 85 aag atg cga ttc gca ctg gat cac cac gtg aac ctg cgc cca tcc aag 403 Lys Met Arg Phe Ala Leu Asp His His Val Asn Leu Arg Pro Ser Lys 90 95 100 ctg tac gac ggc gtg gag tcc cca ctg cgt aac cca ggc aag att gat 451 Leu Tyr Asp Gly Val Glu Ser Pro Leu Arg Asn Pro Gly Lys Ile Asp 105 110 115 ttc gtt gtg gtc cgc gaa ggt acc gaa ggc gcc tac act ggc aac ggt 499 Phe Val Val Val Arg Glu Gly Thr Glu Gly Ala Tyr Thr Gly Asn Gly 120 125 130 gga gca atc cgc gtg gga acc cct cac gag att gcc aat gaa acc tcc 547 Gly Ala Ile Arg Val Gly Thr Pro His Glu Ile Ala Asn Glu Thr Ser 135 140 145 gtg aac act cgc tac ggc gct gag cgc gtt att cgc tac gca ttc gag 595 Val Asn Thr Arg Tyr Gly Ala Glu Arg Val Ile Arg Tyr Ala Phe Glu 150 155 160 165 ctg gca cag agc cgc cgc aag aag ctc acc ctc gtg cac aag acc aac 643 Leu Ala Gln Ser Arg Arg Lys Lys Leu Thr Leu Val His Lys Thr Asn 170 175 180 gtc ctg gtt cac ggt ggt ggc ctg tgg cag cgc acc gta gat gag gtt 691 Val Leu Val His Gly Gly Gly Leu Trp Gln Arg Thr Val Asp Glu Val 185 190 195 gca aag gaa tac cca gag gta gcc gtc gat tac aac cac atc gat gca 739 Ala Lys Glu Tyr Pro Glu Val Ala Val Asp Tyr Asn His Ile Asp Ala 200 205 210 gca acc atc tat ctg gtc act gat cct tcc cgc ttc gat gtg att gtt 787 Ala Thr Ile Tyr Leu Val Thr Asp Pro Ser Arg Phe Asp Val Ile Val 215 220 225 acc gat aac ctc ttc ggc gac atc ctc acc gat gag gca ggc gca gtc 835 Thr Asp Asn Leu Phe Gly Asp Ile Leu Thr Asp Glu Ala Gly Ala Val 230 235 240 245 tct ggc gga att ggc ctc gca gca tcc ggc aac atc gat gcc acg ggc 883 Ser Gly Gly Ile Gly Leu Ala Ala Ser Gly Asn Ile Asp Ala Thr Gly 250 255 260 acc aac cct tcc atg ttc gag cca gtc cac ggc tct gca cca gat atc 931 Thr Asn Pro Ser Met Phe Glu Pro Val His Gly Ser Ala Pro Asp Ile 265 270 275 gca ggc cag gga atc gca gac cca acg gca gca atc cta tcc gct gcg 979 Ala Gly Gln Gly Ile Ala Asp Pro Thr Ala Ala Ile Leu Ser Ala Ala 280 285 290 atg ctg ctg cgt cac tta ggt gat gaa gac aac gca gta cgt att gaa 1027 Met Leu Leu Arg His Leu Gly Asp Glu Asp Asn Ala Val Arg Ile Glu 295 300 305 aca gcc atc gca gct gat gtg gct ggc cga gat aac tct cag ccg att 1075 Thr Ala Ile Ala Ala Asp Val Ala Gly Arg Asp Asn Ser Gln Pro Ile 310 315 320 325 tct acc act gag gtg gga gac cgc atc gtc aag gcg ctg caa agc 1120 Ser Thr Thr Glu Val Gly Asp Arg Ile Val Lys Ala Leu Gln Ser 330 335 340 taaatttcaa cgccgacccc ctt 1143 <210> 270 <211> 340 <212> PRT <213> Corynebacterium glutamicum <400> 270 Met Lys Leu Ala Val Ile Gly Gly Asp Gly Ile Gly Pro Glu Val Thr 1 5 10 15 Ala Glu Ala Leu Lys Val Leu Asn Ala Val Arg Asp Asp Ile Glu Thr 20 25 30 Thr Asp Tyr Asp Leu Gly Ala Arg Arg Tyr Leu Lys Asn Gly Glu Leu 35 40 45 Leu Thr Asp Glu Asp Leu Ala Ser Leu Arg Glu His Asp Ala Ile Leu 50 55 60 Leu Gly Ala Ile Gly Ala Pro Gly Ser Val Pro Pro Gly Ile Leu Glu 65 70 75 80 Arg Gly Leu Leu Leu Lys Met Arg Phe Ala Leu Asp His His Val Asn 85 90 95 Leu Arg Pro Ser Lys Leu Tyr Asp Gly Val Glu Ser Pro Leu Arg Asn 100 105 110 Pro Gly Lys Ile Asp Phe Val Val Val Arg Glu Gly Thr Glu Gly Ala 115 120 125 Tyr Thr Gly Asn Gly Gly Ala Ile Arg Val Gly Thr Pro His Glu Ile 130 135 140 Ala Asn Glu Thr Ser Val Asn Thr Arg Tyr Gly Ala Glu Arg Val Ile 145 150 155 160 Arg Tyr Ala Phe Glu Leu Ala Gln Ser Arg Arg Lys Lys Leu Thr Leu 165 170 175 Val His Lys Thr Asn Val Leu Val His Gly Gly Gly Leu Trp Gln Arg 180 185 190 Thr Val Asp Glu Val Ala Lys Glu Tyr Pro Glu Val Ala Val Asp Tyr 195 200 205 Asn His Ile Asp Ala Ala Thr Ile Tyr Leu Val Thr Asp Pro Ser Arg 210 215 220 Phe Asp Val Ile Val Thr Asp Asn Leu Phe Gly Asp Ile Leu Thr Asp 225 230 235 240 Glu Ala Gly Ala Val Ser Gly Gly Ile Gly Leu Ala Ala Ser Gly Asn 245 250 255 Ile Asp Ala Thr Gly Thr Asn Pro Ser Met Phe Glu Pro Val His Gly 260 265 270 Ser Ala Pro Asp Ile Ala Gly Gln Gly Ile Ala Asp Pro Thr Ala Ala 275 280 285 Ile Leu Ser Ala Ala Met Leu Leu Arg His Leu Gly Asp Glu Asp Asn 290 295 300 Ala Val Arg Ile Glu Thr Ala Ile Ala Ala Asp Val Ala Gly Arg Asp 305 310 315 320 Asn Ser Gln Pro Ile Ser Thr Thr Glu Val Gly Asp Arg Ile Val Lys 325 330 335 Ala Leu Gln Ser 340 <210> 271 <211> 403 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(403) <223> FRXA01132 <400> 271 gccctgcatg atggggtagt gggggttgtt gggcaggtac gagctgtgat caatcagcta 60 cactagtgaa gtccatatag tgagaaggga atcccacaac atg aaa ctt gct gtt 115 Met Lys Leu Ala Val 1 5 att ggt gga gat ggt atc ggc cca gag gtt act gca gaa gcc ctc aag 163 Ile Gly Gly Asp Gly Ile Gly Pro Glu Val Thr Ala Glu Ala Leu Lys 10 15 20 gtt cta aac gct gtc cgc gac gac atc gag acc acc gat tat gac ctt 211 Val Leu Asn Ala Val Arg Asp Asp Ile Glu Thr Thr Asp Tyr Asp Leu 25 30 35 ggc gca cgc cgt tac ctc aaa aat ggc gag ctg ctc acc gac gag gat 259 Gly Ala Arg Arg Tyr Leu Lys Asn Gly Glu Leu Leu Thr Asp Glu Asp 40 45 50 ctg gca tcc ctg cgc gag cat gac gcg atc ctt ctt ggc gct atc ggt 307 Leu Ala Ser Leu Arg Glu His Asp Ala Ile Leu Leu Gly Ala Ile Gly 55 60 65 gca cca ggt tcc gtc cct cca gga att ctc gag cgt ggt ttg ctg ctg 355 Ala Pro Gly Ser Val Pro Pro Gly Ile Leu Glu Arg Gly Leu Leu Leu 70 75 80 85 aag atg cga ttc gca ctg gat cac cac gtg aac ctg cgc cca tcc aag 403 Lys Met Arg Phe Ala Leu Asp His His Val Asn Leu Arg Pro Ser Lys 90 95 100 <210> 272 <211> 101 <212> PRT <213> Corynebacterium glutamicum <400> 272 Met Lys Leu Ala Val Ile Gly Gly Asp Gly Ile Gly Pro Glu Val Thr 1 5 10 15 Ala Glu Ala Leu Lys Val Leu Asn Ala Val Arg Asp Asp Ile Glu Thr 20 25 30 Thr Asp Tyr Asp Leu Gly Ala Arg Arg Tyr Leu Lys Asn Gly Glu Leu 35 40 45 Leu Thr Asp Glu Asp Leu Ala Ser Leu Arg Glu His Asp Ala Ile Leu 50 55 60 Leu Gly Ala Ile Gly Ala Pro Gly Ser Val Pro Pro Gly Ile Leu Glu 65 70 75 80 Arg Gly Leu Leu Leu Lys Met Arg Phe Ala Leu Asp His His Val Asn 85 90 95 Leu Arg Pro Ser Lys 100 <210> 273 <211> 1494 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1471) <223> RXN00536 <400> 273 cggcgggtcc cagaggtctt aacacgaccg gcatcccgtc gcggagtttg gtgttgccgg 60 tcgtggaccc acccaaaact ttttaagaag gttgaacaca atg tct cct aac gat 115 Met Ser Pro Asn Asp 1 5 gca ttc atc tcc gca cct gcc aag atc gaa acc cca gtt ggg cct cgc 163 Ala Phe Ile Ser Ala Pro Ala Lys Ile Glu Thr Pro Val Gly Pro Arg 10 15 20 aac gaa ggc cag cca gca tgg aat aag cag cgt ggc tcc tca atg cca 211 Asn Glu Gly Gln Pro Ala Trp Asn Lys Gln Arg Gly Ser Ser Met Pro 25 30 35 gtt aac cgc tac atg cct ttc gag gtt gag gta gaa gat att tct ctg 259 Val Asn Arg Tyr Met Pro Phe Glu Val Glu Val Glu Asp Ile Ser Leu 40 45 50 ccg gac cgc act tgg cca gat aaa aaa atc acc gtt gca cct cag tgg 307 Pro Asp Arg Thr Trp Pro Asp Lys Lys Ile Thr Val Ala Pro Gln Trp 55 60 65 tgt gct gtt gac ctg cgt gac ggc aac cag gct ctg att gat ccg atg 355 Cys Ala Val Asp Leu Arg Asp Gly Asn Gln Ala Leu Ile Asp Pro Met 70 75 80 85 tct cct gag cgt aag cgc cgc atg ttt gag ctg ctg gtt cag atg ggc 403 Ser Pro Glu Arg Lys Arg Arg Met Phe Glu Leu Leu Val Gln Met Gly 90 95 100 ttc aaa gaa atc gag gtc ggt ttc cct tca gct tcc cag act gat ttt 451 Phe Lys Glu Ile Glu Val Gly Phe Pro Ser Ala Ser Gln Thr Asp Phe 105 110 115 gat ttc gtt cgt gag atc atc gaa aag ggc atg atc cct gac gat gtc 499 Asp Phe Val Arg Glu Ile Ile Glu Lys Gly Met Ile Pro Asp Asp Val 120 125 130 acc att cag gtt ctg gtt cag gct cgt gag cac ctg att cgc cgt act 547 Thr Ile Gln Val Leu Val Gln Ala Arg Glu His Leu Ile Arg Arg Thr 135 140 145 ttt gaa gct tgc gaa ggc gca aaa aac gtt atc gtg cac ttc tac aac 595 Phe Glu Ala Cys Glu Gly Ala Lys Asn Val Ile Val His Phe Tyr Asn 150 155 160 165 tcc acc tcc atc ctg cag cgc aac gtg gtg ttc cgc atg gac aag gtg 643 Ser Thr Ser Ile Leu Gln Arg Asn Val Val Phe Arg Met Asp Lys Val 170 175 180 cag gtg aag aag ctg gct acc gat gcc gct gaa cta atc aag acc atc 691 Gln Val Lys Lys Leu Ala Thr Asp Ala Ala Glu Leu Ile Lys Thr Ile 185 190 195 gct cag gat tac cca gac acc aac tgg cgc tgg cag tac tcc cct gag 739 Ala Gln Asp Tyr Pro Asp Thr Asn Trp Arg Trp Gln Tyr Ser Pro Glu 200 205 210 tcc ttc acc ggc act gag gtt gag tac gcc aag gaa gtt gtg gac gca 787 Ser Phe Thr Gly Thr Glu Val Glu Tyr Ala Lys Glu Val Val Asp Ala 215 220 225 gtt gtt gag gtc atg gat cca act cct gag aac cca atg atc atc aac 835 Val Val Glu Val Met Asp Pro Thr Pro Glu Asn Pro Met Ile Ile Asn 230 235 240 245 ctg cct tcc acc gtt gag atg atc acc cct aac gtt tac gca gac tcc 883 Leu Pro Ser Thr Val Glu Met Ile Thr Pro Asn Val Tyr Ala Asp Ser 250 255 260 att gaa tgg atg cac cgc aat cta aac cgt cgt gat tcc att atc ctg 931 Ile Glu Trp Met His Arg Asn Leu Asn Arg Arg Asp Ser Ile Ile Leu 265 270 275 tcc ctg cac ccg cac aat gac cgt ggc acc ggc gtt ggc gca gct gag 979 Ser Leu His Pro His Asn Asp Arg Gly Thr Gly Val Gly Ala Ala Glu 280 285 290 ctg ggc tac atg gct ggc gct gac cgc atc gaa ggc tgc ctg ttc ggc 1027 Leu Gly Tyr Met Ala Gly Ala Asp Arg Ile Glu Gly Cys Leu Phe Gly 295 300 305 aac ggc gag cgc acc ggc aac gtc tgc ctg gtc acc ctg gca ctg aac 1075 Asn Gly Glu Arg Thr Gly Asn Val Cys Leu Val Thr Leu Ala Leu Asn 310 315 320 325 atg ctg acc cag ggc gtt gac cct cag ctg gac ttc acc gat ata cgc 1123 Met Leu Thr Gln Gly Val Asp Pro Gln Leu Asp Phe Thr Asp Ile Arg 330 335 340 cag atc cgc agc acc gtt gaa tac tgc aac cag ctg cgc gtt cct gag 1171 Gln Ile Arg Ser Thr Val Glu Tyr Cys Asn Gln Leu Arg Val Pro Glu 345 350 355 cgc cac cca tac ggc ggt gac ctg gtc ttc acc gct ttc tcc ggt tcc 1219 Arg His Pro Tyr Gly Gly Asp Leu Val Phe Thr Ala Phe Ser Gly Ser 360 365 370 cac cag gac gct gtg aac aag ggt ctg gac gcc atg gct gcc aag gtt 1267 His Gln Asp Ala Val Asn Lys Gly Leu Asp Ala Met Ala Ala Lys Val 375 380 385 cag cca ggt gct agc tcc act gaa gtt tct tgg gag cag ctg cgc gac 1315 Gln Pro Gly Ala Ser Ser Thr Glu Val Ser Trp Glu Gln Leu Arg Asp 390 395 400 405 acc cga atg gga ggt tcc tta cct gcc tat cga tcc aaa gga tgt cgg 1363 Thr Arg Met Gly Gly Ser Leu Pro Ala Tyr Arg Ser Lys Gly Cys Arg 410 415 420 tcg cga cta cga ggc tgt tat ccg cgt gaa ctc cca gtc cgg caa ggg 1411 Ser Arg Leu Arg Gly Cys Tyr Pro Arg Glu Leu Pro Val Arg Gln Gly 425 430 435 cgg cgt tgc tta cat cat gaa gac cga tca cgg tct gca gat ccc tcg 1459 Arg Arg Cys Leu His His Glu Asp Arg Ser Arg Ser Ala Asp Pro Ser 440 445 450 ctc cat gca ggt tgagttctcc accgttgtcc aga 1494 Leu His Ala Gly 455 <210> 274 <211> 457 <212> PRT <213> Corynebacterium glutamicum <400> 274 Met Ser Pro Asn Asp Ala Phe Ile Ser Ala Pro Ala Lys Ile Glu Thr 1 5 10 15 Pro Val Gly Pro Arg Asn Glu Gly Gln Pro Ala Trp Asn Lys Gln Arg 20 25 30 Gly Ser Ser Met Pro Val Asn Arg Tyr Met Pro Phe Glu Val Glu Val 35 40 45 Glu Asp Ile Ser Leu Pro Asp Arg Thr Trp Pro Asp Lys Lys Ile Thr 50 55 60 Val Ala Pro Gln Trp Cys Ala Val Asp Leu Arg Asp Gly Asn Gln Ala 65 70 75 80 Leu Ile Asp Pro Met Ser Pro Glu Arg Lys Arg Arg Met Phe Glu Leu 85 90 95 Leu Val Gln Met Gly Phe Lys Glu Ile Glu Val Gly Phe Pro Ser Ala 100 105 110 Ser Gln Thr Asp Phe Asp Phe Val Arg Glu Ile Ile Glu Lys Gly Met 115 120 125 Ile Pro Asp Asp Val Thr Ile Gln Val Leu Val Gln Ala Arg Glu His 130 135 140 Leu Ile Arg Arg Thr Phe Glu Ala Cys Glu Gly Ala Lys Asn Val Ile 145 150 155 160 Val His Phe Tyr Asn Ser Thr Ser Ile Leu Gln Arg Asn Val Val Phe 165 170 175 Arg Met Asp Lys Val Gln Val Lys Lys Leu Ala Thr Asp Ala Ala Glu 180 185 190 Leu Ile Lys Thr Ile Ala Gln Asp Tyr Pro Asp Thr Asn Trp Arg Trp 195 200 205 Gln Tyr Ser Pro Glu Ser Phe Thr Gly Thr Glu Val Glu Tyr Ala Lys 210 215 220 Glu Val Val Asp Ala Val Val Glu Val Met Asp Pro Thr Pro Glu Asn 225 230 235 240 Pro Met Ile Ile Asn Leu Pro Ser Thr Val Glu Met Ile Thr Pro Asn 245 250 255 Val Tyr Ala Asp Ser Ile Glu Trp Met His Arg Asn Leu Asn Arg Arg 260 265 270 Asp Ser Ile Ile Leu Ser Leu His Pro His Asn Asp Arg Gly Thr Gly 275 280 285 Val Gly Ala Ala Glu Leu Gly Tyr Met Ala Gly Ala Asp Arg Ile Glu 290 295 300 Gly Cys Leu Phe Gly Asn Gly Glu Arg Thr Gly Asn Val Cys Leu Val 305 310 315 320 Thr Leu Ala Leu Asn Met Leu Thr Gln Gly Val Asp Pro Gln Leu Asp 325 330 335 Phe Thr Asp Ile Arg Gln Ile Arg Ser Thr Val Glu Tyr Cys Asn Gln 340 345 350 Leu Arg Val Pro Glu Arg His Pro Tyr Gly Gly Asp Leu Val Phe Thr 355 360 365 Ala Phe Ser Gly Ser His Gln Asp Ala Val Asn Lys Gly Leu Asp Ala 370 375 380 Met Ala Ala Lys Val Gln Pro Gly Ala Ser Ser Thr Glu Val Ser Trp 385 390 395 400 Glu Gln Leu Arg Asp Thr Arg Met Gly Gly Ser Leu Pro Ala Tyr Arg 405 410 415 Ser Lys Gly Cys Arg Ser Arg Leu Arg Gly Cys Tyr Pro Arg Glu Leu 420 425 430 Pro Val Arg Gln Gly Arg Arg Cys Leu His His Glu Asp Arg Ser Arg 435 440 445 Ser Ala Asp Pro Ser Leu His Ala Gly 450 455 <210> 275 <211> 1333 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1333) <223> FRXA00536 <400> 275 cggcgggtcc cagaggtctt aacacgaccg gcatcccgtc gcggagtttg gtgttgccgg 60 tcgtggaccc acccaaaact ttttaagaag gttgaacaca atg tct cct aac gat 115 Met Ser Pro Asn Asp 1 5 gca ttc atc tcc gca cct gcc aag atc gaa acc cca gtt ggg cct cgc 163 Ala Phe Ile Ser Ala Pro Ala Lys Ile Glu Thr Pro Val Gly Pro Arg 10 15 20 aac gaa ggc cag cca gca tgg aat aag cag cgt ggc tcc tca atg cca 211 Asn Glu Gly Gln Pro Ala Trp Asn Lys Gln Arg Gly Ser Ser Met Pro 25 30 35 gtt aac cgc tac atg cct ttc gag gtt gag gta gaa gat att tct ctg 259 Val Asn Arg Tyr Met Pro Phe Glu Val Glu Val Glu Asp Ile Ser Leu 40 45 50 ccg gac cgc act tgg cca gat aaa aaa atc acc gtt gca cct cag tgg 307 Pro Asp Arg Thr Trp Pro Asp Lys Lys Ile Thr Val Ala Pro Gln Trp 55 60 65 tgt gct gtt gac ctg cgt gac ggc aac cag gct ctg att gat ccg atg 355 Cys Ala Val Asp Leu Arg Asp Gly Asn Gln Ala Leu Ile Asp Pro Met 70 75 80 85 tct cct gag cgt aag cgc cgc atg ttt gag ctg ctg gtt cag atg ggc 403 Ser Pro Glu Arg Lys Arg Arg Met Phe Glu Leu Leu Val Gln Met Gly 90 95 100 ttc aaa gaa atc gag gtc ggt ttc cct tca gct tcc cag act gat ttt 451 Phe Lys Glu Ile Glu Val Gly Phe Pro Ser Ala Ser Gln Thr Asp Phe 105 110 115 gat ttc gtt cgt gag atc atc gaa aag ggc atg atc cct gac gat gtc 499 Asp Phe Val Arg Glu Ile Ile Glu Lys Gly Met Ile Pro Asp Asp Val 120 125 130 acc att cag gtt ctg gtt cag gct cgt gag cac ctg att cgc cgt act 547 Thr Ile Gln Val Leu Val Gln Ala Arg Glu His Leu Ile Arg Arg Thr 135 140 145 ttt gaa gct tgc gaa ggc gca aaa aac gtt atc gtg cac ttc tac aac 595 Phe Glu Ala Cys Glu Gly Ala Lys Asn Val Ile Val His Phe Tyr Asn 150 155 160 165 tcc acc tcc atc ctg cag cgc aac gtg gtg ttc cgc atg gac aag gtg 643 Ser Thr Ser Ile Leu Gln Arg Asn Val Val Phe Arg Met Asp Lys Val 170 175 180 cag gtg aag aag ctg gct acc gat gcc gct gaa cta atc aag acc atc 691 Gln Val Lys Lys Leu Ala Thr Asp Ala Ala Glu Leu Ile Lys Thr Ile 185 190 195 gct cag gat tac cca gac acc aac tgg cgc tgg cag tac tcc cct gag 739 Ala Gln Asp Tyr Pro Asp Thr Asn Trp Arg Trp Gln Tyr Ser Pro Glu 200 205 210 tcc ttc acc ggc act gag gtt gag tac gcc aag gaa gtt gtg gac gca 787 Ser Phe Thr Gly Thr Glu Val Glu Tyr Ala Lys Glu Val Val Asp Ala 215 220 225 gtt gtt gag gtc atg gat cca act cct gag aac cca atg atc atc aac 835 Val Val Glu Val Met Asp Pro Thr Pro Glu Asn Pro Met Ile Ile Asn 230 235 240 245 ctg cct tcc acc gtt gag atg atc acc cct aac gtt tac gca gac tcc 883 Leu Pro Ser Thr Val Glu Met Ile Thr Pro Asn Val Tyr Ala Asp Ser 250 255 260 att gaa tgg atg cac cgc aat cta aac cgt cgt gat tcc att atc ctg 931 Ile Glu Trp Met His Arg Asn Leu Asn Arg Arg Asp Ser Ile Ile Leu 265 270 275 tcc ctg cac ccg cac aat gac cgt ggc acc ggc gtt ggc gca gct gag 979 Ser Leu His Pro His Asn Asp Arg Gly Thr Gly Val Gly Ala Ala Glu 280 285 290 ctg ggc tac atg gct ggc gct gac cgc atc gaa ggc tgc ctg ttc ggc 1027 Leu Gly Tyr Met Ala Gly Ala Asp Arg Ile Glu Gly Cys Leu Phe Gly 295 300 305 aac ggc gag cgc acc ggc aac gtc tgc ctg gtc acc ctg gca ctg aac 1075 Asn Gly Glu Arg Thr Gly Asn Val Cys Leu Val Thr Leu Ala Leu Asn 310 315 320 325 atg ctg acc cag ggc gtt gac cct cag ctg gac ttc acc gat ata cgc 1123 Met Leu Thr Gln Gly Val Asp Pro Gln Leu Asp Phe Thr Asp Ile Arg 330 335 340 cag atc cgc agc acc gtt gaa tac tgc aac cag ctg cgc gtt cct gag 1171 Gln Ile Arg Ser Thr Val Glu Tyr Cys Asn Gln Leu Arg Val Pro Glu 345 350 355 cgc cac cca tac ggc ggt gac ctg gtc ttc acc gct ttc tcc ggt tcc 1219 Arg His Pro Tyr Gly Gly Asp Leu Val Phe Thr Ala Phe Ser Gly Ser 360 365 370 cac cag gac gct gtg aac aag ggt ctg gac gcc atg gct gcc aag gtt 1267 His Gln Asp Ala Val Asn Lys Gly Leu Asp Ala Met Ala Ala Lys Val 375 380 385 cag cca ggt gct agc tcc act gaa gtt tct tgg gag cag ctg cgc gac 1315 Gln Pro Gly Ala Ser Ser Thr Glu Val Ser Trp Glu Gln Leu Arg Asp 390 395 400 405 acc gaa tgg gag gtt cct 1333 Thr Glu Trp Glu Val Pro 410 <210> 276 <211> 411 <212> PRT <213> Corynebacterium glutamicum <400> 276 Met Ser Pro Asn Asp Ala Phe Ile Ser Ala Pro Ala Lys Ile Glu Thr 1 5 10 15 Pro Val Gly Pro Arg Asn Glu Gly Gln Pro Ala Trp Asn Lys Gln Arg 20 25 30 Gly Ser Ser Met Pro Val Asn Arg Tyr Met Pro Phe Glu Val Glu Val 35 40 45 Glu Asp Ile Ser Leu Pro Asp Arg Thr Trp Pro Asp Lys Lys Ile Thr 50 55 60 Val Ala Pro Gln Trp Cys Ala Val Asp Leu Arg Asp Gly Asn Gln Ala 65 70 75 80 Leu Ile Asp Pro Met Ser Pro Glu Arg Lys Arg Arg Met Phe Glu Leu 85 90 95 Leu Val Gln Met Gly Phe Lys Glu Ile Glu Val Gly Phe Pro Ser Ala 100 105 110 Ser Gln Thr Asp Phe Asp Phe Val Arg Glu Ile Ile Glu Lys Gly Met 115 120 125 Ile Pro Asp Asp Val Thr Ile Gln Val Leu Val Gln Ala Arg Glu His 130 135 140 Leu Ile Arg Arg Thr Phe Glu Ala Cys Glu Gly Ala Lys Asn Val Ile 145 150 155 160 Val His Phe Tyr Asn Ser Thr Ser Ile Leu Gln Arg Asn Val Val Phe 165 170 175 Arg Met Asp Lys Val Gln Val Lys Lys Leu Ala Thr Asp Ala Ala Glu 180 185 190 Leu Ile Lys Thr Ile Ala Gln Asp Tyr Pro Asp Thr Asn Trp Arg Trp 195 200 205 Gln Tyr Ser Pro Glu Ser Phe Thr Gly Thr Glu Val Glu Tyr Ala Lys 210 215 220 Glu Val Val Asp Ala Val Val Glu Val Met Asp Pro Thr Pro Glu Asn 225 230 235 240 Pro Met Ile Ile Asn Leu Pro Ser Thr Val Glu Met Ile Thr Pro Asn 245 250 255 Val Tyr Ala Asp Ser Ile Glu Trp Met His Arg Asn Leu Asn Arg Arg 260 265 270 Asp Ser Ile Ile Leu Ser Leu His Pro His Asn Asp Arg Gly Thr Gly 275 280 285 Val Gly Ala Ala Glu Leu Gly Tyr Met Ala Gly Ala Asp Arg Ile Glu 290 295 300 Gly Cys Leu Phe Gly Asn Gly Glu Arg Thr Gly Asn Val Cys Leu Val 305 310 315 320 Thr Leu Ala Leu Asn Met Leu Thr Gln Gly Val Asp Pro Gln Leu Asp 325 330 335 Phe Thr Asp Ile Arg Gln Ile Arg Ser Thr Val Glu Tyr Cys Asn Gln 340 345 350 Leu Arg Val Pro Glu Arg His Pro Tyr Gly Gly Asp Leu Val Phe Thr 355 360 365 Ala Phe Ser Gly Ser His Gln Asp Ala Val Asn Lys Gly Leu Asp Ala 370 375 380 Met Ala Ala Lys Val Gln Pro Gly Ala Ser Ser Thr Glu Val Ser Trp 385 390 395 400 Glu Gln Leu Arg Asp Thr Glu Trp Glu Val Pro 405 410 <210> 277 <211> 714 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(691) <223> RXN02965 <400> 277 caggaggccg cacccacctg gtatccccag cagtcgcagc cgccaccgaa tccgcggacc 60 ctgtcctcac ctgcagatat ctaaggaagg ctagaaaaca atg gaa aaa ttt acc 115 Met Glu Lys Phe Thr 1 5 acc tac acc ggc gtt ggc gtt cca ctg cag cga tcc aac gtg gac acc 163 Thr Tyr Thr Gly Val Gly Val Pro Leu Gln Arg Ser Asn Val Asp Thr 10 15 20 gac cag atc atc cca gcc gtc tac ctc aag cgc gtc acc cgg acc ggc 211 Asp Gln Ile Ile Pro Ala Val Tyr Leu Lys Arg Val Thr Arg Thr Gly 25 30 35 ttc gaa gac gga ctg ttt tcc aac tgg cgc caa aac gac ccc aac ttt 259 Phe Glu Asp Gly Leu Phe Ser Asn Trp Arg Gln Asn Asp Pro Asn Phe 40 45 50 gtc ctc aac acc gac acc tac aag aac ggc tcc gtt ctc gta gca ggc 307 Val Leu Asn Thr Asp Thr Tyr Lys Asn Gly Ser Val Leu Val Ala Gly 55 60 65 cct gac ttt ggc acc ggc tcc tcc cgc gag cac gcc gtc tgg gca ctc 355 Pro Asp Phe Gly Thr Gly Ser Ser Arg Glu His Ala Val Trp Ala Leu 70 75 80 85 atg gac tac ggc ttc cgc gct gtc ttc tcc tca cga ttc gcc gac atc 403 Met Asp Tyr Gly Phe Arg Ala Val Phe Ser Ser Arg Phe Ala Asp Ile 90 95 100 ttc cgc ggc aac tcc gga aaa gcg ggc atg ctc acc ggc atc atg gaa 451 Phe Arg Gly Asn Ser Gly Lys Ala Gly Met Leu Thr Gly Ile Met Glu 105 110 115 cag tcc gac atc gaa ctt ctg tgg aag ctc atg gaa caa acc cca ggc 499 Gln Ser Asp Ile Glu Leu Leu Trp Lys Leu Met Glu Gln Thr Pro Gly 120 125 130 ctc gaa ctg acc gtg aac ctg gaa aag cag atc gtc acc gca ggc gac 547 Leu Glu Leu Thr Val Asn Leu Glu Lys Gln Ile Val Thr Ala Gly Asp 135 140 145 gta gtg atc agc ttc gaa gtt gac ccc tac atc cgc tgg cgt ttg atg 595 Val Val Ile Ser Phe Glu Val Asp Pro Tyr Ile Arg Trp Arg Leu Met 150 155 160 165 gaa ggc ctc gac gac gct ggc ctg acc ctg cgc aag ctc gat gaa att 643 Glu Gly Leu Asp Asp Ala Gly Leu Thr Leu Arg Lys Leu Asp Glu Ile 170 175 180 gaa gac tac gag gct aag cgc cct gcg ttt aag cca cgc act aac gct 691 Glu Asp Tyr Glu Ala Lys Arg Pro Ala Phe Lys Pro Arg Thr Asn Ala 185 190 195 taagtttcag tctgatagcg aaa 714 <210> 278 <211> 197 <212> PRT <213> Corynebacterium glutamicum <400> 278 Met Glu Lys Phe Thr Thr Tyr Thr Gly Val Gly Val Pro Leu Gln Arg 1 5 10 15 Ser Asn Val Asp Thr Asp Gln Ile Ile Pro Ala Val Tyr Leu Lys Arg 20 25 30 Val Thr Arg Thr Gly Phe Glu Asp Gly Leu Phe Ser Asn Trp Arg Gln 35 40 45 Asn Asp Pro Asn Phe Val Leu Asn Thr Asp Thr Tyr Lys Asn Gly Ser 50 55 60 Val Leu Val Ala Gly Pro Asp Phe Gly Thr Gly Ser Ser Arg Glu His 65 70 75 80 Ala Val Trp Ala Leu Met Asp Tyr Gly Phe Arg Ala Val Phe Ser Ser 85 90 95 Arg Phe Ala Asp Ile Phe Arg Gly Asn Ser Gly Lys Ala Gly Met Leu 100 105 110 Thr Gly Ile Met Glu Gln Ser Asp Ile Glu Leu Leu Trp Lys Leu Met 115 120 125 Glu Gln Thr Pro Gly Leu Glu Leu Thr Val Asn Leu Glu Lys Gln Ile 130 135 140 Val Thr Ala Gly Asp Val Val Ile Ser Phe Glu Val Asp Pro Tyr Ile 145 150 155 160 Arg Trp Arg Leu Met Glu Gly Leu Asp Asp Ala Gly Leu Thr Leu Arg 165 170 175 Lys Leu Asp Glu Ile Glu Asp Tyr Glu Ala Lys Arg Pro Ala Phe Lys 180 185 190 Pro Arg Thr Asn Ala 195 <210> 279 <211> 936 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(913) <223> RXN01929 <400> 279 aaaatttgac tccataacga gaacttaatc gagcaacacc cctgaacagt gaatcaaatc 60 ggaatttatt tattctgagc tggtcatcac atctatactc atg ccc atg tca ggc 115 Met Pro Met Ser Gly 1 5 att gat gca aag aaa atc cgc acc cgt cat ttc cgc gaa gct aaa gta 163 Ile Asp Ala Lys Lys Ile Arg Thr Arg His Phe Arg Glu Ala Lys Val 10 15 20 aac ggc cag aaa gtt tcg gtt ctc acc agc tat gat gcg ctt tcg gcg 211 Asn Gly Gln Lys Val Ser Val Leu Thr Ser Tyr Asp Ala Leu Ser Ala 25 30 35 cgc att ttt gat gag gct ggc gtc gat atg ctc ctt gtt ggt gat tcc 259 Arg Ile Phe Asp Glu Ala Gly Val Asp Met Leu Leu Val Gly Asp Ser 40 45 50 gct gcc aac gtt gtg ctg ggt cgc gat acc acc ttg tcg atc acc ttg 307 Ala Ala Asn Val Val Leu Gly Arg Asp Thr Thr Leu Ser Ile Thr Leu 55 60 65 gat gag atg att gtg ctg gcc aag gcg gtg acg atc gct acg aag cgt 355 Asp Glu Met Ile Val Leu Ala Lys Ala Val Thr Ile Ala Thr Lys Arg 70 75 80 85 gcg ctt gtg gtg gtt gat ctg ccg ttt ggt acc tat gag gtg agc cca 403 Ala Leu Val Val Val Asp Leu Pro Phe Gly Thr Tyr Glu Val Ser Pro 90 95 100 aat cag gcg gtg gag tcc gcg atc cgg gtc atg cgt gaa acg ggt gcg 451 Asn Gln Ala Val Glu Ser Ala Ile Arg Val Met Arg Glu Thr Gly Ala 105 110 115 gct gcg gtg aag atc gag ggt ggc gtg gag atc gcg cag acg att cga 499 Ala Ala Val Lys Ile Glu Gly Gly Val Glu Ile Ala Gln Thr Ile Arg 120 125 130 cgc att gtt gat gct gga att ccg gtt gtc ggc cac atc ggg tac acc 547 Arg Ile Val Asp Ala Gly Ile Pro Val Val Gly His Ile Gly Tyr Thr 135 140 145 ccg cag tcc gag cat tcc ttg ggc ggc cac gtg gtt cag ggt cgt ggc 595 Pro Gln Ser Glu His Ser Leu Gly Gly His Val Val Gln Gly Arg Gly 150 155 160 165 gcg agt tct gga aag ctc atc gcc gat gcc cgc gcg ttg gag cag gcg 643 Ala Ser Ser Gly Lys Leu Ile Ala Asp Ala Arg Ala Leu Glu Gln Ala 170 175 180 ggt gcg ttt gcg gtt gtg ttg gag atg gtt cca gca gag gca gcg cgc 691 Gly Ala Phe Ala Val Val Leu Glu Met Val Pro Ala Glu Ala Ala Arg 185 190 195 gag gtt acc gag gat ctt tcc atc acc act atc gga atc ggt gcc ggc 739 Glu Val Thr Glu Asp Leu Ser Ile Thr Thr Ile Gly Ile Gly Ala Gly 200 205 210 aat ggc aca gat ggg cag gtt ttg gtg tgg cag gat gcc ttc ggc ctc 787 Asn Gly Thr Asp Gly Gln Val Leu Val Trp Gln Asp Ala Phe Gly Leu 215 220 225 aac cgc ggc aag aag cca cgc ttc gtc cgc gag tac gcc acc ttg ggc 835 Asn Arg Gly Lys Lys Pro Arg Phe Val Arg Glu Tyr Ala Thr Leu Gly 230 235 240 245 gat tcc ttg cac gac gcc gcg cag gcc tac atc gcc gat atc cac gcg 883 Asp Ser Leu His Asp Ala Ala Gln Ala Tyr Ile Ala Asp Ile His Ala 250 255 260 ggt acc ttc cca ggc gaa gcg gag tcc ttt taatgcaggt agcaaccaca 933 Gly Thr Phe Pro Gly Glu Ala Glu Ser Phe 265 270 aag 936 <210> 280 <211> 271 <212> PRT <213> Corynebacterium glutamicum <400> 280 Met Pro Met Ser Gly Ile Asp Ala Lys Lys Ile Arg Thr Arg His Phe 1 5 10 15 Arg Glu Ala Lys Val Asn Gly Gln Lys Val Ser Val Leu Thr Ser Tyr 20 25 30 Asp Ala Leu Ser Ala Arg Ile Phe Asp Glu Ala Gly Val Asp Met Leu 35 40 45 Leu Val Gly Asp Ser Ala Ala Asn Val Val Leu Gly Arg Asp Thr Thr 50 55 60 Leu Ser Ile Thr Leu Asp Glu Met Ile Val Leu Ala Lys Ala Val Thr 65 70 75 80 Ile Ala Thr Lys Arg Ala Leu Val Val Val Asp Leu Pro Phe Gly Thr 85 90 95 Tyr Glu Val Ser Pro Asn Gln Ala Val Glu Ser Ala Ile Arg Val Met 100 105 110 Arg Glu Thr Gly Ala Ala Ala Val Lys Ile Glu Gly Gly Val Glu Ile 115 120 125 Ala Gln Thr Ile Arg Arg Ile Val Asp Ala Gly Ile Pro Val Val Gly 130 135 140 His Ile Gly Tyr Thr Pro Gln Ser Glu His Ser Leu Gly Gly His Val 145 150 155 160 Val Gln Gly Arg Gly Ala Ser Ser Gly Lys Leu Ile Ala Asp Ala Arg 165 170 175 Ala Leu Glu Gln Ala Gly Ala Phe Ala Val Val Leu Glu Met Val Pro 180 185 190 Ala Glu Ala Ala Arg Glu Val Thr Glu Asp Leu Ser Ile Thr Thr Ile 195 200 205 Gly Ile Gly Ala Gly Asn Gly Thr Asp Gly Gln Val Leu Val Trp Gln 210 215 220 Asp Ala Phe Gly Leu Asn Arg Gly Lys Lys Pro Arg Phe Val Arg Glu 225 230 235 240 Tyr Ala Thr Leu Gly Asp Ser Leu His Asp Ala Ala Gln Ala Tyr Ile 245 250 255 Ala Asp Ile His Ala Gly Thr Phe Pro Gly Glu Ala Glu Ser Phe 260 265 270 <210> 281 <211> 930 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(907) <223> FRXA01929 <400> 281 tgactccata acgagaactt aatcgagcaa cacccctgaa cagtgaatca aatcggaatt 60 tatttattct gagctggtca tcacatctat actcatgccc atg tca ggc att gat 115 Met Ser Gly Ile Asp 1 5 gca aag aaa atc cgc acc cgt cat ttc cgc gaa gct aaa gta aac ggc 163 Ala Lys Lys Ile Arg Thr Arg His Phe Arg Glu Ala Lys Val Asn Gly 10 15 20 cag aaa gtt tcg gtt ctc acc agc tat gat gcg ctt tcg gcg cgc att 211 Gln Lys Val Ser Val Leu Thr Ser Tyr Asp Ala Leu Ser Ala Arg Ile 25 30 35 ttt gat gag gct ggc gtc gat atg ctc ctt gtt ggt gat tcc gct gcc 259 Phe Asp Glu Ala Gly Val Asp Met Leu Leu Val Gly Asp Ser Ala Ala 40 45 50 aac gtt gtg ctg ggt cgc gat acc acc ttg tcg atc acc ttg gat gag 307 Asn Val Val Leu Gly Arg Asp Thr Thr Leu Ser Ile Thr Leu Asp Glu 55 60 65 atg att gtg ctg gcc aag gcg gtg acg atc gct acg aag cgt gcg ctt 355 Met Ile Val Leu Ala Lys Ala Val Thr Ile Ala Thr Lys Arg Ala Leu 70 75 80 85 gtg gtg gtt gat ctg ccg ttt ggt acc tat gag gtg agc cca aat cag 403 Val Val Val Asp Leu Pro Phe Gly Thr Tyr Glu Val Ser Pro Asn Gln 90 95 100 gcg gtg gag tcc gcg atc cgg gtc atg cgt gaa acg ggt gcg gct gcg 451 Ala Val Glu Ser Ala Ile Arg Val Met Arg Glu Thr Gly Ala Ala Ala 105 110 115 gtg aag atc gag ggt ggc gtg gag atc gcg cag acg att cga cgc att 499 Val Lys Ile Glu Gly Gly Val Glu Ile Ala Gln Thr Ile Arg Arg Ile 120 125 130 gtt gat gct gga att ccg gtt gtc ggc cac atc ggg tac acc ccg cag 547 Val Asp Ala Gly Ile Pro Val Val Gly His Ile Gly Tyr Thr Pro Gln 135 140 145 tcc gag cat tcc ttg ggc ggc cac gtg gtt cag ggt cgt ggc gcg agt 595 Ser Glu His Ser Leu Gly Gly His Val Val Gln Gly Arg Gly Ala Ser 150 155 160 165 tct gga aag ctc atc gcc gat gcc cgc gcg ttg gag cag gcg ggt gcg 643 Ser Gly Lys Leu Ile Ala Asp Ala Arg Ala Leu Glu Gln Ala Gly Ala 170 175 180 ttt gcg gtt gtg ttg gag atg gtt cca gca gag gca gcg cgc gag gtt 691 Phe Ala Val Val Leu Glu Met Val Pro Ala Glu Ala Ala Arg Glu Val 185 190 195 acc gag gat ctt tcc atc acc act atc gga atc ggt gcc ggc aat ggc 739 Thr Glu Asp Leu Ser Ile Thr Thr Ile Gly Ile Gly Ala Gly Asn Gly 200 205 210 aca gat ggg cag gtt ttg gtg tgg cag gat gcc ttc ggc ctc aac cgc 787 Thr Asp Gly Gln Val Leu Val Trp Gln Asp Ala Phe Gly Leu Asn Arg 215 220 225 ggc aag aag cca cgc ttc gtc cgc gag tac gcc acc ttg ggc gat tcc 835 Gly Lys Lys Pro Arg Phe Val Arg Glu Tyr Ala Thr Leu Gly Asp Ser 230 235 240 245 ttg cac gac gcc gcg cag gcc tac atc gcc gat atc cac gcg ggt acc 883 Leu His Asp Ala Ala Gln Ala Tyr Ile Ala Asp Ile His Ala Gly Thr 250 255 260 ttc cca ggc gaa gcg gag tcc ttt taatgcaggt agcaaccaca aag 930 Phe Pro Gly Glu Ala Glu Ser Phe 265 <210> 282 <211> 269 <212> PRT <213> Corynebacterium glutamicum <400> 282 Met Ser Gly Ile Asp Ala Lys Lys Ile Arg Thr Arg His Phe Arg Glu 1 5 10 15 Ala Lys Val Asn Gly Gln Lys Val Ser Val Leu Thr Ser Tyr Asp Ala 20 25 30 Leu Ser Ala Arg Ile Phe Asp Glu Ala Gly Val Asp Met Leu Leu Val 35 40 45 Gly Asp Ser Ala Ala Asn Val Val Leu Gly Arg Asp Thr Thr Leu Ser 50 55 60 Ile Thr Leu Asp Glu Met Ile Val Leu Ala Lys Ala Val Thr Ile Ala 65 70 75 80 Thr Lys Arg Ala Leu Val Val Val Asp Leu Pro Phe Gly Thr Tyr Glu 85 90 95 Val Ser Pro Asn Gln Ala Val Glu Ser Ala Ile Arg Val Met Arg Glu 100 105 110 Thr Gly Ala Ala Ala Val Lys Ile Glu Gly Gly Val Glu Ile Ala Gln 115 120 125 Thr Ile Arg Arg Ile Val Asp Ala Gly Ile Pro Val Val Gly His Ile 130 135 140 Gly Tyr Thr Pro Gln Ser Glu His Ser Leu Gly Gly His Val Val Gln 145 150 155 160 Gly Arg Gly Ala Ser Ser Gly Lys Leu Ile Ala Asp Ala Arg Ala Leu 165 170 175 Glu Gln Ala Gly Ala Phe Ala Val Val Leu Glu Met Val Pro Ala Glu 180 185 190 Ala Ala Arg Glu Val Thr Glu Asp Leu Ser Ile Thr Thr Ile Gly Ile 195 200 205 Gly Ala Gly Asn Gly Thr Asp Gly Gln Val Leu Val Trp Gln Asp Ala 210 215 220 Phe Gly Leu Asn Arg Gly Lys Lys Pro Arg Phe Val Arg Glu Tyr Ala 225 230 235 240 Thr Leu Gly Asp Ser Leu His Asp Ala Ala Gln Ala Tyr Ile Ala Asp 245 250 255 Ile His Ala Gly Thr Phe Pro Gly Glu Ala Glu Ser Phe 260 265 <210> 283 <211> 1065 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1042) <223> RXN01420 <400> 283 cgaagttcac gactacaggc attacctggg tgctgatttt gcgcgagtaa agctgtggct 60 gcggaatgcg ctgctcatcc acacgtggaa tcctgattgg gtg acg ctg ggt gga 115 Val Thr Leu Gly Gly 1 5 ttg aat gta cca tcg tgg tcg ctg ggc gcg gaa atg ctg ttc tac ctg 163 Leu Asn Val Pro Ser Trp Ser Leu Gly Ala Glu Met Leu Phe Tyr Leu 10 15 20 acg ttc ccg ctg ttt att ccg tta gtg cgc aaa gtg aag ggc gtg ggc 211 Thr Phe Pro Leu Phe Ile Pro Leu Val Arg Lys Val Lys Gly Val Gly 25 30 35 aac tgg tgg gca ttt ggc atc acc ttt gcc gtg agc ctg gcg ctg att 259 Asn Trp Trp Ala Phe Gly Ile Thr Phe Ala Val Ser Leu Ala Leu Ile 40 45 50 aca gtg att cac ttt tat gcg gac gga cca aag ggg att gag aac ttc 307 Thr Val Ile His Phe Tyr Ala Asp Gly Pro Lys Gly Ile Glu Asn Phe 55 60 65 ttt gtt cct cgc ctg tgg gac acc aat gtg tca ccg gtc gcg gaa gtt 355 Phe Val Pro Arg Leu Trp Asp Thr Asn Val Ser Pro Val Ala Glu Val 70 75 80 85 cac gcc gat cca gtg tgg ttt atg cag gaa gaa att ccc gtg ctg gaa 403 His Ala Asp Pro Val Trp Phe Met Gln Glu Glu Ile Pro Val Leu Glu 90 95 100 tct tac tgg ctg tct tac tac ttc ccg ctg acc aga ctc atc gag ttc 451 Ser Tyr Trp Leu Ser Tyr Tyr Phe Pro Leu Thr Arg Leu Ile Glu Phe 105 110 115 tac ctc ggt gtg ttt ggc gcg aag ctg gtt gct gaa ggc atg ttt aaa 499 Tyr Leu Gly Val Phe Gly Ala Lys Leu Val Ala Glu Gly Met Phe Lys 120 125 130 aac acc aac atc acc atc ccg ctg atc gca ctg gct gtt tct ttt gtt 547 Asn Thr Asn Ile Thr Ile Pro Leu Ile Ala Leu Ala Val Ser Phe Val 135 140 145 gct act tgg ttt gtg cca ctg gca ttc aag atg tct gtc atc atg tcc 595 Ala Thr Trp Phe Val Pro Leu Ala Phe Lys Met Ser Val Ile Met Ser 150 155 160 165 ctg cca atg gct ttt gtt gtg gca acg ctt gcg gtg aga gac att gaa 643 Leu Pro Met Ala Phe Val Val Ala Thr Leu Ala Val Arg Asp Ile Glu 170 175 180 ggc aag agt ggg gaa atc gcc tcg cct cgc gca gtt ttg ttg ggt aat 691 Gly Lys Ser Gly Glu Ile Ala Ser Pro Arg Ala Val Leu Leu Gly Asn 185 190 195 att tcc ttt gcc ttc tac atg gtg caa ttc ccc gtc atg gtg ttt gtg 739 Ile Ser Phe Ala Phe Tyr Met Val Gln Phe Pro Val Met Val Phe Val 200 205 210 cag cgc tat ttc att gct ggc aaa gaa tac ggc ttc ctt ggc tgg gca 787 Gln Arg Tyr Phe Ile Ala Gly Lys Glu Tyr Gly Phe Leu Gly Trp Ala 215 220 225 ttc tat gca gtg gtg tgt ttc atc gtg tcg gtc att ctc gcg tgg gtg 835 Phe Tyr Ala Val Val Cys Phe Ile Val Ser Val Ile Leu Ala Trp Val 230 235 240 245 ctg ttt acc ttc gtt gat gat cct ttg atg aag gcc acg gcg cgc aag 883 Leu Phe Thr Phe Val Asp Asp Pro Leu Met Lys Ala Thr Ala Arg Lys 250 255 260 aag ggg agt agg cgc ttg aag cag tcc aat att ttg gtc cgt gac ctg 931 Lys Gly Ser Arg Arg Leu Lys Gln Ser Asn Ile Leu Val Arg Asp Leu 265 270 275 aaa gtt ctc ttc ggc aaa agc ccc gaa aag ccg tta aaa gtt gag act 979 Lys Val Leu Phe Gly Lys Ser Pro Glu Lys Pro Leu Lys Val Glu Thr 280 285 290 cgc gct gag aat ctc aca gaa aac tcc gaa gct ccc gct aag gta gct 1027 Arg Ala Glu Asn Leu Thr Glu Asn Ser Glu Ala Pro Ala Lys Val Ala 295 300 305 acc gga atc aaa tct tagggaagga aaacatatgg cta 1065 Thr Gly Ile Lys Ser 310 <210> 284 <211> 314 <212> PRT <213> Corynebacterium glutamicum <400> 284 Val Thr Leu Gly Gly Leu Asn Val Pro Ser Trp Ser Leu Gly Ala Glu 1 5 10 15 Met Leu Phe Tyr Leu Thr Phe Pro Leu Phe Ile Pro Leu Val Arg Lys 20 25 30 Val Lys Gly Val Gly Asn Trp Trp Ala Phe Gly Ile Thr Phe Ala Val 35 40 45 Ser Leu Ala Leu Ile Thr Val Ile His Phe Tyr Ala Asp Gly Pro Lys 50 55 60 Gly Ile Glu Asn Phe Phe Val Pro Arg Leu Trp Asp Thr Asn Val Ser 65 70 75 80 Pro Val Ala Glu Val His Ala Asp Pro Val Trp Phe Met Gln Glu Glu 85 90 95 Ile Pro Val Leu Glu Ser Tyr Trp Leu Ser Tyr Tyr Phe Pro Leu Thr 100 105 110 Arg Leu Ile Glu Phe Tyr Leu Gly Val Phe Gly Ala Lys Leu Val Ala 115 120 125 Glu Gly Met Phe Lys Asn Thr Asn Ile Thr Ile Pro Leu Ile Ala Leu 130 135 140 Ala Val Ser Phe Val Ala Thr Trp Phe Val Pro Leu Ala Phe Lys Met 145 150 155 160 Ser Val Ile Met Ser Leu Pro Met Ala Phe Val Val Ala Thr Leu Ala 165 170 175 Val Arg Asp Ile Glu Gly Lys Ser Gly Glu Ile Ala Ser Pro Arg Ala 180 185 190 Val Leu Leu Gly Asn Ile Ser Phe Ala Phe Tyr Met Val Gln Phe Pro 195 200 205 Val Met Val Phe Val Gln Arg Tyr Phe Ile Ala Gly Lys Glu Tyr Gly 210 215 220 Phe Leu Gly Trp Ala Phe Tyr Ala Val Val Cys Phe Ile Val Ser Val 225 230 235 240 Ile Leu Ala Trp Val Leu Phe Thr Phe Val Asp Asp Pro Leu Met Lys 245 250 255 Ala Thr Ala Arg Lys Lys Gly Ser Arg Arg Leu Lys Gln Ser Asn Ile 260 265 270 Leu Val Arg Asp Leu Lys Val Leu Phe Gly Lys Ser Pro Glu Lys Pro 275 280 285 Leu Lys Val Glu Thr Arg Ala Glu Asn Leu Thr Glu Asn Ser Glu Ala 290 295 300 Pro Ala Lys Val Ala Thr Gly Ile Lys Ser 305 310 <210> 285 <211> 1137 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1114) <223> RXS01145 <400> 285 taatgtagtt gtctgcccaa gcgagttaaa ctcccacgat ttacagtggg gggcagacat 60 cttttcacca aaatttttac gaaaggcgag attttctccc atg gct att gaa ctg 115 Met Ala Ile Glu Leu 1 5 ctt tat gat gct gac gct gac ctc tcc ttg atc cag ggc cgt aag gtt 163 Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile Gln Gly Arg Lys Val 10 15 20 gcc atc gtt ggc tac ggc tcc cag ggc cac gca cac tcc cag aac ctc 211 Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala His Ser Gln Asn Leu 25 30 35 cgc gat tct ggc gtt gag gtt gtc att ggt ctg cgc gag ggc tcc aag 259 Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu Arg Glu Gly Ser Lys 40 45 50 tcc gca gag aag gca aag gaa gca ggc ttc gag gtc aag acc acc gct 307 Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu Val Lys Thr Thr Ala 55 60 65 gag gct gca gct tgg gct gac gtc atc atg ctc ctg gct cca gac acc 355 Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu Leu Ala Pro Asp Thr 70 75 80 85 tcc cag gca gaa atc ttc acc aac gac atc gag cca aac ctg aac gca 403 Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu Pro Asn Leu Asn Ala 90 95 100 ggc gac gca ctg ctg ttc ggc cac ggc ctg aac att cac ttc gac ctg 451 Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn Ile His Phe Asp Leu 105 110 115 atc aag cca gct gac gac atc atc gtt ggc atg gtt gcg cca aag ggc 499 Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met Val Ala Pro Lys Gly 120 125 130 cca ggc cac ttg gtt cgc cgt cag ttc gtt gat ggc aag ggt gtt cct 547 Pro Gly His Leu Val Arg Arg Gln Phe Val Asp Gly Lys Gly Val Pro 135 140 145 tgc ctc atc gca gtc gac cag gac cca acc gga acc gca cag gct ctg 595 Cys Leu Ile Ala Val Asp Gln Asp Pro Thr Gly Thr Ala Gln Ala Leu 150 155 160 165 acc ctg tcc tac gca gca gca atc ggt ggc gca cgc gca ggc gtt atc 643 Thr Leu Ser Tyr Ala Ala Ala Ile Gly Gly Ala Arg Ala Gly Val Ile 170 175 180 cca acc acc ttc gaa gct gag acc gtc acc gac ctc ttc ggc gag cag 691 Pro Thr Thr Phe Glu Ala Glu Thr Val Thr Asp Leu Phe Gly Glu Gln 185 190 195 gct gtt ctc tgc ggt ggc acc gag gaa ctg gtc aag gtt ggc ttc gag 739 Ala Val Leu Cys Gly Gly Thr Glu Glu Leu Val Lys Val Gly Phe Glu 200 205 210 gtt ctc acc gaa gct ggc tac gag cca gag atg gca tac ttc gag gtt 787 Val Leu Thr Glu Ala Gly Tyr Glu Pro Glu Met Ala Tyr Phe Glu Val 215 220 225 ctt cac gag ctc aag ctc atc gtt gac ctc atg ttc gaa ggt ggc atc 835 Leu His Glu Leu Lys Leu Ile Val Asp Leu Met Phe Glu Gly Gly Ile 230 235 240 245 agc aac atg aac tac tct gtt tct gac acc gct gag ttc ggt ggc tac 883 Ser Asn Met Asn Tyr Ser Val Ser Asp Thr Ala Glu Phe Gly Gly Tyr 250 255 260 ctc tcc ggc cca cgc gtc atc gat gca gac acc aag tcc cgc atg aag 931 Leu Ser Gly Pro Arg Val Ile Asp Ala Asp Thr Lys Ser Arg Met Lys 265 270 275 gac atc ctg acc gat atc cag gac ggc acc ttc acc aag cgc ctc atc 979 Asp Ile Leu Thr Asp Ile Gln Asp Gly Thr Phe Thr Lys Arg Leu Ile 280 285 290 gca aac gtt gag aac ggc aac acc gag ctt gag ggc ctt cgt gct tcc 1027 Ala Asn Val Glu Asn Gly Asn Thr Glu Leu Glu Gly Leu Arg Ala Ser 295 300 305 tac aac aac cac cca atc gag gag acc ggc gct aag ctc cgc gac ctc 1075 Tyr Asn Asn His Pro Ile Glu Glu Thr Gly Ala Lys Leu Arg Asp Leu 310 315 320 325 atg agc tgg gtc aag gtt gac gct cgc gca gaa acc gct taagtttcac 1124 Met Ser Trp Val Lys Val Asp Ala Arg Ala Glu Thr Ala 330 335 ccctttgacg gct 1137 <210> 286 <211> 338 <212> PRT <213> Corynebacterium glutamicum <400> 286 Met Ala Ile Glu Leu Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile 1 5 10 15 Gln Gly Arg Lys Val Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala 20 25 30 His Ser Gln Asn Leu Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu 35 40 45 Arg Glu Gly Ser Lys Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu 50 55 60 Val Lys Thr Thr Ala Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu 65 70 75 80 Leu Ala Pro Asp Thr Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu 85 90 95 Pro Asn Leu Asn Ala Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn 100 105 110 Ile His Phe Asp Leu Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met 115 120 125 Val Ala Pro Lys Gly Pro Gly His Leu Val Arg Arg Gln Phe Val Asp 130 135 140 Gly Lys Gly Val Pro Cys Leu Ile Ala Val Asp Gln Asp Pro Thr Gly 145 150 155 160 Thr Ala Gln Ala Leu Thr Leu Ser Tyr Ala Ala Ala Ile Gly Gly Ala 165 170 175 Arg Ala Gly Val Ile Pro Thr Thr Phe Glu Ala Glu Thr Val Thr Asp 180 185 190 Leu Phe Gly Glu Gln Ala Val Leu Cys Gly Gly Thr Glu Glu Leu Val 195 200 205 Lys Val Gly Phe Glu Val Leu Thr Glu Ala Gly Tyr Glu Pro Glu Met 210 215 220 Ala Tyr Phe Glu Val Leu His Glu Leu Lys Leu Ile Val Asp Leu Met 225 230 235 240 Phe Glu Gly Gly Ile Ser Asn Met Asn Tyr Ser Val Ser Asp Thr Ala 245 250 255 Glu Phe Gly Gly Tyr Leu Ser Gly Pro Arg Val Ile Asp Ala Asp Thr 260 265 270 Lys Ser Arg Met Lys Asp Ile Leu Thr Asp Ile Gln Asp Gly Thr Phe 275 280 285 Thr Lys Arg Leu Ile Ala Asn Val Glu Asn Gly Asn Thr Glu Leu Glu 290 295 300 Gly Leu Arg Ala Ser Tyr Asn Asn His Pro Ile Glu Glu Thr Gly Ala 305 310 315 320 Lys Leu Arg Asp Leu Met Ser Trp Val Lys Val Asp Ala Arg Ala Glu 325 330 335 Thr Ala <210> 287 <211> 556 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(556) <223> FRXA01145 <400> 287 taatgtagtt gtctgcccaa gcgagttaaa ctcccacgat ttacagtggg gggcagacat 60 cttttcacca aaatttttac gaaaggcgag attttctccc atg gct att gaa ctg 115 Met Ala Ile Glu Leu 1 5 ctt tat gat gct gac gct gac ctc tcc ttg atc cag ggc cgt aag gtt 163 Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile Gln Gly Arg Lys Val 10 15 20 gcc atc gtt ggc tac ggc tcc cag ggc cac gca cac tcc cag aac ctc 211 Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala His Ser Gln Asn Leu 25 30 35 cgc gat tct ggc gtt gag gtt gtc att ggt ctg cgc gag ggc tcc aag 259 Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu Arg Glu Gly Ser Lys 40 45 50 tcc gca gag aag gca aag gaa gca ggc ttc gag gtc aag acc acc gct 307 Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu Val Lys Thr Thr Ala 55 60 65 gag gct gca gct tgg gct gac gtc atc atg ctc ctg gct cca gac acc 355 Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu Leu Ala Pro Asp Thr 70 75 80 85 tcc cag gca gaa atc ttc acc aac gac atc gag cca aac ctg aac gca 403 Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu Pro Asn Leu Asn Ala 90 95 100 ggc gac gca ctg ctg ttc ggc cac ggc ctg aac att cac ttc gac ctg 451 Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn Ile His Phe Asp Leu 105 110 115 atc aag cca gct gac gac atc atc gtt ggc atg gtt gcg cca aag ggc 499 Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met Val Ala Pro Lys Gly 120 125 130 cca ggc cac ttg gtt cgc cgt cag ttc gtt gat ggc aag ggt gtt cct 547 Pro Gly His Leu Val Arg Arg Gln Phe Val Asp Gly Lys Gly Val Pro 135 140 145 tgc ctc atc 556 Cys Leu Ile 150 <210> 288 <211> 152 <212> PRT <213> Corynebacterium glutamicum <400> 288 Met Ala Ile Glu Leu Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile 1 5 10 15 Gln Gly Arg Lys Val Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala 20 25 30 His Ser Gln Asn Leu Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu 35 40 45 Arg Glu Gly Ser Lys Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu 50 55 60 Val Lys Thr Thr Ala Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu 65 70 75 80 Leu Ala Pro Asp Thr Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu 85 90 95 Pro Asn Leu Asn Ala Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn 100 105 110 Ile His Phe Asp Leu Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met 115 120 125 Val Ala Pro Lys Gly Pro Gly His Leu Val Arg Arg Gln Phe Val Asp 130 135 140 Gly Lys Gly Val Pro Cys Leu Ile 145 150 <210> 289 <211> 1350 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1327) <223> RXA02375 <400> 289 cttttcaggt ctacgtgtat acgatggtaa cgctatgaat gatacgcaga acacacctga 60 aagcgttcga ttacgggata atctcccaac gccaacccaa atg gcg ccg gtg aca 115 Met Ala Pro Val Thr 1 5 ggg ctt cct gtc acc ccc tac agc cag gaa gca agc atc ggt gcg agc 163 Gly Leu Pro Val Thr Pro Tyr Ser Gln Glu Ala Ser Ile Gly Ala Ser 10 15 20 ttc ccg gca gtg gat ccg gac acc aaa gac agc gcc gca tac gga cat 211 Phe Pro Ala Val Asp Pro Asp Thr Lys Asp Ser Ala Ala Tyr Gly His 25 30 35 gaa tcc gga atg cgt gag cgc atc tcc aac gct aag cga gtg gtg gtg 259 Glu Ser Gly Met Arg Glu Arg Ile Ser Asn Ala Lys Arg Val Val Val 40 45 50 aaa att ggt tcg tcc tca ttg act aac gat gag gac gga cac acc gtc 307 Lys Ile Gly Ser Ser Ser Leu Thr Asn Asp Glu Asp Gly His Thr Val 55 60 65 gat ccc aac cgc atc aac act att gtc aat gcc ttg caa gca cgc atg 355 Asp Pro Asn Arg Ile Asn Thr Ile Val Asn Ala Leu Gln Ala Arg Met 70 75 80 85 gaa gct ggc tcg gac ctc atc gtt gtg tcc tct ggc gca gtg gcc gcg 403 Glu Ala Gly Ser Asp Leu Ile Val Val Ser Ser Gly Ala Val Ala Ala 90 95 100 gga atg gcc ccg ctt gga ttg agc acc cgg ccc acg gaa ttg gca gtc 451 Gly Met Ala Pro Leu Gly Leu Ser Thr Arg Pro Thr Glu Leu Ala Val 105 110 115 aag cag gct gca gca gca gtg ggg caa gtt cac ctc atg cac cag tgg 499 Lys Gln Ala Ala Ala Ala Val Gly Gln Val His Leu Met His Gln Trp 120 125 130 gga cgt tct ttt gcc cgg tat ggt cgc ccc atc ggc cag gtg ctt ctt 547 Gly Arg Ser Phe Ala Arg Tyr Gly Arg Pro Ile Gly Gln Val Leu Leu 135 140 145 acc gca gct gat gca gga aag cgt gat cgt gcg agg aat gcg cag cgt 595 Thr Ala Ala Asp Ala Gly Lys Arg Asp Arg Ala Arg Asn Ala Gln Arg 150 155 160 165 acc atc gac aag ctg cgc att ttg ggc gcg gtt cct atc gtc aat gaa 643 Thr Ile Asp Lys Leu Arg Ile Leu Gly Ala Val Pro Ile Val Asn Glu 170 175 180 aat gac acc gtg gca acc acc ggt gtg aat ttt ggt gac aac gac cga 691 Asn Asp Thr Val Ala Thr Thr Gly Val Asn Phe Gly Asp Asn Asp Arg 185 190 195 ctt gct gca att gtg gcg cac ctg gtg tcg gct gat gct ttg gtg ctg 739 Leu Ala Ala Ile Val Ala His Leu Val Ser Ala Asp Ala Leu Val Leu 200 205 210 ctc agt gac gtg gat gga ctt ttt gat aaa aac cct act gat ccc acc 787 Leu Ser Asp Val Asp Gly Leu Phe Asp Lys Asn Pro Thr Asp Pro Thr 215 220 225 gcg aag ttt att tcc gag gtt cgt gac ggc aat gat ttg aaa ggt gtc 835 Ala Lys Phe Ile Ser Glu Val Arg Asp Gly Asn Asp Leu Lys Gly Val 230 235 240 245 att gcc ggc gac ggc gga aaa gtg ggc acc ggt ggc atg gca tca aag 883 Ile Ala Gly Asp Gly Gly Lys Val Gly Thr Gly Gly Met Ala Ser Lys 250 255 260 gtg tct gct gca cgt ttg gct tcc cga agt ggc gtg cct gtg ctg ttg 931 Val Ser Ala Ala Arg Leu Ala Ser Arg Ser Gly Val Pro Val Leu Leu 265 270 275 acc tct gcg gca aac att ggc cca gca ctg gaa gac gcc cag gtg ggc 979 Thr Ser Ala Ala Asn Ile Gly Pro Ala Leu Glu Asp Ala Gln Val Gly 280 285 290 act gta ttc cac ccc aag gac aac cgc ctc tcc gcg tgg aag ttc tgg 1027 Thr Val Phe His Pro Lys Asp Asn Arg Leu Ser Ala Trp Lys Phe Trp 295 300 305 gct ttg tat gcc gca gat act gca gga aag atc cga ctc gat gac ggc 1075 Ala Leu Tyr Ala Ala Asp Thr Ala Gly Lys Ile Arg Leu Asp Asp Gly 310 315 320 325 gcg gtg gaa gca gtg acc tcc ggt ggt aaa tct ttg ctg gct gtg ggc 1123 Ala Val Glu Ala Val Thr Ser Gly Gly Lys Ser Leu Leu Ala Val Gly 330 335 340 att act gaa atc att ggt gat ttc cag cag ggt gag atc gtg gag atc 1171 Ile Thr Glu Ile Ile Gly Asp Phe Gln Gln Gly Glu Ile Val Glu Ile 345 350 355 ttg gga cct gcc ggc caa atc atc ggg cga ggc gag gtg tcc tac gat 1219 Leu Gly Pro Ala Gly Gln Ile Ile Gly Arg Gly Glu Val Ser Tyr Asp 360 365 370 tct gat acc ttg caa tca atg gtt ggt atg caa acg cag gac ctt cca 1267 Ser Asp Thr Leu Gln Ser Met Val Gly Met Gln Thr Gln Asp Leu Pro 375 380 385 gat ggc atg cag cgc ccg gta gtg cat gca gat tat ctg tcc aac tac 1315 Asp Gly Met Gln Arg Pro Val Val His Ala Asp Tyr Leu Ser Asn Tyr 390 395 400 405 gcc agc cgc gcg taaagcgcgg gcctgctggt ggc 1350 Ala Ser Arg Ala <210> 290 <211> 409 <212> PRT <213> Corynebacterium glutamicum <400> 290 Met Ala Pro Val Thr Gly Leu Pro Val Thr Pro Tyr Ser Gln Glu Ala 1 5 10 15 Ser Ile Gly Ala Ser Phe Pro Ala Val Asp Pro Asp Thr Lys Asp Ser 20 25 30 Ala Ala Tyr Gly His Glu Ser Gly Met Arg Glu Arg Ile Ser Asn Ala 35 40 45 Lys Arg Val Val Val Lys Ile Gly Ser Ser Ser Leu Thr Asn Asp Glu 50 55 60 Asp Gly His Thr Val Asp Pro Asn Arg Ile Asn Thr Ile Val Asn Ala 65 70 75 80 Leu Gln Ala Arg Met Glu Ala Gly Ser Asp Leu Ile Val Val Ser Ser 85 90 95 Gly Ala Val Ala Ala Gly Met Ala Pro Leu Gly Leu Ser Thr Arg Pro 100 105 110 Thr Glu Leu Ala Val Lys Gln Ala Ala Ala Ala Val Gly Gln Val His 115 120 125 Leu Met His Gln Trp Gly Arg Ser Phe Ala Arg Tyr Gly Arg Pro Ile 130 135 140 Gly Gln Val Leu Leu Thr Ala Ala Asp Ala Gly Lys Arg Asp Arg Ala 145 150 155 160 Arg Asn Ala Gln Arg Thr Ile Asp Lys Leu Arg Ile Leu Gly Ala Val 165 170 175 Pro Ile Val Asn Glu Asn Asp Thr Val Ala Thr Thr Gly Val Asn Phe 180 185 190 Gly Asp Asn Asp Arg Leu Ala Ala Ile Val Ala His Leu Val Ser Ala 195 200 205 Asp Ala Leu Val Leu Leu Ser Asp Val Asp Gly Leu Phe Asp Lys Asn 210 215 220 Pro Thr Asp Pro Thr Ala Lys Phe Ile Ser Glu Val Arg Asp Gly Asn 225 230 235 240 Asp Leu Lys Gly Val Ile Ala Gly Asp Gly Gly Lys Val Gly Thr Gly 245 250 255 Gly Met Ala Ser Lys Val Ser Ala Ala Arg Leu Ala Ser Arg Ser Gly 260 265 270 Val Pro Val Leu Leu Thr Ser Ala Ala Asn Ile Gly Pro Ala Leu Glu 275 280 285 Asp Ala Gln Val Gly Thr Val Phe His Pro Lys Asp Asn Arg Leu Ser 290 295 300 Ala Trp Lys Phe Trp Ala Leu Tyr Ala Ala Asp Thr Ala Gly Lys Ile 305 310 315 320 Arg Leu Asp Asp Gly Ala Val Glu Ala Val Thr Ser Gly Gly Lys Ser 325 330 335 Leu Leu Ala Val Gly Ile Thr Glu Ile Ile Gly Asp Phe Gln Gln Gly 340 345 350 Glu Ile Val Glu Ile Leu Gly Pro Ala Gly Gln Ile Ile Gly Arg Gly 355 360 365 Glu Val Ser Tyr Asp Ser Asp Thr Leu Gln Ser Met Val Gly Met Gln 370 375 380 Thr Gln Asp Leu Pro Asp Gly Met Gln Arg Pro Val Val His Ala Asp 385 390 395 400 Tyr Leu Ser Asn Tyr Ala Ser Arg Ala 405 <210> 291 <211> 1419 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1396) <223> RXN02382 <400> 291 gagcagatgg ccaccgaggt cgatgtggtg gctggctact aggcctttta tggtgtgatc 60 cgacactgtt gcttcttaag ggtctgtata gtgggcaacc atg agt tca acg acc 115 Met Ser Ser Thr Thr 1 5 cta act gat gac caa att cgc gac aat gag cgg acc gaa gtt cta gct 163 Leu Thr Asp Asp Gln Ile Arg Asp Asn Glu Arg Thr Glu Val Leu Ala 10 15 20 aaa gca act gca gct aag aac atc gtc ccg gat att gca gtg ttg ggc 211 Lys Ala Thr Ala Ala Lys Asn Ile Val Pro Asp Ile Ala Val Leu Gly 25 30 35 acc gga ccg aag aac gca atc ctg cgt gcg gcg gca gat gaa ctc gtt 259 Thr Gly Pro Lys Asn Ala Ile Leu Arg Ala Ala Ala Asp Glu Leu Val 40 45 50 gca cgc agc gca gaa atc atc gaa gcc aac gct tcc gat atc gaa gcg 307 Ala Arg Ser Ala Glu Ile Ile Glu Ala Asn Ala Ser Asp Ile Glu Ala 55 60 65 ggt cgc gca aac ggc atg gaa gaa tcc atg att gat cgc ctt gcc ctt 355 Gly Arg Ala Asn Gly Met Glu Glu Ser Met Ile Asp Arg Leu Ala Leu 70 75 80 85 gat gaa tct cgc att gag ggc atc gct ggc ggt ttg cgc cag gtt gct 403 Asp Glu Ser Arg Ile Glu Gly Ile Ala Gly Gly Leu Arg Gln Val Ala 90 95 100 ggc ctg acc gac cca gtg ggt gaa gta ctg cgc gga cat gtc atg gaa 451 Gly Leu Thr Asp Pro Val Gly Glu Val Leu Arg Gly His Val Met Glu 105 110 115 aac ggc att cag atg aag cag gtc cgt gtg cct ttg ggc gtg atg ggc 499 Asn Gly Ile Gln Met Lys Gln Val Arg Val Pro Leu Gly Val Met Gly 120 125 130 atg gtc tat gaa gcc cgc cct aac gtc acc gtc gac gcc ttc ggc ctg 547 Met Val Tyr Glu Ala Arg Pro Asn Val Thr Val Asp Ala Phe Gly Leu 135 140 145 gca ctc aag tcc gga aac gta gct ttg ctg cgc ggt tcc tcc aca gct 595 Ala Leu Lys Ser Gly Asn Val Ala Leu Leu Arg Gly Ser Ser Thr Ala 150 155 160 165 gtg cat tcc aac acc aag ctc gtg gaa atc ctg cag gac gtc ctc gag 643 Val His Ser Asn Thr Lys Leu Val Glu Ile Leu Gln Asp Val Leu Glu 170 175 180 cgt ttc gag ctg cca cgc gaa acc gtg cag ttg ctg cct tgc caa acc 691 Arg Phe Glu Leu Pro Arg Glu Thr Val Gln Leu Leu Pro Cys Gln Thr 185 190 195 cgc gga tcc gtc caa gat ttg atc acc gca cgc ggc ctc gtt gac gtg 739 Arg Gly Ser Val Gln Asp Leu Ile Thr Ala Arg Gly Leu Val Asp Val 200 205 210 gtc atc cca cgc ggc ggc gca gga cta atc aac gca gtg gtc acc ggt 787 Val Ile Pro Arg Gly Gly Ala Gly Leu Ile Asn Ala Val Val Thr Gly 215 220 225 gcg acc gtg ccc acc att gaa acc ggc acc ggc aac tgc cac ttc tac 835 Ala Thr Val Pro Thr Ile Glu Thr Gly Thr Gly Asn Cys His Phe Tyr 230 235 240 245 atc gat gcc gaa gcc aag ctt gat cag gca atc gcc atg gtc atc aac 883 Ile Asp Ala Glu Ala Lys Leu Asp Gln Ala Ile Ala Met Val Ile Asn 250 255 260 ggc aag acc cgc cgc tgc agc gtg tgc aac gct act gaa acc gcg ctt 931 Gly Lys Thr Arg Arg Cys Ser Val Cys Asn Ala Thr Glu Thr Ala Leu 265 270 275 ctc gac gcc gcc ctc agc gac tca gac aag ctt gca gtc gtc cag gcg 979 Leu Asp Ala Ala Leu Ser Asp Ser Asp Lys Leu Ala Val Val Gln Ala 280 285 290 ctc cag gaa gca gga gtc aca att cat gga cgg gtg gcc gaa ttg gaa 1027 Leu Gln Glu Ala Gly Val Thr Ile His Gly Arg Val Ala Glu Leu Glu 295 300 305 gca ttc ggt gca acc gac gtg gtg gaa gca act gaa act gac tgg gat 1075 Ala Phe Gly Ala Thr Asp Val Val Glu Ala Thr Glu Thr Asp Trp Asp 310 315 320 325 tct gag tac ctg tcc ttc gat atc gct gtc gct gtg gtt gac ggt gtg 1123 Ser Glu Tyr Leu Ser Phe Asp Ile Ala Val Ala Val Val Asp Gly Val 330 335 340 gat gga gct ctg gca cac atc gct aag tac agc acc aag cac acc gaa 1171 Asp Gly Ala Leu Ala His Ile Ala Lys Tyr Ser Thr Lys His Thr Glu 345 350 355 gcg atc gcc acc caa aac att gaa acc gct cag cgc ttt gca gat cgc 1219 Ala Ile Ala Thr Gln Asn Ile Glu Thr Ala Gln Arg Phe Ala Asp Arg 360 365 370 gtc gat gca gca gcg gtg atg ata aac gca tcc acc gcc tac acc gat 1267 Val Asp Ala Ala Ala Val Met Ile Asn Ala Ser Thr Ala Tyr Thr Asp 375 380 385 ggg gag cag tac ggc atg ggc gcg gag atc ggc att tcc acc cag aaa 1315 Gly Glu Gln Tyr Gly Met Gly Ala Glu Ile Gly Ile Ser Thr Gln Lys 390 395 400 405 ctg cat gca cgt gga cca atg gcc ctg cca gag ctg acc tcc acc aag 1363 Leu His Ala Arg Gly Pro Met Ala Leu Pro Glu Leu Thr Ser Thr Lys 410 415 420 tgg att ctg cag ggc aca gga caa att agg cct taagtttgaa gaagtaatca 1416 Trp Ile Leu Gln Gly Thr Gly Gln Ile Arg Pro 425 430 agc 1419 <210> 292 <211> 432 <212> PRT <213> Corynebacterium glutamicum <400> 292 Met Ser Ser Thr Thr Leu Thr Asp Asp Gln Ile Arg Asp Asn Glu Arg 1 5 10 15 Thr Glu Val Leu Ala Lys Ala Thr Ala Ala Lys Asn Ile Val Pro Asp 20 25 30 Ile Ala Val Leu Gly Thr Gly Pro Lys Asn Ala Ile Leu Arg Ala Ala 35 40 45 Ala Asp Glu Leu Val Ala Arg Ser Ala Glu Ile Ile Glu Ala Asn Ala 50 55 60 Ser Asp Ile Glu Ala Gly Arg Ala Asn Gly Met Glu Glu Ser Met Ile 65 70 75 80 Asp Arg Leu Ala Leu Asp Glu Ser Arg Ile Glu Gly Ile Ala Gly Gly 85 90 95 Leu Arg Gln Val Ala Gly Leu Thr Asp Pro Val Gly Glu Val Leu Arg 100 105 110 Gly His Val Met Glu Asn Gly Ile Gln Met Lys Gln Val Arg Val Pro 115 120 125 Leu Gly Val Met Gly Met Val Tyr Glu Ala Arg Pro Asn Val Thr Val 130 135 140 Asp Ala Phe Gly Leu Ala Leu Lys Ser Gly Asn Val Ala Leu Leu Arg 145 150 155 160 Gly Ser Ser Thr Ala Val His Ser Asn Thr Lys Leu Val Glu Ile Leu 165 170 175 Gln Asp Val Leu Glu Arg Phe Glu Leu Pro Arg Glu Thr Val Gln Leu 180 185 190 Leu Pro Cys Gln Thr Arg Gly Ser Val Gln Asp Leu Ile Thr Ala Arg 195 200 205 Gly Leu Val Asp Val Val Ile Pro Arg Gly Gly Ala Gly Leu Ile Asn 210 215 220 Ala Val Val Thr Gly Ala Thr Val Pro Thr Ile Glu Thr Gly Thr Gly 225 230 235 240 Asn Cys His Phe Tyr Ile Asp Ala Glu Ala Lys Leu Asp Gln Ala Ile 245 250 255 Ala Met Val Ile Asn Gly Lys Thr Arg Arg Cys Ser Val Cys Asn Ala 260 265 270 Thr Glu Thr Ala Leu Leu Asp Ala Ala Leu Ser Asp Ser Asp Lys Leu 275 280 285 Ala Val Val Gln Ala Leu Gln Glu Ala Gly Val Thr Ile His Gly Arg 290 295 300 Val Ala Glu Leu Glu Ala Phe Gly Ala Thr Asp Val Val Glu Ala Thr 305 310 315 320 Glu Thr Asp Trp Asp Ser Glu Tyr Leu Ser Phe Asp Ile Ala Val Ala 325 330 335 Val Val Asp Gly Val Asp Gly Ala Leu Ala His Ile Ala Lys Tyr Ser 340 345 350 Thr Lys His Thr Glu Ala Ile Ala Thr Gln Asn Ile Glu Thr Ala Gln 355 360 365 Arg Phe Ala Asp Arg Val Asp Ala Ala Ala Val Met Ile Asn Ala Ser 370 375 380 Thr Ala Tyr Thr Asp Gly Glu Gln Tyr Gly Met Gly Ala Glu Ile Gly 385 390 395 400 Ile Ser Thr Gln Lys Leu His Ala Arg Gly Pro Met Ala Leu Pro Glu 405 410 415 Leu Thr Ser Thr Lys Trp Ile Leu Gln Gly Thr Gly Gln Ile Arg Pro 420 425 430 <210> 293 <211> 724 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(709) <223> FRXA02378 <400> 293 gagcagatgg ccaccgaggt cgatgtggtg gctggctact aggcctttta tggtgtgatc 60 cgacactgtt gcttcttaag ggtctgtata gtgggcaacc atg agt tca acg acc 115 Met Ser Ser Thr Thr 1 5 cta act gat gac caa att cgc gac aat gag cgg acc gaa gtt cta gct 163 Leu Thr Asp Asp Gln Ile Arg Asp Asn Glu Arg Thr Glu Val Leu Ala 10 15 20 aaa gca act gca gct aag aac atc gtc ccg gat att gca gtg ttg ggc 211 Lys Ala Thr Ala Ala Lys Asn Ile Val Pro Asp Ile Ala Val Leu Gly 25 30 35 acc gga ccg aag aac gca atc ctg cgt gcg gcg gca gat gaa ctc gtt 259 Thr Gly Pro Lys Asn Ala Ile Leu Arg Ala Ala Ala Asp Glu Leu Val 40 45 50 gca cgc agc gca gaa atc atc gaa gcc aac gct tcc gat atc gaa gcg 307 Ala Arg Ser Ala Glu Ile Ile Glu Ala Asn Ala Ser Asp Ile Glu Ala 55 60 65 ggt cgc gca aac ggc atg gaa gaa tcc atg att gat cgc ctt gcc ctt 355 Gly Arg Ala Asn Gly Met Glu Glu Ser Met Ile Asp Arg Leu Ala Leu 70 75 80 85 gat gaa tct cgc att gag ggc atc gct ggc ggt ttg cgc cag gtt gct 403 Asp Glu Ser Arg Ile Glu Gly Ile Ala Gly Gly Leu Arg Gln Val Ala 90 95 100 ggc ctg acc gac cca gtg ggt gaa gta ctg cgc gga cat gtc atg gaa 451 Gly Leu Thr Asp Pro Val Gly Glu Val Leu Arg Gly His Val Met Glu 105 110 115 aac ggc att cag atg aag cag gtc cgt gtg cct ttg ggc gtg atg ggc 499 Asn Gly Ile Gln Met Lys Gln Val Arg Val Pro Leu Gly Val Met Gly 120 125 130 atg gtc tat gaa gcc cgc cct aac gtc acc gtc gac gcc ttc ggc ctg 547 Met Val Tyr Glu Ala Arg Pro Asn Val Thr Val Asp Ala Phe Gly Leu 135 140 145 gca ctc aag tcc gga aac gta gct ttg ctg cgc ggt tcc tcc aca gct 595 Ala Leu Lys Ser Gly Asn Val Ala Leu Leu Arg Gly Ser Ser Thr Ala 150 155 160 165 gtg cat tcc aac acc aag ctc gtg gaa atc ctg cag gac gta ctc gag 643 Val His Ser Asn Thr Lys Leu Val Glu Ile Leu Gln Asp Val Leu Glu 170 175 180 cgt ttc gag ctg cca cgc gaa acc gtg cag ttg ctg ctt gcc aaa ccc 691 Arg Phe Glu Leu Pro Arg Glu Thr Val Gln Leu Leu Leu Ala Lys Pro 185 190 195 gcg gat ccg tcc aag att tgatcaccgg acgcg 724 Ala Asp Pro Ser Lys Ile 200 <210> 294 <211> 203 <212> PRT <213> Corynebacterium glutamicum <400> 294 Met Ser Ser Thr Thr Leu Thr Asp Asp Gln Ile Arg Asp Asn Glu Arg 1 5 10 15 Thr Glu Val Leu Ala Lys Ala Thr Ala Ala Lys Asn Ile Val Pro Asp 20 25 30 Ile Ala Val Leu Gly Thr Gly Pro Lys Asn Ala Ile Leu Arg Ala Ala 35 40 45 Ala Asp Glu Leu Val Ala Arg Ser Ala Glu Ile Ile Glu Ala Asn Ala 50 55 60 Ser Asp Ile Glu Ala Gly Arg Ala Asn Gly Met Glu Glu Ser Met Ile 65 70 75 80 Asp Arg Leu Ala Leu Asp Glu Ser Arg Ile Glu Gly Ile Ala Gly Gly 85 90 95 Leu Arg Gln Val Ala Gly Leu Thr Asp Pro Val Gly Glu Val Leu Arg 100 105 110 Gly His Val Met Glu Asn Gly Ile Gln Met Lys Gln Val Arg Val Pro 115 120 125 Leu Gly Val Met Gly Met Val Tyr Glu Ala Arg Pro Asn Val Thr Val 130 135 140 Asp Ala Phe Gly Leu Ala Leu Lys Ser Gly Asn Val Ala Leu Leu Arg 145 150 155 160 Gly Ser Ser Thr Ala Val His Ser Asn Thr Lys Leu Val Glu Ile Leu 165 170 175 Gln Asp Val Leu Glu Arg Phe Glu Leu Pro Arg Glu Thr Val Gln Leu 180 185 190 Leu Leu Ala Lys Pro Ala Asp Pro Ser Lys Ile 195 200 <210> 295 <211> 623 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(600) <223> FRXA02382 <400> 295 ccc acc att gaa acc ggc acc ggc aac tgc cac ttc tac atc gat gcc 48 Pro Thr Ile Glu Thr Gly Thr Gly Asn Cys His Phe Tyr Ile Asp Ala 1 5 10 15 gaa gcc aag ctt gat cag gca atc gcc atg gtc atc aac ggc aag acc 96 Glu Ala Lys Leu Asp Gln Ala Ile Ala Met Val Ile Asn Gly Lys Thr 20 25 30 cgc cgc tgc agc gtg tgc aac gct act gaa acc gcg ctt ctc gac gcc 144 Arg Arg Cys Ser Val Cys Asn Ala Thr Glu Thr Ala Leu Leu Asp Ala 35 40 45 gcc ctc agc gac tca gac aag ctt gca gtc gtc cag gcg ctc cag gaa 192 Ala Leu Ser Asp Ser Asp Lys Leu Ala Val Val Gln Ala Leu Gln Glu 50 55 60 gca gga gtc aca att cat gga cgg gtg gcc gaa ttg gaa gca ttc ggt 240 Ala Gly Val Thr Ile His Gly Arg Val Ala Glu Leu Glu Ala Phe Gly 65 70 75 80 gca acc gac gtg gtg gaa gca act gaa act gac tgg gat tct gag tac 288 Ala Thr Asp Val Val Glu Ala Thr Glu Thr Asp Trp Asp Ser Glu Tyr 85 90 95 ctg tcc ttc gat atc gct gtc gct gtg gtt gac ggt gtg gat gga gct 336 Leu Ser Phe Asp Ile Ala Val Ala Val Val Asp Gly Val Asp Gly Ala 100 105 110 ctg gca cac atc gct aag tac agc acc aag cac acc gaa gcg atc gcc 384 Leu Ala His Ile Ala Lys Tyr Ser Thr Lys His Thr Glu Ala Ile Ala 115 120 125 acc caa aac att gaa acc gct cag cgc ttt gca gat cgc gtc gat gca 432 Thr Gln Asn Ile Glu Thr Ala Gln Arg Phe Ala Asp Arg Val Asp Ala 130 135 140 gca gcg gtg atg ata aac gca tcc acc gcc tac acc gat ggg gag cag 480 Ala Ala Val Met Ile Asn Ala Ser Thr Ala Tyr Thr Asp Gly Glu Gln 145 150 155 160 tac ggc atg ggc gcg gag atc ggc att tcc acc cag aaa ctg cat gca 528 Tyr Gly Met Gly Ala Glu Ile Gly Ile Ser Thr Gln Lys Leu His Ala 165 170 175 cgt gga cca atg gcc ctg cca gag ctg acc tcc acc aag tgg att ctg 576 Arg Gly Pro Met Ala Leu Pro Glu Leu Thr Ser Thr Lys Trp Ile Leu 180 185 190 cag ggc aca gga caa att agg cct taagtttgaa gaagtaatca agc 623 Gln Gly Thr Gly Gln Ile Arg Pro 195 200 <210> 296 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 296 Pro Thr Ile Glu Thr Gly Thr Gly Asn Cys His Phe Tyr Ile Asp Ala 1 5 10 15 Glu Ala Lys Leu Asp Gln Ala Ile Ala Met Val Ile Asn Gly Lys Thr 20 25 30 Arg Arg Cys Ser Val Cys Asn Ala Thr Glu Thr Ala Leu Leu Asp Ala 35 40 45 Ala Leu Ser Asp Ser Asp Lys Leu Ala Val Val Gln Ala Leu Gln Glu 50 55 60 Ala Gly Val Thr Ile His Gly Arg Val Ala Glu Leu Glu Ala Phe Gly 65 70 75 80 Ala Thr Asp Val Val Glu Ala Thr Glu Thr Asp Trp Asp Ser Glu Tyr 85 90 95 Leu Ser Phe Asp Ile Ala Val Ala Val Val Asp Gly Val Asp Gly Ala 100 105 110 Leu Ala His Ile Ala Lys Tyr Ser Thr Lys His Thr Glu Ala Ile Ala 115 120 125 Thr Gln Asn Ile Glu Thr Ala Gln Arg Phe Ala Asp Arg Val Asp Ala 130 135 140 Ala Ala Val Met Ile Asn Ala Ser Thr Ala Tyr Thr Asp Gly Glu Gln 145 150 155 160 Tyr Gly Met Gly Ala Glu Ile Gly Ile Ser Thr Gln Lys Leu His Ala 165 170 175 Arg Gly Pro Met Ala Leu Pro Glu Leu Thr Ser Thr Lys Trp Ile Leu 180 185 190 Gln Gly Thr Gly Gln Ile Arg Pro 195 200 <210> 297 <211> 933 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(910) <223> RXA02499 <400> 297 cctggtcatg acgttcgggc cgctggcaat cgtcatgtaa tttgtcgttt tgggcccccg 60 ctgctgcaaa acaggggtgg ttagtggcag tgtgggaacc atg aca aca att gct 115 Met Thr Thr Ile Ala 1 5 gta atc ggc ggc gga caa atc ggc gag gct tta gtc tca ggt ttg atc 163 Val Ile Gly Gly Gly Gln Ile Gly Glu Ala Leu Val Ser Gly Leu Ile 10 15 20 gcg gcc aac atg aat cca caa aat att cgc gtc acc aac cgt tcg gaa 211 Ala Ala Asn Met Asn Pro Gln Asn Ile Arg Val Thr Asn Arg Ser Glu 25 30 35 gag cgc ggc caa gag ctg cgt gac cgc tac ggc atc ctc aac atg acg 259 Glu Arg Gly Gln Glu Leu Arg Asp Arg Tyr Gly Ile Leu Asn Met Thr 40 45 50 gat aat tcc caa gcc gca gac gaa gcc gac gtg gtg ttc ctg tgc gtg 307 Asp Asn Ser Gln Ala Ala Asp Glu Ala Asp Val Val Phe Leu Cys Val 55 60 65 aag ccg aaa ttt atc gtc gaa gtg ctc tcc gaa atc acc ggc act ttg 355 Lys Pro Lys Phe Ile Val Glu Val Leu Ser Glu Ile Thr Gly Thr Leu 70 75 80 85 gat aac aac tcc gca caa agt gtt gtg gtc agc atg gcc gca ggc atc 403 Asp Asn Asn Ser Ala Gln Ser Val Val Val Ser Met Ala Ala Gly Ile 90 95 100 agc atc gct gcc atg gaa gaa agc gcc tct gcg ggg ctc ccc gtc gtg 451 Ser Ile Ala Ala Met Glu Glu Ser Ala Ser Ala Gly Leu Pro Val Val 105 110 115 cgc gtc atg ccg aac act cca atg ctc gtg ggc aag ggc atg tcg act 499 Arg Val Met Pro Asn Thr Pro Met Leu Val Gly Lys Gly Met Ser Thr 120 125 130 gtc acc aaa ggc cgc tac gtt gac gcg gaa cag ttg gaa caa gtc aag 547 Val Thr Lys Gly Arg Tyr Val Asp Ala Glu Gln Leu Glu Gln Val Lys 135 140 145 gac ttg ttg agc acc gtt gga gac gtc ctc gaa gtc gcg gaa tca gac 595 Asp Leu Leu Ser Thr Val Gly Asp Val Leu Glu Val Ala Glu Ser Asp 150 155 160 165 atc gac gca gtc acc gcg atg tcc gga tcc tcc cct gca tac ctg ttc 643 Ile Asp Ala Val Thr Ala Met Ser Gly Ser Ser Pro Ala Tyr Leu Phe 170 175 180 ctt gtg acc gaa gcg ctc att gag gca gga gtt aat cta ggc ctg ccc 691 Leu Val Thr Glu Ala Leu Ile Glu Ala Gly Val Asn Leu Gly Leu Pro 185 190 195 cgc gcg acc gct aaa aag ctc gct gtg gcc tca ttc gaa ggt gct gca 739 Arg Ala Thr Ala Lys Lys Leu Ala Val Ala Ser Phe Glu Gly Ala Ala 200 205 210 acc atg atg aag gaa acc ggc aaa gaa ccc tca gaa ttg cgc gca ggc 787 Thr Met Met Lys Glu Thr Gly Lys Glu Pro Ser Glu Leu Arg Ala Gly 215 220 225 gtt tcc tca ccc gca ggc acc acc gtc gca gcc atc cga gaa ctc gaa 835 Val Ser Ser Pro Ala Gly Thr Thr Val Ala Ala Ile Arg Glu Leu Glu 230 235 240 245 gaa agc gga atc cga ggc gct ttc tac cgc gca gcc caa gct tgc gcc 883 Glu Ser Gly Ile Arg Gly Ala Phe Tyr Arg Ala Ala Gln Ala Cys Ala 250 255 260 gac cga tct gaa gaa ctc gga aag cgc tagaaaccgt tatttccccg 930 Asp Arg Ser Glu Glu Leu Gly Lys Arg 265 270 tta 933 <210> 298 <211> 270 <212> PRT <213> Corynebacterium glutamicum <400> 298 Met Thr Thr Ile Ala Val Ile Gly Gly Gly Gln Ile Gly Glu Ala Leu 1 5 10 15 Val Ser Gly Leu Ile Ala Ala Asn Met Asn Pro Gln Asn Ile Arg Val 20 25 30 Thr Asn Arg Ser Glu Glu Arg Gly Gln Glu Leu Arg Asp Arg Tyr Gly 35 40 45 Ile Leu Asn Met Thr Asp Asn Ser Gln Ala Ala Asp Glu Ala Asp Val 50 55 60 Val Phe Leu Cys Val Lys Pro Lys Phe Ile Val Glu Val Leu Ser Glu 65 70 75 80 Ile Thr Gly Thr Leu Asp Asn Asn Ser Ala Gln Ser Val Val Val Ser 85 90 95 Met Ala Ala Gly Ile Ser Ile Ala Ala Met Glu Glu Ser Ala Ser Ala 100 105 110 Gly Leu Pro Val Val Arg Val Met Pro Asn Thr Pro Met Leu Val Gly 115 120 125 Lys Gly Met Ser Thr Val Thr Lys Gly Arg Tyr Val Asp Ala Glu Gln 130 135 140 Leu Glu Gln Val Lys Asp Leu Leu Ser Thr Val Gly Asp Val Leu Glu 145 150 155 160 Val Ala Glu Ser Asp Ile Asp Ala Val Thr Ala Met Ser Gly Ser Ser 165 170 175 Pro Ala Tyr Leu Phe Leu Val Thr Glu Ala Leu Ile Glu Ala Gly Val 180 185 190 Asn Leu Gly Leu Pro Arg Ala Thr Ala Lys Lys Leu Ala Val Ala Ser 195 200 205 Phe Glu Gly Ala Ala Thr Met Met Lys Glu Thr Gly Lys Glu Pro Ser 210 215 220 Glu Leu Arg Ala Gly Val Ser Ser Pro Ala Gly Thr Thr Val Ala Ala 225 230 235 240 Ile Arg Glu Leu Glu Glu Ser Gly Ile Arg Gly Ala Phe Tyr Arg Ala 245 250 255 Ala Gln Ala Cys Ala Asp Arg Ser Glu Glu Leu Gly Lys Arg 260 265 270 <210> 299 <211> 1296 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1273) <223> RXS02157 <400> 299 gggtggaatt ggcacgatgg tgctgccgga tgtttttgat cgggagaatt atcctgaagg 60 caccgttttt agaaaagacg acaaggatgg ggaactgtaa atg agc acg ctg gaa 115 Met Ser Thr Leu Glu 1 5 act tgg cca cag gtc att att aat acg tac ggc acc cca cca gtt gag 163 Thr Trp Pro Gln Val Ile Ile Asn Thr Tyr Gly Thr Pro Pro Val Glu 10 15 20 ctg gtg tcc ggc aag ggc gca acc gtc act gat gac cag ggc aat gtc 211 Leu Val Ser Gly Lys Gly Ala Thr Val Thr Asp Asp Gln Gly Asn Val 25 30 35 tac atc gac ttg ctc gcg ggc atc gca gtc aac gcg ttg ggc cac gcc 259 Tyr Ile Asp Leu Leu Ala Gly Ile Ala Val Asn Ala Leu Gly His Ala 40 45 50 cac ccg gcg atc atc gag gcg gtc acc aac cag atc ggc caa ctt ggt 307 His Pro Ala Ile Ile Glu Ala Val Thr Asn Gln Ile Gly Gln Leu Gly 55 60 65 cac gtc tca aac ttg ttc gca tcc agg ccc gtc gtc gag gtc gcc gag 355 His Val Ser Asn Leu Phe Ala Ser Arg Pro Val Val Glu Val Ala Glu 70 75 80 85 gag ctc atc aag cgt ttt tcg ctt gac gac gcc acc ctc gcc gcg caa 403 Glu Leu Ile Lys Arg Phe Ser Leu Asp Asp Ala Thr Leu Ala Ala Gln 90 95 100 acc cgg gtt ttc ttc tgc aac tcg ggc gcc gaa gca aac gag gct gct 451 Thr Arg Val Phe Phe Cys Asn Ser Gly Ala Glu Ala Asn Glu Ala Ala 105 110 115 ttc aag att gca cgc ttg act ggt cgt tcc cgg att ctg gct gca gtt 499 Phe Lys Ile Ala Arg Leu Thr Gly Arg Ser Arg Ile Leu Ala Ala Val 120 125 130 cat ggt ttc cac ggc cgc acc atg ggt tcc ctc gcg ctg act ggc cag 547 His Gly Phe His Gly Arg Thr Met Gly Ser Leu Ala Leu Thr Gly Gln 135 140 145 cca gac aag cgt gaa gcg ttc ctg cca atg cca agc ggt gtg gag ttc 595 Pro Asp Lys Arg Glu Ala Phe Leu Pro Met Pro Ser Gly Val Glu Phe 150 155 160 165 tac cct tac ggc gac acc gat tac ttg cgc aaa atg gta gaa acc aac 643 Tyr Pro Tyr Gly Asp Thr Asp Tyr Leu Arg Lys Met Val Glu Thr Asn 170 175 180 cca acg gat gtg gct gct atc ttc ctc gag cca atc cag ggt gaa acg 691 Pro Thr Asp Val Ala Ala Ile Phe Leu Glu Pro Ile Gln Gly Glu Thr 185 190 195 ggc gtt gtt cca gca cct gaa gga ttc ctc aag gca gtg cgc gag ctg 739 Gly Val Val Pro Ala Pro Glu Gly Phe Leu Lys Ala Val Arg Glu Leu 200 205 210 tgc gat gag tac ggc atc ttg atg atc acc gat gaa gtc cag act ggc 787 Cys Asp Glu Tyr Gly Ile Leu Met Ile Thr Asp Glu Val Gln Thr Gly 215 220 225 gtt ggc cgt acc ggc gat ttc ttt gca cat cag cac gat ggc gtt gtt 835 Val Gly Arg Thr Gly Asp Phe Phe Ala His Gln His Asp Gly Val Val 230 235 240 245 ccc gat gtg gtg acc atg gcc aag gga ctt ggc ggc ggt ctt ccc atc 883 Pro Asp Val Val Thr Met Ala Lys Gly Leu Gly Gly Gly Leu Pro Ile 250 255 260 ggt gct tgt ttg gcc act ggc cgt gca gct gaa ttg atg acc cca ggc 931 Gly Ala Cys Leu Ala Thr Gly Arg Ala Ala Glu Leu Met Thr Pro Gly 265 270 275 aag cac ggc acc act ttc ggt ggc aac cca gtt gct tgt gca gct gcc 979 Lys His Gly Thr Thr Phe Gly Gly Asn Pro Val Ala Cys Ala Ala Ala 280 285 290 aag gca gtg ctg tct gtt gtc gat gac gct ttc tgc gca gaa gtt gcc 1027 Lys Ala Val Leu Ser Val Val Asp Asp Ala Phe Cys Ala Glu Val Ala 295 300 305 cgc aag ggc gag ctg ttc aag gaa ctt ctt gcc aag gtt gac ggc gtt 1075 Arg Lys Gly Glu Leu Phe Lys Glu Leu Leu Ala Lys Val Asp Gly Val 310 315 320 325 gta gac gtc cgt ggc agg ggc ttg atg ttg ggc gtg gtg ctg gag cgc 1123 Val Asp Val Arg Gly Arg Gly Leu Met Leu Gly Val Val Leu Glu Arg 330 335 340 gac gtc gca aag caa gct gtt ctt gat ggt ttt aag cac ggc gtt att 1171 Asp Val Ala Lys Gln Ala Val Leu Asp Gly Phe Lys His Gly Val Ile 345 350 355 ttg aat gca ccg gcg gac aac att atc cgt ttg acc ccg ccg ctg gtg 1219 Leu Asn Ala Pro Ala Asp Asn Ile Ile Arg Leu Thr Pro Pro Leu Val 360 365 370 atc acc gac gaa gaa atc gca gac gca gtc aag gct att gcc gag aca 1267 Ile Thr Asp Glu Glu Ile Ala Asp Ala Val Lys Ala Ile Ala Glu Thr 375 380 385 atc gca taaaggactc aaacttatga ctt 1296 Ile Ala 390 <210> 300 <211> 391 <212> PRT <213> Corynebacterium glutamicum <400> 300 Met Ser Thr Leu Glu Thr Trp Pro Gln Val Ile Ile Asn Thr Tyr Gly 1 5 10 15 Thr Pro Pro Val Glu Leu Val Ser Gly Lys Gly Ala Thr Val Thr Asp 20 25 30 Asp Gln Gly Asn Val Tyr Ile Asp Leu Leu Ala Gly Ile Ala Val Asn 35 40 45 Ala Leu Gly His Ala His Pro Ala Ile Ile Glu Ala Val Thr Asn Gln 50 55 60 Ile Gly Gln Leu Gly His Val Ser Asn Leu Phe Ala Ser Arg Pro Val 65 70 75 80 Val Glu Val Ala Glu Glu Leu Ile Lys Arg Phe Ser Leu Asp Asp Ala 85 90 95 Thr Leu Ala Ala Gln Thr Arg Val Phe Phe Cys Asn Ser Gly Ala Glu 100 105 110 Ala Asn Glu Ala Ala Phe Lys Ile Ala Arg Leu Thr Gly Arg Ser Arg 115 120 125 Ile Leu Ala Ala Val His Gly Phe His Gly Arg Thr Met Gly Ser Leu 130 135 140 Ala Leu Thr Gly Gln Pro Asp Lys Arg Glu Ala Phe Leu Pro Met Pro 145 150 155 160 Ser Gly Val Glu Phe Tyr Pro Tyr Gly Asp Thr Asp Tyr Leu Arg Lys 165 170 175 Met Val Glu Thr Asn Pro Thr Asp Val Ala Ala Ile Phe Leu Glu Pro 180 185 190 Ile Gln Gly Glu Thr Gly Val Val Pro Ala Pro Glu Gly Phe Leu Lys 195 200 205 Ala Val Arg Glu Leu Cys Asp Glu Tyr Gly Ile Leu Met Ile Thr Asp 210 215 220 Glu Val Gln Thr Gly Val Gly Arg Thr Gly Asp Phe Phe Ala His Gln 225 230 235 240 His Asp Gly Val Val Pro Asp Val Val Thr Met Ala Lys Gly Leu Gly 245 250 255 Gly Gly Leu Pro Ile Gly Ala Cys Leu Ala Thr Gly Arg Ala Ala Glu 260 265 270 Leu Met Thr Pro Gly Lys His Gly Thr Thr Phe Gly Gly Asn Pro Val 275 280 285 Ala Cys Ala Ala Ala Lys Ala Val Leu Ser Val Val Asp Asp Ala Phe 290 295 300 Cys Ala Glu Val Ala Arg Lys Gly Glu Leu Phe Lys Glu Leu Leu Ala 305 310 315 320 Lys Val Asp Gly Val Val Asp Val Arg Gly Arg Gly Leu Met Leu Gly 325 330 335 Val Val Leu Glu Arg Asp Val Ala Lys Gln Ala Val Leu Asp Gly Phe 340 345 350 Lys His Gly Val Ile Leu Asn Ala Pro Ala Asp Asn Ile Ile Arg Leu 355 360 365 Thr Pro Pro Leu Val Ile Thr Asp Glu Glu Ile Ala Asp Ala Val Lys 370 375 380 Ala Ile Ala Glu Thr Ile Ala 385 390 <210> 301 <211> 1269 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1246) <223> RXS02262 <400> 301 gcaccaattt cggacctgaa atccccgagg aaaccgtgcc cgacgccgtg caggtgggcg 60 tcgataagca aaaaatcgct gatactcgaa aggcctcaaa atg acc gca acc tac 115 Met Thr Ala Thr Tyr 1 5 acc act gaa acc gcc atc aat ttc ttg ttc ttg agc gaa ccg gac atg 163 Thr Thr Glu Thr Ala Ile Asn Phe Leu Phe Leu Ser Glu Pro Asp Met 10 15 20 atc gcg gcc gga gtc aaa gac gtc gcg caa tgc gtc gat gtc atg gag 211 Ile Ala Ala Gly Val Lys Asp Val Ala Gln Cys Val Asp Val Met Glu 25 30 35 gaa acg ctc gtg ctc ttg gcg cag ggc gac tac aaa atg gcc ggt ttg 259 Glu Thr Leu Val Leu Leu Ala Gln Gly Asp Tyr Lys Met Ala Gly Leu 40 45 50 aac tcc aac tcg cat ggc gcg atg atc acc ttc ccg gaa aac cca gaa 307 Asn Ser Asn Ser His Gly Ala Met Ile Thr Phe Pro Glu Asn Pro Glu 55 60 65 ttt gaa ggc atg ccc aag gac ggc ccc gac cgc cga ttc atg gcg atg 355 Phe Glu Gly Met Pro Lys Asp Gly Pro Asp Arg Arg Phe Met Ala Met 70 75 80 85 ccc gca tac ctc ggc ggg cga ttc aaa aac acc ggc gtg aag tgg tac 403 Pro Ala Tyr Leu Gly Gly Arg Phe Lys Asn Thr Gly Val Lys Trp Tyr 90 95 100 gga tcc aac gcg gaa aac aag gcc tca ggc ttg cct cgc tcg atc cac 451 Gly Ser Asn Ala Glu Asn Lys Ala Ser Gly Leu Pro Arg Ser Ile His 105 110 115 acc ttc gtc ctc aac gac acg gtc acc ggt gca ccg aag gcc atc atg 499 Thr Phe Val Leu Asn Asp Thr Val Thr Gly Ala Pro Lys Ala Ile Met 120 125 130 tcc gcg aac ctg ctg tcc gcc tac cgc acc ggc gcg gtt ccc ggc gtg 547 Ser Ala Asn Leu Leu Ser Ala Tyr Arg Thr Gly Ala Val Pro Gly Val 135 140 145 ggc gtg aag cac tta gcg gtc gcc gac gcg aca acc ttg gct gtc gtc 595 Gly Val Lys His Leu Ala Val Ala Asp Ala Thr Thr Leu Ala Val Val 150 155 160 165 gga cct ggt gtc atg gcg aaa acc atc acc gaa gcg tgc atc gca gag 643 Gly Pro Gly Val Met Ala Lys Thr Ile Thr Glu Ala Cys Ile Ala Glu 170 175 180 cgc cca gga atc acc acc atc aag atc aag gga cgc agc gaa cgc ggc 691 Arg Pro Gly Ile Thr Thr Ile Lys Ile Lys Gly Arg Ser Glu Arg Gly 185 190 195 atc aac gcc ttt gca aca tgg gcg ttg gaa aaa ttc ccc gag atc gaa 739 Ile Asn Ala Phe Ala Thr Trp Ala Leu Glu Lys Phe Pro Glu Ile Glu 200 205 210 gtg gtc gcc gtc gga tct gaa gaa gac gtg gtc aaa gac gcc gac atc 787 Val Val Ala Val Gly Ser Glu Glu Asp Val Val Lys Asp Ala Asp Ile 215 220 225 gtc atc gcc gcc acc acc acg gac gcc gcc ggc tcc tcc gcc ttc cca 835 Val Ile Ala Ala Thr Thr Thr Asp Ala Ala Gly Ser Ser Ala Phe Pro 230 235 240 245 tac ttc aaa aaa gaa tgg ctc aag ccg ggc gca ttg ctg ctg ctt cca 883 Tyr Phe Lys Lys Glu Trp Leu Lys Pro Gly Ala Leu Leu Leu Leu Pro 250 255 260 gcc gcc ggt cgc ttc gac gac gct tat ttg ctt gac gac gcc cgc ctc 931 Ala Ala Gly Arg Phe Asp Asp Ala Tyr Leu Leu Asp Asp Ala Arg Leu 265 270 275 gtt gtt gac tac atg ggg ctc tac gaa gcc tgg gca gaa gaa tac ggc 979 Val Val Asp Tyr Met Gly Leu Tyr Glu Ala Trp Ala Glu Glu Tyr Gly 280 285 290 cca cag gcc tac caa cta ctc ggc att cca gga acc cac tgg tac gac 1027 Pro Gln Ala Tyr Gln Leu Leu Gly Ile Pro Gly Thr His Trp Tyr Asp 295 300 305 ctg gcg ctg caa gga aaa ctc gac ctt gca aag att tcc cag att ggc 1075 Leu Ala Leu Gln Gly Lys Leu Asp Leu Ala Lys Ile Ser Gln Ile Gly 310 315 320 325 gat atc tgc tcc ggc aag cta ccc gga cgc acc aac gat gag gaa atc 1123 Asp Ile Cys Ser Gly Lys Leu Pro Gly Arg Thr Asn Asp Glu Glu Ile 330 335 340 atc ctc tat tcc gtc ggc ggc atg cca gta gaa gac gtc gcc tgg gca 1171 Ile Leu Tyr Ser Val Gly Gly Met Pro Val Glu Asp Val Ala Trp Ala 345 350 355 acc caa gtg tat gaa aac gcc ctg gaa aaa ggc gtc ggc acc aca ttg 1219 Thr Gln Val Tyr Glu Asn Ala Leu Glu Lys Gly Val Gly Thr Thr Leu 360 365 370 aac ctg tgg gaa tca ccc gca ctg gct tgagagaaga aacaacaatg 1266 Asn Leu Trp Glu Ser Pro Ala Leu Ala 375 380 aaa 1269 <210> 302 <211> 382 <212> PRT <213> Corynebacterium glutamicum <400> 302 Met Thr Ala Thr Tyr Thr Thr Glu Thr Ala Ile Asn Phe Leu Phe Leu 1 5 10 15 Ser Glu Pro Asp Met Ile Ala Ala Gly Val Lys Asp Val Ala Gln Cys 20 25 30 Val Asp Val Met Glu Glu Thr Leu Val Leu Leu Ala Gln Gly Asp Tyr 35 40 45 Lys Met Ala Gly Leu Asn Ser Asn Ser His Gly Ala Met Ile Thr Phe 50 55 60 Pro Glu Asn Pro Glu Phe Glu Gly Met Pro Lys Asp Gly Pro Asp Arg 65 70 75 80 Arg Phe Met Ala Met Pro Ala Tyr Leu Gly Gly Arg Phe Lys Asn Thr 85 90 95 Gly Val Lys Trp Tyr Gly Ser Asn Ala Glu Asn Lys Ala Ser Gly Leu 100 105 110 Pro Arg Ser Ile His Thr Phe Val Leu Asn Asp Thr Val Thr Gly Ala 115 120 125 Pro Lys Ala Ile Met Ser Ala Asn Leu Leu Ser Ala Tyr Arg Thr Gly 130 135 140 Ala Val Pro Gly Val Gly Val Lys His Leu Ala Val Ala Asp Ala Thr 145 150 155 160 Thr Leu Ala Val Val Gly Pro Gly Val Met Ala Lys Thr Ile Thr Glu 165 170 175 Ala Cys Ile Ala Glu Arg Pro Gly Ile Thr Thr Ile Lys Ile Lys Gly 180 185 190 Arg Ser Glu Arg Gly Ile Asn Ala Phe Ala Thr Trp Ala Leu Glu Lys 195 200 205 Phe Pro Glu Ile Glu Val Val Ala Val Gly Ser Glu Glu Asp Val Val 210 215 220 Lys Asp Ala Asp Ile Val Ile Ala Ala Thr Thr Thr Asp Ala Ala Gly 225 230 235 240 Ser Ser Ala Phe Pro Tyr Phe Lys Lys Glu Trp Leu Lys Pro Gly Ala 245 250 255 Leu Leu Leu Leu Pro Ala Ala Gly Arg Phe Asp Asp Ala Tyr Leu Leu 260 265 270 Asp Asp Ala Arg Leu Val Val Asp Tyr Met Gly Leu Tyr Glu Ala Trp 275 280 285 Ala Glu Glu Tyr Gly Pro Gln Ala Tyr Gln Leu Leu Gly Ile Pro Gly 290 295 300 Thr His Trp Tyr Asp Leu Ala Leu Gln Gly Lys Leu Asp Leu Ala Lys 305 310 315 320 Ile Ser Gln Ile Gly Asp Ile Cys Ser Gly Lys Leu Pro Gly Arg Thr 325 330 335 Asn Asp Glu Glu Ile Ile Leu Tyr Ser Val Gly Gly Met Pro Val Glu 340 345 350 Asp Val Ala Trp Ala Thr Gln Val Tyr Glu Asn Ala Leu Glu Lys Gly 355 360 365 Val Gly Thr Thr Leu Asn Leu Trp Glu Ser Pro Ala Leu Ala 370 375 380 <210> 303 <211> 1491 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1468) <223> RXS02970 <400> 303 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc gtg tgg ccg atg atc tcc ggc aac cga ttc cac 1363 Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser Gly Asn Arg Phe His 410 415 420 atc gcg ccg ccg ctg acc acc act gat gac gaa ttg gta gca ctg ctg 1411 Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu Leu Val Ala Leu Leu 425 430 435 gac gcg gtg gaa gct gca gcc caa gct gtc gag ctg acc ttc gct ggg 1459 Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu Leu Thr Phe Ala Gly 440 445 450 gcg ttg ttc taagttttct agataacaag gcc 1491 Ala Leu Phe 455 <210> 304 <211> 456 <212> PRT <213> Corynebacterium glutamicum <400> 304 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser 405 410 415 Gly Asn Arg Phe His Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu 420 425 430 Leu Val Ala Leu Leu Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu 435 440 445 Leu Thr Phe Ala Gly Ala Leu Phe 450 455 <210> 305 <211> 1330 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1330) <223> FRXA01009 <400> 305 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc 1330 Phe Lys Glu Arg Gly 410 <210> 306 <211> 410 <212> PRT <213> Corynebacterium glutamicum <400> 306 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly 405 410 <210> 307 <211> 3579 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3556) <223> RXN00023 <400> 307 gggattatgt tgggggccac atctgaaaat agttgctggg atccatcaca cctacgatgc 60 gaaacggcac ccacaccgct gatcttgaag gagaaccacc atg acg tcg atg aat 115 Met Thr Ser Met Asn 1 5 ctg cct att gag ttg gct acg ctg tct gac cag gct gtg gac aag gtg 163 Leu Pro Ile Glu Leu Ala Thr Leu Ser Asp Gln Ala Val Asp Lys Val 10 15 20 cgc tcc tgg ctg gag tac agc aaa aag gaa agc gtg ccc aat gcc gat 211 Arg Ser Trp Leu Glu Tyr Ser Lys Lys Glu Ser Val Pro Asn Ala Asp 25 30 35 gcg aag cgt cta gct gca gtg ttg cag gat cct aat ggt ttg gaa ttc 259 Ala Lys Arg Leu Ala Ala Val Leu Gln Asp Pro Asn Gly Leu Glu Phe 40 45 50 acg gtt ggt ttc gtg gat cga gtg gtt cga act gag gat cgt gaa gcg 307 Thr Val Gly Phe Val Asp Arg Val Val Arg Thr Glu Asp Arg Glu Ala 55 60 65 gca gcg cat gcg ttg tat gag ttg ggc aag att gct ccg tcg acg atg 355 Ala Ala His Ala Leu Tyr Glu Leu Gly Lys Ile Ala Pro Ser Thr Met 70 75 80 85 tcc ttt ttg gat cgg gcg cag att cag gcc ggt tct ttg gtg ggg cgg 403 Ser Phe Leu Asp Arg Ala Gln Ile Gln Ala Gly Ser Leu Val Gly Arg 90 95 100 gcg ttg ccg cag gtt gtg gtt cct gcg gcg cgg gct cga atc cgg cag 451 Ala Leu Pro Gln Val Val Val Pro Ala Ala Arg Ala Arg Ile Arg Gln 105 110 115 atg gtt ggg cac atg att gtg gat gcc cgc gac aag cag ttc gcc aag 499 Met Val Gly His Met Ile Val Asp Ala Arg Asp Lys Gln Phe Ala Lys 120 125 130 gct gtc gct gag att cag tcg gat ggg cac cgc ctg aac atc aat ttg 547 Ala Val Ala Glu Ile Gln Ser Asp Gly His Arg Leu Asn Ile Asn Leu 135 140 145 cta ggt gaa gcg gtg ttg ggc cga aag gag gca gcg aag cat ttg gat 595 Leu Gly Glu Ala Val Leu Gly Arg Lys Glu Ala Ala Lys His Leu Asp 150 155 160 165 gac acg gtg cgg ttg ttg cgc cgt ccg gat gtg gaa tat gtg tcc atc 643 Asp Thr Val Arg Leu Leu Arg Arg Pro Asp Val Glu Tyr Val Ser Ile 170 175 180 aag gtc tct tcg gtg gca tcg cag att tcg atg tgg ggt ttc gaa gac 691 Lys Val Ser Ser Val Ala Ser Gln Ile Ser Met Trp Gly Phe Glu Asp 185 190 195 acc gtt aat tat gtt gtg gaa cag ctg aca cct tta tat ata gag gcc 739 Thr Val Asn Tyr Val Val Glu Gln Leu Thr Pro Leu Tyr Ile Glu Ala 200 205 210 gcg cgg gcg ccg aaa ggc acg aag ttc atc aac ctg gac atg gag gaa 787 Ala Arg Ala Pro Lys Gly Thr Lys Phe Ile Asn Leu Asp Met Glu Glu 215 220 225 tac cgc gat ctg cgc ctg act atg gag gtg ttc aag cgg ctg ctc tcc 835 Tyr Arg Asp Leu Arg Leu Thr Met Glu Val Phe Lys Arg Leu Leu Ser 230 235 240 245 aat cca gag ctg cat gaa cta gaa gcc gga att gtg ttg cag gcg tac 883 Asn Pro Glu Leu His Glu Leu Glu Ala Gly Ile Val Leu Gln Ala Tyr 250 255 260 ctt ccc gat gcc ctc ggt gca atc cag gac ttg gcg cag ttc ggc cgc 931 Leu Pro Asp Ala Leu Gly Ala Ile Gln Asp Leu Ala Gln Phe Gly Arg 265 270 275 gag cgc gtc aac aca ggc ggg gcg ggc gtt aag gtt cgc ctg gtc aag 979 Glu Arg Val Asn Thr Gly Gly Ala Gly Val Lys Val Arg Leu Val Lys 280 285 290 ggt gct aat ttg cct atg gag cac gtc cac gcg cag atc acc ggc tgg 1027 Gly Ala Asn Leu Pro Met Glu His Val His Ala Gln Ile Thr Gly Trp 295 300 305 cca gtt gcc aca gaa cct tcc aaa caa gcc acc gat gcc aat tac aag 1075 Pro Val Ala Thr Glu Pro Ser Lys Gln Ala Thr Asp Ala Asn Tyr Lys 310 315 320 325 cgc gtc ctc tat tgg acg atg cgc aaa gaa aac atg gag ggc ctg cgc 1123 Arg Val Leu Tyr Trp Thr Met Arg Lys Glu Asn Met Glu Gly Leu Arg 330 335 340 ctg ggc gtt gcc ggc cac aac ctt ttc gac ata gca ttc gca cat ttg 1171 Leu Gly Val Ala Gly His Asn Leu Phe Asp Ile Ala Phe Ala His Leu 345 350 355 ctc tct gtg gag cgt ggg gta gcg gac cgt gtg gag ttc gaa atg ctg 1219 Leu Ser Val Glu Arg Gly Val Ala Asp Arg Val Glu Phe Glu Met Leu 360 365 370 cag ggc atg gcg tcc gat cag gcg cgc gcc gtc agc gtt gac gtc ggt 1267 Gln Gly Met Ala Ser Asp Gln Ala Arg Ala Val Ser Val Asp Val Gly 375 380 385 gag ctg ctg ctt tac gta cca gcc gtg cgc cca caa gaa ttc gac gtg 1315 Glu Leu Leu Leu Tyr Val Pro Ala Val Arg Pro Gln Glu Phe Asp Val 390 395 400 405 gcc att tct tac ctc gtg cgc cgc ctc gag gaa aac gcc gcg agc gaa 1363 Ala Ile Ser Tyr Leu Val Arg Arg Leu Glu Glu Asn Ala Ala Ser Glu 410 415 420 aac ttc atg tcc gcc atc ttc gac ctc gac gcc gac aac ccg tcc ttc 1411 Asn Phe Met Ser Ala Ile Phe Asp Leu Asp Ala Asp Asn Pro Ser Phe 425 430 435 aag cga gag gag agc cgc ttc cgc gcc tcc ata tct gac ctc gcc acg 1459 Lys Arg Glu Glu Ser Arg Phe Arg Ala Ser Ile Ser Asp Leu Ala Thr 440 445 450 ctc atc gac gtg ccc gcg ccc ggc ccc aac cac aca caa gac cgc agc 1507 Leu Ile Asp Val Pro Ala Pro Gly Pro Asn His Thr Gln Asp Arg Ser 455 460 465 aaa gag acg ctt ctc gac gcc ccc ctc gtc cca ttt atc aac gag ccc 1555 Lys Glu Thr Leu Leu Asp Ala Pro Leu Val Pro Phe Ile Asn Glu Pro 470 475 480 485 gac acc aac cca gcg ctc atc caa aac caa cag tgg gcc aca aaa gcc 1603 Asp Thr Asn Pro Ala Leu Ile Gln Asn Gln Gln Trp Ala Thr Lys Ala 490 495 500 gtc gcc acc gca gca gag ccc ggt tgg ttg gaa aaa caa aca aag ccg 1651 Val Ala Thr Ala Ala Glu Pro Gly Trp Leu Glu Lys Gln Thr Lys Pro 505 510 515 gag gtg ttg gaa gag ggg gac gtc gac aag cta att aac gat gtg cgc 1699 Glu Val Leu Glu Glu Gly Asp Val Asp Lys Leu Ile Asn Asp Val Arg 520 525 530 gac gct gct gaa gcg tgg gca gcg cgc cca gcc cgt gaa cgc gct gag 1747 Asp Ala Ala Glu Ala Trp Ala Ala Arg Pro Ala Arg Glu Arg Ala Glu 535 540 545 att ttg tac aag acc gcc gag att ttg cgc gtg cga cgc gga cac ctg 1795 Ile Leu Tyr Lys Thr Ala Glu Ile Leu Arg Val Arg Arg Gly His Leu 550 555 560 565 atc tca gtg acg gcc gcg gag gtg ggc aaa gct gtg gaa caa acc gac 1843 Ile Ser Val Thr Ala Ala Glu Val Gly Lys Ala Val Glu Gln Thr Asp 570 575 580 ccg gaa atc tct gaa gcc att gat ttc gcc cgc tac tac gcg cat ttg 1891 Pro Glu Ile Ser Glu Ala Ile Asp Phe Ala Arg Tyr Tyr Ala His Leu 585 590 595 gcc ctg gaa ttg gac gac gta gac aat gcg gaa ttc acc cca gat cgc 1939 Ala Leu Glu Leu Asp Asp Val Asp Asn Ala Glu Phe Thr Pro Asp Arg 600 605 610 gtc gtt gtg gtg acc ccg ccc tgg aat ttc ccc atc gcg atc ccc gct 1987 Val Val Val Val Thr Pro Pro Trp Asn Phe Pro Ile Ala Ile Pro Ala 615 620 625 gga tcg act ttc gca gca ctc gcg gcg ggc gct ggc gtg atc cac aaa 2035 Gly Ser Thr Phe Ala Ala Leu Ala Ala Gly Ala Gly Val Ile His Lys 630 635 640 645 ccc tca aag cct agc caa cat tgc tcc gct gca gtg gtc gaa gcc ctc 2083 Pro Ser Lys Pro Ser Gln His Cys Ser Ala Ala Val Val Glu Ala Leu 650 655 660 tgg gaa gcc ggc gtt ccc cgc gag gtt ctg cat tgc att tac cca gct 2131 Trp Glu Ala Gly Val Pro Arg Glu Val Leu His Cys Ile Tyr Pro Ala 665 670 675 aat cgc gat gtt gga tgt gcg ttg atc agc cat gaa cac gtc gac cgc 2179 Asn Arg Asp Val Gly Cys Ala Leu Ile Ser His Glu His Val Asp Arg 680 685 690 gtc att ttg acc ggc tcc tcc gag acc gcc gcg atg ttc tcc tcc tgg 2227 Val Ile Leu Thr Gly Ser Ser Glu Thr Ala Ala Met Phe Ser Ser Trp 695 700 705 cga cca gaa ctc acc atc aac ggc gaa acc tcc ggc aaa aac gcc atc 2275 Arg Pro Glu Leu Thr Ile Asn Gly Glu Thr Ser Gly Lys Asn Ala Ile 710 715 720 725 gtg gtc acc cca tct gcc gac cgc gac ctc gcc gtc gcc gac ctg gtg 2323 Val Val Thr Pro Ser Ala Asp Arg Asp Leu Ala Val Ala Asp Leu Val 730 735 740 aaa tcc gcc ttc ggc cat gca gga caa aaa tgt tcc gca gcc tcc ctc 2371 Lys Ser Ala Phe Gly His Ala Gly Gln Lys Cys Ser Ala Ala Ser Leu 745 750 755 ggc atc ttg gta ggc agc gtc tac gaa tca gaa cgc ttc cgg aaa cag 2419 Gly Ile Leu Val Gly Ser Val Tyr Glu Ser Glu Arg Phe Arg Lys Gln 760 765 770 ctg gta gac gcc gca tcc tca ctc atc gtc gac tgg cct acc aac ccc 2467 Leu Val Asp Ala Ala Ser Ser Leu Ile Val Asp Trp Pro Thr Asn Pro 775 780 785 tcc gca acc gtc gga cca ctc acc gaa ctc ccc agc gat aaa ctc cac 2515 Ser Ala Thr Val Gly Pro Leu Thr Glu Leu Pro Ser Asp Lys Leu His 790 795 800 805 cac gcc cta acc acc ctc gaa gaa gga gaa agc tgg ctg ctg aaa ccc 2563 His Ala Leu Thr Thr Leu Glu Glu Gly Glu Ser Trp Leu Leu Lys Pro 810 815 820 cga caa ctc gac gac acc ggc cga ctc tgg tca ccc ggc atc aaa gaa 2611 Arg Gln Leu Asp Asp Thr Gly Arg Leu Trp Ser Pro Gly Ile Lys Glu 825 830 835 ggc gtc aaa cca gga acc ttc ttc cac ctc aca gaa gta ttc gga cca 2659 Gly Val Lys Pro Gly Thr Phe Phe His Leu Thr Glu Val Phe Gly Pro 840 845 850 gtc ctc ggc ctg atg aaa gcc acc gac ctc aat gaa gcc atc gaa ttc 2707 Val Leu Gly Leu Met Lys Ala Thr Asp Leu Asn Glu Ala Ile Glu Phe 855 860 865 caa aac ggc aac gac ttc gga ctc acc ggc gga ctc caa tcc ctc gac 2755 Gln Asn Gly Asn Asp Phe Gly Leu Thr Gly Gly Leu Gln Ser Leu Asp 870 875 880 885 gcc gac gaa gtc cgc acc tgg ctt gac cac gtc gat gtc gga aac gcc 2803 Ala Asp Glu Val Arg Thr Trp Leu Asp His Val Asp Val Gly Asn Ala 890 895 900 tac gtc aac cgc ggc atc acc ggc gcc att gtc caa cgc caa tcc ttc 2851 Tyr Val Asn Arg Gly Ile Thr Gly Ala Ile Val Gln Arg Gln Ser Phe 905 910 915 gga ggc tgg aaa aaa tcc tcc gtc ggc ctc gga tcc aaa gcc gga gga 2899 Gly Gly Trp Lys Lys Ser Ser Val Gly Leu Gly Ser Lys Ala Gly Gly 920 925 930 ccc aac tat gtc atg ctc atg gga acc tgg gcc gac gcg cca agc cac 2947 Pro Asn Tyr Val Met Leu Met Gly Thr Trp Ala Asp Ala Pro Ser His 935 940 945 cac gcc cca cgc gaa aca aac ccg ctg atc agc aaa ctg gat ctc ccc 2995 His Ala Pro Arg Glu Thr Asn Pro Leu Ile Ser Lys Leu Asp Leu Pro 950 955 960 965 gga gaa gag ctc gaa tgg ctc gaa aaa gcc aac gcc agc gat gaa aca 3043 Gly Glu Glu Leu Glu Trp Leu Glu Lys Ala Asn Ala Ser Asp Glu Thr 970 975 980 gca tgg aac acg gaa ttc ggc agc cca cgc gac ccc tcc ggc ctc gat 3091 Ala Trp Asn Thr Glu Phe Gly Ser Pro Arg Asp Pro Ser Gly Leu Asp 985 990 995 gta gaa gcc aac att ttc cgc tac cga cca gca gag gta gta ctc cga 3139 Val Glu Ala Asn Ile Phe Arg Tyr Arg Pro Ala Glu Val Val Leu Arg 1000 1005 1010 ctc gac gat tcc gcc aca ccc cga gaa act gcc cgc gca ttg ttg gca 3187 Leu Asp Asp Ser Ala Thr Pro Arg Glu Thr Ala Arg Ala Leu Leu Ala 1015 1020 1025 gcc cgt cgc gcc ggg gtt act ccg cga gtt ctt caa aca cca ggt gtt 3235 Ala Arg Arg Ala Gly Val Thr Pro Arg Val Leu Gln Thr Pro Gly Val 1030 1035 1040 1045 tca gag caa gtc cgc gaa gta ttg tcc gct gct gga gtg agt gca gaa 3283 Ser Glu Gln Val Arg Glu Val Leu Ser Ala Ala Gly Val Ser Ala Glu 1050 1055 1060 aca gtc gat gat tcg gta ttt att tcc aac gtg ttg cgc ggc gaa tac 3331 Thr Val Asp Asp Ser Val Phe Ile Ser Asn Val Leu Arg Gly Glu Tyr 1065 1070 1075 gac gag aac tcc agc gtc cga gtc cgc tac ctg ggc aaa gtt agc gac 3379 Asp Glu Asn Ser Ser Val Arg Val Arg Tyr Leu Gly Lys Val Ser Asp 1080 1085 1090 act gtc cgt gaa cgc cta tct gta cgg ccc gaa gtt gtt ctg ctt gac 3427 Thr Val Arg Glu Arg Leu Ser Val Arg Pro Glu Val Val Leu Leu Asp 1095 1100 1105 gat gca gta act gcc tcc ggt cga gtt gaa tta cgt tac tgg ctc aaa 3475 Asp Ala Val Thr Ala Ser Gly Arg Val Glu Leu Arg Tyr Trp Leu Lys 1110 1115 1120 1125 gaa caa gca att tcc atg acg ttg cac cgt ttt gga aac cca gtt gcg 3523 Glu Gln Ala Ile Ser Met Thr Leu His Arg Phe Gly Asn Pro Val Ala 1130 1135 1140 gcc ttc cac gag ttg gcg gag gaa ctt aaa cgt tgatcgtttt gcgcatgggt 3576 Ala Phe His Glu Leu Ala Glu Glu Leu Lys Arg 1145 1150 cgc 3579 <210> 308 <211> 1152 <212> PRT <213> Corynebacterium glutamicum <400> 308 Met Thr Ser Met Asn Leu Pro Ile Glu Leu Ala Thr Leu Ser Asp Gln 1 5 10 15 Ala Val Asp Lys Val Arg Ser Trp Leu Glu Tyr Ser Lys Lys Glu Ser 20 25 30 Val Pro Asn Ala Asp Ala Lys Arg Leu Ala Ala Val Leu Gln Asp Pro 35 40 45 Asn Gly Leu Glu Phe Thr Val Gly Phe Val Asp Arg Val Val Arg Thr 50 55 60 Glu Asp Arg Glu Ala Ala Ala His Ala Leu Tyr Glu Leu Gly Lys Ile 65 70 75 80 Ala Pro Ser Thr Met Ser Phe Leu Asp Arg Ala Gln Ile Gln Ala Gly 85 90 95 Ser Leu Val Gly Arg Ala Leu Pro Gln Val Val Val Pro Ala Ala Arg 100 105 110 Ala Arg Ile Arg Gln Met Val Gly His Met Ile Val Asp Ala Arg Asp 115 120 125 Lys Gln Phe Ala Lys Ala Val Ala Glu Ile Gln Ser Asp Gly His Arg 130 135 140 Leu Asn Ile Asn Leu Leu Gly Glu Ala Val Leu Gly Arg Lys Glu Ala 145 150 155 160 Ala Lys His Leu Asp Asp Thr Val Arg Leu Leu Arg Arg Pro Asp Val 165 170 175 Glu Tyr Val Ser Ile Lys Val Ser Ser Val Ala Ser Gln Ile Ser Met 180 185 190 Trp Gly Phe Glu Asp Thr Val Asn Tyr Val Val Glu Gln Leu Thr Pro 195 200 205 Leu Tyr Ile Glu Ala Ala Arg Ala Pro Lys Gly Thr Lys Phe Ile Asn 210 215 220 Leu Asp Met Glu Glu Tyr Arg Asp Leu Arg Leu Thr Met Glu Val Phe 225 230 235 240 Lys Arg Leu Leu Ser Asn Pro Glu Leu His Glu Leu Glu Ala Gly Ile 245 250 255 Val Leu Gln Ala Tyr Leu Pro Asp Ala Leu Gly Ala Ile Gln Asp Leu 260 265 270 Ala Gln Phe Gly Arg Glu Arg Val Asn Thr Gly Gly Ala Gly Val Lys 275 280 285 Val Arg Leu Val Lys Gly Ala Asn Leu Pro Met Glu His Val His Ala 290 295 300 Gln Ile Thr Gly Trp Pro Val Ala Thr Glu Pro Ser Lys Gln Ala Thr 305 310 315 320 Asp Ala Asn Tyr Lys Arg Val Leu Tyr Trp Thr Met Arg Lys Glu Asn 325 330 335 Met Glu Gly Leu Arg Leu Gly Val Ala Gly His Asn Leu Phe Asp Ile 340 345 350 Ala Phe Ala His Leu Leu Ser Val Glu Arg Gly Val Ala Asp Arg Val 355 360 365 Glu Phe Glu Met Leu Gln Gly Met Ala Ser Asp Gln Ala Arg Ala Val 370 375 380 Ser Val Asp Val Gly Glu Leu Leu Leu Tyr Val Pro Ala Val Arg Pro 385 390 395 400 Gln Glu Phe Asp Val Ala Ile Ser Tyr Leu Val Arg Arg Leu Glu Glu 405 410 415 Asn Ala Ala Ser Glu Asn Phe Met Ser Ala Ile Phe Asp Leu Asp Ala 420 425 430 Asp Asn Pro Ser Phe Lys Arg Glu Glu Ser Arg Phe Arg Ala Ser Ile 435 440 445 Ser Asp Leu Ala Thr Leu Ile Asp Val Pro Ala Pro Gly Pro Asn His 450 455 460 Thr Gln Asp Arg Ser Lys Glu Thr Leu Leu Asp Ala Pro Leu Val Pro 465 470 475 480 Phe Ile Asn Glu Pro Asp Thr Asn Pro Ala Leu Ile Gln Asn Gln Gln 485 490 495 Trp Ala Thr Lys Ala Val Ala Thr Ala Ala Glu Pro Gly Trp Leu Glu 500 505 510 Lys Gln Thr Lys Pro Glu Val Leu Glu Glu Gly Asp Val Asp Lys Leu 515 520 525 Ile Asn Asp Val Arg Asp Ala Ala Glu Ala Trp Ala Ala Arg Pro Ala 530 535 540 Arg Glu Arg Ala Glu Ile Leu Tyr Lys Thr Ala Glu Ile Leu Arg Val 545 550 555 560 Arg Arg Gly His Leu Ile Ser Val Thr Ala Ala Glu Val Gly Lys Ala 565 570 575 Val Glu Gln Thr Asp Pro Glu Ile Ser Glu Ala Ile Asp Phe Ala Arg 580 585 590 Tyr Tyr Ala His Leu Ala Leu Glu Leu Asp Asp Val Asp Asn Ala Glu 595 600 605 Phe Thr Pro Asp Arg Val Val Val Val Thr Pro Pro Trp Asn Phe Pro 610 615 620 Ile Ala Ile Pro Ala Gly Ser Thr Phe Ala Ala Leu Ala Ala Gly Ala 625 630 635 640 Gly Val Ile His Lys Pro Ser Lys Pro Ser Gln His Cys Ser Ala Ala 645 650 655 Val Val Glu Ala Leu Trp Glu Ala Gly Val Pro Arg Glu Val Leu His 660 665 670 Cys Ile Tyr Pro Ala Asn Arg Asp Val Gly Cys Ala Leu Ile Ser His 675 680 685 Glu His Val Asp Arg Val Ile Leu Thr Gly Ser Ser Glu Thr Ala Ala 690 695 700 Met Phe Ser Ser Trp Arg Pro Glu Leu Thr Ile Asn Gly Glu Thr Ser 705 710 715 720 Gly Lys Asn Ala Ile Val Val Thr Pro Ser Ala Asp Arg Asp Leu Ala 725 730 735 Val Ala Asp Leu Val Lys Ser Ala Phe Gly His Ala Gly Gln Lys Cys 740 745 750 Ser Ala Ala Ser Leu Gly Ile Leu Val Gly Ser Val Tyr Glu Ser Glu 755 760 765 Arg Phe Arg Lys Gln Leu Val Asp Ala Ala Ser Ser Leu Ile Val Asp 770 775 780 Trp Pro Thr Asn Pro Ser Ala Thr Val Gly Pro Leu Thr Glu Leu Pro 785 790 795 800 Ser Asp Lys Leu His His Ala Leu Thr Thr Leu Glu Glu Gly Glu Ser 805 810 815 Trp Leu Leu Lys Pro Arg Gln Leu Asp Asp Thr Gly Arg Leu Trp Ser 820 825 830 Pro Gly Ile Lys Glu Gly Val Lys Pro Gly Thr Phe Phe His Leu Thr 835 840 845 Glu Val Phe Gly Pro Val Leu Gly Leu Met Lys Ala Thr Asp Leu Asn 850 855 860 Glu Ala Ile Glu Phe Gln Asn Gly Asn Asp Phe Gly Leu Thr Gly Gly 865 870 875 880 Leu Gln Ser Leu Asp Ala Asp Glu Val Arg Thr Trp Leu Asp His Val 885 890 895 Asp Val Gly Asn Ala Tyr Val Asn Arg Gly Ile Thr Gly Ala Ile Val 900 905 910 Gln Arg Gln Ser Phe Gly Gly Trp Lys Lys Ser Ser Val Gly Leu Gly 915 920 925 Ser Lys Ala Gly Gly Pro Asn Tyr Val Met Leu Met Gly Thr Trp Ala 930 935 940 Asp Ala Pro Ser His His Ala Pro Arg Glu Thr Asn Pro Leu Ile Ser 945 950 955 960 Lys Leu Asp Leu Pro Gly Glu Glu Leu Glu Trp Leu Glu Lys Ala Asn 965 970 975 Ala Ser Asp Glu Thr Ala Trp Asn Thr Glu Phe Gly Ser Pro Arg Asp 980 985 990 Pro Ser Gly Leu Asp Val Glu Ala Asn Ile Phe Arg Tyr Arg Pro Ala 995 1000 1005 Glu Val Val Leu Arg Leu Asp Asp Ser Ala Thr Pro Arg Glu Thr Ala 1010 1015 1020 Arg Ala Leu Leu Ala Ala Arg Arg Ala Gly Val Thr Pro Arg Val Leu 1025 1030 1035 1040 Gln Thr Pro Gly Val Ser Glu Gln Val Arg Glu Val Leu Ser Ala Ala 1045 1050 1055 Gly Val Ser Ala Glu Thr Val Asp Asp Ser Val Phe Ile Ser Asn Val 1060 1065 1070 Leu Arg Gly Glu Tyr Asp Glu Asn Ser Ser Val Arg Val Arg Tyr Leu 1075 1080 1085 Gly Lys Val Ser Asp Thr Val Arg Glu Arg Leu Ser Val Arg Pro Glu 1090 1095 1100 Val Val Leu Leu Asp Asp Ala Val Thr Ala Ser Gly Arg Val Glu Leu 1105 1110 1115 1120 Arg Tyr Trp Leu Lys Glu Gln Ala Ile Ser Met Thr Leu His Arg Phe 1125 1130 1135 Gly Asn Pro Val Ala Ala Phe His Glu Leu Ala Glu Glu Leu Lys Arg 1140 1145 1150 <210> 309 <211> 476 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(453) <223> FRXA00023 <400> 309 cat ttt ccg ctc cga cca gca gag gta gta ctc cga ctc gac gat tcc 48 His Phe Pro Leu Arg Pro Ala Glu Val Val Leu Arg Leu Asp Asp Ser 1 5 10 15 gcc aca ccc cga gaa act gcc cgc gca ttg ttg gca gcc cgt cgc gcc 96 Ala Thr Pro Arg Glu Thr Ala Arg Ala Leu Leu Ala Ala Arg Arg Ala 20 25 30 ggg gtt act ccg cga gtt ctt caa aca cca ggt gtt tca gag caa gtc 144 Gly Val Thr Pro Arg Val Leu Gln Thr Pro Gly Val Ser Glu Gln Val 35 40 45 cgc gaa gta ttg tcc gct gct gga gtg agt gca gaa aca gtc gat gat 192 Arg Glu Val Leu Ser Ala Ala Gly Val Ser Ala Glu Thr Val Asp Asp 50 55 60 tcg gta ttt att tcc aac gtg ttg cgc ggc gaa tac gac gag aac tcc 240 Ser Val Phe Ile Ser Asn Val Leu Arg Gly Glu Tyr Asp Glu Asn Ser 65 70 75 80 agc gtc cga gtc cgc tac ctg ggc aaa gtt agc gac act gtc cgt gaa 288 Ser Val Arg Val Arg Tyr Leu Gly Lys Val Ser Asp Thr Val Arg Glu 85 90 95 cgc cta tct gta cgg ccc gaa gtt gtt ctg ctt gac gat gca gta act 336 Arg Leu Ser Val Arg Pro Glu Val Val Leu Leu Asp Asp Ala Val Thr 100 105 110 gcc tcc ggt cga gtt gaa tta cgt tac tgg ctc aaa gaa caa gca att 384 Ala Ser Gly Arg Val Glu Leu Arg Tyr Trp Leu Lys Glu Gln Ala Ile 115 120 125 tcc atg acg ttg cac cgt ttt gga aac cca gtt gcg gcc ttc cac gag 432 Ser Met Thr Leu His Arg Phe Gly Asn Pro Val Ala Ala Phe His Glu 130 135 140 ttg gcg gag gaa ctt aaa cgt tgatcgtttt gcgcatgggt cgc 476 Leu Ala Glu Glu Leu Lys Arg 145 150 <210> 310 <211> 151 <212> PRT <213> Corynebacterium glutamicum <400> 310 His Phe Pro Leu Arg Pro Ala Glu Val Val Leu Arg Leu Asp Asp Ser 1 5 10 15 Ala Thr Pro Arg Glu Thr Ala Arg Ala Leu Leu Ala Ala Arg Arg Ala 20 25 30 Gly Val Thr Pro Arg Val Leu Gln Thr Pro Gly Val Ser Glu Gln Val 35 40 45 Arg Glu Val Leu Ser Ala Ala Gly Val Ser Ala Glu Thr Val Asp Asp 50 55 60 Ser Val Phe Ile Ser Asn Val Leu Arg Gly Glu Tyr Asp Glu Asn Ser 65 70 75 80 Ser Val Arg Val Arg Tyr Leu Gly Lys Val Ser Asp Thr Val Arg Glu 85 90 95 Arg Leu Ser Val Arg Pro Glu Val Val Leu Leu Asp Asp Ala Val Thr 100 105 110 Ala Ser Gly Arg Val Glu Leu Arg Tyr Trp Leu Lys Glu Gln Ala Ile 115 120 125 Ser Met Thr Leu His Arg Phe Gly Asn Pro Val Ala Ala Phe His Glu 130 135 140 Leu Ala Glu Glu Leu Lys Arg 145 150 <210> 311 <211> 3124 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3124) <223> FRXA02284 <220> <221> misc_feature <222> 641 - 647 <223> n = a, c, g, or t <220> <221> VARIANT <222> 181, 182 <223> Xaa = any amino acid <220> <221> VARIANT <222> 183 <223> Xaa = Phe, Ser, Tyr, or Cys <400> 311 gggattatgt tgggggccac atctgaaaat agttgctggg atccatcaca cctacgatgc 60 gaaacggcac ccacaccgct gatcttgaag gagaaccacc atg acg tcg atg aat 115 Met Thr Ser Met Asn 1 5 ctg cct att gag ttg gct acg ctg tct gac cag gct gtg gac aag gtg 163 Leu Pro Ile Glu Leu Ala Thr Leu Ser Asp Gln Ala Val Asp Lys Val 10 15 20 cgc tcc tgg ctg gag tac agc aaa aag gaa agc gtg ccc aat gcc gat 211 Arg Ser Trp Leu Glu Tyr Ser Lys Lys Glu Ser Val Pro Asn Ala Asp 25 30 35 gcg aag cgt cta gct gca gtg ttg cag gat cct aat ggt ttg gaa ttc 259 Ala Lys Arg Leu Ala Ala Val Leu Gln Asp Pro Asn Gly Leu Glu Phe 40 45 50 acg gtt ggt ttc gtg gat cga gtg gtt cga act gag gat cgt gaa gcg 307 Thr Val Gly Phe Val Asp Arg Val Val Arg Thr Glu Asp Arg Glu Ala 55 60 65 gca gcg cat gcg ttg tat gag ttg ggc aag att gct ccg tcg acg atg 355 Ala Ala His Ala Leu Tyr Glu Leu Gly Lys Ile Ala Pro Ser Thr Met 70 75 80 85 tcc ttt ttg gat cgg gcg cag att cag gcc ggt tct ttg gtg ggg cgg 403 Ser Phe Leu Asp Arg Ala Gln Ile Gln Ala Gly Ser Leu Val Gly Arg 90 95 100 gcg ttg ccg cag gtt gtg gtt cct gcg gcg cgg gct cga atc cgg cag 451 Ala Leu Pro Gln Val Val Val Pro Ala Ala Arg Ala Arg Ile Arg Gln 105 110 115 atg gtt ggg cac atg att gtg gat gcc cgc gac aag cag ttc gcc aag 499 Met Val Gly His Met Ile Val Asp Ala Arg Asp Lys Gln Phe Ala Lys 120 125 130 gct gtc gct gag att cag tcg gat ggg cac cgc ctg aac atc aat ttg 547 Ala Val Ala Glu Ile Gln Ser Asp Gly His Arg Leu Asn Ile Asn Leu 135 140 145 cta ggt gaa gcg gtg ttg ggc cga aag gaa gca gcg aag cat ttg gat 595 Leu Gly Glu Ala Val Leu Gly Arg Lys Glu Ala Ala Lys His Leu Asp 150 155 160 165 gac acg gtg cgg ttg ttg cgc cgt ccg gat gtg gaa tat gtg tcn nnn 643 Asp Thr Val Arg Leu Leu Arg Arg Pro Asp Val Glu Tyr Val Ser Xaa 170 175 180 nnn ntc tct tcg gtg gca tcg cag att tcg atg tgg ggt ttc gaa gac 691 Xaa Xaa Ser Ser Val Ala Ser Gln Ile Ser Met Trp Gly Phe Glu Asp 185 190 195 acc gtt aat tat gtt gtg gaa cag ctg aca cct tta tat ata gag ccc 739 Thr Val Asn Tyr Val Val Glu Gln Leu Thr Pro Leu Tyr Ile Glu Pro 200 205 210 gcg cgg gcg ccg aaa ggc acg aag ttc atc aac ctg gac atg gag gaa 787 Ala Arg Ala Pro Lys Gly Thr Lys Phe Ile Asn Leu Asp Met Glu Glu 215 220 225 tac cgc gat ctg cgc ctg act atg gag gtg ttc aag cgg ctg ctc tcc 835 Tyr Arg Asp Leu Arg Leu Thr Met Glu Val Phe Lys Arg Leu Leu Ser 230 235 240 245 aat cca gag ctg cat gaa cta gaa gcc gga att gtg ttg cag gcg tac 883 Asn Pro Glu Leu His Glu Leu Glu Ala Gly Ile Val Leu Gln Ala Tyr 250 255 260 ctt ccc gat gcc ctc ggt gca atc cag gac ttg gcg cag ttc ggc cgc 931 Leu Pro Asp Ala Leu Gly Ala Ile Gln Asp Leu Ala Gln Phe Gly Arg 265 270 275 gag cgc gtc aac aca ggc ggg gcg ggc gtt aag gtt cgc ctg gtc aag 979 Glu Arg Val Asn Thr Gly Gly Ala Gly Val Lys Val Arg Leu Val Lys 280 285 290 ggt gct aat ttg cct atg gag cac gtc cac gcg cag atc acc ggc tgg 1027 Gly Ala Asn Leu Pro Met Glu His Val His Ala Gln Ile Thr Gly Trp 295 300 305 cca gtt gcc aca gaa cct tcc aaa caa gcc acc gat gcc aat tac aag 1075 Pro Val Ala Thr Glu Pro Ser Lys Gln Ala Thr Asp Ala Asn Tyr Lys 310 315 320 325 cgc gtc ctc tat tgg acg atg cgc aaa gaa aac atg gag ggc ctg cgc 1123 Arg Val Leu Tyr Trp Thr Met Arg Lys Glu Asn Met Glu Gly Leu Arg 330 335 340 ctg ggc gtt gcc ggc cac aac ctt ttc gac ata gca ttc gca cat ttg 1171 Leu Gly Val Ala Gly His Asn Leu Phe Asp Ile Ala Phe Ala His Leu 345 350 355 ctc tct gtg gag cgt ggg gta gcg gac cgt gtg gag ttc gaa atg ctg 1219 Leu Ser Val Glu Arg Gly Val Ala Asp Arg Val Glu Phe Glu Met Leu 360 365 370 cag ggc atg gcg tcc gat cag gcg cgc gcc gtc agc gtt gac gtc ggt 1267 Gln Gly Met Ala Ser Asp Gln Ala Arg Ala Val Ser Val Asp Val Gly 375 380 385 gag ctg ctg ctt tac gta cca gcc gtg cgc cca caa gaa ttc gac gtg 1315 Glu Leu Leu Leu Tyr Val Pro Ala Val Arg Pro Gln Glu Phe Asp Val 390 395 400 405 gcc att tct tac ctc gtg cgc cgc ctc gag gaa aac gcc gcg agc gaa 1363 Ala Ile Ser Tyr Leu Val Arg Arg Leu Glu Glu Asn Ala Ala Ser Glu 410 415 420 aac ttc atg tcc gcc atc ttc gac ctc gac gcc gac aac ccg tcc ttc 1411 Asn Phe Met Ser Ala Ile Phe Asp Leu Asp Ala Asp Asn Pro Ser Phe 425 430 435 aag cga gag gag agc cgc ttc cgc gcc tcc ata tct gac ctc gcc acg 1459 Lys Arg Glu Glu Ser Arg Phe Arg Ala Ser Ile Ser Asp Leu Ala Thr 440 445 450 ctc atc gac gtg ccc gcg ccc ggc ccc aac cac aca caa gac cgc agc 1507 Leu Ile Asp Val Pro Ala Pro Gly Pro Asn His Thr Gln Asp Arg Ser 455 460 465 aaa gag acg ctt ctc gac gcc ccc ctc gtc cca ttt atc aac gag ccc 1555 Lys Glu Thr Leu Leu Asp Ala Pro Leu Val Pro Phe Ile Asn Glu Pro 470 475 480 485 gac acc aac cca gcg ctc atc caa aac caa cag tgg gcc aca aaa gcc 1603 Asp Thr Asn Pro Ala Leu Ile Gln Asn Gln Gln Trp Ala Thr Lys Ala 490 495 500 gtc gcc acc gca gca gag ccc ggt tgg ttg gaa aaa caa aca aag ccg 1651 Val Ala Thr Ala Ala Glu Pro Gly Trp Leu Glu Lys Gln Thr Lys Pro 505 510 515 gag gtg ttg gaa gag ggg gac gtc gac aag cta att aac gat gtg cgc 1699 Glu Val Leu Glu Glu Gly Asp Val Asp Lys Leu Ile Asn Asp Val Arg 520 525 530 gac gct gct gaa gcg tgg gca gcg cgc cca gcc cgt gaa cgc gct gag 1747 Asp Ala Ala Glu Ala Trp Ala Ala Arg Pro Ala Arg Glu Arg Ala Glu 535 540 545 att ttg tac aag acc gcc gag att ttg cgc gtg cga cgc gga cac ctg 1795 Ile Leu Tyr Lys Thr Ala Glu Ile Leu Arg Val Arg Arg Gly His Leu 550 555 560 565 atc tca gtg acg gcc gcg gag gtg ggc aaa gct gtg gaa caa acc gac 1843 Ile Ser Val Thr Ala Ala Glu Val Gly Lys Ala Val Glu Gln Thr Asp 570 575 580 ccg gaa atc tct gaa gcc att gat ttc gcc cgc tac tac gcg cat ttg 1891 Pro Glu Ile Ser Glu Ala Ile Asp Phe Ala Arg Tyr Tyr Ala His Leu 585 590 595 gcc ctg gaa ttg gac gac gta gac aat gcg gaa ttc acc cca gat cgc 1939 Ala Leu Glu Leu Asp Asp Val Asp Asn Ala Glu Phe Thr Pro Asp Arg 600 605 610 gtc gtt gtg gtg acc ccg ccc tgg aat ttc ccc atc gcg atc ccc gct 1987 Val Val Val Val Thr Pro Pro Trp Asn Phe Pro Ile Ala Ile Pro Ala 615 620 625 gga tcg act ttc gca gca ctc gcg gcg ggc gct ggc gtg atc cac aaa 2035 Gly Ser Thr Phe Ala Ala Leu Ala Ala Gly Ala Gly Val Ile His Lys 630 635 640 645 ccc tca aag cct agc caa cat tgc tcc gct gca gtg gtc gaa gcc ctc 2083 Pro Ser Lys Pro Ser Gln His Cys Ser Ala Ala Val Val Glu Ala Leu 650 655 660 tgg gaa gcc ggc gtt ccc cgc gag gtt ctg cat tgc att tac cca gct 2131 Trp Glu Ala Gly Val Pro Arg Glu Val Leu His Cys Ile Tyr Pro Ala 665 670 675 aat cgc gat gtt gga tgt gcg ttg atc agc cat gaa cac gtc gac cgc 2179 Asn Arg Asp Val Gly Cys Ala Leu Ile Ser His Glu His Val Asp Arg 680 685 690 gtc att ttg acc ggc tcc tcc gag acc gcc gcg atg ttc tcc tcc tgg 2227 Val Ile Leu Thr Gly Ser Ser Glu Thr Ala Ala Met Phe Ser Ser Trp 695 700 705 cga cca gaa ctc acc atc aac ggc gaa acc tcc ggc aaa aac gcc atc 2275 Arg Pro Glu Leu Thr Ile Asn Gly Glu Thr Ser Gly Lys Asn Ala Ile 710 715 720 725 gtg gtc acc cca tct gcc gac cgc gac ctc gcc gtc gcc gac ctg gtg 2323 Val Val Thr Pro Ser Ala Asp Arg Asp Leu Ala Val Ala Asp Leu Val 730 735 740 aaa tcc gcc ttc ggc cat gca gga caa aaa tgt tcc gca gcc tcc ctc 2371 Lys Ser Ala Phe Gly His Ala Gly Gln Lys Cys Ser Ala Ala Ser Leu 745 750 755 ggc atc ttg gta ggc agc gtc tac gaa tca gaa cgc ttc cgg aaa cag 2419 Gly Ile Leu Val Gly Ser Val Tyr Glu Ser Glu Arg Phe Arg Lys Gln 760 765 770 ctg gta gac gcc gca tcc tca ctc atc gtc gac tgg cct acc aac ccc 2467 Leu Val Asp Ala Ala Ser Ser Leu Ile Val Asp Trp Pro Thr Asn Pro 775 780 785 tcc gca acc gtc gga cca ctc acc gaa ctc ccc agc gat aaa ctc cac 2515 Ser Ala Thr Val Gly Pro Leu Thr Glu Leu Pro Ser Asp Lys Leu His 790 795 800 805 cac gcc cta acc acc ctc gaa gaa gga gaa agc tgg ctg ctg aaa ccc 2563 His Ala Leu Thr Thr Leu Glu Glu Gly Glu Ser Trp Leu Leu Lys Pro 810 815 820 cga caa ctc gac gac acc ggc cga ctc tgg tca ccc ggc atc aaa gaa 2611 Arg Gln Leu Asp Asp Thr Gly Arg Leu Trp Ser Pro Gly Ile Lys Glu 825 830 835 ggc gtc aaa cca gga acc ttc ttc cac ctc aca gaa gta ttc gga cca 2659 Gly Val Lys Pro Gly Thr Phe Phe His Leu Thr Glu Val Phe Gly Pro 840 845 850 gtc ctc ggc ctg atg aaa gcc acc gac ctc aat gaa gcc atc gaa ttc 2707 Val Leu Gly Leu Met Lys Ala Thr Asp Leu Asn Glu Ala Ile Glu Phe 855 860 865 caa aac ggc aac gac ttc gga ctc acc ggc gga ctc caa tcc ctc gac 2755 Gln Asn Gly Asn Asp Phe Gly Leu Thr Gly Gly Leu Gln Ser Leu Asp 870 875 880 885 gcc gac gaa gtc cgc acc tgg ctt gac cac gtc gat gtc gga aac gcc 2803 Ala Asp Glu Val Arg Thr Trp Leu Asp His Val Asp Val Gly Asn Ala 890 895 900 tac gtc aac cgc ggc atc acc ggc gcc att gtc caa cgc caa tcc ttc 2851 Tyr Val Asn Arg Gly Ile Thr Gly Ala Ile Val Gln Arg Gln Ser Phe 905 910 915 gga ggc tgg aaa aaa tcc tcc gtc ggc ctc gga tcc aaa gcc gga gga 2899 Gly Gly Trp Lys Lys Ser Ser Val Gly Leu Gly Ser Lys Ala Gly Gly 920 925 930 ccc aac tat gtc atg ctc atg gga acc tgg gcc gac gcg cca agc cac 2947 Pro Asn Tyr Val Met Leu Met Gly Thr Trp Ala Asp Ala Pro Ser His 935 940 945 cac gcc cca cgc gaa aca aac ccg ctg atc agc aaa ctg gat ctc ccc 2995 His Ala Pro Arg Glu Thr Asn Pro Leu Ile Ser Lys Leu Asp Leu Pro 950 955 960 965 gga gaa gag ctc gaa tgg ctc gaa aaa gcc aac gcc agc gat gaa aca 3043 Gly Glu Glu Leu Glu Trp Leu Glu Lys Ala Asn Ala Ser Asp Glu Thr 970 975 980 gca tgg aac acg gaa ttc ggc agc cca cgc gac ccc tcc ggc ctc gat 3091 Ala Trp Asn Thr Glu Phe Gly Ser Pro Arg Asp Pro Ser Gly Leu Asp 985 990 995 gta gaa gcc aac att ttc cgc tac cga cca gca 3124 Val Glu Ala Asn Ile Phe Arg Tyr Arg Pro Ala 1000 1005 <210> 312 <211> 1008 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 181, 182 <223> Xaa = any amino acid <220> <221> VARIANT <222> 183 <223> Xaa = Phe, Ser, Tyr, or Cys <400> 312 Met Thr Ser Met Asn Leu Pro Ile Glu Leu Ala Thr Leu Ser Asp Gln 1 5 10 15 Ala Val Asp Lys Val Arg Ser Trp Leu Glu Tyr Ser Lys Lys Glu Ser 20 25 30 Val Pro Asn Ala Asp Ala Lys Arg Leu Ala Ala Val Leu Gln Asp Pro 35 40 45 Asn Gly Leu Glu Phe Thr Val Gly Phe Val Asp Arg Val Val Arg Thr 50 55 60 Glu Asp Arg Glu Ala Ala Ala His Ala Leu Tyr Glu Leu Gly Lys Ile 65 70 75 80 Ala Pro Ser Thr Met Ser Phe Leu Asp Arg Ala Gln Ile Gln Ala Gly 85 90 95 Ser Leu Val Gly Arg Ala Leu Pro Gln Val Val Val Pro Ala Ala Arg 100 105 110 Ala Arg Ile Arg Gln Met Val Gly His Met Ile Val Asp Ala Arg Asp 115 120 125 Lys Gln Phe Ala Lys Ala Val Ala Glu Ile Gln Ser Asp Gly His Arg 130 135 140 Leu Asn Ile Asn Leu Leu Gly Glu Ala Val Leu Gly Arg Lys Glu Ala 145 150 155 160 Ala Lys His Leu Asp Asp Thr Val Arg Leu Leu Arg Arg Pro Asp Val 165 170 175 Glu Tyr Val Ser Xaa Xaa Xaa Ser Ser Val Ala Ser Gln Ile Ser Met 180 185 190 Trp Gly Phe Glu Asp Thr Val Asn Tyr Val Val Glu Gln Leu Thr Pro 195 200 205 Leu Tyr Ile Glu Pro Ala Arg Ala Pro Lys Gly Thr Lys Phe Ile Asn 210 215 220 Leu Asp Met Glu Glu Tyr Arg Asp Leu Arg Leu Thr Met Glu Val Phe 225 230 235 240 Lys Arg Leu Leu Ser Asn Pro Glu Leu His Glu Leu Glu Ala Gly Ile 245 250 255 Val Leu Gln Ala Tyr Leu Pro Asp Ala Leu Gly Ala Ile Gln Asp Leu 260 265 270 Ala Gln Phe Gly Arg Glu Arg Val Asn Thr Gly Gly Ala Gly Val Lys 275 280 285 Val Arg Leu Val Lys Gly Ala Asn Leu Pro Met Glu His Val His Ala 290 295 300 Gln Ile Thr Gly Trp Pro Val Ala Thr Glu Pro Ser Lys Gln Ala Thr 305 310 315 320 Asp Ala Asn Tyr Lys Arg Val Leu Tyr Trp Thr Met Arg Lys Glu Asn 325 330 335 Met Glu Gly Leu Arg Leu Gly Val Ala Gly His Asn Leu Phe Asp Ile 340 345 350 Ala Phe Ala His Leu Leu Ser Val Glu Arg Gly Val Ala Asp Arg Val 355 360 365 Glu Phe Glu Met Leu Gln Gly Met Ala Ser Asp Gln Ala Arg Ala Val 370 375 380 Ser Val Asp Val Gly Glu Leu Leu Leu Tyr Val Pro Ala Val Arg Pro 385 390 395 400 Gln Glu Phe Asp Val Ala Ile Ser Tyr Leu Val Arg Arg Leu Glu Glu 405 410 415 Asn Ala Ala Ser Glu Asn Phe Met Ser Ala Ile Phe Asp Leu Asp Ala 420 425 430 Asp Asn Pro Ser Phe Lys Arg Glu Glu Ser Arg Phe Arg Ala Ser Ile 435 440 445 Ser Asp Leu Ala Thr Leu Ile Asp Val Pro Ala Pro Gly Pro Asn His 450 455 460 Thr Gln Asp Arg Ser Lys Glu Thr Leu Leu Asp Ala Pro Leu Val Pro 465 470 475 480 Phe Ile Asn Glu Pro Asp Thr Asn Pro Ala Leu Ile Gln Asn Gln Gln 485 490 495 Trp Ala Thr Lys Ala Val Ala Thr Ala Ala Glu Pro Gly Trp Leu Glu 500 505 510 Lys Gln Thr Lys Pro Glu Val Leu Glu Glu Gly Asp Val Asp Lys Leu 515 520 525 Ile Asn Asp Val Arg Asp Ala Ala Glu Ala Trp Ala Ala Arg Pro Ala 530 535 540 Arg Glu Arg Ala Glu Ile Leu Tyr Lys Thr Ala Glu Ile Leu Arg Val 545 550 555 560 Arg Arg Gly His Leu Ile Ser Val Thr Ala Ala Glu Val Gly Lys Ala 565 570 575 Val Glu Gln Thr Asp Pro Glu Ile Ser Glu Ala Ile Asp Phe Ala Arg 580 585 590 Tyr Tyr Ala His Leu Ala Leu Glu Leu Asp Asp Val Asp Asn Ala Glu 595 600 605 Phe Thr Pro Asp Arg Val Val Val Val Thr Pro Pro Trp Asn Phe Pro 610 615 620 Ile Ala Ile Pro Ala Gly Ser Thr Phe Ala Ala Leu Ala Ala Gly Ala 625 630 635 640 Gly Val Ile His Lys Pro Ser Lys Pro Ser Gln His Cys Ser Ala Ala 645 650 655 Val Val Glu Ala Leu Trp Glu Ala Gly Val Pro Arg Glu Val Leu His 660 665 670 Cys Ile Tyr Pro Ala Asn Arg Asp Val Gly Cys Ala Leu Ile Ser His 675 680 685 Glu His Val Asp Arg Val Ile Leu Thr Gly Ser Ser Glu Thr Ala Ala 690 695 700 Met Phe Ser Ser Trp Arg Pro Glu Leu Thr Ile Asn Gly Glu Thr Ser 705 710 715 720 Gly Lys Asn Ala Ile Val Val Thr Pro Ser Ala Asp Arg Asp Leu Ala 725 730 735 Val Ala Asp Leu Val Lys Ser Ala Phe Gly His Ala Gly Gln Lys Cys 740 745 750 Ser Ala Ala Ser Leu Gly Ile Leu Val Gly Ser Val Tyr Glu Ser Glu 755 760 765 Arg Phe Arg Lys Gln Leu Val Asp Ala Ala Ser Ser Leu Ile Val Asp 770 775 780 Trp Pro Thr Asn Pro Ser Ala Thr Val Gly Pro Leu Thr Glu Leu Pro 785 790 795 800 Ser Asp Lys Leu His His Ala Leu Thr Thr Leu Glu Glu Gly Glu Ser 805 810 815 Trp Leu Leu Lys Pro Arg Gln Leu Asp Asp Thr Gly Arg Leu Trp Ser 820 825 830 Pro Gly Ile Lys Glu Gly Val Lys Pro Gly Thr Phe Phe His Leu Thr 835 840 845 Glu Val Phe Gly Pro Val Leu Gly Leu Met Lys Ala Thr Asp Leu Asn 850 855 860 Glu Ala Ile Glu Phe Gln Asn Gly Asn Asp Phe Gly Leu Thr Gly Gly 865 870 875 880 Leu Gln Ser Leu Asp Ala Asp Glu Val Arg Thr Trp Leu Asp His Val 885 890 895 Asp Val Gly Asn Ala Tyr Val Asn Arg Gly Ile Thr Gly Ala Ile Val 900 905 910 Gln Arg Gln Ser Phe Gly Gly Trp Lys Lys Ser Ser Val Gly Leu Gly 915 920 925 Ser Lys Ala Gly Gly Pro Asn Tyr Val Met Leu Met Gly Thr Trp Ala 930 935 940 Asp Ala Pro Ser His His Ala Pro Arg Glu Thr Asn Pro Leu Ile Ser 945 950 955 960 Lys Leu Asp Leu Pro Gly Glu Glu Leu Glu Trp Leu Glu Lys Ala Asn 965 970 975 Ala Ser Asp Glu Thr Ala Trp Asn Thr Glu Phe Gly Ser Pro Arg Asp 980 985 990 Pro Ser Gly Leu Asp Val Glu Ala Asn Ile Phe Arg Tyr Arg Pro Ala 995 1000 1005 <210> 313 <211> 927 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(904) <223> RXC02498 <400> 313 caaggtagaa atttgtccgt gggcacttcg tgaaggtgtg atcctcacca ggatcgacaa 60 aggactcgag taacatttac ccggaaagga gttggcgaaa atg agt gaa gag aaa 115 Met Ser Glu Glu Lys 1 5 ctc aca gtc gct gag ctg atg gcg cgt gcc gcg aaa gag gga cgc tcc 163 Leu Thr Val Ala Glu Leu Met Ala Arg Ala Ala Lys Glu Gly Arg Ser 10 15 20 acc gat gct ccc cga cga cgc agg cgc cgc agc atc gaa gac ggt ggc 211 Thr Asp Ala Pro Arg Arg Arg Arg Arg Arg Ser Ile Glu Asp Gly Gly 25 30 35 gta tcc gtt gct gag ctg acc ggc tcc att cct gcc gtt aag gaa aag 259 Val Ser Val Ala Glu Leu Thr Gly Ser Ile Pro Ala Val Lys Glu Lys 40 45 50 ccc gcg gag tcc aag cac tcc agc gtg ccc atc gat gca cca gca gaa 307 Pro Ala Glu Ser Lys His Ser Ser Val Pro Ile Asp Ala Pro Ala Glu 55 60 65 cct gag gtt gtt gag gcc ccc aag cct gag ccc gcc gaa gaa gta gaa 355 Pro Glu Val Val Glu Ala Pro Lys Pro Glu Pro Ala Glu Glu Val Glu 70 75 80 85 gtg gct tcg gtg gag ggc gac gtc gat aag cag gaa acc cct gag cgt 403 Val Ala Ser Val Glu Gly Asp Val Asp Lys Gln Glu Thr Pro Glu Arg 90 95 100 ccg gcg ccg agc aac gaa gaa acc atg gtg ctg cgc atc gtg gat gaa 451 Pro Ala Pro Ser Asn Glu Glu Thr Met Val Leu Arg Ile Val Asp Glu 105 110 115 aaa gat cca att agc ttg acg acg ggc gcg ttc ccc gtg gtt ccg gca 499 Lys Asp Pro Ile Ser Leu Thr Thr Gly Ala Phe Pro Val Val Pro Ala 120 125 130 gtt gcc gcc aag ccg gcg ccc gta gtg cgc gcg gag aag gac gcc gat 547 Val Ala Ala Lys Pro Ala Pro Val Val Arg Ala Glu Lys Asp Ala Asp 135 140 145 gtg gag act gcc gta aag gca gat ttc gca gag gtg gaa gtc gat aac 595 Val Glu Thr Ala Val Lys Ala Asp Phe Ala Glu Val Glu Val Asp Asn 150 155 160 165 act gac acc acg cag atg gct gtg gtg gaa gaa gtt gac gag gag cca 643 Thr Asp Thr Thr Gln Met Ala Val Val Glu Glu Val Asp Glu Glu Pro 170 175 180 gag caa gaa aac aaa atg tcc gta ttc gcg atc atc atg atg gcg atc 691 Glu Gln Glu Asn Lys Met Ser Val Phe Ala Ile Ile Met Met Ala Ile 185 190 195 gtc gga gtt gtt ctc ggt gtc gtt gta ttc ctc ggc ttt gaa atg ctg 739 Val Gly Val Val Leu Gly Val Val Val Phe Leu Gly Phe Glu Met Leu 200 205 210 tgg gag cgc ctg aac aag tgg atc gtc gct gtt ctg gca gtc ggc gtg 787 Trp Glu Arg Leu Asn Lys Trp Ile Val Ala Val Leu Ala Val Gly Val 215 220 225 acc ttg gga atg gtg ggc atc atc cac gct ttg cgc acc tca cgt gat 835 Thr Leu Gly Met Val Gly Ile Ile His Ala Leu Arg Thr Ser Arg Asp 230 235 240 245 ggt ttc agc atg gtt ctc gca gga atc gtg ggc ctg gtc atg acg ttc 883 Gly Phe Ser Met Val Leu Ala Gly Ile Val Gly Leu Val Met Thr Phe 250 255 260 ggg ccg ctg gca atc gtc atg taatttgtcg ttttgggccc ccg 927 Gly Pro Leu Ala Ile Val Met 265 <210> 314 <211> 268 <212> PRT <213> Corynebacterium glutamicum <400> 314 Met Ser Glu Glu Lys Leu Thr Val Ala Glu Leu Met Ala Arg Ala Ala 1 5 10 15 Lys Glu Gly Arg Ser Thr Asp Ala Pro Arg Arg Arg Arg Arg Arg Ser 20 25 30 Ile Glu Asp Gly Gly Val Ser Val Ala Glu Leu Thr Gly Ser Ile Pro 35 40 45 Ala Val Lys Glu Lys Pro Ala Glu Ser Lys His Ser Ser Val Pro Ile 50 55 60 Asp Ala Pro Ala Glu Pro Glu Val Val Glu Ala Pro Lys Pro Glu Pro 65 70 75 80 Ala Glu Glu Val Glu Val Ala Ser Val Glu Gly Asp Val Asp Lys Gln 85 90 95 Glu Thr Pro Glu Arg Pro Ala Pro Ser Asn Glu Glu Thr Met Val Leu 100 105 110 Arg Ile Val Asp Glu Lys Asp Pro Ile Ser Leu Thr Thr Gly Ala Phe 115 120 125 Pro Val Val Pro Ala Val Ala Ala Lys Pro Ala Pro Val Val Arg Ala 130 135 140 Glu Lys Asp Ala Asp Val Glu Thr Ala Val Lys Ala Asp Phe Ala Glu 145 150 155 160 Val Glu Val Asp Asn Thr Asp Thr Thr Gln Met Ala Val Val Glu Glu 165 170 175 Val Asp Glu Glu Pro Glu Gln Glu Asn Lys Met Ser Val Phe Ala Ile 180 185 190 Ile Met Met Ala Ile Val Gly Val Val Leu Gly Val Val Val Phe Leu 195 200 205 Gly Phe Glu Met Leu Trp Glu Arg Leu Asn Lys Trp Ile Val Ala Val 210 215 220 Leu Ala Val Gly Val Thr Leu Gly Met Val Gly Ile Ile His Ala Leu 225 230 235 240 Arg Thr Ser Arg Asp Gly Phe Ser Met Val Leu Ala Gly Ile Val Gly 245 250 255 Leu Val Met Thr Phe Gly Pro Leu Ala Ile Val Met 260 265 <210> 315 <211> 774 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(751) <223> RXA01491 <400> 315 aacggtgtga aacacattga agtgtcgttg ggttatccgc gcgaatggga gcattggtct 60 gggcagcatg tgtggccata tccagtgatg gaggtggaca atg ctg gat gag tct 115 Met Leu Asp Glu Ser 1 5 ttg ttt cca aat tcg gca aag ttt tct ttc att aaa act ggc gat gct 163 Leu Phe Pro Asn Ser Ala Lys Phe Ser Phe Ile Lys Thr Gly Asp Ala 10 15 20 gtt aat tta gac cat ttc cat cag ttg cat ccg ttg gaa aag gca ctg 211 Val Asn Leu Asp His Phe His Gln Leu His Pro Leu Glu Lys Ala Leu 25 30 35 gta gcg cac tcg gtt gat att aga aaa gca gag ttt gga gat gcc agg 259 Val Ala His Ser Val Asp Ile Arg Lys Ala Glu Phe Gly Asp Ala Arg 40 45 50 tgg tgt gca cat cag gca ctc caa gct ttg gga cga gat agc ggt gat 307 Trp Cys Ala His Gln Ala Leu Gln Ala Leu Gly Arg Asp Ser Gly Asp 55 60 65 ccc att ttg cgt ggg gaa cga gga atg cca ttg tgg cct tct tcg gtg 355 Pro Ile Leu Arg Gly Glu Arg Gly Met Pro Leu Trp Pro Ser Ser Val 70 75 80 85 tct ggt tca ttg acc cac act gac gga ttc cga gct gct gtt gtg gcg 403 Ser Gly Ser Leu Thr His Thr Asp Gly Phe Arg Ala Ala Val Val Ala 90 95 100 cca cga ttg ttg gtg cgt tct atg gga ttg gat gcc gaa cct gcg gag 451 Pro Arg Leu Leu Val Arg Ser Met Gly Leu Asp Ala Glu Pro Ala Glu 105 110 115 ccg ttg ccc aag gat gtt ttg ggt tca atc gct cgg gtg ggg gag att 499 Pro Leu Pro Lys Asp Val Leu Gly Ser Ile Ala Arg Val Gly Glu Ile 120 125 130 cct caa ctt aag cgc ttg gag gaa caa ggt gtg cac tgc gcg gat cgc 547 Pro Gln Leu Lys Arg Leu Glu Glu Gln Gly Val His Cys Ala Asp Arg 135 140 145 ctg ctg ttt tgt gcc aag gaa gca aca tac aaa gcg tgg ttc ccg ctg 595 Leu Leu Phe Cys Ala Lys Glu Ala Thr Tyr Lys Ala Trp Phe Pro Leu 150 155 160 165 acg cat agg tgg ctt ggt ttt gaa caa gct gag atc gac ttg cgt gat 643 Thr His Arg Trp Leu Gly Phe Glu Gln Ala Glu Ile Asp Leu Arg Asp 170 175 180 gat ggc act ttt gtg tcc tat ttg ctg gtt cga cca act cca gtg ccg 691 Asp Gly Thr Phe Val Ser Tyr Leu Leu Val Arg Pro Thr Pro Val Pro 185 190 195 ttt att tca ggt aaa tgg gta ctg cgt gat ggt tat gtc ata gct gcg 739 Phe Ile Ser Gly Lys Trp Val Leu Arg Asp Gly Tyr Val Ile Ala Ala 200 205 210 act gca gtg act tgaactggat ggagaggata cct 774 Thr Ala Val Thr 215 <210> 316 <211> 217 <212> PRT <213> Corynebacterium glutamicum <400> 316 Met Leu Asp Glu Ser Leu Phe Pro Asn Ser Ala Lys Phe Ser Phe Ile 1 5 10 15 Lys Thr Gly Asp Ala Val Asn Leu Asp His Phe His Gln Leu His Pro 20 25 30 Leu Glu Lys Ala Leu Val Ala His Ser Val Asp Ile Arg Lys Ala Glu 35 40 45 Phe Gly Asp Ala Arg Trp Cys Ala His Gln Ala Leu Gln Ala Leu Gly 50 55 60 Arg Asp Ser Gly Asp Pro Ile Leu Arg Gly Glu Arg Gly Met Pro Leu 65 70 75 80 Trp Pro Ser Ser Val Ser Gly Ser Leu Thr His Thr Asp Gly Phe Arg 85 90 95 Ala Ala Val Val Ala Pro Arg Leu Leu Val Arg Ser Met Gly Leu Asp 100 105 110 Ala Glu Pro Ala Glu Pro Leu Pro Lys Asp Val Leu Gly Ser Ile Ala 115 120 125 Arg Val Gly Glu Ile Pro Gln Leu Lys Arg Leu Glu Glu Gln Gly Val 130 135 140 His Cys Ala Asp Arg Leu Leu Phe Cys Ala Lys Glu Ala Thr Tyr Lys 145 150 155 160 Ala Trp Phe Pro Leu Thr His Arg Trp Leu Gly Phe Glu Gln Ala Glu 165 170 175 Ile Asp Leu Arg Asp Asp Gly Thr Phe Val Ser Tyr Leu Leu Val Arg 180 185 190 Pro Thr Pro Val Pro Phe Ile Ser Gly Lys Trp Val Leu Arg Asp Gly 195 200 205 Tyr Val Ile Ala Ala Thr Ala Val Thr 210 215 <210> 317 <211> 1287 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1264) <223> RXA02155 <400> 317 tcggcgtcgc accttaaagt agcgccttaa agcggcgctt caaaccaagc gccctaacca 60 gcaaacacaa caaacacatc taattcagta ggagttccac atg gca gaa aaa ggc 115 Met Ala Glu Lys Gly 1 5 att acc gcg ccg aaa ggc ttc gtt gct tct gca acg acc gcg ggt att 163 Ile Thr Ala Pro Lys Gly Phe Val Ala Ser Ala Thr Thr Ala Gly Ile 10 15 20 aaa gct tct ggc aat cct gac atg gcg ttg gtg gtt aac cag ggt cca 211 Lys Ala Ser Gly Asn Pro Asp Met Ala Leu Val Val Asn Gln Gly Pro 25 30 35 gag ttt tcc gca gcg gcc gtg ttt aca cgt aac cga gtt ttc gca gcg 259 Glu Phe Ser Ala Ala Ala Val Phe Thr Arg Asn Arg Val Phe Ala Ala 40 45 50 cct gtg aag gtg agc cga gag aac gtt gct gat ggc cag atc agg gct 307 Pro Val Lys Val Ser Arg Glu Asn Val Ala Asp Gly Gln Ile Arg Ala 55 60 65 gtt ttg tac aac gct ggt aat gct aat gcg tgt aat ggt ctg cag ggt 355 Val Leu Tyr Asn Ala Gly Asn Ala Asn Ala Cys Asn Gly Leu Gln Gly 70 75 80 85 gag aag gat gct cgt gag tct gtt tct cat cta gct caa aat ttg ggc 403 Glu Lys Asp Ala Arg Glu Ser Val Ser His Leu Ala Gln Asn Leu Gly 90 95 100 ttg gag gat tcc gat att ggt gtg tgt tcc act ggt ctt att ggt gag 451 Leu Glu Asp Ser Asp Ile Gly Val Cys Ser Thr Gly Leu Ile Gly Glu 105 110 115 ttg ctt ccg atg gat aag ctc aat gca ggt att gat cag ctg acc gct 499 Leu Leu Pro Met Asp Lys Leu Asn Ala Gly Ile Asp Gln Leu Thr Ala 120 125 130 gag ggc gct ttg ggt gac aat ggt gca gct gct gcc aag gcg atc atg 547 Glu Gly Ala Leu Gly Asp Asn Gly Ala Ala Ala Ala Lys Ala Ile Met 135 140 145 acc act gac acg gtg gat aag gaa acc gtc gtg ttt gct gat ggt tgg 595 Thr Thr Asp Thr Val Asp Lys Glu Thr Val Val Phe Ala Asp Gly Trp 150 155 160 165 act gtc ggc gga atg ggc aag ggc gtg ggc atg atg gcg ccg tct ctt 643 Thr Val Gly Gly Met Gly Lys Gly Val Gly Met Met Ala Pro Ser Leu 170 175 180 gcc acc atg ctg gtc tgc ttg acc act gat gca tcc gtt act cag gaa 691 Ala Thr Met Leu Val Cys Leu Thr Thr Asp Ala Ser Val Thr Gln Glu 185 190 195 atg gct cag atc gcg ctg gct aat gct acg gcc gtt acg ttt gac acc 739 Met Ala Gln Ile Ala Leu Ala Asn Ala Thr Ala Val Thr Phe Asp Thr 200 205 210 ctg gat att gat gga tca acc tcc acc aat gac acc gtg ttc ctg ctg 787 Leu Asp Ile Asp Gly Ser Thr Ser Thr Asn Asp Thr Val Phe Leu Leu 215 220 225 gca tct ggc gct agc gga atc acc cca act cag gat gaa ctc aac gat 835 Ala Ser Gly Ala Ser Gly Ile Thr Pro Thr Gln Asp Glu Leu Asn Asp 230 235 240 245 gcg gtg tac gca gct tgt tct gat atc gca gcg aag ctt cag gct gat 883 Ala Val Tyr Ala Ala Cys Ser Asp Ile Ala Ala Lys Leu Gln Ala Asp 250 255 260 gca gag ggt gtg acc aag cgc gtt gct gtg aca gtg gtg gga acc acc 931 Ala Glu Gly Val Thr Lys Arg Val Ala Val Thr Val Val Gly Thr Thr 265 270 275 aac aac gag cag gcg att aat gcg gct cgc act gtt gct cgt gac aat 979 Asn Asn Glu Gln Ala Ile Asn Ala Ala Arg Thr Val Ala Arg Asp Asn 280 285 290 ttg ttc aag tgc gca atg ttt gga tct gat cca aac tgg ggt cgc gtg 1027 Leu Phe Lys Cys Ala Met Phe Gly Ser Asp Pro Asn Trp Gly Arg Val 295 300 305 ttg gct gca gtc ggc atg gct gat gct gat atg gaa cca gag aag att 1075 Leu Ala Ala Val Gly Met Ala Asp Ala Asp Met Glu Pro Glu Lys Ile 310 315 320 325 tct gtg ttc ttc aat ggt caa gca gta tgc ctt gat tcc act ggc gct 1123 Ser Val Phe Phe Asn Gly Gln Ala Val Cys Leu Asp Ser Thr Gly Ala 330 335 340 cct ggt gct cgt gag gtg gat ctt tcc ggc gct gac att gat gtc cga 1171 Pro Gly Ala Arg Glu Val Asp Leu Ser Gly Ala Asp Ile Asp Val Arg 345 350 355 att gat ttg ggc acc agt ggg gaa ggc cag gca aca gtt cga acc act 1219 Ile Asp Leu Gly Thr Ser Gly Glu Gly Gln Ala Thr Val Arg Thr Thr 360 365 370 gac ctg agc ttc tcc tac gtg gag atc aac tcc gcg tac agc tct 1264 Asp Leu Ser Phe Ser Tyr Val Glu Ile Asn Ser Ala Tyr Ser Ser 375 380 385 taaaaagaaa cagcactcca act 1287 <210> 318 <211> 388 <212> PRT <213> Corynebacterium glutamicum <400> 318 Met Ala Glu Lys Gly Ile Thr Ala Pro Lys Gly Phe Val Ala Ser Ala 1 5 10 15 Thr Thr Ala Gly Ile Lys Ala Ser Gly Asn Pro Asp Met Ala Leu Val 20 25 30 Val Asn Gln Gly Pro Glu Phe Ser Ala Ala Ala Val Phe Thr Arg Asn 35 40 45 Arg Val Phe Ala Ala Pro Val Lys Val Ser Arg Glu Asn Val Ala Asp 50 55 60 Gly Gln Ile Arg Ala Val Leu Tyr Asn Ala Gly Asn Ala Asn Ala Cys 65 70 75 80 Asn Gly Leu Gln Gly Glu Lys Asp Ala Arg Glu Ser Val Ser His Leu 85 90 95 Ala Gln Asn Leu Gly Leu Glu Asp Ser Asp Ile Gly Val Cys Ser Thr 100 105 110 Gly Leu Ile Gly Glu Leu Leu Pro Met Asp Lys Leu Asn Ala Gly Ile 115 120 125 Asp Gln Leu Thr Ala Glu Gly Ala Leu Gly Asp Asn Gly Ala Ala Ala 130 135 140 Ala Lys Ala Ile Met Thr Thr Asp Thr Val Asp Lys Glu Thr Val Val 145 150 155 160 Phe Ala Asp Gly Trp Thr Val Gly Gly Met Gly Lys Gly Val Gly Met 165 170 175 Met Ala Pro Ser Leu Ala Thr Met Leu Val Cys Leu Thr Thr Asp Ala 180 185 190 Ser Val Thr Gln Glu Met Ala Gln Ile Ala Leu Ala Asn Ala Thr Ala 195 200 205 Val Thr Phe Asp Thr Leu Asp Ile Asp Gly Ser Thr Ser Thr Asn Asp 210 215 220 Thr Val Phe Leu Leu Ala Ser Gly Ala Ser Gly Ile Thr Pro Thr Gln 225 230 235 240 Asp Glu Leu Asn Asp Ala Val Tyr Ala Ala Cys Ser Asp Ile Ala Ala 245 250 255 Lys Leu Gln Ala Asp Ala Glu Gly Val Thr Lys Arg Val Ala Val Thr 260 265 270 Val Val Gly Thr Thr Asn Asn Glu Gln Ala Ile Asn Ala Ala Arg Thr 275 280 285 Val Ala Arg Asp Asn Leu Phe Lys Cys Ala Met Phe Gly Ser Asp Pro 290 295 300 Asn Trp Gly Arg Val Leu Ala Ala Val Gly Met Ala Asp Ala Asp Met 305 310 315 320 Glu Pro Glu Lys Ile Ser Val Phe Phe Asn Gly Gln Ala Val Cys Leu 325 330 335 Asp Ser Thr Gly Ala Pro Gly Ala Arg Glu Val Asp Leu Ser Gly Ala 340 345 350 Asp Ile Asp Val Arg Ile Asp Leu Gly Thr Ser Gly Glu Gly Gln Ala 355 360 365 Thr Val Arg Thr Thr Asp Leu Ser Phe Ser Tyr Val Glu Ile Asn Ser 370 375 380 Ala Tyr Ser Ser 385 <210> 319 <211> 1074 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1051) <223> RXA02156 <400> 319 aaccactgac ctgagcttct cctacgtgga gatcaactcc gcgtacagct cttaaaaaga 60 aacagcactc caactaacaa gcagggaaaa gggcacaggc atg aat gac ttg atc 115 Met Asn Asp Leu Ile 1 5 aaa gat tta ggc tct gag gtg cgc gca aat gtc ctc gct gag gcg ttg 163 Lys Asp Leu Gly Ser Glu Val Arg Ala Asn Val Leu Ala Glu Ala Leu 10 15 20 cca tgg ttg cag cac ttc cgc gac aag att gtt gtc gtg aaa tat ggc 211 Pro Trp Leu Gln His Phe Arg Asp Lys Ile Val Val Val Lys Tyr Gly 25 30 35 gga aac gcc atg gtg gat gat gat ctc aag gct gct ttt gct gcc gac 259 Gly Asn Ala Met Val Asp Asp Asp Leu Lys Ala Ala Phe Ala Ala Asp 40 45 50 atg gtc ttc ttg cgc acc gtg ggc gca aaa cca gtg gtg gtg cac ggt 307 Met Val Phe Leu Arg Thr Val Gly Ala Lys Pro Val Val Val His Gly 55 60 65 ggt gga cct cag att tct gag atg cta aac cgt gtg ggt ctc cag ggc 355 Gly Gly Pro Gln Ile Ser Glu Met Leu Asn Arg Val Gly Leu Gln Gly 70 75 80 85 gag ttc aag ggt ggt ttc cgt gtg acc act cct gag gtc atg gac att 403 Glu Phe Lys Gly Gly Phe Arg Val Thr Thr Pro Glu Val Met Asp Ile 90 95 100 gtg cgc atg gtg ctc ttt ggt cag gtc ggt cgc gat tta gtt ggt ttg 451 Val Arg Met Val Leu Phe Gly Gln Val Gly Arg Asp Leu Val Gly Leu 105 110 115 atc aac tct cat ggc cct tac gct gtg gga acc tcc ggt gag gat gcc 499 Ile Asn Ser His Gly Pro Tyr Ala Val Gly Thr Ser Gly Glu Asp Ala 120 125 130 ggc ctg ttt acc gcg cag aag cgc atg gtc aac atc gat ggc gta ccc 547 Gly Leu Phe Thr Ala Gln Lys Arg Met Val Asn Ile Asp Gly Val Pro 135 140 145 act gat att ggt ttg gtc gga gac atc att aat gtc gat gcc tct tcc 595 Thr Asp Ile Gly Leu Val Gly Asp Ile Ile Asn Val Asp Ala Ser Ser 150 155 160 165 ttg atg gat atc atc gag gcc ggt cgc att cct gtg gtc tct acg att 643 Leu Met Asp Ile Ile Glu Ala Gly Arg Ile Pro Val Val Ser Thr Ile 170 175 180 gct cca ggc gaa gac ggc cag att tac aac att aac gcc gat acc gca 691 Ala Pro Gly Glu Asp Gly Gln Ile Tyr Asn Ile Asn Ala Asp Thr Ala 185 190 195 gca ggt gct ttg gct gca gcg att ggt gca gaa cgc ctg ctg gtt ctc 739 Ala Gly Ala Leu Ala Ala Ala Ile Gly Ala Glu Arg Leu Leu Val Leu 200 205 210 acc aat gtg gaa ggt ctg tac acc gat tgg cct gat aag agc tca ctg 787 Thr Asn Val Glu Gly Leu Tyr Thr Asp Trp Pro Asp Lys Ser Ser Leu 215 220 225 gtg tcc aag atc aag gcc acc gag ctg gag gcc att ctt ccg gga ctt 835 Val Ser Lys Ile Lys Ala Thr Glu Leu Glu Ala Ile Leu Pro Gly Leu 230 235 240 245 gat tcc ggc atg att cca aag atg gag tct tgc ttg aac gcg gtg cgt 883 Asp Ser Gly Met Ile Pro Lys Met Glu Ser Cys Leu Asn Ala Val Arg 250 255 260 ggg gga gta agc gct gct cat gtc att gac ggc cgc atc gcg cac tcg 931 Gly Gly Val Ser Ala Ala His Val Ile Asp Gly Arg Ile Ala His Ser 265 270 275 gtg ttg ctg gag ctt ttg acc atg ggt gga att ggc acg atg gtg ctg 979 Val Leu Leu Glu Leu Leu Thr Met Gly Gly Ile Gly Thr Met Val Leu 280 285 290 ccg gat gtt ttt gat cgg gag aat tat cct gaa ggc acc gtt ttt aga 1027 Pro Asp Val Phe Asp Arg Glu Asn Tyr Pro Glu Gly Thr Val Phe Arg 295 300 305 aaa gac gac aag gat ggg gaa ctg taaatgagca cgctggaaac ttg 1074 Lys Asp Asp Lys Asp Gly Glu Leu 310 315 <210> 320 <211> 317 <212> PRT <213> Corynebacterium glutamicum <400> 320 Met Asn Asp Leu Ile Lys Asp Leu Gly Ser Glu Val Arg Ala Asn Val 1 5 10 15 Leu Ala Glu Ala Leu Pro Trp Leu Gln His Phe Arg Asp Lys Ile Val 20 25 30 Val Val Lys Tyr Gly Gly Asn Ala Met Val Asp Asp Asp Leu Lys Ala 35 40 45 Ala Phe Ala Ala Asp Met Val Phe Leu Arg Thr Val Gly Ala Lys Pro 50 55 60 Val Val Val His Gly Gly Gly Pro Gln Ile Ser Glu Met Leu Asn Arg 65 70 75 80 Val Gly Leu Gln Gly Glu Phe Lys Gly Gly Phe Arg Val Thr Thr Pro 85 90 95 Glu Val Met Asp Ile Val Arg Met Val Leu Phe Gly Gln Val Gly Arg 100 105 110 Asp Leu Val Gly Leu Ile Asn Ser His Gly Pro Tyr Ala Val Gly Thr 115 120 125 Ser Gly Glu Asp Ala Gly Leu Phe Thr Ala Gln Lys Arg Met Val Asn 130 135 140 Ile Asp Gly Val Pro Thr Asp Ile Gly Leu Val Gly Asp Ile Ile Asn 145 150 155 160 Val Asp Ala Ser Ser Leu Met Asp Ile Ile Glu Ala Gly Arg Ile Pro 165 170 175 Val Val Ser Thr Ile Ala Pro Gly Glu Asp Gly Gln Ile Tyr Asn Ile 180 185 190 Asn Ala Asp Thr Ala Ala Gly Ala Leu Ala Ala Ala Ile Gly Ala Glu 195 200 205 Arg Leu Leu Val Leu Thr Asn Val Glu Gly Leu Tyr Thr Asp Trp Pro 210 215 220 Asp Lys Ser Ser Leu Val Ser Lys Ile Lys Ala Thr Glu Leu Glu Ala 225 230 235 240 Ile Leu Pro Gly Leu Asp Ser Gly Met Ile Pro Lys Met Glu Ser Cys 245 250 255 Leu Asn Ala Val Arg Gly Gly Val Ser Ala Ala His Val Ile Asp Gly 260 265 270 Arg Ile Ala His Ser Val Leu Leu Glu Leu Leu Thr Met Gly Gly Ile 275 280 285 Gly Thr Met Val Leu Pro Asp Val Phe Asp Arg Glu Asn Tyr Pro Glu 290 295 300 Gly Thr Val Phe Arg Lys Asp Asp Lys Asp Gly Glu Leu 305 310 315 <210> 321 <211> 903 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(880) <223> RXN02153 <400> 321 cccacttgca gttttagctg taggtgggtt tttgcatgtc taacccgtct tttatgcaca 60 cccccgcaat gaatcaaaaa tttatgcatg aataatttgc atg atc atg cat aac 115 Met Ile Met His Asn 1 5 gtg tat ggt gta act atg aca atc aag gtt gca atc gca gga gcc agt 163 Val Tyr Gly Val Thr Met Thr Ile Lys Val Ala Ile Ala Gly Ala Ser 10 15 20 gga tat gcc ggc gga gaa atc ctt cgt ctc ctt tta ggc cat cca gct 211 Gly Tyr Ala Gly Gly Glu Ile Leu Arg Leu Leu Leu Gly His Pro Ala 25 30 35 tat gca tct ggt gaa cta gaa atc gga gca ctc acc gcg gca tca acc 259 Tyr Ala Ser Gly Glu Leu Glu Ile Gly Ala Leu Thr Ala Ala Ser Thr 40 45 50 gca ggc agc acg ctc ggt gaa ttg atg cca cac att ccg cag ttg gcg 307 Ala Gly Ser Thr Leu Gly Glu Leu Met Pro His Ile Pro Gln Leu Ala 55 60 65 gat cgt gtt att caa gac acc aca gct gaa act cta gcc ggt cat gat 355 Asp Arg Val Ile Gln Asp Thr Thr Ala Glu Thr Leu Ala Gly His Asp 70 75 80 85 gtc gta ttt cta gga ctt cca cac gga ttc tct gca gaa att gca ctt 403 Val Val Phe Leu Gly Leu Pro His Gly Phe Ser Ala Glu Ile Ala Leu 90 95 100 cag ctc gga cca gat gtc aca gtg att gac tgt gca gct gac ttt cgt 451 Gln Leu Gly Pro Asp Val Thr Val Ile Asp Cys Ala Ala Asp Phe Arg 105 110 115 ctg caa aat gct gca gat tgg gag aag ttc tac ggc tca gag cac cag 499 Leu Gln Asn Ala Ala Asp Trp Glu Lys Phe Tyr Gly Ser Glu His Gln 120 125 130 gga aca tgg cct tat ggc att cca gaa atg cca gga cac cgc gag gct 547 Gly Thr Trp Pro Tyr Gly Ile Pro Glu Met Pro Gly His Arg Glu Ala 135 140 145 ctt cgt ggt gct aag cgt gta gca gtg cca gga tgt ttc cca acc ggt 595 Leu Arg Gly Ala Lys Arg Val Ala Val Pro Gly Cys Phe Pro Thr Gly 150 155 160 165 gca acc ttg gct ctt ctt cct gcg gtt caa gcg gga ctt atc gag cca 643 Ala Thr Leu Ala Leu Leu Pro Ala Val Gln Ala Gly Leu Ile Glu Pro 170 175 180 gat gtt tcc gta gtg tcc atc acc ggc gta tca ggt gca ggt aag aaa 691 Asp Val Ser Val Val Ser Ile Thr Gly Val Ser Gly Ala Gly Lys Lys 185 190 195 gca tct gtt gca cta ctt ggc tcg gaa acc atg ggt tca ctc aag gcg 739 Ala Ser Val Ala Leu Leu Gly Ser Glu Thr Met Gly Ser Leu Lys Ala 200 205 210 tac aac acc tcc gga aag cac cgc cac acc ccg gaa att gcc cag aac 787 Tyr Asn Thr Ser Gly Lys His Arg His Thr Pro Glu Ile Ala Gln Asn 215 220 225 ctc ggc gaa gtc agc gac aag cca gtc aag gtg agc ttc acc cca gtg 835 Leu Gly Glu Val Ser Asp Lys Pro Val Lys Val Ser Phe Thr Pro Val 230 235 240 245 ctt gca ccg tta cct cgc gaa ttc tca cca ctg caa ccg cac ctt 880 Leu Ala Pro Leu Pro Arg Glu Phe Ser Pro Leu Gln Pro His Leu 250 255 260 tgaaagaagg cgttaccgca gaa 903 <210> 322 <211> 260 <212> PRT <213> Corynebacterium glutamicum <400> 322 Met Ile Met His Asn Val Tyr Gly Val Thr Met Thr Ile Lys Val Ala 1 5 10 15 Ile Ala Gly Ala Ser Gly Tyr Ala Gly Gly Glu Ile Leu Arg Leu Leu 20 25 30 Leu Gly His Pro Ala Tyr Ala Ser Gly Glu Leu Glu Ile Gly Ala Leu 35 40 45 Thr Ala Ala Ser Thr Ala Gly Ser Thr Leu Gly Glu Leu Met Pro His 50 55 60 Ile Pro Gln Leu Ala Asp Arg Val Ile Gln Asp Thr Thr Ala Glu Thr 65 70 75 80 Leu Ala Gly His Asp Val Val Phe Leu Gly Leu Pro His Gly Phe Ser 85 90 95 Ala Glu Ile Ala Leu Gln Leu Gly Pro Asp Val Thr Val Ile Asp Cys 100 105 110 Ala Ala Asp Phe Arg Leu Gln Asn Ala Ala Asp Trp Glu Lys Phe Tyr 115 120 125 Gly Ser Glu His Gln Gly Thr Trp Pro Tyr Gly Ile Pro Glu Met Pro 130 135 140 Gly His Arg Glu Ala Leu Arg Gly Ala Lys Arg Val Ala Val Pro Gly 145 150 155 160 Cys Phe Pro Thr Gly Ala Thr Leu Ala Leu Leu Pro Ala Val Gln Ala 165 170 175 Gly Leu Ile Glu Pro Asp Val Ser Val Val Ser Ile Thr Gly Val Ser 180 185 190 Gly Ala Gly Lys Lys Ala Ser Val Ala Leu Leu Gly Ser Glu Thr Met 195 200 205 Gly Ser Leu Lys Ala Tyr Asn Thr Ser Gly Lys His Arg His Thr Pro 210 215 220 Glu Ile Ala Gln Asn Leu Gly Glu Val Ser Asp Lys Pro Val Lys Val 225 230 235 240 Ser Phe Thr Pro Val Leu Ala Pro Leu Pro Arg Glu Phe Ser Pro Leu 245 250 255 Gln Pro His Leu 260 <210> 323 <211> 903 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(880) <223> FRXA02153 <400> 323 cccacttgca gttttagctg taggtgggtt tttgcatgtc taacccgtct tttatgcaca 60 cccccgcaat gaatcaaaaa tttatgcatg aataatttgc atg atc atg cat aac 115 Met Ile Met His Asn 1 5 gtg tat ggt gta act atg aca atc aag gtt gca atc gca gga gcc agt 163 Val Tyr Gly Val Thr Met Thr Ile Lys Val Ala Ile Ala Gly Ala Ser 10 15 20 gga tat gcc ggc gga gaa atc ctt cgt ctc ctt tta ggc cat cca gct 211 Gly Tyr Ala Gly Gly Glu Ile Leu Arg Leu Leu Leu Gly His Pro Ala 25 30 35 tat gca tct ggt gaa cta gaa atc gga gca ctc acc gcg gca tca acc 259 Tyr Ala Ser Gly Glu Leu Glu Ile Gly Ala Leu Thr Ala Ala Ser Thr 40 45 50 gca ggc agc acg ctc ggt gaa ttg atg cca cac att ccg cag ttg gcg 307 Ala Gly Ser Thr Leu Gly Glu Leu Met Pro His Ile Pro Gln Leu Ala 55 60 65 gat cgt gtt att caa gac acc aca gct gaa act cta gcc ggt cat gat 355 Asp Arg Val Ile Gln Asp Thr Thr Ala Glu Thr Leu Ala Gly His Asp 70 75 80 85 gtc gta ttt cta gga ctt cca cac gga ttc tct gca gaa att gca ctt 403 Val Val Phe Leu Gly Leu Pro His Gly Phe Ser Ala Glu Ile Ala Leu 90 95 100 cag ctc gga cca gat gtc aca gtg att gac tgt gca gct gac ttt cgt 451 Gln Leu Gly Pro Asp Val Thr Val Ile Asp Cys Ala Ala Asp Phe Arg 105 110 115 ctg caa aat gct gca gat tgg gag aag ttc tac ggc tca gag cac cag 499 Leu Gln Asn Ala Ala Asp Trp Glu Lys Phe Tyr Gly Ser Glu His Gln 120 125 130 gga aca tgg cct tat ggc att cca gaa atg cca gga cac cgc gag gct 547 Gly Thr Trp Pro Tyr Gly Ile Pro Glu Met Pro Gly His Arg Glu Ala 135 140 145 ctt cgt ggt gct aag cgt gta gca gtg cca gga tgt ttc cca acc ggt 595 Leu Arg Gly Ala Lys Arg Val Ala Val Pro Gly Cys Phe Pro Thr Gly 150 155 160 165 gca acc ttg gct ctt ctt cct gcg gtt caa gcg gga ctt atc gag cca 643 Ala Thr Leu Ala Leu Leu Pro Ala Val Gln Ala Gly Leu Ile Glu Pro 170 175 180 gat gtt tcc gta gtg tcc atc acc ggc gta tca ggt gca ggt aag aaa 691 Asp Val Ser Val Val Ser Ile Thr Gly Val Ser Gly Ala Gly Lys Lys 185 190 195 gca tct gtt gca cta ctt ggc tcg gaa acc atg ggt tca ctc aag gcg 739 Ala Ser Val Ala Leu Leu Gly Ser Glu Thr Met Gly Ser Leu Lys Ala 200 205 210 tac aac acc tcc gga aag cac cgc cac acc ccg gaa att gcc cag aac 787 Tyr Asn Thr Ser Gly Lys His Arg His Thr Pro Glu Ile Ala Gln Asn 215 220 225 ctc ggc gaa gtc agc gac aag cca gtc aag gtg agc ttc acc cca gtg 835 Leu Gly Glu Val Ser Asp Lys Pro Val Lys Val Ser Phe Thr Pro Val 230 235 240 245 ctt gca ccg tta cct cgc gaa ttc tca cca ctg caa ccg cac ctt 880 Leu Ala Pro Leu Pro Arg Glu Phe Ser Pro Leu Gln Pro His Leu 250 255 260 tgaaagaagg cgttaccgca gaa 903 <210> 324 <211> 260 <212> PRT <213> Corynebacterium glutamicum <400> 324 Met Ile Met His Asn Val Tyr Gly Val Thr Met Thr Ile Lys Val Ala 1 5 10 15 Ile Ala Gly Ala Ser Gly Tyr Ala Gly Gly Glu Ile Leu Arg Leu Leu 20 25 30 Leu Gly His Pro Ala Tyr Ala Ser Gly Glu Leu Glu Ile Gly Ala Leu 35 40 45 Thr Ala Ala Ser Thr Ala Gly Ser Thr Leu Gly Glu Leu Met Pro His 50 55 60 Ile Pro Gln Leu Ala Asp Arg Val Ile Gln Asp Thr Thr Ala Glu Thr 65 70 75 80 Leu Ala Gly His Asp Val Val Phe Leu Gly Leu Pro His Gly Phe Ser 85 90 95 Ala Glu Ile Ala Leu Gln Leu Gly Pro Asp Val Thr Val Ile Asp Cys 100 105 110 Ala Ala Asp Phe Arg Leu Gln Asn Ala Ala Asp Trp Glu Lys Phe Tyr 115 120 125 Gly Ser Glu His Gln Gly Thr Trp Pro Tyr Gly Ile Pro Glu Met Pro 130 135 140 Gly His Arg Glu Ala Leu Arg Gly Ala Lys Arg Val Ala Val Pro Gly 145 150 155 160 Cys Phe Pro Thr Gly Ala Thr Leu Ala Leu Leu Pro Ala Val Gln Ala 165 170 175 Gly Leu Ile Glu Pro Asp Val Ser Val Val Ser Ile Thr Gly Val Ser 180 185 190 Gly Ala Gly Lys Lys Ala Ser Val Ala Leu Leu Gly Ser Glu Thr Met 195 200 205 Gly Ser Leu Lys Ala Tyr Asn Thr Ser Gly Lys His Arg His Thr Pro 210 215 220 Glu Ile Ala Gln Asn Leu Gly Glu Val Ser Asp Lys Pro Val Lys Val 225 230 235 240 Ser Phe Thr Pro Val Leu Ala Pro Leu Pro Arg Glu Phe Ser Pro Leu 245 250 255 Gln Pro His Leu 260 <210> 325 <211> 414 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(391) <223> RXA02154 <400> 325 cccagaacct cggcgaagtc agcgacaagc cagtcaaggt gagcttcacc ccagtgcttg 60 caccgttacc tcgcgaattc tcaccactgc aaccgcacct ttg aaa gaa ggc gtt 115 Leu Lys Glu Gly Val 1 5 acc gca gaa cag gct cgc gca gta tat gaa gag ttc tat gca cag gaa 163 Thr Ala Glu Gln Ala Arg Ala Val Tyr Glu Glu Phe Tyr Ala Gln Glu 10 15 20 acc ttc gtg cat gtt ctt cca gaa ggt gca cag cca caa acc caa gca 211 Thr Phe Val His Val Leu Pro Glu Gly Ala Gln Pro Gln Thr Gln Ala 25 30 35 gtt ctt ggc tcc aac atg tgc cac gtg cag gta gaa att gat gag gaa 259 Val Leu Gly Ser Asn Met Cys His Val Gln Val Glu Ile Asp Glu Glu 40 45 50 gca ggc aaa gtc ctt gtt acc tcc gca atc gat aac ctc acc aag gga 307 Ala Gly Lys Val Leu Val Thr Ser Ala Ile Asp Asn Leu Thr Lys Gly 55 60 65 act gcc ggc gcc gct gtt cag tgc atg aac tta agc gtt ggt ttt gat 355 Thr Ala Gly Ala Ala Val Gln Cys Met Asn Leu Ser Val Gly Phe Asp 70 75 80 85 gag gca gca ggc ctg cca cag gtc ggc gtc gca cct taaagtagcg 401 Glu Ala Ala Gly Leu Pro Gln Val Gly Val Ala Pro 90 95 ccttaaagcg gcg 414 <210> 326 <211> 97 <212> PRT <213> Corynebacterium glutamicum <400> 326 Leu Lys Glu Gly Val Thr Ala Glu Gln Ala Arg Ala Val Tyr Glu Glu 1 5 10 15 Phe Tyr Ala Gln Glu Thr Phe Val His Val Leu Pro Glu Gly Ala Gln 20 25 30 Pro Gln Thr Gln Ala Val Leu Gly Ser Asn Met Cys His Val Gln Val 35 40 45 Glu Ile Asp Glu Glu Ala Gly Lys Val Leu Val Thr Ser Ala Ile Asp 50 55 60 Asn Leu Thr Lys Gly Thr Ala Gly Ala Ala Val Gln Cys Met Asn Leu 65 70 75 80 Ser Val Gly Phe Asp Glu Ala Ala Gly Leu Pro Gln Val Gly Val Ala 85 90 95 Pro <210> 327 <211> 1296 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1273) <223> RXA02157 <400> 327 gggtggaatt ggcacgatgg tgctgccgga tgtttttgat cgggagaatt atcctgaagg 60 caccgttttt agaaaagacg acaaggatgg ggaactgtaa atg agc acg ctg gaa 115 Met Ser Thr Leu Glu 1 5 act tgg cca cag gtc att att aat acg tac ggc acc cca cca gtt gag 163 Thr Trp Pro Gln Val Ile Ile Asn Thr Tyr Gly Thr Pro Pro Val Glu 10 15 20 ctg gtg tcc ggc aag ggc gca acc gtc act gat gac cag ggc aat gtc 211 Leu Val Ser Gly Lys Gly Ala Thr Val Thr Asp Asp Gln Gly Asn Val 25 30 35 tac atc gac ttg ctc gcg ggc atc gca gtc aac gcg ttg ggc cac gcc 259 Tyr Ile Asp Leu Leu Ala Gly Ile Ala Val Asn Ala Leu Gly His Ala 40 45 50 cac ccg gcg atc atc gag gcg gtc acc aac cag atc ggc caa ctt ggt 307 His Pro Ala Ile Ile Glu Ala Val Thr Asn Gln Ile Gly Gln Leu Gly 55 60 65 cac gtc tca aac ttg ttc gca tcc agg ccc gtc gtc gag gtc gcc gag 355 His Val Ser Asn Leu Phe Ala Ser Arg Pro Val Val Glu Val Ala Glu 70 75 80 85 gag ctc atc aag cgt ttt tcg ctt gac gac gcc acc ctc gcc gcg caa 403 Glu Leu Ile Lys Arg Phe Ser Leu Asp Asp Ala Thr Leu Ala Ala Gln 90 95 100 acc cgg gtt ttc ttc tgc aac tcg ggc gcc gaa gca aac gag gct gct 451 Thr Arg Val Phe Phe Cys Asn Ser Gly Ala Glu Ala Asn Glu Ala Ala 105 110 115 ttc aag att gca cgc ttg act ggt cgt tcc cgg att ctg gct gca gtt 499 Phe Lys Ile Ala Arg Leu Thr Gly Arg Ser Arg Ile Leu Ala Ala Val 120 125 130 cat ggt ttc cac ggc cgc acc atg ggt tcc ctc gcg ctg act ggc cag 547 His Gly Phe His Gly Arg Thr Met Gly Ser Leu Ala Leu Thr Gly Gln 135 140 145 cca gac aag cgt gaa gcg ttc ctg cca atg cca agc ggt gtg gag ttc 595 Pro Asp Lys Arg Glu Ala Phe Leu Pro Met Pro Ser Gly Val Glu Phe 150 155 160 165 tac cct tac ggc gac acc gat tac ttg cgc aaa atg gta gaa acc aac 643 Tyr Pro Tyr Gly Asp Thr Asp Tyr Leu Arg Lys Met Val Glu Thr Asn 170 175 180 cca acg gat gtg gct gct atc ttc ctc gag cca atc cag ggt gaa acg 691 Pro Thr Asp Val Ala Ala Ile Phe Leu Glu Pro Ile Gln Gly Glu Thr 185 190 195 ggc gtt gtt cca gca cct gaa gga ttc ctc aag gca gtg cgc gag ctg 739 Gly Val Val Pro Ala Pro Glu Gly Phe Leu Lys Ala Val Arg Glu Leu 200 205 210 tgc gat gag tac ggc atc ttg atg atc acc gat gaa gtc cag act ggc 787 Cys Asp Glu Tyr Gly Ile Leu Met Ile Thr Asp Glu Val Gln Thr Gly 215 220 225 gtt ggc cgt acc ggc gat ttc ttt gca cat cag cac gat ggc gtt gtt 835 Val Gly Arg Thr Gly Asp Phe Phe Ala His Gln His Asp Gly Val Val 230 235 240 245 ccc gat gtg gtg acc atg gcc aag gga ctt ggc ggc ggt ctt ccc atc 883 Pro Asp Val Val Thr Met Ala Lys Gly Leu Gly Gly Gly Leu Pro Ile 250 255 260 ggt gct tgt ttg gcc act ggc cgt gca gct gaa ttg atg acc cca ggc 931 Gly Ala Cys Leu Ala Thr Gly Arg Ala Ala Glu Leu Met Thr Pro Gly 265 270 275 aag cac ggc acc act ttc ggt ggc aac cca gtt gct tgt gca gct gcc 979 Lys His Gly Thr Thr Phe Gly Gly Asn Pro Val Ala Cys Ala Ala Ala 280 285 290 aag gca gtg ctg tct gtt gtc gat gac gct ttc tgc gca gaa gtt gcc 1027 Lys Ala Val Leu Ser Val Val Asp Asp Ala Phe Cys Ala Glu Val Ala 295 300 305 cgc aag ggc gag ctg ttc aag gaa ctt ctt gcc aag gtt gac ggc gtt 1075 Arg Lys Gly Glu Leu Phe Lys Glu Leu Leu Ala Lys Val Asp Gly Val 310 315 320 325 gta gac gtc cgt ggc agg ggc ttg atg ttg ggc gtg gtg ctg gag cgc 1123 Val Asp Val Arg Gly Arg Gly Leu Met Leu Gly Val Val Leu Glu Arg 330 335 340 gac gtc gca aag caa gct gtt ctt gat ggt ttt aag cac ggc gtt att 1171 Asp Val Ala Lys Gln Ala Val Leu Asp Gly Phe Lys His Gly Val Ile 345 350 355 ttg aat gca ccg gcg gac aac att atc cgt ttg acc ccg ccg ctg gtg 1219 Leu Asn Ala Pro Ala Asp Asn Ile Ile Arg Leu Thr Pro Pro Leu Val 360 365 370 atc acc gac gaa gaa atc gca gac gca gtc aag gct att gcc gag aca 1267 Ile Thr Asp Glu Glu Ile Ala Asp Ala Val Lys Ala Ile Ala Glu Thr 375 380 385 atc gca taaaggactc aaacttatga ctt 1296 Ile Ala 390 <210> 328 <211> 391 <212> PRT <213> Corynebacterium glutamicum <400> 328 Met Ser Thr Leu Glu Thr Trp Pro Gln Val Ile Ile Asn Thr Tyr Gly 1 5 10 15 Thr Pro Pro Val Glu Leu Val Ser Gly Lys Gly Ala Thr Val Thr Asp 20 25 30 Asp Gln Gly Asn Val Tyr Ile Asp Leu Leu Ala Gly Ile Ala Val Asn 35 40 45 Ala Leu Gly His Ala His Pro Ala Ile Ile Glu Ala Val Thr Asn Gln 50 55 60 Ile Gly Gln Leu Gly His Val Ser Asn Leu Phe Ala Ser Arg Pro Val 65 70 75 80 Val Glu Val Ala Glu Glu Leu Ile Lys Arg Phe Ser Leu Asp Asp Ala 85 90 95 Thr Leu Ala Ala Gln Thr Arg Val Phe Phe Cys Asn Ser Gly Ala Glu 100 105 110 Ala Asn Glu Ala Ala Phe Lys Ile Ala Arg Leu Thr Gly Arg Ser Arg 115 120 125 Ile Leu Ala Ala Val His Gly Phe His Gly Arg Thr Met Gly Ser Leu 130 135 140 Ala Leu Thr Gly Gln Pro Asp Lys Arg Glu Ala Phe Leu Pro Met Pro 145 150 155 160 Ser Gly Val Glu Phe Tyr Pro Tyr Gly Asp Thr Asp Tyr Leu Arg Lys 165 170 175 Met Val Glu Thr Asn Pro Thr Asp Val Ala Ala Ile Phe Leu Glu Pro 180 185 190 Ile Gln Gly Glu Thr Gly Val Val Pro Ala Pro Glu Gly Phe Leu Lys 195 200 205 Ala Val Arg Glu Leu Cys Asp Glu Tyr Gly Ile Leu Met Ile Thr Asp 210 215 220 Glu Val Gln Thr Gly Val Gly Arg Thr Gly Asp Phe Phe Ala His Gln 225 230 235 240 His Asp Gly Val Val Pro Asp Val Val Thr Met Ala Lys Gly Leu Gly 245 250 255 Gly Gly Leu Pro Ile Gly Ala Cys Leu Ala Thr Gly Arg Ala Ala Glu 260 265 270 Leu Met Thr Pro Gly Lys His Gly Thr Thr Phe Gly Gly Asn Pro Val 275 280 285 Ala Cys Ala Ala Ala Lys Ala Val Leu Ser Val Val Asp Asp Ala Phe 290 295 300 Cys Ala Glu Val Ala Arg Lys Gly Glu Leu Phe Lys Glu Leu Leu Ala 305 310 315 320 Lys Val Asp Gly Val Val Asp Val Arg Gly Arg Gly Leu Met Leu Gly 325 330 335 Val Val Leu Glu Arg Asp Val Ala Lys Gln Ala Val Leu Asp Gly Phe 340 345 350 Lys His Gly Val Ile Leu Asn Ala Pro Ala Asp Asn Ile Ile Arg Leu 355 360 365 Thr Pro Pro Leu Val Ile Thr Asp Glu Glu Ile Ala Asp Ala Val Lys 370 375 380 Ala Ile Ala Glu Thr Ile Ala 385 390 <210> 329 <211> 1491 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1468) <223> RXS02970 <400> 329 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc gtg tgg ccg atg atc tcc ggc aac cga ttc cac 1363 Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser Gly Asn Arg Phe His 410 415 420 atc gcg ccg ccg ctg acc acc act gat gac gaa ttg gta gca ctg ctg 1411 Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu Leu Val Ala Leu Leu 425 430 435 gac gcg gtg gaa gct gca gcc caa gct gtc gag ctg acc ttc gct ggg 1459 Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu Leu Thr Phe Ala Gly 440 445 450 gcg ttg ttc taagttttct agataacaag gcc 1491 Ala Leu Phe 455 <210> 330 <211> 456 <212> PRT <213> Corynebacterium glutamicum <400> 330 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser 405 410 415 Gly Asn Arg Phe His Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu 420 425 430 Leu Val Ala Leu Leu Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu 435 440 445 Leu Thr Phe Ala Gly Ala Leu Phe 450 455 <210> 331 <211> 1330 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1330) <223> FRXA01009 <400> 331 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc 1330 Phe Lys Glu Arg Gly 410 <210> 332 <211> 410 <212> PRT <213> Corynebacterium glutamicum <400> 332 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly 405 410 <210> 333 <211> 1080 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1057) <223> RXA02158 <400> 333 aacattatcc gtttgacccc gccgctggtg atcaccgacg aagaaatcgc agacgcagtc 60 aaggctattg ccgagacaat cgcataaagg actcaaactt atg act tca caa cca 115 Met Thr Ser Gln Pro 1 5 cag gtt cgc cat ttt ctg gct gat gat gat ctc acc cct gca gag cag 163 Gln Val Arg His Phe Leu Ala Asp Asp Asp Leu Thr Pro Ala Glu Gln 10 15 20 gca gag gtt ttg acc cta gcc gca aag ctc aag gca gcg ccg ttt tcg 211 Ala Glu Val Leu Thr Leu Ala Ala Lys Leu Lys Ala Ala Pro Phe Ser 25 30 35 gag cgt cca ctc gag gga cca aag tcc gtt gca gtt ctt ttt gat aag 259 Glu Arg Pro Leu Glu Gly Pro Lys Ser Val Ala Val Leu Phe Asp Lys 40 45 50 act tca act cgt act cgc ttc tcc ttc gac gcg ggc atc gct cat ttg 307 Thr Ser Thr Arg Thr Arg Phe Ser Phe Asp Ala Gly Ile Ala His Leu 55 60 65 ggt gga cac gcc atc gtc gtg gat tcc ggt agc tca cag atg ggt aag 355 Gly Gly His Ala Ile Val Val Asp Ser Gly Ser Ser Gln Met Gly Lys 70 75 80 85 ggc gag tcc ctg cag gac acc gca gct gta ttg tcc cgc tac gtg gaa 403 Gly Glu Ser Leu Gln Asp Thr Ala Ala Val Leu Ser Arg Tyr Val Glu 90 95 100 gca att gtg tgg cgc acc tac gca cac agc aat ttc cac gcc atg gcg 451 Ala Ile Val Trp Arg Thr Tyr Ala His Ser Asn Phe His Ala Met Ala 105 110 115 gag acg tcc act gtg ccg ctg gtg aac tcc ttg tcc gat gat ctg cac 499 Glu Thr Ser Thr Val Pro Leu Val Asn Ser Leu Ser Asp Asp Leu His 120 125 130 cca tgc cag att ctg gct gat ctg cag act atc gtg gaa aac ctc agc 547 Pro Cys Gln Ile Leu Ala Asp Leu Gln Thr Ile Val Glu Asn Leu Ser 135 140 145 cct gaa gaa ggc cca gca ggc ctt aag ggt aag aag gct gtg tac ctg 595 Pro Glu Glu Gly Pro Ala Gly Leu Lys Gly Lys Lys Ala Val Tyr Leu 150 155 160 165 ggc gat ggc gac aac aac atg gcc aac tcc tac atg att ggc ttt gcc 643 Gly Asp Gly Asp Asn Asn Met Ala Asn Ser Tyr Met Ile Gly Phe Ala 170 175 180 acc gcg ggc atg gat att tcc atc atc gct cct gaa ggg ttc cag cct 691 Thr Ala Gly Met Asp Ile Ser Ile Ile Ala Pro Glu Gly Phe Gln Pro 185 190 195 cgt gcg gaa ttc gtg gag cgc gcg gaa aag cgt ggc cag gaa acc ggc 739 Arg Ala Glu Phe Val Glu Arg Ala Glu Lys Arg Gly Gln Glu Thr Gly 200 205 210 gcg aag gtt gtt gtc acc gac agc ctc gac gag gtt gcc ggc gcc gat 787 Ala Lys Val Val Val Thr Asp Ser Leu Asp Glu Val Ala Gly Ala Asp 215 220 225 gtt gtc atc acc gat acc tgg gta tcc atg ggt atg gaa aac gac ggc 835 Val Val Ile Thr Asp Thr Trp Val Ser Met Gly Met Glu Asn Asp Gly 230 235 240 245 atc gat cgc acc aca cct ttc gtt cct tac cag gtc aac gat gag gtc 883 Ile Asp Arg Thr Thr Pro Phe Val Pro Tyr Gln Val Asn Asp Glu Val 250 255 260 atg gcg aaa gct aac gac ggc gcc atc ttc ctg cac tgc ctt cct gcc 931 Met Ala Lys Ala Asn Asp Gly Ala Ile Phe Leu His Cys Leu Pro Ala 265 270 275 tac cgt ggc aaa gaa gtg gca gcc tcc gtg att gat gga cca gcg tcc 979 Tyr Arg Gly Lys Glu Val Ala Ala Ser Val Ile Asp Gly Pro Ala Ser 280 285 290 aaa gtt ttc gat gaa gca gaa aac cgc ctc cac gct cag aaa gca ctg 1027 Lys Val Phe Asp Glu Ala Glu Asn Arg Leu His Ala Gln Lys Ala Leu 295 300 305 ctg gtg tgg ctg ctg gcc aac cag ccg agg taagacatgt cccttggctc 1077 Leu Val Trp Leu Leu Ala Asn Gln Pro Arg 310 315 aac 1080 <210> 334 <211> 319 <212> PRT <213> Corynebacterium glutamicum <400> 334 Met Thr Ser Gln Pro Gln Val Arg His Phe Leu Ala Asp Asp Asp Leu 1 5 10 15 Thr Pro Ala Glu Gln Ala Glu Val Leu Thr Leu Ala Ala Lys Leu Lys 20 25 30 Ala Ala Pro Phe Ser Glu Arg Pro Leu Glu Gly Pro Lys Ser Val Ala 35 40 45 Val Leu Phe Asp Lys Thr Ser Thr Arg Thr Arg Phe Ser Phe Asp Ala 50 55 60 Gly Ile Ala His Leu Gly Gly His Ala Ile Val Val Asp Ser Gly Ser 65 70 75 80 Ser Gln Met Gly Lys Gly Glu Ser Leu Gln Asp Thr Ala Ala Val Leu 85 90 95 Ser Arg Tyr Val Glu Ala Ile Val Trp Arg Thr Tyr Ala His Ser Asn 100 105 110 Phe His Ala Met Ala Glu Thr Ser Thr Val Pro Leu Val Asn Ser Leu 115 120 125 Ser Asp Asp Leu His Pro Cys Gln Ile Leu Ala Asp Leu Gln Thr Ile 130 135 140 Val Glu Asn Leu Ser Pro Glu Glu Gly Pro Ala Gly Leu Lys Gly Lys 145 150 155 160 Lys Ala Val Tyr Leu Gly Asp Gly Asp Asn Asn Met Ala Asn Ser Tyr 165 170 175 Met Ile Gly Phe Ala Thr Ala Gly Met Asp Ile Ser Ile Ile Ala Pro 180 185 190 Glu Gly Phe Gln Pro Arg Ala Glu Phe Val Glu Arg Ala Glu Lys Arg 195 200 205 Gly Gln Glu Thr Gly Ala Lys Val Val Val Thr Asp Ser Leu Asp Glu 210 215 220 Val Ala Gly Ala Asp Val Val Ile Thr Asp Thr Trp Val Ser Met Gly 225 230 235 240 Met Glu Asn Asp Gly Ile Asp Arg Thr Thr Pro Phe Val Pro Tyr Gln 245 250 255 Val Asn Asp Glu Val Met Ala Lys Ala Asn Asp Gly Ala Ile Phe Leu 260 265 270 His Cys Leu Pro Ala Tyr Arg Gly Lys Glu Val Ala Ala Ser Val Ile 275 280 285 Asp Gly Pro Ala Ser Lys Val Phe Asp Glu Ala Glu Asn Arg Leu His 290 295 300 Ala Gln Lys Ala Leu Leu Val Trp Leu Leu Ala Asn Gln Pro Arg 305 310 315 <210> 335 <211> 1326 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1303) <223> RXA02160 <400> 335 ttttcgagga ataccaaccc tttcaacaca ataattttct ttaaacatcc ttgctgtcca 60 ccacggctgg caaggaactt aaaatgaagg agcacacctc atg act aac cgc atc 115 Met Thr Asn Arg Ile 1 5 gtt ctt gca tac tcc ggc ggt ctg gac acc act gtg gca att cca tac 163 Val Leu Ala Tyr Ser Gly Gly Leu Asp Thr Thr Val Ala Ile Pro Tyr 10 15 20 ctg aag aag atg att gat ggt gaa gtc atc gca gtt tcc ctc gac ctg 211 Leu Lys Lys Met Ile Asp Gly Glu Val Ile Ala Val Ser Leu Asp Leu 25 30 35 ggc cag ggt gga gag aac atg gac aac gtt cgc cag cgt gca ttg gat 259 Gly Gln Gly Gly Glu Asn Met Asp Asn Val Arg Gln Arg Ala Leu Asp 40 45 50 gcc ggt gca gct gag tcc atc gtt gtt gat gca aag gat gag ttc gct 307 Ala Gly Ala Ala Glu Ser Ile Val Val Asp Ala Lys Asp Glu Phe Ala 55 60 65 gag gag tac tgc ctg cca acc atc aag gca aac ggc atg tac atg aag 355 Glu Glu Tyr Cys Leu Pro Thr Ile Lys Ala Asn Gly Met Tyr Met Lys 70 75 80 85 cag tac cca ctg gtt tct gca atc tcc cgc cca ctg atc gtc aag cac 403 Gln Tyr Pro Leu Val Ser Ala Ile Ser Arg Pro Leu Ile Val Lys His 90 95 100 ctc gtt gag gct ggc aag cag ttc aac ggt acc cac gtt gca cac ggc 451 Leu Val Glu Ala Gly Lys Gln Phe Asn Gly Thr His Val Ala His Gly 105 110 115 tgc act ggt aag ggc aac gac cag gtt cgt ttc gag gtc ggc ttc atg 499 Cys Thr Gly Lys Gly Asn Asp Gln Val Arg Phe Glu Val Gly Phe Met 120 125 130 gac acc gat cca aac ctg gag atc att gca cct gct cgt gac ttc gca 547 Asp Thr Asp Pro Asn Leu Glu Ile Ile Ala Pro Ala Arg Asp Phe Ala 135 140 145 tgg acc cgc gac aag gct atc gcc ttc gcc gag gag aac aac gtt cca 595 Trp Thr Arg Asp Lys Ala Ile Ala Phe Ala Glu Glu Asn Asn Val Pro 150 155 160 165 atc gag cag tcc gtg aag tcc cca ttc tcc atc gac cag aac gtc tgg 643 Ile Glu Gln Ser Val Lys Ser Pro Phe Ser Ile Asp Gln Asn Val Trp 170 175 180 ggc cgc gct att gag acc ggt tac ctg gaa gat ctg tgg aat gct cca 691 Gly Arg Ala Ile Glu Thr Gly Tyr Leu Glu Asp Leu Trp Asn Ala Pro 185 190 195 acc aag gac atc tac gca tac acc gag gat cca gct ctg ggt aac gct 739 Thr Lys Asp Ile Tyr Ala Tyr Thr Glu Asp Pro Ala Leu Gly Asn Ala 200 205 210 cca gat gag gtc atc atc tcc ttc gag ggt ggc aag cca gtc tcc atc 787 Pro Asp Glu Val Ile Ile Ser Phe Glu Gly Gly Lys Pro Val Ser Ile 215 220 225 gat ggc cgt cca gtc tcc gta ctg cag gct att gaa gag ctg aac cgt 835 Asp Gly Arg Pro Val Ser Val Leu Gln Ala Ile Glu Glu Leu Asn Arg 230 235 240 245 cgt gca ggc gca cag ggc gtt ggc cgc ctt gac atg gtt gag gac cgt 883 Arg Ala Gly Ala Gln Gly Val Gly Arg Leu Asp Met Val Glu Asp Arg 250 255 260 ctc gtg ggc atc aag tcc cgc gaa atc tac gaa gca cca ggc gca atc 931 Leu Val Gly Ile Lys Ser Arg Glu Ile Tyr Glu Ala Pro Gly Ala Ile 265 270 275 gca ctg att aag gct cac gag gct ttg gaa gat gtc acc atc gag cgc 979 Ala Leu Ile Lys Ala His Glu Ala Leu Glu Asp Val Thr Ile Glu Arg 280 285 290 gaa ctg gct cgc tac aag cgc ggc gtt gac gca cgt tgg gct gag gaa 1027 Glu Leu Ala Arg Tyr Lys Arg Gly Val Asp Ala Arg Trp Ala Glu Glu 295 300 305 gta tac gac ggc ctg tgg ttc gga cct ctg aag cgc tcc ctg gac gcg 1075 Val Tyr Asp Gly Leu Trp Phe Gly Pro Leu Lys Arg Ser Leu Asp Ala 310 315 320 325 ttc att gat tcc acc cag gag cac gtc acc ggc gat atc cgc atg gtt 1123 Phe Ile Asp Ser Thr Gln Glu His Val Thr Gly Asp Ile Arg Met Val 330 335 340 ctg cac gca ggt tcc atc acc atc aat ggt cgt cgt tcc agc cac tcc 1171 Leu His Ala Gly Ser Ile Thr Ile Asn Gly Arg Arg Ser Ser His Ser 345 350 355 ctg tac gac ttc aac ctg gct acc tac gac acc ggc gac acc ttc gac 1219 Leu Tyr Asp Phe Asn Leu Ala Thr Tyr Asp Thr Gly Asp Thr Phe Asp 360 365 370 cag acc ctg gct aag ggc ttt gtc cag ctg cac ggt ctg tcc tcc aag 1267 Gln Thr Leu Ala Lys Gly Phe Val Gln Leu His Gly Leu Ser Ser Lys 375 380 385 atc gct aac aag cgc gat cgc gaa gct ggc aac aac taagccacct 1313 Ile Ala Asn Lys Arg Asp Arg Glu Ala Gly Asn Asn 390 395 400 tttcaagcat cca 1326 <210> 336 <211> 401 <212> PRT <213> Corynebacterium glutamicum <400> 336 Met Thr Asn Arg Ile Val Leu Ala Tyr Ser Gly Gly Leu Asp Thr Thr 1 5 10 15 Val Ala Ile Pro Tyr Leu Lys Lys Met Ile Asp Gly Glu Val Ile Ala 20 25 30 Val Ser Leu Asp Leu Gly Gln Gly Gly Glu Asn Met Asp Asn Val Arg 35 40 45 Gln Arg Ala Leu Asp Ala Gly Ala Ala Glu Ser Ile Val Val Asp Ala 50 55 60 Lys Asp Glu Phe Ala Glu Glu Tyr Cys Leu Pro Thr Ile Lys Ala Asn 65 70 75 80 Gly Met Tyr Met Lys Gln Tyr Pro Leu Val Ser Ala Ile Ser Arg Pro 85 90 95 Leu Ile Val Lys His Leu Val Glu Ala Gly Lys Gln Phe Asn Gly Thr 100 105 110 His Val Ala His Gly Cys Thr Gly Lys Gly Asn Asp Gln Val Arg Phe 115 120 125 Glu Val Gly Phe Met Asp Thr Asp Pro Asn Leu Glu Ile Ile Ala Pro 130 135 140 Ala Arg Asp Phe Ala Trp Thr Arg Asp Lys Ala Ile Ala Phe Ala Glu 145 150 155 160 Glu Asn Asn Val Pro Ile Glu Gln Ser Val Lys Ser Pro Phe Ser Ile 165 170 175 Asp Gln Asn Val Trp Gly Arg Ala Ile Glu Thr Gly Tyr Leu Glu Asp 180 185 190 Leu Trp Asn Ala Pro Thr Lys Asp Ile Tyr Ala Tyr Thr Glu Asp Pro 195 200 205 Ala Leu Gly Asn Ala Pro Asp Glu Val Ile Ile Ser Phe Glu Gly Gly 210 215 220 Lys Pro Val Ser Ile Asp Gly Arg Pro Val Ser Val Leu Gln Ala Ile 225 230 235 240 Glu Glu Leu Asn Arg Arg Ala Gly Ala Gln Gly Val Gly Arg Leu Asp 245 250 255 Met Val Glu Asp Arg Leu Val Gly Ile Lys Ser Arg Glu Ile Tyr Glu 260 265 270 Ala Pro Gly Ala Ile Ala Leu Ile Lys Ala His Glu Ala Leu Glu Asp 275 280 285 Val Thr Ile Glu Arg Glu Leu Ala Arg Tyr Lys Arg Gly Val Asp Ala 290 295 300 Arg Trp Ala Glu Glu Val Tyr Asp Gly Leu Trp Phe Gly Pro Leu Lys 305 310 315 320 Arg Ser Leu Asp Ala Phe Ile Asp Ser Thr Gln Glu His Val Thr Gly 325 330 335 Asp Ile Arg Met Val Leu His Ala Gly Ser Ile Thr Ile Asn Gly Arg 340 345 350 Arg Ser Ser His Ser Leu Tyr Asp Phe Asn Leu Ala Thr Tyr Asp Thr 355 360 365 Gly Asp Thr Phe Asp Gln Thr Leu Ala Lys Gly Phe Val Gln Leu His 370 375 380 Gly Leu Ser Ser Lys Ile Ala Asn Lys Arg Asp Arg Glu Ala Gly Asn 385 390 395 400 Asn <210> 337 <211> 1554 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1531) <223> RXN02162 <400> 337 gatcgctaac aagcgcgatc gcgaagctgg caacaactaa gccacctttt caagcatcca 60 gactagaact tcaagtattt agaaagtaga agaacaccac atg gaa cag cac gga 115 Met Glu Gln His Gly 1 5 acc aat gaa ggt gcg ctg tgg ggc ggc cgc ttc tcc ggt gga ccc tcc 163 Thr Asn Glu Gly Ala Leu Trp Gly Gly Arg Phe Ser Gly Gly Pro Ser 10 15 20 gag gcc atg ttc gcc ttg agt gtc tcc act cat ttc gac tgg gtt ttg 211 Glu Ala Met Phe Ala Leu Ser Val Ser Thr His Phe Asp Trp Val Leu 25 30 35 gcc cct tat gat gtg ttg gcc tcc aag gca cac gcc aag gtt ttg cac 259 Ala Pro Tyr Asp Val Leu Ala Ser Lys Ala His Ala Lys Val Leu His 40 45 50 caa gca gat cta ctt tct gat gaa gat cta gcc acc atg ctg gct ggg 307 Gln Ala Asp Leu Leu Ser Asp Glu Asp Leu Ala Thr Met Leu Ala Gly 55 60 65 ctt gat cag ctg ggc aag gat gtc gcc gac gga acc ttc ggt ccg ctg 355 Leu Asp Gln Leu Gly Lys Asp Val Ala Asp Gly Thr Phe Gly Pro Leu 70 75 80 85 cct tct gat gag gat gtg cac ggc gcg atg gaa cgc ggt gtg att gac 403 Pro Ser Asp Glu Asp Val His Gly Ala Met Glu Arg Gly Val Ile Asp 90 95 100 cgc gtt ggt cct gag gtg ggc ggc cgt ctg cgc gct ggt cgt tcc cgc 451 Arg Val Gly Pro Glu Val Gly Gly Arg Leu Arg Ala Gly Arg Ser Arg 105 110 115 aac gac cag gtg gca acc ctg ttc cgc atg tgg gtc cgc gac gca gtg 499 Asn Asp Gln Val Ala Thr Leu Phe Arg Met Trp Val Arg Asp Ala Val 120 125 130 cgc gac atc gcg ctg gga aca acc gag ctt gtc gac gcc ctc agc gcc 547 Arg Asp Ile Ala Leu Gly Thr Thr Glu Leu Val Asp Ala Leu Ser Ala 135 140 145 caa gct aag gca cat gca ggc gcg atc atg cca ggc aag acc cac ttc 595 Gln Ala Lys Ala His Ala Gly Ala Ile Met Pro Gly Lys Thr His Phe 150 155 160 165 cag gca gct cag ccg gtc ctt ctg gca cac cag ctg ctg gca cac gca 643 Gln Ala Ala Gln Pro Val Leu Leu Ala His Gln Leu Leu Ala His Ala 170 175 180 cag cct ttg ctg cgc gat att gat cgt atc cgt gac ctg gac aag cgt 691 Gln Pro Leu Leu Arg Asp Ile Asp Arg Ile Arg Asp Leu Asp Lys Arg 185 190 195 ctt gcg gtg tct cct tac ggt tcc ggc gca ctt gct ggt tcc tct ttg 739 Leu Ala Val Ser Pro Tyr Gly Ser Gly Ala Leu Ala Gly Ser Ser Leu 200 205 210 aag ctc aac cct gaa gca atc gct gaa gaa ctc ggc ttt gat tcc gca 787 Lys Leu Asn Pro Glu Ala Ile Ala Glu Glu Leu Gly Phe Asp Ser Ala 215 220 225 gca gat aac tcc att gat gcc acc agc tcc cgc gat ttc gca tct gaa 835 Ala Asp Asn Ser Ile Asp Ala Thr Ser Ser Arg Asp Phe Ala Ser Glu 230 235 240 245 acc gcc ttc gtg ctg gcg cag ctt gca gtg gat atg tcc cgc ttg gct 883 Thr Ala Phe Val Leu Ala Gln Leu Ala Val Asp Met Ser Arg Leu Ala 250 255 260 gaa gaa atc atc gca tgg tgc acc cca gaa ttt ggt tac atc acc ttg 931 Glu Glu Ile Ile Ala Trp Cys Thr Pro Glu Phe Gly Tyr Ile Thr Leu 265 270 275 tct gat tcc tgg tcc aca ggc agc tca atc atg ccg cag aag aag aac 979 Ser Asp Ser Trp Ser Thr Gly Ser Ser Ile Met Pro Gln Lys Lys Asn 280 285 290 cct gac gtg gca gag ctg acc cgt ggc aag tct ggt cgc ttg atc ggt 1027 Pro Asp Val Ala Glu Leu Thr Arg Gly Lys Ser Gly Arg Leu Ile Gly 295 300 305 aac ctc acc ggt ctg ctg gct acc ctg aag gca cag cct tta gcg tac 1075 Asn Leu Thr Gly Leu Leu Ala Thr Leu Lys Ala Gln Pro Leu Ala Tyr 310 315 320 325 aac cgc gac ctg cag gaa gat aag gaa cca atc gta gat tcc gtg gcg 1123 Asn Arg Asp Leu Gln Glu Asp Lys Glu Pro Ile Val Asp Ser Val Ala 330 335 340 cag ctc aac ctg ctg ctc cct gca atg act ggt ttg gtt tcc acc ttg 1171 Gln Leu Asn Leu Leu Leu Pro Ala Met Thr Gly Leu Val Ser Thr Leu 345 350 355 acc ttc aac acc gag cgc atg cgt gaa ctt gca cca gca ggt ttc acc 1219 Thr Phe Asn Thr Glu Arg Met Arg Glu Leu Ala Pro Ala Gly Phe Thr 360 365 370 ctt gcc acc gac ttg gct gag tgg atg gtg cgc cag ggc gtt cca ttc 1267 Leu Ala Thr Asp Leu Ala Glu Trp Met Val Arg Gln Gly Val Pro Phe 375 380 385 cgt gag gca cac gaa gca tcc ggc gct tgc gtg cgg atc gcg gag tcc 1315 Arg Glu Ala His Glu Ala Ser Gly Ala Cys Val Arg Ile Ala Glu Ser 390 395 400 405 agg gga gtg gac ctt atc gat ctc act gat gaa gaa ctc agt ggc gtt 1363 Arg Gly Val Asp Leu Ile Asp Leu Thr Asp Glu Glu Leu Ser Gly Val 410 415 420 gat gca cgt ctg acc cca gag gta cgg gaa gtg ctc acc att gat ggt 1411 Asp Ala Arg Leu Thr Pro Glu Val Arg Glu Val Leu Thr Ile Asp Gly 425 430 435 gca gtg gct tcc cgt gca acg cgc ggt gga acc gcg ggc gtg cgg gtt 1459 Ala Val Ala Ser Arg Ala Thr Arg Gly Gly Thr Ala Gly Val Arg Val 440 445 450 gcg gag caa cgc gca cgt gtc gat gcc gca agt acc gct cac gcg gag 1507 Ala Glu Gln Arg Ala Arg Val Asp Ala Ala Ser Thr Ala His Ala Glu 455 460 465 tgg gca cgt gcg ggg gta cgt cga taagcattag tttatggcct gtg 1554 Trp Ala Arg Ala Gly Val Arg Arg 470 475 <210> 338 <211> 477 <212> PRT <213> Corynebacterium glutamicum <400> 338 Met Glu Gln His Gly Thr Asn Glu Gly Ala Leu Trp Gly Gly Arg Phe 1 5 10 15 Ser Gly Gly Pro Ser Glu Ala Met Phe Ala Leu Ser Val Ser Thr His 20 25 30 Phe Asp Trp Val Leu Ala Pro Tyr Asp Val Leu Ala Ser Lys Ala His 35 40 45 Ala Lys Val Leu His Gln Ala Asp Leu Leu Ser Asp Glu Asp Leu Ala 50 55 60 Thr Met Leu Ala Gly Leu Asp Gln Leu Gly Lys Asp Val Ala Asp Gly 65 70 75 80 Thr Phe Gly Pro Leu Pro Ser Asp Glu Asp Val His Gly Ala Met Glu 85 90 95 Arg Gly Val Ile Asp Arg Val Gly Pro Glu Val Gly Gly Arg Leu Arg 100 105 110 Ala Gly Arg Ser Arg Asn Asp Gln Val Ala Thr Leu Phe Arg Met Trp 115 120 125 Val Arg Asp Ala Val Arg Asp Ile Ala Leu Gly Thr Thr Glu Leu Val 130 135 140 Asp Ala Leu Ser Ala Gln Ala Lys Ala His Ala Gly Ala Ile Met Pro 145 150 155 160 Gly Lys Thr His Phe Gln Ala Ala Gln Pro Val Leu Leu Ala His Gln 165 170 175 Leu Leu Ala His Ala Gln Pro Leu Leu Arg Asp Ile Asp Arg Ile Arg 180 185 190 Asp Leu Asp Lys Arg Leu Ala Val Ser Pro Tyr Gly Ser Gly Ala Leu 195 200 205 Ala Gly Ser Ser Leu Lys Leu Asn Pro Glu Ala Ile Ala Glu Glu Leu 210 215 220 Gly Phe Asp Ser Ala Ala Asp Asn Ser Ile Asp Ala Thr Ser Ser Arg 225 230 235 240 Asp Phe Ala Ser Glu Thr Ala Phe Val Leu Ala Gln Leu Ala Val Asp 245 250 255 Met Ser Arg Leu Ala Glu Glu Ile Ile Ala Trp Cys Thr Pro Glu Phe 260 265 270 Gly Tyr Ile Thr Leu Ser Asp Ser Trp Ser Thr Gly Ser Ser Ile Met 275 280 285 Pro Gln Lys Lys Asn Pro Asp Val Ala Glu Leu Thr Arg Gly Lys Ser 290 295 300 Gly Arg Leu Ile Gly Asn Leu Thr Gly Leu Leu Ala Thr Leu Lys Ala 305 310 315 320 Gln Pro Leu Ala Tyr Asn Arg Asp Leu Gln Glu Asp Lys Glu Pro Ile 325 330 335 Val Asp Ser Val Ala Gln Leu Asn Leu Leu Leu Pro Ala Met Thr Gly 340 345 350 Leu Val Ser Thr Leu Thr Phe Asn Thr Glu Arg Met Arg Glu Leu Ala 355 360 365 Pro Ala Gly Phe Thr Leu Ala Thr Asp Leu Ala Glu Trp Met Val Arg 370 375 380 Gln Gly Val Pro Phe Arg Glu Ala His Glu Ala Ser Gly Ala Cys Val 385 390 395 400 Arg Ile Ala Glu Ser Arg Gly Val Asp Leu Ile Asp Leu Thr Asp Glu 405 410 415 Glu Leu Ser Gly Val Asp Ala Arg Leu Thr Pro Glu Val Arg Glu Val 420 425 430 Leu Thr Ile Asp Gly Ala Val Ala Ser Arg Ala Thr Arg Gly Gly Thr 435 440 445 Ala Gly Val Arg Val Ala Glu Gln Arg Ala Arg Val Asp Ala Ala Ser 450 455 460 Thr Ala His Ala Glu Trp Ala Arg Ala Gly Val Arg Arg 465 470 475 <210> 339 <211> 906 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(883) <223> FRXA02161 <220> <221> misc_feature <222> 863 <223> n = a, c, g, or t <220> <221> VARIANT <222> 255 <223> Xaa = Cys, Arg, Ser, or Gly <400> 339 gatcgctaac aagcgcgatc gcgaagctgg caacaactaa gccacctttt caagcatcca 60 gactagaact tcaagtattt agaaagtaga agaacaccac atg gaa cag cac gga 115 Met Glu Gln His Gly 1 5 acc aat gaa ggt gcg ctg tgg ggc ggc cgc ttc tcc ggt gga ccc tcc 163 Thr Asn Glu Gly Ala Leu Trp Gly Gly Arg Phe Ser Gly Gly Pro Ser 10 15 20 gag gcc atg ttc gcc ttg agt gtc tcc act cat ttc gac tgg gtt ttg 211 Glu Ala Met Phe Ala Leu Ser Val Ser Thr His Phe Asp Trp Val Leu 25 30 35 gcc cct tat gat gtg ttg gcc tcc aag gca cac gcc aag gtt ttg cac 259 Ala Pro Tyr Asp Val Leu Ala Ser Lys Ala His Ala Lys Val Leu His 40 45 50 caa gca gat cta ctt tct gat gaa gat cta gcc acc atg ctg gct ggg 307 Gln Ala Asp Leu Leu Ser Asp Glu Asp Leu Ala Thr Met Leu Ala Gly 55 60 65 ctt gat cag ctg ggc aag gat gtc gcc gac gga acc ttc ggt ccg ctg 355 Leu Asp Gln Leu Gly Lys Asp Val Ala Asp Gly Thr Phe Gly Pro Leu 70 75 80 85 cct tct gat gag gat gtg cac ggc gcg atg gaa cgc ggt gtg att gac 403 Pro Ser Asp Glu Asp Val His Gly Ala Met Glu Arg Gly Val Ile Asp 90 95 100 cgc gtt ggt cct gag gtg ggc ggc cgt ctg cgc gct ggt cgt tcc cgc 451 Arg Val Gly Pro Glu Val Gly Gly Arg Leu Arg Ala Gly Arg Ser Arg 105 110 115 aac gac cag gtg gca acc ctg ttc cgc atg tgg gtc cgc gac gca gtg 499 Asn Asp Gln Val Ala Thr Leu Phe Arg Met Trp Val Arg Asp Ala Val 120 125 130 cgc gac atc gcg ctg gga aca acc gag ctt gtc gac gcc ctc agc gcc 547 Arg Asp Ile Ala Leu Gly Thr Thr Glu Leu Val Asp Ala Leu Ser Ala 135 140 145 caa gct aag gca cat gca ggc gcg atc atg cca ggc aag acc cac ttc 595 Gln Ala Lys Ala His Ala Gly Ala Ile Met Pro Gly Lys Thr His Phe 150 155 160 165 cag gca gct cag ccg gtc ctt ctg gca cac cag ctg ctg gca cac gca 643 Gln Ala Ala Gln Pro Val Leu Leu Ala His Gln Leu Leu Ala His Ala 170 175 180 cag cct ttg ctg cgc gat att gat cgt atc cgt gac ctg gac aag cgt 691 Gln Pro Leu Leu Arg Asp Ile Asp Arg Ile Arg Asp Leu Asp Lys Arg 185 190 195 ctt gcg gtg tct cct tac ggt tcc ggc gca ctt gct ggt tcc tct ttg 739 Leu Ala Val Ser Pro Tyr Gly Ser Gly Ala Leu Ala Gly Ser Ser Leu 200 205 210 aag ctc aac cct gaa gca atc gct gaa gaa ctc ggc ttt gat tcc gca 787 Lys Leu Asn Pro Glu Ala Ile Ala Glu Glu Leu Gly Phe Asp Ser Ala 215 220 225 gca gat aac tcc att gat gcc acc agc tcc cgc gat ttc gca tct gaa 835 Ala Asp Asn Ser Ile Asp Ala Thr Ser Ser Arg Asp Phe Ala Ser Glu 230 235 240 245 acc gcc ttc gtg ctg gcg cag ctt gca ngt gga tat gtc ccg ctt ggc 883 Thr Ala Phe Val Leu Ala Gln Leu Ala Xaa Gly Tyr Val Pro Leu Gly 250 255 260 tgaagaaatc atcgcatggt gca 906 <210> 340 <211> 261 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 255 <223> Xaa = Cys, Arg, Ser, or Gly <400> 340 Met Glu Gln His Gly Thr Asn Glu Gly Ala Leu Trp Gly Gly Arg Phe 1 5 10 15 Ser Gly Gly Pro Ser Glu Ala Met Phe Ala Leu Ser Val Ser Thr His 20 25 30 Phe Asp Trp Val Leu Ala Pro Tyr Asp Val Leu Ala Ser Lys Ala His 35 40 45 Ala Lys Val Leu His Gln Ala Asp Leu Leu Ser Asp Glu Asp Leu Ala 50 55 60 Thr Met Leu Ala Gly Leu Asp Gln Leu Gly Lys Asp Val Ala Asp Gly 65 70 75 80 Thr Phe Gly Pro Leu Pro Ser Asp Glu Asp Val His Gly Ala Met Glu 85 90 95 Arg Gly Val Ile Asp Arg Val Gly Pro Glu Val Gly Gly Arg Leu Arg 100 105 110 Ala Gly Arg Ser Arg Asn Asp Gln Val Ala Thr Leu Phe Arg Met Trp 115 120 125 Val Arg Asp Ala Val Arg Asp Ile Ala Leu Gly Thr Thr Glu Leu Val 130 135 140 Asp Ala Leu Ser Ala Gln Ala Lys Ala His Ala Gly Ala Ile Met Pro 145 150 155 160 Gly Lys Thr His Phe Gln Ala Ala Gln Pro Val Leu Leu Ala His Gln 165 170 175 Leu Leu Ala His Ala Gln Pro Leu Leu Arg Asp Ile Asp Arg Ile Arg 180 185 190 Asp Leu Asp Lys Arg Leu Ala Val Ser Pro Tyr Gly Ser Gly Ala Leu 195 200 205 Ala Gly Ser Ser Leu Lys Leu Asn Pro Glu Ala Ile Ala Glu Glu Leu 210 215 220 Gly Phe Asp Ser Ala Ala Asp Asn Ser Ile Asp Ala Thr Ser Ser Arg 225 230 235 240 Asp Phe Ala Ser Glu Thr Ala Phe Val Leu Ala Gln Leu Ala Xaa Gly 245 250 255 Tyr Val Pro Leu Gly 260 <210> 341 <211> 786 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(763) <223> FRXA02162 <220> <221> misc_feature <222> 94 <223> n = a, c, g, or t <400> 341 ctcggctttg attccgcagc agataactcc attgatgcca ccagctcccg cgatttcgca 60 tctgaaaccg ccttcgtgct ggcgcagctt gcangtggat atg tcc cgc ttg gct 115 Met Ser Arg Leu Ala 1 5 gaa gaa atc atc gca tgg tgc acc cca gaa ttt ggt tac atc acc ttg 163 Glu Glu Ile Ile Ala Trp Cys Thr Pro Glu Phe Gly Tyr Ile Thr Leu 10 15 20 tct gat tcc tgg tcc aca ggc agc tca atc atg ccg cag aag aag aac 211 Ser Asp Ser Trp Ser Thr Gly Ser Ser Ile Met Pro Gln Lys Lys Asn 25 30 35 cct gac gtg gca gag ctg acc cgt ggc aag tct ggt cgc ttg atc ggt 259 Pro Asp Val Ala Glu Leu Thr Arg Gly Lys Ser Gly Arg Leu Ile Gly 40 45 50 aac ctc acc ggt ctg ctg gct acc ctg aag gca cag cct tta gcg tac 307 Asn Leu Thr Gly Leu Leu Ala Thr Leu Lys Ala Gln Pro Leu Ala Tyr 55 60 65 aac cgc gac ctg cag gaa gat aag gaa cca atc gta gat tcc gtg gcg 355 Asn Arg Asp Leu Gln Glu Asp Lys Glu Pro Ile Val Asp Ser Val Ala 70 75 80 85 cag ctc aac ctg ctg ctc cct gca atg act ggt ttg gtt tcc acc ttg 403 Gln Leu Asn Leu Leu Leu Pro Ala Met Thr Gly Leu Val Ser Thr Leu 90 95 100 acc ttc aac acc gag cgc atg cgt gaa ctt gca cca gca ggt ttc acc 451 Thr Phe Asn Thr Glu Arg Met Arg Glu Leu Ala Pro Ala Gly Phe Thr 105 110 115 ctt gcc acc gac ttg gct gag tgg atg gtg cgc cag ggc gtt cca ttc 499 Leu Ala Thr Asp Leu Ala Glu Trp Met Val Arg Gln Gly Val Pro Phe 120 125 130 cgt gag gca cac gaa gca tcc ggc gct tgc gtg cgg atc gcg gag tcc 547 Arg Glu Ala His Glu Ala Ser Gly Ala Cys Val Arg Ile Ala Glu Ser 135 140 145 agg gga gtg gac ctt atc gat ctc act gat gaa gaa ctc agt ggc gtt 595 Arg Gly Val Asp Leu Ile Asp Leu Thr Asp Glu Glu Leu Ser Gly Val 150 155 160 165 gat gca cgt ctg acc cca gag gta cgg gaa gtg ctc acc att gat ggt 643 Asp Ala Arg Leu Thr Pro Glu Val Arg Glu Val Leu Thr Ile Asp Gly 170 175 180 gca gtg gct tcc cgt gca acg cgc ggt gga acc gcg ggc gtg cgg gtt 691 Ala Val Ala Ser Arg Ala Thr Arg Gly Gly Thr Ala Gly Val Arg Val 185 190 195 gcg gag caa cgc gca cgt gtc gat gcc gca agt acc gct cac gcg gag 739 Ala Glu Gln Arg Ala Arg Val Asp Ala Ala Ser Thr Ala His Ala Glu 200 205 210 tgg gca cgt gcg ggg gta cgt cga taagcattag tttatggcct gtg 786 Trp Ala Arg Ala Gly Val Arg Arg 215 220 <210> 342 <211> 221 <212> PRT <213> Corynebacterium glutamicum <400> 342 Met Ser Arg Leu Ala Glu Glu Ile Ile Ala Trp Cys Thr Pro Glu Phe 1 5 10 15 Gly Tyr Ile Thr Leu Ser Asp Ser Trp Ser Thr Gly Ser Ser Ile Met 20 25 30 Pro Gln Lys Lys Asn Pro Asp Val Ala Glu Leu Thr Arg Gly Lys Ser 35 40 45 Gly Arg Leu Ile Gly Asn Leu Thr Gly Leu Leu Ala Thr Leu Lys Ala 50 55 60 Gln Pro Leu Ala Tyr Asn Arg Asp Leu Gln Glu Asp Lys Glu Pro Ile 65 70 75 80 Val Asp Ser Val Ala Gln Leu Asn Leu Leu Leu Pro Ala Met Thr Gly 85 90 95 Leu Val Ser Thr Leu Thr Phe Asn Thr Glu Arg Met Arg Glu Leu Ala 100 105 110 Pro Ala Gly Phe Thr Leu Ala Thr Asp Leu Ala Glu Trp Met Val Arg 115 120 125 Gln Gly Val Pro Phe Arg Glu Ala His Glu Ala Ser Gly Ala Cys Val 130 135 140 Arg Ile Ala Glu Ser Arg Gly Val Asp Leu Ile Asp Leu Thr Asp Glu 145 150 155 160 Glu Leu Ser Gly Val Asp Ala Arg Leu Thr Pro Glu Val Arg Glu Val 165 170 175 Leu Thr Ile Asp Gly Ala Val Ala Ser Arg Ala Thr Arg Gly Gly Thr 180 185 190 Ala Gly Val Arg Val Ala Glu Gln Arg Ala Arg Val Asp Ala Ala Ser 195 200 205 Thr Ala His Ala Glu Trp Ala Arg Ala Gly Val Arg Arg 210 215 220 <210> 343 <211> 1269 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1246) <223> RXA02262 <400> 343 gcaccaattt cggacctgaa atccccgagg aaaccgtgcc cgacgccgtg caggtgggcg 60 tcgataagca aaaaatcgct gatactcgaa aggcctcaaa atg acc gca acc tac 115 Met Thr Ala Thr Tyr 1 5 acc act gaa acc gcc atc aat ttc ttg ttc ttg agc gaa ccg gac atg 163 Thr Thr Glu Thr Ala Ile Asn Phe Leu Phe Leu Ser Glu Pro Asp Met 10 15 20 atc gcg gcc gga gtc aaa gac gtc gcg caa tgc gtc gat gtc atg gag 211 Ile Ala Ala Gly Val Lys Asp Val Ala Gln Cys Val Asp Val Met Glu 25 30 35 gaa acg ctc gtg ctc ttg gcg cag ggc gac tac aaa atg gcc ggt ttg 259 Glu Thr Leu Val Leu Leu Ala Gln Gly Asp Tyr Lys Met Ala Gly Leu 40 45 50 aac tcc aac tcg cat ggc gcg atg atc acc ttc ccg gaa aac cca gaa 307 Asn Ser Asn Ser His Gly Ala Met Ile Thr Phe Pro Glu Asn Pro Glu 55 60 65 ttt gaa ggc atg ccc aag gac ggc ccc gac cgc cga ttc atg gcg atg 355 Phe Glu Gly Met Pro Lys Asp Gly Pro Asp Arg Arg Phe Met Ala Met 70 75 80 85 ccc gca tac ctc ggc ggg cga ttc aaa aac acc ggc gtg aag tgg tac 403 Pro Ala Tyr Leu Gly Gly Arg Phe Lys Asn Thr Gly Val Lys Trp Tyr 90 95 100 gga tcc aac gcg gaa aac aag gcc tca ggc ttg cct cgc tcg atc cac 451 Gly Ser Asn Ala Glu Asn Lys Ala Ser Gly Leu Pro Arg Ser Ile His 105 110 115 acc ttc gtc ctc aac gac acg gtc acc ggt gca ccg aag gcc atc atg 499 Thr Phe Val Leu Asn Asp Thr Val Thr Gly Ala Pro Lys Ala Ile Met 120 125 130 tcc gcg aac ctg ctg tcc gcc tac cgc acc ggc gcg gtt ccc ggc gtg 547 Ser Ala Asn Leu Leu Ser Ala Tyr Arg Thr Gly Ala Val Pro Gly Val 135 140 145 ggc gtg aag cac tta gcg gtc gcc gac gcg aca acc ttg gct gtc gtc 595 Gly Val Lys His Leu Ala Val Ala Asp Ala Thr Thr Leu Ala Val Val 150 155 160 165 gga cct ggt gtc atg gcg aaa acc atc acc gaa gcg tgc atc gca gag 643 Gly Pro Gly Val Met Ala Lys Thr Ile Thr Glu Ala Cys Ile Ala Glu 170 175 180 cgc cca gga atc acc acc atc aag atc aag gga cgc agc gaa cgc ggc 691 Arg Pro Gly Ile Thr Thr Ile Lys Ile Lys Gly Arg Ser Glu Arg Gly 185 190 195 atc aac gcc ttt gca aca tgg gcg ttg gaa aaa ttc ccc gag atc gaa 739 Ile Asn Ala Phe Ala Thr Trp Ala Leu Glu Lys Phe Pro Glu Ile Glu 200 205 210 gtg gtc gcc gtc gga tct gaa gaa gac gtg gtc aaa gac gcc gac atc 787 Val Val Ala Val Gly Ser Glu Glu Asp Val Val Lys Asp Ala Asp Ile 215 220 225 gtc atc gcc gcc acc acc acg gac gcc gcc ggc tcc tcc gcc ttc cca 835 Val Ile Ala Ala Thr Thr Thr Asp Ala Ala Gly Ser Ser Ala Phe Pro 230 235 240 245 tac ttc aaa aaa gaa tgg ctc aag ccg ggc gca ttg ctg ctg ctt cca 883 Tyr Phe Lys Lys Glu Trp Leu Lys Pro Gly Ala Leu Leu Leu Leu Pro 250 255 260 gcc gcc ggt cgc ttc gac gac gct tat ttg ctt gac gac gcc cgc ctc 931 Ala Ala Gly Arg Phe Asp Asp Ala Tyr Leu Leu Asp Asp Ala Arg Leu 265 270 275 gtt gtt gac tac atg ggg ctc tac gaa gcc tgg gca gaa gaa tac ggc 979 Val Val Asp Tyr Met Gly Leu Tyr Glu Ala Trp Ala Glu Glu Tyr Gly 280 285 290 cca cag gcc tac caa cta ctc ggc att cca gga acc cac tgg tac gac 1027 Pro Gln Ala Tyr Gln Leu Leu Gly Ile Pro Gly Thr His Trp Tyr Asp 295 300 305 ctg gcg ctg caa gga aaa ctc gac ctt gca aag att tcc cag att ggc 1075 Leu Ala Leu Gln Gly Lys Leu Asp Leu Ala Lys Ile Ser Gln Ile Gly 310 315 320 325 gat atc tgc tcc ggc aag cta ccc gga cgc acc aac gat gag gaa atc 1123 Asp Ile Cys Ser Gly Lys Leu Pro Gly Arg Thr Asn Asp Glu Glu Ile 330 335 340 atc ctc tat tcc gtc ggc ggc atg cca gta gaa gac gtc gcc tgg gca 1171 Ile Leu Tyr Ser Val Gly Gly Met Pro Val Glu Asp Val Ala Trp Ala 345 350 355 acc caa gtg tat gaa aac gcc ctg gaa aaa ggc gtc ggc acc aca ttg 1219 Thr Gln Val Tyr Glu Asn Ala Leu Glu Lys Gly Val Gly Thr Thr Leu 360 365 370 aac ctg tgg gaa tca ccc gca ctg gct tgagagaaga aacaacaatg 1266 Asn Leu Trp Glu Ser Pro Ala Leu Ala 375 380 aaa 1269 <210> 344 <211> 382 <212> PRT <213> Corynebacterium glutamicum <400> 344 Met Thr Ala Thr Tyr Thr Thr Glu Thr Ala Ile Asn Phe Leu Phe Leu 1 5 10 15 Ser Glu Pro Asp Met Ile Ala Ala Gly Val Lys Asp Val Ala Gln Cys 20 25 30 Val Asp Val Met Glu Glu Thr Leu Val Leu Leu Ala Gln Gly Asp Tyr 35 40 45 Lys Met Ala Gly Leu Asn Ser Asn Ser His Gly Ala Met Ile Thr Phe 50 55 60 Pro Glu Asn Pro Glu Phe Glu Gly Met Pro Lys Asp Gly Pro Asp Arg 65 70 75 80 Arg Phe Met Ala Met Pro Ala Tyr Leu Gly Gly Arg Phe Lys Asn Thr 85 90 95 Gly Val Lys Trp Tyr Gly Ser Asn Ala Glu Asn Lys Ala Ser Gly Leu 100 105 110 Pro Arg Ser Ile His Thr Phe Val Leu Asn Asp Thr Val Thr Gly Ala 115 120 125 Pro Lys Ala Ile Met Ser Ala Asn Leu Leu Ser Ala Tyr Arg Thr Gly 130 135 140 Ala Val Pro Gly Val Gly Val Lys His Leu Ala Val Ala Asp Ala Thr 145 150 155 160 Thr Leu Ala Val Val Gly Pro Gly Val Met Ala Lys Thr Ile Thr Glu 165 170 175 Ala Cys Ile Ala Glu Arg Pro Gly Ile Thr Thr Ile Lys Ile Lys Gly 180 185 190 Arg Ser Glu Arg Gly Ile Asn Ala Phe Ala Thr Trp Ala Leu Glu Lys 195 200 205 Phe Pro Glu Ile Glu Val Val Ala Val Gly Ser Glu Glu Asp Val Val 210 215 220 Lys Asp Ala Asp Ile Val Ile Ala Ala Thr Thr Thr Asp Ala Ala Gly 225 230 235 240 Ser Ser Ala Phe Pro Tyr Phe Lys Lys Glu Trp Leu Lys Pro Gly Ala 245 250 255 Leu Leu Leu Leu Pro Ala Ala Gly Arg Phe Asp Asp Ala Tyr Leu Leu 260 265 270 Asp Asp Ala Arg Leu Val Val Asp Tyr Met Gly Leu Tyr Glu Ala Trp 275 280 285 Ala Glu Glu Tyr Gly Pro Gln Ala Tyr Gln Leu Leu Gly Ile Pro Gly 290 295 300 Thr His Trp Tyr Asp Leu Ala Leu Gln Gly Lys Leu Asp Leu Ala Lys 305 310 315 320 Ile Ser Gln Ile Gly Asp Ile Cys Ser Gly Lys Leu Pro Gly Arg Thr 325 330 335 Asn Asp Glu Glu Ile Ile Leu Tyr Ser Val Gly Gly Met Pro Val Glu 340 345 350 Asp Val Ala Trp Ala Thr Gln Val Tyr Glu Asn Ala Leu Glu Lys Gly 355 360 365 Val Gly Thr Thr Leu Asn Leu Trp Glu Ser Pro Ala Leu Ala 370 375 380 <210> 345 <211> 1065 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1042) <223> RXA00219 <400> 345 tttgccgtac atgcgcgagc acctcctcaa cagcccgcac caccgaccaa tcacataaga 60 cacaagcact aaaacagcat taaagaaaga aagctttttc gtg gcc cgt aag aaa 115 Val Ala Arg Lys Lys 1 5 aac acg tcc gat caa tcc cgc tcc caa gct gcc aac acg ccc att gct 163 Asn Thr Ser Asp Gln Ser Arg Ser Gln Ala Ala Asn Thr Pro Ile Ala 10 15 20 ggc acc tat gag ggt gaa tat tcc gtc atc gag ttg gag gcc gat tcc 211 Gly Thr Tyr Glu Gly Glu Tyr Ser Val Ile Glu Leu Glu Ala Asp Ser 25 30 35 tac acc acc gat ggc tgg ttg atc agc att aat ggc gtg ccc agc tct 259 Tyr Thr Thr Asp Gly Trp Leu Ile Ser Ile Asn Gly Val Pro Ser Ser 40 45 50 cat att gtc ctg ggg caa ccg cag gca ctg gaa ttt gag tac atg cgg 307 His Ile Val Leu Gly Gln Pro Gln Ala Leu Glu Phe Glu Tyr Met Arg 55 60 65 tgg atc gct acc ggc gct cgg gcg ttc atc gat gcg cat cag gat gca 355 Trp Ile Ala Thr Gly Ala Arg Ala Phe Ile Asp Ala His Gln Asp Ala 70 75 80 85 tcc aag ctg cgg att act cac ctc ggc ggc ggt gcg tgc acg atg gcc 403 Ser Lys Leu Arg Ile Thr His Leu Gly Gly Gly Ala Cys Thr Met Ala 90 95 100 agg tat ttc gcg gat gtt tac ccg cag tca cgc aac act gtc gtg gaa 451 Arg Tyr Phe Ala Asp Val Tyr Pro Gln Ser Arg Asn Thr Val Val Glu 105 110 115 ttg gat gca gag ctt gcc cgc ctg tcg cgt gaa tgg ttc gac att ccg 499 Leu Asp Ala Glu Leu Ala Arg Leu Ser Arg Glu Trp Phe Asp Ile Pro 120 125 130 cgc gcg cca cgg gta aag att cgt gtg gat gat gcc cga atg gtg gca 547 Arg Ala Pro Arg Val Lys Ile Arg Val Asp Asp Ala Arg Met Val Ala 135 140 145 gaa tct ttc act ccc gca agc cgc gat gtg atc atc cgt gac gtt ttt 595 Glu Ser Phe Thr Pro Ala Ser Arg Asp Val Ile Ile Arg Asp Val Phe 150 155 160 165 gcc gga gct atc acg ccg cag aac ttc acc acc gtg gag ttc ttt gag 643 Ala Gly Ala Ile Thr Pro Gln Asn Phe Thr Thr Val Glu Phe Phe Glu 170 175 180 cac tgt cac cgt ggc ctt gct ccc ggc gga ttg tac gtt gcc aac tgt 691 His Cys His Arg Gly Leu Ala Pro Gly Gly Leu Tyr Val Ala Asn Cys 185 190 195 ggc gat cat tcg gat ctg cgc gga gct aaa tct gag ctc gcg gga atg 739 Gly Asp His Ser Asp Leu Arg Gly Ala Lys Ser Glu Leu Ala Gly Met 200 205 210 atg gag gtg ttc gag cac gtc gcg gtc atc gcc gat ccc ccg atg ctt 787 Met Glu Val Phe Glu His Val Ala Val Ile Ala Asp Pro Pro Met Leu 215 220 225 aaa ggg cgc cgt tac ggc aac atc att ttg atg ggt tca gac acc gag 835 Lys Gly Arg Arg Tyr Gly Asn Ile Ile Leu Met Gly Ser Asp Thr Glu 230 235 240 245 ttc ttt agc tcc aac agc acg gaa gcg tcc gcg att acc cgt gag ctt 883 Phe Phe Ser Ser Asn Ser Thr Glu Ala Ser Ala Ile Thr Arg Glu Leu 250 255 260 ctt ggc ggc ggc gtt cca gcg cag tac aag gat gaa tcc tgg gtg cgg 931 Leu Gly Gly Gly Val Pro Ala Gln Tyr Lys Asp Glu Ser Trp Val Arg 265 270 275 aaa ttc gcc tcg gga gcc cag gcc cgc cac gat ggg gtc tct acc ctc 979 Lys Phe Ala Ser Gly Ala Gln Ala Arg His Asp Gly Val Ser Thr Leu 280 285 290 caa atg ccg agt gat act cca caa cac cct gcg gaa acg ccg gag cat 1027 Gln Met Pro Ser Asp Thr Pro Gln His Pro Ala Glu Thr Pro Glu His 295 300 305 tca aac aca cag cca taaaaaattc cgctggcgcg tcc 1065 Ser Asn Thr Gln Pro 310 <210> 346 <211> 314 <212> PRT <213> Corynebacterium glutamicum <400> 346 Val Ala Arg Lys Lys Asn Thr Ser Asp Gln Ser Arg Ser Gln Ala Ala 1 5 10 15 Asn Thr Pro Ile Ala Gly Thr Tyr Glu Gly Glu Tyr Ser Val Ile Glu 20 25 30 Leu Glu Ala Asp Ser Tyr Thr Thr Asp Gly Trp Leu Ile Ser Ile Asn 35 40 45 Gly Val Pro Ser Ser His Ile Val Leu Gly Gln Pro Gln Ala Leu Glu 50 55 60 Phe Glu Tyr Met Arg Trp Ile Ala Thr Gly Ala Arg Ala Phe Ile Asp 65 70 75 80 Ala His Gln Asp Ala Ser Lys Leu Arg Ile Thr His Leu Gly Gly Gly 85 90 95 Ala Cys Thr Met Ala Arg Tyr Phe Ala Asp Val Tyr Pro Gln Ser Arg 100 105 110 Asn Thr Val Val Glu Leu Asp Ala Glu Leu Ala Arg Leu Ser Arg Glu 115 120 125 Trp Phe Asp Ile Pro Arg Ala Pro Arg Val Lys Ile Arg Val Asp Asp 130 135 140 Ala Arg Met Val Ala Glu Ser Phe Thr Pro Ala Ser Arg Asp Val Ile 145 150 155 160 Ile Arg Asp Val Phe Ala Gly Ala Ile Thr Pro Gln Asn Phe Thr Thr 165 170 175 Val Glu Phe Phe Glu His Cys His Arg Gly Leu Ala Pro Gly Gly Leu 180 185 190 Tyr Val Ala Asn Cys Gly Asp His Ser Asp Leu Arg Gly Ala Lys Ser 195 200 205 Glu Leu Ala Gly Met Met Glu Val Phe Glu His Val Ala Val Ile Ala 210 215 220 Asp Pro Pro Met Leu Lys Gly Arg Arg Tyr Gly Asn Ile Ile Leu Met 225 230 235 240 Gly Ser Asp Thr Glu Phe Phe Ser Ser Asn Ser Thr Glu Ala Ser Ala 245 250 255 Ile Thr Arg Glu Leu Leu Gly Gly Gly Val Pro Ala Gln Tyr Lys Asp 260 265 270 Glu Ser Trp Val Arg Lys Phe Ala Ser Gly Ala Gln Ala Arg His Asp 275 280 285 Gly Val Ser Thr Leu Gln Met Pro Ser Asp Thr Pro Gln His Pro Ala 290 295 300 Glu Thr Pro Glu His Ser Asn Thr Gln Pro 305 310 <210> 347 <211> 1662 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1639) <223> RXA01508 <400> 347 ttccgggacg tttccgtgat ctcgtggaag atcccaaact ccgttccggt gccgtcgtgg 60 ccgccgtcat cttgatcgtg gtgggaaccg taaacgctgc atg tct gat tta gga 115 Met Ser Asp Leu Gly 1 5 ccc atc tgg cgc tgg ctg tta tta gtt tcc gtc tcc att tgt gcg gca 163 Pro Ile Trp Arg Trp Leu Leu Leu Val Ser Val Ser Ile Cys Ala Ala 10 15 20 tcg ggg ctg gtc tat gag cta gcc ctg gta tcg ctt tcc acc agc ttg 211 Ser Gly Leu Val Tyr Glu Leu Ala Leu Val Ser Leu Ser Thr Ser Leu 25 30 35 aac ggt ggc gga att gta gaa acc tcc ctc atc gtc gca ggt tat gta 259 Asn Gly Gly Gly Ile Val Glu Thr Ser Leu Ile Val Ala Gly Tyr Val 40 45 50 gct gcc ctt gga ctt ggt gca ctg ctg gtc aag ccg ttt ctc aac tgg 307 Ala Ala Leu Gly Leu Gly Ala Leu Leu Val Lys Pro Phe Leu Asn Trp 55 60 65 cct gcg caa acc ttc ctc ggt gtg gaa acc ctc ctt gga ctt att ggt 355 Pro Ala Gln Thr Phe Leu Gly Val Glu Thr Leu Leu Gly Leu Ile Gly 70 75 80 85 ggt tgt tcc gcg ctg gtg ctg tat ttc acc ttc gcg acc atc ggc caa 403 Gly Cys Ser Ala Leu Val Leu Tyr Phe Thr Phe Ala Thr Ile Gly Gln 90 95 100 tcc ctg tgg att ctg gtg att gcc acc gct gca att ggc atc ctg gtc 451 Ser Leu Trp Ile Leu Val Ile Ala Thr Ala Ala Ile Gly Ile Leu Val 105 110 115 ggc gct gaa ctt cca ctg ctg atg acc atg atc cag caa ggc cgc ctc 499 Gly Ala Glu Leu Pro Leu Leu Met Thr Met Ile Gln Gln Gly Arg Leu 120 125 130 gcc gac gcc aaa acc aca gga tct ctg gtt gcc acc ttg aat gct gct 547 Ala Asp Ala Lys Thr Thr Gly Ser Leu Val Ala Thr Leu Asn Ala Ala 135 140 145 gat tac ctt ggc gca ctt tta ggt ggc ctg gcc tgg cct ttt gtg ttg 595 Asp Tyr Leu Gly Ala Leu Leu Gly Gly Leu Ala Trp Pro Phe Val Leu 150 155 160 165 ctg ccg tgg ctt ggc atg atg cgc ggt gcc gca gca gcc gga atg atc 643 Leu Pro Trp Leu Gly Met Met Arg Gly Ala Ala Ala Ala Gly Met Ile 170 175 180 aac ctc gtt gca gca cta ttc gtg ggc tgt gtg ctg ctg cga cat ttg 691 Asn Leu Val Ala Ala Leu Phe Val Gly Cys Val Leu Leu Arg His Leu 185 190 195 ctt ccg cgc acc cac ttc ttc gta tcc gtg gtg gcg ctt ctt ctc gcg 739 Leu Pro Arg Thr His Phe Phe Val Ser Val Val Ala Leu Leu Leu Ala 200 205 210 atc gca gcg cta gcc acc gtg ttg gtg aaa tcc gac ggg atc gtt gcc 787 Ile Ala Ala Leu Ala Thr Val Leu Val Lys Ser Asp Gly Ile Val Ala 215 220 225 acc gcc cgc gca cag ctc tac cgc gac ccc gtg atc tat tca cac caa 835 Thr Ala Arg Ala Gln Leu Tyr Arg Asp Pro Val Ile Tyr Ser His Gln 230 235 240 245 tct gac tac caa gac atc gta gtg aca gaa cga ggc aaa gac cga cgc 883 Ser Asp Tyr Gln Asp Ile Val Val Thr Glu Arg Gly Lys Asp Arg Arg 250 255 260 ctc tac ctc aat ggc ggt ttg cag tat tcc act cgt gac cag cat aga 931 Leu Tyr Leu Asn Gly Gly Leu Gln Tyr Ser Thr Arg Asp Gln His Arg 265 270 275 tat aca gaa tca ctg gtg tat cca agc ctt aat cca gag gca gaa tcg 979 Tyr Thr Glu Ser Leu Val Tyr Pro Ser Leu Asn Pro Glu Ala Glu Ser 280 285 290 gtg tta atc atc ggc ggt ggc gat ggc ctc gca gca cgg gaa ctc ctc 1027 Val Leu Ile Ile Gly Gly Gly Asp Gly Leu Ala Ala Arg Glu Leu Leu 295 300 305 cga ttc cca tca atg cag atc acc caa gtt gaa tta gac cca gaa gtc 1075 Arg Phe Pro Ser Met Gln Ile Thr Gln Val Glu Leu Asp Pro Glu Val 310 315 320 325 atc gaa gta gcc aac aca gtg ctg cgc tct gac aat ggg gga gcg atg 1123 Ile Glu Val Ala Asn Thr Val Leu Arg Ser Asp Asn Gly Gly Ala Met 330 335 340 gaa gat ccc cgc gtc tcc atc atc gtt gac gac gct ttc acc tgg ctg 1171 Glu Asp Pro Arg Val Ser Ile Ile Val Asp Asp Ala Phe Thr Trp Leu 345 350 355 cgc tcc ggc gga aat aat ggc gaa act tac gat tcc atc atc atc gat 1219 Arg Ser Gly Gly Asn Asn Gly Glu Thr Tyr Asp Ser Ile Ile Ile Asp 360 365 370 ctt ccc gac cca aac aac gac acc atg gcc agg ctg tat tca gaa gag 1267 Leu Pro Asp Pro Asn Asn Asp Thr Met Ala Arg Leu Tyr Ser Glu Glu 375 380 385 ttc tac acc ttg gcc cga gca cga ctg aac gaa caa ggc cgc atg gtg 1315 Phe Tyr Thr Leu Ala Arg Ala Arg Leu Asn Glu Gln Gly Arg Met Val 390 395 400 405 gtg caa tcc tcc agc gcc tac acc act cca gat gtg ttc tgg cga gtt 1363 Val Gln Ser Ser Ser Ala Tyr Thr Thr Pro Asp Val Phe Trp Arg Val 410 415 420 gga gca acc ttg aaa tcg gcg ggc tgt gaa caa gtc atc cca tat cac 1411 Gly Ala Thr Leu Lys Ser Ala Gly Cys Glu Gln Val Ile Pro Tyr His 425 430 435 gtg cat gtt ccc aca ttt ggc gac tgg ggc ttc caa ctg tgt ggc cct 1459 Val His Val Pro Thr Phe Gly Asp Trp Gly Phe Gln Leu Cys Gly Pro 440 445 450 gcc gac atg gaa tta gag ctt cgg gaa gac acc ccg cca ctg act ttc 1507 Ala Asp Met Glu Leu Glu Leu Arg Glu Asp Thr Pro Pro Leu Thr Phe 455 460 465 ctt aat gat gaa gtt ctg gtg gct gct ggg gtg ttt ggg ttg gat aat 1555 Leu Asn Asp Glu Val Leu Val Ala Ala Gly Val Phe Gly Leu Asp Asn 470 475 480 485 cag cct cgt gaa ttg gaa cct tcc acg ctg gat cat ccc cgc gtg gtg 1603 Gln Pro Arg Glu Leu Glu Pro Ser Thr Leu Asp His Pro Arg Val Val 490 495 500 gag gat ctg cgc aag gga tac cgc gaa tca ggc gac tagctgcaac 1649 Glu Asp Leu Arg Lys Gly Tyr Arg Glu Ser Gly Asp 505 510 gatgcgctgt gtg 1662 <210> 348 <211> 513 <212> PRT <213> Corynebacterium glutamicum <400> 348 Met Ser Asp Leu Gly Pro Ile Trp Arg Trp Leu Leu Leu Val Ser Val 1 5 10 15 Ser Ile Cys Ala Ala Ser Gly Leu Val Tyr Glu Leu Ala Leu Val Ser 20 25 30 Leu Ser Thr Ser Leu Asn Gly Gly Gly Ile Val Glu Thr Ser Leu Ile 35 40 45 Val Ala Gly Tyr Val Ala Ala Leu Gly Leu Gly Ala Leu Leu Val Lys 50 55 60 Pro Phe Leu Asn Trp Pro Ala Gln Thr Phe Leu Gly Val Glu Thr Leu 65 70 75 80 Leu Gly Leu Ile Gly Gly Cys Ser Ala Leu Val Leu Tyr Phe Thr Phe 85 90 95 Ala Thr Ile Gly Gln Ser Leu Trp Ile Leu Val Ile Ala Thr Ala Ala 100 105 110 Ile Gly Ile Leu Val Gly Ala Glu Leu Pro Leu Leu Met Thr Met Ile 115 120 125 Gln Gln Gly Arg Leu Ala Asp Ala Lys Thr Thr Gly Ser Leu Val Ala 130 135 140 Thr Leu Asn Ala Ala Asp Tyr Leu Gly Ala Leu Leu Gly Gly Leu Ala 145 150 155 160 Trp Pro Phe Val Leu Leu Pro Trp Leu Gly Met Met Arg Gly Ala Ala 165 170 175 Ala Ala Gly Met Ile Asn Leu Val Ala Ala Leu Phe Val Gly Cys Val 180 185 190 Leu Leu Arg His Leu Leu Pro Arg Thr His Phe Phe Val Ser Val Val 195 200 205 Ala Leu Leu Leu Ala Ile Ala Ala Leu Ala Thr Val Leu Val Lys Ser 210 215 220 Asp Gly Ile Val Ala Thr Ala Arg Ala Gln Leu Tyr Arg Asp Pro Val 225 230 235 240 Ile Tyr Ser His Gln Ser Asp Tyr Gln Asp Ile Val Val Thr Glu Arg 245 250 255 Gly Lys Asp Arg Arg Leu Tyr Leu Asn Gly Gly Leu Gln Tyr Ser Thr 260 265 270 Arg Asp Gln His Arg Tyr Thr Glu Ser Leu Val Tyr Pro Ser Leu Asn 275 280 285 Pro Glu Ala Glu Ser Val Leu Ile Ile Gly Gly Gly Asp Gly Leu Ala 290 295 300 Ala Arg Glu Leu Leu Arg Phe Pro Ser Met Gln Ile Thr Gln Val Glu 305 310 315 320 Leu Asp Pro Glu Val Ile Glu Val Ala Asn Thr Val Leu Arg Ser Asp 325 330 335 Asn Gly Gly Ala Met Glu Asp Pro Arg Val Ser Ile Ile Val Asp Asp 340 345 350 Ala Phe Thr Trp Leu Arg Ser Gly Gly Asn Asn Gly Glu Thr Tyr Asp 355 360 365 Ser Ile Ile Ile Asp Leu Pro Asp Pro Asn Asn Asp Thr Met Ala Arg 370 375 380 Leu Tyr Ser Glu Glu Phe Tyr Thr Leu Ala Arg Ala Arg Leu Asn Glu 385 390 395 400 Gln Gly Arg Met Val Val Gln Ser Ser Ser Ala Tyr Thr Thr Pro Asp 405 410 415 Val Phe Trp Arg Val Gly Ala Thr Leu Lys Ser Ala Gly Cys Glu Gln 420 425 430 Val Ile Pro Tyr His Val His Val Pro Thr Phe Gly Asp Trp Gly Phe 435 440 445 Gln Leu Cys Gly Pro Ala Asp Met Glu Leu Glu Leu Arg Glu Asp Thr 450 455 460 Pro Pro Leu Thr Phe Leu Asn Asp Glu Val Leu Val Ala Ala Gly Val 465 470 475 480 Phe Gly Leu Asp Asn Gln Pro Arg Glu Leu Glu Pro Ser Thr Leu Asp 485 490 495 His Pro Arg Val Val Glu Asp Leu Arg Lys Gly Tyr Arg Glu Ser Gly 500 505 510 Asp <210> 349 <211> 924 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(901) <223> RXA01757 <400> 349 cgcttattga acggatgcct ctcgatcaag ccaacgaggc tattgcacgt atttcagctg 60 gtaaaccacg tttccgtatt gtcttggagc cgaattcata atg cca aca gca agc 115 Met Pro Thr Ala Ser 1 5 cca att tat gat gtc gtt gtc gtc gga gcc ggc att tct ggc ctc atc 163 Pro Ile Tyr Asp Val Val Val Val Gly Ala Gly Ile Ser Gly Leu Ile 10 15 20 gcc acg caa ctg ttg gac cgc gca ggt cta aac atc aaa tgc ttc gaa 211 Ala Thr Gln Leu Leu Asp Arg Ala Gly Leu Asn Ile Lys Cys Phe Glu 25 30 35 gcc tgc tca aga gtt ggc ggc cga gca gtg tct gtc caa cag tcc gat 259 Ala Cys Ser Arg Val Gly Gly Arg Ala Val Ser Val Gln Gln Ser Asp 40 45 50 ttg ttc ctg gac ctc ggc gca aca tgg ttc tgg ctc aac gaa cca ctt 307 Leu Phe Leu Asp Leu Gly Ala Thr Trp Phe Trp Leu Asn Glu Pro Leu 55 60 65 gtg cag caa ctc gtc aat aat ctc ggc ctc ggc aca ttc cct cag gcc 355 Val Gln Gln Leu Val Asn Asn Leu Gly Leu Gly Thr Phe Pro Gln Ala 70 75 80 85 atc gag ggt gat gcg ctt ttt gag acg ctt gtc gac gcc ccg agc cgc 403 Ile Glu Gly Asp Ala Leu Phe Glu Thr Leu Val Asp Ala Pro Ser Arg 90 95 100 ctg cgg ggt aac ccc ata gac gct gct tca ggc agg ttc caa gca ggg 451 Leu Arg Gly Asn Pro Ile Asp Ala Ala Ser Gly Arg Phe Gln Ala Gly 105 110 115 gcc tcc tcg ctt gcg ctc ggg ctt gca gcc cag ctc aag cca gga gtt 499 Ala Ser Ser Leu Ala Leu Gly Leu Ala Ala Gln Leu Lys Pro Gly Val 120 125 130 tta gaa ctc ggg gac ccc gtc cat tct ctc agt gag gaa gat ggg gaa 547 Leu Glu Leu Gly Asp Pro Val His Ser Leu Ser Glu Glu Asp Gly Glu 135 140 145 atc gtt gtg aag tct tcc aaa cag att gtg agg gca aag cac gtc atc 595 Ile Val Val Lys Ser Ser Lys Gln Ile Val Arg Ala Lys His Val Ile 150 155 160 165 att gcg gtt cca ccg gca ctc gct gcc gag ttg att ggt ttc acc cta 643 Ile Ala Val Pro Pro Ala Leu Ala Ala Glu Leu Ile Gly Phe Thr Leu 170 175 180 gat tta cca gct gac gtg cga aaa gca gcg cat cca caa cat ata gct 691 Asp Leu Pro Ala Asp Val Arg Lys Ala Ala His Pro Gln His Ile Ala 185 190 195 gtg atg aat tgg gca aag gag aaa tac acc tta ccc aca caa gcc gca 739 Val Met Asn Trp Ala Lys Glu Lys Tyr Thr Leu Pro Thr Gln Ala Ala 200 205 210 tcg gct ggg ggt ttt ggg cat gag ctg ttc caa caa cca ctc gga cat 787 Ser Ala Gly Gly Phe Gly His Glu Leu Phe Gln Gln Pro Leu Gly His 215 220 225 ggg cga att cat tgg gca tca acg gaa gtt gcc act gag ttt ggt gga 835 Gly Arg Ile His Trp Ala Ser Thr Glu Val Ala Thr Glu Phe Gly Gly 230 235 240 245 cac ctt gaa ggc gca gtt cgt gca gga att cag gct gcg ctt caa aca 883 His Leu Glu Gly Ala Val Arg Ala Gly Ile Gln Ala Ala Leu Gln Thr 250 255 260 gga ttt aat cta aaa tct taaacctcgt attttccctg ata 924 Gly Phe Asn Leu Lys Ser 265 <210> 350 <211> 267 <212> PRT <213> Corynebacterium glutamicum <400> 350 Met Pro Thr Ala Ser Pro Ile Tyr Asp Val Val Val Val Gly Ala Gly 1 5 10 15 Ile Ser Gly Leu Ile Ala Thr Gln Leu Leu Asp Arg Ala Gly Leu Asn 20 25 30 Ile Lys Cys Phe Glu Ala Cys Ser Arg Val Gly Gly Arg Ala Val Ser 35 40 45 Val Gln Gln Ser Asp Leu Phe Leu Asp Leu Gly Ala Thr Trp Phe Trp 50 55 60 Leu Asn Glu Pro Leu Val Gln Gln Leu Val Asn Asn Leu Gly Leu Gly 65 70 75 80 Thr Phe Pro Gln Ala Ile Glu Gly Asp Ala Leu Phe Glu Thr Leu Val 85 90 95 Asp Ala Pro Ser Arg Leu Arg Gly Asn Pro Ile Asp Ala Ala Ser Gly 100 105 110 Arg Phe Gln Ala Gly Ala Ser Ser Leu Ala Leu Gly Leu Ala Ala Gln 115 120 125 Leu Lys Pro Gly Val Leu Glu Leu Gly Asp Pro Val His Ser Leu Ser 130 135 140 Glu Glu Asp Gly Glu Ile Val Val Lys Ser Ser Lys Gln Ile Val Arg 145 150 155 160 Ala Lys His Val Ile Ile Ala Val Pro Pro Ala Leu Ala Ala Glu Leu 165 170 175 Ile Gly Phe Thr Leu Asp Leu Pro Ala Asp Val Arg Lys Ala Ala His 180 185 190 Pro Gln His Ile Ala Val Met Asn Trp Ala Lys Glu Lys Tyr Thr Leu 195 200 205 Pro Thr Gln Ala Ala Ser Ala Gly Gly Phe Gly His Glu Leu Phe Gln 210 215 220 Gln Pro Leu Gly His Gly Arg Ile His Trp Ala Ser Thr Glu Val Ala 225 230 235 240 Thr Glu Phe Gly Gly His Leu Glu Gly Ala Val Arg Ala Gly Ile Gln 245 250 255 Ala Ala Leu Gln Thr Gly Phe Asn Leu Lys Ser 260 265 <210> 351 <211> 636 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> RXA02159 <400> 351 tgatggacca gcgtccaaag ttttcgatga agcagaaaac cgcctccacg ctcagaaagc 60 actgctggtg tggctgctgg ccaaccagcc gaggtaagac atg tcc ctt ggc tca 115 Met Ser Leu Gly Ser 1 5 acc ccg tca aca ccg gaa aac tta aat ccc gtg act cgc act gca cgc 163 Thr Pro Ser Thr Pro Glu Asn Leu Asn Pro Val Thr Arg Thr Ala Arg 10 15 20 caa gct ctc att ttg cag att ttg gac aaa caa aaa gtc acc agc cag 211 Gln Ala Leu Ile Leu Gln Ile Leu Asp Lys Gln Lys Val Thr Ser Gln 25 30 35 gta caa ctg tct gaa ttg ctg ctg gat gaa ggc atc gat atc acc cag 259 Val Gln Leu Ser Glu Leu Leu Leu Asp Glu Gly Ile Asp Ile Thr Gln 40 45 50 gcc acc ttg tcc cga gat ctc gat gaa ctc ggt gca cgc aag gtt cgc 307 Ala Thr Leu Ser Arg Asp Leu Asp Glu Leu Gly Ala Arg Lys Val Arg 55 60 65 ccc gat ggg gga cgc gcc tac tac gcg gtc ggc cca gta gat agc atc 355 Pro Asp Gly Gly Arg Ala Tyr Tyr Ala Val Gly Pro Val Asp Ser Ile 70 75 80 85 gcc cgc gaa gat ctc cgg ggt ccg tcg gag aag ctg cgc cgc atg ctt 403 Ala Arg Glu Asp Leu Arg Gly Pro Ser Glu Lys Leu Arg Arg Met Leu 90 95 100 gat gaa ctg ctg gtt tct aca gat cat tcc ggc aac atc gcg atg ctg 451 Asp Glu Leu Leu Val Ser Thr Asp His Ser Gly Asn Ile Ala Met Leu 105 110 115 cgc acc ccg ccg gga gct gcc cag tac ctg gca agt ttc atc gat agg 499 Arg Thr Pro Pro Gly Ala Ala Gln Tyr Leu Ala Ser Phe Ile Asp Arg 120 125 130 gtg ggg ctg aaa gaa gtc gtt ggc acc atc gct ggt gat gac acc gtt 547 Val Gly Leu Lys Glu Val Val Gly Thr Ile Ala Gly Asp Asp Thr Val 135 140 145 ttc gtt ctc gcc cgt gat ccg ctc aca ggt aaa gaa cta ggt gaa tta 595 Phe Val Leu Ala Arg Asp Pro Leu Thr Gly Lys Glu Leu Gly Glu Leu 150 155 160 165 ctc agc ggg cgc acc act taaagcgccc ctagttcaag gct 636 Leu Ser Gly Arg Thr Thr 170 <210> 352 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 352 Met Ser Leu Gly Ser Thr Pro Ser Thr Pro Glu Asn Leu Asn Pro Val 1 5 10 15 Thr Arg Thr Ala Arg Gln Ala Leu Ile Leu Gln Ile Leu Asp Lys Gln 20 25 30 Lys Val Thr Ser Gln Val Gln Leu Ser Glu Leu Leu Leu Asp Glu Gly 35 40 45 Ile Asp Ile Thr Gln Ala Thr Leu Ser Arg Asp Leu Asp Glu Leu Gly 50 55 60 Ala Arg Lys Val Arg Pro Asp Gly Gly Arg Ala Tyr Tyr Ala Val Gly 65 70 75 80 Pro Val Asp Ser Ile Ala Arg Glu Asp Leu Arg Gly Pro Ser Glu Lys 85 90 95 Leu Arg Arg Met Leu Asp Glu Leu Leu Val Ser Thr Asp His Ser Gly 100 105 110 Asn Ile Ala Met Leu Arg Thr Pro Pro Gly Ala Ala Gln Tyr Leu Ala 115 120 125 Ser Phe Ile Asp Arg Val Gly Leu Lys Glu Val Val Gly Thr Ile Ala 130 135 140 Gly Asp Asp Thr Val Phe Val Leu Ala Arg Asp Pro Leu Thr Gly Lys 145 150 155 160 Glu Leu Gly Glu Leu Leu Ser Gly Arg Thr Thr 165 170 <210> 353 <211> 414 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(391) <223> RXN02154 <400> 353 cccagaacct cggcgaagtc agcgacaagc cagtcaaggt gagcttcacc ccagtgcttg 60 caccgttacc tcgcgaattc tcaccactgc aaccgcacct ttg aaa gaa ggc gtt 115 Leu Lys Glu Gly Val 1 5 acc gca gaa cag gct cgc gca gta tat gaa gag ttc tat gca cag gaa 163 Thr Ala Glu Gln Ala Arg Ala Val Tyr Glu Glu Phe Tyr Ala Gln Glu 10 15 20 acc ttc gtg cat gtt ctt cca gaa ggt gca cag cca caa acc caa gca 211 Thr Phe Val His Val Leu Pro Glu Gly Ala Gln Pro Gln Thr Gln Ala 25 30 35 gtt ctt ggc tcc aac atg tgc cac gtg cag gta gaa att gat gag gaa 259 Val Leu Gly Ser Asn Met Cys His Val Gln Val Glu Ile Asp Glu Glu 40 45 50 gca ggc aaa gtc ctt gtt acc tcc gca atc gat aac ctc acc aag gga 307 Ala Gly Lys Val Leu Val Thr Ser Ala Ile Asp Asn Leu Thr Lys Gly 55 60 65 act gcc ggc gcc gct gtt cag tgc atg aac tta agc gtt ggt ttt gat 355 Thr Ala Gly Ala Ala Val Gln Cys Met Asn Leu Ser Val Gly Phe Asp 70 75 80 85 gag gca gca ggc ctg cca cag gtc ggc gtc gca cct taaagtagcg 401 Glu Ala Ala Gly Leu Pro Gln Val Gly Val Ala Pro 90 95 ccttaaagcg gcg 414 <210> 354 <211> 97 <212> PRT <213> Corynebacterium glutamicum <400> 354 Leu Lys Glu Gly Val Thr Ala Glu Gln Ala Arg Ala Val Tyr Glu Glu 1 5 10 15 Phe Tyr Ala Gln Glu Thr Phe Val His Val Leu Pro Glu Gly Ala Gln 20 25 30 Pro Gln Thr Gln Ala Val Leu Gly Ser Asn Met Cys His Val Gln Val 35 40 45 Glu Ile Asp Glu Glu Ala Gly Lys Val Leu Val Thr Ser Ala Ile Asp 50 55 60 Asn Leu Thr Lys Gly Thr Ala Gly Ala Ala Val Gln Cys Met Asn Leu 65 70 75 80 Ser Val Gly Phe Asp Glu Ala Ala Gly Leu Pro Gln Val Gly Val Ala 85 90 95 Pro <210> 355 <211> 1302 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1279) <223> RXS00147 <400> 355 attgcatata atgcaatgaa ttgaataaac tacattcagg gttatcaacc agccaatttc 60 ttttaaaaag gcagacacac gaaaggcgac aacagtcacc gtg agt aaa gac acc 115 Val Ser Lys Asp Thr 1 5 acc acc tac cag gga gtc acc gag atc gga tcc gtt ccg gca tac ctg 163 Thr Thr Tyr Gln Gly Val Thr Glu Ile Gly Ser Val Pro Ala Tyr Leu 10 15 20 gtt ctt gca gac gga cgt acc ttc acc gga ttt ggc ttt gga gct atc 211 Val Leu Ala Asp Gly Arg Thr Phe Thr Gly Phe Gly Phe Gly Ala Ile 25 30 35 ggc acc acc ctt ggt gag gca gtg ttc act acc gcc atg acc ggt tac 259 Gly Thr Thr Leu Gly Glu Ala Val Phe Thr Thr Ala Met Thr Gly Tyr 40 45 50 caa gaa acc atg acc gat cct tcc tat cac cgc cag att gtt gtg gct 307 Gln Glu Thr Met Thr Asp Pro Ser Tyr His Arg Gln Ile Val Val Ala 55 60 65 acc gca cca cag atc ggc aac acc ggc tgg aac gat gag gac aac gag 355 Thr Ala Pro Gln Ile Gly Asn Thr Gly Trp Asn Asp Glu Asp Asn Glu 70 75 80 85 tcc cgc gac ggc aag att tgg gtt gca ggc ctt gtt atc cgc gac ctc 403 Ser Arg Asp Gly Lys Ile Trp Val Ala Gly Leu Val Ile Arg Asp Leu 90 95 100 gca gca cgt gtg tcc aac tgg cgc gcc acc acc tcc ttg cag cag gaa 451 Ala Ala Arg Val Ser Asn Trp Arg Ala Thr Thr Ser Leu Gln Gln Glu 105 110 115 atg gca ggc cag ggc atc gtc ggc atc ggc gga atc gac acc cgc gca 499 Met Ala Gly Gln Gly Ile Val Gly Ile Gly Gly Ile Asp Thr Arg Ala 120 125 130 ctg gtt cgc cac ctg cgc aat gaa ggt tcc att gca gcg ggc atc ttc 547 Leu Val Arg His Leu Arg Asn Glu Gly Ser Ile Ala Ala Gly Ile Phe 135 140 145 tcc ggc gct gac gca cag cgc cca gtt gaa gaa ctc gta gag atc gtc 595 Ser Gly Ala Asp Ala Gln Arg Pro Val Glu Glu Leu Val Glu Ile Val 150 155 160 165 aag aat cag cca gca atg acc ggc gca aac ctc tcc gtt gag gtc tct 643 Lys Asn Gln Pro Ala Met Thr Gly Ala Asn Leu Ser Val Glu Val Ser 170 175 180 gct gat gaa acc tac gtc atc gaa gct gaa ggc gaa gag cgc cac acc 691 Ala Asp Glu Thr Tyr Val Ile Glu Ala Glu Gly Glu Glu Arg His Thr 185 190 195 gtc gtg gcc tac gac ctg ggc att aag caa aac acc cca cgt cgt ttc 739 Val Val Ala Tyr Asp Leu Gly Ile Lys Gln Asn Thr Pro Arg Arg Phe 200 205 210 tct gca cgc ggt gtt cgc acc gtc atc gtg cct gct gaa acc cca ttc 787 Ser Ala Arg Gly Val Arg Thr Val Ile Val Pro Ala Glu Thr Pro Phe 215 220 225 gag gat atc aag cag tac aac cca tca ggc gtg ttc atc tcc aac ggc 835 Glu Asp Ile Lys Gln Tyr Asn Pro Ser Gly Val Phe Ile Ser Asn Gly 230 235 240 245 cct ggc gat cct gca gca gca gac gtc atg gtt gat atc gtc cgc gaa 883 Pro Gly Asp Pro Ala Ala Ala Asp Val Met Val Asp Ile Val Arg Glu 250 255 260 gtt ctt gaa gcc gac att cca ttc ttt ggc atc tgc ttc ggc aac cag 931 Val Leu Glu Ala Asp Ile Pro Phe Phe Gly Ile Cys Phe Gly Asn Gln 265 270 275 att ctt ggc cgc gca ttc ggc atg gag acc tac aag ctg aag ttc ggc 979 Ile Leu Gly Arg Ala Phe Gly Met Glu Thr Tyr Lys Leu Lys Phe Gly 280 285 290 cac cgc ggc atc aac gtt cca gtg aag aac cac atc acc ggc aag atc 1027 His Arg Gly Ile Asn Val Pro Val Lys Asn His Ile Thr Gly Lys Ile 295 300 305 gac atc acc gcc cag aac cac ggc ttc gca ctc aag ggt gaa gca ggc 1075 Asp Ile Thr Ala Gln Asn His Gly Phe Ala Leu Lys Gly Glu Ala Gly 310 315 320 325 cag gaa ttc gag acc gat ttc ggc act gca att gtc acc cac acc tgc 1123 Gln Glu Phe Glu Thr Asp Phe Gly Thr Ala Ile Val Thr His Thr Cys 330 335 340 ctc aac gac ggc gtc gtt gaa ggt att gcg ctg aag tcc gga cgc gca 1171 Leu Asn Asp Gly Val Val Glu Gly Ile Ala Leu Lys Ser Gly Arg Ala 345 350 355 tac tcc gtt cag tac cac cca gag gcc gct gcc ggc cca aat gat gca 1219 Tyr Ser Val Gln Tyr His Pro Glu Ala Ala Ala Gly Pro Asn Asp Ala 360 365 370 agc ccc ctg ttt gac cag ttt gtt gag ctg atg gat gca gac gct cag 1267 Ser Pro Leu Phe Asp Gln Phe Val Glu Leu Met Asp Ala Asp Ala Gln 375 380 385 aag aaa ggc gca taaataacat gccaaagcgt tca 1302 Lys Lys Gly Ala 390 <210> 356 <211> 393 <212> PRT <213> Corynebacterium glutamicum <400> 356 Val Ser Lys Asp Thr Thr Thr Tyr Gln Gly Val Thr Glu Ile Gly Ser 1 5 10 15 Val Pro Ala Tyr Leu Val Leu Ala Asp Gly Arg Thr Phe Thr Gly Phe 20 25 30 Gly Phe Gly Ala Ile Gly Thr Thr Leu Gly Glu Ala Val Phe Thr Thr 35 40 45 Ala Met Thr Gly Tyr Gln Glu Thr Met Thr Asp Pro Ser Tyr His Arg 50 55 60 Gln Ile Val Val Ala Thr Ala Pro Gln Ile Gly Asn Thr Gly Trp Asn 65 70 75 80 Asp Glu Asp Asn Glu Ser Arg Asp Gly Lys Ile Trp Val Ala Gly Leu 85 90 95 Val Ile Arg Asp Leu Ala Ala Arg Val Ser Asn Trp Arg Ala Thr Thr 100 105 110 Ser Leu Gln Gln Glu Met Ala Gly Gln Gly Ile Val Gly Ile Gly Gly 115 120 125 Ile Asp Thr Arg Ala Leu Val Arg His Leu Arg Asn Glu Gly Ser Ile 130 135 140 Ala Ala Gly Ile Phe Ser Gly Ala Asp Ala Gln Arg Pro Val Glu Glu 145 150 155 160 Leu Val Glu Ile Val Lys Asn Gln Pro Ala Met Thr Gly Ala Asn Leu 165 170 175 Ser Val Glu Val Ser Ala Asp Glu Thr Tyr Val Ile Glu Ala Glu Gly 180 185 190 Glu Glu Arg His Thr Val Val Ala Tyr Asp Leu Gly Ile Lys Gln Asn 195 200 205 Thr Pro Arg Arg Phe Ser Ala Arg Gly Val Arg Thr Val Ile Val Pro 210 215 220 Ala Glu Thr Pro Phe Glu Asp Ile Lys Gln Tyr Asn Pro Ser Gly Val 225 230 235 240 Phe Ile Ser Asn Gly Pro Gly Asp Pro Ala Ala Ala Asp Val Met Val 245 250 255 Asp Ile Val Arg Glu Val Leu Glu Ala Asp Ile Pro Phe Phe Gly Ile 260 265 270 Cys Phe Gly Asn Gln Ile Leu Gly Arg Ala Phe Gly Met Glu Thr Tyr 275 280 285 Lys Leu Lys Phe Gly His Arg Gly Ile Asn Val Pro Val Lys Asn His 290 295 300 Ile Thr Gly Lys Ile Asp Ile Thr Ala Gln Asn His Gly Phe Ala Leu 305 310 315 320 Lys Gly Glu Ala Gly Gln Glu Phe Glu Thr Asp Phe Gly Thr Ala Ile 325 330 335 Val Thr His Thr Cys Leu Asn Asp Gly Val Val Glu Gly Ile Ala Leu 340 345 350 Lys Ser Gly Arg Ala Tyr Ser Val Gln Tyr His Pro Glu Ala Ala Ala 355 360 365 Gly Pro Asn Asp Ala Ser Pro Leu Phe Asp Gln Phe Val Glu Leu Met 370 375 380 Asp Ala Asp Ala Gln Lys Lys Gly Ala 385 390 <210> 357 <211> 924 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(901) <223> RXS00905 <400> 357 cgctgcccct ctatgctgct cctagttacc cctgcacaaa tagcggtttt tctcacgcat 60 tctgcatcga gtcgggtcga cgtatataag gtggaaaggc atg acc caa ttc gaa 115 Met Thr Gln Phe Glu 1 5 aac gcg caa gta ctt aaa gag aac atc gaa aac caa cgc gag cag atc 163 Asn Ala Gln Val Leu Lys Glu Asn Ile Glu Asn Gln Arg Glu Gln Ile 10 15 20 ttt acc cag ttg aaa gaa att gtg tct ttc aac tcc gtg cac agc gat 211 Phe Thr Gln Leu Lys Glu Ile Val Ser Phe Asn Ser Val His Ser Asp 25 30 35 cca aac cta ctg gag gac tac gcc ggc gcg aaa gaa tgg gta aaa gaa 259 Pro Asn Leu Leu Glu Asp Tyr Ala Gly Ala Lys Glu Trp Val Lys Glu 40 45 50 aca ctg acc aac gca ggt ctc acc gtc agc gaa ttc gct gcc gaa gat 307 Thr Leu Thr Asn Ala Gly Leu Thr Val Ser Glu Phe Ala Ala Glu Asp 55 60 65 gga acc acc aac ttc atc ggc acc cgc aag ggc tcc gaa ggt gca cca 355 Gly Thr Thr Asn Phe Ile Gly Thr Arg Lys Gly Ser Glu Gly Ala Pro 70 75 80 85 aag gta ctg ctg tac agc cac ttc gac gtt gtc cca tcc ggc cct ttg 403 Lys Val Leu Leu Tyr Ser His Phe Asp Val Val Pro Ser Gly Pro Leu 90 95 100 gat ctc tgg gac acc aat cct ttt gaa ctc acc gag cgc gac gct ggc 451 Asp Leu Trp Asp Thr Asn Pro Phe Glu Leu Thr Glu Arg Asp Ala Gly 105 110 115 cac ggc acc cgc tgg tac ggc cgc ggc gcc gct gac tgc aag ggc aac 499 His Gly Thr Arg Trp Tyr Gly Arg Gly Ala Ala Asp Cys Lys Gly Asn 120 125 130 ctg gtc atg cac ctc gca gca ctg cgc gcc gtc gaa gcc agc ggc gac 547 Leu Val Met His Leu Ala Ala Leu Arg Ala Val Glu Ala Ser Gly Asp 135 140 145 acc aca ctc aac ctc acc tac gtg gtc gag ggc tcc gag gaa atg gga 595 Thr Thr Leu Asn Leu Thr Tyr Val Val Glu Gly Ser Glu Glu Met Gly 150 155 160 165 ggc gga gcg ctc agc gcg ctc atc aag gac aag cct gag ctt ttc gac 643 Gly Gly Ala Leu Ser Ala Leu Ile Lys Asp Lys Pro Glu Leu Phe Asp 170 175 180 gca gat gtc atc ttg att gca gac agc gga aac gct tcc gtg ggc acc 691 Ala Asp Val Ile Leu Ile Ala Asp Ser Gly Asn Ala Ser Val Gly Thr 185 190 195 cca acc ttg acc act acc ctg cgc ggt ggc gga cag gtc acc gtc acc 739 Pro Thr Leu Thr Thr Thr Leu Arg Gly Gly Gly Gln Val Thr Val Thr 200 205 210 gtg gac acc ctt gaa ggc gct gtt cac tcc ggc cag aac ggt ggc gct 787 Val Asp Thr Leu Glu Gly Ala Val His Ser Gly Gln Asn Gly Gly Ala 215 220 225 gcc cca gat gct gtt gct gct ctc gtg cgc gtt ctg gat act ttg cgc 835 Ala Pro Asp Ala Val Ala Ala Leu Val Arg Val Leu Asp Thr Leu Arg 230 235 240 245 gat gaa cac gga cgc acc gtt atc gac ggc tgt caa cac cac cgc aaa 883 Asp Glu His Gly Arg Thr Val Ile Asp Gly Cys Gln His His Arg Lys 250 255 260 ctg gaa ggg cga gcc tta tgatccagag actttccgca gcg 924 Leu Glu Gly Arg Ala Leu 265 <210> 358 <211> 267 <212> PRT <213> Corynebacterium glutamicum <400> 358 Met Thr Gln Phe Glu Asn Ala Gln Val Leu Lys Glu Asn Ile Glu Asn 1 5 10 15 Gln Arg Glu Gln Ile Phe Thr Gln Leu Lys Glu Ile Val Ser Phe Asn 20 25 30 Ser Val His Ser Asp Pro Asn Leu Leu Glu Asp Tyr Ala Gly Ala Lys 35 40 45 Glu Trp Val Lys Glu Thr Leu Thr Asn Ala Gly Leu Thr Val Ser Glu 50 55 60 Phe Ala Ala Glu Asp Gly Thr Thr Asn Phe Ile Gly Thr Arg Lys Gly 65 70 75 80 Ser Glu Gly Ala Pro Lys Val Leu Leu Tyr Ser His Phe Asp Val Val 85 90 95 Pro Ser Gly Pro Leu Asp Leu Trp Asp Thr Asn Pro Phe Glu Leu Thr 100 105 110 Glu Arg Asp Ala Gly His Gly Thr Arg Trp Tyr Gly Arg Gly Ala Ala 115 120 125 Asp Cys Lys Gly Asn Leu Val Met His Leu Ala Ala Leu Arg Ala Val 130 135 140 Glu Ala Ser Gly Asp Thr Thr Leu Asn Leu Thr Tyr Val Val Glu Gly 145 150 155 160 Ser Glu Glu Met Gly Gly Gly Ala Leu Ser Ala Leu Ile Lys Asp Lys 165 170 175 Pro Glu Leu Phe Asp Ala Asp Val Ile Leu Ile Ala Asp Ser Gly Asn 180 185 190 Ala Ser Val Gly Thr Pro Thr Leu Thr Thr Thr Leu Arg Gly Gly Gly 195 200 205 Gln Val Thr Val Thr Val Asp Thr Leu Glu Gly Ala Val His Ser Gly 210 215 220 Gln Asn Gly Gly Ala Ala Pro Asp Ala Val Ala Ala Leu Val Arg Val 225 230 235 240 Leu Asp Thr Leu Arg Asp Glu His Gly Arg Thr Val Ile Asp Gly Cys 245 250 255 Gln His His Arg Lys Leu Glu Gly Arg Ala Leu 260 265 <210> 359 <211> 627 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(604) <223> RXS00906 <400> 359 accgtggaca cccttgaagg cgctgttcac tccggccaga acggtggcgc tgccccagat 60 gctgttgctg ctctcgtgcg cgttctggat actttgcgcg atg aac acg gac gca 115 Met Asn Thr Asp Ala 1 5 ccg tta tcg acg gct gtc aac acc acc gca aac tgg aag ggc gag cct 163 Pro Leu Ser Thr Ala Val Asn Thr Thr Ala Asn Trp Lys Gly Glu Pro 10 15 20 tat gat cca gag act ttc cgc agc gat gcc ggc atc ctc gac ggt gta 211 Tyr Asp Pro Glu Thr Phe Arg Ser Asp Ala Gly Ile Leu Asp Gly Val 25 30 35 gac atc atg ggc gac ggc gac aac cca gca agc atg ctg tgg tcc agg 259 Asp Ile Met Gly Asp Gly Asp Asn Pro Ala Ser Met Leu Trp Ser Arg 40 45 50 cct gca atc tcc atc acc gga ttc act tcc acc cca gtg gca gaa gca 307 Pro Ala Ile Ser Ile Thr Gly Phe Thr Ser Thr Pro Val Ala Glu Ala 55 60 65 ctc aac gca gtg ccc gca acg gcg tcc gcc aag cta aac ctt cgc gtg 355 Leu Asn Ala Val Pro Ala Thr Ala Ser Ala Lys Leu Asn Leu Arg Val 70 75 80 85 cca gca ggc ctg gaa gca aac gat gtg gcc gag aag ctg aag cag cac 403 Pro Ala Gly Leu Glu Ala Asn Asp Val Ala Glu Lys Leu Lys Gln His 90 95 100 ctg atc aat cac aca cct tgg ggc gca aag atc acg gtg gag atc gat 451 Leu Ile Asn His Thr Pro Trp Gly Ala Lys Ile Thr Val Glu Ile Asp 105 110 115 gac att aac caa ccg ttc tcc acc gat att acc ggc cct gca atg tcc 499 Asp Ile Asn Gln Pro Phe Ser Thr Asp Ile Thr Gly Pro Ala Met Ser 120 125 130 acc ctg gcg tcc tgc ctg agc gct gcg tac gag ggc aag gat ctt gtc 547 Thr Leu Ala Ser Cys Leu Ser Ala Ala Tyr Glu Gly Lys Asp Leu Val 135 140 145 acc gaa ggc agc ggc gga tcc att cca ctg tgt acc gaa ctg att gag 595 Thr Glu Gly Ser Gly Gly Ser Ile Pro Leu Cys Thr Glu Leu Ile Glu 150 155 160 165 gtc aac cca taagcagaat tggcactcta cgg 627 Val Asn Pro <210> 360 <211> 168 <212> PRT <213> Corynebacterium glutamicum <400> 360 Met Asn Thr Asp Ala Pro Leu Ser Thr Ala Val Asn Thr Thr Ala Asn 1 5 10 15 Trp Lys Gly Glu Pro Tyr Asp Pro Glu Thr Phe Arg Ser Asp Ala Gly 20 25 30 Ile Leu Asp Gly Val Asp Ile Met Gly Asp Gly Asp Asn Pro Ala Ser 35 40 45 Met Leu Trp Ser Arg Pro Ala Ile Ser Ile Thr Gly Phe Thr Ser Thr 50 55 60 Pro Val Ala Glu Ala Leu Asn Ala Val Pro Ala Thr Ala Ser Ala Lys 65 70 75 80 Leu Asn Leu Arg Val Pro Ala Gly Leu Glu Ala Asn Asp Val Ala Glu 85 90 95 Lys Leu Lys Gln His Leu Ile Asn His Thr Pro Trp Gly Ala Lys Ile 100 105 110 Thr Val Glu Ile Asp Asp Ile Asn Gln Pro Phe Ser Thr Asp Ile Thr 115 120 125 Gly Pro Ala Met Ser Thr Leu Ala Ser Cys Leu Ser Ala Ala Tyr Glu 130 135 140 Gly Lys Asp Leu Val Thr Glu Gly Ser Gly Gly Ser Ile Pro Leu Cys 145 150 155 160 Thr Glu Leu Ile Glu Val Asn Pro 165 <210> 361 <211> 246 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(223) <223> RXS00907 <400> 361 cctgagcgct gcgtacgagg gcaaggatct tgtcaccgaa ggcagcggcg gatccattcc 60 actgtgtacc gaactgattg aggtcaaccc ataagcagaa ttg gca ctc tac ggt 115 Leu Ala Leu Tyr Gly 1 5 gtg gaa gaa ccc ctc acc gtt atc cac tcc gct aat gaa tct gtt gac 163 Val Glu Glu Pro Leu Thr Val Ile His Ser Ala Asn Glu Ser Val Asp 10 15 20 ccc aat gag att cgc gat atc gcc acc gca gaa gca ttg ttc ctg ctc 211 Pro Asn Glu Ile Arg Asp Ile Ala Thr Ala Glu Ala Leu Phe Leu Leu 25 30 35 aac tac acc aag tagacccaaa agcaggcgtt aac 246 Asn Tyr Thr Lys 40 <210> 362 <211> 41 <212> PRT <213> Corynebacterium glutamicum <400> 362 Leu Ala Leu Tyr Gly Val Glu Glu Pro Leu Thr Val Ile His Ser Ala 1 5 10 15 Asn Glu Ser Val Asp Pro Asn Glu Ile Arg Asp Ile Ala Thr Ala Glu 20 25 30 Ala Leu Phe Leu Leu Asn Tyr Thr Lys 35 40 <210> 363 <211> 1281 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1258) <223> RXS02001 <400> 363 gcggtttcgt catggataag gactgtgttc gggaccattg cgatactcgt gtcaaaaggc 60 gatagtccag catagaccgt gctttatcga aggtgaaccc atg ccc gtt atc aat 115 Met Pro Val Ile Asn 1 5 agt atc gcc agt ttt tcc gac gag atg acc cgc tgg cgg cgt cac ctg 163 Ser Ile Ala Ser Phe Ser Asp Glu Met Thr Arg Trp Arg Arg His Leu 10 15 20 cat caa aac ccc gaa atc agc ttt gat tgt gtg gaa act gcg gcc ttc 211 His Gln Asn Pro Glu Ile Ser Phe Asp Cys Val Glu Thr Ala Ala Phe 25 30 35 gtg gcc gag cag ctg cgc agc ttc ggg gtg gat gaa att cac acc ggc 259 Val Ala Glu Gln Leu Arg Ser Phe Gly Val Asp Glu Ile His Thr Gly 40 45 50 atc gcg aaa acc ggt atc atc gcc ctg att cac ggg cgc gag gct ggc 307 Ile Ala Lys Thr Gly Ile Ile Ala Leu Ile His Gly Arg Glu Ala Gly 55 60 65 ccc gtc gtc ggc ctg cgc gcc gat atg gac gcg ctg ccg ctg acc gag 355 Pro Val Val Gly Leu Arg Ala Asp Met Asp Ala Leu Pro Leu Thr Glu 70 75 80 85 att acc ggc gtc gac tat gcc tcg acc acc ccc gga aaa atg cac gcc 403 Ile Thr Gly Val Asp Tyr Ala Ser Thr Thr Pro Gly Lys Met His Ala 90 95 100 tgc ggc cac gac ggc cac acg acc atg ctg ctg ggc gcc gcc aaa tat 451 Cys Gly His Asp Gly His Thr Thr Met Leu Leu Gly Ala Ala Lys Tyr 105 110 115 ctg gcc gag acg cgc aat ttc gca ggt acc gtc gcg ctg atc ttc cag 499 Leu Ala Glu Thr Arg Asn Phe Ala Gly Thr Val Ala Leu Ile Phe Gln 120 125 130 cct gcg gaa gaa aac ggc ggc ggc gcg ggc gtt atg gtc gat gaa ggc 547 Pro Ala Glu Glu Asn Gly Gly Gly Ala Gly Val Met Val Asp Glu Gly 135 140 145 gtc ctc gac cgc ttt gcc atc gcc gaa gtc tac gcc ctg cac aac cag 595 Val Leu Asp Arg Phe Ala Ile Ala Glu Val Tyr Ala Leu His Asn Gln 150 155 160 165 ccc ggc ctg ccg ctt ggc cat ttt atg acg aca gcc ggc ccg atc atg 643 Pro Gly Leu Pro Leu Gly His Phe Met Thr Thr Ala Gly Pro Ile Met 170 175 180 gcc gct gtc gac acg ttc gac atc aac att acc gga cgc ggc ggc cac 691 Ala Ala Val Asp Thr Phe Asp Ile Asn Ile Thr Gly Arg Gly Gly His 185 190 195 ggt gcc aaa ccg cac caa acc cgc gac ccc atc gtc gca gcc gtc gga 739 Gly Ala Lys Pro His Gln Thr Arg Asp Pro Ile Val Ala Ala Val Gly 200 205 210 att gtc caa gcg ttt caa acg ata gtc agc cgg aat cac aat ccg gtc 787 Ile Val Gln Ala Phe Gln Thr Ile Val Ser Arg Asn His Asn Pro Val 215 220 225 gag gac ctt gtc gtg tcg gtc acg caa atc cac acc ggc agc gcc gat 835 Glu Asp Leu Val Val Ser Val Thr Gln Ile His Thr Gly Ser Ala Asp 230 235 240 245 aat atc atc ccc gaa acc gcc tat atc aac ggc act gtc cgc acc ttc 883 Asn Ile Ile Pro Glu Thr Ala Tyr Ile Asn Gly Thr Val Arg Thr Phe 250 255 260 aac aaa gac gtg cag gcc atg gtc atc acg cgg atg gaa gaa atc gtc 931 Asn Lys Asp Val Gln Ala Met Val Ile Thr Arg Met Glu Glu Ile Val 265 270 275 gcg ggc caa gct gca gcc tat ggg gtc gag gcg acg ctg acc tac aac 979 Ala Gly Gln Ala Ala Ala Tyr Gly Val Glu Ala Thr Leu Thr Tyr Asn 280 285 290 cgc aac tat ccc gcc acc att aac gac gcc gcc aaa gcc gcc atc gct 1027 Arg Asn Tyr Pro Ala Thr Ile Asn Asp Ala Ala Lys Ala Ala Ile Ala 295 300 305 gcc gaa gtc gcg ggc gag gtc ggc ctc ggg gtc aac ccg aac ggc tcg 1075 Ala Glu Val Ala Gly Glu Val Gly Leu Gly Val Asn Pro Asn Gly Ser 310 315 320 325 cgc ggg atg ggg gcc gag gat ttc tcg tat ttc ctc gaa aag cgc ccg 1123 Arg Gly Met Gly Ala Glu Asp Phe Ser Tyr Phe Leu Glu Lys Arg Pro 330 335 340 ggt gcc tac ctg ttc gtc ggt aat ggc gac agc gcg ggc ctt cac aac 1171 Gly Ala Tyr Leu Phe Val Gly Asn Gly Asp Ser Ala Gly Leu His Asn 345 350 355 ccc gcc tat aat ttc aac gac gag gcc gcg ccc tac ggc gca tcg ttc 1219 Pro Ala Tyr Asn Phe Asn Asp Glu Ala Ala Pro Tyr Gly Ala Ser Phe 360 365 370 ttg gcc cgc atg gca gaa cgc ccc ttg ccg tta aag ggc tgatccatgg 1268 Leu Ala Arg Met Ala Glu Arg Pro Leu Pro Leu Lys Gly 375 380 385 cgctcgaaga tgc 1281 <210> 364 <211> 386 <212> PRT <213> Corynebacterium glutamicum <400> 364 Met Pro Val Ile Asn Ser Ile Ala Ser Phe Ser Asp Glu Met Thr Arg 1 5 10 15 Trp Arg Arg His Leu His Gln Asn Pro Glu Ile Ser Phe Asp Cys Val 20 25 30 Glu Thr Ala Ala Phe Val Ala Glu Gln Leu Arg Ser Phe Gly Val Asp 35 40 45 Glu Ile His Thr Gly Ile Ala Lys Thr Gly Ile Ile Ala Leu Ile His 50 55 60 Gly Arg Glu Ala Gly Pro Val Val Gly Leu Arg Ala Asp Met Asp Ala 65 70 75 80 Leu Pro Leu Thr Glu Ile Thr Gly Val Asp Tyr Ala Ser Thr Thr Pro 85 90 95 Gly Lys Met His Ala Cys Gly His Asp Gly His Thr Thr Met Leu Leu 100 105 110 Gly Ala Ala Lys Tyr Leu Ala Glu Thr Arg Asn Phe Ala Gly Thr Val 115 120 125 Ala Leu Ile Phe Gln Pro Ala Glu Glu Asn Gly Gly Gly Ala Gly Val 130 135 140 Met Val Asp Glu Gly Val Leu Asp Arg Phe Ala Ile Ala Glu Val Tyr 145 150 155 160 Ala Leu His Asn Gln Pro Gly Leu Pro Leu Gly His Phe Met Thr Thr 165 170 175 Ala Gly Pro Ile Met Ala Ala Val Asp Thr Phe Asp Ile Asn Ile Thr 180 185 190 Gly Arg Gly Gly His Gly Ala Lys Pro His Gln Thr Arg Asp Pro Ile 195 200 205 Val Ala Ala Val Gly Ile Val Gln Ala Phe Gln Thr Ile Val Ser Arg 210 215 220 Asn His Asn Pro Val Glu Asp Leu Val Val Ser Val Thr Gln Ile His 225 230 235 240 Thr Gly Ser Ala Asp Asn Ile Ile Pro Glu Thr Ala Tyr Ile Asn Gly 245 250 255 Thr Val Arg Thr Phe Asn Lys Asp Val Gln Ala Met Val Ile Thr Arg 260 265 270 Met Glu Glu Ile Val Ala Gly Gln Ala Ala Ala Tyr Gly Val Glu Ala 275 280 285 Thr Leu Thr Tyr Asn Arg Asn Tyr Pro Ala Thr Ile Asn Asp Ala Ala 290 295 300 Lys Ala Ala Ile Ala Ala Glu Val Ala Gly Glu Val Gly Leu Gly Val 305 310 315 320 Asn Pro Asn Gly Ser Arg Gly Met Gly Ala Glu Asp Phe Ser Tyr Phe 325 330 335 Leu Glu Lys Arg Pro Gly Ala Tyr Leu Phe Val Gly Asn Gly Asp Ser 340 345 350 Ala Gly Leu His Asn Pro Ala Tyr Asn Phe Asn Asp Glu Ala Ala Pro 355 360 365 Tyr Gly Ala Ser Phe Leu Ala Arg Met Ala Glu Arg Pro Leu Pro Leu 370 375 380 Lys Gly 385 <210> 365 <211> 1386 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1363) <223> RXS02101 <400> 365 gccatggaat gctccgttga acgcaacagc cttaaataca atcccctcct ataagccaag 60 agttttagtg tcgctgcgca ggtactctac tatctaatcc atg agc cgc att tca 115 Met Ser Arg Ile Ser 1 5 gaa ctt cta aac aat cat ggt gtt gat ctg tcg tgg caa gag gcc gca 163 Glu Leu Leu Asn Asn His Gly Val Asp Leu Ser Trp Gln Glu Ala Ala 10 15 20 tat cag gat ttc cac gaa cat cct gag ctc tcc ggc ttc gaa tca gag 211 Tyr Gln Asp Phe His Glu His Pro Glu Leu Ser Gly Phe Glu Ser Glu 25 30 35 acc gca gat cgc att cag aaa tac ctc gag cgt ttt gat tgt gag gtg 259 Thr Ala Asp Arg Ile Gln Lys Tyr Leu Glu Arg Phe Asp Cys Glu Val 40 45 50 att cca aat gtt ggc ggt tac ggc att ctg gcc gtg ttc cga aat ggg 307 Ile Pro Asn Val Gly Gly Tyr Gly Ile Leu Ala Val Phe Arg Asn Gly 55 60 65 tcg aca gat cct ggt gcc cct gtt gcg tta atg cgc gca gat ttc gat 355 Ser Thr Asp Pro Gly Ala Pro Val Ala Leu Met Arg Ala Asp Phe Asp 70 75 80 85 ggc ctt ccc gtc aag gaa atc acc gga gtt ccg ttt gct tcc act cgt 403 Gly Leu Pro Val Lys Glu Ile Thr Gly Val Pro Phe Ala Ser Thr Arg 90 95 100 atg cgt ccg cat gat ggg gca aat gtc cat gtc atg cac gca tgc ggc 451 Met Arg Pro His Asp Gly Ala Asn Val His Val Met His Ala Cys Gly 105 110 115 cac gat gtc cac gtc acc gcg ctg ctt ggt gcg tgt gcc att tta gat 499 His Asp Val His Val Thr Ala Leu Leu Gly Ala Cys Ala Ile Leu Asp 120 125 130 gag cgt cgc gat gca tgg gaa ggc acg ttc atc gcg ttg ttc cag cca 547 Glu Arg Arg Asp Ala Trp Glu Gly Thr Phe Ile Ala Leu Phe Gln Pro 135 140 145 tcg gag gaa aac tcc caa ggc gct aac aag atg gtc gcc ggc ggt tta 595 Ser Glu Glu Asn Ser Gln Gly Ala Asn Lys Met Val Ala Gly Gly Leu 150 155 160 165 gtt gat ctg atc cca cgc cct gat gtg tgc ttt ggc cag cat gta gtc 643 Val Asp Leu Ile Pro Arg Pro Asp Val Cys Phe Gly Gln His Val Val 170 175 180 ccc ggt gct gca gga acc gtg atg agc atg cct ggc ggt gct ctc gct 691 Pro Gly Ala Ala Gly Thr Val Met Ser Met Pro Gly Gly Ala Leu Ala 185 190 195 gcc tgc gat tcc att gaa atc cgc att cag ggt cgc agc gcc cat ggt 739 Ala Cys Asp Ser Ile Glu Ile Arg Ile Gln Gly Arg Ser Ala His Gly 200 205 210 tcc atg cct cat aat tcc atc gat ccc act tat gtt gca gcg atg att 787 Ser Met Pro His Asn Ser Ile Asp Pro Thr Tyr Val Ala Ala Met Ile 215 220 225 gtc gtg cga ctc caa gga atc gtg ggc cgc gag gtt tct cca gag gat 835 Val Val Arg Leu Gln Gly Ile Val Gly Arg Glu Val Ser Pro Glu Asp 230 235 240 245 ttc gcc gtt att tct gtg ggc acc ctc cag tcg ggc aac acc aac aac 883 Phe Ala Val Ile Ser Val Gly Thr Leu Gln Ser Gly Asn Thr Asn Asn 250 255 260 acc att cca gca agt gct cgt ttg gtg ttg aac tgc cgt ttc tac aac 931 Thr Ile Pro Ala Ser Ala Arg Leu Val Leu Asn Cys Arg Phe Tyr Asn 265 270 275 gac aaa gtc aag cac aag gtc tac cga gcc atc gaa cgt gtt gtc cgt 979 Asp Lys Val Lys His Lys Val Tyr Arg Ala Ile Glu Arg Val Val Arg 280 285 290 ggt gaa tgc ctt gct tcc ggt att gag gaa gaa cct gtc att gag tac 1027 Gly Glu Cys Leu Ala Ser Gly Ile Glu Glu Glu Pro Val Ile Glu Tyr 295 300 305 ttc gcc cac ggt gat ctc acc aac aac acc cct gtt gtc ttc gat act 1075 Phe Ala His Gly Asp Leu Thr Asn Asn Thr Pro Val Val Phe Asp Thr 310 315 320 325 gtg cgc cct gtc ttc gac gat gtt ttc ggc gag gat tct att gac gct 1123 Val Arg Pro Val Phe Asp Asp Val Phe Gly Glu Asp Ser Ile Asp Ala 330 335 340 tac cgg tgg act gcg tcg gag gat ttc ccc tcc att cct aag gca ttc 1171 Tyr Arg Trp Thr Ala Ser Glu Asp Phe Pro Ser Ile Pro Lys Ala Phe 345 350 355 aac agc cct tac ctg tac tgg acg att ggt gtc acg ccg cgc gat cag 1219 Asn Ser Pro Tyr Leu Tyr Trp Thr Ile Gly Val Thr Pro Arg Asp Gln 360 365 370 tgg aca gaa gcc gta gaa aga gac cgc gtg gca tcg gat gtg cca gcc 1267 Trp Thr Glu Ala Val Glu Arg Asp Arg Val Ala Ser Asp Val Pro Ala 375 380 385 aat cac atg gga gat ttc ctc cct gat tat gcg ccg acg atg tcc gct 1315 Asn His Met Gly Asp Phe Leu Pro Asp Tyr Ala Pro Thr Met Ser Ala 390 395 400 405 gcc acc cgc gca gcc gca gcc gcg ctg ctg acc tac ttg gga act aac 1363 Ala Thr Arg Ala Ala Ala Ala Ala Leu Leu Thr Tyr Leu Gly Thr Asn 410 415 420 taatcatcta gttttctgcg acg 1386 <210> 366 <211> 421 <212> PRT <213> Corynebacterium glutamicum <400> 366 Met Ser Arg Ile Ser Glu Leu Leu Asn Asn His Gly Val Asp Leu Ser 1 5 10 15 Trp Gln Glu Ala Ala Tyr Gln Asp Phe His Glu His Pro Glu Leu Ser 20 25 30 Gly Phe Glu Ser Glu Thr Ala Asp Arg Ile Gln Lys Tyr Leu Glu Arg 35 40 45 Phe Asp Cys Glu Val Ile Pro Asn Val Gly Gly Tyr Gly Ile Leu Ala 50 55 60 Val Phe Arg Asn Gly Ser Thr Asp Pro Gly Ala Pro Val Ala Leu Met 65 70 75 80 Arg Ala Asp Phe Asp Gly Leu Pro Val Lys Glu Ile Thr Gly Val Pro 85 90 95 Phe Ala Ser Thr Arg Met Arg Pro His Asp Gly Ala Asn Val His Val 100 105 110 Met His Ala Cys Gly His Asp Val His Val Thr Ala Leu Leu Gly Ala 115 120 125 Cys Ala Ile Leu Asp Glu Arg Arg Asp Ala Trp Glu Gly Thr Phe Ile 130 135 140 Ala Leu Phe Gln Pro Ser Glu Glu Asn Ser Gln Gly Ala Asn Lys Met 145 150 155 160 Val Ala Gly Gly Leu Val Asp Leu Ile Pro Arg Pro Asp Val Cys Phe 165 170 175 Gly Gln His Val Val Pro Gly Ala Ala Gly Thr Val Met Ser Met Pro 180 185 190 Gly Gly Ala Leu Ala Ala Cys Asp Ser Ile Glu Ile Arg Ile Gln Gly 195 200 205 Arg Ser Ala His Gly Ser Met Pro His Asn Ser Ile Asp Pro Thr Tyr 210 215 220 Val Ala Ala Met Ile Val Val Arg Leu Gln Gly Ile Val Gly Arg Glu 225 230 235 240 Val Ser Pro Glu Asp Phe Ala Val Ile Ser Val Gly Thr Leu Gln Ser 245 250 255 Gly Asn Thr Asn Asn Thr Ile Pro Ala Ser Ala Arg Leu Val Leu Asn 260 265 270 Cys Arg Phe Tyr Asn Asp Lys Val Lys His Lys Val Tyr Arg Ala Ile 275 280 285 Glu Arg Val Val Arg Gly Glu Cys Leu Ala Ser Gly Ile Glu Glu Glu 290 295 300 Pro Val Ile Glu Tyr Phe Ala His Gly Asp Leu Thr Asn Asn Thr Pro 305 310 315 320 Val Val Phe Asp Thr Val Arg Pro Val Phe Asp Asp Val Phe Gly Glu 325 330 335 Asp Ser Ile Asp Ala Tyr Arg Trp Thr Ala Ser Glu Asp Phe Pro Ser 340 345 350 Ile Pro Lys Ala Phe Asn Ser Pro Tyr Leu Tyr Trp Thr Ile Gly Val 355 360 365 Thr Pro Arg Asp Gln Trp Thr Glu Ala Val Glu Arg Asp Arg Val Ala 370 375 380 Ser Asp Val Pro Ala Asn His Met Gly Asp Phe Leu Pro Asp Tyr Ala 385 390 395 400 Pro Thr Met Ser Ala Ala Thr Arg Ala Ala Ala Ala Ala Leu Leu Thr 405 410 415 Tyr Leu Gly Thr Asn 420 <210> 367 <211> 3462 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3439) <223> RXS02234 <400> 367 acccagaggc cgctgccggc ccaaatgatg caagccccct gtttgaccag tttgttgagc 60 tgatggatgc agacgctcag aagaaaggcg cataaataac atg cca aag cgt tca 115 Met Pro Lys Arg Ser 1 5 gat att aac cac gtc ctc gtc atc ggt tcc ggc ccc atc gtc att ggc 163 Asp Ile Asn His Val Leu Val Ile Gly Ser Gly Pro Ile Val Ile Gly 10 15 20 cag gca tgt gaa ttc gac tac tcc ggc acc cag gct tgc cgc gtg ctg 211 Gln Ala Cys Glu Phe Asp Tyr Ser Gly Thr Gln Ala Cys Arg Val Leu 25 30 35 aag gaa gag gga ctg cgc gtc acc ctc atc aac tcc aac cca gca acg 259 Lys Glu Glu Gly Leu Arg Val Thr Leu Ile Asn Ser Asn Pro Ala Thr 40 45 50 atc atg acc gac cca gaa atg gct gac cac acc tac gtg gag cca atc 307 Ile Met Thr Asp Pro Glu Met Ala Asp His Thr Tyr Val Glu Pro Ile 55 60 65 gag ccg gaa tac atc gac aag att ttc gct aag gaa atc gag cag ggc 355 Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala Lys Glu Ile Glu Gln Gly 70 75 80 85 cac cca atc gac gcc gtc ctg gca acc ctt ggt ggc cag act gca ctt 403 His Pro Ile Asp Ala Val Leu Ala Thr Leu Gly Gly Gln Thr Ala Leu 90 95 100 aac gca gct atc cag ctg gat cgc ctc ggc atc ctg gaa aag tac ggc 451 Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly Ile Leu Glu Lys Tyr Gly 105 110 115 gtt gaa ctc atc ggt gca gac atc gat gcc att gag cgc ggc gaa gat 499 Val Glu Leu Ile Gly Ala Asp Ile Asp Ala Ile Glu Arg Gly Glu Asp 120 125 130 cgc cag aag ttc aag gat att gtc acc acc atc ggt ggc gaa tcc gcg 547 Arg Gln Lys Phe Lys Asp Ile Val Thr Thr Ile Gly Gly Glu Ser Ala 135 140 145 cgt tcc cgc gtc tgc cac aac atg gaa gaa gtc cac gag act gtc gca 595 Arg Ser Arg Val Cys His Asn Met Glu Glu Val His Glu Thr Val Ala 150 155 160 165 gaa ctc ggc ctt cca gta gtc gtg cgt cca tcc ttc act atg ggt ggc 643 Glu Leu Gly Leu Pro Val Val Val Arg Pro Ser Phe Thr Met Gly Gly 170 175 180 ctg ggc tcc ggt ctt gca tac aac acc gaa gac ctt gag cgc atc gct 691 Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu Asp Leu Glu Arg Ile Ala 185 190 195 ggt ggc gga ctt gct gca tct cct gaa gca aac gtc ttg atc gaa gaa 739 Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala Asn Val Leu Ile Glu Glu 200 205 210 tcc atc ctt ggt tgg aag gaa ttc gag ctc gag ctc atg cgc gat acc 787 Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu Glu Leu Met Arg Asp Thr 215 220 225 gca gac aac gtt gtg gtt atc tgc tcc att gaa aac gtc gac gca ctg 835 Ala Asp Asn Val Val Val Ile Cys Ser Ile Glu Asn Val Asp Ala Leu 230 235 240 245 ggc gtg cac acc ggc gac tct gtc acc gtg gca cct gcc ctg acc ctg 883 Gly Val His Thr Gly Asp Ser Val Thr Val Ala Pro Ala Leu Thr Leu 250 255 260 act gac cgt gaa ttc cag aag atg cgc gat cag ggt atc gcc atc atc 931 Thr Asp Arg Glu Phe Gln Lys Met Arg Asp Gln Gly Ile Ala Ile Ile 265 270 275 cgc gag gtc ggc gtg gac acc ggt gga tgt aac atc cag ttc gcc atc 979 Arg Glu Val Gly Val Asp Thr Gly Gly Cys Asn Ile Gln Phe Ala Ile 280 285 290 aac cca gtt gat ggc cgc atc atc acc att gag atg aac cca cgt gtg 1027 Asn Pro Val Asp Gly Arg Ile Ile Thr Ile Glu Met Asn Pro Arg Val 295 300 305 tct cgt tcc tcc gct ctg gca tcc aag gca acg ggc ttc cca att gcc 1075 Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala Thr Gly Phe Pro Ile Ala 310 315 320 325 aag atg gct gcc aag ctg gct atc gga tac acc ctg gat gag atc acc 1123 Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr Thr Leu Asp Glu Ile Thr 330 335 340 aac gac atc act ggt gaa acc cca gct gcg ttt gag ccc acc atc gac 1171 Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala Phe Glu Pro Thr Ile Asp 345 350 355 tac gtc gtg gtc aag gcc cca cgc ttt gct ttc gag aag ttt gtc ggc 1219 Tyr Val Val Val Lys Ala Pro Arg Phe Ala Phe Glu Lys Phe Val Gly 360 365 370 gct gat gac act ttg acc acc acc atg aag tcc gtc ggt gag gtc atg 1267 Ala Asp Asp Thr Leu Thr Thr Thr Met Lys Ser Val Gly Glu Val Met 375 380 385 tcc ctg ggc cgc aac tac att gca gca ctg aac aag gca ctg cgt tcc 1315 Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu Asn Lys Ala Leu Arg Ser 390 395 400 405 ctg gaa acc aag cag cag ggt ttc tgg acc aag cct gat gag ttc ttc 1363 Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr Lys Pro Asp Glu Phe Phe 410 415 420 gca ggg gag cgc gct acc gat aag gca gct gtt ctg gaa gat ctc aag 1411 Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala Val Leu Glu Asp Leu Lys 425 430 435 cgc cca acc gaa ggc cgc ctc tac gac gtt gag ctg gca atg cgc ctt 1459 Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val Glu Leu Ala Met Arg Leu 440 445 450 ggc gca agc gtg gaa gaa ctc tac gaa gca tct tct att gat cct tgg 1507 Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala Ser Ser Ile Asp Pro Trp 455 460 465 ttc ctc gcc gag ctt gaa gct ctc gtg cag ttc cgc cag aag ctc gtt 1555 Phe Leu Ala Glu Leu Glu Ala Leu Val Gln Phe Arg Gln Lys Leu Val 470 475 480 485 gac gca cca ttc cta aac gaa gat ctc ctg cgc gaa gca aag ttc atg 1603 Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu Arg Glu Ala Lys Phe Met 490 495 500 ggt ctg tcc gac ctg cag atc gca gcc ctt cgc cca gag ttc gct ggc 1651 Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu Arg Pro Glu Phe Ala Gly 505 510 515 gaa gac ggc gta cgc acc ttg cgt ctg tcc cta ggc atc cgc cca gta 1699 Glu Asp Gly Val Arg Thr Leu Arg Leu Ser Leu Gly Ile Arg Pro Val 520 525 530 ttc aag act gtg gat acc tgt gca gca gag ttt gaa gct aag act ccg 1747 Phe Lys Thr Val Asp Thr Cys Ala Ala Glu Phe Glu Ala Lys Thr Pro 535 540 545 tac cac tac tcc gca tac gag ctg gat cca gca gct gag tct gag gtc 1795 Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro Ala Ala Glu Ser Glu Val 550 555 560 565 gca cca cag act gag cgt gaa aag gtc ctg atc ttg ggc tcc ggt cca 1843 Ala Pro Gln Thr Glu Arg Glu Lys Val Leu Ile Leu Gly Ser Gly Pro 570 575 580 aac cgc atc ggc cag ggc atc gag ttc gac tac tcc tgt gtt cac gca 1891 Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp Tyr Ser Cys Val His Ala 585 590 595 gct ctt gag ctc tcc cgc gtc ggc tac gaa act gtc atg gtc aac tgc 1939 Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu Thr Val Met Val Asn Cys 600 605 610 aac cca gag acc gtg tcc acc gac tac gac acc gct gac cgc ctg tac 1987 Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp Thr Ala Asp Arg Leu Tyr 615 620 625 ttc gag cca ctg acc ttc gaa gac gtc atg gag gtc tac cac gct gag 2035 Phe Glu Pro Leu Thr Phe Glu Asp Val Met Glu Val Tyr His Ala Glu 630 635 640 645 gcg cag tcc ggc acc gtc gca ggt gtt atc gtc cag ctt ggt ggc cag 2083 Ala Gln Ser Gly Thr Val Ala Gly Val Ile Val Gln Leu Gly Gly Gln 650 655 660 act cct ctg ggc ttg gca gat cgt ttg aag aag gct ggc gtc cct gtc 2131 Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys Lys Ala Gly Val Pro Val 665 670 675 att ggt acc tcc cca gag gca atc gac atg gct gag gac cgt ggc gag 2179 Ile Gly Thr Ser Pro Glu Ala Ile Asp Met Ala Glu Asp Arg Gly Glu 680 685 690 ttc ggt gca ctg ctg aac cgc gag cag ctt cct gct cca gca ttc ggc 2227 Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu Pro Ala Pro Ala Phe Gly 695 700 705 acc gca acc tct ttc gaa gag gct cgc aca gta gcc gat gag atc agc 2275 Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr Val Ala Asp Glu Ile Ser 710 715 720 725 tac cca gtg ctg gtt cgc cct tcc tac gtc ttg ggt ggc cgt ggc atg 2323 Tyr Pro Val Leu Val Arg Pro Ser Tyr Val Leu Gly Gly Arg Gly Met 730 735 740 gag att gtc tac gat gag gct tcc ctc gag gat tac atc aac cgc gca 2371 Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu Asp Tyr Ile Asn Arg Ala 745 750 755 act gag ttg tct tct gac cac cca gtg ctg gtt gac cgc ttc cta gac 2419 Thr Glu Leu Ser Ser Asp His Pro Val Leu Val Asp Arg Phe Leu Asp 760 765 770 aac gct att gag atc gac gtc gac gca ctg tgc gac ggc gac gag gtc 2467 Asn Ala Ile Glu Ile Asp Val Asp Ala Leu Cys Asp Gly Asp Glu Val 775 780 785 tac ctg gca ggc gtc atg gag cac atc gag gaa gcc ggc att cac tcc 2515 Tyr Leu Ala Gly Val Met Glu His Ile Glu Glu Ala Gly Ile His Ser 790 795 800 805 ggt gac tcc gca tgt gca ctt cct cca atg act ttg ggc gca cag gac 2563 Gly Asp Ser Ala Cys Ala Leu Pro Pro Met Thr Leu Gly Ala Gln Asp 810 815 820 atc gag aag gtc cgc gaa gca acc aag aag ctg gct ctg ggc atc ggt 2611 Ile Glu Lys Val Arg Glu Ala Thr Lys Lys Leu Ala Leu Gly Ile Gly 825 830 835 gta cag ggc ctg atg aac gtc cag tac gca ctc aag gac gac atc ctc 2659 Val Gln Gly Leu Met Asn Val Gln Tyr Ala Leu Lys Asp Asp Ile Leu 840 845 850 tac gtc atc gag gca aac cca cgt gca tcc cgc acc gtg ccg ttc gtc 2707 Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser Arg Thr Val Pro Phe Val 855 860 865 tcc aag gca acg ggc gtc aac ctg gcc aag gca gca tcc cgt atc gca 2755 Ser Lys Ala Thr Gly Val Asn Leu Ala Lys Ala Ala Ser Arg Ile Ala 870 875 880 885 gtg ggc gcc acc atc aag gat ctc caa gat gag ggc atg att cct acc 2803 Val Gly Ala Thr Ile Lys Asp Leu Gln Asp Glu Gly Met Ile Pro Thr 890 895 900 gag tac gac ggc ggc tcc ttg cca ctg gac gct cca atc gct gtg aag 2851 Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp Ala Pro Ile Ala Val Lys 905 910 915 gaa gca gtg ttg ccg ttc aac cgc ttc cgt cgc cca gat gga aag acc 2899 Glu Ala Val Leu Pro Phe Asn Arg Phe Arg Arg Pro Asp Gly Lys Thr 920 925 930 ctg gac acc ctg ctt tcc cca gag atg aag tcc act ggc gag gtc atg 2947 Leu Asp Thr Leu Leu Ser Pro Glu Met Lys Ser Thr Gly Glu Val Met 935 940 945 ggc ttg gcc aac aac ttc ggc gct gca tat gca aag gct gaa gct ggc 2995 Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr Ala Lys Ala Glu Ala Gly 950 955 960 965 gcg ttt ggt gca ttg cca acc gaa ggc acc gtc ttc gtg acc gtg gct 3043 Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr Val Phe Val Thr Val Ala 970 975 980 aac cgc gac aag cgc acc ctg atc ctg cca atc cag cgc ctg gcg ttg 3091 Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro Ile Gln Arg Leu Ala Leu 985 990 995 atg ggc tac aag atc ctc gcc acc gaa ggc acc gca ggc atg ctg cgc 3139 Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly Thr Ala Gly Met Leu Arg 1000 1005 1010 cgc aac ggc att gag tgt gaa gtt gtg ctc aag gct tcc gac atc cgc 3187 Arg Asn Gly Ile Glu Cys Glu Val Val Leu Lys Ala Ser Asp Ile Arg 1015 1020 1025 gaa ggt gta gag ggc aag tcc atc gtg gat cgt atc cgc gaa ggc gaa 3235 Glu Gly Val Glu Gly Lys Ser Ile Val Asp Arg Ile Arg Glu Gly Glu 1030 1035 1040 1045 gtt gac ctc atc ctc aac acc cca gct ggt tct gct ggc gct cgc cac 3283 Val Asp Leu Ile Leu Asn Thr Pro Ala Gly Ser Ala Gly Ala Arg His 1050 1055 1060 gat ggc tac gat atc cgc gca gca gca gtg acc gtg ggt gtt ccg ctg 3331 Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val Thr Val Gly Val Pro Leu 1065 1070 1075 atc acc act gtt cag ggt gtc acc gca gct gtc cag ggc ata gag gcc 3379 Ile Thr Thr Val Gln Gly Val Thr Ala Ala Val Gln Gly Ile Glu Ala 1080 1085 1090 ctg cgt gag ggc gtt gtc agc gtc cgc gcg ctg cag gaa ctc gac cac 3427 Leu Arg Glu Gly Val Val Ser Val Arg Ala Leu Gln Glu Leu Asp His 1095 1100 1105 gca gtc aag gct taagccctat gacattcggc gag 3462 Ala Val Lys Ala 1110 <210> 368 <211> 1113 <212> PRT <213> Corynebacterium glutamicum <400> 368 Met Pro Lys Arg Ser Asp Ile Asn His Val Leu Val Ile Gly Ser Gly 1 5 10 15 Pro Ile Val Ile Gly Gln Ala Cys Glu Phe Asp Tyr Ser Gly Thr Gln 20 25 30 Ala Cys Arg Val Leu Lys Glu Glu Gly Leu Arg Val Thr Leu Ile Asn 35 40 45 Ser Asn Pro Ala Thr Ile Met Thr Asp Pro Glu Met Ala Asp His Thr 50 55 60 Tyr Val Glu Pro Ile Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala Lys 65 70 75 80 Glu Ile Glu Gln Gly His Pro Ile Asp Ala Val Leu Ala Thr Leu Gly 85 90 95 Gly Gln Thr Ala Leu Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly Ile 100 105 110 Leu Glu Lys Tyr Gly Val Glu Leu Ile Gly Ala Asp Ile Asp Ala Ile 115 120 125 Glu Arg Gly Glu Asp Arg Gln Lys Phe Lys Asp Ile Val Thr Thr Ile 130 135 140 Gly Gly Glu Ser Ala Arg Ser Arg Val Cys His Asn Met Glu Glu Val 145 150 155 160 His Glu Thr Val Ala Glu Leu Gly Leu Pro Val Val Val Arg Pro Ser 165 170 175 Phe Thr Met Gly Gly Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu Asp 180 185 190 Leu Glu Arg Ile Ala Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala Asn 195 200 205 Val Leu Ile Glu Glu Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu Glu 210 215 220 Leu Met Arg Asp Thr Ala Asp Asn Val Val Val Ile Cys Ser Ile Glu 225 230 235 240 Asn Val Asp Ala Leu Gly Val His Thr Gly Asp Ser Val Thr Val Ala 245 250 255 Pro Ala Leu Thr Leu Thr Asp Arg Glu Phe Gln Lys Met Arg Asp Gln 260 265 270 Gly Ile Ala Ile Ile Arg Glu Val Gly Val Asp Thr Gly Gly Cys Asn 275 280 285 Ile Gln Phe Ala Ile Asn Pro Val Asp Gly Arg Ile Ile Thr Ile Glu 290 295 300 Met Asn Pro Arg Val Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala Thr 305 310 315 320 Gly Phe Pro Ile Ala Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr Thr 325 330 335 Leu Asp Glu Ile Thr Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala Phe 340 345 350 Glu Pro Thr Ile Asp Tyr Val Val Val Lys Ala Pro Arg Phe Ala Phe 355 360 365 Glu Lys Phe Val Gly Ala Asp Asp Thr Leu Thr Thr Thr Met Lys Ser 370 375 380 Val Gly Glu Val Met Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu Asn 385 390 395 400 Lys Ala Leu Arg Ser Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr Lys 405 410 415 Pro Asp Glu Phe Phe Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala Val 420 425 430 Leu Glu Asp Leu Lys Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val Glu 435 440 445 Leu Ala Met Arg Leu Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala Ser 450 455 460 Ser Ile Asp Pro Trp Phe Leu Ala Glu Leu Glu Ala Leu Val Gln Phe 465 470 475 480 Arg Gln Lys Leu Val Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu Arg 485 490 495 Glu Ala Lys Phe Met Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu Arg 500 505 510 Pro Glu Phe Ala Gly Glu Asp Gly Val Arg Thr Leu Arg Leu Ser Leu 515 520 525 Gly Ile Arg Pro Val Phe Lys Thr Val Asp Thr Cys Ala Ala Glu Phe 530 535 540 Glu Ala Lys Thr Pro Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro Ala 545 550 555 560 Ala Glu Ser Glu Val Ala Pro Gln Thr Glu Arg Glu Lys Val Leu Ile 565 570 575 Leu Gly Ser Gly Pro Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp Tyr 580 585 590 Ser Cys Val His Ala Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu Thr 595 600 605 Val Met Val Asn Cys Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp Thr 610 615 620 Ala Asp Arg Leu Tyr Phe Glu Pro Leu Thr Phe Glu Asp Val Met Glu 625 630 635 640 Val Tyr His Ala Glu Ala Gln Ser Gly Thr Val Ala Gly Val Ile Val 645 650 655 Gln Leu Gly Gly Gln Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys Lys 660 665 670 Ala Gly Val Pro Val Ile Gly Thr Ser Pro Glu Ala Ile Asp Met Ala 675 680 685 Glu Asp Arg Gly Glu Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu Pro 690 695 700 Ala Pro Ala Phe Gly Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr Val 705 710 715 720 Ala Asp Glu Ile Ser Tyr Pro Val Leu Val Arg Pro Ser Tyr Val Leu 725 730 735 Gly Gly Arg Gly Met Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu Asp 740 745 750 Tyr Ile Asn Arg Ala Thr Glu Leu Ser Ser Asp His Pro Val Leu Val 755 760 765 Asp Arg Phe Leu Asp Asn Ala Ile Glu Ile Asp Val Asp Ala Leu Cys 770 775 780 Asp Gly Asp Glu Val Tyr Leu Ala Gly Val Met Glu His Ile Glu Glu 785 790 795 800 Ala Gly Ile His Ser Gly Asp Ser Ala Cys Ala Leu Pro Pro Met Thr 805 810 815 Leu Gly Ala Gln Asp Ile Glu Lys Val Arg Glu Ala Thr Lys Lys Leu 820 825 830 Ala Leu Gly Ile Gly Val Gln Gly Leu Met Asn Val Gln Tyr Ala Leu 835 840 845 Lys Asp Asp Ile Leu Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser Arg 850 855 860 Thr Val Pro Phe Val Ser Lys Ala Thr Gly Val Asn Leu Ala Lys Ala 865 870 875 880 Ala Ser Arg Ile Ala Val Gly Ala Thr Ile Lys Asp Leu Gln Asp Glu 885 890 895 Gly Met Ile Pro Thr Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp Ala 900 905 910 Pro Ile Ala Val Lys Glu Ala Val Leu Pro Phe Asn Arg Phe Arg Arg 915 920 925 Pro Asp Gly Lys Thr Leu Asp Thr Leu Leu Ser Pro Glu Met Lys Ser 930 935 940 Thr Gly Glu Val Met Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr Ala 945 950 955 960 Lys Ala Glu Ala Gly Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr Val 965 970 975 Phe Val Thr Val Ala Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro Ile 980 985 990 Gln Arg Leu Ala Leu Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly Thr 995 1000 1005 Ala Gly Met Leu Arg Arg Asn Gly Ile Glu Cys Glu Val Val Leu Lys 1010 1015 1020 Ala Ser Asp Ile Arg Glu Gly Val Glu Gly Lys Ser Ile Val Asp Arg 1025 1030 1035 1040 Ile Arg Glu Gly Glu Val Asp Leu Ile Leu Asn Thr Pro Ala Gly Ser 1045 1050 1055 Ala Gly Ala Arg His Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val Thr 1060 1065 1070 Val Gly Val Pro Leu Ile Thr Thr Val Gln Gly Val Thr Ala Ala Val 1075 1080 1085 Gln Gly Ile Glu Ala Leu Arg Glu Gly Val Val Ser Val Arg Ala Leu 1090 1095 1100 Gln Glu Leu Asp His Ala Val Lys Ala 1105 1110 <210> 369 <211> 3221 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(3198) <223> FRXA02234 <400> 369 ggc tcc aac cca gca acg atc atg acc gac cca gaa atg gct gac cac 48 Gly Ser Asn Pro Ala Thr Ile Met Thr Asp Pro Glu Met Ala Asp His 1 5 10 15 acc tac gtg gag cca atc gag ccg gaa tac atc gac aag att ttc gct 96 Thr Tyr Val Glu Pro Ile Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala 20 25 30 aag gaa atc gag cag ggc cac cca atc gac gcc gtc ctg gca acc ctt 144 Lys Glu Ile Glu Gln Gly His Pro Ile Asp Ala Val Leu Ala Thr Leu 35 40 45 ggt ggc cag act gca ctt aac gca gct atc cag ctg gat cgc ctc ggc 192 Gly Gly Gln Thr Ala Leu Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly 50 55 60 atc ctg gaa aag tac ggc gtt gaa ctc atc ggt gca gac atc gat gcc 240 Ile Leu Glu Lys Tyr Gly Val Glu Leu Ile Gly Ala Asp Ile Asp Ala 65 70 75 80 att gag cgc ggc gaa gat cgc cag aag ttc aag gat att gtc acc acc 288 Ile Glu Arg Gly Glu Asp Arg Gln Lys Phe Lys Asp Ile Val Thr Thr 85 90 95 atc ggt ggc gaa tcc gcg cgt tcc cgc gtc tgc cac aac atg gaa gaa 336 Ile Gly Gly Glu Ser Ala Arg Ser Arg Val Cys His Asn Met Glu Glu 100 105 110 gtc cac gag act gtc gca gaa ctc ggc ctt cca gta gtc gtg cgt cca 384 Val His Glu Thr Val Ala Glu Leu Gly Leu Pro Val Val Val Arg Pro 115 120 125 tcc ttc act atg ggt ggc ctg ggc tcc ggt ctt gca tac aac acc gaa 432 Ser Phe Thr Met Gly Gly Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu 130 135 140 gac ctt gag cgc atc gct ggt ggc gga ctt gct gca tct cct gaa gca 480 Asp Leu Glu Arg Ile Ala Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala 145 150 155 160 aac gtc ttg atc gaa gaa tcc atc ctt ggt tgg aag gaa ttc gag ctc 528 Asn Val Leu Ile Glu Glu Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu 165 170 175 gag ctc atg cgc gat acc gca gac aac gtt gtg gtt atc tgc tcc att 576 Glu Leu Met Arg Asp Thr Ala Asp Asn Val Val Val Ile Cys Ser Ile 180 185 190 gaa aac gtc gac gca ctg ggc gtg cac acc ggc gac tct gtc acc gtg 624 Glu Asn Val Asp Ala Leu Gly Val His Thr Gly Asp Ser Val Thr Val 195 200 205 gca cct gcc ctg acc ctg act gac cgt gaa ttc cag aag atg cgc gat 672 Ala Pro Ala Leu Thr Leu Thr Asp Arg Glu Phe Gln Lys Met Arg Asp 210 215 220 cag ggt atc gcc atc atc cgc gag gtc ggc gtg gac acc ggt gga tgt 720 Gln Gly Ile Ala Ile Ile Arg Glu Val Gly Val Asp Thr Gly Gly Cys 225 230 235 240 aac atc cag ttc gcc atc aac cca gtt gat ggc cgc atc atc acc att 768 Asn Ile Gln Phe Ala Ile Asn Pro Val Asp Gly Arg Ile Ile Thr Ile 245 250 255 gag atg aac cca cgt gtg tct cgt tcc tcc gct ctg gca tcc aag gca 816 Glu Met Asn Pro Arg Val Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala 260 265 270 acg ggc ttc cca att gcc aag atg gct gcc aag ctg gct atc gga tac 864 Thr Gly Phe Pro Ile Ala Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr 275 280 285 acc ctg gat gag atc acc aac gac atc act ggt gaa acc cca gct gcg 912 Thr Leu Asp Glu Ile Thr Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala 290 295 300 ttt gag ccc acc atc gac tac gtc gtg gtc aag gcc cca cgc ttt gct 960 Phe Glu Pro Thr Ile Asp Tyr Val Val Val Lys Ala Pro Arg Phe Ala 305 310 315 320 ttc gag aag ttt gtc ggc gct gat gac act ttg acc acc acc atg aag 1008 Phe Glu Lys Phe Val Gly Ala Asp Asp Thr Leu Thr Thr Thr Met Lys 325 330 335 tcc gtc ggt gag gtc atg tcc ctg ggc cgc aac tac att gca gca ctg 1056 Ser Val Gly Glu Val Met Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu 340 345 350 aac aag gca ctg cgt tcc ctg gaa acc aag cag cag ggt ttc tgg acc 1104 Asn Lys Ala Leu Arg Ser Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr 355 360 365 aag cct gat gag ttc ttc gca ggg gag cgc gct acc gat aag gca gct 1152 Lys Pro Asp Glu Phe Phe Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala 370 375 380 gtt ctg gaa gat ctc aag cgc cca acc gaa ggc cgc ctc tac gac gtt 1200 Val Leu Glu Asp Leu Lys Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val 385 390 395 400 gag ctg gca atg cgc ctt ggc gca agc gtg gaa gaa ctc tac gaa gca 1248 Glu Leu Ala Met Arg Leu Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala 405 410 415 tct tct att gat cct tgg ttc ctc gcc gag ctt gaa gct ctc gtg cag 1296 Ser Ser Ile Asp Pro Trp Phe Leu Ala Glu Leu Glu Ala Leu Val Gln 420 425 430 ttc cgc cag aag ctc gtt gac gca cca ttc cta aac gaa gat ctc ctg 1344 Phe Arg Gln Lys Leu Val Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu 435 440 445 cgc gaa gca aag ttc atg ggt ctg tcc gac ctg cag atc gca gcc ctt 1392 Arg Glu Ala Lys Phe Met Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu 450 455 460 cgc cca gag ttc gct ggc gaa gac ggc gta cgc acc ttg cgt ctg tcc 1440 Arg Pro Glu Phe Ala Gly Glu Asp Gly Val Arg Thr Leu Arg Leu Ser 465 470 475 480 cta ggc atc cgc cca gta ttc aag act gtg gat acc tgt gca gca gag 1488 Leu Gly Ile Arg Pro Val Phe Lys Thr Val Asp Thr Cys Ala Ala Glu 485 490 495 ttt gaa gct aag act ccg tac cac tac tcc gca tac gag ctg gat cca 1536 Phe Glu Ala Lys Thr Pro Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro 500 505 510 gca gct gag tct gag gtc gca cca cag act gag cgt gaa aag gtc ctg 1584 Ala Ala Glu Ser Glu Val Ala Pro Gln Thr Glu Arg Glu Lys Val Leu 515 520 525 atc ttg ggc tcc ggt cca aac cgc atc ggc cag ggc atc gag ttc gac 1632 Ile Leu Gly Ser Gly Pro Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp 530 535 540 tac tcc tgt gtt cac gca gct ctt gag ctc tcc cgc gtc ggc tac gaa 1680 Tyr Ser Cys Val His Ala Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu 545 550 555 560 act gtc atg gtc aac tgc aac cca gag acc gtg tcc acc gac tac gac 1728 Thr Val Met Val Asn Cys Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp 565 570 575 acc gct gac cgc ctg tac ttc gag cca ctg acc ttc gaa gac gtc atg 1776 Thr Ala Asp Arg Leu Tyr Phe Glu Pro Leu Thr Phe Glu Asp Val Met 580 585 590 gag gtc tac cac gct gag gcg cag tcc ggc acc gtc gca ggt gtt atc 1824 Glu Val Tyr His Ala Glu Ala Gln Ser Gly Thr Val Ala Gly Val Ile 595 600 605 gtc cag ctt ggt ggc cag act cct ctg ggc ttg gca gat cgt ttg aag 1872 Val Gln Leu Gly Gly Gln Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys 610 615 620 aag gct ggc gtc cct gtc att ggt acc tcc cca gag gca atc gac atg 1920 Lys Ala Gly Val Pro Val Ile Gly Thr Ser Pro Glu Ala Ile Asp Met 625 630 635 640 gct gag gac cgt ggc gag ttc ggt gca ctg ctg aac cgc gag cag ctt 1968 Ala Glu Asp Arg Gly Glu Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu 645 650 655 cct gct cca gca ttc ggc acc gca acc tct ttc gaa gag gct cgc aca 2016 Pro Ala Pro Ala Phe Gly Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr 660 665 670 gta gcc gat gag atc agc tac cca gtg ctg gtt cgc cct tcc tac gtc 2064 Val Ala Asp Glu Ile Ser Tyr Pro Val Leu Val Arg Pro Ser Tyr Val 675 680 685 ttg ggt ggc cgt ggc atg gag att gtc tac gat gag gct tcc ctc gag 2112 Leu Gly Gly Arg Gly Met Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu 690 695 700 gat tac atc aac cgc gca act gag ttg tct tct gac cac cca gtg ctg 2160 Asp Tyr Ile Asn Arg Ala Thr Glu Leu Ser Ser Asp His Pro Val Leu 705 710 715 720 gtt gac cgc ttc cta gac aac gct att gag atc gac gtc gac gca ctg 2208 Val Asp Arg Phe Leu Asp Asn Ala Ile Glu Ile Asp Val Asp Ala Leu 725 730 735 tgc gac ggc gac gag gtc tac ctg gca ggc gtc atg gag cac atc gag 2256 Cys Asp Gly Asp Glu Val Tyr Leu Ala Gly Val Met Glu His Ile Glu 740 745 750 gaa gcc ggc att cac tcc ggt gac tcc gca tgt gca ctt cct cca atg 2304 Glu Ala Gly Ile His Ser Gly Asp Ser Ala Cys Ala Leu Pro Pro Met 755 760 765 act ttg ggc gca cag gac atc gag aag gtc cgc gaa gca acc aag aag 2352 Thr Leu Gly Ala Gln Asp Ile Glu Lys Val Arg Glu Ala Thr Lys Lys 770 775 780 ctg gct ctg ggc atc ggt gta cag ggc ctg atg aac gtc cag tac gca 2400 Leu Ala Leu Gly Ile Gly Val Gln Gly Leu Met Asn Val Gln Tyr Ala 785 790 795 800 ctc aag gac gac atc ctc tac gtc atc gag gca aac cca cgt gca tcc 2448 Leu Lys Asp Asp Ile Leu Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser 805 810 815 cgc acc gtg ccg ttc gtc tcc aag gca acg ggc gtc aac ctg gcc aag 2496 Arg Thr Val Pro Phe Val Ser Lys Ala Thr Gly Val Asn Leu Ala Lys 820 825 830 gca gca tcc cgt atc gca gtg ggc gcc acc atc aag gat ctc caa gat 2544 Ala Ala Ser Arg Ile Ala Val Gly Ala Thr Ile Lys Asp Leu Gln Asp 835 840 845 gag ggc atg att cct acc gag tac gac ggc ggc tcc ttg cca ctg gac 2592 Glu Gly Met Ile Pro Thr Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp 850 855 860 gct cca atc gct gtg aag gaa gca gtg ttg ccg ttc aac cgc ttc cgt 2640 Ala Pro Ile Ala Val Lys Glu Ala Val Leu Pro Phe Asn Arg Phe Arg 865 870 875 880 cgc cca gat gga aag acc ctg gac acc ctg ctt tcc cca gag atg aag 2688 Arg Pro Asp Gly Lys Thr Leu Asp Thr Leu Leu Ser Pro Glu Met Lys 885 890 895 tcc act ggc gag gtc atg ggc ttg gcc aac aac ttc ggc gct gca tat 2736 Ser Thr Gly Glu Val Met Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr 900 905 910 gca aag gct gaa gct ggc gcg ttt ggt gca ttg cca acc gaa ggc acc 2784 Ala Lys Ala Glu Ala Gly Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr 915 920 925 gtc ttc gtg acc gtg gct aac cgc gac aag cgc acc ctg atc ctg cca 2832 Val Phe Val Thr Val Ala Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro 930 935 940 atc cag cgc ctg gcg ttg atg ggc tac aag atc ctc gcc acc gaa ggc 2880 Ile Gln Arg Leu Ala Leu Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly 945 950 955 960 acc gca ggc atg ctg cgc cgc aac ggc att gag tgt gaa gtt gtg ctc 2928 Thr Ala Gly Met Leu Arg Arg Asn Gly Ile Glu Cys Glu Val Val Leu 965 970 975 aag gct tcc gac atc cgc gaa ggt gta gag ggc aag tcc atc gtg gat 2976 Lys Ala Ser Asp Ile Arg Glu Gly Val Glu Gly Lys Ser Ile Val Asp 980 985 990 cgt atc cgc gaa ggc gaa gtt gac ctc atc ctc aac acc cca gct ggt 3024 Arg Ile Arg Glu Gly Glu Val Asp Leu Ile Leu Asn Thr Pro Ala Gly 995 1000 1005 tct gct ggc gct cgc cac gat ggc tac gat atc cgc gca gca gca gtg 3072 Ser Ala Gly Ala Arg His Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val 1010 1015 1020 acc gtg ggt gtt ccg ctg atc acc act gtt cag ggt gtc acc gca gct 3120 Thr Val Gly Val Pro Leu Ile Thr Thr Val Gln Gly Val Thr Ala Ala 1025 1030 1035 1040 gtc cag ggc ata gag gcc ctg cgt gag ggc gtt gtc agc gtc cgc gcg 3168 Val Gln Gly Ile Glu Ala Leu Arg Glu Gly Val Val Ser Val Arg Ala 1045 1050 1055 ctg cag gaa ctc gac cac gca gtc aag gct taagccctat gacattcggc 3218 Leu Gln Glu Leu Asp His Ala Val Lys Ala 1060 1065 gag 3221 <210> 370 <211> 1066 <212> PRT <213> Corynebacterium glutamicum <400> 370 Gly Ser Asn Pro Ala Thr Ile Met Thr Asp Pro Glu Met Ala Asp His 1 5 10 15 Thr Tyr Val Glu Pro Ile Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala 20 25 30 Lys Glu Ile Glu Gln Gly His Pro Ile Asp Ala Val Leu Ala Thr Leu 35 40 45 Gly Gly Gln Thr Ala Leu Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly 50 55 60 Ile Leu Glu Lys Tyr Gly Val Glu Leu Ile Gly Ala Asp Ile Asp Ala 65 70 75 80 Ile Glu Arg Gly Glu Asp Arg Gln Lys Phe Lys Asp Ile Val Thr Thr 85 90 95 Ile Gly Gly Glu Ser Ala Arg Ser Arg Val Cys His Asn Met Glu Glu 100 105 110 Val His Glu Thr Val Ala Glu Leu Gly Leu Pro Val Val Val Arg Pro 115 120 125 Ser Phe Thr Met Gly Gly Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu 130 135 140 Asp Leu Glu Arg Ile Ala Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala 145 150 155 160 Asn Val Leu Ile Glu Glu Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu 165 170 175 Glu Leu Met Arg Asp Thr Ala Asp Asn Val Val Val Ile Cys Ser Ile 180 185 190 Glu Asn Val Asp Ala Leu Gly Val His Thr Gly Asp Ser Val Thr Val 195 200 205 Ala Pro Ala Leu Thr Leu Thr Asp Arg Glu Phe Gln Lys Met Arg Asp 210 215 220 Gln Gly Ile Ala Ile Ile Arg Glu Val Gly Val Asp Thr Gly Gly Cys 225 230 235 240 Asn Ile Gln Phe Ala Ile Asn Pro Val Asp Gly Arg Ile Ile Thr Ile 245 250 255 Glu Met Asn Pro Arg Val Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala 260 265 270 Thr Gly Phe Pro Ile Ala Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr 275 280 285 Thr Leu Asp Glu Ile Thr Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala 290 295 300 Phe Glu Pro Thr Ile Asp Tyr Val Val Val Lys Ala Pro Arg Phe Ala 305 310 315 320 Phe Glu Lys Phe Val Gly Ala Asp Asp Thr Leu Thr Thr Thr Met Lys 325 330 335 Ser Val Gly Glu Val Met Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu 340 345 350 Asn Lys Ala Leu Arg Ser Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr 355 360 365 Lys Pro Asp Glu Phe Phe Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala 370 375 380 Val Leu Glu Asp Leu Lys Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val 385 390 395 400 Glu Leu Ala Met Arg Leu Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala 405 410 415 Ser Ser Ile Asp Pro Trp Phe Leu Ala Glu Leu Glu Ala Leu Val Gln 420 425 430 Phe Arg Gln Lys Leu Val Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu 435 440 445 Arg Glu Ala Lys Phe Met Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu 450 455 460 Arg Pro Glu Phe Ala Gly Glu Asp Gly Val Arg Thr Leu Arg Leu Ser 465 470 475 480 Leu Gly Ile Arg Pro Val Phe Lys Thr Val Asp Thr Cys Ala Ala Glu 485 490 495 Phe Glu Ala Lys Thr Pro Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro 500 505 510 Ala Ala Glu Ser Glu Val Ala Pro Gln Thr Glu Arg Glu Lys Val Leu 515 520 525 Ile Leu Gly Ser Gly Pro Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp 530 535 540 Tyr Ser Cys Val His Ala Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu 545 550 555 560 Thr Val Met Val Asn Cys Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp 565 570 575 Thr Ala Asp Arg Leu Tyr Phe Glu Pro Leu Thr Phe Glu Asp Val Met 580 585 590 Glu Val Tyr His Ala Glu Ala Gln Ser Gly Thr Val Ala Gly Val Ile 595 600 605 Val Gln Leu Gly Gly Gln Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys 610 615 620 Lys Ala Gly Val Pro Val Ile Gly Thr Ser Pro Glu Ala Ile Asp Met 625 630 635 640 Ala Glu Asp Arg Gly Glu Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu 645 650 655 Pro Ala Pro Ala Phe Gly Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr 660 665 670 Val Ala Asp Glu Ile Ser Tyr Pro Val Leu Val Arg Pro Ser Tyr Val 675 680 685 Leu Gly Gly Arg Gly Met Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu 690 695 700 Asp Tyr Ile Asn Arg Ala Thr Glu Leu Ser Ser Asp His Pro Val Leu 705 710 715 720 Val Asp Arg Phe Leu Asp Asn Ala Ile Glu Ile Asp Val Asp Ala Leu 725 730 735 Cys Asp Gly Asp Glu Val Tyr Leu Ala Gly Val Met Glu His Ile Glu 740 745 750 Glu Ala Gly Ile His Ser Gly Asp Ser Ala Cys Ala Leu Pro Pro Met 755 760 765 Thr Leu Gly Ala Gln Asp Ile Glu Lys Val Arg Glu Ala Thr Lys Lys 770 775 780 Leu Ala Leu Gly Ile Gly Val Gln Gly Leu Met Asn Val Gln Tyr Ala 785 790 795 800 Leu Lys Asp Asp Ile Leu Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser 805 810 815 Arg Thr Val Pro Phe Val Ser Lys Ala Thr Gly Val Asn Leu Ala Lys 820 825 830 Ala Ala Ser Arg Ile Ala Val Gly Ala Thr Ile Lys Asp Leu Gln Asp 835 840 845 Glu Gly Met Ile Pro Thr Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp 850 855 860 Ala Pro Ile Ala Val Lys Glu Ala Val Leu Pro Phe Asn Arg Phe Arg 865 870 875 880 Arg Pro Asp Gly Lys Thr Leu Asp Thr Leu Leu Ser Pro Glu Met Lys 885 890 895 Ser Thr Gly Glu Val Met Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr 900 905 910 Ala Lys Ala Glu Ala Gly Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr 915 920 925 Val Phe Val Thr Val Ala Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro 930 935 940 Ile Gln Arg Leu Ala Leu Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly 945 950 955 960 Thr Ala Gly Met Leu Arg Arg Asn Gly Ile Glu Cys Glu Val Val Leu 965 970 975 Lys Ala Ser Asp Ile Arg Glu Gly Val Glu Gly Lys Ser Ile Val Asp 980 985 990 Arg Ile Arg Glu Gly Glu Val Asp Leu Ile Leu Asn Thr Pro Ala Gly 995 1000 1005 Ser Ala Gly Ala Arg His Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val 1010 1015 1020 Thr Val Gly Val Pro Leu Ile Thr Thr Val Gln Gly Val Thr Ala Ala 1025 1030 1035 1040 Val Gln Gly Ile Glu Ala Leu Arg Glu Gly Val Val Ser Val Arg Ala 1045 1050 1055 Leu Gln Glu Leu Asp His Ala Val Lys Ala 1060 1065 <210> 371 <211> 1389 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1366) <223> RXS02565 <400> 371 ggaaattcga tacagtgcga tgacgcgata ttagaaagaa aaagatgcgc tttacgacga 60 aaccctcacc ctccttcagg aacttatccg caacgcctgc gtg aat gat cta acc 115 Val Asn Asp Leu Thr 1 5 cca gat tca ggt cag gaa att aga aac gcg gaa agc cta gaa cgt ttc 163 Pro Asp Ser Gly Gln Glu Ile Arg Asn Ala Glu Ser Leu Glu Arg Phe 10 15 20 ttt gaa gga acc ccc aac gtt aaa atc acc aag ctg gaa ccg cat ccg 211 Phe Glu Gly Thr Pro Asn Val Lys Ile Thr Lys Leu Glu Pro His Pro 25 30 35 ggc cgg acc tca att atc gtg act gtt cca ggc agc gat cca gat gct 259 Gly Arg Thr Ser Ile Ile Val Thr Val Pro Gly Ser Asp Pro Asp Ala 40 45 50 gag cct tta aca ctg ctt gga cat act gat gtt gtg cct gtt gat ctg 307 Glu Pro Leu Thr Leu Leu Gly His Thr Asp Val Val Pro Val Asp Leu 55 60 65 cct aaa tgg act aaa gat cca ttc ggt gcg gag att tcg gat gga cag 355 Pro Lys Trp Thr Lys Asp Pro Phe Gly Ala Glu Ile Ser Asp Gly Gln 70 75 80 85 att tgg ggt aga ggg tcc gtc gat atg ctc ttt att acc gca acc caa 403 Ile Trp Gly Arg Gly Ser Val Asp Met Leu Phe Ile Thr Ala Thr Gln 90 95 100 gcg gcc gtc acc cgt caa gta gcc cgt gaa ggc ggc ctg cgt ggc acg 451 Ala Ala Val Thr Arg Gln Val Ala Arg Glu Gly Gly Leu Arg Gly Thr 105 110 115 ctg aca ttc gtt ggc gtt gct gat gag gaa gcc cgc ggc gga ctc gga 499 Leu Thr Phe Val Gly Val Ala Asp Glu Glu Ala Arg Gly Gly Leu Gly 120 125 130 gcg aag tgg ctt tcc gaa gaa cac caa aac ctc ttc agc tgg aaa aac 547 Ala Lys Trp Leu Ser Glu Glu His Gln Asn Leu Phe Ser Trp Lys Asn 135 140 145 tgc ctc tcc gaa tcc ggt gga tcg cac ctt cca gtc cac gac ggc agc 595 Cys Leu Ser Glu Ser Gly Gly Ser His Leu Pro Val His Asp Gly Ser 150 155 160 165 gac gca gta gta att aac gtt gga gaa aaa ggt gca gct caa cgt cgt 643 Asp Ala Val Val Ile Asn Val Gly Glu Lys Gly Ala Ala Gln Arg Arg 170 175 180 att cac gtc aat ggc gat gct ggt cat ggt tcc att cct ttc gac cgt 691 Ile His Val Asn Gly Asp Ala Gly His Gly Ser Ile Pro Phe Asp Arg 185 190 195 gac agc gct att gtc aag atc ggt gaa gtc gcc cgc cga atc gct gcc 739 Asp Ser Ala Ile Val Lys Ile Gly Glu Val Ala Arg Arg Ile Ala Ala 200 205 210 gcc gat ctg aag gta gcc aag gac gat atc tgg caa ggc ttc gtc caa 787 Ala Asp Leu Lys Val Ala Lys Asp Asp Ile Trp Gln Gly Phe Val Gln 215 220 225 gcg cac cgt ttc gac cca gaa acg gag cag gcg ctt ctt agc ggg acc 835 Ala His Arg Phe Asp Pro Glu Thr Glu Gln Ala Leu Leu Ser Gly Thr 230 235 240 245 tcc cct gag gcc tac gca gag ttc ggc gga ctc tcc cgc ttc gcc cac 883 Ser Pro Glu Ala Tyr Ala Glu Phe Gly Gly Leu Ser Arg Phe Ala His 250 255 260 gcg gtg tct cat ctc acg atc gcc caa act gtg gtt cgt gca ggt caa 931 Ala Val Ser His Leu Thr Ile Ala Gln Thr Val Val Arg Ala Gly Gln 265 270 275 gcc atc aat gta ttg cca tcg cat gcg tac ttg gaa ctg gat atc cgt 979 Ala Ile Asn Val Leu Pro Ser His Ala Tyr Leu Glu Leu Asp Ile Arg 280 285 290 acc ctt cca ggc caa acc aat gac tat gtt gat gac acc ctg cgt gct 1027 Thr Leu Pro Gly Gln Thr Asn Asp Tyr Val Asp Asp Thr Leu Arg Ala 295 300 305 gct ctg ggc gat ctt gcc gat gaa gta gaa atc gaa cac ctc atc tct 1075 Ala Leu Gly Asp Leu Ala Asp Glu Val Glu Ile Glu His Leu Ile Ser 310 315 320 325 gaa gaa gca acg gtg agc cca act gat tcc agg ttg tat aac acc ttg 1123 Glu Glu Ala Thr Val Ser Pro Thr Asp Ser Arg Leu Tyr Asn Thr Leu 330 335 340 gaa aaa gtt ctt ggt gat ttc ttc ccc gat gcg cct gtg gtc cca att 1171 Glu Lys Val Leu Gly Asp Phe Phe Pro Asp Ala Pro Val Val Pro Ile 345 350 355 att tcc tct ggt ggc tct gac ctg cgc ttt ggt cgt cga cta ggc ggt 1219 Ile Ser Ser Gly Gly Ser Asp Leu Arg Phe Gly Arg Arg Leu Gly Gly 360 365 370 gtt ggt tat ggt ttt gca gtt cat gca cgt gaa cga act ttg gcg gaa 1267 Val Gly Tyr Gly Phe Ala Val His Ala Arg Glu Arg Thr Leu Ala Glu 375 380 385 gca atg ggg caa ctt cac tcc cat gac gag gcg ctg tac ctg gaa gat 1315 Ala Met Gly Gln Leu His Ser His Asp Glu Ala Leu Tyr Leu Glu Asp 390 395 400 405 ctt gaa ctg act gtt cgg ggt tat gac tcc gtc gtg cgt gaa ttc cta 1363 Leu Glu Leu Thr Val Arg Gly Tyr Asp Ser Val Val Arg Glu Phe Leu 410 415 420 ggc taaaaacatg aagcaggagt ctt 1389 Gly <210> 372 <211> 422 <212> PRT <213> Corynebacterium glutamicum <400> 372 Val Asn Asp Leu Thr Pro Asp Ser Gly Gln Glu Ile Arg Asn Ala Glu 1 5 10 15 Ser Leu Glu Arg Phe Phe Glu Gly Thr Pro Asn Val Lys Ile Thr Lys 20 25 30 Leu Glu Pro His Pro Gly Arg Thr Ser Ile Ile Val Thr Val Pro Gly 35 40 45 Ser Asp Pro Asp Ala Glu Pro Leu Thr Leu Leu Gly His Thr Asp Val 50 55 60 Val Pro Val Asp Leu Pro Lys Trp Thr Lys Asp Pro Phe Gly Ala Glu 65 70 75 80 Ile Ser Asp Gly Gln Ile Trp Gly Arg Gly Ser Val Asp Met Leu Phe 85 90 95 Ile Thr Ala Thr Gln Ala Ala Val Thr Arg Gln Val Ala Arg Glu Gly 100 105 110 Gly Leu Arg Gly Thr Leu Thr Phe Val Gly Val Ala Asp Glu Glu Ala 115 120 125 Arg Gly Gly Leu Gly Ala Lys Trp Leu Ser Glu Glu His Gln Asn Leu 130 135 140 Phe Ser Trp Lys Asn Cys Leu Ser Glu Ser Gly Gly Ser His Leu Pro 145 150 155 160 Val His Asp Gly Ser Asp Ala Val Val Ile Asn Val Gly Glu Lys Gly 165 170 175 Ala Ala Gln Arg Arg Ile His Val Asn Gly Asp Ala Gly His Gly Ser 180 185 190 Ile Pro Phe Asp Arg Asp Ser Ala Ile Val Lys Ile Gly Glu Val Ala 195 200 205 Arg Arg Ile Ala Ala Ala Asp Leu Lys Val Ala Lys Asp Asp Ile Trp 210 215 220 Gln Gly Phe Val Gln Ala His Arg Phe Asp Pro Glu Thr Glu Gln Ala 225 230 235 240 Leu Leu Ser Gly Thr Ser Pro Glu Ala Tyr Ala Glu Phe Gly Gly Leu 245 250 255 Ser Arg Phe Ala His Ala Val Ser His Leu Thr Ile Ala Gln Thr Val 260 265 270 Val Arg Ala Gly Gln Ala Ile Asn Val Leu Pro Ser His Ala Tyr Leu 275 280 285 Glu Leu Asp Ile Arg Thr Leu Pro Gly Gln Thr Asn Asp Tyr Val Asp 290 295 300 Asp Thr Leu Arg Ala Ala Leu Gly Asp Leu Ala Asp Glu Val Glu Ile 305 310 315 320 Glu His Leu Ile Ser Glu Glu Ala Thr Val Ser Pro Thr Asp Ser Arg 325 330 335 Leu Tyr Asn Thr Leu Glu Lys Val Leu Gly Asp Phe Phe Pro Asp Ala 340 345 350 Pro Val Val Pro Ile Ile Ser Ser Gly Gly Ser Asp Leu Arg Phe Gly 355 360 365 Arg Arg Leu Gly Gly Val Gly Tyr Gly Phe Ala Val His Ala Arg Glu 370 375 380 Arg Thr Leu Ala Glu Ala Met Gly Gln Leu His Ser His Asp Glu Ala 385 390 395 400 Leu Tyr Leu Glu Asp Leu Glu Leu Thr Val Arg Gly Tyr Asp Ser Val 405 410 415 Val Arg Glu Phe Leu Gly 420 <210> 373 <211> 525 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(502) <223> RXS02937 <400> 373 gctaccgcga agaactgtac tagttcttcc atcagcaccc gcagttgtct ttgcaagagt 60 tcgaaacatc caacgcattg gtgacaccgg tgttgtcgcg gtg atc agc aat ggg 115 Val Ile Ser Asn Gly 1 5 gaa ggt ccg gtt gtt gcg ctt cgt ggc gac att gat gcg ttg ccc atg 163 Glu Gly Pro Val Val Ala Leu Arg Gly Asp Ile Asp Ala Leu Pro Met 10 15 20 gcg gag cga tcc ggc aaa gaa tac gca gca acc gga gtg aca cag gtg 211 Ala Glu Arg Ser Gly Lys Glu Tyr Ala Ala Thr Gly Val Thr Gln Val 25 30 35 gat aac acc acc ggt caa gaa act ccg gtg gcg cat acc tgt ggc cac 259 Asp Asn Thr Thr Gly Gln Glu Thr Pro Val Ala His Thr Cys Gly His 40 45 50 gat gtg cat att tca tca ctg ttg ggt gcg gtg cag gcg ttc aat tct 307 Asp Val His Ile Ser Ser Leu Leu Gly Ala Val Gln Ala Phe Asn Ser 55 60 65 cat cgg gaa ttg tgg aac gga acg ttg atg gcc gtt ttc cag cca gcg 355 His Arg Glu Leu Trp Asn Gly Thr Leu Met Ala Val Phe Gln Pro Ala 70 75 80 85 gaa gag acg gca gct ggt gcg agg atg atg gcg gat cag gac aac gcg 403 Glu Glu Thr Ala Ala Gly Ala Arg Met Met Ala Asp Gln Asp Asn Ala 90 95 100 ccg gga aat cac tct cca gcg ttc gcg cca gat atg cag cca act ctt 451 Pro Gly Asn His Ser Pro Ala Phe Ala Pro Asp Met Gln Pro Thr Leu 105 110 115 gat cgt ggt gtg gaa gcg ctg gtt gta gct gct tct gcg tgg cta gta 499 Asp Arg Gly Val Glu Ala Leu Val Val Ala Ala Ser Ala Trp Leu Val 120 125 130 aaa taattggcta atgaatcctt ttc 525 Lys <210> 374 <211> 134 <212> PRT <213> Corynebacterium glutamicum <400> 374 Val Ile Ser Asn Gly Glu Gly Pro Val Val Ala Leu Arg Gly Asp Ile 1 5 10 15 Asp Ala Leu Pro Met Ala Glu Arg Ser Gly Lys Glu Tyr Ala Ala Thr 20 25 30 Gly Val Thr Gln Val Asp Asn Thr Thr Gly Gln Glu Thr Pro Val Ala 35 40 45 His Thr Cys Gly His Asp Val His Ile Ser Ser Leu Leu Gly Ala Val 50 55 60 Gln Ala Phe Asn Ser His Arg Glu Leu Trp Asn Gly Thr Leu Met Ala 65 70 75 80 Val Phe Gln Pro Ala Glu Glu Thr Ala Ala Gly Ala Arg Met Met Ala 85 90 95 Asp Gln Asp Asn Ala Pro Gly Asn His Ser Pro Ala Phe Ala Pro Asp 100 105 110 Met Gln Pro Thr Leu Asp Arg Gly Val Glu Ala Leu Val Val Ala Ala 115 120 125 Ser Ala Trp Leu Val Lys 130 <210> 375 <211> 966 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(943) <223> RXA02194 <400> 375 gaaatctccc agctcattta ttggacccag gtcatcatgg ttgctcgcgg cctgaagcca 60 gaagatatct acaagaacct gtaggagttt taaagcaatc atg ttg aaa atc gct 115 Met Leu Lys Ile Ala 1 5 gtc cca aac aaa ggc tcg ctg tcc gag cgc gcc atg gaa atc ctc gcc 163 Val Pro Asn Lys Gly Ser Leu Ser Glu Arg Ala Met Glu Ile Leu Ala 10 15 20 gaa gca ggc tac gca ggc cgt gga gat tcc aaa tcc ctc aac gtt ttt 211 Glu Ala Gly Tyr Ala Gly Arg Gly Asp Ser Lys Ser Leu Asn Val Phe 25 30 35 gat gaa gca aac aac gtt gaa ttc ttc ttc ctt cgc cct aaa gat atc 259 Asp Glu Ala Asn Asn Val Glu Phe Phe Phe Leu Arg Pro Lys Asp Ile 40 45 50 gcc atc tac gtt gct ggt ggc cag ctc gat ttg ggt atc acc ggc cgc 307 Ala Ile Tyr Val Ala Gly Gly Gln Leu Asp Leu Gly Ile Thr Gly Arg 55 60 65 gac ctt gct cgc gat tcc cag gct gat gtc cac gaa gtt ctt tcc ctc 355 Asp Leu Ala Arg Asp Ser Gln Ala Asp Val His Glu Val Leu Ser Leu 70 75 80 85 ggc ttc ggt tcc tcc act ttc cgt tac gca gca cca gct gat gaa gag 403 Gly Phe Gly Ser Ser Thr Phe Arg Tyr Ala Ala Pro Ala Asp Glu Glu 90 95 100 tgg agc atc gaa aag ctc gac ggc aag cgc atc gct acc tct tac ccc 451 Trp Ser Ile Glu Lys Leu Asp Gly Lys Arg Ile Ala Thr Ser Tyr Pro 105 110 115 aac ctt gtt cgc gat gac ctc gca gca cgt ggg ctt tcc gct gag gtg 499 Asn Leu Val Arg Asp Asp Leu Ala Ala Arg Gly Leu Ser Ala Glu Val 120 125 130 ctc cgc ctc gac ggt gca gta gag gta tcc atc aag ctt ggt gtc gca 547 Leu Arg Leu Asp Gly Ala Val Glu Val Ser Ile Lys Leu Gly Val Ala 135 140 145 gat gcc atc gcc gat gtt gta tcc acc ggc cgc acg ctg cgt cag caa 595 Asp Ala Ile Ala Asp Val Val Ser Thr Gly Arg Thr Leu Arg Gln Gln 150 155 160 165 ggt ctt gca cct ttc ggc gag gtt ctg tgc acc tct gag gct gtc att 643 Gly Leu Ala Pro Phe Gly Glu Val Leu Cys Thr Ser Glu Ala Val Ile 170 175 180 gtt ggc cgc aag gat gaa aag gtc acc cca gag cag cag atc ctg ctt 691 Val Gly Arg Lys Asp Glu Lys Val Thr Pro Glu Gln Gln Ile Leu Leu 185 190 195 cgc cgc atc cag gga att ttg cac gcg cag aac ttc ctc atg ctg gat 739 Arg Arg Ile Gln Gly Ile Leu His Ala Gln Asn Phe Leu Met Leu Asp 200 205 210 tac aac gtc gac cgc gac aac ctg gac gct gcc act gca gta acc cca 787 Tyr Asn Val Asp Arg Asp Asn Leu Asp Ala Ala Thr Ala Val Thr Pro 215 220 225 ggc tta tcc ggc cca acg gta tcc cca ctg gca cgc gac aac tgg gtt 835 Gly Leu Ser Gly Pro Thr Val Ser Pro Leu Ala Arg Asp Asn Trp Val 230 235 240 245 gct gta cgc gcc atg gtg cca cgc agg tca gct aac gcc atc atg gat 883 Ala Val Arg Ala Met Val Pro Arg Arg Ser Ala Asn Ala Ile Met Asp 250 255 260 aag ctt gct gga ctc ggc gct gaa gcc atc ctg gct tct gaa atc cgc 931 Lys Leu Ala Gly Leu Gly Ala Glu Ala Ile Leu Ala Ser Glu Ile Arg 265 270 275 atc gcc cgc atc tagttttaac tacccccgaa aat 966 Ile Ala Arg Ile 280 <210> 376 <211> 281 <212> PRT <213> Corynebacterium glutamicum <400> 376 Met Leu Lys Ile Ala Val Pro Asn Lys Gly Ser Leu Ser Glu Arg Ala 1 5 10 15 Met Glu Ile Leu Ala Glu Ala Gly Tyr Ala Gly Arg Gly Asp Ser Lys 20 25 30 Ser Leu Asn Val Phe Asp Glu Ala Asn Asn Val Glu Phe Phe Phe Leu 35 40 45 Arg Pro Lys Asp Ile Ala Ile Tyr Val Ala Gly Gly Gln Leu Asp Leu 50 55 60 Gly Ile Thr Gly Arg Asp Leu Ala Arg Asp Ser Gln Ala Asp Val His 65 70 75 80 Glu Val Leu Ser Leu Gly Phe Gly Ser Ser Thr Phe Arg Tyr Ala Ala 85 90 95 Pro Ala Asp Glu Glu Trp Ser Ile Glu Lys Leu Asp Gly Lys Arg Ile 100 105 110 Ala Thr Ser Tyr Pro Asn Leu Val Arg Asp Asp Leu Ala Ala Arg Gly 115 120 125 Leu Ser Ala Glu Val Leu Arg Leu Asp Gly Ala Val Glu Val Ser Ile 130 135 140 Lys Leu Gly Val Ala Asp Ala Ile Ala Asp Val Val Ser Thr Gly Arg 145 150 155 160 Thr Leu Arg Gln Gln Gly Leu Ala Pro Phe Gly Glu Val Leu Cys Thr 165 170 175 Ser Glu Ala Val Ile Val Gly Arg Lys Asp Glu Lys Val Thr Pro Glu 180 185 190 Gln Gln Ile Leu Leu Arg Arg Ile Gln Gly Ile Leu His Ala Gln Asn 195 200 205 Phe Leu Met Leu Asp Tyr Asn Val Asp Arg Asp Asn Leu Asp Ala Ala 210 215 220 Thr Ala Val Thr Pro Gly Leu Ser Gly Pro Thr Val Ser Pro Leu Ala 225 230 235 240 Arg Asp Asn Trp Val Ala Val Arg Ala Met Val Pro Arg Arg Ser Ala 245 250 255 Asn Ala Ile Met Asp Lys Leu Ala Gly Leu Gly Ala Glu Ala Ile Leu 260 265 270 Ala Ser Glu Ile Arg Ile Ala Arg Ile 275 280 <210> 377 <211> 393 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(370) <223> RXA02195 <400> 377 tcgagccggc aggtgtcgca aaataaaacc aggtggggga gtgaaattat tcgactaata 60 tcctccccca aacacacatt gataactgtt gtgtggaaga atg tac cga gtg aag 115 Met Tyr Arg Val Lys 1 5 aca ttt gac tcg ctg tac gaa gaa ctt ctt aac cgt gct cag acc cgc 163 Thr Phe Asp Ser Leu Tyr Glu Glu Leu Leu Asn Arg Ala Gln Thr Arg 10 15 20 cct gaa ggg tct gga acc gtg gcc gcc ttg gat aaa ggc atc cat cat 211 Pro Glu Gly Ser Gly Thr Val Ala Ala Leu Asp Lys Gly Ile His His 25 30 35 cta ggt aag aag gtc atc gaa gaa gcc gga gag gtc tgg att gca gcc 259 Leu Gly Lys Lys Val Ile Glu Glu Ala Gly Glu Val Trp Ile Ala Ala 40 45 50 gag tat gag acc gat gaa gag cta gcc gga gaa atc tcc cag ctc att 307 Glu Tyr Glu Thr Asp Glu Glu Leu Ala Gly Glu Ile Ser Gln Leu Ile 55 60 65 tat tgg acc cag gtc atc atg gtt gct cgc ggc ctg aag cca gaa gat 355 Tyr Trp Thr Gln Val Ile Met Val Ala Arg Gly Leu Lys Pro Glu Asp 70 75 80 85 atc tac aag aac ctg taggagtttt aaagcaatca tgt 393 Ile Tyr Lys Asn Leu 90 <210> 378 <211> 90 <212> PRT <213> Corynebacterium glutamicum <400> 378 Met Tyr Arg Val Lys Thr Phe Asp Ser Leu Tyr Glu Glu Leu Leu Asn 1 5 10 15 Arg Ala Gln Thr Arg Pro Glu Gly Ser Gly Thr Val Ala Ala Leu Asp 20 25 30 Lys Gly Ile His His Leu Gly Lys Lys Val Ile Glu Glu Ala Gly Glu 35 40 45 Val Trp Ile Ala Ala Glu Tyr Glu Thr Asp Glu Glu Leu Ala Gly Glu 50 55 60 Ile Ser Gln Leu Ile Tyr Trp Thr Gln Val Ile Met Val Ala Arg Gly 65 70 75 80 Leu Lys Pro Glu Asp Ile Tyr Lys Asn Leu 85 90 <210> 379 <211> 477 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(454) <223> RXA01097 <400> 379 gcgccaacgc agtgcttgcc gcgaccattt tccacttccg cgaagtaacc atcgccgaag 60 taaagggagc cattaaagat gcaggatttg aggtgcggaa atg agt gac aat cca 115 Met Ser Asp Asn Pro 1 5 caa gag tat gag ctg gat tgg gac gtc gaa aag cga tta aag ctt aac 163 Gln Glu Tyr Glu Leu Asp Trp Asp Val Glu Lys Arg Leu Lys Leu Asn 10 15 20 gac gcc ggc ctg gtg ccg gca atc gtc cag gcc gac ggg acc aac gag 211 Asp Ala Gly Leu Val Pro Ala Ile Val Gln Ala Asp Gly Thr Asn Glu 25 30 35 gtc ctc atg atg gcc tgg atg gat acc cac gcg cta gcc tat act ttg 259 Val Leu Met Met Ala Trp Met Asp Thr His Ala Leu Ala Tyr Thr Leu 40 45 50 gcg acc cgc cgt gga acc tat ttt tct agg tcc cgc aac gag tac tgg 307 Ala Thr Arg Arg Gly Thr Tyr Phe Ser Arg Ser Arg Asn Glu Tyr Trp 55 60 65 atc aag ggc ctg acc tct gga aac gtc caa gaa gtc acc gga ctt gcc 355 Ile Lys Gly Leu Thr Ser Gly Asn Val Gln Glu Val Thr Gly Leu Ala 70 75 80 85 ctc gac tgc gac ggc gac acc gtc ctt ctg acc gtg aaa caa acc ggc 403 Leu Asp Cys Asp Gly Asp Thr Val Leu Leu Thr Val Lys Gln Thr Gly 90 95 100 ggt gcg tgc cac act ggt gcc cac aca tgt ttc gac aat gac gtt ttg 451 Gly Ala Cys His Thr Gly Ala His Thr Cys Phe Asp Asn Asp Val Leu 105 110 115 ctg taaaagcaac aacgattaag gaa 477 Leu <210> 380 <211> 118 <212> PRT <213> Corynebacterium glutamicum <400> 380 Met Ser Asp Asn Pro Gln Glu Tyr Glu Leu Asp Trp Asp Val Glu Lys 1 5 10 15 Arg Leu Lys Leu Asn Asp Ala Gly Leu Val Pro Ala Ile Val Gln Ala 20 25 30 Asp Gly Thr Asn Glu Val Leu Met Met Ala Trp Met Asp Thr His Ala 35 40 45 Leu Ala Tyr Thr Leu Ala Thr Arg Arg Gly Thr Tyr Phe Ser Arg Ser 50 55 60 Arg Asn Glu Tyr Trp Ile Lys Gly Leu Thr Ser Gly Asn Val Gln Glu 65 70 75 80 Val Thr Gly Leu Ala Leu Asp Cys Asp Gly Asp Thr Val Leu Leu Thr 85 90 95 Val Lys Gln Thr Gly Gly Ala Cys His Thr Gly Ala His Thr Cys Phe 100 105 110 Asp Asn Asp Val Leu Leu 115 <210> 381 <211> 861 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(838) <223> RXA01100 <400> 381 gctgtgggct actcaattcc acccagaaaa atcaggtgac gcaggcgcac agctactgcg 60 aaactggatc aactacatct aacagatagg atcaatattc atg acc ttc act att 115 Met Thr Phe Thr Ile 1 5 ctt cct gca gtc gat gta gtt aac gga caa gca gtt cgc cta gat cag 163 Leu Pro Ala Val Asp Val Val Asn Gly Gln Ala Val Arg Leu Asp Gln 10 15 20 ggc gag gcc ggc act gaa aag tct tat ggc acc cct ttg gaa tcc gca 211 Gly Glu Ala Gly Thr Glu Lys Ser Tyr Gly Thr Pro Leu Glu Ser Ala 25 30 35 ctg aag tgg cag gag cag ggt gca aag tgg ttg cac ttt gtg gac ctg 259 Leu Lys Trp Gln Glu Gln Gly Ala Lys Trp Leu His Phe Val Asp Leu 40 45 50 gac gca gcg ttc aac cgt ggt tcc aac cat gag atg atg gcg gaa att 307 Asp Ala Ala Phe Asn Arg Gly Ser Asn His Glu Met Met Ala Glu Ile 55 60 65 gtc ggc aag ctc gat gtt gat gtg gag ctc act ggc ggt atc cgt gat 355 Val Gly Lys Leu Asp Val Asp Val Glu Leu Thr Gly Gly Ile Arg Asp 70 75 80 85 gat gag tct ctg gag cgc gcg ctg gca acc ggt gca cgt cgt gta aac 403 Asp Glu Ser Leu Glu Arg Ala Leu Ala Thr Gly Ala Arg Arg Val Asn 90 95 100 att ggt acc gct gct ctg gag aag cca gag tgg att gct tct gcg att 451 Ile Gly Thr Ala Ala Leu Glu Lys Pro Glu Trp Ile Ala Ser Ala Ile 105 110 115 caa cgc tat ggc gag aag att gct gtc gat atc gct gtg cgt ttg gaa 499 Gln Arg Tyr Gly Glu Lys Ile Ala Val Asp Ile Ala Val Arg Leu Glu 120 125 130 gat ggt gaa tgg cgc acc cgt gga aac ggt tgg gtc tcc gat ggt ggc 547 Asp Gly Glu Trp Arg Thr Arg Gly Asn Gly Trp Val Ser Asp Gly Gly 135 140 145 gat ctg tgg gaa gtt ctc gag cgt ttg gat tcc caa ggt tgt gca cgt 595 Asp Leu Trp Glu Val Leu Glu Arg Leu Asp Ser Gln Gly Cys Ala Arg 150 155 160 165 ttc gtg gtt acc gat gtg tcc aag gac ggc acc ttg agt ggt cca aat 643 Phe Val Val Thr Asp Val Ser Lys Asp Gly Thr Leu Ser Gly Pro Asn 170 175 180 gtt gag ctg ctg cgt gag gtt gct gca gct aca gac gca cct atc gtg 691 Val Glu Leu Leu Arg Glu Val Ala Ala Ala Thr Asp Ala Pro Ile Val 185 190 195 gca tct ggt gga att tct gtt ttg gaa gat gtt ttg gaa cta gcc aag 739 Ala Ser Gly Gly Ile Ser Val Leu Glu Asp Val Leu Glu Leu Ala Lys 200 205 210 tac cag gat gag ggc att gat tcc gtc atc att ggc aag gca ctt tat 787 Tyr Gln Asp Glu Gly Ile Asp Ser Val Ile Ile Gly Lys Ala Leu Tyr 215 220 225 gag cac aag ttc acc ctc gaa gag gct ttg gct gca gta gaa aag ctc 835 Glu His Lys Phe Thr Leu Glu Glu Ala Leu Ala Ala Val Glu Lys Leu 230 235 240 245 ggt taatacatgg atgctcgtgg gat 861 Gly <210> 382 <211> 246 <212> PRT <213> Corynebacterium glutamicum <400> 382 Met Thr Phe Thr Ile Leu Pro Ala Val Asp Val Val Asn Gly Gln Ala 1 5 10 15 Val Arg Leu Asp Gln Gly Glu Ala Gly Thr Glu Lys Ser Tyr Gly Thr 20 25 30 Pro Leu Glu Ser Ala Leu Lys Trp Gln Glu Gln Gly Ala Lys Trp Leu 35 40 45 His Phe Val Asp Leu Asp Ala Ala Phe Asn Arg Gly Ser Asn His Glu 50 55 60 Met Met Ala Glu Ile Val Gly Lys Leu Asp Val Asp Val Glu Leu Thr 65 70 75 80 Gly Gly Ile Arg Asp Asp Glu Ser Leu Glu Arg Ala Leu Ala Thr Gly 85 90 95 Ala Arg Arg Val Asn Ile Gly Thr Ala Ala Leu Glu Lys Pro Glu Trp 100 105 110 Ile Ala Ser Ala Ile Gln Arg Tyr Gly Glu Lys Ile Ala Val Asp Ile 115 120 125 Ala Val Arg Leu Glu Asp Gly Glu Trp Arg Thr Arg Gly Asn Gly Trp 130 135 140 Val Ser Asp Gly Gly Asp Leu Trp Glu Val Leu Glu Arg Leu Asp Ser 145 150 155 160 Gln Gly Cys Ala Arg Phe Val Val Thr Asp Val Ser Lys Asp Gly Thr 165 170 175 Leu Ser Gly Pro Asn Val Glu Leu Leu Arg Glu Val Ala Ala Ala Thr 180 185 190 Asp Ala Pro Ile Val Ala Ser Gly Gly Ile Ser Val Leu Glu Asp Val 195 200 205 Leu Glu Leu Ala Lys Tyr Gln Asp Glu Gly Ile Asp Ser Val Ile Ile 210 215 220 Gly Lys Ala Leu Tyr Glu His Lys Phe Thr Leu Glu Glu Ala Leu Ala 225 230 235 240 Ala Val Glu Lys Leu Gly 245 <210> 383 <211> 756 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(733) <223> RXA01101 <400> 383 atcgcagcta ggccagtgtg gtggatataa aacccttttg gggagaaaga aactcgactg 60 cggttcttga tcctgaaagc acgtgacata aactatcggc atg acc aaa act gtc 115 Met Thr Lys Thr Val 1 5 gcc ctt ctc gac tac gga tct gga aac ctt cgt tct gct caa cgc gca 163 Ala Leu Leu Asp Tyr Gly Ser Gly Asn Leu Arg Ser Ala Gln Arg Ala 10 15 20 cta gag cgt gcc ggt gca gaa gtt atc gtg agc tcc gat cca gaa gtt 211 Leu Glu Arg Ala Gly Ala Glu Val Ile Val Ser Ser Asp Pro Glu Val 25 30 35 tgc acc aac gct gat ggc ctc cta gtt cct gga gtg ggc gca ttt gat 259 Cys Thr Asn Ala Asp Gly Leu Leu Val Pro Gly Val Gly Ala Phe Asp 40 45 50 gcc tgc atg aag ggt ttg aaa aac gtc ttc gga cat cgc att atc gga 307 Ala Cys Met Lys Gly Leu Lys Asn Val Phe Gly His Arg Ile Ile Gly 55 60 65 cag cgt ctt gct ggt gga cgt cca gtg atg ggt att tgt gtg ggc atg 355 Gln Arg Leu Ala Gly Gly Arg Pro Val Met Gly Ile Cys Val Gly Met 70 75 80 85 cag atc ctg ttc gat gaa ggc gat gag cac ggc att aag tca gct ggt 403 Gln Ile Leu Phe Asp Glu Gly Asp Glu His Gly Ile Lys Ser Ala Gly 90 95 100 tgc ggc gag tgg cct ggc aaa gtg gaa cgc ctc caa gcg gag atc ctg 451 Cys Gly Glu Trp Pro Gly Lys Val Glu Arg Leu Gln Ala Glu Ile Leu 105 110 115 cct cac atg ggg tgg aac aca ctt gaa atg cct acc aac tca cca atg 499 Pro His Met Gly Trp Asn Thr Leu Glu Met Pro Thr Asn Ser Pro Met 120 125 130 ttt gag gga att tca cct gat gag cgt ttc tac ttc gtg cac tcc tat 547 Phe Glu Gly Ile Ser Pro Asp Glu Arg Phe Tyr Phe Val His Ser Tyr 135 140 145 ggt gtg cgc aag tgg acg ttg gaa acc gac gat ctg acc acg cct cca 595 Gly Val Arg Lys Trp Thr Leu Glu Thr Asp Asp Leu Thr Thr Pro Pro 150 155 160 165 gag gtt gtg tgg gcg aag cac gaa aat gat cgt ttt gtg gca gct gtg 643 Glu Val Val Trp Ala Lys His Glu Asn Asp Arg Phe Val Ala Ala Val 170 175 180 gaa aac ggc acg ctg tgg gct act caa ttc cac cca gaa aaa tca ggt 691 Glu Asn Gly Thr Leu Trp Ala Thr Gln Phe His Pro Glu Lys Ser Gly 185 190 195 gac gca ggc gca cag cta ctg cga aac tgg atc aac tac atc 733 Asp Ala Gly Ala Gln Leu Leu Arg Asn Trp Ile Asn Tyr Ile 200 205 210 taacagatag gatcaatatt cat 756 <210> 384 <211> 211 <212> PRT <213> Corynebacterium glutamicum <400> 384 Met Thr Lys Thr Val Ala Leu Leu Asp Tyr Gly Ser Gly Asn Leu Arg 1 5 10 15 Ser Ala Gln Arg Ala Leu Glu Arg Ala Gly Ala Glu Val Ile Val Ser 20 25 30 Ser Asp Pro Glu Val Cys Thr Asn Ala Asp Gly Leu Leu Val Pro Gly 35 40 45 Val Gly Ala Phe Asp Ala Cys Met Lys Gly Leu Lys Asn Val Phe Gly 50 55 60 His Arg Ile Ile Gly Gln Arg Leu Ala Gly Gly Arg Pro Val Met Gly 65 70 75 80 Ile Cys Val Gly Met Gln Ile Leu Phe Asp Glu Gly Asp Glu His Gly 85 90 95 Ile Lys Ser Ala Gly Cys Gly Glu Trp Pro Gly Lys Val Glu Arg Leu 100 105 110 Gln Ala Glu Ile Leu Pro His Met Gly Trp Asn Thr Leu Glu Met Pro 115 120 125 Thr Asn Ser Pro Met Phe Glu Gly Ile Ser Pro Asp Glu Arg Phe Tyr 130 135 140 Phe Val His Ser Tyr Gly Val Arg Lys Trp Thr Leu Glu Thr Asp Asp 145 150 155 160 Leu Thr Thr Pro Pro Glu Val Val Trp Ala Lys His Glu Asn Asp Arg 165 170 175 Phe Val Ala Ala Val Glu Asn Gly Thr Leu Trp Ala Thr Gln Phe His 180 185 190 Pro Glu Lys Ser Gly Asp Ala Gly Ala Gln Leu Leu Arg Asn Trp Ile 195 200 205 Asn Tyr Ile 210 <210> 385 <211> 723 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(700) <223> RXN01657 <400> 385 cctccgtcat tgccgacgta tcccgcggcc tgggtgaagc catggtgggc atcaacgtat 60 ccgacgttcc agcaccacac cgactcgccg agcgcggctg gtg atc gtt gga gtt 115 Val Ile Val Gly Val 1 5 tta gct ctc cag ggc ggg gtg gaa gaa cac ctc acc gcc ttg gaa gct 163 Leu Ala Leu Gln Gly Gly Val Glu Glu His Leu Thr Ala Leu Glu Ala 10 15 20 ctc gga gcg acg acc cga aaa gta cgt gtg cca aag gac ctt gat ggt 211 Leu Gly Ala Thr Thr Arg Lys Val Arg Val Pro Lys Asp Leu Asp Gly 25 30 35 ctc gaa ggc atc gtc atc ccc ggc ggg gaa tcc acc gtg ttg gac aaa 259 Leu Glu Gly Ile Val Ile Pro Gly Gly Glu Ser Thr Val Leu Asp Lys 40 45 50 ctg gct cgg aca ttc gac gtg gta gaa cct cta gcg aat ctc att cgc 307 Leu Ala Arg Thr Phe Asp Val Val Glu Pro Leu Ala Asn Leu Ile Arg 55 60 65 gac ggc cta ccc gtt ttc gct acc tgc gct ggc ctg atc tat ctg gcg 355 Asp Gly Leu Pro Val Phe Ala Thr Cys Ala Gly Leu Ile Tyr Leu Ala 70 75 80 85 aaa cac ctc gac aac cca gca agg gga caa caa acc ttg gcg gta gtg 403 Lys His Leu Asp Asn Pro Ala Arg Gly Gln Gln Thr Leu Ala Val Val 90 95 100 gac gtg gtg gtg cgt cga aac gca ttt ggc gcc caa cgc gaa tcc ttc 451 Asp Val Val Val Arg Arg Asn Ala Phe Gly Ala Gln Arg Glu Ser Phe 105 110 115 gac acc acc gtg gat gtt tcc ttc gac ggt gca aca ttc ccc gga gtg 499 Asp Thr Thr Val Asp Val Ser Phe Asp Gly Ala Thr Phe Pro Gly Val 120 125 130 cag gcc tcg ttt atc cga gct ccc atc gtc act gct ttt ggt cct acg 547 Gln Ala Ser Phe Ile Arg Ala Pro Ile Val Thr Ala Phe Gly Pro Thr 135 140 145 gta gaa gcg atc gct gct ctc aac ggt ggg gag gtg gtt ggt gta cgc 595 Val Glu Ala Ile Ala Ala Leu Asn Gly Gly Glu Val Val Gly Val Arg 150 155 160 165 caa ggc aac atc atc gcg ctg tct ttc cat ccc gaa gaa acc ggc gat 643 Gln Gly Asn Ile Ile Ala Leu Ser Phe His Pro Glu Glu Thr Gly Asp 170 175 180 tac cgc atc cac caa gcc tgg ctg gac ctg gtg aga aaa cac gct gaa 691 Tyr Arg Ile His Gln Ala Trp Leu Asp Leu Val Arg Lys His Ala Glu 185 190 195 ctg gcg att tgatgttttc ggtagcgctc tgt 723 Leu Ala Ile 200 <210> 386 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 386 Val Ile Val Gly Val Leu Ala Leu Gln Gly Gly Val Glu Glu His Leu 1 5 10 15 Thr Ala Leu Glu Ala Leu Gly Ala Thr Thr Arg Lys Val Arg Val Pro 20 25 30 Lys Asp Leu Asp Gly Leu Glu Gly Ile Val Ile Pro Gly Gly Glu Ser 35 40 45 Thr Val Leu Asp Lys Leu Ala Arg Thr Phe Asp Val Val Glu Pro Leu 50 55 60 Ala Asn Leu Ile Arg Asp Gly Leu Pro Val Phe Ala Thr Cys Ala Gly 65 70 75 80 Leu Ile Tyr Leu Ala Lys His Leu Asp Asn Pro Ala Arg Gly Gln Gln 85 90 95 Thr Leu Ala Val Val Asp Val Val Val Arg Arg Asn Ala Phe Gly Ala 100 105 110 Gln Arg Glu Ser Phe Asp Thr Thr Val Asp Val Ser Phe Asp Gly Ala 115 120 125 Thr Phe Pro Gly Val Gln Ala Ser Phe Ile Arg Ala Pro Ile Val Thr 130 135 140 Ala Phe Gly Pro Thr Val Glu Ala Ile Ala Ala Leu Asn Gly Gly Glu 145 150 155 160 Val Val Gly Val Arg Gln Gly Asn Ile Ile Ala Leu Ser Phe His Pro 165 170 175 Glu Glu Thr Gly Asp Tyr Arg Ile His Gln Ala Trp Leu Asp Leu Val 180 185 190 Arg Lys His Ala Glu Leu Ala Ile 195 200 <210> 387 <211> 601 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(601) <223> FRXA01657 <400> 387 cctccgtcat tgccgacgta tcccgcggcc tgggtgaagc catggtgggc atcaacgtat 60 ccgacgttcc agcaccacac cgactcgccg agcgcggctg gtg atc gtt gga gtt 115 Val Ile Val Gly Val 1 5 tta gct ctc cag ggc ggg gtg gaa gaa cac ctc acc gcc ttg gaa gct 163 Leu Ala Leu Gln Gly Gly Val Glu Glu His Leu Thr Ala Leu Glu Ala 10 15 20 ctc gga gcg acg acc cga aaa gta cgt gtg cca aag gac ctt gat ggt 211 Leu Gly Ala Thr Thr Arg Lys Val Arg Val Pro Lys Asp Leu Asp Gly 25 30 35 ctc gaa ggc atc gtc atc ccc ggc ggg gaa tcc acc gtg ttg gac aaa 259 Leu Glu Gly Ile Val Ile Pro Gly Gly Glu Ser Thr Val Leu Asp Lys 40 45 50 ctg gct cgg aca ttc gac gtg gta gaa cct cta gcg aat ctc att cgc 307 Leu Ala Arg Thr Phe Asp Val Val Glu Pro Leu Ala Asn Leu Ile Arg 55 60 65 gac ggc cta ccc gtt ttc gct acc tgc gct ggc ctg atc tat ctg gcg 355 Asp Gly Leu Pro Val Phe Ala Thr Cys Ala Gly Leu Ile Tyr Leu Ala 70 75 80 85 aaa cac ctc gac aac cca gca agg gga caa caa acc ttg gcg gta gtg 403 Lys His Leu Asp Asn Pro Ala Arg Gly Gln Gln Thr Leu Ala Val Val 90 95 100 gac gtg gtg gtg cgt cga aac gca ttt ggc gcc caa cgc gaa tcc ttc 451 Asp Val Val Val Arg Arg Asn Ala Phe Gly Ala Gln Arg Glu Ser Phe 105 110 115 gac acc acc gtg gat gtt tcc ttc gac ggt gca aca ttc ccc gga gtg 499 Asp Thr Thr Val Asp Val Ser Phe Asp Gly Ala Thr Phe Pro Gly Val 120 125 130 cag gcc tcg ttt atc cga gct ccc atc gtc act gct ttt ggt cct acg 547 Gln Ala Ser Phe Ile Arg Ala Pro Ile Val Thr Ala Phe Gly Pro Thr 135 140 145 gta gaa gcg atc gct gct ctc aac ggt ggg gag gtg gtt ggt gta cgc 595 Val Glu Ala Ile Ala Ala Leu Asn Gly Gly Glu Val Val Gly Val Arg 150 155 160 165 caa ggc 601 Gln Gly <210> 388 <211> 167 <212> PRT <213> Corynebacterium glutamicum <400> 388 Val Ile Val Gly Val Leu Ala Leu Gln Gly Gly Val Glu Glu His Leu 1 5 10 15 Thr Ala Leu Glu Ala Leu Gly Ala Thr Thr Arg Lys Val Arg Val Pro 20 25 30 Lys Asp Leu Asp Gly Leu Glu Gly Ile Val Ile Pro Gly Gly Glu Ser 35 40 45 Thr Val Leu Asp Lys Leu Ala Arg Thr Phe Asp Val Val Glu Pro Leu 50 55 60 Ala Asn Leu Ile Arg Asp Gly Leu Pro Val Phe Ala Thr Cys Ala Gly 65 70 75 80 Leu Ile Tyr Leu Ala Lys His Leu Asp Asn Pro Ala Arg Gly Gln Gln 85 90 95 Thr Leu Ala Val Val Asp Val Val Val Arg Arg Asn Ala Phe Gly Ala 100 105 110 Gln Arg Glu Ser Phe Asp Thr Thr Val Asp Val Ser Phe Asp Gly Ala 115 120 125 Thr Phe Pro Gly Val Gln Ala Ser Phe Ile Arg Ala Pro Ile Val Thr 130 135 140 Ala Phe Gly Pro Thr Val Glu Ala Ile Ala Ala Leu Asn Gly Gly Glu 145 150 155 160 Val Val Gly Val Arg Gln Gly 165 <210> 389 <211> 897 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(874) <223> RXA01098 <400> 389 aaaagggctc acgatgtgct gttaagtaag attgaaaaag ttcggttgat gcatgcagat 60 gcaggtaatg accagtcgtt aaatgaggag tacaagtaaa atg ggc gtg gca att 115 Met Gly Val Ala Ile 1 5 cga gtt att cct tgc ctg gac gtg gac aac ggc cgg gtt gtt aaa ggc 163 Arg Val Ile Pro Cys Leu Asp Val Asp Asn Gly Arg Val Val Lys Gly 10 15 20 gtg aac ttt gaa aac ctc cgc gat gct ggc gat cct gtg gag ttg gca 211 Val Asn Phe Glu Asn Leu Arg Asp Ala Gly Asp Pro Val Glu Leu Ala 25 30 35 aag cgc tat gac gag gaa ggg gca gat gag ctg acc ttc ctg gat gtc 259 Lys Arg Tyr Asp Glu Glu Gly Ala Asp Glu Leu Thr Phe Leu Asp Val 40 45 50 acc gcc tcg aag cat ggt cgc ggc acc atg ctg gat gtt gtt cga cgc 307 Thr Ala Ser Lys His Gly Arg Gly Thr Met Leu Asp Val Val Arg Arg 55 60 65 acc gct gat cag gtg ttc atc cct ctg act gtc ggt ggc ggc gtg cgc 355 Thr Ala Asp Gln Val Phe Ile Pro Leu Thr Val Gly Gly Gly Val Arg 70 75 80 85 agc gaa gaa gat gtt gat caa ttg ctg cgc gct ggc gcc gac aag gtt 403 Ser Glu Glu Asp Val Asp Gln Leu Leu Arg Ala Gly Ala Asp Lys Val 90 95 100 tcg gtg aac acg tct gcg att gcc cgt cca gaa ctg ctg tca gag ctg 451 Ser Val Asn Thr Ser Ala Ile Ala Arg Pro Glu Leu Leu Ser Glu Leu 105 110 115 tcc aag cgt ttt ggt gct cag tgc atc gtg ttg tct gtg gat gcc agg 499 Ser Lys Arg Phe Gly Ala Gln Cys Ile Val Leu Ser Val Asp Ala Arg 120 125 130 cgc gtt cct gaa ggt gga act cct cag cca tct ggt ttt gaa gtc acc 547 Arg Val Pro Glu Gly Gly Thr Pro Gln Pro Ser Gly Phe Glu Val Thr 135 140 145 acc cac ggc ggt tcc aag tcc gca gaa ctt gat gca atc gag tgg gca 595 Thr His Gly Gly Ser Lys Ser Ala Glu Leu Asp Ala Ile Glu Trp Ala 150 155 160 165 aag cgc ggc gaa gag ctg ggc gtt ggc gaa att ctg ctc aac tcc atg 643 Lys Arg Gly Glu Glu Leu Gly Val Gly Glu Ile Leu Leu Asn Ser Met 170 175 180 gac ggc gac ggc acc aaa aac ggc ttt gac cta gag ctg ctg gaa aaa 691 Asp Gly Asp Gly Thr Lys Asn Gly Phe Asp Leu Glu Leu Leu Glu Lys 185 190 195 gtt cgc gca gcc gta tcc att cct gta atc gcc tcc ggc ggc gct ggc 739 Val Arg Ala Ala Val Ser Ile Pro Val Ile Ala Ser Gly Gly Ala Gly 200 205 210 aag gcg gag cat ttc cca cca gct gtt gca gct ggc gcc aac gca gtg 787 Lys Ala Glu His Phe Pro Pro Ala Val Ala Ala Gly Ala Asn Ala Val 215 220 225 ctt gcc gcg acc att ttc cac ttc cgc gaa gta acc atc gcc gaa gta 835 Leu Ala Ala Thr Ile Phe His Phe Arg Glu Val Thr Ile Ala Glu Val 230 235 240 245 aag gga gcc att aaa gat gca gga ttt gag gtg cgg aaa tgagtgacaa 884 Lys Gly Ala Ile Lys Asp Ala Gly Phe Glu Val Arg Lys 250 255 tccacaagag tat 897 <210> 390 <211> 258 <212> PRT <213> Corynebacterium glutamicum <400> 390 Met Gly Val Ala Ile Arg Val Ile Pro Cys Leu Asp Val Asp Asn Gly 1 5 10 15 Arg Val Val Lys Gly Val Asn Phe Glu Asn Leu Arg Asp Ala Gly Asp 20 25 30 Pro Val Glu Leu Ala Lys Arg Tyr Asp Glu Glu Gly Ala Asp Glu Leu 35 40 45 Thr Phe Leu Asp Val Thr Ala Ser Lys His Gly Arg Gly Thr Met Leu 50 55 60 Asp Val Val Arg Arg Thr Ala Asp Gln Val Phe Ile Pro Leu Thr Val 65 70 75 80 Gly Gly Gly Val Arg Ser Glu Glu Asp Val Asp Gln Leu Leu Arg Ala 85 90 95 Gly Ala Asp Lys Val Ser Val Asn Thr Ser Ala Ile Ala Arg Pro Glu 100 105 110 Leu Leu Ser Glu Leu Ser Lys Arg Phe Gly Ala Gln Cys Ile Val Leu 115 120 125 Ser Val Asp Ala Arg Arg Val Pro Glu Gly Gly Thr Pro Gln Pro Ser 130 135 140 Gly Phe Glu Val Thr Thr His Gly Gly Ser Lys Ser Ala Glu Leu Asp 145 150 155 160 Ala Ile Glu Trp Ala Lys Arg Gly Glu Glu Leu Gly Val Gly Glu Ile 165 170 175 Leu Leu Asn Ser Met Asp Gly Asp Gly Thr Lys Asn Gly Phe Asp Leu 180 185 190 Glu Leu Leu Glu Lys Val Arg Ala Ala Val Ser Ile Pro Val Ile Ala 195 200 205 Ser Gly Gly Ala Gly Lys Ala Glu His Phe Pro Pro Ala Val Ala Ala 210 215 220 Gly Ala Asn Ala Val Leu Ala Ala Thr Ile Phe His Phe Arg Glu Val 225 230 235 240 Thr Ile Ala Glu Val Lys Gly Ala Ile Lys Asp Ala Gly Phe Glu Val 245 250 255 Arg Lys <210> 391 <211> 729 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(706) <223> RXN01104 <400> 391 cacttgcgca ctaccattgg tgtgcctgag gaaaatgatg cgtttttgga cgcagctgca 60 gagatcatca agctgaacct gtaagagaga agaatttttc atg act gtc gca cca 115 Met Thr Val Ala Pro 1 5 aga att ggt acc gca acc cgc acc acc agc gaa tcc gac atc acc gtc 163 Arg Ile Gly Thr Ala Thr Arg Thr Thr Ser Glu Ser Asp Ile Thr Val 10 15 20 gag atc aac ctg gac ggc acc ggc aaa gta gat atc gat acc ggc ctg 211 Glu Ile Asn Leu Asp Gly Thr Gly Lys Val Asp Ile Asp Thr Gly Leu 25 30 35 cca ttt ttc gac cac atg ctc act gca ttc ggc gtg cac ggc agt ttt 259 Pro Phe Phe Asp His Met Leu Thr Ala Phe Gly Val His Gly Ser Phe 40 45 50 gat ctg aaa gtc cat gcc aag ggc gac atc gag atc gac gca cac cac 307 Asp Leu Lys Val His Ala Lys Gly Asp Ile Glu Ile Asp Ala His His 55 60 65 acc gtg gaa gat acc gcc atc gtg ctc ggc caa gca ctc ctt gac gct 355 Thr Val Glu Asp Thr Ala Ile Val Leu Gly Gln Ala Leu Leu Asp Ala 70 75 80 85 att ggc gac aag aaa ggc atc cgc cgt ttc gca tcc tgc cag ctg ccc 403 Ile Gly Asp Lys Lys Gly Ile Arg Arg Phe Ala Ser Cys Gln Leu Pro 90 95 100 atg gat gag gca tta gtg gag tcc gtg gtg gat atc tcc ggt cgc cca 451 Met Asp Glu Ala Leu Val Glu Ser Val Val Asp Ile Ser Gly Arg Pro 105 110 115 tac ttc gtg atc tcc ggc gaa cca gac cac atg atc acc tcc gtg atc 499 Tyr Phe Val Ile Ser Gly Glu Pro Asp His Met Ile Thr Ser Val Ile 120 125 130 ggt gga cac tac gca acc gtg atc aac gag cac ttc ttt gaa acc ctc 547 Gly Gly His Tyr Ala Thr Val Ile Asn Glu His Phe Phe Glu Thr Leu 135 140 145 gcg ctc aac tcc cga atc acc ctc cac gtg atc tgc cac tac ggc cgc 595 Ala Leu Asn Ser Arg Ile Thr Leu His Val Ile Cys His Tyr Gly Arg 150 155 160 165 gac cct cac cac atc acc gaa gca gag tac aag gct gtt gcc cgt gcg 643 Asp Pro His His Ile Thr Glu Ala Glu Tyr Lys Ala Val Ala Arg Ala 170 175 180 ctg cgc ggt gcc gta gag atg gat cct cgt caa aca gga atc cca tcc 691 Leu Arg Gly Ala Val Glu Met Asp Pro Arg Gln Thr Gly Ile Pro Ser 185 190 195 act aag gga gcg ctc tagacatgaa ctcttctccc atc 729 Thr Lys Gly Ala Leu 200 <210> 392 <211> 202 <212> PRT <213> Corynebacterium glutamicum <400> 392 Met Thr Val Ala Pro Arg Ile Gly Thr Ala Thr Arg Thr Thr Ser Glu 1 5 10 15 Ser Asp Ile Thr Val Glu Ile Asn Leu Asp Gly Thr Gly Lys Val Asp 20 25 30 Ile Asp Thr Gly Leu Pro Phe Phe Asp His Met Leu Thr Ala Phe Gly 35 40 45 Val His Gly Ser Phe Asp Leu Lys Val His Ala Lys Gly Asp Ile Glu 50 55 60 Ile Asp Ala His His Thr Val Glu Asp Thr Ala Ile Val Leu Gly Gln 65 70 75 80 Ala Leu Leu Asp Ala Ile Gly Asp Lys Lys Gly Ile Arg Arg Phe Ala 85 90 95 Ser Cys Gln Leu Pro Met Asp Glu Ala Leu Val Glu Ser Val Val Asp 100 105 110 Ile Ser Gly Arg Pro Tyr Phe Val Ile Ser Gly Glu Pro Asp His Met 115 120 125 Ile Thr Ser Val Ile Gly Gly His Tyr Ala Thr Val Ile Asn Glu His 130 135 140 Phe Phe Glu Thr Leu Ala Leu Asn Ser Arg Ile Thr Leu His Val Ile 145 150 155 160 Cys His Tyr Gly Arg Asp Pro His His Ile Thr Glu Ala Glu Tyr Lys 165 170 175 Ala Val Ala Arg Ala Leu Arg Gly Ala Val Glu Met Asp Pro Arg Gln 180 185 190 Thr Gly Ile Pro Ser Thr Lys Gly Ala Leu 195 200 <210> 393 <211> 729 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(706) <223> FRXA01104 <400> 393 cacttgcgca ctaccattgg tgtgcctgag gaaaatgatg cgtttttgga cgcagctgca 60 gagatcatca agctgaacct gtaagagaga agaatttttc atg act gtc gca cca 115 Met Thr Val Ala Pro 1 5 aga att ggt acc gca acc cgc acc acc agc gaa tcc gac atc acc gtc 163 Arg Ile Gly Thr Ala Thr Arg Thr Thr Ser Glu Ser Asp Ile Thr Val 10 15 20 gag atc aac ctg gac ggc acc ggc aaa gta gat atc gat acc ggc ctg 211 Glu Ile Asn Leu Asp Gly Thr Gly Lys Val Asp Ile Asp Thr Gly Leu 25 30 35 cca ttt ttc gac cac atg ctc act gca ttc ggc gtg cac ggc agt ttt 259 Pro Phe Phe Asp His Met Leu Thr Ala Phe Gly Val His Gly Ser Phe 40 45 50 gat ctg aaa gtc cat gcc aag ggc gac atc gag atc gac gca cac cac 307 Asp Leu Lys Val His Ala Lys Gly Asp Ile Glu Ile Asp Ala His His 55 60 65 acc gtg gaa gat acc gcc atc gtg ctc ggc caa gca ctc ctt gac gct 355 Thr Val Glu Asp Thr Ala Ile Val Leu Gly Gln Ala Leu Leu Asp Ala 70 75 80 85 att ggc gac aag aaa ggc atc cgc cgt ttc gca tcc tgc cag ctg ccc 403 Ile Gly Asp Lys Lys Gly Ile Arg Arg Phe Ala Ser Cys Gln Leu Pro 90 95 100 atg gat gag gca tta gtg gag tcc gtg gtg gat atc tcc ggt cgc cca 451 Met Asp Glu Ala Leu Val Glu Ser Val Val Asp Ile Ser Gly Arg Pro 105 110 115 tac ttc gtg atc tcc ggc gaa cca gac cac atg atc acc tcc gtg atc 499 Tyr Phe Val Ile Ser Gly Glu Pro Asp His Met Ile Thr Ser Val Ile 120 125 130 ggt gga cac tac gca acc gtg atc aac gag cac ttc ttt gaa acc ctc 547 Gly Gly His Tyr Ala Thr Val Ile Asn Glu His Phe Phe Glu Thr Leu 135 140 145 gcg ctc aac tcc cga atc acc ctc cac gtg atc tgc cac tac ggc cgc 595 Ala Leu Asn Ser Arg Ile Thr Leu His Val Ile Cys His Tyr Gly Arg 150 155 160 165 gac cct cac cac atc acc gaa gca gag tac aag gct gtt gcc cgt gcg 643 Asp Pro His His Ile Thr Glu Ala Glu Tyr Lys Ala Val Ala Arg Ala 170 175 180 ctg cgc ggt gcc gta gag atg gat cct cgt caa aca gga atc cca tcc 691 Leu Arg Gly Ala Val Glu Met Asp Pro Arg Gln Thr Gly Ile Pro Ser 185 190 195 act aag gga gcg ctc tagacatgaa ctcttctccc atc 729 Thr Lys Gly Ala Leu 200 <210> 394 <211> 202 <212> PRT <213> Corynebacterium glutamicum <400> 394 Met Thr Val Ala Pro Arg Ile Gly Thr Ala Thr Arg Thr Thr Ser Glu 1 5 10 15 Ser Asp Ile Thr Val Glu Ile Asn Leu Asp Gly Thr Gly Lys Val Asp 20 25 30 Ile Asp Thr Gly Leu Pro Phe Phe Asp His Met Leu Thr Ala Phe Gly 35 40 45 Val His Gly Ser Phe Asp Leu Lys Val His Ala Lys Gly Asp Ile Glu 50 55 60 Ile Asp Ala His His Thr Val Glu Asp Thr Ala Ile Val Leu Gly Gln 65 70 75 80 Ala Leu Leu Asp Ala Ile Gly Asp Lys Lys Gly Ile Arg Arg Phe Ala 85 90 95 Ser Cys Gln Leu Pro Met Asp Glu Ala Leu Val Glu Ser Val Val Asp 100 105 110 Ile Ser Gly Arg Pro Tyr Phe Val Ile Ser Gly Glu Pro Asp His Met 115 120 125 Ile Thr Ser Val Ile Gly Gly His Tyr Ala Thr Val Ile Asn Glu His 130 135 140 Phe Phe Glu Thr Leu Ala Leu Asn Ser Arg Ile Thr Leu His Val Ile 145 150 155 160 Cys His Tyr Gly Arg Asp Pro His His Ile Thr Glu Ala Glu Tyr Lys 165 170 175 Ala Val Ala Arg Ala Leu Arg Gly Ala Val Glu Met Asp Pro Arg Gln 180 185 190 Thr Gly Ile Pro Ser Thr Lys Gly Ala Leu 195 200 <210> 395 <211> 987 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(964) <223> RXN00446 <400> 395 tgctacgaag ttatctagta atgaagttag tttttcccct ctcccggcag cagttgatgc 60 ggtgacggag gctacttggg gggctaatcg gtacccggat atg ggt gcg gtt gag 115 Met Gly Ala Val Glu 1 5 ctc cgt gag gct ctt gca gag cat tta gag gtt gag ttt gac cag gtc 163 Leu Arg Glu Ala Leu Ala Glu His Leu Glu Val Glu Phe Asp Gln Val 10 15 20 acg gta ggt tgc ggc tcg tct gcg ctg tgt caa cag ctg gtt cag gca 211 Thr Val Gly Cys Gly Ser Ser Ala Leu Cys Gln Gln Leu Val Gln Ala 25 30 35 acg tgc gct cag ggc gat gag gtc att ttt cca tgg cgc agc ttt gag 259 Thr Cys Ala Gln Gly Asp Glu Val Ile Phe Pro Trp Arg Ser Phe Glu 40 45 50 gct tat cca att ttc gcg cag gtc gcg ggc gcc act cct gtt gcc att 307 Ala Tyr Pro Ile Phe Ala Gln Val Ala Gly Ala Thr Pro Val Ala Ile 55 60 65 ccg ctg act gct gat cag aat cat gat ctt gat gcg atg gca gcc gcg 355 Pro Leu Thr Ala Asp Gln Asn His Asp Leu Asp Ala Met Ala Ala Ala 70 75 80 85 atc act gat aag acc cgc ctc att ttc atc tgc aac ccc aac aat cct 403 Ile Thr Asp Lys Thr Arg Leu Ile Phe Ile Cys Asn Pro Asn Asn Pro 90 95 100 tcg ggc acc acc atc acc cag gcg cag ttt gat aat ttc atg gaa aag 451 Ser Gly Thr Thr Ile Thr Gln Ala Gln Phe Asp Asn Phe Met Glu Lys 105 110 115 gtt cca aac gat gtc gtt gtt ggg ctg gat gag gct tat ttt gag ttc 499 Val Pro Asn Asp Val Val Val Gly Leu Asp Glu Ala Tyr Phe Glu Phe 120 125 130 aac cgc gcg gac gac acc cca gtt gcc act gag gaa atc cac cgc cac 547 Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu Glu Ile His Arg His 135 140 145 gac aac gtg att ggt ttg cgc acg ttc tcc aag gcg tat ggc ctg gcg 595 Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys Ala Tyr Gly Leu Ala 150 155 160 165 ggc ttg cgt gtt ggt tac gcc ttc gga aac gca gag atc atc gca gcg 643 Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala Glu Ile Ile Ala Ala 170 175 180 atg aat aag gtg gct att cct ttc gcg gtg aat tca gca gct cag gcg 691 Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn Ser Ala Ala Gln Ala 185 190 195 gca gcg ctt gcg agt ttg aat tct gcc gat gag ttg atg gaa cgg gtg 739 Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu Leu Met Glu Arg Val 200 205 210 gag gaa acc gtc gaa aag cgt gat gct gtg gtg tca gcg ctt ggt gct 787 Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val Ser Ala Leu Gly Ala 215 220 225 gcg ccg acg cag gcc aat ttc gtc tgg ctg ccg ggc gag ggc gcc gct 835 Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro Gly Glu Gly Ala Ala 230 235 240 245 gag ttg gcg gct aaa ttg gcc gag cac ggc atc gtg att cgc gcg ttc 883 Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile Val Ile Arg Ala Phe 250 255 260 ccc gag ggt gcg cgc att tcg gtg acc aac gcc gag gaa act gac aag 931 Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala Glu Glu Thr Asp Lys 265 270 275 ctg ctg cgc gcg tgg gag gcc atc aat gct ggg tagtctttgg cgttttgcgg 984 Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 280 285 tgc 987 <210> 396 <211> 288 <212> PRT <213> Corynebacterium glutamicum <400> 396 Met Gly Ala Val Glu Leu Arg Glu Ala Leu Ala Glu His Leu Glu Val 1 5 10 15 Glu Phe Asp Gln Val Thr Val Gly Cys Gly Ser Ser Ala Leu Cys Gln 20 25 30 Gln Leu Val Gln Ala Thr Cys Ala Gln Gly Asp Glu Val Ile Phe Pro 35 40 45 Trp Arg Ser Phe Glu Ala Tyr Pro Ile Phe Ala Gln Val Ala Gly Ala 50 55 60 Thr Pro Val Ala Ile Pro Leu Thr Ala Asp Gln Asn His Asp Leu Asp 65 70 75 80 Ala Met Ala Ala Ala Ile Thr Asp Lys Thr Arg Leu Ile Phe Ile Cys 85 90 95 Asn Pro Asn Asn Pro Ser Gly Thr Thr Ile Thr Gln Ala Gln Phe Asp 100 105 110 Asn Phe Met Glu Lys Val Pro Asn Asp Val Val Val Gly Leu Asp Glu 115 120 125 Ala Tyr Phe Glu Phe Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu 130 135 140 Glu Ile His Arg His Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys 145 150 155 160 Ala Tyr Gly Leu Ala Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala 165 170 175 Glu Ile Ile Ala Ala Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn 180 185 190 Ser Ala Ala Gln Ala Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu 195 200 205 Leu Met Glu Arg Val Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val 210 215 220 Ser Ala Leu Gly Ala Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro 225 230 235 240 Gly Glu Gly Ala Ala Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile 245 250 255 Val Ile Arg Ala Phe Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala 260 265 270 Glu Glu Thr Asp Lys Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 275 280 285 <210> 397 <211> 545 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(522) <223> FRXA00446 <400> 397 atg gaa aag gtt cca aac gat gtc gtt gtt ggg ctg gat gag gct tat 48 Met Glu Lys Val Pro Asn Asp Val Val Val Gly Leu Asp Glu Ala Tyr 1 5 10 15 ttt gag ttc aac cgc gcg gac gac acc cca gtt gcc act gag gaa atc 96 Phe Glu Phe Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu Glu Ile 20 25 30 cac cgc cac gac aac gtg att ggt ttg cgc acg ttc tcc aag gcg tat 144 His Arg His Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys Ala Tyr 35 40 45 ggc ctg gcg ggc ttg cgt gtt ggt tac gcc ttc gga aac gca gag atc 192 Gly Leu Ala Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala Glu Ile 50 55 60 atc gca gcg atg aat aag gtg gct att cct ttc gcg gtg aat tca gca 240 Ile Ala Ala Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn Ser Ala 65 70 75 80 gct cag gcg gca gcg ctt gcg agt ttg aat tct gcc gat gag ttg atg 288 Ala Gln Ala Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu Leu Met 85 90 95 gaa cgg gtg gag gaa acc gtc gaa aag cgt gat gct gtg gtg tca gcg 336 Glu Arg Val Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val Ser Ala 100 105 110 ctt ggt gct gcg ccg acg cag gcc aat ttc gtc tgg ctg ccg ggc gag 384 Leu Gly Ala Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro Gly Glu 115 120 125 ggc gcc gct gag ttg gcg gct aaa ttg gcc gag cac ggc atc gtg att 432 Gly Ala Ala Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile Val Ile 130 135 140 cgc gcg ttc ccc gag ggt gcg cgc att tcg gtg acc aac gcc gag gaa 480 Arg Ala Phe Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala Glu Glu 145 150 155 160 act gac aag ctg ctg cgc gcg tgg gag gcc atc aat gct ggg 522 Thr Asp Lys Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 165 170 tagtctttgg cgttttgcgg tgc 545 <210> 398 <211> 174 <212> PRT <213> Corynebacterium glutamicum <400> 398 Met Glu Lys Val Pro Asn Asp Val Val Val Gly Leu Asp Glu Ala Tyr 1 5 10 15 Phe Glu Phe Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu Glu Ile 20 25 30 His Arg His Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys Ala Tyr 35 40 45 Gly Leu Ala Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala Glu Ile 50 55 60 Ile Ala Ala Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn Ser Ala 65 70 75 80 Ala Gln Ala Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu Leu Met 85 90 95 Glu Arg Val Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val Ser Ala 100 105 110 Leu Gly Ala Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro Gly Glu 115 120 125 Gly Ala Ala Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile Val Ile 130 135 140 Arg Ala Phe Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala Glu Glu 145 150 155 160 Thr Asp Lys Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 165 170 <210> 399 <211> 1221 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1198) <223> RXA01105 <400> 399 ttgtcatcaa ctttgccaac gccgaagatc ttccagcgca cggcgaagca atccgtgcac 60 gctttgaaaa cctccccacc accgacgagg cctaagaaaa atg acc aaa att act 115 Met Thr Lys Ile Thr 1 5 ttg agc gat ttg cca ttg cgt gaa gaa ctg cgc ggt gag cac gct tac 163 Leu Ser Asp Leu Pro Leu Arg Glu Glu Leu Arg Gly Glu His Ala Tyr 10 15 20 ggc gca ccc cag ctc aac gtt gat att cgc ctc aac acc aac gaa aac 211 Gly Ala Pro Gln Leu Asn Val Asp Ile Arg Leu Asn Thr Asn Glu Asn 25 30 35 cct tac cca ccg tca gag gca ttg gtc gct gac ttg gtt gcc acc gtg 259 Pro Tyr Pro Pro Ser Glu Ala Leu Val Ala Asp Leu Val Ala Thr Val 40 45 50 gat aag atc gcc acc gag ctg aac cgc tac cca gag cgc gat gct gtg 307 Asp Lys Ile Ala Thr Glu Leu Asn Arg Tyr Pro Glu Arg Asp Ala Val 55 60 65 gaa ctg cgt gat gag ttg gct gcg tac atc acc aag caa acc ggc gtg 355 Glu Leu Arg Asp Glu Leu Ala Ala Tyr Ile Thr Lys Gln Thr Gly Val 70 75 80 85 gct gtc acc agg gat aac ctg tgg gct gcc aat ggt tcc aat gaa att 403 Ala Val Thr Arg Asp Asn Leu Trp Ala Ala Asn Gly Ser Asn Glu Ile 90 95 100 ctg cag cag ctg ctg cag gct ttt ggt gga cct gga cgc acc gcg ttg 451 Leu Gln Gln Leu Leu Gln Ala Phe Gly Gly Pro Gly Arg Thr Ala Leu 105 110 115 gga ttc caa ccc agc tat tcc atg cac cca att ttg gct aaa ggc acc 499 Gly Phe Gln Pro Ser Tyr Ser Met His Pro Ile Leu Ala Lys Gly Thr 120 125 130 cac act gaa ttc att gcg gtg tcc cga ggt gct gat ttc cgc atc gat 547 His Thr Glu Phe Ile Ala Val Ser Arg Gly Ala Asp Phe Arg Ile Asp 135 140 145 atg gat gtg gcg ctg gaa gaa att cgt gca aag cag cct gac att gtt 595 Met Asp Val Ala Leu Glu Glu Ile Arg Ala Lys Gln Pro Asp Ile Val 150 155 160 165 ttt gtc acc acc ccg aac aac ccg acc ggt gat gtg acc tcg ctg gac 643 Phe Val Thr Thr Pro Asn Asn Pro Thr Gly Asp Val Thr Ser Leu Asp 170 175 180 gat gtt gag cgc atc atc aac gtt gcc cca ggc atc gtg atc gtg gat 691 Asp Val Glu Arg Ile Ile Asn Val Ala Pro Gly Ile Val Ile Val Asp 185 190 195 gaa gct tat gcg gaa ttc tcc cca tca cct tca gca acc act ctt ctg 739 Glu Ala Tyr Ala Glu Phe Ser Pro Ser Pro Ser Ala Thr Thr Leu Leu 200 205 210 gag aag tac cca acc aag ctg gtg gtg tcc cgc acc atg agt aag gct 787 Glu Lys Tyr Pro Thr Lys Leu Val Val Ser Arg Thr Met Ser Lys Ala 215 220 225 ttt gat ttc gca ggt gga cgc ctc ggc tac ttc gtg gcc aac cca gcg 835 Phe Asp Phe Ala Gly Gly Arg Leu Gly Tyr Phe Val Ala Asn Pro Ala 230 235 240 245 ttt atc gac gcc gtg atg cta gtc cgc ctt ccg tat cat ctt tca gcg 883 Phe Ile Asp Ala Val Met Leu Val Arg Leu Pro Tyr His Leu Ser Ala 250 255 260 ctg agc caa gca gcc gca atc gta gcg ctg cgt cac tcc gct gac acg 931 Leu Ser Gln Ala Ala Ala Ile Val Ala Leu Arg His Ser Ala Asp Thr 265 270 275 ctg gga acc gtc gaa aag ctc tct gta gag cgt gtt cgc gtg gca gca 979 Leu Gly Thr Val Glu Lys Leu Ser Val Glu Arg Val Arg Val Ala Ala 280 285 290 cgc ttg gag gaa ctg ggc tac gct gtg gtt cca agt gag tcc aac ttt 1027 Arg Leu Glu Glu Leu Gly Tyr Ala Val Val Pro Ser Glu Ser Asn Phe 295 300 305 gtg ttc ttt gga gat ttc tcc gat cag cac gcg gca tgg cag gca ttt 1075 Val Phe Phe Gly Asp Phe Ser Asp Gln His Ala Ala Trp Gln Ala Phe 310 315 320 325 ttg gat agg gga gtg ctc atc cgc gat gtg gga atc gct ggg cac ttg 1123 Leu Asp Arg Gly Val Leu Ile Arg Asp Val Gly Ile Ala Gly His Leu 330 335 340 cgc act acc att ggt gtg cct gag gaa aat gat gcg ttt ttg gac gca 1171 Arg Thr Thr Ile Gly Val Pro Glu Glu Asn Asp Ala Phe Leu Asp Ala 345 350 355 gct gca gag atc atc aag ctg aac ctg taagagagaa gaatttttca 1218 Ala Ala Glu Ile Ile Lys Leu Asn Leu 360 365 tga 1221 <210> 400 <211> 366 <212> PRT <213> Corynebacterium glutamicum <400> 400 Met Thr Lys Ile Thr Leu Ser Asp Leu Pro Leu Arg Glu Glu Leu Arg 1 5 10 15 Gly Glu His Ala Tyr Gly Ala Pro Gln Leu Asn Val Asp Ile Arg Leu 20 25 30 Asn Thr Asn Glu Asn Pro Tyr Pro Pro Ser Glu Ala Leu Val Ala Asp 35 40 45 Leu Val Ala Thr Val Asp Lys Ile Ala Thr Glu Leu Asn Arg Tyr Pro 50 55 60 Glu Arg Asp Ala Val Glu Leu Arg Asp Glu Leu Ala Ala Tyr Ile Thr 65 70 75 80 Lys Gln Thr Gly Val Ala Val Thr Arg Asp Asn Leu Trp Ala Ala Asn 85 90 95 Gly Ser Asn Glu Ile Leu Gln Gln Leu Leu Gln Ala Phe Gly Gly Pro 100 105 110 Gly Arg Thr Ala Leu Gly Phe Gln Pro Ser Tyr Ser Met His Pro Ile 115 120 125 Leu Ala Lys Gly Thr His Thr Glu Phe Ile Ala Val Ser Arg Gly Ala 130 135 140 Asp Phe Arg Ile Asp Met Asp Val Ala Leu Glu Glu Ile Arg Ala Lys 145 150 155 160 Gln Pro Asp Ile Val Phe Val Thr Thr Pro Asn Asn Pro Thr Gly Asp 165 170 175 Val Thr Ser Leu Asp Asp Val Glu Arg Ile Ile Asn Val Ala Pro Gly 180 185 190 Ile Val Ile Val Asp Glu Ala Tyr Ala Glu Phe Ser Pro Ser Pro Ser 195 200 205 Ala Thr Thr Leu Leu Glu Lys Tyr Pro Thr Lys Leu Val Val Ser Arg 210 215 220 Thr Met Ser Lys Ala Phe Asp Phe Ala Gly Gly Arg Leu Gly Tyr Phe 225 230 235 240 Val Ala Asn Pro Ala Phe Ile Asp Ala Val Met Leu Val Arg Leu Pro 245 250 255 Tyr His Leu Ser Ala Leu Ser Gln Ala Ala Ala Ile Val Ala Leu Arg 260 265 270 His Ser Ala Asp Thr Leu Gly Thr Val Glu Lys Leu Ser Val Glu Arg 275 280 285 Val Arg Val Ala Ala Arg Leu Glu Glu Leu Gly Tyr Ala Val Val Pro 290 295 300 Ser Glu Ser Asn Phe Val Phe Phe Gly Asp Phe Ser Asp Gln His Ala 305 310 315 320 Ala Trp Gln Ala Phe Leu Asp Arg Gly Val Leu Ile Arg Asp Val Gly 325 330 335 Ile Ala Gly His Leu Arg Thr Thr Ile Gly Val Pro Glu Glu Asn Asp 340 345 350 Ala Phe Leu Asp Ala Ala Ala Glu Ile Ile Lys Leu Asn Leu 355 360 365 <210> 401 <211> 1449 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1426) <223> RXA01106 <400> 401 ggtaaacatg cgggcttaag aacttgtgtt gaggccgctt ggattcgggc accgagctcg 60 aagaatttcg attcaacctt ttaagggaga acttttcgcc atg ttg aat gtc act 115 Met Leu Asn Val Thr 1 5 gac ctg cga ggt caa aca cca tcc aag agc gac atc cga cgt gct ttg 163 Asp Leu Arg Gly Gln Thr Pro Ser Lys Ser Asp Ile Arg Arg Ala Leu 10 15 20 cca cgt ggt ggc act gac gtg tgg tct gtg ctt ccc ata gtg cag cct 211 Pro Arg Gly Gly Thr Asp Val Trp Ser Val Leu Pro Ile Val Gln Pro 25 30 35 gtt gta gaa gat gtc caa aac cgc ggc gct gaa gct gct ttg gat tac 259 Val Val Glu Asp Val Gln Asn Arg Gly Ala Glu Ala Ala Leu Asp Tyr 40 45 50 ggc gag aag ttc gac cat att cgc ccc gcc tcg gtg cgg gtg cca gct 307 Gly Glu Lys Phe Asp His Ile Arg Pro Ala Ser Val Arg Val Pro Ala 55 60 65 gag gtt att gct gca gca gaa aac acc tta gat ccg ttg gtg cgt gaa 355 Glu Val Ile Ala Ala Ala Glu Asn Thr Leu Asp Pro Leu Val Arg Glu 70 75 80 85 tcg att gaa gag tcg att cgt cgc gtc cgc aag gtt cac gct gag caa 403 Ser Ile Glu Glu Ser Ile Arg Arg Val Arg Lys Val His Ala Glu Gln 90 95 100 aag cca tcc gag cac acc act gaa ctt tca cca ggt ggc acc gtc act 451 Lys Pro Ser Glu His Thr Thr Glu Leu Ser Pro Gly Gly Thr Val Thr 105 110 115 gag cgt ttc atg ccg att gat cgc gtg gga ctg tac gtt cca ggc ggc 499 Glu Arg Phe Met Pro Ile Asp Arg Val Gly Leu Tyr Val Pro Gly Gly 120 125 130 aat gcg gtg tac cca tca agc gtg att atg aat act gtc cca gct caa 547 Asn Ala Val Tyr Pro Ser Ser Val Ile Met Asn Thr Val Pro Ala Gln 135 140 145 gag gct ggt gtg aac tcc ctt gtg gtt gcg tcg cct cct cag gct gag 595 Glu Ala Gly Val Asn Ser Leu Val Val Ala Ser Pro Pro Gln Ala Glu 150 155 160 165 cac ggt ggc tgg cct cac ccc acc att ttg gcg gcg tgt tcc atc ttg 643 His Gly Gly Trp Pro His Pro Thr Ile Leu Ala Ala Cys Ser Ile Leu 170 175 180 ggt gtt gat gag gtg tgg gct gtc ggc ggc ggt cag gcc gtg gcg ttg 691 Gly Val Asp Glu Val Trp Ala Val Gly Gly Gly Gln Ala Val Ala Leu 185 190 195 ctg gct tat ggt gat gac gct gca ggt ctc gag cct gtg gat atg atc 739 Leu Ala Tyr Gly Asp Asp Ala Ala Gly Leu Glu Pro Val Asp Met Ile 200 205 210 act gga cct ggc aat atc ttt gtc acc gct gcg aag cgc ctg gtc agg 787 Thr Gly Pro Gly Asn Ile Phe Val Thr Ala Ala Lys Arg Leu Val Arg 215 220 225 gga gtg gta ggt act gat tct gag gct ggc cct aca gaa atc gct gtg 835 Gly Val Val Gly Thr Asp Ser Glu Ala Gly Pro Thr Glu Ile Ala Val 230 235 240 245 ctt gct gat gcc tct gcc aac gcc gtc aac gtt gcc tac gat ctg atc 883 Leu Ala Asp Ala Ser Ala Asn Ala Val Asn Val Ala Tyr Asp Leu Ile 250 255 260 agc caa gca gaa cac gat gtc atg gct gcg tcc gtg ctc atc act gac 931 Ser Gln Ala Glu His Asp Val Met Ala Ala Ser Val Leu Ile Thr Asp 265 270 275 tcc gag cag ctt gcc aag gac gta aac agg gaa atc gag gcg cgt tac 979 Ser Glu Gln Leu Ala Lys Asp Val Asn Arg Glu Ile Glu Ala Arg Tyr 280 285 290 tca atc acg cgc aac gcc gag cgc gtc gca gaa gct ttg cgc ggg gcc 1027 Ser Ile Thr Arg Asn Ala Glu Arg Val Ala Glu Ala Leu Arg Gly Ala 295 300 305 cag agt ggc atc gtg ctt gtc gac gac att tcc gtg ggt atc caa gta 1075 Gln Ser Gly Ile Val Leu Val Asp Asp Ile Ser Val Gly Ile Gln Val 310 315 320 325 gcc gat caa tac gca gcg gaa cac ctg gaa atc cac act gag aac gcg 1123 Ala Asp Gln Tyr Ala Ala Glu His Leu Glu Ile His Thr Glu Asn Ala 330 335 340 cgc gcc gta gca gag cag atc acc aac gcg ggt gcg atc ttc gtg ggc 1171 Arg Ala Val Ala Glu Gln Ile Thr Asn Ala Gly Ala Ile Phe Val Gly 345 350 355 gat ttc tca cca gta cca ctg ggt gat tac tcc gca gga tcc aac cac 1219 Asp Phe Ser Pro Val Pro Leu Gly Asp Tyr Ser Ala Gly Ser Asn His 360 365 370 gtg ctg cca acc tct gga tcc gct cgt ttc tcc gca ggt cta tcc acg 1267 Val Leu Pro Thr Ser Gly Ser Ala Arg Phe Ser Ala Gly Leu Ser Thr 375 380 385 cac acg ttc ctt cgc cca gtc aac ctc att gaa tac gat gag gct gct 1315 His Thr Phe Leu Arg Pro Val Asn Leu Ile Glu Tyr Asp Glu Ala Ala 390 395 400 405 ctg aag gac gtc tcg cag gtt gtc atc aac ttt gcc aac gcc gaa gat 1363 Leu Lys Asp Val Ser Gln Val Val Ile Asn Phe Ala Asn Ala Glu Asp 410 415 420 ctt cca gcg cac ggc gaa gca atc cgt gca cgc ttt gaa aac ctc ccc 1411 Leu Pro Ala His Gly Glu Ala Ile Arg Ala Arg Phe Glu Asn Leu Pro 425 430 435 acc acc gac gag gcc taagaaaaat gaccaaaatt act 1449 Thr Thr Asp Glu Ala 440 <210> 402 <211> 442 <212> PRT <213> Corynebacterium glutamicum <400> 402 Met Leu Asn Val Thr Asp Leu Arg Gly Gln Thr Pro Ser Lys Ser Asp 1 5 10 15 Ile Arg Arg Ala Leu Pro Arg Gly Gly Thr Asp Val Trp Ser Val Leu 20 25 30 Pro Ile Val Gln Pro Val Val Glu Asp Val Gln Asn Arg Gly Ala Glu 35 40 45 Ala Ala Leu Asp Tyr Gly Glu Lys Phe Asp His Ile Arg Pro Ala Ser 50 55 60 Val Arg Val Pro Ala Glu Val Ile Ala Ala Ala Glu Asn Thr Leu Asp 65 70 75 80 Pro Leu Val Arg Glu Ser Ile Glu Glu Ser Ile Arg Arg Val Arg Lys 85 90 95 Val His Ala Glu Gln Lys Pro Ser Glu His Thr Thr Glu Leu Ser Pro 100 105 110 Gly Gly Thr Val Thr Glu Arg Phe Met Pro Ile Asp Arg Val Gly Leu 115 120 125 Tyr Val Pro Gly Gly Asn Ala Val Tyr Pro Ser Ser Val Ile Met Asn 130 135 140 Thr Val Pro Ala Gln Glu Ala Gly Val Asn Ser Leu Val Val Ala Ser 145 150 155 160 Pro Pro Gln Ala Glu His Gly Gly Trp Pro His Pro Thr Ile Leu Ala 165 170 175 Ala Cys Ser Ile Leu Gly Val Asp Glu Val Trp Ala Val Gly Gly Gly 180 185 190 Gln Ala Val Ala Leu Leu Ala Tyr Gly Asp Asp Ala Ala Gly Leu Glu 195 200 205 Pro Val Asp Met Ile Thr Gly Pro Gly Asn Ile Phe Val Thr Ala Ala 210 215 220 Lys Arg Leu Val Arg Gly Val Val Gly Thr Asp Ser Glu Ala Gly Pro 225 230 235 240 Thr Glu Ile Ala Val Leu Ala Asp Ala Ser Ala Asn Ala Val Asn Val 245 250 255 Ala Tyr Asp Leu Ile Ser Gln Ala Glu His Asp Val Met Ala Ala Ser 260 265 270 Val Leu Ile Thr Asp Ser Glu Gln Leu Ala Lys Asp Val Asn Arg Glu 275 280 285 Ile Glu Ala Arg Tyr Ser Ile Thr Arg Asn Ala Glu Arg Val Ala Glu 290 295 300 Ala Leu Arg Gly Ala Gln Ser Gly Ile Val Leu Val Asp Asp Ile Ser 305 310 315 320 Val Gly Ile Gln Val Ala Asp Gln Tyr Ala Ala Glu His Leu Glu Ile 325 330 335 His Thr Glu Asn Ala Arg Ala Val Ala Glu Gln Ile Thr Asn Ala Gly 340 345 350 Ala Ile Phe Val Gly Asp Phe Ser Pro Val Pro Leu Gly Asp Tyr Ser 355 360 365 Ala Gly Ser Asn His Val Leu Pro Thr Ser Gly Ser Ala Arg Phe Ser 370 375 380 Ala Gly Leu Ser Thr His Thr Phe Leu Arg Pro Val Asn Leu Ile Glu 385 390 395 400 Tyr Asp Glu Ala Ala Leu Lys Asp Val Ser Gln Val Val Ile Asn Phe 405 410 415 Ala Asn Ala Glu Asp Leu Pro Ala His Gly Glu Ala Ile Arg Ala Arg 420 425 430 Phe Glu Asn Leu Pro Thr Thr Asp Glu Ala 435 440 <210> 403 <211> 876 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(853) <223> RXC00930 <400> 403 acggcgcacc acacatttgg tggtgtattg agctatctct gggctgcgtg agaaaccatt 60 ttccggtgga tgatggaagc tagacgacga aagggagcat atg tct ggc cac tca 115 Met Ser Gly His Ser 1 5 aaa tgg gcg act acc aag cac aag aag gct gct aac gac gcc aag cga 163 Lys Trp Ala Thr Thr Lys His Lys Lys Ala Ala Asn Asp Ala Lys Arg 10 15 20 ggc aag gaa ttt gcc aag ctg atc aag aac atc gaa gtt gcg gca cgt 211 Gly Lys Glu Phe Ala Lys Leu Ile Lys Asn Ile Glu Val Ala Ala Arg 25 30 35 aca ggc ggt gga gat ccg tct gcg aac cca acg ctt gat gac atg atc 259 Thr Gly Gly Gly Asp Pro Ser Ala Asn Pro Thr Leu Asp Asp Met Ile 40 45 50 aag aaa gcc aag aag gct tct gtg ccg aac gat aac atc gaa cgt gca 307 Lys Lys Ala Lys Lys Ala Ser Val Pro Asn Asp Asn Ile Glu Arg Ala 55 60 65 cgc aag cgt ggc tcc ggc gaa gaa gct ggt ggc gct gac tgg atg aac 355 Arg Lys Arg Gly Ser Gly Glu Glu Ala Gly Gly Ala Asp Trp Met Asn 70 75 80 85 atc atg tac gag gga tac ggc ccc aac ggc gtt gcc atg ctt atc gag 403 Ile Met Tyr Glu Gly Tyr Gly Pro Asn Gly Val Ala Met Leu Ile Glu 90 95 100 tgt ctg acc gac aac cgt aac cgc gca gct acc gaa gtt cgc acc gca 451 Cys Leu Thr Asp Asn Arg Asn Arg Ala Ala Thr Glu Val Arg Thr Ala 105 110 115 atg acc aaa aac ggt ggc aac ttg ggc gag tcc ggt tcc gtg tcc tac 499 Met Thr Lys Asn Gly Gly Asn Leu Gly Glu Ser Gly Ser Val Ser Tyr 120 125 130 atg ttc acc cgc acc ggt gtc gtc acc gta caa aag ggc gat ctt agt 547 Met Phe Thr Arg Thr Gly Val Val Thr Val Gln Lys Gly Asp Leu Ser 135 140 145 gaa gat gac gtg ctc atg gct gtt ctt gaa gct ggt gct gaa gaa gtc 595 Glu Asp Asp Val Leu Met Ala Val Leu Glu Ala Gly Ala Glu Glu Val 150 155 160 165 aac gac aac ggc gat ctg ttc gag gtt acc tgc gca cca act gac att 643 Asn Asp Asn Gly Asp Leu Phe Glu Val Thr Cys Ala Pro Thr Asp Ile 170 175 180 cag gct gtt cgc gac gca ctc gtg gaa gct ggc att gaa gta gaa gat 691 Gln Ala Val Arg Asp Ala Leu Val Glu Ala Gly Ile Glu Val Glu Asp 185 190 195 tct gaa tca gac ttc cgg gca tct gtt cag gtc ccc ctg gac gct gac 739 Ser Glu Ser Asp Phe Arg Ala Ser Val Gln Val Pro Leu Asp Ala Asp 200 205 210 ggt gca cgc aag atc ttc aag ctt gtg gac gcg ttg gaa gat tcc gac 787 Gly Ala Arg Lys Ile Phe Lys Leu Val Asp Ala Leu Glu Asp Ser Asp 215 220 225 gat gtg caa aac gtc tac acc aac atc gac ttg agc gat gag gtt ttg 835 Asp Val Gln Asn Val Tyr Thr Asn Ile Asp Leu Ser Asp Glu Val Leu 230 235 240 245 aca gag ctg gaa aac gac tagttcgtat tttccgcact ccg 876 Thr Glu Leu Glu Asn Asp 250 <210> 404 <211> 251 <212> PRT <213> Corynebacterium glutamicum <400> 404 Met Ser Gly His Ser Lys Trp Ala Thr Thr Lys His Lys Lys Ala Ala 1 5 10 15 Asn Asp Ala Lys Arg Gly Lys Glu Phe Ala Lys Leu Ile Lys Asn Ile 20 25 30 Glu Val Ala Ala Arg Thr Gly Gly Gly Asp Pro Ser Ala Asn Pro Thr 35 40 45 Leu Asp Asp Met Ile Lys Lys Ala Lys Lys Ala Ser Val Pro Asn Asp 50 55 60 Asn Ile Glu Arg Ala Arg Lys Arg Gly Ser Gly Glu Glu Ala Gly Gly 65 70 75 80 Ala Asp Trp Met Asn Ile Met Tyr Glu Gly Tyr Gly Pro Asn Gly Val 85 90 95 Ala Met Leu Ile Glu Cys Leu Thr Asp Asn Arg Asn Arg Ala Ala Thr 100 105 110 Glu Val Arg Thr Ala Met Thr Lys Asn Gly Gly Asn Leu Gly Glu Ser 115 120 125 Gly Ser Val Ser Tyr Met Phe Thr Arg Thr Gly Val Val Thr Val Gln 130 135 140 Lys Gly Asp Leu Ser Glu Asp Asp Val Leu Met Ala Val Leu Glu Ala 145 150 155 160 Gly Ala Glu Glu Val Asn Asp Asn Gly Asp Leu Phe Glu Val Thr Cys 165 170 175 Ala Pro Thr Asp Ile Gln Ala Val Arg Asp Ala Leu Val Glu Ala Gly 180 185 190 Ile Glu Val Glu Asp Ser Glu Ser Asp Phe Arg Ala Ser Val Gln Val 195 200 205 Pro Leu Asp Ala Asp Gly Ala Arg Lys Ile Phe Lys Leu Val Asp Ala 210 215 220 Leu Glu Asp Ser Asp Asp Val Gln Asn Val Tyr Thr Asn Ile Asp Leu 225 230 235 240 Ser Asp Glu Val Leu Thr Glu Leu Glu Asn Asp 245 250 <210> 405 <211> 547 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(547) <223> RXC01096 <400> 405 accgtgaaac aaaccggcgg tgcgtgccac actggtgccc acacatgttt cgacaatgac 60 gttttgctgt aaaagcaaca acgattaagg aagaaatctt atg aag cca cgc gtg 115 Met Lys Pro Arg Val 1 5 ctg tca gca tta ggc att gga gct ggc gcc ctg gtt gtc tgg atc agc 163 Leu Ser Ala Leu Gly Ile Gly Ala Gly Ala Leu Val Val Trp Ile Ser 10 15 20 tca cgc atg aac tgg gta acc atc gag gct ttc gac gat aaa tca ggt 211 Ser Arg Met Asn Trp Val Thr Ile Glu Ala Phe Asp Asp Lys Ser Gly 25 30 35 agt gtc acc caa tct att gtg ggt gca acc tgg tct aca gaa atc atg 259 Ser Val Thr Gln Ser Ile Val Gly Ala Thr Trp Ser Thr Glu Ile Met 40 45 50 gcg ctt gca ctt gct ttg ctc gct gcc ttc gcc gcc gcg ttg gtg ctc 307 Ala Leu Ala Leu Ala Leu Leu Ala Ala Phe Ala Ala Ala Leu Val Leu 55 60 65 aag cgc atg ggt cgg cgc atc att ggt ggt att tcg gcg ctg atc gcg 355 Lys Arg Met Gly Arg Arg Ile Ile Gly Gly Ile Ser Ala Leu Ile Ala 70 75 80 85 gtg ggt gcc agc ctg tct cca ctc gcg ctt ctc acc caa gac cca gac 403 Val Gly Ala Ser Leu Ser Pro Leu Ala Leu Leu Thr Gln Asp Pro Asp 90 95 100 gca gaa cgg gcc cga acc ctg ctg acc tcc ggt gtg gcc tca cag aag 451 Ala Glu Arg Ala Arg Thr Leu Leu Thr Ser Gly Val Ala Ser Gln Lys 105 110 115 gct aat tcc gga acc ctg ctg tct gat tgg gcg gag atc atc aat acc 499 Ala Asn Ser Gly Thr Leu Leu Ser Asp Trp Ala Glu Ile Ile Asn Thr 120 125 130 acc acc cat cca ctg gcg gca gtg gta gcc atg att ggc tgc gcg cta 547 Thr Thr His Pro Leu Ala Ala Val Val Ala Met Ile Gly Cys Ala Leu 135 140 145 <210> 406 <211> 149 <212> PRT <213> Corynebacterium glutamicum <400> 406 Met Lys Pro Arg Val Leu Ser Ala Leu Gly Ile Gly Ala Gly Ala Leu 1 5 10 15 Val Val Trp Ile Ser Ser Arg Met Asn Trp Val Thr Ile Glu Ala Phe 20 25 30 Asp Asp Lys Ser Gly Ser Val Thr Gln Ser Ile Val Gly Ala Thr Trp 35 40 45 Ser Thr Glu Ile Met Ala Leu Ala Leu Ala Leu Leu Ala Ala Phe Ala 50 55 60 Ala Ala Leu Val Leu Lys Arg Met Gly Arg Arg Ile Ile Gly Gly Ile 65 70 75 80 Ser Ala Leu Ile Ala Val Gly Ala Ser Leu Ser Pro Leu Ala Leu Leu 85 90 95 Thr Gln Asp Pro Asp Ala Glu Arg Ala Arg Thr Leu Leu Thr Ser Gly 100 105 110 Val Ala Ser Gln Lys Ala Asn Ser Gly Thr Leu Leu Ser Asp Trp Ala 115 120 125 Glu Ile Ile Asn Thr Thr Thr His Pro Leu Ala Ala Val Val Ala Met 130 135 140 Ile Gly Cys Ala Leu 145 <210> 407 <211> 1020 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(997) <223> RXC01656 <400> 407 tcggcaagca tggcttcatc gtcctcaaaa aagtggtcta atgcaagtga ctgaaagtgg 60 atctaccgct agtccacttt gtggcgttgg atcatctgtc atg acc gaa act caa 115 Met Thr Glu Thr Gln 1 5 gaa act tac caa gca acc act cgt gtg aag cgc ggc ctt gcc gac atg 163 Glu Thr Tyr Gln Ala Thr Thr Arg Val Lys Arg Gly Leu Ala Asp Met 10 15 20 ctc aag ggt ggt gtg atc atg gat gtg gtc acc cct gaa caa gcg cgc 211 Leu Lys Gly Gly Val Ile Met Asp Val Val Thr Pro Glu Gln Ala Arg 25 30 35 atc gcc gaa gat gca ggt gcc agc gca gtt atg gca ctc gag cgc gtt 259 Ile Ala Glu Asp Ala Gly Ala Ser Ala Val Met Ala Leu Glu Arg Val 40 45 50 ccc gcc gat atc cgt tct cag ggc ggc gtt gct cgc atg agt gat cct 307 Pro Ala Asp Ile Arg Ser Gln Gly Gly Val Ala Arg Met Ser Asp Pro 55 60 65 gac ctg atc gaa gga atc gtc aat gcg gtc tcc atc ccg gtc atg gcg 355 Asp Leu Ile Glu Gly Ile Val Asn Ala Val Ser Ile Pro Val Met Ala 70 75 80 85 aaa gct cgc atc ggt cac ttc gtg gaa gct cag gtt ctg gaa gct ctc 403 Lys Ala Arg Ile Gly His Phe Val Glu Ala Gln Val Leu Glu Ala Leu 90 95 100 ggt gtt gat ttc atc gac gag tcc gaa gtt ctc agc cct gcc gac tac 451 Gly Val Asp Phe Ile Asp Glu Ser Glu Val Leu Ser Pro Ala Asp Tyr 105 110 115 acg cac cac atc aac aag tgg aag ttc gac gtt cct ttc gtc tgt ggc 499 Thr His His Ile Asn Lys Trp Lys Phe Asp Val Pro Phe Val Cys Gly 120 125 130 gcg acc aac ctc ggc gaa gct ttg cga cgc atc acc gaa ggc gct gca 547 Ala Thr Asn Leu Gly Glu Ala Leu Arg Arg Ile Thr Glu Gly Ala Ala 135 140 145 atg atc cgt tcc aag ggc gaa gcc ggc acc ggc gat gtc tct gaa gct 595 Met Ile Arg Ser Lys Gly Glu Ala Gly Thr Gly Asp Val Ser Glu Ala 150 155 160 165 gtc cgt cac ctg cgc acc atc cgc ggc gac atc aat cgc ctg cgc tcc 643 Val Arg His Leu Arg Thr Ile Arg Gly Asp Ile Asn Arg Leu Arg Ser 170 175 180 ctg gat gag gat gaa ctc ttc gtc gcc gcc aag gaa ttc cag gca cca 691 Leu Asp Glu Asp Glu Leu Phe Val Ala Ala Lys Glu Phe Gln Ala Pro 185 190 195 tac gac ctg gtc cgc gaa gtc gcc tcc acc ggc aag ctc cct gtg gtc 739 Tyr Asp Leu Val Arg Glu Val Ala Ser Thr Gly Lys Leu Pro Val Val 200 205 210 acc ttc gtt gca ggt ggc gtc gca acc cca gcc gac gct gca ctc gtg 787 Thr Phe Val Ala Gly Gly Val Ala Thr Pro Ala Asp Ala Ala Leu Val 215 220 225 cgc caa atg ggc gcc gaa ggc gtc ttt gtc ggc tcc ggc atc ttc aaa 835 Arg Gln Met Gly Ala Glu Gly Val Phe Val Gly Ser Gly Ile Phe Lys 230 235 240 245 tcc ggc aat cca gcc gcc cgc gcc gca gcg atc gtc aag gct gca acg 883 Ser Gly Asn Pro Ala Ala Arg Ala Ala Ala Ile Val Lys Ala Ala Thr 250 255 260 ctt ttc gac gac ccc tcc gtc att gcc gac gta tcc cgc ggc ctg ggt 931 Leu Phe Asp Asp Pro Ser Val Ile Ala Asp Val Ser Arg Gly Leu Gly 265 270 275 gaa gcc atg gtg ggc atc aac gta tcc gac gtt cca gca cca cac cga 979 Glu Ala Met Val Gly Ile Asn Val Ser Asp Val Pro Ala Pro His Arg 280 285 290 ctc gcc gag cgc ggc tgg tgatcgttgg agttttagct ctc 1020 Leu Ala Glu Arg Gly Trp 295 <210> 408 <211> 299 <212> PRT <213> Corynebacterium glutamicum <400> 408 Met Thr Glu Thr Gln Glu Thr Tyr Gln Ala Thr Thr Arg Val Lys Arg 1 5 10 15 Gly Leu Ala Asp Met Leu Lys Gly Gly Val Ile Met Asp Val Val Thr 20 25 30 Pro Glu Gln Ala Arg Ile Ala Glu Asp Ala Gly Ala Ser Ala Val Met 35 40 45 Ala Leu Glu Arg Val Pro Ala Asp Ile Arg Ser Gln Gly Gly Val Ala 50 55 60 Arg Met Ser Asp Pro Asp Leu Ile Glu Gly Ile Val Asn Ala Val Ser 65 70 75 80 Ile Pro Val Met Ala Lys Ala Arg Ile Gly His Phe Val Glu Ala Gln 85 90 95 Val Leu Glu Ala Leu Gly Val Asp Phe Ile Asp Glu Ser Glu Val Leu 100 105 110 Ser Pro Ala Asp Tyr Thr His His Ile Asn Lys Trp Lys Phe Asp Val 115 120 125 Pro Phe Val Cys Gly Ala Thr Asn Leu Gly Glu Ala Leu Arg Arg Ile 130 135 140 Thr Glu Gly Ala Ala Met Ile Arg Ser Lys Gly Glu Ala Gly Thr Gly 145 150 155 160 Asp Val Ser Glu Ala Val Arg His Leu Arg Thr Ile Arg Gly Asp Ile 165 170 175 Asn Arg Leu Arg Ser Leu Asp Glu Asp Glu Leu Phe Val Ala Ala Lys 180 185 190 Glu Phe Gln Ala Pro Tyr Asp Leu Val Arg Glu Val Ala Ser Thr Gly 195 200 205 Lys Leu Pro Val Val Thr Phe Val Ala Gly Gly Val Ala Thr Pro Ala 210 215 220 Asp Ala Ala Leu Val Arg Gln Met Gly Ala Glu Gly Val Phe Val Gly 225 230 235 240 Ser Gly Ile Phe Lys Ser Gly Asn Pro Ala Ala Arg Ala Ala Ala Ile 245 250 255 Val Lys Ala Ala Thr Leu Phe Asp Asp Pro Ser Val Ile Ala Asp Val 260 265 270 Ser Arg Gly Leu Gly Glu Ala Met Val Gly Ile Asn Val Ser Asp Val 275 280 285 Pro Ala Pro His Arg Leu Ala Glu Arg Gly Trp 290 295 <210> 409 <211> 1065 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1042) <223> RXC01158 <400> 409 taggacgttc aaggaattgg ctgaatcaac aagcgccaag gtggttaagc gccctcggcg 60 agttatctca aaaaagaaga agaagtctcc tacgggagag atg tcc att gtt gag 115 Met Ser Ile Val Glu 1 5 cac atc aaa gag ttt cga cgc cga ctt ctt atc gct ctg gcg ggc atc 163 His Ile Lys Glu Phe Arg Arg Arg Leu Leu Ile Ala Leu Ala Gly Ile 10 15 20 ctc gtg ggc acc att atc ggc ttt att tgg tac gat ttc tca ttt tgg 211 Leu Val Gly Thr Ile Ile Gly Phe Ile Trp Tyr Asp Phe Ser Phe Trp 25 30 35 cag atc ccc act ttg ggc gag ctg ctg agg gat ccg tac tgt tct ctg 259 Gln Ile Pro Thr Leu Gly Glu Leu Leu Arg Asp Pro Tyr Cys Ser Leu 40 45 50 cct gct gaa tcc cgc tgg gcc atg agc gac tca gag gaa tgt cga ctg 307 Pro Ala Glu Ser Arg Trp Ala Met Ser Asp Ser Glu Glu Cys Arg Leu 55 60 65 ctc gca acc ggc ccg ttt gat cca ttc atg ctt cgc ctt aaa gta gcg 355 Leu Ala Thr Gly Pro Phe Asp Pro Phe Met Leu Arg Leu Lys Val Ala 70 75 80 85 gcg ttg gtg ggt atg gtt ctt ggc tca ccc gtg tgg ctg agc cag ctg 403 Ala Leu Val Gly Met Val Leu Gly Ser Pro Val Trp Leu Ser Gln Leu 90 95 100 tgg ggc ttt atc acc cca ggt ttg atg aag aat gag cgc cgt tac acc 451 Trp Gly Phe Ile Thr Pro Gly Leu Met Lys Asn Glu Arg Arg Tyr Thr 105 110 115 gca atc ttc gtc acg att gct gtt gtg ctg ttt gtc ggc ggt gct gtt 499 Ala Ile Phe Val Thr Ile Ala Val Val Leu Phe Val Gly Gly Ala Val 120 125 130 ctt gcg tac ttc gtc gtt gca tat ggt ttg gag ttc ctc ctt acc att 547 Leu Ala Tyr Phe Val Val Ala Tyr Gly Leu Glu Phe Leu Leu Thr Ile 135 140 145 ggt gga gac acc cag gca gcg gcc ctg act ggt gat aag tac ttc gga 595 Gly Gly Asp Thr Gln Ala Ala Ala Leu Thr Gly Asp Lys Tyr Phe Gly 150 155 160 165 ttc ttg ctc gcg ttg ttg gcg att ttc ggc gtg agc ttc gaa gtt cca 643 Phe Leu Leu Ala Leu Leu Ala Ile Phe Gly Val Ser Phe Glu Val Pro 170 175 180 ctg gtg atc ggc atg ctc aac att gtg ggt atc ttg cct tac gat gcc 691 Leu Val Ile Gly Met Leu Asn Ile Val Gly Ile Leu Pro Tyr Asp Ala 185 190 195 att aaa gat aag cga cgc atg atc atc atg att ttg ttc gtg ttc gct 739 Ile Lys Asp Lys Arg Arg Met Ile Ile Met Ile Leu Phe Val Phe Ala 200 205 210 gct ttc atg aca ccc ggc cag gat cct ttc acc atg ttg gtg ttg gcg 787 Ala Phe Met Thr Pro Gly Gln Asp Pro Phe Thr Met Leu Val Leu Ala 215 220 225 ctt tca ctc acc gtt ctg gta gag ctt gcc ctg cag ttc tgt cgc ttc 835 Leu Ser Leu Thr Val Leu Val Glu Leu Ala Leu Gln Phe Cys Arg Phe 230 235 240 245 aac gac aaa cgc cgg gac aag aag cgc cca gaa tgg ctt gat ggc gat 883 Asn Asp Lys Arg Arg Asp Lys Lys Arg Pro Glu Trp Leu Asp Gly Asp 250 255 260 gac ctc tct gca tca cca ctg gat act tct gct ggt gga gaa gat gct 931 Asp Leu Ser Ala Ser Pro Leu Asp Thr Ser Ala Gly Gly Glu Asp Ala 265 270 275 cca agc cca gtc gaa acc cca gag gcg gtg gag cct tcg cgg atg ctg 979 Pro Ser Pro Val Glu Thr Pro Glu Ala Val Glu Pro Ser Arg Met Leu 280 285 290 aac cca agt ggg gag gcg tcg ata agc tat aaa ccc ggg cgc gcc gac 1027 Asn Pro Ser Gly Glu Ala Ser Ile Ser Tyr Lys Pro Gly Arg Ala Asp 295 300 305 ttc ggt gac gtg ctc tagggcctag ccaggtaccc tta 1065 Phe Gly Asp Val Leu 310 <210> 410 <211> 314 <212> PRT <213> Corynebacterium glutamicum <400> 410 Met Ser Ile Val Glu His Ile Lys Glu Phe Arg Arg Arg Leu Leu Ile 1 5 10 15 Ala Leu Ala Gly Ile Leu Val Gly Thr Ile Ile Gly Phe Ile Trp Tyr 20 25 30 Asp Phe Ser Phe Trp Gln Ile Pro Thr Leu Gly Glu Leu Leu Arg Asp 35 40 45 Pro Tyr Cys Ser Leu Pro Ala Glu Ser Arg Trp Ala Met Ser Asp Ser 50 55 60 Glu Glu Cys Arg Leu Leu Ala Thr Gly Pro Phe Asp Pro Phe Met Leu 65 70 75 80 Arg Leu Lys Val Ala Ala Leu Val Gly Met Val Leu Gly Ser Pro Val 85 90 95 Trp Leu Ser Gln Leu Trp Gly Phe Ile Thr Pro Gly Leu Met Lys Asn 100 105 110 Glu Arg Arg Tyr Thr Ala Ile Phe Val Thr Ile Ala Val Val Leu Phe 115 120 125 Val Gly Gly Ala Val Leu Ala Tyr Phe Val Val Ala Tyr Gly Leu Glu 130 135 140 Phe Leu Leu Thr Ile Gly Gly Asp Thr Gln Ala Ala Ala Leu Thr Gly 145 150 155 160 Asp Lys Tyr Phe Gly Phe Leu Leu Ala Leu Leu Ala Ile Phe Gly Val 165 170 175 Ser Phe Glu Val Pro Leu Val Ile Gly Met Leu Asn Ile Val Gly Ile 180 185 190 Leu Pro Tyr Asp Ala Ile Lys Asp Lys Arg Arg Met Ile Ile Met Ile 195 200 205 Leu Phe Val Phe Ala Ala Phe Met Thr Pro Gly Gln Asp Pro Phe Thr 210 215 220 Met Leu Val Leu Ala Leu Ser Leu Thr Val Leu Val Glu Leu Ala Leu 225 230 235 240 Gln Phe Cys Arg Phe Asn Asp Lys Arg Arg Asp Lys Lys Arg Pro Glu 245 250 255 Trp Leu Asp Gly Asp Asp Leu Ser Ala Ser Pro Leu Asp Thr Ser Ala 260 265 270 Gly Gly Glu Asp Ala Pro Ser Pro Val Glu Thr Pro Glu Ala Val Glu 275 280 285 Pro Ser Arg Met Leu Asn Pro Ser Gly Glu Ala Ser Ile Ser Tyr Lys 290 295 300 Pro Gly Arg Ala Asp Phe Gly Asp Val Leu 305 310 <210> 411 <211> 1413 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1390) <223> RXA02458 <400> 411 ttgcggagcc acgactgatc ggtcaagtgc tatctcggtt gcatcaataa gcgaatcacc 60 ggtggtgaac aaaacaaatc ttccacacat aacatctatt atg gtc ttt gtg tct 115 Met Val Phe Val Ser 1 5 gat tcg tct atc tct ttg ccc att tgg gat gct ccg cgc gct cgc ggc 163 Asp Ser Ser Ile Ser Leu Pro Ile Trp Asp Ala Pro Arg Ala Arg Gly 10 15 20 ccc ata gtc tcg gac ctg gct atc cct ggt tcc aag tcg atc acc aac 211 Pro Ile Val Ser Asp Leu Ala Ile Pro Gly Ser Lys Ser Ile Thr Asn 25 30 35 cgc gcc ctc atc ttg gct gcg ctc gca tca act cca tcc acc atc att 259 Arg Ala Leu Ile Leu Ala Ala Leu Ala Ser Thr Pro Ser Thr Ile Ile 40 45 50 gat gtc ctt cgt agt cgt gat acc gat ctc atg act gat ggt cta cgc 307 Asp Val Leu Arg Ser Arg Asp Thr Asp Leu Met Thr Asp Gly Leu Arg 55 60 65 agc ctc gga atc acc att act gaa gag gca gtc gat cgc tac cgc gtt 355 Ser Leu Gly Ile Thr Ile Thr Glu Glu Ala Val Asp Arg Tyr Arg Val 70 75 80 85 gag ccc gga cag ttg tct gct ggc tcc gtt gag tgt ggt ctt gct ggt 403 Glu Pro Gly Gln Leu Ser Ala Gly Ser Val Glu Cys Gly Leu Ala Gly 90 95 100 acg gtc atg cgc ttt ttg cct cct gtt gct gct ttc gct gat ggt cct 451 Thr Val Met Arg Phe Leu Pro Pro Val Ala Ala Phe Ala Asp Gly Pro 105 110 115 gtt cat ttt gat ggc gat cct caa gct cgt gtt cgt ccg atg acc agc 499 Val His Phe Asp Gly Asp Pro Gln Ala Arg Val Arg Pro Met Thr Ser 120 125 130 att ttg gat gcg ctg cgt tcg ctt ggt gtg gag gta gac aac aac aat 547 Ile Leu Asp Ala Leu Arg Ser Leu Gly Val Glu Val Asp Asn Asn Asn 135 140 145 ctg cct ttc act gtt aat gct ggt gag gtc cct gag ggt ggc gtg gtt 595 Leu Pro Phe Thr Val Asn Ala Gly Glu Val Pro Glu Gly Gly Val Val 150 155 160 165 gag att gat gct tcc ggc tca tct cag ttt gtt tct ggt ctt ttg ctt 643 Glu Ile Asp Ala Ser Gly Ser Ser Gln Phe Val Ser Gly Leu Leu Leu 170 175 180 tca gcg cct cgt ttt aaa aat ggc gtc acc gtt aag cac gtc ggt ggt 691 Ser Ala Pro Arg Phe Lys Asn Gly Val Thr Val Lys His Val Gly Gly 185 190 195 cgt ctg ccg agc atg ccg cat att gag atg acc gtc gat atg ctt cgt 739 Arg Leu Pro Ser Met Pro His Ile Glu Met Thr Val Asp Met Leu Arg 200 205 210 tcc gca ggc att gag atc gaa gag tca gaa aat cag tgg gtt gtt cat 787 Ser Ala Gly Ile Glu Ile Glu Glu Ser Glu Asn Gln Trp Val Val His 215 220 225 cct ggt gag atc ttg ggt cgg acc tgg cgc att gag ccg gat ctt tct 835 Pro Gly Glu Ile Leu Gly Arg Thr Trp Arg Ile Glu Pro Asp Leu Ser 230 235 240 245 aat gcg act ccg ttc cta gct gcc gct gcg gtc act ggt gga acc atc 883 Asn Ala Thr Pro Phe Leu Ala Ala Ala Ala Val Thr Gly Gly Thr Ile 250 255 260 aag att aac cac tgg cca atc aaa act act cag cct ggc gat gct att 931 Lys Ile Asn His Trp Pro Ile Lys Thr Thr Gln Pro Gly Asp Ala Ile 265 270 275 cgt tcg att ctt gag cgc atg ggc tgc gaa gtt gag ctg gtt gct cag 979 Arg Ser Ile Leu Glu Arg Met Gly Cys Glu Val Glu Leu Val Ala Gln 280 285 290 ggt gaa ggt tac gat ctg tcg gtg act ggt ccg gtt gct ctc aag ggc 1027 Gly Glu Gly Tyr Asp Leu Ser Val Thr Gly Pro Val Ala Leu Lys Gly 295 300 305 att gag atc gat atg tcc gat atc ggt gag ttg acc cct acc gtg gcg 1075 Ile Glu Ile Asp Met Ser Asp Ile Gly Glu Leu Thr Pro Thr Val Ala 310 315 320 325 gcg ttg gct gcg ttg gcg tcg aca gag tct cgt ttg acc ggt att gct 1123 Ala Leu Ala Ala Leu Ala Ser Thr Glu Ser Arg Leu Thr Gly Ile Ala 330 335 340 cat ctt cgt ggc cat gag acg gat cgt ttg gct gcg ttg act gcg gag 1171 His Leu Arg Gly His Glu Thr Asp Arg Leu Ala Ala Leu Thr Ala Glu 345 350 355 atc aac aaa ctt ggt gga aag tgc act gag ctt aag gat ggt ctg ttg 1219 Ile Asn Lys Leu Gly Gly Lys Cys Thr Glu Leu Lys Asp Gly Leu Leu 360 365 370 att gag cct gcg tcg ctg cac ggt ggt gtg tgg cat tca tat gct gat 1267 Ile Glu Pro Ala Ser Leu His Gly Gly Val Trp His Ser Tyr Ala Asp 375 380 385 cac cgt atg gct act gct ggt gcg atc att ggc ctc gcg gtt gat ggc 1315 His Arg Met Ala Thr Ala Gly Ala Ile Ile Gly Leu Ala Val Asp Gly 390 395 400 405 gtt cag gtt gaa gac att aag acc act tcc aaa act ttc cct ggt ttt 1363 Val Gln Val Glu Asp Ile Lys Thr Thr Ser Lys Thr Phe Pro Gly Phe 410 415 420 gaa aat gtt tgg gag gag atg gtt ggc tagacgcagc tatgacgaat 1410 Glu Asn Val Trp Glu Glu Met Val Gly 425 430 ccg 1413 <210> 412 <211> 430 <212> PRT <213> Corynebacterium glutamicum <400> 412 Met Val Phe Val Ser Asp Ser Ser Ile Ser Leu Pro Ile Trp Asp Ala 1 5 10 15 Pro Arg Ala Arg Gly Pro Ile Val Ser Asp Leu Ala Ile Pro Gly Ser 20 25 30 Lys Ser Ile Thr Asn Arg Ala Leu Ile Leu Ala Ala Leu Ala Ser Thr 35 40 45 Pro Ser Thr Ile Ile Asp Val Leu Arg Ser Arg Asp Thr Asp Leu Met 50 55 60 Thr Asp Gly Leu Arg Ser Leu Gly Ile Thr Ile Thr Glu Glu Ala Val 65 70 75 80 Asp Arg Tyr Arg Val Glu Pro Gly Gln Leu Ser Ala Gly Ser Val Glu 85 90 95 Cys Gly Leu Ala Gly Thr Val Met Arg Phe Leu Pro Pro Val Ala Ala 100 105 110 Phe Ala Asp Gly Pro Val His Phe Asp Gly Asp Pro Gln Ala Arg Val 115 120 125 Arg Pro Met Thr Ser Ile Leu Asp Ala Leu Arg Ser Leu Gly Val Glu 130 135 140 Val Asp Asn Asn Asn Leu Pro Phe Thr Val Asn Ala Gly Glu Val Pro 145 150 155 160 Glu Gly Gly Val Val Glu Ile Asp Ala Ser Gly Ser Ser Gln Phe Val 165 170 175 Ser Gly Leu Leu Leu Ser Ala Pro Arg Phe Lys Asn Gly Val Thr Val 180 185 190 Lys His Val Gly Gly Arg Leu Pro Ser Met Pro His Ile Glu Met Thr 195 200 205 Val Asp Met Leu Arg Ser Ala Gly Ile Glu Ile Glu Glu Ser Glu Asn 210 215 220 Gln Trp Val Val His Pro Gly Glu Ile Leu Gly Arg Thr Trp Arg Ile 225 230 235 240 Glu Pro Asp Leu Ser Asn Ala Thr Pro Phe Leu Ala Ala Ala Ala Val 245 250 255 Thr Gly Gly Thr Ile Lys Ile Asn His Trp Pro Ile Lys Thr Thr Gln 260 265 270 Pro Gly Asp Ala Ile Arg Ser Ile Leu Glu Arg Met Gly Cys Glu Val 275 280 285 Glu Leu Val Ala Gln Gly Glu Gly Tyr Asp Leu Ser Val Thr Gly Pro 290 295 300 Val Ala Leu Lys Gly Ile Glu Ile Asp Met Ser Asp Ile Gly Glu Leu 305 310 315 320 Thr Pro Thr Val Ala Ala Leu Ala Ala Leu Ala Ser Thr Glu Ser Arg 325 330 335 Leu Thr Gly Ile Ala His Leu Arg Gly His Glu Thr Asp Arg Leu Ala 340 345 350 Ala Leu Thr Ala Glu Ile Asn Lys Leu Gly Gly Lys Cys Thr Glu Leu 355 360 365 Lys Asp Gly Leu Leu Ile Glu Pro Ala Ser Leu His Gly Gly Val Trp 370 375 380 His Ser Tyr Ala Asp His Arg Met Ala Thr Ala Gly Ala Ile Ile Gly 385 390 395 400 Leu Ala Val Asp Gly Val Gln Val Glu Asp Ile Lys Thr Thr Ser Lys 405 410 415 Thr Phe Pro Gly Phe Glu Asn Val Trp Glu Glu Met Val Gly 420 425 430 <210> 413 <211> 1266 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1243) <223> RXA02790 <400> 413 tggatgctcg cacccgagcc cttgaaccac aatccacaga cacccaagat ttcgacgaga 60 agggaaattt cccaggatga accaaatccg aaaccgccgg atg gag ccc gtc tac 115 Met Glu Pro Val Tyr 1 5 gta aag cgc cgc caa cgg ttt att gcc gtg acg atc gct tca ctc atc 163 Val Lys Arg Arg Gln Arg Phe Ile Ala Val Thr Ile Ala Ser Leu Ile 10 15 20 ctc att atc ggt gcc atc atc tat atc ggt gta gcc acc tca aac cgg 211 Leu Ile Ile Gly Ala Ile Ile Tyr Ile Gly Val Ala Thr Ser Asn Arg 25 30 35 acg cca cat gac tat gaa ggc tcc gga aac ggt gtg gtt cag ctg gtc 259 Thr Pro His Asp Tyr Glu Gly Ser Gly Asn Gly Val Val Gln Leu Val 40 45 50 gaa atc cct gaa ggt tcc tcc ata tca gag ctc ggc cca gag ttg gaa 307 Glu Ile Pro Glu Gly Ser Ser Ile Ser Glu Leu Gly Pro Glu Leu Glu 55 60 65 gaa cga gat atc gtg gcc acc aac tca gcg ttc caa aca gcg gcc agc 355 Glu Arg Asp Ile Val Ala Thr Asn Ser Ala Phe Gln Thr Ala Ala Ser 70 75 80 85 aac aac ccc aac gcg ggt agt gta cag cca ggt ttc tac cgt ctg cag 403 Asn Asn Pro Asn Ala Gly Ser Val Gln Pro Gly Phe Tyr Arg Leu Gln 90 95 100 gaa caa atg aac gca gca gct gca gtg tcg gct ctg ctt gat cca gac 451 Glu Gln Met Asn Ala Ala Ala Ala Val Ser Ala Leu Leu Asp Pro Asp 105 110 115 aac cag gtt gat ctc ctc gac att cac ggc ggc gcc acc ttg atg gac 499 Asn Gln Val Asp Leu Leu Asp Ile His Gly Gly Ala Thr Leu Met Asp 120 125 130 gtc act gtt gtc ggc gga aac acc cgc gcg gga atc tac tcc cag atc 547 Val Thr Val Val Gly Gly Asn Thr Arg Ala Gly Ile Tyr Ser Gln Ile 135 140 145 gca gcc gtg acc tgc acc gaa ggc tcc gcc aac tgc atc acc gct gag 595 Ala Ala Val Thr Cys Thr Glu Gly Ser Ala Asn Cys Ile Thr Ala Glu 150 155 160 165 gat ttg cag cag gtt gcc tcc acc gtg tcg cct gca gaa ttg ggt gtc 643 Asp Leu Gln Gln Val Ala Ser Thr Val Ser Pro Ala Glu Leu Gly Val 170 175 180 cca gat tgg gca atc gct gct gtg gaa gct cgc gga act gat cca aag 691 Pro Asp Trp Ala Ile Ala Ala Val Glu Ala Arg Gly Thr Asp Pro Lys 185 190 195 cgc ctc gaa ggc ctg atc atg cct ggc caa tac gtg gtg gat cca tcc 739 Arg Leu Glu Gly Leu Ile Met Pro Gly Gln Tyr Val Val Asp Pro Ser 200 205 210 aac gac gcc cag gga atc ctc acc gat ctg atc acg cga tca gca aac 787 Asn Asp Ala Gln Gly Ile Leu Thr Asp Leu Ile Thr Arg Ser Ala Asn 215 220 225 cat ttc caa gaa acc gac atc acg ggc cgt gca gat gcc atc gga ctt 835 His Phe Gln Glu Thr Asp Ile Thr Gly Arg Ala Asp Ala Ile Gly Leu 230 235 240 245 act cca tat gag ctg gtc acc gca gca tct tta atc gag cgc gaa gca 883 Thr Pro Tyr Glu Leu Val Thr Ala Ala Ser Leu Ile Glu Arg Glu Ala 250 255 260 cca gca gga gat ttt gat aag gtc gcc cgc gtc atc ttg aac cgt ctc 931 Pro Ala Gly Asp Phe Asp Lys Val Ala Arg Val Ile Leu Asn Arg Leu 265 270 275 gcc gag cca atg cag ctg caa ttc gac tcc acc gtc aac tac ggt ctg 979 Ala Glu Pro Met Gln Leu Gln Phe Asp Ser Thr Val Asn Tyr Gly Leu 280 285 290 tct gaa caa gaa gta gca acc acc gac gaa gac cgt cag acc gtc acc 1027 Ser Glu Gln Glu Val Ala Thr Thr Asp Glu Asp Arg Gln Thr Val Thr 295 300 305 cca tgg aac act tac gcc atg gac ggc ctg cca caa acc ccc atc gcc 1075 Pro Trp Asn Thr Tyr Ala Met Asp Gly Leu Pro Gln Thr Pro Ile Ala 310 315 320 325 gca gta tcc acc gaa gca ctc caa gcc atg gaa aac cct gca gaa gga 1123 Ala Val Ser Thr Glu Ala Leu Gln Ala Met Glu Asn Pro Ala Glu Gly 330 335 340 aac tgg ctg tac ttt gtc acc atc gac acc gat gga acc acc gtg ttc 1171 Asn Trp Leu Tyr Phe Val Thr Ile Asp Thr Asp Gly Thr Thr Val Phe 345 350 355 aac gac acc ttc gaa gag cac gaa gcc gac att gag caa gct ttg aac 1219 Asn Asp Thr Phe Glu Glu His Glu Ala Asp Ile Glu Gln Ala Leu Asn 360 365 370 agt ggc gtt cta gac agc aac cga taaggatcag cgaataaaat tgg 1266 Ser Gly Val Leu Asp Ser Asn Arg 375 380 <210> 414 <211> 381 <212> PRT <213> Corynebacterium glutamicum <400> 414 Met Glu Pro Val Tyr Val Lys Arg Arg Gln Arg Phe Ile Ala Val Thr 1 5 10 15 Ile Ala Ser Leu Ile Leu Ile Ile Gly Ala Ile Ile Tyr Ile Gly Val 20 25 30 Ala Thr Ser Asn Arg Thr Pro His Asp Tyr Glu Gly Ser Gly Asn Gly 35 40 45 Val Val Gln Leu Val Glu Ile Pro Glu Gly Ser Ser Ile Ser Glu Leu 50 55 60 Gly Pro Glu Leu Glu Glu Arg Asp Ile Val Ala Thr Asn Ser Ala Phe 65 70 75 80 Gln Thr Ala Ala Ser Asn Asn Pro Asn Ala Gly Ser Val Gln Pro Gly 85 90 95 Phe Tyr Arg Leu Gln Glu Gln Met Asn Ala Ala Ala Ala Val Ser Ala 100 105 110 Leu Leu Asp Pro Asp Asn Gln Val Asp Leu Leu Asp Ile His Gly Gly 115 120 125 Ala Thr Leu Met Asp Val Thr Val Val Gly Gly Asn Thr Arg Ala Gly 130 135 140 Ile Tyr Ser Gln Ile Ala Ala Val Thr Cys Thr Glu Gly Ser Ala Asn 145 150 155 160 Cys Ile Thr Ala Glu Asp Leu Gln Gln Val Ala Ser Thr Val Ser Pro 165 170 175 Ala Glu Leu Gly Val Pro Asp Trp Ala Ile Ala Ala Val Glu Ala Arg 180 185 190 Gly Thr Asp Pro Lys Arg Leu Glu Gly Leu Ile Met Pro Gly Gln Tyr 195 200 205 Val Val Asp Pro Ser Asn Asp Ala Gln Gly Ile Leu Thr Asp Leu Ile 210 215 220 Thr Arg Ser Ala Asn His Phe Gln Glu Thr Asp Ile Thr Gly Arg Ala 225 230 235 240 Asp Ala Ile Gly Leu Thr Pro Tyr Glu Leu Val Thr Ala Ala Ser Leu 245 250 255 Ile Glu Arg Glu Ala Pro Ala Gly Asp Phe Asp Lys Val Ala Arg Val 260 265 270 Ile Leu Asn Arg Leu Ala Glu Pro Met Gln Leu Gln Phe Asp Ser Thr 275 280 285 Val Asn Tyr Gly Leu Ser Glu Gln Glu Val Ala Thr Thr Asp Glu Asp 290 295 300 Arg Gln Thr Val Thr Pro Trp Asn Thr Tyr Ala Met Asp Gly Leu Pro 305 310 315 320 Gln Thr Pro Ile Ala Ala Val Ser Thr Glu Ala Leu Gln Ala Met Glu 325 330 335 Asn Pro Ala Glu Gly Asn Trp Leu Tyr Phe Val Thr Ile Asp Thr Asp 340 345 350 Gly Thr Thr Val Phe Asn Asp Thr Phe Glu Glu His Glu Ala Asp Ile 355 360 365 Glu Gln Ala Leu Asn Ser Gly Val Leu Asp Ser Asn Arg 370 375 380 <210> 415 <211> 644 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(621) <223> RXN00954 <400> 415 gct gtg aag tgg ttc gaa gcg tcc aac ttc acc ttc ctg ttc gca cct 48 Ala Val Lys Trp Phe Glu Ala Ser Asn Phe Thr Phe Leu Phe Ala Pro 1 5 10 15 gcg tac aac cct gcg att gcg cat gtg cag ccg gtt cgc cag gcg ctg 96 Ala Tyr Asn Pro Ala Ile Ala His Val Gln Pro Val Arg Gln Ala Leu 20 25 30 aaa ttc ccc acc atc ttc aac acg ctt gga cca ttg ctg tcc ccg gcg 144 Lys Phe Pro Thr Ile Phe Asn Thr Leu Gly Pro Leu Leu Ser Pro Ala 35 40 45 cgc ccg gag cgt cag atc atg ggc gtg gcc aat gcc aat cat gga cag 192 Arg Pro Glu Arg Gln Ile Met Gly Val Ala Asn Ala Asn His Gly Gln 50 55 60 ctc atc gcc gag gtc ttc cgc gag ttg ggc cgt aca cgc gcg ctt gtt 240 Leu Ile Ala Glu Val Phe Arg Glu Leu Gly Arg Thr Arg Ala Leu Val 65 70 75 80 gtg cat ggc gca ggc acc gat gag atc gca gtc cac ggc acc acc ttg 288 Val His Gly Ala Gly Thr Asp Glu Ile Ala Val His Gly Thr Thr Leu 85 90 95 gtg tgg gag ctt aaa gaa gac ggc acc atc gag cat tac acc atc gag 336 Val Trp Glu Leu Lys Glu Asp Gly Thr Ile Glu His Tyr Thr Ile Glu 100 105 110 cct gag gac ctt ggc ctt ggc cgc tac acc ctt gag gat ctc gta ggt 384 Pro Glu Asp Leu Gly Leu Gly Arg Tyr Thr Leu Glu Asp Leu Val Gly 115 120 125 ggc ctc ggc act gag aac gcc gaa gct atg cgc gct act ttc gcg ggc 432 Gly Leu Gly Thr Glu Asn Ala Glu Ala Met Arg Ala Thr Phe Ala Gly 130 135 140 acc ggc cct gat gca cac cgt gat gcg ttg gct gcg tcc gca ggt gcg 480 Thr Gly Pro Asp Ala His Arg Asp Ala Leu Ala Ala Ser Ala Gly Ala 145 150 155 160 atg ttc tac ctc aac ggc gat gtc gac tcc ttg aaa gat ggt gca caa 528 Met Phe Tyr Leu Asn Gly Asp Val Asp Ser Leu Lys Asp Gly Ala Gln 165 170 175 aag gcg ctt tcc ttg ctt gcc gac ggc acc acc cag gca tgg ttg gcc 576 Lys Ala Leu Ser Leu Leu Ala Asp Gly Thr Thr Gln Ala Trp Leu Ala 180 185 190 aag cac gaa gag atc gat tac tca gaa aag gag tct tcc aat gac 621 Lys His Glu Glu Ile Asp Tyr Ser Glu Lys Glu Ser Ser Asn Asp 195 200 205 tagtaataat ctgcccacag tgt 644 <210> 416 <211> 207 <212> PRT <213> Corynebacterium glutamicum <400> 416 Ala Val Lys Trp Phe Glu Ala Ser Asn Phe Thr Phe Leu Phe Ala Pro 1 5 10 15 Ala Tyr Asn Pro Ala Ile Ala His Val Gln Pro Val Arg Gln Ala Leu 20 25 30 Lys Phe Pro Thr Ile Phe Asn Thr Leu Gly Pro Leu Leu Ser Pro Ala 35 40 45 Arg Pro Glu Arg Gln Ile Met Gly Val Ala Asn Ala Asn His Gly Gln 50 55 60 Leu Ile Ala Glu Val Phe Arg Glu Leu Gly Arg Thr Arg Ala Leu Val 65 70 75 80 Val His Gly Ala Gly Thr Asp Glu Ile Ala Val His Gly Thr Thr Leu 85 90 95 Val Trp Glu Leu Lys Glu Asp Gly Thr Ile Glu His Tyr Thr Ile Glu 100 105 110 Pro Glu Asp Leu Gly Leu Gly Arg Tyr Thr Leu Glu Asp Leu Val Gly 115 120 125 Gly Leu Gly Thr Glu Asn Ala Glu Ala Met Arg Ala Thr Phe Ala Gly 130 135 140 Thr Gly Pro Asp Ala His Arg Asp Ala Leu Ala Ala Ser Ala Gly Ala 145 150 155 160 Met Phe Tyr Leu Asn Gly Asp Val Asp Ser Leu Lys Asp Gly Ala Gln 165 170 175 Lys Ala Leu Ser Leu Leu Ala Asp Gly Thr Thr Gln Ala Trp Leu Ala 180 185 190 Lys His Glu Glu Ile Asp Tyr Ser Glu Lys Glu Ser Ser Asn Asp 195 200 205 <210> 417 <211> 611 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(588) <223> FRXA00954 <400> 417 ttc ctg ttc gca cct gcg tac aac cct gcg att gcg cat gtg cag ccg 48 Phe Leu Phe Ala Pro Ala Tyr Asn Pro Ala Ile Ala His Val Gln Pro 1 5 10 15 gtt cgc cag gcg ctg aaa ttc ccc acc atc ttc aac acg ctt gga cca 96 Val Arg Gln Ala Leu Lys Phe Pro Thr Ile Phe Asn Thr Leu Gly Pro 20 25 30 ttg ctg tcc ccg gcg cgc ccg gag cgt cag atc atg ggc gtg gcc aat 144 Leu Leu Ser Pro Ala Arg Pro Glu Arg Gln Ile Met Gly Val Ala Asn 35 40 45 gcc aat cat gga cag ctc atc gcc gag gtc ttc cgc gag ttg ggc cgt 192 Ala Asn His Gly Gln Leu Ile Ala Glu Val Phe Arg Glu Leu Gly Arg 50 55 60 aca cgc gcg ctt gtt gtg cat ggc gca ggc acc gat gag atc gca gtc 240 Thr Arg Ala Leu Val Val His Gly Ala Gly Thr Asp Glu Ile Ala Val 65 70 75 80 cac ggc acc acc ttg gtg tgg gag ctt aaa gaa gac ggc acc atc gag 288 His Gly Thr Thr Leu Val Trp Glu Leu Lys Glu Asp Gly Thr Ile Glu 85 90 95 cat tac acc atc gag cct gag gac ctt ggc ctt ggc cgc tac acc ctt 336 His Tyr Thr Ile Glu Pro Glu Asp Leu Gly Leu Gly Arg Tyr Thr Leu 100 105 110 gag gat ctc gta ggt ggc ctc ggc act gag aac gcc gaa gct atg cgc 384 Glu Asp Leu Val Gly Gly Leu Gly Thr Glu Asn Ala Glu Ala Met Arg 115 120 125 gct act ttc gcg ggc acc ggc cct gat gca cac cgt gat gcg ttg gct 432 Ala Thr Phe Ala Gly Thr Gly Pro Asp Ala His Arg Asp Ala Leu Ala 130 135 140 gcg tcc gca ggt gcg atg ttc tac ctc aac ggc gat gtc gac tcc ttg 480 Ala Ser Ala Gly Ala Met Phe Tyr Leu Asn Gly Asp Val Asp Ser Leu 145 150 155 160 aaa gat ggt gca caa aag gcg ctt tcc ttg ctt gcc gac ggc acc acc 528 Lys Asp Gly Ala Gln Lys Ala Leu Ser Leu Leu Ala Asp Gly Thr Thr 165 170 175 cag gca tgg ttg gcc aag cac gaa gag atc gat tac tca gaa aag gag 576 Gln Ala Trp Leu Ala Lys His Glu Glu Ile Asp Tyr Ser Glu Lys Glu 180 185 190 tct tcc aat gac tagtaataat ctgcccacag tgt 611 Ser Ser Asn Asp 195 <210> 418 <211> 196 <212> PRT <213> Corynebacterium glutamicum <400> 418 Phe Leu Phe Ala Pro Ala Tyr Asn Pro Ala Ile Ala His Val Gln Pro 1 5 10 15 Val Arg Gln Ala Leu Lys Phe Pro Thr Ile Phe Asn Thr Leu Gly Pro 20 25 30 Leu Leu Ser Pro Ala Arg Pro Glu Arg Gln Ile Met Gly Val Ala Asn 35 40 45 Ala Asn His Gly Gln Leu Ile Ala Glu Val Phe Arg Glu Leu Gly Arg 50 55 60 Thr Arg Ala Leu Val Val His Gly Ala Gly Thr Asp Glu Ile Ala Val 65 70 75 80 His Gly Thr Thr Leu Val Trp Glu Leu Lys Glu Asp Gly Thr Ile Glu 85 90 95 His Tyr Thr Ile Glu Pro Glu Asp Leu Gly Leu Gly Arg Tyr Thr Leu 100 105 110 Glu Asp Leu Val Gly Gly Leu Gly Thr Glu Asn Ala Glu Ala Met Arg 115 120 125 Ala Thr Phe Ala Gly Thr Gly Pro Asp Ala His Arg Asp Ala Leu Ala 130 135 140 Ala Ser Ala Gly Ala Met Phe Tyr Leu Asn Gly Asp Val Asp Ser Leu 145 150 155 160 Lys Asp Gly Ala Gln Lys Ala Leu Ser Leu Leu Ala Asp Gly Thr Thr 165 170 175 Gln Ala Trp Leu Ala Lys His Glu Glu Ile Asp Tyr Ser Glu Lys Glu 180 185 190 Ser Ser Asn Asp 195 <210> 419 <211> 1677 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1654) <223> RXN00957 <400> 419 aaccggcaag ccctggatcg aatgaagctc gcagcgagta attatttgat gtttcccaga 60 aaggcttcag ccccacaatg atttcctcgg taggtgcccc atg agc acg aat ccc 115 Met Ser Thr Asn Pro 1 5 cat gtt ttc tcc cta gat gtc cgc tat cac gag gat gct tct gca ttg 163 His Val Phe Ser Leu Asp Val Arg Tyr His Glu Asp Ala Ser Ala Leu 10 15 20 ttt gcc cac ttg ggt ggc aca acc gca gat gat gca gcc ctg ttg gaa 211 Phe Ala His Leu Gly Gly Thr Thr Ala Asp Asp Ala Ala Leu Leu Glu 25 30 35 agc gct gat atc acc acc aag aat ggt att tct tcc ctc gcg gtg ttg 259 Ser Ala Asp Ile Thr Thr Lys Asn Gly Ile Ser Ser Leu Ala Val Leu 40 45 50 aag agt tcg gtg cgc att acg tgc acg ggc aac acg gtg gta acg cag 307 Lys Ser Ser Val Arg Ile Thr Cys Thr Gly Asn Thr Val Val Thr Gln 55 60 65 ccg ctg acg gac tcg ggt agg gca gtg gtt gcg cgc cta acg cag cag 355 Pro Leu Thr Asp Ser Gly Arg Ala Val Val Ala Arg Leu Thr Gln Gln 70 75 80 85 ctt ggc cag tac aac acc gca gag aac acc ttt agc ttc ccc gcc tca 403 Leu Gly Gln Tyr Asn Thr Ala Glu Asn Thr Phe Ser Phe Pro Ala Ser 90 95 100 gat gcg gtt gat gag cgc gag cgc ctc acc gca cca agc acc atc gaa 451 Asp Ala Val Asp Glu Arg Glu Arg Leu Thr Ala Pro Ser Thr Ile Glu 105 110 115 gtg ctg cgc aag ttg cag ttc gag tcc ggt tac agc gac gcg tcc ctg 499 Val Leu Arg Lys Leu Gln Phe Glu Ser Gly Tyr Ser Asp Ala Ser Leu 120 125 130 cca ctg ctc atg ggc ggt ttc gcg ttt gat ttc tta gaa acc ttt gaa 547 Pro Leu Leu Met Gly Gly Phe Ala Phe Asp Phe Leu Glu Thr Phe Glu 135 140 145 acg ctc ccc gct gtc gag gag agc gtc aac act tac ccc gat tac cag 595 Thr Leu Pro Ala Val Glu Glu Ser Val Asn Thr Tyr Pro Asp Tyr Gln 150 155 160 165 ttc gtc ctc gcg gaa atc gtc ctg gac atc aat cac cag gac cag acc 643 Phe Val Leu Ala Glu Ile Val Leu Asp Ile Asn His Gln Asp Gln Thr 170 175 180 gcc aaa ctc gcc ggc gtc tcc aac gcc cca ggc gag ctc gag gcc gag 691 Ala Lys Leu Ala Gly Val Ser Asn Ala Pro Gly Glu Leu Glu Ala Glu 185 190 195 ctc aac aag ctt tca ttg ctt atc gac gcc gcc ctc ccc gca acc gaa 739 Leu Asn Lys Leu Ser Leu Leu Ile Asp Ala Ala Leu Pro Ala Thr Glu 200 205 210 cac gcc tac caa acc acc cct cac gac ggc gac act ctt cgc gtt gtg 787 His Ala Tyr Gln Thr Thr Pro His Asp Gly Asp Thr Leu Arg Val Val 215 220 225 gct gat att ccc gat gct cag ttc cgc acc cag atc aat gag ctg aaa 835 Ala Asp Ile Pro Asp Ala Gln Phe Arg Thr Gln Ile Asn Glu Leu Lys 230 235 240 245 gaa aac att tac aac ggt gac atc tac caa gtt gtc ccg gcg cgc act 883 Glu Asn Ile Tyr Asn Gly Asp Ile Tyr Gln Val Val Pro Ala Arg Thr 250 255 260 ttc acc gca cca tgt cct gat gca ttc gct gct tat ctg cag ctg cgt 931 Phe Thr Ala Pro Cys Pro Asp Ala Phe Ala Ala Tyr Leu Gln Leu Arg 265 270 275 gcc acc aac ccg tcg ccg tac atg ttc tat atc cgt ggc ctc aac gaa 979 Ala Thr Asn Pro Ser Pro Tyr Met Phe Tyr Ile Arg Gly Leu Asn Glu 280 285 290 ggc cgc tcc tat gaa ctt ttt ggc gca tcc cct gag tcc aac ctc aag 1027 Gly Arg Ser Tyr Glu Leu Phe Gly Ala Ser Pro Glu Ser Asn Leu Lys 295 300 305 ttc acc gct gct aac cgt gag ctg cag ctg tac cca atc gca ggt acc 1075 Phe Thr Ala Ala Asn Arg Glu Leu Gln Leu Tyr Pro Ile Ala Gly Thr 310 315 320 325 cgc ccc cgt gga ctc aac cca gat ggc tcc atc aac gat gag cta gat 1123 Arg Pro Arg Gly Leu Asn Pro Asp Gly Ser Ile Asn Asp Glu Leu Asp 330 335 340 atc cgc aat gag ttg gat atg cgc act gat gcc aaa gag atc gcg gag 1171 Ile Arg Asn Glu Leu Asp Met Arg Thr Asp Ala Lys Glu Ile Ala Glu 345 350 355 cac acc atg ctt gtc gat ctc gcc cgc aac gac ctg gcc cgc gtc tcg 1219 His Thr Met Leu Val Asp Leu Ala Arg Asn Asp Leu Ala Arg Val Ser 360 365 370 gtc cca gcg tcg cgc cgg gtt gcg gat ctt ttg cag gtg gat cgc tat 1267 Val Pro Ala Ser Arg Arg Val Ala Asp Leu Leu Gln Val Asp Arg Tyr 375 380 385 tcc cgc gtg atg cac ttg gtg tcc cgt gtg acg gcg acg ttg gac cca 1315 Ser Arg Val Met His Leu Val Ser Arg Val Thr Ala Thr Leu Asp Pro 390 395 400 405 gag ctt gat gct ttg gac gcc tat cgg gcg tgc atg aat atg ggc acg 1363 Glu Leu Asp Ala Leu Asp Ala Tyr Arg Ala Cys Met Asn Met Gly Thr 410 415 420 ttg acc ggc gct ccg aag ttg cgc gct atg gag ctg ttg cgc ggc gtc 1411 Leu Thr Gly Ala Pro Lys Leu Arg Ala Met Glu Leu Leu Arg Gly Val 425 430 435 gaa aag cgc agg cgt ggt tct tat ggt ggg gca gtg ggg tac ctg cgc 1459 Glu Lys Arg Arg Arg Gly Ser Tyr Gly Gly Ala Val Gly Tyr Leu Arg 440 445 450 ggc aat ggc gat atg gat aat tgc att gtt att cgt tcg gcg ttt gtc 1507 Gly Asn Gly Asp Met Asp Asn Cys Ile Val Ile Arg Ser Ala Phe Val 455 460 465 cag gat ggt gtg gct gct gtg cag gct ggt gct ggt gtg gtc cgc gat 1555 Gln Asp Gly Val Ala Ala Val Gln Ala Gly Ala Gly Val Val Arg Asp 470 475 480 485 tct aat cct caa tct gaa gcc gat gag acg ttg cac aag gcg tat gcc 1603 Ser Asn Pro Gln Ser Glu Ala Asp Glu Thr Leu His Lys Ala Tyr Ala 490 495 500 gtg ttg aat gcc att gcg ctt gct gct ggt tcc act ttg gag gtc atc 1651 Val Leu Asn Ala Ile Ala Leu Ala Ala Gly Ser Thr Leu Glu Val Ile 505 510 515 cga tgacacacgt tgttctcatt gat 1677 Arg <210> 420 <211> 518 <212> PRT <213> Corynebacterium glutamicum <400> 420 Met Ser Thr Asn Pro His Val Phe Ser Leu Asp Val Arg Tyr His Glu 1 5 10 15 Asp Ala Ser Ala Leu Phe Ala His Leu Gly Gly Thr Thr Ala Asp Asp 20 25 30 Ala Ala Leu Leu Glu Ser Ala Asp Ile Thr Thr Lys Asn Gly Ile Ser 35 40 45 Ser Leu Ala Val Leu Lys Ser Ser Val Arg Ile Thr Cys Thr Gly Asn 50 55 60 Thr Val Val Thr Gln Pro Leu Thr Asp Ser Gly Arg Ala Val Val Ala 65 70 75 80 Arg Leu Thr Gln Gln Leu Gly Gln Tyr Asn Thr Ala Glu Asn Thr Phe 85 90 95 Ser Phe Pro Ala Ser Asp Ala Val Asp Glu Arg Glu Arg Leu Thr Ala 100 105 110 Pro Ser Thr Ile Glu Val Leu Arg Lys Leu Gln Phe Glu Ser Gly Tyr 115 120 125 Ser Asp Ala Ser Leu Pro Leu Leu Met Gly Gly Phe Ala Phe Asp Phe 130 135 140 Leu Glu Thr Phe Glu Thr Leu Pro Ala Val Glu Glu Ser Val Asn Thr 145 150 155 160 Tyr Pro Asp Tyr Gln Phe Val Leu Ala Glu Ile Val Leu Asp Ile Asn 165 170 175 His Gln Asp Gln Thr Ala Lys Leu Ala Gly Val Ser Asn Ala Pro Gly 180 185 190 Glu Leu Glu Ala Glu Leu Asn Lys Leu Ser Leu Leu Ile Asp Ala Ala 195 200 205 Leu Pro Ala Thr Glu His Ala Tyr Gln Thr Thr Pro His Asp Gly Asp 210 215 220 Thr Leu Arg Val Val Ala Asp Ile Pro Asp Ala Gln Phe Arg Thr Gln 225 230 235 240 Ile Asn Glu Leu Lys Glu Asn Ile Tyr Asn Gly Asp Ile Tyr Gln Val 245 250 255 Val Pro Ala Arg Thr Phe Thr Ala Pro Cys Pro Asp Ala Phe Ala Ala 260 265 270 Tyr Leu Gln Leu Arg Ala Thr Asn Pro Ser Pro Tyr Met Phe Tyr Ile 275 280 285 Arg Gly Leu Asn Glu Gly Arg Ser Tyr Glu Leu Phe Gly Ala Ser Pro 290 295 300 Glu Ser Asn Leu Lys Phe Thr Ala Ala Asn Arg Glu Leu Gln Leu Tyr 305 310 315 320 Pro Ile Ala Gly Thr Arg Pro Arg Gly Leu Asn Pro Asp Gly Ser Ile 325 330 335 Asn Asp Glu Leu Asp Ile Arg Asn Glu Leu Asp Met Arg Thr Asp Ala 340 345 350 Lys Glu Ile Ala Glu His Thr Met Leu Val Asp Leu Ala Arg Asn Asp 355 360 365 Leu Ala Arg Val Ser Val Pro Ala Ser Arg Arg Val Ala Asp Leu Leu 370 375 380 Gln Val Asp Arg Tyr Ser Arg Val Met His Leu Val Ser Arg Val Thr 385 390 395 400 Ala Thr Leu Asp Pro Glu Leu Asp Ala Leu Asp Ala Tyr Arg Ala Cys 405 410 415 Met Asn Met Gly Thr Leu Thr Gly Ala Pro Lys Leu Arg Ala Met Glu 420 425 430 Leu Leu Arg Gly Val Glu Lys Arg Arg Arg Gly Ser Tyr Gly Gly Ala 435 440 445 Val Gly Tyr Leu Arg Gly Asn Gly Asp Met Asp Asn Cys Ile Val Ile 450 455 460 Arg Ser Ala Phe Val Gln Asp Gly Val Ala Ala Val Gln Ala Gly Ala 465 470 475 480 Gly Val Val Arg Asp Ser Asn Pro Gln Ser Glu Ala Asp Glu Thr Leu 485 490 495 His Lys Ala Tyr Ala Val Leu Asn Ala Ile Ala Leu Ala Ala Gly Ser 500 505 510 Thr Leu Glu Val Ile Arg 515 <210> 421 <211> 1151 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1128) <223> FRXA00957 <400> 421 gat ttc tta gaa acc ttt gaa acg ctc ccc gct gtc gag gag agc gtc 48 Asp Phe Leu Glu Thr Phe Glu Thr Leu Pro Ala Val Glu Glu Ser Val 1 5 10 15 aac act tac ccc gat tac cag ttc gtc ctc gcg gaa atc gtc ctg gac 96 Asn Thr Tyr Pro Asp Tyr Gln Phe Val Leu Ala Glu Ile Val Leu Asp 20 25 30 atc aat cac cag gac cag acc gcc aaa ctc gcc ggc gtc tcc aac gcc 144 Ile Asn His Gln Asp Gln Thr Ala Lys Leu Ala Gly Val Ser Asn Ala 35 40 45 cca ggc gag ctc gag gcc gag ctc aac aag ctt tca ttg ctt atc gac 192 Pro Gly Glu Leu Glu Ala Glu Leu Asn Lys Leu Ser Leu Leu Ile Asp 50 55 60 gcc gcc ctc ccc gca acc gaa cac gcc tac caa acc acc cct cac gac 240 Ala Ala Leu Pro Ala Thr Glu His Ala Tyr Gln Thr Thr Pro His Asp 65 70 75 80 ggc gac act ctt cgc gtt gtg gct gat att ccc gat gct cag ttc cgc 288 Gly Asp Thr Leu Arg Val Val Ala Asp Ile Pro Asp Ala Gln Phe Arg 85 90 95 acc cag atc aat gag ctg aaa gaa aac att tac aac ggt gac atc tac 336 Thr Gln Ile Asn Glu Leu Lys Glu Asn Ile Tyr Asn Gly Asp Ile Tyr 100 105 110 caa gtt gtc ccg gcg cgc act ttc acc gca cca tgt cct gat gca ttc 384 Gln Val Val Pro Ala Arg Thr Phe Thr Ala Pro Cys Pro Asp Ala Phe 115 120 125 gct gct tat ctg cag ctg cgt gcc acc aac ccg tcg ccg tac atg ttc 432 Ala Ala Tyr Leu Gln Leu Arg Ala Thr Asn Pro Ser Pro Tyr Met Phe 130 135 140 tat atc cgt ggc ctc aac gaa ggc cgc tcc tat gaa ctt ttt ggc gca 480 Tyr Ile Arg Gly Leu Asn Glu Gly Arg Ser Tyr Glu Leu Phe Gly Ala 145 150 155 160 tcc cct gag tcc aac ctc aag ttc acc gct gct aac cgt gag ctg cag 528 Ser Pro Glu Ser Asn Leu Lys Phe Thr Ala Ala Asn Arg Glu Leu Gln 165 170 175 ctg tac cca atc gca ggt acc cgc ccc cgt gga ctc aac cca gat ggc 576 Leu Tyr Pro Ile Ala Gly Thr Arg Pro Arg Gly Leu Asn Pro Asp Gly 180 185 190 tcc atc aac gat gag cta gat atc cgc aat gag ttg gat atg cgc act 624 Ser Ile Asn Asp Glu Leu Asp Ile Arg Asn Glu Leu Asp Met Arg Thr 195 200 205 gat gcc aaa gag atc gcg gag cac acc atg ctt gtc gat ctc gcc cgc 672 Asp Ala Lys Glu Ile Ala Glu His Thr Met Leu Val Asp Leu Ala Arg 210 215 220 aac gac ctg gcc cgc gtc tcg gtc cca gcg tcg cgc cgg gtt gcg gat 720 Asn Asp Leu Ala Arg Val Ser Val Pro Ala Ser Arg Arg Val Ala Asp 225 230 235 240 ctt ttg cag gtg gat cgc tat tcc cgc gtg atg cac ttg gtg tcc cgt 768 Leu Leu Gln Val Asp Arg Tyr Ser Arg Val Met His Leu Val Ser Arg 245 250 255 gtg acg gcg acg ttg gac cca gag ctt gat gct ttg gac gcc tat cgg 816 Val Thr Ala Thr Leu Asp Pro Glu Leu Asp Ala Leu Asp Ala Tyr Arg 260 265 270 gcg tgc atg aat atg ggc acg ttg acc ggc gct ccg aag ttg cgc gct 864 Ala Cys Met Asn Met Gly Thr Leu Thr Gly Ala Pro Lys Leu Arg Ala 275 280 285 atg gag ctg ttg cgc ggc gtc gaa aag cgc agg cgt ggt tct tat ggt 912 Met Glu Leu Leu Arg Gly Val Glu Lys Arg Arg Arg Gly Ser Tyr Gly 290 295 300 ggg gca gtg ggg tac ctg cgc ggc aat ggc gat atg gat aat tgc att 960 Gly Ala Val Gly Tyr Leu Arg Gly Asn Gly Asp Met Asp Asn Cys Ile 305 310 315 320 gtt att cgt tcg gcg ttt gtc cag gat ggt gtg gct gct gtg cag gct 1008 Val Ile Arg Ser Ala Phe Val Gln Asp Gly Val Ala Ala Val Gln Ala 325 330 335 ggt gct ggt gtg gtc cgc gat tct aat cct caa tct gaa gcc gat gag 1056 Gly Ala Gly Val Val Arg Asp Ser Asn Pro Gln Ser Glu Ala Asp Glu 340 345 350 acg ttg cac aag gcg tat gcc gtg ttg aat gcc att gcg ctt gct gct 1104 Thr Leu His Lys Ala Tyr Ala Val Leu Asn Ala Ile Ala Leu Ala Ala 355 360 365 ggt tcc act ttg gag gtc atc cga tgacacacgt tgttctcatt gat 1151 Gly Ser Thr Leu Glu Val Ile Arg 370 375 <210> 422 <211> 376 <212> PRT <213> Corynebacterium glutamicum <400> 422 Asp Phe Leu Glu Thr Phe Glu Thr Leu Pro Ala Val Glu Glu Ser Val 1 5 10 15 Asn Thr Tyr Pro Asp Tyr Gln Phe Val Leu Ala Glu Ile Val Leu Asp 20 25 30 Ile Asn His Gln Asp Gln Thr Ala Lys Leu Ala Gly Val Ser Asn Ala 35 40 45 Pro Gly Glu Leu Glu Ala Glu Leu Asn Lys Leu Ser Leu Leu Ile Asp 50 55 60 Ala Ala Leu Pro Ala Thr Glu His Ala Tyr Gln Thr Thr Pro His Asp 65 70 75 80 Gly Asp Thr Leu Arg Val Val Ala Asp Ile Pro Asp Ala Gln Phe Arg 85 90 95 Thr Gln Ile Asn Glu Leu Lys Glu Asn Ile Tyr Asn Gly Asp Ile Tyr 100 105 110 Gln Val Val Pro Ala Arg Thr Phe Thr Ala Pro Cys Pro Asp Ala Phe 115 120 125 Ala Ala Tyr Leu Gln Leu Arg Ala Thr Asn Pro Ser Pro Tyr Met Phe 130 135 140 Tyr Ile Arg Gly Leu Asn Glu Gly Arg Ser Tyr Glu Leu Phe Gly Ala 145 150 155 160 Ser Pro Glu Ser Asn Leu Lys Phe Thr Ala Ala Asn Arg Glu Leu Gln 165 170 175 Leu Tyr Pro Ile Ala Gly Thr Arg Pro Arg Gly Leu Asn Pro Asp Gly 180 185 190 Ser Ile Asn Asp Glu Leu Asp Ile Arg Asn Glu Leu Asp Met Arg Thr 195 200 205 Asp Ala Lys Glu Ile Ala Glu His Thr Met Leu Val Asp Leu Ala Arg 210 215 220 Asn Asp Leu Ala Arg Val Ser Val Pro Ala Ser Arg Arg Val Ala Asp 225 230 235 240 Leu Leu Gln Val Asp Arg Tyr Ser Arg Val Met His Leu Val Ser Arg 245 250 255 Val Thr Ala Thr Leu Asp Pro Glu Leu Asp Ala Leu Asp Ala Tyr Arg 260 265 270 Ala Cys Met Asn Met Gly Thr Leu Thr Gly Ala Pro Lys Leu Arg Ala 275 280 285 Met Glu Leu Leu Arg Gly Val Glu Lys Arg Arg Arg Gly Ser Tyr Gly 290 295 300 Gly Ala Val Gly Tyr Leu Arg Gly Asn Gly Asp Met Asp Asn Cys Ile 305 310 315 320 Val Ile Arg Ser Ala Phe Val Gln Asp Gly Val Ala Ala Val Gln Ala 325 330 335 Gly Ala Gly Val Val Arg Asp Ser Asn Pro Gln Ser Glu Ala Asp Glu 340 345 350 Thr Leu His Lys Ala Tyr Ala Val Leu Asn Ala Ile Ala Leu Ala Ala 355 360 365 Gly Ser Thr Leu Glu Val Ile Arg 370 375 <210> 423 <211> 1068 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1045) <223> RXA02687 <400> 423 caaaaccatg ctcggcgggg gagagttggg ccaagcggtt cgctaattga gcaacagaca 60 tggacaccca ccttagttcg gcgggttaag ctgtgtaacc atg agc gac gca cca 115 Met Ser Asp Ala Pro 1 5 act gtt gtg gcc tat ttg ggg cct gcc gga acc ttc acc gaa gaa gcc 163 Thr Val Val Ala Tyr Leu Gly Pro Ala Gly Thr Phe Thr Glu Glu Ala 10 15 20 ctc tac aaa ttt gcc gac gcc ggc gta ttc ggc gac ggt gag atc gag 211 Leu Tyr Lys Phe Ala Asp Ala Gly Val Phe Gly Asp Gly Glu Ile Glu 25 30 35 cag cta cca gcc aaa tcg cca caa gaa gct gtc gac gcc gtc cgc cac 259 Gln Leu Pro Ala Lys Ser Pro Gln Glu Ala Val Asp Ala Val Arg His 40 45 50 ggc acc gcc cag ttc gcg gtg gtc gcc atc gaa aac ttc gtc gac ggc 307 Gly Thr Ala Gln Phe Ala Val Val Ala Ile Glu Asn Phe Val Asp Gly 55 60 65 ccc gtc acc ccc acc ttc gac gcc ctt gac cag ggc tcc aac gtg caa 355 Pro Val Thr Pro Thr Phe Asp Ala Leu Asp Gln Gly Ser Asn Val Gln 70 75 80 85 atc atc gcc gaa gaa gaa ctc gac atc gcc ttt tcc atc atg gtc cgg 403 Ile Ile Ala Glu Glu Glu Leu Asp Ile Ala Phe Ser Ile Met Val Arg 90 95 100 cca ggg act tcg ctt gcc gac gtc aaa acc ctc gcc acc cac ccg gtt 451 Pro Gly Thr Ser Leu Ala Asp Val Lys Thr Leu Ala Thr His Pro Val 105 110 115 ggg tac caa caa gtg aaa aac tgg atg gca acc acc att ccg gac gcc 499 Gly Tyr Gln Gln Val Lys Asn Trp Met Ala Thr Thr Ile Pro Asp Ala 120 125 130 atg tat ctt tca gca agc tcc aac ggc gcc ggc gca caa atg gtt gcc 547 Met Tyr Leu Ser Ala Ser Ser Asn Gly Ala Gly Ala Gln Met Val Ala 135 140 145 gaa gga acc gcc gac gca gcc gca gcg ccc tcc cgc gca gcc gaa ctc 595 Glu Gly Thr Ala Asp Ala Ala Ala Ala Pro Ser Arg Ala Ala Glu Leu 150 155 160 165 ttc gga ctg gaa cgc ctt gtt gat gat gtc gcc gac gtc cgt ggc gcc 643 Phe Gly Leu Glu Arg Leu Val Asp Asp Val Ala Asp Val Arg Gly Ala 170 175 180 cgc acc cgc ttc gtt gct gtc caa gcc caa gca gcc gtt tcc gaa ccg 691 Arg Thr Arg Phe Val Ala Val Gln Ala Gln Ala Ala Val Ser Glu Pro 185 190 195 acc ggc cac gac cgc acc tcc gtc att ttc tcc cta ccg aat gtg cca 739 Thr Gly His Asp Arg Thr Ser Val Ile Phe Ser Leu Pro Asn Val Pro 200 205 210 ggc agc ctc gtg cgc gcc ctc aac gaa ttc gcc atc cgc ggc gtt gac 787 Gly Ser Leu Val Arg Ala Leu Asn Glu Phe Ala Ile Arg Gly Val Asp 215 220 225 ctc acc cgc atc gaa tcc cgc ccc acc cgc aaa gtc ttc gga acc tac 835 Leu Thr Arg Ile Glu Ser Arg Pro Thr Arg Lys Val Phe Gly Thr Tyr 230 235 240 245 cgc ttc cac ctg gac ata tcc gga cat atc cgc gat atc ccc gtc gcc 883 Arg Phe His Leu Asp Ile Ser Gly His Ile Arg Asp Ile Pro Val Ala 250 255 260 gaa gcc ctc cgc gca ctc cac ctc caa gcc gaa gaa ctc gtc ttc gtc 931 Glu Ala Leu Arg Ala Leu His Leu Gln Ala Glu Glu Leu Val Phe Val 265 270 275 ggc tcc tgg ccc tcc aac cgt gcg gaa gac agc acg ccc caa acc gac 979 Gly Ser Trp Pro Ser Asn Arg Ala Glu Asp Ser Thr Pro Gln Thr Asp 280 285 290 caa cta gct aag cta cac aag gcg gac gaa tgg gtt cgc gca gca agc 1027 Gln Leu Ala Lys Leu His Lys Ala Asp Glu Trp Val Arg Ala Ala Ser 295 300 305 gaa gga agg aaa ctt aac tagccatggc cggccggatt att 1068 Glu Gly Arg Lys Leu Asn 310 315 <210> 424 <211> 315 <212> PRT <213> Corynebacterium glutamicum <400> 424 Met Ser Asp Ala Pro Thr Val Val Ala Tyr Leu Gly Pro Ala Gly Thr 1 5 10 15 Phe Thr Glu Glu Ala Leu Tyr Lys Phe Ala Asp Ala Gly Val Phe Gly 20 25 30 Asp Gly Glu Ile Glu Gln Leu Pro Ala Lys Ser Pro Gln Glu Ala Val 35 40 45 Asp Ala Val Arg His Gly Thr Ala Gln Phe Ala Val Val Ala Ile Glu 50 55 60 Asn Phe Val Asp Gly Pro Val Thr Pro Thr Phe Asp Ala Leu Asp Gln 65 70 75 80 Gly Ser Asn Val Gln Ile Ile Ala Glu Glu Glu Leu Asp Ile Ala Phe 85 90 95 Ser Ile Met Val Arg Pro Gly Thr Ser Leu Ala Asp Val Lys Thr Leu 100 105 110 Ala Thr His Pro Val Gly Tyr Gln Gln Val Lys Asn Trp Met Ala Thr 115 120 125 Thr Ile Pro Asp Ala Met Tyr Leu Ser Ala Ser Ser Asn Gly Ala Gly 130 135 140 Ala Gln Met Val Ala Glu Gly Thr Ala Asp Ala Ala Ala Ala Pro Ser 145 150 155 160 Arg Ala Ala Glu Leu Phe Gly Leu Glu Arg Leu Val Asp Asp Val Ala 165 170 175 Asp Val Arg Gly Ala Arg Thr Arg Phe Val Ala Val Gln Ala Gln Ala 180 185 190 Ala Val Ser Glu Pro Thr Gly His Asp Arg Thr Ser Val Ile Phe Ser 195 200 205 Leu Pro Asn Val Pro Gly Ser Leu Val Arg Ala Leu Asn Glu Phe Ala 210 215 220 Ile Arg Gly Val Asp Leu Thr Arg Ile Glu Ser Arg Pro Thr Arg Lys 225 230 235 240 Val Phe Gly Thr Tyr Arg Phe His Leu Asp Ile Ser Gly His Ile Arg 245 250 255 Asp Ile Pro Val Ala Glu Ala Leu Arg Ala Leu His Leu Gln Ala Glu 260 265 270 Glu Leu Val Phe Val Gly Ser Trp Pro Ser Asn Arg Ala Glu Asp Ser 275 280 285 Thr Pro Gln Thr Asp Gln Leu Ala Lys Leu His Lys Ala Asp Glu Trp 290 295 300 Val Arg Ala Ala Ser Glu Gly Arg Lys Leu Asn 305 310 315 <210> 425 <211> 1353 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1330) <223> RXN01698 <400> 425 cgctagtgcc tgcagttatg tcgctttttg acgtcgaaaa gcaattttaa aaagcccttg 60 gggtgggctg gatacgtctt ctgcggcctt tcgtgcgata atg cta ggc atg ctt 115 Met Leu Gly Met Leu 1 5 cga tgg act aca gca ggt gaa tcc cac ggc cag gcg ctt atc gcc acg 163 Arg Trp Thr Thr Ala Gly Glu Ser His Gly Gln Ala Leu Ile Ala Thr 10 15 20 gtt gaa cac atg cca gca ggc gtg ccc gtg act aaa gat gag gtc tcg 211 Val Glu His Met Pro Ala Gly Val Pro Val Thr Lys Asp Glu Val Ser 25 30 35 tat caa ttg gcg cgc cga cgc ctt gga tat ggt cgc ggc gct cgc atg 259 Tyr Gln Leu Ala Arg Arg Arg Leu Gly Tyr Gly Arg Gly Ala Arg Met 40 45 50 aag ttt gag caa gac gcg ttg acc ttc ctc acc ggc atc cgc cac ggc 307 Lys Phe Glu Gln Asp Ala Leu Thr Phe Leu Thr Gly Ile Arg His Gly 55 60 65 ctc act ttg ggt agc ccc atc tca atc atg atc ggc aac act gag tgg 355 Leu Thr Leu Gly Ser Pro Ile Ser Ile Met Ile Gly Asn Thr Glu Trp 70 75 80 85 gat aag tgg acc acc atc atg tcc tct gac gct ttg gac atg gaa gac 403 Asp Lys Trp Thr Thr Ile Met Ser Ser Asp Ala Leu Asp Met Glu Asp 90 95 100 cca gat aac gtt gcg gcg atg tct tcg ggt cgg ggc gca aaa ctg act 451 Pro Asp Asn Val Ala Ala Met Ser Ser Gly Arg Gly Ala Lys Leu Thr 105 110 115 cgt ccg cgt cca ggc cac gct gat tac gca ggc atg ctc aag tac gga 499 Arg Pro Arg Pro Gly His Ala Asp Tyr Ala Gly Met Leu Lys Tyr Gly 120 125 130 ttc gat gat gcc cgc aac gtg ctg gag cgt tct tca gcc cgt gag acg 547 Phe Asp Asp Ala Arg Asn Val Leu Glu Arg Ser Ser Ala Arg Glu Thr 135 140 145 gca gca cgc gtg gca gca gca acc gtt gcg cgt tcc ttc ctg cgt gaa 595 Ala Ala Arg Val Ala Ala Ala Thr Val Ala Arg Ser Phe Leu Arg Glu 150 155 160 165 acc ttg ggc gtg gaa gtg ctt tcc cac gta att tcc att ggt gcg tcc 643 Thr Leu Gly Val Glu Val Leu Ser His Val Ile Ser Ile Gly Ala Ser 170 175 180 gag cct tac act ggc gcg gag cca acc ttt gca gat att caa gca atc 691 Glu Pro Tyr Thr Gly Ala Glu Pro Thr Phe Ala Asp Ile Gln Ala Ile 185 190 195 gat gat tcc cca gtt cgt gca ttc ggt aaa gac gct gaa gaa tcc atg 739 Asp Asp Ser Pro Val Arg Ala Phe Gly Lys Asp Ala Glu Glu Ser Met 200 205 210 atc gcg gaa atc gag gcc gca aag aaa gcc ggc gat acc ctc ggt ggc 787 Ile Ala Glu Ile Glu Ala Ala Lys Lys Ala Gly Asp Thr Leu Gly Gly 215 220 225 atc gtg gaa gtg att gtt gaa ggc ctg ccc atc ggt ttg ggc tca cac 835 Ile Val Glu Val Ile Val Glu Gly Leu Pro Ile Gly Leu Gly Ser His 230 235 240 245 att tct ggc gaa gat cgc ctc gat gcg cag atc gca gct gca ctc atg 883 Ile Ser Gly Glu Asp Arg Leu Asp Ala Gln Ile Ala Ala Ala Leu Met 250 255 260 ggc att cag gcc atc aag ggc gtg gaa atc ggt gac ggt ttc gaa gaa 931 Gly Ile Gln Ala Ile Lys Gly Val Glu Ile Gly Asp Gly Phe Glu Glu 265 270 275 gct cgt cga cgt ggc tcc gaa gcc cac gat gaa gtg ttc ctg gat gac 979 Ala Arg Arg Arg Gly Ser Glu Ala His Asp Glu Val Phe Leu Asp Asp 280 285 290 aac ggc gta tac cgc aac acc aac cgt gca ggt ggc ctc gaa ggc ggc 1027 Asn Gly Val Tyr Arg Asn Thr Asn Arg Ala Gly Gly Leu Glu Gly Gly 295 300 305 atg acc aac ggt gaa acc ctg cgc gtt cgt gct ggc atg aag cca att 1075 Met Thr Asn Gly Glu Thr Leu Arg Val Arg Ala Gly Met Lys Pro Ile 310 315 320 325 tct act gtg cct cgc gcc ctg aaa acc att gat atg gaa aac ggc aag 1123 Ser Thr Val Pro Arg Ala Leu Lys Thr Ile Asp Met Glu Asn Gly Lys 330 335 340 gca gca acc gga atc cac cag cgt tcc gac gtg tgc gct gtt cca gcc 1171 Ala Ala Thr Gly Ile His Gln Arg Ser Asp Val Cys Ala Val Pro Ala 345 350 355 gcc ggt gtc gtt gca gaa gca atg gtc acc ctg gtt ctc gcc cgc gca 1219 Ala Gly Val Val Ala Glu Ala Met Val Thr Leu Val Leu Ala Arg Ala 360 365 370 gtc ctg cag aaa ttc ggc ggt gac tcc ctg agc gaa acc aag agc aac 1267 Val Leu Gln Lys Phe Gly Gly Asp Ser Leu Ser Glu Thr Lys Ser Asn 375 380 385 att gac acc tac ctc aaa aac att gag gaa cga atg aaa ttc gaa ggt 1315 Ile Asp Thr Tyr Leu Lys Asn Ile Glu Glu Arg Met Lys Phe Glu Gly 390 395 400 405 tta gag gat gga gcg taatgaagtg aatgatcaaa ttc 1353 Leu Glu Asp Gly Ala 410 <210> 426 <211> 410 <212> PRT <213> Corynebacterium glutamicum <400> 426 Met Leu Gly Met Leu Arg Trp Thr Thr Ala Gly Glu Ser His Gly Gln 1 5 10 15 Ala Leu Ile Ala Thr Val Glu His Met Pro Ala Gly Val Pro Val Thr 20 25 30 Lys Asp Glu Val Ser Tyr Gln Leu Ala Arg Arg Arg Leu Gly Tyr Gly 35 40 45 Arg Gly Ala Arg Met Lys Phe Glu Gln Asp Ala Leu Thr Phe Leu Thr 50 55 60 Gly Ile Arg His Gly Leu Thr Leu Gly Ser Pro Ile Ser Ile Met Ile 65 70 75 80 Gly Asn Thr Glu Trp Asp Lys Trp Thr Thr Ile Met Ser Ser Asp Ala 85 90 95 Leu Asp Met Glu Asp Pro Asp Asn Val Ala Ala Met Ser Ser Gly Arg 100 105 110 Gly Ala Lys Leu Thr Arg Pro Arg Pro Gly His Ala Asp Tyr Ala Gly 115 120 125 Met Leu Lys Tyr Gly Phe Asp Asp Ala Arg Asn Val Leu Glu Arg Ser 130 135 140 Ser Ala Arg Glu Thr Ala Ala Arg Val Ala Ala Ala Thr Val Ala Arg 145 150 155 160 Ser Phe Leu Arg Glu Thr Leu Gly Val Glu Val Leu Ser His Val Ile 165 170 175 Ser Ile Gly Ala Ser Glu Pro Tyr Thr Gly Ala Glu Pro Thr Phe Ala 180 185 190 Asp Ile Gln Ala Ile Asp Asp Ser Pro Val Arg Ala Phe Gly Lys Asp 195 200 205 Ala Glu Glu Ser Met Ile Ala Glu Ile Glu Ala Ala Lys Lys Ala Gly 210 215 220 Asp Thr Leu Gly Gly Ile Val Glu Val Ile Val Glu Gly Leu Pro Ile 225 230 235 240 Gly Leu Gly Ser His Ile Ser Gly Glu Asp Arg Leu Asp Ala Gln Ile 245 250 255 Ala Ala Ala Leu Met Gly Ile Gln Ala Ile Lys Gly Val Glu Ile Gly 260 265 270 Asp Gly Phe Glu Glu Ala Arg Arg Arg Gly Ser Glu Ala His Asp Glu 275 280 285 Val Phe Leu Asp Asp Asn Gly Val Tyr Arg Asn Thr Asn Arg Ala Gly 290 295 300 Gly Leu Glu Gly Gly Met Thr Asn Gly Glu Thr Leu Arg Val Arg Ala 305 310 315 320 Gly Met Lys Pro Ile Ser Thr Val Pro Arg Ala Leu Lys Thr Ile Asp 325 330 335 Met Glu Asn Gly Lys Ala Ala Thr Gly Ile His Gln Arg Ser Asp Val 340 345 350 Cys Ala Val Pro Ala Ala Gly Val Val Ala Glu Ala Met Val Thr Leu 355 360 365 Val Leu Ala Arg Ala Val Leu Gln Lys Phe Gly Gly Asp Ser Leu Ser 370 375 380 Glu Thr Lys Ser Asn Ile Asp Thr Tyr Leu Lys Asn Ile Glu Glu Arg 385 390 395 400 Met Lys Phe Glu Gly Leu Glu Asp Gly Ala 405 410 <210> 427 <211> 1013 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(990) <223> FRXA01698 <400> 427 ggc aac act gag tgg gat aag tgg acc acc atc atg tcc tct gac gct 48 Gly Asn Thr Glu Trp Asp Lys Trp Thr Thr Ile Met Ser Ser Asp Ala 1 5 10 15 ttg gac atg gaa gac cca gat aac gtt gcg gcg atg tct tcg ggt cgg 96 Leu Asp Met Glu Asp Pro Asp Asn Val Ala Ala Met Ser Ser Gly Arg 20 25 30 ggc gca aaa ctg act cgt ccg cgt cca ggc cac gct gat tac gca ggc 144 Gly Ala Lys Leu Thr Arg Pro Arg Pro Gly His Ala Asp Tyr Ala Gly 35 40 45 atg ctc aag tac gga ttc gat gat gcc cgc aac gtg ctg gag cgt tct 192 Met Leu Lys Tyr Gly Phe Asp Asp Ala Arg Asn Val Leu Glu Arg Ser 50 55 60 tca gcc cgt gag acg gca gca cgc gtg gca gca gca acc gtt gcg cgt 240 Ser Ala Arg Glu Thr Ala Ala Arg Val Ala Ala Ala Thr Val Ala Arg 65 70 75 80 tcc ttc ctg cgt gaa acc ttg ggc gtg gaa gtg ctt tcc cac gta att 288 Ser Phe Leu Arg Glu Thr Leu Gly Val Glu Val Leu Ser His Val Ile 85 90 95 tcc att ggt gcg tcc gag cct tac act ggc gcg gag cca acc ttt gca 336 Ser Ile Gly Ala Ser Glu Pro Tyr Thr Gly Ala Glu Pro Thr Phe Ala 100 105 110 gat att caa gca atc gat gat tcc cca gtt cgt gca ttc ggt aaa gac 384 Asp Ile Gln Ala Ile Asp Asp Ser Pro Val Arg Ala Phe Gly Lys Asp 115 120 125 gct gaa gaa tcc atg atc gcg gaa atc gag gcc gca aag aaa gcc ggc 432 Ala Glu Glu Ser Met Ile Ala Glu Ile Glu Ala Ala Lys Lys Ala Gly 130 135 140 gat acc ctc ggt ggc atc gtg gaa gtg att gtt gaa ggc ctg ccc atc 480 Asp Thr Leu Gly Gly Ile Val Glu Val Ile Val Glu Gly Leu Pro Ile 145 150 155 160 ggt ttg ggc tca cac att tct ggc gaa gat cgc ctc gat gcg cag atc 528 Gly Leu Gly Ser His Ile Ser Gly Glu Asp Arg Leu Asp Ala Gln Ile 165 170 175 gca gct gca ctc atg ggc att cag gcc atc aag ggc gtg gaa atc ggt 576 Ala Ala Ala Leu Met Gly Ile Gln Ala Ile Lys Gly Val Glu Ile Gly 180 185 190 gac ggt ttc gaa gaa gct cgt cga cgt ggc tcc gaa gcc cac gat gaa 624 Asp Gly Phe Glu Glu Ala Arg Arg Arg Gly Ser Glu Ala His Asp Glu 195 200 205 gtg ttc ctg gat gac aac ggc gta tac cgc aac acc aac cgt gca ggt 672 Val Phe Leu Asp Asp Asn Gly Val Tyr Arg Asn Thr Asn Arg Ala Gly 210 215 220 ggc ctc gaa ggc ggc atg acc aac ggt gaa acc ctg cgc gtt cgt gct 720 Gly Leu Glu Gly Gly Met Thr Asn Gly Glu Thr Leu Arg Val Arg Ala 225 230 235 240 ggc atg aag cca att tct act gtg cct cgc gcc ctg aaa acc att gat 768 Gly Met Lys Pro Ile Ser Thr Val Pro Arg Ala Leu Lys Thr Ile Asp 245 250 255 atg gaa aac ggc aag gca gca acc gga atc cac cag cgt tcc gac gtg 816 Met Glu Asn Gly Lys Ala Ala Thr Gly Ile His Gln Arg Ser Asp Val 260 265 270 tgc gct gtt cca gcc gcc ggt gtc gtt gca gaa gca atg gtc acc ctg 864 Cys Ala Val Pro Ala Ala Gly Val Val Ala Glu Ala Met Val Thr Leu 275 280 285 gtt ctc gcc cgc gca gtc ctg cag aaa ttc ggc ggt gac tcc ctg agc 912 Val Leu Ala Arg Ala Val Leu Gln Lys Phe Gly Gly Asp Ser Leu Ser 290 295 300 gaa acc aag agc aac att gac acc tac ctc aaa aac att gag gaa cga 960 Glu Thr Lys Ser Asn Ile Asp Thr Tyr Leu Lys Asn Ile Glu Glu Arg 305 310 315 320 atg aaa ttc gaa ggt tta gag gat gga gcg taatgaagtg aatgatcaaa 1010 Met Lys Phe Glu Gly Leu Glu Asp Gly Ala 325 330 ttc 1013 <210> 428 <211> 330 <212> PRT <213> Corynebacterium glutamicum <400> 428 Gly Asn Thr Glu Trp Asp Lys Trp Thr Thr Ile Met Ser Ser Asp Ala 1 5 10 15 Leu Asp Met Glu Asp Pro Asp Asn Val Ala Ala Met Ser Ser Gly Arg 20 25 30 Gly Ala Lys Leu Thr Arg Pro Arg Pro Gly His Ala Asp Tyr Ala Gly 35 40 45 Met Leu Lys Tyr Gly Phe Asp Asp Ala Arg Asn Val Leu Glu Arg Ser 50 55 60 Ser Ala Arg Glu Thr Ala Ala Arg Val Ala Ala Ala Thr Val Ala Arg 65 70 75 80 Ser Phe Leu Arg Glu Thr Leu Gly Val Glu Val Leu Ser His Val Ile 85 90 95 Ser Ile Gly Ala Ser Glu Pro Tyr Thr Gly Ala Glu Pro Thr Phe Ala 100 105 110 Asp Ile Gln Ala Ile Asp Asp Ser Pro Val Arg Ala Phe Gly Lys Asp 115 120 125 Ala Glu Glu Ser Met Ile Ala Glu Ile Glu Ala Ala Lys Lys Ala Gly 130 135 140 Asp Thr Leu Gly Gly Ile Val Glu Val Ile Val Glu Gly Leu Pro Ile 145 150 155 160 Gly Leu Gly Ser His Ile Ser Gly Glu Asp Arg Leu Asp Ala Gln Ile 165 170 175 Ala Ala Ala Leu Met Gly Ile Gln Ala Ile Lys Gly Val Glu Ile Gly 180 185 190 Asp Gly Phe Glu Glu Ala Arg Arg Arg Gly Ser Glu Ala His Asp Glu 195 200 205 Val Phe Leu Asp Asp Asn Gly Val Tyr Arg Asn Thr Asn Arg Ala Gly 210 215 220 Gly Leu Glu Gly Gly Met Thr Asn Gly Glu Thr Leu Arg Val Arg Ala 225 230 235 240 Gly Met Lys Pro Ile Ser Thr Val Pro Arg Ala Leu Lys Thr Ile Asp 245 250 255 Met Glu Asn Gly Lys Ala Ala Thr Gly Ile His Gln Arg Ser Asp Val 260 265 270 Cys Ala Val Pro Ala Ala Gly Val Val Ala Glu Ala Met Val Thr Leu 275 280 285 Val Leu Ala Arg Ala Val Leu Gln Lys Phe Gly Gly Asp Ser Leu Ser 290 295 300 Glu Thr Lys Ser Asn Ile Asp Thr Tyr Leu Lys Asn Ile Glu Glu Arg 305 310 315 320 Met Lys Phe Glu Gly Leu Glu Asp Gly Ala 325 330 <210> 429 <211> 906 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(883) <223> RXA01095 <400> 429 gaaaccccag gtcaaagcta gggtgtggca ccctgatttc tttcgccatg tgtgttcggg 60 ataaccttaa acacagcatt ggttggaagg aggttggggc atg gtt gca aca gag 115 Met Val Ala Thr Glu 1 5 aac cgc atg ttg atg gaa atc gct gcg gaa ata tcg gct cgg gaa gca 163 Asn Arg Met Leu Met Glu Ile Ala Ala Glu Ile Ser Ala Arg Glu Ala 10 15 20 acg ctt ggt ttt caa gaa gtc aaa act aaa tct cga tca gca ggt ctc 211 Thr Leu Gly Phe Gln Glu Val Lys Thr Lys Ser Arg Ser Ala Gly Leu 25 30 35 acg gcg gct ttc gat att gct tca gtc ttt ttt tcg tct gga tgt aat 259 Thr Ala Ala Phe Asp Ile Ala Ser Val Phe Phe Ser Ser Gly Cys Asn 40 45 50 gtc gta gtc gcc ttt gat cgt ttt gca tcc aat tgg tct gat cat tcg 307 Val Val Val Ala Phe Asp Arg Phe Ala Ser Asn Trp Ser Asp His Ser 55 60 65 gat cat gtg gac tac gct gca cag gtt gcg ggt ttt ggc gca tca atg 355 Asp His Val Asp Tyr Ala Ala Gln Val Ala Gly Phe Gly Ala Ser Met 70 75 80 85 ctt gca tat acg gtg cgc agg gga cag ttt gat acc gca gta cgc gat 403 Leu Ala Tyr Thr Val Arg Arg Gly Gln Phe Asp Thr Ala Val Arg Asp 90 95 100 atc agg gac atc aaa tct gaa gta gac att ccc att ctg ctt cat gat 451 Ile Arg Asp Ile Lys Ser Glu Val Asp Ile Pro Ile Leu Leu His Asp 105 110 115 ccc atc atc gat ccg tat caa atc cac gaa gcc cgc gtc atg ggc atc 499 Pro Ile Ile Asp Pro Tyr Gln Ile His Glu Ala Arg Val Met Gly Ile 120 125 130 gac gct ctt caa ttc ccc gta tgg gcg atg gaa caa gct cga ctg gaa 547 Asp Ala Leu Gln Phe Pro Val Trp Ala Met Glu Gln Ala Arg Leu Glu 135 140 145 tct ttg gtg gac cgc acc gaa tca ttg ggc atg aca gcc atc gtg tct 595 Ser Leu Val Asp Arg Thr Glu Ser Leu Gly Met Thr Ala Ile Val Ser 150 155 160 165 gtg cga aac cac gaa gaa gcg cat cgt gca gtg gac gca gga gcg aca 643 Val Arg Asn His Glu Glu Ala His Arg Ala Val Asp Ala Gly Ala Thr 170 175 180 gtg gta gca att gat att act ggt tat acc ggc tca ctc act ttg cct 691 Val Val Ala Ile Asp Ile Thr Gly Tyr Thr Gly Ser Leu Thr Leu Pro 185 190 195 gaa gcg ttt tcg ggt atc acc caa ttc atg ccc aaa gag gta gcc cgc 739 Glu Ala Phe Ser Gly Ile Thr Gln Phe Met Pro Lys Glu Val Ala Arg 200 205 210 att gtg ctc gga ggt tgc agc agc cct aaa gaa ctc atg cgg ttt gca 787 Ile Val Leu Gly Gly Cys Ser Ser Pro Lys Glu Leu Met Arg Phe Ala 215 220 225 cga cat tct gca gac gcc atc ttt gtt cca cat gca gac ctc gcc acc 835 Arg His Ser Ala Asp Ala Ile Phe Val Pro His Ala Asp Leu Ala Thr 230 235 240 245 aca aaa tct ctt gtg aca gca ggt atg cat cca gcg tgc cca tcg cgt 883 Thr Lys Ser Leu Val Thr Ala Gly Met His Pro Ala Cys Pro Ser Arg 250 255 260 tgaagaggtg ctctgtggtc agc 906 <210> 430 <211> 261 <212> PRT <213> Corynebacterium glutamicum <400> 430 Met Val Ala Thr Glu Asn Arg Met Leu Met Glu Ile Ala Ala Glu Ile 1 5 10 15 Ser Ala Arg Glu Ala Thr Leu Gly Phe Gln Glu Val Lys Thr Lys Ser 20 25 30 Arg Ser Ala Gly Leu Thr Ala Ala Phe Asp Ile Ala Ser Val Phe Phe 35 40 45 Ser Ser Gly Cys Asn Val Val Val Ala Phe Asp Arg Phe Ala Ser Asn 50 55 60 Trp Ser Asp His Ser Asp His Val Asp Tyr Ala Ala Gln Val Ala Gly 65 70 75 80 Phe Gly Ala Ser Met Leu Ala Tyr Thr Val Arg Arg Gly Gln Phe Asp 85 90 95 Thr Ala Val Arg Asp Ile Arg Asp Ile Lys Ser Glu Val Asp Ile Pro 100 105 110 Ile Leu Leu His Asp Pro Ile Ile Asp Pro Tyr Gln Ile His Glu Ala 115 120 125 Arg Val Met Gly Ile Asp Ala Leu Gln Phe Pro Val Trp Ala Met Glu 130 135 140 Gln Ala Arg Leu Glu Ser Leu Val Asp Arg Thr Glu Ser Leu Gly Met 145 150 155 160 Thr Ala Ile Val Ser Val Arg Asn His Glu Glu Ala His Arg Ala Val 165 170 175 Asp Ala Gly Ala Thr Val Val Ala Ile Asp Ile Thr Gly Tyr Thr Gly 180 185 190 Ser Leu Thr Leu Pro Glu Ala Phe Ser Gly Ile Thr Gln Phe Met Pro 195 200 205 Lys Glu Val Ala Arg Ile Val Leu Gly Gly Cys Ser Ser Pro Lys Glu 210 215 220 Leu Met Arg Phe Ala Arg His Ser Ala Asp Ala Ile Phe Val Pro His 225 230 235 240 Ala Asp Leu Ala Thr Thr Lys Ser Leu Val Thr Ala Gly Met His Pro 245 250 255 Ala Cys Pro Ser Arg 260 <210> 431 <211> 1545 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1522) <223> RXA00955 <400> 431 gatggtgcac aaaaggcgct ttccttgctt gccgacggca ccacccaggc atggttggcc 60 aagcacgaag agatcgatta ctcagaaaag gagtcttcca atg act agt aat aat 115 Met Thr Ser Asn Asn 1 5 ctg ccc aca gtg ttg gaa agc atc gtc gag ggt cgt cgc gga cac ctg 163 Leu Pro Thr Val Leu Glu Ser Ile Val Glu Gly Arg Arg Gly His Leu 10 15 20 gag gaa att cgc gct cgc atc gct cac gtg gat gtg gat gcg ctt cca 211 Glu Glu Ile Arg Ala Arg Ile Ala His Val Asp Val Asp Ala Leu Pro 25 30 35 aaa tcc acc cgt tct ctg ttt gat tcc ctc aac cag ggt agg gga ggg 259 Lys Ser Thr Arg Ser Leu Phe Asp Ser Leu Asn Gln Gly Arg Gly Gly 40 45 50 gcg cgt ttc atc atg gag tgc aag tcc gca tcg cct tct ttg gga atg 307 Ala Arg Phe Ile Met Glu Cys Lys Ser Ala Ser Pro Ser Leu Gly Met 55 60 65 att cgt gag cac tac cag ccg ggt gaa atc gct cgc gtg tac tct cgc 355 Ile Arg Glu His Tyr Gln Pro Gly Glu Ile Ala Arg Val Tyr Ser Arg 70 75 80 85 tac gcc agc ggc att tcc gtg ctg tgc gag ccg gat cgt ttt ggt ggc 403 Tyr Ala Ser Gly Ile Ser Val Leu Cys Glu Pro Asp Arg Phe Gly Gly 90 95 100 gat tac gat cac ctc gct acc gtt gcc gct acc tct cat ctt ccg gtg 451 Asp Tyr Asp His Leu Ala Thr Val Ala Ala Thr Ser His Leu Pro Val 105 110 115 ctg tgc aaa gac ttc atc att gat cct gtc cag gta cac gcg gcg cgt 499 Leu Cys Lys Asp Phe Ile Ile Asp Pro Val Gln Val His Ala Ala Arg 120 125 130 tac ttt ggt gct gat gcc atc ctg ctc atg ctc tct gtg ctt gat gat 547 Tyr Phe Gly Ala Asp Ala Ile Leu Leu Met Leu Ser Val Leu Asp Asp 135 140 145 gaa gag tac gca gca ctc gct gcc gag gct gcg cgt ttt gat ctg gat 595 Glu Glu Tyr Ala Ala Leu Ala Ala Glu Ala Ala Arg Phe Asp Leu Asp 150 155 160 165 atc ctc acc gag gtt att gat gag gag gaa gtc gcc cgc gcc atc aag 643 Ile Leu Thr Glu Val Ile Asp Glu Glu Glu Val Ala Arg Ala Ile Lys 170 175 180 ctg ggt gcg aag atc ttt ggc gtc aac cac cgc aac ctg cat gat ctg 691 Leu Gly Ala Lys Ile Phe Gly Val Asn His Arg Asn Leu His Asp Leu 185 190 195 tcc att gat ttg gat cgt tca cgt cgc ctg tcc aag ctc att cca gca 739 Ser Ile Asp Leu Asp Arg Ser Arg Arg Leu Ser Lys Leu Ile Pro Ala 200 205 210 gat gcc gtg ctc gtg tct gag tct ggc gtg cgc gat acc gaa acc gtc 787 Asp Ala Val Leu Val Ser Glu Ser Gly Val Arg Asp Thr Glu Thr Val 215 220 225 cgc cag cta ggt ggg cac tcc aat gca ttc ctc gtt ggc tcc cag ctg 835 Arg Gln Leu Gly Gly His Ser Asn Ala Phe Leu Val Gly Ser Gln Leu 230 235 240 245 acc agc cag gaa aac gtc gat ctg gca gcc cgc gaa tta gtc tac ggc 883 Thr Ser Gln Glu Asn Val Asp Leu Ala Ala Arg Glu Leu Val Tyr Gly 250 255 260 ccc aac aaa gtc tgc gga ctc acc tca cca agt gca gca caa acc gct 931 Pro Asn Lys Val Cys Gly Leu Thr Ser Pro Ser Ala Ala Gln Thr Ala 265 270 275 cgc gca gcg ggt gcg gtc tac ggc ggg ctc atc ttc gaa gag gca tcg 979 Arg Ala Ala Gly Ala Val Tyr Gly Gly Leu Ile Phe Glu Glu Ala Ser 280 285 290 cca cgc aat gtt tca cgt gaa aca ttg caa aaa atc atc gcc gca gag 1027 Pro Arg Asn Val Ser Arg Glu Thr Leu Gln Lys Ile Ile Ala Ala Glu 295 300 305 ccc aac ctg cgc tac gtc gcg gtc agc cgt cgc acc tcc ggg tac aag 1075 Pro Asn Leu Arg Tyr Val Ala Val Ser Arg Arg Thr Ser Gly Tyr Lys 310 315 320 325 gat ttg ctt gtc gac ggc atc ttc gcc gta caa atc cac gcc cca ctg 1123 Asp Leu Leu Val Asp Gly Ile Phe Ala Val Gln Ile His Ala Pro Leu 330 335 340 cag gac agc gtc gaa gca gaa aag gca ttg atc gcc gcc gtt cgt gaa 1171 Gln Asp Ser Val Glu Ala Glu Lys Ala Leu Ile Ala Ala Val Arg Glu 345 350 355 gag gtt gga ccg cag gtc cag gtc tgg cgc gcg atc tcg atg tcc agc 1219 Glu Val Gly Pro Gln Val Gln Val Trp Arg Ala Ile Ser Met Ser Ser 360 365 370 ccc ttg ggg gct gaa gtg gca gct gcg gtg gag ggt gac gtc gat aag 1267 Pro Leu Gly Ala Glu Val Ala Ala Ala Val Glu Gly Asp Val Asp Lys 375 380 385 cta att ctt gat gcc cat gaa ggt ggc agc ggg gaa gta ttc gac tgg 1315 Leu Ile Leu Asp Ala His Glu Gly Gly Ser Gly Glu Val Phe Asp Trp 390 395 400 405 gct acg gtg ccg gcc gct gtg aag gca aag tct ttg ctc gcg gga ggc 1363 Ala Thr Val Pro Ala Ala Val Lys Ala Lys Ser Leu Leu Ala Gly Gly 410 415 420 atc tct ccg gac aac gct gcg cag gca ctc gct gtg ggc tgc gca ggt 1411 Ile Ser Pro Asp Asn Ala Ala Gln Ala Leu Ala Val Gly Cys Ala Gly 425 430 435 ttg gac atc aac tct ggc gtg gaa tac ccc gcc ggt gca ggc acg tgg 1459 Leu Asp Ile Asn Ser Gly Val Glu Tyr Pro Ala Gly Ala Gly Thr Trp 440 445 450 gct ggg gcg aaa gac gcc ggc gcg ctg ctg aaa att tta gcg acc atc 1507 Ala Gly Ala Lys Asp Ala Gly Ala Leu Leu Lys Ile Leu Ala Thr Ile 455 460 465 tcc aca ttc cat tac taaaggttta aataggatca tga 1545 Ser Thr Phe His Tyr 470 <210> 432 <211> 474 <212> PRT <213> Corynebacterium glutamicum <400> 432 Met Thr Ser Asn Asn Leu Pro Thr Val Leu Glu Ser Ile Val Glu Gly 1 5 10 15 Arg Arg Gly His Leu Glu Glu Ile Arg Ala Arg Ile Ala His Val Asp 20 25 30 Val Asp Ala Leu Pro Lys Ser Thr Arg Ser Leu Phe Asp Ser Leu Asn 35 40 45 Gln Gly Arg Gly Gly Ala Arg Phe Ile Met Glu Cys Lys Ser Ala Ser 50 55 60 Pro Ser Leu Gly Met Ile Arg Glu His Tyr Gln Pro Gly Glu Ile Ala 65 70 75 80 Arg Val Tyr Ser Arg Tyr Ala Ser Gly Ile Ser Val Leu Cys Glu Pro 85 90 95 Asp Arg Phe Gly Gly Asp Tyr Asp His Leu Ala Thr Val Ala Ala Thr 100 105 110 Ser His Leu Pro Val Leu Cys Lys Asp Phe Ile Ile Asp Pro Val Gln 115 120 125 Val His Ala Ala Arg Tyr Phe Gly Ala Asp Ala Ile Leu Leu Met Leu 130 135 140 Ser Val Leu Asp Asp Glu Glu Tyr Ala Ala Leu Ala Ala Glu Ala Ala 145 150 155 160 Arg Phe Asp Leu Asp Ile Leu Thr Glu Val Ile Asp Glu Glu Glu Val 165 170 175 Ala Arg Ala Ile Lys Leu Gly Ala Lys Ile Phe Gly Val Asn His Arg 180 185 190 Asn Leu His Asp Leu Ser Ile Asp Leu Asp Arg Ser Arg Arg Leu Ser 195 200 205 Lys Leu Ile Pro Ala Asp Ala Val Leu Val Ser Glu Ser Gly Val Arg 210 215 220 Asp Thr Glu Thr Val Arg Gln Leu Gly Gly His Ser Asn Ala Phe Leu 225 230 235 240 Val Gly Ser Gln Leu Thr Ser Gln Glu Asn Val Asp Leu Ala Ala Arg 245 250 255 Glu Leu Val Tyr Gly Pro Asn Lys Val Cys Gly Leu Thr Ser Pro Ser 260 265 270 Ala Ala Gln Thr Ala Arg Ala Ala Gly Ala Val Tyr Gly Gly Leu Ile 275 280 285 Phe Glu Glu Ala Ser Pro Arg Asn Val Ser Arg Glu Thr Leu Gln Lys 290 295 300 Ile Ile Ala Ala Glu Pro Asn Leu Arg Tyr Val Ala Val Ser Arg Arg 305 310 315 320 Thr Ser Gly Tyr Lys Asp Leu Leu Val Asp Gly Ile Phe Ala Val Gln 325 330 335 Ile His Ala Pro Leu Gln Asp Ser Val Glu Ala Glu Lys Ala Leu Ile 340 345 350 Ala Ala Val Arg Glu Glu Val Gly Pro Gln Val Gln Val Trp Arg Ala 355 360 365 Ile Ser Met Ser Ser Pro Leu Gly Ala Glu Val Ala Ala Ala Val Glu 370 375 380 Gly Asp Val Asp Lys Leu Ile Leu Asp Ala His Glu Gly Gly Ser Gly 385 390 395 400 Glu Val Phe Asp Trp Ala Thr Val Pro Ala Ala Val Lys Ala Lys Ser 405 410 415 Leu Leu Ala Gly Gly Ile Ser Pro Asp Asn Ala Ala Gln Ala Leu Ala 420 425 430 Val Gly Cys Ala Gly Leu Asp Ile Asn Ser Gly Val Glu Tyr Pro Ala 435 440 445 Gly Ala Gly Thr Trp Ala Gly Ala Lys Asp Ala Gly Ala Leu Leu Lys 450 455 460 Ile Leu Ala Thr Ile Ser Thr Phe His Tyr 465 470 <210> 433 <211> 494 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(471) <223> RXA02814 <400> 433 gcc aaa aac cta gaa gaa cac tcc tac gtg gtc aac cac ctg cgc acc 48 Ala Lys Asn Leu Glu Glu His Ser Tyr Val Val Asn His Leu Arg Thr 1 5 10 15 atc ctg gaa cca ctg tgc tca caa ttc gac gcc cca aca gtt cct gaa 96 Ile Leu Glu Pro Leu Cys Ser Gln Phe Asp Ala Pro Thr Val Pro Glu 20 25 30 ctg acc aaa acc aac gaa atg tgg cac ctc gca aca ccc atc gtt ggc 144 Leu Thr Lys Thr Asn Glu Met Trp His Leu Ala Thr Pro Ile Val Gly 35 40 45 acc ctc aag tac cca cac atc acc gca cta gaa cta gcc ata cga aca 192 Thr Leu Lys Tyr Pro His Ile Thr Ala Leu Glu Leu Ala Ile Arg Thr 50 55 60 cac ccc acc ccc gcg atc tgt ggc acc ccc acc gac gcc gcc gaa gcc 240 His Pro Thr Pro Ala Ile Cys Gly Thr Pro Thr Asp Ala Ala Glu Ala 65 70 75 80 ctc atc atc gaa gcg gaa tcc ccc cga aac ttc tac gcc gga gca gcc 288 Leu Ile Ile Glu Ala Glu Ser Pro Arg Asn Phe Tyr Ala Gly Ala Ala 85 90 95 ggc tgg tgt gac tcc acc gga gac ggc gaa tac atg gta gcc atc cgc 336 Gly Trp Cys Asp Ser Thr Gly Asp Gly Glu Tyr Met Val Ala Ile Arg 100 105 110 tgc gcc gaa gta tcc gaa gac gga acc tgg gcc aga gca tgg gca ggc 384 Cys Ala Glu Val Ser Glu Asp Gly Thr Trp Ala Arg Ala Trp Ala Gly 115 120 125 gga ggc atc gtc gcc gaa tca gac gcc caa gaa gag ttt gat gaa acc 432 Gly Gly Ile Val Ala Glu Ser Asp Ala Gln Glu Glu Phe Asp Glu Thr 130 135 140 acc gcg aag ctc caa acc atc atg cgc tcg ctt ggt ttg tgagatgtgg 481 Thr Ala Lys Leu Gln Thr Ile Met Arg Ser Leu Gly Leu 145 150 155 tcttaaaaca ccg 494 <210> 434 <211> 157 <212> PRT <213> Corynebacterium glutamicum <400> 434 Ala Lys Asn Leu Glu Glu His Ser Tyr Val Val Asn His Leu Arg Thr 1 5 10 15 Ile Leu Glu Pro Leu Cys Ser Gln Phe Asp Ala Pro Thr Val Pro Glu 20 25 30 Leu Thr Lys Thr Asn Glu Met Trp His Leu Ala Thr Pro Ile Val Gly 35 40 45 Thr Leu Lys Tyr Pro His Ile Thr Ala Leu Glu Leu Ala Ile Arg Thr 50 55 60 His Pro Thr Pro Ala Ile Cys Gly Thr Pro Thr Asp Ala Ala Glu Ala 65 70 75 80 Leu Ile Ile Glu Ala Glu Ser Pro Arg Asn Phe Tyr Ala Gly Ala Ala 85 90 95 Gly Trp Cys Asp Ser Thr Gly Asp Gly Glu Tyr Met Val Ala Ile Arg 100 105 110 Cys Ala Glu Val Ser Glu Asp Gly Thr Trp Ala Arg Ala Trp Ala Gly 115 120 125 Gly Gly Ile Val Ala Glu Ser Asp Ala Gln Glu Glu Phe Asp Glu Thr 130 135 140 Thr Ala Lys Leu Gln Thr Ile Met Arg Ser Leu Gly Leu 145 150 155 <210> 435 <211> 803 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(780) <223> RXA00229 <400> 435 gag gcg aaa ggc ctc gcg cag gga cgt gcg acg gtg tac agg cgc atc 48 Glu Ala Lys Gly Leu Ala Gln Gly Arg Ala Thr Val Tyr Arg Arg Ile 1 5 10 15 gac acg ctt ggg tcg cgt gct tcc ggg caa gat tta aat acg ctt ctc 96 Asp Thr Leu Gly Ser Arg Ala Ser Gly Gln Asp Leu Asn Thr Leu Leu 20 25 30 gac gcc gcc ctc tac ctt ggc ttc agc ggc ctg aac atc act cac ccg 144 Asp Ala Ala Leu Tyr Leu Gly Phe Ser Gly Leu Asn Ile Thr His Pro 35 40 45 tac aag caa gca gta tta ccc ctg ctt ggc gaa gtc tcc gaa caa gcc 192 Tyr Lys Gln Ala Val Leu Pro Leu Leu Gly Glu Val Ser Glu Gln Ala 50 55 60 acc caa ctc ggc gca gtg aat act gtc gtt atg gac gcc acc ggc cac 240 Thr Gln Leu Gly Ala Val Asn Thr Val Val Met Asp Ala Thr Gly His 65 70 75 80 acc acc ggc cac aac acc gac gtc tcc gga ttt ggc cgc gga atg gaa 288 Thr Thr Gly His Asn Thr Asp Val Ser Gly Phe Gly Arg Gly Met Glu 85 90 95 gaa ggc ctc ccc aac gcc aag ctc gat tcc gtc gtg cag gtc ggc gcc 336 Glu Gly Leu Pro Asn Ala Lys Leu Asp Ser Val Val Gln Val Gly Ala 100 105 110 ggc ggc gta gaa aac gca gtg gca tac gcc ctg gtc acc cac ggt gtg 384 Gly Gly Val Glu Asn Ala Val Ala Tyr Ala Leu Val Thr His Gly Val 115 120 125 cag aaa ctt cag gtc gct gac ctc gac act tcc cgc gcg cag gca ctg 432 Gln Lys Leu Gln Val Ala Asp Leu Asp Thr Ser Arg Ala Gln Ala Leu 130 135 140 gca gat gtc atc aac aac gca gtc ggc cgt gaa gcc gtc gtg gga gta 480 Ala Asp Val Ile Asn Asn Ala Val Gly Arg Glu Ala Val Val Gly Val 145 150 155 160 gac gcc cgc ggc atc gaa gac gtc atc gcc gcc gcc gac gga gta gtc 528 Asp Ala Arg Gly Ile Glu Asp Val Ile Ala Ala Ala Asp Gly Val Val 165 170 175 aac gca acc ccc atg gga atg cca gca cac ccc ggc acc gcc ttt gat 576 Asn Ala Thr Pro Met Gly Met Pro Ala His Pro Gly Thr Ala Phe Asp 180 185 190 gtc agc tgc ctc acc aag gat cac tgg gtt ggc gac gtc gtg tac atg 624 Val Ser Cys Leu Thr Lys Asp His Trp Val Gly Asp Val Val Tyr Met 195 200 205 ccc atc gaa act gaa ctt ctc aaa gcc gcc cgt gcc ctc ggc tgc gaa 672 Pro Ile Glu Thr Glu Leu Leu Lys Ala Ala Arg Ala Leu Gly Cys Glu 210 215 220 acc ctc gac gga acc cgc atg gca atc cac caa gcc gtc gat gcc ttc 720 Thr Leu Asp Gly Thr Arg Met Ala Ile His Gln Ala Val Asp Ala Phe 225 230 235 240 cga ctg ttc acc ggc ctc gaa ccc gac gtc tcc cgc atg cgg gaa act 768 Arg Leu Phe Thr Gly Leu Glu Pro Asp Val Ser Arg Met Arg Glu Thr 245 250 255 ttc ctg tcc ctc taaaagagtc agtaaaacct cga 803 Phe Leu Ser Leu 260 <210> 436 <211> 260 <212> PRT <213> Corynebacterium glutamicum <400> 436 Glu Ala Lys Gly Leu Ala Gln Gly Arg Ala Thr Val Tyr Arg Arg Ile 1 5 10 15 Asp Thr Leu Gly Ser Arg Ala Ser Gly Gln Asp Leu Asn Thr Leu Leu 20 25 30 Asp Ala Ala Leu Tyr Leu Gly Phe Ser Gly Leu Asn Ile Thr His Pro 35 40 45 Tyr Lys Gln Ala Val Leu Pro Leu Leu Gly Glu Val Ser Glu Gln Ala 50 55 60 Thr Gln Leu Gly Ala Val Asn Thr Val Val Met Asp Ala Thr Gly His 65 70 75 80 Thr Thr Gly His Asn Thr Asp Val Ser Gly Phe Gly Arg Gly Met Glu 85 90 95 Glu Gly Leu Pro Asn Ala Lys Leu Asp Ser Val Val Gln Val Gly Ala 100 105 110 Gly Gly Val Glu Asn Ala Val Ala Tyr Ala Leu Val Thr His Gly Val 115 120 125 Gln Lys Leu Gln Val Ala Asp Leu Asp Thr Ser Arg Ala Gln Ala Leu 130 135 140 Ala Asp Val Ile Asn Asn Ala Val Gly Arg Glu Ala Val Val Gly Val 145 150 155 160 Asp Ala Arg Gly Ile Glu Asp Val Ile Ala Ala Ala Asp Gly Val Val 165 170 175 Asn Ala Thr Pro Met Gly Met Pro Ala His Pro Gly Thr Ala Phe Asp 180 185 190 Val Ser Cys Leu Thr Lys Asp His Trp Val Gly Asp Val Val Tyr Met 195 200 205 Pro Ile Glu Thr Glu Leu Leu Lys Ala Ala Arg Ala Leu Gly Cys Glu 210 215 220 Thr Leu Asp Gly Thr Arg Met Ala Ile His Gln Ala Val Asp Ala Phe 225 230 235 240 Arg Leu Phe Thr Gly Leu Glu Pro Asp Val Ser Arg Met Arg Glu Thr 245 250 255 Phe Leu Ser Leu 260 <210> 437 <211> 927 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(904) <223> RXA02093 <400> 437 ggcaggaatt tcccgaaaac ttccaccaat aatcaagcca tatcccacac aatcaggcat 60 ttgctcttcc tttgctccgc atgagtataa aatcactgtc atg gtc aac tac gtc 115 Met Val Asn Tyr Val 1 5 gac agg gaa aca acc ctg tgc atc tct ctc gct gct cgt cca tcc aac 163 Asp Arg Glu Thr Thr Leu Cys Ile Ser Leu Ala Ala Arg Pro Ser Asn 10 15 20 cat ggt gtt cgt ttc cac aac tgg ctt tac gct gaa ctt gga ttg aac 211 His Gly Val Arg Phe His Asn Trp Leu Tyr Ala Glu Leu Gly Leu Asn 25 30 35 tac ctg tac aag gct gtt gcc cca gca gat atc acc gct gca gtc gca 259 Tyr Leu Tyr Lys Ala Val Ala Pro Ala Asp Ile Thr Ala Ala Val Ala 40 45 50 ggt atc cgt ggt ctg aac att cgc ggc gca ggt gtc tcc atg cca tac 307 Gly Ile Arg Gly Leu Asn Ile Arg Gly Ala Gly Val Ser Met Pro Tyr 55 60 65 aag agc gat gtc atc cca ctc atc gat gag ttg cat cct tcc gca gag 355 Lys Ser Asp Val Ile Pro Leu Ile Asp Glu Leu His Pro Ser Ala Glu 70 75 80 85 cgc ata cgt tct gtt aac acc atc gtc aac aat gac gga cac ctt gtc 403 Arg Ile Arg Ser Val Asn Thr Ile Val Asn Asn Asp Gly His Leu Val 90 95 100 gga tac aac acc gac tac act gcg gtg tac cac ctc ctt gaa gaa cac 451 Gly Tyr Asn Thr Asp Tyr Thr Ala Val Tyr His Leu Leu Glu Glu His 105 110 115 cgc gtg aac ccc aat gca cga gta gct atc aag gga tcc ggc ggc atg 499 Arg Val Asn Pro Asn Ala Arg Val Ala Ile Lys Gly Ser Gly Gly Met 120 125 130 gcc aat gct gtt gtt gca gct ctt gct gag tat ggt ctg agt ggc acc 547 Ala Asn Ala Val Val Ala Ala Leu Ala Glu Tyr Gly Leu Ser Gly Thr 135 140 145 gtc gtt gcc cgc aac cac acc acc ggt tct gcg cta gct tcc cgt tac 595 Val Val Ala Arg Asn His Thr Thr Gly Ser Ala Leu Ala Ser Arg Tyr 150 155 160 165 ggt tgg gaa tac tcc gca act gtt ccg gaa gac gca aaa att ttg gtt 643 Gly Trp Glu Tyr Ser Ala Thr Val Pro Glu Asp Ala Lys Ile Leu Val 170 175 180 aat gta acc cca atg gga atg aat gga cct gac caa gac gtt gta tct 691 Asn Val Thr Pro Met Gly Met Asn Gly Pro Asp Gln Asp Val Val Ser 185 190 195 ttt ggt gag gat gaa gta gac cga gcc gac gta atc ttt gac tgc gta 739 Phe Gly Glu Asp Glu Val Asp Arg Ala Asp Val Ile Phe Asp Cys Val 200 205 210 gca ttc ccc gtc gag acc cca ctg att aag ttg gcc aag gaa aag ggt 787 Ala Phe Pro Val Glu Thr Pro Leu Ile Lys Leu Ala Lys Glu Lys Gly 215 220 225 aag caa acc atc gac ggc gga gaa gtt gcc gct ctt cag gca gca gag 835 Lys Gln Thr Ile Asp Gly Gly Glu Val Ala Ala Leu Gln Ala Ala Glu 230 235 240 245 cag ttc cac ctc tac acc gga gtt ctt cca acc aac gac cag atc att 883 Gln Phe His Leu Tyr Thr Gly Val Leu Pro Thr Asn Asp Gln Ile Ile 250 255 260 gct gcg gag gag ttc tcc aag taaatttctc tcccctattt tta 927 Ala Ala Glu Glu Phe Ser Lys 265 <210> 438 <211> 268 <212> PRT <213> Corynebacterium glutamicum <400> 438 Met Val Asn Tyr Val Asp Arg Glu Thr Thr Leu Cys Ile Ser Leu Ala 1 5 10 15 Ala Arg Pro Ser Asn His Gly Val Arg Phe His Asn Trp Leu Tyr Ala 20 25 30 Glu Leu Gly Leu Asn Tyr Leu Tyr Lys Ala Val Ala Pro Ala Asp Ile 35 40 45 Thr Ala Ala Val Ala Gly Ile Arg Gly Leu Asn Ile Arg Gly Ala Gly 50 55 60 Val Ser Met Pro Tyr Lys Ser Asp Val Ile Pro Leu Ile Asp Glu Leu 65 70 75 80 His Pro Ser Ala Glu Arg Ile Arg Ser Val Asn Thr Ile Val Asn Asn 85 90 95 Asp Gly His Leu Val Gly Tyr Asn Thr Asp Tyr Thr Ala Val Tyr His 100 105 110 Leu Leu Glu Glu His Arg Val Asn Pro Asn Ala Arg Val Ala Ile Lys 115 120 125 Gly Ser Gly Gly Met Ala Asn Ala Val Val Ala Ala Leu Ala Glu Tyr 130 135 140 Gly Leu Ser Gly Thr Val Val Ala Arg Asn His Thr Thr Gly Ser Ala 145 150 155 160 Leu Ala Ser Arg Tyr Gly Trp Glu Tyr Ser Ala Thr Val Pro Glu Asp 165 170 175 Ala Lys Ile Leu Val Asn Val Thr Pro Met Gly Met Asn Gly Pro Asp 180 185 190 Gln Asp Val Val Ser Phe Gly Glu Asp Glu Val Asp Arg Ala Asp Val 195 200 205 Ile Phe Asp Cys Val Ala Phe Pro Val Glu Thr Pro Leu Ile Lys Leu 210 215 220 Ala Lys Glu Lys Gly Lys Gln Thr Ile Asp Gly Gly Glu Val Ala Ala 225 230 235 240 Leu Gln Ala Ala Glu Gln Phe His Leu Tyr Thr Gly Val Leu Pro Thr 245 250 255 Asn Asp Gln Ile Ile Ala Ala Glu Glu Phe Ser Lys 260 265 <210> 439 <211> 951 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(928) <223> RXA02791 <400> 439 accgtgttca acgacacctt cgaagagcac gaagccgaca ttgagcaagc tttgaacagt 60 ggcgttctag acagcaaccg ataaggatca gcgaataaaa ttg ggt tct cac atc 115 Leu Gly Ser His Ile 1 5 act cac cgg gcg gcc gta ctc ggc tca ccc atc gag cat tcc aaa tcc 163 Thr His Arg Ala Ala Val Leu Gly Ser Pro Ile Glu His Ser Lys Ser 10 15 20 cca gtc ctc cac aac acc ggc tat aaa gcc ctc gga ctg gac caa tgg 211 Pro Val Leu His Asn Thr Gly Tyr Lys Ala Leu Gly Leu Asp Gln Trp 25 30 35 gaa tac gac cgc ttt gag tgc acc ggc gac atg ctc ccc ggc atc gtc 259 Glu Tyr Asp Arg Phe Glu Cys Thr Gly Asp Met Leu Pro Gly Ile Val 40 45 50 tcc ggc gct gat gaa acc tac tgc gga ttc tcc gtc acc atg ccg tct 307 Ser Gly Ala Asp Glu Thr Tyr Cys Gly Phe Ser Val Thr Met Pro Ser 55 60 65 aaa ttc gca gct ctt gaa ttc gcc gac gaa gta acc gaa cgc gcc tgc 355 Lys Phe Ala Ala Leu Glu Phe Ala Asp Glu Val Thr Glu Arg Ala Cys 70 75 80 85 gcc atc ggc tcc gca aac acc ttg ctg cgc acg gcc acc gga tgg cgc 403 Ala Ile Gly Ser Ala Asn Thr Leu Leu Arg Thr Ala Thr Gly Trp Arg 90 95 100 gcc gac aac acc gac gtc gac ggc atc agg gga gct ctc ggt gaa ctc 451 Ala Asp Asn Thr Asp Val Asp Gly Ile Arg Gly Ala Leu Gly Glu Leu 105 110 115 ctc ggc ggc gca tca ctg gcc ggc aaa cac gcc atc gtc atc ggc tcc 499 Leu Gly Gly Ala Ser Leu Ala Gly Lys His Ala Ile Val Ile Gly Ser 120 125 130 ggc ggc acc gca cgc ccc gcc atc tgg gca ctc atc gaa gcc ggg gtc 547 Gly Gly Thr Ala Arg Pro Ala Ile Trp Ala Leu Ile Glu Ala Gly Val 135 140 145 gcc cgg atc acg gtg ctc aac cgc tcc gat cgc acc gcc gaa ctg caa 595 Ala Arg Ile Thr Val Leu Asn Arg Ser Asp Arg Thr Ala Glu Leu Gln 150 155 160 165 acg ctt ttc gac gaa acc ccc acc acc ttg gcc tac gcc ccg ctc gag 643 Thr Leu Phe Asp Glu Thr Pro Thr Thr Leu Ala Tyr Ala Pro Leu Glu 170 175 180 cat ctc cac atc gaa gcc gac gtc gta gtc tct aca gtg ccc tcc gca 691 His Leu His Ile Glu Ala Asp Val Val Val Ser Thr Val Pro Ser Ala 185 190 195 gca atc gca ggc ctc gaa gac acc ctt gcg atc gcc cca gtc ctc gac 739 Ala Ile Ala Gly Leu Glu Asp Thr Leu Ala Ile Ala Pro Val Leu Asp 200 205 210 gtc atc tac gac ccc tgg cca aca cca ctc gta gaa gtc aca cga gcc 787 Val Ile Tyr Asp Pro Trp Pro Thr Pro Leu Val Glu Val Thr Arg Ala 215 220 225 aaa ggc ctc aaa gct gtc gga ggc cac gtc atg ctg gca cac cag tcc 835 Lys Gly Leu Lys Ala Val Gly Gly His Val Met Leu Ala His Gln Ser 230 235 240 245 tac gga cag ttt gaa caa ttc acc gga atg gat gca ccc cgc gat gcc 883 Tyr Gly Gln Phe Glu Gln Phe Thr Gly Met Asp Ala Pro Arg Asp Ala 250 255 260 atg cgt gag gct ttg gaa gag tct tta ggc atc tca gaa gaa cac 928 Met Arg Glu Ala Leu Glu Glu Ser Leu Gly Ile Ser Glu Glu His 265 270 275 taagtccccg ccacctcctc aac 951 <210> 440 <211> 276 <212> PRT <213> Corynebacterium glutamicum <400> 440 Leu Gly Ser His Ile Thr His Arg Ala Ala Val Leu Gly Ser Pro Ile 1 5 10 15 Glu His Ser Lys Ser Pro Val Leu His Asn Thr Gly Tyr Lys Ala Leu 20 25 30 Gly Leu Asp Gln Trp Glu Tyr Asp Arg Phe Glu Cys Thr Gly Asp Met 35 40 45 Leu Pro Gly Ile Val Ser Gly Ala Asp Glu Thr Tyr Cys Gly Phe Ser 50 55 60 Val Thr Met Pro Ser Lys Phe Ala Ala Leu Glu Phe Ala Asp Glu Val 65 70 75 80 Thr Glu Arg Ala Cys Ala Ile Gly Ser Ala Asn Thr Leu Leu Arg Thr 85 90 95 Ala Thr Gly Trp Arg Ala Asp Asn Thr Asp Val Asp Gly Ile Arg Gly 100 105 110 Ala Leu Gly Glu Leu Leu Gly Gly Ala Ser Leu Ala Gly Lys His Ala 115 120 125 Ile Val Ile Gly Ser Gly Gly Thr Ala Arg Pro Ala Ile Trp Ala Leu 130 135 140 Ile Glu Ala Gly Val Ala Arg Ile Thr Val Leu Asn Arg Ser Asp Arg 145 150 155 160 Thr Ala Glu Leu Gln Thr Leu Phe Asp Glu Thr Pro Thr Thr Leu Ala 165 170 175 Tyr Ala Pro Leu Glu His Leu His Ile Glu Ala Asp Val Val Val Ser 180 185 190 Thr Val Pro Ser Ala Ala Ile Ala Gly Leu Glu Asp Thr Leu Ala Ile 195 200 205 Ala Pro Val Leu Asp Val Ile Tyr Asp Pro Trp Pro Thr Pro Leu Val 210 215 220 Glu Val Thr Arg Ala Lys Gly Leu Lys Ala Val Gly Gly His Val Met 225 230 235 240 Leu Ala His Gln Ser Tyr Gly Gln Phe Glu Gln Phe Thr Gly Met Asp 245 250 255 Ala Pro Arg Asp Ala Met Arg Glu Ala Leu Glu Glu Ser Leu Gly Ile 260 265 270 Ser Glu Glu His 275 <210> 441 <211> 693 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(670) <223> RXA01699 <400> 441 ctgcagaaat tcggcggtga ctccctgagc gaaaccaaga gcaacattga cacctacctc 60 aaaaacattg aggaacgaat gaaattcgaa ggtttagagg atg gag cgt aat gaa 115 Met Glu Arg Asn Glu 1 5 gtg aat gat caa att cac tta gat cat caa tca gat gac acc tct gaa 163 Val Asn Asp Gln Ile His Leu Asp His Gln Ser Asp Asp Thr Ser Glu 10 15 20 tgc tcc tgc ccg atc gtg gtt ctt gtg ggt ttg cca gga gct gga aaa 211 Cys Ser Cys Pro Ile Val Val Leu Val Gly Leu Pro Gly Ala Gly Lys 25 30 35 tcc acc att gga cgt cga tta gcg cgc gcc tta aac act gaa ctc gtc 259 Ser Thr Ile Gly Arg Arg Leu Ala Arg Ala Leu Asn Thr Glu Leu Val 40 45 50 gac tcc gac gaa ctg att gag cgc gcc acc gga aaa gcc tgt ggc gcc 307 Asp Ser Asp Glu Leu Ile Glu Arg Ala Thr Gly Lys Ala Cys Gly Ala 55 60 65 gtg ttc agc gag ctc ggc gag cca gcc ttc cgc gag ctc gag gcc atc 355 Val Phe Ser Glu Leu Gly Glu Pro Ala Phe Arg Glu Leu Glu Ala Ile 70 75 80 85 cac gtg gcc gaa gca ctg aaa tcc tcc gga gtg gtg agc ttg gga ggc 403 His Val Ala Glu Ala Leu Lys Ser Ser Gly Val Val Ser Leu Gly Gly 90 95 100 gga tct gtg ctg aca gaa tcc acc cgt gaa ctg ctc aaa ggc cag gac 451 Gly Ser Val Leu Thr Glu Ser Thr Arg Glu Leu Leu Lys Gly Gln Asp 105 110 115 gtg gtc tgg atc gac gtg cca gta gaa gaa ggc atc agg cgc acc gca 499 Val Val Trp Ile Asp Val Pro Val Glu Glu Gly Ile Arg Arg Thr Ala 120 125 130 aac gag cgt tcc cgc ccc gtg ctg caa gcc gcc gac ccc gcc gag cac 547 Asn Glu Arg Ser Arg Pro Val Leu Gln Ala Ala Asp Pro Ala Glu His 135 140 145 tac cgc aac ctg gtg aaa gtg cgc acc ccg ttg tac gaa gag gtg gca 595 Tyr Arg Asn Leu Val Lys Val Arg Thr Pro Leu Tyr Glu Glu Val Ala 150 155 160 165 acc tac cga ctt cgc acc aac aac cgc agc ccc cag caa gtg gtg gca 643 Thr Tyr Arg Leu Arg Thr Asn Asn Arg Ser Pro Gln Gln Val Val Ala 170 175 180 gca gtg ttg cat cat cta gaa atc gat taattaaacc gggcacctga 690 Ala Val Leu His His Leu Glu Ile Asp 185 190 tta 693 <210> 442 <211> 190 <212> PRT <213> Corynebacterium glutamicum <400> 442 Met Glu Arg Asn Glu Val Asn Asp Gln Ile His Leu Asp His Gln Ser 1 5 10 15 Asp Asp Thr Ser Glu Cys Ser Cys Pro Ile Val Val Leu Val Gly Leu 20 25 30 Pro Gly Ala Gly Lys Ser Thr Ile Gly Arg Arg Leu Ala Arg Ala Leu 35 40 45 Asn Thr Glu Leu Val Asp Ser Asp Glu Leu Ile Glu Arg Ala Thr Gly 50 55 60 Lys Ala Cys Gly Ala Val Phe Ser Glu Leu Gly Glu Pro Ala Phe Arg 65 70 75 80 Glu Leu Glu Ala Ile His Val Ala Glu Ala Leu Lys Ser Ser Gly Val 85 90 95 Val Ser Leu Gly Gly Gly Ser Val Leu Thr Glu Ser Thr Arg Glu Leu 100 105 110 Leu Lys Gly Gln Asp Val Val Trp Ile Asp Val Pro Val Glu Glu Gly 115 120 125 Ile Arg Arg Thr Ala Asn Glu Arg Ser Arg Pro Val Leu Gln Ala Ala 130 135 140 Asp Pro Ala Glu His Tyr Arg Asn Leu Val Lys Val Arg Thr Pro Leu 145 150 155 160 Tyr Glu Glu Val Ala Thr Tyr Arg Leu Arg Thr Asn Asn Arg Ser Pro 165 170 175 Gln Gln Val Val Ala Ala Val Leu His His Leu Glu Ile Asp 180 185 190 <210> 443 <211> 959 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (97)..(936) <223> RXA00952 <400> 443 catcctcgtc tccctatccg gccgtggcga caaggacgtt gaccacgtgc gccgcaccct 60 cgaagaaaat ccagaactga tcctgaagga caaccg atg agc cgt tac gac gat 114 Met Ser Arg Tyr Asp Asp 1 5 ctt ttt gca cgc ctc gac acg gca ggg gag ggc gcc ttt gtt ccc ttc 162 Leu Phe Ala Arg Leu Asp Thr Ala Gly Glu Gly Ala Phe Val Pro Phe 10 15 20 atc atg ctg agc gac cct tca cca gag gag gct ttc cag atc atc tcc 210 Ile Met Leu Ser Asp Pro Ser Pro Glu Glu Ala Phe Gln Ile Ile Ser 25 30 35 aca gca atc gaa gct ggc gca gat gca ctg gaa ctt ggc gta cct ttc 258 Thr Ala Ile Glu Ala Gly Ala Asp Ala Leu Glu Leu Gly Val Pro Phe 40 45 50 tcc gac cca gtt gcc gat ggc ccc acc gtc gcg gaa tcc cac ctc cgc 306 Ser Asp Pro Val Ala Asp Gly Pro Thr Val Ala Glu Ser His Leu Arg 55 60 65 70 gca ctc gac ggc ggc gcc acc gta gac agc gca ctc gag cag atc aag 354 Ala Leu Asp Gly Gly Ala Thr Val Asp Ser Ala Leu Glu Gln Ile Lys 75 80 85 cgc gtg cgc gca gcc tac cca gag gtt ccc atc gga atg ctc atc tac 402 Arg Val Arg Ala Ala Tyr Pro Glu Val Pro Ile Gly Met Leu Ile Tyr 90 95 100 ggc aac gtt cct ttc acc cgt ggc ttg gat cgc ttc tac caa gag ttc 450 Gly Asn Val Pro Phe Thr Arg Gly Leu Asp Arg Phe Tyr Gln Glu Phe 105 110 115 gct gaa gct ggc gca gac tcc atc ctc ctg cca gac gtc cca gtc cga 498 Ala Glu Ala Gly Ala Asp Ser Ile Leu Leu Pro Asp Val Pro Val Arg 120 125 130 gaa ggc gca ccg ttt tct gca gca gct gca gca gcc gga att gat ccc 546 Glu Gly Ala Pro Phe Ser Ala Ala Ala Ala Ala Ala Gly Ile Asp Pro 135 140 145 150 att tac atc gct ccg gcc aac gcc agc gag aaa acc ctc gag ggt gtc 594 Ile Tyr Ile Ala Pro Ala Asn Ala Ser Glu Lys Thr Leu Glu Gly Val 155 160 165 tcc gcc gca tca aag ggc tac atc tac gcc atc tcc cgc gac ggc gtc 642 Ser Ala Ala Ser Lys Gly Tyr Ile Tyr Ala Ile Ser Arg Asp Gly Val 170 175 180 acc ggc acc gaa cgt gaa tca tcc acc gac ggc ctg tcc gca gtg gtg 690 Thr Gly Thr Glu Arg Glu Ser Ser Thr Asp Gly Leu Ser Ala Val Val 185 190 195 gac aac atc aag aaa ttt gat ggc gca ccc atc ctc ttg ggc ttc ggc 738 Asp Asn Ile Lys Lys Phe Asp Gly Ala Pro Ile Leu Leu Gly Phe Gly 200 205 210 atc tca tcc cct cag cac gtg gca gac gcg att gca gcg ggt gct tcc 786 Ile Ser Ser Pro Gln His Val Ala Asp Ala Ile Ala Ala Gly Ala Ser 215 220 225 230 ggt gcg atc acg ggt tcc gcg atc acc aag atc att gct tcc cac tgc 834 Gly Ala Ile Thr Gly Ser Ala Ile Thr Lys Ile Ile Ala Ser His Cys 235 240 245 gaa ggt gag cac ccg aac ccg tcc acc att cga gat atg gac ggt ttg 882 Glu Gly Glu His Pro Asn Pro Ser Thr Ile Arg Asp Met Asp Gly Leu 250 255 260 aag aag gat ctc act gag ttc atc tct gcg atg aag gca gcg acc aag 930 Lys Lys Asp Leu Thr Glu Phe Ile Ser Ala Met Lys Ala Ala Thr Lys 265 270 275 aag gtt taggccttta aatgtggcaa tgt 959 Lys Val 280 <210> 444 <211> 280 <212> PRT <213> Corynebacterium glutamicum <400> 444 Met Ser Arg Tyr Asp Asp Leu Phe Ala Arg Leu Asp Thr Ala Gly Glu 1 5 10 15 Gly Ala Phe Val Pro Phe Ile Met Leu Ser Asp Pro Ser Pro Glu Glu 20 25 30 Ala Phe Gln Ile Ile Ser Thr Ala Ile Glu Ala Gly Ala Asp Ala Leu 35 40 45 Glu Leu Gly Val Pro Phe Ser Asp Pro Val Ala Asp Gly Pro Thr Val 50 55 60 Ala Glu Ser His Leu Arg Ala Leu Asp Gly Gly Ala Thr Val Asp Ser 65 70 75 80 Ala Leu Glu Gln Ile Lys Arg Val Arg Ala Ala Tyr Pro Glu Val Pro 85 90 95 Ile Gly Met Leu Ile Tyr Gly Asn Val Pro Phe Thr Arg Gly Leu Asp 100 105 110 Arg Phe Tyr Gln Glu Phe Ala Glu Ala Gly Ala Asp Ser Ile Leu Leu 115 120 125 Pro Asp Val Pro Val Arg Glu Gly Ala Pro Phe Ser Ala Ala Ala Ala 130 135 140 Ala Ala Gly Ile Asp Pro Ile Tyr Ile Ala Pro Ala Asn Ala Ser Glu 145 150 155 160 Lys Thr Leu Glu Gly Val Ser Ala Ala Ser Lys Gly Tyr Ile Tyr Ala 165 170 175 Ile Ser Arg Asp Gly Val Thr Gly Thr Glu Arg Glu Ser Ser Thr Asp 180 185 190 Gly Leu Ser Ala Val Val Asp Asn Ile Lys Lys Phe Asp Gly Ala Pro 195 200 205 Ile Leu Leu Gly Phe Gly Ile Ser Ser Pro Gln His Val Ala Asp Ala 210 215 220 Ile Ala Ala Gly Ala Ser Gly Ala Ile Thr Gly Ser Ala Ile Thr Lys 225 230 235 240 Ile Ile Ala Ser His Cys Glu Gly Glu His Pro Asn Pro Ser Thr Ile 245 250 255 Arg Asp Met Asp Gly Leu Lys Lys Asp Leu Thr Glu Phe Ile Ser Ala 260 265 270 Met Lys Ala Ala Thr Lys Lys Val 275 280 <210> 445 <211> 1237 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1237) <223> RXN00956 <400> 445 gccggtgcag gcacgtgggc tggggcgaaa gacgccggcg cgctgctgaa aattttagcg 60 accatctcca cattccatta ctaaaggttt aaataggatc atg act gaa aaa gaa 115 Met Thr Glu Lys Glu 1 5 aac ttg ggc ggc tcc acg ctg ctg cct gca tac ttc ggt gaa ttc ggc 163 Asn Leu Gly Gly Ser Thr Leu Leu Pro Ala Tyr Phe Gly Glu Phe Gly 10 15 20 ggc cag ttc gtc gcg gaa tcc ctc ctg cct gct ctc gac cag ctg gag 211 Gly Gln Phe Val Ala Glu Ser Leu Leu Pro Ala Leu Asp Gln Leu Glu 25 30 35 aag gcc ttc gtt gac gcg acc aac agc cca gag ttc cgc gaa gaa ctc 259 Lys Ala Phe Val Asp Ala Thr Asn Ser Pro Glu Phe Arg Glu Glu Leu 40 45 50 ggc ggc tac ctc cgc gat tac ctc ggc cgc cca acc ccg ctg acc gaa 307 Gly Gly Tyr Leu Arg Asp Tyr Leu Gly Arg Pro Thr Pro Leu Thr Glu 55 60 65 tgc tcc aac ctg cca ctc gca ggc gaa ggc aaa ggc ttt gcg cgg atc 355 Cys Ser Asn Leu Pro Leu Ala Gly Glu Gly Lys Gly Phe Ala Arg Ile 70 75 80 85 ttc ctc aag cgc gaa gac ctc gtc cac ggc ggt gca cac aaa act aac 403 Phe Leu Lys Arg Glu Asp Leu Val His Gly Gly Ala His Lys Thr Asn 90 95 100 cag gtg atc ggc cag gtg ctg ctt gcc aag cgc atg ggc aaa acc cgc 451 Gln Val Ile Gly Gln Val Leu Leu Ala Lys Arg Met Gly Lys Thr Arg 105 110 115 atc atc gca gag acc ggc gca ggc cag cac ggc acc gcc acc gct ctc 499 Ile Ile Ala Glu Thr Gly Ala Gly Gln His Gly Thr Ala Thr Ala Leu 120 125 130 gca tgt gcg ctc atg ggc ctc gag tgc gtt gtc tac atg ggc gcc aag 547 Ala Cys Ala Leu Met Gly Leu Glu Cys Val Val Tyr Met Gly Ala Lys 135 140 145 gac gtt gcc cgc cag cag ccc aac gtc tac cgc atg cag ctg cac ggc 595 Asp Val Ala Arg Gln Gln Pro Asn Val Tyr Arg Met Gln Leu His Gly 150 155 160 165 gcg aag gtc atc ccc gtg gaa tct ggt tcc ggc acc ctg aag gac gcc 643 Ala Lys Val Ile Pro Val Glu Ser Gly Ser Gly Thr Leu Lys Asp Ala 170 175 180 gtg aat gaa gcg ctg cgc gat tgg acc gca acc ttc cac gag tcc cac 691 Val Asn Glu Ala Leu Arg Asp Trp Thr Ala Thr Phe His Glu Ser His 185 190 195 tac ctt ctc ggc acc ccc gcc ggc ccg cac cca ttc cca acc atc gtg 739 Tyr Leu Leu Gly Thr Pro Ala Gly Pro His Pro Phe Pro Thr Ile Val 200 205 210 cgt gaa ttc cac aag gtg atc tct gag gaa gcc aag gca cag atg cta 787 Arg Glu Phe His Lys Val Ile Ser Glu Glu Ala Lys Ala Gln Met Leu 215 220 225 gag cgc acc ggc aag ctt ccc gac gtt gtg gtc gcc tgt gtc ggt ggt 835 Glu Arg Thr Gly Lys Leu Pro Asp Val Val Val Ala Cys Val Gly Gly 230 235 240 245 ggc tcc aac gcc atc ggc atg ttc gca gac ttc att gac gat gaa ggt 883 Gly Ser Asn Ala Ile Gly Met Phe Ala Asp Phe Ile Asp Asp Glu Gly 250 255 260 gta gag ctc gtc ggc gct gag cca gcc ggt gaa ggc ctc gac tcc ggc 931 Val Glu Leu Val Gly Ala Glu Pro Ala Gly Glu Gly Leu Asp Ser Gly 265 270 275 aag cac ggc gca acc atc acc aac ggt cag atc ggc atc ctg cac ggc 979 Lys His Gly Ala Thr Ile Thr Asn Gly Gln Ile Gly Ile Leu His Gly 280 285 290 acc cgt tcc tac ctg atg cgc aac tcc gac ggc caa gtg gaa gag tcc 1027 Thr Arg Ser Tyr Leu Met Arg Asn Ser Asp Gly Gln Val Glu Glu Ser 295 300 305 tac tcc atc tcc gcc gga ctt gat tac cca ggc gtc ggc cca cag cac 1075 Tyr Ser Ile Ser Ala Gly Leu Asp Tyr Pro Gly Val Gly Pro Gln His 310 315 320 325 gca cac ctg cac gcc acc ggc cgc gcc acc tac gtt ggt atc acc gac 1123 Ala His Leu His Ala Thr Gly Arg Ala Thr Tyr Val Gly Ile Thr Asp 330 335 340 gcc gaa gcc ctc caa gca ttc cag tac ctc gcc cgc tac gaa ggc atc 1171 Ala Glu Ala Leu Gln Ala Phe Gln Tyr Leu Ala Arg Tyr Glu Gly Ile 345 350 355 atc ccc gca ctg gaa tcc tca cac gcg ttc gcc tac gca ctc aag cgc 1219 Ile Pro Ala Leu Glu Ser Ser His Ala Phe Ala Tyr Ala Leu Lys Arg 360 365 370 gcc aag acc gcc gaa gta 1237 Ala Lys Thr Ala Glu Val 375 <210> 446 <211> 379 <212> PRT <213> Corynebacterium glutamicum <400> 446 Met Thr Glu Lys Glu Asn Leu Gly Gly Ser Thr Leu Leu Pro Ala Tyr 1 5 10 15 Phe Gly Glu Phe Gly Gly Gln Phe Val Ala Glu Ser Leu Leu Pro Ala 20 25 30 Leu Asp Gln Leu Glu Lys Ala Phe Val Asp Ala Thr Asn Ser Pro Glu 35 40 45 Phe Arg Glu Glu Leu Gly Gly Tyr Leu Arg Asp Tyr Leu Gly Arg Pro 50 55 60 Thr Pro Leu Thr Glu Cys Ser Asn Leu Pro Leu Ala Gly Glu Gly Lys 65 70 75 80 Gly Phe Ala Arg Ile Phe Leu Lys Arg Glu Asp Leu Val His Gly Gly 85 90 95 Ala His Lys Thr Asn Gln Val Ile Gly Gln Val Leu Leu Ala Lys Arg 100 105 110 Met Gly Lys Thr Arg Ile Ile Ala Glu Thr Gly Ala Gly Gln His Gly 115 120 125 Thr Ala Thr Ala Leu Ala Cys Ala Leu Met Gly Leu Glu Cys Val Val 130 135 140 Tyr Met Gly Ala Lys Asp Val Ala Arg Gln Gln Pro Asn Val Tyr Arg 145 150 155 160 Met Gln Leu His Gly Ala Lys Val Ile Pro Val Glu Ser Gly Ser Gly 165 170 175 Thr Leu Lys Asp Ala Val Asn Glu Ala Leu Arg Asp Trp Thr Ala Thr 180 185 190 Phe His Glu Ser His Tyr Leu Leu Gly Thr Pro Ala Gly Pro His Pro 195 200 205 Phe Pro Thr Ile Val Arg Glu Phe His Lys Val Ile Ser Glu Glu Ala 210 215 220 Lys Ala Gln Met Leu Glu Arg Thr Gly Lys Leu Pro Asp Val Val Val 225 230 235 240 Ala Cys Val Gly Gly Gly Ser Asn Ala Ile Gly Met Phe Ala Asp Phe 245 250 255 Ile Asp Asp Glu Gly Val Glu Leu Val Gly Ala Glu Pro Ala Gly Glu 260 265 270 Gly Leu Asp Ser Gly Lys His Gly Ala Thr Ile Thr Asn Gly Gln Ile 275 280 285 Gly Ile Leu His Gly Thr Arg Ser Tyr Leu Met Arg Asn Ser Asp Gly 290 295 300 Gln Val Glu Glu Ser Tyr Ser Ile Ser Ala Gly Leu Asp Tyr Pro Gly 305 310 315 320 Val Gly Pro Gln His Ala His Leu His Ala Thr Gly Arg Ala Thr Tyr 325 330 335 Val Gly Ile Thr Asp Ala Glu Ala Leu Gln Ala Phe Gln Tyr Leu Ala 340 345 350 Arg Tyr Glu Gly Ile Ile Pro Ala Leu Glu Ser Ser His Ala Phe Ala 355 360 365 Tyr Ala Leu Lys Arg Ala Lys Thr Ala Glu Val 370 375 <210> 447 <211> 1231 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1231) <223> FRXA00956 <400> 447 gccggtgcag gcacgtgggc tggggcgaaa gacgccggcg cgctgctgaa aattttagcg 60 accatctcca cattccatta ctaaaggttt aaataggatc atg act gaa aaa gaa 115 Met Thr Glu Lys Glu 1 5 aac ttg ggc ggc tcc acg ctg ctg cct gca tac ttc ggt gaa ttc ggc 163 Asn Leu Gly Gly Ser Thr Leu Leu Pro Ala Tyr Phe Gly Glu Phe Gly 10 15 20 ggc cag ttc gtc gcg gaa tcc ctc ctg cct gct ctc gac cag ctg gag 211 Gly Gln Phe Val Ala Glu Ser Leu Leu Pro Ala Leu Asp Gln Leu Glu 25 30 35 aag gcc ttc gtt gac gcg acc aac agc cca gag ttc cgc gaa gaa ctc 259 Lys Ala Phe Val Asp Ala Thr Asn Ser Pro Glu Phe Arg Glu Glu Leu 40 45 50 ggc ggc tac ctc cgc gat tac ctc ggc cgc cca acc ccg ctg acc gaa 307 Gly Gly Tyr Leu Arg Asp Tyr Leu Gly Arg Pro Thr Pro Leu Thr Glu 55 60 65 tgc tcc aac ctg cca ctc gca ggc gaa ggc aaa ggc ttt gcg cgg atc 355 Cys Ser Asn Leu Pro Leu Ala Gly Glu Gly Lys Gly Phe Ala Arg Ile 70 75 80 85 ttc ctc aag cgc gaa gac ctc gtc cac ggc ggt gca cac aaa act aac 403 Phe Leu Lys Arg Glu Asp Leu Val His Gly Gly Ala His Lys Thr Asn 90 95 100 cag gtg atc ggc cag gtg ctg ctt gcc aag cgc atg ggc aaa acc cgc 451 Gln Val Ile Gly Gln Val Leu Leu Ala Lys Arg Met Gly Lys Thr Arg 105 110 115 atc atc gca gag acc ggc gca ggc cag cac ggc acc gcc acc gct ctc 499 Ile Ile Ala Glu Thr Gly Ala Gly Gln His Gly Thr Ala Thr Ala Leu 120 125 130 gca tgt gcg ctc atg ggc ctc gag tgc gtt gtc tac atg ggc gcc aag 547 Ala Cys Ala Leu Met Gly Leu Glu Cys Val Val Tyr Met Gly Ala Lys 135 140 145 gac gtt gcc cgc cag cag ccc aac gtc tac cgc atg cag ctg cac ggc 595 Asp Val Ala Arg Gln Gln Pro Asn Val Tyr Arg Met Gln Leu His Gly 150 155 160 165 gcg aag gtc atc ccc gtg gaa tct ggt tcc ggc acc ctg aag gac gcc 643 Ala Lys Val Ile Pro Val Glu Ser Gly Ser Gly Thr Leu Lys Asp Ala 170 175 180 gtg aat gaa gcg ctg cgc gat tgg acc gca acc ttc cac gag tcc cac 691 Val Asn Glu Ala Leu Arg Asp Trp Thr Ala Thr Phe His Glu Ser His 185 190 195 tac ctt ctc ggc acc ccc gcc ggc ccg cac cca ttc cca acc atc gtg 739 Tyr Leu Leu Gly Thr Pro Ala Gly Pro His Pro Phe Pro Thr Ile Val 200 205 210 cgt gaa ttc cac aag gtg atc tct gag gaa gcc aag gca cag atg cta 787 Arg Glu Phe His Lys Val Ile Ser Glu Glu Ala Lys Ala Gln Met Leu 215 220 225 gag cgc acc ggc aag ctt ccc gac gtt gtg gtc gcc tgt gtc ggt ggt 835 Glu Arg Thr Gly Lys Leu Pro Asp Val Val Val Ala Cys Val Gly Gly 230 235 240 245 ggc tcc aac gcc atc ggc atg ttc gca gac ttc att gac gat gaa ggt 883 Gly Ser Asn Ala Ile Gly Met Phe Ala Asp Phe Ile Asp Asp Glu Gly 250 255 260 gta gag ctc gtc ggc gct gag cca gcc ggt gaa ggc ctc gac tcc ggc 931 Val Glu Leu Val Gly Ala Glu Pro Ala Gly Glu Gly Leu Asp Ser Gly 265 270 275 aag cac ggc gca acc atc acc aac ggt cag atc ggc atc ctg cac ggc 979 Lys His Gly Ala Thr Ile Thr Asn Gly Gln Ile Gly Ile Leu His Gly 280 285 290 acc cgt tcc tac ctg atg cgc aac tcc gac ggc caa gtg gaa gag tcc 1027 Thr Arg Ser Tyr Leu Met Arg Asn Ser Asp Gly Gln Val Glu Glu Ser 295 300 305 tac tcc atc tcc gcc gga ctt gat tac cca ggc gtc ggc cca cag cac 1075 Tyr Ser Ile Ser Ala Gly Leu Asp Tyr Pro Gly Val Gly Pro Gln His 310 315 320 325 gca cac ctg cac gcc acc ggc cgc gcc acc tac gtt ggt atc acc gac 1123 Ala His Leu His Ala Thr Gly Arg Ala Thr Tyr Val Gly Ile Thr Asp 330 335 340 gcc gaa gcc ctc caa gca ttc cag tac ctc gcc cgc tac gaa ggc atc 1171 Ala Glu Ala Leu Gln Ala Phe Gln Tyr Leu Ala Arg Tyr Glu Gly Ile 345 350 355 atc ccc gca ctg gaa tcc tca cac gcg ttc gcc tac gca ctc aag cgc 1219 Ile Pro Ala Leu Glu Ser Ser His Ala Phe Ala Tyr Ala Leu Lys Arg 360 365 370 gcc aag acc gcc 1231 Ala Lys Thr Ala 375 <210> 448 <211> 377 <212> PRT <213> Corynebacterium glutamicum <400> 448 Met Thr Glu Lys Glu Asn Leu Gly Gly Ser Thr Leu Leu Pro Ala Tyr 1 5 10 15 Phe Gly Glu Phe Gly Gly Gln Phe Val Ala Glu Ser Leu Leu Pro Ala 20 25 30 Leu Asp Gln Leu Glu Lys Ala Phe Val Asp Ala Thr Asn Ser Pro Glu 35 40 45 Phe Arg Glu Glu Leu Gly Gly Tyr Leu Arg Asp Tyr Leu Gly Arg Pro 50 55 60 Thr Pro Leu Thr Glu Cys Ser Asn Leu Pro Leu Ala Gly Glu Gly Lys 65 70 75 80 Gly Phe Ala Arg Ile Phe Leu Lys Arg Glu Asp Leu Val His Gly Gly 85 90 95 Ala His Lys Thr Asn Gln Val Ile Gly Gln Val Leu Leu Ala Lys Arg 100 105 110 Met Gly Lys Thr Arg Ile Ile Ala Glu Thr Gly Ala Gly Gln His Gly 115 120 125 Thr Ala Thr Ala Leu Ala Cys Ala Leu Met Gly Leu Glu Cys Val Val 130 135 140 Tyr Met Gly Ala Lys Asp Val Ala Arg Gln Gln Pro Asn Val Tyr Arg 145 150 155 160 Met Gln Leu His Gly Ala Lys Val Ile Pro Val Glu Ser Gly Ser Gly 165 170 175 Thr Leu Lys Asp Ala Val Asn Glu Ala Leu Arg Asp Trp Thr Ala Thr 180 185 190 Phe His Glu Ser His Tyr Leu Leu Gly Thr Pro Ala Gly Pro His Pro 195 200 205 Phe Pro Thr Ile Val Arg Glu Phe His Lys Val Ile Ser Glu Glu Ala 210 215 220 Lys Ala Gln Met Leu Glu Arg Thr Gly Lys Leu Pro Asp Val Val Val 225 230 235 240 Ala Cys Val Gly Gly Gly Ser Asn Ala Ile Gly Met Phe Ala Asp Phe 245 250 255 Ile Asp Asp Glu Gly Val Glu Leu Val Gly Ala Glu Pro Ala Gly Glu 260 265 270 Gly Leu Asp Ser Gly Lys His Gly Ala Thr Ile Thr Asn Gly Gln Ile 275 280 285 Gly Ile Leu His Gly Thr Arg Ser Tyr Leu Met Arg Asn Ser Asp Gly 290 295 300 Gln Val Glu Glu Ser Tyr Ser Ile Ser Ala Gly Leu Asp Tyr Pro Gly 305 310 315 320 Val Gly Pro Gln His Ala His Leu His Ala Thr Gly Arg Ala Thr Tyr 325 330 335 Val Gly Ile Thr Asp Ala Glu Ala Leu Gln Ala Phe Gln Tyr Leu Ala 340 345 350 Arg Tyr Glu Gly Ile Ile Pro Ala Leu Glu Ser Ser His Ala Phe Ala 355 360 365 Tyr Ala Leu Lys Arg Ala Lys Thr Ala 370 375 <210> 449 <211> 1401 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1378) <223> RXA00064 <400> 449 tcccctaaaa cgtctagagt agtggcttga ggtcactgct ctttttttgt gccctttttt 60 ggtccgtcta ttttgccacc acatgcggag gtacgcagtt atg agt tca gtt tcg 115 Met Ser Ser Val Ser 1 5 ctg cag gat ttt gat gca gag cga att ggt ttg ttc cac gag gac att 163 Leu Gln Asp Phe Asp Ala Glu Arg Ile Gly Leu Phe His Glu Asp Ile 10 15 20 aag cgc aag ttt gat gag ctc aag tca aaa aat ctg aag ctg gat ctt 211 Lys Arg Lys Phe Asp Glu Leu Lys Ser Lys Asn Leu Lys Leu Asp Leu 25 30 35 act cgc ggt aag cct tcg tcg gag cag ttg gat ttc gct gat gag ttg 259 Thr Arg Gly Lys Pro Ser Ser Glu Gln Leu Asp Phe Ala Asp Glu Leu 40 45 50 ttg gcg ttg cct ggt aag ggt gat ttc aag gct gcg gat ggt act gat 307 Leu Ala Leu Pro Gly Lys Gly Asp Phe Lys Ala Ala Asp Gly Thr Asp 55 60 65 gtc cgt aac tat ggc ggg ctg gat ggc atc gtt gat att cgc cag att 355 Val Arg Asn Tyr Gly Gly Leu Asp Gly Ile Val Asp Ile Arg Gln Ile 70 75 80 85 tgg gcg gat ttg ctg ggt gtt cct gtg gag cag gtc ttg gcg ggg gat 403 Trp Ala Asp Leu Leu Gly Val Pro Val Glu Gln Val Leu Ala Gly Asp 90 95 100 gct tcg agc ttg aac atc atg ttt gat gtg atc agc tgg tcg tac att 451 Ala Ser Ser Leu Asn Ile Met Phe Asp Val Ile Ser Trp Ser Tyr Ile 105 110 115 ttc ggt aac aat gat tcg gtt cag cct tgg tcg aag gaa gaa acc gtt 499 Phe Gly Asn Asn Asp Ser Val Gln Pro Trp Ser Lys Glu Glu Thr Val 120 125 130 aag tgg att tgc cct gtt ccg ggc tat gat cgc cat ttc tcc atc acg 547 Lys Trp Ile Cys Pro Val Pro Gly Tyr Asp Arg His Phe Ser Ile Thr 135 140 145 gag cgt ttc ggc ttt gag atg att tct gtg cca atg aat gaa gac ggc 595 Glu Arg Phe Gly Phe Glu Met Ile Ser Val Pro Met Asn Glu Asp Gly 150 155 160 165 cct gat atg gat gct gtt gag gaa ttg gtg aag aat ccg cag gtt aag 643 Pro Asp Met Asp Ala Val Glu Glu Leu Val Lys Asn Pro Gln Val Lys 170 175 180 ggc atg tgg gtt gtt ccg gtg ttt tct aac ccg act ggt ttc acg gtg 691 Gly Met Trp Val Val Pro Val Phe Ser Asn Pro Thr Gly Phe Thr Val 185 190 195 aca gaa gac gtc gca aag cgt cta agc gca atg gaa acc gca gct ccg 739 Thr Glu Asp Val Ala Lys Arg Leu Ser Ala Met Glu Thr Ala Ala Pro 200 205 210 gac ttc cgc gtt gtg tgg gat aat gcc tac gcc gtt cat acg ctg acc 787 Asp Phe Arg Val Val Trp Asp Asn Ala Tyr Ala Val His Thr Leu Thr 215 220 225 gat gaa ttc cct gag gtt atc gat atc gtc ggg ctt ggt gag gcc gct 835 Asp Glu Phe Pro Glu Val Ile Asp Ile Val Gly Leu Gly Glu Ala Ala 230 235 240 245 ggc aac ccg aac cgt ttc tgg gcg ttc act tct act tcg aag atc act 883 Gly Asn Pro Asn Arg Phe Trp Ala Phe Thr Ser Thr Ser Lys Ile Thr 250 255 260 ctc gcg ggt gcg ggc gtg tcg ttc ttc ctc acc tct gcg gag aac cgc 931 Leu Ala Gly Ala Gly Val Ser Phe Phe Leu Thr Ser Ala Glu Asn Arg 265 270 275 aag tgg tac acc ggc cat gcg ggt atc cgt ggc att ggc cct aac aag 979 Lys Trp Tyr Thr Gly His Ala Gly Ile Arg Gly Ile Gly Pro Asn Lys 280 285 290 gtc aat cag ttg gct cat gcg cgt tac ttt ggc gat gct gag gga gtg 1027 Val Asn Gln Leu Ala His Ala Arg Tyr Phe Gly Asp Ala Glu Gly Val 295 300 305 cgc gcg gtg atg cgt aag cat gct gcg tcg ttg gct ccg aag ttc aac 1075 Arg Ala Val Met Arg Lys His Ala Ala Ser Leu Ala Pro Lys Phe Asn 310 315 320 325 aag gtt ctg gag att ctg gat tct cgc ctt gct gag tac ggt gtc gcg 1123 Lys Val Leu Glu Ile Leu Asp Ser Arg Leu Ala Glu Tyr Gly Val Ala 330 335 340 cag tgg act gtc cct gcg ggc ggt tac ttc att tcc ctt gat gtg gtt 1171 Gln Trp Thr Val Pro Ala Gly Gly Tyr Phe Ile Ser Leu Asp Val Val 345 350 355 cct ggt acg gcg tct cgc gtg gct gag ttg gct aag gaa gcc ggc atc 1219 Pro Gly Thr Ala Ser Arg Val Ala Glu Leu Ala Lys Glu Ala Gly Ile 360 365 370 gcg ttg acg ggt gcg ggt tct tct tac ccg ctg cgt cag gat ccg gag 1267 Ala Leu Thr Gly Ala Gly Ser Ser Tyr Pro Leu Arg Gln Asp Pro Glu 375 380 385 aac aaa aat ctc cgt ttg gca ccg tcg ctg cct cca gtt gag gaa ctt 1315 Asn Lys Asn Leu Arg Leu Ala Pro Ser Leu Pro Pro Val Glu Glu Leu 390 395 400 405 gag gtt gcc atg gat ggc gtg gct acc tgt gtg ctg ttg gca gca gcg 1363 Glu Val Ala Met Asp Gly Val Ala Thr Cys Val Leu Leu Ala Ala Ala 410 415 420 gag cat tac gct aac taaaagtgaa tacagcggag aca 1401 Glu His Tyr Ala Asn 425 <210> 450 <211> 426 <212> PRT <213> Corynebacterium glutamicum <400> 450 Met Ser Ser Val Ser Leu Gln Asp Phe Asp Ala Glu Arg Ile Gly Leu 1 5 10 15 Phe His Glu Asp Ile Lys Arg Lys Phe Asp Glu Leu Lys Ser Lys Asn 20 25 30 Leu Lys Leu Asp Leu Thr Arg Gly Lys Pro Ser Ser Glu Gln Leu Asp 35 40 45 Phe Ala Asp Glu Leu Leu Ala Leu Pro Gly Lys Gly Asp Phe Lys Ala 50 55 60 Ala Asp Gly Thr Asp Val Arg Asn Tyr Gly Gly Leu Asp Gly Ile Val 65 70 75 80 Asp Ile Arg Gln Ile Trp Ala Asp Leu Leu Gly Val Pro Val Glu Gln 85 90 95 Val Leu Ala Gly Asp Ala Ser Ser Leu Asn Ile Met Phe Asp Val Ile 100 105 110 Ser Trp Ser Tyr Ile Phe Gly Asn Asn Asp Ser Val Gln Pro Trp Ser 115 120 125 Lys Glu Glu Thr Val Lys Trp Ile Cys Pro Val Pro Gly Tyr Asp Arg 130 135 140 His Phe Ser Ile Thr Glu Arg Phe Gly Phe Glu Met Ile Ser Val Pro 145 150 155 160 Met Asn Glu Asp Gly Pro Asp Met Asp Ala Val Glu Glu Leu Val Lys 165 170 175 Asn Pro Gln Val Lys Gly Met Trp Val Val Pro Val Phe Ser Asn Pro 180 185 190 Thr Gly Phe Thr Val Thr Glu Asp Val Ala Lys Arg Leu Ser Ala Met 195 200 205 Glu Thr Ala Ala Pro Asp Phe Arg Val Val Trp Asp Asn Ala Tyr Ala 210 215 220 Val His Thr Leu Thr Asp Glu Phe Pro Glu Val Ile Asp Ile Val Gly 225 230 235 240 Leu Gly Glu Ala Ala Gly Asn Pro Asn Arg Phe Trp Ala Phe Thr Ser 245 250 255 Thr Ser Lys Ile Thr Leu Ala Gly Ala Gly Val Ser Phe Phe Leu Thr 260 265 270 Ser Ala Glu Asn Arg Lys Trp Tyr Thr Gly His Ala Gly Ile Arg Gly 275 280 285 Ile Gly Pro Asn Lys Val Asn Gln Leu Ala His Ala Arg Tyr Phe Gly 290 295 300 Asp Ala Glu Gly Val Arg Ala Val Met Arg Lys His Ala Ala Ser Leu 305 310 315 320 Ala Pro Lys Phe Asn Lys Val Leu Glu Ile Leu Asp Ser Arg Leu Ala 325 330 335 Glu Tyr Gly Val Ala Gln Trp Thr Val Pro Ala Gly Gly Tyr Phe Ile 340 345 350 Ser Leu Asp Val Val Pro Gly Thr Ala Ser Arg Val Ala Glu Leu Ala 355 360 365 Lys Glu Ala Gly Ile Ala Leu Thr Gly Ala Gly Ser Ser Tyr Pro Leu 370 375 380 Arg Gln Asp Pro Glu Asn Lys Asn Leu Arg Leu Ala Pro Ser Leu Pro 385 390 395 400 Pro Val Glu Glu Leu Glu Val Ala Met Asp Gly Val Ala Thr Cys Val 405 410 415 Leu Leu Ala Ala Ala Glu His Tyr Ala Asn 420 425 <210> 451 <211> 1143 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1120) <223> RXN00448 <400> 451 ccatttacct tcaactaagg tagccgtaac tgcaaagctc aggccatcct cttcagtgtt 60 catagagata accgtagtag gtatgtgcca cacttgtcag gtg act acc aaa gac 115 Val Thr Thr Lys Asp 1 5 att tcc cgc cca gta tgc atc ctg ggc ctc ggc ctc atc ggc gga tcc 163 Ile Ser Arg Pro Val Cys Ile Leu Gly Leu Gly Leu Ile Gly Gly Ser 10 15 20 ctc ctc cgc gac ctc cat gca gcc aac cac tcc gtc ttc ggc tac aac 211 Leu Leu Arg Asp Leu His Ala Ala Asn His Ser Val Phe Gly Tyr Asn 25 30 35 cgc tca cgc tcc ggc gct aaa tca gcc gtc gac gaa ggc ttc gac gtt 259 Arg Ser Arg Ser Gly Ala Lys Ser Ala Val Asp Glu Gly Phe Asp Val 40 45 50 tcc gcc gat ctt gaa gca acc ctc cag cgt gca gcc gcc gaa gat gcg 307 Ser Ala Asp Leu Glu Ala Thr Leu Gln Arg Ala Ala Ala Glu Asp Ala 55 60 65 ctc atc gtc ctc gcg gtc ccc atg acc gca atc gat tcg ctt ctc gac 355 Leu Ile Val Leu Ala Val Pro Met Thr Ala Ile Asp Ser Leu Leu Asp 70 75 80 85 gcc gtc cac acc cac gca cca aac aac ggc ttc acc gac gtc gta tcc 403 Ala Val His Thr His Ala Pro Asn Asn Gly Phe Thr Asp Val Val Ser 90 95 100 gta aaa acc gcc gtc tac gac gca gta aaa gcc cgc aac atg caa cac 451 Val Lys Thr Ala Val Tyr Asp Ala Val Lys Ala Arg Asn Met Gln His 105 110 115 cgt tat gtg gga tcc cac ccc atg gca ggc acc gcc aac tcc ggc tgg 499 Arg Tyr Val Gly Ser His Pro Met Ala Gly Thr Ala Asn Ser Gly Trp 120 125 130 agc gca tcc atg gac gga ctg ttc aaa cga gca gta tgg gtg gtc acc 547 Ser Ala Ser Met Asp Gly Leu Phe Lys Arg Ala Val Trp Val Val Thr 135 140 145 ttc gac cag ctt ttc gac ggc acc gac atc aac tcc acc tgg atc agc 595 Phe Asp Gln Leu Phe Asp Gly Thr Asp Ile Asn Ser Thr Trp Ile Ser 150 155 160 165 atc tgg aaa gac gtc gtc caa atg gca ctc gcc gtg ggc gct gaa gtt 643 Ile Trp Lys Asp Val Val Gln Met Ala Leu Ala Val Gly Ala Glu Val 170 175 180 gtc cca tcc cga gtt ggc cca cac gat gca gca gca gca cga gtg tct 691 Val Pro Ser Arg Val Gly Pro His Asp Ala Ala Ala Ala Arg Val Ser 185 190 195 cat tta aca cac atc ctg gct gaa acc ctc gcc atc gtc ggt gac aac 739 His Leu Thr His Ile Leu Ala Glu Thr Leu Ala Ile Val Gly Asp Asn 200 205 210 ggt ggc gca ctg tct ctc tct tta gcc gct ggc agc tac cgc gac tcc 787 Gly Gly Ala Leu Ser Leu Ser Leu Ala Ala Gly Ser Tyr Arg Asp Ser 215 220 225 acc cgc gtt gca ggc acc gac cca gga ctc gtc cgc gcc atg tgt gaa 835 Thr Arg Val Ala Gly Thr Asp Pro Gly Leu Val Arg Ala Met Cys Glu 230 235 240 245 agc aac gcc ggc cca ctg gtc aaa gcc ctc gac gaa gca ctg gcg atc 883 Ser Asn Ala Gly Pro Leu Val Lys Ala Leu Asp Glu Ala Leu Ala Ile 250 255 260 ctc cac gaa gcc cgc gaa ggc ctc acc gca gaa cag cca aac atc gag 931 Leu His Glu Ala Arg Glu Gly Leu Thr Ala Glu Gln Pro Asn Ile Glu 265 270 275 caa ctt gcc gac aac ggc tac cga tcc cgc atc cgc tac gaa gcc cgc 979 Gln Leu Ala Asp Asn Gly Tyr Arg Ser Arg Ile Arg Tyr Glu Ala Arg 280 285 290 tcc ggc cag cga cgc gcc aaa gaa tcc gtt agc cct acc atc acc tca 1027 Ser Gly Gln Arg Arg Ala Lys Glu Ser Val Ser Pro Thr Ile Thr Ser 295 300 305 tcc agg cca gtg ctc cgt ctc cac ccg ggc aca cca aac tgg gag aag 1075 Ser Arg Pro Val Leu Arg Leu His Pro Gly Thr Pro Asn Trp Glu Lys 310 315 320 325 cag ctc atc cac gct gaa acc ctc ggc gca cgg atc gaa gtg ttc 1120 Gln Leu Ile His Ala Glu Thr Leu Gly Ala Arg Ile Glu Val Phe 330 335 340 tagttttatc ggctgatgat tct 1143 <210> 452 <211> 340 <212> PRT <213> Corynebacterium glutamicum <400> 452 Val Thr Thr Lys Asp Ile Ser Arg Pro Val Cys Ile Leu Gly Leu Gly 1 5 10 15 Leu Ile Gly Gly Ser Leu Leu Arg Asp Leu His Ala Ala Asn His Ser 20 25 30 Val Phe Gly Tyr Asn Arg Ser Arg Ser Gly Ala Lys Ser Ala Val Asp 35 40 45 Glu Gly Phe Asp Val Ser Ala Asp Leu Glu Ala Thr Leu Gln Arg Ala 50 55 60 Ala Ala Glu Asp Ala Leu Ile Val Leu Ala Val Pro Met Thr Ala Ile 65 70 75 80 Asp Ser Leu Leu Asp Ala Val His Thr His Ala Pro Asn Asn Gly Phe 85 90 95 Thr Asp Val Val Ser Val Lys Thr Ala Val Tyr Asp Ala Val Lys Ala 100 105 110 Arg Asn Met Gln His Arg Tyr Val Gly Ser His Pro Met Ala Gly Thr 115 120 125 Ala Asn Ser Gly Trp Ser Ala Ser Met Asp Gly Leu Phe Lys Arg Ala 130 135 140 Val Trp Val Val Thr Phe Asp Gln Leu Phe Asp Gly Thr Asp Ile Asn 145 150 155 160 Ser Thr Trp Ile Ser Ile Trp Lys Asp Val Val Gln Met Ala Leu Ala 165 170 175 Val Gly Ala Glu Val Val Pro Ser Arg Val Gly Pro His Asp Ala Ala 180 185 190 Ala Ala Arg Val Ser His Leu Thr His Ile Leu Ala Glu Thr Leu Ala 195 200 205 Ile Val Gly Asp Asn Gly Gly Ala Leu Ser Leu Ser Leu Ala Ala Gly 210 215 220 Ser Tyr Arg Asp Ser Thr Arg Val Ala Gly Thr Asp Pro Gly Leu Val 225 230 235 240 Arg Ala Met Cys Glu Ser Asn Ala Gly Pro Leu Val Lys Ala Leu Asp 245 250 255 Glu Ala Leu Ala Ile Leu His Glu Ala Arg Glu Gly Leu Thr Ala Glu 260 265 270 Gln Pro Asn Ile Glu Gln Leu Ala Asp Asn Gly Tyr Arg Ser Arg Ile 275 280 285 Arg Tyr Glu Ala Arg Ser Gly Gln Arg Arg Ala Lys Glu Ser Val Ser 290 295 300 Pro Thr Ile Thr Ser Ser Arg Pro Val Leu Arg Leu His Pro Gly Thr 305 310 315 320 Pro Asn Trp Glu Lys Gln Leu Ile His Ala Glu Thr Leu Gly Ala Arg 325 330 335 Ile Glu Val Phe 340 <210> 453 <211> 689 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(666) <223> FRXA00448 <400> 453 tat gtg gga tcc cac ccc atg gca ggc acc gcc aac tcc ggc tgg agc 48 Tyr Val Gly Ser His Pro Met Ala Gly Thr Ala Asn Ser Gly Trp Ser 1 5 10 15 gca tcc atg gac gga ctg ttc aaa cga gca gta tgg gtg gtc acc ttc 96 Ala Ser Met Asp Gly Leu Phe Lys Arg Ala Val Trp Val Val Thr Phe 20 25 30 gac cag ctt ttc gac ggc acc gac atc aac tcc acc tgg atc agc atc 144 Asp Gln Leu Phe Asp Gly Thr Asp Ile Asn Ser Thr Trp Ile Ser Ile 35 40 45 tgg aaa gac gtc gtc caa atg gca ctc gcc gtg ggc gct gaa gtt gtc 192 Trp Lys Asp Val Val Gln Met Ala Leu Ala Val Gly Ala Glu Val Val 50 55 60 cca tcc cga gtt ggc cca cac gat gca gca gca gca cga gtg tct cat 240 Pro Ser Arg Val Gly Pro His Asp Ala Ala Ala Ala Arg Val Ser His 65 70 75 80 tta aca cac atc ctg gct gaa acc ctc gcc atc gtc ggt gac aac ggt 288 Leu Thr His Ile Leu Ala Glu Thr Leu Ala Ile Val Gly Asp Asn Gly 85 90 95 ggc gca ctg tct ctc tct tta gcc gct ggc agc tac cgc gac tcc acc 336 Gly Ala Leu Ser Leu Ser Leu Ala Ala Gly Ser Tyr Arg Asp Ser Thr 100 105 110 cgc gtt gca ggc acc gac cca gga ctc gtc cgc gcc atg tgt gaa agc 384 Arg Val Ala Gly Thr Asp Pro Gly Leu Val Arg Ala Met Cys Glu Ser 115 120 125 aac gcc ggc cca ctg gtc aaa gcc ctc gac gaa gca ctg gcg atc ctc 432 Asn Ala Gly Pro Leu Val Lys Ala Leu Asp Glu Ala Leu Ala Ile Leu 130 135 140 cac gaa gcc cgc gaa ggc ctc acc gca gaa cag cca aac atc gag caa 480 His Glu Ala Arg Glu Gly Leu Thr Ala Glu Gln Pro Asn Ile Glu Gln 145 150 155 160 ctt gcc gac aac ggc tac cga tcc cgc atc cgc tac gaa gcc cgc tcc 528 Leu Ala Asp Asn Gly Tyr Arg Ser Arg Ile Arg Tyr Glu Ala Arg Ser 165 170 175 ggc cag cga cgc gcc aaa gaa tcc gtt agc cct acc atc acc tca tcc 576 Gly Gln Arg Arg Ala Lys Glu Ser Val Ser Pro Thr Ile Thr Ser Ser 180 185 190 agg cca gtg ctc cgt ctc cac ccg ggc aca cca aac tgg gag aag cag 624 Arg Pro Val Leu Arg Leu His Pro Gly Thr Pro Asn Trp Glu Lys Gln 195 200 205 ctc atc cac gct gaa acc ctc ggc gca cgg atc gaa gtg ttc 666 Leu Ile His Ala Glu Thr Leu Gly Ala Arg Ile Glu Val Phe 210 215 220 tagttttatc ggctgatgat tct 689 <210> 454 <211> 222 <212> PRT <213> Corynebacterium glutamicum <400> 454 Tyr Val Gly Ser His Pro Met Ala Gly Thr Ala Asn Ser Gly Trp Ser 1 5 10 15 Ala Ser Met Asp Gly Leu Phe Lys Arg Ala Val Trp Val Val Thr Phe 20 25 30 Asp Gln Leu Phe Asp Gly Thr Asp Ile Asn Ser Thr Trp Ile Ser Ile 35 40 45 Trp Lys Asp Val Val Gln Met Ala Leu Ala Val Gly Ala Glu Val Val 50 55 60 Pro Ser Arg Val Gly Pro His Asp Ala Ala Ala Ala Arg Val Ser His 65 70 75 80 Leu Thr His Ile Leu Ala Glu Thr Leu Ala Ile Val Gly Asp Asn Gly 85 90 95 Gly Ala Leu Ser Leu Ser Leu Ala Ala Gly Ser Tyr Arg Asp Ser Thr 100 105 110 Arg Val Ala Gly Thr Asp Pro Gly Leu Val Arg Ala Met Cys Glu Ser 115 120 125 Asn Ala Gly Pro Leu Val Lys Ala Leu Asp Glu Ala Leu Ala Ile Leu 130 135 140 His Glu Ala Arg Glu Gly Leu Thr Ala Glu Gln Pro Asn Ile Glu Gln 145 150 155 160 Leu Ala Asp Asn Gly Tyr Arg Ser Arg Ile Arg Tyr Glu Ala Arg Ser 165 170 175 Gly Gln Arg Arg Ala Lys Glu Ser Val Ser Pro Thr Ile Thr Ser Ser 180 185 190 Arg Pro Val Leu Arg Leu His Pro Gly Thr Pro Asn Trp Glu Lys Gln 195 200 205 Leu Ile His Ala Glu Thr Leu Gly Ala Arg Ile Glu Val Phe 210 215 220 <210> 455 <211> 346 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(346) <223> FRXA00452 <400> 455 ccatttacct tcaactaagg tagccgtaac tgcaaagctc aggccatcct cttcagtgtt 60 catagagata accgtagtag gtatgtgcca cacttgtcag gtg act acc aaa gac 115 Val Thr Thr Lys Asp 1 5 att tcc cgc cca gta tgc atc ctg ggc ctc ggc ctc atc ggc gga tcc 163 Ile Ser Arg Pro Val Cys Ile Leu Gly Leu Gly Leu Ile Gly Gly Ser 10 15 20 ctc ctc cgc gac ctc cat gca gcc aac cac tcc gtc ttc ggc tac aac 211 Leu Leu Arg Asp Leu His Ala Ala Asn His Ser Val Phe Gly Tyr Asn 25 30 35 cgc tca cgc tcc ggc gct aaa tca gcc gtc gac gaa ggc ttc gac gtt 259 Arg Ser Arg Ser Gly Ala Lys Ser Ala Val Asp Glu Gly Phe Asp Val 40 45 50 tcc gcc gat ctt gaa gca acc ctc cag cgt gca gcc gcc gaa gat gcg 307 Ser Ala Asp Leu Glu Ala Thr Leu Gln Arg Ala Ala Ala Glu Asp Ala 55 60 65 ctc atc gtc ctc gcg gtc ccc atg acc gca atc gat tcg 346 Leu Ile Val Leu Ala Val Pro Met Thr Ala Ile Asp Ser 70 75 80 <210> 456 <211> 82 <212> PRT <213> Corynebacterium glutamicum <400> 456 Val Thr Thr Lys Asp Ile Ser Arg Pro Val Cys Ile Leu Gly Leu Gly 1 5 10 15 Leu Ile Gly Gly Ser Leu Leu Arg Asp Leu His Ala Ala Asn His Ser 20 25 30 Val Phe Gly Tyr Asn Arg Ser Arg Ser Gly Ala Lys Ser Ala Val Asp 35 40 45 Glu Gly Phe Asp Val Ser Ala Asp Leu Glu Ala Thr Leu Gln Arg Ala 50 55 60 Ala Ala Glu Asp Ala Leu Ile Val Leu Ala Val Pro Met Thr Ala Ile 65 70 75 80 Asp Ser <210> 457 <211> 1248 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1225) <223> RXA00584 <400> 457 tagttgtgcc acctaaaacg cgaacagaac cggagtcgag cagcacctcc ccgcaagggt 60 agaggggctg cttttttgtt tcctaaattc accccatccc atg cat agc cct gaa 115 Met His Ser Pro Glu 1 5 agg caa gaa aaa atg agt tct cca gtc tca ctc gaa aac gcg gcg tca 163 Arg Gln Glu Lys Met Ser Ser Pro Val Ser Leu Glu Asn Ala Ala Ser 10 15 20 acc agc aac aag cgc gtc gtg gct ttc cac gag ctg cct agc cct aca 211 Thr Ser Asn Lys Arg Val Val Ala Phe His Glu Leu Pro Ser Pro Thr 25 30 35 gat ctc atc gcc gca aac cca ctg aca cca aag cag gct tcc aag gtg 259 Asp Leu Ile Ala Ala Asn Pro Leu Thr Pro Lys Gln Ala Ser Lys Val 40 45 50 gag cag gat cgc cag gac atc gct gat atc ttc gct ggc gac gat gac 307 Glu Gln Asp Arg Gln Asp Ile Ala Asp Ile Phe Ala Gly Asp Asp Asp 55 60 65 cgc ctc gtt gtc gtt gtg gga cct tgc tca gtt cac gat cct gaa gca 355 Arg Leu Val Val Val Val Gly Pro Cys Ser Val His Asp Pro Glu Ala 70 75 80 85 gcc atc gat tac gca aac cgc ctg gct ccg ctg gca aag cgc ctt gat 403 Ala Ile Asp Tyr Ala Asn Arg Leu Ala Pro Leu Ala Lys Arg Leu Asp 90 95 100 cag gac ctc aag att gtc atg cgc gtg tac ttc gag aag cct cgc acc 451 Gln Asp Leu Lys Ile Val Met Arg Val Tyr Phe Glu Lys Pro Arg Thr 105 110 115 atc gtc gga tgg aag gga ttg atc aat gat cct cac ctc aac gaa acc 499 Ile Val Gly Trp Lys Gly Leu Ile Asn Asp Pro His Leu Asn Glu Thr 120 125 130 tac gac atc cca gag ggc ttg cgc att gcg cgc aaa gtg ctt atc gac 547 Tyr Asp Ile Pro Glu Gly Leu Arg Ile Ala Arg Lys Val Leu Ile Asp 135 140 145 gtt gtg aac ctt gat ctc cca gtc ggc tgc gaa ttc ctc gaa cca aac 595 Val Val Asn Leu Asp Leu Pro Val Gly Cys Glu Phe Leu Glu Pro Asn 150 155 160 165 agc cct cag tac tac gcc gac act gtc gca tgg gga gca atc ggc gct 643 Ser Pro Gln Tyr Tyr Ala Asp Thr Val Ala Trp Gly Ala Ile Gly Ala 170 175 180 cgt acc acc gaa tct cag gtg cac cgc cag ctg gct tct ggg atg tct 691 Arg Thr Thr Glu Ser Gln Val His Arg Gln Leu Ala Ser Gly Met Ser 185 190 195 atg cca att ggt ttc aag aac gga act gac gga aac atc cag gtt gca 739 Met Pro Ile Gly Phe Lys Asn Gly Thr Asp Gly Asn Ile Gln Val Ala 200 205 210 gtc gac gcg gta cag gct gcc cag aac cca cac ttc ttc ttc gga acc 787 Val Asp Ala Val Gln Ala Ala Gln Asn Pro His Phe Phe Phe Gly Thr 215 220 225 tcc gac gac ggc gcg ctg agc gtc gtg gag acc gca ggc aac agc aac 835 Ser Asp Asp Gly Ala Leu Ser Val Val Glu Thr Ala Gly Asn Ser Asn 230 235 240 245 tcc cac atc att ttg cgc ggc ggt acc tcc ggc ccg aat cat gat gca 883 Ser His Ile Ile Leu Arg Gly Gly Thr Ser Gly Pro Asn His Asp Ala 250 255 260 gct tcg gtg gag gcc gtc gtc gag aag ctt ggt gaa aac gct cgt ctc 931 Ala Ser Val Glu Ala Val Val Glu Lys Leu Gly Glu Asn Ala Arg Leu 265 270 275 atg atc gat gct tcc cat gct aac tcc ggc aag gat cat atc cga cag 979 Met Ile Asp Ala Ser His Ala Asn Ser Gly Lys Asp His Ile Arg Gln 280 285 290 gtt gag gtt gtt cgt gaa atc gca gag cag att tct ggc ggt tct gaa 1027 Val Glu Val Val Arg Glu Ile Ala Glu Gln Ile Ser Gly Gly Ser Glu 295 300 305 gct gtg gct gga atc atg att gag tcc ttc ctc gtt ggt ggc gca cag 1075 Ala Val Ala Gly Ile Met Ile Glu Ser Phe Leu Val Gly Gly Ala Gln 310 315 320 325 aac ctt gat cct gcg aaa ttg cgc atc aat ggc ggt gaa ggc ctg gtg 1123 Asn Leu Asp Pro Ala Lys Leu Arg Ile Asn Gly Gly Glu Gly Leu Val 330 335 340 tac gga cag tct gtg acc gat aag tgc atc gat att gac acc acc atc 1171 Tyr Gly Gln Ser Val Thr Asp Lys Cys Ile Asp Ile Asp Thr Thr Ile 345 350 355 gat ttg ctc gct gag ctg gcc gca gca gta agg gaa cgc cga gca gca 1219 Asp Leu Leu Ala Glu Leu Ala Ala Ala Val Arg Glu Arg Arg Ala Ala 360 365 370 gcc aag taattaaggg cgctagactg tta 1248 Ala Lys 375 <210> 458 <211> 375 <212> PRT <213> Corynebacterium glutamicum <400> 458 Met His Ser Pro Glu Arg Gln Glu Lys Met Ser Ser Pro Val Ser Leu 1 5 10 15 Glu Asn Ala Ala Ser Thr Ser Asn Lys Arg Val Val Ala Phe His Glu 20 25 30 Leu Pro Ser Pro Thr Asp Leu Ile Ala Ala Asn Pro Leu Thr Pro Lys 35 40 45 Gln Ala Ser Lys Val Glu Gln Asp Arg Gln Asp Ile Ala Asp Ile Phe 50 55 60 Ala Gly Asp Asp Asp Arg Leu Val Val Val Val Gly Pro Cys Ser Val 65 70 75 80 His Asp Pro Glu Ala Ala Ile Asp Tyr Ala Asn Arg Leu Ala Pro Leu 85 90 95 Ala Lys Arg Leu Asp Gln Asp Leu Lys Ile Val Met Arg Val Tyr Phe 100 105 110 Glu Lys Pro Arg Thr Ile Val Gly Trp Lys Gly Leu Ile Asn Asp Pro 115 120 125 His Leu Asn Glu Thr Tyr Asp Ile Pro Glu Gly Leu Arg Ile Ala Arg 130 135 140 Lys Val Leu Ile Asp Val Val Asn Leu Asp Leu Pro Val Gly Cys Glu 145 150 155 160 Phe Leu Glu Pro Asn Ser Pro Gln Tyr Tyr Ala Asp Thr Val Ala Trp 165 170 175 Gly Ala Ile Gly Ala Arg Thr Thr Glu Ser Gln Val His Arg Gln Leu 180 185 190 Ala Ser Gly Met Ser Met Pro Ile Gly Phe Lys Asn Gly Thr Asp Gly 195 200 205 Asn Ile Gln Val Ala Val Asp Ala Val Gln Ala Ala Gln Asn Pro His 210 215 220 Phe Phe Phe Gly Thr Ser Asp Asp Gly Ala Leu Ser Val Val Glu Thr 225 230 235 240 Ala Gly Asn Ser Asn Ser His Ile Ile Leu Arg Gly Gly Thr Ser Gly 245 250 255 Pro Asn His Asp Ala Ala Ser Val Glu Ala Val Val Glu Lys Leu Gly 260 265 270 Glu Asn Ala Arg Leu Met Ile Asp Ala Ser His Ala Asn Ser Gly Lys 275 280 285 Asp His Ile Arg Gln Val Glu Val Val Arg Glu Ile Ala Glu Gln Ile 290 295 300 Ser Gly Gly Ser Glu Ala Val Ala Gly Ile Met Ile Glu Ser Phe Leu 305 310 315 320 Val Gly Gly Ala Gln Asn Leu Asp Pro Ala Lys Leu Arg Ile Asn Gly 325 330 335 Gly Glu Gly Leu Val Tyr Gly Gln Ser Val Thr Asp Lys Cys Ile Asp 340 345 350 Ile Asp Thr Thr Ile Asp Leu Leu Ala Glu Leu Ala Ala Ala Val Arg 355 360 365 Glu Arg Arg Ala Ala Ala Lys 370 375 <210> 459 <211> 1983 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1960) <223> RXA00579 <400> 459 tcgtctaagt ttttctttga gttttcatat gtagaaggca tcgtcggctt cggcctggcg 60 gtgcttttct cgttgttttg tggttttgtc agaggatgtc atg cgc gtt tta att 115 Met Arg Val Leu Ile 1 5 att gat aat tat gat tct ttc acg ttt aat ctc gcc acc tat gtg gaa 163 Ile Asp Asn Tyr Asp Ser Phe Thr Phe Asn Leu Ala Thr Tyr Val Glu 10 15 20 gag gtt acg ggt cag gca cct gtg gtg gtg cct aat gat caa gaa ata 211 Glu Val Thr Gly Gln Ala Pro Val Val Val Pro Asn Asp Gln Glu Ile 25 30 35 gat gag atg ctt ttc gac gcc gtc atc ctc tca cct ggc ccg ggc cac 259 Asp Glu Met Leu Phe Asp Ala Val Ile Leu Ser Pro Gly Pro Gly His 40 45 50 gcc ggc gtt gcg gct gat ttt ggt atc tgt gca ggc gtc att gag cgt 307 Ala Gly Val Ala Ala Asp Phe Gly Ile Cys Ala Gly Val Ile Glu Arg 55 60 65 gca cgc gtt ccg att ttg ggt gtg tgt tta ggc cac cag ggc att gcg 355 Ala Arg Val Pro Ile Leu Gly Val Cys Leu Gly His Gln Gly Ile Ala 70 75 80 85 ttg gcc tat ggc ggt gat gtt gat ttg gcg ccc agg ccg gtc cac ggt 403 Leu Ala Tyr Gly Gly Asp Val Asp Leu Ala Pro Arg Pro Val His Gly 90 95 100 gag gtt tcg cag atc acc cat gat ggt tca ggt tta ttt gca ggc atc 451 Glu Val Ser Gln Ile Thr His Asp Gly Ser Gly Leu Phe Ala Gly Ile 105 110 115 cct gaa acg ttt gag gcg gtg cgt tat cac tcg atg gtg gca acc cgc 499 Pro Glu Thr Phe Glu Ala Val Arg Tyr His Ser Met Val Ala Thr Arg 120 125 130 ttg ccg gag tca ttg aaa gct aca gct acc agc gat gat ggt ttg atc 547 Leu Pro Glu Ser Leu Lys Ala Thr Ala Thr Ser Asp Asp Gly Leu Ile 135 140 145 atg gca ttg gca cat gaa gtg ctt ccg cag tgg ggt gtg caa ttt cat 595 Met Ala Leu Ala His Glu Val Leu Pro Gln Trp Gly Val Gln Phe His 150 155 160 165 ccg gaa tct att ggt gga caa ttc ggc cat cag atc att aag aac ttc 643 Pro Glu Ser Ile Gly Gly Gln Phe Gly His Gln Ile Ile Lys Asn Phe 170 175 180 ctt aat tta gcg cgc aca tat cgc tgg caa ctc acg gag aaa act att 691 Leu Asn Leu Ala Arg Thr Tyr Arg Trp Gln Leu Thr Glu Lys Thr Ile 185 190 195 ccg ctc agc gtt gat tca gca gcg gtt ttt gaa aca ttc ttt gcc cat 739 Pro Leu Ser Val Asp Ser Ala Ala Val Phe Glu Thr Phe Phe Ala His 200 205 210 tcc tcc cat gct ttt tgg ctc gat gat gcc caa gga acc agc tat ctt 787 Ser Ser His Ala Phe Trp Leu Asp Asp Ala Gln Gly Thr Ser Tyr Leu 215 220 225 ggt gat gcc agc ggt cct ctc gca cgc aca aaa acc cat aat gtc ggc 835 Gly Asp Ala Ser Gly Pro Leu Ala Arg Thr Lys Thr His Asn Val Gly 230 235 240 245 gag ggg gat ttc ttc acc tgg cta aag gag gat ctc gcc gcc aac tca 883 Glu Gly Asp Phe Phe Thr Trp Leu Lys Glu Asp Leu Ala Ala Asn Ser 250 255 260 gtt gcg ccc ggt caa ggt ttt cgt ctt ggc tgg gtt ggt tac gtt ggt 931 Val Ala Pro Gly Gln Gly Phe Arg Leu Gly Trp Val Gly Tyr Val Gly 265 270 275 tat gag ctt aaa gcg gaa gct ggc gca cgg gct gcg cac act tcg agt 979 Tyr Glu Leu Lys Ala Glu Ala Gly Ala Arg Ala Ala His Thr Ser Ser 280 285 290 ctt ccg gat gcg cac ctc att ttt gcc gat cgc gcc atc gca gtg gaa 1027 Leu Pro Asp Ala His Leu Ile Phe Ala Asp Arg Ala Ile Ala Val Glu 295 300 305 tcg gat cag gtt cgg ttg ctg gcg ttg ggg gag cag gac gag tgg ttt 1075 Ser Asp Gln Val Arg Leu Leu Ala Leu Gly Glu Gln Asp Glu Trp Phe 310 315 320 325 gaa gaa acc atc aag aag ctg cat aat ctt gtc gcc ccg cgg ata cct 1123 Glu Glu Thr Ile Lys Lys Leu His Asn Leu Val Ala Pro Arg Ile Pro 330 335 340 gcg tcc gga cac ctc gct ttg cag gtt cga gat tcc aaa gat gag tat 1171 Ala Ser Gly His Leu Ala Leu Gln Val Arg Asp Ser Lys Asp Glu Tyr 345 350 355 ctc gac aaa att cgc aga gcc cag gag ctg att act cgc ggc gaa tcg 1219 Leu Asp Lys Ile Arg Arg Ala Gln Glu Leu Ile Thr Arg Gly Glu Ser 360 365 370 tat gaa atc tgc ctg acc aca aaa ctt cag ggc acc act gat gtg gcc 1267 Tyr Glu Ile Cys Leu Thr Thr Lys Leu Gln Gly Thr Thr Asp Val Ala 375 380 385 cct ctg gct gcc tat cta gca ctg cgt ggg gcc aat ccc acc gca tat 1315 Pro Leu Ala Ala Tyr Leu Ala Leu Arg Gly Ala Asn Pro Thr Ala Tyr 390 395 400 405 ggt gcg tat ctt cag ctg ggg gat acc tct att ttg agt tcc tcg ccg 1363 Gly Ala Tyr Leu Gln Leu Gly Asp Thr Ser Ile Leu Ser Ser Ser Pro 410 415 420 gag cgg ttc atc acc att gat tcg gca ggg tat gtg gaa tca aag ccc 1411 Glu Arg Phe Ile Thr Ile Asp Ser Ala Gly Tyr Val Glu Ser Lys Pro 425 430 435 att aaa ggc acc agg ccg cgt ggg cga aca gcg caa gaa gac caa gaa 1459 Ile Lys Gly Thr Arg Pro Arg Gly Arg Thr Ala Gln Glu Asp Gln Glu 440 445 450 atc att gct gag ctg cgc agt aat cct aaa gat cgt gca gaa aac ttg 1507 Ile Ile Ala Glu Leu Arg Ser Asn Pro Lys Asp Arg Ala Glu Asn Leu 455 460 465 atg atc gtg gat ttg gtc cgc aac gac tta gcc cgc ggc gct ttg ccc 1555 Met Ile Val Asp Leu Val Arg Asn Asp Leu Ala Arg Gly Ala Leu Pro 470 475 480 485 acc aca gtt aaa aca tcc aag ctt ttc gac gtc gaa acc tac gcc aca 1603 Thr Thr Val Lys Thr Ser Lys Leu Phe Asp Val Glu Thr Tyr Ala Thr 490 495 500 gtc cac caa ctt gtc agc acc gtc tct gca gag ttg ggg cca cgc agt 1651 Val His Gln Leu Val Ser Thr Val Ser Ala Glu Leu Gly Pro Arg Ser 505 510 515 ccg att gag tgc gtg cgc gca gca ttc ccc ggt ggt tcg atg act ggt 1699 Pro Ile Glu Cys Val Arg Ala Ala Phe Pro Gly Gly Ser Met Thr Gly 520 525 530 gcc cca aag ctg cgc acc atg gag atc atc gat gag ctg gag gca gct 1747 Ala Pro Lys Leu Arg Thr Met Glu Ile Ile Asp Glu Leu Glu Ala Ala 535 540 545 cct cgc ggt att tac tca ggt ggc ttg gga tat ttt tcc ctc gac ggc 1795 Pro Arg Gly Ile Tyr Ser Gly Gly Leu Gly Tyr Phe Ser Leu Asp Gly 550 555 560 565 gca gtt gat ctc tcc atg gtg atc aga act ctc gtc atc cag aac aat 1843 Ala Val Asp Leu Ser Met Val Ile Arg Thr Leu Val Ile Gln Asn Asn 570 575 580 cac gtg gag tac gga gtg ggc ggt gca ctt ctt gct ctg tct gat ccg 1891 His Val Glu Tyr Gly Val Gly Gly Ala Leu Leu Ala Leu Ser Asp Pro 585 590 595 gag gct gag tgg gag gaa atc cgc gtt aaa tca cgg cct ctg ctg aat 1939 Glu Ala Glu Trp Glu Glu Ile Arg Val Lys Ser Arg Pro Leu Leu Asn 600 605 610 ttg ttt ggg gtt gaa ttc cca tgacgtacct cgtgtgggac ggt 1983 Leu Phe Gly Val Glu Phe Pro 615 620 <210> 460 <211> 620 <212> PRT <213> Corynebacterium glutamicum <400> 460 Met Arg Val Leu Ile Ile Asp Asn Tyr Asp Ser Phe Thr Phe Asn Leu 1 5 10 15 Ala Thr Tyr Val Glu Glu Val Thr Gly Gln Ala Pro Val Val Val Pro 20 25 30 Asn Asp Gln Glu Ile Asp Glu Met Leu Phe Asp Ala Val Ile Leu Ser 35 40 45 Pro Gly Pro Gly His Ala Gly Val Ala Ala Asp Phe Gly Ile Cys Ala 50 55 60 Gly Val Ile Glu Arg Ala Arg Val Pro Ile Leu Gly Val Cys Leu Gly 65 70 75 80 His Gln Gly Ile Ala Leu Ala Tyr Gly Gly Asp Val Asp Leu Ala Pro 85 90 95 Arg Pro Val His Gly Glu Val Ser Gln Ile Thr His Asp Gly Ser Gly 100 105 110 Leu Phe Ala Gly Ile Pro Glu Thr Phe Glu Ala Val Arg Tyr His Ser 115 120 125 Met Val Ala Thr Arg Leu Pro Glu Ser Leu Lys Ala Thr Ala Thr Ser 130 135 140 Asp Asp Gly Leu Ile Met Ala Leu Ala His Glu Val Leu Pro Gln Trp 145 150 155 160 Gly Val Gln Phe His Pro Glu Ser Ile Gly Gly Gln Phe Gly His Gln 165 170 175 Ile Ile Lys Asn Phe Leu Asn Leu Ala Arg Thr Tyr Arg Trp Gln Leu 180 185 190 Thr Glu Lys Thr Ile Pro Leu Ser Val Asp Ser Ala Ala Val Phe Glu 195 200 205 Thr Phe Phe Ala His Ser Ser His Ala Phe Trp Leu Asp Asp Ala Gln 210 215 220 Gly Thr Ser Tyr Leu Gly Asp Ala Ser Gly Pro Leu Ala Arg Thr Lys 225 230 235 240 Thr His Asn Val Gly Glu Gly Asp Phe Phe Thr Trp Leu Lys Glu Asp 245 250 255 Leu Ala Ala Asn Ser Val Ala Pro Gly Gln Gly Phe Arg Leu Gly Trp 260 265 270 Val Gly Tyr Val Gly Tyr Glu Leu Lys Ala Glu Ala Gly Ala Arg Ala 275 280 285 Ala His Thr Ser Ser Leu Pro Asp Ala His Leu Ile Phe Ala Asp Arg 290 295 300 Ala Ile Ala Val Glu Ser Asp Gln Val Arg Leu Leu Ala Leu Gly Glu 305 310 315 320 Gln Asp Glu Trp Phe Glu Glu Thr Ile Lys Lys Leu His Asn Leu Val 325 330 335 Ala Pro Arg Ile Pro Ala Ser Gly His Leu Ala Leu Gln Val Arg Asp 340 345 350 Ser Lys Asp Glu Tyr Leu Asp Lys Ile Arg Arg Ala Gln Glu Leu Ile 355 360 365 Thr Arg Gly Glu Ser Tyr Glu Ile Cys Leu Thr Thr Lys Leu Gln Gly 370 375 380 Thr Thr Asp Val Ala Pro Leu Ala Ala Tyr Leu Ala Leu Arg Gly Ala 385 390 395 400 Asn Pro Thr Ala Tyr Gly Ala Tyr Leu Gln Leu Gly Asp Thr Ser Ile 405 410 415 Leu Ser Ser Ser Pro Glu Arg Phe Ile Thr Ile Asp Ser Ala Gly Tyr 420 425 430 Val Glu Ser Lys Pro Ile Lys Gly Thr Arg Pro Arg Gly Arg Thr Ala 435 440 445 Gln Glu Asp Gln Glu Ile Ile Ala Glu Leu Arg Ser Asn Pro Lys Asp 450 455 460 Arg Ala Glu Asn Leu Met Ile Val Asp Leu Val Arg Asn Asp Leu Ala 465 470 475 480 Arg Gly Ala Leu Pro Thr Thr Val Lys Thr Ser Lys Leu Phe Asp Val 485 490 495 Glu Thr Tyr Ala Thr Val His Gln Leu Val Ser Thr Val Ser Ala Glu 500 505 510 Leu Gly Pro Arg Ser Pro Ile Glu Cys Val Arg Ala Ala Phe Pro Gly 515 520 525 Gly Ser Met Thr Gly Ala Pro Lys Leu Arg Thr Met Glu Ile Ile Asp 530 535 540 Glu Leu Glu Ala Ala Pro Arg Gly Ile Tyr Ser Gly Gly Leu Gly Tyr 545 550 555 560 Phe Ser Leu Asp Gly Ala Val Asp Leu Ser Met Val Ile Arg Thr Leu 565 570 575 Val Ile Gln Asn Asn His Val Glu Tyr Gly Val Gly Gly Ala Leu Leu 580 585 590 Ala Leu Ser Asp Pro Glu Ala Glu Trp Glu Glu Ile Arg Val Lys Ser 595 600 605 Arg Pro Leu Leu Asn Leu Phe Gly Val Glu Phe Pro 610 615 620 <210> 461 <211> 747 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(724) <223> RXA00958 <400> 461 attctaatcc tcaatctgaa gccgatgaga cgttgcacaa ggcgtatgcc gtgttgaatg 60 ccattgcgct tgctgctggt tccactttgg aggtcatccg atg aca cac gtt gtt 115 Met Thr His Val Val 1 5 ctc att gat aat cac gat tct ttt gtc tac aac ctg gtg gat gcg ttc 163 Leu Ile Asp Asn His Asp Ser Phe Val Tyr Asn Leu Val Asp Ala Phe 10 15 20 gcc gtg gcc ggt tat aag tgc acg gtg ttc cgc aat acg gtg cca gtg 211 Ala Val Ala Gly Tyr Lys Cys Thr Val Phe Arg Asn Thr Val Pro Val 25 30 35 gaa acc att ttg gca gcc aac ccg gac ctg atc tgc ctt tca cct gga 259 Glu Thr Ile Leu Ala Ala Asn Pro Asp Leu Ile Cys Leu Ser Pro Gly 40 45 50 cct ggt tac cct gcc gat gcg ggc aac atg atg gcg ctg atc gag cgc 307 Pro Gly Tyr Pro Ala Asp Ala Gly Asn Met Met Ala Leu Ile Glu Arg 55 60 65 aca ctc ggc cag att cct tta ctg ggt att tgc ctc ggc tac cag gca 355 Thr Leu Gly Gln Ile Pro Leu Leu Gly Ile Cys Leu Gly Tyr Gln Ala 70 75 80 85 ctc atc gaa tac cac ggc ggc aag gtt gag cct tgt ggc cct gtg cac 403 Leu Ile Glu Tyr His Gly Gly Lys Val Glu Pro Cys Gly Pro Val His 90 95 100 ggc acc acc gac aac atg atc ctt act gat gca ggt gtg cag agc cct 451 Gly Thr Thr Asp Asn Met Ile Leu Thr Asp Ala Gly Val Gln Ser Pro 105 110 115 gtt ttt gca ggt ctt gcc act gat gtt gag cct gat cat cca gaa atc 499 Val Phe Ala Gly Leu Ala Thr Asp Val Glu Pro Asp His Pro Glu Ile 120 125 130 cca ggc cgc aag gtt cca att ggc cgt tat cac tca ctg ggc tgc gtg 547 Pro Gly Arg Lys Val Pro Ile Gly Arg Tyr His Ser Leu Gly Cys Val 135 140 145 gtt gcc cca gac ggt att gaa tca cta ggt acc tgt tcc tcg gag att 595 Val Ala Pro Asp Gly Ile Glu Ser Leu Gly Thr Cys Ser Ser Glu Ile 150 155 160 165 ggt gat gtc atc atg gcg gca cgc acc acc gat gga aag gcc att ggc 643 Gly Asp Val Ile Met Ala Ala Arg Thr Thr Asp Gly Lys Ala Ile Gly 170 175 180 ctg cag ttt cac cct gag tca gtg cta agc cca acg ggt cct gtc att 691 Leu Gln Phe His Pro Glu Ser Val Leu Ser Pro Thr Gly Pro Val Ile 185 190 195 ttg tcc cgc tgt gtc gaa cag ctt ctc gcg aac taataaaaaa aggatttgat 744 Leu Ser Arg Cys Val Glu Gln Leu Leu Ala Asn 200 205 tca 747 <210> 462 <211> 208 <212> PRT <213> Corynebacterium glutamicum <400> 462 Met Thr His Val Val Leu Ile Asp Asn His Asp Ser Phe Val Tyr Asn 1 5 10 15 Leu Val Asp Ala Phe Ala Val Ala Gly Tyr Lys Cys Thr Val Phe Arg 20 25 30 Asn Thr Val Pro Val Glu Thr Ile Leu Ala Ala Asn Pro Asp Leu Ile 35 40 45 Cys Leu Ser Pro Gly Pro Gly Tyr Pro Ala Asp Ala Gly Asn Met Met 50 55 60 Ala Leu Ile Glu Arg Thr Leu Gly Gln Ile Pro Leu Leu Gly Ile Cys 65 70 75 80 Leu Gly Tyr Gln Ala Leu Ile Glu Tyr His Gly Gly Lys Val Glu Pro 85 90 95 Cys Gly Pro Val His Gly Thr Thr Asp Asn Met Ile Leu Thr Asp Ala 100 105 110 Gly Val Gln Ser Pro Val Phe Ala Gly Leu Ala Thr Asp Val Glu Pro 115 120 125 Asp His Pro Glu Ile Pro Gly Arg Lys Val Pro Ile Gly Arg Tyr His 130 135 140 Ser Leu Gly Cys Val Val Ala Pro Asp Gly Ile Glu Ser Leu Gly Thr 145 150 155 160 Cys Ser Ser Glu Ile Gly Asp Val Ile Met Ala Ala Arg Thr Thr Asp 165 170 175 Gly Lys Ala Ile Gly Leu Gln Phe His Pro Glu Ser Val Leu Ser Pro 180 185 190 Thr Gly Pro Val Ile Leu Ser Arg Cys Val Glu Gln Leu Leu Ala Asn 195 200 205 <210> 463 <211> 469 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(469) <223> RXN03007 <400> 463 cagtttcacc ctgagtcagt gctaagccca acgggtcctg tcattttgtc ccgctgtgtc 60 gaacagcttc tcgcgaacta ataaaaaaag gatttgattc atg act tct cca gca 115 Met Thr Ser Pro Ala 1 5 aca ctg aaa gtt ctc aac gcc tac ttg gat aac ccc act cca acc ctg 163 Thr Leu Lys Val Leu Asn Ala Tyr Leu Asp Asn Pro Thr Pro Thr Leu 10 15 20 gag gag gca att gag gtg ttc acc ccg ctg acc gtg ggt gaa tac gat 211 Glu Glu Ala Ile Glu Val Phe Thr Pro Leu Thr Val Gly Glu Tyr Asp 25 30 35 gac gtg cac atc gca gcg ctg ctt gcc acc atc cgt act cgc ggt gag 259 Asp Val His Ile Ala Ala Leu Leu Ala Thr Ile Arg Thr Arg Gly Glu 40 45 50 cag ttc gct gat att gcc ggc gct gcc aag gcg ttc ctc gcg gcg gct 307 Gln Phe Ala Asp Ile Ala Gly Ala Ala Lys Ala Phe Leu Ala Ala Ala 55 60 65 cgt ccg ttc ccg att act ggc gca ggt ttg cta gat tcc gct ggt act 355 Arg Pro Phe Pro Ile Thr Gly Ala Gly Leu Leu Asp Ser Ala Gly Thr 70 75 80 85 ggt ggc gac ggt gcc aac acc atc aac atc acc acc ggc gca tcc ctg 403 Gly Gly Asp Gly Ala Asn Thr Ile Asn Ile Thr Thr Gly Ala Ser Leu 90 95 100 atc gca gca tcc ggt gga gtg aag ctg gtt aag cac ggc aac cgt tcg 451 Ile Ala Ala Ser Gly Gly Val Lys Leu Val Lys His Gly Asn Arg Ser 105 110 115 gtg agc tcc aag tcc ggc 469 Val Ser Ser Lys Ser Gly 120 <210> 464 <211> 123 <212> PRT <213> Corynebacterium glutamicum <400> 464 Met Thr Ser Pro Ala Thr Leu Lys Val Leu Asn Ala Tyr Leu Asp Asn 1 5 10 15 Pro Thr Pro Thr Leu Glu Glu Ala Ile Glu Val Phe Thr Pro Leu Thr 20 25 30 Val Gly Glu Tyr Asp Asp Val His Ile Ala Ala Leu Leu Ala Thr Ile 35 40 45 Arg Thr Arg Gly Glu Gln Phe Ala Asp Ile Ala Gly Ala Ala Lys Ala 50 55 60 Phe Leu Ala Ala Ala Arg Pro Phe Pro Ile Thr Gly Ala Gly Leu Leu 65 70 75 80 Asp Ser Ala Gly Thr Gly Gly Asp Gly Ala Asn Thr Ile Asn Ile Thr 85 90 95 Thr Gly Ala Ser Leu Ile Ala Ala Ser Gly Gly Val Lys Leu Val Lys 100 105 110 His Gly Asn Arg Ser Val Ser Ser Lys Ser Gly 115 120 <210> 465 <211> 564 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(541) <223> RXN02918 <400> 465 agattgtcgc ttttcccatt tctccgggtt ttctggaact ttttgggcgt atgctgggaa 60 tgattctatt attgccaaat cagaaagcag gagagacccg atg agc gaa atc cta 115 Met Ser Glu Ile Leu 1 5 gaa acc tat tgg gca ccc cac ttt gga aaa acc gaa gaa gcc aca gca 163 Glu Thr Tyr Trp Ala Pro His Phe Gly Lys Thr Glu Glu Ala Thr Ala 10 15 20 ctc gtt tca tac ctg gca caa gct tcc ggc gat ccc att gag gtt cac 211 Leu Val Ser Tyr Leu Ala Gln Ala Ser Gly Asp Pro Ile Glu Val His 25 30 35 acc ctg ttc ggg gat tta ggt tta gac gga ctc tct gga aac tac acc 259 Thr Leu Phe Gly Asp Leu Gly Leu Asp Gly Leu Ser Gly Asn Tyr Thr 40 45 50 gac act gag att gac ggc tac ggc gac gca ttc ctg ctg gtt gca gcg 307 Asp Thr Glu Ile Asp Gly Tyr Gly Asp Ala Phe Leu Leu Val Ala Ala 55 60 65 cta tcc gtg ttg atg gct gaa aac aaa gca aca ggt ggc gtg aat ctg 355 Leu Ser Val Leu Met Ala Glu Asn Lys Ala Thr Gly Gly Val Asn Leu 70 75 80 85 ggt gag ctt ggg gga gct gat aaa tcg atc cgg ctg cat gtt gaa tcc 403 Gly Glu Leu Gly Gly Ala Asp Lys Ser Ile Arg Leu His Val Glu Ser 90 95 100 aag gag aac acc caa atc aac acc gca ttg aag tat ttt gcg ctc tcc 451 Lys Glu Asn Thr Gln Ile Asn Thr Ala Leu Lys Tyr Phe Ala Leu Ser 105 110 115 cca gaa gac cac gca gca gca gat cgc ttc gat gag gat gac ctg tct 499 Pro Glu Asp His Ala Ala Ala Asp Arg Phe Asp Glu Asp Asp Leu Ser 120 125 130 gag ctt gcc aac ttg agt gaa gag ctg cgc gga cag ctg gac 541 Glu Leu Ala Asn Leu Ser Glu Glu Leu Arg Gly Gln Leu Asp 135 140 145 taattgtctc ccatttaagg agt 564 <210> 466 <211> 147 <212> PRT <213> Corynebacterium glutamicum <400> 466 Met Ser Glu Ile Leu Glu Thr Tyr Trp Ala Pro His Phe Gly Lys Thr 1 5 10 15 Glu Glu Ala Thr Ala Leu Val Ser Tyr Leu Ala Gln Ala Ser Gly Asp 20 25 30 Pro Ile Glu Val His Thr Leu Phe Gly Asp Leu Gly Leu Asp Gly Leu 35 40 45 Ser Gly Asn Tyr Thr Asp Thr Glu Ile Asp Gly Tyr Gly Asp Ala Phe 50 55 60 Leu Leu Val Ala Ala Leu Ser Val Leu Met Ala Glu Asn Lys Ala Thr 65 70 75 80 Gly Gly Val Asn Leu Gly Glu Leu Gly Gly Ala Asp Lys Ser Ile Arg 85 90 95 Leu His Val Glu Ser Lys Glu Asn Thr Gln Ile Asn Thr Ala Leu Lys 100 105 110 Tyr Phe Ala Leu Ser Pro Glu Asp His Ala Ala Ala Asp Arg Phe Asp 115 120 125 Glu Asp Asp Leu Ser Glu Leu Ala Asn Leu Ser Glu Glu Leu Arg Gly 130 135 140 Gln Leu Asp 145 <210> 467 <211> 735 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(712) <223> RXN01116 <400> 467 tgccaggaat ttacgtcaac cgcgtcgtcc acgttggacc gcaggaaacc ggaatcgaaa 60 acaggacggt gtctaactaa tgacttggga tcataaccaa atg gca gcc cgc gtt 115 Met Ala Ala Arg Val 1 5 gcc cag gaa ctt gaa gac ggc cag tac gtc aac ctc ggc atc ggc atg 163 Ala Gln Glu Leu Glu Asp Gly Gln Tyr Val Asn Leu Gly Ile Gly Met 10 15 20 cct aca ctt atc ccc ggc tac ctg cct gag gga cta gag gtt atc ctt 211 Pro Thr Leu Ile Pro Gly Tyr Leu Pro Glu Gly Leu Glu Val Ile Leu 25 30 35 cac tcc gaa aac ggt gtg ctg ggc gtt gga cct tac cca act gaa gag 259 His Ser Glu Asn Gly Val Leu Gly Val Gly Pro Tyr Pro Thr Glu Glu 40 45 50 gaa ctt gat cct gag ctg atc aac gcc ggc aag gaa acc atc acg gtt 307 Glu Leu Asp Pro Glu Leu Ile Asn Ala Gly Lys Glu Thr Ile Thr Val 55 60 65 gca cct ggc gca tcc tac ttc tcc tct tct gat tct ttc gcc atg atc 355 Ala Pro Gly Ala Ser Tyr Phe Ser Ser Ser Asp Ser Phe Ala Met Ile 70 75 80 85 cgc tcc aag tct gtc gac gtt gca gtc ttg ggc gtt atg gaa gtc tcc 403 Arg Ser Lys Ser Val Asp Val Ala Val Leu Gly Val Met Glu Val Ser 90 95 100 cag tac ggc gac ctg gcc aac tgg atg att ccc ggc aag ctg gtc aag 451 Gln Tyr Gly Asp Leu Ala Asn Trp Met Ile Pro Gly Lys Leu Val Lys 105 110 115 ggt atg ggt ggc gca atg gat ctg gtg cac ggc gca tcc aag atc atc 499 Gly Met Gly Gly Ala Met Asp Leu Val His Gly Ala Ser Lys Ile Ile 120 125 130 gcc atg acc gat cac atc acc aag aag ggc gct ccg aag atc ctt aag 547 Ala Met Thr Asp His Ile Thr Lys Lys Gly Ala Pro Lys Ile Leu Lys 135 140 145 gag tgt cgc ctc cca ctg act ggc gcg aag tgc gtg gac atg att gtc 595 Glu Cys Arg Leu Pro Leu Thr Gly Ala Lys Cys Val Asp Met Ile Val 150 155 160 165 acc acc cac gct gtg ttc tct gtg gac cct gaa gaa ggc ctc acg ctc 643 Thr Thr His Ala Val Phe Ser Val Asp Pro Glu Glu Gly Leu Thr Leu 170 175 180 atc gag tgc gcc gac ggt gtc acc gtt gag gaa ctc cgc gaa atc acc 691 Ile Glu Cys Ala Asp Gly Val Thr Val Glu Glu Leu Arg Glu Ile Thr 185 190 195 gaa gcc gat ttc aaa gtt gct taagcaaacg ctgcgcaatt aag 735 Glu Ala Asp Phe Lys Val Ala 200 <210> 468 <211> 204 <212> PRT <213> Corynebacterium glutamicum <400> 468 Met Ala Ala Arg Val Ala Gln Glu Leu Glu Asp Gly Gln Tyr Val Asn 1 5 10 15 Leu Gly Ile Gly Met Pro Thr Leu Ile Pro Gly Tyr Leu Pro Glu Gly 20 25 30 Leu Glu Val Ile Leu His Ser Glu Asn Gly Val Leu Gly Val Gly Pro 35 40 45 Tyr Pro Thr Glu Glu Glu Leu Asp Pro Glu Leu Ile Asn Ala Gly Lys 50 55 60 Glu Thr Ile Thr Val Ala Pro Gly Ala Ser Tyr Phe Ser Ser Ser Asp 65 70 75 80 Ser Phe Ala Met Ile Arg Ser Lys Ser Val Asp Val Ala Val Leu Gly 85 90 95 Val Met Glu Val Ser Gln Tyr Gly Asp Leu Ala Asn Trp Met Ile Pro 100 105 110 Gly Lys Leu Val Lys Gly Met Gly Gly Ala Met Asp Leu Val His Gly 115 120 125 Ala Ser Lys Ile Ile Ala Met Thr Asp His Ile Thr Lys Lys Gly Ala 130 135 140 Pro Lys Ile Leu Lys Glu Cys Arg Leu Pro Leu Thr Gly Ala Lys Cys 145 150 155 160 Val Asp Met Ile Val Thr Thr His Ala Val Phe Ser Val Asp Pro Glu 165 170 175 Glu Gly Leu Thr Leu Ile Glu Cys Ala Asp Gly Val Thr Val Glu Glu 180 185 190 Leu Arg Glu Ile Thr Glu Ala Asp Phe Lys Val Ala 195 200 <210> 469 <211> 876 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(853) <223> RXN01115 <400> 469 ctcaccgcat gcagcgtgaa aacactcagt acggactggc caccatgtgc atcggtggcg 60 gccagggtct tgcagctgtc tttgaaaagg agaactaaaa atg gct att ttg cac 115 Met Ala Ile Leu His 1 5 agc gtt tcc tac gga act tcc gac aac acc ttg gtg ttc att ggc tcg 163 Ser Val Ser Tyr Gly Thr Ser Asp Asn Thr Leu Val Phe Ile Gly Ser 10 15 20 ttg ggt tcc acc acc gac atg tgg ctg cca cag ctg gat gcc ttg cat 211 Leu Gly Ser Thr Thr Asp Met Trp Leu Pro Gln Leu Asp Ala Leu His 25 30 35 aag gat ttc cgc gtc atc gct gtt gat cac cgc gga cat ggt ctg tct 259 Lys Asp Phe Arg Val Ile Ala Val Asp His Arg Gly His Gly Leu Ser 40 45 50 gaa ctc atc gaa ggc acc ccc act gtg gcg gat ctg gcg cag gat gtg 307 Glu Leu Ile Glu Gly Thr Pro Thr Val Ala Asp Leu Ala Gln Asp Val 55 60 65 ctg gat acc ctc gat gac ctg ggt gtc gga aac ttc ggc gtc atc gga 355 Leu Asp Thr Leu Asp Asp Leu Gly Val Gly Asn Phe Gly Val Ile Gly 70 75 80 85 cta tct ctc ggc gga gcg gtt gca caa tac ttg gcg gcc acc tct gat 403 Leu Ser Leu Gly Gly Ala Val Ala Gln Tyr Leu Ala Ala Thr Ser Asp 90 95 100 cgt gtc acc aag gca gca ttc atg tgt acc gct gca aaa ttc ggc gag 451 Arg Val Thr Lys Ala Ala Phe Met Cys Thr Ala Ala Lys Phe Gly Glu 105 110 115 ccc cag ggc tgg cta gat cgc gcc gca gcg tgc cgc gaa aac ggc act 499 Pro Gln Gly Trp Leu Asp Arg Ala Ala Ala Cys Arg Glu Asn Gly Thr 120 125 130 ggt tct ctg tcc gaa gct gtg atc cag cgc tgg ttc tcc ccc act tgg 547 Gly Ser Leu Ser Glu Ala Val Ile Gln Arg Trp Phe Ser Pro Thr Trp 135 140 145 ttg gag aac aac cca gcg tcc cgc gag cac ttc gaa gcc atg gtt gcc 595 Leu Glu Asn Asn Pro Ala Ser Arg Glu His Phe Glu Ala Met Val Ala 150 155 160 165 ggc acc cca tct gag ggt tac gcg ctg tgc tgc gag gcg ttg gca acc 643 Gly Thr Pro Ser Glu Gly Tyr Ala Leu Cys Cys Glu Ala Leu Ala Thr 170 175 180 tgg gat ttc acc gat cgc ctg gga gaa atc acc gtg cca gtg ctc acc 691 Trp Asp Phe Thr Asp Arg Leu Gly Glu Ile Thr Val Pro Val Leu Thr 185 190 195 atc gca ggt gcc gat gac ccc tcc act cct cca gca acc gtg cag atc 739 Ile Ala Gly Ala Asp Asp Pro Ser Thr Pro Pro Ala Thr Val Gln Ile 200 205 210 att gcc gat ggc gtt ggc ggc gag tcc cgc gca gag gtc cta agc cca 787 Ile Ala Asp Gly Val Gly Gly Glu Ser Arg Ala Glu Val Leu Ser Pro 215 220 225 gcc gcg cac gta cca acc gtg gaa cgt cca aac gag gta aat gaa ctg 835 Ala Ala His Val Pro Thr Val Glu Arg Pro Asn Glu Val Asn Glu Leu 230 235 240 245 cta gca cag cat ttc gct taatgttgta ggcatgttca caa 876 Leu Ala Gln His Phe Ala 250 <210> 470 <211> 251 <212> PRT <213> Corynebacterium glutamicum <400> 470 Met Ala Ile Leu His Ser Val Ser Tyr Gly Thr Ser Asp Asn Thr Leu 1 5 10 15 Val Phe Ile Gly Ser Leu Gly Ser Thr Thr Asp Met Trp Leu Pro Gln 20 25 30 Leu Asp Ala Leu His Lys Asp Phe Arg Val Ile Ala Val Asp His Arg 35 40 45 Gly His Gly Leu Ser Glu Leu Ile Glu Gly Thr Pro Thr Val Ala Asp 50 55 60 Leu Ala Gln Asp Val Leu Asp Thr Leu Asp Asp Leu Gly Val Gly Asn 65 70 75 80 Phe Gly Val Ile Gly Leu Ser Leu Gly Gly Ala Val Ala Gln Tyr Leu 85 90 95 Ala Ala Thr Ser Asp Arg Val Thr Lys Ala Ala Phe Met Cys Thr Ala 100 105 110 Ala Lys Phe Gly Glu Pro Gln Gly Trp Leu Asp Arg Ala Ala Ala Cys 115 120 125 Arg Glu Asn Gly Thr Gly Ser Leu Ser Glu Ala Val Ile Gln Arg Trp 130 135 140 Phe Ser Pro Thr Trp Leu Glu Asn Asn Pro Ala Ser Arg Glu His Phe 145 150 155 160 Glu Ala Met Val Ala Gly Thr Pro Ser Glu Gly Tyr Ala Leu Cys Cys 165 170 175 Glu Ala Leu Ala Thr Trp Asp Phe Thr Asp Arg Leu Gly Glu Ile Thr 180 185 190 Val Pro Val Leu Thr Ile Ala Gly Ala Asp Asp Pro Ser Thr Pro Pro 195 200 205 Ala Thr Val Gln Ile Ile Ala Asp Gly Val Gly Gly Glu Ser Arg Ala 210 215 220 Glu Val Leu Ser Pro Ala Ala His Val Pro Thr Val Glu Arg Pro Asn 225 230 235 240 Glu Val Asn Glu Leu Leu Ala Gln His Phe Ala 245 250 <210> 471 <211> 1284 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1261) <223> RXS00116 <400> 471 cgcggcacgc acgctggggg caagcgtcga caagcacaaa ctttttgctt aattgaatcc 60 tttgcgcacc aatcaatggg ggatcaaata tagtagctgc atg agt aat gac ttc 115 Met Ser Asn Asp Phe 1 5 gtc gtt tct agg ctt aga ccc ttt ggt gaa acg att ttt gca acc atg 163 Val Val Ser Arg Leu Arg Pro Phe Gly Glu Thr Ile Phe Ala Thr Met 10 15 20 acc cag cga gct gtt gag gcg ggt gca atc aat ctt ggt cag ggc ttt 211 Thr Gln Arg Ala Val Glu Ala Gly Ala Ile Asn Leu Gly Gln Gly Phe 25 30 35 cct gat gag gat ggt cct cgt cgg atg tta gag atc gcg tcg gag cag 259 Pro Asp Glu Asp Gly Pro Arg Arg Met Leu Glu Ile Ala Ser Glu Gln 40 45 50 att ctc ggg gga aat aat cag tat tcg gcg ggg cgt ggg gat gct tcg 307 Ile Leu Gly Gly Asn Asn Gln Tyr Ser Ala Gly Arg Gly Asp Ala Ser 55 60 65 ttg agg gca gct gtg gct cgt gat cat ttg gag agg ttt gat ctg gag 355 Leu Arg Ala Ala Val Ala Arg Asp His Leu Glu Arg Phe Asp Leu Glu 70 75 80 85 tac aac cct gat tcg gag gtg ttg atc acg gtg ggg gcc act gag gcg 403 Tyr Asn Pro Asp Ser Glu Val Leu Ile Thr Val Gly Ala Thr Glu Ala 90 95 100 att acg gcg act gtg ttg ggt ttg gtg gag cct ggg gat gaa gtg atc 451 Ile Thr Ala Thr Val Leu Gly Leu Val Glu Pro Gly Asp Glu Val Ile 105 110 115 gtt ttg gaa ccg tat tac gat gcg tat gcg gcg gct att gcg ttg gcg 499 Val Leu Glu Pro Tyr Tyr Asp Ala Tyr Ala Ala Ala Ile Ala Leu Ala 120 125 130 ggg gcg acg cgg gtg gcg gtt cct ttg cag gag gtg gag aac tcg tgg 547 Gly Ala Thr Arg Val Ala Val Pro Leu Gln Glu Val Glu Asn Ser Trp 135 140 145 gat gtg gat gtc gat aag ttg cat gcg gcg gtg act aag aag acg cgg 595 Asp Val Asp Val Asp Lys Leu His Ala Ala Val Thr Lys Lys Thr Arg 150 155 160 165 atg att atc gtt aat tcg ccg cat aat ccg acg ggt tcg gtg ttt tct 643 Met Ile Ile Val Asn Ser Pro His Asn Pro Thr Gly Ser Val Phe Ser 170 175 180 aag aag gcg ttg aag cag ttg gcg ggt gtt gct cgt gcg tat gac ttg 691 Lys Lys Ala Leu Lys Gln Leu Ala Gly Val Ala Arg Ala Tyr Asp Leu 185 190 195 ttg gtg ttg tca gat gag gtg tat gag cat ctt gtt ttt gat gat cag 739 Leu Val Leu Ser Asp Glu Val Tyr Glu His Leu Val Phe Asp Asp Gln 200 205 210 aag cat gtg agt gtc gcg aag ctg ccc ggt atg tgg gat cgc acg gtg 787 Lys His Val Ser Val Ala Lys Leu Pro Gly Met Trp Asp Arg Thr Val 215 220 225 acg gtg tcg tcg gcg gcg aaa acg ttc aat gtg act ggt tgg aag acg 835 Thr Val Ser Ser Ala Ala Lys Thr Phe Asn Val Thr Gly Trp Lys Thr 230 235 240 245 ggg tgg gcg ttg gca ccg gag ccg ttg ttg gag gcg gtg ttg aag gcg 883 Gly Trp Ala Leu Ala Pro Glu Pro Leu Leu Glu Ala Val Leu Lys Ala 250 255 260 aag cag ttt atg tct tat gtg ggg gct aca cct ttt cag ccg gct gtg 931 Lys Gln Phe Met Ser Tyr Val Gly Ala Thr Pro Phe Gln Pro Ala Val 265 270 275 gcg cat gcg att gaa cat gag cag aag tgg gtg tca aag atg tct aag 979 Ala His Ala Ile Glu His Glu Gln Lys Trp Val Ser Lys Met Ser Lys 280 285 290 ggg ctt gag ctc aag cgg gat att ttg cgt act gcg tta gat aag gcg 1027 Gly Leu Glu Leu Lys Arg Asp Ile Leu Arg Thr Ala Leu Asp Lys Ala 295 300 305 ggg ctg aag act cat gac agt atg ggc acg tat ttc atc gtt gcg gat 1075 Gly Leu Lys Thr His Asp Ser Met Gly Thr Tyr Phe Ile Val Ala Asp 310 315 320 325 att ggg gat cgt gat ggt gcg gag ttc tgt ttt gag ttg att gag aag 1123 Ile Gly Asp Arg Asp Gly Ala Glu Phe Cys Phe Glu Leu Ile Glu Lys 330 335 340 gtt ggg gtg gcg gcg att ccg gtg cag gcg ttt gtg gat cat ccg aag 1171 Val Gly Val Ala Ala Ile Pro Val Gln Ala Phe Val Asp His Pro Lys 345 350 355 aag tgg tcg tcg aag gtt cgt ttt gcg ttt tgc aaa aaa gaa gag acg 1219 Lys Trp Ser Ser Lys Val Arg Phe Ala Phe Cys Lys Lys Glu Glu Thr 360 365 370 ctc cgc gaa gct gcg gag cgt ctc aag ggg att aag aaa cta 1261 Leu Arg Glu Ala Ala Glu Arg Leu Lys Gly Ile Lys Lys Leu 375 380 385 tagtttgaac aggttgttgg ggg 1284 <210> 472 <211> 387 <212> PRT <213> Corynebacterium glutamicum <400> 472 Met Ser Asn Asp Phe Val Val Ser Arg Leu Arg Pro Phe Gly Glu Thr 1 5 10 15 Ile Phe Ala Thr Met Thr Gln Arg Ala Val Glu Ala Gly Ala Ile Asn 20 25 30 Leu Gly Gln Gly Phe Pro Asp Glu Asp Gly Pro Arg Arg Met Leu Glu 35 40 45 Ile Ala Ser Glu Gln Ile Leu Gly Gly Asn Asn Gln Tyr Ser Ala Gly 50 55 60 Arg Gly Asp Ala Ser Leu Arg Ala Ala Val Ala Arg Asp His Leu Glu 65 70 75 80 Arg Phe Asp Leu Glu Tyr Asn Pro Asp Ser Glu Val Leu Ile Thr Val 85 90 95 Gly Ala Thr Glu Ala Ile Thr Ala Thr Val Leu Gly Leu Val Glu Pro 100 105 110 Gly Asp Glu Val Ile Val Leu Glu Pro Tyr Tyr Asp Ala Tyr Ala Ala 115 120 125 Ala Ile Ala Leu Ala Gly Ala Thr Arg Val Ala Val Pro Leu Gln Glu 130 135 140 Val Glu Asn Ser Trp Asp Val Asp Val Asp Lys Leu His Ala Ala Val 145 150 155 160 Thr Lys Lys Thr Arg Met Ile Ile Val Asn Ser Pro His Asn Pro Thr 165 170 175 Gly Ser Val Phe Ser Lys Lys Ala Leu Lys Gln Leu Ala Gly Val Ala 180 185 190 Arg Ala Tyr Asp Leu Leu Val Leu Ser Asp Glu Val Tyr Glu His Leu 195 200 205 Val Phe Asp Asp Gln Lys His Val Ser Val Ala Lys Leu Pro Gly Met 210 215 220 Trp Asp Arg Thr Val Thr Val Ser Ser Ala Ala Lys Thr Phe Asn Val 225 230 235 240 Thr Gly Trp Lys Thr Gly Trp Ala Leu Ala Pro Glu Pro Leu Leu Glu 245 250 255 Ala Val Leu Lys Ala Lys Gln Phe Met Ser Tyr Val Gly Ala Thr Pro 260 265 270 Phe Gln Pro Ala Val Ala His Ala Ile Glu His Glu Gln Lys Trp Val 275 280 285 Ser Lys Met Ser Lys Gly Leu Glu Leu Lys Arg Asp Ile Leu Arg Thr 290 295 300 Ala Leu Asp Lys Ala Gly Leu Lys Thr His Asp Ser Met Gly Thr Tyr 305 310 315 320 Phe Ile Val Ala Asp Ile Gly Asp Arg Asp Gly Ala Glu Phe Cys Phe 325 330 335 Glu Leu Ile Glu Lys Val Gly Val Ala Ala Ile Pro Val Gln Ala Phe 340 345 350 Val Asp His Pro Lys Lys Trp Ser Ser Lys Val Arg Phe Ala Phe Cys 355 360 365 Lys Lys Glu Glu Thr Leu Arg Glu Ala Ala Glu Arg Leu Lys Gly Ile 370 375 380 Lys Lys Leu 385 <210> 473 <211> 607 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(607) <223> FRXA00116 <400> 473 tttgcgcacc aatcaatggg ggatcaaata tagtagctgc atgagtaatg acttcgtcgt 60 ttctaggctt agaccctttg gtgaaacgat ttttgcaacc atg acc cag cga gct 115 Met Thr Gln Arg Ala 1 5 gtt gag gcg ggt gca atc aat ctt ggt cag ggc ttt cct gat gag gat 163 Val Glu Ala Gly Ala Ile Asn Leu Gly Gln Gly Phe Pro Asp Glu Asp 10 15 20 ggt cct cgt cgg atg tta gag atc gcg tcg gag cag att ctc ggg gga 211 Gly Pro Arg Arg Met Leu Glu Ile Ala Ser Glu Gln Ile Leu Gly Gly 25 30 35 aat aat cag tat tcg gcg ggg cgt ggg gat gct tcg ttg agg gca gct 259 Asn Asn Gln Tyr Ser Ala Gly Arg Gly Asp Ala Ser Leu Arg Ala Ala 40 45 50 gtg gct cgt gat cat ttg gag agg ttt gat ctg gag tac aac cct gat 307 Val Ala Arg Asp His Leu Glu Arg Phe Asp Leu Glu Tyr Asn Pro Asp 55 60 65 tcg gag gtg ttg atc acg gtg ggg gcc act gag gcg att acg gcg act 355 Ser Glu Val Leu Ile Thr Val Gly Ala Thr Glu Ala Ile Thr Ala Thr 70 75 80 85 gtg ttg ggt ttg gtg gag cct ggg gat gaa gtg atc gtt ttg gaa ccg 403 Val Leu Gly Leu Val Glu Pro Gly Asp Glu Val Ile Val Leu Glu Pro 90 95 100 tat tac gat gcg tat gcg gcg gct att gcg ttg gcg ggg gcg acg cgg 451 Tyr Tyr Asp Ala Tyr Ala Ala Ala Ile Ala Leu Ala Gly Ala Thr Arg 105 110 115 gtg gcg gtt cct ttg cag gag gtg gag aac tcg tgg gat gtg gat gtc 499 Val Ala Val Pro Leu Gln Glu Val Glu Asn Ser Trp Asp Val Asp Val 120 125 130 gat aag ttg cat gcg gcg gtg act aag aag acg cgg atg att atc gtt 547 Asp Lys Leu His Ala Ala Val Thr Lys Lys Thr Arg Met Ile Ile Val 135 140 145 aat tcg ccg cat aat ccg acg ggt tcg gtg ttt tct aag aag gcg ttg 595 Asn Ser Pro His Asn Pro Thr Gly Ser Val Phe Ser Lys Lys Ala Leu 150 155 160 165 aag cag ttg gcg 607 Lys Gln Leu Ala <210> 474 <211> 169 <212> PRT <213> Corynebacterium glutamicum <400> 474 Met Thr Gln Arg Ala Val Glu Ala Gly Ala Ile Asn Leu Gly Gln Gly 1 5 10 15 Phe Pro Asp Glu Asp Gly Pro Arg Arg Met Leu Glu Ile Ala Ser Glu 20 25 30 Gln Ile Leu Gly Gly Asn Asn Gln Tyr Ser Ala Gly Arg Gly Asp Ala 35 40 45 Ser Leu Arg Ala Ala Val Ala Arg Asp His Leu Glu Arg Phe Asp Leu 50 55 60 Glu Tyr Asn Pro Asp Ser Glu Val Leu Ile Thr Val Gly Ala Thr Glu 65 70 75 80 Ala Ile Thr Ala Thr Val Leu Gly Leu Val Glu Pro Gly Asp Glu Val 85 90 95 Ile Val Leu Glu Pro Tyr Tyr Asp Ala Tyr Ala Ala Ala Ile Ala Leu 100 105 110 Ala Gly Ala Thr Arg Val Ala Val Pro Leu Gln Glu Val Glu Asn Ser 115 120 125 Trp Asp Val Asp Val Asp Lys Leu His Ala Ala Val Thr Lys Lys Thr 130 135 140 Arg Met Ile Ile Val Asn Ser Pro His Asn Pro Thr Gly Ser Val Phe 145 150 155 160 Ser Lys Lys Ala Leu Lys Gln Leu Ala 165 <210> 475 <211> 843 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(820) <223> RXS00391 <400> 475 atcttgtaga tcccaccgca attctgggag atctcgagga cgcaatctct ggaagaaaac 60 tttcctcccc atccctgtac aagataaaac ccgtgcacag ttg ctg cgc gat tct 115 Leu Leu Arg Asp Ser 1 5 caa cga gtt ggc ctc gcc atc gat cct tcg atc gct ttg gtg atg gcc 163 Gln Arg Val Gly Leu Ala Ile Asp Pro Ser Ile Ala Leu Val Met Ala 10 15 20 act tct ggt tct aca ggt acc ccg aag ggc gct cag ctc act ccg ttg 211 Thr Ser Gly Ser Thr Gly Thr Pro Lys Gly Ala Gln Leu Thr Pro Leu 25 30 35 aat ttg gtg agt tcc gcc gat gct acg cat cag ttt tta ggt ggc gaa 259 Asn Leu Val Ser Ser Ala Asp Ala Thr His Gln Phe Leu Gly Gly Glu 40 45 50 ggc cag tgg ttg ctt gcc atg cca gca cac cac att gca ggc atg cag 307 Gly Gln Trp Leu Leu Ala Met Pro Ala His His Ile Ala Gly Met Gln 55 60 65 gtg ctt ctt cga agc ctc att gct gga gtt gag cca cta gct att gat 355 Val Leu Leu Arg Ser Leu Ile Ala Gly Val Glu Pro Leu Ala Ile Asp 70 75 80 85 ctc agc aca ggt ttt cac att gac gct ttc gca ggc gcc gcg gca gaa 403 Leu Ser Thr Gly Phe His Ile Asp Ala Phe Ala Gly Ala Ala Ala Glu 90 95 100 ctg aaa aat acc ggc gac cgc gtc tat aca tcc ttg act cca atg cag 451 Leu Lys Asn Thr Gly Asp Arg Val Tyr Thr Ser Leu Thr Pro Met Gln 105 110 115 tta ctt aaa gca atg gac tcc ttg caa ggc att gaa gcc ctg aaa ctt 499 Leu Leu Lys Ala Met Asp Ser Leu Gln Gly Ile Glu Ala Leu Lys Leu 120 125 130 ttt gat gtc att ctt gtt ggc ggt gct gca ttg tct aag cag gcc cga 547 Phe Asp Val Ile Leu Val Gly Gly Ala Ala Leu Ser Lys Gln Ala Arg 135 140 145 att tct gcg gag cag cta gac atc aac att gtc acc acc tac ggc tcc 595 Ile Ser Ala Glu Gln Leu Asp Ile Asn Ile Val Thr Thr Tyr Gly Ser 150 155 160 165 tca gag act tca ggt ggc tgc gtt tat gat ggc aag ccc att ccc ggc 643 Ser Glu Thr Ser Gly Gly Cys Val Tyr Asp Gly Lys Pro Ile Pro Gly 170 175 180 gcg aaa gtc cgt att tcg gat gag cgc att gag ttg ggt ggc ccg atg 691 Ala Lys Val Arg Ile Ser Asp Glu Arg Ile Glu Leu Gly Gly Pro Met 185 190 195 att gcg cag ggc tac aga aat gca cct gaa cat ccg gat ttc gcc aac 739 Ile Ala Gln Gly Tyr Arg Asn Ala Pro Glu His Pro Asp Phe Ala Asn 200 205 210 gag ggt tgg ttt acc acc tct gat tca ggt gaa ctc cac gac ggg att 787 Glu Gly Trp Phe Thr Thr Ser Asp Ser Gly Glu Leu His Asp Gly Ile 215 220 225 ctc acc gtg act ggt cgc gtg gat acc cgt cat tgattccggt ggattgaagt 840 Leu Thr Val Thr Gly Arg Val Asp Thr Arg His 230 235 240 tgc 843 <210> 476 <211> 240 <212> PRT <213> Corynebacterium glutamicum <400> 476 Leu Leu Arg Asp Ser Gln Arg Val Gly Leu Ala Ile Asp Pro Ser Ile 1 5 10 15 Ala Leu Val Met Ala Thr Ser Gly Ser Thr Gly Thr Pro Lys Gly Ala 20 25 30 Gln Leu Thr Pro Leu Asn Leu Val Ser Ser Ala Asp Ala Thr His Gln 35 40 45 Phe Leu Gly Gly Glu Gly Gln Trp Leu Leu Ala Met Pro Ala His His 50 55 60 Ile Ala Gly Met Gln Val Leu Leu Arg Ser Leu Ile Ala Gly Val Glu 65 70 75 80 Pro Leu Ala Ile Asp Leu Ser Thr Gly Phe His Ile Asp Ala Phe Ala 85 90 95 Gly Ala Ala Ala Glu Leu Lys Asn Thr Gly Asp Arg Val Tyr Thr Ser 100 105 110 Leu Thr Pro Met Gln Leu Leu Lys Ala Met Asp Ser Leu Gln Gly Ile 115 120 125 Glu Ala Leu Lys Leu Phe Asp Val Ile Leu Val Gly Gly Ala Ala Leu 130 135 140 Ser Lys Gln Ala Arg Ile Ser Ala Glu Gln Leu Asp Ile Asn Ile Val 145 150 155 160 Thr Thr Tyr Gly Ser Ser Glu Thr Ser Gly Gly Cys Val Tyr Asp Gly 165 170 175 Lys Pro Ile Pro Gly Ala Lys Val Arg Ile Ser Asp Glu Arg Ile Glu 180 185 190 Leu Gly Gly Pro Met Ile Ala Gln Gly Tyr Arg Asn Ala Pro Glu His 195 200 205 Pro Asp Phe Ala Asn Glu Gly Trp Phe Thr Thr Ser Asp Ser Gly Glu 210 215 220 Leu His Asp Gly Ile Leu Thr Val Thr Gly Arg Val Asp Thr Arg His 225 230 235 240 <210> 477 <211> 1017 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(994) <223> RXS00393 <400> 477 tctattcatt tcacaatagc gtttcacact cccccatagc ctgccgaacg tatttcaagc 60 aattgcgcga tcgagtatgt gatggggaaa gatagaggtt atg tct cac acg gaa 115 Met Ser His Thr Glu 1 5 ccc cag ccg aat tct gta act ttg tcc gat tgg att caa ggc gca cgc 163 Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp Ile Gln Gly Ala Arg 10 15 20 ccg cgt acc tgg gca aat gcg ttc gcg cct gtc att gcc ggt tca ggt 211 Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val Ile Ala Gly Ser Gly 25 30 35 gtc gcc gct ttt cat gat ggt ttt gtg tgg tgg aag gcc ttg ctg gcg 259 Val Ala Ala Phe His Asp Gly Phe Val Trp Trp Lys Ala Leu Leu Ala 40 45 50 ctt gtc gtg gcg tgg gct ttg atc atc ggt gtg aat tac gcc aat gat 307 Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val Asn Tyr Ala Asn Asp 55 60 65 tac tct gat ggc att cgt ggc acc gat gaa gac cgc acc ggt cct ctg 355 Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp Arg Thr Gly Pro Leu 70 75 80 85 cga ctc act ggt tct ggg ttg gct gag ccg aag aaa gtg aaa gct gcg 403 Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys Lys Val Lys Ala Ala 90 95 100 gcg ttt att tct ttc ggt atc gca ggt gtc gcc ggc acc gcg ctg agc 451 Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala Gly Thr Ala Leu Ser 105 110 115 ctg ttg agc gcg tgg tgg ctg atc ctc atc ggc atc ctg tgt gtg ctg 499 Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly Ile Leu Cys Val Leu 120 125 130 ggc gcg tgg ttc tac acc ggc ggt aaa aat cct tat ggt tac cgc ggg 547 Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro Tyr Gly Tyr Arg Gly 135 140 145 ctc ggc gag att gct gtg ttc atc ttc ttc ggc ctc gtc gcg gtc atg 595 Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly Leu Val Ala Val Met 150 155 160 165 gga acg cag ttc acc caa acc ggt tcc gtc agc tgg gcc ggt ttg gcc 643 Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser Trp Ala Gly Leu Ala 170 175 180 gcc gca gtt ggc gtg ggg tcg atg tct gct ggc gtg aac ttg gcc aac 691 Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly Val Asn Leu Ala Asn 185 190 195 aat att cgc gat att cca acc gat agc aag acc gga aaa att acc ctc 739 Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr Gly Lys Ile Thr Leu 200 205 210 gcg gtc cgc ctg ggc gat gcg ggt gct cgt aag ctg ttc ctc gcg ctg 787 Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys Leu Phe Leu Ala Leu 215 220 225 att tcc acg ccg ttc atc atg tcc atc tgc ctg gcg ttt gtc gcc tgg 835 Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu Ala Phe Val Ala Trp 230 235 240 245 cca gcg ctg atc gcg atc atc gtt ttc ccg ctg gca ctg aaa gcc gca 883 Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu Ala Leu Lys Ala Ala 250 255 260 ggg ccg atc cgc aac aac gcc acc ggc aag gat ctc atc ccc gtc atc 931 Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp Leu Ile Pro Val Ile 265 270 275 ggc tca aca ggg cgc gcc atg gcg ttg tgg gcc gtg ctc acg ggc ctg 979 Gly Ser Thr Gly Arg Ala Met Ala Leu Trp Ala Val Leu Thr Gly Leu 280 285 290 gca tta gcg ttt agc taaaacgctt ttcgacgctc ccc 1017 Ala Leu Ala Phe Ser 295 <210> 478 <211> 298 <212> PRT <213> Corynebacterium glutamicum <400> 478 Met Ser His Thr Glu Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp 1 5 10 15 Ile Gln Gly Ala Arg Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val 20 25 30 Ile Ala Gly Ser Gly Val Ala Ala Phe His Asp Gly Phe Val Trp Trp 35 40 45 Lys Ala Leu Leu Ala Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val 50 55 60 Asn Tyr Ala Asn Asp Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp 65 70 75 80 Arg Thr Gly Pro Leu Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys 85 90 95 Lys Val Lys Ala Ala Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala 100 105 110 Gly Thr Ala Leu Ser Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly 115 120 125 Ile Leu Cys Val Leu Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro 130 135 140 Tyr Gly Tyr Arg Gly Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly 145 150 155 160 Leu Val Ala Val Met Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser 165 170 175 Trp Ala Gly Leu Ala Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly 180 185 190 Val Asn Leu Ala Asn Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr 195 200 205 Gly Lys Ile Thr Leu Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys 210 215 220 Leu Phe Leu Ala Leu Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu 225 230 235 240 Ala Phe Val Ala Trp Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu 245 250 255 Ala Leu Lys Ala Ala Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp 260 265 270 Leu Ile Pro Val Ile Gly Ser Thr Gly Arg Ala Met Ala Leu Trp Ala 275 280 285 Val Leu Thr Gly Leu Ala Leu Ala Phe Ser 290 295 <210> 479 <211> 1005 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(982) <223> FRXA00393 <400> 479 tctattcatt tcacaatagc gtttcacact cccccatagc ctgccgaacg tatttcaagc 60 aattgcgcga tcgagtatgt gatggggaaa gatagaggtt atg tct cac acg gaa 115 Met Ser His Thr Glu 1 5 ccc cag ccg aat tct gta act ttg tcc gat tgg att caa ggc gca cgc 163 Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp Ile Gln Gly Ala Arg 10 15 20 ccg cgt acc tgg gca aat gcg ttc gcg cct gtc att gcc ggt tca ggt 211 Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val Ile Ala Gly Ser Gly 25 30 35 gtc gcc gct ttt cat gat ggt ttt gtg tgg tgg aag gcc ttg ctg gcg 259 Val Ala Ala Phe His Asp Gly Phe Val Trp Trp Lys Ala Leu Leu Ala 40 45 50 ctt gtc gtg gcg tgg gct ttg atc atc ggt gtg aat tac gcc aat gat 307 Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val Asn Tyr Ala Asn Asp 55 60 65 tac tct gat ggc att cgt ggc acc gat gaa gac cgc acc ggt cct ctg 355 Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp Arg Thr Gly Pro Leu 70 75 80 85 cga ctc act ggt tct ggg ttg gct gag ccg aag aaa gtg aaa gct gcg 403 Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys Lys Val Lys Ala Ala 90 95 100 gcg ttt att tct ttc ggt atc gca ggt gtc gcc ggc acc gcg ctg agc 451 Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala Gly Thr Ala Leu Ser 105 110 115 ctg ttg agc gcg tgg tgg ctg atc ctc atc ggc atc ctg tgt gtg ctg 499 Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly Ile Leu Cys Val Leu 120 125 130 ggc gcg tgg ttc tac acc ggc ggt aaa aat cct tat ggt tac cgc ggg 547 Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro Tyr Gly Tyr Arg Gly 135 140 145 ctc ggc gag att gct gtg ttc atc ttc ttc ggc ctc gtc gcg gtc atg 595 Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly Leu Val Ala Val Met 150 155 160 165 gga acg cag ttc acc caa acc ggt tcc gtc agc tgg gcc ggt ttg gcc 643 Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser Trp Ala Gly Leu Ala 170 175 180 gcc gca gtt ggc gtg ggg tcg atg tct gct ggc gtg aac ttg gcc aac 691 Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly Val Asn Leu Ala Asn 185 190 195 aat att cgc gat att cca acc gat agc aag acc gga aaa att acc ctc 739 Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr Gly Lys Ile Thr Leu 200 205 210 gcg gtc cgc ctg ggc gat gcg ggt gct cgt aag ctg ttc ctc gcg ctg 787 Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys Leu Phe Leu Ala Leu 215 220 225 att tcc acg ccg ttc atc atg tcc atc tgc ctg gcg ttt gtc gcc tgg 835 Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu Ala Phe Val Ala Trp 230 235 240 245 cca gcg ctg atc gcg atc atc gtt ttc ccg ctg gca ctg aaa gcc gca 883 Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu Ala Leu Lys Ala Ala 250 255 260 ggg ccg atc cgc aac aac gcc acc ggc aag gat ctc atc ccg tca tcg 931 Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp Leu Ile Pro Ser Ser 265 270 275 gct caa cag ggc gcg cca tgg cgt tgt ggg ccg tgc tca cgg gcc tgg 979 Ala Gln Gln Gly Ala Pro Trp Arg Cys Gly Pro Cys Ser Arg Ala Trp 280 285 290 cat tagcgtttag ctaaaacgct ttt 1005 His <210> 480 <211> 294 <212> PRT <213> Corynebacterium glutamicum <400> 480 Met Ser His Thr Glu Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp 1 5 10 15 Ile Gln Gly Ala Arg Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val 20 25 30 Ile Ala Gly Ser Gly Val Ala Ala Phe His Asp Gly Phe Val Trp Trp 35 40 45 Lys Ala Leu Leu Ala Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val 50 55 60 Asn Tyr Ala Asn Asp Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp 65 70 75 80 Arg Thr Gly Pro Leu Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys 85 90 95 Lys Val Lys Ala Ala Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala 100 105 110 Gly Thr Ala Leu Ser Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly 115 120 125 Ile Leu Cys Val Leu Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro 130 135 140 Tyr Gly Tyr Arg Gly Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly 145 150 155 160 Leu Val Ala Val Met Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser 165 170 175 Trp Ala Gly Leu Ala Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly 180 185 190 Val Asn Leu Ala Asn Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr 195 200 205 Gly Lys Ile Thr Leu Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys 210 215 220 Leu Phe Leu Ala Leu Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu 225 230 235 240 Ala Phe Val Ala Trp Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu 245 250 255 Ala Leu Lys Ala Ala Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp 260 265 270 Leu Ile Pro Ser Ser Ala Gln Gln Gly Ala Pro Trp Arg Cys Gly Pro 275 280 285 Cys Ser Arg Ala Trp His 290 <210> 481 <211> 987 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(964) <223> RXS00446 <400> 481 tgctacgaag ttatctagta atgaagttag tttttcccct ctcccggcag cagttgatgc 60 ggtgacggag gctacttggg gggctaatcg gtacccggat atg ggt gcg gtt gag 115 Met Gly Ala Val Glu 1 5 ctc cgt gag gct ctt gca gag cat tta gag gtt gag ttt gac cag gtc 163 Leu Arg Glu Ala Leu Ala Glu His Leu Glu Val Glu Phe Asp Gln Val 10 15 20 acg gta ggt tgc ggc tcg tct gcg ctg tgt caa cag ctg gtt cag gca 211 Thr Val Gly Cys Gly Ser Ser Ala Leu Cys Gln Gln Leu Val Gln Ala 25 30 35 acg tgc gct cag ggc gat gag gtc att ttt cca tgg cgc agc ttt gag 259 Thr Cys Ala Gln Gly Asp Glu Val Ile Phe Pro Trp Arg Ser Phe Glu 40 45 50 gct tat cca att ttc gcg cag gtc gcg ggc gcc act cct gtt gcc att 307 Ala Tyr Pro Ile Phe Ala Gln Val Ala Gly Ala Thr Pro Val Ala Ile 55 60 65 ccg ctg act gct gat cag aat cat gat ctt gat gcg atg gca gcc gcg 355 Pro Leu Thr Ala Asp Gln Asn His Asp Leu Asp Ala Met Ala Ala Ala 70 75 80 85 atc act gat aag acc cgc ctc att ttc atc tgc aac ccc aac aat cct 403 Ile Thr Asp Lys Thr Arg Leu Ile Phe Ile Cys Asn Pro Asn Asn Pro 90 95 100 tcg ggc acc acc atc acc cag gcg cag ttt gat aat ttc atg gaa aag 451 Ser Gly Thr Thr Ile Thr Gln Ala Gln Phe Asp Asn Phe Met Glu Lys 105 110 115 gtt cca aac gat gtc gtt gtt ggg ctg gat gag gct tat ttt gag ttc 499 Val Pro Asn Asp Val Val Val Gly Leu Asp Glu Ala Tyr Phe Glu Phe 120 125 130 aac cgc gcg gac gac acc cca gtt gcc act gag gaa atc cac cgc cac 547 Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu Glu Ile His Arg His 135 140 145 gac aac gtg att ggt ttg cgc acg ttc tcc aag gcg tat ggc ctg gcg 595 Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys Ala Tyr Gly Leu Ala 150 155 160 165 ggc ttg cgt gtt ggt tac gcc ttc gga aac gca gag atc atc gca gcg 643 Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala Glu Ile Ile Ala Ala 170 175 180 atg aat aag gtg gct att cct ttc gcg gtg aat tca gca gct cag gcg 691 Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn Ser Ala Ala Gln Ala 185 190 195 gca gcg ctt gcg agt ttg aat tct gcc gat gag ttg atg gaa cgg gtg 739 Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu Leu Met Glu Arg Val 200 205 210 gag gaa acc gtc gaa aag cgt gat gct gtg gtg tca gcg ctt ggt gct 787 Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val Ser Ala Leu Gly Ala 215 220 225 gcg ccg acg cag gcc aat ttc gtc tgg ctg ccg ggc gag ggc gcc gct 835 Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro Gly Glu Gly Ala Ala 230 235 240 245 gag ttg gcg gct aaa ttg gcc gag cac ggc atc gtg att cgc gcg ttc 883 Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile Val Ile Arg Ala Phe 250 255 260 ccc gag ggt gcg cgc att tcg gtg acc aac gcc gag gaa act gac aag 931 Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala Glu Glu Thr Asp Lys 265 270 275 ctg ctg cgc gcg tgg gag gcc atc aat gct ggg tagtctttgg cgttttgcgg 984 Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 280 285 tgc 987 <210> 482 <211> 288 <212> PRT <213> Corynebacterium glutamicum <400> 482 Met Gly Ala Val Glu Leu Arg Glu Ala Leu Ala Glu His Leu Glu Val 1 5 10 15 Glu Phe Asp Gln Val Thr Val Gly Cys Gly Ser Ser Ala Leu Cys Gln 20 25 30 Gln Leu Val Gln Ala Thr Cys Ala Gln Gly Asp Glu Val Ile Phe Pro 35 40 45 Trp Arg Ser Phe Glu Ala Tyr Pro Ile Phe Ala Gln Val Ala Gly Ala 50 55 60 Thr Pro Val Ala Ile Pro Leu Thr Ala Asp Gln Asn His Asp Leu Asp 65 70 75 80 Ala Met Ala Ala Ala Ile Thr Asp Lys Thr Arg Leu Ile Phe Ile Cys 85 90 95 Asn Pro Asn Asn Pro Ser Gly Thr Thr Ile Thr Gln Ala Gln Phe Asp 100 105 110 Asn Phe Met Glu Lys Val Pro Asn Asp Val Val Val Gly Leu Asp Glu 115 120 125 Ala Tyr Phe Glu Phe Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu 130 135 140 Glu Ile His Arg His Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys 145 150 155 160 Ala Tyr Gly Leu Ala Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala 165 170 175 Glu Ile Ile Ala Ala Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn 180 185 190 Ser Ala Ala Gln Ala Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu 195 200 205 Leu Met Glu Arg Val Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val 210 215 220 Ser Ala Leu Gly Ala Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro 225 230 235 240 Gly Glu Gly Ala Ala Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile 245 250 255 Val Ile Arg Ala Phe Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala 260 265 270 Glu Glu Thr Asp Lys Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 275 280 285 <210> 483 <211> 545 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(522) <223> FRXA00446 <400> 483 atg gaa aag gtt cca aac gat gtc gtt gtt ggg ctg gat gag gct tat 48 Met Glu Lys Val Pro Asn Asp Val Val Val Gly Leu Asp Glu Ala Tyr 1 5 10 15 ttt gag ttc aac cgc gcg gac gac acc cca gtt gcc act gag gaa atc 96 Phe Glu Phe Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu Glu Ile 20 25 30 cac cgc cac gac aac gtg att ggt ttg cgc acg ttc tcc aag gcg tat 144 His Arg His Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys Ala Tyr 35 40 45 ggc ctg gcg ggc ttg cgt gtt ggt tac gcc ttc gga aac gca gag atc 192 Gly Leu Ala Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala Glu Ile 50 55 60 atc gca gcg atg aat aag gtg gct att cct ttc gcg gtg aat tca gca 240 Ile Ala Ala Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn Ser Ala 65 70 75 80 gct cag gcg gca gcg ctt gcg agt ttg aat tct gcc gat gag ttg atg 288 Ala Gln Ala Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu Leu Met 85 90 95 gaa cgg gtg gag gaa acc gtc gaa aag cgt gat gct gtg gtg tca gcg 336 Glu Arg Val Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val Ser Ala 100 105 110 ctt ggt gct gcg ccg acg cag gcc aat ttc gtc tgg ctg ccg ggc gag 384 Leu Gly Ala Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro Gly Glu 115 120 125 ggc gcc gct gag ttg gcg gct aaa ttg gcc gag cac ggc atc gtg att 432 Gly Ala Ala Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile Val Ile 130 135 140 cgc gcg ttc ccc gag ggt gcg cgc att tcg gtg acc aac gcc gag gaa 480 Arg Ala Phe Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala Glu Glu 145 150 155 160 act gac aag ctg ctg cgc gcg tgg gag gcc atc aat gct ggg 522 Thr Asp Lys Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 165 170 tagtctttgg cgttttgcgg tgc 545 <210> 484 <211> 174 <212> PRT <213> Corynebacterium glutamicum <400> 484 Met Glu Lys Val Pro Asn Asp Val Val Val Gly Leu Asp Glu Ala Tyr 1 5 10 15 Phe Glu Phe Asn Arg Ala Asp Asp Thr Pro Val Ala Thr Glu Glu Ile 20 25 30 His Arg His Asp Asn Val Ile Gly Leu Arg Thr Phe Ser Lys Ala Tyr 35 40 45 Gly Leu Ala Gly Leu Arg Val Gly Tyr Ala Phe Gly Asn Ala Glu Ile 50 55 60 Ile Ala Ala Met Asn Lys Val Ala Ile Pro Phe Ala Val Asn Ser Ala 65 70 75 80 Ala Gln Ala Ala Ala Leu Ala Ser Leu Asn Ser Ala Asp Glu Leu Met 85 90 95 Glu Arg Val Glu Glu Thr Val Glu Lys Arg Asp Ala Val Val Ser Ala 100 105 110 Leu Gly Ala Ala Pro Thr Gln Ala Asn Phe Val Trp Leu Pro Gly Glu 115 120 125 Gly Ala Ala Glu Leu Ala Ala Lys Leu Ala Glu His Gly Ile Val Ile 130 135 140 Arg Ala Phe Pro Glu Gly Ala Arg Ile Ser Val Thr Asn Ala Glu Glu 145 150 155 160 Thr Asp Lys Leu Leu Arg Ala Trp Glu Ala Ile Asn Ala Gly 165 170 <210> 485 <211> 1230 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1207) <223> RXS00618 <400> 485 gctgcattag agggtcgtat ctcgatctaa aagcagtacg cagataggct tgtctcttat 60 gaagccaagc actagaagca atgttcagcc gtttcgcgtc atg cag atg ttg gac 115 Met Gln Met Leu Asp 1 5 cga gtc cac cgt cgc agg cgc gaa ggc aaa gac acc tta atg ttc tgc 163 Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp Thr Leu Met Phe Cys 10 15 20 gct ggc cag ccg tca act ggt gcg cca gaa gca gtc atc gaa gaa gca 211 Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala Val Ile Glu Glu Ala 25 30 35 gag atc gct ctt cgc tcg ggt cct ttg gga tac acc gag gtg att ggt 259 Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr Thr Glu Val Ile Gly 40 45 50 gat cgt gag ttc cgt gaa cgc atc gcc gat tgg cac tct gct act tat 307 Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp His Ser Ala Thr Tyr 55 60 65 gac gta gac acc aac cct gac aat gtt att gtc acc acc ggt tct tca 355 Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val Thr Thr Gly Ser Ser 70 75 80 85 ggt gga ttc gtg gca tcg ttt atc gcc acc ttg gat cac ggg gat tat 403 Gly Gly Phe Val Ala Ser Phe Ile Ala Thr Leu Asp His Gly Asp Tyr 90 95 100 gtg gca atg cct acc ccg ggg tac ccg gca tat cgc aat att ctg gaa 451 Val Ala Met Pro Thr Pro Gly Tyr Pro Ala Tyr Arg Asn Ile Leu Glu 105 110 115 tct ttg ggg gcg aag gtt ctg aac ctg cgc tgt act gca gag act cgt 499 Ser Leu Gly Ala Lys Val Leu Asn Leu Arg Cys Thr Ala Glu Thr Arg 120 125 130 ttc cag cca acc gct caa atg ttg gag gaa ctg cca cac aag ccg aag 547 Phe Gln Pro Thr Ala Gln Met Leu Glu Glu Leu Pro His Lys Pro Lys 135 140 145 gct gtt att gtc acc agc cca gga aac cca acg ggc acc atc att gat 595 Ala Val Ile Val Thr Ser Pro Gly Asn Pro Thr Gly Thr Ile Ile Asp 150 155 160 165 ccg gaa gag cta gag cgc atc gcc aag tgg tgc gat gac aat gat gct 643 Pro Glu Glu Leu Glu Arg Ile Ala Lys Trp Cys Asp Asp Asn Asp Ala 170 175 180 gtt ctt atc tct gat gag gac tac cac ggc atg agc ttt ggt cgt ccg 691 Val Leu Ile Ser Asp Glu Asp Tyr His Gly Met Ser Phe Gly Arg Pro 185 190 195 ctg gca act gcg cat cag ttt tcc aag aac gcc atc gtg gtg ggt acc 739 Leu Ala Thr Ala His Gln Phe Ser Lys Asn Ala Ile Val Val Gly Thr 200 205 210 ttg tcc aag tac ttc tcc atg acg ggt tgg cgc gtg ggt tgg atc atc 787 Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp Arg Val Gly Trp Ile Ile 215 220 225 gtt cca gat gag ctg gtc aca ccg att gaa aac ctg cag gct tct ctt 835 Val Pro Asp Glu Leu Val Thr Pro Ile Glu Asn Leu Gln Ala Ser Leu 230 235 240 245 tcc ttg tgt gct cct gcc atc ggg cag gct gcg gga cgc gca gcc ttc 883 Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala Ala Gly Arg Ala Ala Phe 250 255 260 act ttg gag gct ggg gcc gaa ctt gat gcc cac gtt gaa gcg tat cgc 931 Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala His Val Glu Ala Tyr Arg 265 270 275 gag gcc cgg gag gtg ttc gtc gat aag ctc cct gaa atc ggg ctt ggc 979 Glu Ala Arg Glu Val Phe Val Asp Lys Leu Pro Glu Ile Gly Leu Gly 280 285 290 act ttc gcc gac ccg gat ggc ggc ctg tat ttg tgg gtc gat gtt tct 1027 Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr Leu Trp Val Asp Val Ser 295 300 305 gca tac acc gat gat tca gag gaa tgg gca ttg cgt ttg ctc gat gaa 1075 Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala Leu Arg Leu Leu Asp Glu 310 315 320 325 gcg ggc gtg gcc gtc gcg ccg ggt gtt gat ttt gat cct gag gaa ggc 1123 Ala Gly Val Ala Val Ala Pro Gly Val Asp Phe Asp Pro Glu Glu Gly 330 335 340 cac aag tgg att cgt ttg agc ctg tgc gcg tca aag gaa gac acc att 1171 His Lys Trp Ile Arg Leu Ser Leu Cys Ala Ser Lys Glu Asp Thr Ile 345 350 355 gaa ggt gtg cgc aaa atc gga gaa ttc atc aaa aaa tagcagcgac 1217 Glu Gly Val Arg Lys Ile Gly Glu Phe Ile Lys Lys 360 365 taggttagtt tcg 1230 <210> 486 <211> 369 <212> PRT <213> Corynebacterium glutamicum <400> 486 Met Gln Met Leu Asp Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp 1 5 10 15 Thr Leu Met Phe Cys Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala 20 25 30 Val Ile Glu Glu Ala Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr 35 40 45 Thr Glu Val Ile Gly Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp 50 55 60 His Ser Ala Thr Tyr Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val 65 70 75 80 Thr Thr Gly Ser Ser Gly Gly Phe Val Ala Ser Phe Ile Ala Thr Leu 85 90 95 Asp His Gly Asp Tyr Val Ala Met Pro Thr Pro Gly Tyr Pro Ala Tyr 100 105 110 Arg Asn Ile Leu Glu Ser Leu Gly Ala Lys Val Leu Asn Leu Arg Cys 115 120 125 Thr Ala Glu Thr Arg Phe Gln Pro Thr Ala Gln Met Leu Glu Glu Leu 130 135 140 Pro His Lys Pro Lys Ala Val Ile Val Thr Ser Pro Gly Asn Pro Thr 145 150 155 160 Gly Thr Ile Ile Asp Pro Glu Glu Leu Glu Arg Ile Ala Lys Trp Cys 165 170 175 Asp Asp Asn Asp Ala Val Leu Ile Ser Asp Glu Asp Tyr His Gly Met 180 185 190 Ser Phe Gly Arg Pro Leu Ala Thr Ala His Gln Phe Ser Lys Asn Ala 195 200 205 Ile Val Val Gly Thr Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp Arg 210 215 220 Val Gly Trp Ile Ile Val Pro Asp Glu Leu Val Thr Pro Ile Glu Asn 225 230 235 240 Leu Gln Ala Ser Leu Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala Ala 245 250 255 Gly Arg Ala Ala Phe Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala His 260 265 270 Val Glu Ala Tyr Arg Glu Ala Arg Glu Val Phe Val Asp Lys Leu Pro 275 280 285 Glu Ile Gly Leu Gly Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr Leu 290 295 300 Trp Val Asp Val Ser Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala Leu 305 310 315 320 Arg Leu Leu Asp Glu Ala Gly Val Ala Val Ala Pro Gly Val Asp Phe 325 330 335 Asp Pro Glu Glu Gly His Lys Trp Ile Arg Leu Ser Leu Cys Ala Ser 340 345 350 Lys Glu Asp Thr Ile Glu Gly Val Arg Lys Ile Gly Glu Phe Ile Lys 355 360 365 Lys <210> 487 <211> 657 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(634) <223> FRXA00618 <400> 487 cccaacgggc accatcattg atccggaaga gctagagcgc atcgccaagt ggtgcgatga 60 caatgatgct gttcttatct ctgatgagga ctaccacggc atg agc ttt ggt cgt 115 Met Ser Phe Gly Arg 1 5 ccg ctg gca act gcg cat cag ttt tcc aag aac gcc atc gtg gtg ggt 163 Pro Leu Ala Thr Ala His Gln Phe Ser Lys Asn Ala Ile Val Val Gly 10 15 20 acc ttg tcc aag tac ttc tcc atg acg ggt tgg cgc gtg ggt tgg atc 211 Thr Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp Arg Val Gly Trp Ile 25 30 35 atc gtt cca gat gag ctg gtc aca ccg att gaa aac ctg cag gct tct 259 Ile Val Pro Asp Glu Leu Val Thr Pro Ile Glu Asn Leu Gln Ala Ser 40 45 50 ctt tcc ttg tgt gct cct gcc atc ggg cag gct gcg gga cgc gca gcc 307 Leu Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala Ala Gly Arg Ala Ala 55 60 65 ttc act ttg gag gct ggg gcc gaa ctt gat gcc cac gtt gaa gcg tat 355 Phe Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala His Val Glu Ala Tyr 70 75 80 85 cgc gag gcc cgg gag gtg ttc gtc gat aag ctc cct gaa atc ggg ctt 403 Arg Glu Ala Arg Glu Val Phe Val Asp Lys Leu Pro Glu Ile Gly Leu 90 95 100 ggc act ttc gcc gac ccg gat ggc ggc ctg tat ttg tgg gtc gat gtt 451 Gly Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr Leu Trp Val Asp Val 105 110 115 tct gca tac acc gat gat tca gag gaa tgg gca ttg cgt ttg ctc gat 499 Ser Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala Leu Arg Leu Leu Asp 120 125 130 gaa gcg ggc gtg gcc gtc gcg ccg ggt gtt gat ttt gat cct gag gaa 547 Glu Ala Gly Val Ala Val Ala Pro Gly Val Asp Phe Asp Pro Glu Glu 135 140 145 ggc cac aag tgg att cgt ttg agc ctg tgc gcg tca aag gaa gac acc 595 Gly His Lys Trp Ile Arg Leu Ser Leu Cys Ala Ser Lys Glu Asp Thr 150 155 160 165 att gaa ggt gtg cgc aaa atc gga gaa ttc atc aaa aaa tagcagcgac 644 Ile Glu Gly Val Arg Lys Ile Gly Glu Phe Ile Lys Lys 170 175 taggttagtt tcg 657 <210> 488 <211> 178 <212> PRT <213> Corynebacterium glutamicum <400> 488 Met Ser Phe Gly Arg Pro Leu Ala Thr Ala His Gln Phe Ser Lys Asn 1 5 10 15 Ala Ile Val Val Gly Thr Leu Ser Lys Tyr Phe Ser Met Thr Gly Trp 20 25 30 Arg Val Gly Trp Ile Ile Val Pro Asp Glu Leu Val Thr Pro Ile Glu 35 40 45 Asn Leu Gln Ala Ser Leu Ser Leu Cys Ala Pro Ala Ile Gly Gln Ala 50 55 60 Ala Gly Arg Ala Ala Phe Thr Leu Glu Ala Gly Ala Glu Leu Asp Ala 65 70 75 80 His Val Glu Ala Tyr Arg Glu Ala Arg Glu Val Phe Val Asp Lys Leu 85 90 95 Pro Glu Ile Gly Leu Gly Thr Phe Ala Asp Pro Asp Gly Gly Leu Tyr 100 105 110 Leu Trp Val Asp Val Ser Ala Tyr Thr Asp Asp Ser Glu Glu Trp Ala 115 120 125 Leu Arg Leu Leu Asp Glu Ala Gly Val Ala Val Ala Pro Gly Val Asp 130 135 140 Phe Asp Pro Glu Glu Gly His Lys Trp Ile Arg Leu Ser Leu Cys Ala 145 150 155 160 Ser Lys Glu Asp Thr Ile Glu Gly Val Arg Lys Ile Gly Glu Phe Ile 165 170 175 Lys Lys <210> 489 <211> 385 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(385) <223> FRXA00627 <400> 489 gctgcattag agggtcgtat ctcgatctaa aagcagtacg cagataggct tgtctcttat 60 gaagccaagc actagaagca atgttcagcc gtttcgcgtc atg cag atg ttg gac 115 Met Gln Met Leu Asp 1 5 cga gtc cac cgt cgc agg cgc gaa ggc aaa gac acc tta atg ttc tgc 163 Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp Thr Leu Met Phe Cys 10 15 20 gct ggc cag ccg tca act ggt gcg cca gaa gca gtc atc gaa gaa gca 211 Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala Val Ile Glu Glu Ala 25 30 35 gag atc gct ctt cgc tcg ggt cct ttg gga tac acc gag gtg att ggt 259 Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr Thr Glu Val Ile Gly 40 45 50 gat cgt gag ttc cgt gaa cgc atc gcc gat tgg cac tct gct act tat 307 Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp His Ser Ala Thr Tyr 55 60 65 gac gta gac acc aac cct gac aat gtt att gtc acc acc ggt tct tca 355 Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val Thr Thr Gly Ser Ser 70 75 80 85 ggt gga ttc gtg gca tcg ttt atc gcc acc 385 Gly Gly Phe Val Ala Ser Phe Ile Ala Thr 90 95 <210> 490 <211> 95 <212> PRT <213> Corynebacterium glutamicum <400> 490 Met Gln Met Leu Asp Arg Val His Arg Arg Arg Arg Glu Gly Lys Asp 1 5 10 15 Thr Leu Met Phe Cys Ala Gly Gln Pro Ser Thr Gly Ala Pro Glu Ala 20 25 30 Val Ile Glu Glu Ala Glu Ile Ala Leu Arg Ser Gly Pro Leu Gly Tyr 35 40 45 Thr Glu Val Ile Gly Asp Arg Glu Phe Arg Glu Arg Ile Ala Asp Trp 50 55 60 His Ser Ala Thr Tyr Asp Val Asp Thr Asn Pro Asp Asn Val Ile Val 65 70 75 80 Thr Thr Gly Ser Ser Gly Gly Phe Val Ala Ser Phe Ile Ala Thr 85 90 95 <210> 491 <211> 1221 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1198) <223> RXS01105 <400> 491 ttgtcatcaa ctttgccaac gccgaagatc ttccagcgca cggcgaagca atccgtgcac 60 gctttgaaaa cctccccacc accgacgagg cctaagaaaa atg acc aaa att act 115 Met Thr Lys Ile Thr 1 5 ttg agc gat ttg cca ttg cgt gaa gaa ctg cgc ggt gag cac gct tac 163 Leu Ser Asp Leu Pro Leu Arg Glu Glu Leu Arg Gly Glu His Ala Tyr 10 15 20 ggc gca ccc cag ctc aac gtt gat att cgc ctc aac acc aac gaa aac 211 Gly Ala Pro Gln Leu Asn Val Asp Ile Arg Leu Asn Thr Asn Glu Asn 25 30 35 cct tac cca ccg tca gag gca ttg gtc gct gac ttg gtt gcc acc gtg 259 Pro Tyr Pro Pro Ser Glu Ala Leu Val Ala Asp Leu Val Ala Thr Val 40 45 50 gat aag atc gcc acc gag ctg aac cgc tac cca gag cgc gat gct gtg 307 Asp Lys Ile Ala Thr Glu Leu Asn Arg Tyr Pro Glu Arg Asp Ala Val 55 60 65 gaa ctg cgt gat gag ttg gct gcg tac atc acc aag caa acc ggc gtg 355 Glu Leu Arg Asp Glu Leu Ala Ala Tyr Ile Thr Lys Gln Thr Gly Val 70 75 80 85 gct gtc acc agg gat aac ctg tgg gct gcc aat ggt tcc aat gaa att 403 Ala Val Thr Arg Asp Asn Leu Trp Ala Ala Asn Gly Ser Asn Glu Ile 90 95 100 ctg cag cag ctg ctg cag gct ttt ggt gga cct gga cgc acc gcg ttg 451 Leu Gln Gln Leu Leu Gln Ala Phe Gly Gly Pro Gly Arg Thr Ala Leu 105 110 115 gga ttc caa ccc agc tat tcc atg cac cca att ttg gct aaa ggc acc 499 Gly Phe Gln Pro Ser Tyr Ser Met His Pro Ile Leu Ala Lys Gly Thr 120 125 130 cac act gaa ttc att gcg gtg tcc cga ggt gct gat ttc cgc atc gat 547 His Thr Glu Phe Ile Ala Val Ser Arg Gly Ala Asp Phe Arg Ile Asp 135 140 145 atg gat gtg gcg ctg gaa gaa att cgt gca aag cag cct gac att gtt 595 Met Asp Val Ala Leu Glu Glu Ile Arg Ala Lys Gln Pro Asp Ile Val 150 155 160 165 ttt gtc acc acc ccg aac aac ccg acc ggt gat gtg acc tcg ctg gac 643 Phe Val Thr Thr Pro Asn Asn Pro Thr Gly Asp Val Thr Ser Leu Asp 170 175 180 gat gtt gag cgc atc atc aac gtt gcc cca ggc atc gtg atc gtg gat 691 Asp Val Glu Arg Ile Ile Asn Val Ala Pro Gly Ile Val Ile Val Asp 185 190 195 gaa gct tat gcg gaa ttc tcc cca tca cct tca gca acc act ctt ctg 739 Glu Ala Tyr Ala Glu Phe Ser Pro Ser Pro Ser Ala Thr Thr Leu Leu 200 205 210 gag aag tac cca acc aag ctg gtg gtg tcc cgc acc atg agt aag gct 787 Glu Lys Tyr Pro Thr Lys Leu Val Val Ser Arg Thr Met Ser Lys Ala 215 220 225 ttt gat ttc gca ggt gga cgc ctc ggc tac ttc gtg gcc aac cca gcg 835 Phe Asp Phe Ala Gly Gly Arg Leu Gly Tyr Phe Val Ala Asn Pro Ala 230 235 240 245 ttt atc gac gcc gtg atg cta gtc cgc ctt ccg tat cat ctt tca gcg 883 Phe Ile Asp Ala Val Met Leu Val Arg Leu Pro Tyr His Leu Ser Ala 250 255 260 ctg agc caa gca gcc gca atc gta gcg ctg cgt cac tcc gct gac acg 931 Leu Ser Gln Ala Ala Ala Ile Val Ala Leu Arg His Ser Ala Asp Thr 265 270 275 ctg gga acc gtc gaa aag ctc tct gta gag cgt gtt cgc gtg gca gca 979 Leu Gly Thr Val Glu Lys Leu Ser Val Glu Arg Val Arg Val Ala Ala 280 285 290 cgc ttg gag gaa ctg ggc tac gct gtg gtt cca agt gag tcc aac ttt 1027 Arg Leu Glu Glu Leu Gly Tyr Ala Val Val Pro Ser Glu Ser Asn Phe 295 300 305 gtg ttc ttt gga gat ttc tcc gat cag cac gcg gca tgg cag gca ttt 1075 Val Phe Phe Gly Asp Phe Ser Asp Gln His Ala Ala Trp Gln Ala Phe 310 315 320 325 ttg gat agg gga gtg ctc atc cgc gat gtg gga atc gct ggg cac ttg 1123 Leu Asp Arg Gly Val Leu Ile Arg Asp Val Gly Ile Ala Gly His Leu 330 335 340 cgc act acc att ggt gtg cct gag gaa aat gat gcg ttt ttg gac gca 1171 Arg Thr Thr Ile Gly Val Pro Glu Glu Asn Asp Ala Phe Leu Asp Ala 345 350 355 gct gca gag atc atc aag ctg aac ctg taagagagaa gaatttttca 1218 Ala Ala Glu Ile Ile Lys Leu Asn Leu 360 365 tga 1221 <210> 492 <211> 366 <212> PRT <213> Corynebacterium glutamicum <400> 492 Met Thr Lys Ile Thr Leu Ser Asp Leu Pro Leu Arg Glu Glu Leu Arg 1 5 10 15 Gly Glu His Ala Tyr Gly Ala Pro Gln Leu Asn Val Asp Ile Arg Leu 20 25 30 Asn Thr Asn Glu Asn Pro Tyr Pro Pro Ser Glu Ala Leu Val Ala Asp 35 40 45 Leu Val Ala Thr Val Asp Lys Ile Ala Thr Glu Leu Asn Arg Tyr Pro 50 55 60 Glu Arg Asp Ala Val Glu Leu Arg Asp Glu Leu Ala Ala Tyr Ile Thr 65 70 75 80 Lys Gln Thr Gly Val Ala Val Thr Arg Asp Asn Leu Trp Ala Ala Asn 85 90 95 Gly Ser Asn Glu Ile Leu Gln Gln Leu Leu Gln Ala Phe Gly Gly Pro 100 105 110 Gly Arg Thr Ala Leu Gly Phe Gln Pro Ser Tyr Ser Met His Pro Ile 115 120 125 Leu Ala Lys Gly Thr His Thr Glu Phe Ile Ala Val Ser Arg Gly Ala 130 135 140 Asp Phe Arg Ile Asp Met Asp Val Ala Leu Glu Glu Ile Arg Ala Lys 145 150 155 160 Gln Pro Asp Ile Val Phe Val Thr Thr Pro Asn Asn Pro Thr Gly Asp 165 170 175 Val Thr Ser Leu Asp Asp Val Glu Arg Ile Ile Asn Val Ala Pro Gly 180 185 190 Ile Val Ile Val Asp Glu Ala Tyr Ala Glu Phe Ser Pro Ser Pro Ser 195 200 205 Ala Thr Thr Leu Leu Glu Lys Tyr Pro Thr Lys Leu Val Val Ser Arg 210 215 220 Thr Met Ser Lys Ala Phe Asp Phe Ala Gly Gly Arg Leu Gly Tyr Phe 225 230 235 240 Val Ala Asn Pro Ala Phe Ile Asp Ala Val Met Leu Val Arg Leu Pro 245 250 255 Tyr His Leu Ser Ala Leu Ser Gln Ala Ala Ala Ile Val Ala Leu Arg 260 265 270 His Ser Ala Asp Thr Leu Gly Thr Val Glu Lys Leu Ser Val Glu Arg 275 280 285 Val Arg Val Ala Ala Arg Leu Glu Glu Leu Gly Tyr Ala Val Val Pro 290 295 300 Ser Glu Ser Asn Phe Val Phe Phe Gly Asp Phe Ser Asp Gln His Ala 305 310 315 320 Ala Trp Gln Ala Phe Leu Asp Arg Gly Val Leu Ile Arg Asp Val Gly 325 330 335 Ile Ala Gly His Leu Arg Thr Thr Ile Gly Val Pro Glu Glu Asn Asp 340 345 350 Ala Phe Leu Asp Ala Ala Ala Glu Ile Ile Lys Leu Asn Leu 355 360 365 <210> 493 <211> 1752 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1729) <223> RXS02315 <400> 493 cgtttggaaa cgcttgctgc cagcaaagat aggcgtgatt ggtggtttga gcgcgtgcgt 60 gaatcgtatc cgtacctgga gacgatctag actgttgtgc atg tcc agc acg cca 115 Met Ser Ser Thr Pro 1 5 gct caa gat ctt gcc cgc gcc gtt att gat tcc ctc gca cca cac gtc 163 Ala Gln Asp Leu Ala Arg Ala Val Ile Asp Ser Leu Ala Pro His Val 10 15 20 act gac gtg gtg tta tgc cca gga tcc agg aac tca ccg ttg tcg ctt 211 Thr Asp Val Val Leu Cys Pro Gly Ser Arg Asn Ser Pro Leu Ser Leu 25 30 35 gag ttg ctg gcg cgg cag gat ctg cgt gtc cat gtg cgt atc gac gag 259 Glu Leu Leu Ala Arg Gln Asp Leu Arg Val His Val Arg Ile Asp Glu 40 45 50 cgc agc gcc tca ttt ttg gcg ctg tcc cta gcg cgt acc cag gcc cgg 307 Arg Ser Ala Ser Phe Leu Ala Leu Ser Leu Ala Arg Thr Gln Ala Arg 55 60 65 ccg gtg gct gtg gtg atg acc tcc ggc acg gct gta gct aac tgc ctg 355 Pro Val Ala Val Val Met Thr Ser Gly Thr Ala Val Ala Asn Cys Leu 70 75 80 85 cct gct gtt gct gaa gct gcg cat gcc cat atc ccg ttg att gtg ctc 403 Pro Ala Val Ala Glu Ala Ala His Ala His Ile Pro Leu Ile Val Leu 90 95 100 tct gct gac cgt cct gca cat ttg gtg gga acg ggg gcg agc caa acg 451 Ser Ala Asp Arg Pro Ala His Leu Val Gly Thr Gly Ala Ser Gln Thr 105 110 115 att aac cag acc ggt att ttt ggt gat ctt gca ccg acg gtc ggt atc 499 Ile Asn Gln Thr Gly Ile Phe Gly Asp Leu Ala Pro Thr Val Gly Ile 120 125 130 act gag ctg gat cag gta gcg cag att gct gaa agc ctt gct cag ggg 547 Thr Glu Leu Asp Gln Val Ala Gln Ile Ala Glu Ser Leu Ala Gln Gly 135 140 145 gct tcc cag att ccg cgt cat ttc aat ctt gca ctt gat gtt cct ttg 595 Ala Ser Gln Ile Pro Arg His Phe Asn Leu Ala Leu Asp Val Pro Leu 150 155 160 165 gtt gct cct gaa ctg cca gag ctt cat ggt gag gca gtt gga gca tca 643 Val Ala Pro Glu Leu Pro Glu Leu His Gly Glu Ala Val Gly Ala Ser 170 175 180 tgg acg cat cgc tgg atc aac cac ggt gag gtg acc gtg gac ctg ggg 691 Trp Thr His Arg Trp Ile Asn His Gly Glu Val Thr Val Asp Leu Gly 185 190 195 gag cac acc ctc gtg att gcc ggt gat gaa gca tgg gaa gtg gaa ggg 739 Glu His Thr Leu Val Ile Ala Gly Asp Glu Ala Trp Glu Val Glu Gly 200 205 210 ctg gaa gat gtg ccc acc atc gct gaa cct act gca cca aag cct tat 787 Leu Glu Asp Val Pro Thr Ile Ala Glu Pro Thr Ala Pro Lys Pro Tyr 215 220 225 aat ccg gtg cac cca ctg gct gct gaa atc ttg ctg aag gag cag gtc 835 Asn Pro Val His Pro Leu Ala Ala Glu Ile Leu Leu Lys Glu Gln Val 230 235 240 245 tcc gcg gaa ggc tat gtg gta aac acc agg cct gat cat gtg atc gtg 883 Ser Ala Glu Gly Tyr Val Val Asn Thr Arg Pro Asp His Val Ile Val 250 255 260 gtg gga cac ccc acg ctg cac cgc gga gtg ttg aag ttg atg tca gat 931 Val Gly His Pro Thr Leu His Arg Gly Val Leu Lys Leu Met Ser Asp 265 270 275 cct ggc att aaa tta act gtg ctt tca cgc acc gat atc atc act gat 979 Pro Gly Ile Lys Leu Thr Val Leu Ser Arg Thr Asp Ile Ile Thr Asp 280 285 290 ccc ggc cgc cat gcc gat cag gtg ggc agc aca gtg aaa gtc acc ggc 1027 Pro Gly Arg His Ala Asp Gln Val Gly Ser Thr Val Lys Val Thr Gly 295 300 305 acc cag gaa aag cag tgg cta aag atc tgt tcg gca gca tca gaa ctt 1075 Thr Gln Glu Lys Gln Trp Leu Lys Ile Cys Ser Ala Ala Ser Glu Leu 310 315 320 325 gcg gcc gat ggt gtg cgt gac gtc ctg gac aac caa gaa ttc ggt ttc 1123 Ala Ala Asp Gly Val Arg Asp Val Leu Asp Asn Gln Glu Phe Gly Phe 330 335 340 acc ggc ctc cat gtt gcc gca gcc gtg gcg gat acc tta ggc acc ggc 1171 Thr Gly Leu His Val Ala Ala Ala Val Ala Asp Thr Leu Gly Thr Gly 345 350 355 gat act ctc ttt gct gca gca tcc aac tca atc cgt gac ctc tcc ctg 1219 Asp Thr Leu Phe Ala Ala Ala Ser Asn Ser Ile Arg Asp Leu Ser Leu 360 365 370 gtg ggt atg cct ttt gat ggc gtg gat acc ttc tcc cca cga ggt gtc 1267 Val Gly Met Pro Phe Asp Gly Val Asp Thr Phe Ser Pro Arg Gly Val 375 380 385 gca ggc att gat ggt tct gtt gct caa gca atc ggc act tca ctt gct 1315 Ala Gly Ile Asp Gly Ser Val Ala Gln Ala Ile Gly Thr Ser Leu Ala 390 395 400 405 gtg cag tcc cgc cac ccc gat gaa atc cgc gcg cca cgc act gtg gcc 1363 Val Gln Ser Arg His Pro Asp Glu Ile Arg Ala Pro Arg Thr Val Ala 410 415 420 ctt ctg ggc gat ctg tcg ttc ctt cac gat att ggc gga ctg ctc atc 1411 Leu Leu Gly Asp Leu Ser Phe Leu His Asp Ile Gly Gly Leu Leu Ile 425 430 435 ggc cct gat gaa cca cgc cca gaa aac ctc acc atc gtg gtc tcc aac 1459 Gly Pro Asp Glu Pro Arg Pro Glu Asn Leu Thr Ile Val Val Ser Asn 440 445 450 gac aac ggt ggc gga atc ttc gaa ctc cta gaa acc ggc gca gat ggt 1507 Asp Asn Gly Gly Gly Ile Phe Glu Leu Leu Glu Thr Gly Ala Asp Gly 455 460 465 ctc cgc ccc aac ttc gag cgt gct ttc ggt acc cca cac gac gcg tcc 1555 Leu Arg Pro Asn Phe Glu Arg Ala Phe Gly Thr Pro His Asp Ala Ser 470 475 480 485 atc gcg gat ctc tgc gca ggc tac ggc att gaa cac caa gtg gta gac 1603 Ile Ala Asp Leu Cys Ala Gly Tyr Gly Ile Glu His Gln Val Val Asp 490 495 500 aac ctc caa gac ctc atc atc gcg cta gtt gat acc acc gaa gta tcc 1651 Asn Leu Gln Asp Leu Ile Ile Ala Leu Val Asp Thr Thr Glu Val Ser 505 510 515 gga ttc acc att att gaa gct tcg acc gtc cga gat acc cgc cgt gca 1699 Gly Phe Thr Ile Ile Glu Ala Ser Thr Val Arg Asp Thr Arg Arg Ala 520 525 530 caa cag caa gct ctc atg gac acg gtg cac taaatggagt ggtaccaagt 1749 Gln Gln Gln Ala Leu Met Asp Thr Val His 535 540 gcg 1752 <210> 494 <211> 543 <212> PRT <213> Corynebacterium glutamicum <400> 494 Met Ser Ser Thr Pro Ala Gln Asp Leu Ala Arg Ala Val Ile Asp Ser 1 5 10 15 Leu Ala Pro His Val Thr Asp Val Val Leu Cys Pro Gly Ser Arg Asn 20 25 30 Ser Pro Leu Ser Leu Glu Leu Leu Ala Arg Gln Asp Leu Arg Val His 35 40 45 Val Arg Ile Asp Glu Arg Ser Ala Ser Phe Leu Ala Leu Ser Leu Ala 50 55 60 Arg Thr Gln Ala Arg Pro Val Ala Val Val Met Thr Ser Gly Thr Ala 65 70 75 80 Val Ala Asn Cys Leu Pro Ala Val Ala Glu Ala Ala His Ala His Ile 85 90 95 Pro Leu Ile Val Leu Ser Ala Asp Arg Pro Ala His Leu Val Gly Thr 100 105 110 Gly Ala Ser Gln Thr Ile Asn Gln Thr Gly Ile Phe Gly Asp Leu Ala 115 120 125 Pro Thr Val Gly Ile Thr Glu Leu Asp Gln Val Ala Gln Ile Ala Glu 130 135 140 Ser Leu Ala Gln Gly Ala Ser Gln Ile Pro Arg His Phe Asn Leu Ala 145 150 155 160 Leu Asp Val Pro Leu Val Ala Pro Glu Leu Pro Glu Leu His Gly Glu 165 170 175 Ala Val Gly Ala Ser Trp Thr His Arg Trp Ile Asn His Gly Glu Val 180 185 190 Thr Val Asp Leu Gly Glu His Thr Leu Val Ile Ala Gly Asp Glu Ala 195 200 205 Trp Glu Val Glu Gly Leu Glu Asp Val Pro Thr Ile Ala Glu Pro Thr 210 215 220 Ala Pro Lys Pro Tyr Asn Pro Val His Pro Leu Ala Ala Glu Ile Leu 225 230 235 240 Leu Lys Glu Gln Val Ser Ala Glu Gly Tyr Val Val Asn Thr Arg Pro 245 250 255 Asp His Val Ile Val Val Gly His Pro Thr Leu His Arg Gly Val Leu 260 265 270 Lys Leu Met Ser Asp Pro Gly Ile Lys Leu Thr Val Leu Ser Arg Thr 275 280 285 Asp Ile Ile Thr Asp Pro Gly Arg His Ala Asp Gln Val Gly Ser Thr 290 295 300 Val Lys Val Thr Gly Thr Gln Glu Lys Gln Trp Leu Lys Ile Cys Ser 305 310 315 320 Ala Ala Ser Glu Leu Ala Ala Asp Gly Val Arg Asp Val Leu Asp Asn 325 330 335 Gln Glu Phe Gly Phe Thr Gly Leu His Val Ala Ala Ala Val Ala Asp 340 345 350 Thr Leu Gly Thr Gly Asp Thr Leu Phe Ala Ala Ala Ser Asn Ser Ile 355 360 365 Arg Asp Leu Ser Leu Val Gly Met Pro Phe Asp Gly Val Asp Thr Phe 370 375 380 Ser Pro Arg Gly Val Ala Gly Ile Asp Gly Ser Val Ala Gln Ala Ile 385 390 395 400 Gly Thr Ser Leu Ala Val Gln Ser Arg His Pro Asp Glu Ile Arg Ala 405 410 415 Pro Arg Thr Val Ala Leu Leu Gly Asp Leu Ser Phe Leu His Asp Ile 420 425 430 Gly Gly Leu Leu Ile Gly Pro Asp Glu Pro Arg Pro Glu Asn Leu Thr 435 440 445 Ile Val Val Ser Asn Asp Asn Gly Gly Gly Ile Phe Glu Leu Leu Glu 450 455 460 Thr Gly Ala Asp Gly Leu Arg Pro Asn Phe Glu Arg Ala Phe Gly Thr 465 470 475 480 Pro His Asp Ala Ser Ile Ala Asp Leu Cys Ala Gly Tyr Gly Ile Glu 485 490 495 His Gln Val Val Asp Asn Leu Gln Asp Leu Ile Ile Ala Leu Val Asp 500 505 510 Thr Thr Glu Val Ser Gly Phe Thr Ile Ile Glu Ala Ser Thr Val Arg 515 520 525 Asp Thr Arg Arg Ala Gln Gln Gln Ala Leu Met Asp Thr Val His 530 535 540 <210> 495 <211> 1434 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1411) <223> RXS02550 <400> 495 gatcttaggc agccgtggga ttacaccctt ttagagctag aacagtaaaa attcacccaa 60 tagctttcaa ctacgcacac aaagtggcaa cattgagcgg gtg act aca gac aag 115 Val Thr Thr Asp Lys 1 5 cgc aaa acc tct aag acc acc gac acc gcc aac aag gct gtg ggc gcg 163 Arg Lys Thr Ser Lys Thr Thr Asp Thr Ala Asn Lys Ala Val Gly Ala 10 15 20 gat cag gca gcg cgt ccc act cgg cga aca act cgc cgc atc ttc gat 211 Asp Gln Ala Ala Arg Pro Thr Arg Arg Thr Thr Arg Arg Ile Phe Asp 25 30 35 cag tcg gag aag atg aag gac gtg ctg tac gag atc cgt ggc ccg gtg 259 Gln Ser Glu Lys Met Lys Asp Val Leu Tyr Glu Ile Arg Gly Pro Val 40 45 50 gcc gcg gag gcg gaa cgc atg gag ctt gat ggg cat aac atc tta aag 307 Ala Ala Glu Ala Glu Arg Met Glu Leu Asp Gly His Asn Ile Leu Lys 55 60 65 ctc aac acg gga aat cca gcc gtg ttc gga ttc gat gcc ccc gac gtg 355 Leu Asn Thr Gly Asn Pro Ala Val Phe Gly Phe Asp Ala Pro Asp Val 70 75 80 85 att atg cgt gac atg atc gcc aac ctt cca act tcc caa ggg tat tcc 403 Ile Met Arg Asp Met Ile Ala Asn Leu Pro Thr Ser Gln Gly Tyr Ser 90 95 100 acc tcc aaa ggc att att ccg gcc cgg cga gca gtg gtc acc cgc tac 451 Thr Ser Lys Gly Ile Ile Pro Ala Arg Arg Ala Val Val Thr Arg Tyr 105 110 115 gaa gtt gtg ccc gga ttc ccc cac ttc gat gtt gat gat gtg ttc tta 499 Glu Val Val Pro Gly Phe Pro His Phe Asp Val Asp Asp Val Phe Leu 120 125 130 ggc aac ggt gtc tca gaa cta atc acc atg acc acc caa gca ctc ctc 547 Gly Asn Gly Val Ser Glu Leu Ile Thr Met Thr Thr Gln Ala Leu Leu 135 140 145 aac gac ggc gat gaa gtt ctt atc ccc gca ccg gac tac cca ctg tgg 595 Asn Asp Gly Asp Glu Val Leu Ile Pro Ala Pro Asp Tyr Pro Leu Trp 150 155 160 165 act gcc gca acc tcc ctg gct ggt ggt aag cct gtg cac tac ctc tgt 643 Thr Ala Ala Thr Ser Leu Ala Gly Gly Lys Pro Val His Tyr Leu Cys 170 175 180 gat gag gaa gat gac tgg aac cca tcc atc gaa gac atc aag tcc aaa 691 Asp Glu Glu Asp Asp Trp Asn Pro Ser Ile Glu Asp Ile Lys Ser Lys 185 190 195 atc tca gag aaa acc aaa gct att gtg gtg atc aac ccc aac aac ccc 739 Ile Ser Glu Lys Thr Lys Ala Ile Val Val Ile Asn Pro Asn Asn Pro 200 205 210 acg gga gct gtc tac ccg cgc cgg gtg ttg gaa caa atc gtc gag att 787 Thr Gly Ala Val Tyr Pro Arg Arg Val Leu Glu Gln Ile Val Glu Ile 215 220 225 gca cgc gag cat gac ctg ctg att ttg gcc gat gaa atc tac gac cgc 835 Ala Arg Glu His Asp Leu Leu Ile Leu Ala Asp Glu Ile Tyr Asp Arg 230 235 240 245 att ctc tac gat gat gcc gag cac atc agc ctg gca acc ctt gca cca 883 Ile Leu Tyr Asp Asp Ala Glu His Ile Ser Leu Ala Thr Leu Ala Pro 250 255 260 gat ctc ctt tgc atc aca tac aac ggt cta tcc aag gca tac cgc gtc 931 Asp Leu Leu Cys Ile Thr Tyr Asn Gly Leu Ser Lys Ala Tyr Arg Val 265 270 275 gca gga tac cga gct ggc tgg atg gta ttg act gga cca aag caa tac 979 Ala Gly Tyr Arg Ala Gly Trp Met Val Leu Thr Gly Pro Lys Gln Tyr 280 285 290 gca cgt gga ttt att gag ggc ctc gaa ctc ctc gca ggc act cga ctc 1027 Ala Arg Gly Phe Ile Glu Gly Leu Glu Leu Leu Ala Gly Thr Arg Leu 295 300 305 tgc cca aat gtc cca gct cag cac gct att cag gta gct ctg ggt gga 1075 Cys Pro Asn Val Pro Ala Gln His Ala Ile Gln Val Ala Leu Gly Gly 310 315 320 325 cgc cag tcc atc tac gac ctc act ggc gaa cac ggc cga ctc ctg gaa 1123 Arg Gln Ser Ile Tyr Asp Leu Thr Gly Glu His Gly Arg Leu Leu Glu 330 335 340 cag cgc aac atg gca tgg acg aaa ctc aac gaa atc cca ggt gtc agc 1171 Gln Arg Asn Met Ala Trp Thr Lys Leu Asn Glu Ile Pro Gly Val Ser 345 350 355 tgt gtg aaa cca atg gga gct cta tac gcg ttc ccc aag ctc gac ccc 1219 Cys Val Lys Pro Met Gly Ala Leu Tyr Ala Phe Pro Lys Leu Asp Pro 360 365 370 aac gtg tac gaa atc cac gac gac acc caa ctc atg ctg gat ctt ctc 1267 Asn Val Tyr Glu Ile His Asp Asp Thr Gln Leu Met Leu Asp Leu Leu 375 380 385 cgt gcc gag aaa atc ctc atg gtt cag ggc act ggc ttc aac tgg cca 1315 Arg Ala Glu Lys Ile Leu Met Val Gln Gly Thr Gly Phe Asn Trp Pro 390 395 400 405 cat cac gat cac ttc cga gtg gtc acc ctg cca tgg gca tcc cag ttg 1363 His His Asp His Phe Arg Val Val Thr Leu Pro Trp Ala Ser Gln Leu 410 415 420 gaa aac gca att gag cgc ctg ggt aac ttc ctg tcc act tac aag cag 1411 Glu Asn Ala Ile Glu Arg Leu Gly Asn Phe Leu Ser Thr Tyr Lys Gln 425 430 435 tagtagttgt taggattcac cac 1434 <210> 496 <211> 437 <212> PRT <213> Corynebacterium glutamicum <400> 496 Val Thr Thr Asp Lys Arg Lys Thr Ser Lys Thr Thr Asp Thr Ala Asn 1 5 10 15 Lys Ala Val Gly Ala Asp Gln Ala Ala Arg Pro Thr Arg Arg Thr Thr 20 25 30 Arg Arg Ile Phe Asp Gln Ser Glu Lys Met Lys Asp Val Leu Tyr Glu 35 40 45 Ile Arg Gly Pro Val Ala Ala Glu Ala Glu Arg Met Glu Leu Asp Gly 50 55 60 His Asn Ile Leu Lys Leu Asn Thr Gly Asn Pro Ala Val Phe Gly Phe 65 70 75 80 Asp Ala Pro Asp Val Ile Met Arg Asp Met Ile Ala Asn Leu Pro Thr 85 90 95 Ser Gln Gly Tyr Ser Thr Ser Lys Gly Ile Ile Pro Ala Arg Arg Ala 100 105 110 Val Val Thr Arg Tyr Glu Val Val Pro Gly Phe Pro His Phe Asp Val 115 120 125 Asp Asp Val Phe Leu Gly Asn Gly Val Ser Glu Leu Ile Thr Met Thr 130 135 140 Thr Gln Ala Leu Leu Asn Asp Gly Asp Glu Val Leu Ile Pro Ala Pro 145 150 155 160 Asp Tyr Pro Leu Trp Thr Ala Ala Thr Ser Leu Ala Gly Gly Lys Pro 165 170 175 Val His Tyr Leu Cys Asp Glu Glu Asp Asp Trp Asn Pro Ser Ile Glu 180 185 190 Asp Ile Lys Ser Lys Ile Ser Glu Lys Thr Lys Ala Ile Val Val Ile 195 200 205 Asn Pro Asn Asn Pro Thr Gly Ala Val Tyr Pro Arg Arg Val Leu Glu 210 215 220 Gln Ile Val Glu Ile Ala Arg Glu His Asp Leu Leu Ile Leu Ala Asp 225 230 235 240 Glu Ile Tyr Asp Arg Ile Leu Tyr Asp Asp Ala Glu His Ile Ser Leu 245 250 255 Ala Thr Leu Ala Pro Asp Leu Leu Cys Ile Thr Tyr Asn Gly Leu Ser 260 265 270 Lys Ala Tyr Arg Val Ala Gly Tyr Arg Ala Gly Trp Met Val Leu Thr 275 280 285 Gly Pro Lys Gln Tyr Ala Arg Gly Phe Ile Glu Gly Leu Glu Leu Leu 290 295 300 Ala Gly Thr Arg Leu Cys Pro Asn Val Pro Ala Gln His Ala Ile Gln 305 310 315 320 Val Ala Leu Gly Gly Arg Gln Ser Ile Tyr Asp Leu Thr Gly Glu His 325 330 335 Gly Arg Leu Leu Glu Gln Arg Asn Met Ala Trp Thr Lys Leu Asn Glu 340 345 350 Ile Pro Gly Val Ser Cys Val Lys Pro Met Gly Ala Leu Tyr Ala Phe 355 360 365 Pro Lys Leu Asp Pro Asn Val Tyr Glu Ile His Asp Asp Thr Gln Leu 370 375 380 Met Leu Asp Leu Leu Arg Ala Glu Lys Ile Leu Met Val Gln Gly Thr 385 390 395 400 Gly Phe Asn Trp Pro His His Asp His Phe Arg Val Val Thr Leu Pro 405 410 415 Trp Ala Ser Gln Leu Glu Asn Ala Ile Glu Arg Leu Gly Asn Phe Leu 420 425 430 Ser Thr Tyr Lys Gln 435 <210> 497 <211> 1080 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1057) <223> RXS02319 <400> 497 atgtgggtga gataaccgac cgtgatgtcg ccctagcaaa agtcatcgac gcccacgcca 60 agaccttggc catttcggca gaggcttaag gttaaagatt atg agc aac tac agc 115 Met Ser Asn Tyr Ser 1 5 acc gac aac cct ttt gat ccc acc caa tgg gcc acc gtt cca ggt ttt 163 Thr Asp Asn Pro Phe Asp Pro Thr Gln Trp Ala Thr Val Pro Gly Phe 10 15 20 gaa gaa ttc acc gac atc acc tac cac cgc cac gtg ggc acc acc cgc 211 Glu Glu Phe Thr Asp Ile Thr Tyr His Arg His Val Gly Thr Thr Arg 25 30 35 gcc gat ggc atc gtg cgc atc gcc ttc gac cgc ccc gaa gtt cgc aat 259 Ala Asp Gly Ile Val Arg Ile Ala Phe Asp Arg Pro Glu Val Arg Asn 40 45 50 gct ttc cgc ccc cac acc gtc gac gag ctt tac caa gcc ctc gac cac 307 Ala Phe Arg Pro His Thr Val Asp Glu Leu Tyr Gln Ala Leu Asp His 55 60 65 gcg cgc cgg acc cca gat gtt gga acc atc ctg ctc acc ggc aac ggc 355 Ala Arg Arg Thr Pro Asp Val Gly Thr Ile Leu Leu Thr Gly Asn Gly 70 75 80 85 ccc agc gaa aaa gac ggt ggc tgg gcg ttc tgc tcc ggc ggc gac caa 403 Pro Ser Glu Lys Asp Gly Gly Trp Ala Phe Cys Ser Gly Gly Asp Gln 90 95 100 cgc atc cgc ggg cgc tcc ggc tac caa tac gcc acc gaa cac gcg cgc 451 Arg Ile Arg Gly Arg Ser Gly Tyr Gln Tyr Ala Thr Glu His Ala Arg 105 110 115 gac gat gcc acc gct gat gtc ttc acg gta gat att gcc cgc acc aaa 499 Asp Asp Ala Thr Ala Asp Val Phe Thr Val Asp Ile Ala Arg Thr Lys 120 125 130 gtt gaa ggc gga cgc ctc cac att ttg gaa gtc caa cgc ctc atc cgc 547 Val Glu Gly Gly Arg Leu His Ile Leu Glu Val Gln Arg Leu Ile Arg 135 140 145 acc atg cct aaa gtt gtc atc gca gta gtc aac ggc tgg gca gcc ggc 595 Thr Met Pro Lys Val Val Ile Ala Val Val Asn Gly Trp Ala Ala Gly 150 155 160 165 ggt ggg cac tcc ctc cat gtc gtt tgc gac ctc acc atc gct tcc cgc 643 Gly Gly His Ser Leu His Val Val Cys Asp Leu Thr Ile Ala Ser Arg 170 175 180 caa gaa gca cgc ttc aag caa acc gac gct gac gtg gga tcc ttc gac 691 Gln Glu Ala Arg Phe Lys Gln Thr Asp Ala Asp Val Gly Ser Phe Asp 185 190 195 gct ggc tac ggc tcc gcc tac cta gcg aaa atg gtc gga cag aaa aac 739 Ala Gly Tyr Gly Ser Ala Tyr Leu Ala Lys Met Val Gly Gln Lys Asn 200 205 210 gcc cgc gaa atc ttc ttc ctc gga cgc acc tac gac gcc gaa cgc atg 787 Ala Arg Glu Ile Phe Phe Leu Gly Arg Thr Tyr Asp Ala Glu Arg Met 215 220 225 caa caa atg ggc gca gtc aac atc gtg gcc gac cac ggc gac cta gaa 835 Gln Gln Met Gly Ala Val Asn Ile Val Ala Asp His Gly Asp Leu Glu 230 235 240 245 aaa gaa gcc atc caa gca gcc cgc gaa atc aac acc aaa tcc ccc acc 883 Lys Glu Ala Ile Gln Ala Ala Arg Glu Ile Asn Thr Lys Ser Pro Thr 250 255 260 ggg caa cgc atg ctg aaa ttc gcc ttc aat ctc acc gac gat ggc ctc 931 Gly Gln Arg Met Leu Lys Phe Ala Phe Asn Leu Thr Asp Asp Gly Leu 265 270 275 atg gga caa caa gtc ttc gcc ggc gaa gcc acc cgc ctg gcc tac atg 979 Met Gly Gln Gln Val Phe Ala Gly Glu Ala Thr Arg Leu Ala Tyr Met 280 285 290 acg gat gaa gcc gta gag ggt aag gaa gca ttc cta gaa aag cgc gaa 1027 Thr Asp Glu Ala Val Glu Gly Lys Glu Ala Phe Leu Glu Lys Arg Glu 295 300 305 ccc aac tgg aat gaa ttc cct tac tac tac tagtgagttc atggggtcct 1077 Pro Asn Trp Asn Glu Phe Pro Tyr Tyr Tyr 310 315 aaa 1080 <210> 498 <211> 319 <212> PRT <213> Corynebacterium glutamicum <400> 498 Met Ser Asn Tyr Ser Thr Asp Asn Pro Phe Asp Pro Thr Gln Trp Ala 1 5 10 15 Thr Val Pro Gly Phe Glu Glu Phe Thr Asp Ile Thr Tyr His Arg His 20 25 30 Val Gly Thr Thr Arg Ala Asp Gly Ile Val Arg Ile Ala Phe Asp Arg 35 40 45 Pro Glu Val Arg Asn Ala Phe Arg Pro His Thr Val Asp Glu Leu Tyr 50 55 60 Gln Ala Leu Asp His Ala Arg Arg Thr Pro Asp Val Gly Thr Ile Leu 65 70 75 80 Leu Thr Gly Asn Gly Pro Ser Glu Lys Asp Gly Gly Trp Ala Phe Cys 85 90 95 Ser Gly Gly Asp Gln Arg Ile Arg Gly Arg Ser Gly Tyr Gln Tyr Ala 100 105 110 Thr Glu His Ala Arg Asp Asp Ala Thr Ala Asp Val Phe Thr Val Asp 115 120 125 Ile Ala Arg Thr Lys Val Glu Gly Gly Arg Leu His Ile Leu Glu Val 130 135 140 Gln Arg Leu Ile Arg Thr Met Pro Lys Val Val Ile Ala Val Val Asn 145 150 155 160 Gly Trp Ala Ala Gly Gly Gly His Ser Leu His Val Val Cys Asp Leu 165 170 175 Thr Ile Ala Ser Arg Gln Glu Ala Arg Phe Lys Gln Thr Asp Ala Asp 180 185 190 Val Gly Ser Phe Asp Ala Gly Tyr Gly Ser Ala Tyr Leu Ala Lys Met 195 200 205 Val Gly Gln Lys Asn Ala Arg Glu Ile Phe Phe Leu Gly Arg Thr Tyr 210 215 220 Asp Ala Glu Arg Met Gln Gln Met Gly Ala Val Asn Ile Val Ala Asp 225 230 235 240 His Gly Asp Leu Glu Lys Glu Ala Ile Gln Ala Ala Arg Glu Ile Asn 245 250 255 Thr Lys Ser Pro Thr Gly Gln Arg Met Leu Lys Phe Ala Phe Asn Leu 260 265 270 Thr Asp Asp Gly Leu Met Gly Gln Gln Val Phe Ala Gly Glu Ala Thr 275 280 285 Arg Leu Ala Tyr Met Thr Asp Glu Ala Val Glu Gly Lys Glu Ala Phe 290 295 300 Leu Glu Lys Arg Glu Pro Asn Trp Asn Glu Phe Pro Tyr Tyr Tyr 305 310 315 <210> 499 <211> 384 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(361) <223> RXS02908 <400> 499 gccaacgagg gttggtttac cacctctgat tcaggtgaac tccacgacgg gattctcacc 60 gtgactggtc gcgtggatac ccgtcattga ttccggtgga ttg aag ttg cac cca 115 Leu Lys Leu His Pro 1 5 gag gta ctg gaa cgt gcc atc gca gat att aaa ggt gtc acc gcg gcg 163 Glu Val Leu Glu Arg Ala Ile Ala Asp Ile Lys Gly Val Thr Ala Ala 10 15 20 tgt gtt gtg ggt att ccc gat ccc cga tta ggc caa gca att gtg gcc 211 Cys Val Val Gly Ile Pro Asp Pro Arg Leu Gly Gln Ala Ile Val Ala 25 30 35 gcg tac tcc gga tcg atc agt ccg tct gaa gtt att gaa ggc ctc gac 259 Ala Tyr Ser Gly Ser Ile Ser Pro Ser Glu Val Ile Glu Gly Leu Asp 40 45 50 gat cta cct cgt tgg cag ctt ccc aaa cgg ctg aag cat ctg gaa tct 307 Asp Leu Pro Arg Trp Gln Leu Pro Lys Arg Leu Lys His Leu Glu Ser 55 60 65 ttg ccc agc att ggt cct gga aaa gct gat cga cgt gct atc gcg aag 355 Leu Pro Ser Ile Gly Pro Gly Lys Ala Asp Arg Arg Ala Ile Ala Lys 70 75 80 85 ctg ttt tagtcttcat tcttgctggc tgc 384 Leu Phe <210> 500 <211> 87 <212> PRT <213> Corynebacterium glutamicum <400> 500 Leu Lys Leu His Pro Glu Val Leu Glu Arg Ala Ile Ala Asp Ile Lys 1 5 10 15 Gly Val Thr Ala Ala Cys Val Val Gly Ile Pro Asp Pro Arg Leu Gly 20 25 30 Gln Ala Ile Val Ala Ala Tyr Ser Gly Ser Ile Ser Pro Ser Glu Val 35 40 45 Ile Glu Gly Leu Asp Asp Leu Pro Arg Trp Gln Leu Pro Lys Arg Leu 50 55 60 Lys His Leu Glu Ser Leu Pro Ser Ile Gly Pro Gly Lys Ala Asp Arg 65 70 75 80 Arg Ala Ile Ala Lys Leu Phe 85 <210> 501 <211> 775 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(775) <223> RXS03003 <400> 501 tcgatgatct gggctcccca ggtggtgcgg ctaagcttgg accacaagat tttgatcacc 60 caatgatcgc tgcgctgccg cctcaggcat aatctaacgc atg acc tct cgc acc 115 Met Thr Ser Arg Thr 1 5 ccg ctt gtt tct gtt ctt cct gat ttt ccg tgg gat tcg ctc gct tcc 163 Pro Leu Val Ser Val Leu Pro Asp Phe Pro Trp Asp Ser Leu Ala Ser 10 15 20 gca aaa gcc aaa gct gcg tct cac ccg gat ggg atc gtg aat ctt tct 211 Ala Lys Ala Lys Ala Ala Ser His Pro Asp Gly Ile Val Asn Leu Ser 25 30 35 gtt ggc act ccg gtt gat ccg gtc gcg ccc agc att cag atc gcg ttg 259 Val Gly Thr Pro Val Asp Pro Val Ala Pro Ser Ile Gln Ile Ala Leu 40 45 50 gca gaa gca gcg ggg ttt tcg ggt tac cct caa acc atc ggc acc ccg 307 Ala Glu Ala Ala Gly Phe Ser Gly Tyr Pro Gln Thr Ile Gly Thr Pro 55 60 65 gaa ctc cgc gca gcc atc agg ggc gcg ctt gag cgg cgc tac aac atg 355 Glu Leu Arg Ala Ala Ile Arg Gly Ala Leu Glu Arg Arg Tyr Asn Met 70 75 80 85 aca aag ctt gtc gac gcc tcc ctc ctc ccc gtc gtg ggt acc aag gag 403 Thr Lys Leu Val Asp Ala Ser Leu Leu Pro Val Val Gly Thr Lys Glu 90 95 100 gca att gcc ctt ctt cca ttc gcg ttg ggt att tcc ggc acc gtt gtc 451 Ala Ile Ala Leu Leu Pro Phe Ala Leu Gly Ile Ser Gly Thr Val Val 105 110 115 atc cca gag att gcg tac cca acc tac gaa gtc gct gtc gtg gcc gca 499 Ile Pro Glu Ile Ala Tyr Pro Thr Tyr Glu Val Ala Val Val Ala Ala 120 125 130 gga tgc acc gtg ttg cgt tct gat tcg ctg ttt aag ctc ggc ccg cag 547 Gly Cys Thr Val Leu Arg Ser Asp Ser Leu Phe Lys Leu Gly Pro Gln 135 140 145 atc ccg tcg atg atg ttt atc aac tca cca tcc aac ccc aca ggc aag 595 Ile Pro Ser Met Met Phe Ile Asn Ser Pro Ser Asn Pro Thr Gly Lys 150 155 160 165 gtt ctg ggc atc cca cac ttg cgc aag gtt gtg aag tgg gcg cag gaa 643 Val Leu Gly Ile Pro His Leu Arg Lys Val Val Lys Trp Ala Gln Glu 170 175 180 aac aac gtg atc ctc gca gct gat gaa tgc tac ttg ggt ctt ggc tgg 691 Asn Asn Val Ile Leu Ala Ala Asp Glu Cys Tyr Leu Gly Leu Gly Trp 185 190 195 gac gat gaa aac cca ccg atc tca att ttg gat cca cgt gtc tgc gat 739 Asp Asp Glu Asn Pro Pro Ile Ser Ile Leu Asp Pro Arg Val Cys Asp 200 205 210 ggc gac cac acc aac ttg atc gcc att cac tcg ctg 775 Gly Asp His Thr Asn Leu Ile Ala Ile His Ser Leu 215 220 225 <210> 502 <211> 225 <212> PRT <213> Corynebacterium glutamicum <400> 502 Met Thr Ser Arg Thr Pro Leu Val Ser Val Leu Pro Asp Phe Pro Trp 1 5 10 15 Asp Ser Leu Ala Ser Ala Lys Ala Lys Ala Ala Ser His Pro Asp Gly 20 25 30 Ile Val Asn Leu Ser Val Gly Thr Pro Val Asp Pro Val Ala Pro Ser 35 40 45 Ile Gln Ile Ala Leu Ala Glu Ala Ala Gly Phe Ser Gly Tyr Pro Gln 50 55 60 Thr Ile Gly Thr Pro Glu Leu Arg Ala Ala Ile Arg Gly Ala Leu Glu 65 70 75 80 Arg Arg Tyr Asn Met Thr Lys Leu Val Asp Ala Ser Leu Leu Pro Val 85 90 95 Val Gly Thr Lys Glu Ala Ile Ala Leu Leu Pro Phe Ala Leu Gly Ile 100 105 110 Ser Gly Thr Val Val Ile Pro Glu Ile Ala Tyr Pro Thr Tyr Glu Val 115 120 125 Ala Val Val Ala Ala Gly Cys Thr Val Leu Arg Ser Asp Ser Leu Phe 130 135 140 Lys Leu Gly Pro Gln Ile Pro Ser Met Met Phe Ile Asn Ser Pro Ser 145 150 155 160 Asn Pro Thr Gly Lys Val Leu Gly Ile Pro His Leu Arg Lys Val Val 165 170 175 Lys Trp Ala Gln Glu Asn Asn Val Ile Leu Ala Ala Asp Glu Cys Tyr 180 185 190 Leu Gly Leu Gly Trp Asp Asp Glu Asn Pro Pro Ile Ser Ile Leu Asp 195 200 205 Pro Arg Val Cys Asp Gly Asp His Thr Asn Leu Ile Ala Ile His Ser 210 215 220 Leu 225 <210> 503 <211> 390 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(367) <223> RXS03026 <400> 503 gttggcggcg cagtatcgtg aggtgcggga cctcgagcgg ggaatcccaa actagcatcc 60 cgaactagcc ccccaacaac aattagaaat ggaacctaaa atg cct gga aaa att 115 Met Pro Gly Lys Ile 1 5 ctc ctt ctc aac ggc cca aac ctg aac atg ctg ggc aaa cgc gag cct 163 Leu Leu Leu Asn Gly Pro Asn Leu Asn Met Leu Gly Lys Arg Glu Pro 10 15 20 gac att tac gga cac gac acc ttg gaa gac gtc gtc gcg ctg gca acc 211 Asp Ile Tyr Gly His Asp Thr Leu Glu Asp Val Val Ala Leu Ala Thr 25 30 35 gct gag gct gcg aaa cac ggc ctt gag gtt gag gcg ctg cag agc aat 259 Ala Glu Ala Ala Lys His Gly Leu Glu Val Glu Ala Leu Gln Ser Asn 40 45 50 cac caa ggt gag cta atc gat gcg ctg cac aac gct cgc ggg acc cac 307 His Gln Gly Glu Leu Ile Asp Ala Leu His Asn Ala Arg Gly Thr His 55 60 65 atc ggt tgc gtg att aac ccc ggc ggc ctg act aca ctt cgg tgg cgc 355 Ile Gly Cys Val Ile Asn Pro Gly Gly Leu Thr Thr Leu Arg Trp Arg 70 75 80 85 ttt tgg atg ctg tgaaggcgtc tgagcttcct acc 390 Phe Trp Met Leu <210> 504 <211> 89 <212> PRT <213> Corynebacterium glutamicum <400> 504 Met Pro Gly Lys Ile Leu Leu Leu Asn Gly Pro Asn Leu Asn Met Leu 1 5 10 15 Gly Lys Arg Glu Pro Asp Ile Tyr Gly His Asp Thr Leu Glu Asp Val 20 25 30 Val Ala Leu Ala Thr Ala Glu Ala Ala Lys His Gly Leu Glu Val Glu 35 40 45 Ala Leu Gln Ser Asn His Gln Gly Glu Leu Ile Asp Ala Leu His Asn 50 55 60 Ala Arg Gly Thr His Ile Gly Cys Val Ile Asn Pro Gly Gly Leu Thr 65 70 75 80 Thr Leu Arg Trp Arg Phe Trp Met Leu 85 <210> 505 <211> 621 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(598) <223> RXS03074 <400> 505 tttgtgggca atctggtttt ttcgtaattg tgtgggatga atctcttaaa aattcacatt 60 tagcaggaca agcatactgt tttagttcta tgctgtgggc atg act caa agt gct 115 Met Thr Gln Ser Ala 1 5 cca gaa ttc att gcc acc gca gac ctc gta gac atc atc ggc gac aac 163 Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp Ile Ile Gly Asp Asn 10 15 20 gcg caa tca tgc gac act cag ttt caa aac ctt gga ggt gcc aca gaa 211 Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu Gly Gly Ala Thr Glu 25 30 35 ttc cac gga ata ata acc acc gtg aaa tgc ttc caa gac aac gcc ctc 259 Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe Gln Asp Asn Ala Leu 40 45 50 ctg aaa tcc atc ctg agc gag gat aat cct ggg gga gtg ctg gtt atc 307 Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly Gly Val Leu Val Ile 55 60 65 gat ggc gac gca tcc gtg cac acc gcg cta gtt ggc gac atc att gca 355 Asp Gly Asp Ala Ser Val His Thr Ala Leu Val Gly Asp Ile Ile Ala 70 75 80 85 gga ctt gga aaa gat cat ggt tgg tcc gga gta att gtc aac gga gca 403 Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val Ile Val Asn Gly Ala 90 95 100 att cga gac tcc gca gtc atc ggc acc atg acc ttt ggt tgt aaa gcc 451 Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr Phe Gly Cys Lys Ala 105 110 115 ctt gga acc aac ccg cgg aaa tcc act aaa act ggt tcc ggc gaa cga 499 Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr Gly Ser Gly Glu Arg 120 125 130 gac gta gtg gta tcg att ggt ggc att gac ttc att cct ggt cat tac 547 Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe Ile Pro Gly His Tyr 135 140 145 gtc tac gcg gac tct gac gga att atc gtc acc gag gcg cca att aag 595 Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr Glu Ala Pro Ile Lys 150 155 160 165 cag taatttgttt tgacgacgca gta 621 Gln <210> 506 <211> 166 <212> PRT <213> Corynebacterium glutamicum <400> 506 Met Thr Gln Ser Ala Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp 1 5 10 15 Ile Ile Gly Asp Asn Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu 20 25 30 Gly Gly Ala Thr Glu Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe 35 40 45 Gln Asp Asn Ala Leu Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly 50 55 60 Gly Val Leu Val Ile Asp Gly Asp Ala Ser Val His Thr Ala Leu Val 65 70 75 80 Gly Asp Ile Ile Ala Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val 85 90 95 Ile Val Asn Gly Ala Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr 100 105 110 Phe Gly Cys Lys Ala Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr 115 120 125 Gly Ser Gly Glu Arg Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe 130 135 140 Ile Pro Gly His Tyr Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr 145 150 155 160 Glu Ala Pro Ile Lys Gln 165 <210> 507 <211> 3075 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3052) <223> RXC01434 <400> 507 ggtttcctgc gcaccgtgat gattggtgcg gcgctgtcgc cggccatcgc ttcggcgttc 60 aacactgcca acacgctgcc caacctgatc actggaaatc gtg ttg ggt gcg gtg 115 Val Leu Gly Ala Val 1 5 ctg aca tcg ctg gtt att ccg gtc ctt acc cgc gcg gaa aaa gaa gac 163 Leu Thr Ser Leu Val Ile Pro Val Leu Thr Arg Ala Glu Lys Glu Asp 10 15 20 gcc gac ggc ggt tcc ggg ttc ttc agg cgg ctg ctc acc ctg tcg gtg 211 Ala Asp Gly Gly Ser Gly Phe Phe Arg Arg Leu Leu Thr Leu Ser Val 25 30 35 acg ctg ctg ggt ggt gtc acc atc ctg tcg att atc ggc gcg ccg ctg 259 Thr Leu Leu Gly Gly Val Thr Ile Leu Ser Ile Ile Gly Ala Pro Leu 40 45 50 ctg aca cgg atg atg ctg tcc tct gag gga caa gtc aac gtg gtc atg 307 Leu Thr Arg Met Met Leu Ser Ser Glu Gly Gln Val Asn Val Val Met 55 60 65 tcc acg gcc ttt gcg tat tgg ctg ctg cca cag att ttc ttc tac ggc 355 Ser Thr Ala Phe Ala Tyr Trp Leu Leu Pro Gln Ile Phe Phe Tyr Gly 70 75 80 85 ctg ttt gcc ctg ttc atg gct gtg ttg aac acc cgt gaa gtg ttc aaa 403 Leu Phe Ala Leu Phe Met Ala Val Leu Asn Thr Arg Glu Val Phe Lys 90 95 100 ccc ggc gcg tgg gca cct gtt gtc aac aat gtg atc acc ttg acc gtg 451 Pro Gly Ala Trp Ala Pro Val Val Asn Asn Val Ile Thr Leu Thr Val 105 110 115 ctg ggc gtg tac atg gtg ctg cct gcg cgt ttg cac ccg cat gag cag 499 Leu Gly Val Tyr Met Val Leu Pro Ala Arg Leu His Pro His Glu Gln 120 125 130 gtg ggc att ttt gat ccg cag atc att ttc ctc ggc gtg ggc acc acc 547 Val Gly Ile Phe Asp Pro Gln Ile Ile Phe Leu Gly Val Gly Thr Thr 135 140 145 ctt ggt gtg gtt gca cag tgt cta atc atg att ccg tac ctg cgt cgc 595 Leu Gly Val Val Ala Gln Cys Leu Ile Met Ile Pro Tyr Leu Arg Arg 150 155 160 165 gcg ggc att gat atg cgc cct ctg tgg ggt atc gat gcg cgt ttg aag 643 Ala Gly Ile Asp Met Arg Pro Leu Trp Gly Ile Asp Ala Arg Leu Lys 170 175 180 caa ttc ggt ggc atg gcg atg gcg atc atc gtg tac gtg gca atc tcc 691 Gln Phe Gly Gly Met Ala Met Ala Ile Ile Val Tyr Val Ala Ile Ser 185 190 195 cag ttc ggt tac atc atc acc act cgc att gcg tcg att gca gac gat 739 Gln Phe Gly Tyr Ile Ile Thr Thr Arg Ile Ala Ser Ile Ala Asp Asp 200 205 210 gct gcg ccg ttt att tat cag cag cac tgg atg ttg ctg caa gtt cct 787 Ala Ala Pro Phe Ile Tyr Gln Gln His Trp Met Leu Leu Gln Val Pro 215 220 225 tat ggc atc atc ggc gtc acc ttg ctc acc gcg att atg ccg cga ctg 835 Tyr Gly Ile Ile Gly Val Thr Leu Leu Thr Ala Ile Met Pro Arg Leu 230 235 240 245 tcc cgc aac gcg gca gac ggc gat gat agg gca gta gtc tct gac ctt 883 Ser Arg Asn Ala Ala Asp Gly Asp Asp Arg Ala Val Val Ser Asp Leu 250 255 260 cag ttg ggt tcc aag cta acc ttc atc gca ctg atc ccc atc gtg gtg 931 Gln Leu Gly Ser Lys Leu Thr Phe Ile Ala Leu Ile Pro Ile Val Val 265 270 275 ttc ttc acc gcc ttc ggt gtc cct att gcc aat ggc ctt ttt gcc tac 979 Phe Phe Thr Ala Phe Gly Val Pro Ile Ala Asn Gly Leu Phe Ala Tyr 280 285 290 ggc caa ttc gat gcc aac gcc gcc aac atc ctt ggt tgg act ctg agc 1027 Gly Gln Phe Asp Ala Asn Ala Ala Asn Ile Leu Gly Trp Thr Leu Ser 295 300 305 ttc tct gct ttc acg ctg att cct tac gct ttg gtg ctg cta cat ctg 1075 Phe Ser Ala Phe Thr Leu Ile Pro Tyr Ala Leu Val Leu Leu His Leu 310 315 320 325 cgt gtg ttt tat gcg cgt gaa gag gtc tgg acc cca acc ttc atc atc 1123 Arg Val Phe Tyr Ala Arg Glu Glu Val Trp Thr Pro Thr Phe Ile Ile 330 335 340 gcc ggc atc acc gcc acc aag gtc gtg ctt tcc ctg ttg gca ccg ctg 1171 Ala Gly Ile Thr Ala Thr Lys Val Val Leu Ser Leu Leu Ala Pro Leu 345 350 355 ctg tcg agc tcc ccg gag cgt gtg gtg gtg ctt ctt ggt gcg gcc aac 1219 Leu Ser Ser Ser Pro Glu Arg Val Val Val Leu Leu Gly Ala Ala Asn 360 365 370 ggt ttc agt ttc atc acc ggc gcg gtc atc ggc gcg tat ctg ttg cgc 1267 Gly Phe Ser Phe Ile Thr Gly Ala Val Ile Gly Ala Tyr Leu Leu Arg 375 380 385 aac aaa ctc ggc ctg ttg ggt atg cgc tct ttg gct aaa acc tcc ctg 1315 Asn Lys Leu Gly Leu Leu Gly Met Arg Ser Leu Ala Lys Thr Ser Leu 390 395 400 405 tgg gcg ttg ggc tct gcg gcg gtt ggt gca gca gca gca tgg gcg ttg 1363 Trp Ala Leu Gly Ser Ala Ala Val Gly Ala Ala Ala Ala Trp Ala Leu 410 415 420 ggg tgg ctg att caa gcc gtc gtg ggc gat ttc ttg ctg ggc act cta 1411 Gly Trp Leu Ile Gln Ala Val Val Gly Asp Phe Leu Leu Gly Thr Leu 425 430 435 agc tcc gta ggc tac ttg ttg aac ctg gct gtg ttg ggt gtc ttc ttc 1459 Ser Ser Val Gly Tyr Leu Leu Asn Leu Ala Val Leu Gly Val Phe Phe 440 445 450 atc ttc gtc acc ggc atc gtg ttg tca cgt tct ggt ttg ccg gag gtc 1507 Ile Phe Val Thr Gly Ile Val Leu Ser Arg Ser Gly Leu Pro Glu Val 455 460 465 caa aac ttg ggc cag gca ctg acc cgc atc cca ggt ttg agc cgg ttt 1555 Gln Asn Leu Gly Gln Ala Leu Thr Arg Ile Pro Gly Leu Ser Arg Phe 470 475 480 485 att cgc ccg aat acc aag atc tct ttg gat gtc ggc gaa gtc tcc gag 1603 Ile Arg Pro Asn Thr Lys Ile Ser Leu Asp Val Gly Glu Val Ser Glu 490 495 500 cag gat ttc tcc acc cag ctg gtc gcg cca agc gag ttc gca gca acc 1651 Gln Asp Phe Ser Thr Gln Leu Val Ala Pro Ser Glu Phe Ala Ala Thr 505 510 515 cct gtg ccg cca ccg atg tcc gcc ggt att gtc cgc gga cct cgc ctg 1699 Pro Val Pro Pro Pro Met Ser Ala Gly Ile Val Arg Gly Pro Arg Leu 520 525 530 gtt ccc ggc gcc cca gtc ggc gac ggt cgt ttc cgt ctg ctc gcc gat 1747 Val Pro Gly Ala Pro Val Gly Asp Gly Arg Phe Arg Leu Leu Ala Asp 535 540 545 cac ggc ggc gtc caa ggc gcg cgt ttc tgg cag gcc cgc gag atc gcc 1795 His Gly Gly Val Gln Gly Ala Arg Phe Trp Gln Ala Arg Glu Ile Ala 550 555 560 565 acc ggc aag gaa gtc gcg ctg atc ttt gtg gat act tcc ggc aac gcc 1843 Thr Gly Lys Glu Val Ala Leu Ile Phe Val Asp Thr Ser Gly Asn Ala 570 575 580 cca ttt gcg cca ctg tct tcg gca gcc gca gcg ggc atc gcc tac gag 1891 Pro Phe Ala Pro Leu Ser Ser Ala Ala Ala Ala Gly Ile Ala Tyr Glu 585 590 595 gtg cag cgc cgc acc aag aag ctg gcc agc ttg ggc agc ttg gcg gta 1939 Val Gln Arg Arg Thr Lys Lys Leu Ala Ser Leu Gly Ser Leu Ala Val 600 605 610 gcc ccc aac atc cac tcc gag gcg tac cgc aac ggt tgc ctc att gtg 1987 Ala Pro Asn Ile His Ser Glu Ala Tyr Arg Asn Gly Cys Leu Ile Val 615 620 625 gcc gat tgg gtg cct ggc tcc agc ttg agc gcc gtc gcg gaa tcc ggt 2035 Ala Asp Trp Val Pro Gly Ser Ser Leu Ser Ala Val Ala Glu Ser Gly 630 635 640 645 gcc gat ccc cgc gcc gcc gcg ttc gcg ctc gcg gaa cta act gaa acc 2083 Ala Asp Pro Arg Ala Ala Ala Phe Ala Leu Ala Glu Leu Thr Glu Thr 650 655 660 atc ggc gag gcc cac gag atg ggt atc ccg gcc ggc ttg gac aac aag 2131 Ile Gly Glu Ala His Glu Met Gly Ile Pro Ala Gly Leu Asp Asn Lys 665 670 675 tgc cga att cgt atc aac acc gac ggc cat gcc gtc ctc gcc ttg ccg 2179 Cys Arg Ile Arg Ile Asn Thr Asp Gly His Ala Val Leu Ala Leu Pro 680 685 690 gcg att ttg ccc gat gcc tca gag ctc cgc gac gcc aag tcc ctg gcc 2227 Ala Ile Leu Pro Asp Ala Ser Glu Leu Arg Asp Ala Lys Ser Leu Ala 695 700 705 tcg gcc gcc gag atg ctt atc gac gcg acc ctc gct ccc agc gac gtc 2275 Ser Ala Ala Glu Met Leu Ile Asp Ala Thr Leu Ala Pro Ser Asp Val 710 715 720 725 aag gca atg gtc act gaa gcc cag ggg cta gct aca gaa gac aat ccc 2323 Lys Ala Met Val Thr Glu Ala Gln Gly Leu Ala Thr Glu Asp Asn Pro 730 735 740 gat tac gca tca ctt gcc atg gcg atg cgc acc tgc gga ctg ttc acc 2371 Asp Tyr Ala Ser Leu Ala Met Ala Met Arg Thr Cys Gly Leu Phe Thr 745 750 755 gag gaa cca acc cac ctt gtg gtg aag aag gaa aag aca cca aag cct 2419 Glu Glu Pro Thr His Leu Val Val Lys Lys Glu Lys Thr Pro Lys Pro 760 765 770 gcg aca cgt gat ggt ttc ggt gcc tcc gac tac acc gtc aag ggc atg 2467 Ala Thr Arg Asp Gly Phe Gly Ala Ser Asp Tyr Thr Val Lys Gly Met 775 780 785 gca gcc atc gcc gct gtg gtg atc atc ttg gtt tcc ctg gtg gcc gcc 2515 Ala Ala Ile Ala Ala Val Val Ile Ile Leu Val Ser Leu Val Ala Ala 790 795 800 805 ggt acc gcg ttc ctc acc agc ttc ttc ggc agc agc acc aac gaa caa 2563 Gly Thr Ala Phe Leu Thr Ser Phe Phe Gly Ser Ser Thr Asn Glu Gln 810 815 820 tcc ccg ttg gcc tct gtt gaa gcc acc acc tct gca aca cca gaa cct 2611 Ser Pro Leu Ala Ser Val Glu Ala Thr Thr Ser Ala Thr Pro Glu Pro 825 830 835 gtg ggg cca ccg gtc tac ctg gat ctg gat caa gcc cgc acg tgg gat 2659 Val Gly Pro Pro Val Tyr Leu Asp Leu Asp Gln Ala Arg Thr Trp Asp 840 845 850 gac ggt gca gga aca gat gtc acc gac gtc acc gac ggc aac acc tcc 2707 Asp Gly Ala Gly Thr Asp Val Thr Asp Val Thr Asp Gly Asn Thr Ser 855 860 865 acc gca tgg acc tcc acc ggc ggc gac ggc ctc cta gtt gac ctg tcc 2755 Thr Ala Trp Thr Ser Thr Gly Gly Asp Gly Leu Leu Val Asp Leu Ser 870 875 880 885 acg cct gcc cgc ctc gac cgc gtc atc ttg acc acc ggc acc ggc tcc 2803 Thr Pro Ala Arg Leu Asp Arg Val Ile Leu Thr Thr Gly Thr Gly Ser 890 895 900 gac agc aac gtg acc tcg acc gtg aag atc tac gca ttc aac gac gcc 2851 Asp Ser Asn Val Thr Ser Thr Val Lys Ile Tyr Ala Phe Asn Asp Ala 905 910 915 tca cca cac tcc ctg tcg gaa ggc atc gag atc ggc acc gtg gat tat 2899 Ser Pro His Ser Leu Ser Glu Gly Ile Glu Ile Gly Thr Val Asp Tyr 920 925 930 tcc ggc cgc agt ctc agc cac agc atc cgc gat tcc tcc aag ctt ccg 2947 Ser Gly Arg Ser Leu Ser His Ser Ile Arg Asp Ser Ser Lys Leu Pro 935 940 945 ggt cag gtg gaa tcc gtg gtg att ctg gtc gat gag gtt cgt tcc tca 2995 Gly Gln Val Glu Ser Val Val Ile Leu Val Asp Glu Val Arg Ser Ser 950 955 960 965 caa acc tca gac acc aat cca cag atg cag atc gct gaa gta caa ctt 3043 Gln Thr Ser Asp Thr Asn Pro Gln Met Gln Ile Ala Glu Val Gln Leu 970 975 980 gtt ggt tgg taaattacgc gtttgtgatt gac 3075 Val Gly Trp <210> 508 <211> 984 <212> PRT <213> Corynebacterium glutamicum <400> 508 Val Leu Gly Ala Val Leu Thr Ser Leu Val Ile Pro Val Leu Thr Arg 1 5 10 15 Ala Glu Lys Glu Asp Ala Asp Gly Gly Ser Gly Phe Phe Arg Arg Leu 20 25 30 Leu Thr Leu Ser Val Thr Leu Leu Gly Gly Val Thr Ile Leu Ser Ile 35 40 45 Ile Gly Ala Pro Leu Leu Thr Arg Met Met Leu Ser Ser Glu Gly Gln 50 55 60 Val Asn Val Val Met Ser Thr Ala Phe Ala Tyr Trp Leu Leu Pro Gln 65 70 75 80 Ile Phe Phe Tyr Gly Leu Phe Ala Leu Phe Met Ala Val Leu Asn Thr 85 90 95 Arg Glu Val Phe Lys Pro Gly Ala Trp Ala Pro Val Val Asn Asn Val 100 105 110 Ile Thr Leu Thr Val Leu Gly Val Tyr Met Val Leu Pro Ala Arg Leu 115 120 125 His Pro His Glu Gln Val Gly Ile Phe Asp Pro Gln Ile Ile Phe Leu 130 135 140 Gly Val Gly Thr Thr Leu Gly Val Val Ala Gln Cys Leu Ile Met Ile 145 150 155 160 Pro Tyr Leu Arg Arg Ala Gly Ile Asp Met Arg Pro Leu Trp Gly Ile 165 170 175 Asp Ala Arg Leu Lys Gln Phe Gly Gly Met Ala Met Ala Ile Ile Val 180 185 190 Tyr Val Ala Ile Ser Gln Phe Gly Tyr Ile Ile Thr Thr Arg Ile Ala 195 200 205 Ser Ile Ala Asp Asp Ala Ala Pro Phe Ile Tyr Gln Gln His Trp Met 210 215 220 Leu Leu Gln Val Pro Tyr Gly Ile Ile Gly Val Thr Leu Leu Thr Ala 225 230 235 240 Ile Met Pro Arg Leu Ser Arg Asn Ala Ala Asp Gly Asp Asp Arg Ala 245 250 255 Val Val Ser Asp Leu Gln Leu Gly Ser Lys Leu Thr Phe Ile Ala Leu 260 265 270 Ile Pro Ile Val Val Phe Phe Thr Ala Phe Gly Val Pro Ile Ala Asn 275 280 285 Gly Leu Phe Ala Tyr Gly Gln Phe Asp Ala Asn Ala Ala Asn Ile Leu 290 295 300 Gly Trp Thr Leu Ser Phe Ser Ala Phe Thr Leu Ile Pro Tyr Ala Leu 305 310 315 320 Val Leu Leu His Leu Arg Val Phe Tyr Ala Arg Glu Glu Val Trp Thr 325 330 335 Pro Thr Phe Ile Ile Ala Gly Ile Thr Ala Thr Lys Val Val Leu Ser 340 345 350 Leu Leu Ala Pro Leu Leu Ser Ser Ser Pro Glu Arg Val Val Val Leu 355 360 365 Leu Gly Ala Ala Asn Gly Phe Ser Phe Ile Thr Gly Ala Val Ile Gly 370 375 380 Ala Tyr Leu Leu Arg Asn Lys Leu Gly Leu Leu Gly Met Arg Ser Leu 385 390 395 400 Ala Lys Thr Ser Leu Trp Ala Leu Gly Ser Ala Ala Val Gly Ala Ala 405 410 415 Ala Ala Trp Ala Leu Gly Trp Leu Ile Gln Ala Val Val Gly Asp Phe 420 425 430 Leu Leu Gly Thr Leu Ser Ser Val Gly Tyr Leu Leu Asn Leu Ala Val 435 440 445 Leu Gly Val Phe Phe Ile Phe Val Thr Gly Ile Val Leu Ser Arg Ser 450 455 460 Gly Leu Pro Glu Val Gln Asn Leu Gly Gln Ala Leu Thr Arg Ile Pro 465 470 475 480 Gly Leu Ser Arg Phe Ile Arg Pro Asn Thr Lys Ile Ser Leu Asp Val 485 490 495 Gly Glu Val Ser Glu Gln Asp Phe Ser Thr Gln Leu Val Ala Pro Ser 500 505 510 Glu Phe Ala Ala Thr Pro Val Pro Pro Pro Met Ser Ala Gly Ile Val 515 520 525 Arg Gly Pro Arg Leu Val Pro Gly Ala Pro Val Gly Asp Gly Arg Phe 530 535 540 Arg Leu Leu Ala Asp His Gly Gly Val Gln Gly Ala Arg Phe Trp Gln 545 550 555 560 Ala Arg Glu Ile Ala Thr Gly Lys Glu Val Ala Leu Ile Phe Val Asp 565 570 575 Thr Ser Gly Asn Ala Pro Phe Ala Pro Leu Ser Ser Ala Ala Ala Ala 580 585 590 Gly Ile Ala Tyr Glu Val Gln Arg Arg Thr Lys Lys Leu Ala Ser Leu 595 600 605 Gly Ser Leu Ala Val Ala Pro Asn Ile His Ser Glu Ala Tyr Arg Asn 610 615 620 Gly Cys Leu Ile Val Ala Asp Trp Val Pro Gly Ser Ser Leu Ser Ala 625 630 635 640 Val Ala Glu Ser Gly Ala Asp Pro Arg Ala Ala Ala Phe Ala Leu Ala 645 650 655 Glu Leu Thr Glu Thr Ile Gly Glu Ala His Glu Met Gly Ile Pro Ala 660 665 670 Gly Leu Asp Asn Lys Cys Arg Ile Arg Ile Asn Thr Asp Gly His Ala 675 680 685 Val Leu Ala Leu Pro Ala Ile Leu Pro Asp Ala Ser Glu Leu Arg Asp 690 695 700 Ala Lys Ser Leu Ala Ser Ala Ala Glu Met Leu Ile Asp Ala Thr Leu 705 710 715 720 Ala Pro Ser Asp Val Lys Ala Met Val Thr Glu Ala Gln Gly Leu Ala 725 730 735 Thr Glu Asp Asn Pro Asp Tyr Ala Ser Leu Ala Met Ala Met Arg Thr 740 745 750 Cys Gly Leu Phe Thr Glu Glu Pro Thr His Leu Val Val Lys Lys Glu 755 760 765 Lys Thr Pro Lys Pro Ala Thr Arg Asp Gly Phe Gly Ala Ser Asp Tyr 770 775 780 Thr Val Lys Gly Met Ala Ala Ile Ala Ala Val Val Ile Ile Leu Val 785 790 795 800 Ser Leu Val Ala Ala Gly Thr Ala Phe Leu Thr Ser Phe Phe Gly Ser 805 810 815 Ser Thr Asn Glu Gln Ser Pro Leu Ala Ser Val Glu Ala Thr Thr Ser 820 825 830 Ala Thr Pro Glu Pro Val Gly Pro Pro Val Tyr Leu Asp Leu Asp Gln 835 840 845 Ala Arg Thr Trp Asp Asp Gly Ala Gly Thr Asp Val Thr Asp Val Thr 850 855 860 Asp Gly Asn Thr Ser Thr Ala Trp Thr Ser Thr Gly Gly Asp Gly Leu 865 870 875 880 Leu Val Asp Leu Ser Thr Pro Ala Arg Leu Asp Arg Val Ile Leu Thr 885 890 895 Thr Gly Thr Gly Ser Asp Ser Asn Val Thr Ser Thr Val Lys Ile Tyr 900 905 910 Ala Phe Asn Asp Ala Ser Pro His Ser Leu Ser Glu Gly Ile Glu Ile 915 920 925 Gly Thr Val Asp Tyr Ser Gly Arg Ser Leu Ser His Ser Ile Arg Asp 930 935 940 Ser Ser Lys Leu Pro Gly Gln Val Glu Ser Val Val Ile Leu Val Asp 945 950 955 960 Glu Val Arg Ser Ser Gln Thr Ser Asp Thr Asn Pro Gln Met Gln Ile 965 970 975 Ala Glu Val Gln Leu Val Gly Trp 980 <210> 509 <211> 930 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(907) <223> RXC02080 <400> 509 cgtaaattcg aagcgagctt ctaattctag caagcttggt gatggagtat cctgccaaaa 60 tttgtcctgt tgcttattgt gcaggaattc ggaggcggac atg tca atc gag tgg 115 Met Ser Ile Glu Trp 1 5 tta caa att gtt gaa tta gga gcg atc ttt ggt gca ggt ttc ctc gca 163 Leu Gln Ile Val Glu Leu Gly Ala Ile Phe Gly Ala Gly Phe Leu Ala 10 15 20 gga agc atc aat gta att gtc gga gca gga aca tta gtg tcg ttt cct 211 Gly Ser Ile Asn Val Ile Val Gly Ala Gly Thr Leu Val Ser Phe Pro 25 30 35 att ctc gtg ttc ctg ggc ctt cca ccg ttg act gcc acc atc gcc aac 259 Ile Leu Val Phe Leu Gly Leu Pro Pro Leu Thr Ala Thr Ile Ala Asn 40 45 50 acc atc ggc atc gtt cct gga agt att tcg ggt gtg gtt gct tat aga 307 Thr Ile Gly Ile Val Pro Gly Ser Ile Ser Gly Val Val Ala Tyr Arg 55 60 65 cgt gaa cta cac gcc cat gta aaa acc atc aga ttt ctg ctg cca gca 355 Arg Glu Leu His Ala His Val Lys Thr Ile Arg Phe Leu Leu Pro Ala 70 75 80 85 tca atc ctc gga ggg atc acc ggc gcc tcg ctc ttg ctg cat ttc tcc 403 Ser Ile Leu Gly Gly Ile Thr Gly Ala Ser Leu Leu Leu His Phe Ser 90 95 100 gca gat gtt ttt aca gca gta att ccc tgg ctg att gga ttc ggc acg 451 Ala Asp Val Phe Thr Ala Val Ile Pro Trp Leu Ile Gly Phe Gly Thr 105 110 115 ctg ttg gtt atc gca ggt cca tca att aag aag cat gtt ggc gct cat 499 Leu Leu Val Ile Ala Gly Pro Ser Ile Lys Lys His Val Gly Ala His 120 125 130 act tca ggt ggc atc tct gct ggg ttt agg caa ttg cct ttc ccg agc 547 Thr Ser Gly Gly Ile Ser Ala Gly Phe Arg Gln Leu Pro Phe Pro Ser 135 140 145 cga acc acc ttc atc gtc tca gta tgt ggt gcc ctg ttg ctg ggc atg 595 Arg Thr Thr Phe Ile Val Ser Val Cys Gly Ala Leu Leu Leu Gly Met 150 155 160 165 tat gga ggg tac ttc agc gca gct caa ggc att ctt ctc atc gca ttg 643 Tyr Gly Gly Tyr Phe Ser Ala Ala Gln Gly Ile Leu Leu Ile Ala Leu 170 175 180 ctt ggc atc aca tca acg ctg cag atg cag gaa ctc aac gcc atc aaa 691 Leu Gly Ile Thr Ser Thr Leu Gln Met Gln Glu Leu Asn Ala Ile Lys 185 190 195 aac ctc aca gtg gcg gca gtt aat ctc atc gca gcc agt gtt ttt ata 739 Asn Leu Thr Val Ala Ala Val Asn Leu Ile Ala Ala Ser Val Phe Ile 200 205 210 atc atc tcc cct gag ttg atc tcc tgg ccg acc gtt gcc tta atc gcg 787 Ile Ile Ser Pro Glu Leu Ile Ser Trp Pro Thr Val Ala Leu Ile Ala 215 220 225 ctt ggc tca gct tta ggt gga tac atc ggc gga cgg tac gcc cgc cga 835 Leu Gly Ser Ala Leu Gly Gly Tyr Ile Gly Gly Arg Tyr Ala Arg Arg 230 235 240 245 ctt cgc ccc agt gtt ttt aga gca ttt gtg gtc atc gtc gga atc acc 883 Leu Arg Pro Ser Val Phe Arg Ala Phe Val Val Ile Val Gly Ile Thr 250 255 260 acg gtc atc gtt atg acg atc ggt taatgcagca gactagtaac ccc 930 Thr Val Ile Val Met Thr Ile Gly 265 <210> 510 <211> 269 <212> PRT <213> Corynebacterium glutamicum <400> 510 Met Ser Ile Glu Trp Leu Gln Ile Val Glu Leu Gly Ala Ile Phe Gly 1 5 10 15 Ala Gly Phe Leu Ala Gly Ser Ile Asn Val Ile Val Gly Ala Gly Thr 20 25 30 Leu Val Ser Phe Pro Ile Leu Val Phe Leu Gly Leu Pro Pro Leu Thr 35 40 45 Ala Thr Ile Ala Asn Thr Ile Gly Ile Val Pro Gly Ser Ile Ser Gly 50 55 60 Val Val Ala Tyr Arg Arg Glu Leu His Ala His Val Lys Thr Ile Arg 65 70 75 80 Phe Leu Leu Pro Ala Ser Ile Leu Gly Gly Ile Thr Gly Ala Ser Leu 85 90 95 Leu Leu His Phe Ser Ala Asp Val Phe Thr Ala Val Ile Pro Trp Leu 100 105 110 Ile Gly Phe Gly Thr Leu Leu Val Ile Ala Gly Pro Ser Ile Lys Lys 115 120 125 His Val Gly Ala His Thr Ser Gly Gly Ile Ser Ala Gly Phe Arg Gln 130 135 140 Leu Pro Phe Pro Ser Arg Thr Thr Phe Ile Val Ser Val Cys Gly Ala 145 150 155 160 Leu Leu Leu Gly Met Tyr Gly Gly Tyr Phe Ser Ala Ala Gln Gly Ile 165 170 175 Leu Leu Ile Ala Leu Leu Gly Ile Thr Ser Thr Leu Gln Met Gln Glu 180 185 190 Leu Asn Ala Ile Lys Asn Leu Thr Val Ala Ala Val Asn Leu Ile Ala 195 200 205 Ala Ser Val Phe Ile Ile Ile Ser Pro Glu Leu Ile Ser Trp Pro Thr 210 215 220 Val Ala Leu Ile Ala Leu Gly Ser Ala Leu Gly Gly Tyr Ile Gly Gly 225 230 235 240 Arg Tyr Ala Arg Arg Leu Arg Pro Ser Val Phe Arg Ala Phe Val Val 245 250 255 Ile Val Gly Ile Thr Thr Val Ile Val Met Thr Ile Gly 260 265 <210> 511 <211> 669 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(646) <223> RXC02789 <400> 511 ttcttccgta cggctatgct taaaagctaa atttgtcttt gtgccttgca acacattaat 60 ttcttaacac taaacaatgg aaaggtaagc gggtttttct atg aag gtt tcc gcc 115 Met Lys Val Ser Ala 1 5 gat aca ccc ggt cac gat gat cca ggc cca ggc cgg cgc ctt ggc tta 163 Asp Thr Pro Gly His Asp Asp Pro Gly Pro Gly Arg Arg Leu Gly Leu 10 15 20 gat gtc ggc acc gtg cgc atc gga gtg gca gcc tct gac cgc gat gcc 211 Asp Val Gly Thr Val Arg Ile Gly Val Ala Ala Ser Asp Arg Asp Ala 25 30 35 aag ctt gcc atg cct gtg gaa acc gtt ccg cgg gaa act gga ttc aaa 259 Lys Leu Ala Met Pro Val Glu Thr Val Pro Arg Glu Thr Gly Phe Lys 40 45 50 ggg cca gac ctg gcc gat att gat cgg ttg gtc gcc atc gtt gag gaa 307 Gly Pro Asp Leu Ala Asp Ile Asp Arg Leu Val Ala Ile Val Glu Glu 55 60 65 tac aac gcc gtg gaa gtc att gtt ggt cta ccc aca gat ctg cag gga 355 Tyr Asn Ala Val Glu Val Ile Val Gly Leu Pro Thr Asp Leu Gln Gly 70 75 80 85 aat ggc tcc gcc agt gtg aag cat gca aag gaa att gct ttc cgc gtc 403 Asn Gly Ser Ala Ser Val Lys His Ala Lys Glu Ile Ala Phe Arg Val 90 95 100 cgt cgg cgc ctc acc aat gct gga aag aac att ccg gta cgg ctt ggc 451 Arg Arg Arg Leu Thr Asn Ala Gly Lys Asn Ile Pro Val Arg Leu Gly 105 110 115 gac gaa cgc ctc acc acc gtc gtg gcc acc caa gcc ttg cgg gcc tca 499 Asp Glu Arg Leu Thr Thr Val Val Ala Thr Gln Ala Leu Arg Ala Ser 120 125 130 gga gtc agc gaa aaa gcg gga cgt aaa gtt att gat caa gct gcc gca 547 Gly Val Ser Glu Lys Ala Gly Arg Lys Val Ile Asp Gln Ala Ala Ala 135 140 145 gta gaa atc ctt caa acc tgg ttg gat gct cgc acc cga gcc ctt gaa 595 Val Glu Ile Leu Gln Thr Trp Leu Asp Ala Arg Thr Arg Ala Leu Glu 150 155 160 165 cca caa tcc aca gac acc caa gat ttc gac gag aag gga aat ttc cca 643 Pro Gln Ser Thr Asp Thr Gln Asp Phe Asp Glu Lys Gly Asn Phe Pro 170 175 180 gga tgaaccaaat ccgaaaccgc cgg 669 Gly <210> 512 <211> 182 <212> PRT <213> Corynebacterium glutamicum <400> 512 Met Lys Val Ser Ala Asp Thr Pro Gly His Asp Asp Pro Gly Pro Gly 1 5 10 15 Arg Arg Leu Gly Leu Asp Val Gly Thr Val Arg Ile Gly Val Ala Ala 20 25 30 Ser Asp Arg Asp Ala Lys Leu Ala Met Pro Val Glu Thr Val Pro Arg 35 40 45 Glu Thr Gly Phe Lys Gly Pro Asp Leu Ala Asp Ile Asp Arg Leu Val 50 55 60 Ala Ile Val Glu Glu Tyr Asn Ala Val Glu Val Ile Val Gly Leu Pro 65 70 75 80 Thr Asp Leu Gln Gly Asn Gly Ser Ala Ser Val Lys His Ala Lys Glu 85 90 95 Ile Ala Phe Arg Val Arg Arg Arg Leu Thr Asn Ala Gly Lys Asn Ile 100 105 110 Pro Val Arg Leu Gly Asp Glu Arg Leu Thr Thr Val Val Ala Thr Gln 115 120 125 Ala Leu Arg Ala Ser Gly Val Ser Glu Lys Ala Gly Arg Lys Val Ile 130 135 140 Asp Gln Ala Ala Ala Val Glu Ile Leu Gln Thr Trp Leu Asp Ala Arg 145 150 155 160 Thr Arg Ala Leu Glu Pro Gln Ser Thr Asp Thr Gln Asp Phe Asp Glu 165 170 175 Lys Gly Asn Phe Pro Gly 180 <210> 513 <211> 903 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(880) <223> RXC02295 <400> 513 ttcccatgct aatccgcgaa aatggcactt caacagccat atactttaaa caacacaaat 60 gatgcaagac tgataccggg atgtgatagg agcgcaccac atg ggg ttg gaa tta 115 Met Gly Leu Glu Leu 1 5 gca gct agc ggg tgg ggc atc ctc atc gca ggc gcc gcc gta gcc gga 163 Ala Ala Ser Gly Trp Gly Ile Leu Ile Ala Gly Ala Ala Val Ala Gly 10 15 20 tgg atc gac gca gta atc ggc ggt ggc gga ctc gtc ctc atc ccg ctg 211 Trp Ile Asp Ala Val Ile Gly Gly Gly Gly Leu Val Leu Ile Pro Leu 25 30 35 atc ctc gcg gtc atg ccg caa ctc gca cct gtg aca gcg ctg gcc tcc 259 Ile Leu Ala Val Met Pro Gln Leu Ala Pro Val Thr Ala Leu Ala Ser 40 45 50 aac aaa ctg gca gcc gtc acc ggc acg gca tcg gcg gca ttc acc ctg 307 Asn Lys Leu Ala Ala Val Thr Gly Thr Ala Ser Ala Ala Phe Thr Leu 55 60 65 gtc agg cgc gtc aaa ccc gac aaa aaa ctg ctt gcg ctc tac gtt ctg 355 Val Arg Arg Val Lys Pro Asp Lys Lys Leu Leu Ala Leu Tyr Val Leu 70 75 80 85 gtg gca gct gtg tgc tcc ggt gca ggc gcc ctg gct gcg agt ctc att 403 Val Ala Ala Val Cys Ser Gly Ala Gly Ala Leu Ala Ala Ser Leu Ile 90 95 100 gac aaa caa atc atg cga ccg ctg atc atc gtg ttg atg ctg gtc gtt 451 Asp Lys Gln Ile Met Arg Pro Leu Ile Ile Val Leu Met Leu Val Val 105 110 115 ggc ctg atc gtg gtg ttc aaa cca aac ttc gga acc ggc gaa agc aaa 499 Gly Leu Ile Val Val Phe Lys Pro Asn Phe Gly Thr Gly Glu Ser Lys 120 125 130 gcc ctg ccc acc gga tgg aaa cgc tgg gcc gcc atc gtt gca gtc gga 547 Ala Leu Pro Thr Gly Trp Lys Arg Trp Ala Ala Ile Val Ala Val Gly 135 140 145 ctc atc gca gcc tac gac ggc atc ttc gga ccc gga acc ggc atg ttc 595 Leu Ile Ala Ala Tyr Asp Gly Ile Phe Gly Pro Gly Thr Gly Met Phe 150 155 160 165 ctc atc atg gcg ttc acc gca ctg ctc tcc caa aat ttc ctg tcc tcc 643 Leu Ile Met Ala Phe Thr Ala Leu Leu Ser Gln Asn Phe Leu Ser Ser 170 175 180 gca gcc atg gcg aag gtc gta aac acc gca aca aac ctg ggt gcg cta 691 Ala Ala Met Ala Lys Val Val Asn Thr Ala Thr Asn Leu Gly Ala Leu 185 190 195 att gta ttc atc atc ggc ggc cac atg tgg tgg acc cta gga ctc gtg 739 Ile Val Phe Ile Ile Gly Gly His Met Trp Trp Thr Leu Gly Leu Val 200 205 210 ctg gca gtc gcc aat gtc gca ggc gca caa ctc ggt gcc cga acg gtg 787 Leu Ala Val Ala Asn Val Ala Gly Ala Gln Leu Gly Ala Arg Thr Val 215 220 225 ctt ggt ggc ggt acc agg cta att aga tac gca cta cta acc ctg gtt 835 Leu Gly Gly Gly Thr Arg Leu Ile Arg Tyr Ala Leu Leu Thr Leu Val 230 235 240 245 gtc gtc atg agc gtc tac ctc acc tgg caa caa atc caa gga atg 880 Val Val Met Ser Val Tyr Leu Thr Trp Gln Gln Ile Gln Gly Met 250 255 260 tagataagtc ggggcaaact cta 903 <210> 514 <211> 260 <212> PRT <213> Corynebacterium glutamicum <400> 514 Met Gly Leu Glu Leu Ala Ala Ser Gly Trp Gly Ile Leu Ile Ala Gly 1 5 10 15 Ala Ala Val Ala Gly Trp Ile Asp Ala Val Ile Gly Gly Gly Gly Leu 20 25 30 Val Leu Ile Pro Leu Ile Leu Ala Val Met Pro Gln Leu Ala Pro Val 35 40 45 Thr Ala Leu Ala Ser Asn Lys Leu Ala Ala Val Thr Gly Thr Ala Ser 50 55 60 Ala Ala Phe Thr Leu Val Arg Arg Val Lys Pro Asp Lys Lys Leu Leu 65 70 75 80 Ala Leu Tyr Val Leu Val Ala Ala Val Cys Ser Gly Ala Gly Ala Leu 85 90 95 Ala Ala Ser Leu Ile Asp Lys Gln Ile Met Arg Pro Leu Ile Ile Val 100 105 110 Leu Met Leu Val Val Gly Leu Ile Val Val Phe Lys Pro Asn Phe Gly 115 120 125 Thr Gly Glu Ser Lys Ala Leu Pro Thr Gly Trp Lys Arg Trp Ala Ala 130 135 140 Ile Val Ala Val Gly Leu Ile Ala Ala Tyr Asp Gly Ile Phe Gly Pro 145 150 155 160 Gly Thr Gly Met Phe Leu Ile Met Ala Phe Thr Ala Leu Leu Ser Gln 165 170 175 Asn Phe Leu Ser Ser Ala Ala Met Ala Lys Val Val Asn Thr Ala Thr 180 185 190 Asn Leu Gly Ala Leu Ile Val Phe Ile Ile Gly Gly His Met Trp Trp 195 200 205 Thr Leu Gly Leu Val Leu Ala Val Ala Asn Val Ala Gly Ala Gln Leu 210 215 220 Gly Ala Arg Thr Val Leu Gly Gly Gly Thr Arg Leu Ile Arg Tyr Ala 225 230 235 240 Leu Leu Thr Leu Val Val Val Met Ser Val Tyr Leu Thr Trp Gln Gln 245 250 255 Ile Gln Gly Met 260 <210> 515 <211> 1132 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1132) <223> RXN03063 <400> 515 tgtctacaac ttcgccctca tggacatatt aacttcgttg cctcggagag aatactcatc 60 acctagacaa cagtttgtat ctcacctcac aggaggaacc gtg gaa gat ctc tca 115 Val Glu Asp Leu Ser 1 5 tac cgc atc ccg cag tcg cgc acc gtg gcc gag cag gtg cca ggg ccg 163 Tyr Arg Ile Pro Gln Ser Arg Thr Val Ala Glu Gln Val Pro Gly Pro 10 15 20 aag tcg aaa gcg ctg gat gag cgt cga caa gca gca gta gca cga gca 211 Lys Ser Lys Ala Leu Asp Glu Arg Arg Gln Ala Ala Val Ala Arg Ala 25 30 35 ctt gca ccg ggt ctg cct gga tac gtg gtg gac gca gac ggt ggc atc 259 Leu Ala Pro Gly Leu Pro Gly Tyr Val Val Asp Ala Asp Gly Gly Ile 40 45 50 ttg gct gac gcg gac ggc aac cgt ttc atc gac ctg gcc tcc ggc atc 307 Leu Ala Asp Ala Asp Gly Asn Arg Phe Ile Asp Leu Ala Ser Gly Ile 55 60 65 gcc gtg acc acg gtc ggc gga tcc aac gcg gcc gtc gcg aaa gcc gtc 355 Ala Val Thr Thr Val Gly Gly Ser Asn Ala Ala Val Ala Lys Ala Val 70 75 80 85 ggc gcc gca gct gcc cgc ttc acc cac acc tgc ttc atg gtc tca cct 403 Gly Ala Ala Ala Ala Arg Phe Thr His Thr Cys Phe Met Val Ser Pro 90 95 100 tat gaa act tac gtg gcc atg gcg gag aga ctc aac gcc ttg act cca 451 Tyr Glu Thr Tyr Val Ala Met Ala Glu Arg Leu Asn Ala Leu Thr Pro 105 110 115 ggc gat cac gac aag aag agc gcg ctg ttt aac tct ggc gcc gaa gcc 499 Gly Asp His Asp Lys Lys Ser Ala Leu Phe Asn Ser Gly Ala Glu Ala 120 125 130 gtg gaa aac gcc gtc aag gtg gca cgc gcc tac acc ggc aag ggc gcg 547 Val Glu Asn Ala Val Lys Val Ala Arg Ala Tyr Thr Gly Lys Gly Ala 135 140 145 gtc gtg gtg ttc gac aac gcg tac cac gga cgg acc aac ctc acc atg 595 Val Val Val Phe Asp Asn Ala Tyr His Gly Arg Thr Asn Leu Thr Met 150 155 160 165 gcg atg acc gcg aag aac cgc cca tac aag tcc gga ttc gga cca cta 643 Ala Met Thr Ala Lys Asn Arg Pro Tyr Lys Ser Gly Phe Gly Pro Leu 170 175 180 gcc gca gac gtc tac cgt gca cca atg tct tac cca ctg cgc gac gga 691 Ala Ala Asp Val Tyr Arg Ala Pro Met Ser Tyr Pro Leu Arg Asp Gly 185 190 195 ctg tcc ggc ccg gaa gcc gca gag cgc gcg atc tcc gtg atc gaa tcc 739 Leu Ser Gly Pro Glu Ala Ala Glu Arg Ala Ile Ser Val Ile Glu Ser 200 205 210 cag gtc gga gcc gaa aac ctc gcc tgc gtg gtc att gaa ccg atc cag 787 Gln Val Gly Ala Glu Asn Leu Ala Cys Val Val Ile Glu Pro Ile Gln 215 220 225 ggc gaa ggc gga ttc atc gtc ccc gca cca gga ttc ctc gca gcc att 835 Gly Glu Gly Gly Phe Ile Val Pro Ala Pro Gly Phe Leu Ala Ala Ile 230 235 240 245 tcc acc tgg tgc cgc gag aac gac gtg gtg ttc atc gcc gat gaa atc 883 Ser Thr Trp Cys Arg Glu Asn Asp Val Val Phe Ile Ala Asp Glu Ile 250 255 260 caa tct ggc ttc ctg cgc acc ggc gac tgg ttc gcc agc gac gca gaa 931 Gln Ser Gly Phe Leu Arg Thr Gly Asp Trp Phe Ala Ser Asp Ala Glu 265 270 275 ggt gtg atc ccc gac gtc atc acc acc gca aaa ggc atc gcc ggc ggc 979 Gly Val Ile Pro Asp Val Ile Thr Thr Ala Lys Gly Ile Ala Gly Gly 280 285 290 atg cca cta tcc gca gtg acc ggc cgc gca gaa atc atg gac gca ccc 1027 Met Pro Leu Ser Ala Val Thr Gly Arg Ala Glu Ile Met Asp Ala Pro 295 300 305 ggc ccc ggc gcg ctc ggc gga acc tac ggc gga aac ccc gtt gct tgc 1075 Gly Pro Gly Ala Leu Gly Gly Thr Tyr Gly Gly Asn Pro Val Ala Cys 310 315 320 325 gcc gcg gca ctt gca gcc att gaa gtg atg gaa caa gcc gac ctt aag 1123 Ala Ala Ala Leu Ala Ala Ile Glu Val Met Glu Gln Ala Asp Leu Lys 330 335 340 acc cgc gcg 1132 Thr Arg Ala <210> 516 <211> 344 <212> PRT <213> Corynebacterium glutamicum <400> 516 Val Glu Asp Leu Ser Tyr Arg Ile Pro Gln Ser Arg Thr Val Ala Glu 1 5 10 15 Gln Val Pro Gly Pro Lys Ser Lys Ala Leu Asp Glu Arg Arg Gln Ala 20 25 30 Ala Val Ala Arg Ala Leu Ala Pro Gly Leu Pro Gly Tyr Val Val Asp 35 40 45 Ala Asp Gly Gly Ile Leu Ala Asp Ala Asp Gly Asn Arg Phe Ile Asp 50 55 60 Leu Ala Ser Gly Ile Ala Val Thr Thr Val Gly Gly Ser Asn Ala Ala 65 70 75 80 Val Ala Lys Ala Val Gly Ala Ala Ala Ala Arg Phe Thr His Thr Cys 85 90 95 Phe Met Val Ser Pro Tyr Glu Thr Tyr Val Ala Met Ala Glu Arg Leu 100 105 110 Asn Ala Leu Thr Pro Gly Asp His Asp Lys Lys Ser Ala Leu Phe Asn 115 120 125 Ser Gly Ala Glu Ala Val Glu Asn Ala Val Lys Val Ala Arg Ala Tyr 130 135 140 Thr Gly Lys Gly Ala Val Val Val Phe Asp Asn Ala Tyr His Gly Arg 145 150 155 160 Thr Asn Leu Thr Met Ala Met Thr Ala Lys Asn Arg Pro Tyr Lys Ser 165 170 175 Gly Phe Gly Pro Leu Ala Ala Asp Val Tyr Arg Ala Pro Met Ser Tyr 180 185 190 Pro Leu Arg Asp Gly Leu Ser Gly Pro Glu Ala Ala Glu Arg Ala Ile 195 200 205 Ser Val Ile Glu Ser Gln Val Gly Ala Glu Asn Leu Ala Cys Val Val 210 215 220 Ile Glu Pro Ile Gln Gly Glu Gly Gly Phe Ile Val Pro Ala Pro Gly 225 230 235 240 Phe Leu Ala Ala Ile Ser Thr Trp Cys Arg Glu Asn Asp Val Val Phe 245 250 255 Ile Ala Asp Glu Ile Gln Ser Gly Phe Leu Arg Thr Gly Asp Trp Phe 260 265 270 Ala Ser Asp Ala Glu Gly Val Ile Pro Asp Val Ile Thr Thr Ala Lys 275 280 285 Gly Ile Ala Gly Gly Met Pro Leu Ser Ala Val Thr Gly Arg Ala Glu 290 295 300 Ile Met Asp Ala Pro Gly Pro Gly Ala Leu Gly Gly Thr Tyr Gly Gly 305 310 315 320 Asn Pro Val Ala Cys Ala Ala Ala Leu Ala Ala Ile Glu Val Met Glu 325 330 335 Gln Ala Asp Leu Lys Thr Arg Ala 340 <210> 517 <211> 1491 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1468) <223> RXN02970 <400> 517 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc gtg tgg ccg atg atc tcc ggc aac cga ttc cac 1363 Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser Gly Asn Arg Phe His 410 415 420 atc gcg ccg ccg ctg acc acc act gat gac gaa ttg gta gca ctg ctg 1411 Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu Leu Val Ala Leu Leu 425 430 435 gac gcg gtg gaa gct gca gcc caa gct gtc gag ctg acc ttc gct ggg 1459 Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu Leu Thr Phe Ala Gly 440 445 450 gcg ttg ttc taagttttct agataacaag gcc 1491 Ala Leu Phe 455 <210> 518 <211> 456 <212> PRT <213> Corynebacterium glutamicum <400> 518 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly Val Trp Pro Met Ile Ser 405 410 415 Gly Asn Arg Phe His Ile Ala Pro Pro Leu Thr Thr Thr Asp Asp Glu 420 425 430 Leu Val Ala Leu Leu Asp Ala Val Glu Ala Ala Ala Gln Ala Val Glu 435 440 445 Leu Thr Phe Ala Gly Ala Leu Phe 450 455 <210> 519 <211> 1330 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1330) <223> FRXA01009 <400> 519 aaccgacaaa acagccgttc acgtgctaaa gcagctcggc ttgatctagg gtgaggtgag 60 ttatttaaag acttcataat attttgggga gtgaactggt ttg gca ttg aag ggt 115 Leu Ala Leu Lys Gly 1 5 tac acc aac ttt gac ggt gaa ttc atc gaa ttc gga tct gtg caa gca 163 Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe Gly Ser Val Gln Ala 10 15 20 aaa gaa gag gaa aaa cgg gca ttc gac aac gat cgc gcg cac gtt ttc 211 Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp Arg Ala His Val Phe 25 30 35 cac tcc tgg tcc gcg cag gac aaa atc agc ccc aaa gta tgg gca gct 259 His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro Lys Val Trp Ala Ala 40 45 50 gcc gaa ggt tcc acg ctg tac gac ttc gac ggc aac gcc ttc atc gac 307 Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly Asn Ala Phe Ile Asp 55 60 65 atg ggt tcc caa ctt gtc tcg gca aac tta ggc cac aac aac cct cga 355 Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly His Asn Asn Pro Arg 70 75 80 85 tta gtt gag gcg atc cag cgc caa gca gcc cgg ttg acc aac atc aac 403 Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg Leu Thr Asn Ile Asn 90 95 100 ccg gcc ttc ggc aat gat gtg cgc tct gat gtt gct gca aag atc gtg 451 Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val Ala Ala Lys Ile Val 105 110 115 tcg atg gcc cgt ggc gaa ttc tcc cac gtg ttt ttc acc aac ggc ggc 499 Ser Met Ala Arg Gly Glu Phe Ser His Val Phe Phe Thr Asn Gly Gly 120 125 130 gcc gac gcc atc gag cac tcc atc cgc atg gct cgc ctg cac acc gga 547 Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala Arg Leu His Thr Gly 135 140 145 cgc aac aaa att ctg tcc gca tac cgc agc tac cac ggc gca acc gga 595 Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr His Gly Ala Thr Gly 150 155 160 165 tcc gcg atg atg ctc acc ggc gaa cac cgc cgc ctg ggc aac ccc acc 643 Ser Ala Met Met Leu Thr Gly Glu His Arg Arg Leu Gly Asn Pro Thr 170 175 180 acc gac cca gat atc tac cac ttc tgg gca cca ttc ctg cac cac tcc 691 Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro Phe Leu His His Ser 185 190 195 tca ttc ttt gcc acc acc caa gaa gaa gaa tgc gaa cgc gca ctc aag 739 Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys Glu Arg Ala Leu Lys 200 205 210 cac ttg gaa gat gtc atc gcg ttt gaa ggt gct ggc atg atc gca gcg 787 His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala Gly Met Ile Ala Ala 215 220 225 atc gtc ctg gag cca gtg gtg gga tca tca gga atc atc ctg cca cca 835 Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly Ile Ile Leu Pro Pro 230 235 240 245 gca ggt tac tta aat ggc gtg cgc gaa ctt tgc aac aag cac ggc atc 883 Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys Asn Lys His Gly Ile 250 255 260 ctc ttc atc gcc gac gaa gtc atg gtc gga ttc gga cgc acc gga aaa 931 Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe Gly Arg Thr Gly Lys 265 270 275 ctg ttt gct tac gag cat gct ggc gac gat ttc cag cca gac atg atc 979 Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe Gln Pro Asp Met Ile 280 285 290 acc ttc gcc aag ggt gtt aac gca ggt tac gcc cca ctc ggt ggc atc 1027 Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala Pro Leu Gly Gly Ile 295 300 305 gtg atg acc caa tca atc cgc gat acc ttc gga tca gag gca tac tcc 1075 Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly Ser Glu Ala Tyr Ser 310 315 320 325 ggc gga ctc acc tac tcc gga cac cca ctt gca gta gca ccc gcc aag 1123 Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala Val Ala Pro Ala Lys 330 335 340 gca gcg ctg gag att tac gcg gaa gga gag atc att cca cgc gta gct 1171 Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile Ile Pro Arg Val Ala 345 350 355 cga ctt ggc gct gaa ctg atc gaa cct cgc ctt cgt gaa cta gcg gaa 1219 Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu Arg Glu Leu Ala Glu 360 365 370 gaa aac gta gcg atc gct gac gtg cgg ggc atc gga ttc ttc tgg gca 1267 Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile Gly Phe Phe Trp Ala 375 380 385 gtg gag ttc aat gca gac gcc act gcc atg gct gcc ggt gct gca gaa 1315 Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala Ala Gly Ala Ala Glu 390 395 400 405 ttc aag gaa cgc ggc 1330 Phe Lys Glu Arg Gly 410 <210> 520 <211> 410 <212> PRT <213> Corynebacterium glutamicum <400> 520 Leu Ala Leu Lys Gly Tyr Thr Asn Phe Asp Gly Glu Phe Ile Glu Phe 1 5 10 15 Gly Ser Val Gln Ala Lys Glu Glu Glu Lys Arg Ala Phe Asp Asn Asp 20 25 30 Arg Ala His Val Phe His Ser Trp Ser Ala Gln Asp Lys Ile Ser Pro 35 40 45 Lys Val Trp Ala Ala Ala Glu Gly Ser Thr Leu Tyr Asp Phe Asp Gly 50 55 60 Asn Ala Phe Ile Asp Met Gly Ser Gln Leu Val Ser Ala Asn Leu Gly 65 70 75 80 His Asn Asn Pro Arg Leu Val Glu Ala Ile Gln Arg Gln Ala Ala Arg 85 90 95 Leu Thr Asn Ile Asn Pro Ala Phe Gly Asn Asp Val Arg Ser Asp Val 100 105 110 Ala Ala Lys Ile Val Ser Met Ala Arg Gly Glu Phe Ser His Val Phe 115 120 125 Phe Thr Asn Gly Gly Ala Asp Ala Ile Glu His Ser Ile Arg Met Ala 130 135 140 Arg Leu His Thr Gly Arg Asn Lys Ile Leu Ser Ala Tyr Arg Ser Tyr 145 150 155 160 His Gly Ala Thr Gly Ser Ala Met Met Leu Thr Gly Glu His Arg Arg 165 170 175 Leu Gly Asn Pro Thr Thr Asp Pro Asp Ile Tyr His Phe Trp Ala Pro 180 185 190 Phe Leu His His Ser Ser Phe Phe Ala Thr Thr Gln Glu Glu Glu Cys 195 200 205 Glu Arg Ala Leu Lys His Leu Glu Asp Val Ile Ala Phe Glu Gly Ala 210 215 220 Gly Met Ile Ala Ala Ile Val Leu Glu Pro Val Val Gly Ser Ser Gly 225 230 235 240 Ile Ile Leu Pro Pro Ala Gly Tyr Leu Asn Gly Val Arg Glu Leu Cys 245 250 255 Asn Lys His Gly Ile Leu Phe Ile Ala Asp Glu Val Met Val Gly Phe 260 265 270 Gly Arg Thr Gly Lys Leu Phe Ala Tyr Glu His Ala Gly Asp Asp Phe 275 280 285 Gln Pro Asp Met Ile Thr Phe Ala Lys Gly Val Asn Ala Gly Tyr Ala 290 295 300 Pro Leu Gly Gly Ile Val Met Thr Gln Ser Ile Arg Asp Thr Phe Gly 305 310 315 320 Ser Glu Ala Tyr Ser Gly Gly Leu Thr Tyr Ser Gly His Pro Leu Ala 325 330 335 Val Ala Pro Ala Lys Ala Ala Leu Glu Ile Tyr Ala Glu Gly Glu Ile 340 345 350 Ile Pro Arg Val Ala Arg Leu Gly Ala Glu Leu Ile Glu Pro Arg Leu 355 360 365 Arg Glu Leu Ala Glu Glu Asn Val Ala Ile Ala Asp Val Arg Gly Ile 370 375 380 Gly Phe Phe Trp Ala Val Glu Phe Asn Ala Asp Ala Thr Ala Met Ala 385 390 395 400 Ala Gly Ala Ala Glu Phe Lys Glu Arg Gly 405 410 <210> 521 <211> 1998 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1975) <223> RXA01551 <400> 521 cactacgtag gcgtacccca ccatcaccgc gtcgaaaagc gccctctctt aacccccgca 60 agggggtaac ttttacgcgc acgcgtgcaa cgcgctagtt ttg aag gca gtc ccc 115 Leu Lys Ala Val Pro 1 5 acg ggc gcc cga gca cgg gct gag atc gcg ctg att gct gcg cga gca 163 Thr Gly Ala Arg Ala Arg Ala Glu Ile Ala Leu Ile Ala Ala Arg Ala 10 15 20 ccg ttt gaa cct gtc cgg tta gca ccg gcg aag gaa gag agg aat ggt 211 Pro Phe Glu Pro Val Arg Leu Ala Pro Ala Lys Glu Glu Arg Asn Gly 25 30 35 gca atg acg cct acc caa aat gag atc cac ccg aaa cat agc tac tcc 259 Ala Met Thr Pro Thr Gln Asn Glu Ile His Pro Lys His Ser Tyr Ser 40 45 50 ccc atc cgc aag gac ggt ctc gag gtc ccg gag acc gaa atc cgc ctc 307 Pro Ile Arg Lys Asp Gly Leu Glu Val Pro Glu Thr Glu Ile Arg Leu 55 60 65 gat gac tcg cca agc ggc ccc aac gaa ccc ttc cgc atc tac cgc acc 355 Asp Asp Ser Pro Ser Gly Pro Asn Glu Pro Phe Arg Ile Tyr Arg Thr 70 75 80 85 cgt ggc cca gaa acc aac ccc aag cag gga ctt ccg cgg ctg cgc gag 403 Arg Gly Pro Glu Thr Asn Pro Lys Gln Gly Leu Pro Arg Leu Arg Glu 90 95 100 tca tgg atc acc gcc cgc ggc gac gtt gcc acc tat cag ggg cgc gag 451 Ser Trp Ile Thr Ala Arg Gly Asp Val Ala Thr Tyr Gln Gly Arg Glu 105 110 115 cgt ttg ctt atc gac gac ggc cgc tcg gca atg cgt cga ggt caa gct 499 Arg Leu Leu Ile Asp Asp Gly Arg Ser Ala Met Arg Arg Gly Gln Ala 120 125 130 tcg gct gag tgg aaa ggc caa aaa cca gct cct ttg aag gcg cta cct 547 Ser Ala Glu Trp Lys Gly Gln Lys Pro Ala Pro Leu Lys Ala Leu Pro 135 140 145 ggc aaa aga gtc acc caa atg gcc tat gca cgt gct ggc gtg att act 595 Gly Lys Arg Val Thr Gln Met Ala Tyr Ala Arg Ala Gly Val Ile Thr 150 155 160 165 cgt gaa atg gag ttt gta gcg ctg cgc gaa cac gtt gat gcg gag ttt 643 Arg Glu Met Glu Phe Val Ala Leu Arg Glu His Val Asp Ala Glu Phe 170 175 180 gtg cgc tct gag gtg gcg cgc ggt cgg gcc att att ccc aac aac gtc 691 Val Arg Ser Glu Val Ala Arg Gly Arg Ala Ile Ile Pro Asn Asn Val 185 190 195 aac cac ccc gaa tct gaa ccg atg att att ggt cgc aaa ttt ttg acc 739 Asn His Pro Glu Ser Glu Pro Met Ile Ile Gly Arg Lys Phe Leu Thr 200 205 210 aaa atc aac gcc aat att ggc aat tct gcg gtc acc tct tca atc gag 787 Lys Ile Asn Ala Asn Ile Gly Asn Ser Ala Val Thr Ser Ser Ile Glu 215 220 225 gaa gag gtg tcc aag ctg cag tgg gcc acg cgc tgg ggt gcc gat acc 835 Glu Glu Val Ser Lys Leu Gln Trp Ala Thr Arg Trp Gly Ala Asp Thr 230 235 240 245 gtg atg gat cta tcc acc ggc gat gat att cac acc acc cgc gaa tgg 883 Val Met Asp Leu Ser Thr Gly Asp Asp Ile His Thr Thr Arg Glu Trp 250 255 260 att atc cgc aac tcc ccc gtt cct atc ggc acc gtc ccg atc tac caa 931 Ile Ile Arg Asn Ser Pro Val Pro Ile Gly Thr Val Pro Ile Tyr Gln 265 270 275 gcg ctg gaa aaa gta aat ggc gtg gcc gca gac ctt aac tgg gaa gta 979 Ala Leu Glu Lys Val Asn Gly Val Ala Ala Asp Leu Asn Trp Glu Val 280 285 290 ttc cgc gat acc atc att gag cag tgt gaa caa ggc gtg gac tat atg 1027 Phe Arg Asp Thr Ile Ile Glu Gln Cys Glu Gln Gly Val Asp Tyr Met 295 300 305 acc atc cac gcc ggc gtc ctg ctg gct tat atc cca ctg act acc cgt 1075 Thr Ile His Ala Gly Val Leu Leu Ala Tyr Ile Pro Leu Thr Thr Arg 310 315 320 325 cgt gtc acc ggc att gtc tcc cgc ggc gga tcc att atg gcc ggt tgg 1123 Arg Val Thr Gly Ile Val Ser Arg Gly Gly Ser Ile Met Ala Gly Trp 330 335 340 tgt ctg gcg cat cac cgc gaa tca ttc ctc tac gag cat ttc gac gag 1171 Cys Leu Ala His His Arg Glu Ser Phe Leu Tyr Glu His Phe Asp Glu 345 350 355 ctg tgc gaa atc ttt gca caa tat gac gtc gca ttc tcc ctc ggt gat 1219 Leu Cys Glu Ile Phe Ala Gln Tyr Asp Val Ala Phe Ser Leu Gly Asp 360 365 370 ggc cta cgc ccc gga tcg ctt gcc gat gcc aac gac gcc gcg caa ttc 1267 Gly Leu Arg Pro Gly Ser Leu Ala Asp Ala Asn Asp Ala Ala Gln Phe 375 380 385 gcc gag ctg aaa acc att ggt gag ctc acc caa cgc gcc tgg gaa tac 1315 Ala Glu Leu Lys Thr Ile Gly Glu Leu Thr Gln Arg Ala Trp Glu Tyr 390 395 400 405 gat gta caa gta atg gtc gaa gga cct gga cac gtg cca cta aac atg 1363 Asp Val Gln Val Met Val Glu Gly Pro Gly His Val Pro Leu Asn Met 410 415 420 atc cag gaa aac aac gag ctg gaa caa aag tgg gca gcg gac gca cct 1411 Ile Gln Glu Asn Asn Glu Leu Glu Gln Lys Trp Ala Ala Asp Ala Pro 425 430 435 ttt tac act ctt gga cca cta gtt acc gac atc gct cca ggt tat gac 1459 Phe Tyr Thr Leu Gly Pro Leu Val Thr Asp Ile Ala Pro Gly Tyr Asp 440 445 450 cac atc act tct gcc att ggt gca gct cac atc gcc atg ggt ggc acc 1507 His Ile Thr Ser Ala Ile Gly Ala Ala His Ile Ala Met Gly Gly Thr 455 460 465 gcc atg ctg tgt tat gtc acc ccg aaa gaa cac ctt ggc ctg ccc aac 1555 Ala Met Leu Cys Tyr Val Thr Pro Lys Glu His Leu Gly Leu Pro Asn 470 475 480 485 cgt gac gac gtc aaa acc ggc gta atc acc tac aag ctc gct gcc cac 1603 Arg Asp Asp Val Lys Thr Gly Val Ile Thr Tyr Lys Leu Ala Ala His 490 495 500 gca gca gat gtg gcc aag ggt cat ccc ggc gcg cgt gcc tgg gac gac 1651 Ala Ala Asp Val Ala Lys Gly His Pro Gly Ala Arg Ala Trp Asp Asp 505 510 515 gcc atg agt aaa gcg cgt ttt gaa ttc cgt tgg aat gat cag ttt gcg 1699 Ala Met Ser Lys Ala Arg Phe Glu Phe Arg Trp Asn Asp Gln Phe Ala 520 525 530 ctc tcc ctc gac ccc gac act gca atc gct tat cac gac gaa acc ctg 1747 Leu Ser Leu Asp Pro Asp Thr Ala Ile Ala Tyr His Asp Glu Thr Leu 535 540 545 ccg gca gag cct gcg aaa acc gca cac ttc tgt tca atg tgt ggc ccg 1795 Pro Ala Glu Pro Ala Lys Thr Ala His Phe Cys Ser Met Cys Gly Pro 550 555 560 565 aag ttc tgc tcc atg cga att agc cag gac att cgc gat atg ttt ggc 1843 Lys Phe Cys Ser Met Arg Ile Ser Gln Asp Ile Arg Asp Met Phe Gly 570 575 580 gat caa atc gcg gaa ttg ggg atg cct ggg gtt ggg gat tct tct agt 1891 Asp Gln Ile Ala Glu Leu Gly Met Pro Gly Val Gly Asp Ser Ser Ser 585 590 595 gct gtt gct tct agt ggg gca cgg gag ggg atg gct gag aaa tcc cgg 1939 Ala Val Ala Ser Ser Gly Ala Arg Glu Gly Met Ala Glu Lys Ser Arg 600 605 610 gaa ttt att gct ggt ggt gcg gag gtt tat cgg cgt tagacagagc 1985 Glu Phe Ile Ala Gly Gly Ala Glu Val Tyr Arg Arg 615 620 625 gatcccagat agc 1998 <210> 522 <211> 625 <212> PRT <213> Corynebacterium glutamicum <400> 522 Leu Lys Ala Val Pro Thr Gly Ala Arg Ala Arg Ala Glu Ile Ala Leu 1 5 10 15 Ile Ala Ala Arg Ala Pro Phe Glu Pro Val Arg Leu Ala Pro Ala Lys 20 25 30 Glu Glu Arg Asn Gly Ala Met Thr Pro Thr Gln Asn Glu Ile His Pro 35 40 45 Lys His Ser Tyr Ser Pro Ile Arg Lys Asp Gly Leu Glu Val Pro Glu 50 55 60 Thr Glu Ile Arg Leu Asp Asp Ser Pro Ser Gly Pro Asn Glu Pro Phe 65 70 75 80 Arg Ile Tyr Arg Thr Arg Gly Pro Glu Thr Asn Pro Lys Gln Gly Leu 85 90 95 Pro Arg Leu Arg Glu Ser Trp Ile Thr Ala Arg Gly Asp Val Ala Thr 100 105 110 Tyr Gln Gly Arg Glu Arg Leu Leu Ile Asp Asp Gly Arg Ser Ala Met 115 120 125 Arg Arg Gly Gln Ala Ser Ala Glu Trp Lys Gly Gln Lys Pro Ala Pro 130 135 140 Leu Lys Ala Leu Pro Gly Lys Arg Val Thr Gln Met Ala Tyr Ala Arg 145 150 155 160 Ala Gly Val Ile Thr Arg Glu Met Glu Phe Val Ala Leu Arg Glu His 165 170 175 Val Asp Ala Glu Phe Val Arg Ser Glu Val Ala Arg Gly Arg Ala Ile 180 185 190 Ile Pro Asn Asn Val Asn His Pro Glu Ser Glu Pro Met Ile Ile Gly 195 200 205 Arg Lys Phe Leu Thr Lys Ile Asn Ala Asn Ile Gly Asn Ser Ala Val 210 215 220 Thr Ser Ser Ile Glu Glu Glu Val Ser Lys Leu Gln Trp Ala Thr Arg 225 230 235 240 Trp Gly Ala Asp Thr Val Met Asp Leu Ser Thr Gly Asp Asp Ile His 245 250 255 Thr Thr Arg Glu Trp Ile Ile Arg Asn Ser Pro Val Pro Ile Gly Thr 260 265 270 Val Pro Ile Tyr Gln Ala Leu Glu Lys Val Asn Gly Val Ala Ala Asp 275 280 285 Leu Asn Trp Glu Val Phe Arg Asp Thr Ile Ile Glu Gln Cys Glu Gln 290 295 300 Gly Val Asp Tyr Met Thr Ile His Ala Gly Val Leu Leu Ala Tyr Ile 305 310 315 320 Pro Leu Thr Thr Arg Arg Val Thr Gly Ile Val Ser Arg Gly Gly Ser 325 330 335 Ile Met Ala Gly Trp Cys Leu Ala His His Arg Glu Ser Phe Leu Tyr 340 345 350 Glu His Phe Asp Glu Leu Cys Glu Ile Phe Ala Gln Tyr Asp Val Ala 355 360 365 Phe Ser Leu Gly Asp Gly Leu Arg Pro Gly Ser Leu Ala Asp Ala Asn 370 375 380 Asp Ala Ala Gln Phe Ala Glu Leu Lys Thr Ile Gly Glu Leu Thr Gln 385 390 395 400 Arg Ala Trp Glu Tyr Asp Val Gln Val Met Val Glu Gly Pro Gly His 405 410 415 Val Pro Leu Asn Met Ile Gln Glu Asn Asn Glu Leu Glu Gln Lys Trp 420 425 430 Ala Ala Asp Ala Pro Phe Tyr Thr Leu Gly Pro Leu Val Thr Asp Ile 435 440 445 Ala Pro Gly Tyr Asp His Ile Thr Ser Ala Ile Gly Ala Ala His Ile 450 455 460 Ala Met Gly Gly Thr Ala Met Leu Cys Tyr Val Thr Pro Lys Glu His 465 470 475 480 Leu Gly Leu Pro Asn Arg Asp Asp Val Lys Thr Gly Val Ile Thr Tyr 485 490 495 Lys Leu Ala Ala His Ala Ala Asp Val Ala Lys Gly His Pro Gly Ala 500 505 510 Arg Ala Trp Asp Asp Ala Met Ser Lys Ala Arg Phe Glu Phe Arg Trp 515 520 525 Asn Asp Gln Phe Ala Leu Ser Leu Asp Pro Asp Thr Ala Ile Ala Tyr 530 535 540 His Asp Glu Thr Leu Pro Ala Glu Pro Ala Lys Thr Ala His Phe Cys 545 550 555 560 Ser Met Cys Gly Pro Lys Phe Cys Ser Met Arg Ile Ser Gln Asp Ile 565 570 575 Arg Asp Met Phe Gly Asp Gln Ile Ala Glu Leu Gly Met Pro Gly Val 580 585 590 Gly Asp Ser Ser Ser Ala Val Ala Ser Ser Gly Ala Arg Glu Gly Met 595 600 605 Ala Glu Lys Ser Arg Glu Phe Ile Ala Gly Gly Ala Glu Val Tyr Arg 610 615 620 Arg 625 <210> 523 <211> 1013 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(990) <223> RXA01019 <400> 523 act ttg gcg cac tca ctt tca ttc ccg gat tcg ctt cgc gac ggg cca 48 Thr Leu Ala His Ser Leu Ser Phe Pro Asp Ser Leu Arg Asp Gly Pro 1 5 10 15 acc gtt gga gac ctc ggg gaa ttt gaa gtg att cgg gta atc acg gag 96 Thr Val Gly Asp Leu Gly Glu Phe Glu Val Ile Arg Val Ile Thr Glu 20 25 30 caa gct gga tca tct ctc aac ggc gat gac gca gct gtg ctt cgg cat 144 Gln Ala Gly Ser Ser Leu Asn Gly Asp Asp Ala Ala Val Leu Arg His 35 40 45 gca tca ccc aat tcc agg gct gtt gtc acc acc gac atg ttg gtt gcg 192 Ala Ser Pro Asn Ser Arg Ala Val Val Thr Thr Asp Met Leu Val Ala 50 55 60 ggt agg cat ttc caa ttg gat tgg tcc acc ccg gaa caa ata ggg cag 240 Gly Arg His Phe Gln Leu Asp Trp Ser Thr Pro Glu Gln Ile Gly Gln 65 70 75 80 aag gcg att gtg cag aac ttt gct gat att gag gcg atg ggt gca cgt 288 Lys Ala Ile Val Gln Asn Phe Ala Asp Ile Glu Ala Met Gly Ala Arg 85 90 95 cca gta gcc gca ttg ttg gcg att tcc gcc ccc aca cac acc ccc gtg 336 Pro Val Ala Ala Leu Leu Ala Ile Ser Ala Pro Thr His Thr Pro Val 100 105 110 gag ttt gtc cga ggc tta gcc cgt ggc atg aat caa cgc ttg gag gag 384 Glu Phe Val Arg Gly Leu Ala Arg Gly Met Asn Gln Arg Leu Glu Glu 115 120 125 tac tcc gcg gaa ctt gtt ggc gga gac atc acc agc ggg gac tcc ttg 432 Tyr Ser Ala Glu Leu Val Gly Gly Asp Ile Thr Ser Gly Asp Ser Leu 130 135 140 gtt att gct gta act gca att ggt caa ctg ggt gga tcc ttg cca gag 480 Val Ile Ala Val Thr Ala Ile Gly Gln Leu Gly Gly Ser Leu Pro Glu 145 150 155 160 ctg acg ttg gga cgt gcc cga cca gga cag acc ctg gtg gcc cac gga 528 Leu Thr Leu Gly Arg Ala Arg Pro Gly Gln Thr Leu Val Ala His Gly 165 170 175 aag atc ggt tac tcc gca gca ggc ctt gct cta ctg cag cac ttt ggt 576 Lys Ile Gly Tyr Ser Ala Ala Gly Leu Ala Leu Leu Gln His Phe Gly 180 185 190 cca gac aac gtt cca gag cac ctt cgc ccc ttg gtg gat gca cac tgc 624 Pro Asp Asn Val Pro Glu His Leu Arg Pro Leu Val Asp Ala His Cys 195 200 205 gca cca gtt ctc acc cca ggc cga ggc atg gtg gca cgc gct gct gga 672 Ala Pro Val Leu Thr Pro Gly Arg Gly Met Val Ala Arg Ala Ala Gly 210 215 220 gcg acc gcc atg act gat aac tcg gac gga ctg att gtg gat ctt aac 720 Ala Thr Ala Met Thr Asp Asn Ser Asp Gly Leu Ile Val Asp Leu Asn 225 230 235 240 caa atg gcc atg aag tct ggt gtg cgc atc gat gtg gat tcc tgt agc 768 Gln Met Ala Met Lys Ser Gly Val Arg Ile Asp Val Asp Ser Cys Ser 245 250 255 atc agc ccc gat gaa ctc ctt agc gaa gcc gct tcc gta ctc gga aca 816 Ile Ser Pro Asp Glu Leu Leu Ser Glu Ala Ala Ser Val Leu Gly Thr 260 265 270 gac gcc tgg cga tgg atc tta agc ggc ggg gaa gac cac acc ctg ctc 864 Asp Ala Trp Arg Trp Ile Leu Ser Gly Gly Glu Asp His Thr Leu Leu 275 280 285 tct acg acg ttt ggc gat gcc ccc tct gga ttc cgc acc atc ggc caa 912 Ser Thr Thr Phe Gly Asp Ala Pro Ser Gly Phe Arg Thr Ile Gly Gln 290 295 300 gtc acc aaa aca cgc cac gaa gac ctc gtc acc gta gat aag aaa acc 960 Val Thr Lys Thr Arg His Glu Asp Leu Val Thr Val Asp Lys Lys Thr 305 310 315 320 ccc gca ttt tcc gat gga tgg aga agc ttc taatgaccaa caccctatgg 1010 Pro Ala Phe Ser Asp Gly Trp Arg Ser Phe 325 330 aat 1013 <210> 524 <211> 330 <212> PRT <213> Corynebacterium glutamicum <400> 524 Thr Leu Ala His Ser Leu Ser Phe Pro Asp Ser Leu Arg Asp Gly Pro 1 5 10 15 Thr Val Gly Asp Leu Gly Glu Phe Glu Val Ile Arg Val Ile Thr Glu 20 25 30 Gln Ala Gly Ser Ser Leu Asn Gly Asp Asp Ala Ala Val Leu Arg His 35 40 45 Ala Ser Pro Asn Ser Arg Ala Val Val Thr Thr Asp Met Leu Val Ala 50 55 60 Gly Arg His Phe Gln Leu Asp Trp Ser Thr Pro Glu Gln Ile Gly Gln 65 70 75 80 Lys Ala Ile Val Gln Asn Phe Ala Asp Ile Glu Ala Met Gly Ala Arg 85 90 95 Pro Val Ala Ala Leu Leu Ala Ile Ser Ala Pro Thr His Thr Pro Val 100 105 110 Glu Phe Val Arg Gly Leu Ala Arg Gly Met Asn Gln Arg Leu Glu Glu 115 120 125 Tyr Ser Ala Glu Leu Val Gly Gly Asp Ile Thr Ser Gly Asp Ser Leu 130 135 140 Val Ile Ala Val Thr Ala Ile Gly Gln Leu Gly Gly Ser Leu Pro Glu 145 150 155 160 Leu Thr Leu Gly Arg Ala Arg Pro Gly Gln Thr Leu Val Ala His Gly 165 170 175 Lys Ile Gly Tyr Ser Ala Ala Gly Leu Ala Leu Leu Gln His Phe Gly 180 185 190 Pro Asp Asn Val Pro Glu His Leu Arg Pro Leu Val Asp Ala His Cys 195 200 205 Ala Pro Val Leu Thr Pro Gly Arg Gly Met Val Ala Arg Ala Ala Gly 210 215 220 Ala Thr Ala Met Thr Asp Asn Ser Asp Gly Leu Ile Val Asp Leu Asn 225 230 235 240 Gln Met Ala Met Lys Ser Gly Val Arg Ile Asp Val Asp Ser Cys Ser 245 250 255 Ile Ser Pro Asp Glu Leu Leu Ser Glu Ala Ala Ser Val Leu Gly Thr 260 265 270 Asp Ala Trp Arg Trp Ile Leu Ser Gly Gly Glu Asp His Thr Leu Leu 275 280 285 Ser Thr Thr Phe Gly Asp Ala Pro Ser Gly Phe Arg Thr Ile Gly Gln 290 295 300 Val Thr Lys Thr Arg His Glu Asp Leu Val Thr Val Asp Lys Lys Thr 305 310 315 320 Pro Ala Phe Ser Asp Gly Trp Arg Ser Phe 325 330 <210> 525 <211> 706 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(706) <223> RXA01352 <400> 525 gtgcccaatg cattgggctg agattgcgcg ctgttgctgc gcgggaccgt tcgaacctgt 60 ctggttaaca ccagcgaagg aagcgaggat tgattgtccc gtg ttt gaa aat cgt 115 Val Phe Glu Asn Arg 1 5 ttt gac ctg cgt tgt tat gtt gtg act ggt gcg ggc tcg gtg gat gag 163 Phe Asp Leu Arg Cys Tyr Val Val Thr Gly Ala Gly Ser Val Asp Glu 10 15 20 gtt gtg cac act gcg tct gct gcg gct cgt ggt ggc gcg ggt gtg gtg 211 Val Val His Thr Ala Ser Ala Ala Ala Arg Gly Gly Ala Gly Val Val 25 30 35 cag gtg cgt tca aag cct att tcg cca gaa gcg atg agg gag ttg gca 259 Gln Val Arg Ser Lys Pro Ile Ser Pro Glu Ala Met Arg Glu Leu Ala 40 45 50 tca aag gtt gcg ctt gag gtt gcg cgg tgc agc cca aca acg agg gtg 307 Ser Lys Val Ala Leu Glu Val Ala Arg Cys Ser Pro Thr Thr Arg Val 55 60 65 ctt atc gac gac cac ctc cac gtt gct tct tcc tta atg cgc gaa gga 355 Leu Ile Asp Asp His Leu His Val Ala Ser Ser Leu Met Arg Glu Gly 70 75 80 85 ctc ccg att cac ggt gtg cat ctt ggg cag gat gat atg tcg gtg ctt 403 Leu Pro Ile His Gly Val His Leu Gly Gln Asp Asp Met Ser Val Leu 90 95 100 gag gct cgt gag ttg ttg ggg cct gag gcg atc att ggg ttg act act 451 Glu Ala Arg Glu Leu Leu Gly Pro Glu Ala Ile Ile Gly Leu Thr Thr 105 110 115 gga acc cta gaa ctt gtg gcg gcg gcg aat gag ctg tcc gat gtg ttg 499 Gly Thr Leu Glu Leu Val Ala Ala Ala Asn Glu Leu Ser Asp Val Leu 120 125 130 gat tac atc ggt gct ggg ccg ttt cgg aag act ccc acc aag gat tca 547 Asp Tyr Ile Gly Ala Gly Pro Phe Arg Lys Thr Pro Thr Lys Asp Ser 135 140 145 ggt cgg cca ccg att ggc ctt gcg ggt tat ccc cct ttg gtg gaa ttg 595 Gly Arg Pro Pro Ile Gly Leu Ala Gly Tyr Pro Pro Leu Val Glu Leu 150 155 160 165 tcc aag gtg ccg atc gtt gcg att ggt gat gtc acc cct gcc gat gtg 643 Ser Lys Val Pro Ile Val Ala Ile Gly Asp Val Thr Pro Ala Asp Val 170 175 180 cgc gct ctc agc gca acc ggt gtg gct ggc gtt gcc atg gtg cgg gct 691 Arg Ala Leu Ser Ala Thr Gly Val Ala Gly Val Ala Met Val Arg Ala 185 190 195 ttt tct gaa tct gat 706 Phe Ser Glu Ser Asp 200 <210> 526 <211> 202 <212> PRT <213> Corynebacterium glutamicum <400> 526 Val Phe Glu Asn Arg Phe Asp Leu Arg Cys Tyr Val Val Thr Gly Ala 1 5 10 15 Gly Ser Val Asp Glu Val Val His Thr Ala Ser Ala Ala Ala Arg Gly 20 25 30 Gly Ala Gly Val Val Gln Val Arg Ser Lys Pro Ile Ser Pro Glu Ala 35 40 45 Met Arg Glu Leu Ala Ser Lys Val Ala Leu Glu Val Ala Arg Cys Ser 50 55 60 Pro Thr Thr Arg Val Leu Ile Asp Asp His Leu His Val Ala Ser Ser 65 70 75 80 Leu Met Arg Glu Gly Leu Pro Ile His Gly Val His Leu Gly Gln Asp 85 90 95 Asp Met Ser Val Leu Glu Ala Arg Glu Leu Leu Gly Pro Glu Ala Ile 100 105 110 Ile Gly Leu Thr Thr Gly Thr Leu Glu Leu Val Ala Ala Ala Asn Glu 115 120 125 Leu Ser Asp Val Leu Asp Tyr Ile Gly Ala Gly Pro Phe Arg Lys Thr 130 135 140 Pro Thr Lys Asp Ser Gly Arg Pro Pro Ile Gly Leu Ala Gly Tyr Pro 145 150 155 160 Pro Leu Val Glu Leu Ser Lys Val Pro Ile Val Ala Ile Gly Asp Val 165 170 175 Thr Pro Ala Asp Val Arg Ala Leu Ser Ala Thr Gly Val Ala Gly Val 180 185 190 Ala Met Val Arg Ala Phe Ser Glu Ser Asp 195 200 <210> 527 <211> 944 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(921) <223> RXA01381 <400> 527 tcc gca ggc gtt gga acc atc acg gtc atc gat gac gac acc gtc gac 48 Ser Ala Gly Val Gly Thr Ile Thr Val Ile Asp Asp Asp Thr Val Asp 1 5 10 15 att tcc aac att cac cgc caa atc ctc ttc ggc gca agc gat gtc ggt 96 Ile Ser Asn Ile His Arg Gln Ile Leu Phe Gly Ala Ser Asp Val Gly 20 25 30 cga ccc aag gtc gag gtt gcc gcc gag cgc ctc aaa gaa ctc caa cca 144 Arg Pro Lys Val Glu Val Ala Ala Glu Arg Leu Lys Glu Leu Gln Pro 35 40 45 gac atc acc gtc aac gcg ttg cac gaa cgg atc act cca gaa aac gcc 192 Asp Ile Thr Val Asn Ala Leu His Glu Arg Ile Thr Pro Glu Asn Ala 50 55 60 tgc gag ctg ctc aat tcc gtg gac ctc gtc tta gac ggc tcc gat tct 240 Cys Glu Leu Leu Asn Ser Val Asp Leu Val Leu Asp Gly Ser Asp Ser 65 70 75 80 ttc tcc aca aaa tac tta gtg tct gat gcc gcc gaa atc acc gga act 288 Phe Ser Thr Lys Tyr Leu Val Ser Asp Ala Ala Glu Ile Thr Gly Thr 85 90 95 ccc ctc atc tgg gca acg gta ctg cgc ttt cac ggc gaa ctg gca ctc 336 Pro Leu Ile Trp Ala Thr Val Leu Arg Phe His Gly Glu Leu Ala Leu 100 105 110 ttc aac tct ggc ccc gac cac cgc gga gtc ggc ctg cgc gac gtc ttc 384 Phe Asn Ser Gly Pro Asp His Arg Gly Val Gly Leu Arg Asp Val Phe 115 120 125 ccc gaa caa ccc tcc gcc gat ttc gtc cct gac tgc gcc acc gct ggt 432 Pro Glu Gln Pro Ser Ala Asp Phe Val Pro Asp Cys Ala Thr Ala Gly 130 135 140 gtt ctt ggc gcc acc aca gcc acc atc ggc gca ctc atg gcc act cac 480 Val Leu Gly Ala Thr Thr Ala Thr Ile Gly Ala Leu Met Ala Thr His 145 150 155 160 gcc atc gga ttt ctc aca gaa atc ggc gac gtc caa cca ggc aca atc 528 Ala Ile Gly Phe Leu Thr Glu Ile Gly Asp Val Gln Pro Gly Thr Ile 165 170 175 ctc tcc tac gac gca ttc ccc gcc gcc acg cgc agc ttc cgc gtc tcc 576 Leu Ser Tyr Asp Ala Phe Pro Ala Ala Thr Arg Ser Phe Arg Val Ser 180 185 190 gcc gac ccg gcg cgc cca ctg gtc acc cgc ctc cgc gcc tcc tac gag 624 Ala Asp Pro Ala Arg Pro Leu Val Thr Arg Leu Arg Ala Ser Tyr Glu 195 200 205 gca gcg cgc acc gat aca act tcg ctt atc gac gcc acc ctc aac ggc 672 Ala Ala Arg Thr Asp Thr Thr Ser Leu Ile Asp Ala Thr Leu Asn Gly 210 215 220 tcc ctc acc gcc ctc gat atc cga gag cca cat gaa gtt ctg ctc aaa 720 Ser Leu Thr Ala Leu Asp Ile Arg Glu Pro His Glu Val Leu Leu Lys 225 230 235 240 gac ctc ccc gag ggc gca acg tca ctg aag ctc ccc tta agc cag atc 768 Asp Leu Pro Glu Gly Ala Thr Ser Leu Lys Leu Pro Leu Ser Gln Ile 245 250 255 acc tcg gac agc gac att tta gag gca ctg tct gga atc gac ggc gac 816 Thr Ser Asp Ser Asp Ile Leu Glu Ala Leu Ser Gly Ile Asp Gly Asp 260 265 270 att ttg gtc tac tgc gct tcg gga atc cgc agt tcc gac ttc atc gac 864 Ile Leu Val Tyr Cys Ala Ser Gly Ile Arg Ser Ser Asp Phe Ile Asp 275 280 285 aac tac tcc cac ctc ggc cac aaa ttt gtg aat ctt ccc ggt ggg gtc 912 Asn Tyr Ser His Leu Gly His Lys Phe Val Asn Leu Pro Gly Gly Val 290 295 300 aac gcg ctg tagctgtcaa tttaagaggc cag 944 Asn Ala Leu 305 <210> 528 <211> 307 <212> PRT <213> Corynebacterium glutamicum <400> 528 Ser Ala Gly Val Gly Thr Ile Thr Val Ile Asp Asp Asp Thr Val Asp 1 5 10 15 Ile Ser Asn Ile His Arg Gln Ile Leu Phe Gly Ala Ser Asp Val Gly 20 25 30 Arg Pro Lys Val Glu Val Ala Ala Glu Arg Leu Lys Glu Leu Gln Pro 35 40 45 Asp Ile Thr Val Asn Ala Leu His Glu Arg Ile Thr Pro Glu Asn Ala 50 55 60 Cys Glu Leu Leu Asn Ser Val Asp Leu Val Leu Asp Gly Ser Asp Ser 65 70 75 80 Phe Ser Thr Lys Tyr Leu Val Ser Asp Ala Ala Glu Ile Thr Gly Thr 85 90 95 Pro Leu Ile Trp Ala Thr Val Leu Arg Phe His Gly Glu Leu Ala Leu 100 105 110 Phe Asn Ser Gly Pro Asp His Arg Gly Val Gly Leu Arg Asp Val Phe 115 120 125 Pro Glu Gln Pro Ser Ala Asp Phe Val Pro Asp Cys Ala Thr Ala Gly 130 135 140 Val Leu Gly Ala Thr Thr Ala Thr Ile Gly Ala Leu Met Ala Thr His 145 150 155 160 Ala Ile Gly Phe Leu Thr Glu Ile Gly Asp Val Gln Pro Gly Thr Ile 165 170 175 Leu Ser Tyr Asp Ala Phe Pro Ala Ala Thr Arg Ser Phe Arg Val Ser 180 185 190 Ala Asp Pro Ala Arg Pro Leu Val Thr Arg Leu Arg Ala Ser Tyr Glu 195 200 205 Ala Ala Arg Thr Asp Thr Thr Ser Leu Ile Asp Ala Thr Leu Asn Gly 210 215 220 Ser Leu Thr Ala Leu Asp Ile Arg Glu Pro His Glu Val Leu Leu Lys 225 230 235 240 Asp Leu Pro Glu Gly Ala Thr Ser Leu Lys Leu Pro Leu Ser Gln Ile 245 250 255 Thr Ser Asp Ser Asp Ile Leu Glu Ala Leu Ser Gly Ile Asp Gly Asp 260 265 270 Ile Leu Val Tyr Cys Ala Ser Gly Ile Arg Ser Ser Asp Phe Ile Asp 275 280 285 Asn Tyr Ser His Leu Gly His Lys Phe Val Asn Leu Pro Gly Gly Val 290 295 300 Asn Ala Leu 305 <210> 529 <211> 259 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(259) <223> RXA01360 <400> 529 gtggcaatca acgccgcggt cgtacccaga tcccagtggt cacgcgccat ttgtgacaac 60 gattccgtag aagttctcac cgcaattcag ggaggttaaa atg ctg cat att gct 115 Met Leu His Ile Ala 1 5 gat aaa act ttc gat tcc cac ctc atc atg ggc acc ggc gga gcc acc 163 Asp Lys Thr Phe Asp Ser His Leu Ile Met Gly Thr Gly Gly Ala Thr 10 15 20 tct cag gcg ttg ctg gag gaa tcc ctt gtc gcc agt gga act caa ttg 211 Ser Gln Ala Leu Leu Glu Glu Ser Leu Val Ala Ser Gly Thr Gln Leu 25 30 35 acc acc gtg gcg atg cgt cga cac caa gca acc acc tct agc gga gaa 259 Thr Thr Val Ala Met Arg Arg His Gln Ala Thr Thr Ser Ser Gly Glu 40 45 50 <210> 530 <211> 53 <212> PRT <213> Corynebacterium glutamicum <400> 530 Met Leu His Ile Ala Asp Lys Thr Phe Asp Ser His Leu Ile Met Gly 1 5 10 15 Thr Gly Gly Ala Thr Ser Gln Ala Leu Leu Glu Glu Ser Leu Val Ala 20 25 30 Ser Gly Thr Gln Leu Thr Thr Val Ala Met Arg Arg His Gln Ala Thr 35 40 45 Thr Ser Ser Gly Glu 50 <210> 531 <211> 629 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(606) <223> RXA01361 <400> 531 gcc gac gct gtg atc tct att gat ggc cac gat ccg tgt ttg acc gtg 48 Ala Asp Ala Val Ile Ser Ile Asp Gly His Asp Pro Cys Leu Thr Val 1 5 10 15 acg atg aat tcg ggg gtg agg gtt gcg tcg aaa agc gtt gtt gtt ttg 96 Thr Met Asn Ser Gly Val Arg Val Ala Ser Lys Ser Val Val Val Leu 20 25 30 gcg gcg ggc ctg ggc gcc gca agc att ccc ggc tgg ttt gag ggc gcg 144 Ala Ala Gly Leu Gly Ala Ala Ser Ile Pro Gly Trp Phe Glu Gly Ala 35 40 45 aac cca ttg cag ttg agg ccg gtg tac ggc gat att gtg cgc gtg cgc 192 Asn Pro Leu Gln Leu Arg Pro Val Tyr Gly Asp Ile Val Arg Val Arg 50 55 60 gtg ccg gag cga ctg cag ccg atg gtc acc aag gtg gtg cgc ggg ttt 240 Val Pro Glu Arg Leu Gln Pro Met Val Thr Lys Val Val Arg Gly Phe 65 70 75 80 gtg gaa gat cgt cag att tat atc att ccg cgt acc gat ggc acc ctc 288 Val Glu Asp Arg Gln Ile Tyr Ile Ile Pro Arg Thr Asp Gly Thr Leu 85 90 95 gcg atc ggc gcg aca agc cgt gag gat cac ccg caa cct cga acg ggc 336 Ala Ile Gly Ala Thr Ser Arg Glu Asp His Pro Gln Pro Arg Thr Gly 100 105 110 gca gtg cat gat ttg cta cgc gat gct atc cgt ttg att ccg ggc att 384 Ala Val His Asp Leu Leu Arg Asp Ala Ile Arg Leu Ile Pro Gly Ile 115 120 125 gaa gaa acc gaa ttt atc gaa gtc acc tgc ggc gcc cgc ccc ggc acc 432 Glu Glu Thr Glu Phe Ile Glu Val Thr Cys Gly Ala Arg Pro Gly Thr 130 135 140 ccg gat gac ctg ccg tac ctg gga tgg gtt gga tcc aat gtg att gcg 480 Pro Asp Asp Leu Pro Tyr Leu Gly Trp Val Gly Ser Asn Val Ile Ala 145 150 155 160 tcc aca gga tat ttc cgc cat gga att ttg ctg tca gcc ctt ggt gca 528 Ser Thr Gly Tyr Phe Arg His Gly Ile Leu Leu Ser Ala Leu Gly Ala 165 170 175 cgc gct gcc gtt gat atg gca acc aac cag cca ctg ttc ccc act ctt 576 Arg Ala Ala Val Asp Met Ala Thr Asn Gln Pro Leu Phe Pro Thr Leu 180 185 190 gat gtg tgc gat ccg ttt cgc cac caa att taaggatttt tcacaagtga 626 Asp Val Cys Asp Pro Phe Arg His Gln Ile 195 200 tta 629 <210> 532 <211> 202 <212> PRT <213> Corynebacterium glutamicum <400> 532 Ala Asp Ala Val Ile Ser Ile Asp Gly His Asp Pro Cys Leu Thr Val 1 5 10 15 Thr Met Asn Ser Gly Val Arg Val Ala Ser Lys Ser Val Val Val Leu 20 25 30 Ala Ala Gly Leu Gly Ala Ala Ser Ile Pro Gly Trp Phe Glu Gly Ala 35 40 45 Asn Pro Leu Gln Leu Arg Pro Val Tyr Gly Asp Ile Val Arg Val Arg 50 55 60 Val Pro Glu Arg Leu Gln Pro Met Val Thr Lys Val Val Arg Gly Phe 65 70 75 80 Val Glu Asp Arg Gln Ile Tyr Ile Ile Pro Arg Thr Asp Gly Thr Leu 85 90 95 Ala Ile Gly Ala Thr Ser Arg Glu Asp His Pro Gln Pro Arg Thr Gly 100 105 110 Ala Val His Asp Leu Leu Arg Asp Ala Ile Arg Leu Ile Pro Gly Ile 115 120 125 Glu Glu Thr Glu Phe Ile Glu Val Thr Cys Gly Ala Arg Pro Gly Thr 130 135 140 Pro Asp Asp Leu Pro Tyr Leu Gly Trp Val Gly Ser Asn Val Ile Ala 145 150 155 160 Ser Thr Gly Tyr Phe Arg His Gly Ile Leu Leu Ser Ala Leu Gly Ala 165 170 175 Arg Ala Ala Val Asp Met Ala Thr Asn Gln Pro Leu Phe Pro Thr Leu 180 185 190 Asp Val Cys Asp Pro Phe Arg His Gln Ile 195 200 <210> 533 <211> 927 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(904) <223> RXA01208 <400> 533 tactaggcac ggggtgccaa ccggatggaa aaattccgga ggctgagaaa acacccgttg 60 aacctgctct agctcgtact agcgaaggga tggccttaac gtg gct aac tcg ttt 115 Val Ala Asn Ser Phe 1 5 ttg gat tct tta act ctt gtt cga caa aac act ccc ctt gtt cag tgt 163 Leu Asp Ser Leu Thr Leu Val Arg Gln Asn Thr Pro Leu Val Gln Cys 10 15 20 ttg acc aac tct gtg gtc atg caa ttc acg gcc aat gtg ttg ctt gcc 211 Leu Thr Asn Ser Val Val Met Gln Phe Thr Ala Asn Val Leu Leu Ala 25 30 35 gcg ggt gcg acc cct gcg atg gtg gat act cca gct gaa tcg gca gaa 259 Ala Gly Ala Thr Pro Ala Met Val Asp Thr Pro Ala Glu Ser Ala Glu 40 45 50 ttc gcc gct gtg gcc aat gga gtg ctc atc aat gcg gga act cct tct 307 Phe Ala Ala Val Ala Asn Gly Val Leu Ile Asn Ala Gly Thr Pro Ser 55 60 65 gcg gag caa tac caa ggc atg acc aag gcc att gag ggt gca cga aaa 355 Ala Glu Gln Tyr Gln Gly Met Thr Lys Ala Ile Glu Gly Ala Arg Lys 70 75 80 85 gct ggc aca cca tgg gtg tta gac cca gtt gct gtg ggt ggg ttg tcg 403 Ala Gly Thr Pro Trp Val Leu Asp Pro Val Ala Val Gly Gly Leu Ser 90 95 100 gag agg acc aag tat gcg gag gga atc gtc gat aag cag cct gcc gca 451 Glu Arg Thr Lys Tyr Ala Glu Gly Ile Val Asp Lys Gln Pro Ala Ala 105 110 115 att cgt gga aac gcc tca gag gtc gtg gcg ctt gcg ggg ctc ggt gcc 499 Ile Arg Gly Asn Ala Ser Glu Val Val Ala Leu Ala Gly Leu Gly Ala 120 125 130 ggt ggg cgc ggc gta gac gcg acc gat tcc gtg gaa gtg gcg ttg gag 547 Gly Gly Arg Gly Val Asp Ala Thr Asp Ser Val Glu Val Ala Leu Glu 135 140 145 gcg gcg caa ttg ttg gcc aag cgc act ggt ggc gtc gtg gct gtc tct 595 Ala Ala Gln Leu Leu Ala Lys Arg Thr Gly Gly Val Val Ala Val Ser 150 155 160 165 ggt gcg gag gac ttg att gtg tct gcg gat cgg gtg acg tgg ttg cgt 643 Gly Ala Glu Asp Leu Ile Val Ser Ala Asp Arg Val Thr Trp Leu Arg 170 175 180 tcg ggg gat ccg atg ttg cag ctg gtg att ggc act gga tgc tct ttg 691 Ser Gly Asp Pro Met Leu Gln Leu Val Ile Gly Thr Gly Cys Ser Leu 185 190 195 ggc gcg ctg aca gct gca tat cta ggc gcc acg gtt gac tca gat att 739 Gly Ala Leu Thr Ala Ala Tyr Leu Gly Ala Thr Val Asp Ser Asp Ile 200 205 210 tcc gcg cac gat gct gtg ttg gct gcg cat gcc cat gtg ggt gct gct 787 Ser Ala His Asp Ala Val Leu Ala Ala His Ala His Val Gly Ala Ala 215 220 225 ggc cag att gca gca cag aag gca tcg gcg cca ggc agc ttt gcg gtg 835 Gly Gln Ile Ala Ala Gln Lys Ala Ser Ala Pro Gly Ser Phe Ala Val 230 235 240 245 gcg ttt att gat gcg ctt tat gac gtg gat gcc cag gct gtg gcc tcg 883 Ala Phe Ile Asp Ala Leu Tyr Asp Val Asp Ala Gln Ala Val Ala Ser 250 255 260 ttg gtt gat gtg cga gag gcc tgaaaagtac gtgactgatt ttt 927 Leu Val Asp Val Arg Glu Ala 265 <210> 534 <211> 268 <212> PRT <213> Corynebacterium glutamicum <400> 534 Val Ala Asn Ser Phe Leu Asp Ser Leu Thr Leu Val Arg Gln Asn Thr 1 5 10 15 Pro Leu Val Gln Cys Leu Thr Asn Ser Val Val Met Gln Phe Thr Ala 20 25 30 Asn Val Leu Leu Ala Ala Gly Ala Thr Pro Ala Met Val Asp Thr Pro 35 40 45 Ala Glu Ser Ala Glu Phe Ala Ala Val Ala Asn Gly Val Leu Ile Asn 50 55 60 Ala Gly Thr Pro Ser Ala Glu Gln Tyr Gln Gly Met Thr Lys Ala Ile 65 70 75 80 Glu Gly Ala Arg Lys Ala Gly Thr Pro Trp Val Leu Asp Pro Val Ala 85 90 95 Val Gly Gly Leu Ser Glu Arg Thr Lys Tyr Ala Glu Gly Ile Val Asp 100 105 110 Lys Gln Pro Ala Ala Ile Arg Gly Asn Ala Ser Glu Val Val Ala Leu 115 120 125 Ala Gly Leu Gly Ala Gly Gly Arg Gly Val Asp Ala Thr Asp Ser Val 130 135 140 Glu Val Ala Leu Glu Ala Ala Gln Leu Leu Ala Lys Arg Thr Gly Gly 145 150 155 160 Val Val Ala Val Ser Gly Ala Glu Asp Leu Ile Val Ser Ala Asp Arg 165 170 175 Val Thr Trp Leu Arg Ser Gly Asp Pro Met Leu Gln Leu Val Ile Gly 180 185 190 Thr Gly Cys Ser Leu Gly Ala Leu Thr Ala Ala Tyr Leu Gly Ala Thr 195 200 205 Val Asp Ser Asp Ile Ser Ala His Asp Ala Val Leu Ala Ala His Ala 210 215 220 His Val Gly Ala Ala Gly Gln Ile Ala Ala Gln Lys Ala Ser Ala Pro 225 230 235 240 Gly Ser Phe Ala Val Ala Phe Ile Asp Ala Leu Tyr Asp Val Asp Ala 245 250 255 Gln Ala Val Ala Ser Leu Val Asp Val Arg Glu Ala 260 265 <210> 535 <211> 1023 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1000) <223> RXA00838 <400> 535 tcgtctaata gtgctgccaa tccaccggcc attgatgact cctttgtaga gaaggggtag 60 tgcttacaaa tcttatctgt gctcaggcaa gatagcaggt atg aaa att gcg atc 115 Met Lys Ile Ala Ile 1 5 gtt ggc gct ggt gca gtt ggt gga tat ttc gga gcg ttg tta caa gaa 163 Val Gly Ala Gly Ala Val Gly Gly Tyr Phe Gly Ala Leu Leu Gln Glu 10 15 20 tct ggt gca gat atc acg atg gtt gca cgt gga cga aca tta gaa gcc 211 Ser Gly Ala Asp Ile Thr Met Val Ala Arg Gly Arg Thr Leu Glu Ala 25 30 35 ttg aag tct aaa gga ctc cac atc aac gat gca aga ggc gaa cgc tac 259 Leu Lys Ser Lys Gly Leu His Ile Asn Asp Ala Arg Gly Glu Arg Tyr 40 45 50 gta cca att cct gca gtt gcg agc gtg caa gaa cta aaa gat gca gat 307 Val Pro Ile Pro Ala Val Ala Ser Val Gln Glu Leu Lys Asp Ala Asp 55 60 65 gta gtg atg att gct act aaa gca tta tcg cgg tct tta gat ctc gct 355 Val Val Met Ile Ala Thr Lys Ala Leu Ser Arg Ser Leu Asp Leu Ala 70 75 80 85 gaa ctt ttg ggt ggg ata cct gcg aat tcg gtg gtc gcg att act cag 403 Glu Leu Leu Gly Gly Ile Pro Ala Asn Ser Val Val Ala Ile Thr Gln 90 95 100 aat tcg att gaa tct gct gat cta gca gcg aag agt atc ggt gct gat 451 Asn Ser Ile Glu Ser Ala Asp Leu Ala Ala Lys Ser Ile Gly Ala Asp 105 110 115 cgt gtg tgg cct ggt gtg gtt cgt ggg ttc ttt gtt cat gag ggg cca 499 Arg Val Trp Pro Gly Val Val Arg Gly Phe Phe Val His Glu Gly Pro 120 125 130 gcc tca gtg tca tac aag gga ggc cca ctg tcc tac acg ttt ggt gat 547 Ala Ser Val Ser Tyr Lys Gly Gly Pro Leu Ser Tyr Thr Phe Gly Asp 135 140 145 tct ggt gaa ctt tct agg caa ttc gca agc act ctt gaa cag gcc ggt 595 Ser Gly Glu Leu Ser Arg Gln Phe Ala Ser Thr Leu Glu Gln Ala Gly 150 155 160 165 att gac gga gtt ctg cat ccc gat att ttg gtg gat gtg tgg gag aaa 643 Ile Asp Gly Val Leu His Pro Asp Ile Leu Val Asp Val Trp Glu Lys 170 175 180 gcc atg ttc gta gag gtt ttc ggc ggg ttg ggg gct ttc gtc gaa aag 691 Ala Met Phe Val Glu Val Phe Gly Gly Leu Gly Ala Phe Val Glu Lys 185 190 195 caa tta ggt acc ttg cgt acg cat ttt agg gct tcc ctg gaa gcc ttg 739 Gln Leu Gly Thr Leu Arg Thr His Phe Arg Ala Ser Leu Glu Ala Leu 200 205 210 atg gaa gag gtg gct gag gtg gct cgc gcg gca ggt gtt gcg ttg ccg 787 Met Glu Glu Val Ala Glu Val Ala Arg Ala Ala Gly Val Ala Leu Pro 215 220 225 agc gat gcg gtg gag cgc acc atg aat ttt gcg gat cgg atg cct gag 835 Ser Asp Ala Val Glu Arg Thr Met Asn Phe Ala Asp Arg Met Pro Glu 230 235 240 245 aat tcg acg agt tcg atg cag cgt gat ttg gcc gcg gga gtg gct agt 883 Asn Ser Thr Ser Ser Met Gln Arg Asp Leu Ala Ala Gly Val Ala Ser 250 255 260 gag ctt gag gct cag aca ggt gca att gtg cgg gca gcg cac aaa gtg 931 Glu Leu Glu Ala Gln Thr Gly Ala Ile Val Arg Ala Ala His Lys Val 265 270 275 ggt gtg aaa act ccg ctt cat gac ctt att tat gct ggt ctt aag ctg 979 Gly Val Lys Thr Pro Leu His Asp Leu Ile Tyr Ala Gly Leu Lys Leu 280 285 290 aaa gaa gag gaa aat tca ctt tagggataga atcaagatcc atg 1023 Lys Glu Glu Glu Asn Ser Leu 295 300 <210> 536 <211> 300 <212> PRT <213> Corynebacterium glutamicum <400> 536 Met Lys Ile Ala Ile Val Gly Ala Gly Ala Val Gly Gly Tyr Phe Gly 1 5 10 15 Ala Leu Leu Gln Glu Ser Gly Ala Asp Ile Thr Met Val Ala Arg Gly 20 25 30 Arg Thr Leu Glu Ala Leu Lys Ser Lys Gly Leu His Ile Asn Asp Ala 35 40 45 Arg Gly Glu Arg Tyr Val Pro Ile Pro Ala Val Ala Ser Val Gln Glu 50 55 60 Leu Lys Asp Ala Asp Val Val Met Ile Ala Thr Lys Ala Leu Ser Arg 65 70 75 80 Ser Leu Asp Leu Ala Glu Leu Leu Gly Gly Ile Pro Ala Asn Ser Val 85 90 95 Val Ala Ile Thr Gln Asn Ser Ile Glu Ser Ala Asp Leu Ala Ala Lys 100 105 110 Ser Ile Gly Ala Asp Arg Val Trp Pro Gly Val Val Arg Gly Phe Phe 115 120 125 Val His Glu Gly Pro Ala Ser Val Ser Tyr Lys Gly Gly Pro Leu Ser 130 135 140 Tyr Thr Phe Gly Asp Ser Gly Glu Leu Ser Arg Gln Phe Ala Ser Thr 145 150 155 160 Leu Glu Gln Ala Gly Ile Asp Gly Val Leu His Pro Asp Ile Leu Val 165 170 175 Asp Val Trp Glu Lys Ala Met Phe Val Glu Val Phe Gly Gly Leu Gly 180 185 190 Ala Phe Val Glu Lys Gln Leu Gly Thr Leu Arg Thr His Phe Arg Ala 195 200 205 Ser Leu Glu Ala Leu Met Glu Glu Val Ala Glu Val Ala Arg Ala Ala 210 215 220 Gly Val Ala Leu Pro Ser Asp Ala Val Glu Arg Thr Met Asn Phe Ala 225 230 235 240 Asp Arg Met Pro Glu Asn Ser Thr Ser Ser Met Gln Arg Asp Leu Ala 245 250 255 Ala Gly Val Ala Ser Glu Leu Glu Ala Gln Thr Gly Ala Ile Val Arg 260 265 270 Ala Ala His Lys Val Gly Val Lys Thr Pro Leu His Asp Leu Ile Tyr 275 280 285 Ala Gly Leu Lys Leu Lys Glu Glu Glu Asn Ser Leu 290 295 300 <210> 537 <211> 693 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(670) <223> RXA02400 <400> 537 aggtgccccc aacgttgcct gttgactgca aattttccga aagaatccat aaactacttc 60 tttaagtcgc cagattaaag tcgtcaatga aaggacatac atg tct att tcc cgc 115 Met Ser Ile Ser Arg 1 5 acc gtc ttc ggc atc gca gcc acc gca gcc ctg tct gca gct ctc gtt 163 Thr Val Phe Gly Ile Ala Ala Thr Ala Ala Leu Ser Ala Ala Leu Val 10 15 20 gcg tgt tct cca cct cac cag cag gat tcc cca gtc cag cgc acc aat 211 Ala Cys Ser Pro Pro His Gln Gln Asp Ser Pro Val Gln Arg Thr Asn 25 30 35 gag atc ttg act act tct cag aac cca act tct gcg agc agc acc tca 259 Glu Ile Leu Thr Thr Ser Gln Asn Pro Thr Ser Ala Ser Ser Thr Ser 40 45 50 acc tct tcc gca acg act act tcc tca gct cct gtg gaa gag gac gta 307 Thr Ser Ser Ala Thr Thr Thr Ser Ser Ala Pro Val Glu Glu Asp Val 55 60 65 gag atc gtt gtt tca cca gca gcg ttg gtg gac ggt gag cag gtt acc 355 Glu Ile Val Val Ser Pro Ala Ala Leu Val Asp Gly Glu Gln Val Thr 70 75 80 85 ttc gaa atc tct gga ctt gat cca gag ggc ggc tac tac gca gcg atc 403 Phe Glu Ile Ser Gly Leu Asp Pro Glu Gly Gly Tyr Tyr Ala Ala Ile 90 95 100 tgc gat tcc gta gcg aac cct ggt aac cca gtt cct tct tgc acc ggc 451 Cys Asp Ser Val Ala Asn Pro Gly Asn Pro Val Pro Ser Cys Thr Gly 105 110 115 gaa atg gct gat ttc acg tcc cag gca tgg ttg agc aac tcc cag ccc 499 Glu Met Ala Asp Phe Thr Ser Gln Ala Trp Leu Ser Asn Ser Gln Pro 120 125 130 ggc gcg act gta gag atc gca gaa gac ggc acc gca act gtg gag ctt 547 Gly Ala Thr Val Glu Ile Ala Glu Asp Gly Thr Ala Thr Val Glu Leu 135 140 145 gaa gct acc gca acc ggc act ggc ttg gac tgc acc act cag gct tgt 595 Glu Ala Thr Ala Thr Gly Thr Gly Leu Asp Cys Thr Thr Gln Ala Cys 150 155 160 165 gta gcg aag gtc ttc ggc gat cat acc gaa ggt ttc cgc gat gtt gct 643 Val Ala Lys Val Phe Gly Asp His Thr Glu Gly Phe Arg Asp Val Ala 170 175 180 gaa gtc cca gtt act ttc gca gcc gct taagttttct taaaacgcac 690 Glu Val Pro Val Thr Phe Ala Ala Ala 185 190 tca 693 <210> 538 <211> 190 <212> PRT <213> Corynebacterium glutamicum <400> 538 Met Ser Ile Ser Arg Thr Val Phe Gly Ile Ala Ala Thr Ala Ala Leu 1 5 10 15 Ser Ala Ala Leu Val Ala Cys Ser Pro Pro His Gln Gln Asp Ser Pro 20 25 30 Val Gln Arg Thr Asn Glu Ile Leu Thr Thr Ser Gln Asn Pro Thr Ser 35 40 45 Ala Ser Ser Thr Ser Thr Ser Ser Ala Thr Thr Thr Ser Ser Ala Pro 50 55 60 Val Glu Glu Asp Val Glu Ile Val Val Ser Pro Ala Ala Leu Val Asp 65 70 75 80 Gly Glu Gln Val Thr Phe Glu Ile Ser Gly Leu Asp Pro Glu Gly Gly 85 90 95 Tyr Tyr Ala Ala Ile Cys Asp Ser Val Ala Asn Pro Gly Asn Pro Val 100 105 110 Pro Ser Cys Thr Gly Glu Met Ala Asp Phe Thr Ser Gln Ala Trp Leu 115 120 125 Ser Asn Ser Gln Pro Gly Ala Thr Val Glu Ile Ala Glu Asp Gly Thr 130 135 140 Ala Thr Val Glu Leu Glu Ala Thr Ala Thr Gly Thr Gly Leu Asp Cys 145 150 155 160 Thr Thr Gln Ala Cys Val Ala Lys Val Phe Gly Asp His Thr Glu Gly 165 170 175 Phe Arg Asp Val Ala Glu Val Pro Val Thr Phe Ala Ala Ala 180 185 190 <210> 539 <211> 1528 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1528) <223> RXN01209 <400> 539 cagattgcag cacagaaggc atcggcgcca ggcagctttg cggtggcgtt tattgatgcg 60 ctttatgacg tggatgccca ggctgtggcc tcgttggttg atg tgc gag agg cct 115 Met Cys Glu Arg Pro 1 5 gaa aag tac gtg act gat ttt tct ttg tat ctg gtc acc gat ccc gtt 163 Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu Val Thr Asp Pro Val 10 15 20 ttg ggt ggc ggg cca aaa aaa gta gct gga att gtt gac agc gca att 211 Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile Val Asp Ser Ala Ile 25 30 35 tcc ggc gga gtt tct gtg gtg cag ctg cgc gat aag aac tca ggc gtg 259 Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp Lys Asn Ser Gly Val 40 45 50 gaa gat gtt cgt gcg gca gca aag gag ctg aaa gaa ctc tgc gat gct 307 Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys Glu Leu Cys Asp Ala 55 60 65 cgc ggg gtg gcg ctt gtt gtc aac gat tac tta gat atc gcc gtt gag 355 Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu Asp Ile Ala Val Glu 70 75 80 85 ctg ggt ctt cac ctg cac att ggt caa ggc gat aca cct tat acg caa 403 Leu Gly Leu His Leu His Ile Gly Gln Gly Asp Thr Pro Tyr Thr Gln 90 95 100 gca cgg gag ctg ctt cca gct cat ctt gaa ttg ggt ttg agc att gaa 451 Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu Gly Leu Ser Ile Glu 105 110 115 aac ctg gat caa ttg cat gct gtg atc gcg cag tgc gcc gag act ggt 499 Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln Cys Ala Glu Thr Gly 120 125 130 gtg gca ttg ccc gat gtg att ggc att ggt ccg gtg gcc tct act gcg 547 Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro Val Ala Ser Thr Ala 135 140 145 acc aaa cca gat gcg gca ccc gca ttg ggt gtg gag ggc atc gct gag 595 Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val Glu Gly Ile Ala Glu 150 155 160 165 atc gcc gct gta gct caa gac cac ggc atc gca tca gta gct att gga 643 Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala Ser Val Ala Ile Gly 170 175 180 ggc gtt ggt cta cgc aac gcg gcc gaa ctc gct gct acg ccc atc gac 691 Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala Ala Thr Pro Ile Asp 185 190 195 ggt ctg tgc gtg gtc tct gaa atc atg acc gcc gcc aat cca gca gct 739 Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala Ala Asn Pro Ala Ala 200 205 210 gcg gca act cgc ctg cgg act gct ttt caa cct act ttc tcg cct gaa 787 Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro Thr Phe Ser Pro Glu 215 220 225 act caa act gaa ctc tct caa aca gaa ctc caa gga gcc ttc gtg aat 835 Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln Gly Ala Phe Val Asn 230 235 240 245 tcg cct tct gcc cca cgt gtg ttg tct att gca ggc act gat ccc aca 883 Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala Gly Thr Asp Pro Thr 250 255 260 ggt ggt gca ggt att cag gct gat ctg aag tcc att gca gca ggt ggc 931 Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser Ile Ala Ala Gly Gly 265 270 275 ggc tac ggc atg tgc gtt gtg acc tcg ctg gtc gcg caa aac acc cac 979 Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val Ala Gln Asn Thr His 280 285 290 ggc gtc aac acg atc cac acc cca ccc ttg acc ttt ttg gaa gaa cag 1027 Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr Phe Leu Glu Glu Gln 295 300 305 ctg gaa gcg gtc ttt tcc gat gtc acc gtc gat gcc atc aag ctc ggc 1075 Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp Ala Ile Lys Leu Gly 310 315 320 325 atg ttg ggc tct gcc gac acc gtc gat ctg gtg gct tca tgg ctt ggt 1123 Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val Ala Ser Trp Leu Gly 330 335 340 tcc cac gag cac ggt ccc gtg gtg ctt gat ccc gtc atg atc gcc acc 1171 Ser His Glu His Gly Pro Val Val Leu Asp Pro Val Met Ile Ala Thr 345 350 355 agc ggt gat cgc cta ctg gat gcg agc gct gaa gaa tcg ctg cgc cgc 1219 Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu Glu Ser Leu Arg Arg 360 365 370 ctg gcc gtg cac gtc gat gtg gtc acc ccg aat atc ccc gaa ctt gcc 1267 Leu Ala Val His Val Asp Val Val Thr Pro Asn Ile Pro Glu Leu Ala 375 380 385 gtg ttg tgc gac agt gct cct gcc atc acc atg gat gag gcc att gct 1315 Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met Asp Glu Ala Ile Ala 390 395 400 405 cag gct cag gga ttt gcg cgg act cat gac acc atc gtc att gtc aag 1363 Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr Ile Val Ile Val Lys 410 415 420 ggt gga cat ctg act ggc gcg ctt gct gat aac gct gtc gtg cgc ccc 1411 Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn Ala Val Val Arg Pro 425 430 435 gac ggc tcg gtg ttc cag gtg gaa aac ctg cgt gtc aac acc acc aac 1459 Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg Val Asn Thr Thr Asn 440 445 450 tcc cat ggc aca ggc tgt tcg ctc tct gcg tca ctt gcc acc aag atc 1507 Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser Leu Ala Thr Lys Ile 455 460 465 gcc gcc ggc gaa agc gtg gaa 1528 Ala Ala Gly Glu Ser Val Glu 470 475 <210> 540 <211> 476 <212> PRT <213> Corynebacterium glutamicum <400> 540 Met Cys Glu Arg Pro Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu 1 5 10 15 Val Thr Asp Pro Val Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile 20 25 30 Val Asp Ser Ala Ile Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp 35 40 45 Lys Asn Ser Gly Val Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys 50 55 60 Glu Leu Cys Asp Ala Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu 65 70 75 80 Asp Ile Ala Val Glu Leu Gly Leu His Leu His Ile Gly Gln Gly Asp 85 90 95 Thr Pro Tyr Thr Gln Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu 100 105 110 Gly Leu Ser Ile Glu Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln 115 120 125 Cys Ala Glu Thr Gly Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro 130 135 140 Val Ala Ser Thr Ala Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val 145 150 155 160 Glu Gly Ile Ala Glu Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala 165 170 175 Ser Val Ala Ile Gly Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala 180 185 190 Ala Thr Pro Ile Asp Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala 195 200 205 Ala Asn Pro Ala Ala Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro 210 215 220 Thr Phe Ser Pro Glu Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln 225 230 235 240 Gly Ala Phe Val Asn Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala 245 250 255 Gly Thr Asp Pro Thr Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser 260 265 270 Ile Ala Ala Gly Gly Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val 275 280 285 Ala Gln Asn Thr His Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr 290 295 300 Phe Leu Glu Glu Gln Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp 305 310 315 320 Ala Ile Lys Leu Gly Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val 325 330 335 Ala Ser Trp Leu Gly Ser His Glu His Gly Pro Val Val Leu Asp Pro 340 345 350 Val Met Ile Ala Thr Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu 355 360 365 Glu Ser Leu Arg Arg Leu Ala Val His Val Asp Val Val Thr Pro Asn 370 375 380 Ile Pro Glu Leu Ala Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met 385 390 395 400 Asp Glu Ala Ile Ala Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr 405 410 415 Ile Val Ile Val Lys Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn 420 425 430 Ala Val Val Arg Pro Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg 435 440 445 Val Asn Thr Thr Asn Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser 450 455 460 Leu Ala Thr Lys Ile Ala Ala Gly Glu Ser Val Glu 465 470 475 <210> 541 <211> 1528 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1528) <223> FRXA01209 <400> 541 cagattgcag cacagaaggc atcggcgcca ggcagctttg cggtggcgtt tattgatgcg 60 ctttatgacg tggatgccca ggctgtggcc tcgttggttg atg tgc gag agg cct 115 Met Cys Glu Arg Pro 1 5 gaa aag tac gtg act gat ttt tct ttg tat ctg gtc acc gat ccc gtt 163 Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu Val Thr Asp Pro Val 10 15 20 ttg ggt ggc ggg cca aaa aaa gta gct gga att gtt gac agc gca att 211 Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile Val Asp Ser Ala Ile 25 30 35 tcc ggc gga gtt tct gtg gtg cag ctg cgc gat aag aac tca ggc gtg 259 Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp Lys Asn Ser Gly Val 40 45 50 gaa gat gtt cgt gcg gca gca aag gag ctg aaa gaa ctc tgc gat gct 307 Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys Glu Leu Cys Asp Ala 55 60 65 cgc ggg gtg gcg ctt gtt gtc aac gat tac tta gat atc gcc gtt gag 355 Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu Asp Ile Ala Val Glu 70 75 80 85 ctg ggt ctt cac ctg cac att ggt caa ggc gat aca cct tat acg caa 403 Leu Gly Leu His Leu His Ile Gly Gln Gly Asp Thr Pro Tyr Thr Gln 90 95 100 gca cgg gag ctg ctt cca gct cat ctt gaa ttg ggt ttg agc att gaa 451 Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu Gly Leu Ser Ile Glu 105 110 115 aac ctg gat caa ttg cat gct gtg atc gcg cag tgc gcc gag act ggt 499 Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln Cys Ala Glu Thr Gly 120 125 130 gtg gca ttg ccc gat gtg att ggc att ggt ccg gtg gcc tct act gcg 547 Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro Val Ala Ser Thr Ala 135 140 145 acc aaa cca gat gcg gca ccc gca ttg ggt gtg gag ggc atc gct gag 595 Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val Glu Gly Ile Ala Glu 150 155 160 165 atc gcc gct gta gct caa gac cac ggc atc gca tca gta gct att gga 643 Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala Ser Val Ala Ile Gly 170 175 180 ggc gtt ggt cta cgc aac gcg gcc gaa ctc gct gct acg ccc atc gac 691 Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala Ala Thr Pro Ile Asp 185 190 195 ggt ctg tgc gtg gtc tct gaa atc atg acc gcc gcc aat cca gca gct 739 Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala Ala Asn Pro Ala Ala 200 205 210 gcg gca act cgc ctg cgg act gct ttt caa cct act ttc tcg cct gaa 787 Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro Thr Phe Ser Pro Glu 215 220 225 act caa act gaa ctc tct caa aca gaa ctc caa gga gcc ttc gtg aat 835 Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln Gly Ala Phe Val Asn 230 235 240 245 tcg cct tct gcc cca cgt gtg ttg tct att gca ggc act gat ccc aca 883 Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala Gly Thr Asp Pro Thr 250 255 260 ggt ggt gca ggt att cag gct gat ctg aag tcc att gca gca ggt ggc 931 Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser Ile Ala Ala Gly Gly 265 270 275 ggc tac ggc atg tgc gtt gtg acc tcg ctg gtc gcg caa aac acc cac 979 Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val Ala Gln Asn Thr His 280 285 290 ggc gtc aac acg atc cac acc cca ccc ttg acc ttt ttg gaa gaa cag 1027 Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr Phe Leu Glu Glu Gln 295 300 305 ctg gaa gcg gtc ttt tcc gat gtc acc gtc gat gcc atc aag ctc ggc 1075 Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp Ala Ile Lys Leu Gly 310 315 320 325 atg ttg ggc tct gcc gac acc gtc gat ctg gtg gct tca tgg ctt ggt 1123 Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val Ala Ser Trp Leu Gly 330 335 340 tcc cac gag cac ggt ccc gtg gtg ctt gat ccc gtc atg atc gcc acc 1171 Ser His Glu His Gly Pro Val Val Leu Asp Pro Val Met Ile Ala Thr 345 350 355 agc ggt gat cgc cta ctg gat gcg agc gct gaa gaa tcg ctg cgc cgc 1219 Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu Glu Ser Leu Arg Arg 360 365 370 ctg gcc gtg cac gtc gat gtg gtc acc ccg aat atc ccc gaa ctt gcc 1267 Leu Ala Val His Val Asp Val Val Thr Pro Asn Ile Pro Glu Leu Ala 375 380 385 gtg ttg tgc gac agt gct cct gcc atc acc atg gat gag gcc att gct 1315 Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met Asp Glu Ala Ile Ala 390 395 400 405 cag gct cag gga ttt gcg cgg act cat gac acc atc gtc att gtc aag 1363 Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr Ile Val Ile Val Lys 410 415 420 ggt gga cat ctg act ggc gcg ctt gct gat aac gct gtc gtg cgc ccc 1411 Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn Ala Val Val Arg Pro 425 430 435 gac ggc tcg gtg ttc cag gtg gaa aac ctg cgt gtc aac acc acc aac 1459 Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg Val Asn Thr Thr Asn 440 445 450 tcc cat ggc aca ggc tgt tcg ctc tct gcg tca ctt gcc acc aag atc 1507 Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser Leu Ala Thr Lys Ile 455 460 465 gcc gcc ggc gaa agc gtg gaa 1528 Ala Ala Gly Glu Ser Val Glu 470 475 <210> 542 <211> 476 <212> PRT <213> Corynebacterium glutamicum <400> 542 Met Cys Glu Arg Pro Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu 1 5 10 15 Val Thr Asp Pro Val Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile 20 25 30 Val Asp Ser Ala Ile Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp 35 40 45 Lys Asn Ser Gly Val Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys 50 55 60 Glu Leu Cys Asp Ala Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu 65 70 75 80 Asp Ile Ala Val Glu Leu Gly Leu His Leu His Ile Gly Gln Gly Asp 85 90 95 Thr Pro Tyr Thr Gln Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu 100 105 110 Gly Leu Ser Ile Glu Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln 115 120 125 Cys Ala Glu Thr Gly Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro 130 135 140 Val Ala Ser Thr Ala Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val 145 150 155 160 Glu Gly Ile Ala Glu Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala 165 170 175 Ser Val Ala Ile Gly Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala 180 185 190 Ala Thr Pro Ile Asp Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala 195 200 205 Ala Asn Pro Ala Ala Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro 210 215 220 Thr Phe Ser Pro Glu Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln 225 230 235 240 Gly Ala Phe Val Asn Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala 245 250 255 Gly Thr Asp Pro Thr Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser 260 265 270 Ile Ala Ala Gly Gly Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val 275 280 285 Ala Gln Asn Thr His Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr 290 295 300 Phe Leu Glu Glu Gln Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp 305 310 315 320 Ala Ile Lys Leu Gly Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val 325 330 335 Ala Ser Trp Leu Gly Ser His Glu His Gly Pro Val Val Leu Asp Pro 340 345 350 Val Met Ile Ala Thr Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu 355 360 365 Glu Ser Leu Arg Arg Leu Ala Val His Val Asp Val Val Thr Pro Asn 370 375 380 Ile Pro Glu Leu Ala Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met 385 390 395 400 Asp Glu Ala Ile Ala Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr 405 410 415 Ile Val Ile Val Lys Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn 420 425 430 Ala Val Val Arg Pro Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg 435 440 445 Val Asn Thr Thr Asn Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser 450 455 460 Leu Ala Thr Lys Ile Ala Ala Gly Glu Ser Val Glu 465 470 475 <210> 543 <211> 723 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(700) <223> RXN01413 <400> 543 tttgccctat tggaagaagt aaattccaca ccttcacttt ccaatacttc ttttggtgag 60 cgggtttcct cagcgtttaa ccatctgaaa ccatctgaga ttg acc cat ctg ttc 115 Leu Thr His Leu Phe 1 5 tta gaa ctc gat gag cgt tta gta ctg ggt gtt cag caa gat ggt tac 163 Leu Glu Leu Asp Glu Arg Leu Val Leu Gly Val Gln Gln Asp Gly Tyr 10 15 20 caa tgg act gag cat ttg ttc cgg ctg cca ctg caa cat ctc cgt aac 211 Gln Trp Thr Glu His Leu Phe Arg Leu Pro Leu Gln His Leu Arg Asn 25 30 35 tcg ccc aat gac ctg cag gga ttg aag ata cga tgg tgt gaa ctt tat 259 Ser Pro Asn Asp Leu Gln Gly Leu Lys Ile Arg Trp Cys Glu Leu Tyr 40 45 50 tcc aca acg ggg aaa gat caa ggg gta gaa ctt ctg cct caa gca acc 307 Ser Thr Thr Gly Lys Asp Gln Gly Val Glu Leu Leu Pro Gln Ala Thr 55 60 65 gtc gtt acc cca aat aac ttc gag gct tcc acc ctc tcc ggc ctt gag 355 Val Val Thr Pro Asn Asn Phe Glu Ala Ser Thr Leu Ser Gly Leu Glu 70 75 80 85 aag ctt gag acc gtc gag gac ctc aag gag gct gcc cgc ctc att tat 403 Lys Leu Glu Thr Val Glu Asp Leu Lys Glu Ala Ala Arg Leu Ile Tyr 90 95 100 gag caa ggc ccc cag tac gta gtc gtc aag ggt ggc atg gac ttc ccc 451 Glu Gln Gly Pro Gln Tyr Val Val Val Lys Gly Gly Met Asp Phe Pro 105 110 115 ggc gag aac gcc gtg gat gtg ctt ttc gac gga tcc tcc tac cac gtc 499 Gly Glu Asn Ala Val Asp Val Leu Phe Asp Gly Ser Ser Tyr His Val 120 125 130 ttc tct gag cca aag att ggt gaa gag cgc gtt tcc ggc gca gtc tgc 547 Phe Ser Glu Pro Lys Ile Gly Glu Glu Arg Val Ser Gly Ala Val Cys 135 140 145 acc ttc gca gct gtt atc acc gca gag cta gca aag ggt gct gag gtt 595 Thr Phe Ala Ala Val Ile Thr Ala Glu Leu Ala Lys Gly Ala Glu Val 150 155 160 165 gta gac cca gtg gca acc gca aag cgt gtg gtc acc cgt gcg gtt caa 643 Val Asp Pro Val Ala Thr Ala Lys Arg Val Val Thr Arg Ala Val Gln 170 175 180 gat gct gtt gca tcc aac gca cct ttt acc tcc gta tgg ctt gct gag 691 Asp Ala Val Ala Ser Asn Ala Pro Phe Thr Ser Val Trp Leu Ala Glu 185 190 195 gac aac aag tagagtttta aaataccgat caa 723 Asp Asn Lys 200 <210> 544 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 544 Leu Thr His Leu Phe Leu Glu Leu Asp Glu Arg Leu Val Leu Gly Val 1 5 10 15 Gln Gln Asp Gly Tyr Gln Trp Thr Glu His Leu Phe Arg Leu Pro Leu 20 25 30 Gln His Leu Arg Asn Ser Pro Asn Asp Leu Gln Gly Leu Lys Ile Arg 35 40 45 Trp Cys Glu Leu Tyr Ser Thr Thr Gly Lys Asp Gln Gly Val Glu Leu 50 55 60 Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn Phe Glu Ala Ser Thr 65 70 75 80 Leu Ser Gly Leu Glu Lys Leu Glu Thr Val Glu Asp Leu Lys Glu Ala 85 90 95 Ala Arg Leu Ile Tyr Glu Gln Gly Pro Gln Tyr Val Val Val Lys Gly 100 105 110 Gly Met Asp Phe Pro Gly Glu Asn Ala Val Asp Val Leu Phe Asp Gly 115 120 125 Ser Ser Tyr His Val Phe Ser Glu Pro Lys Ile Gly Glu Glu Arg Val 130 135 140 Ser Gly Ala Val Cys Thr Phe Ala Ala Val Ile Thr Ala Glu Leu Ala 145 150 155 160 Lys Gly Ala Glu Val Val Asp Pro Val Ala Thr Ala Lys Arg Val Val 165 170 175 Thr Arg Ala Val Gln Asp Ala Val Ala Ser Asn Ala Pro Phe Thr Ser 180 185 190 Val Trp Leu Ala Glu Asp Asn Lys 195 200 <210> 545 <211> 795 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(772) <223> RXN01617 <400> 545 tcagaagcta ccggcggcgc cggcatccag gttgatttga agaccttcca gcatttaaga 60 tgtttatggc attgggtcca tcacatgctt gggtggcctt ttg atc cta aag aca 115 Leu Ile Leu Lys Thr 1 5 act gga atc acc gtt ttg tcc cgg ttt gat gcg cag gtt atc gct aat 163 Thr Gly Ile Thr Val Leu Ser Arg Phe Asp Ala Gln Val Ile Ala Asn 10 15 20 cag att gag gcc gcc acc gca gcg cac gat ctt gat gtg gtg aag atc 211 Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu Asp Val Val Lys Ile 25 30 35 ggt atg ttg ggt act cct gca acg atc gat act gtg gca acc gct ttg 259 Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr Val Ala Thr Ala Leu 40 45 50 gag gaa aac agc ttc aag cac gtt gtc cta gac ccg gta ctg atc tgc 307 Glu Glu Asn Ser Phe Lys His Val Val Leu Asp Pro Val Leu Ile Cys 55 60 65 aag ggc cag gag ccc ggc gcg gca ctt gat act gac act gcc ctt cgc 355 Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr Asp Thr Ala Leu Arg 70 75 80 85 gcg aag gtg ctg cca cag gca acc gtg gtt act cca aac aac ttc gag 403 Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn Phe Glu 90 95 100 gcc acc acc ctg tct ggc cta gac aag ctg gag acc atc gac gac ctg 451 Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu Thr Ile Asp Asp Leu 105 110 115 aag gaa gca gcc cgc ctc att cat gag caa gga cct cag tac gtc gtt 499 Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly Pro Gln Tyr Val Val 120 125 130 gtt aag ggt ggc atc gac ttc cca ggc gac aac gct gtg gac gta ctt 547 Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn Ala Val Asp Val Leu 135 140 145 ttc gac ggc acc gac tac cac gtg ttc tct gaa cca aag atc ggc gac 595 Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu Pro Lys Ile Gly Asp 150 155 160 165 gag cgc gtc tcc ggc gct ggc tgt acc ttc gca gct gtc atc acc gca 643 Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala Ala Val Ile Thr Ala 170 175 180 gag ctg gcc aag ggc aac tct gcc gtt gat gca gtg acc acc gct aag 691 Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala Val Thr Thr Ala Lys 185 190 195 cgc gta gtc acc cgc gca gtg aag gac gct gtc gca tcc aac gca ccg 739 Arg Val Val Thr Arg Ala Val Lys Asp Ala Val Ala Ser Asn Ala Pro 200 205 210 ttt acc tct gtg tgg ttg gcg gaa gac aac aag tagaaatctt aaacaagctc 792 Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 215 220 cct 795 <210> 546 <211> 224 <212> PRT <213> Corynebacterium glutamicum <400> 546 Leu Ile Leu Lys Thr Thr Gly Ile Thr Val Leu Ser Arg Phe Asp Ala 1 5 10 15 Gln Val Ile Ala Asn Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu 20 25 30 Asp Val Val Lys Ile Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr 35 40 45 Val Ala Thr Ala Leu Glu Glu Asn Ser Phe Lys His Val Val Leu Asp 50 55 60 Pro Val Leu Ile Cys Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr 65 70 75 80 Asp Thr Ala Leu Arg Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr 85 90 95 Pro Asn Asn Phe Glu Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu 100 105 110 Thr Ile Asp Asp Leu Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly 115 120 125 Pro Gln Tyr Val Val Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn 130 135 140 Ala Val Asp Val Leu Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu 145 150 155 160 Pro Lys Ile Gly Asp Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala 165 170 175 Ala Val Ile Thr Ala Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala 180 185 190 Val Thr Thr Ala Lys Arg Val Val Thr Arg Ala Val Lys Asp Ala Val 195 200 205 Ala Ser Asn Ala Pro Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 210 215 220 <210> 547 <211> 638 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(615) <223> FRXA01617 <400> 547 gct aat cag att gag gcc gcc acc gca gcg cac gat ctt gat gtg gtg 48 Ala Asn Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu Asp Val Val 1 5 10 15 aag atc ggt atg ttg ggt act cct gca acg atc gat act gtg gca acc 96 Lys Ile Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr Val Ala Thr 20 25 30 gct ttg gag gaa aac agc ttc aag cac gtt gtc cta gac ccg gta ctg 144 Ala Leu Glu Glu Asn Ser Phe Lys His Val Val Leu Asp Pro Val Leu 35 40 45 atc tgc aag ggc cag gag ccc ggc gcg gca ctt gat act gac act gcc 192 Ile Cys Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr Asp Thr Ala 50 55 60 ctt cgc gcg aag gtg ctg cca cag gca acc gtg gtt act cca aac aac 240 Leu Arg Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn 65 70 75 80 ttc gag gcc acc acc ctg tct ggc cta gac aag ctg gag acc atc gac 288 Phe Glu Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu Thr Ile Asp 85 90 95 gac ctg aag gaa gca gcc cgc ctc att cat gag caa gga cct cag tac 336 Asp Leu Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly Pro Gln Tyr 100 105 110 gtc gtt gtt aag ggt ggc atc gac ttc cca ggc gac aac gct gtg gac 384 Val Val Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn Ala Val Asp 115 120 125 gta ctt ttc gac ggc acc gac tac cac gtg ttc tct gaa cca aag atc 432 Val Leu Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu Pro Lys Ile 130 135 140 ggc gac gag cgc gtc tcc ggc gct ggc tgt acc ttc gca gct gtc atc 480 Gly Asp Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala Ala Val Ile 145 150 155 160 acc gca gag ctg gcc aag ggc aac tct gcc gtt gat gca gtg acc acc 528 Thr Ala Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala Val Thr Thr 165 170 175 gct aag cgc gta gtc acc cgc gca gtg aag gac gct gtc gca tcc aac 576 Ala Lys Arg Val Val Thr Arg Ala Val Lys Asp Ala Val Ala Ser Asn 180 185 190 gca ccg ttt acc tct gtg tgg ttg gcg gaa gac aac aag tagaaatctt 625 Ala Pro Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 195 200 205 aaacaagctc cct 638 <210> 548 <211> 205 <212> PRT <213> Corynebacterium glutamicum <400> 548 Ala Asn Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu Asp Val Val 1 5 10 15 Lys Ile Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr Val Ala Thr 20 25 30 Ala Leu Glu Glu Asn Ser Phe Lys His Val Val Leu Asp Pro Val Leu 35 40 45 Ile Cys Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr Asp Thr Ala 50 55 60 Leu Arg Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn 65 70 75 80 Phe Glu Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu Thr Ile Asp 85 90 95 Asp Leu Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly Pro Gln Tyr 100 105 110 Val Val Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn Ala Val Asp 115 120 125 Val Leu Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu Pro Lys Ile 130 135 140 Gly Asp Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala Ala Val Ile 145 150 155 160 Thr Ala Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala Val Thr Thr 165 170 175 Ala Lys Arg Val Val Thr Arg Ala Val Lys Asp Ala Val Ala Ser Asn 180 185 190 Ala Pro Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 195 200 205 <210> 549 <211> 915 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(892) <223> RXS01807 <400> 549 gctcaccgag ctggacacca agctccgcgc agtgcaggaa gaacacggcg agctggaaat 60 gcagtggctg gaactcggcg aggaaatcga gggctagttc atg ccg tcg gca ggc 115 Met Pro Ser Ala Gly 1 5 gag gag att tta gag cag cgc gca cag ctg gag ttt gat cag cgc cgc 163 Glu Glu Ile Leu Glu Gln Arg Ala Gln Leu Glu Phe Asp Gln Arg Arg 10 15 20 gcc gat gtg gtg atg atc ggc agc cag gtg gtt tat ggt tcc gtg ggg 211 Ala Asp Val Val Met Ile Gly Ser Gln Val Val Tyr Gly Ser Val Gly 25 30 35 ctc agt gct gcc att ccg gtg atg cac aac gaa ggc ctc cgc gtg gtc 259 Leu Ser Ala Ala Ile Pro Val Met His Asn Glu Gly Leu Arg Val Val 40 45 50 gct gtc ccc acc gtg gtg tta agt tcc atg ccg cgt tat gca agt tct 307 Ala Val Pro Thr Val Val Leu Ser Ser Met Pro Arg Tyr Ala Ser Ser 55 60 65 cac cgc cag ccg atg tcg gac caa tgg ctc gcc gac gcg ctg caa gac 355 His Arg Gln Pro Met Ser Asp Gln Trp Leu Ala Asp Ala Leu Gln Asp 70 75 80 85 ctg gtg gat ctg ggg att atc gat gag gtt tcc acc att tcc acc ggc 403 Leu Val Asp Leu Gly Ile Ile Asp Glu Val Ser Thr Ile Ser Thr Gly 90 95 100 tat ttt acc tcc gct tct cag gtg cgt gtg gtc gct gcg tgg ctg cag 451 Tyr Phe Thr Ser Ala Ser Gln Val Arg Val Val Ala Ala Trp Leu Gln 105 110 115 aaa atc cgc gaa acc cat ccg cat gtg cgc atc gtg gtg gat ccc atc 499 Lys Ile Arg Glu Thr His Pro His Val Arg Ile Val Val Asp Pro Ile 120 125 130 atg ggg gac agt gac gtg gga att tat gtc gcc gac gag atc gca acc 547 Met Gly Asp Ser Asp Val Gly Ile Tyr Val Ala Asp Glu Ile Ala Thr 135 140 145 gcc atc tgc cag gac tta tgc cct ctg gct acc gga atc att ccc aat 595 Ala Ile Cys Gln Asp Leu Cys Pro Leu Ala Thr Gly Ile Ile Pro Asn 150 155 160 165 gct ttc gag ctc tcc cac atg gtt ggc tcc ggc gat ccg cgc tcg ctg 643 Ala Phe Glu Leu Ser His Met Val Gly Ser Gly Asp Pro Arg Ser Leu 170 175 180 ctc ggc ccg ttt ggc gag tgg atc atc atc acc agc gcc act gaa act 691 Leu Gly Pro Phe Gly Glu Trp Ile Ile Ile Thr Ser Ala Thr Glu Thr 185 190 195 gtg ggc acc acc gtc acc cgc atc gtc acc cgt gac agc gtc cag gaa 739 Val Gly Thr Thr Val Thr Arg Ile Val Thr Arg Asp Ser Val Gln Glu 200 205 210 atc gcc tcc gcc acc gtc gat acc acg gcc aaa ggg gca ggc gac gtc 787 Ile Ala Ser Ala Thr Val Asp Thr Thr Ala Lys Gly Ala Gly Asp Val 215 220 225 tac gcc gca gca tta atc gcc gcc ctg cat aaa gat ttt tcg ctt atc 835 Tyr Ala Ala Ala Leu Ile Ala Ala Leu His Lys Asp Phe Ser Leu Ile 230 235 240 245 gac gcc gcc agc cac gca tcc aac acc gtc tgc gcc ggc ctg cag acc 883 Asp Ala Ala Ser His Ala Ser Asn Thr Val Cys Ala Gly Leu Gln Thr 250 255 260 aaa gcg ctt taggtttcgt ccgtctctga cag 915 Lys Ala Leu <210> 550 <211> 264 <212> PRT <213> Corynebacterium glutamicum <400> 550 Met Pro Ser Ala Gly Glu Glu Ile Leu Glu Gln Arg Ala Gln Leu Glu 1 5 10 15 Phe Asp Gln Arg Arg Ala Asp Val Val Met Ile Gly Ser Gln Val Val 20 25 30 Tyr Gly Ser Val Gly Leu Ser Ala Ala Ile Pro Val Met His Asn Glu 35 40 45 Gly Leu Arg Val Val Ala Val Pro Thr Val Val Leu Ser Ser Met Pro 50 55 60 Arg Tyr Ala Ser Ser His Arg Gln Pro Met Ser Asp Gln Trp Leu Ala 65 70 75 80 Asp Ala Leu Gln Asp Leu Val Asp Leu Gly Ile Ile Asp Glu Val Ser 85 90 95 Thr Ile Ser Thr Gly Tyr Phe Thr Ser Ala Ser Gln Val Arg Val Val 100 105 110 Ala Ala Trp Leu Gln Lys Ile Arg Glu Thr His Pro His Val Arg Ile 115 120 125 Val Val Asp Pro Ile Met Gly Asp Ser Asp Val Gly Ile Tyr Val Ala 130 135 140 Asp Glu Ile Ala Thr Ala Ile Cys Gln Asp Leu Cys Pro Leu Ala Thr 145 150 155 160 Gly Ile Ile Pro Asn Ala Phe Glu Leu Ser His Met Val Gly Ser Gly 165 170 175 Asp Pro Arg Ser Leu Leu Gly Pro Phe Gly Glu Trp Ile Ile Ile Thr 180 185 190 Ser Ala Thr Glu Thr Val Gly Thr Thr Val Thr Arg Ile Val Thr Arg 195 200 205 Asp Ser Val Gln Glu Ile Ala Ser Ala Thr Val Asp Thr Thr Ala Lys 210 215 220 Gly Ala Gly Asp Val Tyr Ala Ala Ala Leu Ile Ala Ala Leu His Lys 225 230 235 240 Asp Phe Ser Leu Ile Asp Ala Ala Ser His Ala Ser Asn Thr Val Cys 245 250 255 Ala Gly Leu Gln Thr Lys Ala Leu 260 <210> 551 <211> 622 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(622) <223> RXC01021 <400> 551 cgagaggctt ttttggctct aagcctttta gtcgtgcgaa cgaaatctta agcagcctcg 60 gtgccaccga gatcgattgg tcgctgtaag gtatctgatt atg tcc agt tcc gaa 115 Met Ser Ser Ser Glu 1 5 agc tcg cgt tcc gaa ggc tcg cag cca gca ccg tct gta cag cct gaa 163 Ser Ser Arg Ser Glu Gly Ser Gln Pro Ala Pro Ser Val Gln Pro Glu 10 15 20 cgc cgt gct gat tca acg ggg gct cct gcg gca gct tcc aag gaa gct 211 Arg Arg Ala Asp Ser Thr Gly Ala Pro Ala Ala Ala Ser Lys Glu Ala 25 30 35 tcc caa caa atg gac gct gcc gga gtt ctt gag tgg gcc agg acc gct 259 Ser Gln Gln Met Asp Ala Ala Gly Val Leu Glu Trp Ala Arg Thr Ala 40 45 50 gtc gag cag ctt tct gaa cgt cgt gca gag atc aat gca ctg aat gtc 307 Val Glu Gln Leu Ser Glu Arg Arg Ala Glu Ile Asn Ala Leu Asn Val 55 60 65 ttt cct gtt cca gat gca gac act gga tca aac atg acc tac acc atg 355 Phe Pro Val Pro Asp Ala Asp Thr Gly Ser Asn Met Thr Tyr Thr Met 70 75 80 85 aca gct gcg ttg gat gaa gcg ctg aaa ctg ggg gag ttg ggt gat gtc 403 Thr Ala Ala Leu Asp Glu Ala Leu Lys Leu Gly Glu Leu Gly Asp Val 90 95 100 gca agg att act gag gct ttg gct gtt ggt tct gtg cgt gga gcc cga 451 Ala Arg Ile Thr Glu Ala Leu Ala Val Gly Ser Val Arg Gly Ala Arg 105 110 115 gga aat tct gga gta gtc ctt agt cag gtc ctt cgc gct att gct cag 499 Gly Asn Ser Gly Val Val Leu Ser Gln Val Leu Arg Ala Ile Ala Gln 120 125 130 gca gct gct gac ggg gtt att gat ggc cac aca atc caa gaa gcg cta 547 Ala Ala Ala Asp Gly Val Ile Asp Gly His Thr Ile Gln Glu Ala Leu 135 140 145 tcc att gct cgc tcc cta gtt gat cgc gca att aca gat cct gtg gag 595 Ser Ile Ala Arg Ser Leu Val Asp Arg Ala Ile Thr Asp Pro Val Glu 150 155 160 165 ggc act gtt gtc act gtg ttg cgt tct 622 Gly Thr Val Val Thr Val Leu Arg Ser 170 <210> 552 <211> 174 <212> PRT <213> Corynebacterium glutamicum <400> 552 Met Ser Ser Ser Glu Ser Ser Arg Ser Glu Gly Ser Gln Pro Ala Pro 1 5 10 15 Ser Val Gln Pro Glu Arg Arg Ala Asp Ser Thr Gly Ala Pro Ala Ala 20 25 30 Ala Ser Lys Glu Ala Ser Gln Gln Met Asp Ala Ala Gly Val Leu Glu 35 40 45 Trp Ala Arg Thr Ala Val Glu Gln Leu Ser Glu Arg Arg Ala Glu Ile 50 55 60 Asn Ala Leu Asn Val Phe Pro Val Pro Asp Ala Asp Thr Gly Ser Asn 65 70 75 80 Met Thr Tyr Thr Met Thr Ala Ala Leu Asp Glu Ala Leu Lys Leu Gly 85 90 95 Glu Leu Gly Asp Val Ala Arg Ile Thr Glu Ala Leu Ala Val Gly Ser 100 105 110 Val Arg Gly Ala Arg Gly Asn Ser Gly Val Val Leu Ser Gln Val Leu 115 120 125 Arg Ala Ile Ala Gln Ala Ala Ala Asp Gly Val Ile Asp Gly His Thr 130 135 140 Ile Gln Glu Ala Leu Ser Ile Ala Arg Ser Leu Val Asp Arg Ala Ile 145 150 155 160 Thr Asp Pro Val Glu Gly Thr Val Val Thr Val Leu Arg Ser 165 170 <210> 553 <211> 1107 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1084) <223> RXN02246 <400> 553 tgccgacgct ggcgtggatg ccttcgttgc aggttccgct gtgtacggcg ctgaggatcc 60 caacaaggcg atccaggagt tgcgagcact cgcgcagtaa atg gat gtt gcg cac 115 Met Asp Val Ala His 1 5 gcg tta gat ctg gcc cac cac gtg tca gat caa gtc cga ggc acc acc 163 Ala Leu Asp Leu Ala His His Val Ser Asp Gln Val Arg Gly Thr Thr 10 15 20 agc cct aat ccg cca gtc ggc gct gtc att ttg gac gcc gac ggc gag 211 Ser Pro Asn Pro Pro Val Gly Ala Val Ile Leu Asp Ala Asp Gly Glu 25 30 35 gtc gtt ggc gtt ggc gcc acg gca cct cct ggt ggc ccg cac gcc gaa 259 Val Val Gly Val Gly Ala Thr Ala Pro Pro Gly Gly Pro His Ala Glu 40 45 50 gtg gtg gcg ctt gca gct gcc gga gtg cgt gcc aac ggg ggc acg gcg 307 Val Val Ala Leu Ala Ala Ala Gly Val Arg Ala Asn Gly Gly Thr Ala 55 60 65 gtg gtc acc ctc gag ccg tgc aac cat tac ggc cgc acg ggt cca tgt 355 Val Val Thr Leu Glu Pro Cys Asn His Tyr Gly Arg Thr Gly Pro Cys 70 75 80 85 tcc aag gcg ctt ctc gac gcc ggg atc gca cac gtg ttt tac gcc aat 403 Ser Lys Ala Leu Leu Asp Ala Gly Ile Ala His Val Phe Tyr Ala Asn 90 95 100 gcg gat ccc ttc ccg tca gcc gct ggg ggc ggt gcc ttt ttg gcg gag 451 Ala Asp Pro Phe Pro Ser Ala Ala Gly Gly Gly Ala Phe Leu Ala Glu 105 110 115 gcg ggc gtc gat acg cat ttt tta gat gag cgg atc agg gca ctg gag 499 Ala Gly Val Asp Thr His Phe Leu Asp Glu Arg Ile Arg Ala Leu Glu 120 125 130 ccc tgg ctg gtt gcg acg cgt ctg ggc agg ccc cat gtc acg ttg aag 547 Pro Trp Leu Val Ala Thr Arg Leu Gly Arg Pro His Val Thr Leu Lys 135 140 145 ttt gcg tcc acc gtg gac ggt ttt gct ggt gcc acc gat ggc acc agc 595 Phe Ala Ser Thr Val Asp Gly Phe Ala Gly Ala Thr Asp Gly Thr Ser 150 155 160 165 cag tgg att acc ggg ccg gat gcg cgg gcg ttt gtg cac gaa gat cga 643 Gln Trp Ile Thr Gly Pro Asp Ala Arg Ala Phe Val His Glu Asp Arg 170 175 180 agt aaa aga gat gcg atc atc gtg ggt acc ggt act gcg ttg act gat 691 Ser Lys Arg Asp Ala Ile Ile Val Gly Thr Gly Thr Ala Leu Thr Asp 185 190 195 aat ccc tcc ttg acg gcg cgg acc gat acg ggt ctt tat gaa aat caa 739 Asn Pro Ser Leu Thr Ala Arg Thr Asp Thr Gly Leu Tyr Glu Asn Gln 200 205 210 ccc agg cgc gtt gtt att ggc tcc cgc gag gtt cca gca gat tcc aac 787 Pro Arg Arg Val Val Ile Gly Ser Arg Glu Val Pro Ala Asp Ser Asn 215 220 225 ttg gct cgc ttg gga tat gag cag tac gcg gga ata cca gag gct tta 835 Leu Ala Arg Leu Gly Tyr Glu Gln Tyr Ala Gly Ile Pro Glu Ala Leu 230 235 240 245 tca gcg ctg tgg gat aaa ggg tgc cga gac att tta atc gaa ggt ggc 883 Ser Ala Leu Trp Asp Lys Gly Cys Arg Asp Ile Leu Ile Glu Gly Gly 250 255 260 cca acg tta gct ggg gca gcg ctg cgc tta ggc att gtt gat cag gtg 931 Pro Thr Leu Ala Gly Ala Ala Leu Arg Leu Gly Ile Val Asp Gln Val 265 270 275 cag gcc tat gtt gcc ccc gct ttg ttg ggc gct gga cga tca gtg att 979 Gln Ala Tyr Val Ala Pro Ala Leu Leu Gly Ala Gly Arg Ser Val Ile 280 285 290 aac tgg cca caa gaa acc acg atg gat cag att atg cgt ttt gac acc 1027 Asn Trp Pro Gln Glu Thr Thr Met Asp Gln Ile Met Arg Phe Asp Thr 295 300 305 acg tcc gtg aga cag ttg ggt tca gat gta ttg ata gaa atg atg aga 1075 Thr Ser Val Arg Gln Leu Gly Ser Asp Val Leu Ile Glu Met Met Arg 310 315 320 325 aag gaa cac taaatgttca caggtattgt cga 1107 Lys Glu His <210> 554 <211> 328 <212> PRT <213> Corynebacterium glutamicum <400> 554 Met Asp Val Ala His Ala Leu Asp Leu Ala His His Val Ser Asp Gln 1 5 10 15 Val Arg Gly Thr Thr Ser Pro Asn Pro Pro Val Gly Ala Val Ile Leu 20 25 30 Asp Ala Asp Gly Glu Val Val Gly Val Gly Ala Thr Ala Pro Pro Gly 35 40 45 Gly Pro His Ala Glu Val Val Ala Leu Ala Ala Ala Gly Val Arg Ala 50 55 60 Asn Gly Gly Thr Ala Val Val Thr Leu Glu Pro Cys Asn His Tyr Gly 65 70 75 80 Arg Thr Gly Pro Cys Ser Lys Ala Leu Leu Asp Ala Gly Ile Ala His 85 90 95 Val Phe Tyr Ala Asn Ala Asp Pro Phe Pro Ser Ala Ala Gly Gly Gly 100 105 110 Ala Phe Leu Ala Glu Ala Gly Val Asp Thr His Phe Leu Asp Glu Arg 115 120 125 Ile Arg Ala Leu Glu Pro Trp Leu Val Ala Thr Arg Leu Gly Arg Pro 130 135 140 His Val Thr Leu Lys Phe Ala Ser Thr Val Asp Gly Phe Ala Gly Ala 145 150 155 160 Thr Asp Gly Thr Ser Gln Trp Ile Thr Gly Pro Asp Ala Arg Ala Phe 165 170 175 Val His Glu Asp Arg Ser Lys Arg Asp Ala Ile Ile Val Gly Thr Gly 180 185 190 Thr Ala Leu Thr Asp Asn Pro Ser Leu Thr Ala Arg Thr Asp Thr Gly 195 200 205 Leu Tyr Glu Asn Gln Pro Arg Arg Val Val Ile Gly Ser Arg Glu Val 210 215 220 Pro Ala Asp Ser Asn Leu Ala Arg Leu Gly Tyr Glu Gln Tyr Ala Gly 225 230 235 240 Ile Pro Glu Ala Leu Ser Ala Leu Trp Asp Lys Gly Cys Arg Asp Ile 245 250 255 Leu Ile Glu Gly Gly Pro Thr Leu Ala Gly Ala Ala Leu Arg Leu Gly 260 265 270 Ile Val Asp Gln Val Gln Ala Tyr Val Ala Pro Ala Leu Leu Gly Ala 275 280 285 Gly Arg Ser Val Ile Asn Trp Pro Gln Glu Thr Thr Met Asp Gln Ile 290 295 300 Met Arg Phe Asp Thr Thr Ser Val Arg Gln Leu Gly Ser Asp Val Leu 305 310 315 320 Ile Glu Met Met Arg Lys Glu His 325 <210> 555 <211> 1107 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1084) <223> FRXA02246 <400> 555 tgccgacgct ggcgtggatg ccttcgttgc aggttccgct gtgtacggcg ctgaggatcc 60 caacaaggcg atccaggagt tgcgagcact cgcgcagtaa atg gat gtt gcg cac 115 Met Asp Val Ala His 1 5 gcg tta gat ctg gcc cac cac gtg tca gat caa gtc cga ggc acc acc 163 Ala Leu Asp Leu Ala His His Val Ser Asp Gln Val Arg Gly Thr Thr 10 15 20 agc cct aat ccg cca gtc ggc gct gtc att ttg gac gcc gac ggc gag 211 Ser Pro Asn Pro Pro Val Gly Ala Val Ile Leu Asp Ala Asp Gly Glu 25 30 35 gtc gtt ggc gtt ggc gcc acg gca cct cct ggt ggc ccg cac gcc gaa 259 Val Val Gly Val Gly Ala Thr Ala Pro Pro Gly Gly Pro His Ala Glu 40 45 50 gtg gtg gcg ctt gca gct gcc gga gtg cgt gcc aac ggg ggc acg gcg 307 Val Val Ala Leu Ala Ala Ala Gly Val Arg Ala Asn Gly Gly Thr Ala 55 60 65 gtg gtc acc ctc gag ccg tgc aac cat tac ggc cgc acg ggt cca tgt 355 Val Val Thr Leu Glu Pro Cys Asn His Tyr Gly Arg Thr Gly Pro Cys 70 75 80 85 tcc aag gcg ctt ctc gac gcc ggg atc gca cac gtg ttt tac gcc aat 403 Ser Lys Ala Leu Leu Asp Ala Gly Ile Ala His Val Phe Tyr Ala Asn 90 95 100 gcg gat ccc ttc ccg tca gcc gct ggg ggc ggt gcc ttt ttg gcg gag 451 Ala Asp Pro Phe Pro Ser Ala Ala Gly Gly Gly Ala Phe Leu Ala Glu 105 110 115 gcg ggc gtc gat acg cat ttt tta gat gag cgg atc agg gca ctg gag 499 Ala Gly Val Asp Thr His Phe Leu Asp Glu Arg Ile Arg Ala Leu Glu 120 125 130 ccc tgg ctg gtt gcg acg cgt ctg ggc agg ccc cat gtc acg ttg aag 547 Pro Trp Leu Val Ala Thr Arg Leu Gly Arg Pro His Val Thr Leu Lys 135 140 145 ttt gcg tcc acc gtg gac ggt ttt gct ggt gcc acc gat ggc acc agc 595 Phe Ala Ser Thr Val Asp Gly Phe Ala Gly Ala Thr Asp Gly Thr Ser 150 155 160 165 cag tgg att acc ggg ccg gat gcg cgg gcg ttt gtg cac gaa gat cga 643 Gln Trp Ile Thr Gly Pro Asp Ala Arg Ala Phe Val His Glu Asp Arg 170 175 180 agt aaa aga gat gcg atc atc gtg ggt acc ggt act gcg ttg act gat 691 Ser Lys Arg Asp Ala Ile Ile Val Gly Thr Gly Thr Ala Leu Thr Asp 185 190 195 aat ccc tcc ttg acg gcg cgg acc gat acg ggt ctt tat gaa aat caa 739 Asn Pro Ser Leu Thr Ala Arg Thr Asp Thr Gly Leu Tyr Glu Asn Gln 200 205 210 ccc agg cgc gtt gtt att ggc tcc cgc gag gtt cca gca gat tcc aac 787 Pro Arg Arg Val Val Ile Gly Ser Arg Glu Val Pro Ala Asp Ser Asn 215 220 225 ttg gct cgc ttg gga tat gag cag tac gcg gga ata cca gag gct tta 835 Leu Ala Arg Leu Gly Tyr Glu Gln Tyr Ala Gly Ile Pro Glu Ala Leu 230 235 240 245 tca gcg ctg tgg gat aaa ggg tgc cga gac att tta atc gaa ggt ggc 883 Ser Ala Leu Trp Asp Lys Gly Cys Arg Asp Ile Leu Ile Glu Gly Gly 250 255 260 cca acg tta gct ggg gca gcg ctg cgc tta ggc att gtt gat cag gtg 931 Pro Thr Leu Ala Gly Ala Ala Leu Arg Leu Gly Ile Val Asp Gln Val 265 270 275 cag gcc tat gtt gcc ccc gct ttg ttg ggc gct gga cga tca gtg att 979 Gln Ala Tyr Val Ala Pro Ala Leu Leu Gly Ala Gly Arg Ser Val Ile 280 285 290 aac tgg cca caa gaa acc acg atg gat cag att atg cgt ttt gac acc 1027 Asn Trp Pro Gln Glu Thr Thr Met Asp Gln Ile Met Arg Phe Asp Thr 295 300 305 acg tcc gtg aga cag ttg ggt tca gat gta ttg ata gaa atg atg aga 1075 Thr Ser Val Arg Gln Leu Gly Ser Asp Val Leu Ile Glu Met Met Arg 310 315 320 325 aag gaa cac taaatgttca caggtattgt cga 1107 Lys Glu His <210> 556 <211> 328 <212> PRT <213> Corynebacterium glutamicum <400> 556 Met Asp Val Ala His Ala Leu Asp Leu Ala His His Val Ser Asp Gln 1 5 10 15 Val Arg Gly Thr Thr Ser Pro Asn Pro Pro Val Gly Ala Val Ile Leu 20 25 30 Asp Ala Asp Gly Glu Val Val Gly Val Gly Ala Thr Ala Pro Pro Gly 35 40 45 Gly Pro His Ala Glu Val Val Ala Leu Ala Ala Ala Gly Val Arg Ala 50 55 60 Asn Gly Gly Thr Ala Val Val Thr Leu Glu Pro Cys Asn His Tyr Gly 65 70 75 80 Arg Thr Gly Pro Cys Ser Lys Ala Leu Leu Asp Ala Gly Ile Ala His 85 90 95 Val Phe Tyr Ala Asn Ala Asp Pro Phe Pro Ser Ala Ala Gly Gly Gly 100 105 110 Ala Phe Leu Ala Glu Ala Gly Val Asp Thr His Phe Leu Asp Glu Arg 115 120 125 Ile Arg Ala Leu Glu Pro Trp Leu Val Ala Thr Arg Leu Gly Arg Pro 130 135 140 His Val Thr Leu Lys Phe Ala Ser Thr Val Asp Gly Phe Ala Gly Ala 145 150 155 160 Thr Asp Gly Thr Ser Gln Trp Ile Thr Gly Pro Asp Ala Arg Ala Phe 165 170 175 Val His Glu Asp Arg Ser Lys Arg Asp Ala Ile Ile Val Gly Thr Gly 180 185 190 Thr Ala Leu Thr Asp Asn Pro Ser Leu Thr Ala Arg Thr Asp Thr Gly 195 200 205 Leu Tyr Glu Asn Gln Pro Arg Arg Val Val Ile Gly Ser Arg Glu Val 210 215 220 Pro Ala Asp Ser Asn Leu Ala Arg Leu Gly Tyr Glu Gln Tyr Ala Gly 225 230 235 240 Ile Pro Glu Ala Leu Ser Ala Leu Trp Asp Lys Gly Cys Arg Asp Ile 245 250 255 Leu Ile Glu Gly Gly Pro Thr Leu Ala Gly Ala Ala Leu Arg Leu Gly 260 265 270 Ile Val Asp Gln Val Gln Ala Tyr Val Ala Pro Ala Leu Leu Gly Ala 275 280 285 Gly Arg Ser Val Ile Asn Trp Pro Gln Glu Thr Thr Met Asp Gln Ile 290 295 300 Met Arg Phe Asp Thr Thr Ser Val Arg Gln Leu Gly Ser Asp Val Leu 305 310 315 320 Ile Glu Met Met Arg Lys Glu His 325 <210> 557 <211> 756 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(733) <223> RXA02247 <400> 557 acaagaaacc acgatggatc agattatgcg ttttgacacc acgtccgtga gacagttggg 60 ttcagatgta ttgatagaaa tgatgagaaa ggaacactaa atg ttc aca ggt att 115 Met Phe Thr Gly Ile 1 5 gtc gag gag ctt ggc tcc gtt gca ggc gtg gaa cat ctg gga gat tcc 163 Val Glu Glu Leu Gly Ser Val Ala Gly Val Glu His Leu Gly Asp Ser 10 15 20 atc cgg atg cag att tcc gcg tcc acc gtt tta gag ggt gtg cat ttg 211 Ile Arg Met Gln Ile Ser Ala Ser Thr Val Leu Glu Gly Val His Leu 25 30 35 ggg gat tcc att tct gtc aat ggt gtg tgc ttg aca gtg gcg tcc ttt 259 Gly Asp Ser Ile Ser Val Asn Gly Val Cys Leu Thr Val Ala Ser Phe 40 45 50 ggc gag gga cat ttc act gca gac ctc atg cag gaa acc tta gat cgc 307 Gly Glu Gly His Phe Thr Ala Asp Leu Met Gln Glu Thr Leu Asp Arg 55 60 65 agc tcc ctg ggc gca tta tcc acc ggt agc aaa gtc aac ctt gag cgc 355 Ser Ser Leu Gly Ala Leu Ser Thr Gly Ser Lys Val Asn Leu Glu Arg 70 75 80 85 gcc atg gca gcc gat ggc cgt ctg ggt gga cac atc atg caa ggc cat 403 Ala Met Ala Ala Asp Gly Arg Leu Gly Gly His Ile Met Gln Gly His 90 95 100 gtt gat gcc acc acc tcg ctg atc aag cgc acc agc tca gag aac tgg 451 Val Asp Ala Thr Thr Ser Leu Ile Lys Arg Thr Ser Ser Glu Asn Trp 105 110 115 gat gtt ctg cgt ttt gag ctg cca gct gat ttg gct cgc tat gtg gtg 499 Asp Val Leu Arg Phe Glu Leu Pro Ala Asp Leu Ala Arg Tyr Val Val 120 125 130 gaa aaa ggc tcc atc gca ctc aat ggc aca tcc ttg act gta tcg tct 547 Glu Lys Gly Ser Ile Ala Leu Asn Gly Thr Ser Leu Thr Val Ser Ser 135 140 145 ttg ggt gat gat tgg ttt gag gtt tcc ctg att ccc acc acc ttg cgc 595 Leu Gly Asp Asp Trp Phe Glu Val Ser Leu Ile Pro Thr Thr Leu Arg 150 155 160 165 gac acc acc cac ggc gaa ctg gcg gta ggg gat atc gta aac att gag 643 Asp Thr Thr His Gly Glu Leu Ala Val Gly Asp Ile Val Asn Ile Glu 170 175 180 gtt gat gtg atc gct aag tac gtc gaa cgc atg atg acg cgc ggc gtg 691 Val Asp Val Ile Ala Lys Tyr Val Glu Arg Met Met Thr Arg Gly Val 185 190 195 gct gga aac act ccc aat gac tac acc gat ttc acg aga gac 733 Ala Gly Asn Thr Pro Asn Asp Tyr Thr Asp Phe Thr Arg Asp 200 205 210 taggttagac aacgtgagtg aac 756 <210> 558 <211> 211 <212> PRT <213> Corynebacterium glutamicum <400> 558 Met Phe Thr Gly Ile Val Glu Glu Leu Gly Ser Val Ala Gly Val Glu 1 5 10 15 His Leu Gly Asp Ser Ile Arg Met Gln Ile Ser Ala Ser Thr Val Leu 20 25 30 Glu Gly Val His Leu Gly Asp Ser Ile Ser Val Asn Gly Val Cys Leu 35 40 45 Thr Val Ala Ser Phe Gly Glu Gly His Phe Thr Ala Asp Leu Met Gln 50 55 60 Glu Thr Leu Asp Arg Ser Ser Leu Gly Ala Leu Ser Thr Gly Ser Lys 65 70 75 80 Val Asn Leu Glu Arg Ala Met Ala Ala Asp Gly Arg Leu Gly Gly His 85 90 95 Ile Met Gln Gly His Val Asp Ala Thr Thr Ser Leu Ile Lys Arg Thr 100 105 110 Ser Ser Glu Asn Trp Asp Val Leu Arg Phe Glu Leu Pro Ala Asp Leu 115 120 125 Ala Arg Tyr Val Val Glu Lys Gly Ser Ile Ala Leu Asn Gly Thr Ser 130 135 140 Leu Thr Val Ser Ser Leu Gly Asp Asp Trp Phe Glu Val Ser Leu Ile 145 150 155 160 Pro Thr Thr Leu Arg Asp Thr Thr His Gly Glu Leu Ala Val Gly Asp 165 170 175 Ile Val Asn Ile Glu Val Asp Val Ile Ala Lys Tyr Val Glu Arg Met 180 185 190 Met Thr Arg Gly Val Ala Gly Asn Thr Pro Asn Asp Tyr Thr Asp Phe 195 200 205 Thr Arg Asp 210 <210> 559 <211> 1389 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1366) <223> RXN02248 <400> 559 gatgtgatcg ctaagtacgt cgaacgcatg atgacgcgcg gcgtggctgg aaacactccc 60 aatgactaca ccgatttcac gagagactag gttagacaac gtg agt gaa cat gag 115 Val Ser Glu His Glu 1 5 cag gca cac agc caa tta gat tct gtt gaa gag gcc atc gct gac atc 163 Gln Ala His Ser Gln Leu Asp Ser Val Glu Glu Ala Ile Ala Asp Ile 10 15 20 gct gcg ggt aaa gcc gtc gtg gtg gta gat gat gaa gat cgt gaa aat 211 Ala Ala Gly Lys Ala Val Val Val Val Asp Asp Glu Asp Arg Glu Asn 25 30 35 gaa ggc gac atc atc ttt gcc gcc gaa tta gcc act cca gaa tta gtc 259 Glu Gly Asp Ile Ile Phe Ala Ala Glu Leu Ala Thr Pro Glu Leu Val 40 45 50 gct ttc atg gtg cgt tat tcc tcg gga tac atc tgt gcg cca tta acc 307 Ala Phe Met Val Arg Tyr Ser Ser Gly Tyr Ile Cys Ala Pro Leu Thr 55 60 65 gca aag gat gca gat cgt ctt gat ctg cct ccg atg acc gcg cac aat 355 Ala Lys Asp Ala Asp Arg Leu Asp Leu Pro Pro Met Thr Ala His Asn 70 75 80 85 cag gat gcc cgc ggc acc gct tac acc gtg acc gtt gat gcc aac acc 403 Gln Asp Ala Arg Gly Thr Ala Tyr Thr Val Thr Val Asp Ala Asn Thr 90 95 100 ggc acc aca ggc att tct gca aca gac cgc gcc cac act ttg cgc ttg 451 Gly Thr Thr Gly Ile Ser Ala Thr Asp Arg Ala His Thr Leu Arg Leu 105 110 115 ctt gct gat cca gaa gcc gac cgc acg gat ttc acc cgt ccc gga cac 499 Leu Ala Asp Pro Glu Ala Asp Arg Thr Asp Phe Thr Arg Pro Gly His 120 125 130 gtt gtg cca ctg cgt gct cgt gaa ggt ggc gtc ttg gtg cgc gct gga 547 Val Val Pro Leu Arg Ala Arg Glu Gly Gly Val Leu Val Arg Ala Gly 135 140 145 cac acc gaa gca gct gtc gat ttg gct cgc gct gca ggc ctg cgc cca 595 His Thr Glu Ala Ala Val Asp Leu Ala Arg Ala Ala Gly Leu Arg Pro 150 155 160 165 gca ggt gtt atc tgc gaa gtg gtc agt gaa gag gac ccc acc ggc atg 643 Ala Gly Val Ile Cys Glu Val Val Ser Glu Glu Asp Pro Thr Gly Met 170 175 180 gct cgg gtt cct gag ctg cgc cgc ttc tgc gat gag cac gat ctg aag 691 Ala Arg Val Pro Glu Leu Arg Arg Phe Cys Asp Glu His Asp Leu Lys 185 190 195 ctg atc tct att gag cag ctc att gag tgg cgt cgc aag aat gaa att 739 Leu Ile Ser Ile Glu Gln Leu Ile Glu Trp Arg Arg Lys Asn Glu Ile 200 205 210 ttg gtg gag cgc cag gtg gaa act gtg ctg cct acc gat ttc ggc acg 787 Leu Val Glu Arg Gln Val Glu Thr Val Leu Pro Thr Asp Phe Gly Thr 215 220 225 ttc aag gct gtt ggt tac cgt tcc atc atc gat ggc acc gag ctt gtt 835 Phe Lys Ala Val Gly Tyr Arg Ser Ile Ile Asp Gly Thr Glu Leu Val 230 235 240 245 gcc att gtt gcc ggc gac gtg gca tcc gac ggt ggc gaa aac gtc ctg 883 Ala Ile Val Ala Gly Asp Val Ala Ser Asp Gly Gly Glu Asn Val Leu 250 255 260 gtt cga gtc cac tct gag tgc ttg act ggt gat gtt ttt gga tcc cgg 931 Val Arg Val His Ser Glu Cys Leu Thr Gly Asp Val Phe Gly Ser Arg 265 270 275 cgc tgc gac tgt gga cag cag ctg cac gag tct ttg cgc ctg atc cag 979 Arg Cys Asp Cys Gly Gln Gln Leu His Glu Ser Leu Arg Leu Ile Gln 280 285 290 gaa gct ggt cgg gga gta gtg gtg tac atg cgt ggg cat gag gga cga 1027 Glu Ala Gly Arg Gly Val Val Val Tyr Met Arg Gly His Glu Gly Arg 295 300 305 ggc att ggt ctg ctc gcc aag cta cgc gcc tac caa ctc cag gat gaa 1075 Gly Ile Gly Leu Leu Ala Lys Leu Arg Ala Tyr Gln Leu Gln Asp Glu 310 315 320 325 ggt gcc gac acc gtc gat gcc aac ctc gca ctt ggt ctt cca gcc gat 1123 Gly Ala Asp Thr Val Asp Ala Asn Leu Ala Leu Gly Leu Pro Ala Asp 330 335 340 gcc cgc gaa ttt ggc acc agc gcc cag att ctc tac gac ttg ggt gtg 1171 Ala Arg Glu Phe Gly Thr Ser Ala Gln Ile Leu Tyr Asp Leu Gly Val 345 350 355 cgc tcg ctc aac ttg atc agc aac aac cca gcc aag aag gtg gga ctt 1219 Arg Ser Leu Asn Leu Ile Ser Asn Asn Pro Ala Lys Lys Val Gly Leu 360 365 370 gaa ggc cac ggc att tcc att gcc agc cga acc ccc atc cct gtt gct 1267 Glu Gly His Gly Ile Ser Ile Ala Ser Arg Thr Pro Ile Pro Val Ala 375 380 385 gtt cat gaa gac aat gtt cga tac ctg aaa acc aag cgt gac cgc atg 1315 Val His Glu Asp Asn Val Arg Tyr Leu Lys Thr Lys Arg Asp Arg Met 390 395 400 405 gga cat gac ctc cca gat gtc gca ctg tgg gaa caa gag cac cca gaa 1363 Gly His Asp Leu Pro Asp Val Ala Leu Trp Glu Gln Glu His Pro Glu 410 415 420 aac taaggagcac aacaatggct aaa 1389 Asn <210> 560 <211> 422 <212> PRT <213> Corynebacterium glutamicum <400> 560 Val Ser Glu His Glu Gln Ala His Ser Gln Leu Asp Ser Val Glu Glu 1 5 10 15 Ala Ile Ala Asp Ile Ala Ala Gly Lys Ala Val Val Val Val Asp Asp 20 25 30 Glu Asp Arg Glu Asn Glu Gly Asp Ile Ile Phe Ala Ala Glu Leu Ala 35 40 45 Thr Pro Glu Leu Val Ala Phe Met Val Arg Tyr Ser Ser Gly Tyr Ile 50 55 60 Cys Ala Pro Leu Thr Ala Lys Asp Ala Asp Arg Leu Asp Leu Pro Pro 65 70 75 80 Met Thr Ala His Asn Gln Asp Ala Arg Gly Thr Ala Tyr Thr Val Thr 85 90 95 Val Asp Ala Asn Thr Gly Thr Thr Gly Ile Ser Ala Thr Asp Arg Ala 100 105 110 His Thr Leu Arg Leu Leu Ala Asp Pro Glu Ala Asp Arg Thr Asp Phe 115 120 125 Thr Arg Pro Gly His Val Val Pro Leu Arg Ala Arg Glu Gly Gly Val 130 135 140 Leu Val Arg Ala Gly His Thr Glu Ala Ala Val Asp Leu Ala Arg Ala 145 150 155 160 Ala Gly Leu Arg Pro Ala Gly Val Ile Cys Glu Val Val Ser Glu Glu 165 170 175 Asp Pro Thr Gly Met Ala Arg Val Pro Glu Leu Arg Arg Phe Cys Asp 180 185 190 Glu His Asp Leu Lys Leu Ile Ser Ile Glu Gln Leu Ile Glu Trp Arg 195 200 205 Arg Lys Asn Glu Ile Leu Val Glu Arg Gln Val Glu Thr Val Leu Pro 210 215 220 Thr Asp Phe Gly Thr Phe Lys Ala Val Gly Tyr Arg Ser Ile Ile Asp 225 230 235 240 Gly Thr Glu Leu Val Ala Ile Val Ala Gly Asp Val Ala Ser Asp Gly 245 250 255 Gly Glu Asn Val Leu Val Arg Val His Ser Glu Cys Leu Thr Gly Asp 260 265 270 Val Phe Gly Ser Arg Arg Cys Asp Cys Gly Gln Gln Leu His Glu Ser 275 280 285 Leu Arg Leu Ile Gln Glu Ala Gly Arg Gly Val Val Val Tyr Met Arg 290 295 300 Gly His Glu Gly Arg Gly Ile Gly Leu Leu Ala Lys Leu Arg Ala Tyr 305 310 315 320 Gln Leu Gln Asp Glu Gly Ala Asp Thr Val Asp Ala Asn Leu Ala Leu 325 330 335 Gly Leu Pro Ala Asp Ala Arg Glu Phe Gly Thr Ser Ala Gln Ile Leu 340 345 350 Tyr Asp Leu Gly Val Arg Ser Leu Asn Leu Ile Ser Asn Asn Pro Ala 355 360 365 Lys Lys Val Gly Leu Glu Gly His Gly Ile Ser Ile Ala Ser Arg Thr 370 375 380 Pro Ile Pro Val Ala Val His Glu Asp Asn Val Arg Tyr Leu Lys Thr 385 390 395 400 Lys Arg Asp Arg Met Gly His Asp Leu Pro Asp Val Ala Leu Trp Glu 405 410 415 Gln Glu His Pro Glu Asn 420 <210> 561 <211> 1389 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1366) <223> FRXA02248 <400> 561 gatgtgatcg ctaagtacgt cgaacgcatg atgacgcgcg gcgtggctgg aaacactccc 60 aatgactaca ccgatttcac gagagactag gttagacaac gtg agt gaa cat gag 115 Val Ser Glu His Glu 1 5 cag gca cac agc caa tta gat tct gtt gaa gag gcc atc gct gac atc 163 Gln Ala His Ser Gln Leu Asp Ser Val Glu Glu Ala Ile Ala Asp Ile 10 15 20 gct gcg ggt aaa gcc gtc gtg gtg gta gat gat gaa gat cgt gaa aat 211 Ala Ala Gly Lys Ala Val Val Val Val Asp Asp Glu Asp Arg Glu Asn 25 30 35 gaa ggc gac atc atc ttt gcc gcc gaa tta gcc act cca gaa tta gtc 259 Glu Gly Asp Ile Ile Phe Ala Ala Glu Leu Ala Thr Pro Glu Leu Val 40 45 50 gct ttc atg gtg cgt tat tcc tcg gga tac atc tgt gcg cca tta acc 307 Ala Phe Met Val Arg Tyr Ser Ser Gly Tyr Ile Cys Ala Pro Leu Thr 55 60 65 gca aag gat gca gat cgt ctt gat ctg cct ccg atg acc gcg cac aat 355 Ala Lys Asp Ala Asp Arg Leu Asp Leu Pro Pro Met Thr Ala His Asn 70 75 80 85 cag gat gcc cgc ggc acc gct tac acc gtg acc gtt gat gcc aac acc 403 Gln Asp Ala Arg Gly Thr Ala Tyr Thr Val Thr Val Asp Ala Asn Thr 90 95 100 ggc acc aca ggc att tct gca aca gac cgc gcc cac act ttg cgc ttg 451 Gly Thr Thr Gly Ile Ser Ala Thr Asp Arg Ala His Thr Leu Arg Leu 105 110 115 ctt gct gat cca gaa gcc gac cgc acg gat ttc acc cgt ccc gga cac 499 Leu Ala Asp Pro Glu Ala Asp Arg Thr Asp Phe Thr Arg Pro Gly His 120 125 130 gtt gtg cca ctg cgt gct cgt gaa ggt ggc gtc ttg gtg cgc gct gga 547 Val Val Pro Leu Arg Ala Arg Glu Gly Gly Val Leu Val Arg Ala Gly 135 140 145 cac acc gaa gca gct gtc gat ttg gct cgc gct gca ggc ctg cgc cca 595 His Thr Glu Ala Ala Val Asp Leu Ala Arg Ala Ala Gly Leu Arg Pro 150 155 160 165 gca ggt gtt atc tgc gaa gtg gtc agt gaa gag gac ccc acc ggc atg 643 Ala Gly Val Ile Cys Glu Val Val Ser Glu Glu Asp Pro Thr Gly Met 170 175 180 gct cgg gtt cct gag ctg cgc cgc ttc tgc gat gag cac gat ctg aag 691 Ala Arg Val Pro Glu Leu Arg Arg Phe Cys Asp Glu His Asp Leu Lys 185 190 195 ctg atc tct att gag cag ctc att gag tgg cgt cgc aag aat gaa att 739 Leu Ile Ser Ile Glu Gln Leu Ile Glu Trp Arg Arg Lys Asn Glu Ile 200 205 210 ttg gtg gag cgc cag gtg gaa act gtg ctg cct acc gat ttc ggc acg 787 Leu Val Glu Arg Gln Val Glu Thr Val Leu Pro Thr Asp Phe Gly Thr 215 220 225 ttc aag gct gtt ggt tac cgt tcc atc atc gat ggc acc gag ctt gtt 835 Phe Lys Ala Val Gly Tyr Arg Ser Ile Ile Asp Gly Thr Glu Leu Val 230 235 240 245 gcc att gtt gcc ggc gac gtg gca tcc gac ggt ggc gaa aac gtc ctg 883 Ala Ile Val Ala Gly Asp Val Ala Ser Asp Gly Gly Glu Asn Val Leu 250 255 260 gtt cga gtc cac tct gag tgc ttg act ggt gat gtt ttt gga tcc cgg 931 Val Arg Val His Ser Glu Cys Leu Thr Gly Asp Val Phe Gly Ser Arg 265 270 275 cgc tgc gac tgt gga cag cag ctg cac gag tct ttg cgc ctg atc cag 979 Arg Cys Asp Cys Gly Gln Gln Leu His Glu Ser Leu Arg Leu Ile Gln 280 285 290 gaa gct ggt cgg gga gta gtg gtg tac atg cgt ggg cat gag gga cga 1027 Glu Ala Gly Arg Gly Val Val Val Tyr Met Arg Gly His Glu Gly Arg 295 300 305 ggc att ggt ctg ctc gcc aag cta cgc gcc tac caa ctc cag gat gaa 1075 Gly Ile Gly Leu Leu Ala Lys Leu Arg Ala Tyr Gln Leu Gln Asp Glu 310 315 320 325 ggt gcc gac acc gtc gat gcc aac ctc gca ctt ggt ctt cca gcc gat 1123 Gly Ala Asp Thr Val Asp Ala Asn Leu Ala Leu Gly Leu Pro Ala Asp 330 335 340 gcc cgc gaa ttt ggc acc agc gcc cag att ctc tac gac ttg ggt gtg 1171 Ala Arg Glu Phe Gly Thr Ser Ala Gln Ile Leu Tyr Asp Leu Gly Val 345 350 355 cgc tcg ctc aac ttg atc agc aac aac cca gcc aag aag gtg gga ctt 1219 Arg Ser Leu Asn Leu Ile Ser Asn Asn Pro Ala Lys Lys Val Gly Leu 360 365 370 gaa ggc cac ggc att tcc att gcc agc cga acc ccc atc cct gtt gct 1267 Glu Gly His Gly Ile Ser Ile Ala Ser Arg Thr Pro Ile Pro Val Ala 375 380 385 gtt cat gaa gac aat gtt cga tac ctg aaa acc aag cgt gac cgc atg 1315 Val His Glu Asp Asn Val Arg Tyr Leu Lys Thr Lys Arg Asp Arg Met 390 395 400 405 gga cat gac ctc cca gat gtc gca ctg tgg gaa caa gag cac cca gaa 1363 Gly His Asp Leu Pro Asp Val Ala Leu Trp Glu Gln Glu His Pro Glu 410 415 420 aac taaggagcac aacaatggct aaa 1389 Asn <210> 562 <211> 422 <212> PRT <213> Corynebacterium glutamicum <400> 562 Val Ser Glu His Glu Gln Ala His Ser Gln Leu Asp Ser Val Glu Glu 1 5 10 15 Ala Ile Ala Asp Ile Ala Ala Gly Lys Ala Val Val Val Val Asp Asp 20 25 30 Glu Asp Arg Glu Asn Glu Gly Asp Ile Ile Phe Ala Ala Glu Leu Ala 35 40 45 Thr Pro Glu Leu Val Ala Phe Met Val Arg Tyr Ser Ser Gly Tyr Ile 50 55 60 Cys Ala Pro Leu Thr Ala Lys Asp Ala Asp Arg Leu Asp Leu Pro Pro 65 70 75 80 Met Thr Ala His Asn Gln Asp Ala Arg Gly Thr Ala Tyr Thr Val Thr 85 90 95 Val Asp Ala Asn Thr Gly Thr Thr Gly Ile Ser Ala Thr Asp Arg Ala 100 105 110 His Thr Leu Arg Leu Leu Ala Asp Pro Glu Ala Asp Arg Thr Asp Phe 115 120 125 Thr Arg Pro Gly His Val Val Pro Leu Arg Ala Arg Glu Gly Gly Val 130 135 140 Leu Val Arg Ala Gly His Thr Glu Ala Ala Val Asp Leu Ala Arg Ala 145 150 155 160 Ala Gly Leu Arg Pro Ala Gly Val Ile Cys Glu Val Val Ser Glu Glu 165 170 175 Asp Pro Thr Gly Met Ala Arg Val Pro Glu Leu Arg Arg Phe Cys Asp 180 185 190 Glu His Asp Leu Lys Leu Ile Ser Ile Glu Gln Leu Ile Glu Trp Arg 195 200 205 Arg Lys Asn Glu Ile Leu Val Glu Arg Gln Val Glu Thr Val Leu Pro 210 215 220 Thr Asp Phe Gly Thr Phe Lys Ala Val Gly Tyr Arg Ser Ile Ile Asp 225 230 235 240 Gly Thr Glu Leu Val Ala Ile Val Ala Gly Asp Val Ala Ser Asp Gly 245 250 255 Gly Glu Asn Val Leu Val Arg Val His Ser Glu Cys Leu Thr Gly Asp 260 265 270 Val Phe Gly Ser Arg Arg Cys Asp Cys Gly Gln Gln Leu His Glu Ser 275 280 285 Leu Arg Leu Ile Gln Glu Ala Gly Arg Gly Val Val Val Tyr Met Arg 290 295 300 Gly His Glu Gly Arg Gly Ile Gly Leu Leu Ala Lys Leu Arg Ala Tyr 305 310 315 320 Gln Leu Gln Asp Glu Gly Ala Asp Thr Val Asp Ala Asn Leu Ala Leu 325 330 335 Gly Leu Pro Ala Asp Ala Arg Glu Phe Gly Thr Ser Ala Gln Ile Leu 340 345 350 Tyr Asp Leu Gly Val Arg Ser Leu Asn Leu Ile Ser Asn Asn Pro Ala 355 360 365 Lys Lys Val Gly Leu Glu Gly His Gly Ile Ser Ile Ala Ser Arg Thr 370 375 380 Pro Ile Pro Val Ala Val His Glu Asp Asn Val Arg Tyr Leu Lys Thr 385 390 395 400 Lys Arg Asp Arg Met Gly His Asp Leu Pro Asp Val Ala Leu Trp Glu 405 410 415 Gln Glu His Pro Glu Asn 420 <210> 563 <211> 600 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(577) <223> RXN02249 <400> 563 atgttcgata cctgaaaacc aagcgtgacc gcatgggaca tgacctccca gatgtcgcac 60 tgtgggaaca agagcaccca gaaaactaag gagcacaaca atg gct aaa gaa gga 115 Met Ala Lys Glu Gly 1 5 ttg ccg gca gtc gaa ctc ccc gac gcc agc gga tta aaa gtc gcc gta 163 Leu Pro Ala Val Glu Leu Pro Asp Ala Ser Gly Leu Lys Val Ala Val 10 15 20 gtc acc gca cgg tgg aac gca gaa atc tgc gac cgc ctg cac aag cac 211 Val Thr Ala Arg Trp Asn Ala Glu Ile Cys Asp Arg Leu His Lys His 25 30 35 gca gta gat gcg gga cgt gca gca gga gca acg gtg agc gaa tac cgc 259 Ala Val Asp Ala Gly Arg Ala Ala Gly Ala Thr Val Ser Glu Tyr Arg 40 45 50 gtc atc ggc gcc ctg gaa ctt cca gtc gta gtg caa gaa ctg gca cgc 307 Val Ile Gly Ala Leu Glu Leu Pro Val Val Val Gln Glu Leu Ala Arg 55 60 65 acc cat gac gca gta gtt gcc ttg ggc tgt gtc gtt cgt ggc ggc acc 355 Thr His Asp Ala Val Val Ala Leu Gly Cys Val Val Arg Gly Gly Thr 70 75 80 85 cca cac ttt gat tac gtg tgc gac tct gtc acc gaa ggc ctc acc cgc 403 Pro His Phe Asp Tyr Val Cys Asp Ser Val Thr Glu Gly Leu Thr Arg 90 95 100 att gct ctt gat act tcc acc cca atc ggc aac ggt gtg ttg act acc 451 Ile Ala Leu Asp Thr Ser Thr Pro Ile Gly Asn Gly Val Leu Thr Thr 105 110 115 aac acc gaa gag caa gcc gtg gaa cgc tcc ggt gga gaa ggc tct gta 499 Asn Thr Glu Glu Gln Ala Val Glu Arg Ser Gly Gly Glu Gly Ser Val 120 125 130 gag gac aaa ggc gca gag gca atg gtc gct gca ctc gat act gcc ctc 547 Glu Asp Lys Gly Ala Glu Ala Met Val Ala Ala Leu Asp Thr Ala Leu 135 140 145 gtg ctt tct caa att cgt gca act gag ggt tagactgttc tttaaaaggt 597 Val Leu Ser Gln Ile Arg Ala Thr Glu Gly 150 155 ttg 600 <210> 564 <211> 159 <212> PRT <213> Corynebacterium glutamicum <400> 564 Met Ala Lys Glu Gly Leu Pro Ala Val Glu Leu Pro Asp Ala Ser Gly 1 5 10 15 Leu Lys Val Ala Val Val Thr Ala Arg Trp Asn Ala Glu Ile Cys Asp 20 25 30 Arg Leu His Lys His Ala Val Asp Ala Gly Arg Ala Ala Gly Ala Thr 35 40 45 Val Ser Glu Tyr Arg Val Ile Gly Ala Leu Glu Leu Pro Val Val Val 50 55 60 Gln Glu Leu Ala Arg Thr His Asp Ala Val Val Ala Leu Gly Cys Val 65 70 75 80 Val Arg Gly Gly Thr Pro His Phe Asp Tyr Val Cys Asp Ser Val Thr 85 90 95 Glu Gly Leu Thr Arg Ile Ala Leu Asp Thr Ser Thr Pro Ile Gly Asn 100 105 110 Gly Val Leu Thr Thr Asn Thr Glu Glu Gln Ala Val Glu Arg Ser Gly 115 120 125 Gly Glu Gly Ser Val Glu Asp Lys Gly Ala Glu Ala Met Val Ala Ala 130 135 140 Leu Asp Thr Ala Leu Val Leu Ser Gln Ile Arg Ala Thr Glu Gly 145 150 155 <210> 565 <211> 600 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(577) <223> FRXA02249 <400> 565 atgttcgata cctgaaaacc aagcgtgacc gcatgggaca tgacctccca gatgtcgcac 60 tgtgggaaca agagcaccca gaaaactaag gagcacaaca atg gct aaa gaa gga 115 Met Ala Lys Glu Gly 1 5 ttg ccg gca gtc gaa ctc ccc gac gcc agc gga tta aaa gtc gcc gta 163 Leu Pro Ala Val Glu Leu Pro Asp Ala Ser Gly Leu Lys Val Ala Val 10 15 20 gtc acc gca cgg tgg aac gca gaa atc tgc gac cgc ctg cac aag cac 211 Val Thr Ala Arg Trp Asn Ala Glu Ile Cys Asp Arg Leu His Lys His 25 30 35 gca gta gat gcg gga cgt gca gca gga gca acg gtg agc gaa tac cgc 259 Ala Val Asp Ala Gly Arg Ala Ala Gly Ala Thr Val Ser Glu Tyr Arg 40 45 50 gtc atc ggc gcc ctg gaa ctt cca gtc gta gtg caa gaa ctg gca cgc 307 Val Ile Gly Ala Leu Glu Leu Pro Val Val Val Gln Glu Leu Ala Arg 55 60 65 acc cat gac gca gta gtt gcc ttg ggc tgt gtc gtt cgt ggc ggc acc 355 Thr His Asp Ala Val Val Ala Leu Gly Cys Val Val Arg Gly Gly Thr 70 75 80 85 cca cac ttt gat tac gtg tgc gac tct gtc acc gaa ggc ctc acc cgc 403 Pro His Phe Asp Tyr Val Cys Asp Ser Val Thr Glu Gly Leu Thr Arg 90 95 100 att gct ctt gat act tcc acc cca atc ggc aac ggt gtg ttg act acc 451 Ile Ala Leu Asp Thr Ser Thr Pro Ile Gly Asn Gly Val Leu Thr Thr 105 110 115 aac acc gaa gag caa gcc gtg gaa cgc tcc ggt gga gaa ggc tct gta 499 Asn Thr Glu Glu Gln Ala Val Glu Arg Ser Gly Gly Glu Gly Ser Val 120 125 130 gag gac aaa ggc gca gag gca atg gtc gct gca ctc gat act gcc ctc 547 Glu Asp Lys Gly Ala Glu Ala Met Val Ala Ala Leu Asp Thr Ala Leu 135 140 145 gtg ctt tct caa att cgt gca act gag ggt tagactgttc tttaaaaggt 597 Val Leu Ser Gln Ile Arg Ala Thr Glu Gly 150 155 ttg 600 <210> 566 <211> 159 <212> PRT <213> Corynebacterium glutamicum <400> 566 Met Ala Lys Glu Gly Leu Pro Ala Val Glu Leu Pro Asp Ala Ser Gly 1 5 10 15 Leu Lys Val Ala Val Val Thr Ala Arg Trp Asn Ala Glu Ile Cys Asp 20 25 30 Arg Leu His Lys His Ala Val Asp Ala Gly Arg Ala Ala Gly Ala Thr 35 40 45 Val Ser Glu Tyr Arg Val Ile Gly Ala Leu Glu Leu Pro Val Val Val 50 55 60 Gln Glu Leu Ala Arg Thr His Asp Ala Val Val Ala Leu Gly Cys Val 65 70 75 80 Val Arg Gly Gly Thr Pro His Phe Asp Tyr Val Cys Asp Ser Val Thr 85 90 95 Glu Gly Leu Thr Arg Ile Ala Leu Asp Thr Ser Thr Pro Ile Gly Asn 100 105 110 Gly Val Leu Thr Thr Asn Thr Glu Glu Gln Ala Val Glu Arg Ser Gly 115 120 125 Gly Glu Gly Ser Val Glu Asp Lys Gly Ala Glu Ala Met Val Ala Ala 130 135 140 Leu Asp Thr Ala Leu Val Leu Ser Gln Ile Arg Ala Thr Glu Gly 145 150 155 <210> 567 <211> 702 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(679) <223> RXA02250 <400> 567 caactgaggg ttagactgtt ctttaaaagg tttgacgcct cggtttaatg cctagcagga 60 tgcgcgccac cgctaattag ttctaaggat ttgtgaaatc gtg aca acc aac gcc 115 Val Thr Thr Asn Ala 1 5 ccc gac gga gca acg aac aac atc aac aac gca cat tcg ggc gct gtc 163 Pro Asp Gly Ala Thr Asn Asn Ile Asn Asn Ala His Ser Gly Ala Val 10 15 20 ggg aag cca aag gta cag ctc agc gat gcg gaa att cag gaa tac acc 211 Gly Lys Pro Lys Val Gln Leu Ser Asp Ala Glu Ile Gln Glu Tyr Thr 25 30 35 gca gct ttc gct ggc acc acc aca acc aag cca tgg gag ctg gag gtg 259 Ala Ala Phe Ala Gly Thr Thr Thr Thr Lys Pro Trp Glu Leu Glu Val 40 45 50 acc aca aag ttt ctg aaa aag atc gcg tgg gta gcc gtg gtt gtc atc 307 Thr Thr Lys Phe Leu Lys Lys Ile Ala Trp Val Ala Val Val Val Ile 55 60 65 atg gcc gtt cac atc ttc atg ggt gcc gtg gtg gac gtc gat ttc acc 355 Met Ala Val His Ile Phe Met Gly Ala Val Val Asp Val Asp Phe Thr 70 75 80 85 ggt gca gcg gtc acc ttt gtt gac act ctg gca ttc cca gcg ttg ggc 403 Gly Ala Ala Val Thr Phe Val Asp Thr Leu Ala Phe Pro Ala Leu Gly 90 95 100 atc atc ttc tcc gtt ctt gtg ttc ttg gga ctg act cgc cct cgc gtg 451 Ile Ile Phe Ser Val Leu Val Phe Leu Gly Leu Thr Arg Pro Arg Val 105 110 115 cgt gcc aac gaa gac ggc gtt gag gtg cgt aac ttc atc gga act cgt 499 Arg Ala Asn Glu Asp Gly Val Glu Val Arg Asn Phe Ile Gly Thr Arg 120 125 130 ttc tac cca tgg gtt gtc atc tac ggc atg tct ttc ccc aag ggc agc 547 Phe Tyr Pro Trp Val Val Ile Tyr Gly Met Ser Phe Pro Lys Gly Ser 135 140 145 agc gtg gca cgt ttg gag ctt cca gac ttt gaa ttc gtt ccc atg tgg 595 Ser Val Ala Arg Leu Glu Leu Pro Asp Phe Glu Phe Val Pro Met Trp 150 155 160 165 gct ttc cag tcc cgc gat gga gaa gat gtg gtg cgc gcg gtt gcg acc 643 Ala Phe Gln Ser Arg Asp Gly Glu Asp Val Val Arg Ala Val Ala Thr 170 175 180 ttc cgc gac ctc gaa aac aag tac atg cca gag gac taattaagct 689 Phe Arg Asp Leu Glu Asn Lys Tyr Met Pro Glu Asp 185 190 gtggctgatc caa 702 <210> 568 <211> 193 <212> PRT <213> Corynebacterium glutamicum <400> 568 Val Thr Thr Asn Ala Pro Asp Gly Ala Thr Asn Asn Ile Asn Asn Ala 1 5 10 15 His Ser Gly Ala Val Gly Lys Pro Lys Val Gln Leu Ser Asp Ala Glu 20 25 30 Ile Gln Glu Tyr Thr Ala Ala Phe Ala Gly Thr Thr Thr Thr Lys Pro 35 40 45 Trp Glu Leu Glu Val Thr Thr Lys Phe Leu Lys Lys Ile Ala Trp Val 50 55 60 Ala Val Val Val Ile Met Ala Val His Ile Phe Met Gly Ala Val Val 65 70 75 80 Asp Val Asp Phe Thr Gly Ala Ala Val Thr Phe Val Asp Thr Leu Ala 85 90 95 Phe Pro Ala Leu Gly Ile Ile Phe Ser Val Leu Val Phe Leu Gly Leu 100 105 110 Thr Arg Pro Arg Val Arg Ala Asn Glu Asp Gly Val Glu Val Arg Asn 115 120 125 Phe Ile Gly Thr Arg Phe Tyr Pro Trp Val Val Ile Tyr Gly Met Ser 130 135 140 Phe Pro Lys Gly Ser Ser Val Ala Arg Leu Glu Leu Pro Asp Phe Glu 145 150 155 160 Phe Val Pro Met Trp Ala Phe Gln Ser Arg Asp Gly Glu Asp Val Val 165 170 175 Arg Ala Val Ala Thr Phe Arg Asp Leu Glu Asn Lys Tyr Met Pro Glu 180 185 190 Asp <210> 569 <211> 1146 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1123) <223> RXA01489 <400> 569 gtcatgggat gtcattccgg cgggcttgtc gacgatcacg agtccaggtt taggggcagg 60 agcattcatg tctgttgagt ctatgccgta gtctaaaaca gtg gat att tgg agt 115 Val Asp Ile Trp Ser 1 5 gga cta gac agc gtt ccg gct gat ctt caa gga tca gta gtc acc att 163 Gly Leu Asp Ser Val Pro Ala Asp Leu Gln Gly Ser Val Val Thr Ile 10 15 20 ggt gtg ttt gat ggg ctc cac cgg ggg cat caa agt tta atc ggc gag 211 Gly Val Phe Asp Gly Leu His Arg Gly His Gln Ser Leu Ile Gly Glu 25 30 35 gcc aag aag cag gcc gag gag ctg ggt gtg cct tgt gtc atg gtg acc 259 Ala Lys Lys Gln Ala Glu Glu Leu Gly Val Pro Cys Val Met Val Thr 40 45 50 ttt gac ccg cat ccg atc gct gtg ttt ttg cca ggt aaa gag cca acc 307 Phe Asp Pro His Pro Ile Ala Val Phe Leu Pro Gly Lys Glu Pro Thr 55 60 65 cgt ttg gct cct ttg gat tat cgc ctt aat ttg gct gcg gaa tgt ggc 355 Arg Leu Ala Pro Leu Asp Tyr Arg Leu Asn Leu Ala Ala Glu Cys Gly 70 75 80 85 gtc gat gct gcg ttg gtt att gat ttc act aaa gaa ctc gca ggt ctg 403 Val Asp Ala Ala Leu Val Ile Asp Phe Thr Lys Glu Leu Ala Gly Leu 90 95 100 agc gct gaa gag tat ttc aca acc atg atc gtg gat acg ctg cat gcg 451 Ser Ala Glu Glu Tyr Phe Thr Thr Met Ile Val Asp Thr Leu His Ala 105 110 115 cgt tca gtt gtg gtg ggg gag aac ttc acc ttc ggt gtc aat ggc gct 499 Arg Ser Val Val Val Gly Glu Asn Phe Thr Phe Gly Val Asn Gly Ala 120 125 130 ggc act gag tcc acg atg cgg gaa ttg gga caa aag ttt ggc gtg aat 547 Gly Thr Glu Ser Thr Met Arg Glu Leu Gly Gln Lys Phe Gly Val Asn 135 140 145 gtc acg att gct ccg ctg ctg cat gat gat gac cag cgt att tgc tcc 595 Val Thr Ile Ala Pro Leu Leu His Asp Asp Asp Gln Arg Ile Cys Ser 150 155 160 165 acc ttg gtg cgc gat tac ttg gat cag ggc gag gtt gag cgc gcg aac 643 Thr Leu Val Arg Asp Tyr Leu Asp Gln Gly Glu Val Glu Arg Ala Asn 170 175 180 tgg gcg ctt ggt cga cgc tat gcc gtg cgc ggc gaa gtt gtc cgt ggt 691 Trp Ala Leu Gly Arg Arg Tyr Ala Val Arg Gly Glu Val Val Arg Gly 185 190 195 gct ggc cgt ggc ggc aaa gaa ttg ggc tat ccc acc gcg aat ctc tac 739 Ala Gly Arg Gly Gly Lys Glu Leu Gly Tyr Pro Thr Ala Asn Leu Tyr 200 205 210 ctg ccg acc tct gtg gcg ctg ccc gcc gat ggc gtg tat gca ggc tgg 787 Leu Pro Thr Ser Val Ala Leu Pro Ala Asp Gly Val Tyr Ala Gly Trp 215 220 225 ttc acc atc acc gat gac cgc gaa atc gac aag gaa atc tcc cgc gat 835 Phe Thr Ile Thr Asp Asp Arg Glu Ile Asp Lys Glu Ile Ser Arg Asp 230 235 240 245 atc gac ggc acc atg gtt cca ggc gtg cgt tac caa act gcc att tcc 883 Ile Asp Gly Thr Met Val Pro Gly Val Arg Tyr Gln Thr Ala Ile Ser 250 255 260 gtg ggc acc aat ccc acc ttc ggc gat gag cga cgc agc gtc gag gca 931 Val Gly Thr Asn Pro Thr Phe Gly Asp Glu Arg Arg Ser Val Glu Ala 265 270 275 ttc atc ctc gac cag gaa gcc gac ctg tac ggt cac cat gtc atg gtg 979 Phe Ile Leu Asp Gln Glu Ala Asp Leu Tyr Gly His His Val Met Val 280 285 290 gaa ttc gtg gga cac ttg cgc gac atg gtc aaa ttc aac ggc gtc gac 1027 Glu Phe Val Gly His Leu Arg Asp Met Val Lys Phe Asn Gly Val Asp 295 300 305 gag cta cta gac gcc atg gcc cga gat gtc acc aac gcc cgc gac atc 1075 Glu Leu Leu Asp Ala Met Ala Arg Asp Val Thr Asn Ala Arg Asp Ile 310 315 320 325 ctt gcc aaa gac aaa ttg ctt ctc gac gcc gac acc cag ccc agc gct 1123 Leu Ala Lys Asp Lys Leu Leu Leu Asp Ala Asp Thr Gln Pro Ser Ala 330 335 340 taaggccggt caccggccat caa 1146 <210> 570 <211> 341 <212> PRT <213> Corynebacterium glutamicum <400> 570 Val Asp Ile Trp Ser Gly Leu Asp Ser Val Pro Ala Asp Leu Gln Gly 1 5 10 15 Ser Val Val Thr Ile Gly Val Phe Asp Gly Leu His Arg Gly His Gln 20 25 30 Ser Leu Ile Gly Glu Ala Lys Lys Gln Ala Glu Glu Leu Gly Val Pro 35 40 45 Cys Val Met Val Thr Phe Asp Pro His Pro Ile Ala Val Phe Leu Pro 50 55 60 Gly Lys Glu Pro Thr Arg Leu Ala Pro Leu Asp Tyr Arg Leu Asn Leu 65 70 75 80 Ala Ala Glu Cys Gly Val Asp Ala Ala Leu Val Ile Asp Phe Thr Lys 85 90 95 Glu Leu Ala Gly Leu Ser Ala Glu Glu Tyr Phe Thr Thr Met Ile Val 100 105 110 Asp Thr Leu His Ala Arg Ser Val Val Val Gly Glu Asn Phe Thr Phe 115 120 125 Gly Val Asn Gly Ala Gly Thr Glu Ser Thr Met Arg Glu Leu Gly Gln 130 135 140 Lys Phe Gly Val Asn Val Thr Ile Ala Pro Leu Leu His Asp Asp Asp 145 150 155 160 Gln Arg Ile Cys Ser Thr Leu Val Arg Asp Tyr Leu Asp Gln Gly Glu 165 170 175 Val Glu Arg Ala Asn Trp Ala Leu Gly Arg Arg Tyr Ala Val Arg Gly 180 185 190 Glu Val Val Arg Gly Ala Gly Arg Gly Gly Lys Glu Leu Gly Tyr Pro 195 200 205 Thr Ala Asn Leu Tyr Leu Pro Thr Ser Val Ala Leu Pro Ala Asp Gly 210 215 220 Val Tyr Ala Gly Trp Phe Thr Ile Thr Asp Asp Arg Glu Ile Asp Lys 225 230 235 240 Glu Ile Ser Arg Asp Ile Asp Gly Thr Met Val Pro Gly Val Arg Tyr 245 250 255 Gln Thr Ala Ile Ser Val Gly Thr Asn Pro Thr Phe Gly Asp Glu Arg 260 265 270 Arg Ser Val Glu Ala Phe Ile Leu Asp Gln Glu Ala Asp Leu Tyr Gly 275 280 285 His His Val Met Val Glu Phe Val Gly His Leu Arg Asp Met Val Lys 290 295 300 Phe Asn Gly Val Asp Glu Leu Leu Asp Ala Met Ala Arg Asp Val Thr 305 310 315 320 Asn Ala Arg Asp Ile Leu Ala Lys Asp Lys Leu Leu Leu Asp Ala Asp 325 330 335 Thr Gln Pro Ser Ala 340 <210> 571 <211> 1197 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1174) <223> RXA02135 <400> 571 cgtgtcgcag cgatttgcga gagggttgtc ttcgtggttg ctggtctgcc actagagttg 60 aaaacgtttt aagaaaacag tcggtttgaa ggagttgtta atg gtt cca gca gag 115 Met Val Pro Ala Glu 1 5 ctt ttt gcg cgt gtg gaa ttt ccg gat cat aaa atc ctg gct cag acg 163 Leu Phe Ala Arg Val Glu Phe Pro Asp His Lys Ile Leu Ala Gln Thr 10 15 20 aag gat ttc cat gac tcc ctc acc aag cca ccc gga tct ttg ggc aag 211 Lys Asp Phe His Asp Ser Leu Thr Lys Pro Pro Gly Ser Leu Gly Lys 25 30 35 ttg gag cag atc ggc tgt ttc att tcc gca tgc cag ggc cag att ccg 259 Leu Glu Gln Ile Gly Cys Phe Ile Ser Ala Cys Gln Gly Gln Ile Pro 40 45 50 cca cgt cca ctc aac aac tca aag atc gtt gtt ttc gct ggc gat cac 307 Pro Arg Pro Leu Asn Asn Ser Lys Ile Val Val Phe Ala Gly Asp His 55 60 65 ggc gtt gca act aaa ggc gtg tcc gcg tac cca tcc tca gta agc ttg 355 Gly Val Ala Thr Lys Gly Val Ser Ala Tyr Pro Ser Ser Val Ser Leu 70 75 80 85 cag atg gct gaa aac att aca aac ggt ggc gcc gcc atc aac gtg att 403 Gln Met Ala Glu Asn Ile Thr Asn Gly Gly Ala Ala Ile Asn Val Ile 90 95 100 gca cgc acc acc ggc acg tcc gtc cga ctt att gat acc tcc ctc gac 451 Ala Arg Thr Thr Gly Thr Ser Val Arg Leu Ile Asp Thr Ser Leu Asp 105 110 115 cac gaa gca tgg ggc gac gag cgc gta tct agg tcc tgc gga tcc atc 499 His Glu Ala Trp Gly Asp Glu Arg Val Ser Arg Ser Cys Gly Ser Ile 120 125 130 gat gtt gaa gac gcc atg acc caa gaa cag gtc gaa cgc gca ctg aag 547 Asp Val Glu Asp Ala Met Thr Gln Glu Gln Val Glu Arg Ala Leu Lys 135 140 145 atc ggt aag cgc att gcg gat caa gaa gtg gac gca ggc gcc gac att 595 Ile Gly Lys Arg Ile Ala Asp Gln Glu Val Asp Ala Gly Ala Asp Ile 150 155 160 165 tta atc ccc ggc gat tta gga att ggc aac acc acc acc gcc gct gcc 643 Leu Ile Pro Gly Asp Leu Gly Ile Gly Asn Thr Thr Thr Ala Ala Ala 170 175 180 ctc gtt gga acg ttc acc ctc gca gag cct gtt gtt gtc gta ggc cgc 691 Leu Val Gly Thr Phe Thr Leu Ala Glu Pro Val Val Val Val Gly Arg 185 190 195 ggc acc gga atc gac gat gaa gcc tgg aaa ctc aaa gtc tcc gcg atc 739 Gly Thr Gly Ile Asp Asp Glu Ala Trp Lys Leu Lys Val Ser Ala Ile 200 205 210 cgc gac gcc atg ttc cgc gcc cgc gac ctg cgc caa gac ccc atc gcc 787 Arg Asp Ala Met Phe Arg Ala Arg Asp Leu Arg Gln Asp Pro Ile Ala 215 220 225 atc gcc cgg aaa atc tct tcc cca gac ctt gca gcc atg gca gca ttc 835 Ile Ala Arg Lys Ile Ser Ser Pro Asp Leu Ala Ala Met Ala Ala Phe 230 235 240 245 att gcc caa gca gca gtt cga cgc acc ccc gtg ctt ctc gac ggc gtt 883 Ile Ala Gln Ala Ala Val Arg Arg Thr Pro Val Leu Leu Asp Gly Val 250 255 260 gta gtc acc gcc gca gcc ctc cta gcc aac aaa ctg gcc cca ggt gcc 931 Val Val Thr Ala Ala Ala Leu Leu Ala Asn Lys Leu Ala Pro Gly Ala 265 270 275 agg cgt tgg ttc atc gca gga cac cgc tcc acc gaa cca gcg cat tcc 979 Arg Arg Trp Phe Ile Ala Gly His Arg Ser Thr Glu Pro Ala His Ser 280 285 290 gta gct cta aac gca ctg gcc ctt gat ccc atc ctg gaa ctt gga atg 1027 Val Ala Leu Asn Ala Leu Ala Leu Asp Pro Ile Leu Glu Leu Gly Met 295 300 305 tcc ctt ggc gaa ggc tcc ggc gca gcc acc gca ctc ccc ctg gtc aag 1075 Ser Leu Gly Glu Gly Ser Gly Ala Ala Thr Ala Leu Pro Leu Val Lys 310 315 320 325 att gcc gtt gac ctg atg aac gac atg tcg aca ttt tct tcc gcc ggc 1123 Ile Ala Val Asp Leu Met Asn Asp Met Ser Thr Phe Ser Ser Ala Gly 330 335 340 gtc gat gga ccc cta aac gcc tct tcc gaa gcg ccc gag caa aac acg 1171 Val Asp Gly Pro Leu Asn Ala Ser Ser Glu Ala Pro Glu Gln Asn Thr 345 350 355 gag taactttcta agcgatgtcc ggc 1197 Glu <210> 572 <211> 358 <212> PRT <213> Corynebacterium glutamicum <400> 572 Met Val Pro Ala Glu Leu Phe Ala Arg Val Glu Phe Pro Asp His Lys 1 5 10 15 Ile Leu Ala Gln Thr Lys Asp Phe His Asp Ser Leu Thr Lys Pro Pro 20 25 30 Gly Ser Leu Gly Lys Leu Glu Gln Ile Gly Cys Phe Ile Ser Ala Cys 35 40 45 Gln Gly Gln Ile Pro Pro Arg Pro Leu Asn Asn Ser Lys Ile Val Val 50 55 60 Phe Ala Gly Asp His Gly Val Ala Thr Lys Gly Val Ser Ala Tyr Pro 65 70 75 80 Ser Ser Val Ser Leu Gln Met Ala Glu Asn Ile Thr Asn Gly Gly Ala 85 90 95 Ala Ile Asn Val Ile Ala Arg Thr Thr Gly Thr Ser Val Arg Leu Ile 100 105 110 Asp Thr Ser Leu Asp His Glu Ala Trp Gly Asp Glu Arg Val Ser Arg 115 120 125 Ser Cys Gly Ser Ile Asp Val Glu Asp Ala Met Thr Gln Glu Gln Val 130 135 140 Glu Arg Ala Leu Lys Ile Gly Lys Arg Ile Ala Asp Gln Glu Val Asp 145 150 155 160 Ala Gly Ala Asp Ile Leu Ile Pro Gly Asp Leu Gly Ile Gly Asn Thr 165 170 175 Thr Thr Ala Ala Ala Leu Val Gly Thr Phe Thr Leu Ala Glu Pro Val 180 185 190 Val Val Val Gly Arg Gly Thr Gly Ile Asp Asp Glu Ala Trp Lys Leu 195 200 205 Lys Val Ser Ala Ile Arg Asp Ala Met Phe Arg Ala Arg Asp Leu Arg 210 215 220 Gln Asp Pro Ile Ala Ile Ala Arg Lys Ile Ser Ser Pro Asp Leu Ala 225 230 235 240 Ala Met Ala Ala Phe Ile Ala Gln Ala Ala Val Arg Arg Thr Pro Val 245 250 255 Leu Leu Asp Gly Val Val Val Thr Ala Ala Ala Leu Leu Ala Asn Lys 260 265 270 Leu Ala Pro Gly Ala Arg Arg Trp Phe Ile Ala Gly His Arg Ser Thr 275 280 285 Glu Pro Ala His Ser Val Ala Leu Asn Ala Leu Ala Leu Asp Pro Ile 290 295 300 Leu Glu Leu Gly Met Ser Leu Gly Glu Gly Ser Gly Ala Ala Thr Ala 305 310 315 320 Leu Pro Leu Val Lys Ile Ala Val Asp Leu Met Asn Asp Met Ser Thr 325 330 335 Phe Ser Ser Ala Gly Val Asp Gly Pro Leu Asn Ala Ser Ser Glu Ala 340 345 350 Pro Glu Gln Asn Thr Glu 355 <210> 573 <211> 1146 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1123) <223> RXA01489 <400> 573 gtcatgggat gtcattccgg cgggcttgtc gacgatcacg agtccaggtt taggggcagg 60 agcattcatg tctgttgagt ctatgccgta gtctaaaaca gtg gat att tgg agt 115 Val Asp Ile Trp Ser 1 5 gga cta gac agc gtt ccg gct gat ctt caa gga tca gta gtc acc att 163 Gly Leu Asp Ser Val Pro Ala Asp Leu Gln Gly Ser Val Val Thr Ile 10 15 20 ggt gtg ttt gat ggg ctc cac cgg ggg cat caa agt tta atc ggc gag 211 Gly Val Phe Asp Gly Leu His Arg Gly His Gln Ser Leu Ile Gly Glu 25 30 35 gcc aag aag cag gcc gag gag ctg ggt gtg cct tgt gtc atg gtg acc 259 Ala Lys Lys Gln Ala Glu Glu Leu Gly Val Pro Cys Val Met Val Thr 40 45 50 ttt gac ccg cat ccg atc gct gtg ttt ttg cca ggt aaa gag cca acc 307 Phe Asp Pro His Pro Ile Ala Val Phe Leu Pro Gly Lys Glu Pro Thr 55 60 65 cgt ttg gct cct ttg gat tat cgc ctt aat ttg gct gcg gaa tgt ggc 355 Arg Leu Ala Pro Leu Asp Tyr Arg Leu Asn Leu Ala Ala Glu Cys Gly 70 75 80 85 gtc gat gct gcg ttg gtt att gat ttc act aaa gaa ctc gca ggt ctg 403 Val Asp Ala Ala Leu Val Ile Asp Phe Thr Lys Glu Leu Ala Gly Leu 90 95 100 agc gct gaa gag tat ttc aca acc atg atc gtg gat acg ctg cat gcg 451 Ser Ala Glu Glu Tyr Phe Thr Thr Met Ile Val Asp Thr Leu His Ala 105 110 115 cgt tca gtt gtg gtg ggg gag aac ttc acc ttc ggt gtc aat ggc gct 499 Arg Ser Val Val Val Gly Glu Asn Phe Thr Phe Gly Val Asn Gly Ala 120 125 130 ggc act gag tcc acg atg cgg gaa ttg gga caa aag ttt ggc gtg aat 547 Gly Thr Glu Ser Thr Met Arg Glu Leu Gly Gln Lys Phe Gly Val Asn 135 140 145 gtc acg att gct ccg ctg ctg cat gat gat gac cag cgt att tgc tcc 595 Val Thr Ile Ala Pro Leu Leu His Asp Asp Asp Gln Arg Ile Cys Ser 150 155 160 165 acc ttg gtg cgc gat tac ttg gat cag ggc gag gtt gag cgc gcg aac 643 Thr Leu Val Arg Asp Tyr Leu Asp Gln Gly Glu Val Glu Arg Ala Asn 170 175 180 tgg gcg ctt ggt cga cgc tat gcc gtg cgc ggc gaa gtt gtc cgt ggt 691 Trp Ala Leu Gly Arg Arg Tyr Ala Val Arg Gly Glu Val Val Arg Gly 185 190 195 gct ggc cgt ggc ggc aaa gaa ttg ggc tat ccc acc gcg aat ctc tac 739 Ala Gly Arg Gly Gly Lys Glu Leu Gly Tyr Pro Thr Ala Asn Leu Tyr 200 205 210 ctg ccg acc tct gtg gcg ctg ccc gcc gat ggc gtg tat gca ggc tgg 787 Leu Pro Thr Ser Val Ala Leu Pro Ala Asp Gly Val Tyr Ala Gly Trp 215 220 225 ttc acc atc acc gat gac cgc gaa atc gac aag gaa atc tcc cgc gat 835 Phe Thr Ile Thr Asp Asp Arg Glu Ile Asp Lys Glu Ile Ser Arg Asp 230 235 240 245 atc gac ggc acc atg gtt cca ggc gtg cgt tac caa act gcc att tcc 883 Ile Asp Gly Thr Met Val Pro Gly Val Arg Tyr Gln Thr Ala Ile Ser 250 255 260 gtg ggc acc aat ccc acc ttc ggc gat gag cga cgc agc gtc gag gca 931 Val Gly Thr Asn Pro Thr Phe Gly Asp Glu Arg Arg Ser Val Glu Ala 265 270 275 ttc atc ctc gac cag gaa gcc gac ctg tac ggt cac cat gtc atg gtg 979 Phe Ile Leu Asp Gln Glu Ala Asp Leu Tyr Gly His His Val Met Val 280 285 290 gaa ttc gtg gga cac ttg cgc gac atg gtc aaa ttc aac ggc gtc gac 1027 Glu Phe Val Gly His Leu Arg Asp Met Val Lys Phe Asn Gly Val Asp 295 300 305 gag cta cta gac gcc atg gcc cga gat gtc acc aac gcc cgc gac atc 1075 Glu Leu Leu Asp Ala Met Ala Arg Asp Val Thr Asn Ala Arg Asp Ile 310 315 320 325 ctt gcc aaa gac aaa ttg ctt ctc gac gcc gac acc cag ccc agc gct 1123 Leu Ala Lys Asp Lys Leu Leu Leu Asp Ala Asp Thr Gln Pro Ser Ala 330 335 340 taaggccggt caccggccat caa 1146 <210> 574 <211> 341 <212> PRT <213> Corynebacterium glutamicum <400> 574 Val Asp Ile Trp Ser Gly Leu Asp Ser Val Pro Ala Asp Leu Gln Gly 1 5 10 15 Ser Val Val Thr Ile Gly Val Phe Asp Gly Leu His Arg Gly His Gln 20 25 30 Ser Leu Ile Gly Glu Ala Lys Lys Gln Ala Glu Glu Leu Gly Val Pro 35 40 45 Cys Val Met Val Thr Phe Asp Pro His Pro Ile Ala Val Phe Leu Pro 50 55 60 Gly Lys Glu Pro Thr Arg Leu Ala Pro Leu Asp Tyr Arg Leu Asn Leu 65 70 75 80 Ala Ala Glu Cys Gly Val Asp Ala Ala Leu Val Ile Asp Phe Thr Lys 85 90 95 Glu Leu Ala Gly Leu Ser Ala Glu Glu Tyr Phe Thr Thr Met Ile Val 100 105 110 Asp Thr Leu His Ala Arg Ser Val Val Val Gly Glu Asn Phe Thr Phe 115 120 125 Gly Val Asn Gly Ala Gly Thr Glu Ser Thr Met Arg Glu Leu Gly Gln 130 135 140 Lys Phe Gly Val Asn Val Thr Ile Ala Pro Leu Leu His Asp Asp Asp 145 150 155 160 Gln Arg Ile Cys Ser Thr Leu Val Arg Asp Tyr Leu Asp Gln Gly Glu 165 170 175 Val Glu Arg Ala Asn Trp Ala Leu Gly Arg Arg Tyr Ala Val Arg Gly 180 185 190 Glu Val Val Arg Gly Ala Gly Arg Gly Gly Lys Glu Leu Gly Tyr Pro 195 200 205 Thr Ala Asn Leu Tyr Leu Pro Thr Ser Val Ala Leu Pro Ala Asp Gly 210 215 220 Val Tyr Ala Gly Trp Phe Thr Ile Thr Asp Asp Arg Glu Ile Asp Lys 225 230 235 240 Glu Ile Ser Arg Asp Ile Asp Gly Thr Met Val Pro Gly Val Arg Tyr 245 250 255 Gln Thr Ala Ile Ser Val Gly Thr Asn Pro Thr Phe Gly Asp Glu Arg 260 265 270 Arg Ser Val Glu Ala Phe Ile Leu Asp Gln Glu Ala Asp Leu Tyr Gly 275 280 285 His His Val Met Val Glu Phe Val Gly His Leu Arg Asp Met Val Lys 290 295 300 Phe Asn Gly Val Asp Glu Leu Leu Asp Ala Met Ala Arg Asp Val Thr 305 310 315 320 Asn Ala Arg Asp Ile Leu Ala Lys Asp Lys Leu Leu Leu Asp Ala Asp 325 330 335 Thr Gln Pro Ser Ala 340 <210> 575 <211> 805 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (87)..(782) <223> RXN01712 <400> 575 gccggcttag gctcctccga ccagaacccc actggcacct ttggataaca ccattccgtg 60 taaacaagct ggcctagact tgaaac atg gtc gat atc ttg gaa ctc atc ggt 113 Met Val Asp Ile Leu Glu Leu Ile Gly 1 5 ccc cta cct ttt gtg tct acg cca gag tta agg gca att gtc gtg act 161 Pro Leu Pro Phe Val Ser Thr Pro Glu Leu Arg Ala Ile Val Val Thr 10 15 20 25 gcc att aat ggt tcc acc act att aat ggc acg tct ggt cag ctt gga 209 Ala Ile Asn Gly Ser Thr Thr Ile Asn Gly Thr Ser Gly Gln Leu Gly 30 35 40 aat tcc acg gat acg gaa ctt ctg ttg gcg ctt cgc agg tgg tcg gac 257 Asn Ser Thr Asp Thr Glu Leu Leu Leu Ala Leu Arg Arg Trp Ser Asp 45 50 55 gtg gtg ttg gtt ggg tcg agc acg gtg aag gct gaa aat tat ggt ggc 305 Val Val Leu Val Gly Ser Ser Thr Val Lys Ala Glu Asn Tyr Gly Gly 60 65 70 gtg gag gtt tcg cct gaa atc cag aag caa cgc cag gag ttg ggt cag 353 Val Glu Val Ser Pro Glu Ile Gln Lys Gln Arg Gln Glu Leu Gly Gln 75 80 85 gaa gcg att ccg ccg att gcg gtg atg tca ggg tcg ttg aat ttt gat 401 Glu Ala Ile Pro Pro Ile Ala Val Met Ser Gly Ser Leu Asn Phe Asp 90 95 100 105 gtg gat act cgc ttt ttc ctt gag gcc gaa gtg ccg ccg atc atc atc 449 Val Asp Thr Arg Phe Phe Leu Glu Ala Glu Val Pro Pro Ile Ile Ile 110 115 120 acg gat aat tcc gat caa gca aag cag cag cgg ctt gtg gat gct ggg 497 Thr Asp Asn Ser Asp Gln Ala Lys Gln Gln Arg Leu Val Asp Ala Gly 125 130 135 gct cag gtt att gag gtg gag acg ttg acg gcg gag gtt ggc gtc gaa 545 Ala Gln Val Ile Glu Val Glu Thr Leu Thr Ala Glu Val Gly Val Glu 140 145 150 aag ctt agg tct ttg ggt tac gcc cgc att gat tgt gag ggc ggt gca 593 Lys Leu Arg Ser Leu Gly Tyr Ala Arg Ile Asp Cys Glu Gly Gly Ala 155 160 165 acg ttg tat ggg cag atg ttg gcc gcc gat ctt gtt gat gtg tgg cat 641 Thr Leu Tyr Gly Gln Met Leu Ala Ala Asp Leu Val Asp Val Trp His 170 175 180 185 cac acg att gat ccg acg ttg tcg ggc agc gtg gag cgc ccc acg gtg 689 His Thr Ile Asp Pro Thr Leu Ser Gly Ser Val Glu Arg Pro Thr Val 190 195 200 aag ggc ggc gat gat gcg ccg cgc cga ttc gcg ttg gag cac gtc ttt 737 Lys Gly Gly Asp Asp Ala Pro Arg Arg Phe Ala Leu Glu His Val Phe 205 210 215 gtc gat gat gac agc acc cta ttc ttg cgg tat aag cgc gcc aag 782 Val Asp Asp Asp Ser Thr Leu Phe Leu Arg Tyr Lys Arg Ala Lys 220 225 230 tgagtgttgg actctccgga tct 805 <210> 576 <211> 232 <212> PRT <213> Corynebacterium glutamicum <400> 576 Met Val Asp Ile Leu Glu Leu Ile Gly Pro Leu Pro Phe Val Ser Thr 1 5 10 15 Pro Glu Leu Arg Ala Ile Val Val Thr Ala Ile Asn Gly Ser Thr Thr 20 25 30 Ile Asn Gly Thr Ser Gly Gln Leu Gly Asn Ser Thr Asp Thr Glu Leu 35 40 45 Leu Leu Ala Leu Arg Arg Trp Ser Asp Val Val Leu Val Gly Ser Ser 50 55 60 Thr Val Lys Ala Glu Asn Tyr Gly Gly Val Glu Val Ser Pro Glu Ile 65 70 75 80 Gln Lys Gln Arg Gln Glu Leu Gly Gln Glu Ala Ile Pro Pro Ile Ala 85 90 95 Val Met Ser Gly Ser Leu Asn Phe Asp Val Asp Thr Arg Phe Phe Leu 100 105 110 Glu Ala Glu Val Pro Pro Ile Ile Ile Thr Asp Asn Ser Asp Gln Ala 115 120 125 Lys Gln Gln Arg Leu Val Asp Ala Gly Ala Gln Val Ile Glu Val Glu 130 135 140 Thr Leu Thr Ala Glu Val Gly Val Glu Lys Leu Arg Ser Leu Gly Tyr 145 150 155 160 Ala Arg Ile Asp Cys Glu Gly Gly Ala Thr Leu Tyr Gly Gln Met Leu 165 170 175 Ala Ala Asp Leu Val Asp Val Trp His His Thr Ile Asp Pro Thr Leu 180 185 190 Ser Gly Ser Val Glu Arg Pro Thr Val Lys Gly Gly Asp Asp Ala Pro 195 200 205 Arg Arg Phe Ala Leu Glu His Val Phe Val Asp Asp Asp Ser Thr Leu 210 215 220 Phe Leu Arg Tyr Lys Arg Ala Lys 225 230 <210> 577 <211> 578 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (55)..(555) <223> FRXA01712 <400> 577 cttctgttgg cgcttcgcag gtggtcggac gtggtgttgg ttgggtcgag cacg gtg 57 Val 1 aag gct gaa aat tat ggt ggc gtg gag gtt tcg cct gaa atc cag aag 105 Lys Ala Glu Asn Tyr Gly Gly Val Glu Val Ser Pro Glu Ile Gln Lys 5 10 15 caa cgc cag gag ttg ggt cag gaa gcg att ccg ccg att gcg gtg atg 153 Gln Arg Gln Glu Leu Gly Gln Glu Ala Ile Pro Pro Ile Ala Val Met 20 25 30 tca ggg tcg ttg aat ttt gat gtg gat act cgc ttt ttc ctt gag gcc 201 Ser Gly Ser Leu Asn Phe Asp Val Asp Thr Arg Phe Phe Leu Glu Ala 35 40 45 gaa gtg ccg ccg atc atc atc acg gat aat tcc gat caa gca aag cag 249 Glu Val Pro Pro Ile Ile Ile Thr Asp Asn Ser Asp Gln Ala Lys Gln 50 55 60 65 cag cgg ctt gtg gat gct ggg gct cag gtt att gag gtg gag acg ttg 297 Gln Arg Leu Val Asp Ala Gly Ala Gln Val Ile Glu Val Glu Thr Leu 70 75 80 acg gcg gag gtt ggc gtc gaa aag ctt agg tct ttg ggt tac gcc cgc 345 Thr Ala Glu Val Gly Val Glu Lys Leu Arg Ser Leu Gly Tyr Ala Arg 85 90 95 att gat tgt gag ggc ggt gca acg ttg tat ggg cag atg ttg gcc gcc 393 Ile Asp Cys Glu Gly Gly Ala Thr Leu Tyr Gly Gln Met Leu Ala Ala 100 105 110 gat ctt gtt gat gtg tgg cat cac acg att gat ccg acg ttg tcg ggc 441 Asp Leu Val Asp Val Trp His His Thr Ile Asp Pro Thr Leu Ser Gly 115 120 125 agc gtg gag cgc ccc acg gtg aag ggc ggc gat gat gcg ccg cgc cga 489 Ser Val Glu Arg Pro Thr Val Lys Gly Gly Asp Asp Ala Pro Arg Arg 130 135 140 145 ttc gcg ttg gag cac gtc ttt gtc gat gat gac agc acc cta ttc ttg 537 Phe Ala Leu Glu His Val Phe Val Asp Asp Asp Ser Thr Leu Phe Leu 150 155 160 cgg tat aag cgc gcc aag tgagtgttgg actctccgga tct 578 Arg Tyr Lys Arg Ala Lys 165 <210> 578 <211> 167 <212> PRT <213> Corynebacterium glutamicum <400> 578 Val Lys Ala Glu Asn Tyr Gly Gly Val Glu Val Ser Pro Glu Ile Gln 1 5 10 15 Lys Gln Arg Gln Glu Leu Gly Gln Glu Ala Ile Pro Pro Ile Ala Val 20 25 30 Met Ser Gly Ser Leu Asn Phe Asp Val Asp Thr Arg Phe Phe Leu Glu 35 40 45 Ala Glu Val Pro Pro Ile Ile Ile Thr Asp Asn Ser Asp Gln Ala Lys 50 55 60 Gln Gln Arg Leu Val Asp Ala Gly Ala Gln Val Ile Glu Val Glu Thr 65 70 75 80 Leu Thr Ala Glu Val Gly Val Glu Lys Leu Arg Ser Leu Gly Tyr Ala 85 90 95 Arg Ile Asp Cys Glu Gly Gly Ala Thr Leu Tyr Gly Gln Met Leu Ala 100 105 110 Ala Asp Leu Val Asp Val Trp His His Thr Ile Asp Pro Thr Leu Ser 115 120 125 Gly Ser Val Glu Arg Pro Thr Val Lys Gly Gly Asp Asp Ala Pro Arg 130 135 140 Arg Phe Ala Leu Glu His Val Phe Val Asp Asp Asp Ser Thr Leu Phe 145 150 155 160 Leu Arg Tyr Lys Arg Ala Lys 165 <210> 579 <211> 831 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(808) <223> RXN02384 <400> 579 ctgatgaggc ggatatccgc aacatcgaca gcattgatga actcccacct ttgccagctg 60 aatacgagcc tggctacgag gacgattaag aggtagtcct gtg act cgt cgc ctg 115 Val Thr Arg Arg Leu 1 5 att ctg ctc cga cac ggg cag act gaa tac aac gcc acg tcc cga atg 163 Ile Leu Leu Arg His Gly Gln Thr Glu Tyr Asn Ala Thr Ser Arg Met 10 15 20 cag gga caa ttg gac aca gag ctg tct gac ctg ggc ttt caa cag gcg 211 Gln Gly Gln Leu Asp Thr Glu Leu Ser Asp Leu Gly Phe Gln Gln Ala 25 30 35 gcc agc gca gcc tca gtg ctg gtt caa aaa aac atc acc cat gtg ttc 259 Ala Ser Ala Ala Ser Val Leu Val Gln Lys Asn Ile Thr His Val Phe 40 45 50 agc tcg gat ctt tcc cgc gcc ttc aac acc gca agc gcg gtt gcg gcg 307 Ser Ser Asp Leu Ser Arg Ala Phe Asn Thr Ala Ser Ala Val Ala Ala 55 60 65 ctg att gac gcg gag gtg cgc gtc gat aag cgt ctt cgg gaa acg cat 355 Leu Ile Asp Ala Glu Val Arg Val Asp Lys Arg Leu Arg Glu Thr His 70 75 80 85 ttg ggt gag tgg cag gcc aaa acc cac act gag gtg gat tcc gaa tat 403 Leu Gly Glu Trp Gln Ala Lys Thr His Thr Glu Val Asp Ser Glu Tyr 90 95 100 cca ggt gcg cgc gct caa tgg cgc cac gat ccg cag tgg gca cca ccc 451 Pro Gly Ala Arg Ala Gln Trp Arg His Asp Pro Gln Trp Ala Pro Pro 105 110 115 ggc ggc gaa tcg cgc gtg gat gtt gcg cgc cgg gca cgc caa gtt gtc 499 Gly Gly Glu Ser Arg Val Asp Val Ala Arg Arg Ala Arg Gln Val Val 120 125 130 gac gag ttg atg gtg tcg ctt gat gat tgg gat gaa ggc acc gtg ctc 547 Asp Glu Leu Met Val Ser Leu Asp Asp Trp Asp Glu Gly Thr Val Leu 135 140 145 atc gtg gct cac ggt ggc acg att aat gcg ctg acc tcg aat ctt ttg 595 Ile Val Ala His Gly Gly Thr Ile Asn Ala Leu Thr Ser Asn Leu Leu 150 155 160 165 gac ctg gcg tat gat cag tac ccc atg ttc tct gga ctt gga aat acc 643 Asp Leu Ala Tyr Asp Gln Tyr Pro Met Phe Ser Gly Leu Gly Asn Thr 170 175 180 tgt tgg gca caa ttg acc gcc cga cct cgc tat tat gca ggt agt gag 691 Cys Trp Ala Gln Leu Thr Ala Arg Pro Arg Tyr Tyr Ala Gly Ser Glu 185 190 195 aac cca gaa gat gac ctc aag att tct tcg gcg gtt tcc aac agc cct 739 Asn Pro Glu Asp Asp Leu Lys Ile Ser Ser Ala Val Ser Asn Ser Pro 200 205 210 cat ttt gag ggc aac aat gtg gaa aac gcc cag tgg tat ctt gac ggc 787 His Phe Glu Gly Asn Asn Val Glu Asn Ala Gln Trp Tyr Leu Asp Gly 215 220 225 tgg aac atg ggt gtt acg cag taaagaagat ggcaataaaa atg 831 Trp Asn Met Gly Val Thr Gln 230 235 <210> 580 <211> 236 <212> PRT <213> Corynebacterium glutamicum <400> 580 Val Thr Arg Arg Leu Ile Leu Leu Arg His Gly Gln Thr Glu Tyr Asn 1 5 10 15 Ala Thr Ser Arg Met Gln Gly Gln Leu Asp Thr Glu Leu Ser Asp Leu 20 25 30 Gly Phe Gln Gln Ala Ala Ser Ala Ala Ser Val Leu Val Gln Lys Asn 35 40 45 Ile Thr His Val Phe Ser Ser Asp Leu Ser Arg Ala Phe Asn Thr Ala 50 55 60 Ser Ala Val Ala Ala Leu Ile Asp Ala Glu Val Arg Val Asp Lys Arg 65 70 75 80 Leu Arg Glu Thr His Leu Gly Glu Trp Gln Ala Lys Thr His Thr Glu 85 90 95 Val Asp Ser Glu Tyr Pro Gly Ala Arg Ala Gln Trp Arg His Asp Pro 100 105 110 Gln Trp Ala Pro Pro Gly Gly Glu Ser Arg Val Asp Val Ala Arg Arg 115 120 125 Ala Arg Gln Val Val Asp Glu Leu Met Val Ser Leu Asp Asp Trp Asp 130 135 140 Glu Gly Thr Val Leu Ile Val Ala His Gly Gly Thr Ile Asn Ala Leu 145 150 155 160 Thr Ser Asn Leu Leu Asp Leu Ala Tyr Asp Gln Tyr Pro Met Phe Ser 165 170 175 Gly Leu Gly Asn Thr Cys Trp Ala Gln Leu Thr Ala Arg Pro Arg Tyr 180 185 190 Tyr Ala Gly Ser Glu Asn Pro Glu Asp Asp Leu Lys Ile Ser Ser Ala 195 200 205 Val Ser Asn Ser Pro His Phe Glu Gly Asn Asn Val Glu Asn Ala Gln 210 215 220 Trp Tyr Leu Asp Gly Trp Asn Met Gly Val Thr Gln 225 230 235 <210> 581 <211> 453 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(430) <223> RXN01560 <400> 581 atgggagcaa ggctcattta gctacttcga cgtggaagcg cacatcgttg agttgattcc 60 tgcatcagta agcgatgcgt tttaggcaca tctgcgatcc gtg ggc gtg tcc tac 115 Val Gly Val Ser Tyr 1 5 atc atc gcc ggc gat gag cag ctg gat atg gca gaa gcc gtt cgc aaa 163 Ile Ile Ala Gly Asp Glu Gln Leu Asp Met Ala Glu Ala Val Arg Lys 10 15 20 att ggg gag acc ttt aaa act gag gaa att atc ctt ggt ggc gga gga 211 Ile Gly Glu Thr Phe Lys Thr Glu Glu Ile Ile Leu Gly Gly Gly Gly 25 30 35 acc ctg aac tgg tcc atg ctc cgc gac ggt ttg tgc gac gag gtt agc 259 Thr Leu Asn Trp Ser Met Leu Arg Asp Gly Leu Cys Asp Glu Val Ser 40 45 50 atc gtg atg atg cca atc gcc gat ggt gaa aag cac acc cac tct ttg 307 Ile Val Met Met Pro Ile Ala Asp Gly Glu Lys His Thr His Ser Leu 55 60 65 ttc gaa gcc gat gaa aaa tac tca gca ccg ttg ccg atc ggt ttt tca 355 Phe Glu Ala Asp Glu Lys Tyr Ser Ala Pro Leu Pro Ile Gly Phe Ser 70 75 80 85 ctc gcc agc gtt gaa cca cta gaa gat gga agc gtt tgg atg cgt tac 403 Leu Ala Ser Val Glu Pro Leu Glu Asp Gly Ser Val Trp Met Arg Tyr 90 95 100 ggg gtc aat ggc cca gtg gac gcg aac taggtagcaa atactcgctc 450 Gly Val Asn Gly Pro Val Asp Ala Asn 105 110 ttt 453 <210> 582 <211> 110 <212> PRT <213> Corynebacterium glutamicum <400> 582 Val Gly Val Ser Tyr Ile Ile Ala Gly Asp Glu Gln Leu Asp Met Ala 1 5 10 15 Glu Ala Val Arg Lys Ile Gly Glu Thr Phe Lys Thr Glu Glu Ile Ile 20 25 30 Leu Gly Gly Gly Gly Thr Leu Asn Trp Ser Met Leu Arg Asp Gly Leu 35 40 45 Cys Asp Glu Val Ser Ile Val Met Met Pro Ile Ala Asp Gly Glu Lys 50 55 60 His Thr His Ser Leu Phe Glu Ala Asp Glu Lys Tyr Ser Ala Pro Leu 65 70 75 80 Pro Ile Gly Phe Ser Leu Ala Ser Val Glu Pro Leu Glu Asp Gly Ser 85 90 95 Val Trp Met Arg Tyr Gly Val Asn Gly Pro Val Asp Ala Asn 100 105 110 <210> 583 <211> 1137 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1114) <223> RXN00667 <400> 583 ggcatcagtg tttgaaggga aaagcaggtc aaacaaggtg cggctgattt gagcgatcac 60 agcaccgaga tctgtgctga agaattcaat gattgggttg atg att gcg ttg aag 115 Met Ile Ala Leu Lys 1 5 tcc atg tct aac agg gta gta caa aag cca aaa atg aaa gcg ccg cta 163 Ser Met Ser Asn Arg Val Val Gln Lys Pro Lys Met Lys Ala Pro Leu 10 15 20 ccc atc cgc gac ggc ctc aac cct tcc cgt gtg cgc ttg ccg ctc gac 211 Pro Ile Arg Asp Gly Leu Asn Pro Ser Arg Val Arg Leu Pro Leu Asp 25 30 35 gcg gcg ccg atc cgc gcc atc gat ttt gtt gaa tac ctc att tcc acg 259 Ala Ala Pro Ile Arg Ala Ile Asp Phe Val Glu Tyr Leu Ile Ser Thr 40 45 50 cag cgc cac cgc aat ccg gcc gac aac gcc gaa gcg ctt caa gcg cgt 307 Gln Arg His Arg Asn Pro Ala Asp Asn Ala Glu Ala Leu Gln Ala Arg 55 60 65 ttc gac gcc gac ctt gtt gtc aac cac tac ggc gag ccc tac gcc ccc 355 Phe Asp Ala Asp Leu Val Val Asn His Tyr Gly Glu Pro Tyr Ala Pro 70 75 80 85 gac acc atg gtt cag ccc gac gac gac att tgg ttc tac cgc atg ccc 403 Asp Thr Met Val Gln Pro Asp Asp Asp Ile Trp Phe Tyr Arg Met Pro 90 95 100 gcc gcc gaa cgg ccg atc cct tac aaa att cat gtc att cac gaa gac 451 Ala Ala Glu Arg Pro Ile Pro Tyr Lys Ile His Val Ile His Glu Asp 105 110 115 gat gac atc ctc gtc att gac aag cca ccc tac cta gca acc atg cct 499 Asp Asp Ile Leu Val Ile Asp Lys Pro Pro Tyr Leu Ala Thr Met Pro 120 125 130 cgt ggc cgc cac atc acc gaa acc gct ctg gtg aaa atg cgt gtg ctg 547 Arg Gly Arg His Ile Thr Glu Thr Ala Leu Val Lys Met Arg Val Leu 135 140 145 act gga aac aac gat ctc acc cca gct cac cgc ctc gat cgc ctg act 595 Thr Gly Asn Asn Asp Leu Thr Pro Ala His Arg Leu Asp Arg Leu Thr 150 155 160 165 tcc ggt gtg tta gtc atg gtg aaa aaa cca gaa ctc cgt ggc gct tac 643 Ser Gly Val Leu Val Met Val Lys Lys Pro Glu Leu Arg Gly Ala Tyr 170 175 180 caa acc ttg ttt gcc cga cgt gag gcg tcc aaa acc tat gag gca atc 691 Gln Thr Leu Phe Ala Arg Arg Glu Ala Ser Lys Thr Tyr Glu Ala Ile 185 190 195 gca gaa ttc gtt cca ggg cta ctt gat gat ggt ccc gcg att tgg gaa 739 Ala Glu Phe Val Pro Gly Leu Leu Asp Asp Gly Pro Ala Ile Trp Glu 200 205 210 tcc cgc atc gaa aaa gaa cgc ggc atc gtg caa gcc ttc gtc gtg gaa 787 Ser Arg Ile Glu Lys Glu Arg Gly Ile Val Gln Ala Phe Val Val Glu 215 220 225 ggc ccc gtc aac gca cgc act gaa ctg gtg tca gtc acc cca gtc gaa 835 Gly Pro Val Asn Ala Arg Thr Glu Leu Val Ser Val Thr Pro Val Glu 230 235 240 245 gac gcc gaa cag agc atc ctc gaa gaa atg cac ggg cca ctc ccc cgc 883 Asp Ala Glu Gln Ser Ile Leu Glu Glu Met His Gly Pro Leu Pro Arg 250 255 260 caa gcg cgc tac gtt cta gcc ccc tca aca ggc aaa acc cac cag ctg 931 Gln Ala Arg Tyr Val Leu Ala Pro Ser Thr Gly Lys Thr His Gln Leu 265 270 275 cgc atc cac atg cgc gac ttc gca gcc ccc atc ctc ggc gac ccc ctc 979 Arg Ile His Met Arg Asp Phe Ala Ala Pro Ile Leu Gly Asp Pro Leu 280 285 290 tac ccc gtc ctc cac gca gtc gac gat gag gac tac acc acc cca atg 1027 Tyr Pro Val Leu His Ala Val Asp Asp Glu Asp Tyr Thr Thr Pro Met 295 300 305 cac ctc atc gcc cgc acg cta acc ttc gtg gat cct caa acc aac gag 1075 His Leu Ile Ala Arg Thr Leu Thr Phe Val Asp Pro Gln Thr Asn Glu 310 315 320 325 gaa cgt acc ttt gtg agt aat cga cct acg gga agt ttg taggcctcgt 1124 Glu Arg Thr Phe Val Ser Asn Arg Pro Thr Gly Ser Leu 330 335 agacatcacc cag 1137 <210> 584 <211> 338 <212> PRT <213> Corynebacterium glutamicum <400> 584 Met Ile Ala Leu Lys Ser Met Ser Asn Arg Val Val Gln Lys Pro Lys 1 5 10 15 Met Lys Ala Pro Leu Pro Ile Arg Asp Gly Leu Asn Pro Ser Arg Val 20 25 30 Arg Leu Pro Leu Asp Ala Ala Pro Ile Arg Ala Ile Asp Phe Val Glu 35 40 45 Tyr Leu Ile Ser Thr Gln Arg His Arg Asn Pro Ala Asp Asn Ala Glu 50 55 60 Ala Leu Gln Ala Arg Phe Asp Ala Asp Leu Val Val Asn His Tyr Gly 65 70 75 80 Glu Pro Tyr Ala Pro Asp Thr Met Val Gln Pro Asp Asp Asp Ile Trp 85 90 95 Phe Tyr Arg Met Pro Ala Ala Glu Arg Pro Ile Pro Tyr Lys Ile His 100 105 110 Val Ile His Glu Asp Asp Asp Ile Leu Val Ile Asp Lys Pro Pro Tyr 115 120 125 Leu Ala Thr Met Pro Arg Gly Arg His Ile Thr Glu Thr Ala Leu Val 130 135 140 Lys Met Arg Val Leu Thr Gly Asn Asn Asp Leu Thr Pro Ala His Arg 145 150 155 160 Leu Asp Arg Leu Thr Ser Gly Val Leu Val Met Val Lys Lys Pro Glu 165 170 175 Leu Arg Gly Ala Tyr Gln Thr Leu Phe Ala Arg Arg Glu Ala Ser Lys 180 185 190 Thr Tyr Glu Ala Ile Ala Glu Phe Val Pro Gly Leu Leu Asp Asp Gly 195 200 205 Pro Ala Ile Trp Glu Ser Arg Ile Glu Lys Glu Arg Gly Ile Val Gln 210 215 220 Ala Phe Val Val Glu Gly Pro Val Asn Ala Arg Thr Glu Leu Val Ser 225 230 235 240 Val Thr Pro Val Glu Asp Ala Glu Gln Ser Ile Leu Glu Glu Met His 245 250 255 Gly Pro Leu Pro Arg Gln Ala Arg Tyr Val Leu Ala Pro Ser Thr Gly 260 265 270 Lys Thr His Gln Leu Arg Ile His Met Arg Asp Phe Ala Ala Pro Ile 275 280 285 Leu Gly Asp Pro Leu Tyr Pro Val Leu His Ala Val Asp Asp Glu Asp 290 295 300 Tyr Thr Thr Pro Met His Leu Ile Ala Arg Thr Leu Thr Phe Val Asp 305 310 315 320 Pro Gln Thr Asn Glu Glu Arg Thr Phe Val Ser Asn Arg Pro Thr Gly 325 330 335 Ser Leu <210> 585 <211> 1281 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1258) <223> RXC01711 <400> 585 tctcgtgagt ttctccccgg tagcaccttc tatatcagcc cccacgccgc gtcggagcag 60 gtgggatagc atcggcaacg cggttgcatg gccgttggcc atg ttg ttg atg gcg 115 Met Leu Leu Met Ala 1 5 cat cgc ttc ttc gtg ctt gcg att aac ggc gca gtc acc gac gat ttc 163 His Arg Phe Phe Val Leu Ala Ile Asn Gly Ala Val Thr Asp Asp Phe 10 15 20 acg acg gtt tat agt gct tta cga cgt ttc gtt gaa ggt att ccg gtc 211 Thr Thr Val Tyr Ser Ala Leu Arg Arg Phe Val Glu Gly Ile Pro Val 25 30 35 tac aac gag gtc tac cac ttc gtc gat ccg cac tac ctc tat aac ccg 259 Tyr Asn Glu Val Tyr His Phe Val Asp Pro His Tyr Leu Tyr Asn Pro 40 45 50 ggc gcc acc ctc cta ttg gca cca ttg gga tat atc acc cat ttc acg 307 Gly Ala Thr Leu Leu Leu Ala Pro Leu Gly Tyr Ile Thr His Phe Thr 55 60 65 ttg gct cgg tgg atg ttc atc gcg gtg aac ctc ctt gcc att gtt tta 355 Leu Ala Arg Trp Met Phe Ile Ala Val Asn Leu Leu Ala Ile Val Leu 70 75 80 85 gcg ttc ggg ctg ctg acc aga ctc tcc ggt tgg gcg ctg cgc agc atg 403 Ala Phe Gly Leu Leu Thr Arg Leu Ser Gly Trp Ala Leu Arg Ser Met 90 95 100 gtg tgg ccg att gcg atc gcc ttg gcg atg ctg aca gaa acc gtg caa 451 Val Trp Pro Ile Ala Ile Ala Leu Ala Met Leu Thr Glu Thr Val Gln 105 110 115 aac acc ctc att ttc tcc aac atc aac ggc atc ctg ctg ctc atg ttg 499 Asn Thr Leu Ile Phe Ser Asn Ile Asn Gly Ile Leu Leu Leu Met Leu 120 125 130 gcg att ttc ctg tgg tgc gtg gtg cac aaa aaa tcc tgg ttg ggc gga 547 Ala Ile Phe Leu Trp Cys Val Val His Lys Lys Ser Trp Leu Gly Gly 135 140 145 cta gtc att ggt ttg gcc att ttg atc aaa ccc atg ttc ctg cca ctt 595 Leu Val Ile Gly Leu Ala Ile Leu Ile Lys Pro Met Phe Leu Pro Leu 150 155 160 165 ctc ttc cta cct ttg gtg aaa aag caa tgg gga tcg ctc atc ctc ggc 643 Leu Phe Leu Pro Leu Val Lys Lys Gln Trp Gly Ser Leu Ile Leu Gly 170 175 180 att tta acc cca gtg att ttc aat gca gtg gcc tgg ttc tta gtt ccg 691 Ile Leu Thr Pro Val Ile Phe Asn Ala Val Ala Trp Phe Leu Val Pro 185 190 195 gga gca tct gaa tac gtc acc cgc acg atg ccc tac ctt ggt gaa act 739 Gly Ala Ser Glu Tyr Val Thr Arg Thr Met Pro Tyr Leu Gly Glu Thr 200 205 210 cga gat ttt gcc aac agc tca ctc cca ggc ttg gcc atc tat ttc gga 787 Arg Asp Phe Ala Asn Ser Ser Leu Pro Gly Leu Ala Ile Tyr Phe Gly 215 220 225 atg ccc acc tgg atg gaa atc acc tgg ttc ctc atc ttc ggc gca atg 835 Met Pro Thr Trp Met Glu Ile Thr Trp Phe Leu Ile Phe Gly Ala Met 230 235 240 245 gtc ggc ctc gca gtg ctg gca ctc ctg aga ttc cgt aac acc gag cca 883 Val Gly Leu Ala Val Leu Ala Leu Leu Arg Phe Arg Asn Thr Glu Pro 250 255 260 tac ttc tgg gca gca acc acc acc ggt gta ctc ctg act ggc gta ttc 931 Tyr Phe Trp Ala Ala Thr Thr Thr Gly Val Leu Leu Thr Gly Val Phe 265 270 275 ttc ctg tcc tca ctg gga cag atg tac tac tcc atg atg atc ttc cct 979 Phe Leu Ser Ser Leu Gly Gln Met Tyr Tyr Ser Met Met Ile Phe Pro 280 285 290 atg atc ttc acc ctg ctc gga agc cga tcc gta ttc cac aac tgg gtt 1027 Met Ile Phe Thr Leu Leu Gly Ser Arg Ser Val Phe His Asn Trp Val 295 300 305 gcc tgg gtc gcc gcc tac ttc tta cta tcc cct gac act ttc acc tcc 1075 Ala Trp Val Ala Ala Tyr Phe Leu Leu Ser Pro Asp Thr Phe Thr Ser 310 315 320 325 cag cga cta ccc gat gta gcc cgc tgg atg gaa ttt ttc agc gcg acc 1123 Gln Arg Leu Pro Asp Val Ala Arg Trp Met Glu Phe Phe Ser Ala Thr 330 335 340 gtt ggt tgg gga cta ttg ata gtg gtt aca ttt gtc tcg gcg cta atc 1171 Val Gly Trp Gly Leu Leu Ile Val Val Thr Phe Val Ser Ala Leu Ile 345 350 355 tgg ttt att ggt gat atc cga gcc aag gga act ccg agc tca ccc att 1219 Trp Phe Ile Gly Asp Ile Arg Ala Lys Gly Thr Pro Ser Ser Pro Ile 360 365 370 acc act gat cca acg cac gac cat ctt gag agg aca gca tgacagactt 1268 Thr Thr Asp Pro Thr His Asp His Leu Glu Arg Thr Ala 375 380 385 caaactcatc agc 1281 <210> 586 <211> 386 <212> PRT <213> Corynebacterium glutamicum <400> 586 Met Leu Leu Met Ala His Arg Phe Phe Val Leu Ala Ile Asn Gly Ala 1 5 10 15 Val Thr Asp Asp Phe Thr Thr Val Tyr Ser Ala Leu Arg Arg Phe Val 20 25 30 Glu Gly Ile Pro Val Tyr Asn Glu Val Tyr His Phe Val Asp Pro His 35 40 45 Tyr Leu Tyr Asn Pro Gly Ala Thr Leu Leu Leu Ala Pro Leu Gly Tyr 50 55 60 Ile Thr His Phe Thr Leu Ala Arg Trp Met Phe Ile Ala Val Asn Leu 65 70 75 80 Leu Ala Ile Val Leu Ala Phe Gly Leu Leu Thr Arg Leu Ser Gly Trp 85 90 95 Ala Leu Arg Ser Met Val Trp Pro Ile Ala Ile Ala Leu Ala Met Leu 100 105 110 Thr Glu Thr Val Gln Asn Thr Leu Ile Phe Ser Asn Ile Asn Gly Ile 115 120 125 Leu Leu Leu Met Leu Ala Ile Phe Leu Trp Cys Val Val His Lys Lys 130 135 140 Ser Trp Leu Gly Gly Leu Val Ile Gly Leu Ala Ile Leu Ile Lys Pro 145 150 155 160 Met Phe Leu Pro Leu Leu Phe Leu Pro Leu Val Lys Lys Gln Trp Gly 165 170 175 Ser Leu Ile Leu Gly Ile Leu Thr Pro Val Ile Phe Asn Ala Val Ala 180 185 190 Trp Phe Leu Val Pro Gly Ala Ser Glu Tyr Val Thr Arg Thr Met Pro 195 200 205 Tyr Leu Gly Glu Thr Arg Asp Phe Ala Asn Ser Ser Leu Pro Gly Leu 210 215 220 Ala Ile Tyr Phe Gly Met Pro Thr Trp Met Glu Ile Thr Trp Phe Leu 225 230 235 240 Ile Phe Gly Ala Met Val Gly Leu Ala Val Leu Ala Leu Leu Arg Phe 245 250 255 Arg Asn Thr Glu Pro Tyr Phe Trp Ala Ala Thr Thr Thr Gly Val Leu 260 265 270 Leu Thr Gly Val Phe Phe Leu Ser Ser Leu Gly Gln Met Tyr Tyr Ser 275 280 285 Met Met Ile Phe Pro Met Ile Phe Thr Leu Leu Gly Ser Arg Ser Val 290 295 300 Phe His Asn Trp Val Ala Trp Val Ala Ala Tyr Phe Leu Leu Ser Pro 305 310 315 320 Asp Thr Phe Thr Ser Gln Arg Leu Pro Asp Val Ala Arg Trp Met Glu 325 330 335 Phe Phe Ser Ala Thr Val Gly Trp Gly Leu Leu Ile Val Val Thr Phe 340 345 350 Val Ser Ala Leu Ile Trp Phe Ile Gly Asp Ile Arg Ala Lys Gly Thr 355 360 365 Pro Ser Ser Pro Ile Thr Thr Asp Pro Thr His Asp His Leu Glu Arg 370 375 380 Thr Ala 385 <210> 587 <211> 777 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(754) <223> RXC02380 <400> 587 gcagattttt gacgaagtcg catcgtggat tgaagctgcc taaaaactcg cgaggacgca 60 tgctcagcaa ggtggtgtgc gaacactata ctgtccactc atg act aca acg gtg 115 Met Thr Thr Thr Val 1 5 aaa cgc cgc gct cgc att ggc atc atg ggt ggc aca ttt gac ccc att 163 Lys Arg Arg Ala Arg Ile Gly Ile Met Gly Gly Thr Phe Asp Pro Ile 10 15 20 cat aat ggt cac ctt gtg gcg ggc tca gag gta gcg gat cga ttc gat 211 His Asn Gly His Leu Val Ala Gly Ser Glu Val Ala Asp Arg Phe Asp 25 30 35 ctt gat ctg gtg gtg tac gtt ccc acc gga cag cca tgg caa aag gcg 259 Leu Asp Leu Val Val Tyr Val Pro Thr Gly Gln Pro Trp Gln Lys Ala 40 45 50 aac aag aaa gtc agc cca gcg gaa gat cgt tac ctg atg acg gtg atc 307 Asn Lys Lys Val Ser Pro Ala Glu Asp Arg Tyr Leu Met Thr Val Ile 55 60 65 gcc act gcc tct aat cca cgg ttt atg gta tcg cgg gtt gat att gat 355 Ala Thr Ala Ser Asn Pro Arg Phe Met Val Ser Arg Val Asp Ile Asp 70 75 80 85 cgg gga ggg gat act tac acg atc gat acc ctg caa gat ttg agc aag 403 Arg Gly Gly Asp Thr Tyr Thr Ile Asp Thr Leu Gln Asp Leu Ser Lys 90 95 100 caa tac ccg gac gcc cag ctg tac ttc atc acc ggt gcc gat gca ctg 451 Gln Tyr Pro Asp Ala Gln Leu Tyr Phe Ile Thr Gly Ala Asp Ala Leu 105 110 115 gca cag atc gtg acg tgg cgc gat tgg gag aaa acc ttc gaa ctt gcc 499 Ala Gln Ile Val Thr Trp Arg Asp Trp Glu Lys Thr Phe Glu Leu Ala 120 125 130 cac ttc gtt gga gtg act cga ccc ggt tat gaa ttg gat gga aac atc 547 His Phe Val Gly Val Thr Arg Pro Gly Tyr Glu Leu Asp Gly Asn Ile 135 140 145 att ccg gaa atg cac caa gat cga gtc tca ttg gtg gat atc ccc gcc 595 Ile Pro Glu Met His Gln Asp Arg Val Ser Leu Val Asp Ile Pro Ala 150 155 160 165 atg gct att tcc tcc acg gac tgc aga gaa cgc tcc agc gaa gaa cgc 643 Met Ala Ile Ser Ser Thr Asp Cys Arg Glu Arg Ser Ser Glu Glu Arg 170 175 180 cct gtt tgg tat ctt gtc cct gat ggc gtg gtg caa tac att gcc aaa 691 Pro Val Trp Tyr Leu Val Pro Asp Gly Val Val Gln Tyr Ile Ala Lys 185 190 195 cgc caa ctc tat cga cct gaa gga tcc gat aag gat atg gat ccc aag 739 Arg Gln Leu Tyr Arg Pro Glu Gly Ser Asp Lys Asp Met Asp Pro Lys 200 205 210 ggc caa aac caa gca taaatctagt caaaagtttc aac 777 Gly Gln Asn Gln Ala 215 <210> 588 <211> 218 <212> PRT <213> Corynebacterium glutamicum <400> 588 Met Thr Thr Thr Val Lys Arg Arg Ala Arg Ile Gly Ile Met Gly Gly 1 5 10 15 Thr Phe Asp Pro Ile His Asn Gly His Leu Val Ala Gly Ser Glu Val 20 25 30 Ala Asp Arg Phe Asp Leu Asp Leu Val Val Tyr Val Pro Thr Gly Gln 35 40 45 Pro Trp Gln Lys Ala Asn Lys Lys Val Ser Pro Ala Glu Asp Arg Tyr 50 55 60 Leu Met Thr Val Ile Ala Thr Ala Ser Asn Pro Arg Phe Met Val Ser 65 70 75 80 Arg Val Asp Ile Asp Arg Gly Gly Asp Thr Tyr Thr Ile Asp Thr Leu 85 90 95 Gln Asp Leu Ser Lys Gln Tyr Pro Asp Ala Gln Leu Tyr Phe Ile Thr 100 105 110 Gly Ala Asp Ala Leu Ala Gln Ile Val Thr Trp Arg Asp Trp Glu Lys 115 120 125 Thr Phe Glu Leu Ala His Phe Val Gly Val Thr Arg Pro Gly Tyr Glu 130 135 140 Leu Asp Gly Asn Ile Ile Pro Glu Met His Gln Asp Arg Val Ser Leu 145 150 155 160 Val Asp Ile Pro Ala Met Ala Ile Ser Ser Thr Asp Cys Arg Glu Arg 165 170 175 Ser Ser Glu Glu Arg Pro Val Trp Tyr Leu Val Pro Asp Gly Val Val 180 185 190 Gln Tyr Ile Ala Lys Arg Gln Leu Tyr Arg Pro Glu Gly Ser Asp Lys 195 200 205 Asp Met Asp Pro Lys Gly Gln Asn Gln Ala 210 215 <210> 589 <211> 777 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(754) <223> FRXA02380 <400> 589 gcagattttt gacgaagtcg catcgtggat tgaagctgcc taaaaactcg cgaggacgca 60 tgctcagcaa ggtggtgtgc gaacactata ctgtccactc atg act aca acg gtg 115 Met Thr Thr Thr Val 1 5 aaa cgc cgc gct cgc att ggc atc atg ggt ggc aca ttt gac ccc att 163 Lys Arg Arg Ala Arg Ile Gly Ile Met Gly Gly Thr Phe Asp Pro Ile 10 15 20 cat aat ggt cac ctt gtg gcg ggc tca gag gta gcg gat cga ttc gat 211 His Asn Gly His Leu Val Ala Gly Ser Glu Val Ala Asp Arg Phe Asp 25 30 35 ctt gat ctg gtg gtg tac gtt ccc acc gga cag cca tgg caa aag gcg 259 Leu Asp Leu Val Val Tyr Val Pro Thr Gly Gln Pro Trp Gln Lys Ala 40 45 50 aac aag aaa gtc agc cca gcg gaa gat cgt tac ctg atg acg gtg atc 307 Asn Lys Lys Val Ser Pro Ala Glu Asp Arg Tyr Leu Met Thr Val Ile 55 60 65 gcc act gcc tct aat cca cgg ttt atg gta tcg cgg gtt gat att gat 355 Ala Thr Ala Ser Asn Pro Arg Phe Met Val Ser Arg Val Asp Ile Asp 70 75 80 85 cgg gga ggg gat act tac acg atc gat acc ctg caa gat ttg agc aag 403 Arg Gly Gly Asp Thr Tyr Thr Ile Asp Thr Leu Gln Asp Leu Ser Lys 90 95 100 caa tac ccg gac gcc cag ctg tac ttc atc acc ggt gcc gat gca ctg 451 Gln Tyr Pro Asp Ala Gln Leu Tyr Phe Ile Thr Gly Ala Asp Ala Leu 105 110 115 gca cag atc gtg acg tgg cgc gat tgg gag aaa acc ttc gaa ctt gcc 499 Ala Gln Ile Val Thr Trp Arg Asp Trp Glu Lys Thr Phe Glu Leu Ala 120 125 130 cac ttc gtt gga gtg act cga ccc ggt tat gaa ttg gat gga aac atc 547 His Phe Val Gly Val Thr Arg Pro Gly Tyr Glu Leu Asp Gly Asn Ile 135 140 145 att ccg gaa atg cac caa gat cga gtc tca ttg gtg gat atc ccc gcc 595 Ile Pro Glu Met His Gln Asp Arg Val Ser Leu Val Asp Ile Pro Ala 150 155 160 165 atg gct att tcc tcc acg gac tgc aga gaa cgc tcc agc gaa gaa cgc 643 Met Ala Ile Ser Ser Thr Asp Cys Arg Glu Arg Ser Ser Glu Glu Arg 170 175 180 cct gtt tgg tat ctt gtc cct gat ggc gtg gtg caa tac att gcc aaa 691 Pro Val Trp Tyr Leu Val Pro Asp Gly Val Val Gln Tyr Ile Ala Lys 185 190 195 cgc caa ctc tat cga cct gaa gga tcc gat aag gat atg gat ccc aag 739 Arg Gln Leu Tyr Arg Pro Glu Gly Ser Asp Lys Asp Met Asp Pro Lys 200 205 210 ggc caa aac caa gca taaatctagt caaaagtttc aac 777 Gly Gln Asn Gln Ala 215 <210> 590 <211> 218 <212> PRT <213> Corynebacterium glutamicum <400> 590 Met Thr Thr Thr Val Lys Arg Arg Ala Arg Ile Gly Ile Met Gly Gly 1 5 10 15 Thr Phe Asp Pro Ile His Asn Gly His Leu Val Ala Gly Ser Glu Val 20 25 30 Ala Asp Arg Phe Asp Leu Asp Leu Val Val Tyr Val Pro Thr Gly Gln 35 40 45 Pro Trp Gln Lys Ala Asn Lys Lys Val Ser Pro Ala Glu Asp Arg Tyr 50 55 60 Leu Met Thr Val Ile Ala Thr Ala Ser Asn Pro Arg Phe Met Val Ser 65 70 75 80 Arg Val Asp Ile Asp Arg Gly Gly Asp Thr Tyr Thr Ile Asp Thr Leu 85 90 95 Gln Asp Leu Ser Lys Gln Tyr Pro Asp Ala Gln Leu Tyr Phe Ile Thr 100 105 110 Gly Ala Asp Ala Leu Ala Gln Ile Val Thr Trp Arg Asp Trp Glu Lys 115 120 125 Thr Phe Glu Leu Ala His Phe Val Gly Val Thr Arg Pro Gly Tyr Glu 130 135 140 Leu Asp Gly Asn Ile Ile Pro Glu Met His Gln Asp Arg Val Ser Leu 145 150 155 160 Val Asp Ile Pro Ala Met Ala Ile Ser Ser Thr Asp Cys Arg Glu Arg 165 170 175 Ser Ser Glu Glu Arg Pro Val Trp Tyr Leu Val Pro Asp Gly Val Val 180 185 190 Gln Tyr Ile Ala Lys Arg Gln Leu Tyr Arg Pro Glu Gly Ser Asp Lys 195 200 205 Asp Met Asp Pro Lys Gly Gln Asn Gln Ala 210 215 <210> 591 <211> 594 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(571) <223> RXC02921 <400> 591 tggaaaactg ggaagggttg acgttgcgga atctctccgc agcgtcggtt cggaccctaa 60 aaaagggtga ggaaccacat gagctgtttt aaggaatttt gtg tct gca ctt gaa 115 Val Ser Ala Leu Glu 1 5 gag tcg atc cgc atc gcg acc atc gcg gcg aaa gca gcg gat gaa aag 163 Glu Ser Ile Arg Ile Ala Thr Ile Ala Ala Lys Ala Ala Asp Glu Lys 10 15 20 aag gcc gat gac atc gct gtc atc gat gtc tct gac atg atc gca atc 211 Lys Ala Asp Asp Ile Ala Val Ile Asp Val Ser Asp Met Ile Ala Ile 25 30 35 acc gat tgc ttt gtt gtt gca tct gct gac aat gag cgc cag gtg ggc 259 Thr Asp Cys Phe Val Val Ala Ser Ala Asp Asn Glu Arg Gln Val Gly 40 45 50 gcc att gtt gag gag atc gaa gat gag atg acc aag gct ggt ttc gag 307 Ala Ile Val Glu Glu Ile Glu Asp Glu Met Thr Lys Ala Gly Phe Glu 55 60 65 cct aag cgc cgt gaa ggc aac cgc gaa aac cgt tgg gtt ctc ctt gac 355 Pro Lys Arg Arg Glu Gly Asn Arg Glu Asn Arg Trp Val Leu Leu Asp 70 75 80 85 tac gga ttg gtt gtt atc cac gtt cag cga cag gca gag cgc gag ttc 403 Tyr Gly Leu Val Val Ile His Val Gln Arg Gln Ala Glu Arg Glu Phe 90 95 100 tac gga ctg gat cgt ctg tac cgc gac tgc cca ctc att gaa att gaa 451 Tyr Gly Leu Asp Arg Leu Tyr Arg Asp Cys Pro Leu Ile Glu Ile Glu 105 110 115 gga ctt gaa acc ttc aag cgt gaa tcc tcc tgg tct gat gag gcg gat 499 Gly Leu Glu Thr Phe Lys Arg Glu Ser Ser Trp Ser Asp Glu Ala Asp 120 125 130 atc cgc aac atc gac agc att gat gaa ctc cca cct ttg cca gct gaa 547 Ile Arg Asn Ile Asp Ser Ile Asp Glu Leu Pro Pro Leu Pro Ala Glu 135 140 145 tac gag cct ggc tac gag gac gat taagaggtag tcctgtgact cgt 594 Tyr Glu Pro Gly Tyr Glu Asp Asp 150 155 <210> 592 <211> 157 <212> PRT <213> Corynebacterium glutamicum <400> 592 Val Ser Ala Leu Glu Glu Ser Ile Arg Ile Ala Thr Ile Ala Ala Lys 1 5 10 15 Ala Ala Asp Glu Lys Lys Ala Asp Asp Ile Ala Val Ile Asp Val Ser 20 25 30 Asp Met Ile Ala Ile Thr Asp Cys Phe Val Val Ala Ser Ala Asp Asn 35 40 45 Glu Arg Gln Val Gly Ala Ile Val Glu Glu Ile Glu Asp Glu Met Thr 50 55 60 Lys Ala Gly Phe Glu Pro Lys Arg Arg Glu Gly Asn Arg Glu Asn Arg 65 70 75 80 Trp Val Leu Leu Asp Tyr Gly Leu Val Val Ile His Val Gln Arg Gln 85 90 95 Ala Glu Arg Glu Phe Tyr Gly Leu Asp Arg Leu Tyr Arg Asp Cys Pro 100 105 110 Leu Ile Glu Ile Glu Gly Leu Glu Thr Phe Lys Arg Glu Ser Ser Trp 115 120 125 Ser Asp Glu Ala Asp Ile Arg Asn Ile Asp Ser Ile Asp Glu Leu Pro 130 135 140 Pro Leu Pro Ala Glu Tyr Glu Pro Gly Tyr Glu Asp Asp 145 150 155 <210> 593 <211> 3075 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3052) <223> RXC01434 <400> 593 ggtttcctgc gcaccgtgat gattggtgcg gcgctgtcgc cggccatcgc ttcggcgttc 60 aacactgcca acacgctgcc caacctgatc actggaaatc gtg ttg ggt gcg gtg 115 Val Leu Gly Ala Val 1 5 ctg aca tcg ctg gtt att ccg gtc ctt acc cgc gcg gaa aaa gaa gac 163 Leu Thr Ser Leu Val Ile Pro Val Leu Thr Arg Ala Glu Lys Glu Asp 10 15 20 gcc gac ggc ggt tcc ggg ttc ttc agg cgg ctg ctc acc ctg tcg gtg 211 Ala Asp Gly Gly Ser Gly Phe Phe Arg Arg Leu Leu Thr Leu Ser Val 25 30 35 acg ctg ctg ggt ggt gtc acc atc ctg tcg att atc ggc gcg ccg ctg 259 Thr Leu Leu Gly Gly Val Thr Ile Leu Ser Ile Ile Gly Ala Pro Leu 40 45 50 ctg aca cgg atg atg ctg tcc tct gag gga caa gtc aac gtg gtc atg 307 Leu Thr Arg Met Met Leu Ser Ser Glu Gly Gln Val Asn Val Val Met 55 60 65 tcc acg gcc ttt gcg tat tgg ctg ctg cca cag att ttc ttc tac ggc 355 Ser Thr Ala Phe Ala Tyr Trp Leu Leu Pro Gln Ile Phe Phe Tyr Gly 70 75 80 85 ctg ttt gcc ctg ttc atg gct gtg ttg aac acc cgt gaa gtg ttc aaa 403 Leu Phe Ala Leu Phe Met Ala Val Leu Asn Thr Arg Glu Val Phe Lys 90 95 100 ccc ggc gcg tgg gca cct gtt gtc aac aat gtg atc acc ttg acc gtg 451 Pro Gly Ala Trp Ala Pro Val Val Asn Asn Val Ile Thr Leu Thr Val 105 110 115 ctg ggc gtg tac atg gtg ctg cct gcg cgt ttg cac ccg cat gag cag 499 Leu Gly Val Tyr Met Val Leu Pro Ala Arg Leu His Pro His Glu Gln 120 125 130 gtg ggc att ttt gat ccg cag atc att ttc ctc ggc gtg ggc acc acc 547 Val Gly Ile Phe Asp Pro Gln Ile Ile Phe Leu Gly Val Gly Thr Thr 135 140 145 ctt ggt gtg gtt gca cag tgt cta atc atg att ccg tac ctg cgt cgc 595 Leu Gly Val Val Ala Gln Cys Leu Ile Met Ile Pro Tyr Leu Arg Arg 150 155 160 165 gcg ggc att gat atg cgc cct ctg tgg ggt atc gat gcg cgt ttg aag 643 Ala Gly Ile Asp Met Arg Pro Leu Trp Gly Ile Asp Ala Arg Leu Lys 170 175 180 caa ttc ggt ggc atg gcg atg gcg atc atc gtg tac gtg gca atc tcc 691 Gln Phe Gly Gly Met Ala Met Ala Ile Ile Val Tyr Val Ala Ile Ser 185 190 195 cag ttc ggt tac atc atc acc act cgc att gcg tcg att gca gac gat 739 Gln Phe Gly Tyr Ile Ile Thr Thr Arg Ile Ala Ser Ile Ala Asp Asp 200 205 210 gct gcg ccg ttt att tat cag cag cac tgg atg ttg ctg caa gtt cct 787 Ala Ala Pro Phe Ile Tyr Gln Gln His Trp Met Leu Leu Gln Val Pro 215 220 225 tat ggc atc atc ggc gtc acc ttg ctc acc gcg att atg ccg cga ctg 835 Tyr Gly Ile Ile Gly Val Thr Leu Leu Thr Ala Ile Met Pro Arg Leu 230 235 240 245 tcc cgc aac gcg gca gac ggc gat gat agg gca gta gtc tct gac ctt 883 Ser Arg Asn Ala Ala Asp Gly Asp Asp Arg Ala Val Val Ser Asp Leu 250 255 260 cag ttg ggt tcc aag cta acc ttc atc gca ctg atc ccc atc gtg gtg 931 Gln Leu Gly Ser Lys Leu Thr Phe Ile Ala Leu Ile Pro Ile Val Val 265 270 275 ttc ttc acc gcc ttc ggt gtc cct att gcc aat ggc ctt ttt gcc tac 979 Phe Phe Thr Ala Phe Gly Val Pro Ile Ala Asn Gly Leu Phe Ala Tyr 280 285 290 ggc caa ttc gat gcc aac gcc gcc aac atc ctt ggt tgg act ctg agc 1027 Gly Gln Phe Asp Ala Asn Ala Ala Asn Ile Leu Gly Trp Thr Leu Ser 295 300 305 ttc tct gct ttc acg ctg att cct tac gct ttg gtg ctg cta cat ctg 1075 Phe Ser Ala Phe Thr Leu Ile Pro Tyr Ala Leu Val Leu Leu His Leu 310 315 320 325 cgt gtg ttt tat gcg cgt gaa gag gtc tgg acc cca acc ttc atc atc 1123 Arg Val Phe Tyr Ala Arg Glu Glu Val Trp Thr Pro Thr Phe Ile Ile 330 335 340 gcc ggc atc acc gcc acc aag gtc gtg ctt tcc ctg ttg gca ccg ctg 1171 Ala Gly Ile Thr Ala Thr Lys Val Val Leu Ser Leu Leu Ala Pro Leu 345 350 355 ctg tcg agc tcc ccg gag cgt gtg gtg gtg ctt ctt ggt gcg gcc aac 1219 Leu Ser Ser Ser Pro Glu Arg Val Val Val Leu Leu Gly Ala Ala Asn 360 365 370 ggt ttc agt ttc atc acc ggc gcg gtc atc ggc gcg tat ctg ttg cgc 1267 Gly Phe Ser Phe Ile Thr Gly Ala Val Ile Gly Ala Tyr Leu Leu Arg 375 380 385 aac aaa ctc ggc ctg ttg ggt atg cgc tct ttg gct aaa acc tcc ctg 1315 Asn Lys Leu Gly Leu Leu Gly Met Arg Ser Leu Ala Lys Thr Ser Leu 390 395 400 405 tgg gcg ttg ggc tct gcg gcg gtt ggt gca gca gca gca tgg gcg ttg 1363 Trp Ala Leu Gly Ser Ala Ala Val Gly Ala Ala Ala Ala Trp Ala Leu 410 415 420 ggg tgg ctg att caa gcc gtc gtg ggc gat ttc ttg ctg ggc act cta 1411 Gly Trp Leu Ile Gln Ala Val Val Gly Asp Phe Leu Leu Gly Thr Leu 425 430 435 agc tcc gta ggc tac ttg ttg aac ctg gct gtg ttg ggt gtc ttc ttc 1459 Ser Ser Val Gly Tyr Leu Leu Asn Leu Ala Val Leu Gly Val Phe Phe 440 445 450 atc ttc gtc acc ggc atc gtg ttg tca cgt tct ggt ttg ccg gag gtc 1507 Ile Phe Val Thr Gly Ile Val Leu Ser Arg Ser Gly Leu Pro Glu Val 455 460 465 caa aac ttg ggc cag gca ctg acc cgc atc cca ggt ttg agc cgg ttt 1555 Gln Asn Leu Gly Gln Ala Leu Thr Arg Ile Pro Gly Leu Ser Arg Phe 470 475 480 485 att cgc ccg aat acc aag atc tct ttg gat gtc ggc gaa gtc tcc gag 1603 Ile Arg Pro Asn Thr Lys Ile Ser Leu Asp Val Gly Glu Val Ser Glu 490 495 500 cag gat ttc tcc acc cag ctg gtc gcg cca agc gag ttc gca gca acc 1651 Gln Asp Phe Ser Thr Gln Leu Val Ala Pro Ser Glu Phe Ala Ala Thr 505 510 515 cct gtg ccg cca ccg atg tcc gcc ggt att gtc cgc gga cct cgc ctg 1699 Pro Val Pro Pro Pro Met Ser Ala Gly Ile Val Arg Gly Pro Arg Leu 520 525 530 gtt ccc ggc gcc cca gtc ggc gac ggt cgt ttc cgt ctg ctc gcc gat 1747 Val Pro Gly Ala Pro Val Gly Asp Gly Arg Phe Arg Leu Leu Ala Asp 535 540 545 cac ggc ggc gtc caa ggc gcg cgt ttc tgg cag gcc cgc gag atc gcc 1795 His Gly Gly Val Gln Gly Ala Arg Phe Trp Gln Ala Arg Glu Ile Ala 550 555 560 565 acc ggc aag gaa gtc gcg ctg atc ttt gtg gat act tcc ggc aac gcc 1843 Thr Gly Lys Glu Val Ala Leu Ile Phe Val Asp Thr Ser Gly Asn Ala 570 575 580 cca ttt gcg cca ctg tct tcg gca gcc gca gcg ggc atc gcc tac gag 1891 Pro Phe Ala Pro Leu Ser Ser Ala Ala Ala Ala Gly Ile Ala Tyr Glu 585 590 595 gtg cag cgc cgc acc aag aag ctg gcc agc ttg ggc agc ttg gcg gta 1939 Val Gln Arg Arg Thr Lys Lys Leu Ala Ser Leu Gly Ser Leu Ala Val 600 605 610 gcc ccc aac atc cac tcc gag gcg tac cgc aac ggt tgc ctc att gtg 1987 Ala Pro Asn Ile His Ser Glu Ala Tyr Arg Asn Gly Cys Leu Ile Val 615 620 625 gcc gat tgg gtg cct ggc tcc agc ttg agc gcc gtc gcg gaa tcc ggt 2035 Ala Asp Trp Val Pro Gly Ser Ser Leu Ser Ala Val Ala Glu Ser Gly 630 635 640 645 gcc gat ccc cgc gcc gcc gcg ttc gcg ctc gcg gaa cta act gaa acc 2083 Ala Asp Pro Arg Ala Ala Ala Phe Ala Leu Ala Glu Leu Thr Glu Thr 650 655 660 atc ggc gag gcc cac gag atg ggt atc ccg gcc ggc ttg gac aac aag 2131 Ile Gly Glu Ala His Glu Met Gly Ile Pro Ala Gly Leu Asp Asn Lys 665 670 675 tgc cga att cgt atc aac acc gac ggc cat gcc gtc ctc gcc ttg ccg 2179 Cys Arg Ile Arg Ile Asn Thr Asp Gly His Ala Val Leu Ala Leu Pro 680 685 690 gcg att ttg ccc gat gcc tca gag ctc cgc gac gcc aag tcc ctg gcc 2227 Ala Ile Leu Pro Asp Ala Ser Glu Leu Arg Asp Ala Lys Ser Leu Ala 695 700 705 tcg gcc gcc gag atg ctt atc gac gcg acc ctc gct ccc agc gac gtc 2275 Ser Ala Ala Glu Met Leu Ile Asp Ala Thr Leu Ala Pro Ser Asp Val 710 715 720 725 aag gca atg gtc act gaa gcc cag ggg cta gct aca gaa gac aat ccc 2323 Lys Ala Met Val Thr Glu Ala Gln Gly Leu Ala Thr Glu Asp Asn Pro 730 735 740 gat tac gca tca ctt gcc atg gcg atg cgc acc tgc gga ctg ttc acc 2371 Asp Tyr Ala Ser Leu Ala Met Ala Met Arg Thr Cys Gly Leu Phe Thr 745 750 755 gag gaa cca acc cac ctt gtg gtg aag aag gaa aag aca cca aag cct 2419 Glu Glu Pro Thr His Leu Val Val Lys Lys Glu Lys Thr Pro Lys Pro 760 765 770 gcg aca cgt gat ggt ttc ggt gcc tcc gac tac acc gtc aag ggc atg 2467 Ala Thr Arg Asp Gly Phe Gly Ala Ser Asp Tyr Thr Val Lys Gly Met 775 780 785 gca gcc atc gcc gct gtg gtg atc atc ttg gtt tcc ctg gtg gcc gcc 2515 Ala Ala Ile Ala Ala Val Val Ile Ile Leu Val Ser Leu Val Ala Ala 790 795 800 805 ggt acc gcg ttc ctc acc agc ttc ttc ggc agc agc acc aac gaa caa 2563 Gly Thr Ala Phe Leu Thr Ser Phe Phe Gly Ser Ser Thr Asn Glu Gln 810 815 820 tcc ccg ttg gcc tct gtt gaa gcc acc acc tct gca aca cca gaa cct 2611 Ser Pro Leu Ala Ser Val Glu Ala Thr Thr Ser Ala Thr Pro Glu Pro 825 830 835 gtg ggg cca ccg gtc tac ctg gat ctg gat caa gcc cgc acg tgg gat 2659 Val Gly Pro Pro Val Tyr Leu Asp Leu Asp Gln Ala Arg Thr Trp Asp 840 845 850 gac ggt gca gga aca gat gtc acc gac gtc acc gac ggc aac acc tcc 2707 Asp Gly Ala Gly Thr Asp Val Thr Asp Val Thr Asp Gly Asn Thr Ser 855 860 865 acc gca tgg acc tcc acc ggc ggc gac ggc ctc cta gtt gac ctg tcc 2755 Thr Ala Trp Thr Ser Thr Gly Gly Asp Gly Leu Leu Val Asp Leu Ser 870 875 880 885 acg cct gcc cgc ctc gac cgc gtc atc ttg acc acc ggc acc ggc tcc 2803 Thr Pro Ala Arg Leu Asp Arg Val Ile Leu Thr Thr Gly Thr Gly Ser 890 895 900 gac agc aac gtg acc tcg acc gtg aag atc tac gca ttc aac gac gcc 2851 Asp Ser Asn Val Thr Ser Thr Val Lys Ile Tyr Ala Phe Asn Asp Ala 905 910 915 tca cca cac tcc ctg tcg gaa ggc atc gag atc ggc acc gtg gat tat 2899 Ser Pro His Ser Leu Ser Glu Gly Ile Glu Ile Gly Thr Val Asp Tyr 920 925 930 tcc ggc cgc agt ctc agc cac agc atc cgc gat tcc tcc aag ctt ccg 2947 Ser Gly Arg Ser Leu Ser His Ser Ile Arg Asp Ser Ser Lys Leu Pro 935 940 945 ggt cag gtg gaa tcc gtg gtg att ctg gtc gat gag gtt cgt tcc tca 2995 Gly Gln Val Glu Ser Val Val Ile Leu Val Asp Glu Val Arg Ser Ser 950 955 960 965 caa acc tca gac acc aat cca cag atg cag atc gct gaa gta caa ctt 3043 Gln Thr Ser Asp Thr Asn Pro Gln Met Gln Ile Ala Glu Val Gln Leu 970 975 980 gtt ggt tgg taaattacgc gtttgtgatt gac 3075 Val Gly Trp <210> 594 <211> 984 <212> PRT <213> Corynebacterium glutamicum <400> 594 Val Leu Gly Ala Val Leu Thr Ser Leu Val Ile Pro Val Leu Thr Arg 1 5 10 15 Ala Glu Lys Glu Asp Ala Asp Gly Gly Ser Gly Phe Phe Arg Arg Leu 20 25 30 Leu Thr Leu Ser Val Thr Leu Leu Gly Gly Val Thr Ile Leu Ser Ile 35 40 45 Ile Gly Ala Pro Leu Leu Thr Arg Met Met Leu Ser Ser Glu Gly Gln 50 55 60 Val Asn Val Val Met Ser Thr Ala Phe Ala Tyr Trp Leu Leu Pro Gln 65 70 75 80 Ile Phe Phe Tyr Gly Leu Phe Ala Leu Phe Met Ala Val Leu Asn Thr 85 90 95 Arg Glu Val Phe Lys Pro Gly Ala Trp Ala Pro Val Val Asn Asn Val 100 105 110 Ile Thr Leu Thr Val Leu Gly Val Tyr Met Val Leu Pro Ala Arg Leu 115 120 125 His Pro His Glu Gln Val Gly Ile Phe Asp Pro Gln Ile Ile Phe Leu 130 135 140 Gly Val Gly Thr Thr Leu Gly Val Val Ala Gln Cys Leu Ile Met Ile 145 150 155 160 Pro Tyr Leu Arg Arg Ala Gly Ile Asp Met Arg Pro Leu Trp Gly Ile 165 170 175 Asp Ala Arg Leu Lys Gln Phe Gly Gly Met Ala Met Ala Ile Ile Val 180 185 190 Tyr Val Ala Ile Ser Gln Phe Gly Tyr Ile Ile Thr Thr Arg Ile Ala 195 200 205 Ser Ile Ala Asp Asp Ala Ala Pro Phe Ile Tyr Gln Gln His Trp Met 210 215 220 Leu Leu Gln Val Pro Tyr Gly Ile Ile Gly Val Thr Leu Leu Thr Ala 225 230 235 240 Ile Met Pro Arg Leu Ser Arg Asn Ala Ala Asp Gly Asp Asp Arg Ala 245 250 255 Val Val Ser Asp Leu Gln Leu Gly Ser Lys Leu Thr Phe Ile Ala Leu 260 265 270 Ile Pro Ile Val Val Phe Phe Thr Ala Phe Gly Val Pro Ile Ala Asn 275 280 285 Gly Leu Phe Ala Tyr Gly Gln Phe Asp Ala Asn Ala Ala Asn Ile Leu 290 295 300 Gly Trp Thr Leu Ser Phe Ser Ala Phe Thr Leu Ile Pro Tyr Ala Leu 305 310 315 320 Val Leu Leu His Leu Arg Val Phe Tyr Ala Arg Glu Glu Val Trp Thr 325 330 335 Pro Thr Phe Ile Ile Ala Gly Ile Thr Ala Thr Lys Val Val Leu Ser 340 345 350 Leu Leu Ala Pro Leu Leu Ser Ser Ser Pro Glu Arg Val Val Val Leu 355 360 365 Leu Gly Ala Ala Asn Gly Phe Ser Phe Ile Thr Gly Ala Val Ile Gly 370 375 380 Ala Tyr Leu Leu Arg Asn Lys Leu Gly Leu Leu Gly Met Arg Ser Leu 385 390 395 400 Ala Lys Thr Ser Leu Trp Ala Leu Gly Ser Ala Ala Val Gly Ala Ala 405 410 415 Ala Ala Trp Ala Leu Gly Trp Leu Ile Gln Ala Val Val Gly Asp Phe 420 425 430 Leu Leu Gly Thr Leu Ser Ser Val Gly Tyr Leu Leu Asn Leu Ala Val 435 440 445 Leu Gly Val Phe Phe Ile Phe Val Thr Gly Ile Val Leu Ser Arg Ser 450 455 460 Gly Leu Pro Glu Val Gln Asn Leu Gly Gln Ala Leu Thr Arg Ile Pro 465 470 475 480 Gly Leu Ser Arg Phe Ile Arg Pro Asn Thr Lys Ile Ser Leu Asp Val 485 490 495 Gly Glu Val Ser Glu Gln Asp Phe Ser Thr Gln Leu Val Ala Pro Ser 500 505 510 Glu Phe Ala Ala Thr Pro Val Pro Pro Pro Met Ser Ala Gly Ile Val 515 520 525 Arg Gly Pro Arg Leu Val Pro Gly Ala Pro Val Gly Asp Gly Arg Phe 530 535 540 Arg Leu Leu Ala Asp His Gly Gly Val Gln Gly Ala Arg Phe Trp Gln 545 550 555 560 Ala Arg Glu Ile Ala Thr Gly Lys Glu Val Ala Leu Ile Phe Val Asp 565 570 575 Thr Ser Gly Asn Ala Pro Phe Ala Pro Leu Ser Ser Ala Ala Ala Ala 580 585 590 Gly Ile Ala Tyr Glu Val Gln Arg Arg Thr Lys Lys Leu Ala Ser Leu 595 600 605 Gly Ser Leu Ala Val Ala Pro Asn Ile His Ser Glu Ala Tyr Arg Asn 610 615 620 Gly Cys Leu Ile Val Ala Asp Trp Val Pro Gly Ser Ser Leu Ser Ala 625 630 635 640 Val Ala Glu Ser Gly Ala Asp Pro Arg Ala Ala Ala Phe Ala Leu Ala 645 650 655 Glu Leu Thr Glu Thr Ile Gly Glu Ala His Glu Met Gly Ile Pro Ala 660 665 670 Gly Leu Asp Asn Lys Cys Arg Ile Arg Ile Asn Thr Asp Gly His Ala 675 680 685 Val Leu Ala Leu Pro Ala Ile Leu Pro Asp Ala Ser Glu Leu Arg Asp 690 695 700 Ala Lys Ser Leu Ala Ser Ala Ala Glu Met Leu Ile Asp Ala Thr Leu 705 710 715 720 Ala Pro Ser Asp Val Lys Ala Met Val Thr Glu Ala Gln Gly Leu Ala 725 730 735 Thr Glu Asp Asn Pro Asp Tyr Ala Ser Leu Ala Met Ala Met Arg Thr 740 745 750 Cys Gly Leu Phe Thr Glu Glu Pro Thr His Leu Val Val Lys Lys Glu 755 760 765 Lys Thr Pro Lys Pro Ala Thr Arg Asp Gly Phe Gly Ala Ser Asp Tyr 770 775 780 Thr Val Lys Gly Met Ala Ala Ile Ala Ala Val Val Ile Ile Leu Val 785 790 795 800 Ser Leu Val Ala Ala Gly Thr Ala Phe Leu Thr Ser Phe Phe Gly Ser 805 810 815 Ser Thr Asn Glu Gln Ser Pro Leu Ala Ser Val Glu Ala Thr Thr Ser 820 825 830 Ala Thr Pro Glu Pro Val Gly Pro Pro Val Tyr Leu Asp Leu Asp Gln 835 840 845 Ala Arg Thr Trp Asp Asp Gly Ala Gly Thr Asp Val Thr Asp Val Thr 850 855 860 Asp Gly Asn Thr Ser Thr Ala Trp Thr Ser Thr Gly Gly Asp Gly Leu 865 870 875 880 Leu Val Asp Leu Ser Thr Pro Ala Arg Leu Asp Arg Val Ile Leu Thr 885 890 895 Thr Gly Thr Gly Ser Asp Ser Asn Val Thr Ser Thr Val Lys Ile Tyr 900 905 910 Ala Phe Asn Asp Ala Ser Pro His Ser Leu Ser Glu Gly Ile Glu Ile 915 920 925 Gly Thr Val Asp Tyr Ser Gly Arg Ser Leu Ser His Ser Ile Arg Asp 930 935 940 Ser Ser Lys Leu Pro Gly Gln Val Glu Ser Val Val Ile Leu Val Asp 945 950 955 960 Glu Val Arg Ser Ser Gln Thr Ser Asp Thr Asn Pro Gln Met Gln Ile 965 970 975 Ala Glu Val Gln Leu Val Gly Trp 980 <210> 595 <211> 915 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(892) <223> RXA01807 <400> 595 gctcaccgag ctggacacca agctccgcgc agtgcaggaa gaacacggcg agctggaaat 60 gcagtggctg gaactcggcg aggaaatcga gggctagttc atg ccg tcg gca ggc 115 Met Pro Ser Ala Gly 1 5 gag gag att tta gag cag cgc gca cag ctg gag ttt gat cag cgc cgc 163 Glu Glu Ile Leu Glu Gln Arg Ala Gln Leu Glu Phe Asp Gln Arg Arg 10 15 20 gcc gat gtg gtg atg atc ggc agc cag gtg gtt tat ggt tcc gtg ggg 211 Ala Asp Val Val Met Ile Gly Ser Gln Val Val Tyr Gly Ser Val Gly 25 30 35 ctc agt gct gcc att ccg gtg atg cac aac gaa ggc ctc cgc gtg gtc 259 Leu Ser Ala Ala Ile Pro Val Met His Asn Glu Gly Leu Arg Val Val 40 45 50 gct gtc ccc acc gtg gtg tta agt tcc atg ccg cgt tat gca agt tct 307 Ala Val Pro Thr Val Val Leu Ser Ser Met Pro Arg Tyr Ala Ser Ser 55 60 65 cac cgc cag ccg atg tcg gac caa tgg ctc gcc gac gcg ctg caa gac 355 His Arg Gln Pro Met Ser Asp Gln Trp Leu Ala Asp Ala Leu Gln Asp 70 75 80 85 ctg gtg gat ctg ggg att atc gat gag gtt tcc acc att tcc acc ggc 403 Leu Val Asp Leu Gly Ile Ile Asp Glu Val Ser Thr Ile Ser Thr Gly 90 95 100 tat ttt acc tcc gct tct cag gtg cgt gtg gtc gct gcg tgg ctg cag 451 Tyr Phe Thr Ser Ala Ser Gln Val Arg Val Val Ala Ala Trp Leu Gln 105 110 115 aaa atc cgc gaa acc cat ccg cat gtg cgc atc gtg gtg gat ccc atc 499 Lys Ile Arg Glu Thr His Pro His Val Arg Ile Val Val Asp Pro Ile 120 125 130 atg ggg gac agt gac gtg gga att tat gtc gcc gac gag atc gca acc 547 Met Gly Asp Ser Asp Val Gly Ile Tyr Val Ala Asp Glu Ile Ala Thr 135 140 145 gcc atc tgc cag gac tta tgc cct ctg gct acc gga atc att ccc aat 595 Ala Ile Cys Gln Asp Leu Cys Pro Leu Ala Thr Gly Ile Ile Pro Asn 150 155 160 165 gct ttc gag ctc tcc cac atg gtt ggc tcc ggc gat ccg cgc tcg ctg 643 Ala Phe Glu Leu Ser His Met Val Gly Ser Gly Asp Pro Arg Ser Leu 170 175 180 ctc ggc ccg ttt ggc gag tgg atc atc atc acc agc gcc act gaa act 691 Leu Gly Pro Phe Gly Glu Trp Ile Ile Ile Thr Ser Ala Thr Glu Thr 185 190 195 gtg ggc acc acc gtc acc cgc atc gtc acc cgt gac agc gtc cag gaa 739 Val Gly Thr Thr Val Thr Arg Ile Val Thr Arg Asp Ser Val Gln Glu 200 205 210 atc gcc tcc gcc acc gtc gat acc acg gcc aaa ggg gca ggc gac gtc 787 Ile Ala Ser Ala Thr Val Asp Thr Thr Ala Lys Gly Ala Gly Asp Val 215 220 225 tac gcc gca gca tta atc gcc gcc ctg cat aaa gat ttt tcg ctt atc 835 Tyr Ala Ala Ala Leu Ile Ala Ala Leu His Lys Asp Phe Ser Leu Ile 230 235 240 245 gac gcc gcc agc cac gca tcc aac acc gtc tgc gcc ggc ctg cag acc 883 Asp Ala Ala Ser His Ala Ser Asn Thr Val Cys Ala Gly Leu Gln Thr 250 255 260 aaa gcg ctt taggtttcgt ccgtctctga cag 915 Lys Ala Leu <210> 596 <211> 264 <212> PRT <213> Corynebacterium glutamicum <400> 596 Met Pro Ser Ala Gly Glu Glu Ile Leu Glu Gln Arg Ala Gln Leu Glu 1 5 10 15 Phe Asp Gln Arg Arg Ala Asp Val Val Met Ile Gly Ser Gln Val Val 20 25 30 Tyr Gly Ser Val Gly Leu Ser Ala Ala Ile Pro Val Met His Asn Glu 35 40 45 Gly Leu Arg Val Val Ala Val Pro Thr Val Val Leu Ser Ser Met Pro 50 55 60 Arg Tyr Ala Ser Ser His Arg Gln Pro Met Ser Asp Gln Trp Leu Ala 65 70 75 80 Asp Ala Leu Gln Asp Leu Val Asp Leu Gly Ile Ile Asp Glu Val Ser 85 90 95 Thr Ile Ser Thr Gly Tyr Phe Thr Ser Ala Ser Gln Val Arg Val Val 100 105 110 Ala Ala Trp Leu Gln Lys Ile Arg Glu Thr His Pro His Val Arg Ile 115 120 125 Val Val Asp Pro Ile Met Gly Asp Ser Asp Val Gly Ile Tyr Val Ala 130 135 140 Asp Glu Ile Ala Thr Ala Ile Cys Gln Asp Leu Cys Pro Leu Ala Thr 145 150 155 160 Gly Ile Ile Pro Asn Ala Phe Glu Leu Ser His Met Val Gly Ser Gly 165 170 175 Asp Pro Arg Ser Leu Leu Gly Pro Phe Gly Glu Trp Ile Ile Ile Thr 180 185 190 Ser Ala Thr Glu Thr Val Gly Thr Thr Val Thr Arg Ile Val Thr Arg 195 200 205 Asp Ser Val Gln Glu Ile Ala Ser Ala Thr Val Asp Thr Thr Ala Lys 210 215 220 Gly Ala Gly Asp Val Tyr Ala Ala Ala Leu Ile Ala Ala Leu His Lys 225 230 235 240 Asp Phe Ser Leu Ile Asp Ala Ala Ser His Ala Ser Asn Thr Val Cys 245 250 255 Ala Gly Leu Gln Thr Lys Ala Leu 260 <210> 597 <211> 1461 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1438) <223> RXN02754 <400> 597 attatgaagc catcggagtt ggtgtggcct acaagggtga tcatgcgtgg atagtggtgg 60 agttcactgt agctcccgct gattccgtag aatcaacaga gtg aat acc aat ccg 115 Val Asn Thr Asn Pro 1 5 tct gaa ttc tcc tca aac cgt tca aca gct ctc ctt act gat aaa tat 163 Ser Glu Phe Ser Ser Asn Arg Ser Thr Ala Leu Leu Thr Asp Lys Tyr 10 15 20 gag ctg acc atg ctt caa gca gcg ctc gct gat ggt tct gca gaa cgc 211 Glu Leu Thr Met Leu Gln Ala Ala Leu Ala Asp Gly Ser Ala Glu Arg 25 30 35 ccc tca acg ttt gag gtc ttt agc cgc cgc ctc ccc aac gag cgc cga 259 Pro Ser Thr Phe Glu Val Phe Ser Arg Arg Leu Pro Asn Glu Arg Arg 40 45 50 tac ggt gtc gtc gca gga aca gca cga gtg ctg aag gcg att cgt gac 307 Tyr Gly Val Val Ala Gly Thr Ala Arg Val Leu Lys Ala Ile Arg Asp 55 60 65 ttt gta ttc aca gag gaa caa ctc gcc gat ctt gac ttt tta gac gac 355 Phe Val Phe Thr Glu Glu Gln Leu Ala Asp Leu Asp Phe Leu Asp Asp 70 75 80 85 cgt acc ctg gaa tac ctc cgc aac tac cga ttc acc ggc caa gtt gat 403 Arg Thr Leu Glu Tyr Leu Arg Asn Tyr Arg Phe Thr Gly Gln Val Asp 90 95 100 ggc tac cgc gaa ggc gaa atc tac ttc ccg cag tcc cct ctt ctg act 451 Gly Tyr Arg Glu Gly Glu Ile Tyr Phe Pro Gln Ser Pro Leu Leu Thr 105 110 115 gtg cgt ggc acg ttt gca gaa tgc gtc atc cta gaa act gtc att ttg 499 Val Arg Gly Thr Phe Ala Glu Cys Val Ile Leu Glu Thr Val Ile Leu 120 125 130 tcc atc atg aat gca gat tct gcc gtc gct tcc gcc gct gcg cgc atg 547 Ser Ile Met Asn Ala Asp Ser Ala Val Ala Ser Ala Ala Ala Arg Met 135 140 145 gtc acc gca gct gat ggt cgc ccc atc atc gaa atg gga tcc agg cgc 595 Val Thr Ala Ala Asp Gly Arg Pro Ile Ile Glu Met Gly Ser Arg Arg 150 155 160 165 acc cac gaa tac tcg gca gtc acc gca tcc cgc gca gca tac ctc gct 643 Thr His Glu Tyr Ser Ala Val Thr Ala Ser Arg Ala Ala Tyr Leu Ala 170 175 180 gga ttc tcc acc acc tcc aac ctc gag gcg gcc tac cgc tac gga att 691 Gly Phe Ser Thr Thr Ser Asn Leu Glu Ala Ala Tyr Arg Tyr Gly Ile 185 190 195 cca gca tcc gga acc tcc gcc cac gca tgg act ttg ctg cac atc aac 739 Pro Ala Ser Gly Thr Ser Ala His Ala Trp Thr Leu Leu His Ile Asn 200 205 210 gat gac ggc acc ccc aac gaa gca gca gct ttc aaa gca cag gtt gaa 787 Asp Asp Gly Thr Pro Asn Glu Ala Ala Ala Phe Lys Ala Gln Val Glu 215 220 225 tcc ctc ggc gtg gac acc acc ttg ctg gta gat act tat gac atc acc 835 Ser Leu Gly Val Asp Thr Thr Leu Leu Val Asp Thr Tyr Asp Ile Thr 230 235 240 245 caa ggt gtg gcc acc gcc att gaa gtt gca ggt cca gac ctt ggt ggc 883 Gln Gly Val Ala Thr Ala Ile Glu Val Ala Gly Pro Asp Leu Gly Gly 250 255 260 gta cgt atc gac tcc ggc gac cta ggt gtg ctt gcc cga aag gtc cgc 931 Val Arg Ile Asp Ser Gly Asp Leu Gly Val Leu Ala Arg Lys Val Arg 265 270 275 aag cag ctc gac gat ctc aac gcc cac aac acc aag att gtg gtc tcc 979 Lys Gln Leu Asp Asp Leu Asn Ala His Asn Thr Lys Ile Val Val Ser 280 285 290 tcc gac ctg gat gaa ttc gcc atc gcg ggt ctt cgc ggc gaa cca gtt 1027 Ser Asp Leu Asp Glu Phe Ala Ile Ala Gly Leu Arg Gly Glu Pro Val 295 300 305 gac gtc ttt ggc gtt ggc acc tcc gtt gtc aca ggt tct ggc gca cca 1075 Asp Val Phe Gly Val Gly Thr Ser Val Val Thr Gly Ser Gly Ala Pro 310 315 320 325 acc gct ggc ctc gtg tac aag atc ggg gaa gtt gcc ggt cac cct gtg 1123 Thr Ala Gly Leu Val Tyr Lys Ile Gly Glu Val Ala Gly His Pro Val 330 335 340 gcc aag cgt tcc cga aac aag gaa agc tac ggt ggt ggc aag aag gct 1171 Ala Lys Arg Ser Arg Asn Lys Glu Ser Tyr Gly Gly Gly Lys Lys Ala 345 350 355 gtg cgc acc cac cgc aag tcc ggt acc gca atc gaa gaa atc gtc tac 1219 Val Arg Thr His Arg Lys Ser Gly Thr Ala Ile Glu Glu Ile Val Tyr 360 365 370 cca ttc aat gcc gaa gca cca gat act gga aag ctc gac act ttg agc 1267 Pro Phe Asn Ala Glu Ala Pro Asp Thr Gly Lys Leu Asp Thr Leu Ser 375 380 385 ctg acc atc cca ttg atg cgc gac ggt gaa atc gtt cca ggt ttg cct 1315 Leu Thr Ile Pro Leu Met Arg Asp Gly Glu Ile Val Pro Gly Leu Pro 390 395 400 405 act ttg gaa gat tcc cga gcg tat ttg gcc aag caa ttg gtc tct tta 1363 Thr Leu Glu Asp Ser Arg Ala Tyr Leu Ala Lys Gln Leu Val Ser Leu 410 415 420 cca tgg gaa ggc ctt gca ctg tct cgc gat gag cct gtt ttg cac act 1411 Pro Trp Glu Gly Leu Ala Leu Ser Arg Asp Glu Pro Val Leu His Thr 425 430 435 cgt ttc gtg ggt ttc ccg ccg gcc gct tagacaattc ggtctcacca 1458 Arg Phe Val Gly Phe Pro Pro Ala Ala 440 445 aac 1461 <210> 598 <211> 446 <212> PRT <213> Corynebacterium glutamicum <400> 598 Val Asn Thr Asn Pro Ser Glu Phe Ser Ser Asn Arg Ser Thr Ala Leu 1 5 10 15 Leu Thr Asp Lys Tyr Glu Leu Thr Met Leu Gln Ala Ala Leu Ala Asp 20 25 30 Gly Ser Ala Glu Arg Pro Ser Thr Phe Glu Val Phe Ser Arg Arg Leu 35 40 45 Pro Asn Glu Arg Arg Tyr Gly Val Val Ala Gly Thr Ala Arg Val Leu 50 55 60 Lys Ala Ile Arg Asp Phe Val Phe Thr Glu Glu Gln Leu Ala Asp Leu 65 70 75 80 Asp Phe Leu Asp Asp Arg Thr Leu Glu Tyr Leu Arg Asn Tyr Arg Phe 85 90 95 Thr Gly Gln Val Asp Gly Tyr Arg Glu Gly Glu Ile Tyr Phe Pro Gln 100 105 110 Ser Pro Leu Leu Thr Val Arg Gly Thr Phe Ala Glu Cys Val Ile Leu 115 120 125 Glu Thr Val Ile Leu Ser Ile Met Asn Ala Asp Ser Ala Val Ala Ser 130 135 140 Ala Ala Ala Arg Met Val Thr Ala Ala Asp Gly Arg Pro Ile Ile Glu 145 150 155 160 Met Gly Ser Arg Arg Thr His Glu Tyr Ser Ala Val Thr Ala Ser Arg 165 170 175 Ala Ala Tyr Leu Ala Gly Phe Ser Thr Thr Ser Asn Leu Glu Ala Ala 180 185 190 Tyr Arg Tyr Gly Ile Pro Ala Ser Gly Thr Ser Ala His Ala Trp Thr 195 200 205 Leu Leu His Ile Asn Asp Asp Gly Thr Pro Asn Glu Ala Ala Ala Phe 210 215 220 Lys Ala Gln Val Glu Ser Leu Gly Val Asp Thr Thr Leu Leu Val Asp 225 230 235 240 Thr Tyr Asp Ile Thr Gln Gly Val Ala Thr Ala Ile Glu Val Ala Gly 245 250 255 Pro Asp Leu Gly Gly Val Arg Ile Asp Ser Gly Asp Leu Gly Val Leu 260 265 270 Ala Arg Lys Val Arg Lys Gln Leu Asp Asp Leu Asn Ala His Asn Thr 275 280 285 Lys Ile Val Val Ser Ser Asp Leu Asp Glu Phe Ala Ile Ala Gly Leu 290 295 300 Arg Gly Glu Pro Val Asp Val Phe Gly Val Gly Thr Ser Val Val Thr 305 310 315 320 Gly Ser Gly Ala Pro Thr Ala Gly Leu Val Tyr Lys Ile Gly Glu Val 325 330 335 Ala Gly His Pro Val Ala Lys Arg Ser Arg Asn Lys Glu Ser Tyr Gly 340 345 350 Gly Gly Lys Lys Ala Val Arg Thr His Arg Lys Ser Gly Thr Ala Ile 355 360 365 Glu Glu Ile Val Tyr Pro Phe Asn Ala Glu Ala Pro Asp Thr Gly Lys 370 375 380 Leu Asp Thr Leu Ser Leu Thr Ile Pro Leu Met Arg Asp Gly Glu Ile 385 390 395 400 Val Pro Gly Leu Pro Thr Leu Glu Asp Ser Arg Ala Tyr Leu Ala Lys 405 410 415 Gln Leu Val Ser Leu Pro Trp Glu Gly Leu Ala Leu Ser Arg Asp Glu 420 425 430 Pro Val Leu His Thr Arg Phe Val Gly Phe Pro Pro Ala Ala 435 440 445 <210> 599 <211> 871 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(871) <223> FRXA02405 <400> 599 attatgaagc catcggagtt ggtgtggcct acaagggtga tcatgcgtgg atagtggtgg 60 agttcactgt agctcccgct gattccgtag aatcaacaga gtg aat acc aat ccg 115 Val Asn Thr Asn Pro 1 5 tct gaa ttc tcc tca aac cgt tca aca gct ctc ctt act gat aaa tat 163 Ser Glu Phe Ser Ser Asn Arg Ser Thr Ala Leu Leu Thr Asp Lys Tyr 10 15 20 gag ctg acc atg ctt caa gca gcg ctc gct gat ggt tct gca gaa cgc 211 Glu Leu Thr Met Leu Gln Ala Ala Leu Ala Asp Gly Ser Ala Glu Arg 25 30 35 ccc tca acg ttt gag gtc ttt agc cgc cgc ctc ccc aac gag cgc cga 259 Pro Ser Thr Phe Glu Val Phe Ser Arg Arg Leu Pro Asn Glu Arg Arg 40 45 50 tac ggt gtc gtc gca gga aca gca cga gtg ctg aag gcg att cgt gac 307 Tyr Gly Val Val Ala Gly Thr Ala Arg Val Leu Lys Ala Ile Arg Asp 55 60 65 ttt gta ttc aca gag gaa caa ctc gcc gat ctt gac ttt tta gac gac 355 Phe Val Phe Thr Glu Glu Gln Leu Ala Asp Leu Asp Phe Leu Asp Asp 70 75 80 85 cgt acc ctg gaa tac ctc cgc aac tac cga ttc acc ggc caa gtt gat 403 Arg Thr Leu Glu Tyr Leu Arg Asn Tyr Arg Phe Thr Gly Gln Val Asp 90 95 100 ggc tac cgc gaa ggc gaa atc tac ttc ccg cag tcc cct ctt ctg act 451 Gly Tyr Arg Glu Gly Glu Ile Tyr Phe Pro Gln Ser Pro Leu Leu Thr 105 110 115 gtg cgt ggc acg ttt gca gaa tgc gtc atc cta gaa act gtc att ttg 499 Val Arg Gly Thr Phe Ala Glu Cys Val Ile Leu Glu Thr Val Ile Leu 120 125 130 tcc atc atg aat gca gat tct gcc gtc gct tcc gcc gct gcg cgc atg 547 Ser Ile Met Asn Ala Asp Ser Ala Val Ala Ser Ala Ala Ala Arg Met 135 140 145 gtc acc gca gct gat ggt cgc ccc atc atc gaa atg gga tcc agg cgc 595 Val Thr Ala Ala Asp Gly Arg Pro Ile Ile Glu Met Gly Ser Arg Arg 150 155 160 165 acc cac gaa tac tcg gca gtc acc gca tcc cgc gca gca tac ctc gct 643 Thr His Glu Tyr Ser Ala Val Thr Ala Ser Arg Ala Ala Tyr Leu Ala 170 175 180 gga ttc tcc acc acc tcc aac ctc gag gcg gcc tac cgc tac gga att 691 Gly Phe Ser Thr Thr Ser Asn Leu Glu Ala Ala Tyr Arg Tyr Gly Ile 185 190 195 cca gca tcc gga acc tcc gcc cac gca tgg act ttg ctg cac atc aac 739 Pro Ala Ser Gly Thr Ser Ala His Ala Trp Thr Leu Leu His Ile Asn 200 205 210 gat gac ggc acc ccc aac gaa gca gca gct ttc aaa gca cag gtt gaa 787 Asp Asp Gly Thr Pro Asn Glu Ala Ala Ala Phe Lys Ala Gln Val Glu 215 220 225 tcc ctc ggc gtg gac acc acc ttg ctg gta gat act tat gac atc acc 835 Ser Leu Gly Val Asp Thr Thr Leu Leu Val Asp Thr Tyr Asp Ile Thr 230 235 240 245 caa ggt gtg gcc acc gcc att gaa gtt gca ggt cca 871 Gln Gly Val Ala Thr Ala Ile Glu Val Ala Gly Pro 250 255 <210> 600 <211> 257 <212> PRT <213> Corynebacterium glutamicum <400> 600 Val Asn Thr Asn Pro Ser Glu Phe Ser Ser Asn Arg Ser Thr Ala Leu 1 5 10 15 Leu Thr Asp Lys Tyr Glu Leu Thr Met Leu Gln Ala Ala Leu Ala Asp 20 25 30 Gly Ser Ala Glu Arg Pro Ser Thr Phe Glu Val Phe Ser Arg Arg Leu 35 40 45 Pro Asn Glu Arg Arg Tyr Gly Val Val Ala Gly Thr Ala Arg Val Leu 50 55 60 Lys Ala Ile Arg Asp Phe Val Phe Thr Glu Glu Gln Leu Ala Asp Leu 65 70 75 80 Asp Phe Leu Asp Asp Arg Thr Leu Glu Tyr Leu Arg Asn Tyr Arg Phe 85 90 95 Thr Gly Gln Val Asp Gly Tyr Arg Glu Gly Glu Ile Tyr Phe Pro Gln 100 105 110 Ser Pro Leu Leu Thr Val Arg Gly Thr Phe Ala Glu Cys Val Ile Leu 115 120 125 Glu Thr Val Ile Leu Ser Ile Met Asn Ala Asp Ser Ala Val Ala Ser 130 135 140 Ala Ala Ala Arg Met Val Thr Ala Ala Asp Gly Arg Pro Ile Ile Glu 145 150 155 160 Met Gly Ser Arg Arg Thr His Glu Tyr Ser Ala Val Thr Ala Ser Arg 165 170 175 Ala Ala Tyr Leu Ala Gly Phe Ser Thr Thr Ser Asn Leu Glu Ala Ala 180 185 190 Tyr Arg Tyr Gly Ile Pro Ala Ser Gly Thr Ser Ala His Ala Trp Thr 195 200 205 Leu Leu His Ile Asn Asp Asp Gly Thr Pro Asn Glu Ala Ala Ala Phe 210 215 220 Lys Ala Gln Val Glu Ser Leu Gly Val Asp Thr Thr Leu Leu Val Asp 225 230 235 240 Thr Tyr Asp Ile Thr Gln Gly Val Ala Thr Ala Ile Glu Val Ala Gly 245 250 255 Pro <210> 601 <211> 509 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(486) <223> FRXA02754 <400> 601 ccc aca aac acc aag att gtg gtc tcc tcc gac ctg gat gaa ttc gcc 48 Pro Thr Asn Thr Lys Ile Val Val Ser Ser Asp Leu Asp Glu Phe Ala 1 5 10 15 atc gcg ggt ctt cgc ggc gaa cca gtt gac gtc ttt ggc gtt ggc acc 96 Ile Ala Gly Leu Arg Gly Glu Pro Val Asp Val Phe Gly Val Gly Thr 20 25 30 tcc gtt gtc aca ggt tct ggc gca cca acc gct ggc ctc gtg tac aag 144 Ser Val Val Thr Gly Ser Gly Ala Pro Thr Ala Gly Leu Val Tyr Lys 35 40 45 atc ggg gaa gtt gcc ggt cac cct gtg gcc aag cgt tcc cga aac aag 192 Ile Gly Glu Val Ala Gly His Pro Val Ala Lys Arg Ser Arg Asn Lys 50 55 60 gaa agc tac ggt ggt ggc aag aag gct gtg cgc acc cac cgc aag tcc 240 Glu Ser Tyr Gly Gly Gly Lys Lys Ala Val Arg Thr His Arg Lys Ser 65 70 75 80 ggt acc gca atc gaa gaa atc gtc tac cca ttc aat gcc gaa gca cca 288 Gly Thr Ala Ile Glu Glu Ile Val Tyr Pro Phe Asn Ala Glu Ala Pro 85 90 95 gat act gga aag ctc gac act ttg agc ctg acc atc cca ttg atg cgc 336 Asp Thr Gly Lys Leu Asp Thr Leu Ser Leu Thr Ile Pro Leu Met Arg 100 105 110 gac ggt gaa atc gtt cca ggt ttg cct act ttg gaa gat tcc cga gcg 384 Asp Gly Glu Ile Val Pro Gly Leu Pro Thr Leu Glu Asp Ser Arg Ala 115 120 125 tat ttg gcc aag caa ttg gtc tct tta cca tgg gaa ggc ctt gca ctg 432 Tyr Leu Ala Lys Gln Leu Val Ser Leu Pro Trp Glu Gly Leu Ala Leu 130 135 140 tct cgc gat gag cct gtt ttg cac act cgt ttc gtg ggt ttc ccg ccg 480 Ser Arg Asp Glu Pro Val Leu His Thr Arg Phe Val Gly Phe Pro Pro 145 150 155 160 gcc gct tagacaattc ggtctcacca aac 509 Ala Ala <210> 602 <211> 162 <212> PRT <213> Corynebacterium glutamicum <400> 602 Pro Thr Asn Thr Lys Ile Val Val Ser Ser Asp Leu Asp Glu Phe Ala 1 5 10 15 Ile Ala Gly Leu Arg Gly Glu Pro Val Asp Val Phe Gly Val Gly Thr 20 25 30 Ser Val Val Thr Gly Ser Gly Ala Pro Thr Ala Gly Leu Val Tyr Lys 35 40 45 Ile Gly Glu Val Ala Gly His Pro Val Ala Lys Arg Ser Arg Asn Lys 50 55 60 Glu Ser Tyr Gly Gly Gly Lys Lys Ala Val Arg Thr His Arg Lys Ser 65 70 75 80 Gly Thr Ala Ile Glu Glu Ile Val Tyr Pro Phe Asn Ala Glu Ala Pro 85 90 95 Asp Thr Gly Lys Leu Asp Thr Leu Ser Leu Thr Ile Pro Leu Met Arg 100 105 110 Asp Gly Glu Ile Val Pro Gly Leu Pro Thr Leu Glu Asp Ser Arg Ala 115 120 125 Tyr Leu Ala Lys Gln Leu Val Ser Leu Pro Trp Glu Gly Leu Ala Leu 130 135 140 Ser Arg Asp Glu Pro Val Leu His Thr Arg Phe Val Gly Phe Pro Pro 145 150 155 160 Ala Ala <210> 603 <211> 960 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(937) <223> RXA02112 <400> 603 tgaatccgtg gcggcaccgg cgcgagtcgc tttggaaagg atgctatctg ttgttccagc 60 agctcctgtt actcctagct cctcgaagga tgcgtaattt atg act acc cat att 115 Met Thr Thr His Ile 1 5 gac cgc atc gtt ggc gca gcg tta tcc gag gat gcg cca tgg ggc gac 163 Asp Arg Ile Val Gly Ala Ala Leu Ser Glu Asp Ala Pro Trp Gly Asp 10 15 20 att acc tcc gac act ttt atc cca gga tcg gcg cag ctg agc gcc aag 211 Ile Thr Ser Asp Thr Phe Ile Pro Gly Ser Ala Gln Leu Ser Ala Lys 25 30 35 gtt gtt gcc cgg gag cca ggt gtg ttc agc ggg cag gcg ctt tta gac 259 Val Val Ala Arg Glu Pro Gly Val Phe Ser Gly Gln Ala Leu Leu Asp 40 45 50 gcc tcc ttc cgg ctc gtc gat cct agg ata aac gca tcc ctt aag gtg 307 Ala Ser Phe Arg Leu Val Asp Pro Arg Ile Asn Ala Ser Leu Lys Val 55 60 65 gct gat ggt gac agc ttt gaa acc ggg gac atc cta gga aca att acc 355 Ala Asp Gly Asp Ser Phe Glu Thr Gly Asp Ile Leu Gly Thr Ile Thr 70 75 80 85 ggc agt gct aga agc atc ctc cgt tca gag cgc att gct ctc aac ttc 403 Gly Ser Ala Arg Ser Ile Leu Arg Ser Glu Arg Ile Ala Leu Asn Phe 90 95 100 att cag agg acg tcc ggc atc gct aca ttg aca tcg tgc tat gtt gca 451 Ile Gln Arg Thr Ser Gly Ile Ala Thr Leu Thr Ser Cys Tyr Val Ala 105 110 115 gag gtt aaa ggc acc aaa gcc cgc att gtt gat acc cgg aaa acc aca 499 Glu Val Lys Gly Thr Lys Ala Arg Ile Val Asp Thr Arg Lys Thr Thr 120 125 130 ccc ggc ctg cgc atc att gaa cgc caa gct gtc cgt gac ggt ggc gga 547 Pro Gly Leu Arg Ile Ile Glu Arg Gln Ala Val Arg Asp Gly Gly Gly 135 140 145 ttt aat cac cga gcc acc ttg tcc gat gct gtc atg gtg aaa gat aac 595 Phe Asn His Arg Ala Thr Leu Ser Asp Ala Val Met Val Lys Asp Asn 150 155 160 165 cat ctc gca gcc atc gca tcc cag ggg ctc agc atc act gaa gcg ctg 643 His Leu Ala Ala Ile Ala Ser Gln Gly Leu Ser Ile Thr Glu Ala Leu 170 175 180 tcg aat atg aaa gct aaa ctc ccc cac acc acc cat gtg gaa gtc gaa 691 Ser Asn Met Lys Ala Lys Leu Pro His Thr Thr His Val Glu Val Glu 185 190 195 gtt gat cat ata gag cag atc gaa cca gtt ctt gct gct ggt gtg gac 739 Val Asp His Ile Glu Gln Ile Glu Pro Val Leu Ala Ala Gly Val Asp 200 205 210 acc atc atg ttg gat aat ttc acc att gat cag ctc atc gaa ggc gtt 787 Thr Ile Met Leu Asp Asn Phe Thr Ile Asp Gln Leu Ile Glu Gly Val 215 220 225 gat ctc att ggt gga cgt gca ctg gtg gaa gca tct ggc gga gtc aac 835 Asp Leu Ile Gly Gly Arg Ala Leu Val Glu Ala Ser Gly Gly Val Asn 230 235 240 245 ctc aac acc gcg gga aag att gca tca acc ggt gtc gac gtc att tcc 883 Leu Asn Thr Ala Gly Lys Ile Ala Ser Thr Gly Val Asp Val Ile Ser 250 255 260 gtt gga gcg ctt acc cat tct gtg cat gca ctt gac cta gga ctc gat 931 Val Gly Ala Leu Thr His Ser Val His Ala Leu Asp Leu Gly Leu Asp 265 270 275 att ttc taatgctcta ccttgataat gca 960 Ile Phe <210> 604 <211> 279 <212> PRT <213> Corynebacterium glutamicum <400> 604 Met Thr Thr His Ile Asp Arg Ile Val Gly Ala Ala Leu Ser Glu Asp 1 5 10 15 Ala Pro Trp Gly Asp Ile Thr Ser Asp Thr Phe Ile Pro Gly Ser Ala 20 25 30 Gln Leu Ser Ala Lys Val Val Ala Arg Glu Pro Gly Val Phe Ser Gly 35 40 45 Gln Ala Leu Leu Asp Ala Ser Phe Arg Leu Val Asp Pro Arg Ile Asn 50 55 60 Ala Ser Leu Lys Val Ala Asp Gly Asp Ser Phe Glu Thr Gly Asp Ile 65 70 75 80 Leu Gly Thr Ile Thr Gly Ser Ala Arg Ser Ile Leu Arg Ser Glu Arg 85 90 95 Ile Ala Leu Asn Phe Ile Gln Arg Thr Ser Gly Ile Ala Thr Leu Thr 100 105 110 Ser Cys Tyr Val Ala Glu Val Lys Gly Thr Lys Ala Arg Ile Val Asp 115 120 125 Thr Arg Lys Thr Thr Pro Gly Leu Arg Ile Ile Glu Arg Gln Ala Val 130 135 140 Arg Asp Gly Gly Gly Phe Asn His Arg Ala Thr Leu Ser Asp Ala Val 145 150 155 160 Met Val Lys Asp Asn His Leu Ala Ala Ile Ala Ser Gln Gly Leu Ser 165 170 175 Ile Thr Glu Ala Leu Ser Asn Met Lys Ala Lys Leu Pro His Thr Thr 180 185 190 His Val Glu Val Glu Val Asp His Ile Glu Gln Ile Glu Pro Val Leu 195 200 205 Ala Ala Gly Val Asp Thr Ile Met Leu Asp Asn Phe Thr Ile Asp Gln 210 215 220 Leu Ile Glu Gly Val Asp Leu Ile Gly Gly Arg Ala Leu Val Glu Ala 225 230 235 240 Ser Gly Gly Val Asn Leu Asn Thr Ala Gly Lys Ile Ala Ser Thr Gly 245 250 255 Val Asp Val Ile Ser Val Gly Ala Leu Thr His Ser Val His Ala Leu 260 265 270 Asp Leu Gly Leu Asp Ile Phe 275 <210> 605 <211> 1407 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1384) <223> RXA02111 <400> 605 gcttgcggga acaccgcacc gcccacccaa actgttcaga ttccaaagat aaattctgac 60 gctcattcca gcccaccgtt tagaagaaaa gaccccaatc atg acc acc tca atc 115 Met Thr Thr Ser Ile 1 5 acc cca tct gtc aac ctt gca ttg aaa aat gcc aat agc tgc aac agt 163 Thr Pro Ser Val Asn Leu Ala Leu Lys Asn Ala Asn Ser Cys Asn Ser 10 15 20 gaa ctc aaa gac gga ccc tgg ttc ctc gac cag ccc gga atg ccg gat 211 Glu Leu Lys Asp Gly Pro Trp Phe Leu Asp Gln Pro Gly Met Pro Asp 25 30 35 gtc tac ggc ccc ggc gcg tca caa aac gat ccg atc cct gcg cat gct 259 Val Tyr Gly Pro Gly Ala Ser Gln Asn Asp Pro Ile Pro Ala His Ala 40 45 50 ccg cgc cag cag gtt ctc ccc gag gag tac cag cgc gca agt gat gac 307 Pro Arg Gln Gln Val Leu Pro Glu Glu Tyr Gln Arg Ala Ser Asp Asp 55 60 65 gaa ctg cat cgt agg atc cgg gaa gcg aaa gac acc ctg ggt gac aaa 355 Glu Leu His Arg Arg Ile Arg Glu Ala Lys Asp Thr Leu Gly Asp Lys 70 75 80 85 gtg gtt atc cta gga cac ttc tac cag cgc gat gaa gtt atc caa cac 403 Val Val Ile Leu Gly His Phe Tyr Gln Arg Asp Glu Val Ile Gln His 90 95 100 gca gat ttt gtt ggt gac tct ttc caa ctt gcc cgc gct gcc aaa acc 451 Ala Asp Phe Val Gly Asp Ser Phe Gln Leu Ala Arg Ala Ala Lys Thr 105 110 115 cga ccc gag gcg gaa gcg att gtg ttc tgc ggt gtg cac ttc atg gct 499 Arg Pro Glu Ala Glu Ala Ile Val Phe Cys Gly Val His Phe Met Ala 120 125 130 gaa acc gct gat ctg tta tcc acg gat gaa caa tca gtg atc ctc ccc 547 Glu Thr Ala Asp Leu Leu Ser Thr Asp Glu Gln Ser Val Ile Leu Pro 135 140 145 aac ctt gcc gca ggt tgc tcc atg gca gac atg gct gac ctt gat tcc 595 Asn Leu Ala Ala Gly Cys Ser Met Ala Asp Met Ala Asp Leu Asp Ser 150 155 160 165 gtc gaa gac tgc tgg gag caa ctc acc tca att tat ggc gat gac acc 643 Val Glu Asp Cys Trp Glu Gln Leu Thr Ser Ile Tyr Gly Asp Asp Thr 170 175 180 ctg atc cct gtg acc tac atg aat tcc tct gca gcg ctc aaa ggt ttc 691 Leu Ile Pro Val Thr Tyr Met Asn Ser Ser Ala Ala Leu Lys Gly Phe 185 190 195 gtg ggt gag cac ggc gga att gta tgc acc tcc tca aat gca cgt tcc 739 Val Gly Glu His Gly Gly Ile Val Cys Thr Ser Ser Asn Ala Arg Ser 200 205 210 gta ttg gag tgg gcg ttt gaa cgc ggc caa cga gtc ctg ttc ttc ccc 787 Val Leu Glu Trp Ala Phe Glu Arg Gly Gln Arg Val Leu Phe Phe Pro 215 220 225 gat cag cac ttg ggt cga aac acc gcg aaa gcc atg ggc att ggg atc 835 Asp Gln His Leu Gly Arg Asn Thr Ala Lys Ala Met Gly Ile Gly Ile 230 235 240 245 gat caa atg ccc ctg tgg aat ccc aac aaa cca ctg ggt ggc aac acc 883 Asp Gln Met Pro Leu Trp Asn Pro Asn Lys Pro Leu Gly Gly Asn Thr 250 255 260 gtt tcc gag cta gaa aac gca aag gta ctg ctc tgg cat ggt ttc tgc 931 Val Ser Glu Leu Glu Asn Ala Lys Val Leu Leu Trp His Gly Phe Cys 265 270 275 tct gta cac aag cgc ttt act gtc gag cag atc aac aaa gcc cgc gcc 979 Ser Val His Lys Arg Phe Thr Val Glu Gln Ile Asn Lys Ala Arg Ala 280 285 290 gag tac ccc gac gtt cac gtc atc gtg cac cct gaa tcc ccc atg cca 1027 Glu Tyr Pro Asp Val His Val Ile Val His Pro Glu Ser Pro Met Pro 295 300 305 gtt gtt gac gcc gcc gac tca tcc gga tcc act gac ttc att gtg aaa 1075 Val Val Asp Ala Ala Asp Ser Ser Gly Ser Thr Asp Phe Ile Val Lys 310 315 320 325 gcc att caa gca gca ccg gca gga tct acc ttt gcg atc ggc acc gaa 1123 Ala Ile Gln Ala Ala Pro Ala Gly Ser Thr Phe Ala Ile Gly Thr Glu 330 335 340 atc aac ttg gtt cag cgc ctg gca gcc cag tac ccg cag cac acc atc 1171 Ile Asn Leu Val Gln Arg Leu Ala Ala Gln Tyr Pro Gln His Thr Ile 345 350 355 ttc tgc ctc gac cct gtc atc tgc cca tgc tcc acc atg tat cgc att 1219 Phe Cys Leu Asp Pro Val Ile Cys Pro Cys Ser Thr Met Tyr Arg Ile 360 365 370 cac cct ggt tac ctg gcc tgg gca ctt gag gag ttg gtg gct gga aac 1267 His Pro Gly Tyr Leu Ala Trp Ala Leu Glu Glu Leu Val Ala Gly Asn 375 380 385 gtg att aac cag att tct gtc tct gaa tcc gtg gcg gca ccg gcg cga 1315 Val Ile Asn Gln Ile Ser Val Ser Glu Ser Val Ala Ala Pro Ala Arg 390 395 400 405 gtc gct ttg gaa agg atg cta tct gtt gtt cca gca gct cct gtt act 1363 Val Ala Leu Glu Arg Met Leu Ser Val Val Pro Ala Ala Pro Val Thr 410 415 420 cct agc tcc tcg aag gat gcg taatttatga ctacccatat tga 1407 Pro Ser Ser Ser Lys Asp Ala 425 <210> 606 <211> 428 <212> PRT <213> Corynebacterium glutamicum <400> 606 Met Thr Thr Ser Ile Thr Pro Ser Val Asn Leu Ala Leu Lys Asn Ala 1 5 10 15 Asn Ser Cys Asn Ser Glu Leu Lys Asp Gly Pro Trp Phe Leu Asp Gln 20 25 30 Pro Gly Met Pro Asp Val Tyr Gly Pro Gly Ala Ser Gln Asn Asp Pro 35 40 45 Ile Pro Ala His Ala Pro Arg Gln Gln Val Leu Pro Glu Glu Tyr Gln 50 55 60 Arg Ala Ser Asp Asp Glu Leu His Arg Arg Ile Arg Glu Ala Lys Asp 65 70 75 80 Thr Leu Gly Asp Lys Val Val Ile Leu Gly His Phe Tyr Gln Arg Asp 85 90 95 Glu Val Ile Gln His Ala Asp Phe Val Gly Asp Ser Phe Gln Leu Ala 100 105 110 Arg Ala Ala Lys Thr Arg Pro Glu Ala Glu Ala Ile Val Phe Cys Gly 115 120 125 Val His Phe Met Ala Glu Thr Ala Asp Leu Leu Ser Thr Asp Glu Gln 130 135 140 Ser Val Ile Leu Pro Asn Leu Ala Ala Gly Cys Ser Met Ala Asp Met 145 150 155 160 Ala Asp Leu Asp Ser Val Glu Asp Cys Trp Glu Gln Leu Thr Ser Ile 165 170 175 Tyr Gly Asp Asp Thr Leu Ile Pro Val Thr Tyr Met Asn Ser Ser Ala 180 185 190 Ala Leu Lys Gly Phe Val Gly Glu His Gly Gly Ile Val Cys Thr Ser 195 200 205 Ser Asn Ala Arg Ser Val Leu Glu Trp Ala Phe Glu Arg Gly Gln Arg 210 215 220 Val Leu Phe Phe Pro Asp Gln His Leu Gly Arg Asn Thr Ala Lys Ala 225 230 235 240 Met Gly Ile Gly Ile Asp Gln Met Pro Leu Trp Asn Pro Asn Lys Pro 245 250 255 Leu Gly Gly Asn Thr Val Ser Glu Leu Glu Asn Ala Lys Val Leu Leu 260 265 270 Trp His Gly Phe Cys Ser Val His Lys Arg Phe Thr Val Glu Gln Ile 275 280 285 Asn Lys Ala Arg Ala Glu Tyr Pro Asp Val His Val Ile Val His Pro 290 295 300 Glu Ser Pro Met Pro Val Val Asp Ala Ala Asp Ser Ser Gly Ser Thr 305 310 315 320 Asp Phe Ile Val Lys Ala Ile Gln Ala Ala Pro Ala Gly Ser Thr Phe 325 330 335 Ala Ile Gly Thr Glu Ile Asn Leu Val Gln Arg Leu Ala Ala Gln Tyr 340 345 350 Pro Gln His Thr Ile Phe Cys Leu Asp Pro Val Ile Cys Pro Cys Ser 355 360 365 Thr Met Tyr Arg Ile His Pro Gly Tyr Leu Ala Trp Ala Leu Glu Glu 370 375 380 Leu Val Ala Gly Asn Val Ile Asn Gln Ile Ser Val Ser Glu Ser Val 385 390 395 400 Ala Ala Pro Ala Arg Val Ala Leu Glu Arg Met Leu Ser Val Val Pro 405 410 415 Ala Ala Pro Val Thr Pro Ser Ser Ser Lys Asp Ala 420 425 <210> 607 <211> 954 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(931) <223> RXA01073 <400> 607 taaccgactc cagcactaaa ctccaaaccc ttggcccgca ccgccaaagt ttagcgcgcc 60 ccaagacacc accgcgccat gtttgcctag gattaggtac atg aca aac act caa 115 Met Thr Asn Thr Gln 1 5 acc gag atc att aat gaa cta aag gtg agc cca gca atc gac gtg gcc 163 Thr Glu Ile Ile Asn Glu Leu Lys Val Ser Pro Ala Ile Asp Val Ala 10 15 20 aag gaa gtt gaa ttc cgt gtg cag ttc ctc gtc gat tac ctg cgg gct 211 Lys Glu Val Glu Phe Arg Val Gln Phe Leu Val Asp Tyr Leu Arg Ala 25 30 35 tcc cat aca aaa ggc ttt gtt ctt ggt att tca ggt ggc cag gat tcc 259 Ser His Thr Lys Gly Phe Val Leu Gly Ile Ser Gly Gly Gln Asp Ser 40 45 50 act ctt gcg gga cga ctc acg cag ctg gca gta gag cgc att cgt gcg 307 Thr Leu Ala Gly Arg Leu Thr Gln Leu Ala Val Glu Arg Ile Arg Ala 55 60 65 gaa gaa aac agc acg gat tat gtc ttc tac gca gtt cgc ctc ccc tac 355 Glu Glu Asn Ser Thr Asp Tyr Val Phe Tyr Ala Val Arg Leu Pro Tyr 70 75 80 85 gcg atc cag gca gat gag gac gat gcg caa gtt gca ttg gaa ttc atc 403 Ala Ile Gln Ala Asp Glu Asp Asp Ala Gln Val Ala Leu Glu Phe Ile 90 95 100 gca cct gac aag agc gtg acc gtc aac gtt aaa gac gca acg gac gcc 451 Ala Pro Asp Lys Ser Val Thr Val Asn Val Lys Asp Ala Thr Asp Ala 105 110 115 acc gaa gca act gtt gca gct gct ttg gaa ctt cct gag ctg acc gac 499 Thr Glu Ala Thr Val Ala Ala Ala Leu Glu Leu Pro Glu Leu Thr Asp 120 125 130 ttc aat cgg ggc aat att aaa gct cgc caa cgc atg gtt gcc cag tac 547 Phe Asn Arg Gly Asn Ile Lys Ala Arg Gln Arg Met Val Ala Gln Tyr 135 140 145 gca atc gca ggc cag ttg ggc ttg ctg gtt att ggc act gat cac gcg 595 Ala Ile Ala Gly Gln Leu Gly Leu Leu Val Ile Gly Thr Asp His Ala 150 155 160 165 gct gaa aac gtc acg ggg ttc ttc acc aaa ttc ggt gat ggc gca gct 643 Ala Glu Asn Val Thr Gly Phe Phe Thr Lys Phe Gly Asp Gly Ala Ala 170 175 180 gac ctg ctt cct ttg gca ggt ttg agc aag cgt caa gga gct gcc att 691 Asp Leu Leu Pro Leu Ala Gly Leu Ser Lys Arg Gln Gly Ala Ala Ile 185 190 195 ctg gag cac ctg ggt gca cct tca agc acg tgg acc aag gtt cct acc 739 Leu Glu His Leu Gly Ala Pro Ser Ser Thr Trp Thr Lys Val Pro Thr 200 205 210 gct gat ttg gaa gag gat cgc cca gcg ttg cca gat gag gaa gca ctt 787 Ala Asp Leu Glu Glu Asp Arg Pro Ala Leu Pro Asp Glu Glu Ala Leu 215 220 225 ggt gtg tcg tat gcg gac atc gat aat tac ctg gaa aac aag ccc gat 835 Gly Val Ser Tyr Ala Asp Ile Asp Asn Tyr Leu Glu Asn Lys Pro Asp 230 235 240 245 gtc agt gaa aaa gcc cag cag cgc att gag cac ctg tgg aag gtg ggc 883 Val Ser Glu Lys Ala Gln Gln Arg Ile Glu His Leu Trp Lys Val Gly 250 255 260 cag cac aag cgc cac ctc cct gct acc ccg cag gaa aat tgg tgg cgt 931 Gln His Lys Arg His Leu Pro Ala Thr Pro Gln Glu Asn Trp Trp Arg 265 270 275 taatccaaca gtttgagtgt cgc 954 <210> 608 <211> 277 <212> PRT <213> Corynebacterium glutamicum <400> 608 Met Thr Asn Thr Gln Thr Glu Ile Ile Asn Glu Leu Lys Val Ser Pro 1 5 10 15 Ala Ile Asp Val Ala Lys Glu Val Glu Phe Arg Val Gln Phe Leu Val 20 25 30 Asp Tyr Leu Arg Ala Ser His Thr Lys Gly Phe Val Leu Gly Ile Ser 35 40 45 Gly Gly Gln Asp Ser Thr Leu Ala Gly Arg Leu Thr Gln Leu Ala Val 50 55 60 Glu Arg Ile Arg Ala Glu Glu Asn Ser Thr Asp Tyr Val Phe Tyr Ala 65 70 75 80 Val Arg Leu Pro Tyr Ala Ile Gln Ala Asp Glu Asp Asp Ala Gln Val 85 90 95 Ala Leu Glu Phe Ile Ala Pro Asp Lys Ser Val Thr Val Asn Val Lys 100 105 110 Asp Ala Thr Asp Ala Thr Glu Ala Thr Val Ala Ala Ala Leu Glu Leu 115 120 125 Pro Glu Leu Thr Asp Phe Asn Arg Gly Asn Ile Lys Ala Arg Gln Arg 130 135 140 Met Val Ala Gln Tyr Ala Ile Ala Gly Gln Leu Gly Leu Leu Val Ile 145 150 155 160 Gly Thr Asp His Ala Ala Glu Asn Val Thr Gly Phe Phe Thr Lys Phe 165 170 175 Gly Asp Gly Ala Ala Asp Leu Leu Pro Leu Ala Gly Leu Ser Lys Arg 180 185 190 Gln Gly Ala Ala Ile Leu Glu His Leu Gly Ala Pro Ser Ser Thr Trp 195 200 205 Thr Lys Val Pro Thr Ala Asp Leu Glu Glu Asp Arg Pro Ala Leu Pro 210 215 220 Asp Glu Glu Ala Leu Gly Val Ser Tyr Ala Asp Ile Asp Asn Tyr Leu 225 230 235 240 Glu Asn Lys Pro Asp Val Ser Glu Lys Ala Gln Gln Arg Ile Glu His 245 250 255 Leu Trp Lys Val Gly Gln His Lys Arg His Leu Pro Ala Thr Pro Gln 260 265 270 Glu Asn Trp Trp Arg 275 <210> 609 <211> 1461 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1438) <223> RXN02754 <400> 609 attatgaagc catcggagtt ggtgtggcct acaagggtga tcatgcgtgg atagtggtgg 60 agttcactgt agctcccgct gattccgtag aatcaacaga gtg aat acc aat ccg 115 Val Asn Thr Asn Pro 1 5 tct gaa ttc tcc tca aac cgt tca aca gct ctc ctt act gat aaa tat 163 Ser Glu Phe Ser Ser Asn Arg Ser Thr Ala Leu Leu Thr Asp Lys Tyr 10 15 20 gag ctg acc atg ctt caa gca gcg ctc gct gat ggt tct gca gaa cgc 211 Glu Leu Thr Met Leu Gln Ala Ala Leu Ala Asp Gly Ser Ala Glu Arg 25 30 35 ccc tca acg ttt gag gtc ttt agc cgc cgc ctc ccc aac gag cgc cga 259 Pro Ser Thr Phe Glu Val Phe Ser Arg Arg Leu Pro Asn Glu Arg Arg 40 45 50 tac ggt gtc gtc gca gga aca gca cga gtg ctg aag gcg att cgt gac 307 Tyr Gly Val Val Ala Gly Thr Ala Arg Val Leu Lys Ala Ile Arg Asp 55 60 65 ttt gta ttc aca gag gaa caa ctc gcc gat ctt gac ttt tta gac gac 355 Phe Val Phe Thr Glu Glu Gln Leu Ala Asp Leu Asp Phe Leu Asp Asp 70 75 80 85 cgt acc ctg gaa tac ctc cgc aac tac cga ttc acc ggc caa gtt gat 403 Arg Thr Leu Glu Tyr Leu Arg Asn Tyr Arg Phe Thr Gly Gln Val Asp 90 95 100 ggc tac cgc gaa ggc gaa atc tac ttc ccg cag tcc cct ctt ctg act 451 Gly Tyr Arg Glu Gly Glu Ile Tyr Phe Pro Gln Ser Pro Leu Leu Thr 105 110 115 gtg cgt ggc acg ttt gca gaa tgc gtc atc cta gaa act gtc att ttg 499 Val Arg Gly Thr Phe Ala Glu Cys Val Ile Leu Glu Thr Val Ile Leu 120 125 130 tcc atc atg aat gca gat tct gcc gtc gct tcc gcc gct gcg cgc atg 547 Ser Ile Met Asn Ala Asp Ser Ala Val Ala Ser Ala Ala Ala Arg Met 135 140 145 gtc acc gca gct gat ggt cgc ccc atc atc gaa atg gga tcc agg cgc 595 Val Thr Ala Ala Asp Gly Arg Pro Ile Ile Glu Met Gly Ser Arg Arg 150 155 160 165 acc cac gaa tac tcg gca gtc acc gca tcc cgc gca gca tac ctc gct 643 Thr His Glu Tyr Ser Ala Val Thr Ala Ser Arg Ala Ala Tyr Leu Ala 170 175 180 gga ttc tcc acc acc tcc aac ctc gag gcg gcc tac cgc tac gga att 691 Gly Phe Ser Thr Thr Ser Asn Leu Glu Ala Ala Tyr Arg Tyr Gly Ile 185 190 195 cca gca tcc gga acc tcc gcc cac gca tgg act ttg ctg cac atc aac 739 Pro Ala Ser Gly Thr Ser Ala His Ala Trp Thr Leu Leu His Ile Asn 200 205 210 gat gac ggc acc ccc aac gaa gca gca gct ttc aaa gca cag gtt gaa 787 Asp Asp Gly Thr Pro Asn Glu Ala Ala Ala Phe Lys Ala Gln Val Glu 215 220 225 tcc ctc ggc gtg gac acc acc ttg ctg gta gat act tat gac atc acc 835 Ser Leu Gly Val Asp Thr Thr Leu Leu Val Asp Thr Tyr Asp Ile Thr 230 235 240 245 caa ggt gtg gcc acc gcc att gaa gtt gca ggt cca gac ctt ggt ggc 883 Gln Gly Val Ala Thr Ala Ile Glu Val Ala Gly Pro Asp Leu Gly Gly 250 255 260 gta cgt atc gac tcc ggc gac cta ggt gtg ctt gcc cga aag gtc cgc 931 Val Arg Ile Asp Ser Gly Asp Leu Gly Val Leu Ala Arg Lys Val Arg 265 270 275 aag cag ctc gac gat ctc aac gcc cac aac acc aag att gtg gtc tcc 979 Lys Gln Leu Asp Asp Leu Asn Ala His Asn Thr Lys Ile Val Val Ser 280 285 290 tcc gac ctg gat gaa ttc gcc atc gcg ggt ctt cgc ggc gaa cca gtt 1027 Ser Asp Leu Asp Glu Phe Ala Ile Ala Gly Leu Arg Gly Glu Pro Val 295 300 305 gac gtc ttt ggc gtt ggc acc tcc gtt gtc aca ggt tct ggc gca cca 1075 Asp Val Phe Gly Val Gly Thr Ser Val Val Thr Gly Ser Gly Ala Pro 310 315 320 325 acc gct ggc ctc gtg tac aag atc ggg gaa gtt gcc ggt cac cct gtg 1123 Thr Ala Gly Leu Val Tyr Lys Ile Gly Glu Val Ala Gly His Pro Val 330 335 340 gcc aag cgt tcc cga aac aag gaa agc tac ggt ggt ggc aag aag gct 1171 Ala Lys Arg Ser Arg Asn Lys Glu Ser Tyr Gly Gly Gly Lys Lys Ala 345 350 355 gtg cgc acc cac cgc aag tcc ggt acc gca atc gaa gaa atc gtc tac 1219 Val Arg Thr His Arg Lys Ser Gly Thr Ala Ile Glu Glu Ile Val Tyr 360 365 370 cca ttc aat gcc gaa gca cca gat act gga aag ctc gac act ttg agc 1267 Pro Phe Asn Ala Glu Ala Pro Asp Thr Gly Lys Leu Asp Thr Leu Ser 375 380 385 ctg acc atc cca ttg atg cgc gac ggt gaa atc gtt cca ggt ttg cct 1315 Leu Thr Ile Pro Leu Met Arg Asp Gly Glu Ile Val Pro Gly Leu Pro 390 395 400 405 act ttg gaa gat tcc cga gcg tat ttg gcc aag caa ttg gtc tct tta 1363 Thr Leu Glu Asp Ser Arg Ala Tyr Leu Ala Lys Gln Leu Val Ser Leu 410 415 420 cca tgg gaa ggc ctt gca ctg tct cgc gat gag cct gtt ttg cac act 1411 Pro Trp Glu Gly Leu Ala Leu Ser Arg Asp Glu Pro Val Leu His Thr 425 430 435 cgt ttc gtg ggt ttc ccg ccg gcc gct tagacaattc ggtctcacca 1458 Arg Phe Val Gly Phe Pro Pro Ala Ala 440 445 aac 1461 <210> 610 <211> 446 <212> PRT <213> Corynebacterium glutamicum <400> 610 Val Asn Thr Asn Pro Ser Glu Phe Ser Ser Asn Arg Ser Thr Ala Leu 1 5 10 15 Leu Thr Asp Lys Tyr Glu Leu Thr Met Leu Gln Ala Ala Leu Ala Asp 20 25 30 Gly Ser Ala Glu Arg Pro Ser Thr Phe Glu Val Phe Ser Arg Arg Leu 35 40 45 Pro Asn Glu Arg Arg Tyr Gly Val Val Ala Gly Thr Ala Arg Val Leu 50 55 60 Lys Ala Ile Arg Asp Phe Val Phe Thr Glu Glu Gln Leu Ala Asp Leu 65 70 75 80 Asp Phe Leu Asp Asp Arg Thr Leu Glu Tyr Leu Arg Asn Tyr Arg Phe 85 90 95 Thr Gly Gln Val Asp Gly Tyr Arg Glu Gly Glu Ile Tyr Phe Pro Gln 100 105 110 Ser Pro Leu Leu Thr Val Arg Gly Thr Phe Ala Glu Cys Val Ile Leu 115 120 125 Glu Thr Val Ile Leu Ser Ile Met Asn Ala Asp Ser Ala Val Ala Ser 130 135 140 Ala Ala Ala Arg Met Val Thr Ala Ala Asp Gly Arg Pro Ile Ile Glu 145 150 155 160 Met Gly Ser Arg Arg Thr His Glu Tyr Ser Ala Val Thr Ala Ser Arg 165 170 175 Ala Ala Tyr Leu Ala Gly Phe Ser Thr Thr Ser Asn Leu Glu Ala Ala 180 185 190 Tyr Arg Tyr Gly Ile Pro Ala Ser Gly Thr Ser Ala His Ala Trp Thr 195 200 205 Leu Leu His Ile Asn Asp Asp Gly Thr Pro Asn Glu Ala Ala Ala Phe 210 215 220 Lys Ala Gln Val Glu Ser Leu Gly Val Asp Thr Thr Leu Leu Val Asp 225 230 235 240 Thr Tyr Asp Ile Thr Gln Gly Val Ala Thr Ala Ile Glu Val Ala Gly 245 250 255 Pro Asp Leu Gly Gly Val Arg Ile Asp Ser Gly Asp Leu Gly Val Leu 260 265 270 Ala Arg Lys Val Arg Lys Gln Leu Asp Asp Leu Asn Ala His Asn Thr 275 280 285 Lys Ile Val Val Ser Ser Asp Leu Asp Glu Phe Ala Ile Ala Gly Leu 290 295 300 Arg Gly Glu Pro Val Asp Val Phe Gly Val Gly Thr Ser Val Val Thr 305 310 315 320 Gly Ser Gly Ala Pro Thr Ala Gly Leu Val Tyr Lys Ile Gly Glu Val 325 330 335 Ala Gly His Pro Val Ala Lys Arg Ser Arg Asn Lys Glu Ser Tyr Gly 340 345 350 Gly Gly Lys Lys Ala Val Arg Thr His Arg Lys Ser Gly Thr Ala Ile 355 360 365 Glu Glu Ile Val Tyr Pro Phe Asn Ala Glu Ala Pro Asp Thr Gly Lys 370 375 380 Leu Asp Thr Leu Ser Leu Thr Ile Pro Leu Met Arg Asp Gly Glu Ile 385 390 395 400 Val Pro Gly Leu Pro Thr Leu Glu Asp Ser Arg Ala Tyr Leu Ala Lys 405 410 415 Gln Leu Val Ser Leu Pro Trp Glu Gly Leu Ala Leu Ser Arg Asp Glu 420 425 430 Pro Val Leu His Thr Arg Phe Val Gly Phe Pro Pro Ala Ala 435 440 445 <210> 611 <211> 531 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(508) <223> RXA02299 <400> 611 acgcgggggt tgttgccgga tcgaaatatt cctttccttg tcatctcacg ctatgatttc 60 taaaacttgc aggacaaccc ccataaggac accacaggac atg ctg cgc acc atc 115 Met Leu Arg Thr Ile 1 5 ctc gga agt aag att cac cga gcc act gtc act caa gct gat cta gat 163 Leu Gly Ser Lys Ile His Arg Ala Thr Val Thr Gln Ala Asp Leu Asp 10 15 20 tat gtt ggc tct gta acc atc gac gcc gac ctg gtt cac gcc gcc gga 211 Tyr Val Gly Ser Val Thr Ile Asp Ala Asp Leu Val His Ala Ala Gly 25 30 35 ttg atc gaa ggc gaa aaa gtt gcc atc gta gac atc acc aac ggc gct 259 Leu Ile Glu Gly Glu Lys Val Ala Ile Val Asp Ile Thr Asn Gly Ala 40 45 50 cgt ctg gaa act tat gtc att gtg ggc gac gcc gga acg ggc aat att 307 Arg Leu Glu Thr Tyr Val Ile Val Gly Asp Ala Gly Thr Gly Asn Ile 55 60 65 tgc atc aat ggt gcc gct gca cac ctt att aat cct ggc gat ctt gtg 355 Cys Ile Asn Gly Ala Ala Ala His Leu Ile Asn Pro Gly Asp Leu Val 70 75 80 85 atc atc atg agc tac ctt cag gca act gat gcg gaa gcc aag gcg tat 403 Ile Ile Met Ser Tyr Leu Gln Ala Thr Asp Ala Glu Ala Lys Ala Tyr 90 95 100 gag cca aag att gtg cac gtg gac gcc gac aac cgc atc gtt gcg ctc 451 Glu Pro Lys Ile Val His Val Asp Ala Asp Asn Arg Ile Val Ala Leu 105 110 115 ggc aac gat ctt gcg gaa gca cta cct gga tcc ggg ctt ttg acg tcg 499 Gly Asn Asp Leu Ala Glu Ala Leu Pro Gly Ser Gly Leu Leu Thr Ser 120 125 130 aga agc att tagcgtttta gctcgccaat att 531 Arg Ser Ile 135 <210> 612 <211> 136 <212> PRT <213> Corynebacterium glutamicum <400> 612 Met Leu Arg Thr Ile Leu Gly Ser Lys Ile His Arg Ala Thr Val Thr 1 5 10 15 Gln Ala Asp Leu Asp Tyr Val Gly Ser Val Thr Ile Asp Ala Asp Leu 20 25 30 Val His Ala Ala Gly Leu Ile Glu Gly Glu Lys Val Ala Ile Val Asp 35 40 45 Ile Thr Asn Gly Ala Arg Leu Glu Thr Tyr Val Ile Val Gly Asp Ala 50 55 60 Gly Thr Gly Asn Ile Cys Ile Asn Gly Ala Ala Ala His Leu Ile Asn 65 70 75 80 Pro Gly Asp Leu Val Ile Ile Met Ser Tyr Leu Gln Ala Thr Asp Ala 85 90 95 Glu Ala Lys Ala Tyr Glu Pro Lys Ile Val His Val Asp Ala Asp Asn 100 105 110 Arg Ile Val Ala Leu Gly Asn Asp Leu Ala Glu Ala Leu Pro Gly Ser 115 120 125 Gly Leu Leu Thr Ser Arg Ser Ile 130 135 <210> 613 <211> 960 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(937) <223> RXA01928 <400> 613 gcgagtacgc caccttgggc gattccttgc acgacgccgc gcaggcctac atcgccgata 60 tccacgcggg taccttccca ggcgaagcgg agtcctttta atg cag gta gca acc 115 Met Gln Val Ala Thr 1 5 aca aag cag gcg ctt atc gac gcc ctc ctc cac cac aaa tcc gtc ggg 163 Thr Lys Gln Ala Leu Ile Asp Ala Leu Leu His His Lys Ser Val Gly 10 15 20 ctc gtc ccc acc atg ggt gcg cta cac agc gga cac gcc tcg ttg gtt 211 Leu Val Pro Thr Met Gly Ala Leu His Ser Gly His Ala Ser Leu Val 25 30 35 aaa gca gca cgc gct gaa aac gac act gtt gta gcc agt att ttt gtc 259 Lys Ala Ala Arg Ala Glu Asn Asp Thr Val Val Ala Ser Ile Phe Val 40 45 50 aat ccc ctg cag ttt gaa gca ctc ggt gat tgc gat gat tac cgc aac 307 Asn Pro Leu Gln Phe Glu Ala Leu Gly Asp Cys Asp Asp Tyr Arg Asn 55 60 65 tat ccc cgc caa ctc gac gcc gat tta gca ctg ctt gaa gag gca ggt 355 Tyr Pro Arg Gln Leu Asp Ala Asp Leu Ala Leu Leu Glu Glu Ala Gly 70 75 80 85 gtg gat att gtg ttc gca ccc gat gtg gag gaa atg tac ccc ggt ggc 403 Val Asp Ile Val Phe Ala Pro Asp Val Glu Glu Met Tyr Pro Gly Gly 90 95 100 ttg cca cta gtg tgg gcg cgc acc ggt tcc atc gga aca aaa ttg gag 451 Leu Pro Leu Val Trp Ala Arg Thr Gly Ser Ile Gly Thr Lys Leu Glu 105 110 115 ggt gcc agc agg cct ggc cat ttc gat ggt gtg gct acc gtg gtg gcg 499 Gly Ala Ser Arg Pro Gly His Phe Asp Gly Val Ala Thr Val Val Ala 120 125 130 aag ctg ttc aat ttg gtg cgc cct gat cgt gca tat ttt gga caa aaa 547 Lys Leu Phe Asn Leu Val Arg Pro Asp Arg Ala Tyr Phe Gly Gln Lys 135 140 145 gat gct cag cag gtt gcg gtg att cgg cga ttg gtt gcc gat cta gac 595 Asp Ala Gln Gln Val Ala Val Ile Arg Arg Leu Val Ala Asp Leu Asp 150 155 160 165 att ccc gtg gag att cgt ccc gtt ccg att att cgt ggc gcc gat ggc 643 Ile Pro Val Glu Ile Arg Pro Val Pro Ile Ile Arg Gly Ala Asp Gly 170 175 180 tta gcc gaa tcc agc cgc aat caa cgt ctt tct gcg gat cag cga gcg 691 Leu Ala Glu Ser Ser Arg Asn Gln Arg Leu Ser Ala Asp Gln Arg Ala 185 190 195 caa gct ctg gtg ctg ccg cag gtg ttg agt ggg ttg cag cgt cga aaa 739 Gln Ala Leu Val Leu Pro Gln Val Leu Ser Gly Leu Gln Arg Arg Lys 200 205 210 gca gct ggt gaa gcg cta gat atc caa ggt gcg cgc gac acc ttg gcc 787 Ala Ala Gly Glu Ala Leu Asp Ile Gln Gly Ala Arg Asp Thr Leu Ala 215 220 225 agc gcc gac ggc gtg cgc ttg gat cac ctg gaa att gtc gat cca gcc 835 Ser Ala Asp Gly Val Arg Leu Asp His Leu Glu Ile Val Asp Pro Ala 230 235 240 245 acc ctc gaa cca tta gaa atc gac ggc ctg ctc acc caa cca gcg ttg 883 Thr Leu Glu Pro Leu Glu Ile Asp Gly Leu Leu Thr Gln Pro Ala Leu 250 255 260 gtg gtc ggc gcg att ttc gtg ggg ccg gtg cgg ttg atc gac aat atc 931 Val Val Gly Ala Ile Phe Val Gly Pro Val Arg Leu Ile Asp Asn Ile 265 270 275 gag ctc tagtaccaac cctgcgttgc agc 960 Glu Leu <210> 614 <211> 279 <212> PRT <213> Corynebacterium glutamicum <400> 614 Met Gln Val Ala Thr Thr Lys Gln Ala Leu Ile Asp Ala Leu Leu His 1 5 10 15 His Lys Ser Val Gly Leu Val Pro Thr Met Gly Ala Leu His Ser Gly 20 25 30 His Ala Ser Leu Val Lys Ala Ala Arg Ala Glu Asn Asp Thr Val Val 35 40 45 Ala Ser Ile Phe Val Asn Pro Leu Gln Phe Glu Ala Leu Gly Asp Cys 50 55 60 Asp Asp Tyr Arg Asn Tyr Pro Arg Gln Leu Asp Ala Asp Leu Ala Leu 65 70 75 80 Leu Glu Glu Ala Gly Val Asp Ile Val Phe Ala Pro Asp Val Glu Glu 85 90 95 Met Tyr Pro Gly Gly Leu Pro Leu Val Trp Ala Arg Thr Gly Ser Ile 100 105 110 Gly Thr Lys Leu Glu Gly Ala Ser Arg Pro Gly His Phe Asp Gly Val 115 120 125 Ala Thr Val Val Ala Lys Leu Phe Asn Leu Val Arg Pro Asp Arg Ala 130 135 140 Tyr Phe Gly Gln Lys Asp Ala Gln Gln Val Ala Val Ile Arg Arg Leu 145 150 155 160 Val Ala Asp Leu Asp Ile Pro Val Glu Ile Arg Pro Val Pro Ile Ile 165 170 175 Arg Gly Ala Asp Gly Leu Ala Glu Ser Ser Arg Asn Gln Arg Leu Ser 180 185 190 Ala Asp Gln Arg Ala Gln Ala Leu Val Leu Pro Gln Val Leu Ser Gly 195 200 205 Leu Gln Arg Arg Lys Ala Ala Gly Glu Ala Leu Asp Ile Gln Gly Ala 210 215 220 Arg Asp Thr Leu Ala Ser Ala Asp Gly Val Arg Leu Asp His Leu Glu 225 230 235 240 Ile Val Asp Pro Ala Thr Leu Glu Pro Leu Glu Ile Asp Gly Leu Leu 245 250 255 Thr Gln Pro Ala Leu Val Val Gly Ala Ile Phe Val Gly Pro Val Arg 260 265 270 Leu Ile Asp Asn Ile Glu Leu 275 <210> 615 <211> 936 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(913) <223> RXN01929 <400> 615 aaaatttgac tccataacga gaacttaatc gagcaacacc cctgaacagt gaatcaaatc 60 ggaatttatt tattctgagc tggtcatcac atctatactc atg ccc atg tca ggc 115 Met Pro Met Ser Gly 1 5 att gat gca aag aaa atc cgc acc cgt cat ttc cgc gaa gct aaa gta 163 Ile Asp Ala Lys Lys Ile Arg Thr Arg His Phe Arg Glu Ala Lys Val 10 15 20 aac ggc cag aaa gtt tcg gtt ctc acc agc tat gat gcg ctt tcg gcg 211 Asn Gly Gln Lys Val Ser Val Leu Thr Ser Tyr Asp Ala Leu Ser Ala 25 30 35 cgc att ttt gat gag gct ggc gtc gat atg ctc ctt gtt ggt gat tcc 259 Arg Ile Phe Asp Glu Ala Gly Val Asp Met Leu Leu Val Gly Asp Ser 40 45 50 gct gcc aac gtt gtg ctg ggt cgc gat acc acc ttg tcg atc acc ttg 307 Ala Ala Asn Val Val Leu Gly Arg Asp Thr Thr Leu Ser Ile Thr Leu 55 60 65 gat gag atg att gtg ctg gcc aag gcg gtg acg atc gct acg aag cgt 355 Asp Glu Met Ile Val Leu Ala Lys Ala Val Thr Ile Ala Thr Lys Arg 70 75 80 85 gcg ctt gtg gtg gtt gat ctg ccg ttt ggt acc tat gag gtg agc cca 403 Ala Leu Val Val Val Asp Leu Pro Phe Gly Thr Tyr Glu Val Ser Pro 90 95 100 aat cag gcg gtg gag tcc gcg atc cgg gtc atg cgt gaa acg ggt gcg 451 Asn Gln Ala Val Glu Ser Ala Ile Arg Val Met Arg Glu Thr Gly Ala 105 110 115 gct gcg gtg aag atc gag ggt ggc gtg gag atc gcg cag acg att cga 499 Ala Ala Val Lys Ile Glu Gly Gly Val Glu Ile Ala Gln Thr Ile Arg 120 125 130 cgc att gtt gat gct gga att ccg gtt gtc ggc cac atc ggg tac acc 547 Arg Ile Val Asp Ala Gly Ile Pro Val Val Gly His Ile Gly Tyr Thr 135 140 145 ccg cag tcc gag cat tcc ttg ggc ggc cac gtg gtt cag ggt cgt ggc 595 Pro Gln Ser Glu His Ser Leu Gly Gly His Val Val Gln Gly Arg Gly 150 155 160 165 gcg agt tct gga aag ctc atc gcc gat gcc cgc gcg ttg gag cag gcg 643 Ala Ser Ser Gly Lys Leu Ile Ala Asp Ala Arg Ala Leu Glu Gln Ala 170 175 180 ggt gcg ttt gcg gtt gtg ttg gag atg gtt cca gca gag gca gcg cgc 691 Gly Ala Phe Ala Val Val Leu Glu Met Val Pro Ala Glu Ala Ala Arg 185 190 195 gag gtt acc gag gat ctt tcc atc acc act atc gga atc ggt gcc ggc 739 Glu Val Thr Glu Asp Leu Ser Ile Thr Thr Ile Gly Ile Gly Ala Gly 200 205 210 aat ggc aca gat ggg cag gtt ttg gtg tgg cag gat gcc ttc ggc ctc 787 Asn Gly Thr Asp Gly Gln Val Leu Val Trp Gln Asp Ala Phe Gly Leu 215 220 225 aac cgc ggc aag aag cca cgc ttc gtc cgc gag tac gcc acc ttg ggc 835 Asn Arg Gly Lys Lys Pro Arg Phe Val Arg Glu Tyr Ala Thr Leu Gly 230 235 240 245 gat tcc ttg cac gac gcc gcg cag gcc tac atc gcc gat atc cac gcg 883 Asp Ser Leu His Asp Ala Ala Gln Ala Tyr Ile Ala Asp Ile His Ala 250 255 260 ggt acc ttc cca ggc gaa gcg gag tcc ttt taatgcaggt agcaaccaca 933 Gly Thr Phe Pro Gly Glu Ala Glu Ser Phe 265 270 aag 936 <210> 616 <211> 271 <212> PRT <213> Corynebacterium glutamicum <400> 616 Met Pro Met Ser Gly Ile Asp Ala Lys Lys Ile Arg Thr Arg His Phe 1 5 10 15 Arg Glu Ala Lys Val Asn Gly Gln Lys Val Ser Val Leu Thr Ser Tyr 20 25 30 Asp Ala Leu Ser Ala Arg Ile Phe Asp Glu Ala Gly Val Asp Met Leu 35 40 45 Leu Val Gly Asp Ser Ala Ala Asn Val Val Leu Gly Arg Asp Thr Thr 50 55 60 Leu Ser Ile Thr Leu Asp Glu Met Ile Val Leu Ala Lys Ala Val Thr 65 70 75 80 Ile Ala Thr Lys Arg Ala Leu Val Val Val Asp Leu Pro Phe Gly Thr 85 90 95 Tyr Glu Val Ser Pro Asn Gln Ala Val Glu Ser Ala Ile Arg Val Met 100 105 110 Arg Glu Thr Gly Ala Ala Ala Val Lys Ile Glu Gly Gly Val Glu Ile 115 120 125 Ala Gln Thr Ile Arg Arg Ile Val Asp Ala Gly Ile Pro Val Val Gly 130 135 140 His Ile Gly Tyr Thr Pro Gln Ser Glu His Ser Leu Gly Gly His Val 145 150 155 160 Val Gln Gly Arg Gly Ala Ser Ser Gly Lys Leu Ile Ala Asp Ala Arg 165 170 175 Ala Leu Glu Gln Ala Gly Ala Phe Ala Val Val Leu Glu Met Val Pro 180 185 190 Ala Glu Ala Ala Arg Glu Val Thr Glu Asp Leu Ser Ile Thr Thr Ile 195 200 205 Gly Ile Gly Ala Gly Asn Gly Thr Asp Gly Gln Val Leu Val Trp Gln 210 215 220 Asp Ala Phe Gly Leu Asn Arg Gly Lys Lys Pro Arg Phe Val Arg Glu 225 230 235 240 Tyr Ala Thr Leu Gly Asp Ser Leu His Asp Ala Ala Gln Ala Tyr Ile 245 250 255 Ala Asp Ile His Ala Gly Thr Phe Pro Gly Glu Ala Glu Ser Phe 260 265 270 <210> 617 <211> 930 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(907) <223> FRXA01929 <400> 617 tgactccata acgagaactt aatcgagcaa cacccctgaa cagtgaatca aatcggaatt 60 tatttattct gagctggtca tcacatctat actcatgccc atg tca ggc att gat 115 Met Ser Gly Ile Asp 1 5 gca aag aaa atc cgc acc cgt cat ttc cgc gaa gct aaa gta aac ggc 163 Ala Lys Lys Ile Arg Thr Arg His Phe Arg Glu Ala Lys Val Asn Gly 10 15 20 cag aaa gtt tcg gtt ctc acc agc tat gat gcg ctt tcg gcg cgc att 211 Gln Lys Val Ser Val Leu Thr Ser Tyr Asp Ala Leu Ser Ala Arg Ile 25 30 35 ttt gat gag gct ggc gtc gat atg ctc ctt gtt ggt gat tcc gct gcc 259 Phe Asp Glu Ala Gly Val Asp Met Leu Leu Val Gly Asp Ser Ala Ala 40 45 50 aac gtt gtg ctg ggt cgc gat acc acc ttg tcg atc acc ttg gat gag 307 Asn Val Val Leu Gly Arg Asp Thr Thr Leu Ser Ile Thr Leu Asp Glu 55 60 65 atg att gtg ctg gcc aag gcg gtg acg atc gct acg aag cgt gcg ctt 355 Met Ile Val Leu Ala Lys Ala Val Thr Ile Ala Thr Lys Arg Ala Leu 70 75 80 85 gtg gtg gtt gat ctg ccg ttt ggt acc tat gag gtg agc cca aat cag 403 Val Val Val Asp Leu Pro Phe Gly Thr Tyr Glu Val Ser Pro Asn Gln 90 95 100 gcg gtg gag tcc gcg atc cgg gtc atg cgt gaa acg ggt gcg gct gcg 451 Ala Val Glu Ser Ala Ile Arg Val Met Arg Glu Thr Gly Ala Ala Ala 105 110 115 gtg aag atc gag ggt ggc gtg gag atc gcg cag acg att cga cgc att 499 Val Lys Ile Glu Gly Gly Val Glu Ile Ala Gln Thr Ile Arg Arg Ile 120 125 130 gtt gat gct gga att ccg gtt gtc ggc cac atc ggg tac acc ccg cag 547 Val Asp Ala Gly Ile Pro Val Val Gly His Ile Gly Tyr Thr Pro Gln 135 140 145 tcc gag cat tcc ttg ggc ggc cac gtg gtt cag ggt cgt ggc gcg agt 595 Ser Glu His Ser Leu Gly Gly His Val Val Gln Gly Arg Gly Ala Ser 150 155 160 165 tct gga aag ctc atc gcc gat gcc cgc gcg ttg gag cag gcg ggt gcg 643 Ser Gly Lys Leu Ile Ala Asp Ala Arg Ala Leu Glu Gln Ala Gly Ala 170 175 180 ttt gcg gtt gtg ttg gag atg gtt cca gca gag gca gcg cgc gag gtt 691 Phe Ala Val Val Leu Glu Met Val Pro Ala Glu Ala Ala Arg Glu Val 185 190 195 acc gag gat ctt tcc atc acc act atc gga atc ggt gcc ggc aat ggc 739 Thr Glu Asp Leu Ser Ile Thr Thr Ile Gly Ile Gly Ala Gly Asn Gly 200 205 210 aca gat ggg cag gtt ttg gtg tgg cag gat gcc ttc ggc ctc aac cgc 787 Thr Asp Gly Gln Val Leu Val Trp Gln Asp Ala Phe Gly Leu Asn Arg 215 220 225 ggc aag aag cca cgc ttc gtc cgc gag tac gcc acc ttg ggc gat tcc 835 Gly Lys Lys Pro Arg Phe Val Arg Glu Tyr Ala Thr Leu Gly Asp Ser 230 235 240 245 ttg cac gac gcc gcg cag gcc tac atc gcc gat atc cac gcg ggt acc 883 Leu His Asp Ala Ala Gln Ala Tyr Ile Ala Asp Ile His Ala Gly Thr 250 255 260 ttc cca ggc gaa gcg gag tcc ttt taatgcaggt agcaaccaca aag 930 Phe Pro Gly Glu Ala Glu Ser Phe 265 <210> 618 <211> 269 <212> PRT <213> Corynebacterium glutamicum <400> 618 Met Ser Gly Ile Asp Ala Lys Lys Ile Arg Thr Arg His Phe Arg Glu 1 5 10 15 Ala Lys Val Asn Gly Gln Lys Val Ser Val Leu Thr Ser Tyr Asp Ala 20 25 30 Leu Ser Ala Arg Ile Phe Asp Glu Ala Gly Val Asp Met Leu Leu Val 35 40 45 Gly Asp Ser Ala Ala Asn Val Val Leu Gly Arg Asp Thr Thr Leu Ser 50 55 60 Ile Thr Leu Asp Glu Met Ile Val Leu Ala Lys Ala Val Thr Ile Ala 65 70 75 80 Thr Lys Arg Ala Leu Val Val Val Asp Leu Pro Phe Gly Thr Tyr Glu 85 90 95 Val Ser Pro Asn Gln Ala Val Glu Ser Ala Ile Arg Val Met Arg Glu 100 105 110 Thr Gly Ala Ala Ala Val Lys Ile Glu Gly Gly Val Glu Ile Ala Gln 115 120 125 Thr Ile Arg Arg Ile Val Asp Ala Gly Ile Pro Val Val Gly His Ile 130 135 140 Gly Tyr Thr Pro Gln Ser Glu His Ser Leu Gly Gly His Val Val Gln 145 150 155 160 Gly Arg Gly Ala Ser Ser Gly Lys Leu Ile Ala Asp Ala Arg Ala Leu 165 170 175 Glu Gln Ala Gly Ala Phe Ala Val Val Leu Glu Met Val Pro Ala Glu 180 185 190 Ala Ala Arg Glu Val Thr Glu Asp Leu Ser Ile Thr Thr Ile Gly Ile 195 200 205 Gly Ala Gly Asn Gly Thr Asp Gly Gln Val Leu Val Trp Gln Asp Ala 210 215 220 Phe Gly Leu Asn Arg Gly Lys Lys Pro Arg Phe Val Arg Glu Tyr Ala 225 230 235 240 Thr Leu Gly Asp Ser Leu His Asp Ala Ala Gln Ala Tyr Ile Ala Asp 245 250 255 Ile His Ala Gly Thr Phe Pro Gly Glu Ala Glu Ser Phe 260 265 <210> 619 <211> 921 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(898) <223> RXA01521 <400> 619 accccggcag gcaacgcctt ttccgggatt tggcgcgcag gcaggcagag atttcccgcg 60 cgcaagatat tgagctgtgg gcaattcaga aggaggaccg ttg agt ttc acg cat 115 Leu Ser Phe Thr His 1 5 ggt cag ggc aga gtt ttt gat acc gtc gag cag atc cgc atg ttc ggc 163 Gly Gln Gly Arg Val Phe Asp Thr Val Glu Gln Ile Arg Met Phe Gly 10 15 20 agc gcc ctg cgc aaa acc ggc aaa cca gtg gtg ctc gta ccc ttg gga 211 Ser Ala Leu Arg Lys Thr Gly Lys Pro Val Val Leu Val Pro Leu Gly 25 30 35 aat ggc ctc cac gca ggc cat att gcg ctc atc cgc gca gca aaa cgc 259 Asn Gly Leu His Ala Gly His Ile Ala Leu Ile Arg Ala Ala Lys Arg 40 45 50 atc ccc ggt gcg gtg gtc gtc gtc gcc tat gcc ggc ccg gaa tcg gat 307 Ile Pro Gly Ala Val Val Val Val Ala Tyr Ala Gly Pro Glu Ser Asp 55 60 65 cac gca cgt tta agg gaa gag ctt atc gac gcg atc ttc ccg ttc aat 355 His Ala Arg Leu Arg Glu Glu Leu Ile Asp Ala Ile Phe Pro Phe Asn 70 75 80 85 ccc gaa acg cta tgg cct cac ggc atc cgg gtg gaa gtt aca ggt ggc 403 Pro Glu Thr Leu Trp Pro His Gly Ile Arg Val Glu Val Thr Gly Gly 90 95 100 cca aca ctt acc cca caa ggt gcg gaa gta acc aag gtg ctg ggg ctg 451 Pro Thr Leu Thr Pro Gln Gly Ala Glu Val Thr Lys Val Leu Gly Leu 105 110 115 ttg gga atc acc gga gca act gat gtg gtg ctc ggt gaa aag gac tat 499 Leu Gly Ile Thr Gly Ala Thr Asp Val Val Leu Gly Glu Lys Asp Tyr 120 125 130 gag ctg gtg gtt cta gtc cag cgc gcc ctt aat gat ctg cat att cca 547 Glu Leu Val Val Leu Val Gln Arg Ala Leu Asn Asp Leu His Ile Pro 135 140 145 gta aaa ctg cat tct gtt cca acc gtg cgc atg cca gat gga cta gcc 595 Val Lys Leu His Ser Val Pro Thr Val Arg Met Pro Asp Gly Leu Ala 150 155 160 165 att tcc ctg cgt aat att tca gtg ccc gaa gac tcc cgc gaa acg gca 643 Ile Ser Leu Arg Asn Ile Ser Val Pro Glu Asp Ser Arg Glu Thr Ala 170 175 180 ttg agc ctg gca gca gcc ctc acc gcc ggt gcg cat tcg gca gaa cac 691 Leu Ser Leu Ala Ala Ala Leu Thr Ala Gly Ala His Ser Ala Glu His 185 190 195 ggc gag gca gtg gtt aaa gaa aca gtc acg caa gtg ctc aaa gcc gca 739 Gly Glu Ala Val Val Lys Glu Thr Val Thr Gln Val Leu Lys Ala Ala 200 205 210 ggc gtg acc ccc gat tat gta gaa atc cgt ggc ctg gat ctt gga cca 787 Gly Val Thr Pro Asp Tyr Val Glu Ile Arg Gly Leu Asp Leu Gly Pro 215 220 225 gcc ccc gaa atc gga gac gcc cga ctc ttc gca gcc atc acg ctt ggc 835 Ala Pro Glu Ile Gly Asp Ala Arg Leu Phe Ala Ala Ile Thr Leu Gly 230 235 240 245 gat gtc caa ctc cac gac aac gtc ggc cta ccc ctt gga atc ggc ttc 883 Asp Val Gln Leu His Asp Asn Val Gly Leu Pro Leu Gly Ile Gly Phe 250 255 260 aaa aac atc gaa ggc tgatcccggt ttacccagtt cgc 921 Lys Asn Ile Glu Gly 265 <210> 620 <211> 266 <212> PRT <213> Corynebacterium glutamicum <400> 620 Leu Ser Phe Thr His Gly Gln Gly Arg Val Phe Asp Thr Val Glu Gln 1 5 10 15 Ile Arg Met Phe Gly Ser Ala Leu Arg Lys Thr Gly Lys Pro Val Val 20 25 30 Leu Val Pro Leu Gly Asn Gly Leu His Ala Gly His Ile Ala Leu Ile 35 40 45 Arg Ala Ala Lys Arg Ile Pro Gly Ala Val Val Val Val Ala Tyr Ala 50 55 60 Gly Pro Glu Ser Asp His Ala Arg Leu Arg Glu Glu Leu Ile Asp Ala 65 70 75 80 Ile Phe Pro Phe Asn Pro Glu Thr Leu Trp Pro His Gly Ile Arg Val 85 90 95 Glu Val Thr Gly Gly Pro Thr Leu Thr Pro Gln Gly Ala Glu Val Thr 100 105 110 Lys Val Leu Gly Leu Leu Gly Ile Thr Gly Ala Thr Asp Val Val Leu 115 120 125 Gly Glu Lys Asp Tyr Glu Leu Val Val Leu Val Gln Arg Ala Leu Asn 130 135 140 Asp Leu His Ile Pro Val Lys Leu His Ser Val Pro Thr Val Arg Met 145 150 155 160 Pro Asp Gly Leu Ala Ile Ser Leu Arg Asn Ile Ser Val Pro Glu Asp 165 170 175 Ser Arg Glu Thr Ala Leu Ser Leu Ala Ala Ala Leu Thr Ala Gly Ala 180 185 190 His Ser Ala Glu His Gly Glu Ala Val Val Lys Glu Thr Val Thr Gln 195 200 205 Val Leu Lys Ala Ala Gly Val Thr Pro Asp Tyr Val Glu Ile Arg Gly 210 215 220 Leu Asp Leu Gly Pro Ala Pro Glu Ile Gly Asp Ala Arg Leu Phe Ala 225 230 235 240 Ala Ile Thr Leu Gly Asp Val Gln Leu His Asp Asn Val Gly Leu Pro 245 250 255 Leu Gly Ile Gly Phe Lys Asn Ile Glu Gly 260 265 <210> 621 <211> 1137 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1114) <223> RXS01145 <400> 621 taatgtagtt gtctgcccaa gcgagttaaa ctcccacgat ttacagtggg gggcagacat 60 cttttcacca aaatttttac gaaaggcgag attttctccc atg gct att gaa ctg 115 Met Ala Ile Glu Leu 1 5 ctt tat gat gct gac gct gac ctc tcc ttg atc cag ggc cgt aag gtt 163 Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile Gln Gly Arg Lys Val 10 15 20 gcc atc gtt ggc tac ggc tcc cag ggc cac gca cac tcc cag aac ctc 211 Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala His Ser Gln Asn Leu 25 30 35 cgc gat tct ggc gtt gag gtt gtc att ggt ctg cgc gag ggc tcc aag 259 Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu Arg Glu Gly Ser Lys 40 45 50 tcc gca gag aag gca aag gaa gca ggc ttc gag gtc aag acc acc gct 307 Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu Val Lys Thr Thr Ala 55 60 65 gag gct gca gct tgg gct gac gtc atc atg ctc ctg gct cca gac acc 355 Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu Leu Ala Pro Asp Thr 70 75 80 85 tcc cag gca gaa atc ttc acc aac gac atc gag cca aac ctg aac gca 403 Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu Pro Asn Leu Asn Ala 90 95 100 ggc gac gca ctg ctg ttc ggc cac ggc ctg aac att cac ttc gac ctg 451 Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn Ile His Phe Asp Leu 105 110 115 atc aag cca gct gac gac atc atc gtt ggc atg gtt gcg cca aag ggc 499 Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met Val Ala Pro Lys Gly 120 125 130 cca ggc cac ttg gtt cgc cgt cag ttc gtt gat ggc aag ggt gtt cct 547 Pro Gly His Leu Val Arg Arg Gln Phe Val Asp Gly Lys Gly Val Pro 135 140 145 tgc ctc atc gca gtc gac cag gac cca acc gga acc gca cag gct ctg 595 Cys Leu Ile Ala Val Asp Gln Asp Pro Thr Gly Thr Ala Gln Ala Leu 150 155 160 165 acc ctg tcc tac gca gca gca atc ggt ggc gca cgc gca ggc gtt atc 643 Thr Leu Ser Tyr Ala Ala Ala Ile Gly Gly Ala Arg Ala Gly Val Ile 170 175 180 cca acc acc ttc gaa gct gag acc gtc acc gac ctc ttc ggc gag cag 691 Pro Thr Thr Phe Glu Ala Glu Thr Val Thr Asp Leu Phe Gly Glu Gln 185 190 195 gct gtt ctc tgc ggt ggc acc gag gaa ctg gtc aag gtt ggc ttc gag 739 Ala Val Leu Cys Gly Gly Thr Glu Glu Leu Val Lys Val Gly Phe Glu 200 205 210 gtt ctc acc gaa gct ggc tac gag cca gag atg gca tac ttc gag gtt 787 Val Leu Thr Glu Ala Gly Tyr Glu Pro Glu Met Ala Tyr Phe Glu Val 215 220 225 ctt cac gag ctc aag ctc atc gtt gac ctc atg ttc gaa ggt ggc atc 835 Leu His Glu Leu Lys Leu Ile Val Asp Leu Met Phe Glu Gly Gly Ile 230 235 240 245 agc aac atg aac tac tct gtt tct gac acc gct gag ttc ggt ggc tac 883 Ser Asn Met Asn Tyr Ser Val Ser Asp Thr Ala Glu Phe Gly Gly Tyr 250 255 260 ctc tcc ggc cca cgc gtc atc gat gca gac acc aag tcc cgc atg aag 931 Leu Ser Gly Pro Arg Val Ile Asp Ala Asp Thr Lys Ser Arg Met Lys 265 270 275 gac atc ctg acc gat atc cag gac ggc acc ttc acc aag cgc ctc atc 979 Asp Ile Leu Thr Asp Ile Gln Asp Gly Thr Phe Thr Lys Arg Leu Ile 280 285 290 gca aac gtt gag aac ggc aac acc gag ctt gag ggc ctt cgt gct tcc 1027 Ala Asn Val Glu Asn Gly Asn Thr Glu Leu Glu Gly Leu Arg Ala Ser 295 300 305 tac aac aac cac cca atc gag gag acc ggc gct aag ctc cgc gac ctc 1075 Tyr Asn Asn His Pro Ile Glu Glu Thr Gly Ala Lys Leu Arg Asp Leu 310 315 320 325 atg agc tgg gtc aag gtt gac gct cgc gca gaa acc gct taagtttcac 1124 Met Ser Trp Val Lys Val Asp Ala Arg Ala Glu Thr Ala 330 335 ccctttgacg gct 1137 <210> 622 <211> 338 <212> PRT <213> Corynebacterium glutamicum <400> 622 Met Ala Ile Glu Leu Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile 1 5 10 15 Gln Gly Arg Lys Val Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala 20 25 30 His Ser Gln Asn Leu Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu 35 40 45 Arg Glu Gly Ser Lys Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu 50 55 60 Val Lys Thr Thr Ala Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu 65 70 75 80 Leu Ala Pro Asp Thr Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu 85 90 95 Pro Asn Leu Asn Ala Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn 100 105 110 Ile His Phe Asp Leu Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met 115 120 125 Val Ala Pro Lys Gly Pro Gly His Leu Val Arg Arg Gln Phe Val Asp 130 135 140 Gly Lys Gly Val Pro Cys Leu Ile Ala Val Asp Gln Asp Pro Thr Gly 145 150 155 160 Thr Ala Gln Ala Leu Thr Leu Ser Tyr Ala Ala Ala Ile Gly Gly Ala 165 170 175 Arg Ala Gly Val Ile Pro Thr Thr Phe Glu Ala Glu Thr Val Thr Asp 180 185 190 Leu Phe Gly Glu Gln Ala Val Leu Cys Gly Gly Thr Glu Glu Leu Val 195 200 205 Lys Val Gly Phe Glu Val Leu Thr Glu Ala Gly Tyr Glu Pro Glu Met 210 215 220 Ala Tyr Phe Glu Val Leu His Glu Leu Lys Leu Ile Val Asp Leu Met 225 230 235 240 Phe Glu Gly Gly Ile Ser Asn Met Asn Tyr Ser Val Ser Asp Thr Ala 245 250 255 Glu Phe Gly Gly Tyr Leu Ser Gly Pro Arg Val Ile Asp Ala Asp Thr 260 265 270 Lys Ser Arg Met Lys Asp Ile Leu Thr Asp Ile Gln Asp Gly Thr Phe 275 280 285 Thr Lys Arg Leu Ile Ala Asn Val Glu Asn Gly Asn Thr Glu Leu Glu 290 295 300 Gly Leu Arg Ala Ser Tyr Asn Asn His Pro Ile Glu Glu Thr Gly Ala 305 310 315 320 Lys Leu Arg Asp Leu Met Ser Trp Val Lys Val Asp Ala Arg Ala Glu 325 330 335 Thr Ala <210> 623 <211> 556 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(556) <223> FRXA01145 <400> 623 taatgtagtt gtctgcccaa gcgagttaaa ctcccacgat ttacagtggg gggcagacat 60 cttttcacca aaatttttac gaaaggcgag attttctccc atg gct att gaa ctg 115 Met Ala Ile Glu Leu 1 5 ctt tat gat gct gac gct gac ctc tcc ttg atc cag ggc cgt aag gtt 163 Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile Gln Gly Arg Lys Val 10 15 20 gcc atc gtt ggc tac ggc tcc cag ggc cac gca cac tcc cag aac ctc 211 Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala His Ser Gln Asn Leu 25 30 35 cgc gat tct ggc gtt gag gtt gtc att ggt ctg cgc gag ggc tcc aag 259 Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu Arg Glu Gly Ser Lys 40 45 50 tcc gca gag aag gca aag gaa gca ggc ttc gag gtc aag acc acc gct 307 Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu Val Lys Thr Thr Ala 55 60 65 gag gct gca gct tgg gct gac gtc atc atg ctc ctg gct cca gac acc 355 Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu Leu Ala Pro Asp Thr 70 75 80 85 tcc cag gca gaa atc ttc acc aac gac atc gag cca aac ctg aac gca 403 Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu Pro Asn Leu Asn Ala 90 95 100 ggc gac gca ctg ctg ttc ggc cac ggc ctg aac att cac ttc gac ctg 451 Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn Ile His Phe Asp Leu 105 110 115 atc aag cca gct gac gac atc atc gtt ggc atg gtt gcg cca aag ggc 499 Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met Val Ala Pro Lys Gly 120 125 130 cca ggc cac ttg gtt cgc cgt cag ttc gtt gat ggc aag ggt gtt cct 547 Pro Gly His Leu Val Arg Arg Gln Phe Val Asp Gly Lys Gly Val Pro 135 140 145 tgc ctc atc 556 Cys Leu Ile 150 <210> 624 <211> 152 <212> PRT <213> Corynebacterium glutamicum <400> 624 Met Ala Ile Glu Leu Leu Tyr Asp Ala Asp Ala Asp Leu Ser Leu Ile 1 5 10 15 Gln Gly Arg Lys Val Ala Ile Val Gly Tyr Gly Ser Gln Gly His Ala 20 25 30 His Ser Gln Asn Leu Arg Asp Ser Gly Val Glu Val Val Ile Gly Leu 35 40 45 Arg Glu Gly Ser Lys Ser Ala Glu Lys Ala Lys Glu Ala Gly Phe Glu 50 55 60 Val Lys Thr Thr Ala Glu Ala Ala Ala Trp Ala Asp Val Ile Met Leu 65 70 75 80 Leu Ala Pro Asp Thr Ser Gln Ala Glu Ile Phe Thr Asn Asp Ile Glu 85 90 95 Pro Asn Leu Asn Ala Gly Asp Ala Leu Leu Phe Gly His Gly Leu Asn 100 105 110 Ile His Phe Asp Leu Ile Lys Pro Ala Asp Asp Ile Ile Val Gly Met 115 120 125 Val Ala Pro Lys Gly Pro Gly His Leu Val Arg Arg Gln Phe Val Asp 130 135 140 Gly Lys Gly Val Pro Cys Leu Ile 145 150 <210> 625 <211> 1389 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1366) <223> RXA02239 <400> 625 ctatgcacag cggaggtcga gggagagcgt ggggtggcgt cgaaaagcat cttgtagagt 60 gtgtgggaac ccagccagcc tcttactttg aaggattgtt gtg ccc atg act cat 115 Val Pro Met Thr His 1 5 gtt tca agc ccc tcc gca ccc cgc aac gtg gtt gtt ggt gtt gcc ggc 163 Val Ser Ser Pro Ser Ala Pro Arg Asn Val Val Val Gly Val Ala Gly 10 15 20 gga atc gca gcg tac aag gcg tgt cac atc gtg cgc gcg ttt aaa gaa 211 Gly Ile Ala Ala Tyr Lys Ala Cys His Ile Val Arg Ala Phe Lys Glu 25 30 35 gcg ggc gat aat gtg cgg gtg gtt cct acg gaa tcc gcg ttg aag ttt 259 Ala Gly Asp Asn Val Arg Val Val Pro Thr Glu Ser Ala Leu Lys Phe 40 45 50 gtg ggg aag gcg acg ttt gaa gcg ttg tct ggc aat ccg gtg tct aca 307 Val Gly Lys Ala Thr Phe Glu Ala Leu Ser Gly Asn Pro Val Ser Thr 55 60 65 acg gtg ttt gat gcg gtg gat tcg gtg cag cat gtg aaa gtt ggc cag 355 Thr Val Phe Asp Ala Val Asp Ser Val Gln His Val Lys Val Gly Gln 70 75 80 85 gaa gct gat ttg atc gtg att gcg ccg gcg aca gcc gat ttg atg gcg 403 Glu Ala Asp Leu Ile Val Ile Ala Pro Ala Thr Ala Asp Leu Met Ala 90 95 100 cgt gtg gtg gca ggt ctc ggt gac gat ctg ttg gcg gcg acg ctg ctg 451 Arg Val Val Ala Gly Leu Gly Asp Asp Leu Leu Ala Ala Thr Leu Leu 105 110 115 gtg gca acg tgc ccc gtg gtt att gcg ccg gcc atg cat acg gag atg 499 Val Ala Thr Cys Pro Val Val Ile Ala Pro Ala Met His Thr Glu Met 120 125 130 tgg ttt aat ccg gct acc gta gcc aat gtg gca acg ctg agg cag cgg 547 Trp Phe Asn Pro Ala Thr Val Ala Asn Val Ala Thr Leu Arg Gln Arg 135 140 145 ggg att acc gtg att gag cct gcg cat ggt cga ctc acc ggt aaa gat 595 Gly Ile Thr Val Ile Glu Pro Ala His Gly Arg Leu Thr Gly Lys Asp 150 155 160 165 aca ggc cct ggc cgg ctg ccg gat cca gag cag att gtt gat tta gcc 643 Thr Gly Pro Gly Arg Leu Pro Asp Pro Glu Gln Ile Val Asp Leu Ala 170 175 180 aat gcg gtg cac gcc ggg gcg agg ttg cct cag gat ttg gcg ggc aag 691 Asn Ala Val His Ala Gly Ala Arg Leu Pro Gln Asp Leu Ala Gly Lys 185 190 195 aaa gtg ctg atc act gct ggt ggc acg cat gag cat att gat cct gtg 739 Lys Val Leu Ile Thr Ala Gly Gly Thr His Glu His Ile Asp Pro Val 200 205 210 cgc ttt att ggc aat agt tcc tcg ggc cgt caa ggt ttt gcg ttg ggt 787 Arg Phe Ile Gly Asn Ser Ser Ser Gly Arg Gln Gly Phe Ala Leu Gly 215 220 225 gaa atc gca gca cag cga ggt gct cat gtc agc atc gtg gcg gga aat 835 Glu Ile Ala Ala Gln Arg Gly Ala His Val Ser Ile Val Ala Gly Asn 230 235 240 245 gct gcg gag ctg ccc act ccg gca ggc gca gag atc gtg ccg gtg gtg 883 Ala Ala Glu Leu Pro Thr Pro Ala Gly Ala Glu Ile Val Pro Val Val 250 255 260 tcc aca caa gac atg ttt gat gca gtc cag gaa cga gct ggc caa tct 931 Ser Thr Gln Asp Met Phe Asp Ala Val Gln Glu Arg Ala Gly Gln Ser 265 270 275 gat ttc atc gtc atg gcg gca gcg gta gct gat ttc acg ccc gca tcg 979 Asp Phe Ile Val Met Ala Ala Ala Val Ala Asp Phe Thr Pro Ala Ser 280 285 290 cag gcg aca tcg aag ttg aag aag ggc tca gat tct gat gaa gac gca 1027 Gln Ala Thr Ser Lys Leu Lys Lys Gly Ser Asp Ser Asp Glu Asp Ala 295 300 305 ttg agc acc atc tcg ttg gtg gaa aac ccg gat att ttg gct acc acg 1075 Leu Ser Thr Ile Ser Leu Val Glu Asn Pro Asp Ile Leu Ala Thr Thr 310 315 320 325 gtg aag cgt cgt gaa gca gga gag ctg gac agt aat cct gtc atc gtg 1123 Val Lys Arg Arg Glu Ala Gly Glu Leu Asp Ser Asn Pro Val Ile Val 330 335 340 ggt ttt gct gcg gaa act gga gac gag cac acc acc gcc ttg gag tat 1171 Gly Phe Ala Ala Glu Thr Gly Asp Glu His Thr Thr Ala Leu Glu Tyr 345 350 355 gcg cgc aag aaa ctg cag aag aag ggc tgc gac ctc ctc atg tgt aat 1219 Ala Arg Lys Lys Leu Gln Lys Lys Gly Cys Asp Leu Leu Met Cys Asn 360 365 370 gag gtg ggc atg ggc aaa gtg ttt ggg caa aag cac aat gag ggc tgg 1267 Glu Val Gly Met Gly Lys Val Phe Gly Gln Lys His Asn Glu Gly Trp 375 380 385 att ttg gat gct cac ggt ggg gta gtc gat gtg gag cac ggc agc aaa 1315 Ile Leu Asp Ala His Gly Gly Val Val Asp Val Glu His Gly Ser Lys 390 395 400 405 atc gag gtt gct gcg caa att tgg gac gcg gca ctg gcg tat cgc gaa 1363 Ile Glu Val Ala Ala Gln Ile Trp Asp Ala Ala Leu Ala Tyr Arg Glu 410 415 420 gtc tagaaaaatc cagctagacc act 1389 Val <210> 626 <211> 422 <212> PRT <213> Corynebacterium glutamicum <400> 626 Val Pro Met Thr His Val Ser Ser Pro Ser Ala Pro Arg Asn Val Val 1 5 10 15 Val Gly Val Ala Gly Gly Ile Ala Ala Tyr Lys Ala Cys His Ile Val 20 25 30 Arg Ala Phe Lys Glu Ala Gly Asp Asn Val Arg Val Val Pro Thr Glu 35 40 45 Ser Ala Leu Lys Phe Val Gly Lys Ala Thr Phe Glu Ala Leu Ser Gly 50 55 60 Asn Pro Val Ser Thr Thr Val Phe Asp Ala Val Asp Ser Val Gln His 65 70 75 80 Val Lys Val Gly Gln Glu Ala Asp Leu Ile Val Ile Ala Pro Ala Thr 85 90 95 Ala Asp Leu Met Ala Arg Val Val Ala Gly Leu Gly Asp Asp Leu Leu 100 105 110 Ala Ala Thr Leu Leu Val Ala Thr Cys Pro Val Val Ile Ala Pro Ala 115 120 125 Met His Thr Glu Met Trp Phe Asn Pro Ala Thr Val Ala Asn Val Ala 130 135 140 Thr Leu Arg Gln Arg Gly Ile Thr Val Ile Glu Pro Ala His Gly Arg 145 150 155 160 Leu Thr Gly Lys Asp Thr Gly Pro Gly Arg Leu Pro Asp Pro Glu Gln 165 170 175 Ile Val Asp Leu Ala Asn Ala Val His Ala Gly Ala Arg Leu Pro Gln 180 185 190 Asp Leu Ala Gly Lys Lys Val Leu Ile Thr Ala Gly Gly Thr His Glu 195 200 205 His Ile Asp Pro Val Arg Phe Ile Gly Asn Ser Ser Ser Gly Arg Gln 210 215 220 Gly Phe Ala Leu Gly Glu Ile Ala Ala Gln Arg Gly Ala His Val Ser 225 230 235 240 Ile Val Ala Gly Asn Ala Ala Glu Leu Pro Thr Pro Ala Gly Ala Glu 245 250 255 Ile Val Pro Val Val Ser Thr Gln Asp Met Phe Asp Ala Val Gln Glu 260 265 270 Arg Ala Gly Gln Ser Asp Phe Ile Val Met Ala Ala Ala Val Ala Asp 275 280 285 Phe Thr Pro Ala Ser Gln Ala Thr Ser Lys Leu Lys Lys Gly Ser Asp 290 295 300 Ser Asp Glu Asp Ala Leu Ser Thr Ile Ser Leu Val Glu Asn Pro Asp 305 310 315 320 Ile Leu Ala Thr Thr Val Lys Arg Arg Glu Ala Gly Glu Leu Asp Ser 325 330 335 Asn Pro Val Ile Val Gly Phe Ala Ala Glu Thr Gly Asp Glu His Thr 340 345 350 Thr Ala Leu Glu Tyr Ala Arg Lys Lys Leu Gln Lys Lys Gly Cys Asp 355 360 365 Leu Leu Met Cys Asn Glu Val Gly Met Gly Lys Val Phe Gly Gln Lys 370 375 380 His Asn Glu Gly Trp Ile Leu Asp Ala His Gly Gly Val Val Asp Val 385 390 395 400 Glu His Gly Ser Lys Ile Glu Val Ala Ala Gln Ile Trp Asp Ala Ala 405 410 415 Leu Ala Tyr Arg Glu Val 420 <210> 627 <211> 1092 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1069) <223> RXA00581 <400> 627 gcatgagttt actcacgtgc ccacgtcttt tagccaccca ttgaagtgaa aaaataaccc 60 cgatcacact agtggagtag ctaaggtgca caatggattc atg gca gag caa aac 115 Met Ala Glu Gln Asn 1 5 gct gca agc aca act ggt gtg aaa cct tcc cca cgc aca cca gat ttc 163 Ala Ala Ser Thr Thr Gly Val Lys Pro Ser Pro Arg Thr Pro Asp Phe 10 15 20 agc ccc tac ctt gat ttc gac cgc gca caa tgg cgc gag ctg aga aac 211 Ser Pro Tyr Leu Asp Phe Asp Arg Ala Gln Trp Arg Glu Leu Arg Asn 25 30 35 tca atg cct cag gtg ctg acc caa aaa gaa gtc att gaa ctt cga ggc 259 Ser Met Pro Gln Val Leu Thr Gln Lys Glu Val Ile Glu Leu Arg Gly 40 45 50 atc gga gaa aac att gac ctc gct gaa gtg gca gaa gtc tac ctt ccg 307 Ile Gly Glu Asn Ile Asp Leu Ala Glu Val Ala Glu Val Tyr Leu Pro 55 60 65 ctg tcc cgt ctg att cac ctc cag gta gcg gcc cga cag caa ctt act 355 Leu Ser Arg Leu Ile His Leu Gln Val Ala Ala Arg Gln Gln Leu Thr 70 75 80 85 gca gcc acc gaa acc ttc ctc gga act tcc ccc tct atc tct gtg ccg 403 Ala Ala Thr Glu Thr Phe Leu Gly Thr Ser Pro Ser Ile Ser Val Pro 90 95 100 ttt gtc att ggt gtc gcg gga tcc gtc gcc gtc ggt aaa tca acc acc 451 Phe Val Ile Gly Val Ala Gly Ser Val Ala Val Gly Lys Ser Thr Thr 105 110 115 gcc cga ctc ctc caa gtt ctg ctt cag cgc tgg aat tcc cac ccc cgc 499 Ala Arg Leu Leu Gln Val Leu Leu Gln Arg Trp Asn Ser His Pro Arg 120 125 130 gtg gac ctc gtc acc acc gac gga ttc ctc tat ccc ggc gcg gaa cta 547 Val Asp Leu Val Thr Thr Asp Gly Phe Leu Tyr Pro Gly Ala Glu Leu 135 140 145 atc cgc cgc gga tta atg tcc cga aaa gga ttc ccc gaa agc tac gac 595 Ile Arg Arg Gly Leu Met Ser Arg Lys Gly Phe Pro Glu Ser Tyr Asp 150 155 160 165 caa cgt gca ctc ctc cgc ttt gtc acc gac gta aaa tcc gga aaa ctc 643 Gln Arg Ala Leu Leu Arg Phe Val Thr Asp Val Lys Ser Gly Lys Leu 170 175 180 gaa gtc aac gca cct gtc tac tcc cac acc gcg tac gac cga gtt cca 691 Glu Val Asn Ala Pro Val Tyr Ser His Thr Ala Tyr Asp Arg Val Pro 185 190 195 ggc gaa ttc acc aca gtc cgc caa ccc gac att ttg atc gtc gaa ggc 739 Gly Glu Phe Thr Thr Val Arg Gln Pro Asp Ile Leu Ile Val Glu Gly 200 205 210 tta aac gtc ctc caa act ggc cca aca ttg atg gtc agt gac ctt ttc 787 Leu Asn Val Leu Gln Thr Gly Pro Thr Leu Met Val Ser Asp Leu Phe 215 220 225 gac ttc agc gtc tac gta gat gcc cgc acc gaa gat atc gaa aaa tgg 835 Asp Phe Ser Val Tyr Val Asp Ala Arg Thr Glu Asp Ile Glu Lys Trp 230 235 240 245 tac atc gac cgc ttc ctc aaa ctc cgc gac act gca ttc cgt cgc ccc 883 Tyr Ile Asp Arg Phe Leu Lys Leu Arg Asp Thr Ala Phe Arg Arg Pro 250 255 260 ggt gcc cac ttc tcc cat tac gcc gac atg gct gat cca gag tcc atc 931 Gly Ala His Phe Ser His Tyr Ala Asp Met Ala Asp Pro Glu Ser Ile 265 270 275 gcc gtc gct cga gaa ctg tgg caa tcg atc aac ctg ccc aac ttg gtg 979 Ala Val Ala Arg Glu Leu Trp Gln Ser Ile Asn Leu Pro Asn Leu Val 280 285 290 gag aat att ctt ccc acc cga gtt cgc gcg tcg ttg gta ctg aaa aaa 1027 Glu Asn Ile Leu Pro Thr Arg Val Arg Ala Ser Leu Val Leu Lys Lys 295 300 305 ggt agc gat cac ttg gtg gaa cgg gtg agg atg cgc aag atc 1069 Gly Ser Asp His Leu Val Glu Arg Val Arg Met Arg Lys Ile 310 315 320 taggggttct tgctggtttt gag 1092 <210> 628 <211> 323 <212> PRT <213> Corynebacterium glutamicum <400> 628 Met Ala Glu Gln Asn Ala Ala Ser Thr Thr Gly Val Lys Pro Ser Pro 1 5 10 15 Arg Thr Pro Asp Phe Ser Pro Tyr Leu Asp Phe Asp Arg Ala Gln Trp 20 25 30 Arg Glu Leu Arg Asn Ser Met Pro Gln Val Leu Thr Gln Lys Glu Val 35 40 45 Ile Glu Leu Arg Gly Ile Gly Glu Asn Ile Asp Leu Ala Glu Val Ala 50 55 60 Glu Val Tyr Leu Pro Leu Ser Arg Leu Ile His Leu Gln Val Ala Ala 65 70 75 80 Arg Gln Gln Leu Thr Ala Ala Thr Glu Thr Phe Leu Gly Thr Ser Pro 85 90 95 Ser Ile Ser Val Pro Phe Val Ile Gly Val Ala Gly Ser Val Ala Val 100 105 110 Gly Lys Ser Thr Thr Ala Arg Leu Leu Gln Val Leu Leu Gln Arg Trp 115 120 125 Asn Ser His Pro Arg Val Asp Leu Val Thr Thr Asp Gly Phe Leu Tyr 130 135 140 Pro Gly Ala Glu Leu Ile Arg Arg Gly Leu Met Ser Arg Lys Gly Phe 145 150 155 160 Pro Glu Ser Tyr Asp Gln Arg Ala Leu Leu Arg Phe Val Thr Asp Val 165 170 175 Lys Ser Gly Lys Leu Glu Val Asn Ala Pro Val Tyr Ser His Thr Ala 180 185 190 Tyr Asp Arg Val Pro Gly Glu Phe Thr Thr Val Arg Gln Pro Asp Ile 195 200 205 Leu Ile Val Glu Gly Leu Asn Val Leu Gln Thr Gly Pro Thr Leu Met 210 215 220 Val Ser Asp Leu Phe Asp Phe Ser Val Tyr Val Asp Ala Arg Thr Glu 225 230 235 240 Asp Ile Glu Lys Trp Tyr Ile Asp Arg Phe Leu Lys Leu Arg Asp Thr 245 250 255 Ala Phe Arg Arg Pro Gly Ala His Phe Ser His Tyr Ala Asp Met Ala 260 265 270 Asp Pro Glu Ser Ile Ala Val Ala Arg Glu Leu Trp Gln Ser Ile Asn 275 280 285 Leu Pro Asn Leu Val Glu Asn Ile Leu Pro Thr Arg Val Arg Ala Ser 290 295 300 Leu Val Leu Lys Lys Gly Ser Asp His Leu Val Glu Arg Val Arg Met 305 310 315 320 Arg Lys Ile <210> 629 <211> 1023 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1000) <223> RXS00838 <400> 629 tcgtctaata gtgctgccaa tccaccggcc attgatgact cctttgtaga gaaggggtag 60 tgcttacaaa tcttatctgt gctcaggcaa gatagcaggt atg aaa att gcg atc 115 Met Lys Ile Ala Ile 1 5 gtt ggc gct ggt gca gtt ggt gga tat ttc gga gcg ttg tta caa gaa 163 Val Gly Ala Gly Ala Val Gly Gly Tyr Phe Gly Ala Leu Leu Gln Glu 10 15 20 tct ggt gca gat atc acg atg gtt gca cgt gga cga aca tta gaa gcc 211 Ser Gly Ala Asp Ile Thr Met Val Ala Arg Gly Arg Thr Leu Glu Ala 25 30 35 ttg aag tct aaa gga ctc cac atc aac gat gca aga ggc gaa cgc tac 259 Leu Lys Ser Lys Gly Leu His Ile Asn Asp Ala Arg Gly Glu Arg Tyr 40 45 50 gta cca att cct gca gtt gcg agc gtg caa gaa cta aaa gat gca gat 307 Val Pro Ile Pro Ala Val Ala Ser Val Gln Glu Leu Lys Asp Ala Asp 55 60 65 gta gtg atg att gct act aaa gca tta tcg cgg tct tta gat ctc gct 355 Val Val Met Ile Ala Thr Lys Ala Leu Ser Arg Ser Leu Asp Leu Ala 70 75 80 85 gaa ctt ttg ggt ggg ata cct gcg aat tcg gtg gtc gcg att act cag 403 Glu Leu Leu Gly Gly Ile Pro Ala Asn Ser Val Val Ala Ile Thr Gln 90 95 100 aat tcg att gaa tct gct gat cta gca gcg aag agt atc ggt gct gat 451 Asn Ser Ile Glu Ser Ala Asp Leu Ala Ala Lys Ser Ile Gly Ala Asp 105 110 115 cgt gtg tgg cct ggt gtg gtt cgt ggg ttc ttt gtt cat gag ggg cca 499 Arg Val Trp Pro Gly Val Val Arg Gly Phe Phe Val His Glu Gly Pro 120 125 130 gcc tca gtg tca tac aag gga ggc cca ctg tcc tac acg ttt ggt gat 547 Ala Ser Val Ser Tyr Lys Gly Gly Pro Leu Ser Tyr Thr Phe Gly Asp 135 140 145 tct ggt gaa ctt tct agg caa ttc gca agc act ctt gaa cag gcc ggt 595 Ser Gly Glu Leu Ser Arg Gln Phe Ala Ser Thr Leu Glu Gln Ala Gly 150 155 160 165 att gac gga gtt ctg cat ccc gat att ttg gtg gat gtg tgg gag aaa 643 Ile Asp Gly Val Leu His Pro Asp Ile Leu Val Asp Val Trp Glu Lys 170 175 180 gcc atg ttc gta gag gtt ttc ggc ggg ttg ggg gct ttc gtc gaa aag 691 Ala Met Phe Val Glu Val Phe Gly Gly Leu Gly Ala Phe Val Glu Lys 185 190 195 caa tta ggt acc ttg cgt acg cat ttt agg gct tcc ctg gaa gcc ttg 739 Gln Leu Gly Thr Leu Arg Thr His Phe Arg Ala Ser Leu Glu Ala Leu 200 205 210 atg gaa gag gtg gct gag gtg gct cgc gcg gca ggt gtt gcg ttg ccg 787 Met Glu Glu Val Ala Glu Val Ala Arg Ala Ala Gly Val Ala Leu Pro 215 220 225 agc gat gcg gtg gag cgc acc atg aat ttt gcg gat cgg atg cct gag 835 Ser Asp Ala Val Glu Arg Thr Met Asn Phe Ala Asp Arg Met Pro Glu 230 235 240 245 aat tcg acg agt tcg atg cag cgt gat ttg gcc gcg gga gtg gct agt 883 Asn Ser Thr Ser Ser Met Gln Arg Asp Leu Ala Ala Gly Val Ala Ser 250 255 260 gag ctt gag gct cag aca ggt gca att gtg cgg gca gcg cac aaa gtg 931 Glu Leu Glu Ala Gln Thr Gly Ala Ile Val Arg Ala Ala His Lys Val 265 270 275 ggt gtg aaa act ccg ctt cat gac ctt att tat gct ggt ctt aag ctg 979 Gly Val Lys Thr Pro Leu His Asp Leu Ile Tyr Ala Gly Leu Lys Leu 280 285 290 aaa gaa gag gaa aat tca ctt tagggataga atcaagatcc atg 1023 Lys Glu Glu Glu Asn Ser Leu 295 300 <210> 630 <211> 300 <212> PRT <213> Corynebacterium glutamicum <400> 630 Met Lys Ile Ala Ile Val Gly Ala Gly Ala Val Gly Gly Tyr Phe Gly 1 5 10 15 Ala Leu Leu Gln Glu Ser Gly Ala Asp Ile Thr Met Val Ala Arg Gly 20 25 30 Arg Thr Leu Glu Ala Leu Lys Ser Lys Gly Leu His Ile Asn Asp Ala 35 40 45 Arg Gly Glu Arg Tyr Val Pro Ile Pro Ala Val Ala Ser Val Gln Glu 50 55 60 Leu Lys Asp Ala Asp Val Val Met Ile Ala Thr Lys Ala Leu Ser Arg 65 70 75 80 Ser Leu Asp Leu Ala Glu Leu Leu Gly Gly Ile Pro Ala Asn Ser Val 85 90 95 Val Ala Ile Thr Gln Asn Ser Ile Glu Ser Ala Asp Leu Ala Ala Lys 100 105 110 Ser Ile Gly Ala Asp Arg Val Trp Pro Gly Val Val Arg Gly Phe Phe 115 120 125 Val His Glu Gly Pro Ala Ser Val Ser Tyr Lys Gly Gly Pro Leu Ser 130 135 140 Tyr Thr Phe Gly Asp Ser Gly Glu Leu Ser Arg Gln Phe Ala Ser Thr 145 150 155 160 Leu Glu Gln Ala Gly Ile Asp Gly Val Leu His Pro Asp Ile Leu Val 165 170 175 Asp Val Trp Glu Lys Ala Met Phe Val Glu Val Phe Gly Gly Leu Gly 180 185 190 Ala Phe Val Glu Lys Gln Leu Gly Thr Leu Arg Thr His Phe Arg Ala 195 200 205 Ser Leu Glu Ala Leu Met Glu Glu Val Ala Glu Val Ala Arg Ala Ala 210 215 220 Gly Val Ala Leu Pro Ser Asp Ala Val Glu Arg Thr Met Asn Phe Ala 225 230 235 240 Asp Arg Met Pro Glu Asn Ser Thr Ser Ser Met Gln Arg Asp Leu Ala 245 250 255 Ala Gly Val Ala Ser Glu Leu Glu Ala Gln Thr Gly Ala Ile Val Arg 260 265 270 Ala Ala His Lys Val Gly Val Lys Thr Pro Leu His Asp Leu Ile Tyr 275 280 285 Ala Gly Leu Lys Leu Lys Glu Glu Glu Asn Ser Leu 290 295 300 <210> 631 <211> 408 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(385) <223> RXC02238 <400> 631 ggcgcttagc caaaacatag agcggtaggg tatgcttatc cgattgagca acctttcccg 60 ctcttaacac tactgtccat atacttttga aaaggtgtca gtg acc aac gtg agc 115 Val Thr Asn Val Ser 1 5 aac gag acc aac gcc acc aag gcc gtc ttc gat ccg cca gtg ggc att 163 Asn Glu Thr Asn Ala Thr Lys Ala Val Phe Asp Pro Pro Val Gly Ile 10 15 20 acc gct cct ccg atc gat gaa ctg ctg gat aag gtc act tcc aag tac 211 Thr Ala Pro Pro Ile Asp Glu Leu Leu Asp Lys Val Thr Ser Lys Tyr 25 30 35 gcc ctc gtg atc ttc gca gcc aag cgt gcg cgc cag atc aac agc ttc 259 Ala Leu Val Ile Phe Ala Ala Lys Arg Ala Arg Gln Ile Asn Ser Phe 40 45 50 tac cat cag gca gat gag gga gta ttc gag ttc atc gga cca ttg gtt 307 Tyr His Gln Ala Asp Glu Gly Val Phe Glu Phe Ile Gly Pro Leu Val 55 60 65 act ccg cag cca ggc gaa aag cca ctt tct att gct ctg cgt gag atc 355 Thr Pro Gln Pro Gly Glu Lys Pro Leu Ser Ile Ala Leu Arg Glu Ile 70 75 80 85 aat gca ggt ctg ttg gac cac gag gaa ggt taaaagacct tataacttca 405 Asn Ala Gly Leu Leu Asp His Glu Glu Gly 90 95 cac 408 <210> 632 <211> 95 <212> PRT <213> Corynebacterium glutamicum <400> 632 Val Thr Asn Val Ser Asn Glu Thr Asn Ala Thr Lys Ala Val Phe Asp 1 5 10 15 Pro Pro Val Gly Ile Thr Ala Pro Pro Ile Asp Glu Leu Leu Asp Lys 20 25 30 Val Thr Ser Lys Tyr Ala Leu Val Ile Phe Ala Ala Lys Arg Ala Arg 35 40 45 Gln Ile Asn Ser Phe Tyr His Gln Ala Asp Glu Gly Val Phe Glu Phe 50 55 60 Ile Gly Pro Leu Val Thr Pro Gln Pro Gly Glu Lys Pro Leu Ser Ile 65 70 75 80 Ala Leu Arg Glu Ile Asn Ala Gly Leu Leu Asp His Glu Glu Gly 85 90 95 <210> 633 <211> 606 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(583) <223> RXN03058 <400> 633 acgagcttcc gctctgcaca agccgctaga agccccgcat agccctaatg tagagctcat 60 gcccatttgg aatcacaaca ccgcatatcg gccatggctg gtg tca aag ctc aaa 115 Val Ser Lys Leu Lys 1 5 ggc tca aga tcg ctt ctc gac gtc ggc tcc ggc gat cac tcc ttc gcc 163 Gly Ser Arg Ser Leu Leu Asp Val Gly Ser Gly Asp His Ser Phe Ala 10 15 20 gac ctg gcc ggc cgc cag gtc gcg cat gtc gat gtc gtg gat cct ctt 211 Asp Leu Ala Gly Arg Gln Val Ala His Val Asp Val Val Asp Pro Leu 25 30 35 att aat aca acc ttt gaa gaa ttc cag ccg acc caa agc tac gat gcc 259 Ile Asn Thr Thr Phe Glu Glu Phe Gln Pro Thr Gln Ser Tyr Asp Ala 40 45 50 atc acg ttc atc gcg tcc ctc cat cac atg aac gcg gaa gaa gga ctt 307 Ile Thr Phe Ile Ala Ser Leu His His Met Asn Ala Glu Glu Gly Leu 55 60 65 aac aaa gca gtc cga atc ctc aat cct ggc ggc aag ctc ctc atc gta 355 Asn Lys Ala Val Arg Ile Leu Asn Pro Gly Gly Lys Leu Leu Ile Val 70 75 80 85 ggc ctc gcc aaa aac aaa acc gcc tcc gac tgg atc atc tcc gga cta 403 Gly Leu Ala Lys Asn Lys Thr Ala Ser Asp Trp Ile Ile Ser Gly Leu 90 95 100 caa gct ttt ctc tcc cga cca atc agc ctc atc aat agg gaa caa caa 451 Gln Ala Phe Leu Ser Arg Pro Ile Ser Leu Ile Asn Arg Glu Gln Gln 105 110 115 atc tac ccc ttc cct acc aaa gaa ccc tca gag agt ctc cac gaa ata 499 Ile Tyr Pro Phe Pro Thr Lys Glu Pro Ser Glu Ser Leu His Glu Ile 120 125 130 cga caa ctc acc aag cag ctc ctc cct cac cgc cgt att cgc cgt gga 547 Arg Gln Leu Thr Lys Gln Leu Leu Pro His Arg Arg Ile Arg Arg Gly 135 140 145 atc cac ttc cga tac ctc ctc gag tgg aca aag cct taaacagccc 593 Ile His Phe Arg Tyr Leu Leu Glu Trp Thr Lys Pro 150 155 160 tataaaccaa aaa 606 <210> 634 <211> 161 <212> PRT <213> Corynebacterium glutamicum <400> 634 Val Ser Lys Leu Lys Gly Ser Arg Ser Leu Leu Asp Val Gly Ser Gly 1 5 10 15 Asp His Ser Phe Ala Asp Leu Ala Gly Arg Gln Val Ala His Val Asp 20 25 30 Val Val Asp Pro Leu Ile Asn Thr Thr Phe Glu Glu Phe Gln Pro Thr 35 40 45 Gln Ser Tyr Asp Ala Ile Thr Phe Ile Ala Ser Leu His His Met Asn 50 55 60 Ala Glu Glu Gly Leu Asn Lys Ala Val Arg Ile Leu Asn Pro Gly Gly 65 70 75 80 Lys Leu Leu Ile Val Gly Leu Ala Lys Asn Lys Thr Ala Ser Asp Trp 85 90 95 Ile Ile Ser Gly Leu Gln Ala Phe Leu Ser Arg Pro Ile Ser Leu Ile 100 105 110 Asn Arg Glu Gln Gln Ile Tyr Pro Phe Pro Thr Lys Glu Pro Ser Glu 115 120 125 Ser Leu His Glu Ile Arg Gln Leu Thr Lys Gln Leu Leu Pro His Arg 130 135 140 Arg Ile Arg Arg Gly Ile His Phe Arg Tyr Leu Leu Glu Trp Thr Lys 145 150 155 160 Pro <210> 635 <211> 606 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(583) <223> FRXA02903 <400> 635 acgagcttcc gctctgcaca agccgctaga agccccgcat agccctaatg tagagctcat 60 gcccatttgg aatcacaaca ccgcatatcg gccatggctg gtg tca aag ctc aaa 115 Val Ser Lys Leu Lys 1 5 ggc tca aga tcg ctt ctc gac gtc ggc tcc ggc gat cac tcc ttc gcc 163 Gly Ser Arg Ser Leu Leu Asp Val Gly Ser Gly Asp His Ser Phe Ala 10 15 20 gac ctg gcc ggc cgc cag gtc gcg cat gtc gat gtc gtg gat cct ctt 211 Asp Leu Ala Gly Arg Gln Val Ala His Val Asp Val Val Asp Pro Leu 25 30 35 att aat aca acc ttt gaa gaa ttc cag ccg acc caa agc tac gat gcc 259 Ile Asn Thr Thr Phe Glu Glu Phe Gln Pro Thr Gln Ser Tyr Asp Ala 40 45 50 atc acg ttc atc gcg tcc ctc cat cac atg aac gcg gaa gaa gga ctt 307 Ile Thr Phe Ile Ala Ser Leu His His Met Asn Ala Glu Glu Gly Leu 55 60 65 aac aaa gca gtc cga atc ctc aat cct ggc ggc aag ctc ctc atc gta 355 Asn Lys Ala Val Arg Ile Leu Asn Pro Gly Gly Lys Leu Leu Ile Val 70 75 80 85 ggc ctc gcc aaa aac aaa acc gcc tcc gac tgg atc atc tcc gga cta 403 Gly Leu Ala Lys Asn Lys Thr Ala Ser Asp Trp Ile Ile Ser Gly Leu 90 95 100 caa gct ttt ctc tcc cga cca atc agc ctc atc aat agg gaa caa caa 451 Gln Ala Phe Leu Ser Arg Pro Ile Ser Leu Ile Asn Arg Glu Gln Gln 105 110 115 atc tac ccc ttc cct acc aaa gaa ccc tca gag agt ctc cac gaa ata 499 Ile Tyr Pro Phe Pro Thr Lys Glu Pro Ser Glu Ser Leu His Glu Ile 120 125 130 cga caa ctc acc aag cag ctc ctc cct cac cgc cgt att cgc cgt gga 547 Arg Gln Leu Thr Lys Gln Leu Leu Pro His Arg Arg Ile Arg Arg Gly 135 140 145 atc cac ttc cga tac ctc ctc gag tgg aca aag cct taaacagccc 593 Ile His Phe Arg Tyr Leu Leu Glu Trp Thr Lys Pro 150 155 160 tataaaccaa aaa 606 <210> 636 <211> 161 <212> PRT <213> Corynebacterium glutamicum <400> 636 Val Ser Lys Leu Lys Gly Ser Arg Ser Leu Leu Asp Val Gly Ser Gly 1 5 10 15 Asp His Ser Phe Ala Asp Leu Ala Gly Arg Gln Val Ala His Val Asp 20 25 30 Val Val Asp Pro Leu Ile Asn Thr Thr Phe Glu Glu Phe Gln Pro Thr 35 40 45 Gln Ser Tyr Asp Ala Ile Thr Phe Ile Ala Ser Leu His His Met Asn 50 55 60 Ala Glu Glu Gly Leu Asn Lys Ala Val Arg Ile Leu Asn Pro Gly Gly 65 70 75 80 Lys Leu Leu Ile Val Gly Leu Ala Lys Asn Lys Thr Ala Ser Asp Trp 85 90 95 Ile Ile Ser Gly Leu Gln Ala Phe Leu Ser Arg Pro Ile Ser Leu Ile 100 105 110 Asn Arg Glu Gln Gln Ile Tyr Pro Phe Pro Thr Lys Glu Pro Ser Glu 115 120 125 Ser Leu His Glu Ile Arg Gln Leu Thr Lys Gln Leu Leu Pro His Arg 130 135 140 Arg Ile Arg Arg Gly Ile His Phe Arg Tyr Leu Leu Glu Trp Thr Lys 145 150 155 160 Pro <210> 637 <211> 783 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(760) <223> RXA00166 <400> 637 ggcgtttagc gatcttcaac atcgagcaac cagcgccagc gcttttaccc aaggcagcac 60 gacttatcac gatgtccgac ctggatatcc ggctgaggcc gtg gag tta gcc cgt 115 Val Glu Leu Ala Arg 1 5 ggg ttt ggc cga gtc ctg gat gtc ggt gca ggt acc gga aaa cta acc 163 Gly Phe Gly Arg Val Leu Asp Val Gly Ala Gly Thr Gly Lys Leu Thr 10 15 20 agt gag cta aca gct gat cag gtc cta gcc ctt gat cca agc atg gac 211 Ser Glu Leu Thr Ala Asp Gln Val Leu Ala Leu Asp Pro Ser Met Asp 25 30 35 atg ttg cgg gtg ttt cgc tcc gcg ctt ccg gcg gtt ccc tgc tgg caa 259 Met Leu Arg Val Phe Arg Ser Ala Leu Pro Ala Val Pro Cys Trp Gln 40 45 50 gcg aca gca gaa cac aca gga ata cgt gac aac gcg gtt gat ctg att 307 Ala Thr Ala Glu His Thr Gly Ile Arg Asp Asn Ala Val Asp Leu Ile 55 60 65 acg tgc gca caa acg tgg cat tgg gtt gac gtg acg gct gcc tca gcg 355 Thr Cys Ala Gln Thr Trp His Trp Val Asp Val Thr Ala Ala Ser Ala 70 75 80 85 gaa ttt gat cgg gtg att gca cct gag ggt gca gtc ctg ctc gtg tgg 403 Glu Phe Asp Arg Val Ile Ala Pro Glu Gly Ala Val Leu Leu Val Trp 90 95 100 aat aac ctg gac acc tcc atc gcg tgg gta cac cga ctc agt cgc att 451 Asn Asn Leu Asp Thr Ser Ile Ala Trp Val His Arg Leu Ser Arg Ile 105 110 115 atg cat gcc ggc gat gta ctc aag ccg gga ttc acc cca gaa acc gca 499 Met His Ala Gly Asp Val Leu Lys Pro Gly Phe Thr Pro Glu Thr Ala 120 125 130 gct ccc tgg ata att gat cga gaa att cgc acc acg tgg aat cag cac 547 Ala Pro Trp Ile Ile Asp Arg Glu Ile Arg Thr Thr Trp Asn Gln His 135 140 145 ctc acc cct gaa gaa atc atc cag ctc gct cac acg agg tcc tac tgg 595 Leu Thr Pro Glu Glu Ile Ile Gln Leu Ala His Thr Arg Ser Tyr Trp 150 155 160 165 tta aac gcg tca gag aaa atc aaa gag cgt gtt gat cag aac ctt cag 643 Leu Asn Ala Ser Glu Lys Ile Lys Glu Arg Val Asp Gln Asn Leu Gln 170 175 180 tgg tat ctc tac gag cat ttg ggt ttc agt ccc gac aat cca gtg gaa 691 Trp Tyr Leu Tyr Glu His Leu Gly Phe Ser Pro Asp Asn Pro Val Glu 185 190 195 ctt ccc tat cgc tgt gat gca ttt tta ctt tca cgt tcc ggt acc ctg 739 Leu Pro Tyr Arg Cys Asp Ala Phe Leu Leu Ser Arg Ser Gly Thr Leu 200 205 210 gca ggc aga tct tcc aat ctt taggagccct cgccatgtac ctg 783 Ala Gly Arg Ser Ser Asn Leu 215 220 <210> 638 <211> 220 <212> PRT <213> Corynebacterium glutamicum <400> 638 Val Glu Leu Ala Arg Gly Phe Gly Arg Val Leu Asp Val Gly Ala Gly 1 5 10 15 Thr Gly Lys Leu Thr Ser Glu Leu Thr Ala Asp Gln Val Leu Ala Leu 20 25 30 Asp Pro Ser Met Asp Met Leu Arg Val Phe Arg Ser Ala Leu Pro Ala 35 40 45 Val Pro Cys Trp Gln Ala Thr Ala Glu His Thr Gly Ile Arg Asp Asn 50 55 60 Ala Val Asp Leu Ile Thr Cys Ala Gln Thr Trp His Trp Val Asp Val 65 70 75 80 Thr Ala Ala Ser Ala Glu Phe Asp Arg Val Ile Ala Pro Glu Gly Ala 85 90 95 Val Leu Leu Val Trp Asn Asn Leu Asp Thr Ser Ile Ala Trp Val His 100 105 110 Arg Leu Ser Arg Ile Met His Ala Gly Asp Val Leu Lys Pro Gly Phe 115 120 125 Thr Pro Glu Thr Ala Ala Pro Trp Ile Ile Asp Arg Glu Ile Arg Thr 130 135 140 Thr Trp Asn Gln His Leu Thr Pro Glu Glu Ile Ile Gln Leu Ala His 145 150 155 160 Thr Arg Ser Tyr Trp Leu Asn Ala Ser Glu Lys Ile Lys Glu Arg Val 165 170 175 Asp Gln Asn Leu Gln Trp Tyr Leu Tyr Glu His Leu Gly Phe Ser Pro 180 185 190 Asp Asn Pro Val Glu Leu Pro Tyr Arg Cys Asp Ala Phe Leu Leu Ser 195 200 205 Arg Ser Gly Thr Leu Ala Gly Arg Ser Ser Asn Leu 210 215 220 <210> 639 <211> 1392 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1369) <223> RXA00633 <400> 639 aaagctgcgg taattaaaaa cacttagcgc caaaaattga acactgttca attaacctat 60 tacactgcag atatacatcc aaaccaagtg acggaggaaa atg gaa aac ccc agc 115 Met Glu Asn Pro Ser 1 5 ttg cgc gag ctt gat cac cga aac atc tgg cac ccg tat gcc gcg ccg 163 Leu Arg Glu Leu Asp His Arg Asn Ile Trp His Pro Tyr Ala Ala Pro 10 15 20 ggc gtg cgc aat aga ctc gtc acc aaa acc gat gga gtg ttt ttg acg 211 Gly Val Arg Asn Arg Leu Val Thr Lys Thr Asp Gly Val Phe Leu Thr 25 30 35 ctg gaa gat ggc agc acc gtg att gac gcg atg agc tcc tgg tgg tcg 259 Leu Glu Asp Gly Ser Thr Val Ile Asp Ala Met Ser Ser Trp Trp Ser 40 45 50 gca att cat gga cac gga cac ccc cga ctg aaa gct gcc gcc caa aaa 307 Ala Ile His Gly His Gly His Pro Arg Leu Lys Ala Ala Ala Gln Lys 55 60 65 caa atc gac acc atg agt cac gtc atg ttt ggc gga cta acc cac gag 355 Gln Ile Asp Thr Met Ser His Val Met Phe Gly Gly Leu Thr His Glu 70 75 80 85 ccc gcc att aag ctc acc cac aaa ctc ctc aat ctc act gga aat tcc 403 Pro Ala Ile Lys Leu Thr His Lys Leu Leu Asn Leu Thr Gly Asn Ser 90 95 100 ttt gac cac gtc ttt tat tcc gat tcg ggc tcg gtc tca gtg gag gtc 451 Phe Asp His Val Phe Tyr Ser Asp Ser Gly Ser Val Ser Val Glu Val 105 110 115 gcc atc aaa atg gca ctg cag gcc tcc aaa gga caa ggc cac ccg gaa 499 Ala Ile Lys Met Ala Leu Gln Ala Ser Lys Gly Gln Gly His Pro Glu 120 125 130 cgg aca aaa ctc ctc acc tgg cgg tcc ggc tac cac gga gac aca ttc 547 Arg Thr Lys Leu Leu Thr Trp Arg Ser Gly Tyr His Gly Asp Thr Phe 135 140 145 acc gcg atg agc gtg tgc gac cca gaa aat ggc atg cat agc ctc tgg 595 Thr Ala Met Ser Val Cys Asp Pro Glu Asn Gly Met His Ser Leu Trp 150 155 160 165 aaa ggc aca ctc ccc gag cag att ttc gcc ccc gcc cca cca gtt cgg 643 Lys Gly Thr Leu Pro Glu Gln Ile Phe Ala Pro Ala Pro Pro Val Arg 170 175 180 ggg tca tcg ccg cag gcg att tcc gag tac ctg cgc agc atg gaa ttg 691 Gly Ser Ser Pro Gln Ala Ile Ser Glu Tyr Leu Arg Ser Met Glu Leu 185 190 195 ctt atc gac gag gcg gtc tcc gca atc atc atc gaa ccg atc gtc caa 739 Leu Ile Asp Glu Ala Val Ser Ala Ile Ile Ile Glu Pro Ile Val Gln 200 205 210 ggc gct gga ggc atg cgc ttt cac gat gtc gca ctc att gaa gga gtc 787 Gly Ala Gly Gly Met Arg Phe His Asp Val Ala Leu Ile Glu Gly Val 215 220 225 gcc aca ctg tgc aag aag cac gat cgt ttc ttg atc gtc gat gaa att 835 Ala Thr Leu Cys Lys Lys His Asp Arg Phe Leu Ile Val Asp Glu Ile 230 235 240 245 gcc act ggt ttc ggc cgc acc ggt gaa cta ttt gcc acg tta agc aat 883 Ala Thr Gly Phe Gly Arg Thr Gly Glu Leu Phe Ala Thr Leu Ser Asn 250 255 260 ggc cta caa cca gac atc atg tgt gtg ggc aag gcc ctc acc ggt gga 931 Gly Leu Gln Pro Asp Ile Met Cys Val Gly Lys Ala Leu Thr Gly Gly 265 270 275 ttc atg tcc ttc gcc gct act tta tgc acg gac aag gtg gct caa tta 979 Phe Met Ser Phe Ala Ala Thr Leu Cys Thr Asp Lys Val Ala Gln Leu 280 285 290 atc agc acc cca aat ggc gga ggt gcg ctg atg cac ggc ccc act ttt 1027 Ile Ser Thr Pro Asn Gly Gly Gly Ala Leu Met His Gly Pro Thr Phe 295 300 305 atg gct aat cct ctg gcc tgt gcg gtt tcg cat gct tca tta gaa atc 1075 Met Ala Asn Pro Leu Ala Cys Ala Val Ser His Ala Ser Leu Glu Ile 310 315 320 325 att gag acc ggc atg tgg cag aaa cag gta aaa aga atc gaa gcc gaa 1123 Ile Glu Thr Gly Met Trp Gln Lys Gln Val Lys Arg Ile Glu Ala Glu 330 335 340 ctt atc gca ggc ctt tcc cca ctt caa cac ctt cca ggg gtt gcc gat 1171 Leu Ile Ala Gly Leu Ser Pro Leu Gln His Leu Pro Gly Val Ala Asp 345 350 355 gtc cgg gtt ctc ggc gcg att ggt gtc atc gaa atg gaa caa aat gtc 1219 Val Arg Val Leu Gly Ala Ile Gly Val Ile Glu Met Glu Gln Asn Val 360 365 370 aat gtc gaa gaa gct act cag gct gca tta gat cac ggt gtg tgg atc 1267 Asn Val Glu Glu Ala Thr Gln Ala Ala Leu Asp His Gly Val Trp Ile 375 380 385 cgc ccc ttt gga cgc ttg ctc tat gtc atg cct cca tat atc acc acg 1315 Arg Pro Phe Gly Arg Leu Leu Tyr Val Met Pro Pro Tyr Ile Thr Thr 390 395 400 405 tca gag cag tgc gca cag atc tgc act gcg ctt cat gct gca gtt aaa 1363 Ser Glu Gln Cys Ala Gln Ile Cys Thr Ala Leu His Ala Ala Val Lys 410 415 420 ggg aaa taaaccatgc catttttatt tgt 1392 Gly Lys <210> 640 <211> 423 <212> PRT <213> Corynebacterium glutamicum <400> 640 Met Glu Asn Pro Ser Leu Arg Glu Leu Asp His Arg Asn Ile Trp His 1 5 10 15 Pro Tyr Ala Ala Pro Gly Val Arg Asn Arg Leu Val Thr Lys Thr Asp 20 25 30 Gly Val Phe Leu Thr Leu Glu Asp Gly Ser Thr Val Ile Asp Ala Met 35 40 45 Ser Ser Trp Trp Ser Ala Ile His Gly His Gly His Pro Arg Leu Lys 50 55 60 Ala Ala Ala Gln Lys Gln Ile Asp Thr Met Ser His Val Met Phe Gly 65 70 75 80 Gly Leu Thr His Glu Pro Ala Ile Lys Leu Thr His Lys Leu Leu Asn 85 90 95 Leu Thr Gly Asn Ser Phe Asp His Val Phe Tyr Ser Asp Ser Gly Ser 100 105 110 Val Ser Val Glu Val Ala Ile Lys Met Ala Leu Gln Ala Ser Lys Gly 115 120 125 Gln Gly His Pro Glu Arg Thr Lys Leu Leu Thr Trp Arg Ser Gly Tyr 130 135 140 His Gly Asp Thr Phe Thr Ala Met Ser Val Cys Asp Pro Glu Asn Gly 145 150 155 160 Met His Ser Leu Trp Lys Gly Thr Leu Pro Glu Gln Ile Phe Ala Pro 165 170 175 Ala Pro Pro Val Arg Gly Ser Ser Pro Gln Ala Ile Ser Glu Tyr Leu 180 185 190 Arg Ser Met Glu Leu Leu Ile Asp Glu Ala Val Ser Ala Ile Ile Ile 195 200 205 Glu Pro Ile Val Gln Gly Ala Gly Gly Met Arg Phe His Asp Val Ala 210 215 220 Leu Ile Glu Gly Val Ala Thr Leu Cys Lys Lys His Asp Arg Phe Leu 225 230 235 240 Ile Val Asp Glu Ile Ala Thr Gly Phe Gly Arg Thr Gly Glu Leu Phe 245 250 255 Ala Thr Leu Ser Asn Gly Leu Gln Pro Asp Ile Met Cys Val Gly Lys 260 265 270 Ala Leu Thr Gly Gly Phe Met Ser Phe Ala Ala Thr Leu Cys Thr Asp 275 280 285 Lys Val Ala Gln Leu Ile Ser Thr Pro Asn Gly Gly Gly Ala Leu Met 290 295 300 His Gly Pro Thr Phe Met Ala Asn Pro Leu Ala Cys Ala Val Ser His 305 310 315 320 Ala Ser Leu Glu Ile Ile Glu Thr Gly Met Trp Gln Lys Gln Val Lys 325 330 335 Arg Ile Glu Ala Glu Leu Ile Ala Gly Leu Ser Pro Leu Gln His Leu 340 345 350 Pro Gly Val Ala Asp Val Arg Val Leu Gly Ala Ile Gly Val Ile Glu 355 360 365 Met Glu Gln Asn Val Asn Val Glu Glu Ala Thr Gln Ala Ala Leu Asp 370 375 380 His Gly Val Trp Ile Arg Pro Phe Gly Arg Leu Leu Tyr Val Met Pro 385 390 395 400 Pro Tyr Ile Thr Thr Ser Glu Gln Cys Ala Gln Ile Cys Thr Ala Leu 405 410 415 His Ala Ala Val Lys Gly Lys 420 <210> 641 <211> 795 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(772) <223> RXA00632 <400> 641 tggacgcttg ctctatgtca tgcctccata tatcaccacg tcagagcagt gcgcacagat 60 ctgcactgcg cttcatgctg cagttaaagg gaaataaacc atg cca ttt tta ttt 115 Met Pro Phe Leu Phe 1 5 gtc agc ggt acc gga act ggg gtt ggg aaa acc ttc tcc aca gcc gtt 163 Val Ser Gly Thr Gly Thr Gly Val Gly Lys Thr Phe Ser Thr Ala Val 10 15 20 ttg gtt cga tac tta gcc gat caa gga cac gat gtt ctg ccc gta aag 211 Leu Val Arg Tyr Leu Ala Asp Gln Gly His Asp Val Leu Pro Val Lys 25 30 35 cta gtc caa acc ggt gaa ctt cca ggc gag gga gac atc ttt aac att 259 Leu Val Gln Thr Gly Glu Leu Pro Gly Glu Gly Asp Ile Phe Asn Ile 40 45 50 gaa cgc ttg act gga att gct gga gag gaa ttt gct cgt ttc aaa gac 307 Glu Arg Leu Thr Gly Ile Ala Gly Glu Glu Phe Ala Arg Phe Lys Asp 55 60 65 cct ctt gcg cca aat ctg gca gcc cga cga gag ggg gtc gag cca ata 355 Pro Leu Ala Pro Asn Leu Ala Ala Arg Arg Glu Gly Val Glu Pro Ile 70 75 80 85 cag ttt gat cag att atc tcg tgg ctt cgt ggt ttt gac gac cca gat 403 Gln Phe Asp Gln Ile Ile Ser Trp Leu Arg Gly Phe Asp Asp Pro Asp 90 95 100 cgc atc att gtg gtg gag ggc gct ggt ggc ctg ctg gtc aga tta ggg 451 Arg Ile Ile Val Val Glu Gly Ala Gly Gly Leu Leu Val Arg Leu Gly 105 110 115 gaa gat ttc acc ctg gca gat gtt gcc tcc gct ttg aat gca ccc tta 499 Glu Asp Phe Thr Leu Ala Asp Val Ala Ser Ala Leu Asn Ala Pro Leu 120 125 130 gtg att gtg aca agc acc gga ttg gga agc ctc aac gct gct gaa tta 547 Val Ile Val Thr Ser Thr Gly Leu Gly Ser Leu Asn Ala Ala Glu Leu 135 140 145 agc gtt gag gca gca aac cgc cga gga ctc aca gtg ttg gga gtc ctc 595 Ser Val Glu Ala Ala Asn Arg Arg Gly Leu Thr Val Leu Gly Val Leu 150 155 160 165 ggc ggt tcg atc cct caa aat cct gat cta gct acg atg ctt aat ctc 643 Gly Gly Ser Ile Pro Gln Asn Pro Asp Leu Ala Thr Met Leu Asn Leu 170 175 180 gaa gaa ttt gag aga gtc acc ggc gtg ccc ttt tgg gga gct ttg ccg 691 Glu Glu Phe Glu Arg Val Thr Gly Val Pro Phe Trp Gly Ala Leu Pro 185 190 195 gaa ggg ttg tca cgg gtg gag ggg ttc gtc gaa aag caa tct ttt ccg 739 Glu Gly Leu Ser Arg Val Glu Gly Phe Val Glu Lys Gln Ser Phe Pro 200 205 210 gcc ctt gat gcc ttt aag aaa ccg ccg gca agg tgatcgtgaa caccgtgcct 792 Ala Leu Asp Ala Phe Lys Lys Pro Pro Ala Arg 215 220 tcg 795 <210> 642 <211> 224 <212> PRT <213> Corynebacterium glutamicum <400> 642 Met Pro Phe Leu Phe Val Ser Gly Thr Gly Thr Gly Val Gly Lys Thr 1 5 10 15 Phe Ser Thr Ala Val Leu Val Arg Tyr Leu Ala Asp Gln Gly His Asp 20 25 30 Val Leu Pro Val Lys Leu Val Gln Thr Gly Glu Leu Pro Gly Glu Gly 35 40 45 Asp Ile Phe Asn Ile Glu Arg Leu Thr Gly Ile Ala Gly Glu Glu Phe 50 55 60 Ala Arg Phe Lys Asp Pro Leu Ala Pro Asn Leu Ala Ala Arg Arg Glu 65 70 75 80 Gly Val Glu Pro Ile Gln Phe Asp Gln Ile Ile Ser Trp Leu Arg Gly 85 90 95 Phe Asp Asp Pro Asp Arg Ile Ile Val Val Glu Gly Ala Gly Gly Leu 100 105 110 Leu Val Arg Leu Gly Glu Asp Phe Thr Leu Ala Asp Val Ala Ser Ala 115 120 125 Leu Asn Ala Pro Leu Val Ile Val Thr Ser Thr Gly Leu Gly Ser Leu 130 135 140 Asn Ala Ala Glu Leu Ser Val Glu Ala Ala Asn Arg Arg Gly Leu Thr 145 150 155 160 Val Leu Gly Val Leu Gly Gly Ser Ile Pro Gln Asn Pro Asp Leu Ala 165 170 175 Thr Met Leu Asn Leu Glu Glu Phe Glu Arg Val Thr Gly Val Pro Phe 180 185 190 Trp Gly Ala Leu Pro Glu Gly Leu Ser Arg Val Glu Gly Phe Val Glu 195 200 205 Lys Gln Ser Phe Pro Ala Leu Asp Ala Phe Lys Lys Pro Pro Ala Arg 210 215 220 <210> 643 <211> 1125 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1102) <223> RXA00295 <400> 643 gtttaaggca cgtgtcattt tgcatgcgcg tgcccaattc ttcttaagtg tgctcaattt 60 ttaagcgcgc agttattgac aaccagcctc taggagatcc atg acc atc ccc ggc 115 Met Thr Ile Pro Gly 1 5 acc atc ctt gac acc gcc cgc acc caa gtt ctg gaa cag gga att ggc 163 Thr Ile Leu Asp Thr Ala Arg Thr Gln Val Leu Glu Gln Gly Ile Gly 10 15 20 ctt aat cag cag cag ttg atg gag gtt ctc acc ttg cct gaa gag caa 211 Leu Asn Gln Gln Gln Leu Met Glu Val Leu Thr Leu Pro Glu Glu Gln 25 30 35 atc cca gac ttg atg gaa tta gcc cac cag gtt cgg ttg aag tgg tgt 259 Ile Pro Asp Leu Met Glu Leu Ala His Gln Val Arg Leu Lys Trp Cys 40 45 50 ggg gaa gaa atc gag gtc gag ggc att att tcc ctc aaa act ggc ggt 307 Gly Glu Glu Ile Glu Val Glu Gly Ile Ile Ser Leu Lys Thr Gly Gly 55 60 65 tgc cct gaa gat tgt cat ttc tgc tca cag tct ggg ttg ttt gaa tcg 355 Cys Pro Glu Asp Cys His Phe Cys Ser Gln Ser Gly Leu Phe Glu Ser 70 75 80 85 ccg gtg cgt tcg gtg tgg ctg gat att ccg aat ctg gtt gaa gcc gct 403 Pro Val Arg Ser Val Trp Leu Asp Ile Pro Asn Leu Val Glu Ala Ala 90 95 100 aaa cag acc gca aaa act ggc gct acc gaa ttc tgt atc gtc gcc gca 451 Lys Gln Thr Ala Lys Thr Gly Ala Thr Glu Phe Cys Ile Val Ala Ala 105 110 115 gtc aag ggg cct gat gag agg ctc atg acc cag ctg gag gaa gca gtc 499 Val Lys Gly Pro Asp Glu Arg Leu Met Thr Gln Leu Glu Glu Ala Val 120 125 130 ctc gcg att cac tct gaa gtt gaa att gaa gtc gca gca tcg atc gga 547 Leu Ala Ile His Ser Glu Val Glu Ile Glu Val Ala Ala Ser Ile Gly 135 140 145 acg tta aat aag gaa cag gtg gat cgc ctc gct gct gcc ggc gtg cac 595 Thr Leu Asn Lys Glu Gln Val Asp Arg Leu Ala Ala Ala Gly Val His 150 155 160 165 cgc tac aac cat aat ttg gaa act gcg cgt tcc tat ttc cct gaa gtt 643 Arg Tyr Asn His Asn Leu Glu Thr Ala Arg Ser Tyr Phe Pro Glu Val 170 175 180 gtc acc act cat aca tgg gaa gag cgc cgc gaa act ttg cgc ctg gtg 691 Val Thr Thr His Thr Trp Glu Glu Arg Arg Glu Thr Leu Arg Leu Val 185 190 195 gca gaa gct gga atg gaa gtc tgt tcc ggc gga atc tta gga atg ggc 739 Ala Glu Ala Gly Met Glu Val Cys Ser Gly Gly Ile Leu Gly Met Gly 200 205 210 gaa act tta gag cag cgc gcc gag ttt gcc gtg cag ctg gcg gag ctt 787 Glu Thr Leu Glu Gln Arg Ala Glu Phe Ala Val Gln Leu Ala Glu Leu 215 220 225 gat ccg cac gaa gtc ccc atg aac ttc ctt gat cct cgc ccg ggc acc 835 Asp Pro His Glu Val Pro Met Asn Phe Leu Asp Pro Arg Pro Gly Thr 230 235 240 245 cca ttt gcc gat agg gaa ttg atg gac agc cgt gac gct ctg cgc tct 883 Pro Phe Ala Asp Arg Glu Leu Met Asp Ser Arg Asp Ala Leu Arg Ser 250 255 260 att ggt gcg ttc cgc ctt gcg atg cct cac acc atg ctt cgt ttt gct 931 Ile Gly Ala Phe Arg Leu Ala Met Pro His Thr Met Leu Arg Phe Ala 265 270 275 ggc ggt cgc gag ctg act ttg ggc gac aag ggt tcc gag caa gcc ctc 979 Gly Gly Arg Glu Leu Thr Leu Gly Asp Lys Gly Ser Glu Gln Ala Leu 280 285 290 ctg gga ggc atc aat gcg atg atc gtc gga aac tac ctg act acg ctc 1027 Leu Gly Gly Ile Asn Ala Met Ile Val Gly Asn Tyr Leu Thr Thr Leu 295 300 305 ggc cgc cca atg gaa gat gac ctc gac atg atg gat cgt ctc cag ctg 1075 Gly Arg Pro Met Glu Asp Asp Leu Asp Met Met Asp Arg Leu Gln Leu 310 315 320 325 ccc atc aaa gtc ctt aat aag gtc atc taagaagcac gcgcatgaac 1122 Pro Ile Lys Val Leu Asn Lys Val Ile 330 gac 1125 <210> 644 <211> 334 <212> PRT <213> Corynebacterium glutamicum <400> 644 Met Thr Ile Pro Gly Thr Ile Leu Asp Thr Ala Arg Thr Gln Val Leu 1 5 10 15 Glu Gln Gly Ile Gly Leu Asn Gln Gln Gln Leu Met Glu Val Leu Thr 20 25 30 Leu Pro Glu Glu Gln Ile Pro Asp Leu Met Glu Leu Ala His Gln Val 35 40 45 Arg Leu Lys Trp Cys Gly Glu Glu Ile Glu Val Glu Gly Ile Ile Ser 50 55 60 Leu Lys Thr Gly Gly Cys Pro Glu Asp Cys His Phe Cys Ser Gln Ser 65 70 75 80 Gly Leu Phe Glu Ser Pro Val Arg Ser Val Trp Leu Asp Ile Pro Asn 85 90 95 Leu Val Glu Ala Ala Lys Gln Thr Ala Lys Thr Gly Ala Thr Glu Phe 100 105 110 Cys Ile Val Ala Ala Val Lys Gly Pro Asp Glu Arg Leu Met Thr Gln 115 120 125 Leu Glu Glu Ala Val Leu Ala Ile His Ser Glu Val Glu Ile Glu Val 130 135 140 Ala Ala Ser Ile Gly Thr Leu Asn Lys Glu Gln Val Asp Arg Leu Ala 145 150 155 160 Ala Ala Gly Val His Arg Tyr Asn His Asn Leu Glu Thr Ala Arg Ser 165 170 175 Tyr Phe Pro Glu Val Val Thr Thr His Thr Trp Glu Glu Arg Arg Glu 180 185 190 Thr Leu Arg Leu Val Ala Glu Ala Gly Met Glu Val Cys Ser Gly Gly 195 200 205 Ile Leu Gly Met Gly Glu Thr Leu Glu Gln Arg Ala Glu Phe Ala Val 210 215 220 Gln Leu Ala Glu Leu Asp Pro His Glu Val Pro Met Asn Phe Leu Asp 225 230 235 240 Pro Arg Pro Gly Thr Pro Phe Ala Asp Arg Glu Leu Met Asp Ser Arg 245 250 255 Asp Ala Leu Arg Ser Ile Gly Ala Phe Arg Leu Ala Met Pro His Thr 260 265 270 Met Leu Arg Phe Ala Gly Gly Arg Glu Leu Thr Leu Gly Asp Lys Gly 275 280 285 Ser Glu Gln Ala Leu Leu Gly Gly Ile Asn Ala Met Ile Val Gly Asn 290 295 300 Tyr Leu Thr Thr Leu Gly Arg Pro Met Glu Asp Asp Leu Asp Met Met 305 310 315 320 Asp Arg Leu Gln Leu Pro Ile Lys Val Leu Asn Lys Val Ile 325 330 <210> 645 <211> 1212 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1189) <223> RXA00223 <400> 645 gcgacctctt tgacatcgcc cctgcgctca tcgaagagat caacaagcgc aagtaggagt 60 tttgaacact ttttatctgg accatgcagc caccacacca atg cgt gag gtg gcc 115 Met Arg Glu Val Ala 1 5 gca gct gcg tgg atg gaa aac gcg cag gca ttg aat ccc gcg agt cag 163 Ala Ala Ala Trp Met Glu Asn Ala Gln Ala Leu Asn Pro Ala Ser Gln 10 15 20 tac ggt tcg ggg cgt aag gcg cgc agc gtt gcg gat tcg gct cgt gaa 211 Tyr Gly Ser Gly Arg Lys Ala Arg Ser Val Ala Asp Ser Ala Arg Glu 25 30 35 gaa att gct tct ttg ctg ggc tgt gaa cct atc gag gtt gtg ttt acc 259 Glu Ile Ala Ser Leu Leu Gly Cys Glu Pro Ile Glu Val Val Phe Thr 40 45 50 gcg tcc ggc acg gag gca gat aac ctc gct gtg cag ggg tta ttc cac 307 Ala Ser Gly Thr Glu Ala Asp Asn Leu Ala Val Gln Gly Leu Phe His 55 60 65 gca tcg cct ctc aat cgg att att tct acg ccg atc gag cac ccc ggg 355 Ala Ser Pro Leu Asn Arg Ile Ile Ser Thr Pro Ile Glu His Pro Gly 70 75 80 85 att ctg gaa acc gtc aag gct cta gaa ctt ggc ggg gca gag gcg gag 403 Ile Leu Glu Thr Val Lys Ala Leu Glu Leu Gly Gly Ala Glu Ala Glu 90 95 100 ctc atg ccg atc ggt cca gat gga cga gtg tct tcc ttc gaa gcg ctg 451 Leu Met Pro Ile Gly Pro Asp Gly Arg Val Ser Ser Phe Glu Ala Leu 105 110 115 gac aag cct gcc gcg gtt gcc act atg atg tgg gcg aac aat gag acc 499 Asp Lys Pro Ala Ala Val Ala Thr Met Met Trp Ala Asn Asn Glu Thr 120 125 130 ggc gcg att cag ccg gtt tct gag ttc atc gcc gcc gcg cag gcg tcc 547 Gly Ala Ile Gln Pro Val Ser Glu Phe Ile Ala Ala Ala Gln Ala Ser 135 140 145 ggc acg cca aca cac atc gat gcg gtt cag gtc gtt ggc cat ctg ccg 595 Gly Thr Pro Thr His Ile Asp Ala Val Gln Val Val Gly His Leu Pro 150 155 160 165 gtc aat ttt gat gag ctc ggc gcc acc act ttg gct gcc tcc gcg cac 643 Val Asn Phe Asp Glu Leu Gly Ala Thr Thr Leu Ala Ala Ser Ala His 170 175 180 aaa ttc ggt gga cca cgt ggc gtc ggc ctg ctg ttg gtg agg cgc tca 691 Lys Phe Gly Gly Pro Arg Gly Val Gly Leu Leu Leu Val Arg Arg Ser 185 190 195 cca gca cct tca gcc gta ttg cac gga ggt ggt cag gag cgc ggc atc 739 Pro Ala Pro Ser Ala Val Leu His Gly Gly Gly Gln Glu Arg Gly Ile 200 205 210 cgt cca ggc acc ctt gat gtc gcc ggc gca gct gcc acc gca gcc gca 787 Arg Pro Gly Thr Leu Asp Val Ala Gly Ala Ala Ala Thr Ala Ala Ala 215 220 225 tta cgc gaa gca gtg gcc gag ctt gac ggc gaa gcc acc cgc ctg cgc 835 Leu Arg Glu Ala Val Ala Glu Leu Asp Gly Glu Ala Thr Arg Leu Arg 230 235 240 245 gga ctt aaa aag atg ctt ctc gac gcc atc ctc cac acc atc ccc aac 883 Gly Leu Lys Lys Met Leu Leu Asp Ala Ile Leu His Thr Ile Pro Asn 250 255 260 gta ctg gtc cac acc acc gaa cca tcc ctg cca gga cac ctg cat ctc 931 Val Leu Val His Thr Thr Glu Pro Ser Leu Pro Gly His Leu His Leu 265 270 275 tcc ttc cca gga gca gaa ggc gat agt ttg atc atg ctg ctc gac tcc 979 Ser Phe Pro Gly Ala Glu Gly Asp Ser Leu Ile Met Leu Leu Asp Ser 280 285 290 ttg cgg atc gaa gcc tcc aca ggt tcg gcc tgc tcc aac ggt gta aac 1027 Leu Arg Ile Glu Ala Ser Thr Gly Ser Ala Cys Ser Asn Gly Val Asn 295 300 305 cgt gcc agc cac gtc ctt ttg gcc atg gga att tcc gaa acc gac gcc 1075 Arg Ala Ser His Val Leu Leu Ala Met Gly Ile Ser Glu Thr Asp Ala 310 315 320 325 cgt ggt gcc atc cga ttc acc ctc gga aga acc acc act gaa gaa tcc 1123 Arg Gly Ala Ile Arg Phe Thr Leu Gly Arg Thr Thr Thr Glu Glu Ser 330 335 340 atc aag gca gtg atc gcc gtg atc gaa gac gta gtg acc agg gct cgt 1171 Ile Lys Ala Val Ile Ala Val Ile Glu Asp Val Val Thr Arg Ala Arg 345 350 355 act gcg gga atg gct ttt tagcgaccgt aaatcgcata gtg 1212 Thr Ala Gly Met Ala Phe 360 <210> 646 <211> 363 <212> PRT <213> Corynebacterium glutamicum <400> 646 Met Arg Glu Val Ala Ala Ala Ala Trp Met Glu Asn Ala Gln Ala Leu 1 5 10 15 Asn Pro Ala Ser Gln Tyr Gly Ser Gly Arg Lys Ala Arg Ser Val Ala 20 25 30 Asp Ser Ala Arg Glu Glu Ile Ala Ser Leu Leu Gly Cys Glu Pro Ile 35 40 45 Glu Val Val Phe Thr Ala Ser Gly Thr Glu Ala Asp Asn Leu Ala Val 50 55 60 Gln Gly Leu Phe His Ala Ser Pro Leu Asn Arg Ile Ile Ser Thr Pro 65 70 75 80 Ile Glu His Pro Gly Ile Leu Glu Thr Val Lys Ala Leu Glu Leu Gly 85 90 95 Gly Ala Glu Ala Glu Leu Met Pro Ile Gly Pro Asp Gly Arg Val Ser 100 105 110 Ser Phe Glu Ala Leu Asp Lys Pro Ala Ala Val Ala Thr Met Met Trp 115 120 125 Ala Asn Asn Glu Thr Gly Ala Ile Gln Pro Val Ser Glu Phe Ile Ala 130 135 140 Ala Ala Gln Ala Ser Gly Thr Pro Thr His Ile Asp Ala Val Gln Val 145 150 155 160 Val Gly His Leu Pro Val Asn Phe Asp Glu Leu Gly Ala Thr Thr Leu 165 170 175 Ala Ala Ser Ala His Lys Phe Gly Gly Pro Arg Gly Val Gly Leu Leu 180 185 190 Leu Val Arg Arg Ser Pro Ala Pro Ser Ala Val Leu His Gly Gly Gly 195 200 205 Gln Glu Arg Gly Ile Arg Pro Gly Thr Leu Asp Val Ala Gly Ala Ala 210 215 220 Ala Thr Ala Ala Ala Leu Arg Glu Ala Val Ala Glu Leu Asp Gly Glu 225 230 235 240 Ala Thr Arg Leu Arg Gly Leu Lys Lys Met Leu Leu Asp Ala Ile Leu 245 250 255 His Thr Ile Pro Asn Val Leu Val His Thr Thr Glu Pro Ser Leu Pro 260 265 270 Gly His Leu His Leu Ser Phe Pro Gly Ala Glu Gly Asp Ser Leu Ile 275 280 285 Met Leu Leu Asp Ser Leu Arg Ile Glu Ala Ser Thr Gly Ser Ala Cys 290 295 300 Ser Asn Gly Val Asn Arg Ala Ser His Val Leu Leu Ala Met Gly Ile 305 310 315 320 Ser Glu Thr Asp Ala Arg Gly Ala Ile Arg Phe Thr Leu Gly Arg Thr 325 330 335 Thr Thr Glu Glu Ser Ile Lys Ala Val Ile Ala Val Ile Glu Asp Val 340 345 350 Val Thr Arg Ala Arg Thr Ala Gly Met Ala Phe 355 360 <210> 647 <211> 1197 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1174) <223> RXN00262 <400> 647 acaccgcggg aaagattgca tcaaccggtg tcgacgtcat ttccgttgga gcgcttaccc 60 attctgtgca tgcacttgac ctaggactcg atattttcta atg ctc tac ctt gat 115 Met Leu Tyr Leu Asp 1 5 aat gca gcc acc acc agt gtg cgc aat gaa gca ctt gag gcc atg tgg 163 Asn Ala Ala Thr Thr Ser Val Arg Asn Glu Ala Leu Glu Ala Met Trp 10 15 20 cct tat ctc acc gga gcg ttt ggc aat ccg tca agt ccc cat gag gtg 211 Pro Tyr Leu Thr Gly Ala Phe Gly Asn Pro Ser Ser Pro His Glu Val 25 30 35 gga aga ctc gcc tct gcg ggg ctg gag gat gct cga act cgg gtg gcc 259 Gly Arg Leu Ala Ser Ala Gly Leu Glu Asp Ala Arg Thr Arg Val Ala 40 45 50 cgc att atc gga gga cgc ccc aca cag gtg acg ttt acg tcg ggt gga 307 Arg Ile Ile Gly Gly Arg Pro Thr Gln Val Thr Phe Thr Ser Gly Gly 55 60 65 tca gaa gcc aac aac ctc gct atc aaa gga gcg tgc tta gct aat cct 355 Ser Glu Ala Asn Asn Leu Ala Ile Lys Gly Ala Cys Leu Ala Asn Pro 70 75 80 85 cgt ggc cgg cac ctc atc acc acc ccg atc gag cat gac agt gtc cta 403 Arg Gly Arg His Leu Ile Thr Thr Pro Ile Glu His Asp Ser Val Leu 90 95 100 gaa act gct gct tat ctt gaa agg ttt cat gat ttc gag atc acc tac 451 Glu Thr Ala Ala Tyr Leu Glu Arg Phe His Asp Phe Glu Ile Thr Tyr 105 110 115 cta tcc ccc gat cac act ggg ctg atc tcc ccg gag ggt ctc cgc aaa 499 Leu Ser Pro Asp His Thr Gly Leu Ile Ser Pro Glu Gly Leu Arg Lys 120 125 130 gca gtc agg ccg gac acc aca ttg atc agc att ggt tat gcc aac aat 547 Ala Val Arg Pro Asp Thr Thr Leu Ile Ser Ile Gly Tyr Ala Asn Asn 135 140 145 gag gtg gga acc att cag ccg ata gct gag ttg gcg gcg gta agc agt 595 Glu Val Gly Thr Ile Gln Pro Ile Ala Glu Leu Ala Ala Val Ser Ser 150 155 160 165 acg cct ttt cac acc gat gca gtg caa gct gca cat tta acc ttt gac 643 Thr Pro Phe His Thr Asp Ala Val Gln Ala Ala His Leu Thr Phe Asp 170 175 180 ttg gga gtt gac gcg tta agt ttg tcg ggt cat aaa ttc ggt gcg cct 691 Leu Gly Val Asp Ala Leu Ser Leu Ser Gly His Lys Phe Gly Ala Pro 185 190 195 aaa ggg att gga gtg tta tgg tca aag ctt ccc ctg gag ccg gta atc 739 Lys Gly Ile Gly Val Leu Trp Ser Lys Leu Pro Leu Glu Pro Val Ile 200 205 210 cat ggc ggc ggc cag gaa aaa ggg cgg cgt agt ggc acg gaa aac gtt 787 His Gly Gly Gly Gln Glu Lys Gly Arg Arg Ser Gly Thr Glu Asn Val 215 220 225 gcg ggg gct atc gcc ttt gcc act gcc ttg gaa ttg gcc agg gcg gaa 835 Ala Gly Ala Ile Ala Phe Ala Thr Ala Leu Glu Leu Ala Arg Ala Glu 230 235 240 245 tcc tat cca gat ctt ggc gaa ttc atc gag gaa gtt ctc act atc ccg 883 Ser Tyr Pro Asp Leu Gly Glu Phe Ile Glu Glu Val Leu Thr Ile Pro 250 255 260 gga gca cac ctg act gga cat cct agg atg cgc att gat gga cac gca 931 Gly Ala His Leu Thr Gly His Pro Arg Met Arg Ile Asp Gly His Ala 265 270 275 tct ttt ctc ttc gac agc ata gga tct gaa act gtt ctt ctg gaa ttg 979 Ser Phe Leu Phe Asp Ser Ile Gly Ser Glu Thr Val Leu Leu Glu Leu 280 285 290 gaa cgc caa ggc att gtg tgc tcc cct ggt tct gcc tgt ggt tcc gga 1027 Glu Arg Gln Gly Ile Val Cys Ser Pro Gly Ser Ala Cys Gly Ser Gly 295 300 305 gag gta tcc cat gtg ttg ctg gcg ttg ggg ctt gag gag gat caa gca 1075 Glu Val Ser His Val Leu Leu Ala Leu Gly Leu Glu Glu Asp Gln Ala 310 315 320 325 cga acg gct gtg cgc tgt act ttt agt aca aca cac agc cgt gaa gat 1123 Arg Thr Ala Val Arg Cys Thr Phe Ser Thr Thr His Ser Arg Glu Asp 330 335 340 gcg ctc gtg gca gcc tct gct ctt aaa tcc gcg gtc gcc tta atc aga 1171 Ala Leu Val Ala Ala Ser Ala Leu Lys Ser Ala Val Ala Leu Ile Arg 345 350 355 ggg tgacgctagt cagaggttta cgg 1197 Gly <210> 648 <211> 358 <212> PRT <213> Corynebacterium glutamicum <400> 648 Met Leu Tyr Leu Asp Asn Ala Ala Thr Thr Ser Val Arg Asn Glu Ala 1 5 10 15 Leu Glu Ala Met Trp Pro Tyr Leu Thr Gly Ala Phe Gly Asn Pro Ser 20 25 30 Ser Pro His Glu Val Gly Arg Leu Ala Ser Ala Gly Leu Glu Asp Ala 35 40 45 Arg Thr Arg Val Ala Arg Ile Ile Gly Gly Arg Pro Thr Gln Val Thr 50 55 60 Phe Thr Ser Gly Gly Ser Glu Ala Asn Asn Leu Ala Ile Lys Gly Ala 65 70 75 80 Cys Leu Ala Asn Pro Arg Gly Arg His Leu Ile Thr Thr Pro Ile Glu 85 90 95 His Asp Ser Val Leu Glu Thr Ala Ala Tyr Leu Glu Arg Phe His Asp 100 105 110 Phe Glu Ile Thr Tyr Leu Ser Pro Asp His Thr Gly Leu Ile Ser Pro 115 120 125 Glu Gly Leu Arg Lys Ala Val Arg Pro Asp Thr Thr Leu Ile Ser Ile 130 135 140 Gly Tyr Ala Asn Asn Glu Val Gly Thr Ile Gln Pro Ile Ala Glu Leu 145 150 155 160 Ala Ala Val Ser Ser Thr Pro Phe His Thr Asp Ala Val Gln Ala Ala 165 170 175 His Leu Thr Phe Asp Leu Gly Val Asp Ala Leu Ser Leu Ser Gly His 180 185 190 Lys Phe Gly Ala Pro Lys Gly Ile Gly Val Leu Trp Ser Lys Leu Pro 195 200 205 Leu Glu Pro Val Ile His Gly Gly Gly Gln Glu Lys Gly Arg Arg Ser 210 215 220 Gly Thr Glu Asn Val Ala Gly Ala Ile Ala Phe Ala Thr Ala Leu Glu 225 230 235 240 Leu Ala Arg Ala Glu Ser Tyr Pro Asp Leu Gly Glu Phe Ile Glu Glu 245 250 255 Val Leu Thr Ile Pro Gly Ala His Leu Thr Gly His Pro Arg Met Arg 260 265 270 Ile Asp Gly His Ala Ser Phe Leu Phe Asp Ser Ile Gly Ser Glu Thr 275 280 285 Val Leu Leu Glu Leu Glu Arg Gln Gly Ile Val Cys Ser Pro Gly Ser 290 295 300 Ala Cys Gly Ser Gly Glu Val Ser His Val Leu Leu Ala Leu Gly Leu 305 310 315 320 Glu Glu Asp Gln Ala Arg Thr Ala Val Arg Cys Thr Phe Ser Thr Thr 325 330 335 His Ser Arg Glu Asp Ala Leu Val Ala Ala Ser Ala Leu Lys Ser Ala 340 345 350 Val Ala Leu Ile Arg Gly 355 <210> 649 <211> 920 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (79)..(897) <223> FRXA00262 <400> 649 cacacaggtg acgtttacgt cgggtggatc agaagccaac aacctcgctt atcaaaggag 60 cgtgcttagc taatccta gtg gcc ggg cac ctc atc acc acc ccg atc gag 111 Val Ala Gly His Leu Ile Thr Thr Pro Ile Glu 1 5 10 cat gac agt gtc cta gaa act gct gct tat ctt gaa agg ttt cat gat 159 His Asp Ser Val Leu Glu Thr Ala Ala Tyr Leu Glu Arg Phe His Asp 15 20 25 ttc gag atc acc tac cta tcc ccc gat cac act ggg ctg atc tcc ccg 207 Phe Glu Ile Thr Tyr Leu Ser Pro Asp His Thr Gly Leu Ile Ser Pro 30 35 40 gag ggt ctc cgc aaa gca gtc agg ccg gac acc aca ttg atc agc att 255 Glu Gly Leu Arg Lys Ala Val Arg Pro Asp Thr Thr Leu Ile Ser Ile 45 50 55 ggt tat gcc aac aat gag gtg gga acc att cag ccg ata gct gag ttg 303 Gly Tyr Ala Asn Asn Glu Val Gly Thr Ile Gln Pro Ile Ala Glu Leu 60 65 70 75 gcg gcg gta agc agt acg cct ttt cac acc gat gca gtg caa gct gca 351 Ala Ala Val Ser Ser Thr Pro Phe His Thr Asp Ala Val Gln Ala Ala 80 85 90 cat tta acc ttt gac ttg gga gtt gac gcg tta agt ttg tcg ggt cat 399 His Leu Thr Phe Asp Leu Gly Val Asp Ala Leu Ser Leu Ser Gly His 95 100 105 aaa ttc ggt gcg cct aaa ggg att gga gtg tta tgg tca aag ctt ccc 447 Lys Phe Gly Ala Pro Lys Gly Ile Gly Val Leu Trp Ser Lys Leu Pro 110 115 120 ctg gag ccg gta atc cat ggc ggc ggc cag gaa aaa ggg cgg cgt agt 495 Leu Glu Pro Val Ile His Gly Gly Gly Gln Glu Lys Gly Arg Arg Ser 125 130 135 ggc acg gaa aac gtt gcg ggg gct atc gcc ttt gcc act gcc ttg gaa 543 Gly Thr Glu Asn Val Ala Gly Ala Ile Ala Phe Ala Thr Ala Leu Glu 140 145 150 155 ttg gcc agg gcg gaa tcc tat cca gat ctt ggc gaa ttc atc gag gaa 591 Leu Ala Arg Ala Glu Ser Tyr Pro Asp Leu Gly Glu Phe Ile Glu Glu 160 165 170 gtt ctc act atc ccg gga gca cac ctg act gga cat cct agg atg cgc 639 Val Leu Thr Ile Pro Gly Ala His Leu Thr Gly His Pro Arg Met Arg 175 180 185 att gat gga cac gca tct ttt ctc ttc gac agc ata gga tct gaa act 687 Ile Asp Gly His Ala Ser Phe Leu Phe Asp Ser Ile Gly Ser Glu Thr 190 195 200 gtt ctt ctg gaa ttg gaa cgc caa ggc att gtg tgc tcc cct ggt tct 735 Val Leu Leu Glu Leu Glu Arg Gln Gly Ile Val Cys Ser Pro Gly Ser 205 210 215 gcc tgt ggt tcc gga gag gta tcc cat gtg ttg ctg gcg ttg ggg ctt 783 Ala Cys Gly Ser Gly Glu Val Ser His Val Leu Leu Ala Leu Gly Leu 220 225 230 235 gag gag gat caa gca cga acg gct gtg cgc tgt act ttt agt aca aca 831 Glu Glu Asp Gln Ala Arg Thr Ala Val Arg Cys Thr Phe Ser Thr Thr 240 245 250 cac agc cgt gaa gat gcg ctc gtg gca gcc tct gct ctt aaa tcc gcg 879 His Ser Arg Glu Asp Ala Leu Val Ala Ala Ser Ala Leu Lys Ser Ala 255 260 265 gtc gcc tta atc aga ggg tgacgctagt cagaggttta cgg 920 Val Ala Leu Ile Arg Gly 270 <210> 650 <211> 273 <212> PRT <213> Corynebacterium glutamicum <400> 650 Val Ala Gly His Leu Ile Thr Thr Pro Ile Glu His Asp Ser Val Leu 1 5 10 15 Glu Thr Ala Ala Tyr Leu Glu Arg Phe His Asp Phe Glu Ile Thr Tyr 20 25 30 Leu Ser Pro Asp His Thr Gly Leu Ile Ser Pro Glu Gly Leu Arg Lys 35 40 45 Ala Val Arg Pro Asp Thr Thr Leu Ile Ser Ile Gly Tyr Ala Asn Asn 50 55 60 Glu Val Gly Thr Ile Gln Pro Ile Ala Glu Leu Ala Ala Val Ser Ser 65 70 75 80 Thr Pro Phe His Thr Asp Ala Val Gln Ala Ala His Leu Thr Phe Asp 85 90 95 Leu Gly Val Asp Ala Leu Ser Leu Ser Gly His Lys Phe Gly Ala Pro 100 105 110 Lys Gly Ile Gly Val Leu Trp Ser Lys Leu Pro Leu Glu Pro Val Ile 115 120 125 His Gly Gly Gly Gln Glu Lys Gly Arg Arg Ser Gly Thr Glu Asn Val 130 135 140 Ala Gly Ala Ile Ala Phe Ala Thr Ala Leu Glu Leu Ala Arg Ala Glu 145 150 155 160 Ser Tyr Pro Asp Leu Gly Glu Phe Ile Glu Glu Val Leu Thr Ile Pro 165 170 175 Gly Ala His Leu Thr Gly His Pro Arg Met Arg Ile Asp Gly His Ala 180 185 190 Ser Phe Leu Phe Asp Ser Ile Gly Ser Glu Thr Val Leu Leu Glu Leu 195 200 205 Glu Arg Gln Gly Ile Val Cys Ser Pro Gly Ser Ala Cys Gly Ser Gly 210 215 220 Glu Val Ser His Val Leu Leu Ala Leu Gly Leu Glu Glu Asp Gln Ala 225 230 235 240 Arg Thr Ala Val Arg Cys Thr Phe Ser Thr Thr His Ser Arg Glu Asp 245 250 255 Ala Leu Val Ala Ala Ser Ala Leu Lys Ser Ala Val Ala Leu Ile Arg 260 265 270 Gly <210> 651 <211> 1296 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1273) <223> RXN00435 <400> 651 cgacaggtga attcatgcac gtttgagtgt cccgtgtgtg gggtaatgtt gtccaagaga 60 gtggaaggaa atgctgtggc ggttgaaagg agtgcctttc gtg ggt ttt gat gtg 115 Val Gly Phe Asp Val 1 5 gcc agg gtt cgg ggg ctt tat acc tct ttg ggc gat ggc tgg acg tac 163 Ala Arg Val Arg Gly Leu Tyr Thr Ser Leu Gly Asp Gly Trp Thr Tyr 10 15 20 ctt aat tca cat caa att ccg cag gtt ccg gag cgg gtg gcg tcg gga 211 Leu Asn Ser His Gln Ile Pro Gln Val Pro Glu Arg Val Ala Ser Gly 25 30 35 gtt gcg gcg gct ttc cgc acg cat gcg cag att tct gag gtg acg tcg 259 Val Ala Ala Ala Phe Arg Thr His Ala Gln Ile Ser Glu Val Thr Ser 40 45 50 cag ccg att gcg gtg gat cag ttg gag gct gct cgc gag gca gtt gcg 307 Gln Pro Ile Ala Val Asp Gln Leu Glu Ala Ala Arg Glu Ala Val Ala 55 60 65 tcg ttg gcg ggt gtg gat ccg gac tgt gtt gtg ctg ggt ccc acg agg 355 Ser Leu Ala Gly Val Asp Pro Asp Cys Val Val Leu Gly Pro Thr Arg 70 75 80 85 cag ttt ttg gct cat aca ttg gcg cgc ggt ttg ggt ggg ttt gta cgt 403 Gln Phe Leu Ala His Thr Leu Ala Arg Gly Leu Gly Gly Phe Val Arg 90 95 100 cga aaa gcg ggc gtg gtg ttg tcg cgc gcg gac gcg gac tgg ctg acc 451 Arg Lys Ala Gly Val Val Leu Ser Arg Ala Asp Ala Asp Trp Leu Thr 105 110 115 gcg ccg ttc cgc tcc ctc gac ggc gtt ttt agc tgg gcc gag ccc gat 499 Ala Pro Phe Arg Ser Leu Asp Gly Val Phe Ser Trp Ala Glu Pro Asp 120 125 130 ttg ggc acc ggc atg ctg ccg gat tgg cag tac gag aag ctt gtt gac 547 Leu Gly Thr Gly Met Leu Pro Asp Trp Gln Tyr Glu Lys Leu Val Asp 135 140 145 ggc tcg acg cgc ctt gtc gtg ctc agc gcc gcg cac ccg ctg ctc ggc 595 Gly Ser Thr Arg Leu Val Val Leu Ser Ala Ala His Pro Leu Leu Gly 150 155 160 165 acg gtc gcc cca gtg ggc aag att gtg gat aaa gtg cgg gcg cgt tcg 643 Thr Val Ala Pro Val Gly Lys Ile Val Asp Lys Val Arg Ala Arg Ser 170 175 180 cgt gcc tgg gtg ctt gtc gac gcc acc acc tac gca gcc tac cgc ccc 691 Arg Ala Trp Val Leu Val Asp Ala Thr Thr Tyr Ala Ala Tyr Arg Pro 185 190 195 ctg cgc cta gac gag tgg gaa gcc gat atc gtc atg ctt gat ctc ggc 739 Leu Arg Leu Asp Glu Trp Glu Ala Asp Ile Val Met Leu Asp Leu Gly 200 205 210 gag ttg ggc ggc ccg cag att tcg gcg ttg att ttc cgt gat acc tcg 787 Glu Leu Gly Gly Pro Gln Ile Ser Ala Leu Ile Phe Arg Asp Thr Ser 215 220 225 atg ttc ccg cgc ctg gat cgc acc gtt cca ctc gaa ctg ccc gca agc 835 Met Phe Pro Arg Leu Asp Arg Thr Val Pro Leu Glu Leu Pro Ala Ser 230 235 240 245 tcc ctg ccg cat ggg ctg ctc ggc ggc gtg ccc aac ctg gtg cgg cac 883 Ser Leu Pro His Gly Leu Leu Gly Gly Val Pro Asn Leu Val Arg His 250 255 260 ctg gga aac ctg gat gaa aac gcc ccg tcc gtc gtt gag gcg atg ggg 931 Leu Gly Asn Leu Asp Glu Asn Ala Pro Ser Val Val Glu Ala Met Gly 265 270 275 gag atg gcg aaa ttc cac aag gga ctt ttt gag cat ctt gtg gaa tcg 979 Glu Met Ala Lys Phe His Lys Gly Leu Phe Glu His Leu Val Glu Ser 280 285 290 ctc gaa gga ctt cac gcg gtg cat atc gtg gga att tcc ggc gat gcc 1027 Leu Glu Gly Leu His Ala Val His Ile Val Gly Ile Ser Gly Asp Ala 295 300 305 gca ggt caa gac gcc ccg ttc ctg gat cga gtg ccc cgc ttg acc ttc 1075 Ala Gly Gln Asp Ala Pro Phe Leu Asp Arg Val Pro Arg Leu Thr Phe 310 315 320 325 acc atg gaa ggc gtg ccc gca gat atg gtg tac cgc cga ttg gtg gac 1123 Thr Met Glu Gly Val Pro Ala Asp Met Val Tyr Arg Arg Leu Val Asp 330 335 340 aat cgt ttg atc act acc gtc agc cct gct gac ccg ctg ctc gaa gca 1171 Asn Arg Leu Ile Thr Thr Val Ser Pro Ala Asp Pro Leu Leu Glu Ala 345 350 355 atg ggt gtg act gaa gct ggc gga tcg atc act atc gga cta agc ccg 1219 Met Gly Val Thr Glu Ala Gly Gly Ser Ile Thr Ile Gly Leu Ser Pro 360 365 370 ttt agc acc tac tat gaa gtg gat cag ctg acc agg gtg ctg gca tcg 1267 Phe Ser Thr Tyr Tyr Glu Val Asp Gln Leu Thr Arg Val Leu Ala Ser 375 380 385 ctt gcc taaaccgcaa gcacgagctt gcc 1296 Leu Ala 390 <210> 652 <211> 391 <212> PRT <213> Corynebacterium glutamicum <400> 652 Val Gly Phe Asp Val Ala Arg Val Arg Gly Leu Tyr Thr Ser Leu Gly 1 5 10 15 Asp Gly Trp Thr Tyr Leu Asn Ser His Gln Ile Pro Gln Val Pro Glu 20 25 30 Arg Val Ala Ser Gly Val Ala Ala Ala Phe Arg Thr His Ala Gln Ile 35 40 45 Ser Glu Val Thr Ser Gln Pro Ile Ala Val Asp Gln Leu Glu Ala Ala 50 55 60 Arg Glu Ala Val Ala Ser Leu Ala Gly Val Asp Pro Asp Cys Val Val 65 70 75 80 Leu Gly Pro Thr Arg Gln Phe Leu Ala His Thr Leu Ala Arg Gly Leu 85 90 95 Gly Gly Phe Val Arg Arg Lys Ala Gly Val Val Leu Ser Arg Ala Asp 100 105 110 Ala Asp Trp Leu Thr Ala Pro Phe Arg Ser Leu Asp Gly Val Phe Ser 115 120 125 Trp Ala Glu Pro Asp Leu Gly Thr Gly Met Leu Pro Asp Trp Gln Tyr 130 135 140 Glu Lys Leu Val Asp Gly Ser Thr Arg Leu Val Val Leu Ser Ala Ala 145 150 155 160 His Pro Leu Leu Gly Thr Val Ala Pro Val Gly Lys Ile Val Asp Lys 165 170 175 Val Arg Ala Arg Ser Arg Ala Trp Val Leu Val Asp Ala Thr Thr Tyr 180 185 190 Ala Ala Tyr Arg Pro Leu Arg Leu Asp Glu Trp Glu Ala Asp Ile Val 195 200 205 Met Leu Asp Leu Gly Glu Leu Gly Gly Pro Gln Ile Ser Ala Leu Ile 210 215 220 Phe Arg Asp Thr Ser Met Phe Pro Arg Leu Asp Arg Thr Val Pro Leu 225 230 235 240 Glu Leu Pro Ala Ser Ser Leu Pro His Gly Leu Leu Gly Gly Val Pro 245 250 255 Asn Leu Val Arg His Leu Gly Asn Leu Asp Glu Asn Ala Pro Ser Val 260 265 270 Val Glu Ala Met Gly Glu Met Ala Lys Phe His Lys Gly Leu Phe Glu 275 280 285 His Leu Val Glu Ser Leu Glu Gly Leu His Ala Val His Ile Val Gly 290 295 300 Ile Ser Gly Asp Ala Ala Gly Gln Asp Ala Pro Phe Leu Asp Arg Val 305 310 315 320 Pro Arg Leu Thr Phe Thr Met Glu Gly Val Pro Ala Asp Met Val Tyr 325 330 335 Arg Arg Leu Val Asp Asn Arg Leu Ile Thr Thr Val Ser Pro Ala Asp 340 345 350 Pro Leu Leu Glu Ala Met Gly Val Thr Glu Ala Gly Gly Ser Ile Thr 355 360 365 Ile Gly Leu Ser Pro Phe Ser Thr Tyr Tyr Glu Val Asp Gln Leu Thr 370 375 380 Arg Val Leu Ala Ser Leu Ala 385 390 <210> 653 <211> 638 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(615) <223> FRXA00435 <400> 653 gtc gac gcc acc acc tac gca gcc tac cgc ccc ctg cgc cta gac gag 48 Val Asp Ala Thr Thr Tyr Ala Ala Tyr Arg Pro Leu Arg Leu Asp Glu 1 5 10 15 tgg gaa gcc gat atc gtc atg ctt gat ctc ggc gag ttg ggc ggc ccg 96 Trp Glu Ala Asp Ile Val Met Leu Asp Leu Gly Glu Leu Gly Gly Pro 20 25 30 cag att tcg gcg ttg att ttc cgt gat acc tcg atg ttc ccg cgc ctg 144 Gln Ile Ser Ala Leu Ile Phe Arg Asp Thr Ser Met Phe Pro Arg Leu 35 40 45 gat cgc acc gtt cca ctc gaa ctg ccc gca agc tcc ctg ccg cat ggg 192 Asp Arg Thr Val Pro Leu Glu Leu Pro Ala Ser Ser Leu Pro His Gly 50 55 60 ctg ctc ggc ggc gtg ccc aac ctg gtg cgg cac ctg gga aac ctg gat 240 Leu Leu Gly Gly Val Pro Asn Leu Val Arg His Leu Gly Asn Leu Asp 65 70 75 80 gaa aac gcc ccg tcc gtc gtt gag gcg atg ggg gag atg gcg aaa ttc 288 Glu Asn Ala Pro Ser Val Val Glu Ala Met Gly Glu Met Ala Lys Phe 85 90 95 cac aag gga ctt ttt gag cat ctt gtg gaa tcg ctc gaa gga ctt cac 336 His Lys Gly Leu Phe Glu His Leu Val Glu Ser Leu Glu Gly Leu His 100 105 110 gcg gtg cat atc gtg gga att tcc ggc gat gcc gca ggt caa gac gcc 384 Ala Val His Ile Val Gly Ile Ser Gly Asp Ala Ala Gly Gln Asp Ala 115 120 125 ccg ttc ctg gat cga gtg ccc cgc ttg acc ttc acc atg gaa ggc gtg 432 Pro Phe Leu Asp Arg Val Pro Arg Leu Thr Phe Thr Met Glu Gly Val 130 135 140 ccc gca gat atg gtg tac cgc cga ttg gtg gac aat cgt ttg atc act 480 Pro Ala Asp Met Val Tyr Arg Arg Leu Val Asp Asn Arg Leu Ile Thr 145 150 155 160 acc gtc agc cct gct gac ccg ctg ctc gaa gca atg ggt gtg act gaa 528 Thr Val Ser Pro Ala Asp Pro Leu Leu Glu Ala Met Gly Val Thr Glu 165 170 175 gct ggc gga tcg atc act atc gga cta agc ccg ttt agc acc tac tat 576 Ala Gly Gly Ser Ile Thr Ile Gly Leu Ser Pro Phe Ser Thr Tyr Tyr 180 185 190 gaa gtg gat cag ctg acc agg gtg ctg gca tcg ctt gcc taaaccgcaa 625 Glu Val Asp Gln Leu Thr Arg Val Leu Ala Ser Leu Ala 195 200 205 gcacgagctt gcc 638 <210> 654 <211> 205 <212> PRT <213> Corynebacterium glutamicum <400> 654 Val Asp Ala Thr Thr Tyr Ala Ala Tyr Arg Pro Leu Arg Leu Asp Glu 1 5 10 15 Trp Glu Ala Asp Ile Val Met Leu Asp Leu Gly Glu Leu Gly Gly Pro 20 25 30 Gln Ile Ser Ala Leu Ile Phe Arg Asp Thr Ser Met Phe Pro Arg Leu 35 40 45 Asp Arg Thr Val Pro Leu Glu Leu Pro Ala Ser Ser Leu Pro His Gly 50 55 60 Leu Leu Gly Gly Val Pro Asn Leu Val Arg His Leu Gly Asn Leu Asp 65 70 75 80 Glu Asn Ala Pro Ser Val Val Glu Ala Met Gly Glu Met Ala Lys Phe 85 90 95 His Lys Gly Leu Phe Glu His Leu Val Glu Ser Leu Glu Gly Leu His 100 105 110 Ala Val His Ile Val Gly Ile Ser Gly Asp Ala Ala Gly Gln Asp Ala 115 120 125 Pro Phe Leu Asp Arg Val Pro Arg Leu Thr Phe Thr Met Glu Gly Val 130 135 140 Pro Ala Asp Met Val Tyr Arg Arg Leu Val Asp Asn Arg Leu Ile Thr 145 150 155 160 Thr Val Ser Pro Ala Asp Pro Leu Leu Glu Ala Met Gly Val Thr Glu 165 170 175 Ala Gly Gly Ser Ile Thr Ile Gly Leu Ser Pro Phe Ser Thr Tyr Tyr 180 185 190 Glu Val Asp Gln Leu Thr Arg Val Leu Ala Ser Leu Ala 195 200 205 <210> 655 <211> 535 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(535) <223> FRXA02801 <400> 655 cgacaggtga attcatgcac gtttgagtgt cccgtgtgtg gggtaatgtt gtccaagaga 60 gtggaaggaa atgctgtggc ggttgaaagg agtgcctttc gtg ggt ttt gat gtg 115 Val Gly Phe Asp Val 1 5 gcc agg gtt cgg ggg ctt tat acc tct ttg ggc gat ggc tgg acg tac 163 Ala Arg Val Arg Gly Leu Tyr Thr Ser Leu Gly Asp Gly Trp Thr Tyr 10 15 20 ctt aat tca cat caa att ccg cag gtt ccg gag cgg gtg gcg tcg gga 211 Leu Asn Ser His Gln Ile Pro Gln Val Pro Glu Arg Val Ala Ser Gly 25 30 35 gtt gcg gcg gct ttc cgc acg cat gcg cag att tct gag gtg acg tcg 259 Val Ala Ala Ala Phe Arg Thr His Ala Gln Ile Ser Glu Val Thr Ser 40 45 50 cag ccg att gcg gtg gat cag ttg gag gct gct cgc gag gca gtt gcg 307 Gln Pro Ile Ala Val Asp Gln Leu Glu Ala Ala Arg Glu Ala Val Ala 55 60 65 tcg ttg gcg ggt gtg gat ccg gac tgt gtt gtg ctg ggt ccc acg agg 355 Ser Leu Ala Gly Val Asp Pro Asp Cys Val Val Leu Gly Pro Thr Arg 70 75 80 85 cag ttt ttg gct cat aca ttg gcg cgc ggt ttg ggt ggg ttt gta cgt 403 Gln Phe Leu Ala His Thr Leu Ala Arg Gly Leu Gly Gly Phe Val Arg 90 95 100 cga aaa gcg ggc gtg gtg ttg tcg cgc gcg gac gcg gac tgg ctg acc 451 Arg Lys Ala Gly Val Val Leu Ser Arg Ala Asp Ala Asp Trp Leu Thr 105 110 115 gcg ccg ttc cgc tcc ctc gac ggc gtt ttt agc tgg gcc gag ccc gat 499 Ala Pro Phe Arg Ser Leu Asp Gly Val Phe Ser Trp Ala Glu Pro Asp 120 125 130 ttg ggc acc ggc atg ctg ccg gat tgg cag tac cag 535 Leu Gly Thr Gly Met Leu Pro Asp Trp Gln Tyr Gln 135 140 145 <210> 656 <211> 145 <212> PRT <213> Corynebacterium glutamicum <400> 656 Val Gly Phe Asp Val Ala Arg Val Arg Gly Leu Tyr Thr Ser Leu Gly 1 5 10 15 Asp Gly Trp Thr Tyr Leu Asn Ser His Gln Ile Pro Gln Val Pro Glu 20 25 30 Arg Val Ala Ser Gly Val Ala Ala Ala Phe Arg Thr His Ala Gln Ile 35 40 45 Ser Glu Val Thr Ser Gln Pro Ile Ala Val Asp Gln Leu Glu Ala Ala 50 55 60 Arg Glu Ala Val Ala Ser Leu Ala Gly Val Asp Pro Asp Cys Val Val 65 70 75 80 Leu Gly Pro Thr Arg Gln Phe Leu Ala His Thr Leu Ala Arg Gly Leu 85 90 95 Gly Gly Phe Val Arg Arg Lys Ala Gly Val Val Leu Ser Arg Ala Asp 100 105 110 Ala Asp Trp Leu Thr Ala Pro Phe Arg Ser Leu Asp Gly Val Phe Ser 115 120 125 Trp Ala Glu Pro Asp Leu Gly Thr Gly Met Leu Pro Asp Trp Gln Tyr 130 135 140 Gln 145 <210> 657 <211> 1386 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1363) <223> RXA02516 <400> 657 ttcattcacg ttttcgcgaa tggccagatt gtgaccaccg gtggcgctga gcttgctgac 60 aagctcgagg ctgacggcta cgaccagttc atcaagtaac atg tcc gat ttc ctc 115 Met Ser Asp Phe Leu 1 5 aat gca gat gga tcc ctc aat gtg gat aag gtg cgg gaa gaa ttc cca 163 Asn Ala Asp Gly Ser Leu Asn Val Asp Lys Val Arg Glu Glu Phe Pro 10 15 20 atc ctg aag cgc act gtt agg gat ggg aaa ccg ctt gct tac ctg gac 211 Ile Leu Lys Arg Thr Val Arg Asp Gly Lys Pro Leu Ala Tyr Leu Asp 25 30 35 tca ggt gcg aca tcg cag cga ccc gag cgg gtg tgg cgt gca gag gag 259 Ser Gly Ala Thr Ser Gln Arg Pro Glu Arg Val Trp Arg Ala Glu Glu 40 45 50 cac ttt gtg ctg cac acc aac gcc ccc gtg cac cgc ggt gcc tac caa 307 His Phe Val Leu His Thr Asn Ala Pro Val His Arg Gly Ala Tyr Gln 55 60 65 ctg gct gag gaa gca acg gat gct tat gaa ggt gcc cgc gag aag atc 355 Leu Ala Glu Glu Ala Thr Asp Ala Tyr Glu Gly Ala Arg Glu Lys Ile 70 75 80 85 gct gcc ttt gtt ggt gcc gag cag cat gaa att gcg ttc act aag aat 403 Ala Ala Phe Val Gly Ala Glu Gln His Glu Ile Ala Phe Thr Lys Asn 90 95 100 gca act gaa gca ctc aat ctt gtt gcg tac acc ttg ggt gat gac cgt 451 Ala Thr Glu Ala Leu Asn Leu Val Ala Tyr Thr Leu Gly Asp Asp Arg 105 110 115 tcc ggt aag tat cgt gtc cag gcc ggg gat acc gtg gtc atc acg gag 499 Ser Gly Lys Tyr Arg Val Gln Ala Gly Asp Thr Val Val Ile Thr Glu 120 125 130 cta gag cac cac gca aac ttg gtg cca tgg cag gag ctg tgc cgt cga 547 Leu Glu His His Ala Asn Leu Val Pro Trp Gln Glu Leu Cys Arg Arg 135 140 145 acc ggt gcg aca ttg aag tgg tac aag gtg act gaa gat ggt cgc att 595 Thr Gly Ala Thr Leu Lys Trp Tyr Lys Val Thr Glu Asp Gly Arg Ile 150 155 160 165 gat ctc gat tca ctc gag ctt gat gaa act gtc aag gtc gtt gcc ttc 643 Asp Leu Asp Ser Leu Glu Leu Asp Glu Thr Val Lys Val Val Ala Phe 170 175 180 act cac cag tcc aat gtg acc ggt gct gtg gct gat gtt cca gag ttg 691 Thr His Gln Ser Asn Val Thr Gly Ala Val Ala Asp Val Pro Glu Leu 185 190 195 gtt cgt cgt gcc aag gct gtc ggc gct ctc acg gtg ctt gat gcg tgc 739 Val Arg Arg Ala Lys Ala Val Gly Ala Leu Thr Val Leu Asp Ala Cys 200 205 210 cag tct gtt cct cat atg cca gtg aat ttc cac gag ctg gat gta gat 787 Gln Ser Val Pro His Met Pro Val Asn Phe His Glu Leu Asp Val Asp 215 220 225 ttc tct gca ttc tct ggc cat aag atg ctg gga cct gca ggc gtg ggc 835 Phe Ser Ala Phe Ser Gly His Lys Met Leu Gly Pro Ala Gly Val Gly 230 235 240 245 gtt gtg tat gca aag tcc cca atc ttg gat gaa ctg cca cca ttt ttg 883 Val Val Tyr Ala Lys Ser Pro Ile Leu Asp Glu Leu Pro Pro Phe Leu 250 255 260 act ggt ggt tcc atg att gaa gtt gtc acc atg gag ggt tcc acc tac 931 Thr Gly Gly Ser Met Ile Glu Val Val Thr Met Glu Gly Ser Thr Tyr 265 270 275 gct gcc gca cct caa cgt ttt gag gcc ggc acg cag atg acc agc cag 979 Ala Ala Ala Pro Gln Arg Phe Glu Ala Gly Thr Gln Met Thr Ser Gln 280 285 290 gtt gtg ggc ttg ggt gct gcc gtg gac atg ctg aat gaa atc ggt atg 1027 Val Val Gly Leu Gly Ala Ala Val Asp Met Leu Asn Glu Ile Gly Met 295 300 305 gaa gca atc gca gcg cat gag cac gca ttg act gct tac gcg ttg gaa 1075 Glu Ala Ile Ala Ala His Glu His Ala Leu Thr Ala Tyr Ala Leu Glu 310 315 320 325 aag ctc acg gca att aag gga cta acc att gct ggt cct ttg act gca 1123 Lys Leu Thr Ala Ile Lys Gly Leu Thr Ile Ala Gly Pro Leu Thr Ala 330 335 340 gag cag cgc ggc ggt gca atc agc ttc ggt gtc gag ggc att cac cca 1171 Glu Gln Arg Gly Gly Ala Ile Ser Phe Gly Val Glu Gly Ile His Pro 345 350 355 cac gat cta ggc caa gtg ctt gac gat cag ggc gtg aat atc cgc gtc 1219 His Asp Leu Gly Gln Val Leu Asp Asp Gln Gly Val Asn Ile Arg Val 360 365 370 ggc cac cac tgc gcg tgg ccc gtg cac cgc agc atg aac gta caa tcg 1267 Gly His His Cys Ala Trp Pro Val His Arg Ser Met Asn Val Gln Ser 375 380 385 aca gca aga gca tct ttc tat ctc tat aac acc ttc gaa gaa atc gac 1315 Thr Ala Arg Ala Ser Phe Tyr Leu Tyr Asn Thr Phe Glu Glu Ile Asp 390 395 400 405 cgc ctc gcg gca gcg atc gag aag gcc aag caa ttc ttt gga gtt gag 1363 Arg Leu Ala Ala Ala Ile Glu Lys Ala Lys Gln Phe Phe Gly Val Glu 410 415 420 taatgaacct tgagcagatg tac 1386 <210> 658 <211> 421 <212> PRT <213> Corynebacterium glutamicum <400> 658 Met Ser Asp Phe Leu Asn Ala Asp Gly Ser Leu Asn Val Asp Lys Val 1 5 10 15 Arg Glu Glu Phe Pro Ile Leu Lys Arg Thr Val Arg Asp Gly Lys Pro 20 25 30 Leu Ala Tyr Leu Asp Ser Gly Ala Thr Ser Gln Arg Pro Glu Arg Val 35 40 45 Trp Arg Ala Glu Glu His Phe Val Leu His Thr Asn Ala Pro Val His 50 55 60 Arg Gly Ala Tyr Gln Leu Ala Glu Glu Ala Thr Asp Ala Tyr Glu Gly 65 70 75 80 Ala Arg Glu Lys Ile Ala Ala Phe Val Gly Ala Glu Gln His Glu Ile 85 90 95 Ala Phe Thr Lys Asn Ala Thr Glu Ala Leu Asn Leu Val Ala Tyr Thr 100 105 110 Leu Gly Asp Asp Arg Ser Gly Lys Tyr Arg Val Gln Ala Gly Asp Thr 115 120 125 Val Val Ile Thr Glu Leu Glu His His Ala Asn Leu Val Pro Trp Gln 130 135 140 Glu Leu Cys Arg Arg Thr Gly Ala Thr Leu Lys Trp Tyr Lys Val Thr 145 150 155 160 Glu Asp Gly Arg Ile Asp Leu Asp Ser Leu Glu Leu Asp Glu Thr Val 165 170 175 Lys Val Val Ala Phe Thr His Gln Ser Asn Val Thr Gly Ala Val Ala 180 185 190 Asp Val Pro Glu Leu Val Arg Arg Ala Lys Ala Val Gly Ala Leu Thr 195 200 205 Val Leu Asp Ala Cys Gln Ser Val Pro His Met Pro Val Asn Phe His 210 215 220 Glu Leu Asp Val Asp Phe Ser Ala Phe Ser Gly His Lys Met Leu Gly 225 230 235 240 Pro Ala Gly Val Gly Val Val Tyr Ala Lys Ser Pro Ile Leu Asp Glu 245 250 255 Leu Pro Pro Phe Leu Thr Gly Gly Ser Met Ile Glu Val Val Thr Met 260 265 270 Glu Gly Ser Thr Tyr Ala Ala Ala Pro Gln Arg Phe Glu Ala Gly Thr 275 280 285 Gln Met Thr Ser Gln Val Val Gly Leu Gly Ala Ala Val Asp Met Leu 290 295 300 Asn Glu Ile Gly Met Glu Ala Ile Ala Ala His Glu His Ala Leu Thr 305 310 315 320 Ala Tyr Ala Leu Glu Lys Leu Thr Ala Ile Lys Gly Leu Thr Ile Ala 325 330 335 Gly Pro Leu Thr Ala Glu Gln Arg Gly Gly Ala Ile Ser Phe Gly Val 340 345 350 Glu Gly Ile His Pro His Asp Leu Gly Gln Val Leu Asp Asp Gln Gly 355 360 365 Val Asn Ile Arg Val Gly His His Cys Ala Trp Pro Val His Arg Ser 370 375 380 Met Asn Val Gln Ser Thr Ala Arg Ala Ser Phe Tyr Leu Tyr Asn Thr 385 390 395 400 Phe Glu Glu Ile Asp Arg Leu Ala Ala Ala Ile Glu Lys Ala Lys Gln 405 410 415 Phe Phe Gly Val Glu 420 <210> 659 <211> 570 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(547) <223> RXA02517 <400> 659 cgacagcaag agcatctttc tatctctata acaccttcga agaaatcgac cgcctcgcgg 60 cagcgatcga gaaggccaag caattctttg gagttgagta atg aac ctt gag cag 115 Met Asn Leu Glu Gln 1 5 atg tac cag gag gtg atc ctg gac cac tac aaa aac cca cag cac aag 163 Met Tyr Gln Glu Val Ile Leu Asp His Tyr Lys Asn Pro Gln His Lys 10 15 20 ggc ctt cgg gat cct ttc gat gct gag gtt cac cac gtc aac cct tct 211 Gly Leu Arg Asp Pro Phe Asp Ala Glu Val His His Val Asn Pro Ser 25 30 35 tgt ggc gac gaa ttg act ctg cgc gtg aag ctg tct gag gac ggc tcc 259 Cys Gly Asp Glu Leu Thr Leu Arg Val Lys Leu Ser Glu Asp Gly Ser 40 45 50 acc gtg gag gac gtc tcc tac gaa gca gtt ggt tgc tca atc agc cag 307 Thr Val Glu Asp Val Ser Tyr Glu Ala Val Gly Cys Ser Ile Ser Gln 55 60 65 gcc tcc acg tcc gtt atg gcc gag gag atc gtg ggc caa ccc gtc gac 355 Ala Ser Thr Ser Val Met Ala Glu Glu Ile Val Gly Gln Pro Val Asp 70 75 80 85 aag gcg ctg gaa aag ctc aca gaa ttt gag aag atg atc gtt tcc cgc 403 Lys Ala Leu Glu Lys Leu Thr Glu Phe Glu Lys Met Ile Val Ser Arg 90 95 100 ggt cag ttt gtt ggc gat gaa gat ctc atc gga gat ggc gtt gct ttc 451 Gly Gln Phe Val Gly Asp Glu Asp Leu Ile Gly Asp Gly Val Ala Phe 105 110 115 tcc gga gtc gcc aag tac ccg gca cgc gtg aag tgc gcg ctg ctt ggg 499 Ser Gly Val Ala Lys Tyr Pro Ala Arg Val Lys Cys Ala Leu Leu Gly 120 125 130 tgg aag gct ttc cag gcg gca acc gct gac gct gtt gcg cac gca cat 547 Trp Lys Ala Phe Gln Ala Ala Thr Ala Asp Ala Val Ala His Ala His 135 140 145 tagcccgctg tattaattgg agg 570 <210> 660 <211> 149 <212> PRT <213> Corynebacterium glutamicum <400> 660 Met Asn Leu Glu Gln Met Tyr Gln Glu Val Ile Leu Asp His Tyr Lys 1 5 10 15 Asn Pro Gln His Lys Gly Leu Arg Asp Pro Phe Asp Ala Glu Val His 20 25 30 His Val Asn Pro Ser Cys Gly Asp Glu Leu Thr Leu Arg Val Lys Leu 35 40 45 Ser Glu Asp Gly Ser Thr Val Glu Asp Val Ser Tyr Glu Ala Val Gly 50 55 60 Cys Ser Ile Ser Gln Ala Ser Thr Ser Val Met Ala Glu Glu Ile Val 65 70 75 80 Gly Gln Pro Val Asp Lys Ala Leu Glu Lys Leu Thr Glu Phe Glu Lys 85 90 95 Met Ile Val Ser Arg Gly Gln Phe Val Gly Asp Glu Asp Leu Ile Gly 100 105 110 Asp Gly Val Ala Phe Ser Gly Val Ala Lys Tyr Pro Ala Arg Val Lys 115 120 125 Cys Ala Leu Leu Gly Trp Lys Ala Phe Gln Ala Ala Thr Ala Asp Ala 130 135 140 Val Ala His Ala His 145 <210> 661 <211> 1167 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1144) <223> RXA01747 <400> 661 cgaagtagag ccgattgcag aatcggcgga atgagacgtc gaaaagcgtt taagctttcc 60 ctaaaaatat cactaactcg aaagatgtaa ggttgcattt gtg act atc gca cct 115 Val Thr Ile Ala Pro 1 5 gaa gga cga cga ctg cta cgc gtc gaa gct cga aac tca gaa acc ccg 163 Glu Gly Arg Arg Leu Leu Arg Val Glu Ala Arg Asn Ser Glu Thr Pro 10 15 20 att gag acg aag cct cga tgg att aga aac cag gtc aaa aac gga cct 211 Ile Glu Thr Lys Pro Arg Trp Ile Arg Asn Gln Val Lys Asn Gly Pro 25 30 35 gag tat cag gat atg aag gaa cgt gtc gct ggc gca tca cta cac act 259 Glu Tyr Gln Asp Met Lys Glu Arg Val Ala Gly Ala Ser Leu His Thr 40 45 50 gtg tgt cag gag gct ggc tgt cct aat atc cat gag tgt tgg gaa tcc 307 Val Cys Gln Glu Ala Gly Cys Pro Asn Ile His Glu Cys Trp Glu Ser 55 60 65 cgt gag gca acc ttc ctc att ggt ggc gcc aac tgc tct cgc cgc tgt 355 Arg Glu Ala Thr Phe Leu Ile Gly Gly Ala Asn Cys Ser Arg Arg Cys 70 75 80 85 gat ttc tgc atg atc aac tcg gct cgc cct gag cca ctc gac cgc ggt 403 Asp Phe Cys Met Ile Asn Ser Ala Arg Pro Glu Pro Leu Asp Arg Gly 90 95 100 gag cca ctg cgt gtc gct gag tct gtt cgt gag atg cag ctg aat tac 451 Glu Pro Leu Arg Val Ala Glu Ser Val Arg Glu Met Gln Leu Asn Tyr 105 110 115 tcc acc atc acc ggt gtt acc cgt gat gat ctg gat gat gaa ggc gca 499 Ser Thr Ile Thr Gly Val Thr Arg Asp Asp Leu Asp Asp Glu Gly Ala 120 125 130 tgg ctg tac tca gaa gtg gtt cgt aag atc cac gag ctg aac cca cac 547 Trp Leu Tyr Ser Glu Val Val Arg Lys Ile His Glu Leu Asn Pro His 135 140 145 acc ggt gtg gaa aac ctg gtg cct gat ttc tcc ggc aag aag gat ctg 595 Thr Gly Val Glu Asn Leu Val Pro Asp Phe Ser Gly Lys Lys Asp Leu 150 155 160 165 ctg cag gaa gtt ttt gaa tcc cgc cca gag gtt ttc gct cac aac gtg 643 Leu Gln Glu Val Phe Glu Ser Arg Pro Glu Val Phe Ala His Asn Val 170 175 180 gaa act gtg cca cgt att ttc aag cgc att cgc cca gca ttc cgc tac 691 Glu Thr Val Pro Arg Ile Phe Lys Arg Ile Arg Pro Ala Phe Arg Tyr 185 190 195 gag cgt tca ctt gat gtg atc cgt cag gct cgc gat ttc ggt ctg gtg 739 Glu Arg Ser Leu Asp Val Ile Arg Gln Ala Arg Asp Phe Gly Leu Val 200 205 210 acc aag tcc aac ctg att ttg ggc atg ggt gaa acc aag gaa gaa atc 787 Thr Lys Ser Asn Leu Ile Leu Gly Met Gly Glu Thr Lys Glu Glu Ile 215 220 225 acc gag gcg ctg cag gat ctg cac gac gct ggc tgt gac atc atc acc 835 Thr Glu Ala Leu Gln Asp Leu His Asp Ala Gly Cys Asp Ile Ile Thr 230 235 240 245 atc acc cag tac ctg cgt cct ggt cct ttg ttc cac ccc atc gag cgt 883 Ile Thr Gln Tyr Leu Arg Pro Gly Pro Leu Phe His Pro Ile Glu Arg 250 255 260 tgg gtg aag cct gag gag ttc ctc gag cac gct gat gct gca aag gaa 931 Trp Val Lys Pro Glu Glu Phe Leu Glu His Ala Asp Ala Ala Lys Glu 265 270 275 atg ggc ttc gct gct gtt atg tcc ggc cca ttg gtt cgt tcc tct tac 979 Met Gly Phe Ala Ala Val Met Ser Gly Pro Leu Val Arg Ser Ser Tyr 280 285 290 cgt gca ggc cgt ctg tac gcg cag gcc atg gag ttc cgt ggc gag gaa 1027 Arg Ala Gly Arg Leu Tyr Ala Gln Ala Met Glu Phe Arg Gly Glu Glu 295 300 305 atc cca gca cac ctc gcg cac ctg aag gat act tcc gga gga tcc acc 1075 Ile Pro Ala His Leu Ala His Leu Lys Asp Thr Ser Gly Gly Ser Thr 310 315 320 325 gcc cag gaa gca tct aca ctt ctg gag cgt tac ggt gct tcc gaa gac 1123 Ala Gln Glu Ala Ser Thr Leu Leu Glu Arg Tyr Gly Ala Ser Glu Asp 330 335 340 acc cca gtg gtg tcc ttc aac taagcccgaa gttttttaac cgc 1167 Thr Pro Val Val Ser Phe Asn 345 <210> 662 <211> 348 <212> PRT <213> Corynebacterium glutamicum <400> 662 Val Thr Ile Ala Pro Glu Gly Arg Arg Leu Leu Arg Val Glu Ala Arg 1 5 10 15 Asn Ser Glu Thr Pro Ile Glu Thr Lys Pro Arg Trp Ile Arg Asn Gln 20 25 30 Val Lys Asn Gly Pro Glu Tyr Gln Asp Met Lys Glu Arg Val Ala Gly 35 40 45 Ala Ser Leu His Thr Val Cys Gln Glu Ala Gly Cys Pro Asn Ile His 50 55 60 Glu Cys Trp Glu Ser Arg Glu Ala Thr Phe Leu Ile Gly Gly Ala Asn 65 70 75 80 Cys Ser Arg Arg Cys Asp Phe Cys Met Ile Asn Ser Ala Arg Pro Glu 85 90 95 Pro Leu Asp Arg Gly Glu Pro Leu Arg Val Ala Glu Ser Val Arg Glu 100 105 110 Met Gln Leu Asn Tyr Ser Thr Ile Thr Gly Val Thr Arg Asp Asp Leu 115 120 125 Asp Asp Glu Gly Ala Trp Leu Tyr Ser Glu Val Val Arg Lys Ile His 130 135 140 Glu Leu Asn Pro His Thr Gly Val Glu Asn Leu Val Pro Asp Phe Ser 145 150 155 160 Gly Lys Lys Asp Leu Leu Gln Glu Val Phe Glu Ser Arg Pro Glu Val 165 170 175 Phe Ala His Asn Val Glu Thr Val Pro Arg Ile Phe Lys Arg Ile Arg 180 185 190 Pro Ala Phe Arg Tyr Glu Arg Ser Leu Asp Val Ile Arg Gln Ala Arg 195 200 205 Asp Phe Gly Leu Val Thr Lys Ser Asn Leu Ile Leu Gly Met Gly Glu 210 215 220 Thr Lys Glu Glu Ile Thr Glu Ala Leu Gln Asp Leu His Asp Ala Gly 225 230 235 240 Cys Asp Ile Ile Thr Ile Thr Gln Tyr Leu Arg Pro Gly Pro Leu Phe 245 250 255 His Pro Ile Glu Arg Trp Val Lys Pro Glu Glu Phe Leu Glu His Ala 260 265 270 Asp Ala Ala Lys Glu Met Gly Phe Ala Ala Val Met Ser Gly Pro Leu 275 280 285 Val Arg Ser Ser Tyr Arg Ala Gly Arg Leu Tyr Ala Gln Ala Met Glu 290 295 300 Phe Arg Gly Glu Glu Ile Pro Ala His Leu Ala His Leu Lys Asp Thr 305 310 315 320 Ser Gly Gly Ser Thr Ala Gln Glu Ala Ser Thr Leu Leu Glu Arg Tyr 325 330 335 Gly Ala Ser Glu Asp Thr Pro Val Val Ser Phe Asn 340 345 <210> 663 <211> 876 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(853) <223> RXA01746 <400> 663 aaaccgccac tcccctttca ctggggagtg gcggttttgt cgtttcatgc atgcagtgtg 60 tgacttatca accttgttag ggctagggtg gatatctatc atg act gca cca aga 115 Met Thr Ala Pro Arg 1 5 gat cct ttt ttc ccc gca gat ctt tct atc cgc gcg tct gca gag ccc 163 Asp Pro Phe Phe Pro Ala Asp Leu Ser Ile Arg Ala Ser Ala Glu Pro 10 15 20 att gaa att cag cgg ttg ggt ttg atc gat tat caa gag gcc tgg gat 211 Ile Glu Ile Gln Arg Leu Gly Leu Ile Asp Tyr Gln Glu Ala Trp Asp 25 30 35 tat caa gca gag ctt gct acc cgt agg gct aat gat gaa atc cct gat 259 Tyr Gln Ala Glu Leu Ala Thr Arg Arg Ala Asn Asp Glu Ile Pro Asp 40 45 50 cag ctg ctt att ttg gag cac ccg tcg gtg tat acc gca ggt aag cgc 307 Gln Leu Leu Ile Leu Glu His Pro Ser Val Tyr Thr Ala Gly Lys Arg 55 60 65 acc cag ccg gaa gat ctt ccc acc aac gga ctg ccg gtg atc aat gct 355 Thr Gln Pro Glu Asp Leu Pro Thr Asn Gly Leu Pro Val Ile Asn Ala 70 75 80 85 gat cgt ggt ggt cgc atc acg tgg cat ggt cct ggc caa ttg gtg atc 403 Asp Arg Gly Gly Arg Ile Thr Trp His Gly Pro Gly Gln Leu Val Ile 90 95 100 tat ccg atc atc aaa tta gcc gat ccg atc gat gtg gtt gat tac gta 451 Tyr Pro Ile Ile Lys Leu Ala Asp Pro Ile Asp Val Val Asp Tyr Val 105 110 115 aga cgc ctc gag gaa gcg ctc atc caa gtt gtc ggc gat atg ggt gtt 499 Arg Arg Leu Glu Glu Ala Leu Ile Gln Val Val Gly Asp Met Gly Val 120 125 130 gcc ggc gct ggg cgc att gat ggg cgt tcg ggt gtg tgg gtg cca gct 547 Ala Gly Ala Gly Arg Ile Asp Gly Arg Ser Gly Val Trp Val Pro Ala 135 140 145 cat gat ggt tgg gtg gac agc aag gtt gcg gcc atc ggc att cga ata 595 His Asp Gly Trp Val Asp Ser Lys Val Ala Ala Ile Gly Ile Arg Ile 150 155 160 165 act cgt ggt gtt gca atg cac ggt gtg gcc atc aac tgc aac aac acg 643 Thr Arg Gly Val Ala Met His Gly Val Ala Ile Asn Cys Asn Asn Thr 170 175 180 ttg gat ttc tat gag cac atc att ccg tgt ggc att gct gat gca ggc 691 Leu Asp Phe Tyr Glu His Ile Ile Pro Cys Gly Ile Ala Asp Ala Gly 185 190 195 ttg agc aca ctc tcg agg gaa ctg aaa agg gac gtt tca gtt gag gaa 739 Leu Ser Thr Leu Ser Arg Glu Leu Lys Arg Asp Val Ser Val Glu Glu 200 205 210 tta gtc gag cca tcg atc cgc gca ttg gat gat gct ttg gct ggt cgg 787 Leu Val Glu Pro Ser Ile Arg Ala Leu Asp Asp Ala Leu Ala Gly Arg 215 220 225 ctg gtt gtt tct gat cat tct ttc ggc agc gcg ccc gac cca act aag 835 Leu Val Val Ser Asp His Ser Phe Gly Ser Ala Pro Asp Pro Thr Lys 230 235 240 245 aat ctc cct aaa cgg ggg tagtacgagg aattttgtcg gtg 876 Asn Leu Pro Lys Arg Gly 250 <210> 664 <211> 251 <212> PRT <213> Corynebacterium glutamicum <400> 664 Met Thr Ala Pro Arg Asp Pro Phe Phe Pro Ala Asp Leu Ser Ile Arg 1 5 10 15 Ala Ser Ala Glu Pro Ile Glu Ile Gln Arg Leu Gly Leu Ile Asp Tyr 20 25 30 Gln Glu Ala Trp Asp Tyr Gln Ala Glu Leu Ala Thr Arg Arg Ala Asn 35 40 45 Asp Glu Ile Pro Asp Gln Leu Leu Ile Leu Glu His Pro Ser Val Tyr 50 55 60 Thr Ala Gly Lys Arg Thr Gln Pro Glu Asp Leu Pro Thr Asn Gly Leu 65 70 75 80 Pro Val Ile Asn Ala Asp Arg Gly Gly Arg Ile Thr Trp His Gly Pro 85 90 95 Gly Gln Leu Val Ile Tyr Pro Ile Ile Lys Leu Ala Asp Pro Ile Asp 100 105 110 Val Val Asp Tyr Val Arg Arg Leu Glu Glu Ala Leu Ile Gln Val Val 115 120 125 Gly Asp Met Gly Val Ala Gly Ala Gly Arg Ile Asp Gly Arg Ser Gly 130 135 140 Val Trp Val Pro Ala His Asp Gly Trp Val Asp Ser Lys Val Ala Ala 145 150 155 160 Ile Gly Ile Arg Ile Thr Arg Gly Val Ala Met His Gly Val Ala Ile 165 170 175 Asn Cys Asn Asn Thr Leu Asp Phe Tyr Glu His Ile Ile Pro Cys Gly 180 185 190 Ile Ala Asp Ala Gly Leu Ser Thr Leu Ser Arg Glu Leu Lys Arg Asp 195 200 205 Val Ser Val Glu Glu Leu Val Glu Pro Ser Ile Arg Ala Leu Asp Asp 210 215 220 Ala Leu Ala Gly Arg Leu Val Val Ser Asp His Ser Phe Gly Ser Ala 225 230 235 240 Pro Asp Pro Thr Lys Asn Leu Pro Lys Arg Gly 245 250 <210> 665 <211> 1179 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1156) <223> RXA02106 <400> 665 ggtcgccgct tttcgacgcc cgcctgcggc gggatgactg tgatggaggg gcgcgtcgac 60 aagcaaaatc tctttagcaa attcggttac tgtggggcgc atg aat aac cat ttt 115 Met Asn Asn His Phe 1 5 gag ctc aaa gta cct ggt gga aag ctt gtc gtc gtt gat gtg acc acc 163 Glu Leu Lys Val Pro Gly Gly Lys Leu Val Val Val Asp Val Thr Thr 10 15 20 gat ctg gat tcc att gct gac gtg aag att tcc ggc gat ttc ttc ctc 211 Asp Leu Asp Ser Ile Ala Asp Val Lys Ile Ser Gly Asp Phe Phe Leu 25 30 35 gaa ccc gat gag gca ttc ttc gcc ctt ggc cgg gcg ctg cag ggg gcg 259 Glu Pro Asp Glu Ala Phe Phe Ala Leu Gly Arg Ala Leu Gln Gly Ala 40 45 50 tcg gtg ggt gat aac act gat cgt ttg cag gca aag ttg gat gca gcg 307 Ser Val Gly Asp Asn Thr Asp Arg Leu Gln Ala Lys Leu Asp Ala Ala 55 60 65 ttg gcg gaa tat gat gac gtt gag cta cac ggc ttt agc act gcg gat 355 Leu Ala Glu Tyr Asp Asp Val Glu Leu His Gly Phe Ser Thr Ala Asp 70 75 80 85 att gct tta gct gtg cgt cgg gca gtc acc ggc gcg caa gat ttc acc 403 Ile Ala Leu Ala Val Arg Arg Ala Val Thr Gly Ala Gln Asp Phe Thr 90 95 100 gat tat gaa tgg gaa atc ctg cac cca ggg gtg ctt cct acc cca ctt 451 Asp Tyr Glu Trp Glu Ile Leu His Pro Gly Val Leu Pro Thr Pro Leu 105 110 115 aac gtt gcg ttg gat gag ctc ctt ttg gac caa gtt gcc agt ggt cag 499 Asn Val Ala Leu Asp Glu Leu Leu Leu Asp Gln Val Ala Ser Gly Gln 120 125 130 cgt ggc ccg acg atg cgc att tgg gat tgg gat gat cgc gcc aca gtg 547 Arg Gly Pro Thr Met Arg Ile Trp Asp Trp Asp Asp Arg Ala Thr Val 135 140 145 atc ggt agt ttc cag tca tat gtc aat gaa atc aac caa gaa ggc gtt 595 Ile Gly Ser Phe Gln Ser Tyr Val Asn Glu Ile Asn Gln Glu Gly Val 150 155 160 165 aat gaa cat ggt gtg acc gtg gta cga cgc atg tct ggt ggc ggt gca 643 Asn Glu His Gly Val Thr Val Val Arg Arg Met Ser Gly Gly Gly Ala 170 175 180 atg ttt atg gag ggc ggc aac tgc atc acc tat tcc ctg tat gca ccg 691 Met Phe Met Glu Gly Gly Asn Cys Ile Thr Tyr Ser Leu Tyr Ala Pro 185 190 195 gaa tct ctc gtt gct ggt ttg agc tat gag cag tcc tat gaa tat ttg 739 Glu Ser Leu Val Ala Gly Leu Ser Tyr Glu Gln Ser Tyr Glu Tyr Leu 200 205 210 gat cgt tgg gtg att gct gcg ctg aag aca cac gat gtt gac gct tgg 787 Asp Arg Trp Val Ile Ala Ala Leu Lys Thr His Asp Val Asp Ala Trp 215 220 225 tac gtg cct atc aat gac atc acc tcc acc ggc gga aaa atc ggt ggc 835 Tyr Val Pro Ile Asn Asp Ile Thr Ser Thr Gly Gly Lys Ile Gly Gly 230 235 240 245 gct gca cag aaa cgt cgc agt ggc gca gtc ctc cac cac gtg acc atg 883 Ala Ala Gln Lys Arg Arg Ser Gly Ala Val Leu His His Val Thr Met 250 255 260 tcc tat gac atc gat gcg gac atg atg acc cag gtg ttg cgc att gga 931 Ser Tyr Asp Ile Asp Ala Asp Met Met Thr Gln Val Leu Arg Ile Gly 265 270 275 aag gtg aag att tcc gac aag ggt ctt cgc agc gca aag aag cgc gtt 979 Lys Val Lys Ile Ser Asp Lys Gly Leu Arg Ser Ala Lys Lys Arg Val 280 285 290 gat cct ctg cgc cgc caa aca ggt gca tca cgt gag caa atc atc gac 1027 Asp Pro Leu Arg Arg Gln Thr Gly Ala Ser Arg Glu Gln Ile Ile Asp 295 300 305 acc cta aag tcc aca ttc agt gct agg tac ggc gcg caa gaa gta gag 1075 Thr Leu Lys Ser Thr Phe Ser Ala Arg Tyr Gly Ala Gln Glu Val Glu 310 315 320 325 ctc agc gat gaa gat ttc gcg gca ggc cac gac cta gta aaa acc aaa 1123 Leu Ser Asp Glu Asp Phe Ala Ala Gly His Asp Leu Val Lys Thr Lys 330 335 340 tac gcc acc gag gag tgg act aag cga gtt caa tagtttctat ggatctgcac 1176 Tyr Ala Thr Glu Glu Trp Thr Lys Arg Val Gln 345 350 aag 1179 <210> 666 <211> 352 <212> PRT <213> Corynebacterium glutamicum <400> 666 Met Asn Asn His Phe Glu Leu Lys Val Pro Gly Gly Lys Leu Val Val 1 5 10 15 Val Asp Val Thr Thr Asp Leu Asp Ser Ile Ala Asp Val Lys Ile Ser 20 25 30 Gly Asp Phe Phe Leu Glu Pro Asp Glu Ala Phe Phe Ala Leu Gly Arg 35 40 45 Ala Leu Gln Gly Ala Ser Val Gly Asp Asn Thr Asp Arg Leu Gln Ala 50 55 60 Lys Leu Asp Ala Ala Leu Ala Glu Tyr Asp Asp Val Glu Leu His Gly 65 70 75 80 Phe Ser Thr Ala Asp Ile Ala Leu Ala Val Arg Arg Ala Val Thr Gly 85 90 95 Ala Gln Asp Phe Thr Asp Tyr Glu Trp Glu Ile Leu His Pro Gly Val 100 105 110 Leu Pro Thr Pro Leu Asn Val Ala Leu Asp Glu Leu Leu Leu Asp Gln 115 120 125 Val Ala Ser Gly Gln Arg Gly Pro Thr Met Arg Ile Trp Asp Trp Asp 130 135 140 Asp Arg Ala Thr Val Ile Gly Ser Phe Gln Ser Tyr Val Asn Glu Ile 145 150 155 160 Asn Gln Glu Gly Val Asn Glu His Gly Val Thr Val Val Arg Arg Met 165 170 175 Ser Gly Gly Gly Ala Met Phe Met Glu Gly Gly Asn Cys Ile Thr Tyr 180 185 190 Ser Leu Tyr Ala Pro Glu Ser Leu Val Ala Gly Leu Ser Tyr Glu Gln 195 200 205 Ser Tyr Glu Tyr Leu Asp Arg Trp Val Ile Ala Ala Leu Lys Thr His 210 215 220 Asp Val Asp Ala Trp Tyr Val Pro Ile Asn Asp Ile Thr Ser Thr Gly 225 230 235 240 Gly Lys Ile Gly Gly Ala Ala Gln Lys Arg Arg Ser Gly Ala Val Leu 245 250 255 His His Val Thr Met Ser Tyr Asp Ile Asp Ala Asp Met Met Thr Gln 260 265 270 Val Leu Arg Ile Gly Lys Val Lys Ile Ser Asp Lys Gly Leu Arg Ser 275 280 285 Ala Lys Lys Arg Val Asp Pro Leu Arg Arg Gln Thr Gly Ala Ser Arg 290 295 300 Glu Gln Ile Ile Asp Thr Leu Lys Ser Thr Phe Ser Ala Arg Tyr Gly 305 310 315 320 Ala Gln Glu Val Glu Leu Ser Asp Glu Asp Phe Ala Ala Gly His Asp 325 330 335 Leu Val Lys Thr Lys Tyr Ala Thr Glu Glu Trp Thr Lys Arg Val Gln 340 345 350 <210> 667 <211> 403 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(403) <223> RXS01183 <400> 667 cttgatatga cccgaacacc acacatcaca aattgaatcg gtatcctttg gggtattagt 60 ttccgtttta acgacacgac ttgcgaggag tcttaaaata atg gcg ttc tcc gta 115 Met Ala Phe Ser Val 1 5 gag atg ccc gag ctg ggc gaa tca gta acc gaa ggc acg atc acc cag 163 Glu Met Pro Glu Leu Gly Glu Ser Val Thr Glu Gly Thr Ile Thr Gln 10 15 20 tgg ttg aag tct gtt ggt gac act gtt gag gta gat gag ccg ttg ctc 211 Trp Leu Lys Ser Val Gly Asp Thr Val Glu Val Asp Glu Pro Leu Leu 25 30 35 gag gtc tca act gac aag gtc gac acc gag att ccc tct cct gtc gcc 259 Glu Val Ser Thr Asp Lys Val Asp Thr Glu Ile Pro Ser Pro Val Ala 40 45 50 ggt gtc atc cta gag att aag gct gaa gag gat gac acc gtc gac gtc 307 Gly Val Ile Leu Glu Ile Lys Ala Glu Glu Asp Asp Thr Val Asp Val 55 60 65 ggc ggt gtc att gca ata atc ggc gat gct gat gag act cct gcc aac 355 Gly Gly Val Ile Ala Ile Ile Gly Asp Ala Asp Glu Thr Pro Ala Asn 70 75 80 85 gaa gct cct gcc gac gag gca cca gct cct gcc gaa gag gaa gaa cca 403 Glu Ala Pro Ala Asp Glu Ala Pro Ala Pro Ala Glu Glu Glu Glu Pro 90 95 100 <210> 668 <211> 101 <212> PRT <213> Corynebacterium glutamicum <400> 668 Met Ala Phe Ser Val Glu Met Pro Glu Leu Gly Glu Ser Val Thr Glu 1 5 10 15 Gly Thr Ile Thr Gln Trp Leu Lys Ser Val Gly Asp Thr Val Glu Val 20 25 30 Asp Glu Pro Leu Leu Glu Val Ser Thr Asp Lys Val Asp Thr Glu Ile 35 40 45 Pro Ser Pro Val Ala Gly Val Ile Leu Glu Ile Lys Ala Glu Glu Asp 50 55 60 Asp Thr Val Asp Val Gly Gly Val Ile Ala Ile Ile Gly Asp Ala Asp 65 70 75 80 Glu Thr Pro Ala Asn Glu Ala Pro Ala Asp Glu Ala Pro Ala Pro Ala 85 90 95 Glu Glu Glu Glu Pro 100 <210> 669 <211> 1305 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1282) <223> RXS01260 <400> 669 ctaaacgtgg gctgcattcc ttccaaagtc tctgatcaaa aacgctgaag ttgcccatac 60 ctttacccat gagaagaaga ccttcggcat caatggcgaa gtg acc ttc aac tat 115 Val Thr Phe Asn Tyr 1 5 gag gat gct cac aag cgt tcc cgt ggc gtt tcc gac aag atc gtt gga 163 Glu Asp Ala His Lys Arg Ser Arg Gly Val Ser Asp Lys Ile Val Gly 10 15 20 ggc gtt cat tac ttg atg aag aag aac aag atc atc gaa att cat ggt 211 Gly Val His Tyr Leu Met Lys Lys Asn Lys Ile Ile Glu Ile His Gly 25 30 35 ctt gga aac ttc aag gat gct aag act ctt gag gtc acc gac ggt aag 259 Leu Gly Asn Phe Lys Asp Ala Lys Thr Leu Glu Val Thr Asp Gly Lys 40 45 50 gat gct ggc aag acc atc acc ttt gat gac tgc atc atc gca acc ggt 307 Asp Ala Gly Lys Thr Ile Thr Phe Asp Asp Cys Ile Ile Ala Thr Gly 55 60 65 tcg gta gtc aac acc ctc cgt ggc gtt gac ttc tca gag aac gtt gtg 355 Ser Val Val Asn Thr Leu Arg Gly Val Asp Phe Ser Glu Asn Val Val 70 75 80 85 tct ttt gaa gag cag att ctt aac cct gtt gcg cca aag aag atg gtc 403 Ser Phe Glu Glu Gln Ile Leu Asn Pro Val Ala Pro Lys Lys Met Val 90 95 100 att gtt ggt gca ggc gca att gga atg gaa ttc gcc tac gtt ctt ggt 451 Ile Val Gly Ala Gly Ala Ile Gly Met Glu Phe Ala Tyr Val Leu Gly 105 110 115 aac tac ggt gta gat gta acc gtc atc gag ttc atg gat cgt gtg ctt 499 Asn Tyr Gly Val Asp Val Thr Val Ile Glu Phe Met Asp Arg Val Leu 120 125 130 cca aat gaa gat gct gaa gtc tcc aag gtt att gca aag gcc tac aag 547 Pro Asn Glu Asp Ala Glu Val Ser Lys Val Ile Ala Lys Ala Tyr Lys 135 140 145 aag atg ggc gtt aag ctt ctt cct ggc cat gca acc act gct gtt cgg 595 Lys Met Gly Val Lys Leu Leu Pro Gly His Ala Thr Thr Ala Val Arg 150 155 160 165 gac aac ggt gac ttt gtc gag gtt gat tac cag aag aag ggc tct gac 643 Asp Asn Gly Asp Phe Val Glu Val Asp Tyr Gln Lys Lys Gly Ser Asp 170 175 180 aag aca gag act ctt act gtt gat cga gtc atg gtt tcc gtt ggt ttc 691 Lys Thr Glu Thr Leu Thr Val Asp Arg Val Met Val Ser Val Gly Phe 185 190 195 cgt cca cgc gtt gag gga ttt ggt ctt gaa aac act ggc gtt aag ctc 739 Arg Pro Arg Val Glu Gly Phe Gly Leu Glu Asn Thr Gly Val Lys Leu 200 205 210 acc gag cgt ggc gca atc gag atc gat gat tac atg cgt acc aac gtc 787 Thr Glu Arg Gly Ala Ile Glu Ile Asp Asp Tyr Met Arg Thr Asn Val 215 220 225 gat ggc att tac gcc atc ggt gac gtg acc gcc aag ctt cag ctt gct 835 Asp Gly Ile Tyr Ala Ile Gly Asp Val Thr Ala Lys Leu Gln Leu Ala 230 235 240 245 cac gtc gca gaa gca cag ggc att gtt gcc gca gag act att gct ggt 883 His Val Ala Glu Ala Gln Gly Ile Val Ala Ala Glu Thr Ile Ala Gly 250 255 260 gca gaa act cag act ctt ggt gat tac atg atg atg cca cgt gca acc 931 Ala Glu Thr Gln Thr Leu Gly Asp Tyr Met Met Met Pro Arg Ala Thr 265 270 275 ttc tgc aac cca cag gtt tct tcc ttt ggt tac acc gaa gag cag gcc 979 Phe Cys Asn Pro Gln Val Ser Ser Phe Gly Tyr Thr Glu Glu Gln Ala 280 285 290 aag gag aag tgg cca gat cgt gag atc aag gtt gct tcc ttc cca ttc 1027 Lys Glu Lys Trp Pro Asp Arg Glu Ile Lys Val Ala Ser Phe Pro Phe 295 300 305 tct gca aac ggt aaa gca gtt ggc ctg gca gaa act gat ggt ttc gca 1075 Ser Ala Asn Gly Lys Ala Val Gly Leu Ala Glu Thr Asp Gly Phe Ala 310 315 320 325 aag atc gtt gct gat gca gaa ttc ggt gag ctg ctc ggt gca cac ctg 1123 Lys Ile Val Ala Asp Ala Glu Phe Gly Glu Leu Leu Gly Ala His Leu 330 335 340 gtt gga gca aat gca tca gag ctc atc aat gaa ttg gtg ctt gct cag 1171 Val Gly Ala Asn Ala Ser Glu Leu Ile Asn Glu Leu Val Leu Ala Gln 345 350 355 aac tgg gat ctc acc act gaa gag atc tct cgt agc gtc cat att cac 1219 Asn Trp Asp Leu Thr Thr Glu Glu Ile Ser Arg Ser Val His Ile His 360 365 370 cca acg cta tct gag gca gtt aag gaa gct gca cac ggt atc tct gga 1267 Pro Thr Leu Ser Glu Ala Val Lys Glu Ala Ala His Gly Ile Ser Gly 375 380 385 cac atg atc aac ttc tagaatccac ctcgttggcc ctg 1305 His Met Ile Asn Phe 390 <210> 670 <211> 394 <212> PRT <213> Corynebacterium glutamicum <400> 670 Val Thr Phe Asn Tyr Glu Asp Ala His Lys Arg Ser Arg Gly Val Ser 1 5 10 15 Asp Lys Ile Val Gly Gly Val His Tyr Leu Met Lys Lys Asn Lys Ile 20 25 30 Ile Glu Ile His Gly Leu Gly Asn Phe Lys Asp Ala Lys Thr Leu Glu 35 40 45 Val Thr Asp Gly Lys Asp Ala Gly Lys Thr Ile Thr Phe Asp Asp Cys 50 55 60 Ile Ile Ala Thr Gly Ser Val Val Asn Thr Leu Arg Gly Val Asp Phe 65 70 75 80 Ser Glu Asn Val Val Ser Phe Glu Glu Gln Ile Leu Asn Pro Val Ala 85 90 95 Pro Lys Lys Met Val Ile Val Gly Ala Gly Ala Ile Gly Met Glu Phe 100 105 110 Ala Tyr Val Leu Gly Asn Tyr Gly Val Asp Val Thr Val Ile Glu Phe 115 120 125 Met Asp Arg Val Leu Pro Asn Glu Asp Ala Glu Val Ser Lys Val Ile 130 135 140 Ala Lys Ala Tyr Lys Lys Met Gly Val Lys Leu Leu Pro Gly His Ala 145 150 155 160 Thr Thr Ala Val Arg Asp Asn Gly Asp Phe Val Glu Val Asp Tyr Gln 165 170 175 Lys Lys Gly Ser Asp Lys Thr Glu Thr Leu Thr Val Asp Arg Val Met 180 185 190 Val Ser Val Gly Phe Arg Pro Arg Val Glu Gly Phe Gly Leu Glu Asn 195 200 205 Thr Gly Val Lys Leu Thr Glu Arg Gly Ala Ile Glu Ile Asp Asp Tyr 210 215 220 Met Arg Thr Asn Val Asp Gly Ile Tyr Ala Ile Gly Asp Val Thr Ala 225 230 235 240 Lys Leu Gln Leu Ala His Val Ala Glu Ala Gln Gly Ile Val Ala Ala 245 250 255 Glu Thr Ile Ala Gly Ala Glu Thr Gln Thr Leu Gly Asp Tyr Met Met 260 265 270 Met Pro Arg Ala Thr Phe Cys Asn Pro Gln Val Ser Ser Phe Gly Tyr 275 280 285 Thr Glu Glu Gln Ala Lys Glu Lys Trp Pro Asp Arg Glu Ile Lys Val 290 295 300 Ala Ser Phe Pro Phe Ser Ala Asn Gly Lys Ala Val Gly Leu Ala Glu 305 310 315 320 Thr Asp Gly Phe Ala Lys Ile Val Ala Asp Ala Glu Phe Gly Glu Leu 325 330 335 Leu Gly Ala His Leu Val Gly Ala Asn Ala Ser Glu Leu Ile Asn Glu 340 345 350 Leu Val Leu Ala Gln Asn Trp Asp Leu Thr Thr Glu Glu Ile Ser Arg 355 360 365 Ser Val His Ile His Pro Thr Leu Ser Glu Ala Val Lys Glu Ala Ala 370 375 380 His Gly Ile Ser Gly His Met Ile Asn Phe 385 390 <210> 671 <211> 294 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(271) <223> RXS01261 <400> 671 gtgggtgttt ttcattttct tccactctaa aattaagtat ggaaaaccaa ccgcacccgg 60 atgcacgaca atgacccact aaacacgtat ccttgaatgc gtg act gaa cat tat 115 Val Thr Glu His Tyr 1 5 gac gta gta gta ctc gga gcc ggc ccc ggt ggc tat gtc tcc gcc atc 163 Asp Val Val Val Leu Gly Ala Gly Pro Gly Gly Tyr Val Ser Ala Ile 10 15 20 cgt gca gcg cag ctt ggc aag aag gtt gct gta att gag aag cag tac 211 Arg Ala Ala Gln Leu Gly Lys Lys Val Ala Val Ile Glu Lys Gln Tyr 25 30 35 tgg ggt ggt gtt tgc cta aac gtg ggc tgc att cct tcc aaa gtc tct 259 Trp Gly Gly Val Cys Leu Asn Val Gly Cys Ile Pro Ser Lys Val Ser 40 45 50 gat caa aaa cgc tgaagttgcc cataccttta ccc 294 Asp Gln Lys Arg 55 <210> 672 <211> 57 <212> PRT <213> Corynebacterium glutamicum <400> 672 Val Thr Glu His Tyr Asp Val Val Val Leu Gly Ala Gly Pro Gly Gly 1 5 10 15 Tyr Val Ser Ala Ile Arg Ala Ala Gln Leu Gly Lys Lys Val Ala Val 20 25 30 Ile Glu Lys Gln Tyr Trp Gly Gly Val Cys Leu Asn Val Gly Cys Ile 35 40 45 Pro Ser Lys Val Ser Asp Gln Lys Arg 50 55 <210> 673 <211> 1005 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(982) <223> RXA02717 <400> 673 aggcatgtcc ctaacgaaca tcccagcctc atctcaatgg gcaattagcg acgttttgaa 60 gcgtccttca cccggccgag tacctttttc tgtcgagttt atg cca ccc cgc gac 115 Met Pro Pro Arg Asp 1 5 gat gca gct gaa gag cgt ctt tac cgc gca gca gag gtc ttc cat gac 163 Asp Ala Ala Glu Glu Arg Leu Tyr Arg Ala Ala Glu Val Phe His Asp 10 15 20 ctc ggt gca tcg ttt gtc tcc gtg act tat ggt gct ggc gga tca acc 211 Leu Gly Ala Ser Phe Val Ser Val Thr Tyr Gly Ala Gly Gly Ser Thr 25 30 35 cgt gag aga acc tca cgt att gct cga cga tta gcg aaa caa ccg ttg 259 Arg Glu Arg Thr Ser Arg Ile Ala Arg Arg Leu Ala Lys Gln Pro Leu 40 45 50 acc act ctg gtg cac ctg acc ctg gtt aac cac act cgc gaa gag atg 307 Thr Thr Leu Val His Leu Thr Leu Val Asn His Thr Arg Glu Glu Met 55 60 65 aag gca att ctt cgg gaa tac cta gag ctg gga tta aca aac ctg ttg 355 Lys Ala Ile Leu Arg Glu Tyr Leu Glu Leu Gly Leu Thr Asn Leu Leu 70 75 80 85 gcg ctt cga gga gat ccg cct gga gac cca tta ggc gat tgg gtg agc 403 Ala Leu Arg Gly Asp Pro Pro Gly Asp Pro Leu Gly Asp Trp Val Ser 90 95 100 acc gat gga gga ctg aac tat gcc tct gag ctc atc gat ctt att aag 451 Thr Asp Gly Gly Leu Asn Tyr Ala Ser Glu Leu Ile Asp Leu Ile Lys 105 110 115 tcc act cct gag ttc cgg gaa ttc gac ctc ggt atc gcc tcc ttc ccc 499 Ser Thr Pro Glu Phe Arg Glu Phe Asp Leu Gly Ile Ala Ser Phe Pro 120 125 130 gaa ggg cat ttc cgg gcg aaa act cta gaa gaa gac acc aaa tac act 547 Glu Gly His Phe Arg Ala Lys Thr Leu Glu Glu Asp Thr Lys Tyr Thr 135 140 145 ctg gcg aag ctg cgt gga ggg gca gag tac tcc atc acg cag atg ttc 595 Leu Ala Lys Leu Arg Gly Gly Ala Glu Tyr Ser Ile Thr Gln Met Phe 150 155 160 165 ttt gat gtg gaa gac tac ctg cga ctt cgt gat cgc ctt gtc gct gca 643 Phe Asp Val Glu Asp Tyr Leu Arg Leu Arg Asp Arg Leu Val Ala Ala 170 175 180 gac ccc att cat ggt gcg aag cca atc att cct ggc atc atg ccc att 691 Asp Pro Ile His Gly Ala Lys Pro Ile Ile Pro Gly Ile Met Pro Ile 185 190 195 acg agc ctg cgg tct gtg cgt cga cag gtc gaa ctc tct ggt gct caa 739 Thr Ser Leu Arg Ser Val Arg Arg Gln Val Glu Leu Ser Gly Ala Gln 200 205 210 ttg ccg agc caa cta gaa gaa tca ctt gtt cga gct gca aac ggc aat 787 Leu Pro Ser Gln Leu Glu Glu Ser Leu Val Arg Ala Ala Asn Gly Asn 215 220 225 gaa gaa gcg aac aaa gac gag atc cgc aag gtg ggc att gaa tat tcc 835 Glu Glu Ala Asn Lys Asp Glu Ile Arg Lys Val Gly Ile Glu Tyr Ser 230 235 240 245 acc aat atg gca gag cga ctc att gcc gaa ggt gcg gaa gat ctg cac 883 Thr Asn Met Ala Glu Arg Leu Ile Ala Glu Gly Ala Glu Asp Leu His 250 255 260 ttc atg acg ctt aac ttc acc cgt gca acc caa gaa gtg ttg tac aac 931 Phe Met Thr Leu Asn Phe Thr Arg Ala Thr Gln Glu Val Leu Tyr Asn 265 270 275 ctt ggc atg gcg cct gct tgg gga gca gag cac ggc caa gac gcg gtg 979 Leu Gly Met Ala Pro Ala Trp Gly Ala Glu His Gly Gln Asp Ala Val 280 285 290 cgt taagccctct taggaatcat gaa 1005 Arg <210> 674 <211> 294 <212> PRT <213> Corynebacterium glutamicum <400> 674 Met Pro Pro Arg Asp Asp Ala Ala Glu Glu Arg Leu Tyr Arg Ala Ala 1 5 10 15 Glu Val Phe His Asp Leu Gly Ala Ser Phe Val Ser Val Thr Tyr Gly 20 25 30 Ala Gly Gly Ser Thr Arg Glu Arg Thr Ser Arg Ile Ala Arg Arg Leu 35 40 45 Ala Lys Gln Pro Leu Thr Thr Leu Val His Leu Thr Leu Val Asn His 50 55 60 Thr Arg Glu Glu Met Lys Ala Ile Leu Arg Glu Tyr Leu Glu Leu Gly 65 70 75 80 Leu Thr Asn Leu Leu Ala Leu Arg Gly Asp Pro Pro Gly Asp Pro Leu 85 90 95 Gly Asp Trp Val Ser Thr Asp Gly Gly Leu Asn Tyr Ala Ser Glu Leu 100 105 110 Ile Asp Leu Ile Lys Ser Thr Pro Glu Phe Arg Glu Phe Asp Leu Gly 115 120 125 Ile Ala Ser Phe Pro Glu Gly His Phe Arg Ala Lys Thr Leu Glu Glu 130 135 140 Asp Thr Lys Tyr Thr Leu Ala Lys Leu Arg Gly Gly Ala Glu Tyr Ser 145 150 155 160 Ile Thr Gln Met Phe Phe Asp Val Glu Asp Tyr Leu Arg Leu Arg Asp 165 170 175 Arg Leu Val Ala Ala Asp Pro Ile His Gly Ala Lys Pro Ile Ile Pro 180 185 190 Gly Ile Met Pro Ile Thr Ser Leu Arg Ser Val Arg Arg Gln Val Glu 195 200 205 Leu Ser Gly Ala Gln Leu Pro Ser Gln Leu Glu Glu Ser Leu Val Arg 210 215 220 Ala Ala Asn Gly Asn Glu Glu Ala Asn Lys Asp Glu Ile Arg Lys Val 225 230 235 240 Gly Ile Glu Tyr Ser Thr Asn Met Ala Glu Arg Leu Ile Ala Glu Gly 245 250 255 Ala Glu Asp Leu His Phe Met Thr Leu Asn Phe Thr Arg Ala Thr Gln 260 265 270 Glu Val Leu Tyr Asn Leu Gly Met Ala Pro Ala Trp Gly Ala Glu His 275 280 285 Gly Gln Asp Ala Val Arg 290 <210> 675 <211> 601 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(601) <223> RXN02027 <400> 675 tcacgtgctc atcgataggc aaactcatgg aaccaagagt acctgccccc gcaaccccaa 60 tcgtcgtacc cctccgaaaa taacggttat ccttagattt atg agc caa act aag 115 Met Ser Gln Thr Lys 1 5 cag gaa ctg cgc acg aag ctt cgg gaa gcg cgc acc aat atg gat gag 163 Gln Glu Leu Arg Thr Lys Leu Arg Glu Ala Arg Thr Asn Met Asp Glu 10 15 20 gct tct cgc acg cga gaa aac gca gcc atc att gcc aac gtt tct tat 211 Ala Ser Arg Thr Arg Glu Asn Ala Ala Ile Ile Ala Asn Val Ser Tyr 25 30 35 tac atc cgc tca aag cag cca aaa agg att gcc gct tac gtg ccg gtg 259 Tyr Ile Arg Ser Lys Gln Pro Lys Arg Ile Ala Ala Tyr Val Pro Val 40 45 50 cgt acc gaa cct ggt ggg cga ttg ctt ctt gac gcc ctc cac gcc gaa 307 Arg Thr Glu Pro Gly Gly Arg Leu Leu Leu Asp Ala Leu His Ala Glu 55 60 65 act tcc gcg ctt att ttg cca gtc tcc ctc gag gat cga cgc ctc gac 355 Thr Ser Ala Leu Ile Leu Pro Val Ser Leu Glu Asp Arg Arg Leu Asp 70 75 80 85 tgg gct ctt tat gaa ggc cca acc agc ctt gtt cct ggc gca ttt ggc 403 Trp Ala Leu Tyr Glu Gly Pro Thr Ser Leu Val Pro Gly Ala Phe Gly 90 95 100 atc cag gaa ccc ggt ggc act cgc ctt gga cct gaa gct ctc aac ttc 451 Ile Gln Glu Pro Gly Gly Thr Arg Leu Gly Pro Glu Ala Leu Asn Phe 105 110 115 tgc gac ctt gtc atc gcc ccc gca ctg gca tgc acc ccc agt gga atc 499 Cys Asp Leu Val Ile Ala Pro Ala Leu Ala Cys Thr Pro Ser Gly Ile 120 125 130 agg cta ggt aaa ggt ggc ggt ttc tac gac cgc gct cta gcc acc gga 547 Arg Leu Gly Lys Gly Gly Gly Phe Tyr Asp Arg Ala Leu Ala Thr Gly 135 140 145 gtc aag gct gac gtg att act ttg ctc ttc aac gga gaa atc cgc gac 595 Val Lys Ala Asp Val Ile Thr Leu Leu Phe Asn Gly Glu Ile Arg Asp 150 155 160 165 gat atc 601 Asp Ile <210> 676 <211> 167 <212> PRT <213> Corynebacterium glutamicum <400> 676 Met Ser Gln Thr Lys Gln Glu Leu Arg Thr Lys Leu Arg Glu Ala Arg 1 5 10 15 Thr Asn Met Asp Glu Ala Ser Arg Thr Arg Glu Asn Ala Ala Ile Ile 20 25 30 Ala Asn Val Ser Tyr Tyr Ile Arg Ser Lys Gln Pro Lys Arg Ile Ala 35 40 45 Ala Tyr Val Pro Val Arg Thr Glu Pro Gly Gly Arg Leu Leu Leu Asp 50 55 60 Ala Leu His Ala Glu Thr Ser Ala Leu Ile Leu Pro Val Ser Leu Glu 65 70 75 80 Asp Arg Arg Leu Asp Trp Ala Leu Tyr Glu Gly Pro Thr Ser Leu Val 85 90 95 Pro Gly Ala Phe Gly Ile Gln Glu Pro Gly Gly Thr Arg Leu Gly Pro 100 105 110 Glu Ala Leu Asn Phe Cys Asp Leu Val Ile Ala Pro Ala Leu Ala Cys 115 120 125 Thr Pro Ser Gly Ile Arg Leu Gly Lys Gly Gly Gly Phe Tyr Asp Arg 130 135 140 Ala Leu Ala Thr Gly Val Lys Ala Asp Val Ile Thr Leu Leu Phe Asn 145 150 155 160 Gly Glu Ile Arg Asp Asp Ile 165 <210> 677 <211> 595 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(595) <223> FRXA02027 <400> 677 tcacgtgctc atcgataggc aaactcatgg aaccaagagt acctgccccc gcaaccccaa 60 tcgtcgtacc cctccgaaaa taacggttat ccttagattt atg agc caa act aag 115 Met Ser Gln Thr Lys 1 5 cag gaa ctg cgc acg aag ctt cgg gaa gcg cgc acc aat atg gat gag 163 Gln Glu Leu Arg Thr Lys Leu Arg Glu Ala Arg Thr Asn Met Asp Glu 10 15 20 gct tct cgc acg cga gaa aac gca gcc atc att gcc aac gtt tct tat 211 Ala Ser Arg Thr Arg Glu Asn Ala Ala Ile Ile Ala Asn Val Ser Tyr 25 30 35 tac atc cgc tca aag cag cca aaa agg att gcc gct tac gtg ccg gtg 259 Tyr Ile Arg Ser Lys Gln Pro Lys Arg Ile Ala Ala Tyr Val Pro Val 40 45 50 cgt acc gaa cct ggt ggg cga ttg ctt ctt gac gcc ctc cac gcc gaa 307 Arg Thr Glu Pro Gly Gly Arg Leu Leu Leu Asp Ala Leu His Ala Glu 55 60 65 act tcc gcg ctt att ttg cca gtc tcc ctc gag gat cga cgc ctc gac 355 Thr Ser Ala Leu Ile Leu Pro Val Ser Leu Glu Asp Arg Arg Leu Asp 70 75 80 85 tgg gct ctt tat gaa ggc cca acc agc ctt gtt cct ggc gca ttt ggc 403 Trp Ala Leu Tyr Glu Gly Pro Thr Ser Leu Val Pro Gly Ala Phe Gly 90 95 100 atc cag gaa ccc ggt ggc act cgc ctt gga cct gaa gct ctc aac ttc 451 Ile Gln Glu Pro Gly Gly Thr Arg Leu Gly Pro Glu Ala Leu Asn Phe 105 110 115 tgc gac ctt gtc atc gcc ccc gca ctg gca tgc acc ccc agt gga atc 499 Cys Asp Leu Val Ile Ala Pro Ala Leu Ala Cys Thr Pro Ser Gly Ile 120 125 130 agg cta ggt aaa ggt ggc ggt ttc tac gac cgc gct cta gcc acc gga 547 Arg Leu Gly Lys Gly Gly Gly Phe Tyr Asp Arg Ala Leu Ala Thr Gly 135 140 145 gtc aag gct gac gtg att act ttg ctc ttc aac gga gaa atc cgc gac 595 Val Lys Ala Asp Val Ile Thr Leu Leu Phe Asn Gly Glu Ile Arg Asp 150 155 160 165 <210> 678 <211> 165 <212> PRT <213> Corynebacterium glutamicum <400> 678 Met Ser Gln Thr Lys Gln Glu Leu Arg Thr Lys Leu Arg Glu Ala Arg 1 5 10 15 Thr Asn Met Asp Glu Ala Ser Arg Thr Arg Glu Asn Ala Ala Ile Ile 20 25 30 Ala Asn Val Ser Tyr Tyr Ile Arg Ser Lys Gln Pro Lys Arg Ile Ala 35 40 45 Ala Tyr Val Pro Val Arg Thr Glu Pro Gly Gly Arg Leu Leu Leu Asp 50 55 60 Ala Leu His Ala Glu Thr Ser Ala Leu Ile Leu Pro Val Ser Leu Glu 65 70 75 80 Asp Arg Arg Leu Asp Trp Ala Leu Tyr Glu Gly Pro Thr Ser Leu Val 85 90 95 Pro Gly Ala Phe Gly Ile Gln Glu Pro Gly Gly Thr Arg Leu Gly Pro 100 105 110 Glu Ala Leu Asn Phe Cys Asp Leu Val Ile Ala Pro Ala Leu Ala Cys 115 120 125 Thr Pro Ser Gly Ile Arg Leu Gly Lys Gly Gly Gly Phe Tyr Asp Arg 130 135 140 Ala Leu Ala Thr Gly Val Lys Ala Asp Val Ile Thr Leu Leu Phe Asn 145 150 155 160 Gly Glu Ile Arg Asp 165 <210> 679 <211> 579 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(556) <223> RXA00106 <400> 679 tggagctcaa caaggcagcg tacatgtttg agtacagctt cgatgacatc accgtgtccg 60 gctacgatcc acacccattg atccgcggca aggtcgccgt atg atc ggt gcg att 115 Met Ile Gly Ala Ile 1 5 tgg gca caa ggc cgt gac ggc atc atc ggc gac ggc acc gac atg ccc 163 Trp Ala Gln Gly Arg Asp Gly Ile Ile Gly Asp Gly Thr Asp Met Pro 10 15 20 tgg cac atc ccg gaa gac ctc aaa cac ttc aag aaa acc acc atg ggc 211 Trp His Ile Pro Glu Asp Leu Lys His Phe Lys Lys Thr Thr Met Gly 25 30 35 cag ccg gtc atc atg ggt cgt cgc acg tgg gag tct ttg ccg ttc aag 259 Gln Pro Val Ile Met Gly Arg Arg Thr Trp Glu Ser Leu Pro Phe Lys 40 45 50 ccg ctt ccc ggc cgc gag aac ttc att ctc tcc tca cgc gag ccc ggc 307 Pro Leu Pro Gly Arg Glu Asn Phe Ile Leu Ser Ser Arg Glu Pro Gly 55 60 65 gac tgg tcc gcc ggc ggc aca gtg gtc acc gaa atc cct aaa agc ggc 355 Asp Trp Ser Ala Gly Gly Thr Val Val Thr Glu Ile Pro Lys Ser Gly 70 75 80 85 tgg atc atg ggc ggc ggc gag gtc tac aag gcc acc gtc ggc agc gcc 403 Trp Ile Met Gly Gly Gly Glu Val Tyr Lys Ala Thr Val Gly Ser Ala 90 95 100 gac gtt tta gaa ata acg ctt atc gac gcc acc ttc gat gtt tcc act 451 Asp Val Leu Glu Ile Thr Leu Ile Asp Ala Thr Phe Asp Val Ser Thr 105 110 115 ccc gtc tac gca ccc gaa atc ccg gcg aac ttc aac ctc gat gac gaa 499 Pro Val Tyr Ala Pro Glu Ile Pro Ala Asn Phe Asn Leu Asp Asp Glu 120 125 130 tcc gag tgg ttt acc tca ggc gag tat cgt tac aag ttc cag cgc tac 547 Ser Glu Trp Phe Thr Ser Gly Glu Tyr Arg Tyr Lys Phe Gln Arg Tyr 135 140 145 atc aag gtt taaggagcaa acaacatgag caa 579 Ile Lys Val 150 <210> 680 <211> 152 <212> PRT <213> Corynebacterium glutamicum <400> 680 Met Ile Gly Ala Ile Trp Ala Gln Gly Arg Asp Gly Ile Ile Gly Asp 1 5 10 15 Gly Thr Asp Met Pro Trp His Ile Pro Glu Asp Leu Lys His Phe Lys 20 25 30 Lys Thr Thr Met Gly Gln Pro Val Ile Met Gly Arg Arg Thr Trp Glu 35 40 45 Ser Leu Pro Phe Lys Pro Leu Pro Gly Arg Glu Asn Phe Ile Leu Ser 50 55 60 Ser Arg Glu Pro Gly Asp Trp Ser Ala Gly Gly Thr Val Val Thr Glu 65 70 75 80 Ile Pro Lys Ser Gly Trp Ile Met Gly Gly Gly Glu Val Tyr Lys Ala 85 90 95 Thr Val Gly Ser Ala Asp Val Leu Glu Ile Thr Leu Ile Asp Ala Thr 100 105 110 Phe Asp Val Ser Thr Pro Val Tyr Ala Pro Glu Ile Pro Ala Asn Phe 115 120 125 Asn Leu Asp Asp Glu Ser Glu Trp Phe Thr Ser Gly Glu Tyr Arg Tyr 130 135 140 Lys Phe Gln Arg Tyr Ile Lys Val 145 150 <210> 681 <211> 1044 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1021) <223> RXN01321 <400> 681 ggagggtgta gtcaaggatt tgggccatgg tggagcggga aatcgtcata tccataccct 60 acttagacct gacttagtgt gggaaaattt ccagggtaga atg caa cga atg acc 115 Met Gln Arg Met Thr 1 5 ccg agt tct cct gaa gtt cgt aat cgt ccg agc gct gcg cct gaa gag 163 Pro Ser Ser Pro Glu Val Arg Asn Arg Pro Ser Ala Ala Pro Glu Glu 10 15 20 cgt cag ttt gtg ctc act ttt ggc tgc cct gac tcc act gga att gtg 211 Arg Gln Phe Val Leu Thr Phe Gly Cys Pro Asp Ser Thr Gly Ile Val 25 30 35 gcg aag ttg tcg tcg ttc cta gct gag cgt ggg ggt tgg att act gag 259 Ala Lys Leu Ser Ser Phe Leu Ala Glu Arg Gly Gly Trp Ile Thr Glu 40 45 50 gct gga tat ttc acg gat cct gat tcg aat tgg ttc ttt act cgt cag 307 Ala Gly Tyr Phe Thr Asp Pro Asp Ser Asn Trp Phe Phe Thr Arg Gln 55 60 65 gcg att cgc gct gag tcg att gat acc acg att gag cag ttg cgg gag 355 Ala Ile Arg Ala Glu Ser Ile Asp Thr Thr Ile Glu Gln Leu Arg Glu 70 75 80 85 gag ttc gct ccg ctt gcg gag gag ttc ggc ccg agg gct aag tgg agt 403 Glu Phe Ala Pro Leu Ala Glu Glu Phe Gly Pro Arg Ala Lys Trp Ser 90 95 100 ttc act gac act gcg cag gtg aag aag gct gtg ttg ttg gtg tct aag 451 Phe Thr Asp Thr Ala Gln Val Lys Lys Ala Val Leu Leu Val Ser Lys 105 110 115 gag ggc cac tgc ttg cac gat ttg tta ggt cgt gtg gct gag aat gat 499 Glu Gly His Cys Leu His Asp Leu Leu Gly Arg Val Ala Glu Asn Asp 120 125 130 tat ccg atg gaa gtt gtt gcg gtt gtg ggt aac cat gag aac ttg cgt 547 Tyr Pro Met Glu Val Val Ala Val Val Gly Asn His Glu Asn Leu Arg 135 140 145 tat att gcg gag aac cat aat gtt ccg ttt ttc cat gtg ccg ttt cct 595 Tyr Ile Ala Glu Asn His Asn Val Pro Phe Phe His Val Pro Phe Pro 150 155 160 165 aag gat gcg gtt ggt aag cgg aag gcg ttt gac cag gtc gct gag att 643 Lys Asp Ala Val Gly Lys Arg Lys Ala Phe Asp Gln Val Ala Glu Ile 170 175 180 gtg aat ggt tat gat ccg gat gcg att gtt ttg gct cgt ttt atg cag 691 Val Asn Gly Tyr Asp Pro Asp Ala Ile Val Leu Ala Arg Phe Met Gln 185 190 195 att ttg ccg ccg gat ttg tgt gag atg tgg gct ggt cgt gtg ttg aat 739 Ile Leu Pro Pro Asp Leu Cys Glu Met Trp Ala Gly Arg Val Leu Asn 200 205 210 att cat cac agt ttc ttg ccg tcg ttt atg ggt gcg cgc ccg tat cat 787 Ile His His Ser Phe Leu Pro Ser Phe Met Gly Ala Arg Pro Tyr His 215 220 225 cag gcg tat agc cgt ggt gtg aag ttg att ggt gcg acc tgc cat tat 835 Gln Ala Tyr Ser Arg Gly Val Lys Leu Ile Gly Ala Thr Cys His Tyr 230 235 240 245 gcg act ggg gat ctg gat gat ggt ccg atc att gag cag gat gtt att 883 Ala Thr Gly Asp Leu Asp Asp Gly Pro Ile Ile Glu Gln Asp Val Ile 250 255 260 cgt gtg acg cat aag gat acg ccg act gag atg cag cgt ttg ggc cgc 931 Arg Val Thr His Lys Asp Thr Pro Thr Glu Met Gln Arg Leu Gly Arg 265 270 275 gat gcg gag aag cag gtg ctg gct cgc ggt ttg cgt ttc cac ttg gag 979 Asp Ala Glu Lys Gln Val Leu Ala Arg Gly Leu Arg Phe His Leu Glu 280 285 290 gac cgg gtg ctg gtt tac ggt aac cgc acg gtt gtc ttt gat 1021 Asp Arg Val Leu Val Tyr Gly Asn Arg Thr Val Val Phe Asp 295 300 305 taaggctttt tgcttttcga cgc 1044 <210> 682 <211> 307 <212> PRT <213> Corynebacterium glutamicum <400> 682 Met Gln Arg Met Thr Pro Ser Ser Pro Glu Val Arg Asn Arg Pro Ser 1 5 10 15 Ala Ala Pro Glu Glu Arg Gln Phe Val Leu Thr Phe Gly Cys Pro Asp 20 25 30 Ser Thr Gly Ile Val Ala Lys Leu Ser Ser Phe Leu Ala Glu Arg Gly 35 40 45 Gly Trp Ile Thr Glu Ala Gly Tyr Phe Thr Asp Pro Asp Ser Asn Trp 50 55 60 Phe Phe Thr Arg Gln Ala Ile Arg Ala Glu Ser Ile Asp Thr Thr Ile 65 70 75 80 Glu Gln Leu Arg Glu Glu Phe Ala Pro Leu Ala Glu Glu Phe Gly Pro 85 90 95 Arg Ala Lys Trp Ser Phe Thr Asp Thr Ala Gln Val Lys Lys Ala Val 100 105 110 Leu Leu Val Ser Lys Glu Gly His Cys Leu His Asp Leu Leu Gly Arg 115 120 125 Val Ala Glu Asn Asp Tyr Pro Met Glu Val Val Ala Val Val Gly Asn 130 135 140 His Glu Asn Leu Arg Tyr Ile Ala Glu Asn His Asn Val Pro Phe Phe 145 150 155 160 His Val Pro Phe Pro Lys Asp Ala Val Gly Lys Arg Lys Ala Phe Asp 165 170 175 Gln Val Ala Glu Ile Val Asn Gly Tyr Asp Pro Asp Ala Ile Val Leu 180 185 190 Ala Arg Phe Met Gln Ile Leu Pro Pro Asp Leu Cys Glu Met Trp Ala 195 200 205 Gly Arg Val Leu Asn Ile His His Ser Phe Leu Pro Ser Phe Met Gly 210 215 220 Ala Arg Pro Tyr His Gln Ala Tyr Ser Arg Gly Val Lys Leu Ile Gly 225 230 235 240 Ala Thr Cys His Tyr Ala Thr Gly Asp Leu Asp Asp Gly Pro Ile Ile 245 250 255 Glu Gln Asp Val Ile Arg Val Thr His Lys Asp Thr Pro Thr Glu Met 260 265 270 Gln Arg Leu Gly Arg Asp Ala Glu Lys Gln Val Leu Ala Arg Gly Leu 275 280 285 Arg Phe His Leu Glu Asp Arg Val Leu Val Tyr Gly Asn Arg Thr Val 290 295 300 Val Phe Asp 305 <210> 683 <211> 582 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (23)..(559) <223> FRXA01321 <400> 683 cttgcacgat ttgttaggtc gt gtg gct gag aat gat tat ccg atg gaa gtt 52 Val Ala Glu Asn Asp Tyr Pro Met Glu Val 1 5 10 gtt gcg gtt gtg ggt aac cat gag aac ttg cgt tat att gcg gag aac 100 Val Ala Val Val Gly Asn His Glu Asn Leu Arg Tyr Ile Ala Glu Asn 15 20 25 cat aat gtt ccg ttt ttc cat gtg ccg ttt cct aag gat gcg gtt ggt 148 His Asn Val Pro Phe Phe His Val Pro Phe Pro Lys Asp Ala Val Gly 30 35 40 aag cgg aag gcg ttt gac cag gtc gct gag att gtg aat ggt tat gat 196 Lys Arg Lys Ala Phe Asp Gln Val Ala Glu Ile Val Asn Gly Tyr Asp 45 50 55 ccg gat gcg att gtt ttg gct cgt ttt atg cag att ttg ccg ccg gat 244 Pro Asp Ala Ile Val Leu Ala Arg Phe Met Gln Ile Leu Pro Pro Asp 60 65 70 ttg tgt gag atg tgg gct ggt cgt gtg ttg aat att cat cac agt ttc 292 Leu Cys Glu Met Trp Ala Gly Arg Val Leu Asn Ile His His Ser Phe 75 80 85 90 ttg ccg tcg ttt atg ggt gcg cgc ccg tat cat cag gcg tat agc cgt 340 Leu Pro Ser Phe Met Gly Ala Arg Pro Tyr His Gln Ala Tyr Ser Arg 95 100 105 ggt gtg aag ttg att ggt gcg acc tgc cat tat gcg act ggg gat ctg 388 Gly Val Lys Leu Ile Gly Ala Thr Cys His Tyr Ala Thr Gly Asp Leu 110 115 120 gat gat ggt ccg atc att gag cag gat gtt att cgt gtg acg cat aag 436 Asp Asp Gly Pro Ile Ile Glu Gln Asp Val Ile Arg Val Thr His Lys 125 130 135 gat acg ccg act gag atg cag cgt ttg ggc cgc gat gcg gag aag cag 484 Asp Thr Pro Thr Glu Met Gln Arg Leu Gly Arg Asp Ala Glu Lys Gln 140 145 150 gtg ctg gct cgc ggt ttg cgt ttc cac ttg gag gac cgg gtg ctg gtt 532 Val Leu Ala Arg Gly Leu Arg Phe His Leu Glu Asp Arg Val Leu Val 155 160 165 170 tac ggt aac cgc acg gtt gtc ttt gat taaggctttt tgcttttcga 579 Tyr Gly Asn Arg Thr Val Val Phe Asp 175 cgc 582 <210> 684 <211> 179 <212> PRT <213> Corynebacterium glutamicum <400> 684 Val Ala Glu Asn Asp Tyr Pro Met Glu Val Val Ala Val Val Gly Asn 1 5 10 15 His Glu Asn Leu Arg Tyr Ile Ala Glu Asn His Asn Val Pro Phe Phe 20 25 30 His Val Pro Phe Pro Lys Asp Ala Val Gly Lys Arg Lys Ala Phe Asp 35 40 45 Gln Val Ala Glu Ile Val Asn Gly Tyr Asp Pro Asp Ala Ile Val Leu 50 55 60 Ala Arg Phe Met Gln Ile Leu Pro Pro Asp Leu Cys Glu Met Trp Ala 65 70 75 80 Gly Arg Val Leu Asn Ile His His Ser Phe Leu Pro Ser Phe Met Gly 85 90 95 Ala Arg Pro Tyr His Gln Ala Tyr Ser Arg Gly Val Lys Leu Ile Gly 100 105 110 Ala Thr Cys His Tyr Ala Thr Gly Asp Leu Asp Asp Gly Pro Ile Ile 115 120 125 Glu Gln Asp Val Ile Arg Val Thr His Lys Asp Thr Pro Thr Glu Met 130 135 140 Gln Arg Leu Gly Arg Asp Ala Glu Lys Gln Val Leu Ala Arg Gly Leu 145 150 155 160 Arg Phe His Leu Glu Asp Arg Val Leu Val Tyr Gly Asn Arg Thr Val 165 170 175 Val Phe Asp <210> 685 <211> 975 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(952) <223> RXA00461 <400> 685 tgttgggagg gatgacagga ttgtcgaaga taacgtgaag tgggtgttcc ggcatgtgtt 60 tgattgtaag gccttggaaa agggtggaat aatagcgggc gtg act gca atc aaa 115 Val Thr Ala Ile Lys 1 5 ctt gat gga aac tta tac cgc ggg gaa att ttc gcc gac ttg gaa cag 163 Leu Asp Gly Asn Leu Tyr Arg Gly Glu Ile Phe Ala Asp Leu Glu Gln 10 15 20 cgc gtt gct gcg ttg aag gag aaa ggg att gtg ccg ggg ctt gcc acc 211 Arg Val Ala Ala Leu Lys Glu Lys Gly Ile Val Pro Gly Leu Ala Thr 25 30 35 gtg ctg gtg ggt gat gac cca gcg agc cac tct tac gtg aag atg aag 259 Val Leu Val Gly Asp Asp Pro Ala Ser His Ser Tyr Val Lys Met Lys 40 45 50 cat cgt gac tgt gag cag att ggt gtg aac tcg atc cgt aag gat ctg 307 His Arg Asp Cys Glu Gln Ile Gly Val Asn Ser Ile Arg Lys Asp Leu 55 60 65 cct gct gat gtc acg cag gaa gag ctt ttc gct gtc atc gat gaa ctg 355 Pro Ala Asp Val Thr Gln Glu Glu Leu Phe Ala Val Ile Asp Glu Leu 70 75 80 85 aac aac gat gat tct tgc act ggt tac att gtg cag ctt cct ttg cct 403 Asn Asn Asp Asp Ser Cys Thr Gly Tyr Ile Val Gln Leu Pro Leu Pro 90 95 100 aag cac ttg gac gaa aac gct gtg ctg gag cgc att gat cca gct aag 451 Lys His Leu Asp Glu Asn Ala Val Leu Glu Arg Ile Asp Pro Ala Lys 105 110 115 gat gct gat ggc ctg cac cct gta aac ctg ggc aag ctt gtg ctc aac 499 Asp Ala Asp Gly Leu His Pro Val Asn Leu Gly Lys Leu Val Leu Asn 120 125 130 gag cca gct cca ctg cca tgc acc ccg aat ggt tcc atc agc ttg ttg 547 Glu Pro Ala Pro Leu Pro Cys Thr Pro Asn Gly Ser Ile Ser Leu Leu 135 140 145 cgt cgt ttc ggc gtt gag ctt gat ggc gcg aag gtt gtt gtc att ggc 595 Arg Arg Phe Gly Val Glu Leu Asp Gly Ala Lys Val Val Val Ile Gly 150 155 160 165 cgt ggc gtc acc gtt ggt cgc cca att ggc ctg atg ctg acc cgc cgt 643 Arg Gly Val Thr Val Gly Arg Pro Ile Gly Leu Met Leu Thr Arg Arg 170 175 180 tcc gag aac tcc acg gtt act ttg tgc cac act ggc acg aag gat ctg 691 Ser Glu Asn Ser Thr Val Thr Leu Cys His Thr Gly Thr Lys Asp Leu 185 190 195 gct gcg gag acc cgt gcg gct gac gtc atc att gct gca gct ggt cag 739 Ala Ala Glu Thr Arg Ala Ala Asp Val Ile Ile Ala Ala Ala Gly Gln 200 205 210 ccg cac atg ctg acc gca gac atg gtc aag cca ggc gca gcg gtg ctc 787 Pro His Met Leu Thr Ala Asp Met Val Lys Pro Gly Ala Ala Val Leu 215 220 225 gat gtc ggc gtc tcc cgc aag gac ggc aag ttg ctt ggc gac gtc cac 835 Asp Val Gly Val Ser Arg Lys Asp Gly Lys Leu Leu Gly Asp Val His 230 235 240 245 ccc gac gtg tgg gaa gtc gcc ggc gcg gtc tca cca aac cca ggc ggc 883 Pro Asp Val Trp Glu Val Ala Gly Ala Val Ser Pro Asn Pro Gly Gly 250 255 260 gtt ggc cct ctg acc cgt gca ttc ttg gtg cac aat gtt gtc gag cgc 931 Val Gly Pro Leu Thr Arg Ala Phe Leu Val His Asn Val Val Glu Arg 265 270 275 gct gaa aag ctg gct gga ctc taaaaacaca tgactaatcc cgg 975 Ala Glu Lys Leu Ala Gly Leu 280 <210> 686 <211> 284 <212> PRT <213> Corynebacterium glutamicum <400> 686 Val Thr Ala Ile Lys Leu Asp Gly Asn Leu Tyr Arg Gly Glu Ile Phe 1 5 10 15 Ala Asp Leu Glu Gln Arg Val Ala Ala Leu Lys Glu Lys Gly Ile Val 20 25 30 Pro Gly Leu Ala Thr Val Leu Val Gly Asp Asp Pro Ala Ser His Ser 35 40 45 Tyr Val Lys Met Lys His Arg Asp Cys Glu Gln Ile Gly Val Asn Ser 50 55 60 Ile Arg Lys Asp Leu Pro Ala Asp Val Thr Gln Glu Glu Leu Phe Ala 65 70 75 80 Val Ile Asp Glu Leu Asn Asn Asp Asp Ser Cys Thr Gly Tyr Ile Val 85 90 95 Gln Leu Pro Leu Pro Lys His Leu Asp Glu Asn Ala Val Leu Glu Arg 100 105 110 Ile Asp Pro Ala Lys Asp Ala Asp Gly Leu His Pro Val Asn Leu Gly 115 120 125 Lys Leu Val Leu Asn Glu Pro Ala Pro Leu Pro Cys Thr Pro Asn Gly 130 135 140 Ser Ile Ser Leu Leu Arg Arg Phe Gly Val Glu Leu Asp Gly Ala Lys 145 150 155 160 Val Val Val Ile Gly Arg Gly Val Thr Val Gly Arg Pro Ile Gly Leu 165 170 175 Met Leu Thr Arg Arg Ser Glu Asn Ser Thr Val Thr Leu Cys His Thr 180 185 190 Gly Thr Lys Asp Leu Ala Ala Glu Thr Arg Ala Ala Asp Val Ile Ile 195 200 205 Ala Ala Ala Gly Gln Pro His Met Leu Thr Ala Asp Met Val Lys Pro 210 215 220 Gly Ala Ala Val Leu Asp Val Gly Val Ser Arg Lys Asp Gly Lys Leu 225 230 235 240 Leu Gly Asp Val His Pro Asp Val Trp Glu Val Ala Gly Ala Val Ser 245 250 255 Pro Asn Pro Gly Gly Val Gly Pro Leu Thr Arg Ala Phe Leu Val His 260 265 270 Asn Val Val Glu Arg Ala Glu Lys Leu Ala Gly Leu 275 280 <210> 687 <211> 711 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(688) <223> RXA01514 <400> 687 accacagaaa tgcctgtcgt tccagatcag cccatcgatg gtgattccgg gaagtccgct 60 gagggcacac aggagaatcc ggaaaatgaa ggagacaacc gtg gat aac cac gct 115 Val Asp Asn His Ala 1 5 gca gtt cgc gag ttc gat gag gag cgc gca aca gct gcg att cgt gag 163 Ala Val Arg Glu Phe Asp Glu Glu Arg Ala Thr Ala Ala Ile Arg Glu 10 15 20 ttg ctc atc gct gtg ggt gag gat cca gat cgc gaa ggc ctg ttg gaa 211 Leu Leu Ile Ala Val Gly Glu Asp Pro Asp Arg Glu Gly Leu Leu Glu 25 30 35 acc cca gct cga gtg gct agg gcg tac aag gaa act ttc gcg ggt ctg 259 Thr Pro Ala Arg Val Ala Arg Ala Tyr Lys Glu Thr Phe Ala Gly Leu 40 45 50 cat gag gat ccc acc act gtg ctg gag aag acg ttc tct gag ggc cat 307 His Glu Asp Pro Thr Thr Val Leu Glu Lys Thr Phe Ser Glu Gly His 55 60 65 gaa gag ttg gtt ctg gtt cgt gag atc ccg att tac tcc atg tgt gag 355 Glu Glu Leu Val Leu Val Arg Glu Ile Pro Ile Tyr Ser Met Cys Glu 70 75 80 85 cac cac ttg gtg ccg ttc ttt ggc gtg gcg cac att ggt tac att ccg 403 His His Leu Val Pro Phe Phe Gly Val Ala His Ile Gly Tyr Ile Pro 90 95 100 ggt aag tcc ggc aag gtg act ggc ctg tcc aag ctg gcg cgt tta gcg 451 Gly Lys Ser Gly Lys Val Thr Gly Leu Ser Lys Leu Ala Arg Leu Ala 105 110 115 gat atg ttt gct aag cga cct cag gtt cag gag cgc ttg acc tcc caa 499 Asp Met Phe Ala Lys Arg Pro Gln Val Gln Glu Arg Leu Thr Ser Gln 120 125 130 att gcg gat gct ctc gtc gaa aag ctt gat gcc cag gcc gtg gcc gtg 547 Ile Ala Asp Ala Leu Val Glu Lys Leu Asp Ala Gln Ala Val Ala Val 135 140 145 gtg att gaa gct gag cac ctg tgc atg gcc atg cgc gga atc cgt aag 595 Val Ile Glu Ala Glu His Leu Cys Met Ala Met Arg Gly Ile Arg Lys 150 155 160 165 cct ggt gct gtg acc acg acg tct gcg gtg cgc ggc ggt ttt aag aac 643 Pro Gly Ala Val Thr Thr Thr Ser Ala Val Arg Gly Gly Phe Lys Asn 170 175 180 aac gct gcc tcc cgc gct gag gtg ttc tcc ctg att cgg ggg cac 688 Asn Ala Ala Ser Arg Ala Glu Val Phe Ser Leu Ile Arg Gly His 185 190 195 taaatgaacg tatcctcttt gac 711 <210> 688 <211> 196 <212> PRT <213> Corynebacterium glutamicum <400> 688 Val Asp Asn His Ala Ala Val Arg Glu Phe Asp Glu Glu Arg Ala Thr 1 5 10 15 Ala Ala Ile Arg Glu Leu Leu Ile Ala Val Gly Glu Asp Pro Asp Arg 20 25 30 Glu Gly Leu Leu Glu Thr Pro Ala Arg Val Ala Arg Ala Tyr Lys Glu 35 40 45 Thr Phe Ala Gly Leu His Glu Asp Pro Thr Thr Val Leu Glu Lys Thr 50 55 60 Phe Ser Glu Gly His Glu Glu Leu Val Leu Val Arg Glu Ile Pro Ile 65 70 75 80 Tyr Ser Met Cys Glu His His Leu Val Pro Phe Phe Gly Val Ala His 85 90 95 Ile Gly Tyr Ile Pro Gly Lys Ser Gly Lys Val Thr Gly Leu Ser Lys 100 105 110 Leu Ala Arg Leu Ala Asp Met Phe Ala Lys Arg Pro Gln Val Gln Glu 115 120 125 Arg Leu Thr Ser Gln Ile Ala Asp Ala Leu Val Glu Lys Leu Asp Ala 130 135 140 Gln Ala Val Ala Val Val Ile Glu Ala Glu His Leu Cys Met Ala Met 145 150 155 160 Arg Gly Ile Arg Lys Pro Gly Ala Val Thr Thr Thr Ser Ala Val Arg 165 170 175 Gly Gly Phe Lys Asn Asn Ala Ala Ser Arg Ala Glu Val Phe Ser Leu 180 185 190 Ile Arg Gly His 195 <210> 689 <211> 513 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(490) <223> RXA01516 <400> 689 tctgcacata tgggagcatg gggtgtgcgc gtgcacgatg tcccagtatc aagggacgct 60 gttgatgttg ccgcattgtg gcgaagtgga ggaactcacc atg gct gat cgt att 115 Met Ala Asp Arg Ile 1 5 gaa ctt aaa ggc ctt gaa tgc ttc gga cac cac ggt gtg ttc gac ttt 163 Glu Leu Lys Gly Leu Glu Cys Phe Gly His His Gly Val Phe Asp Phe 10 15 20 gaa aaa gag caa ggc cag ccc ttc att gtg gat gtc acc tgc tgg atg 211 Glu Lys Glu Gln Gly Gln Pro Phe Ile Val Asp Val Thr Cys Trp Met 25 30 35 gat ttc gat gcc gca ggt gcc agc gat gac ctt tcc gac acc gta gat 259 Asp Phe Asp Ala Ala Gly Ala Ser Asp Asp Leu Ser Asp Thr Val Asp 40 45 50 tac ggc gcg ttg gca ttg ttg gtt gct gaa atc gtg gaa ggc cca tcc 307 Tyr Gly Ala Leu Ala Leu Leu Val Ala Glu Ile Val Glu Gly Pro Ser 55 60 65 agg gat ttg atc gag acg gtg gcc acg gaa tct gcg gat gct gtg atg 355 Arg Asp Leu Ile Glu Thr Val Ala Thr Glu Ser Ala Asp Ala Val Met 70 75 80 85 gct aaa ttt gat gcg ctt cat gcg gtg gaa gta acc atc cat aag ccc 403 Ala Lys Phe Asp Ala Leu His Ala Val Glu Val Thr Ile His Lys Pro 90 95 100 aaa gca ccg atc cca cgt act ttt gct gac gtc gcg gtg gtt gcc cga 451 Lys Ala Pro Ile Pro Arg Thr Phe Ala Asp Val Ala Val Val Ala Arg 105 110 115 cgt tcc agg aaa tcc atg gct gct gga agg agc aac gcc taatgcatgc 500 Arg Ser Arg Lys Ser Met Ala Ala Gly Arg Ser Asn Ala 120 125 130 agttttgtcc atc 513 <210> 690 <211> 130 <212> PRT <213> Corynebacterium glutamicum <400> 690 Met Ala Asp Arg Ile Glu Leu Lys Gly Leu Glu Cys Phe Gly His His 1 5 10 15 Gly Val Phe Asp Phe Glu Lys Glu Gln Gly Gln Pro Phe Ile Val Asp 20 25 30 Val Thr Cys Trp Met Asp Phe Asp Ala Ala Gly Ala Ser Asp Asp Leu 35 40 45 Ser Asp Thr Val Asp Tyr Gly Ala Leu Ala Leu Leu Val Ala Glu Ile 50 55 60 Val Glu Gly Pro Ser Arg Asp Leu Ile Glu Thr Val Ala Thr Glu Ser 65 70 75 80 Ala Asp Ala Val Met Ala Lys Phe Asp Ala Leu His Ala Val Glu Val 85 90 95 Thr Ile His Lys Pro Lys Ala Pro Ile Pro Arg Thr Phe Ala Asp Val 100 105 110 Ala Val Val Ala Arg Arg Ser Arg Lys Ser Met Ala Ala Gly Arg Ser 115 120 125 Asn Ala 130 <210> 691 <211> 975 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(952) <223> RXA01515 <400> 691 taagcctggt gctgtgacca cgacgtctgc ggtgcgcggc ggttttaaga acaacgctgc 60 ctcccgcgct gaggtgttct ccctgattcg ggggcactaa atg aac gta tcc tct 115 Met Asn Val Ser Ser 1 5 ttg acc atc ccg gga cgc tgt ttg gtc atg gga att gtc aat gtc act 163 Leu Thr Ile Pro Gly Arg Cys Leu Val Met Gly Ile Val Asn Val Thr 10 15 20 gag gat tcc ttt tcg gac ggt ggc aag tac att gac gtt gat cag gcg 211 Glu Asp Ser Phe Ser Asp Gly Gly Lys Tyr Ile Asp Val Asp Gln Ala 25 30 35 atc gcg cat gcc aag gaa ttg gtg gct gct ggc gcc gac atg att gat 259 Ile Ala His Ala Lys Glu Leu Val Ala Ala Gly Ala Asp Met Ile Asp 40 45 50 gtc ggc ggc gag tcc acc cgg cct ggg gca gtg cgc gtc gac gcg tcc 307 Val Gly Gly Glu Ser Thr Arg Pro Gly Ala Val Arg Val Asp Ala Ser 55 60 65 gtg gaa cgg gac cgg gtt gtg ccg gtc att aag gcg ctt cac gac gcc 355 Val Glu Arg Asp Arg Val Val Pro Val Ile Lys Ala Leu His Asp Ala 70 75 80 85 ggc atc cac act tcc gta gac acc atg cgg gcc tcc gtg gcg cag gct 403 Gly Ile His Thr Ser Val Asp Thr Met Arg Ala Ser Val Ala Gln Ala 90 95 100 gcc gcg ggc gct ggc gtc tcc atg atc aac gac gtc tct ggc ggt ttg 451 Ala Ala Gly Ala Gly Val Ser Met Ile Asn Asp Val Ser Gly Gly Leu 105 110 115 gct gat cct gag atg ttt tct gtc atg gcg gaa gcg caa att ccc gtg 499 Ala Asp Pro Glu Met Phe Ser Val Met Ala Glu Ala Gln Ile Pro Val 120 125 130 tgt ttg atg cac tgg cgc acc ctc caa ttc ggt gat gcc gca ggt cag 547 Cys Leu Met His Trp Arg Thr Leu Gln Phe Gly Asp Ala Ala Gly Gln 135 140 145 gca gat cac ggt gga gac gtt gta gcc gat gtg cac gca gtg ctt gat 595 Ala Asp His Gly Gly Asp Val Val Ala Asp Val His Ala Val Leu Asp 150 155 160 165 gat ctt gtc gcc cgc gcc acc gct gct ggt gtg gcc gaa aac cag atc 643 Asp Leu Val Ala Arg Ala Thr Ala Ala Gly Val Ala Glu Asn Gln Ile 170 175 180 gtg ctt gat cca ggt ttg ggt ttt gcc aaa tca cgt gaa gac aac tgg 691 Val Leu Asp Pro Gly Leu Gly Phe Ala Lys Ser Arg Glu Asp Asn Trp 185 190 195 cgt ttg ctg caa gca ctg ccc gag ttt att tct gga cct ttc ccc atc 739 Arg Leu Leu Gln Ala Leu Pro Glu Phe Ile Ser Gly Pro Phe Pro Ile 200 205 210 ctg gtg gga gca tcc cgg aag cga ttc ctg gct ggc gtg cgc aaa gac 787 Leu Val Gly Ala Ser Arg Lys Arg Phe Leu Ala Gly Val Arg Lys Asp 215 220 225 cgt ggc cta gat gtc acc ccc att gat gcc gac cca gca acc gca gcg 835 Arg Gly Leu Asp Val Thr Pro Ile Asp Ala Asp Pro Ala Thr Ala Ala 230 235 240 245 gtg acc gca gtg tct gca cat atg gga gca tgg ggt gtg cgc gtg cac 883 Val Thr Ala Val Ser Ala His Met Gly Ala Trp Gly Val Arg Val His 250 255 260 gat gtc cca gta tca agg gac gct gtt gat gtt gcc gca ttg tgg cga 931 Asp Val Pro Val Ser Arg Asp Ala Val Asp Val Ala Ala Leu Trp Arg 265 270 275 agt gga gga act cac cat ggc tgatcgtatt gaacttaaag gcc 975 Ser Gly Gly Thr His His Gly 280 <210> 692 <211> 284 <212> PRT <213> Corynebacterium glutamicum <400> 692 Met Asn Val Ser Ser Leu Thr Ile Pro Gly Arg Cys Leu Val Met Gly 1 5 10 15 Ile Val Asn Val Thr Glu Asp Ser Phe Ser Asp Gly Gly Lys Tyr Ile 20 25 30 Asp Val Asp Gln Ala Ile Ala His Ala Lys Glu Leu Val Ala Ala Gly 35 40 45 Ala Asp Met Ile Asp Val Gly Gly Glu Ser Thr Arg Pro Gly Ala Val 50 55 60 Arg Val Asp Ala Ser Val Glu Arg Asp Arg Val Val Pro Val Ile Lys 65 70 75 80 Ala Leu His Asp Ala Gly Ile His Thr Ser Val Asp Thr Met Arg Ala 85 90 95 Ser Val Ala Gln Ala Ala Ala Gly Ala Gly Val Ser Met Ile Asn Asp 100 105 110 Val Ser Gly Gly Leu Ala Asp Pro Glu Met Phe Ser Val Met Ala Glu 115 120 125 Ala Gln Ile Pro Val Cys Leu Met His Trp Arg Thr Leu Gln Phe Gly 130 135 140 Asp Ala Ala Gly Gln Ala Asp His Gly Gly Asp Val Val Ala Asp Val 145 150 155 160 His Ala Val Leu Asp Asp Leu Val Ala Arg Ala Thr Ala Ala Gly Val 165 170 175 Ala Glu Asn Gln Ile Val Leu Asp Pro Gly Leu Gly Phe Ala Lys Ser 180 185 190 Arg Glu Asp Asn Trp Arg Leu Leu Gln Ala Leu Pro Glu Phe Ile Ser 195 200 205 Gly Pro Phe Pro Ile Leu Val Gly Ala Ser Arg Lys Arg Phe Leu Ala 210 215 220 Gly Val Arg Lys Asp Arg Gly Leu Asp Val Thr Pro Ile Asp Ala Asp 225 230 235 240 Pro Ala Thr Ala Ala Val Thr Ala Val Ser Ala His Met Gly Ala Trp 245 250 255 Gly Val Arg Val His Asp Val Pro Val Ser Arg Asp Ala Val Asp Val 260 265 270 Ala Ala Leu Trp Arg Ser Gly Gly Thr His His Gly 275 280 <210> 693 <211> 859 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(859) <223> RXA02024 <400> 693 cactgatgac ctggatcagg ccgtcaaatt catcgtcgat gcacacgctg gattggacgt 60 agcgcgtctc cacaattaag cagtggctac attaggtgtt atg agt tct ttg ccg 115 Met Ser Ser Leu Pro 1 5 gtc atc atg gcc atc gtc aat cgc acc ccg gat tct ttc tat gac aag 163 Val Ile Met Ala Ile Val Asn Arg Thr Pro Asp Ser Phe Tyr Asp Lys 10 15 20 ggt gcg aca ttt gag gac acc gct gcg cta aac agg gca gcg gag gtc 211 Gly Ala Thr Phe Glu Asp Thr Ala Ala Leu Asn Arg Ala Ala Glu Val 25 30 35 att gaa caa ggc gcc ggc att gtc gat atc ggt ggg gtg aaa gcc ggc 259 Ile Glu Gln Gly Ala Gly Ile Val Asp Ile Gly Gly Val Lys Ala Gly 40 45 50 ccg ggg gat ttc gtg tcg gcg gag gaa gag atc gac cgc gtg gtg cca 307 Pro Gly Asp Phe Val Ser Ala Glu Glu Glu Ile Asp Arg Val Val Pro 55 60 65 atc atc gct gcg gtg cga gaa cgt ttt cct gac att gat att tct gtt 355 Ile Ile Ala Ala Val Arg Glu Arg Phe Pro Asp Ile Asp Ile Ser Val 70 75 80 85 gat acc tgg cgg gcg tcg gtg gct gat gtc gca gtg gcg cat gga gca 403 Asp Thr Trp Arg Ala Ser Val Ala Asp Val Ala Val Ala His Gly Ala 90 95 100 acg ctg atc aat gac act tgg gcc ggc cat gat cat gag ttg gtg cag 451 Thr Leu Ile Asn Asp Thr Trp Ala Gly His Asp His Glu Leu Val Gln 105 110 115 gta gca ggg cag cac aag gtg ggt tat gtc tgc tcg cac acc ggc ggg 499 Val Ala Gly Gln His Lys Val Gly Tyr Val Cys Ser His Thr Gly Gly 120 125 130 gtg att cca aga acg cga cca tat cgg gtg cat ttc gat gac atc gtg 547 Val Ile Pro Arg Thr Arg Pro Tyr Arg Val His Phe Asp Asp Ile Val 135 140 145 gcc gat gta att acg gag acc acc aaa ttg gca gag caa gct gtt cgt 595 Ala Asp Val Ile Thr Glu Thr Thr Lys Leu Ala Glu Gln Ala Val Arg 150 155 160 165 gcc ggg gtg cca gag gaa cgg gtg ttt att gat ccc acc cat gat ttc 643 Ala Gly Val Pro Glu Glu Arg Val Phe Ile Asp Pro Thr His Asp Phe 170 175 180 ggg aaa aac acc ttc cac gga ctg gag ctt tta cga cgg atc gat gag 691 Gly Lys Asn Thr Phe His Gly Leu Glu Leu Leu Arg Arg Ile Asp Glu 185 190 195 gtg gtt gcc acg ggc tgg ccg gtg ctg atg gcc ttg agt aat aag gat 739 Val Val Ala Thr Gly Trp Pro Val Leu Met Ala Leu Ser Asn Lys Asp 200 205 210 ttc att ggg gaa act ttg gaa agg ggc gtc gat aag cgt gtt gct ggc 787 Phe Ile Gly Glu Thr Leu Glu Arg Gly Val Asp Lys Arg Val Ala Gly 215 220 225 acg ctt gct gcc act gcc tgg gcg gcg gcg cgc ggc gtt gcg gct ttt 835 Thr Leu Ala Ala Thr Ala Trp Ala Ala Ala Arg Gly Val Ala Ala Phe 230 235 240 245 cgc gtg cat gaa gtt gcg gaa acc 859 Arg Val His Glu Val Ala Glu Thr 250 <210> 694 <211> 253 <212> PRT <213> Corynebacterium glutamicum <400> 694 Met Ser Ser Leu Pro Val Ile Met Ala Ile Val Asn Arg Thr Pro Asp 1 5 10 15 Ser Phe Tyr Asp Lys Gly Ala Thr Phe Glu Asp Thr Ala Ala Leu Asn 20 25 30 Arg Ala Ala Glu Val Ile Glu Gln Gly Ala Gly Ile Val Asp Ile Gly 35 40 45 Gly Val Lys Ala Gly Pro Gly Asp Phe Val Ser Ala Glu Glu Glu Ile 50 55 60 Asp Arg Val Val Pro Ile Ile Ala Ala Val Arg Glu Arg Phe Pro Asp 65 70 75 80 Ile Asp Ile Ser Val Asp Thr Trp Arg Ala Ser Val Ala Asp Val Ala 85 90 95 Val Ala His Gly Ala Thr Leu Ile Asn Asp Thr Trp Ala Gly His Asp 100 105 110 His Glu Leu Val Gln Val Ala Gly Gln His Lys Val Gly Tyr Val Cys 115 120 125 Ser His Thr Gly Gly Val Ile Pro Arg Thr Arg Pro Tyr Arg Val His 130 135 140 Phe Asp Asp Ile Val Ala Asp Val Ile Thr Glu Thr Thr Lys Leu Ala 145 150 155 160 Glu Gln Ala Val Arg Ala Gly Val Pro Glu Glu Arg Val Phe Ile Asp 165 170 175 Pro Thr His Asp Phe Gly Lys Asn Thr Phe His Gly Leu Glu Leu Leu 180 185 190 Arg Arg Ile Asp Glu Val Val Ala Thr Gly Trp Pro Val Leu Met Ala 195 200 205 Leu Ser Asn Lys Asp Phe Ile Gly Glu Thr Leu Glu Arg Gly Val Asp 210 215 220 Lys Arg Val Ala Gly Thr Leu Ala Ala Thr Ala Trp Ala Ala Ala Arg 225 230 235 240 Gly Val Ala Ala Phe Arg Val His Glu Val Ala Glu Thr 245 250 <210> 695 <211> 579 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(556) <223> RXA00106 <400> 695 tggagctcaa caaggcagcg tacatgtttg agtacagctt cgatgacatc accgtgtccg 60 gctacgatcc acacccattg atccgcggca aggtcgccgt atg atc ggt gcg att 115 Met Ile Gly Ala Ile 1 5 tgg gca caa ggc cgt gac ggc atc atc ggc gac ggc acc gac atg ccc 163 Trp Ala Gln Gly Arg Asp Gly Ile Ile Gly Asp Gly Thr Asp Met Pro 10 15 20 tgg cac atc ccg gaa gac ctc aaa cac ttc aag aaa acc acc atg ggc 211 Trp His Ile Pro Glu Asp Leu Lys His Phe Lys Lys Thr Thr Met Gly 25 30 35 cag ccg gtc atc atg ggt cgt cgc acg tgg gag tct ttg ccg ttc aag 259 Gln Pro Val Ile Met Gly Arg Arg Thr Trp Glu Ser Leu Pro Phe Lys 40 45 50 ccg ctt ccc ggc cgc gag aac ttc att ctc tcc tca cgc gag ccc ggc 307 Pro Leu Pro Gly Arg Glu Asn Phe Ile Leu Ser Ser Arg Glu Pro Gly 55 60 65 gac tgg tcc gcc ggc ggc aca gtg gtc acc gaa atc cct aaa agc ggc 355 Asp Trp Ser Ala Gly Gly Thr Val Val Thr Glu Ile Pro Lys Ser Gly 70 75 80 85 tgg atc atg ggc ggc ggc gag gtc tac aag gcc acc gtc ggc agc gcc 403 Trp Ile Met Gly Gly Gly Glu Val Tyr Lys Ala Thr Val Gly Ser Ala 90 95 100 gac gtt tta gaa ata acg ctt atc gac gcc acc ttc gat gtt tcc act 451 Asp Val Leu Glu Ile Thr Leu Ile Asp Ala Thr Phe Asp Val Ser Thr 105 110 115 ccc gtc tac gca ccc gaa atc ccg gcg aac ttc aac ctc gat gac gaa 499 Pro Val Tyr Ala Pro Glu Ile Pro Ala Asn Phe Asn Leu Asp Asp Glu 120 125 130 tcc gag tgg ttt acc tca ggc gag tat cgt tac aag ttc cag cgc tac 547 Ser Glu Trp Phe Thr Ser Gly Glu Tyr Arg Tyr Lys Phe Gln Arg Tyr 135 140 145 atc aag gtt taaggagcaa acaacatgag caa 579 Ile Lys Val 150 <210> 696 <211> 152 <212> PRT <213> Corynebacterium glutamicum <400> 696 Met Ile Gly Ala Ile Trp Ala Gln Gly Arg Asp Gly Ile Ile Gly Asp 1 5 10 15 Gly Thr Asp Met Pro Trp His Ile Pro Glu Asp Leu Lys His Phe Lys 20 25 30 Lys Thr Thr Met Gly Gln Pro Val Ile Met Gly Arg Arg Thr Trp Glu 35 40 45 Ser Leu Pro Phe Lys Pro Leu Pro Gly Arg Glu Asn Phe Ile Leu Ser 50 55 60 Ser Arg Glu Pro Gly Asp Trp Ser Ala Gly Gly Thr Val Val Thr Glu 65 70 75 80 Ile Pro Lys Ser Gly Trp Ile Met Gly Gly Gly Glu Val Tyr Lys Ala 85 90 95 Thr Val Gly Ser Ala Asp Val Leu Glu Ile Thr Leu Ile Asp Ala Thr 100 105 110 Phe Asp Val Ser Thr Pro Val Tyr Ala Pro Glu Ile Pro Ala Asn Phe 115 120 125 Asn Leu Asp Asp Glu Ser Glu Trp Phe Thr Ser Gly Glu Tyr Arg Tyr 130 135 140 Lys Phe Gln Arg Tyr Ile Lys Val 145 150 <210> 697 <211> 1556 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1533) <223> RXA00989 <400> 697 gga att ggc cta gtg gct aac aac gac gga atc ttt gat tcc gaa aat 48 Gly Ile Gly Leu Val Ala Asn Asn Asp Gly Ile Phe Asp Ser Glu Asn 1 5 10 15 gat gac atc acc gta ggc gat gtc acg ttg ggc gag act gga ctg tct 96 Asp Asp Ile Thr Val Gly Asp Val Thr Leu Gly Glu Thr Gly Leu Ser 20 25 30 ttg ccc atc gat ctc gcc ggt gag gta gaa gca cct gcc tcc gag gag 144 Leu Pro Ile Asp Leu Ala Gly Glu Val Glu Ala Pro Ala Ser Glu Glu 35 40 45 atc acc caa gaa gat ttg ctg cgc ctt gcc cag gtg gaa gca gag ttg 192 Ile Thr Gln Glu Asp Leu Leu Arg Leu Ala Gln Val Glu Ala Glu Leu 50 55 60 gat caa cgt tgg ttg gaa acc aaa att gat ccc act ttc cga cgc atg 240 Asp Gln Arg Trp Leu Glu Thr Lys Ile Asp Pro Thr Phe Arg Arg Met 65 70 75 80 agc tac atg atg gat ctc atg ggc caa cca cag aat tcc ttc cca gca 288 Ser Tyr Met Met Asp Leu Met Gly Gln Pro Gln Asn Ser Phe Pro Ala 85 90 95 att cac gtg gct ggc acc aac ggt aag acc tcc acc acc cgc atg atc 336 Ile His Val Ala Gly Thr Asn Gly Lys Thr Ser Thr Thr Arg Met Ile 100 105 110 gag tcg ttg ctg cgc gca ttc cac cgc cgc acc ggc cgg acc acc agc 384 Glu Ser Leu Leu Arg Ala Phe His Arg Arg Thr Gly Arg Thr Thr Ser 115 120 125 ccg cac ctg cag ctg gta acc gaa cgc atc gcg att gat ggc aag ccc 432 Pro His Leu Gln Leu Val Thr Glu Arg Ile Ala Ile Asp Gly Lys Pro 130 135 140 atc cac ccg cgt gat ttc gtg cgg atc tac gaa gag att aag ccc tac 480 Ile His Pro Arg Asp Phe Val Arg Ile Tyr Glu Glu Ile Lys Pro Tyr 145 150 155 160 atg gag atg acc gac gcc tgg tca gag gcc gag ggc gga ccg aag atg 528 Met Glu Met Thr Asp Ala Trp Ser Glu Ala Glu Gly Gly Pro Lys Met 165 170 175 agc aag ttt gag gca ctc gtg gcc ctc gct tac gca ggt ttt gcc gac 576 Ser Lys Phe Glu Ala Leu Val Ala Leu Ala Tyr Ala Gly Phe Ala Asp 180 185 190 gct cct gtt gac gtc gcc gtc gtt gag gtt ggt ctt ggc gga cgc tgg 624 Ala Pro Val Asp Val Ala Val Val Glu Val Gly Leu Gly Gly Arg Trp 195 200 205 gat gcc act aac gtg atc aac gca gct gtt tcc gtg atc acc ccg gtg 672 Asp Ala Thr Asn Val Ile Asn Ala Ala Val Ser Val Ile Thr Pro Val 210 215 220 ggc atg gac cac gtg gat cgc ctg ggc aac acc att ggt gaa atc gct 720 Gly Met Asp His Val Asp Arg Leu Gly Asn Thr Ile Gly Glu Ile Ala 225 230 235 240 ggt gaa aag gcc ggc atc atc aag gct cgt cct gca tct gag gat ggc 768 Gly Glu Lys Ala Gly Ile Ile Lys Ala Arg Pro Ala Ser Glu Asp Gly 245 250 255 acc gag cct gag ggc aac gtt gtc atc gtg ggc aag cag gag cca gaa 816 Thr Glu Pro Glu Gly Asn Val Val Ile Val Gly Lys Gln Glu Pro Glu 260 265 270 gca atg aac gtg att ctg cag caa gcc gtg gac gtg gac gca gct gtt 864 Ala Met Asn Val Ile Leu Gln Gln Ala Val Asp Val Asp Ala Ala Val 275 280 285 gct cgt ttg aac atg gaa ttc ggc gtg gtg gaa tcc gcc att gcc gtt 912 Ala Arg Leu Asn Met Glu Phe Gly Val Val Glu Ser Ala Ile Ala Val 290 295 300 ggt gga cag cag ctc acc ctg aag ggt ttg ggc ggc gaa tac acc gac 960 Gly Gly Gln Gln Leu Thr Leu Lys Gly Leu Gly Gly Glu Tyr Thr Asp 305 310 315 320 atc ttc ctc cca ctg tct ggc gcg cac caa gca gat aat gcc gcg gtt 1008 Ile Phe Leu Pro Leu Ser Gly Ala His Gln Ala Asp Asn Ala Ala Val 325 330 335 gct ctc gca gca gtg gaa gca ttt ttc ggt gca tcc gcc gga cgc cca 1056 Ala Leu Ala Ala Val Glu Ala Phe Phe Gly Ala Ser Ala Gly Arg Pro 340 345 350 ttg gat atc gac acg gtg cgc gaa ggc ttc gca caa gtt cag tcc cca 1104 Leu Asp Ile Asp Thr Val Arg Glu Gly Phe Ala Gln Val Gln Ser Pro 355 360 365 ggt cgc ctc gag cgc ctg cgc tct gca cca acc gtg ttc atc gac gca 1152 Gly Arg Leu Glu Arg Leu Arg Ser Ala Pro Thr Val Phe Ile Asp Ala 370 375 380 gct cac aac cca cac ggt gcc gca gca ctt ggt gca gca cta gac cgt 1200 Ala His Asn Pro His Gly Ala Ala Ala Leu Gly Ala Ala Leu Asp Arg 385 390 395 400 gac ttt gag ttc cgt cgc ctc atc ggt gtc atc gga gtg ctc tgc gac 1248 Asp Phe Glu Phe Arg Arg Leu Ile Gly Val Ile Gly Val Leu Cys Asp 405 410 415 aag gat gcc cgc ggc atc ttg gaa tca ctt gag cca tac ctg cat gaa 1296 Lys Asp Ala Arg Gly Ile Leu Glu Ser Leu Glu Pro Tyr Leu His Glu 420 425 430 att gtg tgc acc cag act gcc tca gag cgc gca ttg gac gca tac gat 1344 Ile Val Cys Thr Gln Thr Ala Ser Glu Arg Ala Leu Asp Ala Tyr Asp 435 440 445 tta gct gaa tat gct cga gag atc tac ggc gat gag cgt gtg cac gtc 1392 Leu Ala Glu Tyr Ala Arg Glu Ile Tyr Gly Asp Glu Arg Val His Val 450 455 460 caa gaa gat ctt gct ggc gcg gta gaa ctc gct att gaa cta gca gaa 1440 Gln Glu Asp Leu Ala Gly Ala Val Glu Leu Ala Ile Glu Leu Ala Glu 465 470 475 480 gac acc gat gta cag tcc gga tca ggt gtt gtg atc acc ggt tca atc 1488 Asp Thr Asp Val Gln Ser Gly Ser Gly Val Val Ile Thr Gly Ser Ile 485 490 495 gtg acc gcc ggc gat gcg cgc acg ctg ttt gga aag gaa cct gca 1533 Val Thr Ala Gly Asp Ala Arg Thr Leu Phe Gly Lys Glu Pro Ala 500 505 510 tgagcaagcg tgaagaatca att 1556 <210> 698 <211> 511 <212> PRT <213> Corynebacterium glutamicum <400> 698 Gly Ile Gly Leu Val Ala Asn Asn Asp Gly Ile Phe Asp Ser Glu Asn 1 5 10 15 Asp Asp Ile Thr Val Gly Asp Val Thr Leu Gly Glu Thr Gly Leu Ser 20 25 30 Leu Pro Ile Asp Leu Ala Gly Glu Val Glu Ala Pro Ala Ser Glu Glu 35 40 45 Ile Thr Gln Glu Asp Leu Leu Arg Leu Ala Gln Val Glu Ala Glu Leu 50 55 60 Asp Gln Arg Trp Leu Glu Thr Lys Ile Asp Pro Thr Phe Arg Arg Met 65 70 75 80 Ser Tyr Met Met Asp Leu Met Gly Gln Pro Gln Asn Ser Phe Pro Ala 85 90 95 Ile His Val Ala Gly Thr Asn Gly Lys Thr Ser Thr Thr Arg Met Ile 100 105 110 Glu Ser Leu Leu Arg Ala Phe His Arg Arg Thr Gly Arg Thr Thr Ser 115 120 125 Pro His Leu Gln Leu Val Thr Glu Arg Ile Ala Ile Asp Gly Lys Pro 130 135 140 Ile His Pro Arg Asp Phe Val Arg Ile Tyr Glu Glu Ile Lys Pro Tyr 145 150 155 160 Met Glu Met Thr Asp Ala Trp Ser Glu Ala Glu Gly Gly Pro Lys Met 165 170 175 Ser Lys Phe Glu Ala Leu Val Ala Leu Ala Tyr Ala Gly Phe Ala Asp 180 185 190 Ala Pro Val Asp Val Ala Val Val Glu Val Gly Leu Gly Gly Arg Trp 195 200 205 Asp Ala Thr Asn Val Ile Asn Ala Ala Val Ser Val Ile Thr Pro Val 210 215 220 Gly Met Asp His Val Asp Arg Leu Gly Asn Thr Ile Gly Glu Ile Ala 225 230 235 240 Gly Glu Lys Ala Gly Ile Ile Lys Ala Arg Pro Ala Ser Glu Asp Gly 245 250 255 Thr Glu Pro Glu Gly Asn Val Val Ile Val Gly Lys Gln Glu Pro Glu 260 265 270 Ala Met Asn Val Ile Leu Gln Gln Ala Val Asp Val Asp Ala Ala Val 275 280 285 Ala Arg Leu Asn Met Glu Phe Gly Val Val Glu Ser Ala Ile Ala Val 290 295 300 Gly Gly Gln Gln Leu Thr Leu Lys Gly Leu Gly Gly Glu Tyr Thr Asp 305 310 315 320 Ile Phe Leu Pro Leu Ser Gly Ala His Gln Ala Asp Asn Ala Ala Val 325 330 335 Ala Leu Ala Ala Val Glu Ala Phe Phe Gly Ala Ser Ala Gly Arg Pro 340 345 350 Leu Asp Ile Asp Thr Val Arg Glu Gly Phe Ala Gln Val Gln Ser Pro 355 360 365 Gly Arg Leu Glu Arg Leu Arg Ser Ala Pro Thr Val Phe Ile Asp Ala 370 375 380 Ala His Asn Pro His Gly Ala Ala Ala Leu Gly Ala Ala Leu Asp Arg 385 390 395 400 Asp Phe Glu Phe Arg Arg Leu Ile Gly Val Ile Gly Val Leu Cys Asp 405 410 415 Lys Asp Ala Arg Gly Ile Leu Glu Ser Leu Glu Pro Tyr Leu His Glu 420 425 430 Ile Val Cys Thr Gln Thr Ala Ser Glu Arg Ala Leu Asp Ala Tyr Asp 435 440 445 Leu Ala Glu Tyr Ala Arg Glu Ile Tyr Gly Asp Glu Arg Val His Val 450 455 460 Gln Glu Asp Leu Ala Gly Ala Val Glu Leu Ala Ile Glu Leu Ala Glu 465 470 475 480 Asp Thr Asp Val Gln Ser Gly Ser Gly Val Val Ile Thr Gly Ser Ile 485 490 495 Val Thr Ala Gly Asp Ala Arg Thr Leu Phe Gly Lys Glu Pro Ala 500 505 510 <210> 699 <211> 600 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(577) <223> RXA01517 <400> 699 tccataagcc caaagcaccg atcccacgta cttttgctga cgtcgcggtg gttgcccgac 60 gttccaggaa atccatggct gctggaagga gcaacgccta atg cat gca gtt ttg 115 Met His Ala Val Leu 1 5 tcc atc ggt tcc aac atg gat gat cgc tac gcg ctg ctc aac aca gtg 163 Ser Ile Gly Ser Asn Met Asp Asp Arg Tyr Ala Leu Leu Asn Thr Val 10 15 20 atc gag gaa ttc aaa gat gag atc gtg gcg cag tct gcg atc tac tca 211 Ile Glu Glu Phe Lys Asp Glu Ile Val Ala Gln Ser Ala Ile Tyr Ser 25 30 35 acc cca ccg tgg ggc att gag gat cag gat gaa ttc ctc aac gca gtg 259 Thr Pro Pro Trp Gly Ile Glu Asp Gln Asp Glu Phe Leu Asn Ala Val 40 45 50 ctc gtt gtt gag gtt gaa gaa acc ccc atc gag ttg ctg cgc cgt ggc 307 Leu Val Val Glu Val Glu Glu Thr Pro Ile Glu Leu Leu Arg Arg Gly 55 60 65 caa aaa ctc gaa gaa gcc gcc gag cgg gtc cgc gtc cgc aaa tgg ggg 355 Gln Lys Leu Glu Glu Ala Ala Glu Arg Val Arg Val Arg Lys Trp Gly 70 75 80 85 cca cgc acc ctc gat gtg gat atc gtg cag atc att aaa gat ggg gaa 403 Pro Arg Thr Leu Asp Val Asp Ile Val Gln Ile Ile Lys Asp Gly Glu 90 95 100 gag atc ctt tct gag gat ccc gaa ctg acc ttg cca cac cct tgg gct 451 Glu Ile Leu Ser Glu Asp Pro Glu Leu Thr Leu Pro His Pro Trp Ala 105 110 115 tgg cag cgt gcc ttc gtg ttg atc cct tgg ttg gaa gca gaa cct gat 499 Trp Gln Arg Ala Phe Val Leu Ile Pro Trp Leu Glu Ala Glu Pro Asp 120 125 130 gcc gtc ctg cac ggc acg acc att gca gaa cat gtg gat aat ctt gat 547 Ala Val Leu His Gly Thr Thr Ile Ala Glu His Val Asp Asn Leu Asp 135 140 145 ccc aca gac att gaa ggt gtc acc aag att taaggagtcg tggctttcat 597 Pro Thr Asp Ile Glu Gly Val Thr Lys Ile 150 155 gca 600 <210> 700 <211> 159 <212> PRT <213> Corynebacterium glutamicum <400> 700 Met His Ala Val Leu Ser Ile Gly Ser Asn Met Asp Asp Arg Tyr Ala 1 5 10 15 Leu Leu Asn Thr Val Ile Glu Glu Phe Lys Asp Glu Ile Val Ala Gln 20 25 30 Ser Ala Ile Tyr Ser Thr Pro Pro Trp Gly Ile Glu Asp Gln Asp Glu 35 40 45 Phe Leu Asn Ala Val Leu Val Val Glu Val Glu Glu Thr Pro Ile Glu 50 55 60 Leu Leu Arg Arg Gly Gln Lys Leu Glu Glu Ala Ala Glu Arg Val Arg 65 70 75 80 Val Arg Lys Trp Gly Pro Arg Thr Leu Asp Val Asp Ile Val Gln Ile 85 90 95 Ile Lys Asp Gly Glu Glu Ile Leu Ser Glu Asp Pro Glu Leu Thr Leu 100 105 110 Pro His Pro Trp Ala Trp Gln Arg Ala Phe Val Leu Ile Pro Trp Leu 115 120 125 Glu Ala Glu Pro Asp Ala Val Leu His Gly Thr Thr Ile Ala Glu His 130 135 140 Val Asp Asn Leu Asp Pro Thr Asp Ile Glu Gly Val Thr Lys Ile 145 150 155 <210> 701 <211> 1983 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1960) <223> RXA00579 <400> 701 tcgtctaagt ttttctttga gttttcatat gtagaaggca tcgtcggctt cggcctggcg 60 gtgcttttct cgttgttttg tggttttgtc agaggatgtc atg cgc gtt tta att 115 Met Arg Val Leu Ile 1 5 att gat aat tat gat tct ttc acg ttt aat ctc gcc acc tat gtg gaa 163 Ile Asp Asn Tyr Asp Ser Phe Thr Phe Asn Leu Ala Thr Tyr Val Glu 10 15 20 gag gtt acg ggt cag gca cct gtg gtg gtg cct aat gat caa gaa ata 211 Glu Val Thr Gly Gln Ala Pro Val Val Val Pro Asn Asp Gln Glu Ile 25 30 35 gat gag atg ctt ttc gac gcc gtc atc ctc tca cct ggc ccg ggc cac 259 Asp Glu Met Leu Phe Asp Ala Val Ile Leu Ser Pro Gly Pro Gly His 40 45 50 gcc ggc gtt gcg gct gat ttt ggt atc tgt gca ggc gtc att gag cgt 307 Ala Gly Val Ala Ala Asp Phe Gly Ile Cys Ala Gly Val Ile Glu Arg 55 60 65 gca cgc gtt ccg att ttg ggt gtg tgt tta ggc cac cag ggc att gcg 355 Ala Arg Val Pro Ile Leu Gly Val Cys Leu Gly His Gln Gly Ile Ala 70 75 80 85 ttg gcc tat ggc ggt gat gtt gat ttg gcg ccc agg ccg gtc cac ggt 403 Leu Ala Tyr Gly Gly Asp Val Asp Leu Ala Pro Arg Pro Val His Gly 90 95 100 gag gtt tcg cag atc acc cat gat ggt tca ggt tta ttt gca ggc atc 451 Glu Val Ser Gln Ile Thr His Asp Gly Ser Gly Leu Phe Ala Gly Ile 105 110 115 cct gaa acg ttt gag gcg gtg cgt tat cac tcg atg gtg gca acc cgc 499 Pro Glu Thr Phe Glu Ala Val Arg Tyr His Ser Met Val Ala Thr Arg 120 125 130 ttg ccg gag tca ttg aaa gct aca gct acc agc gat gat ggt ttg atc 547 Leu Pro Glu Ser Leu Lys Ala Thr Ala Thr Ser Asp Asp Gly Leu Ile 135 140 145 atg gca ttg gca cat gaa gtg ctt ccg cag tgg ggt gtg caa ttt cat 595 Met Ala Leu Ala His Glu Val Leu Pro Gln Trp Gly Val Gln Phe His 150 155 160 165 ccg gaa tct att ggt gga caa ttc ggc cat cag atc att aag aac ttc 643 Pro Glu Ser Ile Gly Gly Gln Phe Gly His Gln Ile Ile Lys Asn Phe 170 175 180 ctt aat tta gcg cgc aca tat cgc tgg caa ctc acg gag aaa act att 691 Leu Asn Leu Ala Arg Thr Tyr Arg Trp Gln Leu Thr Glu Lys Thr Ile 185 190 195 ccg ctc agc gtt gat tca gca gcg gtt ttt gaa aca ttc ttt gcc cat 739 Pro Leu Ser Val Asp Ser Ala Ala Val Phe Glu Thr Phe Phe Ala His 200 205 210 tcc tcc cat gct ttt tgg ctc gat gat gcc caa gga acc agc tat ctt 787 Ser Ser His Ala Phe Trp Leu Asp Asp Ala Gln Gly Thr Ser Tyr Leu 215 220 225 ggt gat gcc agc ggt cct ctc gca cgc aca aaa acc cat aat gtc ggc 835 Gly Asp Ala Ser Gly Pro Leu Ala Arg Thr Lys Thr His Asn Val Gly 230 235 240 245 gag ggg gat ttc ttc acc tgg cta aag gag gat ctc gcc gcc aac tca 883 Glu Gly Asp Phe Phe Thr Trp Leu Lys Glu Asp Leu Ala Ala Asn Ser 250 255 260 gtt gcg ccc ggt caa ggt ttt cgt ctt ggc tgg gtt ggt tac gtt ggt 931 Val Ala Pro Gly Gln Gly Phe Arg Leu Gly Trp Val Gly Tyr Val Gly 265 270 275 tat gag ctt aaa gcg gaa gct ggc gca cgg gct gcg cac act tcg agt 979 Tyr Glu Leu Lys Ala Glu Ala Gly Ala Arg Ala Ala His Thr Ser Ser 280 285 290 ctt ccg gat gcg cac ctc att ttt gcc gat cgc gcc atc gca gtg gaa 1027 Leu Pro Asp Ala His Leu Ile Phe Ala Asp Arg Ala Ile Ala Val Glu 295 300 305 tcg gat cag gtt cgg ttg ctg gcg ttg ggg gag cag gac gag tgg ttt 1075 Ser Asp Gln Val Arg Leu Leu Ala Leu Gly Glu Gln Asp Glu Trp Phe 310 315 320 325 gaa gaa acc atc aag aag ctg cat aat ctt gtc gcc ccg cgg ata cct 1123 Glu Glu Thr Ile Lys Lys Leu His Asn Leu Val Ala Pro Arg Ile Pro 330 335 340 gcg tcc gga cac ctc gct ttg cag gtt cga gat tcc aaa gat gag tat 1171 Ala Ser Gly His Leu Ala Leu Gln Val Arg Asp Ser Lys Asp Glu Tyr 345 350 355 ctc gac aaa att cgc aga gcc cag gag ctg att act cgc ggc gaa tcg 1219 Leu Asp Lys Ile Arg Arg Ala Gln Glu Leu Ile Thr Arg Gly Glu Ser 360 365 370 tat gaa atc tgc ctg acc aca aaa ctt cag ggc acc act gat gtg gcc 1267 Tyr Glu Ile Cys Leu Thr Thr Lys Leu Gln Gly Thr Thr Asp Val Ala 375 380 385 cct ctg gct gcc tat cta gca ctg cgt ggg gcc aat ccc acc gca tat 1315 Pro Leu Ala Ala Tyr Leu Ala Leu Arg Gly Ala Asn Pro Thr Ala Tyr 390 395 400 405 ggt gcg tat ctt cag ctg ggg gat acc tct att ttg agt tcc tcg ccg 1363 Gly Ala Tyr Leu Gln Leu Gly Asp Thr Ser Ile Leu Ser Ser Ser Pro 410 415 420 gag cgg ttc atc acc att gat tcg gca ggg tat gtg gaa tca aag ccc 1411 Glu Arg Phe Ile Thr Ile Asp Ser Ala Gly Tyr Val Glu Ser Lys Pro 425 430 435 att aaa ggc acc agg ccg cgt ggg cga aca gcg caa gaa gac caa gaa 1459 Ile Lys Gly Thr Arg Pro Arg Gly Arg Thr Ala Gln Glu Asp Gln Glu 440 445 450 atc att gct gag ctg cgc agt aat cct aaa gat cgt gca gaa aac ttg 1507 Ile Ile Ala Glu Leu Arg Ser Asn Pro Lys Asp Arg Ala Glu Asn Leu 455 460 465 atg atc gtg gat ttg gtc cgc aac gac tta gcc cgc ggc gct ttg ccc 1555 Met Ile Val Asp Leu Val Arg Asn Asp Leu Ala Arg Gly Ala Leu Pro 470 475 480 485 acc aca gtt aaa aca tcc aag ctt ttc gac gtc gaa acc tac gcc aca 1603 Thr Thr Val Lys Thr Ser Lys Leu Phe Asp Val Glu Thr Tyr Ala Thr 490 495 500 gtc cac caa ctt gtc agc acc gtc tct gca gag ttg ggg cca cgc agt 1651 Val His Gln Leu Val Ser Thr Val Ser Ala Glu Leu Gly Pro Arg Ser 505 510 515 ccg att gag tgc gtg cgc gca gca ttc ccc ggt ggt tcg atg act ggt 1699 Pro Ile Glu Cys Val Arg Ala Ala Phe Pro Gly Gly Ser Met Thr Gly 520 525 530 gcc cca aag ctg cgc acc atg gag atc atc gat gag ctg gag gca gct 1747 Ala Pro Lys Leu Arg Thr Met Glu Ile Ile Asp Glu Leu Glu Ala Ala 535 540 545 cct cgc ggt att tac tca ggt ggc ttg gga tat ttt tcc ctc gac ggc 1795 Pro Arg Gly Ile Tyr Ser Gly Gly Leu Gly Tyr Phe Ser Leu Asp Gly 550 555 560 565 gca gtt gat ctc tcc atg gtg atc aga act ctc gtc atc cag aac aat 1843 Ala Val Asp Leu Ser Met Val Ile Arg Thr Leu Val Ile Gln Asn Asn 570 575 580 cac gtg gag tac gga gtg ggc ggt gca ctt ctt gct ctg tct gat ccg 1891 His Val Glu Tyr Gly Val Gly Gly Ala Leu Leu Ala Leu Ser Asp Pro 585 590 595 gag gct gag tgg gag gaa atc cgc gtt aaa tca cgg cct ctg ctg aat 1939 Glu Ala Glu Trp Glu Glu Ile Arg Val Lys Ser Arg Pro Leu Leu Asn 600 605 610 ttg ttt ggg gtt gaa ttc cca tgacgtacct cgtgtgggac ggt 1983 Leu Phe Gly Val Glu Phe Pro 615 620 <210> 702 <211> 620 <212> PRT <213> Corynebacterium glutamicum <400> 702 Met Arg Val Leu Ile Ile Asp Asn Tyr Asp Ser Phe Thr Phe Asn Leu 1 5 10 15 Ala Thr Tyr Val Glu Glu Val Thr Gly Gln Ala Pro Val Val Val Pro 20 25 30 Asn Asp Gln Glu Ile Asp Glu Met Leu Phe Asp Ala Val Ile Leu Ser 35 40 45 Pro Gly Pro Gly His Ala Gly Val Ala Ala Asp Phe Gly Ile Cys Ala 50 55 60 Gly Val Ile Glu Arg Ala Arg Val Pro Ile Leu Gly Val Cys Leu Gly 65 70 75 80 His Gln Gly Ile Ala Leu Ala Tyr Gly Gly Asp Val Asp Leu Ala Pro 85 90 95 Arg Pro Val His Gly Glu Val Ser Gln Ile Thr His Asp Gly Ser Gly 100 105 110 Leu Phe Ala Gly Ile Pro Glu Thr Phe Glu Ala Val Arg Tyr His Ser 115 120 125 Met Val Ala Thr Arg Leu Pro Glu Ser Leu Lys Ala Thr Ala Thr Ser 130 135 140 Asp Asp Gly Leu Ile Met Ala Leu Ala His Glu Val Leu Pro Gln Trp 145 150 155 160 Gly Val Gln Phe His Pro Glu Ser Ile Gly Gly Gln Phe Gly His Gln 165 170 175 Ile Ile Lys Asn Phe Leu Asn Leu Ala Arg Thr Tyr Arg Trp Gln Leu 180 185 190 Thr Glu Lys Thr Ile Pro Leu Ser Val Asp Ser Ala Ala Val Phe Glu 195 200 205 Thr Phe Phe Ala His Ser Ser His Ala Phe Trp Leu Asp Asp Ala Gln 210 215 220 Gly Thr Ser Tyr Leu Gly Asp Ala Ser Gly Pro Leu Ala Arg Thr Lys 225 230 235 240 Thr His Asn Val Gly Glu Gly Asp Phe Phe Thr Trp Leu Lys Glu Asp 245 250 255 Leu Ala Ala Asn Ser Val Ala Pro Gly Gln Gly Phe Arg Leu Gly Trp 260 265 270 Val Gly Tyr Val Gly Tyr Glu Leu Lys Ala Glu Ala Gly Ala Arg Ala 275 280 285 Ala His Thr Ser Ser Leu Pro Asp Ala His Leu Ile Phe Ala Asp Arg 290 295 300 Ala Ile Ala Val Glu Ser Asp Gln Val Arg Leu Leu Ala Leu Gly Glu 305 310 315 320 Gln Asp Glu Trp Phe Glu Glu Thr Ile Lys Lys Leu His Asn Leu Val 325 330 335 Ala Pro Arg Ile Pro Ala Ser Gly His Leu Ala Leu Gln Val Arg Asp 340 345 350 Ser Lys Asp Glu Tyr Leu Asp Lys Ile Arg Arg Ala Gln Glu Leu Ile 355 360 365 Thr Arg Gly Glu Ser Tyr Glu Ile Cys Leu Thr Thr Lys Leu Gln Gly 370 375 380 Thr Thr Asp Val Ala Pro Leu Ala Ala Tyr Leu Ala Leu Arg Gly Ala 385 390 395 400 Asn Pro Thr Ala Tyr Gly Ala Tyr Leu Gln Leu Gly Asp Thr Ser Ile 405 410 415 Leu Ser Ser Ser Pro Glu Arg Phe Ile Thr Ile Asp Ser Ala Gly Tyr 420 425 430 Val Glu Ser Lys Pro Ile Lys Gly Thr Arg Pro Arg Gly Arg Thr Ala 435 440 445 Gln Glu Asp Gln Glu Ile Ile Ala Glu Leu Arg Ser Asn Pro Lys Asp 450 455 460 Arg Ala Glu Asn Leu Met Ile Val Asp Leu Val Arg Asn Asp Leu Ala 465 470 475 480 Arg Gly Ala Leu Pro Thr Thr Val Lys Thr Ser Lys Leu Phe Asp Val 485 490 495 Glu Thr Tyr Ala Thr Val His Gln Leu Val Ser Thr Val Ser Ala Glu 500 505 510 Leu Gly Pro Arg Ser Pro Ile Glu Cys Val Arg Ala Ala Phe Pro Gly 515 520 525 Gly Ser Met Thr Gly Ala Pro Lys Leu Arg Thr Met Glu Ile Ile Asp 530 535 540 Glu Leu Glu Ala Ala Pro Arg Gly Ile Tyr Ser Gly Gly Leu Gly Tyr 545 550 555 560 Phe Ser Leu Asp Gly Ala Val Asp Leu Ser Met Val Ile Arg Thr Leu 565 570 575 Val Ile Gln Asn Asn His Val Glu Tyr Gly Val Gly Gly Ala Leu Leu 580 585 590 Ala Leu Ser Asp Pro Glu Ala Glu Trp Glu Glu Ile Arg Val Lys Ser 595 600 605 Arg Pro Leu Leu Asn Leu Phe Gly Val Glu Phe Pro 610 615 620 <210> 703 <211> 747 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(724) <223> RXA00958 <400> 703 attctaatcc tcaatctgaa gccgatgaga cgttgcacaa ggcgtatgcc gtgttgaatg 60 ccattgcgct tgctgctggt tccactttgg aggtcatccg atg aca cac gtt gtt 115 Met Thr His Val Val 1 5 ctc att gat aat cac gat tct ttt gtc tac aac ctg gtg gat gcg ttc 163 Leu Ile Asp Asn His Asp Ser Phe Val Tyr Asn Leu Val Asp Ala Phe 10 15 20 gcc gtg gcc ggt tat aag tgc acg gtg ttc cgc aat acg gtg cca gtg 211 Ala Val Ala Gly Tyr Lys Cys Thr Val Phe Arg Asn Thr Val Pro Val 25 30 35 gaa acc att ttg gca gcc aac ccg gac ctg atc tgc ctt tca cct gga 259 Glu Thr Ile Leu Ala Ala Asn Pro Asp Leu Ile Cys Leu Ser Pro Gly 40 45 50 cct ggt tac cct gcc gat gcg ggc aac atg atg gcg ctg atc gag cgc 307 Pro Gly Tyr Pro Ala Asp Ala Gly Asn Met Met Ala Leu Ile Glu Arg 55 60 65 aca ctc ggc cag att cct tta ctg ggt att tgc ctc ggc tac cag gca 355 Thr Leu Gly Gln Ile Pro Leu Leu Gly Ile Cys Leu Gly Tyr Gln Ala 70 75 80 85 ctc atc gaa tac cac ggc ggc aag gtt gag cct tgt ggc cct gtg cac 403 Leu Ile Glu Tyr His Gly Gly Lys Val Glu Pro Cys Gly Pro Val His 90 95 100 ggc acc acc gac aac atg atc ctt act gat gca ggt gtg cag agc cct 451 Gly Thr Thr Asp Asn Met Ile Leu Thr Asp Ala Gly Val Gln Ser Pro 105 110 115 gtt ttt gca ggt ctt gcc act gat gtt gag cct gat cat cca gaa atc 499 Val Phe Ala Gly Leu Ala Thr Asp Val Glu Pro Asp His Pro Glu Ile 120 125 130 cca ggc cgc aag gtt cca att ggc cgt tat cac tca ctg ggc tgc gtg 547 Pro Gly Arg Lys Val Pro Ile Gly Arg Tyr His Ser Leu Gly Cys Val 135 140 145 gtt gcc cca gac ggt att gaa tca cta ggt acc tgt tcc tcg gag att 595 Val Ala Pro Asp Gly Ile Glu Ser Leu Gly Thr Cys Ser Ser Glu Ile 150 155 160 165 ggt gat gtc atc atg gcg gca cgc acc acc gat gga aag gcc att ggc 643 Gly Asp Val Ile Met Ala Ala Arg Thr Thr Asp Gly Lys Ala Ile Gly 170 175 180 ctg cag ttt cac cct gag tca gtg cta agc cca acg ggt cct gtc att 691 Leu Gln Phe His Pro Glu Ser Val Leu Ser Pro Thr Gly Pro Val Ile 185 190 195 ttg tcc cgc tgt gtc gaa cag ctt ctc gcg aac taataaaaaa aggatttgat 744 Leu Ser Arg Cys Val Glu Gln Leu Leu Ala Asn 200 205 tca 747 <210> 704 <211> 208 <212> PRT <213> Corynebacterium glutamicum <400> 704 Met Thr His Val Val Leu Ile Asp Asn His Asp Ser Phe Val Tyr Asn 1 5 10 15 Leu Val Asp Ala Phe Ala Val Ala Gly Tyr Lys Cys Thr Val Phe Arg 20 25 30 Asn Thr Val Pro Val Glu Thr Ile Leu Ala Ala Asn Pro Asp Leu Ile 35 40 45 Cys Leu Ser Pro Gly Pro Gly Tyr Pro Ala Asp Ala Gly Asn Met Met 50 55 60 Ala Leu Ile Glu Arg Thr Leu Gly Gln Ile Pro Leu Leu Gly Ile Cys 65 70 75 80 Leu Gly Tyr Gln Ala Leu Ile Glu Tyr His Gly Gly Lys Val Glu Pro 85 90 95 Cys Gly Pro Val His Gly Thr Thr Asp Asn Met Ile Leu Thr Asp Ala 100 105 110 Gly Val Gln Ser Pro Val Phe Ala Gly Leu Ala Thr Asp Val Glu Pro 115 120 125 Asp His Pro Glu Ile Pro Gly Arg Lys Val Pro Ile Gly Arg Tyr His 130 135 140 Ser Leu Gly Cys Val Val Ala Pro Asp Gly Ile Glu Ser Leu Gly Thr 145 150 155 160 Cys Ser Ser Glu Ile Gly Asp Val Ile Met Ala Ala Arg Thr Thr Asp 165 170 175 Gly Lys Ala Ile Gly Leu Gln Phe His Pro Glu Ser Val Leu Ser Pro 180 185 190 Thr Gly Pro Val Ile Leu Ser Arg Cys Val Glu Gln Leu Leu Ala Asn 195 200 205 <210> 705 <211> 1266 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1243) <223> RXA02790 <400> 705 tggatgctcg cacccgagcc cttgaaccac aatccacaga cacccaagat ttcgacgaga 60 agggaaattt cccaggatga accaaatccg aaaccgccgg atg gag ccc gtc tac 115 Met Glu Pro Val Tyr 1 5 gta aag cgc cgc caa cgg ttt att gcc gtg acg atc gct tca ctc atc 163 Val Lys Arg Arg Gln Arg Phe Ile Ala Val Thr Ile Ala Ser Leu Ile 10 15 20 ctc att atc ggt gcc atc atc tat atc ggt gta gcc acc tca aac cgg 211 Leu Ile Ile Gly Ala Ile Ile Tyr Ile Gly Val Ala Thr Ser Asn Arg 25 30 35 acg cca cat gac tat gaa ggc tcc gga aac ggt gtg gtt cag ctg gtc 259 Thr Pro His Asp Tyr Glu Gly Ser Gly Asn Gly Val Val Gln Leu Val 40 45 50 gaa atc cct gaa ggt tcc tcc ata tca gag ctc ggc cca gag ttg gaa 307 Glu Ile Pro Glu Gly Ser Ser Ile Ser Glu Leu Gly Pro Glu Leu Glu 55 60 65 gaa cga gat atc gtg gcc acc aac tca gcg ttc caa aca gcg gcc agc 355 Glu Arg Asp Ile Val Ala Thr Asn Ser Ala Phe Gln Thr Ala Ala Ser 70 75 80 85 aac aac ccc aac gcg ggt agt gta cag cca ggt ttc tac cgt ctg cag 403 Asn Asn Pro Asn Ala Gly Ser Val Gln Pro Gly Phe Tyr Arg Leu Gln 90 95 100 gaa caa atg aac gca gca gct gca gtg tcg gct ctg ctt gat cca gac 451 Glu Gln Met Asn Ala Ala Ala Ala Val Ser Ala Leu Leu Asp Pro Asp 105 110 115 aac cag gtt gat ctc ctc gac att cac ggc ggc gcc acc ttg atg gac 499 Asn Gln Val Asp Leu Leu Asp Ile His Gly Gly Ala Thr Leu Met Asp 120 125 130 gtc act gtt gtc ggc gga aac acc cgc gcg gga atc tac tcc cag atc 547 Val Thr Val Val Gly Gly Asn Thr Arg Ala Gly Ile Tyr Ser Gln Ile 135 140 145 gca gcc gtg acc tgc acc gaa ggc tcc gcc aac tgc atc acc gct gag 595 Ala Ala Val Thr Cys Thr Glu Gly Ser Ala Asn Cys Ile Thr Ala Glu 150 155 160 165 gat ttg cag cag gtt gcc tcc acc gtg tcg cct gca gaa ttg ggt gtc 643 Asp Leu Gln Gln Val Ala Ser Thr Val Ser Pro Ala Glu Leu Gly Val 170 175 180 cca gat tgg gca atc gct gct gtg gaa gct cgc gga act gat cca aag 691 Pro Asp Trp Ala Ile Ala Ala Val Glu Ala Arg Gly Thr Asp Pro Lys 185 190 195 cgc ctc gaa ggc ctg atc atg cct ggc caa tac gtg gtg gat cca tcc 739 Arg Leu Glu Gly Leu Ile Met Pro Gly Gln Tyr Val Val Asp Pro Ser 200 205 210 aac gac gcc cag gga atc ctc acc gat ctg atc acg cga tca gca aac 787 Asn Asp Ala Gln Gly Ile Leu Thr Asp Leu Ile Thr Arg Ser Ala Asn 215 220 225 cat ttc caa gaa acc gac atc acg ggc cgt gca gat gcc atc gga ctt 835 His Phe Gln Glu Thr Asp Ile Thr Gly Arg Ala Asp Ala Ile Gly Leu 230 235 240 245 act cca tat gag ctg gtc acc gca gca tct tta atc gag cgc gaa gca 883 Thr Pro Tyr Glu Leu Val Thr Ala Ala Ser Leu Ile Glu Arg Glu Ala 250 255 260 cca gca gga gat ttt gat aag gtc gcc cgc gtc atc ttg aac cgt ctc 931 Pro Ala Gly Asp Phe Asp Lys Val Ala Arg Val Ile Leu Asn Arg Leu 265 270 275 gcc gag cca atg cag ctg caa ttc gac tcc acc gtc aac tac ggt ctg 979 Ala Glu Pro Met Gln Leu Gln Phe Asp Ser Thr Val Asn Tyr Gly Leu 280 285 290 tct gaa caa gaa gta gca acc acc gac gaa gac cgt cag acc gtc acc 1027 Ser Glu Gln Glu Val Ala Thr Thr Asp Glu Asp Arg Gln Thr Val Thr 295 300 305 cca tgg aac act tac gcc atg gac ggc ctg cca caa acc ccc atc gcc 1075 Pro Trp Asn Thr Tyr Ala Met Asp Gly Leu Pro Gln Thr Pro Ile Ala 310 315 320 325 gca gta tcc acc gaa gca ctc caa gcc atg gaa aac cct gca gaa gga 1123 Ala Val Ser Thr Glu Ala Leu Gln Ala Met Glu Asn Pro Ala Glu Gly 330 335 340 aac tgg ctg tac ttt gtc acc atc gac acc gat gga acc acc gtg ttc 1171 Asn Trp Leu Tyr Phe Val Thr Ile Asp Thr Asp Gly Thr Thr Val Phe 345 350 355 aac gac acc ttc gaa gag cac gaa gcc gac att gag caa gct ttg aac 1219 Asn Asp Thr Phe Glu Glu His Glu Ala Asp Ile Glu Gln Ala Leu Asn 360 365 370 agt ggc gtt cta gac agc aac cga taaggatcag cgaataaaat tgg 1266 Ser Gly Val Leu Asp Ser Asn Arg 375 380 <210> 706 <211> 381 <212> PRT <213> Corynebacterium glutamicum <400> 706 Met Glu Pro Val Tyr Val Lys Arg Arg Gln Arg Phe Ile Ala Val Thr 1 5 10 15 Ile Ala Ser Leu Ile Leu Ile Ile Gly Ala Ile Ile Tyr Ile Gly Val 20 25 30 Ala Thr Ser Asn Arg Thr Pro His Asp Tyr Glu Gly Ser Gly Asn Gly 35 40 45 Val Val Gln Leu Val Glu Ile Pro Glu Gly Ser Ser Ile Ser Glu Leu 50 55 60 Gly Pro Glu Leu Glu Glu Arg Asp Ile Val Ala Thr Asn Ser Ala Phe 65 70 75 80 Gln Thr Ala Ala Ser Asn Asn Pro Asn Ala Gly Ser Val Gln Pro Gly 85 90 95 Phe Tyr Arg Leu Gln Glu Gln Met Asn Ala Ala Ala Ala Val Ser Ala 100 105 110 Leu Leu Asp Pro Asp Asn Gln Val Asp Leu Leu Asp Ile His Gly Gly 115 120 125 Ala Thr Leu Met Asp Val Thr Val Val Gly Gly Asn Thr Arg Ala Gly 130 135 140 Ile Tyr Ser Gln Ile Ala Ala Val Thr Cys Thr Glu Gly Ser Ala Asn 145 150 155 160 Cys Ile Thr Ala Glu Asp Leu Gln Gln Val Ala Ser Thr Val Ser Pro 165 170 175 Ala Glu Leu Gly Val Pro Asp Trp Ala Ile Ala Ala Val Glu Ala Arg 180 185 190 Gly Thr Asp Pro Lys Arg Leu Glu Gly Leu Ile Met Pro Gly Gln Tyr 195 200 205 Val Val Asp Pro Ser Asn Asp Ala Gln Gly Ile Leu Thr Asp Leu Ile 210 215 220 Thr Arg Ser Ala Asn His Phe Gln Glu Thr Asp Ile Thr Gly Arg Ala 225 230 235 240 Asp Ala Ile Gly Leu Thr Pro Tyr Glu Leu Val Thr Ala Ala Ser Leu 245 250 255 Ile Glu Arg Glu Ala Pro Ala Gly Asp Phe Asp Lys Val Ala Arg Val 260 265 270 Ile Leu Asn Arg Leu Ala Glu Pro Met Gln Leu Gln Phe Asp Ser Thr 275 280 285 Val Asn Tyr Gly Leu Ser Glu Gln Glu Val Ala Thr Thr Asp Glu Asp 290 295 300 Arg Gln Thr Val Thr Pro Trp Asn Thr Tyr Ala Met Asp Gly Leu Pro 305 310 315 320 Gln Thr Pro Ile Ala Ala Val Ser Thr Glu Ala Leu Gln Ala Met Glu 325 330 335 Asn Pro Ala Glu Gly Asn Trp Leu Tyr Phe Val Thr Ile Asp Thr Asp 340 345 350 Gly Thr Thr Val Phe Asn Asp Thr Phe Glu Glu His Glu Ala Asp Ile 355 360 365 Glu Gln Ala Leu Asn Ser Gly Val Leu Asp Ser Asn Arg 370 375 380 <210> 707 <211> 579 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(556) <223> RXA00106 <400> 707 tggagctcaa caaggcagcg tacatgtttg agtacagctt cgatgacatc accgtgtccg 60 gctacgatcc acacccattg atccgcggca aggtcgccgt atg atc ggt gcg att 115 Met Ile Gly Ala Ile 1 5 tgg gca caa ggc cgt gac ggc atc atc ggc gac ggc acc gac atg ccc 163 Trp Ala Gln Gly Arg Asp Gly Ile Ile Gly Asp Gly Thr Asp Met Pro 10 15 20 tgg cac atc ccg gaa gac ctc aaa cac ttc aag aaa acc acc atg ggc 211 Trp His Ile Pro Glu Asp Leu Lys His Phe Lys Lys Thr Thr Met Gly 25 30 35 cag ccg gtc atc atg ggt cgt cgc acg tgg gag tct ttg ccg ttc aag 259 Gln Pro Val Ile Met Gly Arg Arg Thr Trp Glu Ser Leu Pro Phe Lys 40 45 50 ccg ctt ccc ggc cgc gag aac ttc att ctc tcc tca cgc gag ccc ggc 307 Pro Leu Pro Gly Arg Glu Asn Phe Ile Leu Ser Ser Arg Glu Pro Gly 55 60 65 gac tgg tcc gcc ggc ggc aca gtg gtc acc gaa atc cct aaa agc ggc 355 Asp Trp Ser Ala Gly Gly Thr Val Val Thr Glu Ile Pro Lys Ser Gly 70 75 80 85 tgg atc atg ggc ggc ggc gag gtc tac aag gcc acc gtc ggc agc gcc 403 Trp Ile Met Gly Gly Gly Glu Val Tyr Lys Ala Thr Val Gly Ser Ala 90 95 100 gac gtt tta gaa ata acg ctt atc gac gcc acc ttc gat gtt tcc act 451 Asp Val Leu Glu Ile Thr Leu Ile Asp Ala Thr Phe Asp Val Ser Thr 105 110 115 ccc gtc tac gca ccc gaa atc ccg gcg aac ttc aac ctc gat gac gaa 499 Pro Val Tyr Ala Pro Glu Ile Pro Ala Asn Phe Asn Leu Asp Asp Glu 120 125 130 tcc gag tgg ttt acc tca ggc gag tat cgt tac aag ttc cag cgc tac 547 Ser Glu Trp Phe Thr Ser Gly Glu Tyr Arg Tyr Lys Phe Gln Arg Tyr 135 140 145 atc aag gtt taaggagcaa acaacatgag caa 579 Ile Lys Val 150 <210> 708 <211> 152 <212> PRT <213> Corynebacterium glutamicum <400> 708 Met Ile Gly Ala Ile Trp Ala Gln Gly Arg Asp Gly Ile Ile Gly Asp 1 5 10 15 Gly Thr Asp Met Pro Trp His Ile Pro Glu Asp Leu Lys His Phe Lys 20 25 30 Lys Thr Thr Met Gly Gln Pro Val Ile Met Gly Arg Arg Thr Trp Glu 35 40 45 Ser Leu Pro Phe Lys Pro Leu Pro Gly Arg Glu Asn Phe Ile Leu Ser 50 55 60 Ser Arg Glu Pro Gly Asp Trp Ser Ala Gly Gly Thr Val Val Thr Glu 65 70 75 80 Ile Pro Lys Ser Gly Trp Ile Met Gly Gly Gly Glu Val Tyr Lys Ala 85 90 95 Thr Val Gly Ser Ala Asp Val Leu Glu Ile Thr Leu Ile Asp Ala Thr 100 105 110 Phe Asp Val Ser Thr Pro Val Tyr Ala Pro Glu Ile Pro Ala Asn Phe 115 120 125 Asn Leu Asp Asp Glu Ser Glu Trp Phe Thr Ser Gly Glu Tyr Arg Tyr 130 135 140 Lys Phe Gln Arg Tyr Ile Lys Val 145 150 <210> 709 <211> 2599 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2599) <223> RXN02198 <400> 709 agactagtgg cgctttgcct gtgttgctta ggcggcgttg aaaatgaact acgaatgaaa 60 agttcgggaa ttgtctaatc cgtactaagc tgtctacaca atg tct act tca gtt 115 Met Ser Thr Ser Val 1 5 act tca cca gcc cac aac aac gca cat tcc tcc gaa ttt ttg gat gcg 163 Thr Ser Pro Ala His Asn Asn Ala His Ser Ser Glu Phe Leu Asp Ala 10 15 20 ttg gca aac cat gtg ttg atc ggc gac ggc gcc atg ggc acc cag ctc 211 Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala Met Gly Thr Gln Leu 25 30 35 caa ggc ttt gac ctg gac gtg gaa aag gat ttc ctt gat ctg gag ggg 259 Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe Leu Asp Leu Glu Gly 40 45 50 tgt aat gag att ctc aac gac acc cgc cct gat gtg ttg agg cag att 307 Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp Val Leu Arg Gln Ile 55 60 65 cac cgc gcc tac ttt gag gcg gga gct gac ttg gtt gag acc aat act 355 His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu Val Glu Thr Asn Thr 70 75 80 85 ttt ggt tgc aac ctg ccg aac ttg gcg gat tat gac atc gct gat cgt 403 Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr Asp Ile Ala Asp Arg 90 95 100 tgc cgt gag ctt gcc tac aag ggc act gca gtg gct agg gaa gtg gct 451 Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val Ala Arg Glu Val Ala 105 110 115 gat gag atg ggg ccg ggc cga aac ggc atg cgg cgt ttc gtg gtt ggt 499 Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg Arg Phe Val Val Gly 120 125 130 tcc ctg gga cct gga acg aag ctt cca tcg ctg ggc cat gca ccg tat 547 Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu Gly His Ala Pro Tyr 135 140 145 gca gat ttg cgt ggg cac tac aag gaa gca gcg ctt ggc atc atc gac 595 Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala Leu Gly Ile Ile Asp 150 155 160 165 ggt ggt ggc gat gcc ttt ttg att gag act gct cag gac ttg ctt cag 643 Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala Gln Asp Leu Leu Gln 170 175 180 gtc aag gct gcg gtt cac ggc gtt caa gat gcc atg gct gaa ctt gat 691 Val Lys Ala Ala Val His Gly Val Gln Asp Ala Met Ala Glu Leu Asp 185 190 195 aca ttc ttg ccc att att tgc cac gtc acc gta gag acc acc ggc acc 739 Thr Phe Leu Pro Ile Ile Cys His Val Thr Val Glu Thr Thr Gly Thr 200 205 210 atg ctc atg ggt tct gag atc ggt gcc gcg ttg aca gcg ctg cag cca 787 Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu Thr Ala Leu Gln Pro 215 220 225 ctg ggt atc gac atg att ggt ctg aac tgc gcc acc ggc cca gat gag 835 Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala Thr Gly Pro Asp Glu 230 235 240 245 atg agc gag cac ctg cgt tac ctg tcc aag cac gcc gat att cct gtg 883 Met Ser Glu His Leu Arg Tyr Leu Ser Lys His Ala Asp Ile Pro Val 250 255 260 tcg gtg atg cct aac gca ggt ctt cct gtc ctg ggt aaa aac ggt gca 931 Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu Gly Lys Asn Gly Ala 265 270 275 gaa tac cca ctt gag gct gag gat ttg gcg cag gcg ctg gct gga ttc 979 Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln Ala Leu Ala Gly Phe 280 285 290 gtc tcc gaa tat ggc ctg tcc atg gtg ggt ggt tgt tgt ggc acc aca 1027 Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly Cys Cys Gly Thr Thr 295 300 305 cct gag cac atc cgt gcg gtc cgc gat gcg gtg gtt ggt gtt cca gag 1075 Pro Glu His Ile Arg Ala Val Arg Asp Ala Val Val Gly Val Pro Glu 310 315 320 325 cag gaa acc tcc aca ctg acc aag atc cct gca ggc cct gtt gag cag 1123 Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala Gly Pro Val Glu Gln 330 335 340 gcc tcc cgc gag gtg gag aaa gag gac tcc gtc gcg tcg ctg tac acc 1171 Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val Ala Ser Leu Tyr Thr 345 350 355 tcg gtg cca ttg tcc cag gaa acc ggc att tcc atg atc ggt gag cgc 1219 Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser Met Ile Gly Glu Arg 360 365 370 acc aac tcc aac ggt tcc aag gca ttc cgt gag gca atg ctg tct ggc 1267 Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu Ala Met Leu Ser Gly 375 380 385 gat tgg gaa aag tgt gtg gat att gcc aag cag caa acc cgc gat ggt 1315 Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln Gln Thr Arg Asp Gly 390 395 400 405 gca cac atg ctg gat ctt tgt gtg gat tac gtg gga cga gac ggc acc 1363 Ala His Met Leu Asp Leu Cys Val Asp Tyr Val Gly Arg Asp Gly Thr 410 415 420 gcc gat atg gcg acc ttg gca gca ctt ctt gct acc agc tcc act ttg 1411 Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala Thr Ser Ser Thr Leu 425 430 435 cca atc atg att gac tcc acc gag cca gag gtt att cgc aca ggc ctt 1459 Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val Ile Arg Thr Gly Leu 440 445 450 gag cac ttg ggt gga cga agc atc gtt aac tcc gtc aac ttt gaa gac 1507 Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser Val Asn Phe Glu Asp 455 460 465 ggc gat ggc cct gag tcc cgc tac cag cgc atc atg aaa ctg gta aag 1555 Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile Met Lys Leu Val Lys 470 475 480 485 cag cac ggt gcg gcc gtg gtt gcg ctg acc att gat gag gaa ggc cag 1603 Gln His Gly Ala Ala Val Val Ala Leu Thr Ile Asp Glu Glu Gly Gln 490 495 500 gca cgt acc gct gag cac aag gtg cgc att gct aaa cga ctg att gac 1651 Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala Lys Arg Leu Ile Asp 505 510 515 gat atc acc ggc agc tac ggc ctg gat atc aaa gac atc gtt gtg gac 1699 Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys Asp Ile Val Val Asp 520 525 530 tgc ctg acc ttc ccg atc tct act ggc cag gaa gaa acc agg cga gat 1747 Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu Glu Thr Arg Arg Asp 535 540 545 ggc att gaa acc atc gaa gcc atc cgc gag ctg aag aag ctc tac cca 1795 Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu Lys Lys Leu Tyr Pro 550 555 560 565 gaa atc cac acc acc ctg ggt ctg tcc aat att tcc ttc ggc ctg aac 1843 Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile Ser Phe Gly Leu Asn 570 575 580 cct gct gca cgc cag gtt ctt aac tct gtg ttc ctc aat gag tgc att 1891 Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe Leu Asn Glu Cys Ile 585 590 595 gag gct ggt ctg gac tct gcg att gcg cac agc tcc aag att ttg ccg 1939 Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser Ser Lys Ile Leu Pro 600 605 610 atg aac cgc att gat gat cgc cag cgc gaa gtg gcg ttg gat atg gtc 1987 Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val Ala Leu Asp Met Val 615 620 625 tat gat cgc cgc acc gag gat tac gat ccg ctg cag gaa ttc atg cag 2035 Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu Gln Glu Phe Met Gln 630 635 640 645 ctg ttt gag ggc gtt tct gct gcc gat gcc aag gat gct cgc gct gaa 2083 Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys Asp Ala Arg Ala Glu 650 655 660 cag ctg gcc gct atg cct ttg ttt gag cgt ttg gca cag cgc atc atc 2131 Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu Ala Gln Arg Ile Ile 665 670 675 gac ggc gat aag aat ggc ctt gag gat gat ctg gaa gca ggc atg aag 2179 Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu Glu Ala Gly Met Lys 680 685 690 gag aag tct cct att gcg atc atc aac gag gac ctt ctc aac ggc atg 2227 Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp Leu Leu Asn Gly Met 695 700 705 aag acc gtg ggt gag ctg ttt ggt tcc gga cag atg cag ctg cca ttc 2275 Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln Met Gln Leu Pro Phe 710 715 720 725 gtg ctg caa tcg gca gaa acc atg aaa act gcg gtg gcc tat ttg gaa 2323 Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala Val Ala Tyr Leu Glu 730 735 740 ccg ttc atg gaa gag gaa gca gaa gct acc gga tct gcg cag gca gag 2371 Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly Ser Ala Gln Ala Glu 745 750 755 ggc aag ggc aaa atc gtc gtg gcc acc gtc aag ggt gac gtg cac gat 2419 Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys Gly Asp Val His Asp 760 765 770 atc ggc aag aac ttg gtg gac atc att ttg tcc aac aac ggt tac gac 2467 Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser Asn Asn Gly Tyr Asp 775 780 785 gtg gtg aac ttg ggc atc aag cag cca ctg tcc gcc atg ttg gaa gca 2515 Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser Ala Met Leu Glu Ala 790 795 800 805 gcg gaa gaa cac aaa gca gac gtc atc ggc atg tcg gga ctt ctt gtg 2563 Ala Glu Glu His Lys Ala Asp Val Ile Gly Met Ser Gly Leu Leu Val 810 815 820 aag tcc acc gtg gtg atg aag caa acc atc agc gac 2599 Lys Ser Thr Val Val Met Lys Gln Thr Ile Ser Asp 825 830 <210> 710 <211> 833 <212> PRT <213> Corynebacterium glutamicum <400> 710 Met Ser Thr Ser Val Thr Ser Pro Ala His Asn Asn Ala His Ser Ser 1 5 10 15 Glu Phe Leu Asp Ala Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala 20 25 30 Met Gly Thr Gln Leu Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe 35 40 45 Leu Asp Leu Glu Gly Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp 50 55 60 Val Leu Arg Gln Ile His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu 65 70 75 80 Val Glu Thr Asn Thr Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr 85 90 95 Asp Ile Ala Asp Arg Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val 100 105 110 Ala Arg Glu Val Ala Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg 115 120 125 Arg Phe Val Val Gly Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu 130 135 140 Gly His Ala Pro Tyr Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala 145 150 155 160 Leu Gly Ile Ile Asp Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala 165 170 175 Gln Asp Leu Leu Gln Val Lys Ala Ala Val His Gly Val Gln Asp Ala 180 185 190 Met Ala Glu Leu Asp Thr Phe Leu Pro Ile Ile Cys His Val Thr Val 195 200 205 Glu Thr Thr Gly Thr Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu 210 215 220 Thr Ala Leu Gln Pro Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala 225 230 235 240 Thr Gly Pro Asp Glu Met Ser Glu His Leu Arg Tyr Leu Ser Lys His 245 250 255 Ala Asp Ile Pro Val Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu 260 265 270 Gly Lys Asn Gly Ala Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln 275 280 285 Ala Leu Ala Gly Phe Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly 290 295 300 Cys Cys Gly Thr Thr Pro Glu His Ile Arg Ala Val Arg Asp Ala Val 305 310 315 320 Val Gly Val Pro Glu Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala 325 330 335 Gly Pro Val Glu Gln Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val 340 345 350 Ala Ser Leu Tyr Thr Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser 355 360 365 Met Ile Gly Glu Arg Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu 370 375 380 Ala Met Leu Ser Gly Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln 385 390 395 400 Gln Thr Arg Asp Gly Ala His Met Leu Asp Leu Cys Val Asp Tyr Val 405 410 415 Gly Arg Asp Gly Thr Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala 420 425 430 Thr Ser Ser Thr Leu Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val 435 440 445 Ile Arg Thr Gly Leu Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser 450 455 460 Val Asn Phe Glu Asp Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile 465 470 475 480 Met Lys Leu Val Lys Gln His Gly Ala Ala Val Val Ala Leu Thr Ile 485 490 495 Asp Glu Glu Gly Gln Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala 500 505 510 Lys Arg Leu Ile Asp Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys 515 520 525 Asp Ile Val Val Asp Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu 530 535 540 Glu Thr Arg Arg Asp Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu 545 550 555 560 Lys Lys Leu Tyr Pro Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile 565 570 575 Ser Phe Gly Leu Asn Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe 580 585 590 Leu Asn Glu Cys Ile Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser 595 600 605 Ser Lys Ile Leu Pro Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val 610 615 620 Ala Leu Asp Met Val Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu 625 630 635 640 Gln Glu Phe Met Gln Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys 645 650 655 Asp Ala Arg Ala Glu Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu 660 665 670 Ala Gln Arg Ile Ile Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu 675 680 685 Glu Ala Gly Met Lys Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp 690 695 700 Leu Leu Asn Gly Met Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln 705 710 715 720 Met Gln Leu Pro Phe Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala 725 730 735 Val Ala Tyr Leu Glu Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly 740 745 750 Ser Ala Gln Ala Glu Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys 755 760 765 Gly Asp Val His Asp Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser 770 775 780 Asn Asn Gly Tyr Asp Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser 785 790 795 800 Ala Met Leu Glu Ala Ala Glu Glu His Lys Ala Asp Val Ile Gly Met 805 810 815 Ser Gly Leu Leu Val Lys Ser Thr Val Val Met Lys Gln Thr Ile Ser 820 825 830 Asp <210> 711 <211> 2578 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2578) <223> FRXA02198 <400> 711 agactagtgg cgctttgcct gtgttgctta ggcggcgttg aaaatgaact acgaatgaaa 60 agttcgggaa ttgtctaatc cgtactaagc tgtctacaca atg tct act tca gtt 115 Met Ser Thr Ser Val 1 5 act tca cca gcc cac aac aac gca cat tcc tcc gaa ttt ttg gat gcg 163 Thr Ser Pro Ala His Asn Asn Ala His Ser Ser Glu Phe Leu Asp Ala 10 15 20 ttg gca aac cat gtg ttg atc ggc gac ggc gcc atg ggc acc cag ctc 211 Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala Met Gly Thr Gln Leu 25 30 35 caa ggc ttt gac ctg gac gtg gaa aag gat ttc ctt gat ctg gag ggg 259 Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe Leu Asp Leu Glu Gly 40 45 50 tgt aat gag att ctc aac gac acc cgc cct gat gtg ttg agg cag att 307 Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp Val Leu Arg Gln Ile 55 60 65 cac cgc gcc tac ttt gag gcg gga gct gac ttg gtt gag acc aat act 355 His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu Val Glu Thr Asn Thr 70 75 80 85 ttt ggt tgc aac ctg ccg aac ttg gcg gat tat gac atc gct gat cgt 403 Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr Asp Ile Ala Asp Arg 90 95 100 tgc cgt gag ctt gcc tac aag ggc act gca gtg gct agg gaa gtg gct 451 Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val Ala Arg Glu Val Ala 105 110 115 gat gag atg ggg ccg ggc cga aac ggc atg cgg cgt ttc gtg gtt ggt 499 Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg Arg Phe Val Val Gly 120 125 130 tcc ctg gga cct gga acg aag ctt cca tcg ctg ggc cat gca ccg tat 547 Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu Gly His Ala Pro Tyr 135 140 145 gca gat ttg cgt ggg cac tac aag gaa gca gcg ctt ggc atc atc gac 595 Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala Leu Gly Ile Ile Asp 150 155 160 165 ggt ggt ggc gat gcc ttt ttg att gag act gct cag gac ttg ctt cag 643 Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala Gln Asp Leu Leu Gln 170 175 180 gtc aag gct gcg gtt cac ggc gtt caa gat gcc atg gct gaa ctt gat 691 Val Lys Ala Ala Val His Gly Val Gln Asp Ala Met Ala Glu Leu Asp 185 190 195 aca ttc ttg ccc att att tgc cac gtc acc gta gag acc acc ggc acc 739 Thr Phe Leu Pro Ile Ile Cys His Val Thr Val Glu Thr Thr Gly Thr 200 205 210 atg ctc atg ggt tct gag atc ggt gcc gcg ttg aca gcg ctg cag cca 787 Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu Thr Ala Leu Gln Pro 215 220 225 ctg ggt atc gac atg att ggt ctg aac tgc gcc acc ggc cca gat gag 835 Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala Thr Gly Pro Asp Glu 230 235 240 245 atg agc gag cac ctg cgt tac ctg tcc aag cac gcc gat att cct gtg 883 Met Ser Glu His Leu Arg Tyr Leu Ser Lys His Ala Asp Ile Pro Val 250 255 260 tcg gtg atg cct aac gca ggt ctt cct gtc ctg ggt aaa aac ggt gca 931 Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu Gly Lys Asn Gly Ala 265 270 275 gaa tac cca ctt gag gct gag gat ttg gcg cag gcg ctg gct gga ttc 979 Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln Ala Leu Ala Gly Phe 280 285 290 gtc tcc gaa tat ggc ctg tcc atg gtg ggt ggt tgt tgt ggc acc aca 1027 Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly Cys Cys Gly Thr Thr 295 300 305 cct gag cac atc cgt gcg gtc cgc gat gcg gtg gtt ggt gtt cca gag 1075 Pro Glu His Ile Arg Ala Val Arg Asp Ala Val Val Gly Val Pro Glu 310 315 320 325 cag gaa acc tcc aca ctg acc aag atc cct gca ggc cct gtt gag cag 1123 Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala Gly Pro Val Glu Gln 330 335 340 gcc tcc cgc gag gtg gag aaa gag gac tcc gtc gcg tcg ctg tac acc 1171 Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val Ala Ser Leu Tyr Thr 345 350 355 tcg gtg cca ttg tcc cag gaa acc ggc att tcc atg atc ggt gag cgc 1219 Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser Met Ile Gly Glu Arg 360 365 370 acc aac tcc aac ggt tcc aag gca ttc cgt gag gca atg ctg tct ggc 1267 Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu Ala Met Leu Ser Gly 375 380 385 gat tgg gaa aag tgt gtg gat att gcc aag cag caa acc cgc gat ggt 1315 Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln Gln Thr Arg Asp Gly 390 395 400 405 gca cac atg ctg gat ctt tgt gtg gat tac gtg gga cga gac ggc acc 1363 Ala His Met Leu Asp Leu Cys Val Asp Tyr Val Gly Arg Asp Gly Thr 410 415 420 gcc gat atg gcg acc ttg gca gca ctt ctt gct acc agc tcc act ttg 1411 Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala Thr Ser Ser Thr Leu 425 430 435 cca atc atg att gac tcc acc gag cca gag gtt att cgc aca ggc ctt 1459 Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val Ile Arg Thr Gly Leu 440 445 450 gag cac ttg ggt gga cga agc atc gtt aac tcc gtc aac ttt gaa gac 1507 Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser Val Asn Phe Glu Asp 455 460 465 ggc gat ggc cct gag tcc cgc tac cag cgc atc atg aaa ctg gta aag 1555 Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile Met Lys Leu Val Lys 470 475 480 485 cag cac ggt gcg gcc gtg gtt gcg ctg acc att gat gag gaa ggc cag 1603 Gln His Gly Ala Ala Val Val Ala Leu Thr Ile Asp Glu Glu Gly Gln 490 495 500 gca cgt acc gct gag cac aag gtg cgc att gct aaa cga ctg att gac 1651 Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala Lys Arg Leu Ile Asp 505 510 515 gat atc acc ggc agc tac ggc ctg gat atc aaa gac atc gtt gtg gac 1699 Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys Asp Ile Val Val Asp 520 525 530 tgc ctg acc ttc ccg atc tct act ggc cag gaa gaa acc agg cga gat 1747 Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu Glu Thr Arg Arg Asp 535 540 545 ggc att gaa acc atc gaa gcc atc cgc gag ctg aag aag ctc tac cca 1795 Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu Lys Lys Leu Tyr Pro 550 555 560 565 gaa atc cac acc acc ctg ggt ctg tcc aat att tcc ttc ggc ctg aac 1843 Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile Ser Phe Gly Leu Asn 570 575 580 cct gct gca cgc cag gtt ctt aac tct gtg ttc ctc aat gag tgc att 1891 Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe Leu Asn Glu Cys Ile 585 590 595 gag gct ggt ctg gac tct gcg att gcg cac agc tcc aag att ttg ccg 1939 Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser Ser Lys Ile Leu Pro 600 605 610 atg aac cgc att gat gat cgc cag cgc gaa gtg gcg ttg gat atg gtc 1987 Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val Ala Leu Asp Met Val 615 620 625 tat gat cgc cgc acc gag gat tac gat ccg ctg cag gaa ttc atg cag 2035 Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu Gln Glu Phe Met Gln 630 635 640 645 ctg ttt gag ggc gtt tct gct gcc gat gcc aag gat gct cgc gct gaa 2083 Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys Asp Ala Arg Ala Glu 650 655 660 cag ctg gcc gct atg cct ttg ttt gag cgt ttg gca cag cgc atc atc 2131 Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu Ala Gln Arg Ile Ile 665 670 675 gac ggc gat aag aat ggc ctt gag gat gat ctg gaa gca ggc atg aag 2179 Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu Glu Ala Gly Met Lys 680 685 690 gag aag tct cct att gcg atc atc aac gag gac ctt ctc aac ggc atg 2227 Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp Leu Leu Asn Gly Met 695 700 705 aag acc gtg ggt gag ctg ttt ggt tcc gga cag atg cag ctg cca ttc 2275 Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln Met Gln Leu Pro Phe 710 715 720 725 gtg ctg caa tcg gca gaa acc atg aaa act gcg gtg gcc tat ttg gaa 2323 Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala Val Ala Tyr Leu Glu 730 735 740 ccg ttc atg gaa gag gaa gca gaa gct acc gga tct gcg cag gca gag 2371 Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly Ser Ala Gln Ala Glu 745 750 755 ggc aag ggc aaa atc gtc gtg gcc acc gtc aag ggt gac gtg cac gat 2419 Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys Gly Asp Val His Asp 760 765 770 atc ggc aag aac ttg gtg gac atc att ttg tcc aac aac ggt tac gac 2467 Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser Asn Asn Gly Tyr Asp 775 780 785 gtg gtg aac ttg ggc atc aag cag cca ctg tcc gcc atg ttg gaa gca 2515 Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser Ala Met Leu Glu Ala 790 795 800 805 gcg gaa gaa cac aaa gca gac gtc atc ggc atg tcg gga ctt ctt gtg 2563 Ala Glu Glu His Lys Ala Asp Val Ile Gly Met Ser Gly Leu Leu Val 810 815 820 aag tcc acc gtg gtg 2578 Lys Ser Thr Val Val 825 <210> 712 <211> 826 <212> PRT <213> Corynebacterium glutamicum <400> 712 Met Ser Thr Ser Val Thr Ser Pro Ala His Asn Asn Ala His Ser Ser 1 5 10 15 Glu Phe Leu Asp Ala Leu Ala Asn His Val Leu Ile Gly Asp Gly Ala 20 25 30 Met Gly Thr Gln Leu Gln Gly Phe Asp Leu Asp Val Glu Lys Asp Phe 35 40 45 Leu Asp Leu Glu Gly Cys Asn Glu Ile Leu Asn Asp Thr Arg Pro Asp 50 55 60 Val Leu Arg Gln Ile His Arg Ala Tyr Phe Glu Ala Gly Ala Asp Leu 65 70 75 80 Val Glu Thr Asn Thr Phe Gly Cys Asn Leu Pro Asn Leu Ala Asp Tyr 85 90 95 Asp Ile Ala Asp Arg Cys Arg Glu Leu Ala Tyr Lys Gly Thr Ala Val 100 105 110 Ala Arg Glu Val Ala Asp Glu Met Gly Pro Gly Arg Asn Gly Met Arg 115 120 125 Arg Phe Val Val Gly Ser Leu Gly Pro Gly Thr Lys Leu Pro Ser Leu 130 135 140 Gly His Ala Pro Tyr Ala Asp Leu Arg Gly His Tyr Lys Glu Ala Ala 145 150 155 160 Leu Gly Ile Ile Asp Gly Gly Gly Asp Ala Phe Leu Ile Glu Thr Ala 165 170 175 Gln Asp Leu Leu Gln Val Lys Ala Ala Val His Gly Val Gln Asp Ala 180 185 190 Met Ala Glu Leu Asp Thr Phe Leu Pro Ile Ile Cys His Val Thr Val 195 200 205 Glu Thr Thr Gly Thr Met Leu Met Gly Ser Glu Ile Gly Ala Ala Leu 210 215 220 Thr Ala Leu Gln Pro Leu Gly Ile Asp Met Ile Gly Leu Asn Cys Ala 225 230 235 240 Thr Gly Pro Asp Glu Met Ser Glu His Leu Arg Tyr Leu Ser Lys His 245 250 255 Ala Asp Ile Pro Val Ser Val Met Pro Asn Ala Gly Leu Pro Val Leu 260 265 270 Gly Lys Asn Gly Ala Glu Tyr Pro Leu Glu Ala Glu Asp Leu Ala Gln 275 280 285 Ala Leu Ala Gly Phe Val Ser Glu Tyr Gly Leu Ser Met Val Gly Gly 290 295 300 Cys Cys Gly Thr Thr Pro Glu His Ile Arg Ala Val Arg Asp Ala Val 305 310 315 320 Val Gly Val Pro Glu Gln Glu Thr Ser Thr Leu Thr Lys Ile Pro Ala 325 330 335 Gly Pro Val Glu Gln Ala Ser Arg Glu Val Glu Lys Glu Asp Ser Val 340 345 350 Ala Ser Leu Tyr Thr Ser Val Pro Leu Ser Gln Glu Thr Gly Ile Ser 355 360 365 Met Ile Gly Glu Arg Thr Asn Ser Asn Gly Ser Lys Ala Phe Arg Glu 370 375 380 Ala Met Leu Ser Gly Asp Trp Glu Lys Cys Val Asp Ile Ala Lys Gln 385 390 395 400 Gln Thr Arg Asp Gly Ala His Met Leu Asp Leu Cys Val Asp Tyr Val 405 410 415 Gly Arg Asp Gly Thr Ala Asp Met Ala Thr Leu Ala Ala Leu Leu Ala 420 425 430 Thr Ser Ser Thr Leu Pro Ile Met Ile Asp Ser Thr Glu Pro Glu Val 435 440 445 Ile Arg Thr Gly Leu Glu His Leu Gly Gly Arg Ser Ile Val Asn Ser 450 455 460 Val Asn Phe Glu Asp Gly Asp Gly Pro Glu Ser Arg Tyr Gln Arg Ile 465 470 475 480 Met Lys Leu Val Lys Gln His Gly Ala Ala Val Val Ala Leu Thr Ile 485 490 495 Asp Glu Glu Gly Gln Ala Arg Thr Ala Glu His Lys Val Arg Ile Ala 500 505 510 Lys Arg Leu Ile Asp Asp Ile Thr Gly Ser Tyr Gly Leu Asp Ile Lys 515 520 525 Asp Ile Val Val Asp Cys Leu Thr Phe Pro Ile Ser Thr Gly Gln Glu 530 535 540 Glu Thr Arg Arg Asp Gly Ile Glu Thr Ile Glu Ala Ile Arg Glu Leu 545 550 555 560 Lys Lys Leu Tyr Pro Glu Ile His Thr Thr Leu Gly Leu Ser Asn Ile 565 570 575 Ser Phe Gly Leu Asn Pro Ala Ala Arg Gln Val Leu Asn Ser Val Phe 580 585 590 Leu Asn Glu Cys Ile Glu Ala Gly Leu Asp Ser Ala Ile Ala His Ser 595 600 605 Ser Lys Ile Leu Pro Met Asn Arg Ile Asp Asp Arg Gln Arg Glu Val 610 615 620 Ala Leu Asp Met Val Tyr Asp Arg Arg Thr Glu Asp Tyr Asp Pro Leu 625 630 635 640 Gln Glu Phe Met Gln Leu Phe Glu Gly Val Ser Ala Ala Asp Ala Lys 645 650 655 Asp Ala Arg Ala Glu Gln Leu Ala Ala Met Pro Leu Phe Glu Arg Leu 660 665 670 Ala Gln Arg Ile Ile Asp Gly Asp Lys Asn Gly Leu Glu Asp Asp Leu 675 680 685 Glu Ala Gly Met Lys Glu Lys Ser Pro Ile Ala Ile Ile Asn Glu Asp 690 695 700 Leu Leu Asn Gly Met Lys Thr Val Gly Glu Leu Phe Gly Ser Gly Gln 705 710 715 720 Met Gln Leu Pro Phe Val Leu Gln Ser Ala Glu Thr Met Lys Thr Ala 725 730 735 Val Ala Tyr Leu Glu Pro Phe Met Glu Glu Glu Ala Glu Ala Thr Gly 740 745 750 Ser Ala Gln Ala Glu Gly Lys Gly Lys Ile Val Val Ala Thr Val Lys 755 760 765 Gly Asp Val His Asp Ile Gly Lys Asn Leu Val Asp Ile Ile Leu Ser 770 775 780 Asn Asn Gly Tyr Asp Val Val Asn Leu Gly Ile Lys Gln Pro Leu Ser 785 790 795 800 Ala Met Leu Glu Ala Ala Glu Glu His Lys Ala Asp Val Ile Gly Met 805 810 815 Ser Gly Leu Leu Val Lys Ser Thr Val Val 820 825 <210> 713 <211> 2358 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2335) <223> RXN02085 <400> 713 cacccggtga tttcgcgaac cttgaaacat cgtcagaaga ttgccgtgcg tcctagccgg 60 gatccgcacg ttcggctcaa gcagaaagtc tttaactcac atg act tcc aac ttt 115 Met Thr Ser Asn Phe 1 5 tct tcc act gtc gct ggt ctt cct cgc atc gga gcg aag cgt gaa ctg 163 Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly Ala Lys Arg Glu Leu 10 15 20 aag ttc gcg ctc gaa ggc tac tgg aat gga tca att gaa ggt cgc gaa 211 Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser Ile Glu Gly Arg Glu 25 30 35 ctt gcg cag acc gcc cgc caa ttg gtc aac act gca tcg gat tct ttg 259 Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr Ala Ser Asp Ser Leu 40 45 50 tct gga ttg gat tcc gtt ccg ttt gca gga cgt tcc tac tac gac gca 307 Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg Ser Tyr Tyr Asp Ala 55 60 65 atg ctc gat acc gcc gct att ttg ggt gtg ctg ccg gag cgt ttt gat 355 Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu Pro Glu Arg Phe Asp 70 75 80 85 gac atc gct gat cat gaa aac gat ggt ctc cca ctg tgg att gac cgc 403 Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro Leu Trp Ile Asp Arg 90 95 100 tac ttt ggc gct gct cgc ggt act gag acc ctg cct gca cag gca atg 451 Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu Pro Ala Gln Ala Met 105 110 115 acc aag tgg ttt gat acc aac tac cac tac ctc gtg ccg gag ttg tct 499 Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu Val Pro Glu Leu Ser 120 125 130 gcg gat aca cgt ttc gtt ttg gat gcg tcc gcg ctg att gag gat ctc 547 Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala Leu Ile Glu Asp Leu 135 140 145 cgt tgc cag cag gtt cgt ggc gtt aat gcc cgc cct gtt ctg gtt ggt 595 Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg Pro Val Leu Val Gly 150 155 160 165 cca ctg act ttc ctt tcc ctt gct cgc acc act gat ggt tcc aat cct 643 Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr Asp Gly Ser Asn Pro 170 175 180 ttg gat cac ctg cct gca ctg ttt gag gtc tac gag cgc ctc atc aag 691 Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr Glu Arg Leu Ile Lys 185 190 195 tct ttc gat act gag tgg gtt cag atc gat gag cct gcg ttg gtc acc 739 Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu Pro Ala Leu Val Thr 200 205 210 gat gtt gct cct gag gtt ttg gag cag gtc cgc gct ggt tac acc act 787 Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg Ala Gly Tyr Thr Thr 215 220 225 ttg gct aag cgc gat ggc gtg ttt gtc aat act tac ttc ggc tct ggc 835 Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr Tyr Phe Gly Ser Gly 230 235 240 245 gat cag gcg ctg aac act ctt gcg ggc atc ggc ctt ggc gcg att ggc 883 Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly Leu Gly Ala Ile Gly 250 255 260 gtt gac ttg gtc acc cat ggc gtc act gag ctt gct gcg tgg aag ggt 931 Val Asp Leu Val Thr His Gly Val Thr Glu Leu Ala Ala Trp Lys Gly 265 270 275 gag gag ctg ctg gtt gcg ggc atc gtt gat ggt cgt aac att tgg cgc 979 Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly Arg Asn Ile Trp Arg 280 285 290 acc gac ctg tgt gct gct ctt gct tcc ctg aag cgc ctg gca gct cgc 1027 Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys Arg Leu Ala Ala Arg 295 300 305 ggc cca atc gca gtg tct acc tct tgt tca ctg ctg cac gtt cct tac 1075 Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu Leu His Val Pro Tyr 310 315 320 325 acc ctc gag gct gag aac att gag cct gag gtc cgc gac tgg ctt gcc 1123 Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val Arg Asp Trp Leu Ala 330 335 340 ttc ggc tcg gag aag atc acc gag gtc aag ctg ctt gcc gac gcc cta 1171 Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu Leu Ala Asp Ala Leu 345 350 355 gcc ggc aac atc gac gcg gct gcg ttc gat gcg gcg tcc gca gca att 1219 Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala Ala Ser Ala Ala Ile 360 365 370 gct tct cga cgc acc tcc cca cgc acc gca cca atc acg cag gaa ctc 1267 Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro Ile Thr Gln Glu Leu 375 380 385 cct ggc cgt agc cgt gga tcc ttc gac act cgt gtt acg ctg cag gag 1315 Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg Val Thr Leu Gln Glu 390 395 400 405 aag tca ctg gag ctt cca gct ctg cca acc acc acc att ggt tct ttc 1363 Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr Thr Ile Gly Ser Phe 410 415 420 cca cag acc cca tcc att cgt tct gct cgc gct cgt ctg cgc aag gaa 1411 Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala Arg Leu Arg Lys Glu 425 430 435 tcc atc act ttg gag cag tac gaa gag gca atg cgc gaa gaa atc gat 1459 Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met Arg Glu Glu Ile Asp 440 445 450 ctg gtc atc gcc aag cag gaa gaa ctt ggt ctt gat gtg ttg gtt cac 1507 Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu Asp Val Leu Val His 455 460 465 ggt gag cca gag cgc aac gac atg gtt cag tac ttc tct gaa ctt ctc 1555 Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr Phe Ser Glu Leu Leu 470 475 480 485 gac ggt ttc ctc tca acc gcc aac ggc tgg gtc caa agc tac ggc tcc 1603 Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val Gln Ser Tyr Gly Ser 490 495 500 cgc tgt gtt cgt cct cca gtg ttg ttc gga aac gtt tcc cgc cca gcg 1651 Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn Val Ser Arg Pro Ala 505 510 515 cca atg act gtc aag tgg ttc cag tac gca cag agc ctg acc cag aag 1699 Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln Ser Leu Thr Gln Lys 520 525 530 cat gtc aag gga atg ctc acc ggt cca gtc acc atc ctt gca tgg tcc 1747 His Val Lys Gly Met Leu Thr Gly Pro Val Thr Ile Leu Ala Trp Ser 535 540 545 ttc gtt cgc gat gat cag ccg ctg gct acc act gct gac cag gtt gca 1795 Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr Ala Asp Gln Val Ala 550 555 560 565 ctg gca ctg cgc gat gaa att aac gat ctc atc gag gct ggc gcg aag 1843 Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile Glu Ala Gly Ala Lys 570 575 580 atc atc cag gtg gat gag cct gcg att cgt gaa ctg ttg ccg cta cga 1891 Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu Leu Leu Pro Leu Arg 585 590 595 gac gtc gat aag cct gcc tac ctg cag tgg tcc gtg gac tcc ttc cgc 1939 Asp Val Asp Lys Pro Ala Tyr Leu Gln Trp Ser Val Asp Ser Phe Arg 600 605 610 ctg gcg act gcc ggc gca ccc gac gac gtc caa atc cac acc cac atg 1987 Leu Ala Thr Ala Gly Ala Pro Asp Asp Val Gln Ile His Thr His Met 615 620 625 tgc tac tcc gag ttc aac gaa gtg atc tcc tcg gtc atc gcg ttg gat 2035 Cys Tyr Ser Glu Phe Asn Glu Val Ile Ser Ser Val Ile Ala Leu Asp 630 635 640 645 gcc gat gtc acc acc atc gaa gca gca cgt tcc gac atg cag gtc ctc 2083 Ala Asp Val Thr Thr Ile Glu Ala Ala Arg Ser Asp Met Gln Val Leu 650 655 660 gct gct ctg aaa tct tcc ggc ttc gag ctc ggc gtc gga cct ggt gtg 2131 Ala Ala Leu Lys Ser Ser Gly Phe Glu Leu Gly Val Gly Pro Gly Val 665 670 675 tgg gat atc cac tcc ccg cgc gtt cct tcc gcg cag aaa gtg gac ggt 2179 Trp Asp Ile His Ser Pro Arg Val Pro Ser Ala Gln Lys Val Asp Gly 680 685 690 ctc ctc gag gct gca ctg cag tcc gtg gat cct cgc cag ctg tgg gtc 2227 Leu Leu Glu Ala Ala Leu Gln Ser Val Asp Pro Arg Gln Leu Trp Val 695 700 705 aac cca gac tgt ggt ctg aag acc cgt gga tgg cca gaa gtg gaa gct 2275 Asn Pro Asp Cys Gly Leu Lys Thr Arg Gly Trp Pro Glu Val Glu Ala 710 715 720 725 tcc cta aag gtt ctc gtt gag tcc gct aag cag gct cgt gag aaa atc 2323 Ser Leu Lys Val Leu Val Glu Ser Ala Lys Gln Ala Arg Glu Lys Ile 730 735 740 gga gca act atc taaattgggt taccgctagg aac 2358 Gly Ala Thr Ile 745 <210> 714 <211> 745 <212> PRT <213> Corynebacterium glutamicum <400> 714 Met Thr Ser Asn Phe Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly 1 5 10 15 Ala Lys Arg Glu Leu Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser 20 25 30 Ile Glu Gly Arg Glu Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr 35 40 45 Ala Ser Asp Ser Leu Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg 50 55 60 Ser Tyr Tyr Asp Ala Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu 65 70 75 80 Pro Glu Arg Phe Asp Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro 85 90 95 Leu Trp Ile Asp Arg Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu 100 105 110 Pro Ala Gln Ala Met Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu 115 120 125 Val Pro Glu Leu Ser Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala 130 135 140 Leu Ile Glu Asp Leu Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg 145 150 155 160 Pro Val Leu Val Gly Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr 165 170 175 Asp Gly Ser Asn Pro Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr 180 185 190 Glu Arg Leu Ile Lys Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu 195 200 205 Pro Ala Leu Val Thr Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg 210 215 220 Ala Gly Tyr Thr Thr Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr 225 230 235 240 Tyr Phe Gly Ser Gly Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly 245 250 255 Leu Gly Ala Ile Gly Val Asp Leu Val Thr His Gly Val Thr Glu Leu 260 265 270 Ala Ala Trp Lys Gly Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly 275 280 285 Arg Asn Ile Trp Arg Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys 290 295 300 Arg Leu Ala Ala Arg Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu 305 310 315 320 Leu His Val Pro Tyr Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val 325 330 335 Arg Asp Trp Leu Ala Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu 340 345 350 Leu Ala Asp Ala Leu Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala 355 360 365 Ala Ser Ala Ala Ile Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro 370 375 380 Ile Thr Gln Glu Leu Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg 385 390 395 400 Val Thr Leu Gln Glu Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr 405 410 415 Thr Ile Gly Ser Phe Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala 420 425 430 Arg Leu Arg Lys Glu Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met 435 440 445 Arg Glu Glu Ile Asp Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu 450 455 460 Asp Val Leu Val His Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr 465 470 475 480 Phe Ser Glu Leu Leu Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val 485 490 495 Gln Ser Tyr Gly Ser Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn 500 505 510 Val Ser Arg Pro Ala Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln 515 520 525 Ser Leu Thr Gln Lys His Val Lys Gly Met Leu Thr Gly Pro Val Thr 530 535 540 Ile Leu Ala Trp Ser Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr 545 550 555 560 Ala Asp Gln Val Ala Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile 565 570 575 Glu Ala Gly Ala Lys Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu 580 585 590 Leu Leu Pro Leu Arg Asp Val Asp Lys Pro Ala Tyr Leu Gln Trp Ser 595 600 605 Val Asp Ser Phe Arg Leu Ala Thr Ala Gly Ala Pro Asp Asp Val Gln 610 615 620 Ile His Thr His Met Cys Tyr Ser Glu Phe Asn Glu Val Ile Ser Ser 625 630 635 640 Val Ile Ala Leu Asp Ala Asp Val Thr Thr Ile Glu Ala Ala Arg Ser 645 650 655 Asp Met Gln Val Leu Ala Ala Leu Lys Ser Ser Gly Phe Glu Leu Gly 660 665 670 Val Gly Pro Gly Val Trp Asp Ile His Ser Pro Arg Val Pro Ser Ala 675 680 685 Gln Lys Val Asp Gly Leu Leu Glu Ala Ala Leu Gln Ser Val Asp Pro 690 695 700 Arg Gln Leu Trp Val Asn Pro Asp Cys Gly Leu Lys Thr Arg Gly Trp 705 710 715 720 Pro Glu Val Glu Ala Ser Leu Lys Val Leu Val Glu Ser Ala Lys Gln 725 730 735 Ala Arg Glu Lys Ile Gly Ala Thr Ile 740 745 <210> 715 <211> 1923 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1900) <223> FRXA02085 <400> 715 cacccggtga tttcgcgaac cttgaaacat cgtcagaaga ttgccgtgcg tcctagccgg 60 gatccgcacg ttcggctcaa gcagaaagtc tttaactcac atg act tcc aac ttt 115 Met Thr Ser Asn Phe 1 5 tct tcc act gtc gct ggt ctt cct cgc atc gga gcg aag cgt gaa ctg 163 Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly Ala Lys Arg Glu Leu 10 15 20 aag ttc gcg ctc gaa ggc tac tgg aat gga tca att gaa ggt cgc gaa 211 Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser Ile Glu Gly Arg Glu 25 30 35 ctt gcg cag acc gcc cgc caa ttg gtc aac act gca tcg gat tct ttg 259 Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr Ala Ser Asp Ser Leu 40 45 50 tct gga ttg gat tcc gtt ccg ttt gca gga cgt tcc tac tac gac gca 307 Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg Ser Tyr Tyr Asp Ala 55 60 65 atg ctc gat acc gcc gct att ttg ggt gtg ctg ccg gag cgt ttt gat 355 Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu Pro Glu Arg Phe Asp 70 75 80 85 gac atc gct gat cat gaa aac gat ggt ctc cca ctg tgg att gac cgc 403 Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro Leu Trp Ile Asp Arg 90 95 100 tac ttt ggc gct gct cgc ggt act gag acc ctg cct gca cag gca atg 451 Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu Pro Ala Gln Ala Met 105 110 115 acc aag tgg ttt gat acc aac tac cac tac ctc gtg ccg gag ttg tct 499 Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu Val Pro Glu Leu Ser 120 125 130 gcg gat aca cgt ttc gtt ttg gat gcg tcc gcg ctg att gag gat ctc 547 Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala Leu Ile Glu Asp Leu 135 140 145 cgt tgc cag cag gtt cgt ggc gtt aat gcc cgc cct gtt ctg gtt ggt 595 Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg Pro Val Leu Val Gly 150 155 160 165 cca ctg act ttc ctt tcc ctt gct cgc acc act gat ggt tcc aat cct 643 Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr Asp Gly Ser Asn Pro 170 175 180 ttg gat cac ctg cct gca ctg ttt gag gtc tac gag cgc ctc atc aag 691 Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr Glu Arg Leu Ile Lys 185 190 195 tct ttc gat act gag tgg gtt cag atc gat gag cct gcg ttg gtc acc 739 Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu Pro Ala Leu Val Thr 200 205 210 gat gtt gct cct gag gtt ttg gag cag gtc cgc gct ggt tac acc act 787 Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg Ala Gly Tyr Thr Thr 215 220 225 ttg gct aag cgc gat ggc gtg ttt gtc aat act tac ttc ggc tct ggc 835 Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr Tyr Phe Gly Ser Gly 230 235 240 245 gat cag gcg ctg aac act ctt gcg ggc atc ggc ctt ggc gcg att ggc 883 Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly Leu Gly Ala Ile Gly 250 255 260 gtt gac ttg gtc acc cat ggc gtc act gag ctt gct gcg tgg aag ggt 931 Val Asp Leu Val Thr His Gly Val Thr Glu Leu Ala Ala Trp Lys Gly 265 270 275 gag gag ctg ctg gtt gcg ggc atc gtt gat ggt cgt aac att tgg cgc 979 Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly Arg Asn Ile Trp Arg 280 285 290 acc gac ctg tgt gct gct ctt gct tcc ctg aag cgc ctg gca gct cgc 1027 Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys Arg Leu Ala Ala Arg 295 300 305 ggc cca atc gca gtg tct acc tct tgt tca ctg ctg cac gtt cct tac 1075 Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu Leu His Val Pro Tyr 310 315 320 325 acc ctc gag gct gag aac att gag cct gag gtc cgc gac tgg ctt gcc 1123 Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val Arg Asp Trp Leu Ala 330 335 340 ttc ggc tcg gag aag atc acc gag gtc aag ctg ctt gcc gac gcc cta 1171 Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu Leu Ala Asp Ala Leu 345 350 355 gcc ggc aac atc gac gcg gct gcg ttc gat gcg gcg tcc gca gca att 1219 Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala Ala Ser Ala Ala Ile 360 365 370 gct tct cga cgc acc tcc cca cgc acc gca cca atc acg cag gaa ctc 1267 Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro Ile Thr Gln Glu Leu 375 380 385 cct ggc cgt agc cgt gga tcc ttc gac act cgt gtt acg ctg cag gag 1315 Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg Val Thr Leu Gln Glu 390 395 400 405 aag tca ctg gag ctt cca gct ctg cca acc acc acc att ggt tct ttc 1363 Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr Thr Ile Gly Ser Phe 410 415 420 cca cag acc cca tcc att cgt tct gct cgc gct cgt ctg cgc aag gaa 1411 Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala Arg Leu Arg Lys Glu 425 430 435 tcc atc act ttg gag cag tac gaa gag gca atg cgc gaa gaa atc gat 1459 Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met Arg Glu Glu Ile Asp 440 445 450 ctg gtc atc gcc aag cag gaa gaa ctt ggt ctt gat gtg ttg gtt cac 1507 Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu Asp Val Leu Val His 455 460 465 ggt gag cca gag cgc aac gac atg gtt cag tac ttc tct gaa ctt ctc 1555 Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr Phe Ser Glu Leu Leu 470 475 480 485 gac ggt ttc ctc tca acc gcc aac ggc tgg gtc caa agc tac ggc tcc 1603 Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val Gln Ser Tyr Gly Ser 490 495 500 cgc tgt gtt cgt cct cca gtg ttg ttc gga aac gtt tcc cgc cca gcg 1651 Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn Val Ser Arg Pro Ala 505 510 515 cca atg act gtc aag tgg ttc cag tac gca cag agc ctg acc cag aag 1699 Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln Ser Leu Thr Gln Lys 520 525 530 cat gtc aag gga atg ctc acc ggt cca gtc acc atc ctt gca tgg tcc 1747 His Val Lys Gly Met Leu Thr Gly Pro Val Thr Ile Leu Ala Trp Ser 535 540 545 ttc gtt cgc gat gat cag ccg ctg gct acc act gct gac cag gtt gca 1795 Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr Ala Asp Gln Val Ala 550 555 560 565 ctg gca ctg cgc gat gaa att aac gat ctc atc gag gct ggc gcg aag 1843 Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile Glu Ala Gly Ala Lys 570 575 580 atc atc cag gtg gat gag cct gcg att cgt gaa ctg ttg ccc gct acg 1891 Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu Leu Leu Pro Ala Thr 585 590 595 aga cgt cga taagcctgcc tacctgcagt ggt 1923 Arg Arg Arg 600 <210> 716 <211> 600 <212> PRT <213> Corynebacterium glutamicum <400> 716 Met Thr Ser Asn Phe Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly 1 5 10 15 Ala Lys Arg Glu Leu Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser 20 25 30 Ile Glu Gly Arg Glu Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr 35 40 45 Ala Ser Asp Ser Leu Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg 50 55 60 Ser Tyr Tyr Asp Ala Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu 65 70 75 80 Pro Glu Arg Phe Asp Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro 85 90 95 Leu Trp Ile Asp Arg Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu 100 105 110 Pro Ala Gln Ala Met Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu 115 120 125 Val Pro Glu Leu Ser Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala 130 135 140 Leu Ile Glu Asp Leu Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg 145 150 155 160 Pro Val Leu Val Gly Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr 165 170 175 Asp Gly Ser Asn Pro Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr 180 185 190 Glu Arg Leu Ile Lys Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu 195 200 205 Pro Ala Leu Val Thr Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg 210 215 220 Ala Gly Tyr Thr Thr Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr 225 230 235 240 Tyr Phe Gly Ser Gly Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly 245 250 255 Leu Gly Ala Ile Gly Val Asp Leu Val Thr His Gly Val Thr Glu Leu 260 265 270 Ala Ala Trp Lys Gly Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly 275 280 285 Arg Asn Ile Trp Arg Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys 290 295 300 Arg Leu Ala Ala Arg Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu 305 310 315 320 Leu His Val Pro Tyr Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val 325 330 335 Arg Asp Trp Leu Ala Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu 340 345 350 Leu Ala Asp Ala Leu Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala 355 360 365 Ala Ser Ala Ala Ile Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro 370 375 380 Ile Thr Gln Glu Leu Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg 385 390 395 400 Val Thr Leu Gln Glu Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr 405 410 415 Thr Ile Gly Ser Phe Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala 420 425 430 Arg Leu Arg Lys Glu Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met 435 440 445 Arg Glu Glu Ile Asp Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu 450 455 460 Asp Val Leu Val His Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr 465 470 475 480 Phe Ser Glu Leu Leu Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val 485 490 495 Gln Ser Tyr Gly Ser Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn 500 505 510 Val Ser Arg Pro Ala Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln 515 520 525 Ser Leu Thr Gln Lys His Val Lys Gly Met Leu Thr Gly Pro Val Thr 530 535 540 Ile Leu Ala Trp Ser Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr 545 550 555 560 Ala Asp Gln Val Ala Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile 565 570 575 Glu Ala Gly Ala Lys Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu 580 585 590 Leu Leu Pro Ala Thr Arg Arg Arg 595 600 <210> 717 <211> 603 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(580) <223> FRXA02086 <400> 717 gatgatcagc cgctggctac cactgctgac caggttgcac tggcactgcg cgatgaaatt 60 aacgatctca tcgaggctgg cgcgaagatc atccaggtgg atg agc ctg cga ttc 115 Met Ser Leu Arg Phe 1 5 gtg aac tgt tgc ccg cta cga gac gtc gat aag cct gcc tac ctg cag 163 Val Asn Cys Cys Pro Leu Arg Asp Val Asp Lys Pro Ala Tyr Leu Gln 10 15 20 tgg tcc gtg gac tcc ttc cgc ctg gcg act gcc ggc gca ccc gac gac 211 Trp Ser Val Asp Ser Phe Arg Leu Ala Thr Ala Gly Ala Pro Asp Asp 25 30 35 gtc caa atc cac acc cac atg tgc tac tcc gag ttc aac gaa gtg atc 259 Val Gln Ile His Thr His Met Cys Tyr Ser Glu Phe Asn Glu Val Ile 40 45 50 tcc tcg gtc atc gcg ttg gat gcc gat gtc acc acc atc gaa gca gca 307 Ser Ser Val Ile Ala Leu Asp Ala Asp Val Thr Thr Ile Glu Ala Ala 55 60 65 cgt tcc gac atg cag gtc ctc gct gct ctg aaa tct tcc ggc ttc gag 355 Arg Ser Asp Met Gln Val Leu Ala Ala Leu Lys Ser Ser Gly Phe Glu 70 75 80 85 ctc ggc gtc gga cct ggt gtg tgg gat atc cac tcc ccg cgc gtt cct 403 Leu Gly Val Gly Pro Gly Val Trp Asp Ile His Ser Pro Arg Val Pro 90 95 100 tcc gcg cag aaa gtg gac ggt ctc ctc gag gct gca ctg cag tcc gtg 451 Ser Ala Gln Lys Val Asp Gly Leu Leu Glu Ala Ala Leu Gln Ser Val 105 110 115 gat cct cgc cag ctg tgg gtc aac cca gac tgt ggt ctg aag acc cgt 499 Asp Pro Arg Gln Leu Trp Val Asn Pro Asp Cys Gly Leu Lys Thr Arg 120 125 130 gga tgg cca gaa gtg gaa gct tcc cta aag gtt ctc gtt gag tcc gct 547 Gly Trp Pro Glu Val Glu Ala Ser Leu Lys Val Leu Val Glu Ser Ala 135 140 145 aag cag gct cgt gag aaa atc gga gca act atc taaattgggt taccgctagg 600 Lys Gln Ala Arg Glu Lys Ile Gly Ala Thr Ile 150 155 160 aac 603 <210> 718 <211> 160 <212> PRT <213> Corynebacterium glutamicum <400> 718 Met Ser Leu Arg Phe Val Asn Cys Cys Pro Leu Arg Asp Val Asp Lys 1 5 10 15 Pro Ala Tyr Leu Gln Trp Ser Val Asp Ser Phe Arg Leu Ala Thr Ala 20 25 30 Gly Ala Pro Asp Asp Val Gln Ile His Thr His Met Cys Tyr Ser Glu 35 40 45 Phe Asn Glu Val Ile Ser Ser Val Ile Ala Leu Asp Ala Asp Val Thr 50 55 60 Thr Ile Glu Ala Ala Arg Ser Asp Met Gln Val Leu Ala Ala Leu Lys 65 70 75 80 Ser Ser Gly Phe Glu Leu Gly Val Gly Pro Gly Val Trp Asp Ile His 85 90 95 Ser Pro Arg Val Pro Ser Ala Gln Lys Val Asp Gly Leu Leu Glu Ala 100 105 110 Ala Leu Gln Ser Val Asp Pro Arg Gln Leu Trp Val Asn Pro Asp Cys 115 120 125 Gly Leu Lys Thr Arg Gly Trp Pro Glu Val Glu Ala Ser Leu Lys Val 130 135 140 Leu Val Glu Ser Ala Lys Gln Ala Arg Glu Lys Ile Gly Ala Thr Ile 145 150 155 160 <210> 719 <211> 1326 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1303) <223> RXN02648 <400> 719 atgaataaaa ttccgggtgc agtgaccgta ggtgaggtaa acgcggttag agtcgaatga 60 gagtttgata ctttctttcg acttttagat tggattttca atg agc cag aac cgc 115 Met Ser Gln Asn Arg 1 5 atc agg acc act cac gtt ggt tcc ttg ccc cgt acc cca gag cta ctt 163 Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg Thr Pro Glu Leu Leu 10 15 20 gat gca aac atc aag cgt tct aac ggt gag att ggg gag gag gaa ttc 211 Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile Gly Glu Glu Glu Phe 25 30 35 ttc cag att ctg cag tct tct gta gat gac gtg atc aag cgc cag gtt 259 Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val Ile Lys Arg Gln Val 40 45 50 gac ctg ggt atc gac atc ctt aac gag ggc gaa tac ggc cac gtc acc 307 Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu Tyr Gly His Val Thr 55 60 65 tcc ggt gca gtt gac ttc ggt gca tgg tgg aac tac tcc ttc acc cgc 355 Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn Tyr Ser Phe Thr Arg 70 75 80 85 ctg ggc gga ctg acc atg acc gat acc gac cgt tgg gca agc cag gaa 403 Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg Trp Ala Ser Gln Glu 90 95 100 gca gtg cgt tcc acc cct ggc aac atc gag ctg acc agc ttc tct gat 451 Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu Thr Ser Phe Ser Asp 105 110 115 cgt cgc gac cgc gca ttg ttc agc gaa gca tac gag gat cca gta tct 499 Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr Glu Asp Pro Val Ser 120 125 130 ggc atc ttc acc ggt cgc gct tct gtg ggc aac cca gag ttc acc gga 547 Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn Pro Glu Phe Thr Gly 135 140 145 cct att acc tac att ggc cag gaa gaa act cag acg gat gtt gat ctg 595 Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln Thr Asp Val Asp Leu 150 155 160 165 ctg aag aag ggc atg aac gca gcg gga gct acc gac ggc ttc gtt gca 643 Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr Asp Gly Phe Val Ala 170 175 180 gca cta tcc cca gga tct gca gct cga ttg acc aac aag ttc tac gac 691 Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr Asn Lys Phe Tyr Asp 185 190 195 act gat gaa gaa gtc gtc gca gca tgt gct gat gcg ctt tcc cag gaa 739 Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp Ala Leu Ser Gln Glu 200 205 210 tac aag atc atc acc gat gca ggt ctg acc gtt cag ctc gac gca ccg 787 Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val Gln Leu Asp Ala Pro 215 220 225 gac ttg gca gaa gca tgg gat cag atc aac cca gag cca agc gtg aag 835 Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro Ser Val Lys 230 235 240 245 gat tac ttg gac tgg atc ggt aca cgc atc gat gcc atc aac agt gca 883 Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile Asn Ser Ala 250 255 260 gtg aag ggc ctt cca aag gaa cag acc cgc ctg cac atc tgc tgg ggc 931 Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile Cys Trp Gly 265 270 275 tct tgg cac gga cca cac gtc act gac atc cca ttc ggt gac atc att 979 Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly Asp Ile Ile 280 285 290 ggt gag atc ctg cgc gca gag gtc ggt ggc ttc tcc ttc gaa ggc gca 1027 Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe Glu Gly Ala 295 300 305 tct cct cgt cac gca cac gag tgg cgt gta tgg gaa gaa aac aag ctt 1075 Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu Asn Lys Leu 310 315 320 325 cct gaa ggc tct gtt atc tac cct ggt gtt gtg tct cac tcc atc aac 1123 Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His Ser Ile Asn 330 335 340 gct gtg gag cac cca cgc ctg gtt gct gat cgt atc gtt cag ttc gcc 1171 Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val Gln Phe Ala 345 350 355 aag ctt gtt ggc cct gag aac gtc att gcg tcc act gac tgt ggt ctg 1219 Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp Cys Gly Leu 360 365 370 ggc gga cgt ctg cat tcc cag atc gca tgg gca aag ctg gag tcc cta 1267 Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu Glu Ser Leu 375 380 385 gta gag ggc gct cgc att gca tca aag gaa ctg ttc taagctagac 1313 Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 390 395 400 aacgagggtt gct 1326 <210> 720 <211> 401 <212> PRT <213> Corynebacterium glutamicum <400> 720 Met Ser Gln Asn Arg Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg 1 5 10 15 Thr Pro Glu Leu Leu Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile 20 25 30 Gly Glu Glu Glu Phe Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val 35 40 45 Ile Lys Arg Gln Val Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu 50 55 60 Tyr Gly His Val Thr Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn 65 70 75 80 Tyr Ser Phe Thr Arg Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg 85 90 95 Trp Ala Ser Gln Glu Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu 100 105 110 Thr Ser Phe Ser Asp Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr 115 120 125 Glu Asp Pro Val Ser Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn 130 135 140 Pro Glu Phe Thr Gly Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln 145 150 155 160 Thr Asp Val Asp Leu Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr 165 170 175 Asp Gly Phe Val Ala Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr 180 185 190 Asn Lys Phe Tyr Asp Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp 195 200 205 Ala Leu Ser Gln Glu Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val 210 215 220 Gln Leu Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro 225 230 235 240 Glu Pro Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp 245 250 255 Ala Ile Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu 260 265 270 His Ile Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro 275 280 285 Phe Gly Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe 290 295 300 Ser Phe Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp 305 310 315 320 Glu Glu Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val 325 330 335 Ser His Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg 340 345 350 Ile Val Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser 355 360 365 Thr Asp Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala 370 375 380 Lys Leu Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu 385 390 395 400 Phe <210> 721 <211> 548 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(525) <223> FRXA02648 <400> 721 gac gca ccg gac ttg gca gaa gca tgg gat cag atc aac cca gag cca 48 Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro 1 5 10 15 agc gtg aag gat tac ttg gac tgg atc ggt aca cgc atc gat gcc atc 96 Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile 20 25 30 aac agt gca gtg aag ggc ctt cca aag gaa cag acc cgc ctg cac atc 144 Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile 35 40 45 tgc tgg ggc tct tgg cac gga cca cac gtc act gac atc cca ttc ggt 192 Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly 50 55 60 gac atc att ggt gag atc ctg cgc gca gag gtc ggt ggc ttc tcc ttc 240 Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe 65 70 75 80 gaa ggc gca tct cct cgt cac gca cac gag tgg cgt gta tgg gaa gaa 288 Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu 85 90 95 aac aag ctt cct gaa ggc tct gtt atc tac cct ggt gtt gtg tct cac 336 Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His 100 105 110 tcc atc aac gct gtg gag cac cca cgc ctg gtt gct gat cgt atc gtt 384 Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val 115 120 125 cag ttc gcc aag ctt gtt ggc cct gag aac gtc att gcg tcc act gac 432 Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp 130 135 140 tgt ggt ctg ggc gga cgt ctg cat tcc cag atc gca tgg gca aag ctg 480 Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu 145 150 155 160 gag tcc cta gta gag ggc gct cgc att gca tca aag gaa ctg ttc 525 Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 165 170 175 taagctagac aacgagggtt gct 548 <210> 722 <211> 175 <212> PRT <213> Corynebacterium glutamicum <400> 722 Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro 1 5 10 15 Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile 20 25 30 Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile 35 40 45 Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly 50 55 60 Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe 65 70 75 80 Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu 85 90 95 Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His 100 105 110 Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val 115 120 125 Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp 130 135 140 Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu 145 150 155 160 Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 165 170 175 <210> 723 <211> 784 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(784) <223> FRXA02658 <400> 723 atgaataaaa ttccgggtgc agtgaccgta ggtgaggtaa acgcggttag agtcgaatga 60 gagtttgata ctttctttcg acttttagat tggattttca atg agc cag aac cgc 115 Met Ser Gln Asn Arg 1 5 atc agg acc act cac gtt ggt tcc ttg ccc cgt acc cca gag cta ctt 163 Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg Thr Pro Glu Leu Leu 10 15 20 gat gca aac atc aag cgt tct aac ggt gag att ggg gag gag gaa ttc 211 Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile Gly Glu Glu Glu Phe 25 30 35 ttc cag att ctg cag tct tct gta gat gac gtg atc aag cgc cag gtt 259 Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val Ile Lys Arg Gln Val 40 45 50 gac ctg ggt atc gac atc ctt aac gag ggc gaa tac ggc cac gtc acc 307 Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu Tyr Gly His Val Thr 55 60 65 tcc ggt gca gtt gac ttc ggt gca tgg tgg aac tac tcc ttc acc cgc 355 Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn Tyr Ser Phe Thr Arg 70 75 80 85 ctg ggc gga ctg acc atg acc gat acc gac cgt tgg gca agc cag gaa 403 Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg Trp Ala Ser Gln Glu 90 95 100 gca gtg cgt tcc acc cct ggc aac atc gag ctg acc agc ttc tct gat 451 Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu Thr Ser Phe Ser Asp 105 110 115 cgt cgc gac cgc gca ttg ttc agc gaa gca tac gag gat cca gta tct 499 Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr Glu Asp Pro Val Ser 120 125 130 ggc atc ttc acc ggt cgc gct tct gtg ggc aac cca gag ttc acc gga 547 Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn Pro Glu Phe Thr Gly 135 140 145 cct att acc tac att ggc cag gaa gaa act cag acg gat gtt gat ctg 595 Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln Thr Asp Val Asp Leu 150 155 160 165 ctg aag aag ggc atg aac gca gcg gga gct acc gac ggc ttc gtt gca 643 Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr Asp Gly Phe Val Ala 170 175 180 gca cta tcc cca gga tct gca gct cga ttg acc aac aag ttc tac gac 691 Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr Asn Lys Phe Tyr Asp 185 190 195 act gat gaa gaa gtc gtc gca gca tgt gct gat gcg ctt tcc cag gaa 739 Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp Ala Leu Ser Gln Glu 200 205 210 tac aag atc atc acc gat gca ggt ctg acc gtt cag ctc gac gca 784 Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val Gln Leu Asp Ala 215 220 225 <210> 724 <211> 228 <212> PRT <213> Corynebacterium glutamicum <400> 724 Met Ser Gln Asn Arg Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg 1 5 10 15 Thr Pro Glu Leu Leu Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile 20 25 30 Gly Glu Glu Glu Phe Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val 35 40 45 Ile Lys Arg Gln Val Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu 50 55 60 Tyr Gly His Val Thr Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn 65 70 75 80 Tyr Ser Phe Thr Arg Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg 85 90 95 Trp Ala Ser Gln Glu Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu 100 105 110 Thr Ser Phe Ser Asp Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr 115 120 125 Glu Asp Pro Val Ser Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn 130 135 140 Pro Glu Phe Thr Gly Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln 145 150 155 160 Thr Asp Val Asp Leu Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr 165 170 175 Asp Gly Phe Val Ala Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr 180 185 190 Asn Lys Phe Tyr Asp Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp 195 200 205 Ala Leu Ser Gln Glu Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val 210 215 220 Gln Leu Asp Ala 225 <210> 725 <211> 551 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(528) <223> RXS02197 <400> 725 gcc gaa cgc atg cgc ttt agc ttc cca cgc cag cag cgc ggc agg ttc 48 Ala Glu Arg Met Arg Phe Ser Phe Pro Arg Gln Gln Arg Gly Arg Phe 1 5 10 15 ttg tgc atc gcg gat ttc att cgc cca cgc gag caa gct gtc aag gac 96 Leu Cys Ile Ala Asp Phe Ile Arg Pro Arg Glu Gln Ala Val Lys Asp 20 25 30 ggc caa gtg gac gtc atg cca ttc cag ctg gtc acc atg ggt aat cct 144 Gly Gln Val Asp Val Met Pro Phe Gln Leu Val Thr Met Gly Asn Pro 35 40 45 att gct gat ttc gcc aac gag ttg ttc gca gcc aat gaa tac cgc gag 192 Ile Ala Asp Phe Ala Asn Glu Leu Phe Ala Ala Asn Glu Tyr Arg Glu 50 55 60 tac ttg gaa gtt cac ggc atc ggc gtg cag ctc acc gaa gca ttg gcc 240 Tyr Leu Glu Val His Gly Ile Gly Val Gln Leu Thr Glu Ala Leu Ala 65 70 75 80 gag tac tgg cac tcc cga gtg cgc agc gaa ctc aag ctg aac gac ggt 288 Glu Tyr Trp His Ser Arg Val Arg Ser Glu Leu Lys Leu Asn Asp Gly 85 90 95 gga tct gtc gct gat ttt gat cca gaa gac aag acc aag ttc ttc gac 336 Gly Ser Val Ala Asp Phe Asp Pro Glu Asp Lys Thr Lys Phe Phe Asp 100 105 110 ctg gat tac cgc ggc gcc cgc ttc tcc ttt ggt tac ggt tct tgc cct 384 Leu Asp Tyr Arg Gly Ala Arg Phe Ser Phe Gly Tyr Gly Ser Cys Pro 115 120 125 gat ctg gaa gac cgc gca aag ctg gtg gaa ttg ctc gag cca ggc cgt 432 Asp Leu Glu Asp Arg Ala Lys Leu Val Glu Leu Leu Glu Pro Gly Arg 130 135 140 atc ggc gtg gag ttg tcc gag gaa ctc cag ctg cac cca gag cag tcc 480 Ile Gly Val Glu Leu Ser Glu Glu Leu Gln Leu His Pro Glu Gln Ser 145 150 155 160 aca gac gcg ttt gtg ctc tac cac cca gag gca aag tac ttt aac gtc 528 Thr Asp Ala Phe Val Leu Tyr His Pro Glu Ala Lys Tyr Phe Asn Val 165 170 175 taacaccttt gagagggaaa act 551 <210> 726 <211> 176 <212> PRT <213> Corynebacterium glutamicum <400> 726 Ala Glu Arg Met Arg Phe Ser Phe Pro Arg Gln Gln Arg Gly Arg Phe 1 5 10 15 Leu Cys Ile Ala Asp Phe Ile Arg Pro Arg Glu Gln Ala Val Lys Asp 20 25 30 Gly Gln Val Asp Val Met Pro Phe Gln Leu Val Thr Met Gly Asn Pro 35 40 45 Ile Ala Asp Phe Ala Asn Glu Leu Phe Ala Ala Asn Glu Tyr Arg Glu 50 55 60 Tyr Leu Glu Val His Gly Ile Gly Val Gln Leu Thr Glu Ala Leu Ala 65 70 75 80 Glu Tyr Trp His Ser Arg Val Arg Ser Glu Leu Lys Leu Asn Asp Gly 85 90 95 Gly Ser Val Ala Asp Phe Asp Pro Glu Asp Lys Thr Lys Phe Phe Asp 100 105 110 Leu Asp Tyr Arg Gly Ala Arg Phe Ser Phe Gly Tyr Gly Ser Cys Pro 115 120 125 Asp Leu Glu Asp Arg Ala Lys Leu Val Glu Leu Leu Glu Pro Gly Arg 130 135 140 Ile Gly Val Glu Leu Ser Glu Glu Leu Gln Leu His Pro Glu Gln Ser 145 150 155 160 Thr Asp Ala Phe Val Leu Tyr His Pro Glu Ala Lys Tyr Phe Asn Val 165 170 175 <210> 727 <211> 546 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(523) <223> RXC00988 <400> 727 tagcagaaga caccgatgta cagtccggat caggtgttgt gatcaccggt tcaatcgtga 60 ccgccggcga tgcgcgcacg ctgtttggaa aggaacctgc atg agc aag cgt gaa 115 Met Ser Lys Arg Glu 1 5 gaa tca att gag tac gga cca tta ggc aaa ggc cac gat cca tta aag 163 Glu Ser Ile Glu Tyr Gly Pro Leu Gly Lys Gly His Asp Pro Leu Lys 10 15 20 gat ccc atg aag ggt atc cga ggt gtc atg gcc ggc acc tta gtg atg 211 Asp Pro Met Lys Gly Ile Arg Gly Val Met Ala Gly Thr Leu Val Met 25 30 35 gaa gca atc acc tta ggt ctt gtt ctc acc gtg att ctg cgc gtg gac 259 Glu Ala Ile Thr Leu Gly Leu Val Leu Thr Val Ile Leu Arg Val Asp 40 45 50 gac ggc atc tac tgg acc acc ttc aac tgg gtc tat gta tca gca gtc 307 Asp Gly Ile Tyr Trp Thr Thr Phe Asn Trp Val Tyr Val Ser Ala Val 55 60 65 gcg atc gca cac ttt gtt gct gca ttt ctg caa agg ttt agt tgg tcc 355 Ala Ile Ala His Phe Val Ala Ala Phe Leu Gln Arg Phe Ser Trp Ser 70 75 80 85 atc ccg atg aac atc gtg ctg cag gtt ctt gca ctt gcc ggt ttc ttt 403 Ile Pro Met Asn Ile Val Leu Gln Val Leu Ala Leu Ala Gly Phe Phe 90 95 100 gtt cac ccc gcg atg ggc ttc gcc gcc atc atc ttc atc atc gcg tgg 451 Val His Pro Ala Met Gly Phe Ala Ala Ile Ile Phe Ile Ile Ala Trp 105 110 115 gcg tac ctg ttc tac ctg cgc tct aat ctg att gat cgc atg aaa cgc 499 Ala Tyr Leu Phe Tyr Leu Arg Ser Asn Leu Ile Asp Arg Met Lys Arg 120 125 130 ggg ctg ctt acc acg cag cac agc taagctttaa ggccctccgg ggc 546 Gly Leu Leu Thr Thr Gln His Ser 135 140 <210> 728 <211> 141 <212> PRT <213> Corynebacterium glutamicum <400> 728 Met Ser Lys Arg Glu Glu Ser Ile Glu Tyr Gly Pro Leu Gly Lys Gly 1 5 10 15 His Asp Pro Leu Lys Asp Pro Met Lys Gly Ile Arg Gly Val Met Ala 20 25 30 Gly Thr Leu Val Met Glu Ala Ile Thr Leu Gly Leu Val Leu Thr Val 35 40 45 Ile Leu Arg Val Asp Asp Gly Ile Tyr Trp Thr Thr Phe Asn Trp Val 50 55 60 Tyr Val Ser Ala Val Ala Ile Ala His Phe Val Ala Ala Phe Leu Gln 65 70 75 80 Arg Phe Ser Trp Ser Ile Pro Met Asn Ile Val Leu Gln Val Leu Ala 85 90 95 Leu Ala Gly Phe Phe Val His Pro Ala Met Gly Phe Ala Ala Ile Ile 100 105 110 Phe Ile Ile Ala Trp Ala Tyr Leu Phe Tyr Leu Arg Ser Asn Leu Ile 115 120 125 Asp Arg Met Lys Arg Gly Leu Leu Thr Thr Gln His Ser 130 135 140 <210> 729 <211> 597 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(574) <223> RXC01518 <400> 729 agcagaacct gatgccgtcc tgcacggcac gaccattgca gaacatgtgg ataatcttga 60 tcccacagac attgaaggtg tcaccaagat ttaaggagtc gtg gct ttc atg cag 115 Val Ala Phe Met Gln 1 5 aaa acg tca gcg ggt tgg ttg atc gca acg gga ggt ttc ctc gcc gct 163 Lys Thr Ser Ala Gly Trp Leu Ile Ala Thr Gly Gly Phe Leu Ala Ala 10 15 20 gtg tcc gcc att ttg acg tgg cgt ttt tat gga tcc atg acc tct att 211 Val Ser Ala Ile Leu Thr Trp Arg Phe Tyr Gly Ser Met Thr Ser Ile 25 30 35 tcc atc acg gta tcc atc act ttt tgg ttg ttg gcc gtg gtg tgt ggt 259 Ser Ile Thr Val Ser Ile Thr Phe Trp Leu Leu Ala Val Val Cys Gly 40 45 50 ttc gca ggt gtg aag gtc caa ggt cgc ctc gat gag ggg ctg atc ggc 307 Phe Ala Gly Val Lys Val Gln Gly Arg Leu Asp Glu Gly Leu Ile Gly 55 60 65 cag gac aaa tcc caa atg aac ccc gtg acc att gcc tat ctg gcc atg 355 Gln Asp Lys Ser Gln Met Asn Pro Val Thr Ile Ala Tyr Leu Ala Met 70 75 80 85 ctg ggt cga gcg tgt gcg tgg ggt ggc gca att ttc ggc ggc gtt tat 403 Leu Gly Arg Ala Cys Ala Trp Gly Gly Ala Ile Phe Gly Gly Val Tyr 90 95 100 gtg gga att ggc agt tat gta atc cca cgc gcc ggt gag ttg tcc gca 451 Val Gly Ile Gly Ser Tyr Val Ile Pro Arg Ala Gly Glu Leu Ser Ala 105 110 115 gca tcg aat gat ctt ccg gga gtt att gcc tgt gcg ctg ggc gga atc 499 Ala Ser Asn Asp Leu Pro Gly Val Ile Ala Cys Ala Leu Gly Gly Ile 120 125 130 gca ctc tca gct gcc gga ctt tat tta gag cga agc tgt gag gct ccg 547 Ala Leu Ser Ala Ala Gly Leu Tyr Leu Glu Arg Ser Cys Glu Ala Pro 135 140 145 cct ccc caa tct ggc gaa gcg atc agc tagattggaa ttcatgaatc 594 Pro Pro Gln Ser Gly Glu Ala Ile Ser 150 155 aag 597 <210> 730 <211> 158 <212> PRT <213> Corynebacterium glutamicum <400> 730 Val Ala Phe Met Gln Lys Thr Ser Ala Gly Trp Leu Ile Ala Thr Gly 1 5 10 15 Gly Phe Leu Ala Ala Val Ser Ala Ile Leu Thr Trp Arg Phe Tyr Gly 20 25 30 Ser Met Thr Ser Ile Ser Ile Thr Val Ser Ile Thr Phe Trp Leu Leu 35 40 45 Ala Val Val Cys Gly Phe Ala Gly Val Lys Val Gln Gly Arg Leu Asp 50 55 60 Glu Gly Leu Ile Gly Gln Asp Lys Ser Gln Met Asn Pro Val Thr Ile 65 70 75 80 Ala Tyr Leu Ala Met Leu Gly Arg Ala Cys Ala Trp Gly Gly Ala Ile 85 90 95 Phe Gly Gly Val Tyr Val Gly Ile Gly Ser Tyr Val Ile Pro Arg Ala 100 105 110 Gly Glu Leu Ser Ala Ala Ser Asn Asp Leu Pro Gly Val Ile Ala Cys 115 120 125 Ala Leu Gly Gly Ile Ala Leu Ser Ala Ala Gly Leu Tyr Leu Glu Arg 130 135 140 Ser Cys Glu Ala Pro Pro Pro Gln Ser Gly Glu Ala Ile Ser 145 150 155 <210> 731 <211> 723 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(700) <223> RXC01942 <400> 731 gccgcgaaat tcggtgaaat tgaaggtatt cctgcagatc aggcaaattc ttccacgact 60 gtgatcaagg tcaacggcaa gaacgagtaa cctgggatcc atg ttg cgc att gga 115 Met Leu Arg Ile Gly 1 5 cta aca gga ggg atc ggc agc ggt aaa tct acc gtt gcc gat ctt ttg 163 Leu Thr Gly Gly Ile Gly Ser Gly Lys Ser Thr Val Ala Asp Leu Leu 10 15 20 tca tct gaa gga ttt ctc atc gtc gac gcg gac caa gtt gcc cgc gat 211 Ser Ser Glu Gly Phe Leu Ile Val Asp Ala Asp Gln Val Ala Arg Asp 25 30 35 atc gtc gaa ccc gga caa ccg gca tta gca gag cta gct gaa gct ttt 259 Ile Val Glu Pro Gly Gln Pro Ala Leu Ala Glu Leu Ala Glu Ala Phe 40 45 50 ggc caa gac atc tta aaa ccc gac ggc act cta gac cgc gcg gga tta 307 Gly Gln Asp Ile Leu Lys Pro Asp Gly Thr Leu Asp Arg Ala Gly Leu 55 60 65 gca gcc aaa gca ttt gtc agc gaa gaa caa aca gcg ctg ctc aat gcc 355 Ala Ala Lys Ala Phe Val Ser Glu Glu Gln Thr Ala Leu Leu Asn Ala 70 75 80 85 att acc cac cct cgt atc gcc gaa gag tca gct cgt cga ttc aac gaa 403 Ile Thr His Pro Arg Ile Ala Glu Glu Ser Ala Arg Arg Phe Asn Glu 90 95 100 gcc gaa gat caa ggc gcc aaa gtt gcg gtt tat gac atg cct ttg ctt 451 Ala Glu Asp Gln Gly Ala Lys Val Ala Val Tyr Asp Met Pro Leu Leu 105 110 115 gta gaa aaa ggc ctt gac cgc aag atg gac ctt gtc gtc gta gtt gat 499 Val Glu Lys Gly Leu Asp Arg Lys Met Asp Leu Val Val Val Val Asp 120 125 130 gtt gac gta gag gaa cgc gtc cgc aga ctt gtg gaa aaa cgt ggc ctc 547 Val Asp Val Glu Glu Arg Val Arg Arg Leu Val Glu Lys Arg Gly Leu 135 140 145 aca gag gac gac gtg cgg cgt cga atc gct tct caa gtg ccc gac gac 595 Thr Glu Asp Asp Val Arg Arg Arg Ile Ala Ser Gln Val Pro Asp Asp 150 155 160 165 gtc aga ctt aaa gcc gct gac atc gtt gtg gac aat aac ggc acg cta 643 Val Arg Leu Lys Ala Ala Asp Ile Val Val Asp Asn Asn Gly Thr Leu 170 175 180 gag gac ctt cat gct gaa gca agc aag ctg att gct gag att ctt agt 691 Glu Asp Leu His Ala Glu Ala Ser Lys Leu Ile Ala Glu Ile Leu Ser 185 190 195 cgc gtg aat tagcactaaa acatcgtcaa agt 723 Arg Val Asn 200 <210> 732 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 732 Met Leu Arg Ile Gly Leu Thr Gly Gly Ile Gly Ser Gly Lys Ser Thr 1 5 10 15 Val Ala Asp Leu Leu Ser Ser Glu Gly Phe Leu Ile Val Asp Ala Asp 20 25 30 Gln Val Ala Arg Asp Ile Val Glu Pro Gly Gln Pro Ala Leu Ala Glu 35 40 45 Leu Ala Glu Ala Phe Gly Gln Asp Ile Leu Lys Pro Asp Gly Thr Leu 50 55 60 Asp Arg Ala Gly Leu Ala Ala Lys Ala Phe Val Ser Glu Glu Gln Thr 65 70 75 80 Ala Leu Leu Asn Ala Ile Thr His Pro Arg Ile Ala Glu Glu Ser Ala 85 90 95 Arg Arg Phe Asn Glu Ala Glu Asp Gln Gly Ala Lys Val Ala Val Tyr 100 105 110 Asp Met Pro Leu Leu Val Glu Lys Gly Leu Asp Arg Lys Met Asp Leu 115 120 125 Val Val Val Val Asp Val Asp Val Glu Glu Arg Val Arg Arg Leu Val 130 135 140 Glu Lys Arg Gly Leu Thr Glu Asp Asp Val Arg Arg Arg Ile Ala Ser 145 150 155 160 Gln Val Pro Asp Asp Val Arg Leu Lys Ala Ala Asp Ile Val Val Asp 165 170 175 Asn Asn Gly Thr Leu Glu Asp Leu His Ala Glu Ala Ser Lys Leu Ile 180 185 190 Ala Glu Ile Leu Ser Arg Val Asn 195 200 <210> 733 <211> 1194 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1171) <223> RXN02802 <400> 733 ccttcgccgc ctgctccgac ctcgccgacg ccgtcaaagc ccaggtcccg atctggaaag 60 agcaaacgcg cctcgacggc tccaccgatt gggtcggcct gtg aaa aac ctc gac 115 Val Lys Asn Leu Asp 1 5 atc gcc cgc tac cgc cgc caa att atg ctc ggc gaa atc ggc cag caa 163 Ile Ala Arg Tyr Arg Arg Gln Ile Met Leu Gly Glu Ile Gly Gln Gln 10 15 20 aaa caa caa tcg ctt ttc gac gct aag gtc tcc gtc atc ggc gca ggc 211 Lys Gln Gln Ser Leu Phe Asp Ala Lys Val Ser Val Ile Gly Ala Gly 25 30 35 ggc ctc ggg tca ccc gcc ctg ctc tac ctt gct ggc gct ggc gtc ggc 259 Gly Leu Gly Ser Pro Ala Leu Leu Tyr Leu Ala Gly Ala Gly Val Gly 40 45 50 cac atc cac atc att gac gat gac ctc gtc gac ctc tcc aac ctc cac 307 His Ile His Ile Ile Asp Asp Asp Leu Val Asp Leu Ser Asn Leu His 55 60 65 cgc cag gtc att cac acc acc gct ggc gtt gga aca ccc aag gcc gag 355 Arg Gln Val Ile His Thr Thr Ala Gly Val Gly Thr Pro Lys Ala Glu 70 75 80 85 tcc gcg cgc gaa gca atg ctg gca ctg aac cct tcc gtt aaa gtg acg 403 Ser Ala Arg Glu Ala Met Leu Ala Leu Asn Pro Ser Val Lys Val Thr 90 95 100 gtt tct gtc agg cga ctg gac tgg tca aat gca ctt tct gag ctg gca 451 Val Ser Val Arg Arg Leu Asp Trp Ser Asn Ala Leu Ser Glu Leu Ala 105 110 115 gat tcc gat gtg att ttg gat ggc tcc gat aac ttc gac acc cga cac 499 Asp Ser Asp Val Ile Leu Asp Gly Ser Asp Asn Phe Asp Thr Arg His 120 125 130 ctc gca tcc tgg gcc gcc gca aaa ctt ggc atc ccc cac gtc tgg gca 547 Leu Ala Ser Trp Ala Ala Ala Lys Leu Gly Ile Pro His Val Trp Ala 135 140 145 tcc atc ctg ggt ttc gac gcc caa ctc tcc gtc ttc cac gcc ggc cac 595 Ser Ile Leu Gly Phe Asp Ala Gln Leu Ser Val Phe His Ala Gly His 150 155 160 165 ggc ccc atc tac gaa gac ctc ttc ccc acc ccg cca cca ccc gga tcc 643 Gly Pro Ile Tyr Glu Asp Leu Phe Pro Thr Pro Pro Pro Pro Gly Ser 170 175 180 gtc cca tca tgt tcc caa gca ggc gtt ttg ggt cca gtt gtc ggc gta 691 Val Pro Ser Cys Ser Gln Ala Gly Val Leu Gly Pro Val Val Gly Val 185 190 195 atg ggc tcc gcg atg gcc atg gaa gcc ctg aaa atc atc acc ggc gtg 739 Met Gly Ser Ala Met Ala Met Glu Ala Leu Lys Ile Ile Thr Gly Val 200 205 210 ggc aca ccc ttg atc gga aaa ctc ggc tac tac tcc tcc ctc gac ggc 787 Gly Thr Pro Leu Ile Gly Lys Leu Gly Tyr Tyr Ser Ser Leu Asp Gly 215 220 225 acc tgg gaa tac atc ccc gtc gtc ggt tcg ccg gag gtg ctg gaa cgg 835 Thr Trp Glu Tyr Ile Pro Val Val Gly Ser Pro Glu Val Leu Glu Arg 230 235 240 245 gtg ctt ggg tct gct ggt gtt tcg ggg att tct ggc ggt ttt ggt gag 883 Val Leu Gly Ser Ala Gly Val Ser Gly Ile Ser Gly Gly Phe Gly Glu 250 255 260 gtg ctc gat gtt cct cga gtt tcc gcg ctg gtt gac ggc gtt tcg ctc 931 Val Leu Asp Val Pro Arg Val Ser Ala Leu Val Asp Gly Val Ser Leu 265 270 275 atc gac gtc cgc gaa ccc tcc gaa ttc tcc gcc tac tcc atc ccc ggc 979 Ile Asp Val Arg Glu Pro Ser Glu Phe Ser Ala Tyr Ser Ile Pro Gly 280 285 290 gcg cac aac acc cca ctg tcc gcc atc cgc gaa ggc gcc atc cca ccc 1027 Ala His Asn Thr Pro Leu Ser Ala Ile Arg Glu Gly Ala Ile Pro Pro 295 300 305 tcc gtt tcc gca ggt aaa gag gtt atc gtc tac tgc gca gct ggt gtc 1075 Ser Val Ser Ala Gly Lys Glu Val Ile Val Tyr Cys Ala Ala Gly Val 310 315 320 325 cgc tcc gca caa gcc atc gca att tta gaa tcc gca ggc tac acc gga 1123 Arg Ser Ala Gln Ala Ile Ala Ile Leu Glu Ser Ala Gly Tyr Thr Gly 330 335 340 atg agc agc ctc gac ggc gga atc gaa ggc tgg cta gat tcc cta ggg 1171 Met Ser Ser Leu Asp Gly Gly Ile Glu Gly Trp Leu Asp Ser Leu Gly 345 350 355 taaaaccaag gcgttgtgcc acc 1194 <210> 734 <211> 357 <212> PRT <213> Corynebacterium glutamicum <400> 734 Val Lys Asn Leu Asp Ile Ala Arg Tyr Arg Arg Gln Ile Met Leu Gly 1 5 10 15 Glu Ile Gly Gln Gln Lys Gln Gln Ser Leu Phe Asp Ala Lys Val Ser 20 25 30 Val Ile Gly Ala Gly Gly Leu Gly Ser Pro Ala Leu Leu Tyr Leu Ala 35 40 45 Gly Ala Gly Val Gly His Ile His Ile Ile Asp Asp Asp Leu Val Asp 50 55 60 Leu Ser Asn Leu His Arg Gln Val Ile His Thr Thr Ala Gly Val Gly 65 70 75 80 Thr Pro Lys Ala Glu Ser Ala Arg Glu Ala Met Leu Ala Leu Asn Pro 85 90 95 Ser Val Lys Val Thr Val Ser Val Arg Arg Leu Asp Trp Ser Asn Ala 100 105 110 Leu Ser Glu Leu Ala Asp Ser Asp Val Ile Leu Asp Gly Ser Asp Asn 115 120 125 Phe Asp Thr Arg His Leu Ala Ser Trp Ala Ala Ala Lys Leu Gly Ile 130 135 140 Pro His Val Trp Ala Ser Ile Leu Gly Phe Asp Ala Gln Leu Ser Val 145 150 155 160 Phe His Ala Gly His Gly Pro Ile Tyr Glu Asp Leu Phe Pro Thr Pro 165 170 175 Pro Pro Pro Gly Ser Val Pro Ser Cys Ser Gln Ala Gly Val Leu Gly 180 185 190 Pro Val Val Gly Val Met Gly Ser Ala Met Ala Met Glu Ala Leu Lys 195 200 205 Ile Ile Thr Gly Val Gly Thr Pro Leu Ile Gly Lys Leu Gly Tyr Tyr 210 215 220 Ser Ser Leu Asp Gly Thr Trp Glu Tyr Ile Pro Val Val Gly Ser Pro 225 230 235 240 Glu Val Leu Glu Arg Val Leu Gly Ser Ala Gly Val Ser Gly Ile Ser 245 250 255 Gly Gly Phe Gly Glu Val Leu Asp Val Pro Arg Val Ser Ala Leu Val 260 265 270 Asp Gly Val Ser Leu Ile Asp Val Arg Glu Pro Ser Glu Phe Ser Ala 275 280 285 Tyr Ser Ile Pro Gly Ala His Asn Thr Pro Leu Ser Ala Ile Arg Glu 290 295 300 Gly Ala Ile Pro Pro Ser Val Ser Ala Gly Lys Glu Val Ile Val Tyr 305 310 315 320 Cys Ala Ala Gly Val Arg Ser Ala Gln Ala Ile Ala Ile Leu Glu Ser 325 330 335 Ala Gly Tyr Thr Gly Met Ser Ser Leu Asp Gly Gly Ile Glu Gly Trp 340 345 350 Leu Asp Ser Leu Gly 355 <210> 735 <211> 497 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (7)..(474) <223> FRXA02802 <400> 735 tccgcg atg gcc atg gaa gcc ctg aaa atc atc acc ggc gtg ggc aca ccc 51 Met Ala Met Glu Ala Leu Lys Ile Ile Thr Gly Val Gly Thr Pro 1 5 10 15 ttg atc gga aaa ctc ggc tac tac tcc tcc ctc gac ggc acc tgg gaa 99 Leu Ile Gly Lys Leu Gly Tyr Tyr Ser Ser Leu Asp Gly Thr Trp Glu 20 25 30 tac atc ccc gtc gtc ggt tcg ccg gag gtg ctg gaa cgg gtg ctt ggg 147 Tyr Ile Pro Val Val Gly Ser Pro Glu Val Leu Glu Arg Val Leu Gly 35 40 45 tct gct ggt gtt tcg ggg att tct ggc ggt ttt ggt gag gtg ctc gat 195 Ser Ala Gly Val Ser Gly Ile Ser Gly Gly Phe Gly Glu Val Leu Asp 50 55 60 gtt cct cga gtt tcc gcg ctg gtt gac ggc gtt tcg ctc atc gac gtc 243 Val Pro Arg Val Ser Ala Leu Val Asp Gly Val Ser Leu Ile Asp Val 65 70 75 cgc gaa ccc tcc gaa ttc tcc gcc tac tcc atc ccc ggc gcg cac aac 291 Arg Glu Pro Ser Glu Phe Ser Ala Tyr Ser Ile Pro Gly Ala His Asn 80 85 90 95 acc cca ctg tcc gcc atc cgc gaa ggc gcc atc cca ccc tcc gtt tcc 339 Thr Pro Leu Ser Ala Ile Arg Glu Gly Ala Ile Pro Pro Ser Val Ser 100 105 110 gca ggt aaa gag gtt atc gtc tac tgc gca gct ggt gtc cgc tcc gca 387 Ala Gly Lys Glu Val Ile Val Tyr Cys Ala Ala Gly Val Arg Ser Ala 115 120 125 caa gcc atc gca att tta gaa tcc gca ggc tac acc gga atg agc agc 435 Gln Ala Ile Ala Ile Leu Glu Ser Ala Gly Tyr Thr Gly Met Ser Ser 130 135 140 ctc gac ggc gga atc gaa ggc tgg cta gat tcc cta ggg taaaaccaag 484 Leu Asp Gly Gly Ile Glu Gly Trp Leu Asp Ser Leu Gly 145 150 155 gcgttgtgcc acc 497 <210> 736 <211> 156 <212> PRT <213> Corynebacterium glutamicum <400> 736 Met Ala Met Glu Ala Leu Lys Ile Ile Thr Gly Val Gly Thr Pro Leu 1 5 10 15 Ile Gly Lys Leu Gly Tyr Tyr Ser Ser Leu Asp Gly Thr Trp Glu Tyr 20 25 30 Ile Pro Val Val Gly Ser Pro Glu Val Leu Glu Arg Val Leu Gly Ser 35 40 45 Ala Gly Val Ser Gly Ile Ser Gly Gly Phe Gly Glu Val Leu Asp Val 50 55 60 Pro Arg Val Ser Ala Leu Val Asp Gly Val Ser Leu Ile Asp Val Arg 65 70 75 80 Glu Pro Ser Glu Phe Ser Ala Tyr Ser Ile Pro Gly Ala His Asn Thr 85 90 95 Pro Leu Ser Ala Ile Arg Glu Gly Ala Ile Pro Pro Ser Val Ser Ala 100 105 110 Gly Lys Glu Val Ile Val Tyr Cys Ala Ala Gly Val Arg Ser Ala Gln 115 120 125 Ala Ile Ala Ile Leu Glu Ser Ala Gly Tyr Thr Gly Met Ser Ser Leu 130 135 140 Asp Gly Gly Ile Glu Gly Trp Leu Asp Ser Leu Gly 145 150 155 <210> 737 <211> 535 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(535) <223> FRXA00438 <400> 737 ccttcgccgc ctgctccgac ctcgccgacg ccgtcaaagc ccaggtcccg atctggaaag 60 agcaaacgcg cctcgacggc tccaccgatt gggtcggcct gtg aaa aac ctc gac 115 Val Lys Asn Leu Asp 1 5 atc gcc cgc tac cgc cgc caa att atg ctc ggc gaa atc ggc cag caa 163 Ile Ala Arg Tyr Arg Arg Gln Ile Met Leu Gly Glu Ile Gly Gln Gln 10 15 20 aaa caa caa tcg ctt ttc gac gct aag gtc tcc gtc atc ggc gca ggc 211 Lys Gln Gln Ser Leu Phe Asp Ala Lys Val Ser Val Ile Gly Ala Gly 25 30 35 ggc ctc ggg tca ccc gcc ctg ctc tac ctt gct ggc gct ggc gtc ggc 259 Gly Leu Gly Ser Pro Ala Leu Leu Tyr Leu Ala Gly Ala Gly Val Gly 40 45 50 cac atc cac atc att gac gat gac ctc gtc gac ctc tcc aac ctc cac 307 His Ile His Ile Ile Asp Asp Asp Leu Val Asp Leu Ser Asn Leu His 55 60 65 cgc cag gtc att cac acc acc gct ggc gtt gga aca ccc aag gcc gag 355 Arg Gln Val Ile His Thr Thr Ala Gly Val Gly Thr Pro Lys Ala Glu 70 75 80 85 tcc gcg cgc gaa gca atg ctg gca ctg aac cct tcc gtt aaa gtg acg 403 Ser Ala Arg Glu Ala Met Leu Ala Leu Asn Pro Ser Val Lys Val Thr 90 95 100 gtt tct gtc agg cga ctg gac tgg tca aat gca ctt tct gag ctg gca 451 Val Ser Val Arg Arg Leu Asp Trp Ser Asn Ala Leu Ser Glu Leu Ala 105 110 115 gat tcc gat gtg att ttg gat ggc tcc gat aac ttc gac acc cga cac 499 Asp Ser Asp Val Ile Leu Asp Gly Ser Asp Asn Phe Asp Thr Arg His 120 125 130 ctc gca tcc tgg gcc gcc gca aaa ctt ggc atc ccc 535 Leu Ala Ser Trp Ala Ala Ala Lys Leu Gly Ile Pro 135 140 145 <210> 738 <211> 145 <212> PRT <213> Corynebacterium glutamicum <400> 738 Val Lys Asn Leu Asp Ile Ala Arg Tyr Arg Arg Gln Ile Met Leu Gly 1 5 10 15 Glu Ile Gly Gln Gln Lys Gln Gln Ser Leu Phe Asp Ala Lys Val Ser 20 25 30 Val Ile Gly Ala Gly Gly Leu Gly Ser Pro Ala Leu Leu Tyr Leu Ala 35 40 45 Gly Ala Gly Val Gly His Ile His Ile Ile Asp Asp Asp Leu Val Asp 50 55 60 Leu Ser Asn Leu His Arg Gln Val Ile His Thr Thr Ala Gly Val Gly 65 70 75 80 Thr Pro Lys Ala Glu Ser Ala Arg Glu Ala Met Leu Ala Leu Asn Pro 85 90 95 Ser Val Lys Val Thr Val Ser Val Arg Arg Leu Asp Trp Ser Asn Ala 100 105 110 Leu Ser Glu Leu Ala Asp Ser Asp Val Ile Leu Asp Gly Ser Asp Asn 115 120 125 Phe Asp Thr Arg His Leu Ala Ser Trp Ala Ala Ala Lys Leu Gly Ile 130 135 140 Pro 145 <210> 739 <211> 579 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(556) <223> RXN00437 <400> 739 ttcatcatgg cgctgcccgg ctccacgggt gcggcgcgcg atgccaccgc tgtcctcgac 60 ccactcattg atcacatcac tggaactctg caaggccacc atg aac act gac ccc 115 Met Asn Thr Asp Pro 1 5 gct tac gtc gcc gaa caa acc ggc aaa ctc atc gac gct ttc ctc acc 163 Ala Tyr Val Ala Glu Gln Thr Gly Lys Leu Ile Asp Ala Phe Leu Thr 10 15 20 acc gac ccc ctc gaa ccg ctg ctc gac gcc gcc aaa aac ggc gtc tgc 211 Thr Asp Pro Leu Glu Pro Leu Leu Asp Ala Ala Lys Asn Gly Val Cys 25 30 35 aca gag gcg atg ggc gcg ctg gtc acc ttc gaa ggc atc gtc cgc gac 259 Thr Glu Ala Met Gly Ala Leu Val Thr Phe Glu Gly Ile Val Arg Asp 40 45 50 cac gac ggc ggc gcc cgc gtg acc tcc ctg acc tac acc gcg cat ccc 307 His Asp Gly Gly Ala Arg Val Thr Ser Leu Thr Tyr Thr Ala His Pro 55 60 65 acc gcg ccg cag gtc ctt tct gct gtc gcg gac tcc atc gtt gaa aaa 355 Thr Ala Pro Gln Val Leu Ser Ala Val Ala Asp Ser Ile Val Glu Lys 70 75 80 85 cac ccg cgc acc cgc ctc tgg acc gcg cac cgc acc ggc gcc ttg aaa 403 His Pro Arg Thr Arg Leu Trp Thr Ala His Arg Thr Gly Ala Leu Lys 90 95 100 atc ggt gac gcc gcc ttc ctc gtc gtc gcc gcc tcc gcc cac cgc gcc 451 Ile Gly Asp Ala Ala Phe Leu Val Val Ala Ala Ser Ala His Arg Ala 105 110 115 gac gcc ttc gcc gcc tgc tcc gac ctc gcc gac gcc gtc aaa gcc cag 499 Asp Ala Phe Ala Ala Cys Ser Asp Leu Ala Asp Ala Val Lys Ala Gln 120 125 130 gtc ccg atc tgg aaa gag caa acg cgc ctc gac ggc tcc acc gat tgg 547 Val Pro Ile Trp Lys Glu Gln Thr Arg Leu Asp Gly Ser Thr Asp Trp 135 140 145 gtc ggc ctg tgaaaaacct cgacatcgcc cgc 579 Val Gly Leu 150 <210> 740 <211> 152 <212> PRT <213> Corynebacterium glutamicum <400> 740 Met Asn Thr Asp Pro Ala Tyr Val Ala Glu Gln Thr Gly Lys Leu Ile 1 5 10 15 Asp Ala Phe Leu Thr Thr Asp Pro Leu Glu Pro Leu Leu Asp Ala Ala 20 25 30 Lys Asn Gly Val Cys Thr Glu Ala Met Gly Ala Leu Val Thr Phe Glu 35 40 45 Gly Ile Val Arg Asp His Asp Gly Gly Ala Arg Val Thr Ser Leu Thr 50 55 60 Tyr Thr Ala His Pro Thr Ala Pro Gln Val Leu Ser Ala Val Ala Asp 65 70 75 80 Ser Ile Val Glu Lys His Pro Arg Thr Arg Leu Trp Thr Ala His Arg 85 90 95 Thr Gly Ala Leu Lys Ile Gly Asp Ala Ala Phe Leu Val Val Ala Ala 100 105 110 Ser Ala His Arg Ala Asp Ala Phe Ala Ala Cys Ser Asp Leu Ala Asp 115 120 125 Ala Val Lys Ala Gln Val Pro Ile Trp Lys Glu Gln Thr Arg Leu Asp 130 135 140 Gly Ser Thr Asp Trp Val Gly Leu 145 150 <210> 741 <211> 383 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(360) <223> FRXA00437 <400> 741 aaa aac ggc gtc tgc aca gag gcg atg ggc gcg ctg gtc acc ttc gaa 48 Lys Asn Gly Val Cys Thr Glu Ala Met Gly Ala Leu Val Thr Phe Glu 1 5 10 15 ggc atc gtc cgc gac cac gac ggc ggc gcc cgc gtg acc tcc ctg acc 96 Gly Ile Val Arg Asp His Asp Gly Gly Ala Arg Val Thr Ser Leu Thr 20 25 30 tac acc gcg cat ccc acc gcg ccg cag gtc ctt tct gct gtc gcg gac 144 Tyr Thr Ala His Pro Thr Ala Pro Gln Val Leu Ser Ala Val Ala Asp 35 40 45 tcc atc gtt gaa aaa cac ccg cgc acc cgc ctc tgg acc gcg cac cgc 192 Ser Ile Val Glu Lys His Pro Arg Thr Arg Leu Trp Thr Ala His Arg 50 55 60 acc ggc gcc ttg aaa atc ggt gac gcc gcc ttc ctc gtc gtc gcc gcc 240 Thr Gly Ala Leu Lys Ile Gly Asp Ala Ala Phe Leu Val Val Ala Ala 65 70 75 80 tcc gcc cac cgc gcc gac gcc ttc gcc gcc tgc tcc gac ctc gcc gac 288 Ser Ala His Arg Ala Asp Ala Phe Ala Ala Cys Ser Asp Leu Ala Asp 85 90 95 gcc gtc aaa gcc cag gtc ccg atc tgg aaa gag caa acg cgc ctc gac 336 Ala Val Lys Ala Gln Val Pro Ile Trp Lys Glu Gln Thr Arg Leu Asp 100 105 110 ggc tcc acc gat tgg gtc ggc ctg tgaaaaacct cgacatcgcc cgc 383 Gly Ser Thr Asp Trp Val Gly Leu 115 120 <210> 742 <211> 120 <212> PRT <213> Corynebacterium glutamicum <400> 742 Lys Asn Gly Val Cys Thr Glu Ala Met Gly Ala Leu Val Thr Phe Glu 1 5 10 15 Gly Ile Val Arg Asp His Asp Gly Gly Ala Arg Val Thr Ser Leu Thr 20 25 30 Tyr Thr Ala His Pro Thr Ala Pro Gln Val Leu Ser Ala Val Ala Asp 35 40 45 Ser Ile Val Glu Lys His Pro Arg Thr Arg Leu Trp Thr Ala His Arg 50 55 60 Thr Gly Ala Leu Lys Ile Gly Asp Ala Ala Phe Leu Val Val Ala Ala 65 70 75 80 Ser Ala His Arg Ala Asp Ala Phe Ala Ala Cys Ser Asp Leu Ala Asp 85 90 95 Ala Val Lys Ala Gln Val Pro Ile Trp Lys Glu Gln Thr Arg Leu Asp 100 105 110 Gly Ser Thr Asp Trp Val Gly Leu 115 120 <210> 743 <211> 591 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(568) <223> RXN00439 <400> 743 ctgccaccgc agactgtctg atcaggatcc cggcgcggac tacggtggag gaaaacgaca 60 tcgttaagat ttacccattc aactaacagg agttaattta atg agc gag ctc acc 115 Met Ser Glu Leu Thr 1 5 cac gtt cga gca gac ggt tcc gca cat atg gtg gat gtg acg ggc aaa 163 His Val Arg Ala Asp Gly Ser Ala His Met Val Asp Val Thr Gly Lys 10 15 20 aat gaa aca tcg aga act gct gtt gcc gaa ggg ttt gtg aag atg agg 211 Asn Glu Thr Ser Arg Thr Ala Val Ala Glu Gly Phe Val Lys Met Arg 25 30 35 ggg gac gtc gta aag cag ctt ttt agt gct ggt ctg cct aaa ggc gac 259 Gly Asp Val Val Lys Gln Leu Phe Ser Ala Gly Leu Pro Lys Gly Asp 40 45 50 gcg cta cct gtg gcg cgg att gcg ggt atc atg ggt gcg aag aag acg 307 Ala Leu Pro Val Ala Arg Ile Ala Gly Ile Met Gly Ala Lys Lys Thr 55 60 65 ccg gac att atc cct tta tgc cac ccg ttg ccg ctg ggc aaa att act 355 Pro Asp Ile Ile Pro Leu Cys His Pro Leu Pro Leu Gly Lys Ile Thr 70 75 80 85 gtg gat ttt ttt gag ctt act gat ggt gtt cgg att gag gct tcg gtg 403 Val Asp Phe Phe Glu Leu Thr Asp Gly Val Arg Ile Glu Ala Ser Val 90 95 100 aaa acg cgt ggg gtt act ggt gtg gaa atg gag gcg ttg acg gcc gtg 451 Lys Thr Arg Gly Val Thr Gly Val Glu Met Glu Ala Leu Thr Ala Val 105 110 115 agc act gcg gcg ctg acg gta tac gac atg atc aag gct gtg gat aag 499 Ser Thr Ala Ala Leu Thr Val Tyr Asp Met Ile Lys Ala Val Asp Lys 120 125 130 atg gcc gtg att gat ggc att cgt gtg ctg tcg aaa act ggc ggt aaa 547 Met Ala Val Ile Asp Gly Ile Arg Val Leu Ser Lys Thr Gly Gly Lys 135 140 145 tct ggg gat tgg tct gtt cag tgacagctct ggttatcgtt gcg 591 Ser Gly Asp Trp Ser Val Gln 150 155 <210> 744 <211> 156 <212> PRT <213> Corynebacterium glutamicum <400> 744 Met Ser Glu Leu Thr His Val Arg Ala Asp Gly Ser Ala His Met Val 1 5 10 15 Asp Val Thr Gly Lys Asn Glu Thr Ser Arg Thr Ala Val Ala Glu Gly 20 25 30 Phe Val Lys Met Arg Gly Asp Val Val Lys Gln Leu Phe Ser Ala Gly 35 40 45 Leu Pro Lys Gly Asp Ala Leu Pro Val Ala Arg Ile Ala Gly Ile Met 50 55 60 Gly Ala Lys Lys Thr Pro Asp Ile Ile Pro Leu Cys His Pro Leu Pro 65 70 75 80 Leu Gly Lys Ile Thr Val Asp Phe Phe Glu Leu Thr Asp Gly Val Arg 85 90 95 Ile Glu Ala Ser Val Lys Thr Arg Gly Val Thr Gly Val Glu Met Glu 100 105 110 Ala Leu Thr Ala Val Ser Thr Ala Ala Leu Thr Val Tyr Asp Met Ile 115 120 125 Lys Ala Val Asp Lys Met Ala Val Ile Asp Gly Ile Arg Val Leu Ser 130 135 140 Lys Thr Gly Gly Lys Ser Gly Asp Trp Ser Val Gln 145 150 155 <210> 745 <211> 218 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(195) <223> FRXA00439 <400> 745 act gat ggt gtt cgg att gag gct tcg gtg aaa acg cgt ggg gtt act 48 Thr Asp Gly Val Arg Ile Glu Ala Ser Val Lys Thr Arg Gly Val Thr 1 5 10 15 ggt gtg gaa atg gag gcg ttg acg gcc gtg agc act gcg gcg ctg acg 96 Gly Val Glu Met Glu Ala Leu Thr Ala Val Ser Thr Ala Ala Leu Thr 20 25 30 gta tac gac atg atc aag gct gtg gat aag atg gcc gtg att gat ggc 144 Val Tyr Asp Met Ile Lys Ala Val Asp Lys Met Ala Val Ile Asp Gly 35 40 45 att cgt gtg ctg tcg aaa act ggc ggt aaa tct ggg gat tgg tct gtt 192 Ile Arg Val Leu Ser Lys Thr Gly Gly Lys Ser Gly Asp Trp Ser Val 50 55 60 cag tgacagctct ggttatcgtt gcg 218 Gln 65 <210> 746 <211> 65 <212> PRT <213> Corynebacterium glutamicum <400> 746 Thr Asp Gly Val Arg Ile Glu Ala Ser Val Lys Thr Arg Gly Val Thr 1 5 10 15 Gly Val Glu Met Glu Ala Leu Thr Ala Val Ser Thr Ala Ala Leu Thr 20 25 30 Val Tyr Asp Met Ile Lys Ala Val Asp Lys Met Ala Val Ile Asp Gly 35 40 45 Ile Arg Val Leu Ser Lys Thr Gly Gly Lys Ser Gly Asp Trp Ser Val 50 55 60 Gln 65 <210> 747 <211> 358 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(358) <223> FRXA00442 <400> 747 ctgccaccgc agactgtctg atcaggatcc cggcgcggac tacggtggag gaaaacgaca 60 tcgttaagat ttacccattc aactaacagg agttaattta atg agc gag ctc acc 115 Met Ser Glu Leu Thr 1 5 cac gtt cga gca gac ggt tcc gca cat atg gtg gat gtg acg ggc aaa 163 His Val Arg Ala Asp Gly Ser Ala His Met Val Asp Val Thr Gly Lys 10 15 20 aat gaa aca tcg aga act gct gtt gcc gaa ggg ttt gtg aag atg agg 211 Asn Glu Thr Ser Arg Thr Ala Val Ala Glu Gly Phe Val Lys Met Arg 25 30 35 ggg gac gtc gta aag cag ctt ttt agt gct ggt ctg cct aaa ggg gac 259 Gly Asp Val Val Lys Gln Leu Phe Ser Ala Gly Leu Pro Lys Gly Asp 40 45 50 gcg cta cct gtg gcg cgg att gcg ggt atc atg ggt gcg aag aag acg 307 Ala Leu Pro Val Ala Arg Ile Ala Gly Ile Met Gly Ala Lys Lys Thr 55 60 65 ccg gac att atc cct tta tgc cac ccg ttg ccg ctg ggc aaa att act 355 Pro Asp Ile Ile Pro Leu Cys His Pro Leu Pro Leu Gly Lys Ile Thr 70 75 80 85 gtg 358 Val <210> 748 <211> 86 <212> PRT <213> Corynebacterium glutamicum <400> 748 Met Ser Glu Leu Thr His Val Arg Ala Asp Gly Ser Ala His Met Val 1 5 10 15 Asp Val Thr Gly Lys Asn Glu Thr Ser Arg Thr Ala Val Ala Glu Gly 20 25 30 Phe Val Lys Met Arg Gly Asp Val Val Lys Gln Leu Phe Ser Ala Gly 35 40 45 Leu Pro Lys Gly Asp Ala Leu Pro Val Ala Arg Ile Ala Gly Ile Met 50 55 60 Gly Ala Lys Lys Thr Pro Asp Ile Ile Pro Leu Cys His Pro Leu Pro 65 70 75 80 Leu Gly Lys Ile Thr Val 85 <210> 749 <211> 582 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(559) <223> RXA00440 <400> 749 cggtatacga catgatcaag gctgtggata agatggccgt gattgatggc attcgtgtgc 60 tgtcgaaaac tggcggtaaa tctggggatt ggtctgttca gtg aca gct ctg gtt 115 Val Thr Ala Leu Val 1 5 atc gtt gcg tcc act cgc gcc gct gcc ggg gtg tat gag gat cgc tct 163 Ile Val Ala Ser Thr Arg Ala Ala Ala Gly Val Tyr Glu Asp Arg Ser 10 15 20 ggc cca att ttg gtg tcg tgg ctg cgt gca aaa ggt ttt gac aca ccc 211 Gly Pro Ile Leu Val Ser Trp Leu Arg Ala Lys Gly Phe Asp Thr Pro 25 30 35 gcc ccc gtg atc gtg gcg gac gcc aac ctg ccc gca ttc ctg gac gag 259 Ala Pro Val Ile Val Ala Asp Ala Asn Leu Pro Ala Phe Leu Asp Glu 40 45 50 ctg gaa ttt ccg cag gta gta ctt att tca ggc ggc acc gga ctc acg 307 Leu Glu Phe Pro Gln Val Val Leu Ile Ser Gly Gly Thr Gly Leu Thr 55 60 65 cct gat gac atc acc gtg gac act tta atc ccg cgc ctc gac aaa gaa 355 Pro Asp Asp Ile Thr Val Asp Thr Leu Ile Pro Arg Leu Asp Lys Glu 70 75 80 85 atc ccc ggc atc gcc cac gct ttt tgg aat tac agc atg gac gcc gtc 403 Ile Pro Gly Ile Ala His Ala Phe Trp Asn Tyr Ser Met Asp Ala Val 90 95 100 ccg acc gca gta ttg tcg cgc acc gtc gcg ggc acc atc ggc ggc agt 451 Pro Thr Ala Val Leu Ser Arg Thr Val Ala Gly Thr Ile Gly Gly Ser 105 110 115 ttc atc atg gcg ctg ccc ggc tcc acg ggt gcg gcg cgc gat gcc acc 499 Phe Ile Met Ala Leu Pro Gly Ser Thr Gly Ala Ala Arg Asp Ala Thr 120 125 130 gct gtc ctc gac cca ctc att gat cac atc act gga act ctg caa ggc 547 Ala Val Leu Asp Pro Leu Ile Asp His Ile Thr Gly Thr Leu Gln Gly 135 140 145 cac cat gaa cac tgaccccgct tacgtcgccg aac 582 His His Glu His 150 <210> 750 <211> 153 <212> PRT <213> Corynebacterium glutamicum <400> 750 Val Thr Ala Leu Val Ile Val Ala Ser Thr Arg Ala Ala Ala Gly Val 1 5 10 15 Tyr Glu Asp Arg Ser Gly Pro Ile Leu Val Ser Trp Leu Arg Ala Lys 20 25 30 Gly Phe Asp Thr Pro Ala Pro Val Ile Val Ala Asp Ala Asn Leu Pro 35 40 45 Ala Phe Leu Asp Glu Leu Glu Phe Pro Gln Val Val Leu Ile Ser Gly 50 55 60 Gly Thr Gly Leu Thr Pro Asp Asp Ile Thr Val Asp Thr Leu Ile Pro 65 70 75 80 Arg Leu Asp Lys Glu Ile Pro Gly Ile Ala His Ala Phe Trp Asn Tyr 85 90 95 Ser Met Asp Ala Val Pro Thr Ala Val Leu Ser Arg Thr Val Ala Gly 100 105 110 Thr Ile Gly Gly Ser Phe Ile Met Ala Leu Pro Gly Ser Thr Gly Ala 115 120 125 Ala Arg Asp Ala Thr Ala Val Leu Asp Pro Leu Ile Asp His Ile Thr 130 135 140 Gly Thr Leu Gln Gly His His Glu His 145 150 <210> 751 <211> 1287 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1264) <223> RXN00441 <400> 751 agccttggga gcggtgatta tgcttttggc tgtctatgtc ctcatcattg gagccatcgg 60 agcgttacga ttgttttcca aggtgagaaa ggtttaattg atg tct cgt tcg ccg 115 Met Ser Arg Ser Pro 1 5 gag caa cat ttg gca gaa att tca gcg ctg ctt ccc cca caa aag tcc 163 Glu Gln His Leu Ala Glu Ile Ser Ala Leu Leu Pro Pro Gln Lys Ser 10 15 20 acg ttc gtg aat ctg cgc gaa gcg ttg gga cgc cgc acg ttt tca gcg 211 Thr Phe Val Asn Leu Arg Glu Ala Leu Gly Arg Arg Thr Phe Ser Ala 25 30 35 gtc act gcg cag tgg gat tcg cca cgt ttt gat aat tcc caa atg gat 259 Val Thr Ala Gln Trp Asp Ser Pro Arg Phe Asp Asn Ser Gln Met Asp 40 45 50 ggc ttc gcg ctt ggc ccc tca cat ctt aac ggt ggc acc ttc gca gtc 307 Gly Phe Ala Leu Gly Pro Ser His Leu Asn Gly Gly Thr Phe Ala Val 55 60 65 ggt cca acc att ccc gct ggt cat gat cct gat cag tgg tac cca cga 355 Gly Pro Thr Ile Pro Ala Gly His Asp Pro Asp Gln Trp Tyr Pro Arg 70 75 80 85 ggc atc gaa aaa gac atc gcg ccg att atg acg ggt gcg cgc ctt cct 403 Gly Ile Glu Lys Asp Ile Ala Pro Ile Met Thr Gly Ala Arg Leu Pro 90 95 100 aaa aac acc gcc gcg atc att cct gtg gag aaa acc aca ccg gga aat 451 Lys Asn Thr Ala Ala Ile Ile Pro Val Glu Lys Thr Thr Pro Gly Asn 105 110 115 ttc gac gcc cca cag gta gaa atc ccc gcc acc ccg caa ggt cag ttc 499 Phe Asp Ala Pro Gln Val Glu Ile Pro Ala Thr Pro Gln Gly Gln Phe 120 125 130 ata cgg ttg cag ggt tcg gat att act gcc ggc gac gag atc att cca 547 Ile Arg Leu Gln Gly Ser Asp Ile Thr Ala Gly Asp Glu Ile Ile Pro 135 140 145 gca ggt acg gag ctt aac tcg gtg cac atc ggg gtg ttg gct agt cag 595 Ala Gly Thr Glu Leu Asn Ser Val His Ile Gly Val Leu Ala Ser Gln 150 155 160 165 tcg atc aag agc att gaa gtc gca gca aag cca cgt gtc ctc atc atc 643 Ser Ile Lys Ser Ile Glu Val Ala Ala Lys Pro Arg Val Leu Ile Ile 170 175 180 acc ggc ggg tct gaa att tca gaa cag cac gga ccc gcc acg atc cct 691 Thr Gly Gly Ser Glu Ile Ser Glu Gln His Gly Pro Ala Thr Ile Pro 185 190 195 gat gcc aac ggc cct ctg ctt cgt tcc ctg tgc gcc cgc aac aat atc 739 Asp Ala Asn Gly Pro Leu Leu Arg Ser Leu Cys Ala Arg Asn Asn Ile 200 205 210 gag gtc atc gcg gga ctg cac acc aac gac gat cct gaa cga ctc cgc 787 Glu Val Ile Ala Gly Leu His Thr Asn Asp Asp Pro Glu Arg Leu Arg 215 220 225 ttt gaa ctg gaa aac gcc att gac cag tat caa ccg gat gtc atc atc 835 Phe Glu Leu Glu Asn Ala Ile Asp Gln Tyr Gln Pro Asp Val Ile Ile 230 235 240 245 acc tct ggc ggt atc agc cac ggt aaa ttt gag gtg ttt agg cag atc 883 Thr Ser Gly Gly Ile Ser His Gly Lys Phe Glu Val Phe Arg Gln Ile 250 255 260 ctc gaa ggc acc ccg aac tcc tgg ttt gga cat gtc gat cag cag cct 931 Leu Glu Gly Thr Pro Asn Ser Trp Phe Gly His Val Asp Gln Gln Pro 265 270 275 ggc ggt cct caa ggc atc tcc act ttt gct gaa act cct gtc att tca 979 Gly Gly Pro Gln Gly Ile Ser Thr Phe Ala Glu Thr Pro Val Ile Ser 280 285 290 ctt ccc gga aat ccg att tcc acc ttg gtg agt ttc aca ctt ttg gtc 1027 Leu Pro Gly Asn Pro Ile Ser Thr Leu Val Ser Phe Thr Leu Leu Val 295 300 305 gcg cca gcg ctc aac cgc cag ccg ctc cgc cac ctc gat gcc cgc atc 1075 Ala Pro Ala Leu Asn Arg Gln Pro Leu Arg His Leu Asp Ala Arg Ile 310 315 320 325 acc gct ccg gtc cag ggc ttg caa gac aat cgc gag caa ttc ctt cgc 1123 Thr Ala Pro Val Gln Gly Leu Gln Asp Asn Arg Glu Gln Phe Leu Arg 330 335 340 ggc acc atc agt tac cgc aac ggg cca cgt cct cgc cac gcc tct cct 1171 Gly Thr Ile Ser Tyr Arg Asn Gly Pro Arg Pro Arg His Ala Ser Pro 345 350 355 ggg cac cag ttc cca cct gct ggt tca agc tgc cac cgc aga ctg tct 1219 Gly His Gln Phe Pro Pro Ala Gly Ser Ser Cys His Arg Arg Leu Ser 360 365 370 gat cag gat ccc ggc gcg gac tac ggt gga gga aaa cga cat cgt 1264 Asp Gln Asp Pro Gly Ala Asp Tyr Gly Gly Gly Lys Arg His Arg 375 380 385 taagatttac ccattcaact aac 1287 <210> 752 <211> 388 <212> PRT <213> Corynebacterium glutamicum <400> 752 Met Ser Arg Ser Pro Glu Gln His Leu Ala Glu Ile Ser Ala Leu Leu 1 5 10 15 Pro Pro Gln Lys Ser Thr Phe Val Asn Leu Arg Glu Ala Leu Gly Arg 20 25 30 Arg Thr Phe Ser Ala Val Thr Ala Gln Trp Asp Ser Pro Arg Phe Asp 35 40 45 Asn Ser Gln Met Asp Gly Phe Ala Leu Gly Pro Ser His Leu Asn Gly 50 55 60 Gly Thr Phe Ala Val Gly Pro Thr Ile Pro Ala Gly His Asp Pro Asp 65 70 75 80 Gln Trp Tyr Pro Arg Gly Ile Glu Lys Asp Ile Ala Pro Ile Met Thr 85 90 95 Gly Ala Arg Leu Pro Lys Asn Thr Ala Ala Ile Ile Pro Val Glu Lys 100 105 110 Thr Thr Pro Gly Asn Phe Asp Ala Pro Gln Val Glu Ile Pro Ala Thr 115 120 125 Pro Gln Gly Gln Phe Ile Arg Leu Gln Gly Ser Asp Ile Thr Ala Gly 130 135 140 Asp Glu Ile Ile Pro Ala Gly Thr Glu Leu Asn Ser Val His Ile Gly 145 150 155 160 Val Leu Ala Ser Gln Ser Ile Lys Ser Ile Glu Val Ala Ala Lys Pro 165 170 175 Arg Val Leu Ile Ile Thr Gly Gly Ser Glu Ile Ser Glu Gln His Gly 180 185 190 Pro Ala Thr Ile Pro Asp Ala Asn Gly Pro Leu Leu Arg Ser Leu Cys 195 200 205 Ala Arg Asn Asn Ile Glu Val Ile Ala Gly Leu His Thr Asn Asp Asp 210 215 220 Pro Glu Arg Leu Arg Phe Glu Leu Glu Asn Ala Ile Asp Gln Tyr Gln 225 230 235 240 Pro Asp Val Ile Ile Thr Ser Gly Gly Ile Ser His Gly Lys Phe Glu 245 250 255 Val Phe Arg Gln Ile Leu Glu Gly Thr Pro Asn Ser Trp Phe Gly His 260 265 270 Val Asp Gln Gln Pro Gly Gly Pro Gln Gly Ile Ser Thr Phe Ala Glu 275 280 285 Thr Pro Val Ile Ser Leu Pro Gly Asn Pro Ile Ser Thr Leu Val Ser 290 295 300 Phe Thr Leu Leu Val Ala Pro Ala Leu Asn Arg Gln Pro Leu Arg His 305 310 315 320 Leu Asp Ala Arg Ile Thr Ala Pro Val Gln Gly Leu Gln Asp Asn Arg 325 330 335 Glu Gln Phe Leu Arg Gly Thr Ile Ser Tyr Arg Asn Gly Pro Arg Pro 340 345 350 Arg His Ala Ser Pro Gly His Gln Phe Pro Pro Ala Gly Ser Ser Cys 355 360 365 His Arg Arg Leu Ser Asp Gln Asp Pro Gly Ala Asp Tyr Gly Gly Gly 370 375 380 Lys Arg His Arg 385 <210> 753 <211> 815 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(792) <223> FRXA00441 <400> 753 atc ccc gcc acc ccg caa ggt cag ttc ata cgg ttg cag ggt tcg gat 48 Ile Pro Ala Thr Pro Gln Gly Gln Phe Ile Arg Leu Gln Gly Ser Asp 1 5 10 15 att act gcc ggc gac gag atc att cca gca ggt acg gag ctt aac tcg 96 Ile Thr Ala Gly Asp Glu Ile Ile Pro Ala Gly Thr Glu Leu Asn Ser 20 25 30 gtg cac atc ggg gtg ttg gct agt cag tcg atc aag agc att gaa gtc 144 Val His Ile Gly Val Leu Ala Ser Gln Ser Ile Lys Ser Ile Glu Val 35 40 45 gca gca aag cca cgt gtc ctc atc atc acc ggc ggg tct gaa att tca 192 Ala Ala Lys Pro Arg Val Leu Ile Ile Thr Gly Gly Ser Glu Ile Ser 50 55 60 gaa cag cac gga ccc gcc acg atc cct gat gcc aac ggc cct ctg ctt 240 Glu Gln His Gly Pro Ala Thr Ile Pro Asp Ala Asn Gly Pro Leu Leu 65 70 75 80 cgt tcc ctg tgc gcc cgc aac aat atc gag gtc atc gcg gga ctg cac 288 Arg Ser Leu Cys Ala Arg Asn Asn Ile Glu Val Ile Ala Gly Leu His 85 90 95 acc aac gac gat cct gaa cga ctc cgc ttt gaa ctg gaa aac gcc att 336 Thr Asn Asp Asp Pro Glu Arg Leu Arg Phe Glu Leu Glu Asn Ala Ile 100 105 110 gac cag tat caa ccg gat gtc atc atc acc tct ggc ggt atc agc cac 384 Asp Gln Tyr Gln Pro Asp Val Ile Ile Thr Ser Gly Gly Ile Ser His 115 120 125 ggt aaa ttt gag gtg ttt agg cag atc ctc gaa ggc acc ccg aac tcc 432 Gly Lys Phe Glu Val Phe Arg Gln Ile Leu Glu Gly Thr Pro Asn Ser 130 135 140 tgg ttt gga cat gtc gat cag cag cct ggc ggt cct caa ggc atc tcc 480 Trp Phe Gly His Val Asp Gln Gln Pro Gly Gly Pro Gln Gly Ile Ser 145 150 155 160 act ttt gct gaa act cct gtc att tca ctt ccc gga aat ccg att tcc 528 Thr Phe Ala Glu Thr Pro Val Ile Ser Leu Pro Gly Asn Pro Ile Ser 165 170 175 acc ttg gtg agt ttc aca ctt ttg gtc gcg cca gcg ctc aac cgc cag 576 Thr Leu Val Ser Phe Thr Leu Leu Val Ala Pro Ala Leu Asn Arg Gln 180 185 190 ccg ctc cgc cac ctc gat gcc cgc atc acc gct ccg gtc cag ggc ttg 624 Pro Leu Arg His Leu Asp Ala Arg Ile Thr Ala Pro Val Gln Gly Leu 195 200 205 caa gac aat cgc gag caa ttc ctt cgc ggc acc atc agt tac cgc aac 672 Gln Asp Asn Arg Glu Gln Phe Leu Arg Gly Thr Ile Ser Tyr Arg Asn 210 215 220 ggg cca cgt cct cgc cac gcc tct cct ggg cac cag ttc cca cct gct 720 Gly Pro Arg Pro Arg His Ala Ser Pro Gly His Gln Phe Pro Pro Ala 225 230 235 240 ggt tca agc tgc cac cgc aga ctg tct gat cag gat ccc ggc gcg gac 768 Gly Ser Ser Cys His Arg Arg Leu Ser Asp Gln Asp Pro Gly Ala Asp 245 250 255 tac ggt gga gga aaa cga cat cgt taagatttac ccattcaact aac 815 Tyr Gly Gly Gly Lys Arg His Arg 260 <210> 754 <211> 264 <212> PRT <213> Corynebacterium glutamicum <400> 754 Ile Pro Ala Thr Pro Gln Gly Gln Phe Ile Arg Leu Gln Gly Ser Asp 1 5 10 15 Ile Thr Ala Gly Asp Glu Ile Ile Pro Ala Gly Thr Glu Leu Asn Ser 20 25 30 Val His Ile Gly Val Leu Ala Ser Gln Ser Ile Lys Ser Ile Glu Val 35 40 45 Ala Ala Lys Pro Arg Val Leu Ile Ile Thr Gly Gly Ser Glu Ile Ser 50 55 60 Glu Gln His Gly Pro Ala Thr Ile Pro Asp Ala Asn Gly Pro Leu Leu 65 70 75 80 Arg Ser Leu Cys Ala Arg Asn Asn Ile Glu Val Ile Ala Gly Leu His 85 90 95 Thr Asn Asp Asp Pro Glu Arg Leu Arg Phe Glu Leu Glu Asn Ala Ile 100 105 110 Asp Gln Tyr Gln Pro Asp Val Ile Ile Thr Ser Gly Gly Ile Ser His 115 120 125 Gly Lys Phe Glu Val Phe Arg Gln Ile Leu Glu Gly Thr Pro Asn Ser 130 135 140 Trp Phe Gly His Val Asp Gln Gln Pro Gly Gly Pro Gln Gly Ile Ser 145 150 155 160 Thr Phe Ala Glu Thr Pro Val Ile Ser Leu Pro Gly Asn Pro Ile Ser 165 170 175 Thr Leu Val Ser Phe Thr Leu Leu Val Ala Pro Ala Leu Asn Arg Gln 180 185 190 Pro Leu Arg His Leu Asp Ala Arg Ile Thr Ala Pro Val Gln Gly Leu 195 200 205 Gln Asp Asn Arg Glu Gln Phe Leu Arg Gly Thr Ile Ser Tyr Arg Asn 210 215 220 Gly Pro Arg Pro Arg His Ala Ser Pro Gly His Gln Phe Pro Pro Ala 225 230 235 240 Gly Ser Ser Cys His Arg Arg Leu Ser Asp Gln Asp Pro Gly Ala Asp 245 250 255 Tyr Gly Gly Gly Lys Arg His Arg 260 <210> 755 <211> 2358 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2335) <223> RXN02085 <400> 755 cacccggtga tttcgcgaac cttgaaacat cgtcagaaga ttgccgtgcg tcctagccgg 60 gatccgcacg ttcggctcaa gcagaaagtc tttaactcac atg act tcc aac ttt 115 Met Thr Ser Asn Phe 1 5 tct tcc act gtc gct ggt ctt cct cgc atc gga gcg aag cgt gaa ctg 163 Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly Ala Lys Arg Glu Leu 10 15 20 aag ttc gcg ctc gaa ggc tac tgg aat gga tca att gaa ggt cgc gaa 211 Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser Ile Glu Gly Arg Glu 25 30 35 ctt gcg cag acc gcc cgc caa ttg gtc aac act gca tcg gat tct ttg 259 Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr Ala Ser Asp Ser Leu 40 45 50 tct gga ttg gat tcc gtt ccg ttt gca gga cgt tcc tac tac gac gca 307 Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg Ser Tyr Tyr Asp Ala 55 60 65 atg ctc gat acc gcc gct att ttg ggt gtg ctg ccg gag cgt ttt gat 355 Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu Pro Glu Arg Phe Asp 70 75 80 85 gac atc gct gat cat gaa aac gat ggt ctc cca ctg tgg att gac cgc 403 Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro Leu Trp Ile Asp Arg 90 95 100 tac ttt ggc gct gct cgc ggt act gag acc ctg cct gca cag gca atg 451 Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu Pro Ala Gln Ala Met 105 110 115 acc aag tgg ttt gat acc aac tac cac tac ctc gtg ccg gag ttg tct 499 Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu Val Pro Glu Leu Ser 120 125 130 gcg gat aca cgt ttc gtt ttg gat gcg tcc gcg ctg att gag gat ctc 547 Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala Leu Ile Glu Asp Leu 135 140 145 cgt tgc cag cag gtt cgt ggc gtt aat gcc cgc cct gtt ctg gtt ggt 595 Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg Pro Val Leu Val Gly 150 155 160 165 cca ctg act ttc ctt tcc ctt gct cgc acc act gat ggt tcc aat cct 643 Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr Asp Gly Ser Asn Pro 170 175 180 ttg gat cac ctg cct gca ctg ttt gag gtc tac gag cgc ctc atc aag 691 Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr Glu Arg Leu Ile Lys 185 190 195 tct ttc gat act gag tgg gtt cag atc gat gag cct gcg ttg gtc acc 739 Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu Pro Ala Leu Val Thr 200 205 210 gat gtt gct cct gag gtt ttg gag cag gtc cgc gct ggt tac acc act 787 Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg Ala Gly Tyr Thr Thr 215 220 225 ttg gct aag cgc gat ggc gtg ttt gtc aat act tac ttc ggc tct ggc 835 Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr Tyr Phe Gly Ser Gly 230 235 240 245 gat cag gcg ctg aac act ctt gcg ggc atc ggc ctt ggc gcg att ggc 883 Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly Leu Gly Ala Ile Gly 250 255 260 gtt gac ttg gtc acc cat ggc gtc act gag ctt gct gcg tgg aag ggt 931 Val Asp Leu Val Thr His Gly Val Thr Glu Leu Ala Ala Trp Lys Gly 265 270 275 gag gag ctg ctg gtt gcg ggc atc gtt gat ggt cgt aac att tgg cgc 979 Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly Arg Asn Ile Trp Arg 280 285 290 acc gac ctg tgt gct gct ctt gct tcc ctg aag cgc ctg gca gct cgc 1027 Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys Arg Leu Ala Ala Arg 295 300 305 ggc cca atc gca gtg tct acc tct tgt tca ctg ctg cac gtt cct tac 1075 Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu Leu His Val Pro Tyr 310 315 320 325 acc ctc gag gct gag aac att gag cct gag gtc cgc gac tgg ctt gcc 1123 Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val Arg Asp Trp Leu Ala 330 335 340 ttc ggc tcg gag aag atc acc gag gtc aag ctg ctt gcc gac gcc cta 1171 Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu Leu Ala Asp Ala Leu 345 350 355 gcc ggc aac atc gac gcg gct gcg ttc gat gcg gcg tcc gca gca att 1219 Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala Ala Ser Ala Ala Ile 360 365 370 gct tct cga cgc acc tcc cca cgc acc gca cca atc acg cag gaa ctc 1267 Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro Ile Thr Gln Glu Leu 375 380 385 cct ggc cgt agc cgt gga tcc ttc gac act cgt gtt acg ctg cag gag 1315 Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg Val Thr Leu Gln Glu 390 395 400 405 aag tca ctg gag ctt cca gct ctg cca acc acc acc att ggt tct ttc 1363 Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr Thr Ile Gly Ser Phe 410 415 420 cca cag acc cca tcc att cgt tct gct cgc gct cgt ctg cgc aag gaa 1411 Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala Arg Leu Arg Lys Glu 425 430 435 tcc atc act ttg gag cag tac gaa gag gca atg cgc gaa gaa atc gat 1459 Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met Arg Glu Glu Ile Asp 440 445 450 ctg gtc atc gcc aag cag gaa gaa ctt ggt ctt gat gtg ttg gtt cac 1507 Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu Asp Val Leu Val His 455 460 465 ggt gag cca gag cgc aac gac atg gtt cag tac ttc tct gaa ctt ctc 1555 Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr Phe Ser Glu Leu Leu 470 475 480 485 gac ggt ttc ctc tca acc gcc aac ggc tgg gtc caa agc tac ggc tcc 1603 Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val Gln Ser Tyr Gly Ser 490 495 500 cgc tgt gtt cgt cct cca gtg ttg ttc gga aac gtt tcc cgc cca gcg 1651 Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn Val Ser Arg Pro Ala 505 510 515 cca atg act gtc aag tgg ttc cag tac gca cag agc ctg acc cag aag 1699 Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln Ser Leu Thr Gln Lys 520 525 530 cat gtc aag gga atg ctc acc ggt cca gtc acc atc ctt gca tgg tcc 1747 His Val Lys Gly Met Leu Thr Gly Pro Val Thr Ile Leu Ala Trp Ser 535 540 545 ttc gtt cgc gat gat cag ccg ctg gct acc act gct gac cag gtt gca 1795 Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr Ala Asp Gln Val Ala 550 555 560 565 ctg gca ctg cgc gat gaa att aac gat ctc atc gag gct ggc gcg aag 1843 Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile Glu Ala Gly Ala Lys 570 575 580 atc atc cag gtg gat gag cct gcg att cgt gaa ctg ttg ccg cta cga 1891 Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu Leu Leu Pro Leu Arg 585 590 595 gac gtc gat aag cct gcc tac ctg cag tgg tcc gtg gac tcc ttc cgc 1939 Asp Val Asp Lys Pro Ala Tyr Leu Gln Trp Ser Val Asp Ser Phe Arg 600 605 610 ctg gcg act gcc ggc gca ccc gac gac gtc caa atc cac acc cac atg 1987 Leu Ala Thr Ala Gly Ala Pro Asp Asp Val Gln Ile His Thr His Met 615 620 625 tgc tac tcc gag ttc aac gaa gtg atc tcc tcg gtc atc gcg ttg gat 2035 Cys Tyr Ser Glu Phe Asn Glu Val Ile Ser Ser Val Ile Ala Leu Asp 630 635 640 645 gcc gat gtc acc acc atc gaa gca gca cgt tcc gac atg cag gtc ctc 2083 Ala Asp Val Thr Thr Ile Glu Ala Ala Arg Ser Asp Met Gln Val Leu 650 655 660 gct gct ctg aaa tct tcc ggc ttc gag ctc ggc gtc gga cct ggt gtg 2131 Ala Ala Leu Lys Ser Ser Gly Phe Glu Leu Gly Val Gly Pro Gly Val 665 670 675 tgg gat atc cac tcc ccg cgc gtt cct tcc gcg cag aaa gtg gac ggt 2179 Trp Asp Ile His Ser Pro Arg Val Pro Ser Ala Gln Lys Val Asp Gly 680 685 690 ctc ctc gag gct gca ctg cag tcc gtg gat cct cgc cag ctg tgg gtc 2227 Leu Leu Glu Ala Ala Leu Gln Ser Val Asp Pro Arg Gln Leu Trp Val 695 700 705 aac cca gac tgt ggt ctg aag acc cgt gga tgg cca gaa gtg gaa gct 2275 Asn Pro Asp Cys Gly Leu Lys Thr Arg Gly Trp Pro Glu Val Glu Ala 710 715 720 725 tcc cta aag gtt ctc gtt gag tcc gct aag cag gct cgt gag aaa atc 2323 Ser Leu Lys Val Leu Val Glu Ser Ala Lys Gln Ala Arg Glu Lys Ile 730 735 740 gga gca act atc taaattgggt taccgctagg aac 2358 Gly Ala Thr Ile 745 <210> 756 <211> 745 <212> PRT <213> Corynebacterium glutamicum <400> 756 Met Thr Ser Asn Phe Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly 1 5 10 15 Ala Lys Arg Glu Leu Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser 20 25 30 Ile Glu Gly Arg Glu Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr 35 40 45 Ala Ser Asp Ser Leu Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg 50 55 60 Ser Tyr Tyr Asp Ala Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu 65 70 75 80 Pro Glu Arg Phe Asp Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro 85 90 95 Leu Trp Ile Asp Arg Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu 100 105 110 Pro Ala Gln Ala Met Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu 115 120 125 Val Pro Glu Leu Ser Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala 130 135 140 Leu Ile Glu Asp Leu Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg 145 150 155 160 Pro Val Leu Val Gly Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr 165 170 175 Asp Gly Ser Asn Pro Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr 180 185 190 Glu Arg Leu Ile Lys Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu 195 200 205 Pro Ala Leu Val Thr Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg 210 215 220 Ala Gly Tyr Thr Thr Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr 225 230 235 240 Tyr Phe Gly Ser Gly Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly 245 250 255 Leu Gly Ala Ile Gly Val Asp Leu Val Thr His Gly Val Thr Glu Leu 260 265 270 Ala Ala Trp Lys Gly Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly 275 280 285 Arg Asn Ile Trp Arg Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys 290 295 300 Arg Leu Ala Ala Arg Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu 305 310 315 320 Leu His Val Pro Tyr Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val 325 330 335 Arg Asp Trp Leu Ala Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu 340 345 350 Leu Ala Asp Ala Leu Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala 355 360 365 Ala Ser Ala Ala Ile Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro 370 375 380 Ile Thr Gln Glu Leu Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg 385 390 395 400 Val Thr Leu Gln Glu Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr 405 410 415 Thr Ile Gly Ser Phe Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala 420 425 430 Arg Leu Arg Lys Glu Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met 435 440 445 Arg Glu Glu Ile Asp Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu 450 455 460 Asp Val Leu Val His Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr 465 470 475 480 Phe Ser Glu Leu Leu Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val 485 490 495 Gln Ser Tyr Gly Ser Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn 500 505 510 Val Ser Arg Pro Ala Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln 515 520 525 Ser Leu Thr Gln Lys His Val Lys Gly Met Leu Thr Gly Pro Val Thr 530 535 540 Ile Leu Ala Trp Ser Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr 545 550 555 560 Ala Asp Gln Val Ala Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile 565 570 575 Glu Ala Gly Ala Lys Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu 580 585 590 Leu Leu Pro Leu Arg Asp Val Asp Lys Pro Ala Tyr Leu Gln Trp Ser 595 600 605 Val Asp Ser Phe Arg Leu Ala Thr Ala Gly Ala Pro Asp Asp Val Gln 610 615 620 Ile His Thr His Met Cys Tyr Ser Glu Phe Asn Glu Val Ile Ser Ser 625 630 635 640 Val Ile Ala Leu Asp Ala Asp Val Thr Thr Ile Glu Ala Ala Arg Ser 645 650 655 Asp Met Gln Val Leu Ala Ala Leu Lys Ser Ser Gly Phe Glu Leu Gly 660 665 670 Val Gly Pro Gly Val Trp Asp Ile His Ser Pro Arg Val Pro Ser Ala 675 680 685 Gln Lys Val Asp Gly Leu Leu Glu Ala Ala Leu Gln Ser Val Asp Pro 690 695 700 Arg Gln Leu Trp Val Asn Pro Asp Cys Gly Leu Lys Thr Arg Gly Trp 705 710 715 720 Pro Glu Val Glu Ala Ser Leu Lys Val Leu Val Glu Ser Ala Lys Gln 725 730 735 Ala Arg Glu Lys Ile Gly Ala Thr Ile 740 745 <210> 757 <211> 1923 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1900) <223> FRXA02085 <400> 757 cacccggtga tttcgcgaac cttgaaacat cgtcagaaga ttgccgtgcg tcctagccgg 60 gatccgcacg ttcggctcaa gcagaaagtc tttaactcac atg act tcc aac ttt 115 Met Thr Ser Asn Phe 1 5 tct tcc act gtc gct ggt ctt cct cgc atc gga gcg aag cgt gaa ctg 163 Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly Ala Lys Arg Glu Leu 10 15 20 aag ttc gcg ctc gaa ggc tac tgg aat gga tca att gaa ggt cgc gaa 211 Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser Ile Glu Gly Arg Glu 25 30 35 ctt gcg cag acc gcc cgc caa ttg gtc aac act gca tcg gat tct ttg 259 Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr Ala Ser Asp Ser Leu 40 45 50 tct gga ttg gat tcc gtt ccg ttt gca gga cgt tcc tac tac gac gca 307 Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg Ser Tyr Tyr Asp Ala 55 60 65 atg ctc gat acc gcc gct att ttg ggt gtg ctg ccg gag cgt ttt gat 355 Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu Pro Glu Arg Phe Asp 70 75 80 85 gac atc gct gat cat gaa aac gat ggt ctc cca ctg tgg att gac cgc 403 Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro Leu Trp Ile Asp Arg 90 95 100 tac ttt ggc gct gct cgc ggt act gag acc ctg cct gca cag gca atg 451 Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu Pro Ala Gln Ala Met 105 110 115 acc aag tgg ttt gat acc aac tac cac tac ctc gtg ccg gag ttg tct 499 Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu Val Pro Glu Leu Ser 120 125 130 gcg gat aca cgt ttc gtt ttg gat gcg tcc gcg ctg att gag gat ctc 547 Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala Leu Ile Glu Asp Leu 135 140 145 cgt tgc cag cag gtt cgt ggc gtt aat gcc cgc cct gtt ctg gtt ggt 595 Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg Pro Val Leu Val Gly 150 155 160 165 cca ctg act ttc ctt tcc ctt gct cgc acc act gat ggt tcc aat cct 643 Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr Asp Gly Ser Asn Pro 170 175 180 ttg gat cac ctg cct gca ctg ttt gag gtc tac gag cgc ctc atc aag 691 Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr Glu Arg Leu Ile Lys 185 190 195 tct ttc gat act gag tgg gtt cag atc gat gag cct gcg ttg gtc acc 739 Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu Pro Ala Leu Val Thr 200 205 210 gat gtt gct cct gag gtt ttg gag cag gtc cgc gct ggt tac acc act 787 Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg Ala Gly Tyr Thr Thr 215 220 225 ttg gct aag cgc gat ggc gtg ttt gtc aat act tac ttc ggc tct ggc 835 Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr Tyr Phe Gly Ser Gly 230 235 240 245 gat cag gcg ctg aac act ctt gcg ggc atc ggc ctt ggc gcg att ggc 883 Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly Leu Gly Ala Ile Gly 250 255 260 gtt gac ttg gtc acc cat ggc gtc act gag ctt gct gcg tgg aag ggt 931 Val Asp Leu Val Thr His Gly Val Thr Glu Leu Ala Ala Trp Lys Gly 265 270 275 gag gag ctg ctg gtt gcg ggc atc gtt gat ggt cgt aac att tgg cgc 979 Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly Arg Asn Ile Trp Arg 280 285 290 acc gac ctg tgt gct gct ctt gct tcc ctg aag cgc ctg gca gct cgc 1027 Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys Arg Leu Ala Ala Arg 295 300 305 ggc cca atc gca gtg tct acc tct tgt tca ctg ctg cac gtt cct tac 1075 Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu Leu His Val Pro Tyr 310 315 320 325 acc ctc gag gct gag aac att gag cct gag gtc cgc gac tgg ctt gcc 1123 Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val Arg Asp Trp Leu Ala 330 335 340 ttc ggc tcg gag aag atc acc gag gtc aag ctg ctt gcc gac gcc cta 1171 Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu Leu Ala Asp Ala Leu 345 350 355 gcc ggc aac atc gac gcg gct gcg ttc gat gcg gcg tcc gca gca att 1219 Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala Ala Ser Ala Ala Ile 360 365 370 gct tct cga cgc acc tcc cca cgc acc gca cca atc acg cag gaa ctc 1267 Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro Ile Thr Gln Glu Leu 375 380 385 cct ggc cgt agc cgt gga tcc ttc gac act cgt gtt acg ctg cag gag 1315 Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg Val Thr Leu Gln Glu 390 395 400 405 aag tca ctg gag ctt cca gct ctg cca acc acc acc att ggt tct ttc 1363 Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr Thr Ile Gly Ser Phe 410 415 420 cca cag acc cca tcc att cgt tct gct cgc gct cgt ctg cgc aag gaa 1411 Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala Arg Leu Arg Lys Glu 425 430 435 tcc atc act ttg gag cag tac gaa gag gca atg cgc gaa gaa atc gat 1459 Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met Arg Glu Glu Ile Asp 440 445 450 ctg gtc atc gcc aag cag gaa gaa ctt ggt ctt gat gtg ttg gtt cac 1507 Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu Asp Val Leu Val His 455 460 465 ggt gag cca gag cgc aac gac atg gtt cag tac ttc tct gaa ctt ctc 1555 Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr Phe Ser Glu Leu Leu 470 475 480 485 gac ggt ttc ctc tca acc gcc aac ggc tgg gtc caa agc tac ggc tcc 1603 Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val Gln Ser Tyr Gly Ser 490 495 500 cgc tgt gtt cgt cct cca gtg ttg ttc gga aac gtt tcc cgc cca gcg 1651 Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn Val Ser Arg Pro Ala 505 510 515 cca atg act gtc aag tgg ttc cag tac gca cag agc ctg acc cag aag 1699 Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln Ser Leu Thr Gln Lys 520 525 530 cat gtc aag gga atg ctc acc ggt cca gtc acc atc ctt gca tgg tcc 1747 His Val Lys Gly Met Leu Thr Gly Pro Val Thr Ile Leu Ala Trp Ser 535 540 545 ttc gtt cgc gat gat cag ccg ctg gct acc act gct gac cag gtt gca 1795 Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr Ala Asp Gln Val Ala 550 555 560 565 ctg gca ctg cgc gat gaa att aac gat ctc atc gag gct ggc gcg aag 1843 Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile Glu Ala Gly Ala Lys 570 575 580 atc atc cag gtg gat gag cct gcg att cgt gaa ctg ttg ccc gct acg 1891 Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu Leu Leu Pro Ala Thr 585 590 595 aga cgt cga taagcctgcc tacctgcagt ggt 1923 Arg Arg Arg 600 <210> 758 <211> 600 <212> PRT <213> Corynebacterium glutamicum <400> 758 Met Thr Ser Asn Phe Ser Ser Thr Val Ala Gly Leu Pro Arg Ile Gly 1 5 10 15 Ala Lys Arg Glu Leu Lys Phe Ala Leu Glu Gly Tyr Trp Asn Gly Ser 20 25 30 Ile Glu Gly Arg Glu Leu Ala Gln Thr Ala Arg Gln Leu Val Asn Thr 35 40 45 Ala Ser Asp Ser Leu Ser Gly Leu Asp Ser Val Pro Phe Ala Gly Arg 50 55 60 Ser Tyr Tyr Asp Ala Met Leu Asp Thr Ala Ala Ile Leu Gly Val Leu 65 70 75 80 Pro Glu Arg Phe Asp Asp Ile Ala Asp His Glu Asn Asp Gly Leu Pro 85 90 95 Leu Trp Ile Asp Arg Tyr Phe Gly Ala Ala Arg Gly Thr Glu Thr Leu 100 105 110 Pro Ala Gln Ala Met Thr Lys Trp Phe Asp Thr Asn Tyr His Tyr Leu 115 120 125 Val Pro Glu Leu Ser Ala Asp Thr Arg Phe Val Leu Asp Ala Ser Ala 130 135 140 Leu Ile Glu Asp Leu Arg Cys Gln Gln Val Arg Gly Val Asn Ala Arg 145 150 155 160 Pro Val Leu Val Gly Pro Leu Thr Phe Leu Ser Leu Ala Arg Thr Thr 165 170 175 Asp Gly Ser Asn Pro Leu Asp His Leu Pro Ala Leu Phe Glu Val Tyr 180 185 190 Glu Arg Leu Ile Lys Ser Phe Asp Thr Glu Trp Val Gln Ile Asp Glu 195 200 205 Pro Ala Leu Val Thr Asp Val Ala Pro Glu Val Leu Glu Gln Val Arg 210 215 220 Ala Gly Tyr Thr Thr Leu Ala Lys Arg Asp Gly Val Phe Val Asn Thr 225 230 235 240 Tyr Phe Gly Ser Gly Asp Gln Ala Leu Asn Thr Leu Ala Gly Ile Gly 245 250 255 Leu Gly Ala Ile Gly Val Asp Leu Val Thr His Gly Val Thr Glu Leu 260 265 270 Ala Ala Trp Lys Gly Glu Glu Leu Leu Val Ala Gly Ile Val Asp Gly 275 280 285 Arg Asn Ile Trp Arg Thr Asp Leu Cys Ala Ala Leu Ala Ser Leu Lys 290 295 300 Arg Leu Ala Ala Arg Gly Pro Ile Ala Val Ser Thr Ser Cys Ser Leu 305 310 315 320 Leu His Val Pro Tyr Thr Leu Glu Ala Glu Asn Ile Glu Pro Glu Val 325 330 335 Arg Asp Trp Leu Ala Phe Gly Ser Glu Lys Ile Thr Glu Val Lys Leu 340 345 350 Leu Ala Asp Ala Leu Ala Gly Asn Ile Asp Ala Ala Ala Phe Asp Ala 355 360 365 Ala Ser Ala Ala Ile Ala Ser Arg Arg Thr Ser Pro Arg Thr Ala Pro 370 375 380 Ile Thr Gln Glu Leu Pro Gly Arg Ser Arg Gly Ser Phe Asp Thr Arg 385 390 395 400 Val Thr Leu Gln Glu Lys Ser Leu Glu Leu Pro Ala Leu Pro Thr Thr 405 410 415 Thr Ile Gly Ser Phe Pro Gln Thr Pro Ser Ile Arg Ser Ala Arg Ala 420 425 430 Arg Leu Arg Lys Glu Ser Ile Thr Leu Glu Gln Tyr Glu Glu Ala Met 435 440 445 Arg Glu Glu Ile Asp Leu Val Ile Ala Lys Gln Glu Glu Leu Gly Leu 450 455 460 Asp Val Leu Val His Gly Glu Pro Glu Arg Asn Asp Met Val Gln Tyr 465 470 475 480 Phe Ser Glu Leu Leu Asp Gly Phe Leu Ser Thr Ala Asn Gly Trp Val 485 490 495 Gln Ser Tyr Gly Ser Arg Cys Val Arg Pro Pro Val Leu Phe Gly Asn 500 505 510 Val Ser Arg Pro Ala Pro Met Thr Val Lys Trp Phe Gln Tyr Ala Gln 515 520 525 Ser Leu Thr Gln Lys His Val Lys Gly Met Leu Thr Gly Pro Val Thr 530 535 540 Ile Leu Ala Trp Ser Phe Val Arg Asp Asp Gln Pro Leu Ala Thr Thr 545 550 555 560 Ala Asp Gln Val Ala Leu Ala Leu Arg Asp Glu Ile Asn Asp Leu Ile 565 570 575 Glu Ala Gly Ala Lys Ile Ile Gln Val Asp Glu Pro Ala Ile Arg Glu 580 585 590 Leu Leu Pro Ala Thr Arg Arg Arg 595 600 <210> 759 <211> 603 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(580) <223> FRXA02086 <400> 759 gatgatcagc cgctggctac cactgctgac caggttgcac tggcactgcg cgatgaaatt 60 aacgatctca tcgaggctgg cgcgaagatc atccaggtgg atg agc ctg cga ttc 115 Met Ser Leu Arg Phe 1 5 gtg aac tgt tgc ccg cta cga gac gtc gat aag cct gcc tac ctg cag 163 Val Asn Cys Cys Pro Leu Arg Asp Val Asp Lys Pro Ala Tyr Leu Gln 10 15 20 tgg tcc gtg gac tcc ttc cgc ctg gcg act gcc ggc gca ccc gac gac 211 Trp Ser Val Asp Ser Phe Arg Leu Ala Thr Ala Gly Ala Pro Asp Asp 25 30 35 gtc caa atc cac acc cac atg tgc tac tcc gag ttc aac gaa gtg atc 259 Val Gln Ile His Thr His Met Cys Tyr Ser Glu Phe Asn Glu Val Ile 40 45 50 tcc tcg gtc atc gcg ttg gat gcc gat gtc acc acc atc gaa gca gca 307 Ser Ser Val Ile Ala Leu Asp Ala Asp Val Thr Thr Ile Glu Ala Ala 55 60 65 cgt tcc gac atg cag gtc ctc gct gct ctg aaa tct tcc ggc ttc gag 355 Arg Ser Asp Met Gln Val Leu Ala Ala Leu Lys Ser Ser Gly Phe Glu 70 75 80 85 ctc ggc gtc gga cct ggt gtg tgg gat atc cac tcc ccg cgc gtt cct 403 Leu Gly Val Gly Pro Gly Val Trp Asp Ile His Ser Pro Arg Val Pro 90 95 100 tcc gcg cag aaa gtg gac ggt ctc ctc gag gct gca ctg cag tcc gtg 451 Ser Ala Gln Lys Val Asp Gly Leu Leu Glu Ala Ala Leu Gln Ser Val 105 110 115 gat cct cgc cag ctg tgg gtc aac cca gac tgt ggt ctg aag acc cgt 499 Asp Pro Arg Gln Leu Trp Val Asn Pro Asp Cys Gly Leu Lys Thr Arg 120 125 130 gga tgg cca gaa gtg gaa gct tcc cta aag gtt ctc gtt gag tcc gct 547 Gly Trp Pro Glu Val Glu Ala Ser Leu Lys Val Leu Val Glu Ser Ala 135 140 145 aag cag gct cgt gag aaa atc gga gca act atc taaattgggt taccgctagg 600 Lys Gln Ala Arg Glu Lys Ile Gly Ala Thr Ile 150 155 160 aac 603 <210> 760 <211> 160 <212> PRT <213> Corynebacterium glutamicum <400> 760 Met Ser Leu Arg Phe Val Asn Cys Cys Pro Leu Arg Asp Val Asp Lys 1 5 10 15 Pro Ala Tyr Leu Gln Trp Ser Val Asp Ser Phe Arg Leu Ala Thr Ala 20 25 30 Gly Ala Pro Asp Asp Val Gln Ile His Thr His Met Cys Tyr Ser Glu 35 40 45 Phe Asn Glu Val Ile Ser Ser Val Ile Ala Leu Asp Ala Asp Val Thr 50 55 60 Thr Ile Glu Ala Ala Arg Ser Asp Met Gln Val Leu Ala Ala Leu Lys 65 70 75 80 Ser Ser Gly Phe Glu Leu Gly Val Gly Pro Gly Val Trp Asp Ile His 85 90 95 Ser Pro Arg Val Pro Ser Ala Gln Lys Val Asp Gly Leu Leu Glu Ala 100 105 110 Ala Leu Gln Ser Val Asp Pro Arg Gln Leu Trp Val Asn Pro Asp Cys 115 120 125 Gly Leu Lys Thr Arg Gly Trp Pro Glu Val Glu Ala Ser Leu Lys Val 130 135 140 Leu Val Glu Ser Ala Lys Gln Ala Arg Glu Lys Ile Gly Ala Thr Ile 145 150 155 160 <210> 761 <211> 1326 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1303) <223> RXN02648 <400> 761 atgaataaaa ttccgggtgc agtgaccgta ggtgaggtaa acgcggttag agtcgaatga 60 gagtttgata ctttctttcg acttttagat tggattttca atg agc cag aac cgc 115 Met Ser Gln Asn Arg 1 5 atc agg acc act cac gtt ggt tcc ttg ccc cgt acc cca gag cta ctt 163 Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg Thr Pro Glu Leu Leu 10 15 20 gat gca aac atc aag cgt tct aac ggt gag att ggg gag gag gaa ttc 211 Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile Gly Glu Glu Glu Phe 25 30 35 ttc cag att ctg cag tct tct gta gat gac gtg atc aag cgc cag gtt 259 Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val Ile Lys Arg Gln Val 40 45 50 gac ctg ggt atc gac atc ctt aac gag ggc gaa tac ggc cac gtc acc 307 Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu Tyr Gly His Val Thr 55 60 65 tcc ggt gca gtt gac ttc ggt gca tgg tgg aac tac tcc ttc acc cgc 355 Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn Tyr Ser Phe Thr Arg 70 75 80 85 ctg ggc gga ctg acc atg acc gat acc gac cgt tgg gca agc cag gaa 403 Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg Trp Ala Ser Gln Glu 90 95 100 gca gtg cgt tcc acc cct ggc aac atc gag ctg acc agc ttc tct gat 451 Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu Thr Ser Phe Ser Asp 105 110 115 cgt cgc gac cgc gca ttg ttc agc gaa gca tac gag gat cca gta tct 499 Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr Glu Asp Pro Val Ser 120 125 130 ggc atc ttc acc ggt cgc gct tct gtg ggc aac cca gag ttc acc gga 547 Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn Pro Glu Phe Thr Gly 135 140 145 cct att acc tac att ggc cag gaa gaa act cag acg gat gtt gat ctg 595 Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln Thr Asp Val Asp Leu 150 155 160 165 ctg aag aag ggc atg aac gca gcg gga gct acc gac ggc ttc gtt gca 643 Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr Asp Gly Phe Val Ala 170 175 180 gca cta tcc cca gga tct gca gct cga ttg acc aac aag ttc tac gac 691 Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr Asn Lys Phe Tyr Asp 185 190 195 act gat gaa gaa gtc gtc gca gca tgt gct gat gcg ctt tcc cag gaa 739 Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp Ala Leu Ser Gln Glu 200 205 210 tac aag atc atc acc gat gca ggt ctg acc gtt cag ctc gac gca ccg 787 Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val Gln Leu Asp Ala Pro 215 220 225 gac ttg gca gaa gca tgg gat cag atc aac cca gag cca agc gtg aag 835 Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro Ser Val Lys 230 235 240 245 gat tac ttg gac tgg atc ggt aca cgc atc gat gcc atc aac agt gca 883 Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile Asn Ser Ala 250 255 260 gtg aag ggc ctt cca aag gaa cag acc cgc ctg cac atc tgc tgg ggc 931 Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile Cys Trp Gly 265 270 275 tct tgg cac gga cca cac gtc act gac atc cca ttc ggt gac atc att 979 Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly Asp Ile Ile 280 285 290 ggt gag atc ctg cgc gca gag gtc ggt ggc ttc tcc ttc gaa ggc gca 1027 Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe Glu Gly Ala 295 300 305 tct cct cgt cac gca cac gag tgg cgt gta tgg gaa gaa aac aag ctt 1075 Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu Asn Lys Leu 310 315 320 325 cct gaa ggc tct gtt atc tac cct ggt gtt gtg tct cac tcc atc aac 1123 Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His Ser Ile Asn 330 335 340 gct gtg gag cac cca cgc ctg gtt gct gat cgt atc gtt cag ttc gcc 1171 Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val Gln Phe Ala 345 350 355 aag ctt gtt ggc cct gag aac gtc att gcg tcc act gac tgt ggt ctg 1219 Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp Cys Gly Leu 360 365 370 ggc gga cgt ctg cat tcc cag atc gca tgg gca aag ctg gag tcc cta 1267 Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu Glu Ser Leu 375 380 385 gta gag ggc gct cgc att gca tca aag gaa ctg ttc taagctagac 1313 Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 390 395 400 aacgagggtt gct 1326 <210> 762 <211> 401 <212> PRT <213> Corynebacterium glutamicum <400> 762 Met Ser Gln Asn Arg Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg 1 5 10 15 Thr Pro Glu Leu Leu Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile 20 25 30 Gly Glu Glu Glu Phe Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val 35 40 45 Ile Lys Arg Gln Val Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu 50 55 60 Tyr Gly His Val Thr Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn 65 70 75 80 Tyr Ser Phe Thr Arg Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg 85 90 95 Trp Ala Ser Gln Glu Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu 100 105 110 Thr Ser Phe Ser Asp Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr 115 120 125 Glu Asp Pro Val Ser Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn 130 135 140 Pro Glu Phe Thr Gly Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln 145 150 155 160 Thr Asp Val Asp Leu Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr 165 170 175 Asp Gly Phe Val Ala Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr 180 185 190 Asn Lys Phe Tyr Asp Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp 195 200 205 Ala Leu Ser Gln Glu Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val 210 215 220 Gln Leu Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro 225 230 235 240 Glu Pro Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp 245 250 255 Ala Ile Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu 260 265 270 His Ile Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro 275 280 285 Phe Gly Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe 290 295 300 Ser Phe Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp 305 310 315 320 Glu Glu Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val 325 330 335 Ser His Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg 340 345 350 Ile Val Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser 355 360 365 Thr Asp Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala 370 375 380 Lys Leu Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu 385 390 395 400 Phe <210> 763 <211> 548 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(525) <223> FRXA02648 <400> 763 gac gca ccg gac ttg gca gaa gca tgg gat cag atc aac cca gag cca 48 Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro 1 5 10 15 agc gtg aag gat tac ttg gac tgg atc ggt aca cgc atc gat gcc atc 96 Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile 20 25 30 aac agt gca gtg aag ggc ctt cca aag gaa cag acc cgc ctg cac atc 144 Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile 35 40 45 tgc tgg ggc tct tgg cac gga cca cac gtc act gac atc cca ttc ggt 192 Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly 50 55 60 gac atc att ggt gag atc ctg cgc gca gag gtc ggt ggc ttc tcc ttc 240 Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe 65 70 75 80 gaa ggc gca tct cct cgt cac gca cac gag tgg cgt gta tgg gaa gaa 288 Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu 85 90 95 aac aag ctt cct gaa ggc tct gtt atc tac cct ggt gtt gtg tct cac 336 Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His 100 105 110 tcc atc aac gct gtg gag cac cca cgc ctg gtt gct gat cgt atc gtt 384 Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val 115 120 125 cag ttc gcc aag ctt gtt ggc cct gag aac gtc att gcg tcc act gac 432 Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp 130 135 140 tgt ggt ctg ggc gga cgt ctg cat tcc cag atc gca tgg gca aag ctg 480 Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu 145 150 155 160 gag tcc cta gta gag ggc gct cgc att gca tca aag gaa ctg ttc 525 Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 165 170 175 taagctagac aacgagggtt gct 548 <210> 764 <211> 175 <212> PRT <213> Corynebacterium glutamicum <400> 764 Asp Ala Pro Asp Leu Ala Glu Ala Trp Asp Gln Ile Asn Pro Glu Pro 1 5 10 15 Ser Val Lys Asp Tyr Leu Asp Trp Ile Gly Thr Arg Ile Asp Ala Ile 20 25 30 Asn Ser Ala Val Lys Gly Leu Pro Lys Glu Gln Thr Arg Leu His Ile 35 40 45 Cys Trp Gly Ser Trp His Gly Pro His Val Thr Asp Ile Pro Phe Gly 50 55 60 Asp Ile Ile Gly Glu Ile Leu Arg Ala Glu Val Gly Gly Phe Ser Phe 65 70 75 80 Glu Gly Ala Ser Pro Arg His Ala His Glu Trp Arg Val Trp Glu Glu 85 90 95 Asn Lys Leu Pro Glu Gly Ser Val Ile Tyr Pro Gly Val Val Ser His 100 105 110 Ser Ile Asn Ala Val Glu His Pro Arg Leu Val Ala Asp Arg Ile Val 115 120 125 Gln Phe Ala Lys Leu Val Gly Pro Glu Asn Val Ile Ala Ser Thr Asp 130 135 140 Cys Gly Leu Gly Gly Arg Leu His Ser Gln Ile Ala Trp Ala Lys Leu 145 150 155 160 Glu Ser Leu Val Glu Gly Ala Arg Ile Ala Ser Lys Glu Leu Phe 165 170 175 <210> 765 <211> 784 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(784) <223> FRXA02658 <400> 765 atgaataaaa ttccgggtgc agtgaccgta ggtgaggtaa acgcggttag agtcgaatga 60 gagtttgata ctttctttcg acttttagat tggattttca atg agc cag aac cgc 115 Met Ser Gln Asn Arg 1 5 atc agg acc act cac gtt ggt tcc ttg ccc cgt acc cca gag cta ctt 163 Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg Thr Pro Glu Leu Leu 10 15 20 gat gca aac atc aag cgt tct aac ggt gag att ggg gag gag gaa ttc 211 Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile Gly Glu Glu Glu Phe 25 30 35 ttc cag att ctg cag tct tct gta gat gac gtg atc aag cgc cag gtt 259 Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val Ile Lys Arg Gln Val 40 45 50 gac ctg ggt atc gac atc ctt aac gag ggc gaa tac ggc cac gtc acc 307 Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu Tyr Gly His Val Thr 55 60 65 tcc ggt gca gtt gac ttc ggt gca tgg tgg aac tac tcc ttc acc cgc 355 Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn Tyr Ser Phe Thr Arg 70 75 80 85 ctg ggc gga ctg acc atg acc gat acc gac cgt tgg gca agc cag gaa 403 Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg Trp Ala Ser Gln Glu 90 95 100 gca gtg cgt tcc acc cct ggc aac atc gag ctg acc agc ttc tct gat 451 Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu Thr Ser Phe Ser Asp 105 110 115 cgt cgc gac cgc gca ttg ttc agc gaa gca tac gag gat cca gta tct 499 Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr Glu Asp Pro Val Ser 120 125 130 ggc atc ttc acc ggt cgc gct tct gtg ggc aac cca gag ttc acc gga 547 Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn Pro Glu Phe Thr Gly 135 140 145 cct att acc tac att ggc cag gaa gaa act cag acg gat gtt gat ctg 595 Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln Thr Asp Val Asp Leu 150 155 160 165 ctg aag aag ggc atg aac gca gcg gga gct acc gac ggc ttc gtt gca 643 Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr Asp Gly Phe Val Ala 170 175 180 gca cta tcc cca gga tct gca gct cga ttg acc aac aag ttc tac gac 691 Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr Asn Lys Phe Tyr Asp 185 190 195 act gat gaa gaa gtc gtc gca gca tgt gct gat gcg ctt tcc cag gaa 739 Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp Ala Leu Ser Gln Glu 200 205 210 tac aag atc atc acc gat gca ggt ctg acc gtt cag ctc gac gca 784 Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val Gln Leu Asp Ala 215 220 225 <210> 766 <211> 228 <212> PRT <213> Corynebacterium glutamicum <400> 766 Met Ser Gln Asn Arg Ile Arg Thr Thr His Val Gly Ser Leu Pro Arg 1 5 10 15 Thr Pro Glu Leu Leu Asp Ala Asn Ile Lys Arg Ser Asn Gly Glu Ile 20 25 30 Gly Glu Glu Glu Phe Phe Gln Ile Leu Gln Ser Ser Val Asp Asp Val 35 40 45 Ile Lys Arg Gln Val Asp Leu Gly Ile Asp Ile Leu Asn Glu Gly Glu 50 55 60 Tyr Gly His Val Thr Ser Gly Ala Val Asp Phe Gly Ala Trp Trp Asn 65 70 75 80 Tyr Ser Phe Thr Arg Leu Gly Gly Leu Thr Met Thr Asp Thr Asp Arg 85 90 95 Trp Ala Ser Gln Glu Ala Val Arg Ser Thr Pro Gly Asn Ile Glu Leu 100 105 110 Thr Ser Phe Ser Asp Arg Arg Asp Arg Ala Leu Phe Ser Glu Ala Tyr 115 120 125 Glu Asp Pro Val Ser Gly Ile Phe Thr Gly Arg Ala Ser Val Gly Asn 130 135 140 Pro Glu Phe Thr Gly Pro Ile Thr Tyr Ile Gly Gln Glu Glu Thr Gln 145 150 155 160 Thr Asp Val Asp Leu Leu Lys Lys Gly Met Asn Ala Ala Gly Ala Thr 165 170 175 Asp Gly Phe Val Ala Ala Leu Ser Pro Gly Ser Ala Ala Arg Leu Thr 180 185 190 Asn Lys Phe Tyr Asp Thr Asp Glu Glu Val Val Ala Ala Cys Ala Asp 195 200 205 Ala Leu Ser Gln Glu Tyr Lys Ile Ile Thr Asp Ala Gly Leu Thr Val 210 215 220 Gln Leu Asp Ala 225 <210> 767 <211> 513 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(490) <223> RXA01516 <400> 767 tctgcacata tgggagcatg gggtgtgcgc gtgcacgatg tcccagtatc aagggacgct 60 gttgatgttg ccgcattgtg gcgaagtgga ggaactcacc atg gct gat cgt att 115 Met Ala Asp Arg Ile 1 5 gaa ctt aaa ggc ctt gaa tgc ttc gga cac cac ggt gtg ttc gac ttt 163 Glu Leu Lys Gly Leu Glu Cys Phe Gly His His Gly Val Phe Asp Phe 10 15 20 gaa aaa gag caa ggc cag ccc ttc att gtg gat gtc acc tgc tgg atg 211 Glu Lys Glu Gln Gly Gln Pro Phe Ile Val Asp Val Thr Cys Trp Met 25 30 35 gat ttc gat gcc gca ggt gcc agc gat gac ctt tcc gac acc gta gat 259 Asp Phe Asp Ala Ala Gly Ala Ser Asp Asp Leu Ser Asp Thr Val Asp 40 45 50 tac ggc gcg ttg gca ttg ttg gtt gct gaa atc gtg gaa ggc cca tcc 307 Tyr Gly Ala Leu Ala Leu Leu Val Ala Glu Ile Val Glu Gly Pro Ser 55 60 65 agg gat ttg atc gag acg gtg gcc acg gaa tct gcg gat gct gtg atg 355 Arg Asp Leu Ile Glu Thr Val Ala Thr Glu Ser Ala Asp Ala Val Met 70 75 80 85 gct aaa ttt gat gcg ctt cat gcg gtg gaa gta acc atc cat aag ccc 403 Ala Lys Phe Asp Ala Leu His Ala Val Glu Val Thr Ile His Lys Pro 90 95 100 aaa gca ccg atc cca cgt act ttt gct gac gtc gcg gtg gtt gcc cga 451 Lys Ala Pro Ile Pro Arg Thr Phe Ala Asp Val Ala Val Val Ala Arg 105 110 115 cgt tcc agg aaa tcc atg gct gct gga agg agc aac gcc taatgcatgc 500 Arg Ser Arg Lys Ser Met Ala Ala Gly Arg Ser Asn Ala 120 125 130 agttttgtcc atc 513 <210> 768 <211> 130 <212> PRT <213> Corynebacterium glutamicum <400> 768 Met Ala Asp Arg Ile Glu Leu Lys Gly Leu Glu Cys Phe Gly His His 1 5 10 15 Gly Val Phe Asp Phe Glu Lys Glu Gln Gly Gln Pro Phe Ile Val Asp 20 25 30 Val Thr Cys Trp Met Asp Phe Asp Ala Ala Gly Ala Ser Asp Asp Leu 35 40 45 Ser Asp Thr Val Asp Tyr Gly Ala Leu Ala Leu Leu Val Ala Glu Ile 50 55 60 Val Glu Gly Pro Ser Arg Asp Leu Ile Glu Thr Val Ala Thr Glu Ser 65 70 75 80 Ala Asp Ala Val Met Ala Lys Phe Asp Ala Leu His Ala Val Glu Val 85 90 95 Thr Ile His Lys Pro Lys Ala Pro Ile Pro Arg Thr Phe Ala Asp Val 100 105 110 Ala Val Val Ala Arg Arg Ser Arg Lys Ser Met Ala Ala Gly Arg Ser 115 120 125 Asn Ala 130 <210> 769 <211> 975 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(952) <223> RXA01515 <400> 769 taagcctggt gctgtgacca cgacgtctgc ggtgcgcggc ggttttaaga acaacgctgc 60 ctcccgcgct gaggtgttct ccctgattcg ggggcactaa atg aac gta tcc tct 115 Met Asn Val Ser Ser 1 5 ttg acc atc ccg gga cgc tgt ttg gtc atg gga att gtc aat gtc act 163 Leu Thr Ile Pro Gly Arg Cys Leu Val Met Gly Ile Val Asn Val Thr 10 15 20 gag gat tcc ttt tcg gac ggt ggc aag tac att gac gtt gat cag gcg 211 Glu Asp Ser Phe Ser Asp Gly Gly Lys Tyr Ile Asp Val Asp Gln Ala 25 30 35 atc gcg cat gcc aag gaa ttg gtg gct gct ggc gcc gac atg att gat 259 Ile Ala His Ala Lys Glu Leu Val Ala Ala Gly Ala Asp Met Ile Asp 40 45 50 gtc ggc ggc gag tcc acc cgg cct ggg gca gtg cgc gtc gac gcg tcc 307 Val Gly Gly Glu Ser Thr Arg Pro Gly Ala Val Arg Val Asp Ala Ser 55 60 65 gtg gaa cgg gac cgg gtt gtg ccg gtc att aag gcg ctt cac gac gcc 355 Val Glu Arg Asp Arg Val Val Pro Val Ile Lys Ala Leu His Asp Ala 70 75 80 85 ggc atc cac act tcc gta gac acc atg cgg gcc tcc gtg gcg cag gct 403 Gly Ile His Thr Ser Val Asp Thr Met Arg Ala Ser Val Ala Gln Ala 90 95 100 gcc gcg ggc gct ggc gtc tcc atg atc aac gac gtc tct ggc ggt ttg 451 Ala Ala Gly Ala Gly Val Ser Met Ile Asn Asp Val Ser Gly Gly Leu 105 110 115 gct gat cct gag atg ttt tct gtc atg gcg gaa gcg caa att ccc gtg 499 Ala Asp Pro Glu Met Phe Ser Val Met Ala Glu Ala Gln Ile Pro Val 120 125 130 tgt ttg atg cac tgg cgc acc ctc caa ttc ggt gat gcc gca ggt cag 547 Cys Leu Met His Trp Arg Thr Leu Gln Phe Gly Asp Ala Ala Gly Gln 135 140 145 gca gat cac ggt gga gac gtt gta gcc gat gtg cac gca gtg ctt gat 595 Ala Asp His Gly Gly Asp Val Val Ala Asp Val His Ala Val Leu Asp 150 155 160 165 gat ctt gtc gcc cgc gcc acc gct gct ggt gtg gcc gaa aac cag atc 643 Asp Leu Val Ala Arg Ala Thr Ala Ala Gly Val Ala Glu Asn Gln Ile 170 175 180 gtg ctt gat cca ggt ttg ggt ttt gcc aaa tca cgt gaa gac aac tgg 691 Val Leu Asp Pro Gly Leu Gly Phe Ala Lys Ser Arg Glu Asp Asn Trp 185 190 195 cgt ttg ctg caa gca ctg ccc gag ttt att tct gga cct ttc ccc atc 739 Arg Leu Leu Gln Ala Leu Pro Glu Phe Ile Ser Gly Pro Phe Pro Ile 200 205 210 ctg gtg gga gca tcc cgg aag cga ttc ctg gct ggc gtg cgc aaa gac 787 Leu Val Gly Ala Ser Arg Lys Arg Phe Leu Ala Gly Val Arg Lys Asp 215 220 225 cgt ggc cta gat gtc acc ccc att gat gcc gac cca gca acc gca gcg 835 Arg Gly Leu Asp Val Thr Pro Ile Asp Ala Asp Pro Ala Thr Ala Ala 230 235 240 245 gtg acc gca gtg tct gca cat atg gga gca tgg ggt gtg cgc gtg cac 883 Val Thr Ala Val Ser Ala His Met Gly Ala Trp Gly Val Arg Val His 250 255 260 gat gtc cca gta tca agg gac gct gtt gat gtt gcc gca ttg tgg cga 931 Asp Val Pro Val Ser Arg Asp Ala Val Asp Val Ala Ala Leu Trp Arg 265 270 275 agt gga gga act cac cat ggc tgatcgtatt gaacttaaag gcc 975 Ser Gly Gly Thr His His Gly 280 <210> 770 <211> 284 <212> PRT <213> Corynebacterium glutamicum <400> 770 Met Asn Val Ser Ser Leu Thr Ile Pro Gly Arg Cys Leu Val Met Gly 1 5 10 15 Ile Val Asn Val Thr Glu Asp Ser Phe Ser Asp Gly Gly Lys Tyr Ile 20 25 30 Asp Val Asp Gln Ala Ile Ala His Ala Lys Glu Leu Val Ala Ala Gly 35 40 45 Ala Asp Met Ile Asp Val Gly Gly Glu Ser Thr Arg Pro Gly Ala Val 50 55 60 Arg Val Asp Ala Ser Val Glu Arg Asp Arg Val Val Pro Val Ile Lys 65 70 75 80 Ala Leu His Asp Ala Gly Ile His Thr Ser Val Asp Thr Met Arg Ala 85 90 95 Ser Val Ala Gln Ala Ala Ala Gly Ala Gly Val Ser Met Ile Asn Asp 100 105 110 Val Ser Gly Gly Leu Ala Asp Pro Glu Met Phe Ser Val Met Ala Glu 115 120 125 Ala Gln Ile Pro Val Cys Leu Met His Trp Arg Thr Leu Gln Phe Gly 130 135 140 Asp Ala Ala Gly Gln Ala Asp His Gly Gly Asp Val Val Ala Asp Val 145 150 155 160 His Ala Val Leu Asp Asp Leu Val Ala Arg Ala Thr Ala Ala Gly Val 165 170 175 Ala Glu Asn Gln Ile Val Leu Asp Pro Gly Leu Gly Phe Ala Lys Ser 180 185 190 Arg Glu Asp Asn Trp Arg Leu Leu Gln Ala Leu Pro Glu Phe Ile Ser 195 200 205 Gly Pro Phe Pro Ile Leu Val Gly Ala Ser Arg Lys Arg Phe Leu Ala 210 215 220 Gly Val Arg Lys Asp Arg Gly Leu Asp Val Thr Pro Ile Asp Ala Asp 225 230 235 240 Pro Ala Thr Ala Ala Val Thr Ala Val Ser Ala His Met Gly Ala Trp 245 250 255 Gly Val Arg Val His Asp Val Pro Val Ser Arg Asp Ala Val Asp Val 260 265 270 Ala Ala Leu Trp Arg Ser Gly Gly Thr His His Gly 275 280 <210> 771 <211> 859 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(859) <223> RXA02024 <400> 771 cactgatgac ctggatcagg ccgtcaaatt catcgtcgat gcacacgctg gattggacgt 60 agcgcgtctc cacaattaag cagtggctac attaggtgtt atg agt tct ttg ccg 115 Met Ser Ser Leu Pro 1 5 gtc atc atg gcc atc gtc aat cgc acc ccg gat tct ttc tat gac aag 163 Val Ile Met Ala Ile Val Asn Arg Thr Pro Asp Ser Phe Tyr Asp Lys 10 15 20 ggt gcg aca ttt gag gac acc gct gcg cta aac agg gca gcg gag gtc 211 Gly Ala Thr Phe Glu Asp Thr Ala Ala Leu Asn Arg Ala Ala Glu Val 25 30 35 att gaa caa ggc gcc ggc att gtc gat atc ggt ggg gtg aaa gcc ggc 259 Ile Glu Gln Gly Ala Gly Ile Val Asp Ile Gly Gly Val Lys Ala Gly 40 45 50 ccg ggg gat ttc gtg tcg gcg gag gaa gag atc gac cgc gtg gtg cca 307 Pro Gly Asp Phe Val Ser Ala Glu Glu Glu Ile Asp Arg Val Val Pro 55 60 65 atc atc gct gcg gtg cga gaa cgt ttt cct gac att gat att tct gtt 355 Ile Ile Ala Ala Val Arg Glu Arg Phe Pro Asp Ile Asp Ile Ser Val 70 75 80 85 gat acc tgg cgg gcg tcg gtg gct gat gtc gca gtg gcg cat gga gca 403 Asp Thr Trp Arg Ala Ser Val Ala Asp Val Ala Val Ala His Gly Ala 90 95 100 acg ctg atc aat gac act tgg gcc ggc cat gat cat gag ttg gtg cag 451 Thr Leu Ile Asn Asp Thr Trp Ala Gly His Asp His Glu Leu Val Gln 105 110 115 gta gca ggg cag cac aag gtg ggt tat gtc tgc tcg cac acc ggc ggg 499 Val Ala Gly Gln His Lys Val Gly Tyr Val Cys Ser His Thr Gly Gly 120 125 130 gtg att cca aga acg cga cca tat cgg gtg cat ttc gat gac atc gtg 547 Val Ile Pro Arg Thr Arg Pro Tyr Arg Val His Phe Asp Asp Ile Val 135 140 145 gcc gat gta att acg gag acc acc aaa ttg gca gag caa gct gtt cgt 595 Ala Asp Val Ile Thr Glu Thr Thr Lys Leu Ala Glu Gln Ala Val Arg 150 155 160 165 gcc ggg gtg cca gag gaa cgg gtg ttt att gat ccc acc cat gat ttc 643 Ala Gly Val Pro Glu Glu Arg Val Phe Ile Asp Pro Thr His Asp Phe 170 175 180 ggg aaa aac acc ttc cac gga ctg gag ctt tta cga cgg atc gat gag 691 Gly Lys Asn Thr Phe His Gly Leu Glu Leu Leu Arg Arg Ile Asp Glu 185 190 195 gtg gtt gcc acg ggc tgg ccg gtg ctg atg gcc ttg agt aat aag gat 739 Val Val Ala Thr Gly Trp Pro Val Leu Met Ala Leu Ser Asn Lys Asp 200 205 210 ttc att ggg gaa act ttg gaa agg ggc gtc gat aag cgt gtt gct ggc 787 Phe Ile Gly Glu Thr Leu Glu Arg Gly Val Asp Lys Arg Val Ala Gly 215 220 225 acg ctt gct gcc act gcc tgg gcg gcg gcg cgc ggc gtt gcg gct ttt 835 Thr Leu Ala Ala Thr Ala Trp Ala Ala Ala Arg Gly Val Ala Ala Phe 230 235 240 245 cgc gtg cat gaa gtt gcg gaa acc 859 Arg Val His Glu Val Ala Glu Thr 250 <210> 772 <211> 253 <212> PRT <213> Corynebacterium glutamicum <400> 772 Met Ser Ser Leu Pro Val Ile Met Ala Ile Val Asn Arg Thr Pro Asp 1 5 10 15 Ser Phe Tyr Asp Lys Gly Ala Thr Phe Glu Asp Thr Ala Ala Leu Asn 20 25 30 Arg Ala Ala Glu Val Ile Glu Gln Gly Ala Gly Ile Val Asp Ile Gly 35 40 45 Gly Val Lys Ala Gly Pro Gly Asp Phe Val Ser Ala Glu Glu Glu Ile 50 55 60 Asp Arg Val Val Pro Ile Ile Ala Ala Val Arg Glu Arg Phe Pro Asp 65 70 75 80 Ile Asp Ile Ser Val Asp Thr Trp Arg Ala Ser Val Ala Asp Val Ala 85 90 95 Val Ala His Gly Ala Thr Leu Ile Asn Asp Thr Trp Ala Gly His Asp 100 105 110 His Glu Leu Val Gln Val Ala Gly Gln His Lys Val Gly Tyr Val Cys 115 120 125 Ser His Thr Gly Gly Val Ile Pro Arg Thr Arg Pro Tyr Arg Val His 130 135 140 Phe Asp Asp Ile Val Ala Asp Val Ile Thr Glu Thr Thr Lys Leu Ala 145 150 155 160 Glu Gln Ala Val Arg Ala Gly Val Pro Glu Glu Arg Val Phe Ile Asp 165 170 175 Pro Thr His Asp Phe Gly Lys Asn Thr Phe His Gly Leu Glu Leu Leu 180 185 190 Arg Arg Ile Asp Glu Val Val Ala Thr Gly Trp Pro Val Leu Met Ala 195 200 205 Leu Ser Asn Lys Asp Phe Ile Gly Glu Thr Leu Glu Arg Gly Val Asp 210 215 220 Lys Arg Val Ala Gly Thr Leu Ala Ala Thr Ala Trp Ala Ala Ala Arg 225 230 235 240 Gly Val Ala Ala Phe Arg Val His Glu Val Ala Glu Thr 245 250 <210> 773 <211> 684 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(661) <223> RXA01719 <400> 773 ccatatggtc ggtgcactgg ctggaagtgg cggtattgca ctggtgactt cgtcgattgc 60 cgaggacggt ctggttgatg ttgtgctggg gagaatgtaa atg aat atc atc att 115 Met Asn Ile Ile Ile 1 5 ctt gct ggt ggc gag ggt aaa cgc atg ggt ggg gtg gat aag gct gct 163 Leu Ala Gly Gly Glu Gly Lys Arg Met Gly Gly Val Asp Lys Ala Ala 10 15 20 gtg gcg gtg gat ggt cgc acg ctg ctg gat atc ctg ctt tca cag ctg 211 Val Ala Val Asp Gly Arg Thr Leu Leu Asp Ile Leu Leu Ser Gln Leu 25 30 35 gat cca gaa gat gac gtc gtg gtg gtt tcc ccc gcg atc atc gac gga 259 Asp Pro Glu Asp Asp Val Val Val Val Ser Pro Ala Ile Ile Asp Gly 40 45 50 atc acg act gtc tgc gag gaa cct ccg ctt ggc ggg ccg gtc gcg gga 307 Ile Thr Thr Val Cys Glu Glu Pro Pro Leu Gly Gly Pro Val Ala Gly 55 60 65 atc gag gca ggg ctg aat tct ttt gag cac gcc cat gaa ttc act gcg 355 Ile Glu Ala Gly Leu Asn Ser Phe Glu His Ala His Glu Phe Thr Ala 70 75 80 85 att ctt gcc gtg gac gcg cct tat tct gca gcg atg ctg ccc cta ctt 403 Ile Leu Ala Val Asp Ala Pro Tyr Ser Ala Ala Met Leu Pro Leu Leu 90 95 100 cag gca cag att ggc aaa gcc gat gtg gcc gta acc ctt gct gcc gat 451 Gln Ala Gln Ile Gly Lys Ala Asp Val Ala Val Thr Leu Ala Ala Asp 105 110 115 ggc tgg gta caa ccg ttg tgc gcg ctg tgg aga agt ggc agc cta gaa 499 Gly Trp Val Gln Pro Leu Cys Ala Leu Trp Arg Ser Gly Ser Leu Glu 120 125 130 gcg gtg att cac agc ctg ggc gag act aga aat cga ccg gca aaa gcg 547 Ala Val Ile His Ser Leu Gly Glu Thr Arg Asn Arg Pro Ala Lys Ala 135 140 145 tta ctg aag caa gcg gga cac att gtg gaa gtg ggt ggc gat ggc act 595 Leu Leu Lys Gln Ala Gly His Ile Val Glu Val Gly Gly Asp Gly Thr 150 155 160 165 gaa aaa gac tac gat acg gtg gct gaa ctg gag gta ttg ggc aac gta 643 Glu Lys Asp Tyr Asp Thr Val Ala Glu Leu Glu Val Leu Gly Asn Val 170 175 180 acg ctc cct aaa gcc cac tgatgagaaa cgtgagctct gct 684 Thr Leu Pro Lys Ala His 185 <210> 774 <211> 187 <212> PRT <213> Corynebacterium glutamicum <400> 774 Met Asn Ile Ile Ile Leu Ala Gly Gly Glu Gly Lys Arg Met Gly Gly 1 5 10 15 Val Asp Lys Ala Ala Val Ala Val Asp Gly Arg Thr Leu Leu Asp Ile 20 25 30 Leu Leu Ser Gln Leu Asp Pro Glu Asp Asp Val Val Val Val Ser Pro 35 40 45 Ala Ile Ile Asp Gly Ile Thr Thr Val Cys Glu Glu Pro Pro Leu Gly 50 55 60 Gly Pro Val Ala Gly Ile Glu Ala Gly Leu Asn Ser Phe Glu His Ala 65 70 75 80 His Glu Phe Thr Ala Ile Leu Ala Val Asp Ala Pro Tyr Ser Ala Ala 85 90 95 Met Leu Pro Leu Leu Gln Ala Gln Ile Gly Lys Ala Asp Val Ala Val 100 105 110 Thr Leu Ala Ala Asp Gly Trp Val Gln Pro Leu Cys Ala Leu Trp Arg 115 120 125 Ser Gly Ser Leu Glu Ala Val Ile His Ser Leu Gly Glu Thr Arg Asn 130 135 140 Arg Pro Ala Lys Ala Leu Leu Lys Gln Ala Gly His Ile Val Glu Val 145 150 155 160 Gly Gly Asp Gly Thr Glu Lys Asp Tyr Asp Thr Val Ala Glu Leu Glu 165 170 175 Val Leu Gly Asn Val Thr Leu Pro Lys Ala His 180 185 <210> 775 <211> 1332 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1309) <223> RXA01720 <400> 775 acacccgttt gagaatctca acctcttaaa acagcgcgaa ctattgattt ggcaactacc 60 ctatatattt gagtgtttat tgtcgaaaaa ggggtttcaa gtg gca cag caa cgc 115 Val Ala Gln Gln Arg 1 5 agc gtc gat gac tat ctt tcc att ttg ata gac agc gtc gca ccg ctt 163 Ser Val Asp Asp Tyr Leu Ser Ile Leu Ile Asp Ser Val Ala Pro Leu 10 15 20 ccg cca gta aaa acc cct atc ctc ggc gcg cat ccg tta agt cac ctt 211 Pro Pro Val Lys Thr Pro Ile Leu Gly Ala His Pro Leu Ser His Leu 25 30 35 gca gag gat gtt gtc gcg aca att cct atc ccg aaa ttt act aat tct 259 Ala Glu Asp Val Val Ala Thr Ile Pro Ile Pro Lys Phe Thr Asn Ser 40 45 50 gct gtt gat ggt tac gcc att ttg aaa gaa gac atc cat ggc agc ggg 307 Ala Val Asp Gly Tyr Ala Ile Leu Lys Glu Asp Ile His Gly Ser Gly 55 60 65 ccg tgg aca ttt ctt gtg ggc ggt gat act ccg gcg ggt tct gcg ccg 355 Pro Trp Thr Phe Leu Val Gly Gly Asp Thr Pro Ala Gly Ser Ala Pro 70 75 80 85 gcg agc att aat aat gga aaa gcc atc cgt gtg atg aca ggt gga ccc 403 Ala Ser Ile Asn Asn Gly Lys Ala Ile Arg Val Met Thr Gly Gly Pro 90 95 100 gtc cca tcc acc aac aag gac atg atc gtg gtt cca gtg gag ctc acc 451 Val Pro Ser Thr Asn Lys Asp Met Ile Val Val Pro Val Glu Leu Thr 105 110 115 aat gct ccg gtg gat cac tcg ctt cct aca gaa atc acg atc aat gag 499 Asn Ala Pro Val Asp His Ser Leu Pro Thr Glu Ile Thr Ile Asn Glu 120 125 130 cta cca ggt gag agg aat aat att cgc cat gct ggt gag cat ctt aaa 547 Leu Pro Gly Glu Arg Asn Asn Ile Arg His Ala Gly Glu His Leu Lys 135 140 145 gaa ggc gaa att gcg gtt gct gcg ggg acg gca ttt gat gcg ggt act 595 Glu Gly Glu Ile Ala Val Ala Ala Gly Thr Ala Phe Asp Ala Gly Thr 150 155 160 165 gtg tcg acg gtg att tca gtt ggc cat gac act gta aaa gcc cat cct 643 Val Ser Thr Val Ile Ser Val Gly His Asp Thr Val Lys Ala His Pro 170 175 180 tgc cct cgg gtt gcg gtg atc act acc ggt gat gag cta aac cag gga 691 Cys Pro Arg Val Ala Val Ile Thr Thr Gly Asp Glu Leu Asn Gln Gly 185 190 195 aat ccc tgg ggt atc cct aat tcc aat ggg ccg atg ctg gtt gcg gag 739 Asn Pro Trp Gly Ile Pro Asn Ser Asn Gly Pro Met Leu Val Ala Glu 200 205 210 cta aaa cgc gtg ggg att aag gat ccg cag cat ttc cat tcc gat gat 787 Leu Lys Arg Val Gly Ile Lys Asp Pro Gln His Phe His Ser Asp Asp 215 220 225 tct gag act gca ttg agg gag acg ctc gat aag cct gca gag gtt gcg 835 Ser Glu Thr Ala Leu Arg Glu Thr Leu Asp Lys Pro Ala Glu Val Ala 230 235 240 245 gat gtg atc atc act gtg ggt ggg atc tcg gcg ggc gcg ttc gat gtg 883 Asp Val Ile Ile Thr Val Gly Gly Ile Ser Ala Gly Ala Phe Asp Val 250 255 260 gtc aaa gcc gtg gga act aag act ggt ggt ttt gaa ttc ttc ccc att 931 Val Lys Ala Val Gly Thr Lys Thr Gly Gly Phe Glu Phe Phe Pro Ile 265 270 275 gcg atg aag ccg ggt aaa ccg caa ggt cat ggg cag tgg ggc gac gca 979 Ala Met Lys Pro Gly Lys Pro Gln Gly His Gly Gln Trp Gly Asp Ala 280 285 290 aaa gtg gtg tgt ctg ccg gga aac ccg gtg gcg gcg tgg gtt agt ttt 1027 Lys Val Val Cys Leu Pro Gly Asn Pro Val Ala Ala Trp Val Ser Phe 295 300 305 agg ctc ttt gtt gtt ccg gta att gag aga tta ggg ggt gga aag agg 1075 Arg Leu Phe Val Val Pro Val Ile Glu Arg Leu Gly Gly Gly Lys Arg 310 315 320 325 ctg gcg tcg ata agc gaa ctc cct gtg gtg gcg ctg cgc tcg aac cgg 1123 Leu Ala Ser Ile Ser Glu Leu Pro Val Val Ala Leu Arg Ser Asn Arg 330 335 340 gcg ctg aag gcg cgg gag ggc ccc gta ttg gcg ata ccg gtg gcg att 1171 Ala Leu Lys Ala Arg Glu Gly Pro Val Leu Ala Ile Pro Val Ala Ile 345 350 355 gat tgg gag aaa aga atg gca aat tct cag gca cat cga tcc cat atg 1219 Asp Trp Glu Lys Arg Met Ala Asn Ser Gln Ala His Arg Ser His Met 360 365 370 gtc ggt gca ctg gct gga agt ggc ggt att gca ctg gtg act tcg tcg 1267 Val Gly Ala Leu Ala Gly Ser Gly Gly Ile Ala Leu Val Thr Ser Ser 375 380 385 att gcc gag gac ggt ctg gtt gat gtt gtg ctg ggg aga atg 1309 Ile Ala Glu Asp Gly Leu Val Asp Val Val Leu Gly Arg Met 390 395 400 taaatgaata tcatcattct tgc 1332 <210> 776 <211> 403 <212> PRT <213> Corynebacterium glutamicum <400> 776 Val Ala Gln Gln Arg Ser Val Asp Asp Tyr Leu Ser Ile Leu Ile Asp 1 5 10 15 Ser Val Ala Pro Leu Pro Pro Val Lys Thr Pro Ile Leu Gly Ala His 20 25 30 Pro Leu Ser His Leu Ala Glu Asp Val Val Ala Thr Ile Pro Ile Pro 35 40 45 Lys Phe Thr Asn Ser Ala Val Asp Gly Tyr Ala Ile Leu Lys Glu Asp 50 55 60 Ile His Gly Ser Gly Pro Trp Thr Phe Leu Val Gly Gly Asp Thr Pro 65 70 75 80 Ala Gly Ser Ala Pro Ala Ser Ile Asn Asn Gly Lys Ala Ile Arg Val 85 90 95 Met Thr Gly Gly Pro Val Pro Ser Thr Asn Lys Asp Met Ile Val Val 100 105 110 Pro Val Glu Leu Thr Asn Ala Pro Val Asp His Ser Leu Pro Thr Glu 115 120 125 Ile Thr Ile Asn Glu Leu Pro Gly Glu Arg Asn Asn Ile Arg His Ala 130 135 140 Gly Glu His Leu Lys Glu Gly Glu Ile Ala Val Ala Ala Gly Thr Ala 145 150 155 160 Phe Asp Ala Gly Thr Val Ser Thr Val Ile Ser Val Gly His Asp Thr 165 170 175 Val Lys Ala His Pro Cys Pro Arg Val Ala Val Ile Thr Thr Gly Asp 180 185 190 Glu Leu Asn Gln Gly Asn Pro Trp Gly Ile Pro Asn Ser Asn Gly Pro 195 200 205 Met Leu Val Ala Glu Leu Lys Arg Val Gly Ile Lys Asp Pro Gln His 210 215 220 Phe His Ser Asp Asp Ser Glu Thr Ala Leu Arg Glu Thr Leu Asp Lys 225 230 235 240 Pro Ala Glu Val Ala Asp Val Ile Ile Thr Val Gly Gly Ile Ser Ala 245 250 255 Gly Ala Phe Asp Val Val Lys Ala Val Gly Thr Lys Thr Gly Gly Phe 260 265 270 Glu Phe Phe Pro Ile Ala Met Lys Pro Gly Lys Pro Gln Gly His Gly 275 280 285 Gln Trp Gly Asp Ala Lys Val Val Cys Leu Pro Gly Asn Pro Val Ala 290 295 300 Ala Trp Val Ser Phe Arg Leu Phe Val Val Pro Val Ile Glu Arg Leu 305 310 315 320 Gly Gly Gly Lys Arg Leu Ala Ser Ile Ser Glu Leu Pro Val Val Ala 325 330 335 Leu Arg Ser Asn Arg Ala Leu Lys Ala Arg Glu Gly Pro Val Leu Ala 340 345 350 Ile Pro Val Ala Ile Asp Trp Glu Lys Arg Met Ala Asn Ser Gln Ala 355 360 365 His Arg Ser His Met Val Gly Ala Leu Ala Gly Ser Gly Gly Ile Ala 370 375 380 Leu Val Thr Ser Ser Ile Ala Glu Asp Gly Leu Val Asp Val Val Leu 385 390 395 400 Gly Arg Met <210> 777 <211> 1237 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (2)..(1207) <223> RXS03223 <400> 777 t cca gag cca gtg cgt att gct att gca gag gca ctg ggt ttg atg tgc 49 Pro Glu Pro Val Arg Ile Ala Ile Ala Glu Ala Leu Gly Leu Met Cys 1 5 10 15 gcg gaa gag gtt caa gct agt cgt gct ttg ccg ggt ttc gcg caa gca 97 Ala Glu Glu Val Gln Ala Ser Arg Ala Leu Pro Gly Phe Ala Gln Ala 20 25 30 gcg att gat ggt tat gcg gtt cga gca gtc gat gtc ggc ggc gag aag 145 Ala Ile Asp Gly Tyr Ala Val Arg Ala Val Asp Val Gly Gly Glu Lys 35 40 45 tcg ttt agc cag caa ctg ccg gtt gct cct ccg gaa aaa tcc ctg ccc 193 Ser Phe Ser Gln Gln Leu Pro Val Ala Pro Pro Glu Lys Ser Leu Pro 50 55 60 gtg gtg ggt gaa gta gct gcg ggt tct cag cag ccg ttg cgc ctg cag 241 Val Val Gly Glu Val Ala Ala Gly Ser Gln Gln Pro Leu Arg Leu Gln 65 70 75 80 cct aaa caa gca gtc atg gtc cac acc ggt gcg cca ctg ccg atg ctt 289 Pro Lys Gln Ala Val Met Val His Thr Gly Ala Pro Leu Pro Met Leu 85 90 95 gcg gat gcg gtg ctg ccc atg gcg tgg tca gat cgt ggc cgc aaa cga 337 Ala Asp Ala Val Leu Pro Met Ala Trp Ser Asp Arg Gly Arg Lys Arg 100 105 110 gta acc gcg cag cga cct gtg cgc tct ggc gag ttt gtg cgc aaa gaa 385 Val Thr Ala Gln Arg Pro Val Arg Ser Gly Glu Phe Val Arg Lys Glu 115 120 125 ggc gat gac atc caa ccg gga gac atc gca gtc agc gcc ggc gcg gtc 433 Gly Asp Asp Ile Gln Pro Gly Asp Ile Ala Val Ser Ala Gly Ala Val 130 135 140 tta ggc cct gcc caa att ggt ttg ctc gca gct gtt ggt cgc tcc aaa 481 Leu Gly Pro Ala Gln Ile Gly Leu Leu Ala Ala Val Gly Arg Ser Lys 145 150 155 160 gtg ttg gtg tac cca cgc cca cgc atg tcg gtt atc tcc gta ggc gct 529 Val Leu Val Tyr Pro Arg Pro Arg Met Ser Val Ile Ser Val Gly Ala 165 170 175 gaa ctt gtt gat att gat cgc cag cca ggc ctc ggc cag gtt tat gat 577 Glu Leu Val Asp Ile Asp Arg Gln Pro Gly Leu Gly Gln Val Tyr Asp 180 185 190 gtc aat tcc tat tct ctg gct gcc gcc ggt agg gaa gcg ggc gca gat 625 Val Asn Ser Tyr Ser Leu Ala Ala Ala Gly Arg Glu Ala Gly Ala Asp 195 200 205 gtg tac cgc tac ggc att gct gcc ggt gaa cct cgt cgc atc aaa gag 673 Val Tyr Arg Tyr Gly Ile Ala Ala Gly Glu Pro Arg Arg Ile Lys Glu 210 215 220 atc att gaa tcc cag atg ctg cgc tcg gaa atc atc gtc atc acc gga 721 Ile Ile Glu Ser Gln Met Leu Arg Ser Glu Ile Ile Val Ile Thr Gly 225 230 235 240 gct gtt ggc ggt gct ggt tca gct ggc gtg cgc cag gtt ctc aac gag 769 Ala Val Gly Gly Ala Gly Ser Ala Gly Val Arg Gln Val Leu Asn Glu 245 250 255 cta ggc gat atc gac acc gaa cgc gtc gca atg cac ccc ggt tct gtc 817 Leu Gly Asp Ile Asp Thr Glu Arg Val Ala Met His Pro Gly Ser Val 260 265 270 caa gga ttc ggt ctg ctc ggc gag aac aag att cca tgc ttc ctt ctg 865 Gln Gly Phe Gly Leu Leu Gly Glu Asn Lys Ile Pro Cys Phe Leu Leu 275 280 285 cct tcc aat ccg gtg gcg tcg tta gtt att ttt gaa acc ttc gtc cgc 913 Pro Ser Asn Pro Val Ala Ser Leu Val Ile Phe Glu Thr Phe Val Arg 290 295 300 ccg gtc gtg cgc atg agc ctg ggc aag agc aat gcg gcg cgc cgg gtt 961 Pro Val Val Arg Met Ser Leu Gly Lys Ser Asn Ala Ala Arg Arg Val 305 310 315 320 gtt cga gct cga gcg ctc aac cac gtt gtg tct gtg gcg ggt cga aaa 1009 Val Arg Ala Arg Ala Leu Asn His Val Val Ser Val Ala Gly Arg Lys 325 330 335 ggt ttc atc agg tcc agg ctc atg cgc gat gca gaa acc cag gac tac 1057 Gly Phe Ile Arg Ser Arg Leu Met Arg Asp Ala Glu Thr Gln Asp Tyr 340 345 350 ctc gtg gag gct ttg ggt ggt gca acg ggc gca cca tcg cac cta ttg 1105 Leu Val Glu Ala Leu Gly Gly Ala Thr Gly Ala Pro Ser His Leu Leu 355 360 365 gca gga ttg tcc gaa gca aac ggt atg atc cgc att cca gaa gat gtc 1153 Ala Gly Leu Ser Glu Ala Asn Gly Met Ile Arg Ile Pro Glu Asp Val 370 375 380 aca gaa atc cga ccg gga gat gtc gtg gac gtg atc ttc ctt gcc caa 1201 Thr Glu Ile Arg Pro Gly Asp Val Val Asp Val Ile Phe Leu Ala Gln 385 390 395 400 ggt cga tagttcgatg cgtaatgcac cgtcaggtcc 1237 Gly Arg <210> 778 <211> 402 <212> PRT <213> Corynebacterium glutamicum <400> 778 Pro Glu Pro Val Arg Ile Ala Ile Ala Glu Ala Leu Gly Leu Met Cys 1 5 10 15 Ala Glu Glu Val Gln Ala Ser Arg Ala Leu Pro Gly Phe Ala Gln Ala 20 25 30 Ala Ile Asp Gly Tyr Ala Val Arg Ala Val Asp Val Gly Gly Glu Lys 35 40 45 Ser Phe Ser Gln Gln Leu Pro Val Ala Pro Pro Glu Lys Ser Leu Pro 50 55 60 Val Val Gly Glu Val Ala Ala Gly Ser Gln Gln Pro Leu Arg Leu Gln 65 70 75 80 Pro Lys Gln Ala Val Met Val His Thr Gly Ala Pro Leu Pro Met Leu 85 90 95 Ala Asp Ala Val Leu Pro Met Ala Trp Ser Asp Arg Gly Arg Lys Arg 100 105 110 Val Thr Ala Gln Arg Pro Val Arg Ser Gly Glu Phe Val Arg Lys Glu 115 120 125 Gly Asp Asp Ile Gln Pro Gly Asp Ile Ala Val Ser Ala Gly Ala Val 130 135 140 Leu Gly Pro Ala Gln Ile Gly Leu Leu Ala Ala Val Gly Arg Ser Lys 145 150 155 160 Val Leu Val Tyr Pro Arg Pro Arg Met Ser Val Ile Ser Val Gly Ala 165 170 175 Glu Leu Val Asp Ile Asp Arg Gln Pro Gly Leu Gly Gln Val Tyr Asp 180 185 190 Val Asn Ser Tyr Ser Leu Ala Ala Ala Gly Arg Glu Ala Gly Ala Asp 195 200 205 Val Tyr Arg Tyr Gly Ile Ala Ala Gly Glu Pro Arg Arg Ile Lys Glu 210 215 220 Ile Ile Glu Ser Gln Met Leu Arg Ser Glu Ile Ile Val Ile Thr Gly 225 230 235 240 Ala Val Gly Gly Ala Gly Ser Ala Gly Val Arg Gln Val Leu Asn Glu 245 250 255 Leu Gly Asp Ile Asp Thr Glu Arg Val Ala Met His Pro Gly Ser Val 260 265 270 Gln Gly Phe Gly Leu Leu Gly Glu Asn Lys Ile Pro Cys Phe Leu Leu 275 280 285 Pro Ser Asn Pro Val Ala Ser Leu Val Ile Phe Glu Thr Phe Val Arg 290 295 300 Pro Val Val Arg Met Ser Leu Gly Lys Ser Asn Ala Ala Arg Arg Val 305 310 315 320 Val Arg Ala Arg Ala Leu Asn His Val Val Ser Val Ala Gly Arg Lys 325 330 335 Gly Phe Ile Arg Ser Arg Leu Met Arg Asp Ala Glu Thr Gln Asp Tyr 340 345 350 Leu Val Glu Ala Leu Gly Gly Ala Thr Gly Ala Pro Ser His Leu Leu 355 360 365 Ala Gly Leu Ser Glu Ala Asn Gly Met Ile Arg Ile Pro Glu Asp Val 370 375 380 Thr Glu Ile Arg Pro Gly Asp Val Val Asp Val Ile Phe Leu Ala Gln 385 390 395 400 Gly Arg <210> 779 <211> 1229 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1206) <223> FRXA01970 <400> 779 cca gag cca gtg cgt att gct att gca gag gca ctg ggt ttg atg tgc 48 Pro Glu Pro Val Arg Ile Ala Ile Ala Glu Ala Leu Gly Leu Met Cys 1 5 10 15 gcg gaa gag gtt caa gct agt cgt gct ttg ccg ggt ttc gcg caa gca 96 Ala Glu Glu Val Gln Ala Ser Arg Ala Leu Pro Gly Phe Ala Gln Ala 20 25 30 gcg att gat ggt tat gcg gtt cga gca gtc gat gtc ggc ggc gag aag 144 Ala Ile Asp Gly Tyr Ala Val Arg Ala Val Asp Val Gly Gly Glu Lys 35 40 45 tcg ttt agc cag caa ctg ccg gtt gct cct ccg gaa aaa tcc ctg ccc 192 Ser Phe Ser Gln Gln Leu Pro Val Ala Pro Pro Glu Lys Ser Leu Pro 50 55 60 gtg gtg ggt gaa gta gct gcg ggt tct cag cag ccg ttg cgc ctg cag 240 Val Val Gly Glu Val Ala Ala Gly Ser Gln Gln Pro Leu Arg Leu Gln 65 70 75 80 cct aaa caa gca gtc atg gtc cac acc ggt gcg cca ctg ccg atg ctt 288 Pro Lys Gln Ala Val Met Val His Thr Gly Ala Pro Leu Pro Met Leu 85 90 95 gcg gat gcg gtg ctg ccc atg gcg tgg tca gat cgt ggc cgc aaa cga 336 Ala Asp Ala Val Leu Pro Met Ala Trp Ser Asp Arg Gly Arg Lys Arg 100 105 110 gta acc gcg cag cga cct gtg cgc tct ggc gag ttt gtg cgc aaa gaa 384 Val Thr Ala Gln Arg Pro Val Arg Ser Gly Glu Phe Val Arg Lys Glu 115 120 125 ggc gat gac atc caa ccg gga gac atc gca gtc agc gcc ggc gcg gtc 432 Gly Asp Asp Ile Gln Pro Gly Asp Ile Ala Val Ser Ala Gly Ala Val 130 135 140 tta ggc cct gcc caa att ggt ttg ctc gca gct gtt ggt cgc tcc aaa 480 Leu Gly Pro Ala Gln Ile Gly Leu Leu Ala Ala Val Gly Arg Ser Lys 145 150 155 160 gtg ttg gtg tac cca cgc cca cgc atg tcg gtt atc tcc gta ggc gct 528 Val Leu Val Tyr Pro Arg Pro Arg Met Ser Val Ile Ser Val Gly Ala 165 170 175 gaa ctt gtt gat att gat cgc cag cca ggc ctc ggc cag gtt tat gat 576 Glu Leu Val Asp Ile Asp Arg Gln Pro Gly Leu Gly Gln Val Tyr Asp 180 185 190 gtc aat tcc tat tct ctg gct gcc gcc ggt agg gaa gcg ggc gca gat 624 Val Asn Ser Tyr Ser Leu Ala Ala Ala Gly Arg Glu Ala Gly Ala Asp 195 200 205 gtg tac cgc tac ggc att gct gcc ggt gaa cct cgt cgc atc aaa gag 672 Val Tyr Arg Tyr Gly Ile Ala Ala Gly Glu Pro Arg Arg Ile Lys Glu 210 215 220 atc att gaa tcc cag atg ctg cgc tcg gaa atc atc gtc atc acc gga 720 Ile Ile Glu Ser Gln Met Leu Arg Ser Glu Ile Ile Val Ile Thr Gly 225 230 235 240 gct gtt ggc ggt gct ggt tca gct ggc gtg cgc cag gtt ctc aac gag 768 Ala Val Gly Gly Ala Gly Ser Ala Gly Val Arg Gln Val Leu Asn Glu 245 250 255 cta ggc gat atc gac acc gaa cgc gtc gca atg cac ccc ggt tct gtc 816 Leu Gly Asp Ile Asp Thr Glu Arg Val Ala Met His Pro Gly Ser Val 260 265 270 caa gga ttc ggt ctg ctc ggc gag aac aag att cca tgc ttc ctt ctg 864 Gln Gly Phe Gly Leu Leu Gly Glu Asn Lys Ile Pro Cys Phe Leu Leu 275 280 285 cct tcc aat ccg gtg gcg tcg tta gtt att ttt gaa acc ttc gtc cgc 912 Pro Ser Asn Pro Val Ala Ser Leu Val Ile Phe Glu Thr Phe Val Arg 290 295 300 ccg gtc gtg cgc atg agc ctg ggc aag agc aat gcg gcg cgc cgg gtt 960 Pro Val Val Arg Met Ser Leu Gly Lys Ser Asn Ala Ala Arg Arg Val 305 310 315 320 gtt cga gct cga gcg ctc aac cac gtt gtg tct gtg gcg ggt cga aaa 1008 Val Arg Ala Arg Ala Leu Asn His Val Val Ser Val Ala Gly Arg Lys 325 330 335 ggt ttc atc agg tcc agg ctc atg cgc gat gca gaa acc cag gac tac 1056 Gly Phe Ile Arg Ser Arg Leu Met Arg Asp Ala Glu Thr Gln Asp Tyr 340 345 350 ctc gtg gag gct ttg ggt ggt gca acg ggc gca cca tcg cac cta ttg 1104 Leu Val Glu Ala Leu Gly Gly Ala Thr Gly Ala Pro Ser His Leu Leu 355 360 365 gca gga ttg tcc gaa gca aac ggt atg atc cgc att cca gaa gat gtc 1152 Ala Gly Leu Ser Glu Ala Asn Gly Met Ile Arg Ile Pro Glu Asp Val 370 375 380 aca gaa atc cga ccg gga gat gtc gtg gac gtg atc ttc ctt gcc caa 1200 Thr Glu Ile Arg Pro Gly Asp Val Val Asp Val Ile Phe Leu Ala Gln 385 390 395 400 ggt cga tagttcgatg cgtaatgcac cgt 1229 Gly Arg <210> 780 <211> 402 <212> PRT <213> Corynebacterium glutamicum <400> 780 Pro Glu Pro Val Arg Ile Ala Ile Ala Glu Ala Leu Gly Leu Met Cys 1 5 10 15 Ala Glu Glu Val Gln Ala Ser Arg Ala Leu Pro Gly Phe Ala Gln Ala 20 25 30 Ala Ile Asp Gly Tyr Ala Val Arg Ala Val Asp Val Gly Gly Glu Lys 35 40 45 Ser Phe Ser Gln Gln Leu Pro Val Ala Pro Pro Glu Lys Ser Leu Pro 50 55 60 Val Val Gly Glu Val Ala Ala Gly Ser Gln Gln Pro Leu Arg Leu Gln 65 70 75 80 Pro Lys Gln Ala Val Met Val His Thr Gly Ala Pro Leu Pro Met Leu 85 90 95 Ala Asp Ala Val Leu Pro Met Ala Trp Ser Asp Arg Gly Arg Lys Arg 100 105 110 Val Thr Ala Gln Arg Pro Val Arg Ser Gly Glu Phe Val Arg Lys Glu 115 120 125 Gly Asp Asp Ile Gln Pro Gly Asp Ile Ala Val Ser Ala Gly Ala Val 130 135 140 Leu Gly Pro Ala Gln Ile Gly Leu Leu Ala Ala Val Gly Arg Ser Lys 145 150 155 160 Val Leu Val Tyr Pro Arg Pro Arg Met Ser Val Ile Ser Val Gly Ala 165 170 175 Glu Leu Val Asp Ile Asp Arg Gln Pro Gly Leu Gly Gln Val Tyr Asp 180 185 190 Val Asn Ser Tyr Ser Leu Ala Ala Ala Gly Arg Glu Ala Gly Ala Asp 195 200 205 Val Tyr Arg Tyr Gly Ile Ala Ala Gly Glu Pro Arg Arg Ile Lys Glu 210 215 220 Ile Ile Glu Ser Gln Met Leu Arg Ser Glu Ile Ile Val Ile Thr Gly 225 230 235 240 Ala Val Gly Gly Ala Gly Ser Ala Gly Val Arg Gln Val Leu Asn Glu 245 250 255 Leu Gly Asp Ile Asp Thr Glu Arg Val Ala Met His Pro Gly Ser Val 260 265 270 Gln Gly Phe Gly Leu Leu Gly Glu Asn Lys Ile Pro Cys Phe Leu Leu 275 280 285 Pro Ser Asn Pro Val Ala Ser Leu Val Ile Phe Glu Thr Phe Val Arg 290 295 300 Pro Val Val Arg Met Ser Leu Gly Lys Ser Asn Ala Ala Arg Arg Val 305 310 315 320 Val Arg Ala Arg Ala Leu Asn His Val Val Ser Val Ala Gly Arg Lys 325 330 335 Gly Phe Ile Arg Ser Arg Leu Met Arg Asp Ala Glu Thr Gln Asp Tyr 340 345 350 Leu Val Glu Ala Leu Gly Gly Ala Thr Gly Ala Pro Ser His Leu Leu 355 360 365 Ala Gly Leu Ser Glu Ala Asn Gly Met Ile Arg Ile Pro Glu Asp Val 370 375 380 Thr Glu Ile Arg Pro Gly Asp Val Val Asp Val Ile Phe Leu Ala Gln 385 390 395 400 Gly Arg <210> 781 <211> 708 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(685) <223> RXA02629 <400> 781 tacctcgcag agccgggagg tagaggttac tctgacgagt gagtaggttt aaaagagtta 60 atctgcatct aatcaagtag ccaagtatga gtgaggaaca atg agc aag gat cca 115 Met Ser Lys Asp Pro 1 5 ttg gga agt ctt acc gat gtt gta gac aca cga gtt ccg ctt ccg gat 163 Leu Gly Ser Leu Thr Asp Val Val Asp Thr Arg Val Pro Leu Pro Asp 10 15 20 gtt gaa ccg gat ccg gag ttc ctg aag gct acg gaa aaa gaa ttc cac 211 Val Glu Pro Asp Pro Glu Phe Leu Lys Ala Thr Glu Lys Glu Phe His 25 30 35 atg gca tcc cag aag cgc gct ctt gtt gtc ctg gtg ggc gat cat gtc 259 Met Ala Ser Gln Lys Arg Ala Leu Val Val Leu Val Gly Asp His Val 40 45 50 gct gag gca gat ggg act ggc cgt ttg gtt acg gag ctg ctc tta gag 307 Ala Glu Ala Asp Gly Thr Gly Arg Leu Val Thr Glu Leu Leu Leu Glu 55 60 65 tct ggc ttc aac gtg gac gct gtg gtc agc gtg aag tct aag aag tct 355 Ser Gly Phe Asn Val Asp Ala Val Val Ser Val Lys Ser Lys Lys Ser 70 75 80 85 cag att agg caa gct att gaa acc gca gtt gtt ggc ggc gct gac ctt 403 Gln Ile Arg Gln Ala Ile Glu Thr Ala Val Val Gly Gly Ala Asp Leu 90 95 100 gtg ctg acc atc ggc gga gtg ggc gtt ggt cct cgg gat aaa act cct 451 Val Leu Thr Ile Gly Gly Val Gly Val Gly Pro Arg Asp Lys Thr Pro 105 110 115 gag gca acc agc gct gtg ttg gac cag gac gtc cca gga atc gcg cag 499 Glu Ala Thr Ser Ala Val Leu Asp Gln Asp Val Pro Gly Ile Ala Gln 120 125 130 gcg ctt cgt tcc tcc ggt ttg gcc tgt ggc gcg gtg gat gca agt gtt 547 Ala Leu Arg Ser Ser Gly Leu Ala Cys Gly Ala Val Asp Ala Ser Val 135 140 145 tcc cga ggc gta gcg ggc gta tcc ggc tca acc gtg gtg gtc aac ctc 595 Ser Arg Gly Val Ala Gly Val Ser Gly Ser Thr Val Val Val Asn Leu 150 155 160 165 gct gag tct cgt tcg gca att cgt gat ggc atg gca act ctg aca ccg 643 Ala Glu Ser Arg Ser Ala Ile Arg Asp Gly Met Ala Thr Leu Thr Pro 170 175 180 ttg gtt gat ttt gtt gta gat cag ctt cgc act tcc gtg gtt 685 Leu Val Asp Phe Val Val Asp Gln Leu Arg Thr Ser Val Val 185 190 195 tgagttggtc gggtgtgagt aga 708 <210> 782 <211> 195 <212> PRT <213> Corynebacterium glutamicum <400> 782 Met Ser Lys Asp Pro Leu Gly Ser Leu Thr Asp Val Val Asp Thr Arg 1 5 10 15 Val Pro Leu Pro Asp Val Glu Pro Asp Pro Glu Phe Leu Lys Ala Thr 20 25 30 Glu Lys Glu Phe His Met Ala Ser Gln Lys Arg Ala Leu Val Val Leu 35 40 45 Val Gly Asp His Val Ala Glu Ala Asp Gly Thr Gly Arg Leu Val Thr 50 55 60 Glu Leu Leu Leu Glu Ser Gly Phe Asn Val Asp Ala Val Val Ser Val 65 70 75 80 Lys Ser Lys Lys Ser Gln Ile Arg Gln Ala Ile Glu Thr Ala Val Val 85 90 95 Gly Gly Ala Asp Leu Val Leu Thr Ile Gly Gly Val Gly Val Gly Pro 100 105 110 Arg Asp Lys Thr Pro Glu Ala Thr Ser Ala Val Leu Asp Gln Asp Val 115 120 125 Pro Gly Ile Ala Gln Ala Leu Arg Ser Ser Gly Leu Ala Cys Gly Ala 130 135 140 Val Asp Ala Ser Val Ser Arg Gly Val Ala Gly Val Ser Gly Ser Thr 145 150 155 160 Val Val Val Asn Leu Ala Glu Ser Arg Ser Ala Ile Arg Asp Gly Met 165 170 175 Ala Thr Leu Thr Pro Leu Val Asp Phe Val Val Asp Gln Leu Arg Thr 180 185 190 Ser Val Val 195 <210> 783 <211> 402 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(379) <223> RXA02318 <400> 783 gatatacgcc acggtaccgc gtacaaaatc ccgaatatga tcatggccaa aggaggtcag 60 cagtaagcgc atgtgcgcca ttttaaggca agatggggcc atg aat tcg ctt ttc 115 Met Asn Ser Leu Phe 1 5 gac gtc tcc cca cac tgg tcc tcc gcc aac gcc aag ctc acc gca cat 163 Asp Val Ser Pro His Trp Ser Ser Ala Asn Ala Lys Leu Thr Ala His 10 15 20 ttt aac acc gga aaa ttc tcc act ggc atg aaa ttt gtc aac ctc att 211 Phe Asn Thr Gly Lys Phe Ser Thr Gly Met Lys Phe Val Asn Leu Ile 25 30 35 gcc gac tcc gca gaa gaa gcc aac cac cac ccc gat atc ctt ctc acc 259 Ala Asp Ser Ala Glu Glu Ala Asn His His Pro Asp Ile Leu Leu Thr 40 45 50 tat ggt ttt gtg gaa atc acc ctc acc agc cac gat gtg ggt gag ata 307 Tyr Gly Phe Val Glu Ile Thr Leu Thr Ser His Asp Val Gly Glu Ile 55 60 65 acc gac cgt gat gtc gcc cta gca aaa gtc atc gac gcc cac gcc aag 355 Thr Asp Arg Asp Val Ala Leu Ala Lys Val Ile Asp Ala His Ala Lys 70 75 80 85 acc ttg gcc att tcg gca gag gct taaggttaaa gattatgagc aac 402 Thr Leu Ala Ile Ser Ala Glu Ala 90 <210> 784 <211> 93 <212> PRT <213> Corynebacterium glutamicum <400> 784 Met Asn Ser Leu Phe Asp Val Ser Pro His Trp Ser Ser Ala Asn Ala 1 5 10 15 Lys Leu Thr Ala His Phe Asn Thr Gly Lys Phe Ser Thr Gly Met Lys 20 25 30 Phe Val Asn Leu Ile Ala Asp Ser Ala Glu Glu Ala Asn His His Pro 35 40 45 Asp Ile Leu Leu Thr Tyr Gly Phe Val Glu Ile Thr Leu Thr Ser His 50 55 60 Asp Val Gly Glu Ile Thr Asp Arg Asp Val Ala Leu Ala Lys Val Ile 65 70 75 80 Asp Ala His Ala Lys Thr Leu Ala Ile Ser Ala Glu Ala 85 90 <210> 785 <211> 600 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(577) <223> RXA01517 <400> 785 tccataagcc caaagcaccg atcccacgta cttttgctga cgtcgcggtg gttgcccgac 60 gttccaggaa atccatggct gctggaagga gcaacgccta atg cat gca gtt ttg 115 Met His Ala Val Leu 1 5 tcc atc ggt tcc aac atg gat gat cgc tac gcg ctg ctc aac aca gtg 163 Ser Ile Gly Ser Asn Met Asp Asp Arg Tyr Ala Leu Leu Asn Thr Val 10 15 20 atc gag gaa ttc aaa gat gag atc gtg gcg cag tct gcg atc tac tca 211 Ile Glu Glu Phe Lys Asp Glu Ile Val Ala Gln Ser Ala Ile Tyr Ser 25 30 35 acc cca ccg tgg ggc att gag gat cag gat gaa ttc ctc aac gca gtg 259 Thr Pro Pro Trp Gly Ile Glu Asp Gln Asp Glu Phe Leu Asn Ala Val 40 45 50 ctc gtt gtt gag gtt gaa gaa acc ccc atc gag ttg ctg cgc cgt ggc 307 Leu Val Val Glu Val Glu Glu Thr Pro Ile Glu Leu Leu Arg Arg Gly 55 60 65 caa aaa ctc gaa gaa gcc gcc gag cgg gtc cgc gtc cgc aaa tgg ggg 355 Gln Lys Leu Glu Glu Ala Ala Glu Arg Val Arg Val Arg Lys Trp Gly 70 75 80 85 cca cgc acc ctc gat gtg gat atc gtg cag atc att aaa gat ggg gaa 403 Pro Arg Thr Leu Asp Val Asp Ile Val Gln Ile Ile Lys Asp Gly Glu 90 95 100 gag atc ctt tct gag gat ccc gaa ctg acc ttg cca cac cct tgg gct 451 Glu Ile Leu Ser Glu Asp Pro Glu Leu Thr Leu Pro His Pro Trp Ala 105 110 115 tgg cag cgt gcc ttc gtg ttg atc cct tgg ttg gaa gca gaa cct gat 499 Trp Gln Arg Ala Phe Val Leu Ile Pro Trp Leu Glu Ala Glu Pro Asp 120 125 130 gcc gtc ctg cac ggc acg acc att gca gaa cat gtg gat aat ctt gat 547 Ala Val Leu His Gly Thr Thr Ile Ala Glu His Val Asp Asn Leu Asp 135 140 145 ccc aca gac att gaa ggt gtc acc aag att taaggagtcg tggctttcat 597 Pro Thr Asp Ile Glu Gly Val Thr Lys Ile 150 155 gca 600 <210> 786 <211> 159 <212> PRT <213> Corynebacterium glutamicum <400> 786 Met His Ala Val Leu Ser Ile Gly Ser Asn Met Asp Asp Arg Tyr Ala 1 5 10 15 Leu Leu Asn Thr Val Ile Glu Glu Phe Lys Asp Glu Ile Val Ala Gln 20 25 30 Ser Ala Ile Tyr Ser Thr Pro Pro Trp Gly Ile Glu Asp Gln Asp Glu 35 40 45 Phe Leu Asn Ala Val Leu Val Val Glu Val Glu Glu Thr Pro Ile Glu 50 55 60 Leu Leu Arg Arg Gly Gln Lys Leu Glu Glu Ala Ala Glu Arg Val Arg 65 70 75 80 Val Arg Lys Trp Gly Pro Arg Thr Leu Asp Val Asp Ile Val Gln Ile 85 90 95 Ile Lys Asp Gly Glu Glu Ile Leu Ser Glu Asp Pro Glu Leu Thr Leu 100 105 110 Pro His Pro Trp Ala Trp Gln Arg Ala Phe Val Leu Ile Pro Trp Leu 115 120 125 Glu Ala Glu Pro Asp Ala Val Leu His Gly Thr Thr Ile Ala Glu His 130 135 140 Val Asp Asn Leu Asp Pro Thr Asp Ile Glu Gly Val Thr Lys Ile 145 150 155 <210> 787 <211> 609 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(586) <223> RXN01304 <400> 787 atgcaggtaa acgaatttgt gcttatatca acattcgtga ttcggcaaaa ttaattaaac 60 tgaaaaaggg gattaattac ccccacttga ggagaaattg atg ccc gca cag aac 115 Met Pro Ala Gln Asn 1 5 aaa aac ctc cca gga tcc gtc atc gtt gtg tct gat cgg att aaa tcg 163 Lys Asn Leu Pro Gly Ser Val Ile Val Val Ser Asp Arg Ile Lys Ser 10 15 20 gga gaa aga att gat aaa gca gga ccc gta gca gta gac ctt ctt cag 211 Gly Glu Arg Ile Asp Lys Ala Gly Pro Val Ala Val Asp Leu Leu Gln 25 30 35 gaa tca ggc gtg gag att tcc aca ttc acc gtc gtg gag gag ggc ttt 259 Glu Ser Gly Val Glu Ile Ser Thr Phe Thr Val Val Glu Glu Gly Phe 40 45 50 gaa cct gtc cat caa gaa ttg gtt aag gcg ttg gcg cgc cgg gat cgc 307 Glu Pro Val His Gln Glu Leu Val Lys Ala Leu Ala Arg Arg Asp Arg 55 60 65 gtc atc atc acc atc ggc gga acg ggc gtg ggg cct aga aat cgg acg 355 Val Ile Ile Thr Ile Gly Gly Thr Gly Val Gly Pro Arg Asn Arg Thr 70 75 80 85 ccg gag gcc aca gaa ccg cac atc gat acg cta ctg ccg ggt ctg atg 403 Pro Glu Ala Thr Glu Pro His Ile Asp Thr Leu Leu Pro Gly Leu Met 90 95 100 acg cag att ttg ttc tct gga ctg tcc aat acc gcg cag gcg ggg tta 451 Thr Gln Ile Leu Phe Ser Gly Leu Ser Asn Thr Ala Gln Ala Gly Leu 105 110 115 tct cgg ggg ctg gtg ggc ttg agt gct cgc gat tcc acg gcc gcg ctc 499 Ser Arg Gly Leu Val Gly Leu Ser Ala Arg Asp Ser Thr Ala Ala Leu 120 125 130 atc gtc aac gcg ccg agt tct tcc ggg ggc gtg cgc gac gcg ctc ggg 547 Ile Val Asn Ala Pro Ser Ser Ser Gly Gly Val Arg Asp Ala Leu Gly 135 140 145 gtg gtc tgc ccg ctt ttc ggt tcc att ttt gag cgt ctt taaaagattt 596 Val Val Cys Pro Leu Phe Gly Ser Ile Phe Glu Arg Leu 150 155 160 ttgcttatcg acg 609 <210> 788 <211> 162 <212> PRT <213> Corynebacterium glutamicum <400> 788 Met Pro Ala Gln Asn Lys Asn Leu Pro Gly Ser Val Ile Val Val Ser 1 5 10 15 Asp Arg Ile Lys Ser Gly Glu Arg Ile Asp Lys Ala Gly Pro Val Ala 20 25 30 Val Asp Leu Leu Gln Glu Ser Gly Val Glu Ile Ser Thr Phe Thr Val 35 40 45 Val Glu Glu Gly Phe Glu Pro Val His Gln Glu Leu Val Lys Ala Leu 50 55 60 Ala Arg Arg Asp Arg Val Ile Ile Thr Ile Gly Gly Thr Gly Val Gly 65 70 75 80 Pro Arg Asn Arg Thr Pro Glu Ala Thr Glu Pro His Ile Asp Thr Leu 85 90 95 Leu Pro Gly Leu Met Thr Gln Ile Leu Phe Ser Gly Leu Ser Asn Thr 100 105 110 Ala Gln Ala Gly Leu Ser Arg Gly Leu Val Gly Leu Ser Ala Arg Asp 115 120 125 Ser Thr Ala Ala Leu Ile Val Asn Ala Pro Ser Ser Ser Gly Gly Val 130 135 140 Arg Asp Ala Leu Gly Val Val Cys Pro Leu Phe Gly Ser Ile Phe Glu 145 150 155 160 Arg Leu <210> 789 <211> 1281 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1258) <223> RXS02556 <400> 789 tgccatcata ttaaggccaa attgcttgga tcctgggatt tatttaatta gattaaatcc 60 gtagaaatta gcccatgaag catggaaagg cgaaaacccc ttg atc gtt tcc acc 115 Leu Ile Val Ser Thr 1 5 cag ccc att act gat cgc agc gca ctc tcg gca gaa cac gca gag gtg 163 Gln Pro Ile Thr Asp Arg Ser Ala Leu Ser Ala Glu His Ala Glu Val 10 15 20 atc aaa gca acg ctt cct ctc gtg ggc ggc aag att aat gag atc acg 211 Ile Lys Ala Thr Leu Pro Leu Val Gly Gly Lys Ile Asn Glu Ile Thr 25 30 35 ccg gtt ttc tac aac aag atg ttt gcg gct cac cca gaa ttg atc gct 259 Pro Val Phe Tyr Asn Lys Met Phe Ala Ala His Pro Glu Leu Ile Ala 40 45 50 aac acc ttc aac cgt ggc aat cag aag caa ggc gat cag cag aag gcg 307 Asn Thr Phe Asn Arg Gly Asn Gln Lys Gln Gly Asp Gln Gln Lys Ala 55 60 65 ctg gcg gct tcg att gca acg ttt gcc acc atg ctc gtt act cct gat 355 Leu Ala Ala Ser Ile Ala Thr Phe Ala Thr Met Leu Val Thr Pro Asp 70 75 80 85 gct cct gac cca gtt cag ctg ctg tcc cgc att ggc cac aag cac gtg 403 Ala Pro Asp Pro Val Gln Leu Leu Ser Arg Ile Gly His Lys His Val 90 95 100 tcc ctc ggc att act gct gat cag tac gac att gtt cac gag cac ctg 451 Ser Leu Gly Ile Thr Ala Asp Gln Tyr Asp Ile Val His Glu His Leu 105 110 115 ttc gcc gca atc gtt gag gtt ttg gga gcg gaa act gtc acc gca cct 499 Phe Ala Ala Ile Val Glu Val Leu Gly Ala Glu Thr Val Thr Ala Pro 120 125 130 gtc gct gaa gcc tgg gat gct gtc tac tgg atc atg gca aat gtg ctg 547 Val Ala Glu Ala Trp Asp Ala Val Tyr Trp Ile Met Ala Asn Val Leu 135 140 145 atc ggt ttt gag aac aac ctt tat gct tcc aac gat ctg gag cct ggc 595 Ile Gly Phe Glu Asn Asn Leu Tyr Ala Ser Asn Asp Leu Glu Pro Gly 150 155 160 165 gac gtc ttc cgc gaa gtc acc gtg acc gcg aag aag cag ctc agc gca 643 Asp Val Phe Arg Glu Val Thr Val Thr Ala Lys Lys Gln Leu Ser Ala 170 175 180 acc gtc tgg gaa tac acc ctg gca ggt gag ctg gtt gcc cca gag cca 691 Thr Val Trp Glu Tyr Thr Leu Ala Gly Glu Leu Val Ala Pro Glu Pro 185 190 195 ggt cag tac acc tcc atc gga gta gtg ctt gac gac ggc gcc cgc cag 739 Gly Gln Tyr Thr Ser Ile Gly Val Val Leu Asp Asp Gly Ala Arg Gln 200 205 210 ctg cgc cag tac agc ttg ctc ggc ggc tcc gac acc gag tac cgc att 787 Leu Arg Gln Tyr Ser Leu Leu Gly Gly Ser Asp Thr Glu Tyr Arg Ile 215 220 225 gcg gtt gag gat aac ggc gag gtt tct gga ttc ctg cgt gat cgc gta 835 Ala Val Glu Asp Asn Gly Glu Val Ser Gly Phe Leu Arg Asp Arg Val 230 235 240 245 tcc gtt ggt gac aag att gaa gcc acc atc gcg gcc ggc gac ctg gtt 883 Ser Val Gly Asp Lys Ile Glu Ala Thr Ile Ala Ala Gly Asp Leu Val 250 255 260 ctt aac aag gac acc aat cca gtt gtg ctg att tcc cag ggc atc ggc 931 Leu Asn Lys Asp Thr Asn Pro Val Val Leu Ile Ser Gln Gly Ile Gly 265 270 275 tcc acc cca atg gtg ggc atg ctc gca ggt atg aac cct gaa cgt gac 979 Ser Thr Pro Met Val Gly Met Leu Ala Gly Met Asn Pro Glu Arg Asp 280 285 290 gtt gtg gtt ttg cat gct gac cag gcc gag tcc acc tac gcg cag gtg 1027 Val Val Val Leu His Ala Asp Gln Ala Glu Ser Thr Tyr Ala Gln Val 295 300 305 gag gaa gtg cag ggg ctc gtc gaa aag ctc cct aag gct gcg ttt gaa 1075 Glu Glu Val Gln Gly Leu Val Glu Lys Leu Pro Lys Ala Ala Phe Glu 310 315 320 325 atc ttc tac cgc gac aac gac cag tgg ctc gag gtc gct ggc cgc att 1123 Ile Phe Tyr Arg Asp Asn Asp Gln Trp Leu Glu Val Ala Gly Arg Ile 330 335 340 cca tca ggt gcg tcc gtg tac ctg tgc ggt ggc gtg gaa ttc ttg aag 1171 Pro Ser Gly Ala Ser Val Tyr Leu Cys Gly Gly Val Glu Phe Leu Lys 345 350 355 aac gtg cgt gag cag atc gag gcg ctc gat gag cag cct cgc gac gta 1219 Asn Val Arg Glu Gln Ile Glu Ala Leu Asp Glu Gln Pro Arg Asp Val 360 365 370 aac ttc gag ctc ttc gca cca aac gac tgg ctg att tcc taagcccaca 1268 Asn Phe Glu Leu Phe Ala Pro Asn Asp Trp Leu Ile Ser 375 380 385 ccccagaact tcc 1281 <210> 790 <211> 386 <212> PRT <213> Corynebacterium glutamicum <400> 790 Leu Ile Val Ser Thr Gln Pro Ile Thr Asp Arg Ser Ala Leu Ser Ala 1 5 10 15 Glu His Ala Glu Val Ile Lys Ala Thr Leu Pro Leu Val Gly Gly Lys 20 25 30 Ile Asn Glu Ile Thr Pro Val Phe Tyr Asn Lys Met Phe Ala Ala His 35 40 45 Pro Glu Leu Ile Ala Asn Thr Phe Asn Arg Gly Asn Gln Lys Gln Gly 50 55 60 Asp Gln Gln Lys Ala Leu Ala Ala Ser Ile Ala Thr Phe Ala Thr Met 65 70 75 80 Leu Val Thr Pro Asp Ala Pro Asp Pro Val Gln Leu Leu Ser Arg Ile 85 90 95 Gly His Lys His Val Ser Leu Gly Ile Thr Ala Asp Gln Tyr Asp Ile 100 105 110 Val His Glu His Leu Phe Ala Ala Ile Val Glu Val Leu Gly Ala Glu 115 120 125 Thr Val Thr Ala Pro Val Ala Glu Ala Trp Asp Ala Val Tyr Trp Ile 130 135 140 Met Ala Asn Val Leu Ile Gly Phe Glu Asn Asn Leu Tyr Ala Ser Asn 145 150 155 160 Asp Leu Glu Pro Gly Asp Val Phe Arg Glu Val Thr Val Thr Ala Lys 165 170 175 Lys Gln Leu Ser Ala Thr Val Trp Glu Tyr Thr Leu Ala Gly Glu Leu 180 185 190 Val Ala Pro Glu Pro Gly Gln Tyr Thr Ser Ile Gly Val Val Leu Asp 195 200 205 Asp Gly Ala Arg Gln Leu Arg Gln Tyr Ser Leu Leu Gly Gly Ser Asp 210 215 220 Thr Glu Tyr Arg Ile Ala Val Glu Asp Asn Gly Glu Val Ser Gly Phe 225 230 235 240 Leu Arg Asp Arg Val Ser Val Gly Asp Lys Ile Glu Ala Thr Ile Ala 245 250 255 Ala Gly Asp Leu Val Leu Asn Lys Asp Thr Asn Pro Val Val Leu Ile 260 265 270 Ser Gln Gly Ile Gly Ser Thr Pro Met Val Gly Met Leu Ala Gly Met 275 280 285 Asn Pro Glu Arg Asp Val Val Val Leu His Ala Asp Gln Ala Glu Ser 290 295 300 Thr Tyr Ala Gln Val Glu Glu Val Gln Gly Leu Val Glu Lys Leu Pro 305 310 315 320 Lys Ala Ala Phe Glu Ile Phe Tyr Arg Asp Asn Asp Gln Trp Leu Glu 325 330 335 Val Ala Gly Arg Ile Pro Ser Gly Ala Ser Val Tyr Leu Cys Gly Gly 340 345 350 Val Glu Phe Leu Lys Asn Val Arg Glu Gln Ile Glu Ala Leu Asp Glu 355 360 365 Gln Pro Arg Asp Val Asn Phe Glu Leu Phe Ala Pro Asn Asp Trp Leu 370 375 380 Ile Ser 385 <210> 791 <211> 990 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(967) <223> RXS02560 <400> 791 ttggggcaag ccagctaacg catttcttgt ggaaaccgca gacattgagg ccgcccacgc 60 ggaacttcta agagcagtgg aatgaaataa tccggtgctg atg cag ggc aac tcg 115 Met Gln Gly Asn Ser 1 5 ctt aat ctg gca gac aac agc gag aga aag aag ccc atg ccg tca cca 163 Leu Asn Leu Ala Asp Asn Ser Glu Arg Lys Lys Pro Met Pro Ser Pro 10 15 20 gga gaa ctt tta gcc gcc cgc tac gga caa cct gca acc tgg acg cca 211 Gly Glu Leu Leu Ala Ala Arg Tyr Gly Gln Pro Ala Thr Trp Thr Pro 25 30 35 ccg cag tgg aat gag acg ctt gat gtc att cac cag cat cga tca gtt 259 Pro Gln Trp Asn Glu Thr Leu Asp Val Ile His Gln His Arg Ser Val 40 45 50 cgc agg tgg ttg gat aaa ccg gtt gat gat gac acc atc cgc acc att 307 Arg Arg Trp Leu Asp Lys Pro Val Asp Asp Asp Thr Ile Arg Thr Ile 55 60 65 att tcc gcc gca caa tcg gct gga acc tct tcc aat aag cag gtc att 355 Ile Ser Ala Ala Gln Ser Ala Gly Thr Ser Ser Asn Lys Gln Val Ile 70 75 80 85 tct gtc atc gtg gtt aaa gat cct gag ctg agg aaa ggc ctc gcg ggg 403 Ser Val Ile Val Val Lys Asp Pro Glu Leu Arg Lys Gly Leu Ala Gly 90 95 100 atc act cgc cag atg ttt ccg cac ctt gag cag gtt ccc gcg gtg ctg 451 Ile Thr Arg Gln Met Phe Pro His Leu Glu Gln Val Pro Ala Val Leu 105 110 115 att tgg ttg att gat tat tcc cga atc agt gcg gtg gca gcc aga gaa 499 Ile Trp Leu Ile Asp Tyr Ser Arg Ile Ser Ala Val Ala Ala Arg Glu 120 125 130 gat ctc cca aca ggg gct ctt gat tat ctc gat gag gcc gcg tgg ggg 547 Asp Leu Pro Thr Gly Ala Leu Asp Tyr Leu Asp Glu Ala Ala Trp Gly 135 140 145 ttc ctc gac gcc gga atc gca gct caa aac gct gca att gct gcg gag 595 Phe Leu Asp Ala Gly Ile Ala Ala Gln Asn Ala Ala Ile Ala Ala Glu 150 155 160 165 tca ctt gga ttg gga acg ctc tat ttg ggt tcg gtg cgc aac gat gcg 643 Ser Leu Gly Leu Gly Thr Leu Tyr Leu Gly Ser Val Arg Asn Asp Ala 170 175 180 gaa gcc gtg cac aaa ttg ctt ggc ctt cca cct gag atc gtg cct gtc 691 Glu Ala Val His Lys Leu Leu Gly Leu Pro Pro Glu Ile Val Pro Val 185 190 195 gtg ggc ttg gaa atg ggg cat gcg gat ccg cct gaa cct gcc gga att 739 Val Gly Leu Glu Met Gly His Ala Asp Pro Pro Glu Pro Ala Gly Ile 200 205 210 aaa cct ccc ctg cca caa gaa gcc att gtt cac tgg gat acc tac acc 787 Lys Pro Pro Leu Pro Gln Glu Ala Ile Val His Trp Asp Thr Tyr Thr 215 220 225 gag aaa aac ctc gaa ctt atc gat tcc tac gac cgc gcc ctc gac act 835 Glu Lys Asn Leu Glu Leu Ile Asp Ser Tyr Asp Arg Ala Leu Asp Thr 230 235 240 245 tac tat tct cgc tac ggc cag cac cag ctc tgg tcg aag cag acg gcg 883 Tyr Tyr Ser Arg Tyr Gly Gln His Gln Leu Trp Ser Lys Gln Thr Ala 250 255 260 cat agg gcg gcg tcg aaa agc ttt tca aaa acc aac agg cag ttc ctt 931 His Arg Ala Ala Ser Lys Ser Phe Ser Lys Thr Asn Arg Gln Phe Leu 265 270 275 agg ggc gtg ttt gag cgc gcc ggg ttt ggg ctg aga taaaagcatg 977 Arg Gly Val Phe Glu Arg Ala Gly Phe Gly Leu Arg 280 285 attatggacg cct 990 <210> 792 <211> 289 <212> PRT <213> Corynebacterium glutamicum <400> 792 Met Gln Gly Asn Ser Leu Asn Leu Ala Asp Asn Ser Glu Arg Lys Lys 1 5 10 15 Pro Met Pro Ser Pro Gly Glu Leu Leu Ala Ala Arg Tyr Gly Gln Pro 20 25 30 Ala Thr Trp Thr Pro Pro Gln Trp Asn Glu Thr Leu Asp Val Ile His 35 40 45 Gln His Arg Ser Val Arg Arg Trp Leu Asp Lys Pro Val Asp Asp Asp 50 55 60 Thr Ile Arg Thr Ile Ile Ser Ala Ala Gln Ser Ala Gly Thr Ser Ser 65 70 75 80 Asn Lys Gln Val Ile Ser Val Ile Val Val Lys Asp Pro Glu Leu Arg 85 90 95 Lys Gly Leu Ala Gly Ile Thr Arg Gln Met Phe Pro His Leu Glu Gln 100 105 110 Val Pro Ala Val Leu Ile Trp Leu Ile Asp Tyr Ser Arg Ile Ser Ala 115 120 125 Val Ala Ala Arg Glu Asp Leu Pro Thr Gly Ala Leu Asp Tyr Leu Asp 130 135 140 Glu Ala Ala Trp Gly Phe Leu Asp Ala Gly Ile Ala Ala Gln Asn Ala 145 150 155 160 Ala Ile Ala Ala Glu Ser Leu Gly Leu Gly Thr Leu Tyr Leu Gly Ser 165 170 175 Val Arg Asn Asp Ala Glu Ala Val His Lys Leu Leu Gly Leu Pro Pro 180 185 190 Glu Ile Val Pro Val Val Gly Leu Glu Met Gly His Ala Asp Pro Pro 195 200 205 Glu Pro Ala Gly Ile Lys Pro Pro Leu Pro Gln Glu Ala Ile Val His 210 215 220 Trp Asp Thr Tyr Thr Glu Lys Asn Leu Glu Leu Ile Asp Ser Tyr Asp 225 230 235 240 Arg Ala Leu Asp Thr Tyr Tyr Ser Arg Tyr Gly Gln His Gln Leu Trp 245 250 255 Ser Lys Gln Thr Ala His Arg Ala Ala Ser Lys Ser Phe Ser Lys Thr 260 265 270 Asn Arg Gln Phe Leu Arg Gly Val Phe Glu Arg Ala Gly Phe Gly Leu 275 280 285 Arg <210> 793 <211> 1425 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1402) <223> RXA00382 <400> 793 aaaacactat tgaccacccc aatcgctgtt gagagtttgt aaagttcgac tgtcaacgag 60 ctggattggc ttcacagatt gaattaatac aatgacgcac atg aca tcg tcc aat 115 Met Thr Ser Ser Asn 1 5 acg gct cga tcc gca gag tgg ttt gaa aag gct cag aag ctc acc cct 163 Thr Ala Arg Ser Ala Glu Trp Phe Glu Lys Ala Gln Lys Leu Thr Pro 10 15 20 ggt ggt gtg aat tct cct gtt cgc gct ttc ggt tca gtt ggc gga caa 211 Gly Gly Val Asn Ser Pro Val Arg Ala Phe Gly Ser Val Gly Gly Gln 25 30 35 gcc cgt ttc atc gaa aaa gct cac ggt tca acg ctg atc gat gtg gac 259 Ala Arg Phe Ile Glu Lys Ala His Gly Ser Thr Leu Ile Asp Val Asp 40 45 50 gga aat gaa tac gtt gac ctg gtc tgt tct tgg ggc ccc atg ctg atg 307 Gly Asn Glu Tyr Val Asp Leu Val Cys Ser Trp Gly Pro Met Leu Met 55 60 65 ggt cac gct cac cca gca gtg gtc gag gct gtg cag aag gcc gtc gtg 355 Gly His Ala His Pro Ala Val Val Glu Ala Val Gln Lys Ala Val Val 70 75 80 85 gat ggt ctt tct ttc ggc gct ccc acc atc ggt gag gtt gag ttg gcc 403 Asp Gly Leu Ser Phe Gly Ala Pro Thr Ile Gly Glu Val Glu Leu Ala 90 95 100 caa gat atc gtc aag cgc act tct gtg gag gaa gtc cgc ctg gtc aac 451 Gln Asp Ile Val Lys Arg Thr Ser Val Glu Glu Val Arg Leu Val Asn 105 110 115 tcc ggc act gag gcc acc atg tcg gcg gtt cgt ctg gcg cgc ggt tac 499 Ser Gly Thr Glu Ala Thr Met Ser Ala Val Arg Leu Ala Arg Gly Tyr 120 125 130 act cag cgt tcc aag att ttg aag ttt gag ggc tgc tac cac ggc cac 547 Thr Gln Arg Ser Lys Ile Leu Lys Phe Glu Gly Cys Tyr His Gly His 135 140 145 gtc gat gcg ctg ctc gca tct gct ggt tct ggt gtc gca act ttc gct 595 Val Asp Ala Leu Leu Ala Ser Ala Gly Ser Gly Val Ala Thr Phe Ala 150 155 160 165 ctg cct gat tcc cca ggc atc acc ggc gct cag act tct gac act att 643 Leu Pro Asp Ser Pro Gly Ile Thr Gly Ala Gln Thr Ser Asp Thr Ile 170 175 180 gtt gtt cct tac aac gac att gaa gcc gtg cgc aac gct ttt gcg gag 691 Val Val Pro Tyr Asn Asp Ile Glu Ala Val Arg Asn Ala Phe Ala Glu 185 190 195 tac cca ggc gag atc gcc tgc atc atc gca gag gca gcc ggt ggc aac 739 Tyr Pro Gly Glu Ile Ala Cys Ile Ile Ala Glu Ala Ala Gly Gly Asn 200 205 210 atg ggc acc gtc gct cca aag gac aac ttt aac gac aag ctt ctc gcg 787 Met Gly Thr Val Ala Pro Lys Asp Asn Phe Asn Asp Lys Leu Leu Ala 215 220 225 atc gct cac gct gac ggc gcg ctg ctg atc ctc gat gaa gtc atg acc 835 Ile Ala His Ala Asp Gly Ala Leu Leu Ile Leu Asp Glu Val Met Thr 230 235 240 245 ggc ttc cgc acc tct tac cgt ggc tgg ttc ggc gta gac aag gtt gcc 883 Gly Phe Arg Thr Ser Tyr Arg Gly Trp Phe Gly Val Asp Lys Val Ala 250 255 260 gct gac ctg gtc acc ttc ggc aag gtc gtc tcc ggc ggc cta cct gcc 931 Ala Asp Leu Val Thr Phe Gly Lys Val Val Ser Gly Gly Leu Pro Ala 265 270 275 gca gcg ttt ggc ggc aag gct gaa atc atg aac atg ctg gcc cca cag 979 Ala Ala Phe Gly Gly Lys Ala Glu Ile Met Asn Met Leu Ala Pro Gln 280 285 290 ggc ccc gtc tac caa gca ggc aca ctg tcc ggc aac ccg gtt gcg gtc 1027 Gly Pro Val Tyr Gln Ala Gly Thr Leu Ser Gly Asn Pro Val Ala Val 295 300 305 gca gct ggt cgg gca tcg ctt aag ctt gcc gac gaa tcc ctc tac aca 1075 Ala Ala Gly Arg Ala Ser Leu Lys Leu Ala Asp Glu Ser Leu Tyr Thr 310 315 320 325 acc atc aac gcc aac gca gat cgt ctc cac ggt ttg atc tct gat gcc 1123 Thr Ile Asn Ala Asn Ala Asp Arg Leu His Gly Leu Ile Ser Asp Ala 330 335 340 tta acc cac gaa ggc gta gcc cac cac att cag cgt gcc tca aac atg 1171 Leu Thr His Glu Gly Val Ala His His Ile Gln Arg Ala Ser Asn Met 345 350 355 ctg tct atc cgt ttt gca gaa ggt gag ggc cac aac ttc tct gat atg 1219 Leu Ser Ile Arg Phe Ala Glu Gly Glu Gly His Asn Phe Ser Asp Met 360 365 370 aag gca gcc gac atc ttc cgc ttc gca ccg ttc ttc cac act ttg ctg 1267 Lys Ala Ala Asp Ile Phe Arg Phe Ala Pro Phe Phe His Thr Leu Leu 375 380 385 gac aac ggc gtc tac gca cca cca agc gtt ttc gaa acc tgg ttt gtg 1315 Asp Asn Gly Val Tyr Ala Pro Pro Ser Val Phe Glu Thr Trp Phe Val 390 395 400 405 tct tcc gct ctc acg gac gat gat ttc tcc aag atc gag cag gca ctc 1363 Ser Ser Ala Leu Thr Asp Asp Asp Phe Ser Lys Ile Glu Gln Ala Leu 410 415 420 aag ccc gcc gca cgt gca gca gca gaa gcg aag gca tca tgacgcaaac 1412 Lys Pro Ala Ala Arg Ala Ala Ala Glu Ala Lys Ala Ser 425 430 cattgtccat cta 1425 <210> 794 <211> 434 <212> PRT <213> Corynebacterium glutamicum <400> 794 Met Thr Ser Ser Asn Thr Ala Arg Ser Ala Glu Trp Phe Glu Lys Ala 1 5 10 15 Gln Lys Leu Thr Pro Gly Gly Val Asn Ser Pro Val Arg Ala Phe Gly 20 25 30 Ser Val Gly Gly Gln Ala Arg Phe Ile Glu Lys Ala His Gly Ser Thr 35 40 45 Leu Ile Asp Val Asp Gly Asn Glu Tyr Val Asp Leu Val Cys Ser Trp 50 55 60 Gly Pro Met Leu Met Gly His Ala His Pro Ala Val Val Glu Ala Val 65 70 75 80 Gln Lys Ala Val Val Asp Gly Leu Ser Phe Gly Ala Pro Thr Ile Gly 85 90 95 Glu Val Glu Leu Ala Gln Asp Ile Val Lys Arg Thr Ser Val Glu Glu 100 105 110 Val Arg Leu Val Asn Ser Gly Thr Glu Ala Thr Met Ser Ala Val Arg 115 120 125 Leu Ala Arg Gly Tyr Thr Gln Arg Ser Lys Ile Leu Lys Phe Glu Gly 130 135 140 Cys Tyr His Gly His Val Asp Ala Leu Leu Ala Ser Ala Gly Ser Gly 145 150 155 160 Val Ala Thr Phe Ala Leu Pro Asp Ser Pro Gly Ile Thr Gly Ala Gln 165 170 175 Thr Ser Asp Thr Ile Val Val Pro Tyr Asn Asp Ile Glu Ala Val Arg 180 185 190 Asn Ala Phe Ala Glu Tyr Pro Gly Glu Ile Ala Cys Ile Ile Ala Glu 195 200 205 Ala Ala Gly Gly Asn Met Gly Thr Val Ala Pro Lys Asp Asn Phe Asn 210 215 220 Asp Lys Leu Leu Ala Ile Ala His Ala Asp Gly Ala Leu Leu Ile Leu 225 230 235 240 Asp Glu Val Met Thr Gly Phe Arg Thr Ser Tyr Arg Gly Trp Phe Gly 245 250 255 Val Asp Lys Val Ala Ala Asp Leu Val Thr Phe Gly Lys Val Val Ser 260 265 270 Gly Gly Leu Pro Ala Ala Ala Phe Gly Gly Lys Ala Glu Ile Met Asn 275 280 285 Met Leu Ala Pro Gln Gly Pro Val Tyr Gln Ala Gly Thr Leu Ser Gly 290 295 300 Asn Pro Val Ala Val Ala Ala Gly Arg Ala Ser Leu Lys Leu Ala Asp 305 310 315 320 Glu Ser Leu Tyr Thr Thr Ile Asn Ala Asn Ala Asp Arg Leu His Gly 325 330 335 Leu Ile Ser Asp Ala Leu Thr His Glu Gly Val Ala His His Ile Gln 340 345 350 Arg Ala Ser Asn Met Leu Ser Ile Arg Phe Ala Glu Gly Glu Gly His 355 360 365 Asn Phe Ser Asp Met Lys Ala Ala Asp Ile Phe Arg Phe Ala Pro Phe 370 375 380 Phe His Thr Leu Leu Asp Asn Gly Val Tyr Ala Pro Pro Ser Val Phe 385 390 395 400 Glu Thr Trp Phe Val Ser Ser Ala Leu Thr Asp Asp Asp Phe Ser Lys 405 410 415 Ile Glu Gln Ala Leu Lys Pro Ala Ala Arg Ala Ala Ala Glu Ala Lys 420 425 430 Ala Ser <210> 795 <211> 1233 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1210) <223> RXA00156 <400> 795 accgagagcg tggtacgcct catttagttt cctcctatga atcttgatgt ggttcatgcg 60 tttttatgca atatcaacca aaagttggta cgatcctcat atg aat gaa cgc aca 115 Met Asn Glu Arg Thr 1 5 tcg gat gca ttt gac gcc ctc ctt gtg ctc tcc ttc ggt ggt ccc gaa 163 Ser Asp Ala Phe Asp Ala Leu Leu Val Leu Ser Phe Gly Gly Pro Glu 10 15 20 ggg cac gag gag gtt cgt ccg ttt ttg gag aat gtc act cac gga agg 211 Gly His Glu Glu Val Arg Pro Phe Leu Glu Asn Val Thr His Gly Arg 25 30 35 ggg att ccg ccg gaa cgt cta gat gaa gtg gcg gtt cat tac cac cac 259 Gly Ile Pro Pro Glu Arg Leu Asp Glu Val Ala Val His Tyr His His 40 45 50 ttc ggt ggt atc agc ccc atc aat gcg ctg aac agg gaa att atc gcc 307 Phe Gly Gly Ile Ser Pro Ile Asn Ala Leu Asn Arg Glu Ile Ile Ala 55 60 65 aat gtg gaa aaa gaa ttg gcg tct cgc gat cac aag ctg cct gtt tat 355 Asn Val Glu Lys Glu Leu Ala Ser Arg Asp His Lys Leu Pro Val Tyr 70 75 80 85 ttt ggt aac cgc aac tgg aag ccg ttt gat aat gag gcc gct gaa caa 403 Phe Gly Asn Arg Asn Trp Lys Pro Phe Asp Asn Glu Ala Ala Glu Gln 90 95 100 atg gct gat gac ggc gtg aaa aac gcg ctg gtg ttg gca act tcc gct 451 Met Ala Asp Asp Gly Val Lys Asn Ala Leu Val Leu Ala Thr Ser Ala 105 110 115 tgg ggt ggc tac tcc ggt tgt cgg cag tac cag gaa gat att cag ggc 499 Trp Gly Gly Tyr Ser Gly Cys Arg Gln Tyr Gln Glu Asp Ile Gln Gly 120 125 130 atg atc aag cac ctg gag tct cag ggg cag tcg atc acg ttc acc aag 547 Met Ile Lys His Leu Glu Ser Gln Gly Gln Ser Ile Thr Phe Thr Lys 135 140 145 ctg cgt cag ttc tac gat cac cct cgt ttt gtc tcc acc atg gct caa 595 Leu Arg Gln Phe Tyr Asp His Pro Arg Phe Val Ser Thr Met Ala Gln 150 155 160 165 ttg gtt cag gat tcc tac gcg aag ctt ccc gat gag ctg cga gat gag 643 Leu Val Gln Asp Ser Tyr Ala Lys Leu Pro Asp Glu Leu Arg Asp Glu 170 175 180 gcg cgt ctg gtc ttc acc gcg cac tcc att cca ctg act gcg gac aat 691 Ala Arg Leu Val Phe Thr Ala His Ser Ile Pro Leu Thr Ala Asp Asn 185 190 195 gct gcg gga acc cct gag gat ggc tcc ttg tat tcc aca cag gtc aag 739 Ala Ala Gly Thr Pro Glu Asp Gly Ser Leu Tyr Ser Thr Gln Val Lys 200 205 210 gaa gcg tca gca ctg att gct gag gct gtt ggt gtg tca gat ttt gat 787 Glu Ala Ser Ala Leu Ile Ala Glu Ala Val Gly Val Ser Asp Phe Asp 215 220 225 gtg gtg tgg cag tcc cgc tcg ggt agc ccg cac act ccg tgg ctg gag 835 Val Val Trp Gln Ser Arg Ser Gly Ser Pro His Thr Pro Trp Leu Glu 230 235 240 245 cct gac atc gtg gat cac gca gtg gag ctc aac gag aag ggt caa aaa 883 Pro Asp Ile Val Asp His Ala Val Glu Leu Asn Glu Lys Gly Gln Lys 250 255 260 gcg ctc gtt gtc tgc cct gta ggc ttt att tct gat cat atg gaa gtc 931 Ala Leu Val Val Cys Pro Val Gly Phe Ile Ser Asp His Met Glu Val 265 270 275 att tgg gat ctt gat tcc gag ctg atg gaa gaa gcc gag aag cgc aac 979 Ile Trp Asp Leu Asp Ser Glu Leu Met Glu Glu Ala Glu Lys Arg Asn 280 285 290 atg gtg gtc gag cgt gtc gct acc gtt ggc ccc acc gat gaa ttc gca 1027 Met Val Val Glu Arg Val Ala Thr Val Gly Pro Thr Asp Glu Phe Ala 295 300 305 gcc ctt gtg gtt gat ctc atc gag gag gca gag ctc aag cgc gtt atc 1075 Ala Leu Val Val Asp Leu Ile Glu Glu Ala Glu Leu Lys Arg Val Ile 310 315 320 325 gag cgc ctt gga aag ctg cca gca cgc gga agt tcc gtc aac ggc gca 1123 Glu Arg Leu Gly Lys Leu Pro Ala Arg Gly Ser Ser Val Asn Gly Ala 330 335 340 ccg tgt ggc gac ggc tgc tgt ggt acc gcc aag cat aaa acc gcg cgg 1171 Pro Cys Gly Asp Gly Cys Cys Gly Thr Ala Lys His Lys Thr Ala Arg 345 350 355 gtg aac ccc aac gct cgc tca gcg gcg cca gct gcc aac taggagtgat 1220 Val Asn Pro Asn Ala Arg Ser Ala Ala Pro Ala Ala Asn 360 365 370 agtccctcgc aaa 1233 <210> 796 <211> 370 <212> PRT <213> Corynebacterium glutamicum <400> 796 Met Asn Glu Arg Thr Ser Asp Ala Phe Asp Ala Leu Leu Val Leu Ser 1 5 10 15 Phe Gly Gly Pro Glu Gly His Glu Glu Val Arg Pro Phe Leu Glu Asn 20 25 30 Val Thr His Gly Arg Gly Ile Pro Pro Glu Arg Leu Asp Glu Val Ala 35 40 45 Val His Tyr His His Phe Gly Gly Ile Ser Pro Ile Asn Ala Leu Asn 50 55 60 Arg Glu Ile Ile Ala Asn Val Glu Lys Glu Leu Ala Ser Arg Asp His 65 70 75 80 Lys Leu Pro Val Tyr Phe Gly Asn Arg Asn Trp Lys Pro Phe Asp Asn 85 90 95 Glu Ala Ala Glu Gln Met Ala Asp Asp Gly Val Lys Asn Ala Leu Val 100 105 110 Leu Ala Thr Ser Ala Trp Gly Gly Tyr Ser Gly Cys Arg Gln Tyr Gln 115 120 125 Glu Asp Ile Gln Gly Met Ile Lys His Leu Glu Ser Gln Gly Gln Ser 130 135 140 Ile Thr Phe Thr Lys Leu Arg Gln Phe Tyr Asp His Pro Arg Phe Val 145 150 155 160 Ser Thr Met Ala Gln Leu Val Gln Asp Ser Tyr Ala Lys Leu Pro Asp 165 170 175 Glu Leu Arg Asp Glu Ala Arg Leu Val Phe Thr Ala His Ser Ile Pro 180 185 190 Leu Thr Ala Asp Asn Ala Ala Gly Thr Pro Glu Asp Gly Ser Leu Tyr 195 200 205 Ser Thr Gln Val Lys Glu Ala Ser Ala Leu Ile Ala Glu Ala Val Gly 210 215 220 Val Ser Asp Phe Asp Val Val Trp Gln Ser Arg Ser Gly Ser Pro His 225 230 235 240 Thr Pro Trp Leu Glu Pro Asp Ile Val Asp His Ala Val Glu Leu Asn 245 250 255 Glu Lys Gly Gln Lys Ala Leu Val Val Cys Pro Val Gly Phe Ile Ser 260 265 270 Asp His Met Glu Val Ile Trp Asp Leu Asp Ser Glu Leu Met Glu Glu 275 280 285 Ala Glu Lys Arg Asn Met Val Val Glu Arg Val Ala Thr Val Gly Pro 290 295 300 Thr Asp Glu Phe Ala Ala Leu Val Val Asp Leu Ile Glu Glu Ala Glu 305 310 315 320 Leu Lys Arg Val Ile Glu Arg Leu Gly Lys Leu Pro Ala Arg Gly Ser 325 330 335 Ser Val Asn Gly Ala Pro Cys Gly Asp Gly Cys Cys Gly Thr Ala Lys 340 345 350 His Lys Thr Ala Arg Val Asn Pro Asn Ala Arg Ser Ala Ala Pro Ala 355 360 365 Ala Asn 370 <210> 797 <211> 810 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(787) <223> RXA00624 <400> 797 tccatgacgt tttgaatgga aaatctccat ttgtggagtt agaagaagac cactagtttt 60 caacaggacg acaacggccg gacatgcgac aatacaatgc atg tcc ggc cgt ctt 115 Met Ser Gly Arg Leu 1 5 ctt gtt tca gtt tct agt att ttc gac cag acc cga tcg gcg gct gac 163 Leu Val Ser Val Ser Ser Ile Phe Asp Gln Thr Arg Ser Ala Ala Asp 10 15 20 agg ctc att tca gac ctg cga gcc gac ggc atc gag gtc tca tta ctt 211 Arg Leu Ile Ser Asp Leu Arg Ala Asp Gly Ile Glu Val Ser Leu Leu 25 30 35 gtc gca ccc cgc atc gat ggg gac tgg cgt ctc gcc aaa gac aaa ggg 259 Val Ala Pro Arg Ile Asp Gly Asp Trp Arg Leu Ala Lys Asp Lys Gly 40 45 50 acc ctc gcg tgg atg gaa caa caa cgc gaa cgc ggc cac gaa ctc atc 307 Thr Leu Ala Trp Met Glu Gln Gln Arg Glu Arg Gly His Glu Leu Ile 55 60 65 ctc aac ggt ttc gac caa gca gtt cag gga cgt cgc tca gaa ttc gcc 355 Leu Asn Gly Phe Asp Gln Ala Val Gln Gly Arg Arg Ser Glu Phe Ala 70 75 80 85 aac ctt gaa cgg cac gaa gca cgt ctt cgc ctt acc ggt gcc att agg 403 Asn Leu Glu Arg His Glu Ala Arg Leu Arg Leu Thr Gly Ala Ile Arg 90 95 100 caa atg cag aaa att ggc ttc gaa ttc caa atc ttt gcc cca cct cgt 451 Gln Met Gln Lys Ile Gly Phe Glu Phe Gln Ile Phe Ala Pro Pro Arg 105 110 115 tgg aga atg tca gaa ggc acc ttc gcg gta ctc cca gaa ttt gat ttc 499 Trp Arg Met Ser Glu Gly Thr Phe Ala Val Leu Pro Glu Phe Asp Phe 120 125 130 aac gtc gcc gcc tcg acc agg gga tta cat aac ctc gac acc ggc gaa 547 Asn Val Ala Ala Ser Thr Arg Gly Leu His Asn Leu Asp Thr Gly Glu 135 140 145 ttc ttg gcg tgt aga aac ctc tcc gtg ggt gaa ggt ttt ggt gct gca 595 Phe Leu Ala Cys Arg Asn Leu Ser Val Gly Glu Gly Phe Gly Ala Ala 150 155 160 165 aaa tgg tgg cgc aag aat gtc atc aag gct gtc act cgt gga gcg gaa 643 Lys Trp Trp Arg Lys Asn Val Ile Lys Ala Val Thr Arg Gly Ala Glu 170 175 180 aaa gga aat aca gtg cgc ttg tcc gca tcg gcg cga aat ctc acc aac 691 Lys Gly Asn Thr Val Arg Leu Ser Ala Ser Ala Arg Asn Leu Thr Asn 185 190 195 cct aaa gtc gca gct gac ttc cgg gaa gct gca tta gct gcc ttg gat 739 Pro Lys Val Ala Ala Asp Phe Arg Glu Ala Ala Leu Ala Ala Leu Asp 200 205 210 ttg ggt gct cag gtg caa acc tat tct cag gcg gcc gca caa ctg gcc 787 Leu Gly Ala Gln Val Gln Thr Tyr Ser Gln Ala Ala Ala Gln Leu Ala 215 220 225 tagttgggga ggttcggggc acc 810 <210> 798 <211> 229 <212> PRT <213> Corynebacterium glutamicum <400> 798 Met Ser Gly Arg Leu Leu Val Ser Val Ser Ser Ile Phe Asp Gln Thr 1 5 10 15 Arg Ser Ala Ala Asp Arg Leu Ile Ser Asp Leu Arg Ala Asp Gly Ile 20 25 30 Glu Val Ser Leu Leu Val Ala Pro Arg Ile Asp Gly Asp Trp Arg Leu 35 40 45 Ala Lys Asp Lys Gly Thr Leu Ala Trp Met Glu Gln Gln Arg Glu Arg 50 55 60 Gly His Glu Leu Ile Leu Asn Gly Phe Asp Gln Ala Val Gln Gly Arg 65 70 75 80 Arg Ser Glu Phe Ala Asn Leu Glu Arg His Glu Ala Arg Leu Arg Leu 85 90 95 Thr Gly Ala Ile Arg Gln Met Gln Lys Ile Gly Phe Glu Phe Gln Ile 100 105 110 Phe Ala Pro Pro Arg Trp Arg Met Ser Glu Gly Thr Phe Ala Val Leu 115 120 125 Pro Glu Phe Asp Phe Asn Val Ala Ala Ser Thr Arg Gly Leu His Asn 130 135 140 Leu Asp Thr Gly Glu Phe Leu Ala Cys Arg Asn Leu Ser Val Gly Glu 145 150 155 160 Gly Phe Gly Ala Ala Lys Trp Trp Arg Lys Asn Val Ile Lys Ala Val 165 170 175 Thr Arg Gly Ala Glu Lys Gly Asn Thr Val Arg Leu Ser Ala Ser Ala 180 185 190 Arg Asn Leu Thr Asn Pro Lys Val Ala Ala Asp Phe Arg Glu Ala Ala 195 200 205 Leu Ala Ala Leu Asp Leu Gly Ala Gln Val Gln Thr Tyr Ser Gln Ala 210 215 220 Ala Ala Gln Leu Ala 225 <210> 799 <211> 956 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(933) <223> RXA00306 <400> 799 gat tcc ggc att ccc acg cag ttg gtg gag ggc agc tgg ttt gaa ccg 48 Asp Ser Gly Ile Pro Thr Gln Leu Val Glu Gly Ser Trp Phe Glu Pro 1 5 10 15 gtt cgc ggg cgc acc ttt gac cgc atc atc gcc aac ccg ccg ttc gtg 96 Val Arg Gly Arg Thr Phe Asp Arg Ile Ile Ala Asn Pro Pro Phe Val 20 25 30 gtg gga cca ccg gaa att ggg cat gtg tac cgc gat tcc ggc atg gat 144 Val Gly Pro Pro Glu Ile Gly His Val Tyr Arg Asp Ser Gly Met Asp 35 40 45 cta gac ggc gcg acc gcg ttg gtg gtc aaa gaa gcc tgc gcg cat ctc 192 Leu Asp Gly Ala Thr Ala Leu Val Val Lys Glu Ala Cys Ala His Leu 50 55 60 aac cct ggt ggc acc gct cac ctg ctc ggc gca tgg gtg cat tcc gcg 240 Asn Pro Gly Gly Thr Ala His Leu Leu Gly Ala Trp Val His Ser Ala 65 70 75 80 gat caa tcg tgg cag cag cgc gtt gca gaa tgg ttg ccg gat aac ggt 288 Asp Gln Ser Trp Gln Gln Arg Val Ala Glu Trp Leu Pro Asp Asn Gly 85 90 95 tat gtt gct tgg gtt att gag cgc gac gcc gtg agc ccc gcg cag tat 336 Tyr Val Ala Trp Val Ile Glu Arg Asp Ala Val Ser Pro Ala Gln Tyr 100 105 110 gtg ggc acg tgg ctt agt gat gag tcc ctc gat ctg cgt agc ccc gag 384 Val Gly Thr Trp Leu Ser Asp Glu Ser Leu Asp Leu Arg Ser Pro Glu 115 120 125 gca gca gca cgc acc acc gcg tgg ctt aac cac ttt gaa aaa gcc aag 432 Ala Ala Ala Arg Thr Thr Ala Trp Leu Asn His Phe Glu Lys Ala Lys 130 135 140 gtt caa ggc gtt ggt ttt ggt ttc atc gcc atc caa cgt ctg gag gaa 480 Val Gln Gly Val Gly Phe Gly Phe Ile Ala Ile Gln Arg Leu Glu Glu 145 150 155 160 gac gag gcg gat gag aaa tcc gat atc ttg gct gaa tcc atg acc cag 528 Asp Glu Ala Asp Glu Lys Ser Asp Ile Leu Ala Glu Ser Met Thr Gln 165 170 175 tac ttc gag gat cct ctc ggc cct gaa att gag gag tac ttc acc cgc 576 Tyr Phe Glu Asp Pro Leu Gly Pro Glu Ile Glu Glu Tyr Phe Thr Arg 180 185 190 acc gca tgg ctt cgt gaa caa act cgc gat tcc att ctg agc tcc cgc 624 Thr Ala Trp Leu Arg Glu Gln Thr Arg Asp Ser Ile Leu Ser Ser Arg 195 200 205 ttc aaa gtt cgc cct ggc gtg gcc cgg gaa caa atc agc ctg gcc gat 672 Phe Lys Val Arg Pro Gly Val Ala Arg Glu Gln Ile Ser Leu Ala Asp 210 215 220 gcg gaa gaa ggc atg ggc ttt agt cct gtc acg ttg agg ctc acc cgc 720 Ala Glu Glu Gly Met Gly Phe Ser Pro Val Thr Leu Arg Leu Thr Arg 225 230 235 240 acc gat ggt cct cgt tgg tcc cat gat gtt gat gag cat gtg gct tcc 768 Thr Asp Gly Pro Arg Trp Ser His Asp Val Asp Glu His Val Ala Ser 245 250 255 atc gtc gca gga ctt aac cca cat gga ctc ccc ttt gaa gaa atc ctg 816 Ile Val Ala Gly Leu Asn Pro His Gly Leu Pro Phe Glu Glu Ile Leu 260 265 270 gaa atg tac gcg atg gct caa ggt atc gag gga gaa tcc ctg cac aac 864 Glu Met Tyr Ala Met Ala Gln Gly Ile Glu Gly Glu Ser Leu His Asn 275 280 285 ggc gcc att gcg gcg ttg gtg gat ctc atc cgc cac gga ttg gtg ttg 912 Gly Ala Ile Ala Ala Leu Val Asp Leu Ile Arg His Gly Leu Val Leu 290 295 300 ccc gct gat ctt ctc gat tct taaataagga ctgattgtga aag 956 Pro Ala Asp Leu Leu Asp Ser 305 310 <210> 800 <211> 311 <212> PRT <213> Corynebacterium glutamicum <400> 800 Asp Ser Gly Ile Pro Thr Gln Leu Val Glu Gly Ser Trp Phe Glu Pro 1 5 10 15 Val Arg Gly Arg Thr Phe Asp Arg Ile Ile Ala Asn Pro Pro Phe Val 20 25 30 Val Gly Pro Pro Glu Ile Gly His Val Tyr Arg Asp Ser Gly Met Asp 35 40 45 Leu Asp Gly Ala Thr Ala Leu Val Val Lys Glu Ala Cys Ala His Leu 50 55 60 Asn Pro Gly Gly Thr Ala His Leu Leu Gly Ala Trp Val His Ser Ala 65 70 75 80 Asp Gln Ser Trp Gln Gln Arg Val Ala Glu Trp Leu Pro Asp Asn Gly 85 90 95 Tyr Val Ala Trp Val Ile Glu Arg Asp Ala Val Ser Pro Ala Gln Tyr 100 105 110 Val Gly Thr Trp Leu Ser Asp Glu Ser Leu Asp Leu Arg Ser Pro Glu 115 120 125 Ala Ala Ala Arg Thr Thr Ala Trp Leu Asn His Phe Glu Lys Ala Lys 130 135 140 Val Gln Gly Val Gly Phe Gly Phe Ile Ala Ile Gln Arg Leu Glu Glu 145 150 155 160 Asp Glu Ala Asp Glu Lys Ser Asp Ile Leu Ala Glu Ser Met Thr Gln 165 170 175 Tyr Phe Glu Asp Pro Leu Gly Pro Glu Ile Glu Glu Tyr Phe Thr Arg 180 185 190 Thr Ala Trp Leu Arg Glu Gln Thr Arg Asp Ser Ile Leu Ser Ser Arg 195 200 205 Phe Lys Val Arg Pro Gly Val Ala Arg Glu Gln Ile Ser Leu Ala Asp 210 215 220 Ala Glu Glu Gly Met Gly Phe Ser Pro Val Thr Leu Arg Leu Thr Arg 225 230 235 240 Thr Asp Gly Pro Arg Trp Ser His Asp Val Asp Glu His Val Ala Ser 245 250 255 Ile Val Ala Gly Leu Asn Pro His Gly Leu Pro Phe Glu Glu Ile Leu 260 265 270 Glu Met Tyr Ala Met Ala Gln Gly Ile Glu Gly Glu Ser Leu His Asn 275 280 285 Gly Ala Ile Ala Ala Leu Val Asp Leu Ile Arg His Gly Leu Val Leu 290 295 300 Pro Ala Asp Leu Leu Asp Ser 305 310 <210> 801 <211> 1263 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1240) <223> RXA00884 <400> 801 catcttccgt ttcataccct gcactctacc ctgttcttag gaattcgcta tgtttaacat 60 caattaatca tgtatagggg gcaggcacta ggcttggggc atg tca gtt ttt ggt 115 Met Ser Val Phe Gly 1 5 gtg tat att cat gtg ccg ttt tgt tca act cgg tgc ggt tat tgc gat 163 Val Tyr Ile His Val Pro Phe Cys Ser Thr Arg Cys Gly Tyr Cys Asp 10 15 20 ttc aac acc tat act gct ggg gaa tta ggt agt act gca ggc ccg gac 211 Phe Asn Thr Tyr Thr Ala Gly Glu Leu Gly Ser Thr Ala Gly Pro Asp 25 30 35 acc tat ctt gac tcg ttg gaa gtt gag ttg gag atg gct gtg gct tcg 259 Thr Tyr Leu Asp Ser Leu Glu Val Glu Leu Glu Met Ala Val Ala Ser 40 45 50 ctg gat aat cct cgg cag gcg gaa act atc ttt att ggc ggg ggt acc 307 Leu Asp Asn Pro Arg Gln Ala Glu Thr Ile Phe Ile Gly Gly Gly Thr 55 60 65 ccg tcg ttg att ggt gcg gac ggt ttg gcc agg gtt ttg ggg gct gtg 355 Pro Ser Leu Ile Gly Ala Asp Gly Leu Ala Arg Val Leu Gly Ala Val 70 75 80 85 cgc aat act ttt ggc att gcg gat ggt gcg gaa gtc acc acg gag tcc 403 Arg Asn Thr Phe Gly Ile Ala Asp Gly Ala Glu Val Thr Thr Glu Ser 90 95 100 aat ccg gag tct acc tcg cct gag ttt ttt gat ggc ctg cgt gag gcg 451 Asn Pro Glu Ser Thr Ser Pro Glu Phe Phe Asp Gly Leu Arg Glu Ala 105 110 115 ggc tac aac agg att tcg tta ggg atg cag tcg gcg tcg tca agc gtt 499 Gly Tyr Asn Arg Ile Ser Leu Gly Met Gln Ser Ala Ser Ser Ser Val 120 125 130 ttg aag gtg ctg gac cgc acg cac acc cca ggg cgc ccg gtg gcg gcg 547 Leu Lys Val Leu Asp Arg Thr His Thr Pro Gly Arg Pro Val Ala Ala 135 140 145 gcc aag gag gca cgt gag gcg ggg ttt gag cat gtc aat ttg gac atg 595 Ala Lys Glu Ala Arg Glu Ala Gly Phe Glu His Val Asn Leu Asp Met 150 155 160 165 att tat ggc acg ccg aca gag acc gat gat gat gtc cgc aag acg ctg 643 Ile Tyr Gly Thr Pro Thr Glu Thr Asp Asp Asp Val Arg Lys Thr Leu 170 175 180 aat gcg gtg ctc gaa gcg aac gtg gat cac gtg tct gcc tat tcc ttg 691 Asn Ala Val Leu Glu Ala Asn Val Asp His Val Ser Ala Tyr Ser Leu 185 190 195 atc gtg aaa gat ggc acg gcg atg gcg cgc aag gtg cac aag ggc gag 739 Ile Val Lys Asp Gly Thr Ala Met Ala Arg Lys Val His Lys Gly Glu 200 205 210 ctg cca gcg ccg gac gag gat gtc tac gct gat cgt ttt gag ctt atc 787 Leu Pro Ala Pro Asp Glu Asp Val Tyr Ala Asp Arg Phe Glu Leu Ile 215 220 225 gac gct cgc ctg cgc tca gct ggt ttc gat tgg tac gag gtg tcc aac 835 Asp Ala Arg Leu Arg Ser Ala Gly Phe Asp Trp Tyr Glu Val Ser Asn 230 235 240 245 tgg gcg aaa ccc ggc gga gaa tgc aag cac aac atg ggc tat tgg gtc 883 Trp Ala Lys Pro Gly Gly Glu Cys Lys His Asn Met Gly Tyr Trp Val 250 255 260 gac ggc gac tgg tgg ggc gcg ggc ccg ggc gcg cac tcg cac atc ggc 931 Asp Gly Asp Trp Trp Gly Ala Gly Pro Gly Ala His Ser His Ile Gly 265 270 275 gac cgc cgc ttc tac aac atc aag cac cca gcg cgt tac tcc gcg cag 979 Asp Arg Arg Phe Tyr Asn Ile Lys His Pro Ala Arg Tyr Ser Ala Gln 280 285 290 att gcg gcc ggc gag ctg ccc att aag gaa aca gag cgg ctg acg gcg 1027 Ile Ala Ala Gly Glu Leu Pro Ile Lys Glu Thr Glu Arg Leu Thr Ala 295 300 305 gaa gat cac cac acc gag cgc gtc atg ctt ggt ttg cgc ctg aaa caa 1075 Glu Asp His His Thr Glu Arg Val Met Leu Gly Leu Arg Leu Lys Gln 310 315 320 325 ggc gtg ccg ctg aac ctt ttc gca ccc gca gcg cgc ccg gtc atc gac 1123 Gly Val Pro Leu Asn Leu Phe Ala Pro Ala Ala Arg Pro Val Ile Asp 330 335 340 cgt cat atc gca ggg ggc ctg ctg cac gtc aat gcg ctg ggc aac ctg 1171 Arg His Ile Ala Gly Gly Leu Leu His Val Asn Ala Leu Gly Asn Leu 345 350 355 gcg gtg acc gat gcg gga cgt ttg ctt gcc gac ggc atc atc gcc gac 1219 Ala Val Thr Asp Ala Gly Arg Leu Leu Ala Asp Gly Ile Ile Ala Asp 360 365 370 att ttg ctt agt gaa gaa gac taaatattta gtagggttac aga 1263 Ile Leu Leu Ser Glu Glu Asp 375 380 <210> 802 <211> 380 <212> PRT <213> Corynebacterium glutamicum <400> 802 Met Ser Val Phe Gly Val Tyr Ile His Val Pro Phe Cys Ser Thr Arg 1 5 10 15 Cys Gly Tyr Cys Asp Phe Asn Thr Tyr Thr Ala Gly Glu Leu Gly Ser 20 25 30 Thr Ala Gly Pro Asp Thr Tyr Leu Asp Ser Leu Glu Val Glu Leu Glu 35 40 45 Met Ala Val Ala Ser Leu Asp Asn Pro Arg Gln Ala Glu Thr Ile Phe 50 55 60 Ile Gly Gly Gly Thr Pro Ser Leu Ile Gly Ala Asp Gly Leu Ala Arg 65 70 75 80 Val Leu Gly Ala Val Arg Asn Thr Phe Gly Ile Ala Asp Gly Ala Glu 85 90 95 Val Thr Thr Glu Ser Asn Pro Glu Ser Thr Ser Pro Glu Phe Phe Asp 100 105 110 Gly Leu Arg Glu Ala Gly Tyr Asn Arg Ile Ser Leu Gly Met Gln Ser 115 120 125 Ala Ser Ser Ser Val Leu Lys Val Leu Asp Arg Thr His Thr Pro Gly 130 135 140 Arg Pro Val Ala Ala Ala Lys Glu Ala Arg Glu Ala Gly Phe Glu His 145 150 155 160 Val Asn Leu Asp Met Ile Tyr Gly Thr Pro Thr Glu Thr Asp Asp Asp 165 170 175 Val Arg Lys Thr Leu Asn Ala Val Leu Glu Ala Asn Val Asp His Val 180 185 190 Ser Ala Tyr Ser Leu Ile Val Lys Asp Gly Thr Ala Met Ala Arg Lys 195 200 205 Val His Lys Gly Glu Leu Pro Ala Pro Asp Glu Asp Val Tyr Ala Asp 210 215 220 Arg Phe Glu Leu Ile Asp Ala Arg Leu Arg Ser Ala Gly Phe Asp Trp 225 230 235 240 Tyr Glu Val Ser Asn Trp Ala Lys Pro Gly Gly Glu Cys Lys His Asn 245 250 255 Met Gly Tyr Trp Val Asp Gly Asp Trp Trp Gly Ala Gly Pro Gly Ala 260 265 270 His Ser His Ile Gly Asp Arg Arg Phe Tyr Asn Ile Lys His Pro Ala 275 280 285 Arg Tyr Ser Ala Gln Ile Ala Ala Gly Glu Leu Pro Ile Lys Glu Thr 290 295 300 Glu Arg Leu Thr Ala Glu Asp His His Thr Glu Arg Val Met Leu Gly 305 310 315 320 Leu Arg Leu Lys Gln Gly Val Pro Leu Asn Leu Phe Ala Pro Ala Ala 325 330 335 Arg Pro Val Ile Asp Arg His Ile Ala Gly Gly Leu Leu His Val Asn 340 345 350 Ala Leu Gly Asn Leu Ala Val Thr Asp Ala Gly Arg Leu Leu Ala Asp 355 360 365 Gly Ile Ile Ala Asp Ile Leu Leu Ser Glu Glu Asp 370 375 380 <210> 803 <211> 522 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(499) <223> RXN02503 <400> 803 gcagcaccgg caaccacgtc cgtcaacgcg tcagaactgc cggatgcggg tatcgtcgca 60 ttcgtgaacg caccttctgc cacacaaacg agggagtaac atg acc tta aaa att 115 Met Thr Leu Lys Ile 1 5 ggt acc cga gga tcc aaa ctt gcc acc acc caa gct ggc acc atc cgc 163 Gly Thr Arg Gly Ser Lys Leu Ala Thr Thr Gln Ala Gly Thr Ile Arg 10 15 20 gac cag ctg aaa cac tac gga cgc gac gct gaa ctg cac atc gtg acc 211 Asp Gln Leu Lys His Tyr Gly Arg Asp Ala Glu Leu His Ile Val Thr 25 30 35 acc cct ggt gat gtc aac atg tcc cca gtc gag cgt atc ggc gtc ggc 259 Thr Pro Gly Asp Val Asn Met Ser Pro Val Glu Arg Ile Gly Val Gly 40 45 50 gtg ttc acc cag gcg ctg cgc gat gtg ttg cat tcc ggt gaa tgc gat 307 Val Phe Thr Gln Ala Leu Arg Asp Val Leu His Ser Gly Glu Cys Asp 55 60 65 gtg gct gtg cac tcc atg aag gat ctg ccg acc gcc acc gat cct cga 355 Val Ala Val His Ser Met Lys Asp Leu Pro Thr Ala Thr Asp Pro Arg 70 75 80 85 ttc cac ctg gtc gtg cca act cgt gcg gac tcg cgc gag gcc ctt atc 403 Phe His Leu Val Val Pro Thr Arg Ala Asp Ser Arg Glu Ala Leu Ile 90 95 100 gcc cgc gac ggc ctg act ctg gct gag ctt cca gaa agg cgc aaa ggt 451 Ala Arg Asp Gly Leu Thr Leu Ala Glu Leu Pro Glu Arg Arg Lys Gly 105 110 115 ggg aac ttc cgc tcc tcg acg cat ctc cca gct caa ggc aat ccg ccc 499 Gly Asn Phe Arg Ser Ser Thr His Leu Pro Ala Gln Gly Asn Pro Pro 120 125 130 tgacctggag attctcccac tgc 522 <210> 804 <211> 133 <212> PRT <213> Corynebacterium glutamicum <400> 804 Met Thr Leu Lys Ile Gly Thr Arg Gly Ser Lys Leu Ala Thr Thr Gln 1 5 10 15 Ala Gly Thr Ile Arg Asp Gln Leu Lys His Tyr Gly Arg Asp Ala Glu 20 25 30 Leu His Ile Val Thr Thr Pro Gly Asp Val Asn Met Ser Pro Val Glu 35 40 45 Arg Ile Gly Val Gly Val Phe Thr Gln Ala Leu Arg Asp Val Leu His 50 55 60 Ser Gly Glu Cys Asp Val Ala Val His Ser Met Lys Asp Leu Pro Thr 65 70 75 80 Ala Thr Asp Pro Arg Phe His Leu Val Val Pro Thr Arg Ala Asp Ser 85 90 95 Arg Glu Ala Leu Ile Ala Arg Asp Gly Leu Thr Leu Ala Glu Leu Pro 100 105 110 Glu Arg Arg Lys Gly Gly Asn Phe Arg Ser Ser Thr His Leu Pro Ala 115 120 125 Gln Gly Asn Pro Pro 130 <210> 805 <211> 558 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(535) <223> FRXA02503 <220> <221> misc_feature <222> 409, 421 <223> n = a, c, t, or g <220> <221> VARIANT <222> 96 <223> Xaa = Ser <220> <221> VARIANT <222> 99 <223> Xaa = Gly <220> <221> VARIANT <222> 106 <223> Xaa = Ala or Pro <220> <221> VARIANT <222> 107 <223> Xaa = Asp or Glu <220> <221> VARIANT <222> 109 <223> Xaa = Gly or Trp <220> <221> VARIANT <222> 110 <223> Xaa = Leu <220> <221> VARIANT <222> 112 <223> Xaa = Phe <220> <221> VARIANT <222> 114 <223> Xaa = Lys <220> <221> VARIANT <222> 115 <223> Xaa = Gly or Ala <220> <221> VARIANT <222> 116 <223> Xaa = Glu or Gln <400> 805 gcagcaccgg caaccacgtc cgtcaacgcg tcagaactgc cggatgcggg tatcgtcgca 60 ttcgtgaacg caccttctgc cacacaaacg agggagtaac atg acc tta aaa att 115 Met Thr Leu Lys Ile 1 5 ggt acc cga gga tcc aaa ctt gcc acc acc caa gct ggc acc atc cgc 163 Gly Thr Arg Gly Ser Lys Leu Ala Thr Thr Gln Ala Gly Thr Ile Arg 10 15 20 gac cag ctg aaa cac tac gga cgc gac gct gaa ctg cac atc gtg acc 211 Asp Gln Leu Lys His Tyr Gly Arg Asp Ala Glu Leu His Ile Val Thr 25 30 35 acc cct ggt gat gtc aac atg tcc cca gtc gag cgt atc ggc gtc ggc 259 Thr Pro Gly Asp Val Asn Met Ser Pro Val Glu Arg Ile Gly Val Gly 40 45 50 gtg ttc acc cag gcg ctg cgc gat gtg ttg cat tcc ggt gaa tgc gat 307 Val Phe Thr Gln Ala Leu Arg Asp Val Leu His Ser Gly Glu Cys Asp 55 60 65 gtg gct gtg cac tcc atg aag gat ctg ccg acc gcc acc gat cct cga 355 Val Ala Val His Ser Met Lys Asp Leu Pro Thr Ala Thr Asp Pro Arg 70 75 80 85 ttc cac ctg gtc gtg cca act cgt gcg gac tck cgc cga ggs cct tat 403 Phe His Leu Val Val Pro Thr Arg Ala Asp Xaa Arg Arg Xaa Pro Tyr 90 95 100 cgc ccn cga cgg sct gan ttt kgg ttr agc tty caa aar gsg saa agg 451 Arg Pro Arg Arg Xaa Xaa Phe Xaa Xaa Ser Xaa Gln Xaa Xaa Xaa Arg 105 110 115 tgg gaa ctt tcc gct cct cga cgc atc tcc cag ctc aag gca atc cgc 499 Trp Glu Leu Ser Ala Pro Arg Arg Ile Ser Gln Leu Lys Ala Ile Arg 120 125 130 cct gac ctg gag att ctc cca ctt gcg cgg aaa cat tgacaccggc 545 Pro Asp Leu Glu Ile Leu Pro Leu Ala Arg Lys His 135 140 145 atgggcaagg tca 558 <210> 806 <211> 145 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 96 <223> Xaa = Ser <220> <221> VARIANT <222> 99 <223> Xaa = Gly <220> <221> VARIANT <222> 106 <223> Xaa = Ala or Pro <220> <221> VARIANT <222> 107 <223> Xaa = Asp or Glu <220> <221> VARIANT <222> 109 <223> Xaa = Gly or Trp <220> <221> VARIANT <222> 110 <223> Xaa = Leu <220> <221> VARIANT <222> 112 <223> Xaa = Phe <220> <221> VARIANT <222> 114 <223> Xaa = Lys <220> <221> VARIANT <222> 115 <223> Xaa = Gly or Ala <220> <221> VARIANT <222> 116 <223> Xaa = Glu or Gln <400> 806 Met Thr Leu Lys Ile Gly Thr Arg Gly Ser Lys Leu Ala Thr Thr Gln 1 5 10 15 Ala Gly Thr Ile Arg Asp Gln Leu Lys His Tyr Gly Arg Asp Ala Glu 20 25 30 Leu His Ile Val Thr Thr Pro Gly Asp Val Asn Met Ser Pro Val Glu 35 40 45 Arg Ile Gly Val Gly Val Phe Thr Gln Ala Leu Arg Asp Val Leu His 50 55 60 Ser Gly Glu Cys Asp Val Ala Val His Ser Met Lys Asp Leu Pro Thr 65 70 75 80 Ala Thr Asp Pro Arg Phe His Leu Val Val Pro Thr Arg Ala Asp Xaa 85 90 95 Arg Arg Xaa Pro Tyr Arg Pro Arg Arg Xaa Xaa Phe Xaa Xaa Ser Xaa 100 105 110 Gln Xaa Xaa Xaa Arg Trp Glu Leu Ser Ala Pro Arg Arg Ile Ser Gln 115 120 125 Leu Lys Ala Ile Arg Pro Asp Leu Glu Ile Leu Pro Leu Ala Arg Lys 130 135 140 His 145 <210> 807 <211> 1245 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1222) <223> RXA00377 <400> 807 aatggcgctc gggcagggcg cgcaagtact aaccagcaat tcccaagccc aaaaacccct 60 cccatatagt tctttttact gatgcattgt cctcaattag gtg tgg ctt ctt ttc 115 Val Trp Leu Leu Phe 1 5 cta aat tgg gat aaa tgg ggc aag att gag cgc atg tct gct ctt act 163 Leu Asn Trp Asp Lys Trp Gly Lys Ile Glu Arg Met Ser Ala Leu Thr 10 15 20 att cca gct gcg cgt cgc acg cta aat aac gcg ccc att att gat gcc 211 Ile Pro Ala Ala Arg Arg Thr Leu Asn Asn Ala Pro Ile Ile Asp Ala 25 30 35 gct aat ggc aag acc ccg act cgc act ccg gtg tgg ttt atg cgc cag 259 Ala Asn Gly Lys Thr Pro Thr Arg Thr Pro Val Trp Phe Met Arg Gln 40 45 50 gcg ggt agg tcg ttg cct gag tac aag aag gtc cgt gag gga atc agc 307 Ala Gly Arg Ser Leu Pro Glu Tyr Lys Lys Val Arg Glu Gly Ile Ser 55 60 65 atg ttg gat tcc tgt ttc atg ccg gag ttg ttg gcg gag att act ttg 355 Met Leu Asp Ser Cys Phe Met Pro Glu Leu Leu Ala Glu Ile Thr Leu 70 75 80 85 cag ccg gtt cgt cgt cat gat gtg gat gct gcg att ttg ttc tct gac 403 Gln Pro Val Arg Arg His Asp Val Asp Ala Ala Ile Leu Phe Ser Asp 90 95 100 att gtg gtg ccg ttg cgt gct gcg ggt gtt ggt gtg gaa atc gtg gcg 451 Ile Val Val Pro Leu Arg Ala Ala Gly Val Gly Val Glu Ile Val Ala 105 110 115 ggt cgt gga cct gtg ttg gat gcg ccg gtg cgg agc cgt ggg gat gtg 499 Gly Arg Gly Pro Val Leu Asp Ala Pro Val Arg Ser Arg Gly Asp Val 120 125 130 ttg aat ctt cct att ttg gag ggc aac gtt ccg gag gtg gag cag ggt 547 Leu Asn Leu Pro Ile Leu Glu Gly Asn Val Pro Glu Val Glu Gln Gly 135 140 145 att ggc atc att ttg gat gag ttg tct gat tct cag gcg ttg att ggt 595 Ile Gly Ile Ile Leu Asp Glu Leu Ser Asp Ser Gln Ala Leu Ile Gly 150 155 160 165 ttt gct ggt gcg ccg ttt acg ttg gcg agt tac ttg gtt gag ggt ggt 643 Phe Ala Gly Ala Pro Phe Thr Leu Ala Ser Tyr Leu Val Glu Gly Gly 170 175 180 cct tcc aag aat cat gag aag acc aaa gca atg atg cat ggt gat cct 691 Pro Ser Lys Asn His Glu Lys Thr Lys Ala Met Met His Gly Asp Pro 185 190 195 gag acg tgg cat gcg ttg atg gct cgt ttg gtg ccg acg att gtg aat 739 Glu Thr Trp His Ala Leu Met Ala Arg Leu Val Pro Thr Ile Val Asn 200 205 210 tct ttg aag tcg cag atc gat gcg ggt atc gat gcg gtg cag ttg ttt 787 Ser Leu Lys Ser Gln Ile Asp Ala Gly Ile Asp Ala Val Gln Leu Phe 215 220 225 gat tcg tgg gct ggg ttc ctc act gag cgt gat tac acc gag ttc gtg 835 Asp Ser Trp Ala Gly Phe Leu Thr Glu Arg Asp Tyr Thr Glu Phe Val 230 235 240 245 ttg ccg tat tcc act gag att ttg gag gaa gtg ggc aag tac cag ctg 883 Leu Pro Tyr Ser Thr Glu Ile Leu Glu Glu Val Gly Lys Tyr Gln Leu 250 255 260 cct cgt att cac ttt ggt gtg ggt act ggt gag ttg ctt ggt gcg atg 931 Pro Arg Ile His Phe Gly Val Gly Thr Gly Glu Leu Leu Gly Ala Met 265 270 275 agc aag gct ggc tca gag gtc atg ggt gtg gat tgg cgg gtg ccg ttg 979 Ser Lys Ala Gly Ser Glu Val Met Gly Val Asp Trp Arg Val Pro Leu 280 285 290 gat aag gct gcg gag cgt att gct gcg gta tca ggt cct aag gtg ttg 1027 Asp Lys Ala Ala Glu Arg Ile Ala Ala Val Ser Gly Pro Lys Val Leu 295 300 305 cag ggt aac ctc gat cct gcg ttg ttg ttt gcg ggt cgc gca cct ttg 1075 Gln Gly Asn Leu Asp Pro Ala Leu Leu Phe Ala Gly Arg Ala Pro Leu 310 315 320 325 act aag gaa att gag cgc atc aag gca gag gct cag act gct gtt gat 1123 Thr Lys Glu Ile Glu Arg Ile Lys Ala Glu Ala Gln Thr Ala Val Asp 330 335 340 gca ggt cat gca acg ggc cat atc ttt aac ctt ggt cat ggt gtg ctt 1171 Ala Gly His Ala Thr Gly His Ile Phe Asn Leu Gly His Gly Val Leu 345 350 355 cct aat acg gtg gcg gaa gat att act gaa gcc gtc tcc atc att cat 1219 Pro Asn Thr Val Ala Glu Asp Ile Thr Glu Ala Val Ser Ile Ile His 360 365 370 tct taaactaaga ggagtttcat gcg 1245 Ser <210> 808 <211> 374 <212> PRT <213> Corynebacterium glutamicum <400> 808 Val Trp Leu Leu Phe Leu Asn Trp Asp Lys Trp Gly Lys Ile Glu Arg 1 5 10 15 Met Ser Ala Leu Thr Ile Pro Ala Ala Arg Arg Thr Leu Asn Asn Ala 20 25 30 Pro Ile Ile Asp Ala Ala Asn Gly Lys Thr Pro Thr Arg Thr Pro Val 35 40 45 Trp Phe Met Arg Gln Ala Gly Arg Ser Leu Pro Glu Tyr Lys Lys Val 50 55 60 Arg Glu Gly Ile Ser Met Leu Asp Ser Cys Phe Met Pro Glu Leu Leu 65 70 75 80 Ala Glu Ile Thr Leu Gln Pro Val Arg Arg His Asp Val Asp Ala Ala 85 90 95 Ile Leu Phe Ser Asp Ile Val Val Pro Leu Arg Ala Ala Gly Val Gly 100 105 110 Val Glu Ile Val Ala Gly Arg Gly Pro Val Leu Asp Ala Pro Val Arg 115 120 125 Ser Arg Gly Asp Val Leu Asn Leu Pro Ile Leu Glu Gly Asn Val Pro 130 135 140 Glu Val Glu Gln Gly Ile Gly Ile Ile Leu Asp Glu Leu Ser Asp Ser 145 150 155 160 Gln Ala Leu Ile Gly Phe Ala Gly Ala Pro Phe Thr Leu Ala Ser Tyr 165 170 175 Leu Val Glu Gly Gly Pro Ser Lys Asn His Glu Lys Thr Lys Ala Met 180 185 190 Met His Gly Asp Pro Glu Thr Trp His Ala Leu Met Ala Arg Leu Val 195 200 205 Pro Thr Ile Val Asn Ser Leu Lys Ser Gln Ile Asp Ala Gly Ile Asp 210 215 220 Ala Val Gln Leu Phe Asp Ser Trp Ala Gly Phe Leu Thr Glu Arg Asp 225 230 235 240 Tyr Thr Glu Phe Val Leu Pro Tyr Ser Thr Glu Ile Leu Glu Glu Val 245 250 255 Gly Lys Tyr Gln Leu Pro Arg Ile His Phe Gly Val Gly Thr Gly Glu 260 265 270 Leu Leu Gly Ala Met Ser Lys Ala Gly Ser Glu Val Met Gly Val Asp 275 280 285 Trp Arg Val Pro Leu Asp Lys Ala Ala Glu Arg Ile Ala Ala Val Ser 290 295 300 Gly Pro Lys Val Leu Gln Gly Asn Leu Asp Pro Ala Leu Leu Phe Ala 305 310 315 320 Gly Arg Ala Pro Leu Thr Lys Glu Ile Glu Arg Ile Lys Ala Glu Ala 325 330 335 Gln Thr Ala Val Asp Ala Gly His Ala Thr Gly His Ile Phe Asn Leu 340 345 350 Gly His Gly Val Leu Pro Asn Thr Val Ala Glu Asp Ile Thr Glu Ala 355 360 365 Val Ser Ile Ile His Ser 370 <210> 809 <211> 681 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(658) <223> RXN02504 <400> 809 cctcgattcc acctggtcgt gccaactcgt gcggactcgc gcgaggccct tatcgcccgc 60 gacggcctga ctctggctga gcttccagaa aggcgcaaag gtg gga act tcc gct 115 Val Gly Thr Ser Ala 1 5 cct cga cgc atc tcc cag ctc aag gca atc cgc cct gac ctg gag att 163 Pro Arg Arg Ile Ser Gln Leu Lys Ala Ile Arg Pro Asp Leu Glu Ile 10 15 20 ctc cca ctg cgc gga aac att gac acc ggc atg ggc aag gtc acc tcc 211 Leu Pro Leu Arg Gly Asn Ile Asp Thr Gly Met Gly Lys Val Thr Ser 25 30 35 ggt gaa ctc gat gct gtg atg ctc gcc tac gca ggc ctc acc cgc gtc 259 Gly Glu Leu Asp Ala Val Met Leu Ala Tyr Ala Gly Leu Thr Arg Val 40 45 50 ggc atg cag gac cgc gca acg gaa gtt ttc gac gcc gac atc atc atg 307 Gly Met Gln Asp Arg Ala Thr Glu Val Phe Asp Ala Asp Ile Ile Met 55 60 65 ccc gcc ccc gca cag ggc gca ctt gcg atc gaa tgc cgc gcc gac gac 355 Pro Ala Pro Ala Gln Gly Ala Leu Ala Ile Glu Cys Arg Ala Asp Asp 70 75 80 85 act gaa acc gtc cgc gcg ctc aac atg ctg atg cac gcc gac acg ttt 403 Thr Glu Thr Val Arg Ala Leu Asn Met Leu Met His Ala Asp Thr Phe 90 95 100 gtt tcc gcg gtt gca gaa cgc acc gtg ctc aac cgc ctc gaa gct ggc 451 Val Ser Ala Val Ala Glu Arg Thr Val Leu Asn Arg Leu Glu Ala Gly 105 110 115 tgt acc gcg cct gtc gca gcg cac gcc acc ttg gac ggc tac tcc ggc 499 Cys Thr Ala Pro Val Ala Ala His Ala Thr Leu Asp Gly Tyr Ser Gly 120 125 130 gac acc atg act ctc acc gcc ggc gtc tac gca ctt gac ggc tct gac 547 Asp Thr Met Thr Leu Thr Ala Gly Val Tyr Ala Leu Asp Gly Ser Asp 135 140 145 cag ctg gta ttc tcc gcc gaa ggt gac ggc gcc cgc cca gaa gag ctc 595 Gln Leu Val Phe Ser Ala Glu Gly Asp Gly Ala Arg Pro Glu Glu Leu 150 155 160 165 ggc gag ctc gtt gca caa cag ctt atc gac gcc gga gcc gcc aat ttg 643 Gly Glu Leu Val Ala Gln Gln Leu Ile Asp Ala Gly Ala Ala Asn Leu 170 175 180 ctc ggc gac cgc agc taattagggc ccgaaatttc cat 681 Leu Gly Asp Arg Ser 185 <210> 810 <211> 186 <212> PRT <213> Corynebacterium glutamicum <400> 810 Val Gly Thr Ser Ala Pro Arg Arg Ile Ser Gln Leu Lys Ala Ile Arg 1 5 10 15 Pro Asp Leu Glu Ile Leu Pro Leu Arg Gly Asn Ile Asp Thr Gly Met 20 25 30 Gly Lys Val Thr Ser Gly Glu Leu Asp Ala Val Met Leu Ala Tyr Ala 35 40 45 Gly Leu Thr Arg Val Gly Met Gln Asp Arg Ala Thr Glu Val Phe Asp 50 55 60 Ala Asp Ile Ile Met Pro Ala Pro Ala Gln Gly Ala Leu Ala Ile Glu 65 70 75 80 Cys Arg Ala Asp Asp Thr Glu Thr Val Arg Ala Leu Asn Met Leu Met 85 90 95 His Ala Asp Thr Phe Val Ser Ala Val Ala Glu Arg Thr Val Leu Asn 100 105 110 Arg Leu Glu Ala Gly Cys Thr Ala Pro Val Ala Ala His Ala Thr Leu 115 120 125 Asp Gly Tyr Ser Gly Asp Thr Met Thr Leu Thr Ala Gly Val Tyr Ala 130 135 140 Leu Asp Gly Ser Asp Gln Leu Val Phe Ser Ala Glu Gly Asp Gly Ala 145 150 155 160 Arg Pro Glu Glu Leu Gly Glu Leu Val Ala Gln Gln Leu Ile Asp Ala 165 170 175 Gly Ala Ala Asn Leu Leu Gly Asp Arg Ser 180 185 <210> 811 <211> 561 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(538) <223> FRXA02504 <400> 811 gcatctccca gctcaaggca atccgccctg acctggagat tctcccactt gcgcggaaac 60 attgacaccg gcatgggcaa ggtcacctcc ggtgaactcg atg ctt gtg atg ctc 115 Met Leu Val Met Leu 1 5 gcc tac gca ggc ctc acc cgc gtc ggc atg cag gac cgc gca acg gaa 163 Ala Tyr Ala Gly Leu Thr Arg Val Gly Met Gln Asp Arg Ala Thr Glu 10 15 20 gtt ttc gac gcc gac atc atc atg ccc gcc ccc gca cag ggc gca ctt 211 Val Phe Asp Ala Asp Ile Ile Met Pro Ala Pro Ala Gln Gly Ala Leu 25 30 35 gcg atc gaa tgc cgc gcc gac gac act gaa acc gtc cgc gcg ctc aac 259 Ala Ile Glu Cys Arg Ala Asp Asp Thr Glu Thr Val Arg Ala Leu Asn 40 45 50 atg ctg atg cac gcc gac acg ttt gtt tcc gcg gtt gca gaa cgc acc 307 Met Leu Met His Ala Asp Thr Phe Val Ser Ala Val Ala Glu Arg Thr 55 60 65 gtg ctc aac cgc ctc gaa gct ggc tgt acc gcg cct gtc gca gcg cac 355 Val Leu Asn Arg Leu Glu Ala Gly Cys Thr Ala Pro Val Ala Ala His 70 75 80 85 gcc acc ttg gac ggc tac tcc ggc gac acc atg act ctc acc gcc ggc 403 Ala Thr Leu Asp Gly Tyr Ser Gly Asp Thr Met Thr Leu Thr Ala Gly 90 95 100 gtc tac gca ctt gac ggc tct gac cag ctg gta ttc tcc gcc gaa ggt 451 Val Tyr Ala Leu Asp Gly Ser Asp Gln Leu Val Phe Ser Ala Glu Gly 105 110 115 gac ggc gcc cgc cca gaa gag ctc ggc gag ctc gtt gca caa cag ctt 499 Asp Gly Ala Arg Pro Glu Glu Leu Gly Glu Leu Val Ala Gln Gln Leu 120 125 130 atc gac gcc gga gcc gcc aat ttg ctc ggc gac cgc agc taattagggc 548 Ile Asp Ala Gly Ala Ala Asn Leu Leu Gly Asp Arg Ser 135 140 145 ccgaaatttc cat 561 <210> 812 <211> 146 <212> PRT <213> Corynebacterium glutamicum <400> 812 Met Leu Val Met Leu Ala Tyr Ala Gly Leu Thr Arg Val Gly Met Gln 1 5 10 15 Asp Arg Ala Thr Glu Val Phe Asp Ala Asp Ile Ile Met Pro Ala Pro 20 25 30 Ala Gln Gly Ala Leu Ala Ile Glu Cys Arg Ala Asp Asp Thr Glu Thr 35 40 45 Val Arg Ala Leu Asn Met Leu Met His Ala Asp Thr Phe Val Ser Ala 50 55 60 Val Ala Glu Arg Thr Val Leu Asn Arg Leu Glu Ala Gly Cys Thr Ala 65 70 75 80 Pro Val Ala Ala His Ala Thr Leu Asp Gly Tyr Ser Gly Asp Thr Met 85 90 95 Thr Leu Thr Ala Gly Val Tyr Ala Leu Asp Gly Ser Asp Gln Leu Val 100 105 110 Phe Ser Ala Glu Gly Asp Gly Ala Arg Pro Glu Glu Leu Gly Glu Leu 115 120 125 Val Ala Gln Gln Leu Ile Asp Ala Gly Ala Ala Asn Leu Leu Gly Asp 130 135 140 Arg Ser 145 <210> 813 <211> 1449 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1426) <223> RXN01162 <400> 813 catcgaatac gtgccctgct gaatagatga catcgcagag atctataaga gtcagtggtt 60 gtcggggttt cacagtcact tattctatgc aggattcacc atg tat atc gtg ggg 115 Met Tyr Ile Val Gly 1 5 att tgt cta caa tta gtg gtt atg agc caa ccg atg tca gca ccc gac 163 Ile Cys Leu Gln Leu Val Val Met Ser Gln Pro Met Ser Ala Pro Asp 10 15 20 tcc gct cca gga aca gag cgc ggt cat gaa cgc acc cat ttt gcg gta 211 Ser Ala Pro Gly Thr Glu Arg Gly His Glu Arg Thr His Phe Ala Val 25 30 35 gtc ggt gac tcc cag gat cca gca cag gca aca gct cct aga gcg cca 259 Val Gly Asp Ser Gln Asp Pro Ala Gln Ala Thr Ala Pro Arg Ala Pro 40 45 50 gca gaa tca att act ttg att ggt att ggt acc gat ggg ttt gag ggg 307 Ala Glu Ser Ile Thr Leu Ile Gly Ile Gly Thr Asp Gly Phe Glu Gly 55 60 65 ctc gga ctc aag gca cag caa gca tta caa cgt gcc tct gtg gtg att 355 Leu Gly Leu Lys Ala Gln Gln Ala Leu Gln Arg Ala Ser Val Val Ile 70 75 80 85 gga tca tgg cgc cag ctc aat ctc gta cct gat gcc att aag gca gag 403 Gly Ser Trp Arg Gln Leu Asn Leu Val Pro Asp Ala Ile Lys Ala Glu 90 95 100 cgt cgc cca tgg ccg ggt aat acc aag cat cct gat tta gat gcc ttg 451 Arg Arg Pro Trp Pro Gly Asn Thr Lys His Pro Asp Leu Asp Ala Leu 105 110 115 ttt aaa gag ttc ctc ggt cgg cat gtt gct gtt ctg gcc tct ggc gat 499 Phe Lys Glu Phe Leu Gly Arg His Val Ala Val Leu Ala Ser Gly Asp 120 125 130 cca ctg ttt tac ggc gtg ggc acc gca atg gtc cat gtg ctg ggg atg 547 Pro Leu Phe Tyr Gly Val Gly Thr Ala Met Val His Val Leu Gly Met 135 140 145 gat aga ctc acg gtt att ccg gga cca tca tcc gcg tcg ctt gct tgc 595 Asp Arg Leu Thr Val Ile Pro Gly Pro Ser Ser Ala Ser Leu Ala Cys 150 155 160 165 gcc cgc ttg ggt tgg aca gtc aac cgc aca cgg gtg gtg tac cta gga 643 Ala Arg Leu Gly Trp Thr Val Asn Arg Thr Arg Val Val Tyr Leu Gly 170 175 180 caa gaa ccc att gag aca ctc atc ccg att att gaa tca ggc gct caa 691 Gln Glu Pro Ile Glu Thr Leu Ile Pro Ile Ile Glu Ser Gly Ala Gln 185 190 195 ttc ctc gtc ttg ggt aaa gat gaa ttc agt aca gct caa gtt gcc acg 739 Phe Leu Val Leu Gly Lys Asp Glu Phe Ser Thr Ala Gln Val Ala Thr 200 205 210 ttg ttg aat gaa ctc gga ctg ggg gag act cca ctg act gtg ctc agc 787 Leu Leu Asn Glu Leu Gly Leu Gly Glu Thr Pro Leu Thr Val Leu Ser 215 220 225 gat ttg ggc agt act gat gag gag atc acc caa ggc aca gct tca cat 835 Asp Leu Gly Ser Thr Asp Glu Glu Ile Thr Gln Gly Thr Ala Ser His 230 235 240 245 cca cca gct gca gtg tct gtt ctc aac gtg att gct gtg gga gct cgc 883 Pro Pro Ala Ala Val Ser Val Leu Asn Val Ile Ala Val Gly Ala Arg 250 255 260 acc gca atg ccg aaa ccc cac ttt gaa ggc gac gta tca aac gaa gac 931 Thr Ala Met Pro Lys Pro His Phe Glu Gly Asp Val Ser Asn Glu Asp 265 270 275 ctt cgg gca ctg acc gtg gca gct cta gaa ccc acc cag gga caa atg 979 Leu Arg Ala Leu Thr Val Ala Ala Leu Glu Pro Thr Gln Gly Gln Met 280 285 290 ctg tgg acc ttc ggg gat att gga gca gca ctt gcc tgc gat tgg cta 1027 Leu Trp Thr Phe Gly Asp Ile Gly Ala Ala Leu Ala Cys Asp Trp Leu 295 300 305 cgc gca gcc ggc aac aag gcg cac gcc att agt ttt gcc tcc atg gtt 1075 Arg Ala Ala Gly Asn Lys Ala His Ala Ile Ser Phe Ala Ser Met Val 310 315 320 325 gag caa agc caa agg aat gct cgc aaa cta ggt gta tcc acc ctc agt 1123 Glu Gln Ser Gln Arg Asn Ala Arg Lys Leu Gly Val Ser Thr Leu Ser 330 335 340 gtg aaa gag acc ctg tca ccc aaa acg ctc aaa gat atc cgc tat gta 1171 Val Lys Glu Thr Leu Ser Pro Lys Thr Leu Lys Asp Ile Arg Tyr Val 345 350 355 caa gga cca gaa tca gca agc cca cat gcc atc ttc atg aac aaa ggc 1219 Gln Gly Pro Glu Ser Ala Ser Pro His Ala Ile Phe Met Asn Lys Gly 360 365 370 cta ggc atc gat cta gtt cct gaa acc gca tgg atg atg ctg cgg cct 1267 Leu Gly Ile Asp Leu Val Pro Glu Thr Ala Trp Met Met Leu Arg Pro 375 380 385 gga gga aag ctc att gcg caa gcc tcc aca gaa gac aac atc gca aag 1315 Gly Gly Lys Leu Ile Ala Gln Ala Ser Thr Glu Asp Asn Ile Ala Lys 390 395 400 405 ctt cac aca ctc caa gaa caa cac ggc gga atc atc aaa cac atc cgc 1363 Leu His Thr Leu Gln Glu Gln His Gly Gly Ile Ile Lys His Ile Arg 410 415 420 atc gac gac aca gac gtg cac caa tgg cga gtt aca aag ccg gtg act 1411 Ile Asp Asp Thr Asp Val His Gln Trp Arg Val Thr Lys Pro Val Thr 425 430 435 cca gaa gcg gtg aat tagcatcaaa aaccaacccc atg 1449 Pro Glu Ala Val Asn 440 <210> 814 <211> 442 <212> PRT <213> Corynebacterium glutamicum <400> 814 Met Tyr Ile Val Gly Ile Cys Leu Gln Leu Val Val Met Ser Gln Pro 1 5 10 15 Met Ser Ala Pro Asp Ser Ala Pro Gly Thr Glu Arg Gly His Glu Arg 20 25 30 Thr His Phe Ala Val Val Gly Asp Ser Gln Asp Pro Ala Gln Ala Thr 35 40 45 Ala Pro Arg Ala Pro Ala Glu Ser Ile Thr Leu Ile Gly Ile Gly Thr 50 55 60 Asp Gly Phe Glu Gly Leu Gly Leu Lys Ala Gln Gln Ala Leu Gln Arg 65 70 75 80 Ala Ser Val Val Ile Gly Ser Trp Arg Gln Leu Asn Leu Val Pro Asp 85 90 95 Ala Ile Lys Ala Glu Arg Arg Pro Trp Pro Gly Asn Thr Lys His Pro 100 105 110 Asp Leu Asp Ala Leu Phe Lys Glu Phe Leu Gly Arg His Val Ala Val 115 120 125 Leu Ala Ser Gly Asp Pro Leu Phe Tyr Gly Val Gly Thr Ala Met Val 130 135 140 His Val Leu Gly Met Asp Arg Leu Thr Val Ile Pro Gly Pro Ser Ser 145 150 155 160 Ala Ser Leu Ala Cys Ala Arg Leu Gly Trp Thr Val Asn Arg Thr Arg 165 170 175 Val Val Tyr Leu Gly Gln Glu Pro Ile Glu Thr Leu Ile Pro Ile Ile 180 185 190 Glu Ser Gly Ala Gln Phe Leu Val Leu Gly Lys Asp Glu Phe Ser Thr 195 200 205 Ala Gln Val Ala Thr Leu Leu Asn Glu Leu Gly Leu Gly Glu Thr Pro 210 215 220 Leu Thr Val Leu Ser Asp Leu Gly Ser Thr Asp Glu Glu Ile Thr Gln 225 230 235 240 Gly Thr Ala Ser His Pro Pro Ala Ala Val Ser Val Leu Asn Val Ile 245 250 255 Ala Val Gly Ala Arg Thr Ala Met Pro Lys Pro His Phe Glu Gly Asp 260 265 270 Val Ser Asn Glu Asp Leu Arg Ala Leu Thr Val Ala Ala Leu Glu Pro 275 280 285 Thr Gln Gly Gln Met Leu Trp Thr Phe Gly Asp Ile Gly Ala Ala Leu 290 295 300 Ala Cys Asp Trp Leu Arg Ala Ala Gly Asn Lys Ala His Ala Ile Ser 305 310 315 320 Phe Ala Ser Met Val Glu Gln Ser Gln Arg Asn Ala Arg Lys Leu Gly 325 330 335 Val Ser Thr Leu Ser Val Lys Glu Thr Leu Ser Pro Lys Thr Leu Lys 340 345 350 Asp Ile Arg Tyr Val Gln Gly Pro Glu Ser Ala Ser Pro His Ala Ile 355 360 365 Phe Met Asn Lys Gly Leu Gly Ile Asp Leu Val Pro Glu Thr Ala Trp 370 375 380 Met Met Leu Arg Pro Gly Gly Lys Leu Ile Ala Gln Ala Ser Thr Glu 385 390 395 400 Asp Asn Ile Ala Lys Leu His Thr Leu Gln Glu Gln His Gly Gly Ile 405 410 415 Ile Lys His Ile Arg Ile Asp Asp Thr Asp Val His Gln Trp Arg Val 420 425 430 Thr Lys Pro Val Thr Pro Glu Ala Val Asn 435 440 <210> 815 <211> 1345 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1345) <223> FRXA01162 <400> 815 catcgaatac gtgccctgct gaatagatga catcgcagag atctataaga gtcagtggtt 60 gtcggggttt cacagtcact tattctatgc aggattcacc atg tat atc gtg ggg 115 Met Tyr Ile Val Gly 1 5 att tgt cta caa tta gtg gtt atg agc caa ccg atg tca gca ccc gac 163 Ile Cys Leu Gln Leu Val Val Met Ser Gln Pro Met Ser Ala Pro Asp 10 15 20 tcc gct cca gga aca gag cgc ggt cat gaa cgc acc cat ttt gcg gta 211 Ser Ala Pro Gly Thr Glu Arg Gly His Glu Arg Thr His Phe Ala Val 25 30 35 gtc ggt gac tcc cag gat cca gca cag gca aca gct cct aga gcg cca 259 Val Gly Asp Ser Gln Asp Pro Ala Gln Ala Thr Ala Pro Arg Ala Pro 40 45 50 gca gaa tca att act ttg att ggt att ggt acc gat ggg ttt gag ggg 307 Ala Glu Ser Ile Thr Leu Ile Gly Ile Gly Thr Asp Gly Phe Glu Gly 55 60 65 ctc gga ctc aag gca cag caa gca tta caa cgt gcc tct gtg gtg att 355 Leu Gly Leu Lys Ala Gln Gln Ala Leu Gln Arg Ala Ser Val Val Ile 70 75 80 85 gga tca tgg cgc cag ctc aat ctc gta cct gat gcc att aag gca gag 403 Gly Ser Trp Arg Gln Leu Asn Leu Val Pro Asp Ala Ile Lys Ala Glu 90 95 100 cgt cgc cca tgg ccg ggt aat acc aag cat cct gat tta gat gcc ttg 451 Arg Arg Pro Trp Pro Gly Asn Thr Lys His Pro Asp Leu Asp Ala Leu 105 110 115 ttt aaa gag ttc ctc ggt cgg cat gtt gct gtt ctg gcc tct ggc gat 499 Phe Lys Glu Phe Leu Gly Arg His Val Ala Val Leu Ala Ser Gly Asp 120 125 130 cca ctg ttt tac ggc gtg ggc acc gca atg gtc cat gtg ctg ggg atg 547 Pro Leu Phe Tyr Gly Val Gly Thr Ala Met Val His Val Leu Gly Met 135 140 145 gat aga ctc acg gtt att ccg gga cca tca tcc gcg tcg ctt gct tgc 595 Asp Arg Leu Thr Val Ile Pro Gly Pro Ser Ser Ala Ser Leu Ala Cys 150 155 160 165 gcc cgc ttg ggt tgg aca gtc aac cgc aca cgg gtg gtg tac cta gga 643 Ala Arg Leu Gly Trp Thr Val Asn Arg Thr Arg Val Val Tyr Leu Gly 170 175 180 caa gaa ccc att gag aca ctc atc ccg att att gaa tca ggc gct caa 691 Gln Glu Pro Ile Glu Thr Leu Ile Pro Ile Ile Glu Ser Gly Ala Gln 185 190 195 ttc ctc gtc ttg ggt aaa gat gaa ttc agt aca gct caa gtt gcc acg 739 Phe Leu Val Leu Gly Lys Asp Glu Phe Ser Thr Ala Gln Val Ala Thr 200 205 210 ttg ttg aat gaa ctc gga ctg ggg gag act cca ctg act gtg ctc agc 787 Leu Leu Asn Glu Leu Gly Leu Gly Glu Thr Pro Leu Thr Val Leu Ser 215 220 225 gat ttg ggc agt act gat gag gag atc acc caa ggc aca gct tca cat 835 Asp Leu Gly Ser Thr Asp Glu Glu Ile Thr Gln Gly Thr Ala Ser His 230 235 240 245 cca cca gct gca gtg tct gtt ctc aac gtg att gct gtg gga gct cgc 883 Pro Pro Ala Ala Val Ser Val Leu Asn Val Ile Ala Val Gly Ala Arg 250 255 260 acc gca atg ccg aaa ccc cac ttt gaa ggc gac gta tca aac gaa gac 931 Thr Ala Met Pro Lys Pro His Phe Glu Gly Asp Val Ser Asn Glu Asp 265 270 275 ctt cgg gca ctg acc gtg gca gct cta gaa ccc acc cag gga caa atg 979 Leu Arg Ala Leu Thr Val Ala Ala Leu Glu Pro Thr Gln Gly Gln Met 280 285 290 ctg tgg acc ttc ggg gat att gga gca gca ctt gcc tgc gat tgg cta 1027 Leu Trp Thr Phe Gly Asp Ile Gly Ala Ala Leu Ala Cys Asp Trp Leu 295 300 305 cgc gca gcc ggc aac aag gcg cac gcc att agt ttt gcc tcc atg gtt 1075 Arg Ala Ala Gly Asn Lys Ala His Ala Ile Ser Phe Ala Ser Met Val 310 315 320 325 gag caa agc caa agg aat gct cgc aaa cta ggt gta tcc acc ctc agt 1123 Glu Gln Ser Gln Arg Asn Ala Arg Lys Leu Gly Val Ser Thr Leu Ser 330 335 340 gtg aaa gag acc ctg tca ccc aaa acg ctc aaa gat atc cgc tat gta 1171 Val Lys Glu Thr Leu Ser Pro Lys Thr Leu Lys Asp Ile Arg Tyr Val 345 350 355 caa gga cca gaa tca gca agc cca cat gcc atc ttc atg aac aaa ggc 1219 Gln Gly Pro Glu Ser Ala Ser Pro His Ala Ile Phe Met Asn Lys Gly 360 365 370 cta ggc atc gat cta gtt cct gaa acc gca tgg atg atg ctg cgg cct 1267 Leu Gly Ile Asp Leu Val Pro Glu Thr Ala Trp Met Met Leu Arg Pro 375 380 385 gga gga aag ctc att gcg caa gcc tcc aca gaa gac aac atc gca aag 1315 Gly Gly Lys Leu Ile Ala Gln Ala Ser Thr Glu Asp Asn Ile Ala Lys 390 395 400 405 ctt cac aca ctc caa gaa caa cac ggc gga 1345 Leu His Thr Leu Gln Glu Gln His Gly Gly 410 415 <210> 816 <211> 415 <212> PRT <213> Corynebacterium glutamicum <400> 816 Met Tyr Ile Val Gly Ile Cys Leu Gln Leu Val Val Met Ser Gln Pro 1 5 10 15 Met Ser Ala Pro Asp Ser Ala Pro Gly Thr Glu Arg Gly His Glu Arg 20 25 30 Thr His Phe Ala Val Val Gly Asp Ser Gln Asp Pro Ala Gln Ala Thr 35 40 45 Ala Pro Arg Ala Pro Ala Glu Ser Ile Thr Leu Ile Gly Ile Gly Thr 50 55 60 Asp Gly Phe Glu Gly Leu Gly Leu Lys Ala Gln Gln Ala Leu Gln Arg 65 70 75 80 Ala Ser Val Val Ile Gly Ser Trp Arg Gln Leu Asn Leu Val Pro Asp 85 90 95 Ala Ile Lys Ala Glu Arg Arg Pro Trp Pro Gly Asn Thr Lys His Pro 100 105 110 Asp Leu Asp Ala Leu Phe Lys Glu Phe Leu Gly Arg His Val Ala Val 115 120 125 Leu Ala Ser Gly Asp Pro Leu Phe Tyr Gly Val Gly Thr Ala Met Val 130 135 140 His Val Leu Gly Met Asp Arg Leu Thr Val Ile Pro Gly Pro Ser Ser 145 150 155 160 Ala Ser Leu Ala Cys Ala Arg Leu Gly Trp Thr Val Asn Arg Thr Arg 165 170 175 Val Val Tyr Leu Gly Gln Glu Pro Ile Glu Thr Leu Ile Pro Ile Ile 180 185 190 Glu Ser Gly Ala Gln Phe Leu Val Leu Gly Lys Asp Glu Phe Ser Thr 195 200 205 Ala Gln Val Ala Thr Leu Leu Asn Glu Leu Gly Leu Gly Glu Thr Pro 210 215 220 Leu Thr Val Leu Ser Asp Leu Gly Ser Thr Asp Glu Glu Ile Thr Gln 225 230 235 240 Gly Thr Ala Ser His Pro Pro Ala Ala Val Ser Val Leu Asn Val Ile 245 250 255 Ala Val Gly Ala Arg Thr Ala Met Pro Lys Pro His Phe Glu Gly Asp 260 265 270 Val Ser Asn Glu Asp Leu Arg Ala Leu Thr Val Ala Ala Leu Glu Pro 275 280 285 Thr Gln Gly Gln Met Leu Trp Thr Phe Gly Asp Ile Gly Ala Ala Leu 290 295 300 Ala Cys Asp Trp Leu Arg Ala Ala Gly Asn Lys Ala His Ala Ile Ser 305 310 315 320 Phe Ala Ser Met Val Glu Gln Ser Gln Arg Asn Ala Arg Lys Leu Gly 325 330 335 Val Ser Thr Leu Ser Val Lys Glu Thr Leu Ser Pro Lys Thr Leu Lys 340 345 350 Asp Ile Arg Tyr Val Gln Gly Pro Glu Ser Ala Ser Pro His Ala Ile 355 360 365 Phe Met Asn Lys Gly Leu Gly Ile Asp Leu Val Pro Glu Thr Ala Trp 370 375 380 Met Met Leu Arg Pro Gly Gly Lys Leu Ile Ala Gln Ala Ser Thr Glu 385 390 395 400 Asp Asn Ile Ala Lys Leu His Thr Leu Gln Glu Gln His Gly Gly 405 410 415 <210> 817 <211> 873 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(850) <223> RXA01692 <400> 817 gggctgatgc gaagtcagct tcgagtttga aaggtgcagt attcatggtt caagcctagt 60 gttcgggttc tggcaattgt tgggactagg attaatgccc atg acg att tcc caa 115 Met Thr Ile Ser Gln 1 5 gaa aac cag cca ata atc cag cca gtc tcc tta att ggt gga ggt cct 163 Glu Asn Gln Pro Ile Ile Gln Pro Val Ser Leu Ile Gly Gly Gly Pro 10 15 20 ggt gca tgg gac tta att acg gtg cgt ggg atg aat cgc ctt cag gag 211 Gly Ala Trp Asp Leu Ile Thr Val Arg Gly Met Asn Arg Leu Gln Glu 25 30 35 gct gat gtc att ttg gct gat cac ttg ggg ccc act gat gag ttg gaa 259 Ala Asp Val Ile Leu Ala Asp His Leu Gly Pro Thr Asp Glu Leu Glu 40 45 50 aaa ttg tgc gac atc agc tcg aag act gtt gtt gat gtg tcc aag ctt 307 Lys Leu Cys Asp Ile Ser Ser Lys Thr Val Val Asp Val Ser Lys Leu 55 60 65 ccg tat ggg cgg cag gtc act cag gag cgt act aat gag atg ctt gtt 355 Pro Tyr Gly Arg Gln Val Thr Gln Glu Arg Thr Asn Glu Met Leu Val 70 75 80 85 gaa tac gca cag cag gga cta aag gtg gtt cgc ctt aaa ggt ggt gac 403 Glu Tyr Ala Gln Gln Gly Leu Lys Val Val Arg Leu Lys Gly Gly Asp 90 95 100 cct tat gtc ttc ggt cgg ggt ttt gaa gag ttg gag ttt ttg ggc gag 451 Pro Tyr Val Phe Gly Arg Gly Phe Glu Glu Leu Glu Phe Leu Gly Glu 105 110 115 cat gga att gaa tgc gag gtc att ccg ggt gtg acc agt gcg gtg tcc 499 His Gly Ile Glu Cys Glu Val Ile Pro Gly Val Thr Ser Ala Val Ser 120 125 130 gtt cca gcg gcg gca ggt att cct att act aat cgg gga gtg gtg cat 547 Val Pro Ala Ala Ala Gly Ile Pro Ile Thr Asn Arg Gly Val Val His 135 140 145 tcc ttt acc gtg gtg tct gga cat ttg cct cca ggc cat ccg aag tca 595 Ser Phe Thr Val Val Ser Gly His Leu Pro Pro Gly His Pro Lys Ser 150 155 160 165 ctg gtt gat tgg gct gcg ttg gcc aaa tcg ggt ggc acc ttg tcc atc 643 Leu Val Asp Trp Ala Ala Leu Ala Lys Ser Gly Gly Thr Leu Ser Ile 170 175 180 atc atg ggt gtg aaa aat gcg ggt gcg att gcc cag gcg ctc atg gac 691 Ile Met Gly Val Lys Asn Ala Gly Ala Ile Ala Gln Ala Leu Met Asp 185 190 195 ggc ggg ctt gat gca gat act cca gca gct gtt att cag gaa ggc act 739 Gly Gly Leu Asp Ala Asp Thr Pro Ala Ala Val Ile Gln Glu Gly Thr 200 205 210 act gat gca caa cgc tca gtt cgg tgc acc ttg ggc aca ttg ggt gca 787 Thr Asp Ala Gln Arg Ser Val Arg Cys Thr Leu Gly Thr Leu Gly Ala 215 220 225 gtc atg gtg gag gaa gag att aag cct cca gct gtg tat gtc att gga 835 Val Met Val Glu Glu Glu Ile Lys Pro Pro Ala Val Tyr Val Ile Gly 230 235 240 245 caa gtt gct ggc ctc taagcagatc gcctaagaat ggg 873 Gln Val Ala Gly Leu 250 <210> 818 <211> 250 <212> PRT <213> Corynebacterium glutamicum <400> 818 Met Thr Ile Ser Gln Glu Asn Gln Pro Ile Ile Gln Pro Val Ser Leu 1 5 10 15 Ile Gly Gly Gly Pro Gly Ala Trp Asp Leu Ile Thr Val Arg Gly Met 20 25 30 Asn Arg Leu Gln Glu Ala Asp Val Ile Leu Ala Asp His Leu Gly Pro 35 40 45 Thr Asp Glu Leu Glu Lys Leu Cys Asp Ile Ser Ser Lys Thr Val Val 50 55 60 Asp Val Ser Lys Leu Pro Tyr Gly Arg Gln Val Thr Gln Glu Arg Thr 65 70 75 80 Asn Glu Met Leu Val Glu Tyr Ala Gln Gln Gly Leu Lys Val Val Arg 85 90 95 Leu Lys Gly Gly Asp Pro Tyr Val Phe Gly Arg Gly Phe Glu Glu Leu 100 105 110 Glu Phe Leu Gly Glu His Gly Ile Glu Cys Glu Val Ile Pro Gly Val 115 120 125 Thr Ser Ala Val Ser Val Pro Ala Ala Ala Gly Ile Pro Ile Thr Asn 130 135 140 Arg Gly Val Val His Ser Phe Thr Val Val Ser Gly His Leu Pro Pro 145 150 155 160 Gly His Pro Lys Ser Leu Val Asp Trp Ala Ala Leu Ala Lys Ser Gly 165 170 175 Gly Thr Leu Ser Ile Ile Met Gly Val Lys Asn Ala Gly Ala Ile Ala 180 185 190 Gln Ala Leu Met Asp Gly Gly Leu Asp Ala Asp Thr Pro Ala Ala Val 195 200 205 Ile Gln Glu Gly Thr Thr Asp Ala Gln Arg Ser Val Arg Cys Thr Leu 210 215 220 Gly Thr Leu Gly Ala Val Met Val Glu Glu Glu Ile Lys Pro Pro Ala 225 230 235 240 Val Tyr Val Ile Gly Gln Val Ala Gly Leu 245 250 <210> 819 <211> 1917 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1894) <223> RXN00371 <400> 819 gtcgtggaca atcccggatc gaaaatttga ttcggctttt ttcatggctg ttgatggagt 60 acgttggtcg ttttcgagac aagtactaga aaagatattg atg act atc gcc cat 115 Met Thr Ile Ala His 1 5 aag ccc gag atg gct gaa act acc ggg atc gag acc aac cag gtt tcc 163 Lys Pro Glu Met Ala Glu Thr Thr Gly Ile Glu Thr Asn Gln Val Ser 10 15 20 gaa acc atc ggg gtt gaa tcg ctc acg cac gga aac tta cgt cct gtt 211 Glu Thr Ile Gly Val Glu Ser Leu Thr His Gly Asn Leu Arg Pro Val 25 30 35 tca tct ttt gag gga cag cat gag gga caa acg gaa gag tta ctt cca 259 Ser Ser Phe Glu Gly Gln His Glu Gly Gln Thr Glu Glu Leu Leu Pro 40 45 50 ggc aaa gtc att ttt gtt ggg gcc ggt ccc ggt aac cct gat ctt ctt 307 Gly Lys Val Ile Phe Val Gly Ala Gly Pro Gly Asn Pro Asp Leu Leu 55 60 65 aca gtt cgt gcc cgt gaa gtt ctg ggc aac gcg gtt cgt gcg att act 355 Thr Val Arg Ala Arg Glu Val Leu Gly Asn Ala Val Arg Ala Ile Thr 70 75 80 85 gat gaa caa gta cta agc ggc gtt cga gct ttt gtc gcc act gaa att 403 Asp Glu Gln Val Leu Ser Gly Val Arg Ala Phe Val Ala Thr Glu Ile 90 95 100 cct gtg ccg gaa gat aag ctt cag gct gcg gaa gat gag tac gag cgc 451 Pro Val Pro Glu Asp Lys Leu Gln Ala Ala Glu Asp Glu Tyr Glu Arg 105 110 115 atc tgc att gaa gcg aag gag aac ggt gca cgc cgt aag cct cct cgt 499 Ile Cys Ile Glu Ala Lys Glu Asn Gly Ala Arg Arg Lys Pro Pro Arg 120 125 130 cca gca cca cca acc gct gca gag atc acg gaa gtt tct gag gcg act 547 Pro Ala Pro Pro Thr Ala Ala Glu Ile Thr Glu Val Ser Glu Ala Thr 135 140 145 cca gct cag att gtt gag ctt gtg cag gat gct ctt tct tat ggt gga 595 Pro Ala Gln Ile Val Glu Leu Val Gln Asp Ala Leu Ser Tyr Gly Gly 150 155 160 165 gat gtt att cgt ctt gtc acc ggc aac cca ttg agc agc gat gcc aca 643 Asp Val Ile Arg Leu Val Thr Gly Asn Pro Leu Ser Ser Asp Ala Thr 170 175 180 ctg gct gag atc tct gca gtt tcc gag gct ggc ctg gag ttc cag gtg 691 Leu Ala Glu Ile Ser Ala Val Ser Glu Ala Gly Leu Glu Phe Gln Val 185 190 195 gtt cca ggt atg tct ttg cct gca acg gtt cct gca ttt gcg gga att 739 Val Pro Gly Met Ser Leu Pro Ala Thr Val Pro Ala Phe Ala Gly Ile 200 205 210 gcg ttg ggt tct acc tac acc gaa act gat gtc aac ggt caa aac ttg 787 Ala Leu Gly Ser Thr Tyr Thr Glu Thr Asp Val Asn Gly Gln Asn Leu 215 220 225 gac tgg gat cag ttg gct agc gca cct cag cct ttg gtg ctg cag gcc 835 Asp Trp Asp Gln Leu Ala Ser Ala Pro Gln Pro Leu Val Leu Gln Ala 230 235 240 245 cgc gtg gat gac ctt tcc cgt att gca cag gaa cta aag gcc cgc aat 883 Arg Val Asp Asp Leu Ser Arg Ile Ala Gln Glu Leu Lys Ala Arg Asn 250 255 260 atg tct ttg gaa act cct gtt tct gtc acc gct aac ggc acc acc cgt 931 Met Ser Leu Glu Thr Pro Val Ser Val Thr Ala Asn Gly Thr Thr Arg 265 270 275 ttg cag cgc acc tat gac acc act tta ggt ctg ttg cac aag ctt gat 979 Leu Gln Arg Thr Tyr Asp Thr Thr Leu Gly Leu Leu His Lys Leu Asp 280 285 290 gct gaa cta agc gga cct ttg gtt gtt acc ttg ggc aag ggt gtg gat 1027 Ala Glu Leu Ser Gly Pro Leu Val Val Thr Leu Gly Lys Gly Val Asp 295 300 305 gat cgc tcc aag tac tct tgg tgg gaa aac cgc gct ctg tac ggt tgg 1075 Asp Arg Ser Lys Tyr Ser Trp Trp Glu Asn Arg Ala Leu Tyr Gly Trp 310 315 320 325 cgt gtg ctg gtg cct cgc gct cgg gag caa gcg gca tcc atg tcc gca 1123 Arg Val Leu Val Pro Arg Ala Arg Glu Gln Ala Ala Ser Met Ser Ala 330 335 340 cgt ctg agc agc cac ggc gct atc ccg cag gaa gtc cct acc att tct 1171 Arg Leu Ser Ser His Gly Ala Ile Pro Gln Glu Val Pro Thr Ile Ser 345 350 355 gtc gaa cca ccg cgc aac cca gcg caa atg gaa cgc gcc atc aag ggc 1219 Val Glu Pro Pro Arg Asn Pro Ala Gln Met Glu Arg Ala Ile Lys Gly 360 365 370 atc gtc gaa gga cgc tac cag tgg gtt gtc ctc acc agc gtc aac gca 1267 Ile Val Glu Gly Arg Tyr Gln Trp Val Val Leu Thr Ser Val Asn Ala 375 380 385 gtg aag gca gtc tgg gag aaa atc acc gaa ttc ggc ctc gat tca cgt 1315 Val Lys Ala Val Trp Glu Lys Ile Thr Glu Phe Gly Leu Asp Ser Arg 390 395 400 405 tcc ttc gcg ggc gtc cgc atc gcc gca gtc ggt gaa aaa acc gcc gct 1363 Ser Phe Ala Gly Val Arg Ile Ala Ala Val Gly Glu Lys Thr Ala Ala 410 415 420 gag atc cgc gcg ctc ggc atc acg ccg gag ctt ctg cct gca cgt acc 1411 Glu Ile Arg Ala Leu Gly Ile Thr Pro Glu Leu Leu Pro Ala Arg Thr 425 430 435 agg caa aat gcg caa ggg ctt gtc gac gtg ttc ccc gaa tat ttc gaa 1459 Arg Gln Asn Ala Gln Gly Leu Val Asp Val Phe Pro Glu Tyr Phe Glu 440 445 450 gaa ctc gat cca gtc ggc cgt gtc ctc ttg ccg cgc gca gat atc gca 1507 Glu Leu Asp Pro Val Gly Arg Val Leu Leu Pro Arg Ala Asp Ile Ala 455 460 465 acc gac gtg ctt gtc gac ggc ctg acc cac ctt ggt tgg gaa gtc gaa 1555 Thr Asp Val Leu Val Asp Gly Leu Thr His Leu Gly Trp Glu Val Glu 470 475 480 485 gac gtg gtg gct tac cgc acc gtc cgc gca gca cca cca agc gct gat 1603 Asp Val Val Ala Tyr Arg Thr Val Arg Ala Ala Pro Pro Ser Ala Asp 490 495 500 atc cga gat atg atc aag acc ggc gga ttt gat gca gtt gcc ttc acc 1651 Ile Arg Asp Met Ile Lys Thr Gly Gly Phe Asp Ala Val Ala Phe Thr 505 510 515 tct tcg tcg acc gtg aag aac ctc gtt ggt atc gcg ggt aaa cca cac 1699 Ser Ser Ser Thr Val Lys Asn Leu Val Gly Ile Ala Gly Lys Pro His 520 525 530 cca cgc acc atc gtc gcg tgc atc gga ccc atg act gca gcg acc gct 1747 Pro Arg Thr Ile Val Ala Cys Ile Gly Pro Met Thr Ala Ala Thr Ala 535 540 545 gaa gaa ctg gga ctg cgc gtt gat gtc atg cca gag atc gcc gaa gta 1795 Glu Glu Leu Gly Leu Arg Val Asp Val Met Pro Glu Ile Ala Glu Val 550 555 560 565 cca gaa ctg atc gac gct ctt gcg gaa cac gtg gcg gat ctg cgc gct 1843 Pro Glu Leu Ile Asp Ala Leu Ala Glu His Val Ala Asp Leu Arg Ala 570 575 580 aag ggc gag ctg ccg ccg ccg agg aag aaa cgc agg cgt cga aaa gcg 1891 Lys Gly Glu Leu Pro Pro Pro Arg Lys Lys Arg Arg Arg Arg Lys Ala 585 590 595 tct taaaaggttt ttcactaggg tgt 1917 Ser <210> 820 <211> 598 <212> PRT <213> Corynebacterium glutamicum <400> 820 Met Thr Ile Ala His Lys Pro Glu Met Ala Glu Thr Thr Gly Ile Glu 1 5 10 15 Thr Asn Gln Val Ser Glu Thr Ile Gly Val Glu Ser Leu Thr His Gly 20 25 30 Asn Leu Arg Pro Val Ser Ser Phe Glu Gly Gln His Glu Gly Gln Thr 35 40 45 Glu Glu Leu Leu Pro Gly Lys Val Ile Phe Val Gly Ala Gly Pro Gly 50 55 60 Asn Pro Asp Leu Leu Thr Val Arg Ala Arg Glu Val Leu Gly Asn Ala 65 70 75 80 Val Arg Ala Ile Thr Asp Glu Gln Val Leu Ser Gly Val Arg Ala Phe 85 90 95 Val Ala Thr Glu Ile Pro Val Pro Glu Asp Lys Leu Gln Ala Ala Glu 100 105 110 Asp Glu Tyr Glu Arg Ile Cys Ile Glu Ala Lys Glu Asn Gly Ala Arg 115 120 125 Arg Lys Pro Pro Arg Pro Ala Pro Pro Thr Ala Ala Glu Ile Thr Glu 130 135 140 Val Ser Glu Ala Thr Pro Ala Gln Ile Val Glu Leu Val Gln Asp Ala 145 150 155 160 Leu Ser Tyr Gly Gly Asp Val Ile Arg Leu Val Thr Gly Asn Pro Leu 165 170 175 Ser Ser Asp Ala Thr Leu Ala Glu Ile Ser Ala Val Ser Glu Ala Gly 180 185 190 Leu Glu Phe Gln Val Val Pro Gly Met Ser Leu Pro Ala Thr Val Pro 195 200 205 Ala Phe Ala Gly Ile Ala Leu Gly Ser Thr Tyr Thr Glu Thr Asp Val 210 215 220 Asn Gly Gln Asn Leu Asp Trp Asp Gln Leu Ala Ser Ala Pro Gln Pro 225 230 235 240 Leu Val Leu Gln Ala Arg Val Asp Asp Leu Ser Arg Ile Ala Gln Glu 245 250 255 Leu Lys Ala Arg Asn Met Ser Leu Glu Thr Pro Val Ser Val Thr Ala 260 265 270 Asn Gly Thr Thr Arg Leu Gln Arg Thr Tyr Asp Thr Thr Leu Gly Leu 275 280 285 Leu His Lys Leu Asp Ala Glu Leu Ser Gly Pro Leu Val Val Thr Leu 290 295 300 Gly Lys Gly Val Asp Asp Arg Ser Lys Tyr Ser Trp Trp Glu Asn Arg 305 310 315 320 Ala Leu Tyr Gly Trp Arg Val Leu Val Pro Arg Ala Arg Glu Gln Ala 325 330 335 Ala Ser Met Ser Ala Arg Leu Ser Ser His Gly Ala Ile Pro Gln Glu 340 345 350 Val Pro Thr Ile Ser Val Glu Pro Pro Arg Asn Pro Ala Gln Met Glu 355 360 365 Arg Ala Ile Lys Gly Ile Val Glu Gly Arg Tyr Gln Trp Val Val Leu 370 375 380 Thr Ser Val Asn Ala Val Lys Ala Val Trp Glu Lys Ile Thr Glu Phe 385 390 395 400 Gly Leu Asp Ser Arg Ser Phe Ala Gly Val Arg Ile Ala Ala Val Gly 405 410 415 Glu Lys Thr Ala Ala Glu Ile Arg Ala Leu Gly Ile Thr Pro Glu Leu 420 425 430 Leu Pro Ala Arg Thr Arg Gln Asn Ala Gln Gly Leu Val Asp Val Phe 435 440 445 Pro Glu Tyr Phe Glu Glu Leu Asp Pro Val Gly Arg Val Leu Leu Pro 450 455 460 Arg Ala Asp Ile Ala Thr Asp Val Leu Val Asp Gly Leu Thr His Leu 465 470 475 480 Gly Trp Glu Val Glu Asp Val Val Ala Tyr Arg Thr Val Arg Ala Ala 485 490 495 Pro Pro Ser Ala Asp Ile Arg Asp Met Ile Lys Thr Gly Gly Phe Asp 500 505 510 Ala Val Ala Phe Thr Ser Ser Ser Thr Val Lys Asn Leu Val Gly Ile 515 520 525 Ala Gly Lys Pro His Pro Arg Thr Ile Val Ala Cys Ile Gly Pro Met 530 535 540 Thr Ala Ala Thr Ala Glu Glu Leu Gly Leu Arg Val Asp Val Met Pro 545 550 555 560 Glu Ile Ala Glu Val Pro Glu Leu Ile Asp Ala Leu Ala Glu His Val 565 570 575 Ala Asp Leu Arg Ala Lys Gly Glu Leu Pro Pro Pro Arg Lys Lys Arg 580 585 590 Arg Arg Arg Lys Ala Ser 595 <210> 821 <211> 1024 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1024) <223> FRXA00371 <400> 821 gtcgtggaca atcccggatc gaaaatttga ttcggctttt ttcatggctg ttgatggagt 60 acgttggtcg ttttcgagac aagtactaga aaagatattg atg act atc gcc cat 115 Met Thr Ile Ala His 1 5 aag ccc gag atg gct gaa act acc ggg atc gag acc aac cag gtt tcc 163 Lys Pro Glu Met Ala Glu Thr Thr Gly Ile Glu Thr Asn Gln Val Ser 10 15 20 gaa acc atc ggg gtt gaa tcg ctc acg cac gga aac tta cgt cct gtt 211 Glu Thr Ile Gly Val Glu Ser Leu Thr His Gly Asn Leu Arg Pro Val 25 30 35 tca tct ttt gag gga cag cat gag gga caa acg gaa gag tta ctt cca 259 Ser Ser Phe Glu Gly Gln His Glu Gly Gln Thr Glu Glu Leu Leu Pro 40 45 50 ggc aaa gtc att ttt gtt ggg gcc ggt ccc ggt aac cct gat ctt ctt 307 Gly Lys Val Ile Phe Val Gly Ala Gly Pro Gly Asn Pro Asp Leu Leu 55 60 65 aca gtt cgt gcc cgt gaa gtt ctg ggc aac gcg gtt cgt gcg att act 355 Thr Val Arg Ala Arg Glu Val Leu Gly Asn Ala Val Arg Ala Ile Thr 70 75 80 85 gat gaa caa gta cta agc ggc gtt cga gct ttt gtc gcc act gaa att 403 Asp Glu Gln Val Leu Ser Gly Val Arg Ala Phe Val Ala Thr Glu Ile 90 95 100 cct gtg ccg gaa gat aag ctt cag gct gcg gaa gat gag tac gag cgc 451 Pro Val Pro Glu Asp Lys Leu Gln Ala Ala Glu Asp Glu Tyr Glu Arg 105 110 115 atc tgc att gaa gcg aag gag aac ggt gca cgc cgt aag cct cct cgt 499 Ile Cys Ile Glu Ala Lys Glu Asn Gly Ala Arg Arg Lys Pro Pro Arg 120 125 130 cca gca cca cca acc gct gca gag atc acg gaa gtt tct gag gcg act 547 Pro Ala Pro Pro Thr Ala Ala Glu Ile Thr Glu Val Ser Glu Ala Thr 135 140 145 cca gct cag att gtt gag ctt gtg cag gat gct ctt tct tat ggt gga 595 Pro Ala Gln Ile Val Glu Leu Val Gln Asp Ala Leu Ser Tyr Gly Gly 150 155 160 165 gat gtt att cgt ctt gtc acc ggc aac cca ttg agc agc gat gcc aca 643 Asp Val Ile Arg Leu Val Thr Gly Asn Pro Leu Ser Ser Asp Ala Thr 170 175 180 ctg gct gag atc tct gca gtt tcc gag gct ggc ctg gag ttc cag gtg 691 Leu Ala Glu Ile Ser Ala Val Ser Glu Ala Gly Leu Glu Phe Gln Val 185 190 195 gtt cca ggt atg tct ttg cct gca acg gtt cct gca ttt gcg gga att 739 Val Pro Gly Met Ser Leu Pro Ala Thr Val Pro Ala Phe Ala Gly Ile 200 205 210 gcg ttg ggt tct acc tac acc gaa act gat gtc aac ggt caa aac ttg 787 Ala Leu Gly Ser Thr Tyr Thr Glu Thr Asp Val Asn Gly Gln Asn Leu 215 220 225 gac tgg gat cag ttg gct agc gca cct cag cct ttg gtg ctg cag gcc 835 Asp Trp Asp Gln Leu Ala Ser Ala Pro Gln Pro Leu Val Leu Gln Ala 230 235 240 245 cgc gtg gat gac ctt tcc cgt att gca cag gaa cta aag gcc cgc aat 883 Arg Val Asp Asp Leu Ser Arg Ile Ala Gln Glu Leu Lys Ala Arg Asn 250 255 260 atg tct ttg gaa act cct gtt tct gtc acc gct aac ggc acc acc cgt 931 Met Ser Leu Glu Thr Pro Val Ser Val Thr Ala Asn Gly Thr Thr Arg 265 270 275 ttg cag cgc acc tat gac acc act tta ggt ctg ttg cac aag ctt gat 979 Leu Gln Arg Thr Tyr Asp Thr Thr Leu Gly Leu Leu His Lys Leu Asp 280 285 290 gct gaa cta agc gga cct ttg gtt gtt acc ttg ggc aag ggt gtg 1024 Ala Glu Leu Ser Gly Pro Leu Val Val Thr Leu Gly Lys Gly Val 295 300 305 <210> 822 <211> 308 <212> PRT <213> Corynebacterium glutamicum <400> 822 Met Thr Ile Ala His Lys Pro Glu Met Ala Glu Thr Thr Gly Ile Glu 1 5 10 15 Thr Asn Gln Val Ser Glu Thr Ile Gly Val Glu Ser Leu Thr His Gly 20 25 30 Asn Leu Arg Pro Val Ser Ser Phe Glu Gly Gln His Glu Gly Gln Thr 35 40 45 Glu Glu Leu Leu Pro Gly Lys Val Ile Phe Val Gly Ala Gly Pro Gly 50 55 60 Asn Pro Asp Leu Leu Thr Val Arg Ala Arg Glu Val Leu Gly Asn Ala 65 70 75 80 Val Arg Ala Ile Thr Asp Glu Gln Val Leu Ser Gly Val Arg Ala Phe 85 90 95 Val Ala Thr Glu Ile Pro Val Pro Glu Asp Lys Leu Gln Ala Ala Glu 100 105 110 Asp Glu Tyr Glu Arg Ile Cys Ile Glu Ala Lys Glu Asn Gly Ala Arg 115 120 125 Arg Lys Pro Pro Arg Pro Ala Pro Pro Thr Ala Ala Glu Ile Thr Glu 130 135 140 Val Ser Glu Ala Thr Pro Ala Gln Ile Val Glu Leu Val Gln Asp Ala 145 150 155 160 Leu Ser Tyr Gly Gly Asp Val Ile Arg Leu Val Thr Gly Asn Pro Leu 165 170 175 Ser Ser Asp Ala Thr Leu Ala Glu Ile Ser Ala Val Ser Glu Ala Gly 180 185 190 Leu Glu Phe Gln Val Val Pro Gly Met Ser Leu Pro Ala Thr Val Pro 195 200 205 Ala Phe Ala Gly Ile Ala Leu Gly Ser Thr Tyr Thr Glu Thr Asp Val 210 215 220 Asn Gly Gln Asn Leu Asp Trp Asp Gln Leu Ala Ser Ala Pro Gln Pro 225 230 235 240 Leu Val Leu Gln Ala Arg Val Asp Asp Leu Ser Arg Ile Ala Gln Glu 245 250 255 Leu Lys Ala Arg Asn Met Ser Leu Glu Thr Pro Val Ser Val Thr Ala 260 265 270 Asn Gly Thr Thr Arg Leu Gln Arg Thr Tyr Asp Thr Thr Leu Gly Leu 275 280 285 Leu His Lys Leu Asp Ala Glu Leu Ser Gly Pro Leu Val Val Thr Leu 290 295 300 Gly Lys Gly Val 305 <210> 823 <211> 755 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(732) <223> FRXA00374 <400> 823 acc att tct gtc gaa cca ccg cgc aac cca gcg caa atg gaa cgc gcc 48 Thr Ile Ser Val Glu Pro Pro Arg Asn Pro Ala Gln Met Glu Arg Ala 1 5 10 15 atc aag ggc atc gtc gaa gga cgc tac cag tgg gtt gtc ctc aca agc 96 Ile Lys Gly Ile Val Glu Gly Arg Tyr Gln Trp Val Val Leu Thr Ser 20 25 30 gtc aac gca gtg aag gca gtc tgg aag aaa atc acc gaa ttc ggc ctc 144 Val Asn Ala Val Lys Ala Val Trp Lys Lys Ile Thr Glu Phe Gly Leu 35 40 45 gat tca cgt tcc ttc gcg ggc gtc cgc atc gcc gca gtc ggt gaa aaa 192 Asp Ser Arg Ser Phe Ala Gly Val Arg Ile Ala Ala Val Gly Glu Lys 50 55 60 acc gcc gct gag atc cgc gcg ctc ggc atc acg ccg gag ctt ctg cct 240 Thr Ala Ala Glu Ile Arg Ala Leu Gly Ile Thr Pro Glu Leu Leu Pro 65 70 75 80 gca cgt acc agg caa aat gcg caa ggg ctt gtc gac gtg ttc ccc gaa 288 Ala Arg Thr Arg Gln Asn Ala Gln Gly Leu Val Asp Val Phe Pro Glu 85 90 95 tat ttc gaa gaa ctc gat cca gtc ggc cgt gtc ctc ttg ccg cgc gca 336 Tyr Phe Glu Glu Leu Asp Pro Val Gly Arg Val Leu Leu Pro Arg Ala 100 105 110 gat atc gca acc gac gtg ctt gtc gac ggc ctg acc cac ctt ggt tgg 384 Asp Ile Ala Thr Asp Val Leu Val Asp Gly Leu Thr His Leu Gly Trp 115 120 125 gaa gtc gaa gac gtg gtg gct tac cgc acc gtc cgc gca gca cca cca 432 Glu Val Glu Asp Val Val Ala Tyr Arg Thr Val Arg Ala Ala Pro Pro 130 135 140 agc gct gat atc cga gat atg atc aag acc ggc gga ttt gat gca gtt 480 Ser Ala Asp Ile Arg Asp Met Ile Lys Thr Gly Gly Phe Asp Ala Val 145 150 155 160 gcc ttc acc tct tcg tcg acc gtg aag aac ctc gtt ggt atc gcg ggt 528 Ala Phe Thr Ser Ser Ser Thr Val Lys Asn Leu Val Gly Ile Ala Gly 165 170 175 aaa cca cac cca cgc acc atc gtc gcg tgc atc gga ccc atg act gca 576 Lys Pro His Pro Arg Thr Ile Val Ala Cys Ile Gly Pro Met Thr Ala 180 185 190 gcg acc gct gaa gaa ctg gga ctg cgc gtt gat gtc atg cca gag atc 624 Ala Thr Ala Glu Glu Leu Gly Leu Arg Val Asp Val Met Pro Glu Ile 195 200 205 gcc gaa gta cca gaa ctg atc gac gct ctt gcg gaa cac gtg gcg gat 672 Ala Glu Val Pro Glu Leu Ile Asp Ala Leu Ala Glu His Val Ala Asp 210 215 220 ctg cgc gct aag ggc gag ctg ccg ccg ccg agg aag aaa cgc agg cgt 720 Leu Arg Ala Lys Gly Glu Leu Pro Pro Pro Arg Lys Lys Arg Arg Arg 225 230 235 240 cga aaa gcg tct taaaaggttt ttcactaggg tgt 755 Arg Lys Ala Ser <210> 824 <211> 244 <212> PRT <213> Corynebacterium glutamicum <400> 824 Thr Ile Ser Val Glu Pro Pro Arg Asn Pro Ala Gln Met Glu Arg Ala 1 5 10 15 Ile Lys Gly Ile Val Glu Gly Arg Tyr Gln Trp Val Val Leu Thr Ser 20 25 30 Val Asn Ala Val Lys Ala Val Trp Lys Lys Ile Thr Glu Phe Gly Leu 35 40 45 Asp Ser Arg Ser Phe Ala Gly Val Arg Ile Ala Ala Val Gly Glu Lys 50 55 60 Thr Ala Ala Glu Ile Arg Ala Leu Gly Ile Thr Pro Glu Leu Leu Pro 65 70 75 80 Ala Arg Thr Arg Gln Asn Ala Gln Gly Leu Val Asp Val Phe Pro Glu 85 90 95 Tyr Phe Glu Glu Leu Asp Pro Val Gly Arg Val Leu Leu Pro Arg Ala 100 105 110 Asp Ile Ala Thr Asp Val Leu Val Asp Gly Leu Thr His Leu Gly Trp 115 120 125 Glu Val Glu Asp Val Val Ala Tyr Arg Thr Val Arg Ala Ala Pro Pro 130 135 140 Ser Ala Asp Ile Arg Asp Met Ile Lys Thr Gly Gly Phe Asp Ala Val 145 150 155 160 Ala Phe Thr Ser Ser Ser Thr Val Lys Asn Leu Val Gly Ile Ala Gly 165 170 175 Lys Pro His Pro Arg Thr Ile Val Ala Cys Ile Gly Pro Met Thr Ala 180 185 190 Ala Thr Ala Glu Glu Leu Gly Leu Arg Val Asp Val Met Pro Glu Ile 195 200 205 Ala Glu Val Pro Glu Leu Ile Asp Ala Leu Ala Glu His Val Ala Asp 210 215 220 Leu Arg Ala Lys Gly Glu Leu Pro Pro Pro Arg Lys Lys Arg Arg Arg 225 230 235 240 Arg Lys Ala Ser <210> 825 <211> 1467 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1444) <223> RXN00383 <400> 825 ccatatcttt aaccttggtc atggtgtgct tcctaatacg gtggcggaag atattactga 60 agccgtctcc atcattcatt cttaaactaa gaggagtttc atg cgt ttt gcc atc 115 Met Arg Phe Ala Ile 1 5 atc ggt gca ggc ctt gcg ggt ctg act gct gca tat gag atc cat aaa 163 Ile Gly Ala Gly Leu Ala Gly Leu Thr Ala Ala Tyr Glu Ile His Lys 10 15 20 gct gat ccc act gcc caa atc gat gtg ttg gaa gca ggc gaa cgc att 211 Ala Asp Pro Thr Ala Gln Ile Asp Val Leu Glu Ala Gly Glu Arg Ile 25 30 35 ggc ggc aag ctt ttt acg gtg ccg ttt gct tcc gga cct acc gat att 259 Gly Gly Lys Leu Phe Thr Val Pro Phe Ala Ser Gly Pro Thr Asp Ile 40 45 50 gga gcg gag gcg ttt tta gct gcg cgt tcc gat gcg gtg gag ttt ttt 307 Gly Ala Glu Ala Phe Leu Ala Ala Arg Ser Asp Ala Val Glu Phe Phe 55 60 65 act gag ctt ggg ttg gct gat tct ttg gtc agc ccg tct gct gcg aag 355 Thr Glu Leu Gly Leu Ala Asp Ser Leu Val Ser Pro Ser Ala Ala Lys 70 75 80 85 tct cag tat ttc gcg ggc ggt gcg ctg cat gcg ttc ccc gca ggt gga 403 Ser Gln Tyr Phe Ala Gly Gly Ala Leu His Ala Phe Pro Ala Gly Gly 90 95 100 gtg atg ggt att cca agc aat cca cca gca ggc gcg caa gac acc gct 451 Val Met Gly Ile Pro Ser Asn Pro Pro Ala Gly Ala Gln Asp Thr Ala 105 110 115 ttt gat tgg act cct ggc caa gac att tct gtt ggc gcc tta gtg cgc 499 Phe Asp Trp Thr Pro Gly Gln Asp Ile Ser Val Gly Ala Leu Val Arg 120 125 130 cgt cag tat ggc gat gag atc gtc gat act gtg gtg tct tcg ctg ctt 547 Arg Gln Tyr Gly Asp Glu Ile Val Asp Thr Val Val Ser Ser Leu Leu 135 140 145 ggt ggc gtt tat tcc tcc acc gct gat gat ctg ggt gtg cgc gct tcc 595 Gly Gly Val Tyr Ser Ser Thr Ala Asp Asp Leu Gly Val Arg Ala Ser 150 155 160 165 gtg ccg gca ctt gct gca gcc ctt gat cag ctg gct gag gcc ggc gag 643 Val Pro Ala Leu Ala Ala Ala Leu Asp Gln Leu Ala Glu Ala Gly Glu 170 175 180 ccg gtg act ctg tca gct gcg gtc aag gcc gtg gaa gct cag cgg gaa 691 Pro Val Thr Leu Ser Ala Ala Val Lys Ala Val Glu Ala Gln Arg Glu 185 190 195 gcc gca aaa aca act tca gaa acc cgc ccc gtt ttc cag acc ttc aag 739 Ala Ala Lys Thr Thr Ser Glu Thr Arg Pro Val Phe Gln Thr Phe Lys 200 205 210 ggc gga tac gcg gag ctg tac gaa gcg ttg gca gag caa tgc ggt gca 787 Gly Gly Tyr Ala Glu Leu Tyr Glu Ala Leu Ala Glu Gln Cys Gly Ala 215 220 225 gat att cac ttg gat agt ttc gtt tcc gcc atc acc aaa gat ggt gaa 835 Asp Ile His Leu Asp Ser Phe Val Ser Ala Ile Thr Lys Asp Gly Glu 230 235 240 245 ggt ttt gcc atc aag ggc ggt ggc gaa ggc acc tac gac aag gtg att 883 Gly Phe Ala Ile Lys Gly Gly Gly Glu Gly Thr Tyr Asp Lys Val Ile 250 255 260 ttg gcg gtt ccc gct cca acc gcc gct gtg ctg ctc cgc gac ttg gca 931 Leu Ala Val Pro Ala Pro Thr Ala Ala Val Leu Leu Arg Asp Leu Ala 265 270 275 ccg gcc gca gcg cca cat ttg cgc gca att aag ttg gct tct tca gca 979 Pro Ala Ala Ala Pro His Leu Arg Ala Ile Lys Leu Ala Ser Ser Ala 280 285 290 gtc gtc ggc atg cgt ttc gat tcc agc gag ggc ctg ccc gac aac tcc 1027 Val Val Gly Met Arg Phe Asp Ser Ser Glu Gly Leu Pro Asp Asn Ser 295 300 305 ggc gtc ctg gtc gct gtt aat gag ccg ggc atc acg gcg aag gcc ttc 1075 Gly Val Leu Val Ala Val Asn Glu Pro Gly Ile Thr Ala Lys Ala Phe 310 315 320 325 acg ttc tcc tca aag aag tgg cct cac ctg gag gct cgc ggg ggc gcg 1123 Thr Phe Ser Ser Lys Lys Trp Pro His Leu Glu Ala Arg Gly Gly Ala 330 335 340 ctc gtg cgc gcg tcg ttc ggc agg cta ggc gat gag gcg tcg gca cgc 1171 Leu Val Arg Ala Ser Phe Gly Arg Leu Gly Asp Glu Ala Ser Ala Arg 345 350 355 atg gac gag gat ttg ctt gtc gac gcc gcc ctc gac gat ctc ctc acc 1219 Met Asp Glu Asp Leu Leu Val Asp Ala Ala Leu Asp Asp Leu Leu Thr 360 365 370 ata acc ggg ttc gac ggc cgg gct gcc gga ctg ggt gaa att ttc gtg 1267 Ile Thr Gly Phe Asp Gly Arg Ala Ala Gly Leu Gly Glu Ile Phe Val 375 380 385 cag cgc tgg ttc ggt ggg ctc cca gcc tat gga gtt gat cac att gct 1315 Gln Arg Trp Phe Gly Gly Leu Pro Ala Tyr Gly Val Asp His Ile Ala 390 395 400 405 acc gtt tcg gct gcg cgt gca gag atc gca gcc gtg cct ggc gtg gaa 1363 Thr Val Ser Ala Ala Arg Ala Glu Ile Ala Ala Val Pro Gly Val Glu 410 415 420 gca att ggc gcg tgg gct ggg gga gtg gga gtt ccc gca gtt atc gca 1411 Ala Ile Gly Ala Trp Ala Gly Gly Val Gly Val Pro Ala Val Ile Ala 425 430 435 gat gcc cag gca gca gta cac agg ttg ctg gga taagcaccca aaaacactat 1464 Asp Ala Gln Ala Ala Val His Arg Leu Leu Gly 440 445 tga 1467 <210> 826 <211> 448 <212> PRT <213> Corynebacterium glutamicum <400> 826 Met Arg Phe Ala Ile Ile Gly Ala Gly Leu Ala Gly Leu Thr Ala Ala 1 5 10 15 Tyr Glu Ile His Lys Ala Asp Pro Thr Ala Gln Ile Asp Val Leu Glu 20 25 30 Ala Gly Glu Arg Ile Gly Gly Lys Leu Phe Thr Val Pro Phe Ala Ser 35 40 45 Gly Pro Thr Asp Ile Gly Ala Glu Ala Phe Leu Ala Ala Arg Ser Asp 50 55 60 Ala Val Glu Phe Phe Thr Glu Leu Gly Leu Ala Asp Ser Leu Val Ser 65 70 75 80 Pro Ser Ala Ala Lys Ser Gln Tyr Phe Ala Gly Gly Ala Leu His Ala 85 90 95 Phe Pro Ala Gly Gly Val Met Gly Ile Pro Ser Asn Pro Pro Ala Gly 100 105 110 Ala Gln Asp Thr Ala Phe Asp Trp Thr Pro Gly Gln Asp Ile Ser Val 115 120 125 Gly Ala Leu Val Arg Arg Gln Tyr Gly Asp Glu Ile Val Asp Thr Val 130 135 140 Val Ser Ser Leu Leu Gly Gly Val Tyr Ser Ser Thr Ala Asp Asp Leu 145 150 155 160 Gly Val Arg Ala Ser Val Pro Ala Leu Ala Ala Ala Leu Asp Gln Leu 165 170 175 Ala Glu Ala Gly Glu Pro Val Thr Leu Ser Ala Ala Val Lys Ala Val 180 185 190 Glu Ala Gln Arg Glu Ala Ala Lys Thr Thr Ser Glu Thr Arg Pro Val 195 200 205 Phe Gln Thr Phe Lys Gly Gly Tyr Ala Glu Leu Tyr Glu Ala Leu Ala 210 215 220 Glu Gln Cys Gly Ala Asp Ile His Leu Asp Ser Phe Val Ser Ala Ile 225 230 235 240 Thr Lys Asp Gly Glu Gly Phe Ala Ile Lys Gly Gly Gly Glu Gly Thr 245 250 255 Tyr Asp Lys Val Ile Leu Ala Val Pro Ala Pro Thr Ala Ala Val Leu 260 265 270 Leu Arg Asp Leu Ala Pro Ala Ala Ala Pro His Leu Arg Ala Ile Lys 275 280 285 Leu Ala Ser Ser Ala Val Val Gly Met Arg Phe Asp Ser Ser Glu Gly 290 295 300 Leu Pro Asp Asn Ser Gly Val Leu Val Ala Val Asn Glu Pro Gly Ile 305 310 315 320 Thr Ala Lys Ala Phe Thr Phe Ser Ser Lys Lys Trp Pro His Leu Glu 325 330 335 Ala Arg Gly Gly Ala Leu Val Arg Ala Ser Phe Gly Arg Leu Gly Asp 340 345 350 Glu Ala Ser Ala Arg Met Asp Glu Asp Leu Leu Val Asp Ala Ala Leu 355 360 365 Asp Asp Leu Leu Thr Ile Thr Gly Phe Asp Gly Arg Ala Ala Gly Leu 370 375 380 Gly Glu Ile Phe Val Gln Arg Trp Phe Gly Gly Leu Pro Ala Tyr Gly 385 390 395 400 Val Asp His Ile Ala Thr Val Ser Ala Ala Arg Ala Glu Ile Ala Ala 405 410 415 Val Pro Gly Val Glu Ala Ile Gly Ala Trp Ala Gly Gly Val Gly Val 420 425 430 Pro Ala Val Ile Ala Asp Ala Gln Ala Ala Val His Arg Leu Leu Gly 435 440 445 <210> 827 <211> 382 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(382) <223> FRXA00376 <400> 827 ccatatcttt aaccttggtc atggtgtgct tcctaatacg gtggcggaag atattactga 60 agccgtctcc atcattcatt cttaaactaa gaggagtttc atg cgt ttt gcc atc 115 Met Arg Phe Ala Ile 1 5 atc ggt gca ggc ctt gcg ggt ctg act gct gca tat gag atc cat aaa 163 Ile Gly Ala Gly Leu Ala Gly Leu Thr Ala Ala Tyr Glu Ile His Lys 10 15 20 gct gat ccc act gcc caa atc gat gtg ttg gaa gca ggc gaa cgc att 211 Ala Asp Pro Thr Ala Gln Ile Asp Val Leu Glu Ala Gly Glu Arg Ile 25 30 35 ggc ggc aag ctt ttt acg gtg ccg ttt gct tcc gga cct acc gat att 259 Gly Gly Lys Leu Phe Thr Val Pro Phe Ala Ser Gly Pro Thr Asp Ile 40 45 50 gga gcg gag gcg ttt tta gct gcg cgt tcc gat gcg gtg gag ttt ttt 307 Gly Ala Glu Ala Phe Leu Ala Ala Arg Ser Asp Ala Val Glu Phe Phe 55 60 65 act gag ctt ggg ttg gct gat tct ttg gtc agc ccg tct gct gcg aag 355 Thr Glu Leu Gly Leu Ala Asp Ser Leu Val Ser Pro Ser Ala Ala Lys 70 75 80 85 tct cag tat ttc gcg ggc ggt gcg ctg 382 Ser Gln Tyr Phe Ala Gly Gly Ala Leu 90 <210> 828 <211> 94 <212> PRT <213> Corynebacterium glutamicum <400> 828 Met Arg Phe Ala Ile Ile Gly Ala Gly Leu Ala Gly Leu Thr Ala Ala 1 5 10 15 Tyr Glu Ile His Lys Ala Asp Pro Thr Ala Gln Ile Asp Val Leu Glu 20 25 30 Ala Gly Glu Arg Ile Gly Gly Lys Leu Phe Thr Val Pro Phe Ala Ser 35 40 45 Gly Pro Thr Asp Ile Gly Ala Glu Ala Phe Leu Ala Ala Arg Ser Asp 50 55 60 Ala Val Glu Phe Phe Thr Glu Leu Gly Leu Ala Asp Ser Leu Val Ser 65 70 75 80 Pro Ser Ala Ala Lys Ser Gln Tyr Phe Ala Gly Gly Ala Leu 85 90 <210> 829 <211> 1037 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1014) <223> FRXA00383 <400> 829 gca ggc gcg caa gac acc gct ttt gat tgg act cct ggc caa gac att 48 Ala Gly Ala Gln Asp Thr Ala Phe Asp Trp Thr Pro Gly Gln Asp Ile 1 5 10 15 tct gtt ggc gcc tta gtg cgc cgt cag tat ggc gat gag atc gtc gat 96 Ser Val Gly Ala Leu Val Arg Arg Gln Tyr Gly Asp Glu Ile Val Asp 20 25 30 act gtg gtg tct tcg ctg ctt ggt ggc gtt tat tcc tcc acc gct gat 144 Thr Val Val Ser Ser Leu Leu Gly Gly Val Tyr Ser Ser Thr Ala Asp 35 40 45 gat ctg ggt gtg cgc gct tcc gtg ccg gca ctt gct gca gcc ctt gat 192 Asp Leu Gly Val Arg Ala Ser Val Pro Ala Leu Ala Ala Ala Leu Asp 50 55 60 cag ctg gct gag gcc ggc gag ccg gtg act ctg tca gct gcg gtc aag 240 Gln Leu Ala Glu Ala Gly Glu Pro Val Thr Leu Ser Ala Ala Val Lys 65 70 75 80 gcc gtg gaa gct cag cgg gaa gcc gca aaa aca act tca gaa acc cgc 288 Ala Val Glu Ala Gln Arg Glu Ala Ala Lys Thr Thr Ser Glu Thr Arg 85 90 95 ccc gtt ttc cag acc ttc aag ggc gga tac gcg gag ctg tac gaa gcg 336 Pro Val Phe Gln Thr Phe Lys Gly Gly Tyr Ala Glu Leu Tyr Glu Ala 100 105 110 ttg gca gag caa tgc ggt gca gat att cac ttg gat agt ttc gtt tcc 384 Leu Ala Glu Gln Cys Gly Ala Asp Ile His Leu Asp Ser Phe Val Ser 115 120 125 gcc atc acc aaa gat ggt gaa ggt ttt gcc atc aag ggc ggt ggc gaa 432 Ala Ile Thr Lys Asp Gly Glu Gly Phe Ala Ile Lys Gly Gly Gly Glu 130 135 140 ggc acc tac gac aag gtg att ttg gcg gtt ccc gct cca acc gcc gct 480 Gly Thr Tyr Asp Lys Val Ile Leu Ala Val Pro Ala Pro Thr Ala Ala 145 150 155 160 gtg ctg ctc cgc gac ttg gca ccg gcc gca gcg cca cat ttg cgc gca 528 Val Leu Leu Arg Asp Leu Ala Pro Ala Ala Ala Pro His Leu Arg Ala 165 170 175 att aag ttg gct tct tca gca gtc gtc ggc atg cgt ttc gat tcc agc 576 Ile Lys Leu Ala Ser Ser Ala Val Val Gly Met Arg Phe Asp Ser Ser 180 185 190 gag ggc ctg ccc gac aac tcc ggc gtc ctg gtc gct gtt aat gag ccg 624 Glu Gly Leu Pro Asp Asn Ser Gly Val Leu Val Ala Val Asn Glu Pro 195 200 205 ggc atc acg gcg aag gcc ttc acg ttc tcc tca aag aag tgg cct cac 672 Gly Ile Thr Ala Lys Ala Phe Thr Phe Ser Ser Lys Lys Trp Pro His 210 215 220 ctg gag gct cgc ggg ggc gcg ctc gtg cgc gcg tcg ttc ggc agg cta 720 Leu Glu Ala Arg Gly Gly Ala Leu Val Arg Ala Ser Phe Gly Arg Leu 225 230 235 240 ggc gat gag gcg tcg gca cgc atg gac gag gat ttg ctt gtc gac gcc 768 Gly Asp Glu Ala Ser Ala Arg Met Asp Glu Asp Leu Leu Val Asp Ala 245 250 255 gcc ctc gac gat ctc ctc acc ata acc ggg ttc gac ggc cgg gct gcc 816 Ala Leu Asp Asp Leu Leu Thr Ile Thr Gly Phe Asp Gly Arg Ala Ala 260 265 270 gga ctg ggt gaa att ttc gtg cag cgc tgg ttc ggt ggg ctc cca gcc 864 Gly Leu Gly Glu Ile Phe Val Gln Arg Trp Phe Gly Gly Leu Pro Ala 275 280 285 tat gga gtt gat cac att gct acc gtt tcg gct gcg cgt gca gag atc 912 Tyr Gly Val Asp His Ile Ala Thr Val Ser Ala Ala Arg Ala Glu Ile 290 295 300 gca gcc gtg cct ggc gtg gaa gca att ggc gcg tgg gct ggg gga gtg 960 Ala Ala Val Pro Gly Val Glu Ala Ile Gly Ala Trp Ala Gly Gly Val 305 310 315 320 gga gtt ccc gca gtt atc gca gat gcc cag gca gca gta cac agg ttg 1008 Gly Val Pro Ala Val Ile Ala Asp Ala Gln Ala Ala Val His Arg Leu 325 330 335 ctg gga taagcaccca aaaacactat tga 1037 Leu Gly <210> 830 <211> 338 <212> PRT <213> Corynebacterium glutamicum <400> 830 Ala Gly Ala Gln Asp Thr Ala Phe Asp Trp Thr Pro Gly Gln Asp Ile 1 5 10 15 Ser Val Gly Ala Leu Val Arg Arg Gln Tyr Gly Asp Glu Ile Val Asp 20 25 30 Thr Val Val Ser Ser Leu Leu Gly Gly Val Tyr Ser Ser Thr Ala Asp 35 40 45 Asp Leu Gly Val Arg Ala Ser Val Pro Ala Leu Ala Ala Ala Leu Asp 50 55 60 Gln Leu Ala Glu Ala Gly Glu Pro Val Thr Leu Ser Ala Ala Val Lys 65 70 75 80 Ala Val Glu Ala Gln Arg Glu Ala Ala Lys Thr Thr Ser Glu Thr Arg 85 90 95 Pro Val Phe Gln Thr Phe Lys Gly Gly Tyr Ala Glu Leu Tyr Glu Ala 100 105 110 Leu Ala Glu Gln Cys Gly Ala Asp Ile His Leu Asp Ser Phe Val Ser 115 120 125 Ala Ile Thr Lys Asp Gly Glu Gly Phe Ala Ile Lys Gly Gly Gly Glu 130 135 140 Gly Thr Tyr Asp Lys Val Ile Leu Ala Val Pro Ala Pro Thr Ala Ala 145 150 155 160 Val Leu Leu Arg Asp Leu Ala Pro Ala Ala Ala Pro His Leu Arg Ala 165 170 175 Ile Lys Leu Ala Ser Ser Ala Val Val Gly Met Arg Phe Asp Ser Ser 180 185 190 Glu Gly Leu Pro Asp Asn Ser Gly Val Leu Val Ala Val Asn Glu Pro 195 200 205 Gly Ile Thr Ala Lys Ala Phe Thr Phe Ser Ser Lys Lys Trp Pro His 210 215 220 Leu Glu Ala Arg Gly Gly Ala Leu Val Arg Ala Ser Phe Gly Arg Leu 225 230 235 240 Gly Asp Glu Ala Ser Ala Arg Met Asp Glu Asp Leu Leu Val Asp Ala 245 250 255 Ala Leu Asp Asp Leu Leu Thr Ile Thr Gly Phe Asp Gly Arg Ala Ala 260 265 270 Gly Leu Gly Glu Ile Phe Val Gln Arg Trp Phe Gly Gly Leu Pro Ala 275 280 285 Tyr Gly Val Asp His Ile Ala Thr Val Ser Ala Ala Arg Ala Glu Ile 290 295 300 Ala Ala Val Pro Gly Val Glu Ala Ile Gly Ala Trp Ala Gly Gly Val 305 310 315 320 Gly Val Pro Ala Val Ile Ala Asp Ala Gln Ala Ala Val His Arg Leu 325 330 335 Leu Gly <210> 831 <211> 873 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(850) <223> RXA01253 <400> 831 acgccatcgc agcctgccct cctggccgca tcgaagtcct cgccaactac accgcattcc 60 gagacctcaa aaaggctctg gagaaaggga ccgaacaata atg acc acc ctc aac 115 Met Thr Thr Leu Asn 1 5 atc ggc ctc atc ctc ccc gac gtc ctc gga act tac ggc gac gac ggc 163 Ile Gly Leu Ile Leu Pro Asp Val Leu Gly Thr Tyr Gly Asp Asp Gly 10 15 20 aac gca cta gtc ctg cgc caa cgc gca cgc atg cgt ggc att aat gct 211 Asn Ala Leu Val Leu Arg Gln Arg Ala Arg Met Arg Gly Ile Asn Ala 25 30 35 gaa atc cag cgc gtc acc ctc gac gac gcc gtc cct tcc acc ctt gat 259 Glu Ile Gln Arg Val Thr Leu Asp Asp Ala Val Pro Ser Thr Leu Asp 40 45 50 ctc tac tgc ctc ggc ggc ggc gag gac acc gca cag atc ctt gcc acc 307 Leu Tyr Cys Leu Gly Gly Gly Glu Asp Thr Ala Gln Ile Leu Ala Thr 55 60 65 gaa cac ctc acc aaa gac ggc ggc ctc caa acc gca gcc gcc gca ggc 355 Glu His Leu Thr Lys Asp Gly Gly Leu Gln Thr Ala Ala Ala Ala Gly 70 75 80 85 cgc ccc atc ttc gca gtc tgc gca ggt ctc cag gta ctc ggc gac tcc 403 Arg Pro Ile Phe Ala Val Cys Ala Gly Leu Gln Val Leu Gly Asp Ser 90 95 100 ttc cgc gcc gcc ggc cgt gtc atc gac ggc ctt ggg ctt atc gac gcc 451 Phe Arg Ala Ala Gly Arg Val Ile Asp Gly Leu Gly Leu Ile Asp Ala 105 110 115 acc acc gtc tct tta caa aaa cgc gcc atc gga gaa gtc gaa acg aca 499 Thr Thr Val Ser Leu Gln Lys Arg Ala Ile Gly Glu Val Glu Thr Thr 120 125 130 cca acc cgc gcc gga ttc acc gcc gag ctg acc gaa cga ctc acc ggc 547 Pro Thr Arg Ala Gly Phe Thr Ala Glu Leu Thr Glu Arg Leu Thr Gly 135 140 145 ttc gaa aac cac atg ggc gcc acc ctg ctc ggc ccc gac gcc gaa cca 595 Phe Glu Asn His Met Gly Ala Thr Leu Leu Gly Pro Asp Ala Glu Pro 150 155 160 165 ctc ggc cga gtc gtc cgc ggc gaa ggc aac acc gat gtc tgg gca gcc 643 Leu Gly Arg Val Val Arg Gly Glu Gly Asn Thr Asp Val Trp Ala Ala 170 175 180 tcc gaa aac acc gac gac caa cgc caa caa ttc gcc gaa ggc gcc gtc 691 Ser Glu Asn Thr Asp Asp Gln Arg Gln Gln Phe Ala Glu Gly Ala Val 185 190 195 caa ggc agc atc atc gcc acc tac atg cac ggc ccc gca ctc gcc cga 739 Gln Gly Ser Ile Ile Ala Thr Tyr Met His Gly Pro Ala Leu Ala Arg 200 205 210 aac ccc caa ctc gcc gac ctc atg ctc gca aaa gca atg ggt gtc gcg 787 Asn Pro Gln Leu Ala Asp Leu Met Leu Ala Lys Ala Met Gly Val Ala 215 220 225 ctg aaa gac ctg gag cct ttg gac atc gac gtc atc gac cgc ctc cgc 835 Leu Lys Asp Leu Glu Pro Leu Asp Ile Asp Val Ile Asp Arg Leu Arg 230 235 240 245 gcc gaa cgc ctg gcg tagccccttc taaaccgggt cta 873 Ala Glu Arg Leu Ala 250 <210> 832 <211> 250 <212> PRT <213> Corynebacterium glutamicum <400> 832 Met Thr Thr Leu Asn Ile Gly Leu Ile Leu Pro Asp Val Leu Gly Thr 1 5 10 15 Tyr Gly Asp Asp Gly Asn Ala Leu Val Leu Arg Gln Arg Ala Arg Met 20 25 30 Arg Gly Ile Asn Ala Glu Ile Gln Arg Val Thr Leu Asp Asp Ala Val 35 40 45 Pro Ser Thr Leu Asp Leu Tyr Cys Leu Gly Gly Gly Glu Asp Thr Ala 50 55 60 Gln Ile Leu Ala Thr Glu His Leu Thr Lys Asp Gly Gly Leu Gln Thr 65 70 75 80 Ala Ala Ala Ala Gly Arg Pro Ile Phe Ala Val Cys Ala Gly Leu Gln 85 90 95 Val Leu Gly Asp Ser Phe Arg Ala Ala Gly Arg Val Ile Asp Gly Leu 100 105 110 Gly Leu Ile Asp Ala Thr Thr Val Ser Leu Gln Lys Arg Ala Ile Gly 115 120 125 Glu Val Glu Thr Thr Pro Thr Arg Ala Gly Phe Thr Ala Glu Leu Thr 130 135 140 Glu Arg Leu Thr Gly Phe Glu Asn His Met Gly Ala Thr Leu Leu Gly 145 150 155 160 Pro Asp Ala Glu Pro Leu Gly Arg Val Val Arg Gly Glu Gly Asn Thr 165 170 175 Asp Val Trp Ala Ala Ser Glu Asn Thr Asp Asp Gln Arg Gln Gln Phe 180 185 190 Ala Glu Gly Ala Val Gln Gly Ser Ile Ile Ala Thr Tyr Met His Gly 195 200 205 Pro Ala Leu Ala Arg Asn Pro Gln Leu Ala Asp Leu Met Leu Ala Lys 210 215 220 Ala Met Gly Val Ala Leu Lys Asp Leu Glu Pro Leu Asp Ile Asp Val 225 230 235 240 Ile Asp Arg Leu Arg Ala Glu Arg Leu Ala 245 250 <210> 833 <211> 1044 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1021) <223> RXA02134 <400> 833 tgatgaacga catgtcgaca ttttcttccg ccggcgtcga tggaccccta aacgcctctt 60 ccgaagcgcc cgagcaaaac acggagtaac tttctaagcg atg tcc ggc aaa gca 115 Met Ser Gly Lys Ala 1 5 ggc ttt acc ccc gaa gat ccc gaa gac tca gac aac cgc cac ggg aac 163 Gly Phe Thr Pro Glu Asp Pro Glu Asp Ser Asp Asn Arg His Gly Asn 10 15 20 ccc ctt ttc gaa ggt atc ttt acc gca ctt aat tgg atg acc gtt ctc 211 Pro Leu Phe Glu Gly Ile Phe Thr Ala Leu Asn Trp Met Thr Val Leu 25 30 35 ccc gtc ccc ggc gca tca gtt ttt gat cgc acc acg ggc gcc cgg gta 259 Pro Val Pro Gly Ala Ser Val Phe Asp Arg Thr Thr Gly Ala Arg Val 40 45 50 atg gcc tct ttg ccc ttt gtt ggc ttc gtt ttc gga atg ttc acc gcg 307 Met Ala Ser Leu Pro Phe Val Gly Phe Val Phe Gly Met Phe Thr Ala 55 60 65 atc atc atg tgg gct atc ggc ccc att tca ggg gtg atc cac gtc gat 355 Ile Ile Met Trp Ala Ile Gly Pro Ile Ser Gly Val Ile His Val Asp 70 75 80 85 gga ctt tta gtt gcc gtt ctg atc gtc gcg ttc tgg gaa ctt ctt aat 403 Gly Leu Leu Val Ala Val Leu Ile Val Ala Phe Trp Glu Leu Leu Asn 90 95 100 cgg ttt atg cac ctc gac ggc ctc gca gat gtc tcc gat gct ttg ggt 451 Arg Phe Met His Leu Asp Gly Leu Ala Asp Val Ser Asp Ala Leu Gly 105 110 115 tcc tac gca gcc cca cca cgc gca cga gaa atc ctt gcc gat ccc cgc 499 Ser Tyr Ala Ala Pro Pro Arg Ala Arg Glu Ile Leu Ala Asp Pro Arg 120 125 130 acc gga ctt ttc ggc ctc gcc acc gcc atg ctt tcc gtt ctc ctg cag 547 Thr Gly Leu Phe Gly Leu Ala Thr Ala Met Leu Ser Val Leu Leu Gln 135 140 145 gtc gct gca gtc gca tcg ctt gtc gat tca acc gtg tgg tgg atg atc 595 Val Ala Ala Val Ala Ser Leu Val Asp Ser Thr Val Trp Trp Met Ile 150 155 160 165 tgc ttc atc ccc gtt ctc ggc cgc atc gct gga caa gta acc gca ctg 643 Cys Phe Ile Pro Val Leu Gly Arg Ile Ala Gly Gln Val Thr Ala Leu 170 175 180 aaa aac cac aac gcc ttc tcc ccc acc ggc ttt ggc gca cta gtc atc 691 Lys Asn His Asn Ala Phe Ser Pro Thr Gly Phe Gly Ala Leu Val Ile 185 190 195 gga acg gtg aaa ttt tgg tgg atc gcg ctg tgg ctc ttg gtt act gct 739 Gly Thr Val Lys Phe Trp Trp Ile Ala Leu Trp Leu Leu Val Thr Ala 200 205 210 gcg ttg gct ttt tgg tgc gca gaa tta att tct cca ctt tca ccg ctg 787 Ala Leu Ala Phe Trp Cys Ala Glu Leu Ile Ser Pro Leu Ser Pro Leu 215 220 225 acc agt gtt aac act ccc ttt gtc gct gga cct ttc ccc gct gca atc 835 Thr Ser Val Asn Thr Pro Phe Val Ala Gly Pro Phe Pro Ala Ala Ile 230 235 240 245 aac ccc gcc tgg ctt gga ggc tgg gtt gcg ata acc gca gtc gtg gca 883 Asn Pro Ala Trp Leu Gly Gly Trp Val Ala Ile Thr Ala Val Val Ala 250 255 260 tgt gtt ttc gca gca ctt ttc agc cgc cgc tta tca cga agt ttc ggt 931 Cys Val Phe Ala Ala Leu Phe Ser Arg Arg Leu Ser Arg Ser Phe Gly 265 270 275 gga ctc aac gga gac tgc atc ggc gca tgc att cat ctc ggg gcg tcg 979 Gly Leu Asn Gly Asp Cys Ile Gly Ala Cys Ile His Leu Gly Ala Ser 280 285 290 att tct gca gtg atg ttt gct gtt gtc gcc aat gca atg gtg 1021 Ile Ser Ala Val Met Phe Ala Val Val Ala Asn Ala Met Val 295 300 305 taaagcggtg gcgtcttttg gga 1044 <210> 834 <211> 307 <212> PRT <213> Corynebacterium glutamicum <400> 834 Met Ser Gly Lys Ala Gly Phe Thr Pro Glu Asp Pro Glu Asp Ser Asp 1 5 10 15 Asn Arg His Gly Asn Pro Leu Phe Glu Gly Ile Phe Thr Ala Leu Asn 20 25 30 Trp Met Thr Val Leu Pro Val Pro Gly Ala Ser Val Phe Asp Arg Thr 35 40 45 Thr Gly Ala Arg Val Met Ala Ser Leu Pro Phe Val Gly Phe Val Phe 50 55 60 Gly Met Phe Thr Ala Ile Ile Met Trp Ala Ile Gly Pro Ile Ser Gly 65 70 75 80 Val Ile His Val Asp Gly Leu Leu Val Ala Val Leu Ile Val Ala Phe 85 90 95 Trp Glu Leu Leu Asn Arg Phe Met His Leu Asp Gly Leu Ala Asp Val 100 105 110 Ser Asp Ala Leu Gly Ser Tyr Ala Ala Pro Pro Arg Ala Arg Glu Ile 115 120 125 Leu Ala Asp Pro Arg Thr Gly Leu Phe Gly Leu Ala Thr Ala Met Leu 130 135 140 Ser Val Leu Leu Gln Val Ala Ala Val Ala Ser Leu Val Asp Ser Thr 145 150 155 160 Val Trp Trp Met Ile Cys Phe Ile Pro Val Leu Gly Arg Ile Ala Gly 165 170 175 Gln Val Thr Ala Leu Lys Asn His Asn Ala Phe Ser Pro Thr Gly Phe 180 185 190 Gly Ala Leu Val Ile Gly Thr Val Lys Phe Trp Trp Ile Ala Leu Trp 195 200 205 Leu Leu Val Thr Ala Ala Leu Ala Phe Trp Cys Ala Glu Leu Ile Ser 210 215 220 Pro Leu Ser Pro Leu Thr Ser Val Asn Thr Pro Phe Val Ala Gly Pro 225 230 235 240 Phe Pro Ala Ala Ile Asn Pro Ala Trp Leu Gly Gly Trp Val Ala Ile 245 250 255 Thr Ala Val Val Ala Cys Val Phe Ala Ala Leu Phe Ser Arg Arg Leu 260 265 270 Ser Arg Ser Phe Gly Gly Leu Asn Gly Asp Cys Ile Gly Ala Cys Ile 275 280 285 His Leu Gly Ala Ser Ile Ser Ala Val Met Phe Ala Val Val Ala Asn 290 295 300 Ala Met Val 305 <210> 835 <211> 1197 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1174) <223> RXA02135 <400> 835 cgtgtcgcag cgatttgcga gagggttgtc ttcgtggttg ctggtctgcc actagagttg 60 aaaacgtttt aagaaaacag tcggtttgaa ggagttgtta atg gtt cca gca gag 115 Met Val Pro Ala Glu 1 5 ctt ttt gcg cgt gtg gaa ttt ccg gat cat aaa atc ctg gct cag acg 163 Leu Phe Ala Arg Val Glu Phe Pro Asp His Lys Ile Leu Ala Gln Thr 10 15 20 aag gat ttc cat gac tcc ctc acc aag cca ccc gga tct ttg ggc aag 211 Lys Asp Phe His Asp Ser Leu Thr Lys Pro Pro Gly Ser Leu Gly Lys 25 30 35 ttg gag cag atc ggc tgt ttc att tcc gca tgc cag ggc cag att ccg 259 Leu Glu Gln Ile Gly Cys Phe Ile Ser Ala Cys Gln Gly Gln Ile Pro 40 45 50 cca cgt cca ctc aac aac tca aag atc gtt gtt ttc gct ggc gat cac 307 Pro Arg Pro Leu Asn Asn Ser Lys Ile Val Val Phe Ala Gly Asp His 55 60 65 ggc gtt gca act aaa ggc gtg tcc gcg tac cca tcc tca gta agc ttg 355 Gly Val Ala Thr Lys Gly Val Ser Ala Tyr Pro Ser Ser Val Ser Leu 70 75 80 85 cag atg gct gaa aac att aca aac ggt ggc gcc gcc atc aac gtg att 403 Gln Met Ala Glu Asn Ile Thr Asn Gly Gly Ala Ala Ile Asn Val Ile 90 95 100 gca cgc acc acc ggc acg tcc gtc cga ctt att gat acc tcc ctc gac 451 Ala Arg Thr Thr Gly Thr Ser Val Arg Leu Ile Asp Thr Ser Leu Asp 105 110 115 cac gaa gca tgg ggc gac gag cgc gta tct agg tcc tgc gga tcc atc 499 His Glu Ala Trp Gly Asp Glu Arg Val Ser Arg Ser Cys Gly Ser Ile 120 125 130 gat gtt gaa gac gcc atg acc caa gaa cag gtc gaa cgc gca ctg aag 547 Asp Val Glu Asp Ala Met Thr Gln Glu Gln Val Glu Arg Ala Leu Lys 135 140 145 atc ggt aag cgc att gcg gat caa gaa gtg gac gca ggc gcc gac att 595 Ile Gly Lys Arg Ile Ala Asp Gln Glu Val Asp Ala Gly Ala Asp Ile 150 155 160 165 tta atc ccc ggc gat tta gga att ggc aac acc acc acc gcc gct gcc 643 Leu Ile Pro Gly Asp Leu Gly Ile Gly Asn Thr Thr Thr Ala Ala Ala 170 175 180 ctc gtt gga acg ttc acc ctc gca gag cct gtt gtt gtc gta ggc cgc 691 Leu Val Gly Thr Phe Thr Leu Ala Glu Pro Val Val Val Val Gly Arg 185 190 195 ggc acc gga atc gac gat gaa gcc tgg aaa ctc aaa gtc tcc gcg atc 739 Gly Thr Gly Ile Asp Asp Glu Ala Trp Lys Leu Lys Val Ser Ala Ile 200 205 210 cgc gac gcc atg ttc cgc gcc cgc gac ctg cgc caa gac ccc atc gcc 787 Arg Asp Ala Met Phe Arg Ala Arg Asp Leu Arg Gln Asp Pro Ile Ala 215 220 225 atc gcc cgg aaa atc tct tcc cca gac ctt gca gcc atg gca gca ttc 835 Ile Ala Arg Lys Ile Ser Ser Pro Asp Leu Ala Ala Met Ala Ala Phe 230 235 240 245 att gcc caa gca gca gtt cga cgc acc ccc gtg ctt ctc gac ggc gtt 883 Ile Ala Gln Ala Ala Val Arg Arg Thr Pro Val Leu Leu Asp Gly Val 250 255 260 gta gtc acc gcc gca gcc ctc cta gcc aac aaa ctg gcc cca ggt gcc 931 Val Val Thr Ala Ala Ala Leu Leu Ala Asn Lys Leu Ala Pro Gly Ala 265 270 275 agg cgt tgg ttc atc gca gga cac cgc tcc acc gaa cca gcg cat tcc 979 Arg Arg Trp Phe Ile Ala Gly His Arg Ser Thr Glu Pro Ala His Ser 280 285 290 gta gct cta aac gca ctg gcc ctt gat ccc atc ctg gaa ctt gga atg 1027 Val Ala Leu Asn Ala Leu Ala Leu Asp Pro Ile Leu Glu Leu Gly Met 295 300 305 tcc ctt ggc gaa ggc tcc ggc gca gcc acc gca ctc ccc ctg gtc aag 1075 Ser Leu Gly Glu Gly Ser Gly Ala Ala Thr Ala Leu Pro Leu Val Lys 310 315 320 325 att gcc gtt gac ctg atg aac gac atg tcg aca ttt tct tcc gcc ggc 1123 Ile Ala Val Asp Leu Met Asn Asp Met Ser Thr Phe Ser Ser Ala Gly 330 335 340 gtc gat gga ccc cta aac gcc tct tcc gaa gcg ccc gag caa aac acg 1171 Val Asp Gly Pro Leu Asn Ala Ser Ser Glu Ala Pro Glu Gln Asn Thr 345 350 355 gag taactttcta agcgatgtcc ggc 1197 Glu <210> 836 <211> 358 <212> PRT <213> Corynebacterium glutamicum <400> 836 Met Val Pro Ala Glu Leu Phe Ala Arg Val Glu Phe Pro Asp His Lys 1 5 10 15 Ile Leu Ala Gln Thr Lys Asp Phe His Asp Ser Leu Thr Lys Pro Pro 20 25 30 Gly Ser Leu Gly Lys Leu Glu Gln Ile Gly Cys Phe Ile Ser Ala Cys 35 40 45 Gln Gly Gln Ile Pro Pro Arg Pro Leu Asn Asn Ser Lys Ile Val Val 50 55 60 Phe Ala Gly Asp His Gly Val Ala Thr Lys Gly Val Ser Ala Tyr Pro 65 70 75 80 Ser Ser Val Ser Leu Gln Met Ala Glu Asn Ile Thr Asn Gly Gly Ala 85 90 95 Ala Ile Asn Val Ile Ala Arg Thr Thr Gly Thr Ser Val Arg Leu Ile 100 105 110 Asp Thr Ser Leu Asp His Glu Ala Trp Gly Asp Glu Arg Val Ser Arg 115 120 125 Ser Cys Gly Ser Ile Asp Val Glu Asp Ala Met Thr Gln Glu Gln Val 130 135 140 Glu Arg Ala Leu Lys Ile Gly Lys Arg Ile Ala Asp Gln Glu Val Asp 145 150 155 160 Ala Gly Ala Asp Ile Leu Ile Pro Gly Asp Leu Gly Ile Gly Asn Thr 165 170 175 Thr Thr Ala Ala Ala Leu Val Gly Thr Phe Thr Leu Ala Glu Pro Val 180 185 190 Val Val Val Gly Arg Gly Thr Gly Ile Asp Asp Glu Ala Trp Lys Leu 195 200 205 Lys Val Ser Ala Ile Arg Asp Ala Met Phe Arg Ala Arg Asp Leu Arg 210 215 220 Gln Asp Pro Ile Ala Ile Ala Arg Lys Ile Ser Ser Pro Asp Leu Ala 225 230 235 240 Ala Met Ala Ala Phe Ile Ala Gln Ala Ala Val Arg Arg Thr Pro Val 245 250 255 Leu Leu Asp Gly Val Val Val Thr Ala Ala Ala Leu Leu Ala Asn Lys 260 265 270 Leu Ala Pro Gly Ala Arg Arg Trp Phe Ile Ala Gly His Arg Ser Thr 275 280 285 Glu Pro Ala His Ser Val Ala Leu Asn Ala Leu Ala Leu Asp Pro Ile 290 295 300 Leu Glu Leu Gly Met Ser Leu Gly Glu Gly Ser Gly Ala Ala Thr Ala 305 310 315 320 Leu Pro Leu Val Lys Ile Ala Val Asp Leu Met Asn Asp Met Ser Thr 325 330 335 Phe Ser Ser Ala Gly Val Asp Gly Pro Leu Asn Ala Ser Ser Glu Ala 340 345 350 Pro Glu Gln Asn Thr Glu 355 <210> 837 <211> 645 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(622) <223> RXA02136 <400> 837 tggttttggt ctgggttact acgcgtattc ccgcaccatt cagcctcgta agtggcgtac 60 ccctcgtgca cgcgttgaaa ttggtgctga agtctagcgc atg cgc acg tta gtt 115 Met Arg Thr Leu Val 1 5 ctt ggc ggg gcc agg tct ggt aag tct gct ttt gca gaa tca ctt gtt 163 Leu Gly Gly Ala Arg Ser Gly Lys Ser Ala Phe Ala Glu Ser Leu Val 10 15 20 gga tct ggt ccc gtt ttg tat gtc gca acg gca agg cct tcg gga gat 211 Gly Ser Gly Pro Val Leu Tyr Val Ala Thr Ala Arg Pro Ser Gly Asp 25 30 35 gat cct gaa ttc gcc gag cgc att gcg gtt cat gcg gag cgg cgc cca 259 Asp Pro Glu Phe Ala Glu Arg Ile Ala Val His Ala Glu Arg Arg Pro 40 45 50 acg tct tgg gtg ttg gac gag gag ggg gac gtc gat aag ctt ctt gcc 307 Thr Ser Trp Val Leu Asp Glu Glu Gly Asp Val Asp Lys Leu Leu Ala 55 60 65 tcg cca ccg gcc atg ccg gtg ctc gtt gat gac ctg ggc acc tgg ctc 355 Ser Pro Pro Ala Met Pro Val Leu Val Asp Asp Leu Gly Thr Trp Leu 70 75 80 85 acg cac gcc acc gat gcg tgc gac ggt tgg gag gcg agt tcg gcg cag 403 Thr His Ala Thr Asp Ala Cys Asp Gly Trp Glu Ala Ser Ser Ala Gln 90 95 100 ctt gag gcc aag atg gat ttg ctt atc gac gcc atc ctc cac ttt cag 451 Leu Glu Ala Lys Met Asp Leu Leu Ile Asp Ala Ile Leu His Phe Gln 105 110 115 ggc gaa gat ctg gta att gtt tca cct gaa gtt ggt atg gga atc gtc 499 Gly Glu Asp Leu Val Ile Val Ser Pro Glu Val Gly Met Gly Ile Val 120 125 130 ccg gaa tat aaa tct ggg cgc ctt ttt cgt gat cgc atc ggc aca ctt 547 Pro Glu Tyr Lys Ser Gly Arg Leu Phe Arg Asp Arg Ile Gly Thr Leu 135 140 145 aat cag cgt gtc gca gcg att tgc gag agg gtt gtc ttc gtg gtt gct 595 Asn Gln Arg Val Ala Ala Ile Cys Glu Arg Val Val Phe Val Val Ala 150 155 160 165 ggt ctg cca cta gag ttg aaa acg ttt taagaaaaca gtcggtttga 642 Gly Leu Pro Leu Glu Leu Lys Thr Phe 170 agg 645 <210> 838 <211> 174 <212> PRT <213> Corynebacterium glutamicum <400> 838 Met Arg Thr Leu Val Leu Gly Gly Ala Arg Ser Gly Lys Ser Ala Phe 1 5 10 15 Ala Glu Ser Leu Val Gly Ser Gly Pro Val Leu Tyr Val Ala Thr Ala 20 25 30 Arg Pro Ser Gly Asp Asp Pro Glu Phe Ala Glu Arg Ile Ala Val His 35 40 45 Ala Glu Arg Arg Pro Thr Ser Trp Val Leu Asp Glu Glu Gly Asp Val 50 55 60 Asp Lys Leu Leu Ala Ser Pro Pro Ala Met Pro Val Leu Val Asp Asp 65 70 75 80 Leu Gly Thr Trp Leu Thr His Ala Thr Asp Ala Cys Asp Gly Trp Glu 85 90 95 Ala Ser Ser Ala Gln Leu Glu Ala Lys Met Asp Leu Leu Ile Asp Ala 100 105 110 Ile Leu His Phe Gln Gly Glu Asp Leu Val Ile Val Ser Pro Glu Val 115 120 125 Gly Met Gly Ile Val Pro Glu Tyr Lys Ser Gly Arg Leu Phe Arg Asp 130 135 140 Arg Ile Gly Thr Leu Asn Gln Arg Val Ala Ala Ile Cys Glu Arg Val 145 150 155 160 Val Phe Val Val Ala Gly Leu Pro Leu Glu Leu Lys Thr Phe 165 170 <210> 839 <211> 575 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(552) <223> RXN03114 <400> 839 act ccg ggg cat ttt gtt gcg ctc gcg cgg gag att gcg ggc gcg gtg 48 Thr Pro Gly His Phe Val Ala Leu Ala Arg Glu Ile Ala Gly Ala Val 1 5 10 15 cgc cgc gag ttg acg gtg ggg ttg gat gct ggt gac ggt ccg att tta 96 Arg Arg Glu Leu Thr Val Gly Leu Asp Ala Gly Asp Gly Pro Ile Leu 20 25 30 agg cag agc ttt gat gtt ggt ttt ttg ctt gtc gac gcc tcc ttc cac 144 Arg Gln Ser Phe Asp Val Gly Phe Leu Leu Val Asp Ala Ser Phe His 35 40 45 att cat atc aat ggc gtg tct act ggg cag tcg gtt gcg ccg gat gat 192 Ile His Ile Asn Gly Val Ser Thr Gly Gln Ser Val Ala Pro Asp Asp 50 55 60 gta gtt gag gtg gtg cgt ggt ttg gct gat gct tcg gag ttg tcc gtg 240 Val Val Glu Val Val Arg Gly Leu Ala Asp Ala Ser Glu Leu Ser Val 65 70 75 80 gaa agt gtt gct gag ttg tgt act ccc gtg gca ccg gtt tca tta tct 288 Glu Ser Val Ala Glu Leu Cys Thr Pro Val Ala Pro Val Ser Leu Ser 85 90 95 gag gca cag ggg aat cct gcg cct att ggg tgg ttg gag cat gat ggc 336 Glu Ala Gln Gly Asn Pro Ala Pro Ile Gly Trp Leu Glu His Asp Gly 100 105 110 gtg gtg tcg ttg ggt gcg ggt att cca ggg ggg cgg gtg gag gct cgt 384 Val Val Ser Leu Gly Ala Gly Ile Pro Gly Gly Arg Val Glu Ala Arg 115 120 125 tta gcg cgt ttt att gcg gtg att gag gcg gag acc act att acc cca 432 Leu Ala Arg Phe Ile Ala Val Ile Glu Ala Glu Thr Thr Ile Thr Pro 130 135 140 tgg aat tcg ttg atc att cat gat ttg tat gag ggt gtt gca gaa cag 480 Trp Asn Ser Leu Ile Ile His Asp Leu Tyr Glu Gly Val Ala Glu Gln 145 150 155 160 gtg gtg aag gtt ctg gct ccc atg ggg ttg gtt ttt gat gct aat tca 528 Val Val Lys Val Leu Ala Pro Met Gly Leu Val Phe Asp Ala Asn Ser 165 170 175 ccg ctt ctg gag tca ccg gct ttg taactcgcca ttggtgcacg tct 575 Pro Leu Leu Glu Ser Pro Ala Leu 180 <210> 840 <211> 184 <212> PRT <213> Corynebacterium glutamicum <400> 840 Thr Pro Gly His Phe Val Ala Leu Ala Arg Glu Ile Ala Gly Ala Val 1 5 10 15 Arg Arg Glu Leu Thr Val Gly Leu Asp Ala Gly Asp Gly Pro Ile Leu 20 25 30 Arg Gln Ser Phe Asp Val Gly Phe Leu Leu Val Asp Ala Ser Phe His 35 40 45 Ile His Ile Asn Gly Val Ser Thr Gly Gln Ser Val Ala Pro Asp Asp 50 55 60 Val Val Glu Val Val Arg Gly Leu Ala Asp Ala Ser Glu Leu Ser Val 65 70 75 80 Glu Ser Val Ala Glu Leu Cys Thr Pro Val Ala Pro Val Ser Leu Ser 85 90 95 Glu Ala Gln Gly Asn Pro Ala Pro Ile Gly Trp Leu Glu His Asp Gly 100 105 110 Val Val Ser Leu Gly Ala Gly Ile Pro Gly Gly Arg Val Glu Ala Arg 115 120 125 Leu Ala Arg Phe Ile Ala Val Ile Glu Ala Glu Thr Thr Ile Thr Pro 130 135 140 Trp Asn Ser Leu Ile Ile His Asp Leu Tyr Glu Gly Val Ala Glu Gln 145 150 155 160 Val Val Lys Val Leu Ala Pro Met Gly Leu Val Phe Asp Ala Asn Ser 165 170 175 Pro Leu Leu Glu Ser Pro Ala Leu 180 <210> 841 <211> 1200 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1177) <223> RXN01810 <400> 841 ccaccaccac aatgttgctc atcctcgcgg cgttcgttgt cgcaggtggc tccatgactc 60 gcttcaccgt cggcaacccg actggaaaat aaggcttcac atg aat aac gct ttt 115 Met Asn Asn Ala Phe 1 5 cga cgc acc ctt aca tcc gta gtc ctc gcc gct agc ttg gcc tta acg 163 Arg Arg Thr Leu Thr Ser Val Val Leu Ala Ala Ser Leu Ala Leu Thr 10 15 20 gcc tgc gca agc tgg gat tca cct acg gca tct tcc aat ggt gat ctg 211 Ala Cys Ala Ser Trp Asp Ser Pro Thr Ala Ser Ser Asn Gly Asp Leu 25 30 35 att gag gag atc cag gca agc tcc acc tca aca gat ccg cgc acc ttc 259 Ile Glu Glu Ile Gln Ala Ser Ser Thr Ser Thr Asp Pro Arg Thr Phe 40 45 50 aca ggc ttg agc atc gtg gaa gat atc ggc gat gtg gtt ccc gta acc 307 Thr Gly Leu Ser Ile Val Glu Asp Ile Gly Asp Val Val Pro Val Thr 55 60 65 gac aac gcc tca cca gct ctg cca gtt tct ttg acc gac gct gat ggc 355 Asp Asn Ala Ser Pro Ala Leu Pro Val Ser Leu Thr Asp Ala Asp Gly 70 75 80 85 aac gac gtg gtg gtg gag aac gtg tcc cgc atc ctc cca ctg gat ctc 403 Asn Asp Val Val Val Glu Asn Val Ser Arg Ile Leu Pro Leu Asp Leu 90 95 100 tac gga acc tat tcc aaa acc atc gct ggc ctg gga ctc gtg gac aat 451 Tyr Gly Thr Tyr Ser Lys Thr Ile Ala Gly Leu Gly Leu Val Asp Asn 105 110 115 att gtg ggt cgt act gtt agt tcc acc gag cct gca ttg gcg gac att 499 Ile Val Gly Arg Thr Val Ser Ser Thr Glu Pro Ala Leu Ala Asp Ile 120 125 130 gag gtg gtc acc act ggc gga cac acc ctc aat gct gaa gcg atc ctt 547 Glu Val Val Thr Thr Gly Gly His Thr Leu Asn Ala Glu Ala Ile Leu 135 140 145 aat tta cat ccg act ttg gtg atc atc gac cac tcg atc ggc cca cgc 595 Asn Leu His Pro Thr Leu Val Ile Ile Asp His Ser Ile Gly Pro Arg 150 155 160 165 gaa gtc atc gat cag atc cgc gca gct ggt gtc gcc acg gtg atc atg 643 Glu Val Ile Asp Gln Ile Arg Ala Ala Gly Val Ala Thr Val Ile Met 170 175 180 tcg ccg cag cgt tcc att gcc tca att ggc gac gac atc cgc gac atc 691 Ser Pro Gln Arg Ser Ile Ala Ser Ile Gly Asp Asp Ile Arg Asp Ile 185 190 195 gcc tcc gtc gtt gga ctt cct gaa gaa ggg gag aag ctc gcg gaa cgt 739 Ala Ser Val Val Gly Leu Pro Glu Glu Gly Glu Lys Leu Ala Glu Arg 200 205 210 tcc gtt gct gaa gtc gaa gag gcc agc acg gtt gtc gat gaa ctc acc 787 Ser Val Ala Glu Val Glu Glu Ala Ser Thr Val Val Asp Glu Leu Thr 215 220 225 cca gaa gat ccc ctc aaa atg gta ttc ctc tat gcc cgc gga act ggt 835 Pro Glu Asp Pro Leu Lys Met Val Phe Leu Tyr Ala Arg Gly Thr Gly 230 235 240 245 gga gtg ttc ttc att ttg ggc gat gcc tat ggt gga cgc gat ctc att 883 Gly Val Phe Phe Ile Leu Gly Asp Ala Tyr Gly Gly Arg Asp Leu Ile 250 255 260 gaa ggc ctg ggc ggc gtc gac atg gct gct gaa aag ggc atc atg gat 931 Glu Gly Leu Gly Gly Val Asp Met Ala Ala Glu Lys Gly Ile Met Asp 265 270 275 ctg gca cca gcc aac gcg gaa gca ctt gcc gaa cta aat cca gac gtc 979 Leu Ala Pro Ala Asn Ala Glu Ala Leu Ala Glu Leu Asn Pro Asp Val 280 285 290 ttc gtg atg atg tcg gaa gga cta gtc tcg aca gga ggt atc gac ggt 1027 Phe Val Met Met Ser Glu Gly Leu Val Ser Thr Gly Gly Ile Asp Gly 295 300 305 ctt atg gaa cgc ccc ggc att gct cag aca acc gcc gga caa aac caa 1075 Leu Met Glu Arg Pro Gly Ile Ala Gln Thr Thr Ala Gly Gln Asn Gln 310 315 320 325 cga gta ctg gcg ctt ccc gat ggt caa tca ttg gcc ttt ggt gcc caa 1123 Arg Val Leu Ala Leu Pro Asp Gly Gln Ser Leu Ala Phe Gly Ala Gln 330 335 340 act ggc gag ttg ttg ctc cgc gca tcc cgc gaa ctg tat gtg cag ggc 1171 Thr Gly Glu Leu Leu Leu Arg Ala Ser Arg Glu Leu Tyr Val Gln Gly 345 350 355 ggc gag tagatggttg tgaaggaggt tga 1200 Gly Glu <210> 842 <211> 359 <212> PRT <213> Corynebacterium glutamicum <400> 842 Met Asn Asn Ala Phe Arg Arg Thr Leu Thr Ser Val Val Leu Ala Ala 1 5 10 15 Ser Leu Ala Leu Thr Ala Cys Ala Ser Trp Asp Ser Pro Thr Ala Ser 20 25 30 Ser Asn Gly Asp Leu Ile Glu Glu Ile Gln Ala Ser Ser Thr Ser Thr 35 40 45 Asp Pro Arg Thr Phe Thr Gly Leu Ser Ile Val Glu Asp Ile Gly Asp 50 55 60 Val Val Pro Val Thr Asp Asn Ala Ser Pro Ala Leu Pro Val Ser Leu 65 70 75 80 Thr Asp Ala Asp Gly Asn Asp Val Val Val Glu Asn Val Ser Arg Ile 85 90 95 Leu Pro Leu Asp Leu Tyr Gly Thr Tyr Ser Lys Thr Ile Ala Gly Leu 100 105 110 Gly Leu Val Asp Asn Ile Val Gly Arg Thr Val Ser Ser Thr Glu Pro 115 120 125 Ala Leu Ala Asp Ile Glu Val Val Thr Thr Gly Gly His Thr Leu Asn 130 135 140 Ala Glu Ala Ile Leu Asn Leu His Pro Thr Leu Val Ile Ile Asp His 145 150 155 160 Ser Ile Gly Pro Arg Glu Val Ile Asp Gln Ile Arg Ala Ala Gly Val 165 170 175 Ala Thr Val Ile Met Ser Pro Gln Arg Ser Ile Ala Ser Ile Gly Asp 180 185 190 Asp Ile Arg Asp Ile Ala Ser Val Val Gly Leu Pro Glu Glu Gly Glu 195 200 205 Lys Leu Ala Glu Arg Ser Val Ala Glu Val Glu Glu Ala Ser Thr Val 210 215 220 Val Asp Glu Leu Thr Pro Glu Asp Pro Leu Lys Met Val Phe Leu Tyr 225 230 235 240 Ala Arg Gly Thr Gly Gly Val Phe Phe Ile Leu Gly Asp Ala Tyr Gly 245 250 255 Gly Arg Asp Leu Ile Glu Gly Leu Gly Gly Val Asp Met Ala Ala Glu 260 265 270 Lys Gly Ile Met Asp Leu Ala Pro Ala Asn Ala Glu Ala Leu Ala Glu 275 280 285 Leu Asn Pro Asp Val Phe Val Met Met Ser Glu Gly Leu Val Ser Thr 290 295 300 Gly Gly Ile Asp Gly Leu Met Glu Arg Pro Gly Ile Ala Gln Thr Thr 305 310 315 320 Ala Gly Gln Asn Gln Arg Val Leu Ala Leu Pro Asp Gly Gln Ser Leu 325 330 335 Ala Phe Gly Ala Gln Thr Gly Glu Leu Leu Leu Arg Ala Ser Arg Glu 340 345 350 Leu Tyr Val Gln Gly Gly Glu 355 <210> 843 <211> 963 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(933) <223> RXS03205 <400> 843 gat tcc ggc att ccc acg cag ttg gtg gag ggc agc tgg ttt gaa ccg 48 Asp Ser Gly Ile Pro Thr Gln Leu Val Glu Gly Ser Trp Phe Glu Pro 1 5 10 15 gtt cgc ggg cgc acc ttt gac cgc atc atc gcc aac ccg ccg ttc gtg 96 Val Arg Gly Arg Thr Phe Asp Arg Ile Ile Ala Asn Pro Pro Phe Val 20 25 30 gtg gga cca ccg gaa att ggg cat gtg tac cgc gat tcc ggc atg gat 144 Val Gly Pro Pro Glu Ile Gly His Val Tyr Arg Asp Ser Gly Met Asp 35 40 45 cta gac ggc gcg acc gcg ttg gtg gtc aaa gaa gcc tgc gcg cat ctc 192 Leu Asp Gly Ala Thr Ala Leu Val Val Lys Glu Ala Cys Ala His Leu 50 55 60 aac cct ggt ggc acc gct cac ctg ctc ggc gca tgg gtg cat tcc gcg 240 Asn Pro Gly Gly Thr Ala His Leu Leu Gly Ala Trp Val His Ser Ala 65 70 75 80 gat caa tcg tgg cag cag cgc gtt gca gaa tgg ttg ccg gat aac ggt 288 Asp Gln Ser Trp Gln Gln Arg Val Ala Glu Trp Leu Pro Asp Asn Gly 85 90 95 tat gtt gct tgg gtt att gag cgc gac gcc gtg agc ccc gcg cag tat 336 Tyr Val Ala Trp Val Ile Glu Arg Asp Ala Val Ser Pro Ala Gln Tyr 100 105 110 gtg ggc acg tgg ctt agt gat gag tcc ctc gat ctg cgt agc ccc gag 384 Val Gly Thr Trp Leu Ser Asp Glu Ser Leu Asp Leu Arg Ser Pro Glu 115 120 125 gca gca gca cgc acc acc gcg tgg ctt aac cac ttt gaa aaa gcc aag 432 Ala Ala Ala Arg Thr Thr Ala Trp Leu Asn His Phe Glu Lys Ala Lys 130 135 140 gtt caa ggc gtt ggt ttt ggt ttc atc gcc atc caa cgt ctg gag gaa 480 Val Gln Gly Val Gly Phe Gly Phe Ile Ala Ile Gln Arg Leu Glu Glu 145 150 155 160 gac gag gcg gat gag aaa tcc gat atc ttg gct gaa tcc atg acc cag 528 Asp Glu Ala Asp Glu Lys Ser Asp Ile Leu Ala Glu Ser Met Thr Gln 165 170 175 tac ttc gag gat cct ctc ggc cct gaa att gag gag tac ttc acc cgc 576 Tyr Phe Glu Asp Pro Leu Gly Pro Glu Ile Glu Glu Tyr Phe Thr Arg 180 185 190 acc gca tgg ctt cgt gaa caa act cgc gat tcc att ctg agc tcc cgc 624 Thr Ala Trp Leu Arg Glu Gln Thr Arg Asp Ser Ile Leu Ser Ser Arg 195 200 205 ttc aaa gtt cgc cct ggc gtg gcc cgg gaa caa atc agc ctg gcc gat 672 Phe Lys Val Arg Pro Gly Val Ala Arg Glu Gln Ile Ser Leu Ala Asp 210 215 220 gcg gaa gaa ggc atg ggc ttt agt cct gtc acg ttg agg ctc acc cgc 720 Ala Glu Glu Gly Met Gly Phe Ser Pro Val Thr Leu Arg Leu Thr Arg 225 230 235 240 acc gat ggt cct cgt tgg tcc cat gat gtt gat gag cat gtg gct tcc 768 Thr Asp Gly Pro Arg Trp Ser His Asp Val Asp Glu His Val Ala Ser 245 250 255 atc gtc gca gga ctt aac cca cat gga ctc ccc ttt gaa gaa atc ctg 816 Ile Val Ala Gly Leu Asn Pro His Gly Leu Pro Phe Glu Glu Ile Leu 260 265 270 gaa atg tac gcg atg gct caa ggt atc gag gga gaa tcc ctg cac aac 864 Glu Met Tyr Ala Met Ala Gln Gly Ile Glu Gly Glu Ser Leu His Asn 275 280 285 ggc gcc att gcg gcg ttg gtg gat ctc atc cgc cac gga ttg gtg ttg 912 Gly Ala Ile Ala Ala Leu Val Asp Leu Ile Arg His Gly Leu Val Leu 290 295 300 ccc gct gat ctt ctc gat tct taaataagga ctgattgtga aagccgtttt 963 Pro Ala Asp Leu Leu Asp Ser 305 310 <210> 844 <211> 311 <212> PRT <213> Corynebacterium glutamicum <400> 844 Asp Ser Gly Ile Pro Thr Gln Leu Val Glu Gly Ser Trp Phe Glu Pro 1 5 10 15 Val Arg Gly Arg Thr Phe Asp Arg Ile Ile Ala Asn Pro Pro Phe Val 20 25 30 Val Gly Pro Pro Glu Ile Gly His Val Tyr Arg Asp Ser Gly Met Asp 35 40 45 Leu Asp Gly Ala Thr Ala Leu Val Val Lys Glu Ala Cys Ala His Leu 50 55 60 Asn Pro Gly Gly Thr Ala His Leu Leu Gly Ala Trp Val His Ser Ala 65 70 75 80 Asp Gln Ser Trp Gln Gln Arg Val Ala Glu Trp Leu Pro Asp Asn Gly 85 90 95 Tyr Val Ala Trp Val Ile Glu Arg Asp Ala Val Ser Pro Ala Gln Tyr 100 105 110 Val Gly Thr Trp Leu Ser Asp Glu Ser Leu Asp Leu Arg Ser Pro Glu 115 120 125 Ala Ala Ala Arg Thr Thr Ala Trp Leu Asn His Phe Glu Lys Ala Lys 130 135 140 Val Gln Gly Val Gly Phe Gly Phe Ile Ala Ile Gln Arg Leu Glu Glu 145 150 155 160 Asp Glu Ala Asp Glu Lys Ser Asp Ile Leu Ala Glu Ser Met Thr Gln 165 170 175 Tyr Phe Glu Asp Pro Leu Gly Pro Glu Ile Glu Glu Tyr Phe Thr Arg 180 185 190 Thr Ala Trp Leu Arg Glu Gln Thr Arg Asp Ser Ile Leu Ser Ser Arg 195 200 205 Phe Lys Val Arg Pro Gly Val Ala Arg Glu Gln Ile Ser Leu Ala Asp 210 215 220 Ala Glu Glu Gly Met Gly Phe Ser Pro Val Thr Leu Arg Leu Thr Arg 225 230 235 240 Thr Asp Gly Pro Arg Trp Ser His Asp Val Asp Glu His Val Ala Ser 245 250 255 Ile Val Ala Gly Leu Asn Pro His Gly Leu Pro Phe Glu Glu Ile Leu 260 265 270 Glu Met Tyr Ala Met Ala Gln Gly Ile Glu Gly Glu Ser Leu His Asn 275 280 285 Gly Ala Ile Ala Ala Leu Val Asp Leu Ile Arg His Gly Leu Val Leu 290 295 300 Pro Ala Asp Leu Leu Asp Ser 305 310 <210> 845 <211> 956 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(933) <223> FRXA00306 <400> 845 gat tcc ggc att ccc acg cag ttg gtg gag ggc agc tgg ttt gaa ccg 48 Asp Ser Gly Ile Pro Thr Gln Leu Val Glu Gly Ser Trp Phe Glu Pro 1 5 10 15 gtt cgc ggg cgc acc ttt gac cgc atc atc gcc aac ccg ccg ttc gtg 96 Val Arg Gly Arg Thr Phe Asp Arg Ile Ile Ala Asn Pro Pro Phe Val 20 25 30 gtg gga cca ccg gaa att ggg cat gtg tac cgc gat tcc ggc atg gat 144 Val Gly Pro Pro Glu Ile Gly His Val Tyr Arg Asp Ser Gly Met Asp 35 40 45 cta gac ggc gcg acc gcg ttg gtg gtc aaa gaa gcc tgc gcg cat ctc 192 Leu Asp Gly Ala Thr Ala Leu Val Val Lys Glu Ala Cys Ala His Leu 50 55 60 aac cct ggt ggc acc gct cac ctg ctc ggc gca tgg gtg cat tcc gcg 240 Asn Pro Gly Gly Thr Ala His Leu Leu Gly Ala Trp Val His Ser Ala 65 70 75 80 gat caa tcg tgg cag cag cgc gtt gca gaa tgg ttg ccg gat aac ggt 288 Asp Gln Ser Trp Gln Gln Arg Val Ala Glu Trp Leu Pro Asp Asn Gly 85 90 95 tat gtt gct tgg gtt att gag cgc gac gcc gtg agc ccc gcg cag tat 336 Tyr Val Ala Trp Val Ile Glu Arg Asp Ala Val Ser Pro Ala Gln Tyr 100 105 110 gtg ggc acg tgg ctt agt gat gag tcc ctc gat ctg cgt agc ccc gag 384 Val Gly Thr Trp Leu Ser Asp Glu Ser Leu Asp Leu Arg Ser Pro Glu 115 120 125 gca gca gca cgc acc acc gcg tgg ctt aac cac ttt gaa aaa gcc aag 432 Ala Ala Ala Arg Thr Thr Ala Trp Leu Asn His Phe Glu Lys Ala Lys 130 135 140 gtt caa ggc gtt ggt ttt ggt ttc atc gcc atc caa cgt ctg gag gaa 480 Val Gln Gly Val Gly Phe Gly Phe Ile Ala Ile Gln Arg Leu Glu Glu 145 150 155 160 gac gag gcg gat gag aaa tcc gat atc ttg gct gaa tcc atg acc cag 528 Asp Glu Ala Asp Glu Lys Ser Asp Ile Leu Ala Glu Ser Met Thr Gln 165 170 175 tac ttc gag gat cct ctc ggc cct gaa att gag gag tac ttc acc cgc 576 Tyr Phe Glu Asp Pro Leu Gly Pro Glu Ile Glu Glu Tyr Phe Thr Arg 180 185 190 acc gca tgg ctt cgt gaa caa act cgc gat tcc att ctg agc tcc cgc 624 Thr Ala Trp Leu Arg Glu Gln Thr Arg Asp Ser Ile Leu Ser Ser Arg 195 200 205 ttc aaa gtt cgc cct ggc gtg gcc cgg gaa caa atc agc ctg gcc gat 672 Phe Lys Val Arg Pro Gly Val Ala Arg Glu Gln Ile Ser Leu Ala Asp 210 215 220 gcg gaa gaa ggc atg ggc ttt agt cct gtc acg ttg agg ctc acc cgc 720 Ala Glu Glu Gly Met Gly Phe Ser Pro Val Thr Leu Arg Leu Thr Arg 225 230 235 240 acc gat ggt cct cgt tgg tcc cat gat gtt gat gag cat gtg gct tcc 768 Thr Asp Gly Pro Arg Trp Ser His Asp Val Asp Glu His Val Ala Ser 245 250 255 atc gtc gca gga ctt aac cca cat gga ctc ccc ttt gaa gaa atc ctg 816 Ile Val Ala Gly Leu Asn Pro His Gly Leu Pro Phe Glu Glu Ile Leu 260 265 270 gaa atg tac gcg atg gct caa ggt atc gag gga gaa tcc ctg cac aac 864 Glu Met Tyr Ala Met Ala Gln Gly Ile Glu Gly Glu Ser Leu His Asn 275 280 285 ggc gcc att gcg gcg ttg gtg gat ctc atc cgc cac gga ttg gtg ttg 912 Gly Ala Ile Ala Ala Leu Val Asp Leu Ile Arg His Gly Leu Val Leu 290 295 300 ccc gct gat ctt ctc gat tct taaataagga ctgattgtga aag 956 Pro Ala Asp Leu Leu Asp Ser 305 310 <210> 846 <211> 311 <212> PRT <213> Corynebacterium glutamicum <400> 846 Asp Ser Gly Ile Pro Thr Gln Leu Val Glu Gly Ser Trp Phe Glu Pro 1 5 10 15 Val Arg Gly Arg Thr Phe Asp Arg Ile Ile Ala Asn Pro Pro Phe Val 20 25 30 Val Gly Pro Pro Glu Ile Gly His Val Tyr Arg Asp Ser Gly Met Asp 35 40 45 Leu Asp Gly Ala Thr Ala Leu Val Val Lys Glu Ala Cys Ala His Leu 50 55 60 Asn Pro Gly Gly Thr Ala His Leu Leu Gly Ala Trp Val His Ser Ala 65 70 75 80 Asp Gln Ser Trp Gln Gln Arg Val Ala Glu Trp Leu Pro Asp Asn Gly 85 90 95 Tyr Val Ala Trp Val Ile Glu Arg Asp Ala Val Ser Pro Ala Gln Tyr 100 105 110 Val Gly Thr Trp Leu Ser Asp Glu Ser Leu Asp Leu Arg Ser Pro Glu 115 120 125 Ala Ala Ala Arg Thr Thr Ala Trp Leu Asn His Phe Glu Lys Ala Lys 130 135 140 Val Gln Gly Val Gly Phe Gly Phe Ile Ala Ile Gln Arg Leu Glu Glu 145 150 155 160 Asp Glu Ala Asp Glu Lys Ser Asp Ile Leu Ala Glu Ser Met Thr Gln 165 170 175 Tyr Phe Glu Asp Pro Leu Gly Pro Glu Ile Glu Glu Tyr Phe Thr Arg 180 185 190 Thr Ala Trp Leu Arg Glu Gln Thr Arg Asp Ser Ile Leu Ser Ser Arg 195 200 205 Phe Lys Val Arg Pro Gly Val Ala Arg Glu Gln Ile Ser Leu Ala Asp 210 215 220 Ala Glu Glu Gly Met Gly Phe Ser Pro Val Thr Leu Arg Leu Thr Arg 225 230 235 240 Thr Asp Gly Pro Arg Trp Ser His Asp Val Asp Glu His Val Ala Ser 245 250 255 Ile Val Ala Gly Leu Asn Pro His Gly Leu Pro Phe Glu Glu Ile Leu 260 265 270 Glu Met Tyr Ala Met Ala Gln Gly Ile Glu Gly Glu Ser Leu His Asn 275 280 285 Gly Ala Ile Ala Ala Leu Val Asp Leu Ile Arg His Gly Leu Val Leu 290 295 300 Pro Ala Asp Leu Leu Asp Ser 305 310 <210> 847 <211> 819 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(796) <223> RXC01715 <400> 847 acatgttgtt ggaacatgcc ggcagagccg acactacgat tcattcgcta aagggtctgg 60 ccactgacac tggcaaagat ccacgaaagg aagttaccct gtg agc gag ctc gat 115 Val Ser Glu Leu Asp 1 5 att aaa cag ctc aac aaa ctg cag cgc tac tct cag tgg gcg gtg ttc 163 Ile Lys Gln Leu Asn Lys Leu Gln Arg Tyr Ser Gln Trp Ala Val Phe 10 15 20 cgt gct att cct gga gcg ctc gat gat gat cgc aca gaa gtc act gac 211 Arg Ala Ile Pro Gly Ala Leu Asp Asp Asp Arg Thr Glu Val Thr Asp 25 30 35 caa gca gcc aag ttc ttt gcc gac ctt gaa gca gaa ggc aaa gtc act 259 Gln Ala Ala Lys Phe Phe Ala Asp Leu Glu Ala Glu Gly Lys Val Thr 40 45 50 gtc cgt ggc att tac aac gcc tcc ggc ctg cgc gca gac gct gac tac 307 Val Arg Gly Ile Tyr Asn Ala Ser Gly Leu Arg Ala Asp Ala Asp Tyr 55 60 65 atg atc tgg tgg cac gca gaa gaa ttc gaa gac att cag aag gcc ttc 355 Met Ile Trp Trp His Ala Glu Glu Phe Glu Asp Ile Gln Lys Ala Phe 70 75 80 85 gct gat ttc cgc cgc acc acc att ttg ggt cag gtt tct gag gtc ttc 403 Ala Asp Phe Arg Arg Thr Thr Ile Leu Gly Gln Val Ser Glu Val Phe 90 95 100 tgg atc gga aac gct ctc cac cgt cca tct gag ttc aac aag gct cac 451 Trp Ile Gly Asn Ala Leu His Arg Pro Ser Glu Phe Asn Lys Ala His 105 110 115 ttg cct tca ttc atc atg ggt gaa gaa gca aag gac tgg atc act gtt 499 Leu Pro Ser Phe Ile Met Gly Glu Glu Ala Lys Asp Trp Ile Thr Val 120 125 130 tac ccg ttc gtg cgc agc tac gac tgg tac atc atg gag ccc ttg aag 547 Tyr Pro Phe Val Arg Ser Tyr Asp Trp Tyr Ile Met Glu Pro Leu Lys 135 140 145 cgt tcc cgc att ctc cgc gag cac gga caa gct gct gtg gaa ttc cca 595 Arg Ser Arg Ile Leu Arg Glu His Gly Gln Ala Ala Val Glu Phe Pro 150 155 160 165 gat gtt cgt gcc aac act gtg ccg gct ttc gca ctg ggt gac tac gaa 643 Asp Val Arg Ala Asn Thr Val Pro Ala Phe Ala Leu Gly Asp Tyr Glu 170 175 180 tgg gtg ctg gct ttc gag gct gat gag ttg cac cgc att gtc gat ttg 691 Trp Val Leu Ala Phe Glu Ala Asp Glu Leu His Arg Ile Val Asp Leu 185 190 195 atg cac aag atg cgt tac acc gag gct cgc ctc cac gtc cgt gag gag 739 Met His Lys Met Arg Tyr Thr Glu Ala Arg Leu His Val Arg Glu Glu 200 205 210 ctg cca ttt att tct gga cag cgc gtc gac att gca gat ctg att aag 787 Leu Pro Phe Ile Ser Gly Gln Arg Val Asp Ile Ala Asp Leu Ile Lys 215 220 225 gtt ctt cct taaaagctgc ttttctaaac gat 819 Val Leu Pro 230 <210> 848 <211> 232 <212> PRT <213> Corynebacterium glutamicum <400> 848 Val Ser Glu Leu Asp Ile Lys Gln Leu Asn Lys Leu Gln Arg Tyr Ser 1 5 10 15 Gln Trp Ala Val Phe Arg Ala Ile Pro Gly Ala Leu Asp Asp Asp Arg 20 25 30 Thr Glu Val Thr Asp Gln Ala Ala Lys Phe Phe Ala Asp Leu Glu Ala 35 40 45 Glu Gly Lys Val Thr Val Arg Gly Ile Tyr Asn Ala Ser Gly Leu Arg 50 55 60 Ala Asp Ala Asp Tyr Met Ile Trp Trp His Ala Glu Glu Phe Glu Asp 65 70 75 80 Ile Gln Lys Ala Phe Ala Asp Phe Arg Arg Thr Thr Ile Leu Gly Gln 85 90 95 Val Ser Glu Val Phe Trp Ile Gly Asn Ala Leu His Arg Pro Ser Glu 100 105 110 Phe Asn Lys Ala His Leu Pro Ser Phe Ile Met Gly Glu Glu Ala Lys 115 120 125 Asp Trp Ile Thr Val Tyr Pro Phe Val Arg Ser Tyr Asp Trp Tyr Ile 130 135 140 Met Glu Pro Leu Lys Arg Ser Arg Ile Leu Arg Glu His Gly Gln Ala 145 150 155 160 Ala Val Glu Phe Pro Asp Val Arg Ala Asn Thr Val Pro Ala Phe Ala 165 170 175 Leu Gly Asp Tyr Glu Trp Val Leu Ala Phe Glu Ala Asp Glu Leu His 180 185 190 Arg Ile Val Asp Leu Met His Lys Met Arg Tyr Thr Glu Ala Arg Leu 195 200 205 His Val Arg Glu Glu Leu Pro Phe Ile Ser Gly Gln Arg Val Asp Ile 210 215 220 Ala Asp Leu Ile Lys Val Leu Pro 225 230 <210> 849 <211> 1587 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1564) <223> RXN00420 <400> 849 attcgtgaac tcatggatct ttaggcaata aatgtgagat tggacgattt cacgcttgtc 60 ttcaccacct gaaaattttc gggggtaacc tttaaaggcg atg aac agt tct cac 115 Met Asn Ser Ser His 1 5 ggc acg tcc agc tcc ggc gct tcg gcc ggt gcc cac gga gcc ctt ccc 163 Gly Thr Ser Ser Ser Gly Ala Ser Ala Gly Ala His Gly Ala Leu Pro 10 15 20 cta gaa gct cag aaa ctg aac ggt tgg ggc cgc aca gcc ccc acc acc 211 Leu Glu Ala Gln Lys Leu Asn Gly Trp Gly Arg Thr Ala Pro Thr Thr 25 30 35 gct gag gta ctt acc acc cca gac cta gac atc att gtg gat gca gtc 259 Ala Glu Val Leu Thr Thr Pro Asp Leu Asp Ile Ile Val Asp Ala Val 40 45 50 cgc caa gtc gct gaa caa aac gac tcc aag ccg gac tac ctc aag cgc 307 Arg Gln Val Ala Glu Gln Asn Asp Ser Lys Pro Asp Tyr Leu Lys Arg 55 60 65 ggc gtg att gcc cgt ggc atg ggt cgt tcc tat ggt gac cca gcc caa 355 Gly Val Ile Ala Arg Gly Met Gly Arg Ser Tyr Gly Asp Pro Ala Gln 70 75 80 85 aac gcc ggt ggc ctt gtc att gac atg cag cca ctg aac aaa atc cac 403 Asn Ala Gly Gly Leu Val Ile Asp Met Gln Pro Leu Asn Lys Ile His 90 95 100 tcg att gat cct gat tct gcg atc gtc gat gta gat ggc ggc gtc acc 451 Ser Ile Asp Pro Asp Ser Ala Ile Val Asp Val Asp Gly Gly Val Thr 105 110 115 ctc gat cag ctc atg aag gct gcc ctg cca tat ggc ctc tgg gtt cct 499 Leu Asp Gln Leu Met Lys Ala Ala Leu Pro Tyr Gly Leu Trp Val Pro 120 125 130 gtc ctt ccc ggc acc cgc caa gtc acc atc ggt ggc gca atc gga cca 547 Val Leu Pro Gly Thr Arg Gln Val Thr Ile Gly Gly Ala Ile Gly Pro 135 140 145 gac atc cac ggt aag aac cac cac tct gca ggt tcc ttc ggc gac cac 595 Asp Ile His Gly Lys Asn His His Ser Ala Gly Ser Phe Gly Asp His 150 155 160 165 gtg gtc tcc atg gaa ctc ctc gtt gca gac gga cgc atc ctg cac ctc 643 Val Val Ser Met Glu Leu Leu Val Ala Asp Gly Arg Ile Leu His Leu 170 175 180 gag cca gaa ggc acc gcc gaa gac cca cag ggc gac ctg ttc tgg gca 691 Glu Pro Glu Gly Thr Ala Glu Asp Pro Gln Gly Asp Leu Phe Trp Ala 185 190 195 acc gtt ggt ggc atg ggc ctg acc ggc atc atc gtc cgt gca cgc atc 739 Thr Val Gly Gly Met Gly Leu Thr Gly Ile Ile Val Arg Ala Arg Ile 200 205 210 cgc atg acc aag acg gaa acc gcc tac ttc att gcg gac acc gac cgc 787 Arg Met Thr Lys Thr Glu Thr Ala Tyr Phe Ile Ala Asp Thr Asp Arg 215 220 225 acc aac aac ttg gaa gaa acc gtt gcg ttc cac tcc gac gga tca gag 835 Thr Asn Asn Leu Glu Glu Thr Val Ala Phe His Ser Asp Gly Ser Glu 230 235 240 245 cac aac tac acc tat tct tct gcg tgg ttc gat gtc atc agc cct gag 883 His Asn Tyr Thr Tyr Ser Ser Ala Trp Phe Asp Val Ile Ser Pro Glu 250 255 260 cca aag ctt ggc cgc tcc acc atc tcc cgt ggt tcc ctg gca aca ctt 931 Pro Lys Leu Gly Arg Ser Thr Ile Ser Arg Gly Ser Leu Ala Thr Leu 265 270 275 gct cag ctg gaa gaa ttg gca cca aag ctg gcc aag gat cca ctg aag 979 Ala Gln Leu Glu Glu Leu Ala Pro Lys Leu Ala Lys Asp Pro Leu Lys 280 285 290 ttt aat gct cca cag ctg atg aag gtt cca gat atc ttc cca tcc tgg 1027 Phe Asn Ala Pro Gln Leu Met Lys Val Pro Asp Ile Phe Pro Ser Trp 295 300 305 act ttg aac aag ctg acc ctt tcc gca gtc ggt gtg gct tac tac gcc 1075 Thr Leu Asn Lys Leu Thr Leu Ser Ala Val Gly Val Ala Tyr Tyr Ala 310 315 320 325 atg ggt gca cca gcg aaa aac cag gtg aaa aac ctc acc cag ttc tac 1123 Met Gly Ala Pro Ala Lys Asn Gln Val Lys Asn Leu Thr Gln Phe Tyr 330 335 340 caa cca ctg gat ttg atc ggc gaa tgg aac cgt ggc tac ggc tcc aag 1171 Gln Pro Leu Asp Leu Ile Gly Glu Trp Asn Arg Gly Tyr Gly Ser Lys 345 350 355 ggc ttc ctg cag tac cag ttc gtg gtc ccc aca gaa gct gtt gag cct 1219 Gly Phe Leu Gln Tyr Gln Phe Val Val Pro Thr Glu Ala Val Glu Pro 360 365 370 ttc aag gac atc atc cgc gat atg caa aag tcc ggc cac tac tcc gca 1267 Phe Lys Asp Ile Ile Arg Asp Met Gln Lys Ser Gly His Tyr Ser Ala 375 380 385 ctc aac gtg ttc aaa ctg ttt ggc cca ggc aac cgc gca cca ctg tcc 1315 Leu Asn Val Phe Lys Leu Phe Gly Pro Gly Asn Arg Ala Pro Leu Ser 390 395 400 405 tac cca atg cca ggc tgg aac gtc tgc gtt gac ttc cct atc cgc cca 1363 Tyr Pro Met Pro Gly Trp Asn Val Cys Val Asp Phe Pro Ile Arg Pro 410 415 420 ggt ctg gga gct ttc ttg gac gat ctg gac aag cgc gtc atg gaa ttc 1411 Gly Leu Gly Ala Phe Leu Asp Asp Leu Asp Lys Arg Val Met Glu Phe 425 430 435 ggc ggc cgc ctc tac ctg gcc aag gaa tcc cgc acc tcc gca gag aac 1459 Gly Gly Arg Leu Tyr Leu Ala Lys Glu Ser Arg Thr Ser Ala Glu Asn 440 445 450 ttc cac gcc atg tac cca ggt atg gaa ggc tgg ttg aag act cga aat 1507 Phe His Ala Met Tyr Pro Gly Met Glu Gly Trp Leu Lys Thr Arg Asn 455 460 465 gag atc gac cca acc gga gtc ttt gca tct gac atg tcc cgc cga ctt 1555 Glu Ile Asp Pro Thr Gly Val Phe Ala Ser Asp Met Ser Arg Arg Leu 470 475 480 485 gag ctt tct taagaaaggg cttgaactaa aca 1587 Glu Leu Ser <210> 850 <211> 488 <212> PRT <213> Corynebacterium glutamicum <400> 850 Met Asn Ser Ser His Gly Thr Ser Ser Ser Gly Ala Ser Ala Gly Ala 1 5 10 15 His Gly Ala Leu Pro Leu Glu Ala Gln Lys Leu Asn Gly Trp Gly Arg 20 25 30 Thr Ala Pro Thr Thr Ala Glu Val Leu Thr Thr Pro Asp Leu Asp Ile 35 40 45 Ile Val Asp Ala Val Arg Gln Val Ala Glu Gln Asn Asp Ser Lys Pro 50 55 60 Asp Tyr Leu Lys Arg Gly Val Ile Ala Arg Gly Met Gly Arg Ser Tyr 65 70 75 80 Gly Asp Pro Ala Gln Asn Ala Gly Gly Leu Val Ile Asp Met Gln Pro 85 90 95 Leu Asn Lys Ile His Ser Ile Asp Pro Asp Ser Ala Ile Val Asp Val 100 105 110 Asp Gly Gly Val Thr Leu Asp Gln Leu Met Lys Ala Ala Leu Pro Tyr 115 120 125 Gly Leu Trp Val Pro Val Leu Pro Gly Thr Arg Gln Val Thr Ile Gly 130 135 140 Gly Ala Ile Gly Pro Asp Ile His Gly Lys Asn His His Ser Ala Gly 145 150 155 160 Ser Phe Gly Asp His Val Val Ser Met Glu Leu Leu Val Ala Asp Gly 165 170 175 Arg Ile Leu His Leu Glu Pro Glu Gly Thr Ala Glu Asp Pro Gln Gly 180 185 190 Asp Leu Phe Trp Ala Thr Val Gly Gly Met Gly Leu Thr Gly Ile Ile 195 200 205 Val Arg Ala Arg Ile Arg Met Thr Lys Thr Glu Thr Ala Tyr Phe Ile 210 215 220 Ala Asp Thr Asp Arg Thr Asn Asn Leu Glu Glu Thr Val Ala Phe His 225 230 235 240 Ser Asp Gly Ser Glu His Asn Tyr Thr Tyr Ser Ser Ala Trp Phe Asp 245 250 255 Val Ile Ser Pro Glu Pro Lys Leu Gly Arg Ser Thr Ile Ser Arg Gly 260 265 270 Ser Leu Ala Thr Leu Ala Gln Leu Glu Glu Leu Ala Pro Lys Leu Ala 275 280 285 Lys Asp Pro Leu Lys Phe Asn Ala Pro Gln Leu Met Lys Val Pro Asp 290 295 300 Ile Phe Pro Ser Trp Thr Leu Asn Lys Leu Thr Leu Ser Ala Val Gly 305 310 315 320 Val Ala Tyr Tyr Ala Met Gly Ala Pro Ala Lys Asn Gln Val Lys Asn 325 330 335 Leu Thr Gln Phe Tyr Gln Pro Leu Asp Leu Ile Gly Glu Trp Asn Arg 340 345 350 Gly Tyr Gly Ser Lys Gly Phe Leu Gln Tyr Gln Phe Val Val Pro Thr 355 360 365 Glu Ala Val Glu Pro Phe Lys Asp Ile Ile Arg Asp Met Gln Lys Ser 370 375 380 Gly His Tyr Ser Ala Leu Asn Val Phe Lys Leu Phe Gly Pro Gly Asn 385 390 395 400 Arg Ala Pro Leu Ser Tyr Pro Met Pro Gly Trp Asn Val Cys Val Asp 405 410 415 Phe Pro Ile Arg Pro Gly Leu Gly Ala Phe Leu Asp Asp Leu Asp Lys 420 425 430 Arg Val Met Glu Phe Gly Gly Arg Leu Tyr Leu Ala Lys Glu Ser Arg 435 440 445 Thr Ser Ala Glu Asn Phe His Ala Met Tyr Pro Gly Met Glu Gly Trp 450 455 460 Leu Lys Thr Arg Asn Glu Ile Asp Pro Thr Gly Val Phe Ala Ser Asp 465 470 475 480 Met Ser Arg Arg Leu Glu Leu Ser 485 <210> 851 <211> 563 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(540) <223> FRXA00420 <400> 851 tgg act ttg aac aag ctg acc ctt tcc gca gtc ggt gtg gct tac tac 48 Trp Thr Leu Asn Lys Leu Thr Leu Ser Ala Val Gly Val Ala Tyr Tyr 1 5 10 15 gcc atg ggt gca cca gcg aaa aac cag gtg aaa aac ctc acc cag ttc 96 Ala Met Gly Ala Pro Ala Lys Asn Gln Val Lys Asn Leu Thr Gln Phe 20 25 30 tac caa cca ctg gat ttg atc ggc gaa tgg aac cgt ggc tac ggc tcc 144 Tyr Gln Pro Leu Asp Leu Ile Gly Glu Trp Asn Arg Gly Tyr Gly Ser 35 40 45 aag ggc ttc ctg cag tac cag ttc gtg gtc ccc aca gaa gct gtt gag 192 Lys Gly Phe Leu Gln Tyr Gln Phe Val Val Pro Thr Glu Ala Val Glu 50 55 60 cct ttc aag gac atc atc cgc gat atg caa aag tcc ggc cac tac tcc 240 Pro Phe Lys Asp Ile Ile Arg Asp Met Gln Lys Ser Gly His Tyr Ser 65 70 75 80 gca ctc aac gtg ttc aaa ctg ttt ggc cca ggc aac cgc gca cca ctg 288 Ala Leu Asn Val Phe Lys Leu Phe Gly Pro Gly Asn Arg Ala Pro Leu 85 90 95 tcc tac cca atg cca ggc tgg aac gtc tgc gtt gac ttc cct atc cgc 336 Ser Tyr Pro Met Pro Gly Trp Asn Val Cys Val Asp Phe Pro Ile Arg 100 105 110 cca ggt ctg gga gct ttc ttg gac gat ctg gac aag cgc gtc atg gaa 384 Pro Gly Leu Gly Ala Phe Leu Asp Asp Leu Asp Lys Arg Val Met Glu 115 120 125 ttc ggc ggc cgc ctc tac ctg gcc aag gaa tcc cgc acc tcc gca gag 432 Phe Gly Gly Arg Leu Tyr Leu Ala Lys Glu Ser Arg Thr Ser Ala Glu 130 135 140 aac ttc cac gcc atg tac cca ggt atg gaa ggc tgg ttg aag act cga 480 Asn Phe His Ala Met Tyr Pro Gly Met Glu Gly Trp Leu Lys Thr Arg 145 150 155 160 aat gag atc gac cca acc gga gtc ttt gca tct gac atg tcc cgc cga 528 Asn Glu Ile Asp Pro Thr Gly Val Phe Ala Ser Asp Met Ser Arg Arg 165 170 175 ctt gag ctt tct taagaaaggg cttgaactaa aca 563 Leu Glu Leu Ser 180 <210> 852 <211> 180 <212> PRT <213> Corynebacterium glutamicum <400> 852 Trp Thr Leu Asn Lys Leu Thr Leu Ser Ala Val Gly Val Ala Tyr Tyr 1 5 10 15 Ala Met Gly Ala Pro Ala Lys Asn Gln Val Lys Asn Leu Thr Gln Phe 20 25 30 Tyr Gln Pro Leu Asp Leu Ile Gly Glu Trp Asn Arg Gly Tyr Gly Ser 35 40 45 Lys Gly Phe Leu Gln Tyr Gln Phe Val Val Pro Thr Glu Ala Val Glu 50 55 60 Pro Phe Lys Asp Ile Ile Arg Asp Met Gln Lys Ser Gly His Tyr Ser 65 70 75 80 Ala Leu Asn Val Phe Lys Leu Phe Gly Pro Gly Asn Arg Ala Pro Leu 85 90 95 Ser Tyr Pro Met Pro Gly Trp Asn Val Cys Val Asp Phe Pro Ile Arg 100 105 110 Pro Gly Leu Gly Ala Phe Leu Asp Asp Leu Asp Lys Arg Val Met Glu 115 120 125 Phe Gly Gly Arg Leu Tyr Leu Ala Lys Glu Ser Arg Thr Ser Ala Glu 130 135 140 Asn Phe His Ala Met Tyr Pro Gly Met Glu Gly Trp Leu Lys Thr Arg 145 150 155 160 Asn Glu Ile Asp Pro Thr Gly Val Phe Ala Ser Asp Met Ser Arg Arg 165 170 175 Leu Glu Leu Ser 180 <210> 853 <211> 622 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(622) <223> FRXA00426 <400> 853 attcgtgaac tcatggatct ttaggcaata aatgtgagat tggacgattt cacgcttgtc 60 ttcaccacct gaaaattttc gggggtaacc tttaaaggcg atg aac agt tct cac 115 Met Asn Ser Ser His 1 5 ggc acg tcc agc tcc ggc gct tcg gcc ggt gcc cac gga gcc ctt ccc 163 Gly Thr Ser Ser Ser Gly Ala Ser Ala Gly Ala His Gly Ala Leu Pro 10 15 20 cta gaa gct cag aaa ctg aac ggt tgg ggc cgc aca gcc ccc acc acc 211 Leu Glu Ala Gln Lys Leu Asn Gly Trp Gly Arg Thr Ala Pro Thr Thr 25 30 35 gct gag gta ctt acc acc cca gac cta gac atc att gtg gat gca gtc 259 Ala Glu Val Leu Thr Thr Pro Asp Leu Asp Ile Ile Val Asp Ala Val 40 45 50 cgc caa gtc gct gaa caa aac gac tcc aag ccg gac tac ctc aag cgc 307 Arg Gln Val Ala Glu Gln Asn Asp Ser Lys Pro Asp Tyr Leu Lys Arg 55 60 65 ggc gtg att gcc cgt ggc atg ggt cgt tcc tat ggt gac cca gcc caa 355 Gly Val Ile Ala Arg Gly Met Gly Arg Ser Tyr Gly Asp Pro Ala Gln 70 75 80 85 aac gcc ggt ggc ctt gtc att gac atg cag cca ctg aac aaa atc cac 403 Asn Ala Gly Gly Leu Val Ile Asp Met Gln Pro Leu Asn Lys Ile His 90 95 100 tcg att gat cct gat tct gcg atc gtc gat gta gat ggc ggc gtc acc 451 Ser Ile Asp Pro Asp Ser Ala Ile Val Asp Val Asp Gly Gly Val Thr 105 110 115 ctc gat cag ctc atg aag gct gcc ctg cca tat ggc ctc tgg gtt cct 499 Leu Asp Gln Leu Met Lys Ala Ala Leu Pro Tyr Gly Leu Trp Val Pro 120 125 130 gtc ctt ccc ggc acc cgc caa gtc acc atc ggt ggc gca atc gga cca 547 Val Leu Pro Gly Thr Arg Gln Val Thr Ile Gly Gly Ala Ile Gly Pro 135 140 145 gac atc cac ggt aag aac cac cac tct gca ggt tcc ttc ggc gac cac 595 Asp Ile His Gly Lys Asn His His Ser Ala Gly Ser Phe Gly Asp His 150 155 160 165 gtg gtc tcc atg gaa ctc ctc gtt gca 622 Val Val Ser Met Glu Leu Leu Val Ala 170 <210> 854 <211> 174 <212> PRT <213> Corynebacterium glutamicum <400> 854 Met Asn Ser Ser His Gly Thr Ser Ser Ser Gly Ala Ser Ala Gly Ala 1 5 10 15 His Gly Ala Leu Pro Leu Glu Ala Gln Lys Leu Asn Gly Trp Gly Arg 20 25 30 Thr Ala Pro Thr Thr Ala Glu Val Leu Thr Thr Pro Asp Leu Asp Ile 35 40 45 Ile Val Asp Ala Val Arg Gln Val Ala Glu Gln Asn Asp Ser Lys Pro 50 55 60 Asp Tyr Leu Lys Arg Gly Val Ile Ala Arg Gly Met Gly Arg Ser Tyr 65 70 75 80 Gly Asp Pro Ala Gln Asn Ala Gly Gly Leu Val Ile Asp Met Gln Pro 85 90 95 Leu Asn Lys Ile His Ser Ile Asp Pro Asp Ser Ala Ile Val Asp Val 100 105 110 Asp Gly Gly Val Thr Leu Asp Gln Leu Met Lys Ala Ala Leu Pro Tyr 115 120 125 Gly Leu Trp Val Pro Val Leu Pro Gly Thr Arg Gln Val Thr Ile Gly 130 135 140 Gly Ala Ile Gly Pro Asp Ile His Gly Lys Asn His His Ser Ala Gly 145 150 155 160 Ser Phe Gly Asp His Val Val Ser Met Glu Leu Leu Val Ala 165 170 <210> 855 <211> 930 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(907) <223> RXN00708 <400> 855 cctgcgtatc ggctgccttt ttgaattctt ttcctcctcg aggcctaacc ttcaattcct 60 taccgatccc cttccctgaa gtttcgctaa cctggcgtac atg act ctt tcc ctt 115 Met Thr Leu Ser Leu 1 5 cct cca att ggt ttc ggc acc gtt cat ctt gat ggc gca cct ggc gtt 163 Pro Pro Ile Gly Phe Gly Thr Val His Leu Asp Gly Ala Pro Gly Val 10 15 20 gaa gcc atc gct act gcc att gat gct ggt tac cgc ctc atc gac acc 211 Glu Ala Ile Ala Thr Ala Ile Asp Ala Gly Tyr Arg Leu Ile Asp Thr 25 30 35 gcg tac aac tat gaa aat gaa ggt acc gtg ggc aag gct gtc cgc gag 259 Ala Tyr Asn Tyr Glu Asn Glu Gly Thr Val Gly Lys Ala Val Arg Glu 40 45 50 tcg ggt gtc ccc cgc gag gaa ttg att gtt acc agt aag ctc cct ggc 307 Ser Gly Val Pro Arg Glu Glu Leu Ile Val Thr Ser Lys Leu Pro Gly 55 60 65 cgc ttc cat gct cgc gat cta gga cgc gtc cgc att gag gaa agt cta 355 Arg Phe His Ala Arg Asp Leu Gly Arg Val Arg Ile Glu Glu Ser Leu 70 75 80 85 tac cgc ctc aac tta gat tac atc gat ctc ctc ttg att cac tgg cct 403 Tyr Arg Leu Asn Leu Asp Tyr Ile Asp Leu Leu Leu Ile His Trp Pro 90 95 100 aat ccc agc aag gat ctc tac gtc gag gcg tgg gaa acg ctg att gaa 451 Asn Pro Ser Lys Asp Leu Tyr Val Glu Ala Trp Glu Thr Leu Ile Glu 105 110 115 gtc cgc gat gct ggc ctg gtc aag cac atc gga gtg tct aac ttc ctt 499 Val Arg Asp Ala Gly Leu Val Lys His Ile Gly Val Ser Asn Phe Leu 120 125 130 cca aat cac att gat cgc ctg cgc cgc gaa acc ggt gaa ctg ccg gcc 547 Pro Asn His Ile Asp Arg Leu Arg Arg Glu Thr Gly Glu Leu Pro Ala 135 140 145 gtt aac cag atc gag ttg cac ccc tat ttc ccg cag gtg gag cag gta 595 Val Asn Gln Ile Glu Leu His Pro Tyr Phe Pro Gln Val Glu Gln Val 150 155 160 165 gat ttc cac gat gag ctg ggc atc att acc gag gcc tgg agc ccg ctc 643 Asp Phe His Asp Glu Leu Gly Ile Ile Thr Glu Ala Trp Ser Pro Leu 170 175 180 agc aac ggt cgc gga ctc gtc gaa gag cca ttg ctc aag gaa atc ggc 691 Ser Asn Gly Arg Gly Leu Val Glu Glu Pro Leu Leu Lys Glu Ile Gly 185 190 195 gag cgc tac ggg gtc ggc agc ggc gaa atc gcc ctc gct tgg cat cac 739 Glu Arg Tyr Gly Val Gly Ser Gly Glu Ile Ala Leu Ala Trp His His 200 205 210 gcc agg gga atc gtt ccg att cca cgc tcc acc aac ccg gcc agg cag 787 Ala Arg Gly Ile Val Pro Ile Pro Arg Ser Thr Asn Pro Ala Arg Gln 215 220 225 cgc agc aac ttg gag gcg gta aag att tcg ctt atc gac gaa gac gtc 835 Arg Ser Asn Leu Glu Ala Val Lys Ile Ser Leu Ile Asp Glu Asp Val 230 235 240 245 cag gcg att acc gct ttg gcg cgc aaa aac ggc cgg atc aaa gat caa 883 Gln Ala Ile Thr Ala Leu Ala Arg Lys Asn Gly Arg Ile Lys Asp Gln 250 255 260 gat cca gcc gtc tat gaa gaa ttc tagatagtta catcaaggtt ccg 930 Asp Pro Ala Val Tyr Glu Glu Phe 265 <210> 856 <211> 269 <212> PRT <213> Corynebacterium glutamicum <400> 856 Met Thr Leu Ser Leu Pro Pro Ile Gly Phe Gly Thr Val His Leu Asp 1 5 10 15 Gly Ala Pro Gly Val Glu Ala Ile Ala Thr Ala Ile Asp Ala Gly Tyr 20 25 30 Arg Leu Ile Asp Thr Ala Tyr Asn Tyr Glu Asn Glu Gly Thr Val Gly 35 40 45 Lys Ala Val Arg Glu Ser Gly Val Pro Arg Glu Glu Leu Ile Val Thr 50 55 60 Ser Lys Leu Pro Gly Arg Phe His Ala Arg Asp Leu Gly Arg Val Arg 65 70 75 80 Ile Glu Glu Ser Leu Tyr Arg Leu Asn Leu Asp Tyr Ile Asp Leu Leu 85 90 95 Leu Ile His Trp Pro Asn Pro Ser Lys Asp Leu Tyr Val Glu Ala Trp 100 105 110 Glu Thr Leu Ile Glu Val Arg Asp Ala Gly Leu Val Lys His Ile Gly 115 120 125 Val Ser Asn Phe Leu Pro Asn His Ile Asp Arg Leu Arg Arg Glu Thr 130 135 140 Gly Glu Leu Pro Ala Val Asn Gln Ile Glu Leu His Pro Tyr Phe Pro 145 150 155 160 Gln Val Glu Gln Val Asp Phe His Asp Glu Leu Gly Ile Ile Thr Glu 165 170 175 Ala Trp Ser Pro Leu Ser Asn Gly Arg Gly Leu Val Glu Glu Pro Leu 180 185 190 Leu Lys Glu Ile Gly Glu Arg Tyr Gly Val Gly Ser Gly Glu Ile Ala 195 200 205 Leu Ala Trp His His Ala Arg Gly Ile Val Pro Ile Pro Arg Ser Thr 210 215 220 Asn Pro Ala Arg Gln Arg Ser Asn Leu Glu Ala Val Lys Ile Ser Leu 225 230 235 240 Ile Asp Glu Asp Val Gln Ala Ile Thr Ala Leu Ala Arg Lys Asn Gly 245 250 255 Arg Ile Lys Asp Gln Asp Pro Ala Val Tyr Glu Glu Phe 260 265 <210> 857 <211> 695 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(672) <223> FRXA00708 <400> 857 acc gtg ggc aag gct gtc cgc gag tcg ggt gtc ccc cgc gag gaa ttg 48 Thr Val Gly Lys Ala Val Arg Glu Ser Gly Val Pro Arg Glu Glu Leu 1 5 10 15 att gtt acc agt aag ctc cct ggc cgc ttc cat gct cgc gat cta gga 96 Ile Val Thr Ser Lys Leu Pro Gly Arg Phe His Ala Arg Asp Leu Gly 20 25 30 cgc gtc cgc att gag gaa agt cta tac cgc ctc aac tta gat tac atc 144 Arg Val Arg Ile Glu Glu Ser Leu Tyr Arg Leu Asn Leu Asp Tyr Ile 35 40 45 gat ctc ctc ttg att cac tgg cct aat ccc agc aag gat ctc tac gtc 192 Asp Leu Leu Leu Ile His Trp Pro Asn Pro Ser Lys Asp Leu Tyr Val 50 55 60 gag gcg tgg gaa acg ctg att gaa gtc cgc gat gct ggc ctg gtc aag 240 Glu Ala Trp Glu Thr Leu Ile Glu Val Arg Asp Ala Gly Leu Val Lys 65 70 75 80 cac atc gga gtg tct aac ttc ctt cca aat cac att gat cgc ctg cgc 288 His Ile Gly Val Ser Asn Phe Leu Pro Asn His Ile Asp Arg Leu Arg 85 90 95 cgc gaa acc ggt gaa ctg ccg gcc gtt aac cag atc gag ttg cac ccc 336 Arg Glu Thr Gly Glu Leu Pro Ala Val Asn Gln Ile Glu Leu His Pro 100 105 110 tat ttc ccg cag gtg gag cag gta gat ttc cac gat gag ctg ggc atc 384 Tyr Phe Pro Gln Val Glu Gln Val Asp Phe His Asp Glu Leu Gly Ile 115 120 125 att acc gag gcc tgg agc ccg ctc agc aac ggt cgc gga ctc gtc gaa 432 Ile Thr Glu Ala Trp Ser Pro Leu Ser Asn Gly Arg Gly Leu Val Glu 130 135 140 gag cca ttg ctc aag gaa atc ggc gag cgc tac ggg gtc ggc agc ggc 480 Glu Pro Leu Leu Lys Glu Ile Gly Glu Arg Tyr Gly Val Gly Ser Gly 145 150 155 160 gaa atc gcc ctc gct tgg cat cac gcc agg gga atc gtt ccg att cca 528 Glu Ile Ala Leu Ala Trp His His Ala Arg Gly Ile Val Pro Ile Pro 165 170 175 cgc tcc acc aac ccg gcc agg cag cgc agc aac ttg gag gcg gta aag 576 Arg Ser Thr Asn Pro Ala Arg Gln Arg Ser Asn Leu Glu Ala Val Lys 180 185 190 att tcg ctt atc gac gaa gac gtc cag gcg att acc gct ttg gcg cgc 624 Ile Ser Leu Ile Asp Glu Asp Val Gln Ala Ile Thr Ala Leu Ala Arg 195 200 205 aaa aac ggc cgg atc aaa gat caa gat cca gcc gtc tat gaa gaa ttc 672 Lys Asn Gly Arg Ile Lys Asp Gln Asp Pro Ala Val Tyr Glu Glu Phe 210 215 220 tagatagtta catcaaggtt ccg 695 <210> 858 <211> 224 <212> PRT <213> Corynebacterium glutamicum <400> 858 Thr Val Gly Lys Ala Val Arg Glu Ser Gly Val Pro Arg Glu Glu Leu 1 5 10 15 Ile Val Thr Ser Lys Leu Pro Gly Arg Phe His Ala Arg Asp Leu Gly 20 25 30 Arg Val Arg Ile Glu Glu Ser Leu Tyr Arg Leu Asn Leu Asp Tyr Ile 35 40 45 Asp Leu Leu Leu Ile His Trp Pro Asn Pro Ser Lys Asp Leu Tyr Val 50 55 60 Glu Ala Trp Glu Thr Leu Ile Glu Val Arg Asp Ala Gly Leu Val Lys 65 70 75 80 His Ile Gly Val Ser Asn Phe Leu Pro Asn His Ile Asp Arg Leu Arg 85 90 95 Arg Glu Thr Gly Glu Leu Pro Ala Val Asn Gln Ile Glu Leu His Pro 100 105 110 Tyr Phe Pro Gln Val Glu Gln Val Asp Phe His Asp Glu Leu Gly Ile 115 120 125 Ile Thr Glu Ala Trp Ser Pro Leu Ser Asn Gly Arg Gly Leu Val Glu 130 135 140 Glu Pro Leu Leu Lys Glu Ile Gly Glu Arg Tyr Gly Val Gly Ser Gly 145 150 155 160 Glu Ile Ala Leu Ala Trp His His Ala Arg Gly Ile Val Pro Ile Pro 165 170 175 Arg Ser Thr Asn Pro Ala Arg Gln Arg Ser Asn Leu Glu Ala Val Lys 180 185 190 Ile Ser Leu Ile Asp Glu Asp Val Gln Ala Ile Thr Ala Leu Ala Arg 195 200 205 Lys Asn Gly Arg Ile Lys Asp Gln Asp Pro Ala Val Tyr Glu Glu Phe 210 215 220 <210> 859 <211> 1038 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1015) <223> RXA02373 <400> 859 aaagtcatag ctcatggtaa ttcagtgtag ataggcgtac ggtgggctat ccaattcatc 60 tcaacctaag gcgcattttg gtgcgcatca aggagaaaat atg tct gtt gtg ggt 115 Met Ser Val Val Gly 1 5 acc ggc cta ttc ttt gga tcc ccg gag gaa gag cgg gat aag ttg atg 163 Thr Gly Leu Phe Phe Gly Ser Pro Glu Glu Glu Arg Asp Lys Leu Met 10 15 20 caa tct ttg atg gat cag aag aat aag ctt tcg aag tct gaa ggt atc 211 Gln Ser Leu Met Asp Gln Lys Asn Lys Leu Ser Lys Ser Glu Gly Ile 25 30 35 cca ttg gtc acc ttg aat gat gga aaa acc att cct cag ctt ggt ttt 259 Pro Leu Val Thr Leu Asn Asp Gly Lys Thr Ile Pro Gln Leu Gly Phe 40 45 50 ggt gtg ttc aag gta gat ccc gat gaa gca gag cgc gta gtt acc gaa 307 Gly Val Phe Lys Val Asp Pro Asp Glu Ala Glu Arg Val Val Thr Glu 55 60 65 gca ctt gag gta ggt tac cgc cac atc gat act gct gcg att tac ggc 355 Ala Leu Glu Val Gly Tyr Arg His Ile Asp Thr Ala Ala Ile Tyr Gly 70 75 80 85 aat gag gaa ggt gtc ggc cga gct att gct aag tcc ggc att cct cgt 403 Asn Glu Glu Gly Val Gly Arg Ala Ile Ala Lys Ser Gly Ile Pro Arg 90 95 100 gaa gag ctg ttt att act acc aag ttg tgg aac gat cgc cac ctg gat 451 Glu Glu Leu Phe Ile Thr Thr Lys Leu Trp Asn Asp Arg His Leu Asp 105 110 115 gta gaa gct gct ttt gag gag tct ctg cag aag ctg ggc ttg gat tat 499 Val Glu Ala Ala Phe Glu Glu Ser Leu Gln Lys Leu Gly Leu Asp Tyr 120 125 130 gta gat ctg tac ttg gtg cac tgg ccg gca ccg aag aac gat aat tat 547 Val Asp Leu Tyr Leu Val His Trp Pro Ala Pro Lys Asn Asp Asn Tyr 135 140 145 gtt gct gca tgg aag ggc ttg gaa aag ctc ggt gac cgt gct cgt tcc 595 Val Ala Ala Trp Lys Gly Leu Glu Lys Leu Gly Asp Arg Ala Arg Ser 150 155 160 165 atc ggt gtg tgc aac ttc ctg cca gag cac cta gaa aag ctg ctg gca 643 Ile Gly Val Cys Asn Phe Leu Pro Glu His Leu Glu Lys Leu Leu Ala 170 175 180 gag gca acc act gtg cct gcc att aac cag att gag ctg cac cca gct 691 Glu Ala Thr Thr Val Pro Ala Ile Asn Gln Ile Glu Leu His Pro Ala 185 190 195 ttg cag cag cgc gat gct gtt gag gca tct ctt gca gca ggc atc act 739 Leu Gln Gln Arg Asp Ala Val Glu Ala Ser Leu Ala Ala Gly Ile Thr 200 205 210 gtg gag tcg tgg ggt cct ctg gga cag ggg cgt ttt gat ctt ggc gct 787 Val Glu Ser Trp Gly Pro Leu Gly Gln Gly Arg Phe Asp Leu Gly Ala 215 220 225 gag gaa cca atc gca gct gca gcg aag aac cat gga aag acc cca gct 835 Glu Glu Pro Ile Ala Ala Ala Ala Lys Asn His Gly Lys Thr Pro Ala 230 235 240 245 cag gtt gtt atc cgt tgg cac ctg cag aac ggt ttc gtt gtg ttc ccc 883 Gln Val Val Ile Arg Trp His Leu Gln Asn Gly Phe Val Val Phe Pro 250 255 260 aag act gtg act aag agc cgc atg gtg gaa aac atc gac gtg ttt gat 931 Lys Thr Val Thr Lys Ser Arg Met Val Glu Asn Ile Asp Val Phe Asp 265 270 275 ttc gaa ctc agt gat gag gag atg gct gcg atc act gct ctt gag cgc 979 Phe Glu Leu Ser Asp Glu Glu Met Ala Ala Ile Thr Ala Leu Glu Arg 280 285 290 aat gat cgt ggt ggt tca cac ccg aat gat ctg aac tagaaataag 1025 Asn Asp Arg Gly Gly Ser His Pro Asn Asp Leu Asn 295 300 305 gtaaggccct gca 1038 <210> 860 <211> 305 <212> PRT <213> Corynebacterium glutamicum <400> 860 Met Ser Val Val Gly Thr Gly Leu Phe Phe Gly Ser Pro Glu Glu Glu 1 5 10 15 Arg Asp Lys Leu Met Gln Ser Leu Met Asp Gln Lys Asn Lys Leu Ser 20 25 30 Lys Ser Glu Gly Ile Pro Leu Val Thr Leu Asn Asp Gly Lys Thr Ile 35 40 45 Pro Gln Leu Gly Phe Gly Val Phe Lys Val Asp Pro Asp Glu Ala Glu 50 55 60 Arg Val Val Thr Glu Ala Leu Glu Val Gly Tyr Arg His Ile Asp Thr 65 70 75 80 Ala Ala Ile Tyr Gly Asn Glu Glu Gly Val Gly Arg Ala Ile Ala Lys 85 90 95 Ser Gly Ile Pro Arg Glu Glu Leu Phe Ile Thr Thr Lys Leu Trp Asn 100 105 110 Asp Arg His Leu Asp Val Glu Ala Ala Phe Glu Glu Ser Leu Gln Lys 115 120 125 Leu Gly Leu Asp Tyr Val Asp Leu Tyr Leu Val His Trp Pro Ala Pro 130 135 140 Lys Asn Asp Asn Tyr Val Ala Ala Trp Lys Gly Leu Glu Lys Leu Gly 145 150 155 160 Asp Arg Ala Arg Ser Ile Gly Val Cys Asn Phe Leu Pro Glu His Leu 165 170 175 Glu Lys Leu Leu Ala Glu Ala Thr Thr Val Pro Ala Ile Asn Gln Ile 180 185 190 Glu Leu His Pro Ala Leu Gln Gln Arg Asp Ala Val Glu Ala Ser Leu 195 200 205 Ala Ala Gly Ile Thr Val Glu Ser Trp Gly Pro Leu Gly Gln Gly Arg 210 215 220 Phe Asp Leu Gly Ala Glu Glu Pro Ile Ala Ala Ala Ala Lys Asn His 225 230 235 240 Gly Lys Thr Pro Ala Gln Val Val Ile Arg Trp His Leu Gln Asn Gly 245 250 255 Phe Val Val Phe Pro Lys Thr Val Thr Lys Ser Arg Met Val Glu Asn 260 265 270 Ile Asp Val Phe Asp Phe Glu Leu Ser Asp Glu Glu Met Ala Ala Ile 275 280 285 Thr Ala Leu Glu Arg Asn Asp Arg Gly Gly Ser His Pro Asn Asp Leu 290 295 300 Asn 305 <210> 861 <211> 1683 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1660) <223> RXS00389 <400> 861 ccaccactgc gtaacctttc cgagcaagat atcgcggacc tgtcggattt gcttgccacc 60 tctggcgcag gttcctaccg ccttcagttg aggtgaaagc atg atc acc gca acc 115 Met Ile Thr Ala Thr 1 5 gca ctg cat ggg tgt tca ctg att gat ggc gag tgg gtc gct gga aaa 163 Ala Leu His Gly Cys Ser Leu Ile Asp Gly Glu Trp Val Ala Gly Lys 10 15 20 aat ggt gag att aca gga ttc gat ccg cgc acc aat gcg agt ctg aac 211 Asn Gly Glu Ile Thr Gly Phe Asp Pro Arg Thr Asn Ala Ser Leu Asn 25 30 35 cct tcc tac tct tta gca aac agc gca cag ctg cgc gcc gcc aca aca 259 Pro Ser Tyr Ser Leu Ala Asn Ser Ala Gln Leu Arg Ala Ala Thr Thr 40 45 50 tcg gcg aag cga gct ttt gaa agc tac cga ctc act act cca gag gtt 307 Ser Ala Lys Arg Ala Phe Glu Ser Tyr Arg Leu Thr Thr Pro Glu Val 55 60 65 aga gca gat ttc ctg gat tcc atc gct gac aac atc gat gcg cta tcc 355 Arg Ala Asp Phe Leu Asp Ser Ile Ala Asp Asn Ile Asp Ala Leu Ser 70 75 80 85 ggc gag atc gtg caa cgg gcg agc ctg gag aca ggt ttg gga act acc 403 Gly Glu Ile Val Gln Arg Ala Ser Leu Glu Thr Gly Leu Gly Thr Thr 90 95 100 cga ctc aca ggc gaa gta gcc cgc acc agc aac cag ctc cgc ctg ttt 451 Arg Leu Thr Gly Glu Val Ala Arg Thr Ser Asn Gln Leu Arg Leu Phe 105 110 115 gca gaa acc gtg aga agc gga cag ttc cac cga gta cgc att gaa cga 499 Ala Glu Thr Val Arg Ser Gly Gln Phe His Arg Val Arg Ile Glu Arg 120 125 130 gga ccg cgg att gat ctt cgc cag cgt cag gtt ccg ttg gga cca gtc 547 Gly Pro Arg Ile Asp Leu Arg Gln Arg Gln Val Pro Leu Gly Pro Val 135 140 145 gcg gta ttc ggg gca agc aac ttc ccc gtc gct ttc tct act gct ggt 595 Ala Val Phe Gly Ala Ser Asn Phe Pro Val Ala Phe Ser Thr Ala Gly 150 155 160 165 ggc gat aca gca tca gcg ttg gct gca ggc tgc cct gtg gtt ttt aag 643 Gly Asp Thr Ala Ser Ala Leu Ala Ala Gly Cys Pro Val Val Phe Lys 170 175 180 gcg cat aat gcg cac cct gga aca gct gag ctc gtc ggg caa gcg gtg 691 Ala His Asn Ala His Pro Gly Thr Ala Glu Leu Val Gly Gln Ala Val 185 190 195 cgg gga gcc gtc gaa aag cat gag ttt gat gct ggt gtg ttt aac ctt 739 Arg Gly Ala Val Glu Lys His Glu Phe Asp Ala Gly Val Phe Asn Leu 200 205 210 gtc tac ggc cgt ggc gtg gaa att ggc cag gag ctg gct gcg gat ccg 787 Val Tyr Gly Arg Gly Val Glu Ile Gly Gln Glu Leu Ala Ala Asp Pro 215 220 225 aat atc acg gca atc ggt ttt acc ggt tca cgc cag ggt ggt ttg gca 835 Asn Ile Thr Ala Ile Gly Phe Thr Gly Ser Arg Gln Gly Gly Leu Ala 230 235 240 245 ctg tca cag act gcg ttt agc cgc cca gtt ccc gtt cca gtc ttt gca 883 Leu Ser Gln Thr Ala Phe Ser Arg Pro Val Pro Val Pro Val Phe Ala 250 255 260 gaa atg agt gcc acc aac cct gtg ttc gtc ttc ccc ggc gcg ctg gcg 931 Glu Met Ser Ala Thr Asn Pro Val Phe Val Phe Pro Gly Ala Leu Ala 265 270 275 gat ttg gat gca tcg agt tcc ttg gct gag gcg ttt acc gct tcc gtc 979 Asp Leu Asp Ala Ser Ser Ser Leu Ala Glu Ala Phe Thr Ala Ser Val 280 285 290 acc ggc agt tcc ggg caa ttg tgc acc aag cct ggc ctc gtt ttc atc 1027 Thr Gly Ser Ser Gly Gln Leu Cys Thr Lys Pro Gly Leu Val Phe Ile 295 300 305 ccg cgc ggt gtt gtt ggt gat gct ttt gtg gcg ctc gta gca gcc aaa 1075 Pro Arg Gly Val Val Gly Asp Ala Phe Val Ala Leu Val Ala Ala Lys 310 315 320 325 ttt aaa gaa acc acg ggt caa acg atg ctc acg caa ggc atc gct cag 1123 Phe Lys Glu Thr Thr Gly Gln Thr Met Leu Thr Gln Gly Ile Ala Gln 330 335 340 gca tgg cag cgc gga gtc gac aac ctt gca gca cag cca agt gta aaa 1171 Ala Trp Gln Arg Gly Val Asp Asn Leu Ala Ala Gln Pro Ser Val Lys 345 350 355 atc ctc gcc caa ggc acc ccc gga gat gga gag aac gcg ccg ggc ccg 1219 Ile Leu Ala Gln Gly Thr Pro Gly Asp Gly Glu Asn Ala Pro Gly Pro 360 365 370 gtg gtg ttt gaa agt gat gtg cag gcg ttg cta aat aat gtg gtg ttg 1267 Val Val Phe Glu Ser Asp Val Gln Ala Leu Leu Asn Asn Val Val Leu 375 380 385 cag gaa gaa atc ttc ggt gcg gca tcg ctg gtg gtg cgt tat gat tcc 1315 Gln Glu Glu Ile Phe Gly Ala Ala Ser Leu Val Val Arg Tyr Asp Ser 390 395 400 405 ccg gat caa ctc cac caa gta gcc aat tca ctc gag gga caa tta aca 1363 Pro Asp Gln Leu His Gln Val Ala Asn Ser Leu Glu Gly Gln Leu Thr 410 415 420 gcc acg atc cac gca tcc cag gat gat ttc cag gaa gtc tcg aaa ctt 1411 Ala Thr Ile His Ala Ser Gln Asp Asp Phe Gln Glu Val Ser Lys Leu 425 430 435 atc ccc ctc ttg gag gat ctc gcg ggc cgt gtt ctt tac ggc ggc tgg 1459 Ile Pro Leu Leu Glu Asp Leu Ala Gly Arg Val Leu Tyr Gly Gly Trp 440 445 450 cca acg ggt gtg gaa gtt ggg cac acg gtt atc cat gga ggc cct tat 1507 Pro Thr Gly Val Glu Val Gly His Thr Val Ile His Gly Gly Pro Tyr 455 460 465 ccg gcg acc tca aat gcg cag tcg aca agt gtt gga acc ctg gca atc 1555 Pro Ala Thr Ser Asn Ala Gln Ser Thr Ser Val Gly Thr Leu Ala Ile 470 475 480 485 gag aga ttt atg cgc ccg gtt tct tat caa act ttc ccg gct gag ctg 1603 Glu Arg Phe Met Arg Pro Val Ser Tyr Gln Thr Phe Pro Ala Glu Leu 490 495 500 ctt cca gat cca gtt tct gag gcg aat aaa tgg gct gta cct cgg gaa 1651 Leu Pro Asp Pro Val Ser Glu Ala Asn Lys Trp Ala Val Pro Arg Glu 505 510 515 ata gac cgt taatagctgg tctttacatt tgc 1683 Ile Asp Arg 520 <210> 862 <211> 520 <212> PRT <213> Corynebacterium glutamicum <400> 862 Met Ile Thr Ala Thr Ala Leu His Gly Cys Ser Leu Ile Asp Gly Glu 1 5 10 15 Trp Val Ala Gly Lys Asn Gly Glu Ile Thr Gly Phe Asp Pro Arg Thr 20 25 30 Asn Ala Ser Leu Asn Pro Ser Tyr Ser Leu Ala Asn Ser Ala Gln Leu 35 40 45 Arg Ala Ala Thr Thr Ser Ala Lys Arg Ala Phe Glu Ser Tyr Arg Leu 50 55 60 Thr Thr Pro Glu Val Arg Ala Asp Phe Leu Asp Ser Ile Ala Asp Asn 65 70 75 80 Ile Asp Ala Leu Ser Gly Glu Ile Val Gln Arg Ala Ser Leu Glu Thr 85 90 95 Gly Leu Gly Thr Thr Arg Leu Thr Gly Glu Val Ala Arg Thr Ser Asn 100 105 110 Gln Leu Arg Leu Phe Ala Glu Thr Val Arg Ser Gly Gln Phe His Arg 115 120 125 Val Arg Ile Glu Arg Gly Pro Arg Ile Asp Leu Arg Gln Arg Gln Val 130 135 140 Pro Leu Gly Pro Val Ala Val Phe Gly Ala Ser Asn Phe Pro Val Ala 145 150 155 160 Phe Ser Thr Ala Gly Gly Asp Thr Ala Ser Ala Leu Ala Ala Gly Cys 165 170 175 Pro Val Val Phe Lys Ala His Asn Ala His Pro Gly Thr Ala Glu Leu 180 185 190 Val Gly Gln Ala Val Arg Gly Ala Val Glu Lys His Glu Phe Asp Ala 195 200 205 Gly Val Phe Asn Leu Val Tyr Gly Arg Gly Val Glu Ile Gly Gln Glu 210 215 220 Leu Ala Ala Asp Pro Asn Ile Thr Ala Ile Gly Phe Thr Gly Ser Arg 225 230 235 240 Gln Gly Gly Leu Ala Leu Ser Gln Thr Ala Phe Ser Arg Pro Val Pro 245 250 255 Val Pro Val Phe Ala Glu Met Ser Ala Thr Asn Pro Val Phe Val Phe 260 265 270 Pro Gly Ala Leu Ala Asp Leu Asp Ala Ser Ser Ser Leu Ala Glu Ala 275 280 285 Phe Thr Ala Ser Val Thr Gly Ser Ser Gly Gln Leu Cys Thr Lys Pro 290 295 300 Gly Leu Val Phe Ile Pro Arg Gly Val Val Gly Asp Ala Phe Val Ala 305 310 315 320 Leu Val Ala Ala Lys Phe Lys Glu Thr Thr Gly Gln Thr Met Leu Thr 325 330 335 Gln Gly Ile Ala Gln Ala Trp Gln Arg Gly Val Asp Asn Leu Ala Ala 340 345 350 Gln Pro Ser Val Lys Ile Leu Ala Gln Gly Thr Pro Gly Asp Gly Glu 355 360 365 Asn Ala Pro Gly Pro Val Val Phe Glu Ser Asp Val Gln Ala Leu Leu 370 375 380 Asn Asn Val Val Leu Gln Glu Glu Ile Phe Gly Ala Ala Ser Leu Val 385 390 395 400 Val Arg Tyr Asp Ser Pro Asp Gln Leu His Gln Val Ala Asn Ser Leu 405 410 415 Glu Gly Gln Leu Thr Ala Thr Ile His Ala Ser Gln Asp Asp Phe Gln 420 425 430 Glu Val Ser Lys Leu Ile Pro Leu Leu Glu Asp Leu Ala Gly Arg Val 435 440 445 Leu Tyr Gly Gly Trp Pro Thr Gly Val Glu Val Gly His Thr Val Ile 450 455 460 His Gly Gly Pro Tyr Pro Ala Thr Ser Asn Ala Gln Ser Thr Ser Val 465 470 475 480 Gly Thr Leu Ala Ile Glu Arg Phe Met Arg Pro Val Ser Tyr Gln Thr 485 490 495 Phe Pro Ala Glu Leu Leu Pro Asp Pro Val Ser Glu Ala Asn Lys Trp 500 505 510 Ala Val Pro Arg Glu Ile Asp Arg 515 520 <210> 863 <211> 882 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(859) <223> RXS00419 <400> 863 gctggttgaa gactcgaaat gagatcgacc caaccggagt ctttgcatct gacatgtccc 60 gccgacttga gctttcttaa gaaagggctt gaactaaaca atg ctt aac gca gtg 115 Met Leu Asn Ala Val 1 5 ggc aaa gcc caa aac att ctc ctt ctt ggt gga acc tct gag atc ggt 163 Gly Lys Ala Gln Asn Ile Leu Leu Leu Gly Gly Thr Ser Glu Ile Gly 10 15 20 att tcc att gtc tcc cgc ttc ctc aag cag ggt cca tcc cat gtg acc 211 Ile Ser Ile Val Ser Arg Phe Leu Lys Gln Gly Pro Ser His Val Thr 25 30 35 ttg gca gcg cgt aaa gat tcc cca cgc gtg gac gca gca gtc gca gag 259 Leu Ala Ala Arg Lys Asp Ser Pro Arg Val Asp Ala Ala Val Ala Glu 40 45 50 atc aaa gca gct ggc gct gct tcc gtt gct gtt gtt gat ttc gat gcg 307 Ile Lys Ala Ala Gly Ala Ala Ser Val Ala Val Val Asp Phe Asp Ala 55 60 65 ctc gac acc gaa tcc cac cct gca gcc atc gac gca gcc ttt gaa aac 355 Leu Asp Thr Glu Ser His Pro Ala Ala Ile Asp Ala Ala Phe Glu Asn 70 75 80 85 ggc gac gtt gac gta gca atc gtg gct ttc ggc atc ctc ggc gac aac 403 Gly Asp Val Asp Val Ala Ile Val Ala Phe Gly Ile Leu Gly Asp Asn 90 95 100 gaa gca cag tgg cgc gac caa gca cta gca gtg gaa gca acc acc gtg 451 Glu Ala Gln Trp Arg Asp Gln Ala Leu Ala Val Glu Ala Thr Thr Val 105 110 115 aac tac acc gcc ggc gtt tcc gta ggt gta ctg ctg ggc cag aaa ttt 499 Asn Tyr Thr Ala Gly Val Ser Val Gly Val Leu Leu Gly Gln Lys Phe 120 125 130 gag cag cag ggc cac ggc acc atc gtg gca ttg tcc tct gtg gca ggc 547 Glu Gln Gln Gly His Gly Thr Ile Val Ala Leu Ser Ser Val Ala Gly 135 140 145 cag cga gtc cgc cgc tcc aac ttt gtc tac ggc tcc gcc aag gca ggt 595 Gln Arg Val Arg Arg Ser Asn Phe Val Tyr Gly Ser Ala Lys Ala Gly 150 155 160 165 ttc gac ggt ttc tac acc cag ctc ggc gaa gcc ctg cgt gga tcc ggt 643 Phe Asp Gly Phe Tyr Thr Gln Leu Gly Glu Ala Leu Arg Gly Ser Gly 170 175 180 gcc aac gta ttg gtg gtt cgc cca ggc cag gta cgc acc aag atg tcc 691 Ala Asn Val Leu Val Val Arg Pro Gly Gln Val Arg Thr Lys Met Ser 185 190 195 gca gat ggt ggc gaa gcc cca ctg acc gtc aac cgc gaa gac gtg gca 739 Ala Asp Gly Gly Glu Ala Pro Leu Thr Val Asn Arg Glu Asp Val Ala 200 205 210 gat gct gtt tat gat gca gtg gtg aac aag aag gac atc atc ttt gtc 787 Asp Ala Val Tyr Asp Ala Val Val Asn Lys Lys Asp Ile Ile Phe Val 215 220 225 cac cca ctg ttc cag tac gtc tct ttt gcg ttc caa ttc att ccg cga 835 His Pro Leu Phe Gln Tyr Val Ser Phe Ala Phe Gln Phe Ile Pro Arg 230 235 240 245 gca atc ttc cgc aag ctg ccg ttc taacggaagt tacggaagtt acg 882 Ala Ile Phe Arg Lys Leu Pro Phe 250 <210> 864 <211> 253 <212> PRT <213> Corynebacterium glutamicum <400> 864 Met Leu Asn Ala Val Gly Lys Ala Gln Asn Ile Leu Leu Leu Gly Gly 1 5 10 15 Thr Ser Glu Ile Gly Ile Ser Ile Val Ser Arg Phe Leu Lys Gln Gly 20 25 30 Pro Ser His Val Thr Leu Ala Ala Arg Lys Asp Ser Pro Arg Val Asp 35 40 45 Ala Ala Val Ala Glu Ile Lys Ala Ala Gly Ala Ala Ser Val Ala Val 50 55 60 Val Asp Phe Asp Ala Leu Asp Thr Glu Ser His Pro Ala Ala Ile Asp 65 70 75 80 Ala Ala Phe Glu Asn Gly Asp Val Asp Val Ala Ile Val Ala Phe Gly 85 90 95 Ile Leu Gly Asp Asn Glu Ala Gln Trp Arg Asp Gln Ala Leu Ala Val 100 105 110 Glu Ala Thr Thr Val Asn Tyr Thr Ala Gly Val Ser Val Gly Val Leu 115 120 125 Leu Gly Gln Lys Phe Glu Gln Gln Gly His Gly Thr Ile Val Ala Leu 130 135 140 Ser Ser Val Ala Gly Gln Arg Val Arg Arg Ser Asn Phe Val Tyr Gly 145 150 155 160 Ser Ala Lys Ala Gly Phe Asp Gly Phe Tyr Thr Gln Leu Gly Glu Ala 165 170 175 Leu Arg Gly Ser Gly Ala Asn Val Leu Val Val Arg Pro Gly Gln Val 180 185 190 Arg Thr Lys Met Ser Ala Asp Gly Gly Glu Ala Pro Leu Thr Val Asn 195 200 205 Arg Glu Asp Val Ala Asp Ala Val Tyr Asp Ala Val Val Asn Lys Lys 210 215 220 Asp Ile Ile Phe Val His Pro Leu Phe Gln Tyr Val Ser Phe Ala Phe 225 230 235 240 Gln Phe Ile Pro Arg Ala Ile Phe Arg Lys Leu Pro Phe 245 250 <210> 865 <211> 1673 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1650) <223> RXC00416 <400> 865 ctg gcg tct tac tta agc cca act gcg ctg gtg gtt gcg gtg ttg gct 48 Leu Ala Ser Tyr Leu Ser Pro Thr Ala Leu Val Val Ala Val Leu Ala 1 5 10 15 att ccg ctg tct gcg acc cgc ctg tat ttg gac gga atc agc gtt gac 96 Ile Pro Leu Ser Ala Thr Arg Leu Tyr Leu Asp Gly Ile Ser Val Asp 20 25 30 cag ggc ttt aga act cag ttt tta acc cgc atg gct gac gat atc ggc 144 Gln Gly Phe Arg Thr Gln Phe Leu Thr Arg Met Ala Asp Asp Ile Gly 35 40 45 ttg tcg gac atg aac tac atc gat atg cct acc ttc tac cct gct gga 192 Leu Ser Asp Met Asn Tyr Ile Asp Met Pro Thr Phe Tyr Pro Ala Gly 50 55 60 tgg ttc tgg ctc ggt ggt cgc ttg gcc aat ctt ttg ggg ctg ccc ggt 240 Trp Phe Trp Leu Gly Gly Arg Leu Ala Asn Leu Leu Gly Leu Pro Gly 65 70 75 80 tgg gaa gct ttc cag cca tgg gca att gtg tcc atg gca gtt gct gct 288 Trp Glu Ala Phe Gln Pro Trp Ala Ile Val Ser Met Ala Val Ala Ala 85 90 95 tct gtg tta gtt cca gtg tgg cag cgc atc acc ggt tcc ctg ccg gtg 336 Ser Val Leu Val Pro Val Trp Gln Arg Ile Thr Gly Ser Leu Pro Val 100 105 110 gca aca ggc att gcg ttg gtg aca acc tgc att atc ttg gcg atg aat 384 Ala Thr Gly Ile Ala Leu Val Thr Thr Cys Ile Ile Leu Ala Met Asn 115 120 125 tcc gaa gag ccc tac gct gca atc gtt gcg atg ggt att cca gcg atg 432 Ser Glu Glu Pro Tyr Ala Ala Ile Val Ala Met Gly Ile Pro Ala Met 130 135 140 ctc gtg ctg gct tcc cgc att gcc aag ggc gat aag ttt gcg ctt gcc 480 Leu Val Leu Ala Ser Arg Ile Ala Lys Gly Asp Lys Phe Ala Leu Ala 145 150 155 160 ggc ggc att att tac ttg ggt gtt tcg gct act ttc tat act ttg ttc 528 Gly Gly Ile Ile Tyr Leu Gly Val Ser Ala Thr Phe Tyr Thr Leu Phe 165 170 175 acc ggt gct atc gcg ctt tct gcg gtc gcg gtg tgc atc gtg gtg gcg 576 Thr Gly Ala Ile Ala Leu Ser Ala Val Ala Val Cys Ile Val Val Ala 180 185 190 gct att gtg cag cgc tcc atc aaa cca ctg ctg tgg ctt gca gtg ctg 624 Ala Ile Val Gln Arg Ser Ile Lys Pro Leu Leu Trp Leu Ala Val Leu 195 200 205 ggt ggt gga tcc att gtc att gcg ttg att tct tgg ggt cct tac ctt 672 Gly Gly Gly Ser Ile Val Ile Ala Leu Ile Ser Trp Gly Pro Tyr Leu 210 215 220 ctg gcc tcc atc aac gga gcg gag cgc tct ggc gat tcc gca aca cac 720 Leu Ala Ser Ile Asn Gly Ala Glu Arg Ser Gly Asp Ser Ala Thr His 225 230 235 240 tac ctg cct ctt gaa ggc acc caa ttc ccg gtt cct ttc ttg gca tca 768 Tyr Leu Pro Leu Glu Gly Thr Gln Phe Pro Val Pro Phe Leu Ala Ser 245 250 255 agc gtt gtg gga ctg ttg tgt ctt gtt ggc ctg atc tat ttg gtg gtg 816 Ser Val Val Gly Leu Leu Cys Leu Val Gly Leu Ile Tyr Leu Val Val 260 265 270 cgt ttc cac aac aat gag gtg cgc gcg atg tgg gtc ggc atc gca gtg 864 Arg Phe His Asn Asn Glu Val Arg Ala Met Trp Val Gly Ile Ala Val 275 280 285 ttt tat gcc tgg atg ggc atg tcc atg gcg atc acg ctt ttg ggc aac 912 Phe Tyr Ala Trp Met Gly Met Ser Met Ala Ile Thr Leu Leu Gly Asn 290 295 300 acg ttg ctt gga ttc cgt ctt gat acg gtg ctg gtg ctt att ttt gcc 960 Thr Leu Leu Gly Phe Arg Leu Asp Thr Val Leu Val Leu Ile Phe Ala 305 310 315 320 acg gct gga gtg ttg ggc att gca gat ttc cgc ctt gcc agt gtg tat 1008 Thr Ala Gly Val Leu Gly Ile Ala Asp Phe Arg Leu Ala Ser Val Tyr 325 330 335 cag ctc tac ccc acc caa atc aca gag cgc acg gcc acc cat ctg acc 1056 Gln Leu Tyr Pro Thr Gln Ile Thr Glu Arg Thr Ala Thr His Leu Thr 340 345 350 aat cta att gtg gtc ctc gtg ctg ctt ggc ggc ctc tac tac gcg caa 1104 Asn Leu Ile Val Val Leu Val Leu Leu Gly Gly Leu Tyr Tyr Ala Gln 355 360 365 gat ctg ccg cag aag aac gca cga gct atc gat ctg gcc tat acc gat 1152 Asp Leu Pro Gln Lys Asn Ala Arg Ala Ile Asp Leu Ala Tyr Thr Asp 370 375 380 act gat ggc tac ggc gag cgc gcg gat ctg tat ccg gcc gga gct gca 1200 Thr Asp Gly Tyr Gly Glu Arg Ala Asp Leu Tyr Pro Ala Gly Ala Ala 385 390 395 400 cgt tat tac aag gac atc aac gat cat ctg ctt gat caa gga ttc gag 1248 Arg Tyr Tyr Lys Asp Ile Asn Asp His Leu Leu Asp Gln Gly Phe Glu 405 410 415 cct tcc gaa act gtc gtg ctg aca gac gaa ctc gat ttc atg tcc tac 1296 Pro Ser Glu Thr Val Val Leu Thr Asp Glu Leu Asp Phe Met Ser Tyr 420 425 430 tac cct tat cgc gga tac caa gct ttt act tcc cac tac gcc aac ccg 1344 Tyr Pro Tyr Arg Gly Tyr Gln Ala Phe Thr Ser His Tyr Ala Asn Pro 435 440 445 ctt ggt gag ttc gga aac agg aac gca ttc atc gaa gat ctc gcg atc 1392 Leu Gly Glu Phe Gly Asn Arg Asn Ala Phe Ile Glu Asp Leu Ala Ile 450 455 460 cga agc tgg gat gag ttg gct gat cct caa caa ttc agc gac gcc ttg 1440 Arg Ser Trp Asp Glu Leu Ala Asp Pro Gln Gln Phe Ser Asp Ala Leu 465 470 475 480 aac acc tct cca tgg acg atc cct gag gtg ttc atc ttc cgt ggc tcc 1488 Asn Thr Ser Pro Trp Thr Ile Pro Glu Val Phe Ile Phe Arg Gly Ser 485 490 495 atc gat gat cct gac gcc ggt tgg aaa tac gac gtg gct gaa gat ctg 1536 Ile Asp Asp Pro Asp Ala Gly Trp Lys Tyr Asp Val Ala Glu Asp Leu 500 505 510 tac ccg aac aat cca aac gtg cgc ttc cgc ggc gtg tac ttt aac ccg 1584 Tyr Pro Asn Asn Pro Asn Val Arg Phe Arg Gly Val Tyr Phe Asn Pro 515 520 525 gag tca ttt gat cag atg tgg cag acc aag caa gtg gga cct ttc gtg 1632 Glu Ser Phe Asp Gln Met Trp Gln Thr Lys Gln Val Gly Pro Phe Val 530 535 540 gtg gta acg cac aat gag taattcctca ccaaacgacc caa 1673 Val Val Thr His Asn Glu 545 550 <210> 866 <211> 550 <212> PRT <213> Corynebacterium glutamicum <400> 866 Leu Ala Ser Tyr Leu Ser Pro Thr Ala Leu Val Val Ala Val Leu Ala 1 5 10 15 Ile Pro Leu Ser Ala Thr Arg Leu Tyr Leu Asp Gly Ile Ser Val Asp 20 25 30 Gln Gly Phe Arg Thr Gln Phe Leu Thr Arg Met Ala Asp Asp Ile Gly 35 40 45 Leu Ser Asp Met Asn Tyr Ile Asp Met Pro Thr Phe Tyr Pro Ala Gly 50 55 60 Trp Phe Trp Leu Gly Gly Arg Leu Ala Asn Leu Leu Gly Leu Pro Gly 65 70 75 80 Trp Glu Ala Phe Gln Pro Trp Ala Ile Val Ser Met Ala Val Ala Ala 85 90 95 Ser Val Leu Val Pro Val Trp Gln Arg Ile Thr Gly Ser Leu Pro Val 100 105 110 Ala Thr Gly Ile Ala Leu Val Thr Thr Cys Ile Ile Leu Ala Met Asn 115 120 125 Ser Glu Glu Pro Tyr Ala Ala Ile Val Ala Met Gly Ile Pro Ala Met 130 135 140 Leu Val Leu Ala Ser Arg Ile Ala Lys Gly Asp Lys Phe Ala Leu Ala 145 150 155 160 Gly Gly Ile Ile Tyr Leu Gly Val Ser Ala Thr Phe Tyr Thr Leu Phe 165 170 175 Thr Gly Ala Ile Ala Leu Ser Ala Val Ala Val Cys Ile Val Val Ala 180 185 190 Ala Ile Val Gln Arg Ser Ile Lys Pro Leu Leu Trp Leu Ala Val Leu 195 200 205 Gly Gly Gly Ser Ile Val Ile Ala Leu Ile Ser Trp Gly Pro Tyr Leu 210 215 220 Leu Ala Ser Ile Asn Gly Ala Glu Arg Ser Gly Asp Ser Ala Thr His 225 230 235 240 Tyr Leu Pro Leu Glu Gly Thr Gln Phe Pro Val Pro Phe Leu Ala Ser 245 250 255 Ser Val Val Gly Leu Leu Cys Leu Val Gly Leu Ile Tyr Leu Val Val 260 265 270 Arg Phe His Asn Asn Glu Val Arg Ala Met Trp Val Gly Ile Ala Val 275 280 285 Phe Tyr Ala Trp Met Gly Met Ser Met Ala Ile Thr Leu Leu Gly Asn 290 295 300 Thr Leu Leu Gly Phe Arg Leu Asp Thr Val Leu Val Leu Ile Phe Ala 305 310 315 320 Thr Ala Gly Val Leu Gly Ile Ala Asp Phe Arg Leu Ala Ser Val Tyr 325 330 335 Gln Leu Tyr Pro Thr Gln Ile Thr Glu Arg Thr Ala Thr His Leu Thr 340 345 350 Asn Leu Ile Val Val Leu Val Leu Leu Gly Gly Leu Tyr Tyr Ala Gln 355 360 365 Asp Leu Pro Gln Lys Asn Ala Arg Ala Ile Asp Leu Ala Tyr Thr Asp 370 375 380 Thr Asp Gly Tyr Gly Glu Arg Ala Asp Leu Tyr Pro Ala Gly Ala Ala 385 390 395 400 Arg Tyr Tyr Lys Asp Ile Asn Asp His Leu Leu Asp Gln Gly Phe Glu 405 410 415 Pro Ser Glu Thr Val Val Leu Thr Asp Glu Leu Asp Phe Met Ser Tyr 420 425 430 Tyr Pro Tyr Arg Gly Tyr Gln Ala Phe Thr Ser His Tyr Ala Asn Pro 435 440 445 Leu Gly Glu Phe Gly Asn Arg Asn Ala Phe Ile Glu Asp Leu Ala Ile 450 455 460 Arg Ser Trp Asp Glu Leu Ala Asp Pro Gln Gln Phe Ser Asp Ala Leu 465 470 475 480 Asn Thr Ser Pro Trp Thr Ile Pro Glu Val Phe Ile Phe Arg Gly Ser 485 490 495 Ile Asp Asp Pro Asp Ala Gly Trp Lys Tyr Asp Val Ala Glu Asp Leu 500 505 510 Tyr Pro Asn Asn Pro Asn Val Arg Phe Arg Gly Val Tyr Phe Asn Pro 515 520 525 Glu Ser Phe Asp Gln Met Trp Gln Thr Lys Gln Val Gly Pro Phe Val 530 535 540 Val Val Thr His Asn Glu 545 550 <210> 867 <211> 1059 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1036) <223> RXC02206 <400> 867 ggcaggatct gctgctgcgg ctaggagggt tatctcttca ttcacccgat ctaccgtact 60 accttatgac ctcagtagtg tggtgggcgt gaaacagcga atg gtc ggt tca agt 115 Met Val Gly Ser Ser 1 5 ggt ttg cgg gta tcc agg ctc ggt ttg ggc acc tca aca tgg ggc tcg 163 Gly Leu Arg Val Ser Arg Leu Gly Leu Gly Thr Ser Thr Trp Gly Ser 10 15 20 ggc acc gag ctg gct gag gca ggc gat atc ttt aag gcg ttc atc aat 211 Gly Thr Glu Leu Ala Glu Ala Gly Asp Ile Phe Lys Ala Phe Ile Asn 25 30 35 tct ggt ggc acg ctt atc gac gtc tcc ccc aac tac acc acc ggc gtc 259 Ser Gly Gly Thr Leu Ile Asp Val Ser Pro Asn Tyr Thr Thr Gly Val 40 45 50 gcg gaa gaa atg ctc ggc acg atg ttg gat gcg gaa gtc tct cgt tcg 307 Ala Glu Glu Met Leu Gly Thr Met Leu Asp Ala Glu Val Ser Arg Ser 55 60 65 gct gtc gtc att tcc tcc agc gca ggt gtc aac ccc gct ctg ccg ctc 355 Ala Val Val Ile Ser Ser Ser Ala Gly Val Asn Pro Ala Leu Pro Leu 70 75 80 85 ggc cga cgt gtg gat tgc tcc cgc cgc aat ttg att gcc caa tta gat 403 Gly Arg Arg Val Asp Cys Ser Arg Arg Asn Leu Ile Ala Gln Leu Asp 90 95 100 gtc acc ctg cgg gca tta aac act gac tat ttg gat ttg tgg tct gtg 451 Val Thr Leu Arg Ala Leu Asn Thr Asp Tyr Leu Asp Leu Trp Ser Val 105 110 115 ggc tat tgg gat gag ggc acc cca ccg cat gag gtg gcc gat act ttg 499 Gly Tyr Trp Asp Glu Gly Thr Pro Pro His Glu Val Ala Asp Thr Leu 120 125 130 gat tac gcc gtg cgc acc ggc cga gtc cga tat gcc ggt gtc cga gga 547 Asp Tyr Ala Val Arg Thr Gly Arg Val Arg Tyr Ala Gly Val Arg Gly 135 140 145 tat tcc ggt tgg cag tta gcg gtc acc cac gct gca tcc aat cat gca 595 Tyr Ser Gly Trp Gln Leu Ala Val Thr His Ala Ala Ser Asn His Ala 150 155 160 165 gcg gcc tcc gcc cgc ccc gtg gtc gtt gca caa aat gaa tac agc ctg 643 Ala Ala Ser Ala Arg Pro Val Val Val Ala Gln Asn Glu Tyr Ser Leu 170 175 180 ctg gaa cgc cgc gca gaa caa gaa ctc ctc cct gcc acc caa cac cta 691 Leu Glu Arg Arg Ala Glu Gln Glu Leu Leu Pro Ala Thr Gln His Leu 185 190 195 ggt gtc gga ttc ttt gct ggc gct ccg ctg ggg caa ggc gtg ctg act 739 Gly Val Gly Phe Phe Ala Gly Ala Pro Leu Gly Gln Gly Val Leu Thr 200 205 210 gct aaa tac cgc tcc gaa att ccc cat gat tcc aga gct gca tcc aca 787 Ala Lys Tyr Arg Ser Glu Ile Pro His Asp Ser Arg Ala Ala Ser Thr 215 220 225 gga cgc gac gca gaa gtc caa agc tac cta gat aat cga ggc cgc atc 835 Gly Arg Asp Ala Glu Val Gln Ser Tyr Leu Asp Asn Arg Gly Arg Ile 230 235 240 245 att gtc gat gct ctt gat act gca gcc aaa gga tta ggc att agc ccc 883 Ile Val Asp Ala Leu Asp Thr Ala Ala Lys Gly Leu Gly Ile Ser Pro 250 255 260 gct gtc aca gcc acc acc tgg gtg cgt gat cgt ccc gga gtg aca gct 931 Ala Val Thr Ala Thr Thr Trp Val Arg Asp Arg Pro Gly Val Thr Ala 265 270 275 gtc atc gtg ggc gct cgc aca cat gaa cag ctg tca cat ctt ctc aag 979 Val Ile Val Gly Ala Arg Thr His Glu Gln Leu Ser His Leu Leu Lys 280 285 290 gcg gaa tcg gtg act ttg cca aca cca atc aca caa gcc ctt gat gat 1027 Ala Glu Ser Val Thr Leu Pro Thr Pro Ile Thr Gln Ala Leu Asp Asp 295 300 305 gtc tcc ctg tgacttggtc caattacatt cac 1059 Val Ser Leu 310 <210> 868 <211> 312 <212> PRT <213> Corynebacterium glutamicum <400> 868 Met Val Gly Ser Ser Gly Leu Arg Val Ser Arg Leu Gly Leu Gly Thr 1 5 10 15 Ser Thr Trp Gly Ser Gly Thr Glu Leu Ala Glu Ala Gly Asp Ile Phe 20 25 30 Lys Ala Phe Ile Asn Ser Gly Gly Thr Leu Ile Asp Val Ser Pro Asn 35 40 45 Tyr Thr Thr Gly Val Ala Glu Glu Met Leu Gly Thr Met Leu Asp Ala 50 55 60 Glu Val Ser Arg Ser Ala Val Val Ile Ser Ser Ser Ala Gly Val Asn 65 70 75 80 Pro Ala Leu Pro Leu Gly Arg Arg Val Asp Cys Ser Arg Arg Asn Leu 85 90 95 Ile Ala Gln Leu Asp Val Thr Leu Arg Ala Leu Asn Thr Asp Tyr Leu 100 105 110 Asp Leu Trp Ser Val Gly Tyr Trp Asp Glu Gly Thr Pro Pro His Glu 115 120 125 Val Ala Asp Thr Leu Asp Tyr Ala Val Arg Thr Gly Arg Val Arg Tyr 130 135 140 Ala Gly Val Arg Gly Tyr Ser Gly Trp Gln Leu Ala Val Thr His Ala 145 150 155 160 Ala Ser Asn His Ala Ala Ala Ser Ala Arg Pro Val Val Val Ala Gln 165 170 175 Asn Glu Tyr Ser Leu Leu Glu Arg Arg Ala Glu Gln Glu Leu Leu Pro 180 185 190 Ala Thr Gln His Leu Gly Val Gly Phe Phe Ala Gly Ala Pro Leu Gly 195 200 205 Gln Gly Val Leu Thr Ala Lys Tyr Arg Ser Glu Ile Pro His Asp Ser 210 215 220 Arg Ala Ala Ser Thr Gly Arg Asp Ala Glu Val Gln Ser Tyr Leu Asp 225 230 235 240 Asn Arg Gly Arg Ile Ile Val Asp Ala Leu Asp Thr Ala Ala Lys Gly 245 250 255 Leu Gly Ile Ser Pro Ala Val Thr Ala Thr Thr Trp Val Arg Asp Arg 260 265 270 Pro Gly Val Thr Ala Val Ile Val Gly Ala Arg Thr His Glu Gln Leu 275 280 285 Ser His Leu Leu Lys Ala Glu Ser Val Thr Leu Pro Thr Pro Ile Thr 290 295 300 Gln Ala Leu Asp Asp Val Ser Leu 305 310 <210> 869 <211> 621 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(598) <223> RXS03074 <400> 869 tttgtgggca atctggtttt ttcgtaattg tgtgggatga atctcttaaa aattcacatt 60 tagcaggaca agcatactgt tttagttcta tgctgtgggc atg act caa agt gct 115 Met Thr Gln Ser Ala 1 5 cca gaa ttc att gcc acc gca gac ctc gta gac atc atc ggc gac aac 163 Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp Ile Ile Gly Asp Asn 10 15 20 gcg caa tca tgc gac act cag ttt caa aac ctt gga ggt gcc aca gaa 211 Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu Gly Gly Ala Thr Glu 25 30 35 ttc cac gga ata ata acc acc gtg aaa tgc ttc caa gac aac gcc ctc 259 Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe Gln Asp Asn Ala Leu 40 45 50 ctg aaa tcc atc ctg agc gag gat aat cct ggg gga gtg ctg gtt atc 307 Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly Gly Val Leu Val Ile 55 60 65 gat ggc gac gca tcc gtg cac acc gcg cta gtt ggc gac atc att gca 355 Asp Gly Asp Ala Ser Val His Thr Ala Leu Val Gly Asp Ile Ile Ala 70 75 80 85 gga ctt gga aaa gat cat ggt tgg tcc gga gta att gtc aac gga gca 403 Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val Ile Val Asn Gly Ala 90 95 100 att cga gac tcc gca gtc atc ggc acc atg acc ttt ggt tgt aaa gcc 451 Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr Phe Gly Cys Lys Ala 105 110 115 ctt gga acc aac ccg cgg aaa tcc act aaa act ggt tcc ggc gaa cga 499 Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr Gly Ser Gly Glu Arg 120 125 130 gac gta gtg gta tcg att ggt ggc att gac ttc att cct ggt cat tac 547 Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe Ile Pro Gly His Tyr 135 140 145 gtc tac gcg gac tct gac gga att atc gtc acc gag gcg cca att aag 595 Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr Glu Ala Pro Ile Lys 150 155 160 165 cag taatttgttt tgacgacgca gta 621 Gln <210> 870 <211> 166 <212> PRT <213> Corynebacterium glutamicum <400> 870 Met Thr Gln Ser Ala Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp 1 5 10 15 Ile Ile Gly Asp Asn Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu 20 25 30 Gly Gly Ala Thr Glu Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe 35 40 45 Gln Asp Asn Ala Leu Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly 50 55 60 Gly Val Leu Val Ile Asp Gly Asp Ala Ser Val His Thr Ala Leu Val 65 70 75 80 Gly Asp Ile Ile Ala Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val 85 90 95 Ile Val Asn Gly Ala Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr 100 105 110 Phe Gly Cys Lys Ala Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr 115 120 125 Gly Ser Gly Glu Arg Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe 130 135 140 Ile Pro Gly His Tyr Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr 145 150 155 160 Glu Ala Pro Ile Lys Gln 165 <210> 871 <211> 621 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(598) <223> FRXA02906 <400> 871 tttgtgggca atctggtttt ttcgtaattg tgtgggatga atctcttaaa aattcacatt 60 tagcaggaca agcatactgt tttagttcta tgctgtgggc atg act caa agt gct 115 Met Thr Gln Ser Ala 1 5 cca gaa ttc att gcc acc gca gac ctc gta gac atc atc ggc gac aac 163 Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp Ile Ile Gly Asp Asn 10 15 20 gcg caa tca tgc gac act cag ttt caa aac ctt gga ggt gcc aca gaa 211 Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu Gly Gly Ala Thr Glu 25 30 35 ttc cac gga ata ata acc acc gtg aaa tgc ttc caa gac aac gcc ctc 259 Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe Gln Asp Asn Ala Leu 40 45 50 ctg aaa tcc atc ctg agc gag gat aat cct ggg gga gtg ctg gtt atc 307 Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly Gly Val Leu Val Ile 55 60 65 gat ggc gac gca tcc gtg cac acc gcg cta gtt ggc gac atc att gca 355 Asp Gly Asp Ala Ser Val His Thr Ala Leu Val Gly Asp Ile Ile Ala 70 75 80 85 gga ctt gga aaa gat cat ggt tgg tcc gga gta att gtc aac gga gca 403 Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val Ile Val Asn Gly Ala 90 95 100 att cga gac tcc gca gtc atc ggc acc atg acc ttt ggt tgt aaa gcc 451 Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr Phe Gly Cys Lys Ala 105 110 115 ctt gga acc aac ccg cgg aaa tcc act aaa act ggt tcc ggc gaa cga 499 Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr Gly Ser Gly Glu Arg 120 125 130 gac gta gtg gta tcg att ggt ggc att gac ttc att cct ggt cat tac 547 Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe Ile Pro Gly His Tyr 135 140 145 gtc tac gcg gac tct gac gga att atc gtc acc gag gcg cca att aag 595 Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr Glu Ala Pro Ile Lys 150 155 160 165 cag taatttgttt tgacgacgca gta 621 Gln <210> 872 <211> 166 <212> PRT <213> Corynebacterium glutamicum <400> 872 Met Thr Gln Ser Ala Pro Glu Phe Ile Ala Thr Ala Asp Leu Val Asp 1 5 10 15 Ile Ile Gly Asp Asn Ala Gln Ser Cys Asp Thr Gln Phe Gln Asn Leu 20 25 30 Gly Gly Ala Thr Glu Phe His Gly Ile Ile Thr Thr Val Lys Cys Phe 35 40 45 Gln Asp Asn Ala Leu Leu Lys Ser Ile Leu Ser Glu Asp Asn Pro Gly 50 55 60 Gly Val Leu Val Ile Asp Gly Asp Ala Ser Val His Thr Ala Leu Val 65 70 75 80 Gly Asp Ile Ile Ala Gly Leu Gly Lys Asp His Gly Trp Ser Gly Val 85 90 95 Ile Val Asn Gly Ala Ile Arg Asp Ser Ala Val Ile Gly Thr Met Thr 100 105 110 Phe Gly Cys Lys Ala Leu Gly Thr Asn Pro Arg Lys Ser Thr Lys Thr 115 120 125 Gly Ser Gly Glu Arg Asp Val Val Val Ser Ile Gly Gly Ile Asp Phe 130 135 140 Ile Pro Gly His Tyr Val Tyr Ala Asp Ser Asp Gly Ile Ile Val Thr 145 150 155 160 Glu Ala Pro Ile Lys Gln 165 <210> 873 <211> 1752 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1729) <223> RXA02315 <400> 873 cgtttggaaa cgcttgctgc cagcaaagat aggcgtgatt ggtggtttga gcgcgtgcgt 60 gaatcgtatc cgtacctgga gacgatctag actgttgtgc atg tcc agc acg cca 115 Met Ser Ser Thr Pro 1 5 gct caa gat ctt gcc cgc gcc gtt att gat tcc ctc gca cca cac gtc 163 Ala Gln Asp Leu Ala Arg Ala Val Ile Asp Ser Leu Ala Pro His Val 10 15 20 act gac gtg gtg tta tgc cca gga tcc agg aac tca ccg ttg tcg ctt 211 Thr Asp Val Val Leu Cys Pro Gly Ser Arg Asn Ser Pro Leu Ser Leu 25 30 35 gag ttg ctg gcg cgg cag gat ctg cgt gtc cat gtg cgt atc gac gag 259 Glu Leu Leu Ala Arg Gln Asp Leu Arg Val His Val Arg Ile Asp Glu 40 45 50 cgc agc gcc tca ttt ttg gcg ctg tcc cta gcg cgt acc cag gcc cgg 307 Arg Ser Ala Ser Phe Leu Ala Leu Ser Leu Ala Arg Thr Gln Ala Arg 55 60 65 ccg gtg gct gtg gtg atg acc tcc ggc acg gct gta gct aac tgc ctg 355 Pro Val Ala Val Val Met Thr Ser Gly Thr Ala Val Ala Asn Cys Leu 70 75 80 85 cct gct gtt gct gaa gct gcg cat gcc cat atc ccg ttg att gtg ctc 403 Pro Ala Val Ala Glu Ala Ala His Ala His Ile Pro Leu Ile Val Leu 90 95 100 tct gct gac cgt cct gca cat ttg gtg gga acg ggg gcg agc caa acg 451 Ser Ala Asp Arg Pro Ala His Leu Val Gly Thr Gly Ala Ser Gln Thr 105 110 115 att aac cag acc ggt att ttt ggt gat ctt gca ccg acg gtc ggt atc 499 Ile Asn Gln Thr Gly Ile Phe Gly Asp Leu Ala Pro Thr Val Gly Ile 120 125 130 act gag ctg gat cag gta gcg cag att gct gaa agc ctt gct cag ggg 547 Thr Glu Leu Asp Gln Val Ala Gln Ile Ala Glu Ser Leu Ala Gln Gly 135 140 145 gct tcc cag att ccg cgt cat ttc aat ctt gca ctt gat gtt cct ttg 595 Ala Ser Gln Ile Pro Arg His Phe Asn Leu Ala Leu Asp Val Pro Leu 150 155 160 165 gtt gct cct gaa ctg cca gag ctt cat ggt gag gca gtt gga gca tca 643 Val Ala Pro Glu Leu Pro Glu Leu His Gly Glu Ala Val Gly Ala Ser 170 175 180 tgg acg cat cgc tgg atc aac cac ggt gag gtg acc gtg gac ctg ggg 691 Trp Thr His Arg Trp Ile Asn His Gly Glu Val Thr Val Asp Leu Gly 185 190 195 gag cac acc ctc gtg att gcc ggt gat gaa gca tgg gaa gtg gaa ggg 739 Glu His Thr Leu Val Ile Ala Gly Asp Glu Ala Trp Glu Val Glu Gly 200 205 210 ctg gaa gat gtg ccc acc atc gct gaa cct act gca cca aag cct tat 787 Leu Glu Asp Val Pro Thr Ile Ala Glu Pro Thr Ala Pro Lys Pro Tyr 215 220 225 aat ccg gtg cac cca ctg gct gct gaa atc ttg ctg aag gag cag gtc 835 Asn Pro Val His Pro Leu Ala Ala Glu Ile Leu Leu Lys Glu Gln Val 230 235 240 245 tcc gcg gaa ggc tat gtg gta aac acc agg cct gat cat gtg atc gtg 883 Ser Ala Glu Gly Tyr Val Val Asn Thr Arg Pro Asp His Val Ile Val 250 255 260 gtg gga cac ccc acg ctg cac cgc gga gtg ttg aag ttg atg tca gat 931 Val Gly His Pro Thr Leu His Arg Gly Val Leu Lys Leu Met Ser Asp 265 270 275 cct ggc att aaa tta act gtg ctt tca cgc acc gat atc atc act gat 979 Pro Gly Ile Lys Leu Thr Val Leu Ser Arg Thr Asp Ile Ile Thr Asp 280 285 290 ccc ggc cgc cat gcc gat cag gtg ggc agc aca gtg aaa gtc acc ggc 1027 Pro Gly Arg His Ala Asp Gln Val Gly Ser Thr Val Lys Val Thr Gly 295 300 305 acc cag gaa aag cag tgg cta aag atc tgt tcg gca gca tca gaa ctt 1075 Thr Gln Glu Lys Gln Trp Leu Lys Ile Cys Ser Ala Ala Ser Glu Leu 310 315 320 325 gcg gcc gat ggt gtg cgt gac gtc ctg gac aac caa gaa ttc ggt ttc 1123 Ala Ala Asp Gly Val Arg Asp Val Leu Asp Asn Gln Glu Phe Gly Phe 330 335 340 acc ggc ctc cat gtt gcc gca gcc gtg gcg gat acc tta ggc acc ggc 1171 Thr Gly Leu His Val Ala Ala Ala Val Ala Asp Thr Leu Gly Thr Gly 345 350 355 gat act ctc ttt gct gca gca tcc aac tca atc cgt gac ctc tcc ctg 1219 Asp Thr Leu Phe Ala Ala Ala Ser Asn Ser Ile Arg Asp Leu Ser Leu 360 365 370 gtg ggt atg cct ttt gat ggc gtg gat acc ttc tcc cca cga ggt gtc 1267 Val Gly Met Pro Phe Asp Gly Val Asp Thr Phe Ser Pro Arg Gly Val 375 380 385 gca ggc att gat ggt tct gtt gct caa gca atc ggc act tca ctt gct 1315 Ala Gly Ile Asp Gly Ser Val Ala Gln Ala Ile Gly Thr Ser Leu Ala 390 395 400 405 gtg cag tcc cgc cac ccc gat gaa atc cgc gcg cca cgc act gtg gcc 1363 Val Gln Ser Arg His Pro Asp Glu Ile Arg Ala Pro Arg Thr Val Ala 410 415 420 ctt ctg ggc gat ctg tcg ttc ctt cac gat att ggc gga ctg ctc atc 1411 Leu Leu Gly Asp Leu Ser Phe Leu His Asp Ile Gly Gly Leu Leu Ile 425 430 435 ggc cct gat gaa cca cgc cca gaa aac ctc acc atc gtg gtc tcc aac 1459 Gly Pro Asp Glu Pro Arg Pro Glu Asn Leu Thr Ile Val Val Ser Asn 440 445 450 gac aac ggt ggc gga atc ttc gaa ctc cta gaa acc ggc gca gat ggt 1507 Asp Asn Gly Gly Gly Ile Phe Glu Leu Leu Glu Thr Gly Ala Asp Gly 455 460 465 ctc cgc ccc aac ttc gag cgt gct ttc ggt acc cca cac gac gcg tcc 1555 Leu Arg Pro Asn Phe Glu Arg Ala Phe Gly Thr Pro His Asp Ala Ser 470 475 480 485 atc gcg gat ctc tgc gca ggc tac ggc att gaa cac caa gtg gta gac 1603 Ile Ala Asp Leu Cys Ala Gly Tyr Gly Ile Glu His Gln Val Val Asp 490 495 500 aac ctc caa gac ctc atc atc gcg cta gtt gat acc acc gaa gta tcc 1651 Asn Leu Gln Asp Leu Ile Ile Ala Leu Val Asp Thr Thr Glu Val Ser 505 510 515 gga ttc acc att att gaa gct tcg acc gtc cga gat acc cgc cgt gca 1699 Gly Phe Thr Ile Ile Glu Ala Ser Thr Val Arg Asp Thr Arg Arg Ala 520 525 530 caa cag caa gct ctc atg gac acg gtg cac taaatggagt ggtaccaagt 1749 Gln Gln Gln Ala Leu Met Asp Thr Val His 535 540 gcg 1752 <210> 874 <211> 543 <212> PRT <213> Corynebacterium glutamicum <400> 874 Met Ser Ser Thr Pro Ala Gln Asp Leu Ala Arg Ala Val Ile Asp Ser 1 5 10 15 Leu Ala Pro His Val Thr Asp Val Val Leu Cys Pro Gly Ser Arg Asn 20 25 30 Ser Pro Leu Ser Leu Glu Leu Leu Ala Arg Gln Asp Leu Arg Val His 35 40 45 Val Arg Ile Asp Glu Arg Ser Ala Ser Phe Leu Ala Leu Ser Leu Ala 50 55 60 Arg Thr Gln Ala Arg Pro Val Ala Val Val Met Thr Ser Gly Thr Ala 65 70 75 80 Val Ala Asn Cys Leu Pro Ala Val Ala Glu Ala Ala His Ala His Ile 85 90 95 Pro Leu Ile Val Leu Ser Ala Asp Arg Pro Ala His Leu Val Gly Thr 100 105 110 Gly Ala Ser Gln Thr Ile Asn Gln Thr Gly Ile Phe Gly Asp Leu Ala 115 120 125 Pro Thr Val Gly Ile Thr Glu Leu Asp Gln Val Ala Gln Ile Ala Glu 130 135 140 Ser Leu Ala Gln Gly Ala Ser Gln Ile Pro Arg His Phe Asn Leu Ala 145 150 155 160 Leu Asp Val Pro Leu Val Ala Pro Glu Leu Pro Glu Leu His Gly Glu 165 170 175 Ala Val Gly Ala Ser Trp Thr His Arg Trp Ile Asn His Gly Glu Val 180 185 190 Thr Val Asp Leu Gly Glu His Thr Leu Val Ile Ala Gly Asp Glu Ala 195 200 205 Trp Glu Val Glu Gly Leu Glu Asp Val Pro Thr Ile Ala Glu Pro Thr 210 215 220 Ala Pro Lys Pro Tyr Asn Pro Val His Pro Leu Ala Ala Glu Ile Leu 225 230 235 240 Leu Lys Glu Gln Val Ser Ala Glu Gly Tyr Val Val Asn Thr Arg Pro 245 250 255 Asp His Val Ile Val Val Gly His Pro Thr Leu His Arg Gly Val Leu 260 265 270 Lys Leu Met Ser Asp Pro Gly Ile Lys Leu Thr Val Leu Ser Arg Thr 275 280 285 Asp Ile Ile Thr Asp Pro Gly Arg His Ala Asp Gln Val Gly Ser Thr 290 295 300 Val Lys Val Thr Gly Thr Gln Glu Lys Gln Trp Leu Lys Ile Cys Ser 305 310 315 320 Ala Ala Ser Glu Leu Ala Ala Asp Gly Val Arg Asp Val Leu Asp Asn 325 330 335 Gln Glu Phe Gly Phe Thr Gly Leu His Val Ala Ala Ala Val Ala Asp 340 345 350 Thr Leu Gly Thr Gly Asp Thr Leu Phe Ala Ala Ala Ser Asn Ser Ile 355 360 365 Arg Asp Leu Ser Leu Val Gly Met Pro Phe Asp Gly Val Asp Thr Phe 370 375 380 Ser Pro Arg Gly Val Ala Gly Ile Asp Gly Ser Val Ala Gln Ala Ile 385 390 395 400 Gly Thr Ser Leu Ala Val Gln Ser Arg His Pro Asp Glu Ile Arg Ala 405 410 415 Pro Arg Thr Val Ala Leu Leu Gly Asp Leu Ser Phe Leu His Asp Ile 420 425 430 Gly Gly Leu Leu Ile Gly Pro Asp Glu Pro Arg Pro Glu Asn Leu Thr 435 440 445 Ile Val Val Ser Asn Asp Asn Gly Gly Gly Ile Phe Glu Leu Leu Glu 450 455 460 Thr Gly Ala Asp Gly Leu Arg Pro Asn Phe Glu Arg Ala Phe Gly Thr 465 470 475 480 Pro His Asp Ala Ser Ile Ala Asp Leu Cys Ala Gly Tyr Gly Ile Glu 485 490 495 His Gln Val Val Asp Asn Leu Gln Asp Leu Ile Ile Ala Leu Val Asp 500 505 510 Thr Thr Glu Val Ser Gly Phe Thr Ile Ile Glu Ala Ser Thr Val Arg 515 520 525 Asp Thr Arg Arg Ala Gln Gln Gln Ala Leu Met Asp Thr Val His 530 535 540 <210> 875 <211> 1080 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1057) <223> RXA02319 <400> 875 atgtgggtga gataaccgac cgtgatgtcg ccctagcaaa agtcatcgac gcccacgcca 60 agaccttggc catttcggca gaggcttaag gttaaagatt atg agc aac tac agc 115 Met Ser Asn Tyr Ser 1 5 acc gac aac cct ttt gat ccc acc caa tgg gcc acc gtt cca ggt ttt 163 Thr Asp Asn Pro Phe Asp Pro Thr Gln Trp Ala Thr Val Pro Gly Phe 10 15 20 gaa gaa ttc acc gac atc acc tac cac cgc cac gtg ggc acc acc cgc 211 Glu Glu Phe Thr Asp Ile Thr Tyr His Arg His Val Gly Thr Thr Arg 25 30 35 gcc gat ggc atc gtg cgc atc gcc ttc gac cgc ccc gaa gtt cgc aat 259 Ala Asp Gly Ile Val Arg Ile Ala Phe Asp Arg Pro Glu Val Arg Asn 40 45 50 gct ttc cgc ccc cac acc gtc gac gag ctt tac caa gcc ctc gac cac 307 Ala Phe Arg Pro His Thr Val Asp Glu Leu Tyr Gln Ala Leu Asp His 55 60 65 gcg cgc cgg acc cca gat gtt gga acc atc ctg ctc acc ggc aac ggc 355 Ala Arg Arg Thr Pro Asp Val Gly Thr Ile Leu Leu Thr Gly Asn Gly 70 75 80 85 ccc agc gaa aaa gac ggt ggc tgg gcg ttc tgc tcc ggc ggc gac caa 403 Pro Ser Glu Lys Asp Gly Gly Trp Ala Phe Cys Ser Gly Gly Asp Gln 90 95 100 cgc atc cgc ggg cgc tcc ggc tac caa tac gcc acc gaa cac gcg cgc 451 Arg Ile Arg Gly Arg Ser Gly Tyr Gln Tyr Ala Thr Glu His Ala Arg 105 110 115 gac gat gcc acc gct gat gtc ttc acg gta gat att gcc cgc acc aaa 499 Asp Asp Ala Thr Ala Asp Val Phe Thr Val Asp Ile Ala Arg Thr Lys 120 125 130 gtt gaa ggc gga cgc ctc cac att ttg gaa gtc caa cgc ctc atc cgc 547 Val Glu Gly Gly Arg Leu His Ile Leu Glu Val Gln Arg Leu Ile Arg 135 140 145 acc atg cct aaa gtt gtc atc gca gta gtc aac ggc tgg gca gcc ggc 595 Thr Met Pro Lys Val Val Ile Ala Val Val Asn Gly Trp Ala Ala Gly 150 155 160 165 ggt ggg cac tcc ctc cat gtc gtt tgc gac ctc acc atc gct tcc cgc 643 Gly Gly His Ser Leu His Val Val Cys Asp Leu Thr Ile Ala Ser Arg 170 175 180 caa gaa gca cgc ttc aag caa acc gac gct gac gtg gga tcc ttc gac 691 Gln Glu Ala Arg Phe Lys Gln Thr Asp Ala Asp Val Gly Ser Phe Asp 185 190 195 gct ggc tac ggc tcc gcc tac cta gcg aaa atg gtc gga cag aaa aac 739 Ala Gly Tyr Gly Ser Ala Tyr Leu Ala Lys Met Val Gly Gln Lys Asn 200 205 210 gcc cgc gaa atc ttc ttc ctc gga cgc acc tac gac gcc gaa cgc atg 787 Ala Arg Glu Ile Phe Phe Leu Gly Arg Thr Tyr Asp Ala Glu Arg Met 215 220 225 caa caa atg ggc gca gtc aac atc gtg gcc gac cac ggc gac cta gaa 835 Gln Gln Met Gly Ala Val Asn Ile Val Ala Asp His Gly Asp Leu Glu 230 235 240 245 aaa gaa gcc atc caa gca gcc cgc gaa atc aac acc aaa tcc ccc acc 883 Lys Glu Ala Ile Gln Ala Ala Arg Glu Ile Asn Thr Lys Ser Pro Thr 250 255 260 ggg caa cgc atg ctg aaa ttc gcc ttc aat ctc acc gac gat ggc ctc 931 Gly Gln Arg Met Leu Lys Phe Ala Phe Asn Leu Thr Asp Asp Gly Leu 265 270 275 atg gga caa caa gtc ttc gcc ggc gaa gcc acc cgc ctg gcc tac atg 979 Met Gly Gln Gln Val Phe Ala Gly Glu Ala Thr Arg Leu Ala Tyr Met 280 285 290 acg gat gaa gcc gta gag ggt aag gaa gca ttc cta gaa aag cgc gaa 1027 Thr Asp Glu Ala Val Glu Gly Lys Glu Ala Phe Leu Glu Lys Arg Glu 295 300 305 ccc aac tgg aat gaa ttc cct tac tac tac tagtgagttc atggggtcct 1077 Pro Asn Trp Asn Glu Phe Pro Tyr Tyr Tyr 310 315 aaa 1080 <210> 876 <211> 319 <212> PRT <213> Corynebacterium glutamicum <400> 876 Met Ser Asn Tyr Ser Thr Asp Asn Pro Phe Asp Pro Thr Gln Trp Ala 1 5 10 15 Thr Val Pro Gly Phe Glu Glu Phe Thr Asp Ile Thr Tyr His Arg His 20 25 30 Val Gly Thr Thr Arg Ala Asp Gly Ile Val Arg Ile Ala Phe Asp Arg 35 40 45 Pro Glu Val Arg Asn Ala Phe Arg Pro His Thr Val Asp Glu Leu Tyr 50 55 60 Gln Ala Leu Asp His Ala Arg Arg Thr Pro Asp Val Gly Thr Ile Leu 65 70 75 80 Leu Thr Gly Asn Gly Pro Ser Glu Lys Asp Gly Gly Trp Ala Phe Cys 85 90 95 Ser Gly Gly Asp Gln Arg Ile Arg Gly Arg Ser Gly Tyr Gln Tyr Ala 100 105 110 Thr Glu His Ala Arg Asp Asp Ala Thr Ala Asp Val Phe Thr Val Asp 115 120 125 Ile Ala Arg Thr Lys Val Glu Gly Gly Arg Leu His Ile Leu Glu Val 130 135 140 Gln Arg Leu Ile Arg Thr Met Pro Lys Val Val Ile Ala Val Val Asn 145 150 155 160 Gly Trp Ala Ala Gly Gly Gly His Ser Leu His Val Val Cys Asp Leu 165 170 175 Thr Ile Ala Ser Arg Gln Glu Ala Arg Phe Lys Gln Thr Asp Ala Asp 180 185 190 Val Gly Ser Phe Asp Ala Gly Tyr Gly Ser Ala Tyr Leu Ala Lys Met 195 200 205 Val Gly Gln Lys Asn Ala Arg Glu Ile Phe Phe Leu Gly Arg Thr Tyr 210 215 220 Asp Ala Glu Arg Met Gln Gln Met Gly Ala Val Asn Ile Val Ala Asp 225 230 235 240 His Gly Asp Leu Glu Lys Glu Ala Ile Gln Ala Ala Arg Glu Ile Asn 245 250 255 Thr Lys Ser Pro Thr Gly Gln Arg Met Leu Lys Phe Ala Phe Asn Leu 260 265 270 Thr Asp Asp Gly Leu Met Gly Gln Gln Val Phe Ala Gly Glu Ala Thr 275 280 285 Arg Leu Ala Tyr Met Thr Asp Glu Ala Val Glu Gly Lys Glu Ala Phe 290 295 300 Leu Glu Lys Arg Glu Pro Asn Trp Asn Glu Phe Pro Tyr Tyr Tyr 305 310 315 <210> 877 <211> 1017 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(994) <223> RXS00393 <400> 877 tctattcatt tcacaatagc gtttcacact cccccatagc ctgccgaacg tatttcaagc 60 aattgcgcga tcgagtatgt gatggggaaa gatagaggtt atg tct cac acg gaa 115 Met Ser His Thr Glu 1 5 ccc cag ccg aat tct gta act ttg tcc gat tgg att caa ggc gca cgc 163 Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp Ile Gln Gly Ala Arg 10 15 20 ccg cgt acc tgg gca aat gcg ttc gcg cct gtc att gcc ggt tca ggt 211 Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val Ile Ala Gly Ser Gly 25 30 35 gtc gcc gct ttt cat gat ggt ttt gtg tgg tgg aag gcc ttg ctg gcg 259 Val Ala Ala Phe His Asp Gly Phe Val Trp Trp Lys Ala Leu Leu Ala 40 45 50 ctt gtc gtg gcg tgg gct ttg atc atc ggt gtg aat tac gcc aat gat 307 Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val Asn Tyr Ala Asn Asp 55 60 65 tac tct gat ggc att cgt ggc acc gat gaa gac cgc acc ggt cct ctg 355 Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp Arg Thr Gly Pro Leu 70 75 80 85 cga ctc act ggt tct ggg ttg gct gag ccg aag aaa gtg aaa gct gcg 403 Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys Lys Val Lys Ala Ala 90 95 100 gcg ttt att tct ttc ggt atc gca ggt gtc gcc ggc acc gcg ctg agc 451 Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala Gly Thr Ala Leu Ser 105 110 115 ctg ttg agc gcg tgg tgg ctg atc ctc atc ggc atc ctg tgt gtg ctg 499 Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly Ile Leu Cys Val Leu 120 125 130 ggc gcg tgg ttc tac acc ggc ggt aaa aat cct tat ggt tac cgc ggg 547 Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro Tyr Gly Tyr Arg Gly 135 140 145 ctc ggc gag att gct gtg ttc atc ttc ttc ggc ctc gtc gcg gtc atg 595 Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly Leu Val Ala Val Met 150 155 160 165 gga acg cag ttc acc caa acc ggt tcc gtc agc tgg gcc ggt ttg gcc 643 Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser Trp Ala Gly Leu Ala 170 175 180 gcc gca gtt ggc gtg ggg tcg atg tct gct ggc gtg aac ttg gcc aac 691 Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly Val Asn Leu Ala Asn 185 190 195 aat att cgc gat att cca acc gat agc aag acc gga aaa att acc ctc 739 Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr Gly Lys Ile Thr Leu 200 205 210 gcg gtc cgc ctg ggc gat gcg ggt gct cgt aag ctg ttc ctc gcg ctg 787 Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys Leu Phe Leu Ala Leu 215 220 225 att tcc acg ccg ttc atc atg tcc atc tgc ctg gcg ttt gtc gcc tgg 835 Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu Ala Phe Val Ala Trp 230 235 240 245 cca gcg ctg atc gcg atc atc gtt ttc ccg ctg gca ctg aaa gcc gca 883 Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu Ala Leu Lys Ala Ala 250 255 260 ggg ccg atc cgc aac aac gcc acc ggc aag gat ctc atc ccc gtc atc 931 Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp Leu Ile Pro Val Ile 265 270 275 ggc tca aca ggg cgc gcc atg gcg ttg tgg gcc gtg ctc acg ggc ctg 979 Gly Ser Thr Gly Arg Ala Met Ala Leu Trp Ala Val Leu Thr Gly Leu 280 285 290 gca tta gcg ttt agc taaaacgctt ttcgacgctc ccc 1017 Ala Leu Ala Phe Ser 295 <210> 878 <211> 298 <212> PRT <213> Corynebacterium glutamicum <400> 878 Met Ser His Thr Glu Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp 1 5 10 15 Ile Gln Gly Ala Arg Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val 20 25 30 Ile Ala Gly Ser Gly Val Ala Ala Phe His Asp Gly Phe Val Trp Trp 35 40 45 Lys Ala Leu Leu Ala Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val 50 55 60 Asn Tyr Ala Asn Asp Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp 65 70 75 80 Arg Thr Gly Pro Leu Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys 85 90 95 Lys Val Lys Ala Ala Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala 100 105 110 Gly Thr Ala Leu Ser Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly 115 120 125 Ile Leu Cys Val Leu Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro 130 135 140 Tyr Gly Tyr Arg Gly Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly 145 150 155 160 Leu Val Ala Val Met Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser 165 170 175 Trp Ala Gly Leu Ala Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly 180 185 190 Val Asn Leu Ala Asn Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr 195 200 205 Gly Lys Ile Thr Leu Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys 210 215 220 Leu Phe Leu Ala Leu Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu 225 230 235 240 Ala Phe Val Ala Trp Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu 245 250 255 Ala Leu Lys Ala Ala Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp 260 265 270 Leu Ile Pro Val Ile Gly Ser Thr Gly Arg Ala Met Ala Leu Trp Ala 275 280 285 Val Leu Thr Gly Leu Ala Leu Ala Phe Ser 290 295 <210> 879 <211> 1005 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(982) <223> FRXA00393 <400> 879 tctattcatt tcacaatagc gtttcacact cccccatagc ctgccgaacg tatttcaagc 60 aattgcgcga tcgagtatgt gatggggaaa gatagaggtt atg tct cac acg gaa 115 Met Ser His Thr Glu 1 5 ccc cag ccg aat tct gta act ttg tcc gat tgg att caa ggc gca cgc 163 Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp Ile Gln Gly Ala Arg 10 15 20 ccg cgt acc tgg gca aat gcg ttc gcg cct gtc att gcc ggt tca ggt 211 Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val Ile Ala Gly Ser Gly 25 30 35 gtc gcc gct ttt cat gat ggt ttt gtg tgg tgg aag gcc ttg ctg gcg 259 Val Ala Ala Phe His Asp Gly Phe Val Trp Trp Lys Ala Leu Leu Ala 40 45 50 ctt gtc gtg gcg tgg gct ttg atc atc ggt gtg aat tac gcc aat gat 307 Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val Asn Tyr Ala Asn Asp 55 60 65 tac tct gat ggc att cgt ggc acc gat gaa gac cgc acc ggt cct ctg 355 Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp Arg Thr Gly Pro Leu 70 75 80 85 cga ctc act ggt tct ggg ttg gct gag ccg aag aaa gtg aaa gct gcg 403 Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys Lys Val Lys Ala Ala 90 95 100 gcg ttt att tct ttc ggt atc gca ggt gtc gcc ggc acc gcg ctg agc 451 Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala Gly Thr Ala Leu Ser 105 110 115 ctg ttg agc gcg tgg tgg ctg atc ctc atc ggc atc ctg tgt gtg ctg 499 Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly Ile Leu Cys Val Leu 120 125 130 ggc gcg tgg ttc tac acc ggc ggt aaa aat cct tat ggt tac cgc ggg 547 Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro Tyr Gly Tyr Arg Gly 135 140 145 ctc ggc gag att gct gtg ttc atc ttc ttc ggc ctc gtc gcg gtc atg 595 Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly Leu Val Ala Val Met 150 155 160 165 gga acg cag ttc acc caa acc ggt tcc gtc agc tgg gcc ggt ttg gcc 643 Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser Trp Ala Gly Leu Ala 170 175 180 gcc gca gtt ggc gtg ggg tcg atg tct gct ggc gtg aac ttg gcc aac 691 Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly Val Asn Leu Ala Asn 185 190 195 aat att cgc gat att cca acc gat agc aag acc gga aaa att acc ctc 739 Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr Gly Lys Ile Thr Leu 200 205 210 gcg gtc cgc ctg ggc gat gcg ggt gct cgt aag ctg ttc ctc gcg ctg 787 Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys Leu Phe Leu Ala Leu 215 220 225 att tcc acg ccg ttc atc atg tcc atc tgc ctg gcg ttt gtc gcc tgg 835 Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu Ala Phe Val Ala Trp 230 235 240 245 cca gcg ctg atc gcg atc atc gtt ttc ccg ctg gca ctg aaa gcc gca 883 Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu Ala Leu Lys Ala Ala 250 255 260 ggg ccg atc cgc aac aac gcc acc ggc aag gat ctc atc ccg tca tcg 931 Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp Leu Ile Pro Ser Ser 265 270 275 gct caa cag ggc gcg cca tgg cgt tgt ggg ccg tgc tca cgg gcc tgg 979 Ala Gln Gln Gly Ala Pro Trp Arg Cys Gly Pro Cys Ser Arg Ala Trp 280 285 290 cat tagcgtttag ctaaaacgct ttt 1005 His <210> 880 <211> 294 <212> PRT <213> Corynebacterium glutamicum <400> 880 Met Ser His Thr Glu Pro Gln Pro Asn Ser Val Thr Leu Ser Asp Trp 1 5 10 15 Ile Gln Gly Ala Arg Pro Arg Thr Trp Ala Asn Ala Phe Ala Pro Val 20 25 30 Ile Ala Gly Ser Gly Val Ala Ala Phe His Asp Gly Phe Val Trp Trp 35 40 45 Lys Ala Leu Leu Ala Leu Val Val Ala Trp Ala Leu Ile Ile Gly Val 50 55 60 Asn Tyr Ala Asn Asp Tyr Ser Asp Gly Ile Arg Gly Thr Asp Glu Asp 65 70 75 80 Arg Thr Gly Pro Leu Arg Leu Thr Gly Ser Gly Leu Ala Glu Pro Lys 85 90 95 Lys Val Lys Ala Ala Ala Phe Ile Ser Phe Gly Ile Ala Gly Val Ala 100 105 110 Gly Thr Ala Leu Ser Leu Leu Ser Ala Trp Trp Leu Ile Leu Ile Gly 115 120 125 Ile Leu Cys Val Leu Gly Ala Trp Phe Tyr Thr Gly Gly Lys Asn Pro 130 135 140 Tyr Gly Tyr Arg Gly Leu Gly Glu Ile Ala Val Phe Ile Phe Phe Gly 145 150 155 160 Leu Val Ala Val Met Gly Thr Gln Phe Thr Gln Thr Gly Ser Val Ser 165 170 175 Trp Ala Gly Leu Ala Ala Ala Val Gly Val Gly Ser Met Ser Ala Gly 180 185 190 Val Asn Leu Ala Asn Asn Ile Arg Asp Ile Pro Thr Asp Ser Lys Thr 195 200 205 Gly Lys Ile Thr Leu Ala Val Arg Leu Gly Asp Ala Gly Ala Arg Lys 210 215 220 Leu Phe Leu Ala Leu Ile Ser Thr Pro Phe Ile Met Ser Ile Cys Leu 225 230 235 240 Ala Phe Val Ala Trp Pro Ala Leu Ile Ala Ile Ile Val Phe Pro Leu 245 250 255 Ala Leu Lys Ala Ala Gly Pro Ile Arg Asn Asn Ala Thr Gly Lys Asp 260 265 270 Leu Ile Pro Ser Ser Ala Gln Gln Gly Ala Pro Trp Arg Cys Gly Pro 275 280 285 Cys Ser Arg Ala Trp His 290 <210> 881 <211> 843 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(820) <223> RXA00391 <400> 881 atcttgtaga tcccaccgca attctgggag atctcgagga cgcaatctct ggaagaaaac 60 tttcctcccc atccctgtac aagataaaac ccgtgcacag ttg ctg cgc gat tct 115 Leu Leu Arg Asp Ser 1 5 caa cga gtt ggc ctc gcc atc gat cct tcg atc gct ttg gtg atg gcc 163 Gln Arg Val Gly Leu Ala Ile Asp Pro Ser Ile Ala Leu Val Met Ala 10 15 20 act tct ggt tct aca ggt acc ccg aag ggc gct cag ctc act ccg ttg 211 Thr Ser Gly Ser Thr Gly Thr Pro Lys Gly Ala Gln Leu Thr Pro Leu 25 30 35 aat ttg gtg agt tcc gcc gat gct acg cat cag ttt tta ggt ggc gaa 259 Asn Leu Val Ser Ser Ala Asp Ala Thr His Gln Phe Leu Gly Gly Glu 40 45 50 ggc cag tgg ttg ctt gcc atg cca gca cac cac att gca ggc atg cag 307 Gly Gln Trp Leu Leu Ala Met Pro Ala His His Ile Ala Gly Met Gln 55 60 65 gtg ctt ctt cga agc ctc att gct gga gtt gag cca cta gct att gat 355 Val Leu Leu Arg Ser Leu Ile Ala Gly Val Glu Pro Leu Ala Ile Asp 70 75 80 85 ctc agc aca ggt ttt cac att gac gct ttc gca ggc gcc gcg gca gaa 403 Leu Ser Thr Gly Phe His Ile Asp Ala Phe Ala Gly Ala Ala Ala Glu 90 95 100 ctg aaa aat acc ggc gac cgc gtc tat aca tcc ttg act cca atg cag 451 Leu Lys Asn Thr Gly Asp Arg Val Tyr Thr Ser Leu Thr Pro Met Gln 105 110 115 tta ctt aaa gca atg gac tcc ttg caa ggc att gaa gcc ctg aaa ctt 499 Leu Leu Lys Ala Met Asp Ser Leu Gln Gly Ile Glu Ala Leu Lys Leu 120 125 130 ttt gat gtc att ctt gtt ggc ggt gct gca ttg tct aag cag gcc cga 547 Phe Asp Val Ile Leu Val Gly Gly Ala Ala Leu Ser Lys Gln Ala Arg 135 140 145 att tct gcg gag cag cta gac atc aac att gtc acc acc tac ggc tcc 595 Ile Ser Ala Glu Gln Leu Asp Ile Asn Ile Val Thr Thr Tyr Gly Ser 150 155 160 165 tca gag act tca ggt ggc tgc gtt tat gat ggc aag ccc att ccc ggc 643 Ser Glu Thr Ser Gly Gly Cys Val Tyr Asp Gly Lys Pro Ile Pro Gly 170 175 180 gcg aaa gtc cgt att tcg gat gag cgc att gag ttg ggt ggc ccg atg 691 Ala Lys Val Arg Ile Ser Asp Glu Arg Ile Glu Leu Gly Gly Pro Met 185 190 195 att gcg cag ggc tac aga aat gca cct gaa cat ccg gat ttc gcc aac 739 Ile Ala Gln Gly Tyr Arg Asn Ala Pro Glu His Pro Asp Phe Ala Asn 200 205 210 gag ggt tgg ttt acc acc tct gat tca ggt gaa ctc cac gac ggg att 787 Glu Gly Trp Phe Thr Thr Ser Asp Ser Gly Glu Leu His Asp Gly Ile 215 220 225 ctc acc gtg act ggt cgc gtg gat acc cgt cat tgattccggt ggattgaagt 840 Leu Thr Val Thr Gly Arg Val Asp Thr Arg His 230 235 240 tgc 843 <210> 882 <211> 240 <212> PRT <213> Corynebacterium glutamicum <400> 882 Leu Leu Arg Asp Ser Gln Arg Val Gly Leu Ala Ile Asp Pro Ser Ile 1 5 10 15 Ala Leu Val Met Ala Thr Ser Gly Ser Thr Gly Thr Pro Lys Gly Ala 20 25 30 Gln Leu Thr Pro Leu Asn Leu Val Ser Ser Ala Asp Ala Thr His Gln 35 40 45 Phe Leu Gly Gly Glu Gly Gln Trp Leu Leu Ala Met Pro Ala His His 50 55 60 Ile Ala Gly Met Gln Val Leu Leu Arg Ser Leu Ile Ala Gly Val Glu 65 70 75 80 Pro Leu Ala Ile Asp Leu Ser Thr Gly Phe His Ile Asp Ala Phe Ala 85 90 95 Gly Ala Ala Ala Glu Leu Lys Asn Thr Gly Asp Arg Val Tyr Thr Ser 100 105 110 Leu Thr Pro Met Gln Leu Leu Lys Ala Met Asp Ser Leu Gln Gly Ile 115 120 125 Glu Ala Leu Lys Leu Phe Asp Val Ile Leu Val Gly Gly Ala Ala Leu 130 135 140 Ser Lys Gln Ala Arg Ile Ser Ala Glu Gln Leu Asp Ile Asn Ile Val 145 150 155 160 Thr Thr Tyr Gly Ser Ser Glu Thr Ser Gly Gly Cys Val Tyr Asp Gly 165 170 175 Lys Pro Ile Pro Gly Ala Lys Val Arg Ile Ser Asp Glu Arg Ile Glu 180 185 190 Leu Gly Gly Pro Met Ile Ala Gln Gly Tyr Arg Asn Ala Pro Glu His 195 200 205 Pro Asp Phe Ala Asn Glu Gly Trp Phe Thr Thr Ser Asp Ser Gly Glu 210 215 220 Leu His Asp Gly Ile Leu Thr Val Thr Gly Arg Val Asp Thr Arg His 225 230 235 240 <210> 883 <211> 384 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(361) <223> RXS02908 <400> 883 gccaacgagg gttggtttac cacctctgat tcaggtgaac tccacgacgg gattctcacc 60 gtgactggtc gcgtggatac ccgtcattga ttccggtgga ttg aag ttg cac cca 115 Leu Lys Leu His Pro 1 5 gag gta ctg gaa cgt gcc atc gca gat att aaa ggt gtc acc gcg gcg 163 Glu Val Leu Glu Arg Ala Ile Ala Asp Ile Lys Gly Val Thr Ala Ala 10 15 20 tgt gtt gtg ggt att ccc gat ccc cga tta ggc caa gca att gtg gcc 211 Cys Val Val Gly Ile Pro Asp Pro Arg Leu Gly Gln Ala Ile Val Ala 25 30 35 gcg tac tcc gga tcg atc agt ccg tct gaa gtt att gaa ggc ctc gac 259 Ala Tyr Ser Gly Ser Ile Ser Pro Ser Glu Val Ile Glu Gly Leu Asp 40 45 50 gat cta cct cgt tgg cag ctt ccc aaa cgg ctg aag cat ctg gaa tct 307 Asp Leu Pro Arg Trp Gln Leu Pro Lys Arg Leu Lys His Leu Glu Ser 55 60 65 ttg ccc agc att ggt cct gga aaa gct gat cga cgt gct atc gcg aag 355 Leu Pro Ser Ile Gly Pro Gly Lys Ala Asp Arg Arg Ala Ile Ala Lys 70 75 80 85 ctg ttt tagtcttcat tcttgctggc tgc 384 Leu Phe <210> 884 <211> 87 <212> PRT <213> Corynebacterium glutamicum <400> 884 Leu Lys Leu His Pro Glu Val Leu Glu Arg Ala Ile Ala Asp Ile Lys 1 5 10 15 Gly Val Thr Ala Ala Cys Val Val Gly Ile Pro Asp Pro Arg Leu Gly 20 25 30 Gln Ala Ile Val Ala Ala Tyr Ser Gly Ser Ile Ser Pro Ser Glu Val 35 40 45 Ile Glu Gly Leu Asp Asp Leu Pro Arg Trp Gln Leu Pro Lys Arg Leu 50 55 60 Lys His Leu Glu Ser Leu Pro Ser Ile Gly Pro Gly Lys Ala Asp Arg 65 70 75 80 Arg Ala Ile Ala Lys Leu Phe 85 <210> 885 <211> 705 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(682) <223> RXA00997 <400> 885 cccatctgtg gcagatcgaa tgcacccacc gcggagaagt cgtcgcacga accacactgc 60 gcaccatggt gctgaacaag tagccctata ctcgggcacc atg act aca tgg aaa 115 Met Thr Thr Trp Lys 1 5 gag ctc aca gat aac aac cca gcg cac tca gaa aac tac gcg cag cgc 163 Glu Leu Thr Asp Asn Asn Pro Ala His Ser Glu Asn Tyr Ala Gln Arg 10 15 20 tgg cga aac ctc gcc gca gca ggc aat gat att tac ggc gaa gcc cgc 211 Trp Arg Asn Leu Ala Ala Ala Gly Asn Asp Ile Tyr Gly Glu Ala Arg 25 30 35 ctc att gat gcc atg gca ccc agg gga gcg aaa atc ttg gat gct ggc 259 Leu Ile Asp Ala Met Ala Pro Arg Gly Ala Lys Ile Leu Asp Ala Gly 40 45 50 tgc ggc cag gga cgc atc ggt ggc tac ctg tcc aag caa ggc cac gat 307 Cys Gly Gln Gly Arg Ile Gly Gly Tyr Leu Ser Lys Gln Gly His Asp 55 60 65 gtt cta ggc aca gac ctt gat ccc atc ctg att gat tac gcc aag cag 355 Val Leu Gly Thr Asp Leu Asp Pro Ile Leu Ile Asp Tyr Ala Lys Gln 70 75 80 85 gac ttt cca gaa gct cgc tgg gtg gtg gga gat ctc tct gtt gat cag 403 Asp Phe Pro Glu Ala Arg Trp Val Val Gly Asp Leu Ser Val Asp Gln 90 95 100 atc tca gag act gat ttt gat ctc att gtc tcc gcc ggc aac gtc atg 451 Ile Ser Glu Thr Asp Phe Asp Leu Ile Val Ser Ala Gly Asn Val Met 105 110 115 ggc ttt ctc gct gag gat ggt cgc gaa cct gca cta gcc aac att cac 499 Gly Phe Leu Ala Glu Asp Gly Arg Glu Pro Ala Leu Ala Asn Ile His 120 125 130 cgc gca ctg ggc gcc gat ggc cgc gct gtc atc ggt ttc ggc gca gga 547 Arg Ala Leu Gly Ala Asp Gly Arg Ala Val Ile Gly Phe Gly Ala Gly 135 140 145 cgt gga tgg gtc ttt gga gac ttc ctc gaa gtc gca gaa cgc gtg ggc 595 Arg Gly Trp Val Phe Gly Asp Phe Leu Glu Val Ala Glu Arg Val Gly 150 155 160 165 ctc gag ttg gaa aat gct ttt gag tct tgg gat ctt aag cct ttt gtc 643 Leu Glu Leu Glu Asn Ala Phe Glu Ser Trp Asp Leu Lys Pro Phe Val 170 175 180 caa ggc tct gag ttc tta gtg gcg gta ttt acc aag aag taacacctct 692 Gln Gly Ser Glu Phe Leu Val Ala Val Phe Thr Lys Lys 185 190 atcttgcacc tga 705 <210> 886 <211> 194 <212> PRT <213> Corynebacterium glutamicum <400> 886 Met Thr Thr Trp Lys Glu Leu Thr Asp Asn Asn Pro Ala His Ser Glu 1 5 10 15 Asn Tyr Ala Gln Arg Trp Arg Asn Leu Ala Ala Ala Gly Asn Asp Ile 20 25 30 Tyr Gly Glu Ala Arg Leu Ile Asp Ala Met Ala Pro Arg Gly Ala Lys 35 40 45 Ile Leu Asp Ala Gly Cys Gly Gln Gly Arg Ile Gly Gly Tyr Leu Ser 50 55 60 Lys Gln Gly His Asp Val Leu Gly Thr Asp Leu Asp Pro Ile Leu Ile 65 70 75 80 Asp Tyr Ala Lys Gln Asp Phe Pro Glu Ala Arg Trp Val Val Gly Asp 85 90 95 Leu Ser Val Asp Gln Ile Ser Glu Thr Asp Phe Asp Leu Ile Val Ser 100 105 110 Ala Gly Asn Val Met Gly Phe Leu Ala Glu Asp Gly Arg Glu Pro Ala 115 120 125 Leu Ala Asn Ile His Arg Ala Leu Gly Ala Asp Gly Arg Ala Val Ile 130 135 140 Gly Phe Gly Ala Gly Arg Gly Trp Val Phe Gly Asp Phe Leu Glu Val 145 150 155 160 Ala Glu Arg Val Gly Leu Glu Leu Glu Asn Ala Phe Glu Ser Trp Asp 165 170 175 Leu Lys Pro Phe Val Gln Gly Ser Glu Phe Leu Val Ala Val Phe Thr 180 185 190 Lys Lys <210> 887 <211> 861 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(838) <223> RXA02189 <400> 887 aatggcaaaa atgggcacat acgatactga tgggaccaat gggaaaacct caagccacca 60 attgagccag ttctctcaag caaaccgata ctggtgggat gtg gac gcg gcc gac 115 Val Asp Ala Ala Asp 1 5 tat cac gaa cgc cac cct tct tat tta ggc acg gat tcc gct cac ggc 163 Tyr His Glu Arg His Pro Ser Tyr Leu Gly Thr Asp Ser Ala His Gly 10 15 20 gag ttc tac tgg tgc ccc gag atg ctg cat gaa aaa gat gta cgt ctt 211 Glu Phe Tyr Trp Cys Pro Glu Met Leu His Glu Lys Asp Val Arg Leu 25 30 35 ctt ggc act ccc gca gca ctc tcc ggc aag aaa att tta gag atc ggt 259 Leu Gly Thr Pro Ala Ala Leu Ser Gly Lys Lys Ile Leu Glu Ile Gly 40 45 50 tgc ggc tcg gca ccg tgt gct cgg tgg ctg gcc aat gat gtt ccg aat 307 Cys Gly Ser Ala Pro Cys Ala Arg Trp Leu Ala Asn Asp Val Pro Asn 55 60 65 gcc ttt gtc acc gct ttc gac att tct tca caa atg ctc aaa tac gca 355 Ala Phe Val Thr Ala Phe Asp Ile Ser Ser Gln Met Leu Lys Tyr Ala 70 75 80 85 ggt cac gac cat aac gta cac ctc gta cag gcc gat gca atg tca ctc 403 Gly His Asp His Asn Val His Leu Val Gln Ala Asp Ala Met Ser Leu 90 95 100 ccc tac gcc gac agt tcc ttt gac gtg gtc ttt tcc gtt ttc ggc gcc 451 Pro Tyr Ala Asp Ser Ser Phe Asp Val Val Phe Ser Val Phe Gly Ala 105 110 115 atc ccc ttt gtg gag gat tcc gcc gca ctc atg aag gaa atc gcg cgc 499 Ile Pro Phe Val Glu Asp Ser Ala Ala Leu Met Lys Glu Ile Ala Arg 120 125 130 gtc ctc aaa ccc ggc gga cgc ctc att ttc tcc atc acc cac ccg atg 547 Val Leu Lys Pro Gly Gly Arg Leu Ile Phe Ser Ile Thr His Pro Met 135 140 145 cgc tgg att ttc ctc gac gat ccc ggc ccc gca ggc ctc acc gcg atc 595 Arg Trp Ile Phe Leu Asp Asp Pro Gly Pro Ala Gly Leu Thr Ala Ile 150 155 160 165 acc agc tac ttc gac cag cgc ggc tac gtc gaa gaa gac gag gaa acc 643 Thr Ser Tyr Phe Asp Gln Arg Gly Tyr Val Glu Glu Asp Glu Glu Thr 170 175 180 ggt gct tta agc tat gcg gaa cag cac cgc acc atg ggc gcg cgg atc 691 Gly Ala Leu Ser Tyr Ala Glu Gln His Arg Thr Met Gly Ala Arg Ile 185 190 195 aat gag ctt atc gac gcc tcc ctc cac tta gat cac ctc atc gaa cca 739 Asn Glu Leu Ile Asp Ala Ser Leu His Leu Asp His Leu Ile Glu Pro 200 205 210 gaa tgg cca gat gag ttg gaa gaa aac tgg ggc caa tgg tca cca ctt 787 Glu Trp Pro Asp Glu Leu Glu Glu Asn Trp Gly Gln Trp Ser Pro Leu 215 220 225 cga gga aag ctc ttc ccc ggg aca gca atc ttc ctc gcc acg tac cgc 835 Arg Gly Lys Leu Phe Pro Gly Thr Ala Ile Phe Leu Ala Thr Tyr Arg 230 235 240 245 ccc taaaaaacca acggcgctca ttt 861 Pro <210> 888 <211> 246 <212> PRT <213> Corynebacterium glutamicum <400> 888 Val Asp Ala Ala Asp Tyr His Glu Arg His Pro Ser Tyr Leu Gly Thr 1 5 10 15 Asp Ser Ala His Gly Glu Phe Tyr Trp Cys Pro Glu Met Leu His Glu 20 25 30 Lys Asp Val Arg Leu Leu Gly Thr Pro Ala Ala Leu Ser Gly Lys Lys 35 40 45 Ile Leu Glu Ile Gly Cys Gly Ser Ala Pro Cys Ala Arg Trp Leu Ala 50 55 60 Asn Asp Val Pro Asn Ala Phe Val Thr Ala Phe Asp Ile Ser Ser Gln 65 70 75 80 Met Leu Lys Tyr Ala Gly His Asp His Asn Val His Leu Val Gln Ala 85 90 95 Asp Ala Met Ser Leu Pro Tyr Ala Asp Ser Ser Phe Asp Val Val Phe 100 105 110 Ser Val Phe Gly Ala Ile Pro Phe Val Glu Asp Ser Ala Ala Leu Met 115 120 125 Lys Glu Ile Ala Arg Val Leu Lys Pro Gly Gly Arg Leu Ile Phe Ser 130 135 140 Ile Thr His Pro Met Arg Trp Ile Phe Leu Asp Asp Pro Gly Pro Ala 145 150 155 160 Gly Leu Thr Ala Ile Thr Ser Tyr Phe Asp Gln Arg Gly Tyr Val Glu 165 170 175 Glu Asp Glu Glu Thr Gly Ala Leu Ser Tyr Ala Glu Gln His Arg Thr 180 185 190 Met Gly Ala Arg Ile Asn Glu Leu Ile Asp Ala Ser Leu His Leu Asp 195 200 205 His Leu Ile Glu Pro Glu Trp Pro Asp Glu Leu Glu Glu Asn Trp Gly 210 215 220 Gln Trp Ser Pro Leu Arg Gly Lys Leu Phe Pro Gly Thr Ala Ile Phe 225 230 235 240 Leu Ala Thr Tyr Arg Pro 245 <210> 889 <211> 813 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(790) <223> RXA02311 <400> 889 cattttgggt atcggttggt tgtccatcgg tggagctaag ggcgctaagc atcgcagcca 60 aataacctcc cactaaagct cctgggttag actcgaacgc gtg gct aaa gca gat 115 Val Ala Lys Ala Asp 1 5 tta gac aag gac ccc ttc gac gta gcg tca atg ttc gat gac gtc gga 163 Leu Asp Lys Asp Pro Phe Asp Val Ala Ser Met Phe Asp Asp Val Gly 10 15 20 aag aac tac gat ctc acc aat acc gtg ctt tct ttt ggt cag gac cgt 211 Lys Asn Tyr Asp Leu Thr Asn Thr Val Leu Ser Phe Gly Gln Asp Arg 25 30 35 gtg tgg cga aag cgc act agg cag cgc ctg gac ctc aag cca ggg gag 259 Val Trp Arg Lys Arg Thr Arg Gln Arg Leu Asp Leu Lys Pro Gly Glu 40 45 50 aag gtg ctt gat cta gct gca gga aca gcc gtt tcc acc gtg gag ttg 307 Lys Val Leu Asp Leu Ala Ala Gly Thr Ala Val Ser Thr Val Glu Leu 55 60 65 gca aaa tcc ggc gcg ttt tgt gtg gcg tgt gat ttc tcc cag ggc atg 355 Ala Lys Ser Gly Ala Phe Cys Val Ala Cys Asp Phe Ser Gln Gly Met 70 75 80 85 ctc gcc gca ggt aaa gac cgc gat gtg tcc aag gtt gtg ggc gat ggc 403 Leu Ala Ala Gly Lys Asp Arg Asp Val Ser Lys Val Val Gly Asp Gly 90 95 100 atg cag ttg ccg ttt gca gac aac agc ttt gat gct gtg acc att tct 451 Met Gln Leu Pro Phe Ala Asp Asn Ser Phe Asp Ala Val Thr Ile Ser 105 110 115 tat ggt ctg cgc aat att cac gat ttc cgc gct ggc ctg aaa gaa atg 499 Tyr Gly Leu Arg Asn Ile His Asp Phe Arg Ala Gly Leu Lys Glu Met 120 125 130 gcc cgc gtg act aaa cct ggt gga cgc ctc acc gtg gcg gag ttc tcc 547 Ala Arg Val Thr Lys Pro Gly Gly Arg Leu Thr Val Ala Glu Phe Ser 135 140 145 acc ccc gtg atc cct gtg ttc ggc acc gtg tac aag gag tac ctc atg 595 Thr Pro Val Ile Pro Val Phe Gly Thr Val Tyr Lys Glu Tyr Leu Met 150 155 160 165 cgc ctg ctg ccc cag gcg gcg cgc gca gta tcg tcc aac ccg gag gcc 643 Arg Leu Leu Pro Gln Ala Ala Arg Ala Val Ser Ser Asn Pro Glu Ala 170 175 180 tac att tac ctg gct gat tcc atc cgc gca tgg cct agc cag gcg gaa 691 Tyr Ile Tyr Leu Ala Asp Ser Ile Arg Ala Trp Pro Ser Gln Ala Glu 185 190 195 cta gca cgg gag atc aac cag aat ggt tgg tca gat tgc ggt tgg cag 739 Leu Ala Arg Glu Ile Asn Gln Asn Gly Trp Ser Asp Cys Gly Trp Gln 200 205 210 aac ctg acc ttc ggc atc gtc gcg ctg cac tcg gcg att aaa cca gag 787 Asn Leu Thr Phe Gly Ile Val Ala Leu His Ser Ala Ile Lys Pro Glu 215 220 225 aac tagtcgagtc ccacagaggg gag 813 Asn 230 <210> 890 <211> 230 <212> PRT <213> Corynebacterium glutamicum <400> 890 Val Ala Lys Ala Asp Leu Asp Lys Asp Pro Phe Asp Val Ala Ser Met 1 5 10 15 Phe Asp Asp Val Gly Lys Asn Tyr Asp Leu Thr Asn Thr Val Leu Ser 20 25 30 Phe Gly Gln Asp Arg Val Trp Arg Lys Arg Thr Arg Gln Arg Leu Asp 35 40 45 Leu Lys Pro Gly Glu Lys Val Leu Asp Leu Ala Ala Gly Thr Ala Val 50 55 60 Ser Thr Val Glu Leu Ala Lys Ser Gly Ala Phe Cys Val Ala Cys Asp 65 70 75 80 Phe Ser Gln Gly Met Leu Ala Ala Gly Lys Asp Arg Asp Val Ser Lys 85 90 95 Val Val Gly Asp Gly Met Gln Leu Pro Phe Ala Asp Asn Ser Phe Asp 100 105 110 Ala Val Thr Ile Ser Tyr Gly Leu Arg Asn Ile His Asp Phe Arg Ala 115 120 125 Gly Leu Lys Glu Met Ala Arg Val Thr Lys Pro Gly Gly Arg Leu Thr 130 135 140 Val Ala Glu Phe Ser Thr Pro Val Ile Pro Val Phe Gly Thr Val Tyr 145 150 155 160 Lys Glu Tyr Leu Met Arg Leu Leu Pro Gln Ala Ala Arg Ala Val Ser 165 170 175 Ser Asn Pro Glu Ala Tyr Ile Tyr Leu Ala Asp Ser Ile Arg Ala Trp 180 185 190 Pro Ser Gln Ala Glu Leu Ala Arg Glu Ile Asn Gln Asn Gly Trp Ser 195 200 205 Asp Cys Gly Trp Gln Asn Leu Thr Phe Gly Ile Val Ala Leu His Ser 210 215 220 Ala Ile Lys Pro Glu Asn 225 230 <210> 891 <211> 876 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(853) <223> RXN02912 <400> 891 catcggtgtc ggttcactga tggtggccaa gaaggttgga taacagggtt aatcttgggt 60 gatattgaaa tgacgtattc ctgattgggc tgaaaaatct gtg aca tca cct gaa 115 Val Thr Ser Pro Glu 1 5 tta caa aac atc ctt aac aat tat tgg agc ggc agg gca gag gct tac 163 Leu Gln Asn Ile Leu Asn Asn Tyr Trp Ser Gly Arg Ala Glu Ala Tyr 10 15 20 cac ctc aac caa acc caa agc gag cgt gca caa ttt gaa cgc ccc atc 211 His Leu Asn Gln Thr Gln Ser Glu Arg Ala Gln Phe Glu Arg Pro Ile 25 30 35 tgg gaa aag gtg tgg tcg aag gct ttg cct atc gtg tcg gaa gaa gcg 259 Trp Glu Lys Val Trp Ser Lys Ala Leu Pro Ile Val Ser Glu Glu Ala 40 45 50 gta aag gtt ctc gat ctt ggc tgt ggc gct ggt tat gtc acc cac ctt 307 Val Lys Val Leu Asp Leu Gly Cys Gly Ala Gly Tyr Val Thr His Leu 55 60 65 cta agc gat tgc gga tac gaa aca atc ggc gtt gat ggt tct gag gaa 355 Leu Ser Asp Cys Gly Tyr Glu Thr Ile Gly Val Asp Gly Ser Glu Glu 70 75 80 85 atg atc aat caa gct acg cag gag aat ggt ctt cgc agg tcg acg ggt 403 Met Ile Asn Gln Ala Thr Gln Glu Asn Gly Leu Arg Arg Ser Thr Gly 90 95 100 cgg gcg act gcc att ttt cag gtc ggg gat gcg cat gat ccc gag ttc 451 Arg Ala Thr Ala Ile Phe Gln Val Gly Asp Ala His Asp Pro Glu Phe 105 110 115 cgg gaa ggc tct ttt gat gcg ata acc agc cgg tat gtg ttg tgg act 499 Arg Glu Gly Ser Phe Asp Ala Ile Thr Ser Arg Tyr Val Leu Trp Thr 120 125 130 ctg ctg gat ccc cag gca gcg att aat cgt tgg gtg tct ttg cta aaa 547 Leu Leu Asp Pro Gln Ala Ala Ile Asn Arg Trp Val Ser Leu Leu Lys 135 140 145 cct ggt ggg gtt att gcg tgc gta gat gcg gct tgg tat ccg aag ggc 595 Pro Gly Gly Val Ile Ala Cys Val Asp Ala Ala Trp Tyr Pro Lys Gly 150 155 160 165 att gat gct ggc acg gaa gta gat tca gtg gat ggt ccg agt gct ttc 643 Ile Asp Ala Gly Thr Glu Val Asp Ser Val Asp Gly Pro Ser Ala Phe 170 175 180 gta gag acc tat acc ccg gaa ctt ttg agg aat ctt ccc atg tca acg 691 Val Glu Thr Tyr Thr Pro Glu Leu Leu Arg Asn Leu Pro Met Ser Thr 185 190 195 acc tcc act ggc cac aat ttc gca gag ctt ttc cac aac gct ggc ctc 739 Thr Ser Thr Gly His Asn Phe Ala Glu Leu Phe His Asn Ala Gly Leu 200 205 210 aaa gaa gtc aca ttg aca ccc att gag ggg ctg gct gaa ctt gac cag 787 Lys Glu Val Thr Leu Thr Pro Ile Glu Gly Leu Ala Glu Leu Asp Gln 215 220 225 cga ttt ggc ctc tca cca ggg cat gag tcg act ccg cag ttc cta ttc 835 Arg Phe Gly Leu Ser Pro Gly His Glu Ser Thr Pro Gln Phe Leu Phe 230 235 240 245 agg gga att aaa tcc agt tagtgctgtt ttaagcggtc gag 876 Arg Gly Ile Lys Ser Ser 250 <210> 892 <211> 251 <212> PRT <213> Corynebacterium glutamicum <400> 892 Val Thr Ser Pro Glu Leu Gln Asn Ile Leu Asn Asn Tyr Trp Ser Gly 1 5 10 15 Arg Ala Glu Ala Tyr His Leu Asn Gln Thr Gln Ser Glu Arg Ala Gln 20 25 30 Phe Glu Arg Pro Ile Trp Glu Lys Val Trp Ser Lys Ala Leu Pro Ile 35 40 45 Val Ser Glu Glu Ala Val Lys Val Leu Asp Leu Gly Cys Gly Ala Gly 50 55 60 Tyr Val Thr His Leu Leu Ser Asp Cys Gly Tyr Glu Thr Ile Gly Val 65 70 75 80 Asp Gly Ser Glu Glu Met Ile Asn Gln Ala Thr Gln Glu Asn Gly Leu 85 90 95 Arg Arg Ser Thr Gly Arg Ala Thr Ala Ile Phe Gln Val Gly Asp Ala 100 105 110 His Asp Pro Glu Phe Arg Glu Gly Ser Phe Asp Ala Ile Thr Ser Arg 115 120 125 Tyr Val Leu Trp Thr Leu Leu Asp Pro Gln Ala Ala Ile Asn Arg Trp 130 135 140 Val Ser Leu Leu Lys Pro Gly Gly Val Ile Ala Cys Val Asp Ala Ala 145 150 155 160 Trp Tyr Pro Lys Gly Ile Asp Ala Gly Thr Glu Val Asp Ser Val Asp 165 170 175 Gly Pro Ser Ala Phe Val Glu Thr Tyr Thr Pro Glu Leu Leu Arg Asn 180 185 190 Leu Pro Met Ser Thr Thr Ser Thr Gly His Asn Phe Ala Glu Leu Phe 195 200 205 His Asn Ala Gly Leu Lys Glu Val Thr Leu Thr Pro Ile Glu Gly Leu 210 215 220 Ala Glu Leu Asp Gln Arg Phe Gly Leu Ser Pro Gly His Glu Ser Thr 225 230 235 240 Pro Gln Phe Leu Phe Arg Gly Ile Lys Ser Ser 245 250 <210> 893 <211> 585 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(562) <223> RXS00998 <400> 893 aatcggccta aaaggtgtga ccatttgggg gtagtggcga ttttaccagg tcacaggagg 60 tgaaaatcca accattttag gccgactaga gtaattaatt atg act tcc cgc gat 115 Met Thr Ser Arg Asp 1 5 gat caa ccc caa gat ctg ctt tcg ctt gca gaa ctt gcc gcc acc aga 163 Asp Gln Pro Gln Asp Leu Leu Ser Leu Ala Glu Leu Ala Ala Thr Arg 10 15 20 gct tta acc aca gac gaa ctt gaa gca ctc aac aac gcc aat tat ggc 211 Ala Leu Thr Thr Asp Glu Leu Glu Ala Leu Asn Asn Ala Asn Tyr Gly 25 30 35 ctc gac cgc aat ctg ggg ctg cgc tac acc acc atc gag ccc ggc cgg 259 Leu Asp Arg Asn Leu Gly Leu Arg Tyr Thr Thr Ile Glu Pro Gly Arg 40 45 50 gtg gtc agc gaa ctt cac gtg gca tcc aag cac ctg caa gtg gtg ggc 307 Val Val Ser Glu Leu His Val Ala Ser Lys His Leu Gln Val Val Gly 55 60 65 ttg gtc aac ggt ggt gtc tac gcc gcc atc gcc gaa tcc act gga tca 355 Leu Val Asn Gly Gly Val Tyr Ala Ala Ile Ala Glu Ser Thr Gly Ser 70 75 80 85 gtc gcc agc atg att tcc gcc cct gga aaa atg gtc gtc ggc atc aac 403 Val Ala Ser Met Ile Ser Ala Pro Gly Lys Met Val Val Gly Ile Asn 90 95 100 aac aac acc gac ttc att tct gct gtg agc tcc ggt gtc atc gtg gcc 451 Asn Asn Thr Asp Phe Ile Ser Ala Val Ser Ser Gly Val Ile Val Ala 105 110 115 gaa gca acg ccg att cag cta ggt ggc cgc acc cat ctg tgg cag atc 499 Glu Ala Thr Pro Ile Gln Leu Gly Gly Arg Thr His Leu Trp Gln Ile 120 125 130 gaa tgc acc cac cgc gga gaa gtc gtc gca cga acc aca ctg cgc acc 547 Glu Cys Thr His Arg Gly Glu Val Val Ala Arg Thr Thr Leu Arg Thr 135 140 145 atg gtg ctg aac aag tagccctata ctcgggcacc atg 585 Met Val Leu Asn Lys 150 <210> 894 <211> 154 <212> PRT <213> Corynebacterium glutamicum <400> 894 Met Thr Ser Arg Asp Asp Gln Pro Gln Asp Leu Leu Ser Leu Ala Glu 1 5 10 15 Leu Ala Ala Thr Arg Ala Leu Thr Thr Asp Glu Leu Glu Ala Leu Asn 20 25 30 Asn Ala Asn Tyr Gly Leu Asp Arg Asn Leu Gly Leu Arg Tyr Thr Thr 35 40 45 Ile Glu Pro Gly Arg Val Val Ser Glu Leu His Val Ala Ser Lys His 50 55 60 Leu Gln Val Val Gly Leu Val Asn Gly Gly Val Tyr Ala Ala Ile Ala 65 70 75 80 Glu Ser Thr Gly Ser Val Ala Ser Met Ile Ser Ala Pro Gly Lys Met 85 90 95 Val Val Gly Ile Asn Asn Asn Thr Asp Phe Ile Ser Ala Val Ser Ser 100 105 110 Gly Val Ile Val Ala Glu Ala Thr Pro Ile Gln Leu Gly Gly Arg Thr 115 120 125 His Leu Trp Gln Ile Glu Cys Thr His Arg Gly Glu Val Val Ala Arg 130 135 140 Thr Thr Leu Arg Thr Met Val Leu Asn Lys 145 150 <210> 895 <211> 1098 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1075) <223> RXA01215 <400> 895 tcgaaggctg ggtgcaaaag aagcgccctg gaaccgctgc agcacaagcc gcagaagccg 60 cccaaaacgt ccacaaccag gaaggctaag caggatcctc atg act gct cac tgg 115 Met Thr Ala His Trp 1 5 aaa caa aac caa aag aac ctc atg ctg ttt tcg ggt cgt gcg cac cca 163 Lys Gln Asn Gln Lys Asn Leu Met Leu Phe Ser Gly Arg Ala His Pro 10 15 20 gaa ctg gca gaa gct gta gct aaa gag ctc gac gtc aac gtc acc cca 211 Glu Leu Ala Glu Ala Val Ala Lys Glu Leu Asp Val Asn Val Thr Pro 25 30 35 atg acg gca cgc gat ttc gcc aac ggt gaa atc tac gtc cgc ttc gag 259 Met Thr Ala Arg Asp Phe Ala Asn Gly Glu Ile Tyr Val Arg Phe Glu 40 45 50 gaa tca gtt cgt ggc tcc gac tgc ttc gtc ctg cag tcc cac acc cag 307 Glu Ser Val Arg Gly Ser Asp Cys Phe Val Leu Gln Ser His Thr Gln 55 60 65 cct ctc aac aag tgg ctc atg gaa cag ctg ctg atg atc gac gct ttg 355 Pro Leu Asn Lys Trp Leu Met Glu Gln Leu Leu Met Ile Asp Ala Leu 70 75 80 85 aag cgt ggt tcc gca aag cgc atc acc gcg atc ctg ccg ttc tac cca 403 Lys Arg Gly Ser Ala Lys Arg Ile Thr Ala Ile Leu Pro Phe Tyr Pro 90 95 100 tat gcc cgc cag gac aag aag cac cgc ggc cgc gag cca att tct gct 451 Tyr Ala Arg Gln Asp Lys Lys His Arg Gly Arg Glu Pro Ile Ser Ala 105 110 115 cgc ctc atc gcc gac ctc atg ctc acc gct ggc gcg gac cgt atc gtg 499 Arg Leu Ile Ala Asp Leu Met Leu Thr Ala Gly Ala Asp Arg Ile Val 120 125 130 tcc gtg gac ttg cac acc gat cag atc cag ggc ttc ttc gac ggc cca 547 Ser Val Asp Leu His Thr Asp Gln Ile Gln Gly Phe Phe Asp Gly Pro 135 140 145 gtc gat cac atg cac gcc atg ccg atc ctc acc gat cac atc aag gaa 595 Val Asp His Met His Ala Met Pro Ile Leu Thr Asp His Ile Lys Glu 150 155 160 165 aac tac aac ctg gac aac atc tgc gtg gtc tcc cct gac gca ggt cgc 643 Asn Tyr Asn Leu Asp Asn Ile Cys Val Val Ser Pro Asp Ala Gly Arg 170 175 180 gtg aag gtt gca gag aag tgg gct aac acc ttg ggc gat gcc cca atg 691 Val Lys Val Ala Glu Lys Trp Ala Asn Thr Leu Gly Asp Ala Pro Met 185 190 195 gcg ttc gtg cac aag acc cgc tcc acc gag gta gca aac cag gtt gtc 739 Ala Phe Val His Lys Thr Arg Ser Thr Glu Val Ala Asn Gln Val Val 200 205 210 gcc aac cgc gtc gtc ggt gac gtc gac ggc aag gac tgc gtg ctt ctc 787 Ala Asn Arg Val Val Gly Asp Val Asp Gly Lys Asp Cys Val Leu Leu 215 220 225 gac gac atg atc gac act ggc ggc acc atc gcc ggc gct gtg ggc gtc 835 Asp Asp Met Ile Asp Thr Gly Gly Thr Ile Ala Gly Ala Val Gly Val 230 235 240 245 ctg aag aag gct ggc gca aag tca gtc gtc atc gcc tgc acc cac ggt 883 Leu Lys Lys Ala Gly Ala Lys Ser Val Val Ile Ala Cys Thr His Gly 250 255 260 gtg ttc tct gac cca gcc cgc gag cgc ctg tct gca tgc ggt gct gaa 931 Val Phe Ser Asp Pro Ala Arg Glu Arg Leu Ser Ala Cys Gly Ala Glu 265 270 275 gaa gtc atc acc acc gac acc ctg cca cag tcc acc gag ggc tgg agc 979 Glu Val Ile Thr Thr Asp Thr Leu Pro Gln Ser Thr Glu Gly Trp Ser 280 285 290 aac ctg acc gtt ttg tcg atc gca ccg ctg ctg gct cgc acc atc aac 1027 Asn Leu Thr Val Leu Ser Ile Ala Pro Leu Leu Ala Arg Thr Ile Asn 295 300 305 gag atc ttc gaa aac ggt tcc gtc acc acc ctc ttc gag ggc gag gcc 1075 Glu Ile Phe Glu Asn Gly Ser Val Thr Thr Leu Phe Glu Gly Glu Ala 310 315 320 325 taaacaccca tgcccaccac gga 1098 <210> 896 <211> 325 <212> PRT <213> Corynebacterium glutamicum <400> 896 Met Thr Ala His Trp Lys Gln Asn Gln Lys Asn Leu Met Leu Phe Ser 1 5 10 15 Gly Arg Ala His Pro Glu Leu Ala Glu Ala Val Ala Lys Glu Leu Asp 20 25 30 Val Asn Val Thr Pro Met Thr Ala Arg Asp Phe Ala Asn Gly Glu Ile 35 40 45 Tyr Val Arg Phe Glu Glu Ser Val Arg Gly Ser Asp Cys Phe Val Leu 50 55 60 Gln Ser His Thr Gln Pro Leu Asn Lys Trp Leu Met Glu Gln Leu Leu 65 70 75 80 Met Ile Asp Ala Leu Lys Arg Gly Ser Ala Lys Arg Ile Thr Ala Ile 85 90 95 Leu Pro Phe Tyr Pro Tyr Ala Arg Gln Asp Lys Lys His Arg Gly Arg 100 105 110 Glu Pro Ile Ser Ala Arg Leu Ile Ala Asp Leu Met Leu Thr Ala Gly 115 120 125 Ala Asp Arg Ile Val Ser Val Asp Leu His Thr Asp Gln Ile Gln Gly 130 135 140 Phe Phe Asp Gly Pro Val Asp His Met His Ala Met Pro Ile Leu Thr 145 150 155 160 Asp His Ile Lys Glu Asn Tyr Asn Leu Asp Asn Ile Cys Val Val Ser 165 170 175 Pro Asp Ala Gly Arg Val Lys Val Ala Glu Lys Trp Ala Asn Thr Leu 180 185 190 Gly Asp Ala Pro Met Ala Phe Val His Lys Thr Arg Ser Thr Glu Val 195 200 205 Ala Asn Gln Val Val Ala Asn Arg Val Val Gly Asp Val Asp Gly Lys 210 215 220 Asp Cys Val Leu Leu Asp Asp Met Ile Asp Thr Gly Gly Thr Ile Ala 225 230 235 240 Gly Ala Val Gly Val Leu Lys Lys Ala Gly Ala Lys Ser Val Val Ile 245 250 255 Ala Cys Thr His Gly Val Phe Ser Asp Pro Ala Arg Glu Arg Leu Ser 260 265 270 Ala Cys Gly Ala Glu Glu Val Ile Thr Thr Asp Thr Leu Pro Gln Ser 275 280 285 Thr Glu Gly Trp Ser Asn Leu Thr Val Leu Ser Ile Ala Pro Leu Leu 290 295 300 Ala Arg Thr Ile Asn Glu Ile Phe Glu Asn Gly Ser Val Thr Thr Leu 305 310 315 320 Phe Glu Gly Glu Ala 325 <210> 897 <211> 1470 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1447) <223> RXN00558 <400> 897 gaacaggcac cgcaggaaga atgcggcgtt ttcggcgttt gggcgccagg tgaggaagtc 60 tcgaaactta cctactttgg cctcttcgca cttcagcacc gtg gtc aag aag ccc 115 Val Val Lys Lys Pro 1 5 gcg ggc atc gca gta ggc gat ggc gaa cag atc ctg gtt ttc aaa gat 163 Ala Gly Ile Ala Val Gly Asp Gly Glu Gln Ile Leu Val Phe Lys Asp 10 15 20 ttg ggc cta gtc tcc caa gtt ttc gac caa cca att ctg gaa tcc ctc 211 Leu Gly Leu Val Ser Gln Val Phe Asp Gln Pro Ile Leu Glu Ser Leu 25 30 35 cgc gga aac atc gcc atc gga cac acc cga tac acc acc gcc ggc gga 259 Arg Gly Asn Ile Ala Ile Gly His Thr Arg Tyr Thr Thr Ala Gly Gly 40 45 50 aac acc tgg gaa aat gcc cag cct atg ttc cgc atg gca cca gat ggc 307 Asn Thr Trp Glu Asn Ala Gln Pro Met Phe Arg Met Ala Pro Asp Gly 55 60 65 acc gat atc gcc ctt gga cac aac ggc aac ctg att aat tac atc gag 355 Thr Asp Ile Ala Leu Gly His Asn Gly Asn Leu Ile Asn Tyr Ile Glu 70 75 80 85 ttg ttg gac aaa gcc acc gaa ctt ggc ctc gtc gat ccc gcc aag aag 403 Leu Leu Asp Lys Ala Thr Glu Leu Gly Leu Val Asp Pro Ala Lys Lys 90 95 100 cca tca gat acc gat gtg ctc act gga ctg ctc gca agc ggc gtc cat 451 Pro Ser Asp Thr Asp Val Leu Thr Gly Leu Leu Ala Ser Gly Val His 105 110 115 gac gga aat aat ctc ttt gat tcc gcc aag gaa ctc ctc ccc agc gtc 499 Asp Gly Asn Asn Leu Phe Asp Ser Ala Lys Glu Leu Leu Pro Ser Val 120 125 130 aag gga gcc tac tgc ctc acc ttc acc gac gga cac acc ctg tac gca 547 Lys Gly Ala Tyr Cys Leu Thr Phe Thr Asp Gly His Thr Leu Tyr Ala 135 140 145 gcg cgt gat cca ttc ggc atc cgc cca ctg tcc atc ggc cgc ctc gag 595 Ala Arg Asp Pro Phe Gly Ile Arg Pro Leu Ser Ile Gly Arg Leu Glu 150 155 160 165 cgc ggc tgg gta gtc gca tct gaa acc gca gcg ctc gac atc gta ggt 643 Arg Gly Trp Val Val Ala Ser Glu Thr Ala Ala Leu Asp Ile Val Gly 170 175 180 gcc tcg cat gtg cgc gag gtc gaa cca ggc gaa ctg att gct atc gac 691 Ala Ser His Val Arg Glu Val Glu Pro Gly Glu Leu Ile Ala Ile Asp 185 190 195 gaa tcc ggc ctc aag tcc gca cga ttc gcc gag aca acc cgc aaa ggt 739 Glu Ser Gly Leu Lys Ser Ala Arg Phe Ala Glu Thr Thr Arg Lys Gly 200 205 210 tgc gtc ttc gaa tac gtt tac ctg gct cgt cca gac tcc gtg atc aag 787 Cys Val Phe Glu Tyr Val Tyr Leu Ala Arg Pro Asp Ser Val Ile Lys 215 220 225 gga aga aac gtc aac gaa gcc cga ctt gaa atc ggc cgc aag ctc gct 835 Gly Arg Asn Val Asn Glu Ala Arg Leu Glu Ile Gly Arg Lys Leu Ala 230 235 240 245 gca gaa gca cca gca gtc ggc gat cta gtc atc cca acc cca gaa tca 883 Ala Glu Ala Pro Ala Val Gly Asp Leu Val Ile Pro Thr Pro Glu Ser 250 255 260 ggc acc cca gca gca gtt gga ttc gcc caa gca tct ggc atc cca ttc 931 Gly Thr Pro Ala Ala Val Gly Phe Ala Gln Ala Ser Gly Ile Pro Phe 265 270 275 ggc caa ggc atg gtc aaa aac gcc tac gtt ggc cga acc ttc atc cag 979 Gly Gln Gly Met Val Lys Asn Ala Tyr Val Gly Arg Thr Phe Ile Gln 280 285 290 cct tcc gac act ctc cgc caa ctg gga atc cgc ctc aag ctg aac cca 1027 Pro Ser Asp Thr Leu Arg Gln Leu Gly Ile Arg Leu Lys Leu Asn Pro 295 300 305 ttg cgc gag gtt atc gcc gga aag cgc ctt gtg gtt gtg gat gat tcc 1075 Leu Arg Glu Val Ile Ala Gly Lys Arg Leu Val Val Val Asp Asp Ser 310 315 320 325 atc gtc cgc ggt aac acc caa cgc gcc gtg atc cgc atg ttg cgc gaa 1123 Ile Val Arg Gly Asn Thr Gln Arg Ala Val Ile Arg Met Leu Arg Glu 330 335 340 gcc ggt gca gct gag gtt cac gta cgc atc gcc tca cca ccc gtg aaa 1171 Ala Gly Ala Ala Glu Val His Val Arg Ile Ala Ser Pro Pro Val Lys 345 350 355 tgg cca tgc ttc tac ggc atc gat ttt gcc acc cca ggc gaa ctc att 1219 Trp Pro Cys Phe Tyr Gly Ile Asp Phe Ala Thr Pro Gly Glu Leu Ile 360 365 370 gcc aac gct gtc acc agt gac aac gaa gca gaa atg gta gaa gca gtc 1267 Ala Asn Ala Val Thr Ser Asp Asn Glu Ala Glu Met Val Glu Ala Val 375 380 385 cgc tcc gca atc ggc gca gac acc ctc ggc tac gtc tcc atc gac tcc 1315 Arg Ser Ala Ile Gly Ala Asp Thr Leu Gly Tyr Val Ser Ile Asp Ser 390 395 400 405 atg gtt gca gca acc gag caa cca gcc aac gaa ctc tgc atc gcc tgc 1363 Met Val Ala Ala Thr Glu Gln Pro Ala Asn Glu Leu Cys Ile Ala Cys 410 415 420 ttc gac ggc aaa tac ccc atg ggt ctg cca cag gga aac agc aac gca 1411 Phe Asp Gly Lys Tyr Pro Met Gly Leu Pro Gln Gly Asn Ser Asn Ala 425 430 435 gac cta gtc cgc aag atg caa gca acc gcc tca agt taagatcggt 1457 Asp Leu Val Arg Lys Met Gln Ala Thr Ala Ser Ser 440 445 aggcgatagg ggt 1470 <210> 898 <211> 449 <212> PRT <213> Corynebacterium glutamicum <400> 898 Val Val Lys Lys Pro Ala Gly Ile Ala Val Gly Asp Gly Glu Gln Ile 1 5 10 15 Leu Val Phe Lys Asp Leu Gly Leu Val Ser Gln Val Phe Asp Gln Pro 20 25 30 Ile Leu Glu Ser Leu Arg Gly Asn Ile Ala Ile Gly His Thr Arg Tyr 35 40 45 Thr Thr Ala Gly Gly Asn Thr Trp Glu Asn Ala Gln Pro Met Phe Arg 50 55 60 Met Ala Pro Asp Gly Thr Asp Ile Ala Leu Gly His Asn Gly Asn Leu 65 70 75 80 Ile Asn Tyr Ile Glu Leu Leu Asp Lys Ala Thr Glu Leu Gly Leu Val 85 90 95 Asp Pro Ala Lys Lys Pro Ser Asp Thr Asp Val Leu Thr Gly Leu Leu 100 105 110 Ala Ser Gly Val His Asp Gly Asn Asn Leu Phe Asp Ser Ala Lys Glu 115 120 125 Leu Leu Pro Ser Val Lys Gly Ala Tyr Cys Leu Thr Phe Thr Asp Gly 130 135 140 His Thr Leu Tyr Ala Ala Arg Asp Pro Phe Gly Ile Arg Pro Leu Ser 145 150 155 160 Ile Gly Arg Leu Glu Arg Gly Trp Val Val Ala Ser Glu Thr Ala Ala 165 170 175 Leu Asp Ile Val Gly Ala Ser His Val Arg Glu Val Glu Pro Gly Glu 180 185 190 Leu Ile Ala Ile Asp Glu Ser Gly Leu Lys Ser Ala Arg Phe Ala Glu 195 200 205 Thr Thr Arg Lys Gly Cys Val Phe Glu Tyr Val Tyr Leu Ala Arg Pro 210 215 220 Asp Ser Val Ile Lys Gly Arg Asn Val Asn Glu Ala Arg Leu Glu Ile 225 230 235 240 Gly Arg Lys Leu Ala Ala Glu Ala Pro Ala Val Gly Asp Leu Val Ile 245 250 255 Pro Thr Pro Glu Ser Gly Thr Pro Ala Ala Val Gly Phe Ala Gln Ala 260 265 270 Ser Gly Ile Pro Phe Gly Gln Gly Met Val Lys Asn Ala Tyr Val Gly 275 280 285 Arg Thr Phe Ile Gln Pro Ser Asp Thr Leu Arg Gln Leu Gly Ile Arg 290 295 300 Leu Lys Leu Asn Pro Leu Arg Glu Val Ile Ala Gly Lys Arg Leu Val 305 310 315 320 Val Val Asp Asp Ser Ile Val Arg Gly Asn Thr Gln Arg Ala Val Ile 325 330 335 Arg Met Leu Arg Glu Ala Gly Ala Ala Glu Val His Val Arg Ile Ala 340 345 350 Ser Pro Pro Val Lys Trp Pro Cys Phe Tyr Gly Ile Asp Phe Ala Thr 355 360 365 Pro Gly Glu Leu Ile Ala Asn Ala Val Thr Ser Asp Asn Glu Ala Glu 370 375 380 Met Val Glu Ala Val Arg Ser Ala Ile Gly Ala Asp Thr Leu Gly Tyr 385 390 395 400 Val Ser Ile Asp Ser Met Val Ala Ala Thr Glu Gln Pro Ala Asn Glu 405 410 415 Leu Cys Ile Ala Cys Phe Asp Gly Lys Tyr Pro Met Gly Leu Pro Gln 420 425 430 Gly Asn Ser Asn Ala Asp Leu Val Arg Lys Met Gln Ala Thr Ala Ser 435 440 445 Ser <210> 899 <211> 524 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (61)..(501) <223> FRXA00558 <400> 899 gggcgccagg tgaggaagta tcgcagctca cctactttgg cctcttcgca gttcagcacc 60 gtg gtc aag aag ccc gcg ggc atc gca gta ggc gat ggc gaa cag atc 108 Val Val Lys Lys Pro Ala Gly Ile Ala Val Gly Asp Gly Glu Gln Ile 1 5 10 15 ctg gtt ttc aaa gat ttg ggc cta gtc tcc caa gtt ttc gac caa cca 156 Leu Val Phe Lys Asp Leu Gly Leu Val Ser Gln Val Phe Asp Gln Pro 20 25 30 att ctg gaa tcc ctc cgc gga aac atc gcc atc gga cac acc cga tac 204 Ile Leu Glu Ser Leu Arg Gly Asn Ile Ala Ile Gly His Thr Arg Tyr 35 40 45 acc acc gcc ggc gga aac acc tgg gaa aat gcc cag cct atg ttc cgc 252 Thr Thr Ala Gly Gly Asn Thr Trp Glu Asn Ala Gln Pro Met Phe Arg 50 55 60 atg gca cca gat ggc acc gat atc gcc ctt gga cac aac ggc aac ctg 300 Met Ala Pro Asp Gly Thr Asp Ile Ala Leu Gly His Asn Gly Asn Leu 65 70 75 80 att aat tac atc gag ttg ttg gac aaa gcc acc gaa ctt ggc ctc gtc 348 Ile Asn Tyr Ile Glu Leu Leu Asp Lys Ala Thr Glu Leu Gly Leu Val 85 90 95 gat ccc gcc aag aag cca tca gat acc gat gtg ctc act gga ctg ctc 396 Asp Pro Ala Lys Lys Pro Ser Asp Thr Asp Val Leu Thr Gly Leu Leu 100 105 110 gca agc ggc gtc cat gac gga aat aat ctc ttt gat tcc gcc aag gaa 444 Ala Ser Gly Val His Asp Gly Asn Asn Leu Phe Asp Ser Ala Lys Glu 115 120 125 ctc ctc ccc agc gtc aag gga gcc tac tgc ctc acc ttc acc gac gga 492 Leu Leu Pro Ser Val Lys Gly Ala Tyr Cys Leu Thr Phe Thr Asp Gly 130 135 140 cac acc ctg taagcagcgc gtgatccatt cgg 524 His Thr Leu 145 <210> 900 <211> 147 <212> PRT <213> Corynebacterium glutamicum <400> 900 Val Val Lys Lys Pro Ala Gly Ile Ala Val Gly Asp Gly Glu Gln Ile 1 5 10 15 Leu Val Phe Lys Asp Leu Gly Leu Val Ser Gln Val Phe Asp Gln Pro 20 25 30 Ile Leu Glu Ser Leu Arg Gly Asn Ile Ala Ile Gly His Thr Arg Tyr 35 40 45 Thr Thr Ala Gly Gly Asn Thr Trp Glu Asn Ala Gln Pro Met Phe Arg 50 55 60 Met Ala Pro Asp Gly Thr Asp Ile Ala Leu Gly His Asn Gly Asn Leu 65 70 75 80 Ile Asn Tyr Ile Glu Leu Leu Asp Lys Ala Thr Glu Leu Gly Leu Val 85 90 95 Asp Pro Ala Lys Lys Pro Ser Asp Thr Asp Val Leu Thr Gly Leu Leu 100 105 110 Ala Ser Gly Val His Asp Gly Asn Asn Leu Phe Asp Ser Ala Lys Glu 115 120 125 Leu Leu Pro Ser Val Lys Gly Ala Tyr Cys Leu Thr Phe Thr Asp Gly 130 135 140 His Thr Leu 145 <210> 901 <211> 1386 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1363) <223> RXN00626 <400> 901 tcattttaag gcgcttttcg acgccacttt caaccatttc cgaaccgcca agaatactgg 60 aatagcttgg atcaagtttt gcaggataaa ctgtgcaacc atg cgc att ctg gta 115 Met Arg Ile Leu Val 1 5 atc ggc tcg ggc gcc cgt gag cac gcc ctc ctc cgt gga ctg tca act 163 Ile Gly Ser Gly Ala Arg Glu His Ala Leu Leu Arg Gly Leu Ser Thr 10 15 20 gac cct gca acc act gaa ctc cac gtt gcc cca ggt aac gct ggt ctt 211 Asp Pro Ala Thr Thr Glu Leu His Val Ala Pro Gly Asn Ala Gly Leu 25 30 35 gga tcg atc gca act gtc cac cct ggc atc aag gct gat gat cca gag 259 Gly Ser Ile Ala Thr Val His Pro Gly Ile Lys Ala Asp Asp Pro Glu 40 45 50 gct gtc act gcg ttg gct aaa gaa ctg aac tct gat ctg gtt gtt atc 307 Ala Val Thr Ala Leu Ala Lys Glu Leu Asn Ser Asp Leu Val Val Ile 55 60 65 ggc cca gag atc cct ttg gtt gcg ggt gtt gct gat gca ctt cgc gcg 355 Gly Pro Glu Ile Pro Leu Val Ala Gly Val Ala Asp Ala Leu Arg Ala 70 75 80 85 gcg ggt atc gct gtg ttt ggt cct aac aag gac gct gct cgt atc gag 403 Ala Gly Ile Ala Val Phe Gly Pro Asn Lys Asp Ala Ala Arg Ile Glu 90 95 100 ggc tcc aag gct ttc gct aag gat gtc atg gct gcg cag ggt gtt cgt 451 Gly Ser Lys Ala Phe Ala Lys Asp Val Met Ala Ala Gln Gly Val Arg 105 110 115 act gct cat gct gag act att act cct ggt gcg tct tct gaa gat att 499 Thr Ala His Ala Glu Thr Ile Thr Pro Gly Ala Ser Ser Glu Asp Ile 120 125 130 gat gct gcc ata gat cgt ttc ggc cca acg tgg gtt gtc aag gat gat 547 Asp Ala Ala Ile Asp Arg Phe Gly Pro Thr Trp Val Val Lys Asp Asp 135 140 145 ggt ttg tct gcg ggc aag ggt gtt gtg gtt acc ccc gat cgt gca gca 595 Gly Leu Ser Ala Gly Lys Gly Val Val Val Thr Pro Asp Arg Ala Ala 150 155 160 165 gca cgt gct cac gta gat gca gtg ctt gag ggc gga aat cca gtt ttg 643 Ala Arg Ala His Val Asp Ala Val Leu Glu Gly Gly Asn Pro Val Leu 170 175 180 ctg gag tcc ttc ctt gat ggc cct gag gtt tcc ctg ttc tgc ctg gtt 691 Leu Glu Ser Phe Leu Asp Gly Pro Glu Val Ser Leu Phe Cys Leu Val 185 190 195 gat ggc gag acg gta gtt cct ctg ctg cca gcg cag gat cac aag cgt 739 Asp Gly Glu Thr Val Val Pro Leu Leu Pro Ala Gln Asp His Lys Arg 200 205 210 gcg tac gac aac gat gag ggc cca aac act ggt ggc atg ggt gct tat 787 Ala Tyr Asp Asn Asp Glu Gly Pro Asn Thr Gly Gly Met Gly Ala Tyr 215 220 225 gcg ccg ctt cct tgg ctg cct gaa gat ggc gtc cag cgc att gtc gat 835 Ala Pro Leu Pro Trp Leu Pro Glu Asp Gly Val Gln Arg Ile Val Asp 230 235 240 245 gag gtc tgc gtt cct gtt gct cgt gag atg gtg gca cgt ggt tgc gcg 883 Glu Val Cys Val Pro Val Ala Arg Glu Met Val Ala Arg Gly Cys Ala 250 255 260 tac tcc ggt ctg ctt tac gca ggt atc gca tgg ggt gca gaa ggc cct 931 Tyr Ser Gly Leu Leu Tyr Ala Gly Ile Ala Trp Gly Ala Glu Gly Pro 265 270 275 gca gta gtg gag ttc aac tgc cgc ttc ggc gat cca gaa acc cag gct 979 Ala Val Val Glu Phe Asn Cys Arg Phe Gly Asp Pro Glu Thr Gln Ala 280 285 290 gta ctg gca cta ctg aag act cct cta gca gta ctg ctc aac gca gtt 1027 Val Leu Ala Leu Leu Lys Thr Pro Leu Ala Val Leu Leu Asn Ala Val 295 300 305 gct act gga acc ttg gca gag cag cca gca ctg gag tgg gag gat gct 1075 Ala Thr Gly Thr Leu Ala Glu Gln Pro Ala Leu Glu Trp Glu Asp Ala 310 315 320 325 tac gcc ctg act gtg gtg ttg gct tct tac aac tac cca gag gca cct 1123 Tyr Ala Leu Thr Val Val Leu Ala Ser Tyr Asn Tyr Pro Glu Ala Pro 330 335 340 cgt act ggt gat gtc atc cgc aac gct gat gca gat aac gtt ctt cac 1171 Arg Thr Gly Asp Val Ile Arg Asn Ala Asp Ala Asp Asn Val Leu His 345 350 355 gct ggt acc gca ctc aat gct gaa ggc gag ctg gtc tct gcg ggc ggt 1219 Ala Gly Thr Ala Leu Asn Ala Glu Gly Glu Leu Val Ser Ala Gly Gly 360 365 370 cgt gtt ctt aac gtg atc ggt gtg ggt gag acc ctg gag gct gca cgc 1267 Arg Val Leu Asn Val Ile Gly Val Gly Glu Thr Leu Glu Ala Ala Arg 375 380 385 gat aac gcg tac acc acc atc aag gac att gaa ctt gag gga agc cac 1315 Asp Asn Ala Tyr Thr Thr Ile Lys Asp Ile Glu Leu Glu Gly Ser His 390 395 400 405 tac cgc agc gat atc gca ttg gct gca tta gag ggt cgt atc tcg atc 1363 Tyr Arg Ser Asp Ile Ala Leu Ala Ala Leu Glu Gly Arg Ile Ser Ile 410 415 420 taaaagcagt acgcagatag gct 1386 <210> 902 <211> 421 <212> PRT <213> Corynebacterium glutamicum <400> 902 Met Arg Ile Leu Val Ile Gly Ser Gly Ala Arg Glu His Ala Leu Leu 1 5 10 15 Arg Gly Leu Ser Thr Asp Pro Ala Thr Thr Glu Leu His Val Ala Pro 20 25 30 Gly Asn Ala Gly Leu Gly Ser Ile Ala Thr Val His Pro Gly Ile Lys 35 40 45 Ala Asp Asp Pro Glu Ala Val Thr Ala Leu Ala Lys Glu Leu Asn Ser 50 55 60 Asp Leu Val Val Ile Gly Pro Glu Ile Pro Leu Val Ala Gly Val Ala 65 70 75 80 Asp Ala Leu Arg Ala Ala Gly Ile Ala Val Phe Gly Pro Asn Lys Asp 85 90 95 Ala Ala Arg Ile Glu Gly Ser Lys Ala Phe Ala Lys Asp Val Met Ala 100 105 110 Ala Gln Gly Val Arg Thr Ala His Ala Glu Thr Ile Thr Pro Gly Ala 115 120 125 Ser Ser Glu Asp Ile Asp Ala Ala Ile Asp Arg Phe Gly Pro Thr Trp 130 135 140 Val Val Lys Asp Asp Gly Leu Ser Ala Gly Lys Gly Val Val Val Thr 145 150 155 160 Pro Asp Arg Ala Ala Ala Arg Ala His Val Asp Ala Val Leu Glu Gly 165 170 175 Gly Asn Pro Val Leu Leu Glu Ser Phe Leu Asp Gly Pro Glu Val Ser 180 185 190 Leu Phe Cys Leu Val Asp Gly Glu Thr Val Val Pro Leu Leu Pro Ala 195 200 205 Gln Asp His Lys Arg Ala Tyr Asp Asn Asp Glu Gly Pro Asn Thr Gly 210 215 220 Gly Met Gly Ala Tyr Ala Pro Leu Pro Trp Leu Pro Glu Asp Gly Val 225 230 235 240 Gln Arg Ile Val Asp Glu Val Cys Val Pro Val Ala Arg Glu Met Val 245 250 255 Ala Arg Gly Cys Ala Tyr Ser Gly Leu Leu Tyr Ala Gly Ile Ala Trp 260 265 270 Gly Ala Glu Gly Pro Ala Val Val Glu Phe Asn Cys Arg Phe Gly Asp 275 280 285 Pro Glu Thr Gln Ala Val Leu Ala Leu Leu Lys Thr Pro Leu Ala Val 290 295 300 Leu Leu Asn Ala Val Ala Thr Gly Thr Leu Ala Glu Gln Pro Ala Leu 305 310 315 320 Glu Trp Glu Asp Ala Tyr Ala Leu Thr Val Val Leu Ala Ser Tyr Asn 325 330 335 Tyr Pro Glu Ala Pro Arg Thr Gly Asp Val Ile Arg Asn Ala Asp Ala 340 345 350 Asp Asn Val Leu His Ala Gly Thr Ala Leu Asn Ala Glu Gly Glu Leu 355 360 365 Val Ser Ala Gly Gly Arg Val Leu Asn Val Ile Gly Val Gly Glu Thr 370 375 380 Leu Glu Ala Ala Arg Asp Asn Ala Tyr Thr Thr Ile Lys Asp Ile Glu 385 390 395 400 Leu Glu Gly Ser His Tyr Arg Ser Asp Ile Ala Leu Ala Ala Leu Glu 405 410 415 Gly Arg Ile Ser Ile 420 <210> 903 <211> 364 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(364) <223> FRXA00629 <400> 903 tcattttaag gcgcttttcg acgccacttt caaccatttc cgaaccgcca agaatactgg 60 aatagcttgg atcaagtttt gcaggataaa ctgtgcaacc atg cgc att ctg gta 115 Met Arg Ile Leu Val 1 5 atc ggc tcg ggc gcc cgt gag cac gcc ctc ctc cgt gga ctg tca act 163 Ile Gly Ser Gly Ala Arg Glu His Ala Leu Leu Arg Gly Leu Ser Thr 10 15 20 gac cct gca acc act gaa ctc cac gtt gcc cca ggt aac gct ggt ctt 211 Asp Pro Ala Thr Thr Glu Leu His Val Ala Pro Gly Asn Ala Gly Leu 25 30 35 gga tcg atc gca act gtc cac cct ggc atc aag gct gat gat cca gag 259 Gly Ser Ile Ala Thr Val His Pro Gly Ile Lys Ala Asp Asp Pro Glu 40 45 50 gct gtc act gcg ttg gct aaa gaa ctg aac tct gat ctg gtt gtt atc 307 Ala Val Thr Ala Leu Ala Lys Glu Leu Asn Ser Asp Leu Val Val Ile 55 60 65 ggc cca gag atc cct ttg gtt gcg ggt gtt gct gat gca ctt cgc gcg 355 Gly Pro Glu Ile Pro Leu Val Ala Gly Val Ala Asp Ala Leu Arg Ala 70 75 80 85 gcg ggt atc 364 Ala Gly Ile <210> 904 <211> 88 <212> PRT <213> Corynebacterium glutamicum <400> 904 Met Arg Ile Leu Val Ile Gly Ser Gly Ala Arg Glu His Ala Leu Leu 1 5 10 15 Arg Gly Leu Ser Thr Asp Pro Ala Thr Thr Glu Leu His Val Ala Pro 20 25 30 Gly Asn Ala Gly Leu Gly Ser Ile Ala Thr Val His Pro Gly Ile Lys 35 40 45 Ala Asp Asp Pro Glu Ala Val Thr Ala Leu Ala Lys Glu Leu Asn Ser 50 55 60 Asp Leu Val Val Ile Gly Pro Glu Ile Pro Leu Val Ala Gly Val Ala 65 70 75 80 Asp Ala Leu Arg Ala Ala Gly Ile 85 <210> 905 <211> 803 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(780) <223> FRXA00626 <400> 905 gat cgt gca gca gca cgt gct cac gta gat gca gtg ctt gag ggc gga 48 Asp Arg Ala Ala Ala Arg Ala His Val Asp Ala Val Leu Glu Gly Gly 1 5 10 15 aat cca gtt ttg ctg gag tcc ttc ctt gat ggc cct gag gtt tcc ctg 96 Asn Pro Val Leu Leu Glu Ser Phe Leu Asp Gly Pro Glu Val Ser Leu 20 25 30 ttc ttc ctg gtt gat ggc gag acg gta gtt cct ctg ctg cca gcg cag 144 Phe Phe Leu Val Asp Gly Glu Thr Val Val Pro Leu Leu Pro Ala Gln 35 40 45 gat cac aag cgt gcg tac gac aac gat gag ggc cca aac act ggt ggc 192 Asp His Lys Arg Ala Tyr Asp Asn Asp Glu Gly Pro Asn Thr Gly Gly 50 55 60 atg ggt gct tat gcg ccg ctt cct tgg ctg cct gaa gat ggc gtc cag 240 Met Gly Ala Tyr Ala Pro Leu Pro Trp Leu Pro Glu Asp Gly Val Gln 65 70 75 80 cgc att gtc gat gag gtc tgc gtt cct gtt gct cgt gag atg gtg gca 288 Arg Ile Val Asp Glu Val Cys Val Pro Val Ala Arg Glu Met Val Ala 85 90 95 cgt ggt tgc gcg tac tcc ggt ctg ctt tac gca ggt atc gca tgg ggt 336 Arg Gly Cys Ala Tyr Ser Gly Leu Leu Tyr Ala Gly Ile Ala Trp Gly 100 105 110 gca gaa ggc cct gca gta gtg gag ttc aac tgc cgc ttc ggc gat cca 384 Ala Glu Gly Pro Ala Val Val Glu Phe Asn Cys Arg Phe Gly Asp Pro 115 120 125 gaa acc cag gct gta ctg gca cta ctg aag act cct cta gca gta ctg 432 Glu Thr Gln Ala Val Leu Ala Leu Leu Lys Thr Pro Leu Ala Val Leu 130 135 140 ctc aac gca gtt gct act gga acc ttg gca gag cag cca gca ctg gag 480 Leu Asn Ala Val Ala Thr Gly Thr Leu Ala Glu Gln Pro Ala Leu Glu 145 150 155 160 tgg gag gat gct tac gcc ctg act gtg gtg ttg gct tct tac aac tac 528 Trp Glu Asp Ala Tyr Ala Leu Thr Val Val Leu Ala Ser Tyr Asn Tyr 165 170 175 cca gag gca cct cgt act ggt gat gtc atc cgc aac gct gat gca gat 576 Pro Glu Ala Pro Arg Thr Gly Asp Val Ile Arg Asn Ala Asp Ala Asp 180 185 190 aac gtt ctt cac gct ggt acc gca ctc aat gct gaa ggc gag ctg gtc 624 Asn Val Leu His Ala Gly Thr Ala Leu Asn Ala Glu Gly Glu Leu Val 195 200 205 tct gcg ggc ggt cgt gtt ctt aac gtg atc ggt gtg ggt gag acc ctg 672 Ser Ala Gly Gly Arg Val Leu Asn Val Ile Gly Val Gly Glu Thr Leu 210 215 220 gag gct gca cgc gat aac gcg tac acc acc atc aag gac att gaa ctt 720 Glu Ala Ala Arg Asp Asn Ala Tyr Thr Thr Ile Lys Asp Ile Glu Leu 225 230 235 240 gag gga agc cac tac cgc agc gat atc gca ttg gct gca tta gag ggt 768 Glu Gly Ser His Tyr Arg Ser Asp Ile Ala Leu Ala Ala Leu Glu Gly 245 250 255 cgt atc tcg atc taaaagcagt acgcagatag gct 803 Arg Ile Ser Ile 260 <210> 906 <211> 260 <212> PRT <213> Corynebacterium glutamicum <400> 906 Asp Arg Ala Ala Ala Arg Ala His Val Asp Ala Val Leu Glu Gly Gly 1 5 10 15 Asn Pro Val Leu Leu Glu Ser Phe Leu Asp Gly Pro Glu Val Ser Leu 20 25 30 Phe Phe Leu Val Asp Gly Glu Thr Val Val Pro Leu Leu Pro Ala Gln 35 40 45 Asp His Lys Arg Ala Tyr Asp Asn Asp Glu Gly Pro Asn Thr Gly Gly 50 55 60 Met Gly Ala Tyr Ala Pro Leu Pro Trp Leu Pro Glu Asp Gly Val Gln 65 70 75 80 Arg Ile Val Asp Glu Val Cys Val Pro Val Ala Arg Glu Met Val Ala 85 90 95 Arg Gly Cys Ala Tyr Ser Gly Leu Leu Tyr Ala Gly Ile Ala Trp Gly 100 105 110 Ala Glu Gly Pro Ala Val Val Glu Phe Asn Cys Arg Phe Gly Asp Pro 115 120 125 Glu Thr Gln Ala Val Leu Ala Leu Leu Lys Thr Pro Leu Ala Val Leu 130 135 140 Leu Asn Ala Val Ala Thr Gly Thr Leu Ala Glu Gln Pro Ala Leu Glu 145 150 155 160 Trp Glu Asp Ala Tyr Ala Leu Thr Val Val Leu Ala Ser Tyr Asn Tyr 165 170 175 Pro Glu Ala Pro Arg Thr Gly Asp Val Ile Arg Asn Ala Asp Ala Asp 180 185 190 Asn Val Leu His Ala Gly Thr Ala Leu Asn Ala Glu Gly Glu Leu Val 195 200 205 Ser Ala Gly Gly Arg Val Leu Asn Val Ile Gly Val Gly Glu Thr Leu 210 215 220 Glu Ala Ala Arg Asp Asn Ala Tyr Thr Thr Ile Lys Asp Ile Glu Leu 225 230 235 240 Glu Gly Ser His Tyr Arg Ser Asp Ile Ala Leu Ala Ala Leu Glu Gly 245 250 255 Arg Ile Ser Ile 260 <210> 907 <211> 714 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(691) <223> RXA02623 <400> 907 aatcctgaag aggaagaatc cgacgaagaa attgagacag aaactgaggc tgaagaaacc 60 aatgatggtt ccgaggccga agaccgttaa catatctgtt gtg aat tct gac tct 115 Val Asn Ser Asp Ser 1 5 acg acc acc att gtc gtg cta gct tcc gga aca ggc acc ctc ctt cag 163 Thr Thr Thr Ile Val Val Leu Ala Ser Gly Thr Gly Thr Leu Leu Gln 10 15 20 tca ctc att gaa gcg caa ggt acc tat tcg atc gtg ggc gtt gtc tct 211 Ser Leu Ile Glu Ala Gln Gly Thr Tyr Ser Ile Val Gly Val Val Ser 25 30 35 gac gtc gaa tgc cct gca ctt tcc aga gcc gca gat gca ggt att gat 259 Asp Val Glu Cys Pro Ala Leu Ser Arg Ala Ala Asp Ala Gly Ile Asp 40 45 50 act gca gtt gtt ccg ctt gga aaa gat cgt gca cag tgg aac cac gag 307 Thr Ala Val Val Pro Leu Gly Lys Asp Arg Ala Gln Trp Asn His Glu 55 60 65 ctt gca gac gca gtt gca gta agc gac cca gat ttg gtg gtc tct gcg 355 Leu Ala Asp Ala Val Ala Val Ser Asp Pro Asp Leu Val Val Ser Ala 70 75 80 85 gga ttc atg aaa att ttg ggc gaa ggt ttc ctc tca agg ttc ccg tcc 403 Gly Phe Met Lys Ile Leu Gly Glu Gly Phe Leu Ser Arg Phe Pro Ser 90 95 100 cgc atc atc aac acc cac cca gct tta ttg cct tct ttc cct ggt gcc 451 Arg Ile Ile Asn Thr His Pro Ala Leu Leu Pro Ser Phe Pro Gly Ala 105 110 115 cac gcg gtt cgc gat gct ttg gca tac ggt gtg aaa gtg tca ggt tcg 499 His Ala Val Arg Asp Ala Leu Ala Tyr Gly Val Lys Val Ser Gly Ser 120 125 130 aca gtt cac ctt gtc gat gct ggt gtg gat acc ggc cca att att gct 547 Thr Val His Leu Val Asp Ala Gly Val Asp Thr Gly Pro Ile Ile Ala 135 140 145 caa cga gca gtg ccg gta gaa gtg aat gat gat gaa tcc agc ctg cat 595 Gln Arg Ala Val Pro Val Glu Val Asn Asp Asp Glu Ser Ser Leu His 150 155 160 165 gaa aga atc aag cag gtt gag cgt aaa ctc att gta gaa gtc ctg aac 643 Glu Arg Ile Lys Gln Val Glu Arg Lys Leu Ile Val Glu Val Leu Asn 170 175 180 agc gtg gaa ttt tcg cgt cag ggt ggc gta caa ctc aac tgg aga ggc 691 Ser Val Glu Phe Ser Arg Gln Gly Gly Val Gln Leu Asn Trp Arg Gly 185 190 195 taaatccttc atgagcgatg atc 714 <210> 908 <211> 197 <212> PRT <213> Corynebacterium glutamicum <400> 908 Val Asn Ser Asp Ser Thr Thr Thr Ile Val Val Leu Ala Ser Gly Thr 1 5 10 15 Gly Thr Leu Leu Gln Ser Leu Ile Glu Ala Gln Gly Thr Tyr Ser Ile 20 25 30 Val Gly Val Val Ser Asp Val Glu Cys Pro Ala Leu Ser Arg Ala Ala 35 40 45 Asp Ala Gly Ile Asp Thr Ala Val Val Pro Leu Gly Lys Asp Arg Ala 50 55 60 Gln Trp Asn His Glu Leu Ala Asp Ala Val Ala Val Ser Asp Pro Asp 65 70 75 80 Leu Val Val Ser Ala Gly Phe Met Lys Ile Leu Gly Glu Gly Phe Leu 85 90 95 Ser Arg Phe Pro Ser Arg Ile Ile Asn Thr His Pro Ala Leu Leu Pro 100 105 110 Ser Phe Pro Gly Ala His Ala Val Arg Asp Ala Leu Ala Tyr Gly Val 115 120 125 Lys Val Ser Gly Ser Thr Val His Leu Val Asp Ala Gly Val Asp Thr 130 135 140 Gly Pro Ile Ile Ala Gln Arg Ala Val Pro Val Glu Val Asn Asp Asp 145 150 155 160 Glu Ser Ser Leu His Glu Arg Ile Lys Gln Val Glu Arg Lys Leu Ile 165 170 175 Val Glu Val Leu Asn Ser Val Glu Phe Ser Arg Gln Gly Gly Val Gln 180 185 190 Leu Asn Trp Arg Gly 195 <210> 909 <211> 1347 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1324) <223> RXA01442 <400> 909 aattaagcaa cctttttaac aggtttagag ctttcacgag gtggcgtcag ataaagtgaa 60 caccaatatt tctgacatct tccaacggag gctaaaaggc atg tac atc cca gag 115 Met Tyr Ile Pro Glu 1 5 tcg atc ggc acc cct ttg acc ccc aat gcc acg aaa gtg atg ctg ctg 163 Ser Ile Gly Thr Pro Leu Thr Pro Asn Ala Thr Lys Val Met Leu Leu 10 15 20 gga tca gga gaa tta ggc aaa gaa gta gcc atc gct ttc cag cgt ctc 211 Gly Ser Gly Glu Leu Gly Lys Glu Val Ala Ile Ala Phe Gln Arg Leu 25 30 35 ggc ctg gaa gtc cat gca gtt gat cgc tac gaa cat gcc cca gcc cac 259 Gly Leu Glu Val His Ala Val Asp Arg Tyr Glu His Ala Pro Ala His 40 45 50 cag gtc gct cac ttc tcc tat gtc atc gac atg aca gat gca gcc cag 307 Gln Val Ala His Phe Ser Tyr Val Ile Asp Met Thr Asp Ala Ala Gln 55 60 65 gtg cgg gaa ttg gtg gag cgt gtg cgc cca gat ttt gtc att cct gaa 355 Val Arg Glu Leu Val Glu Arg Val Arg Pro Asp Phe Val Ile Pro Glu 70 75 80 85 atc gaa gca ctg gca acc gat gaa ctg gtg aag atc gaa gaa gag ggg 403 Ile Glu Ala Leu Ala Thr Asp Glu Leu Val Lys Ile Glu Glu Glu Gly 90 95 100 cta gct acc atc gtg ccc act gca cgt gca gcc aag ctg acc atg aac 451 Leu Ala Thr Ile Val Pro Thr Ala Arg Ala Ala Lys Leu Thr Met Asn 105 110 115 cgc gaa ggc atc cgc aag ctg gcg gca gag gaa ctg ggt ctt cca acc 499 Arg Glu Gly Ile Arg Lys Leu Ala Ala Glu Glu Leu Gly Leu Pro Thr 120 125 130 tcc aac tat gag ttc tgc tcc act ttc gag gaa ttc tcc gca gct gct 547 Ser Asn Tyr Glu Phe Cys Ser Thr Phe Glu Glu Phe Ser Ala Ala Ala 135 140 145 gaa aag ctt ggt tac ccc aac gtg gtg aaa cca gtg atg agt tct tcc 595 Glu Lys Leu Gly Tyr Pro Asn Val Val Lys Pro Val Met Ser Ser Ser 150 155 160 165 ggc aag ggc caa tct gtt ttg cgt agt tca gac gat ctg cag gca gca 643 Gly Lys Gly Gln Ser Val Leu Arg Ser Ser Asp Asp Leu Gln Ala Ala 170 175 180 tgg gat tat gcg atg agc ggt gca cgc gtg gcc aac tcc cgc gtc atc 691 Trp Asp Tyr Ala Met Ser Gly Ala Arg Val Ala Asn Ser Arg Val Ile 185 190 195 gtg gaa gct ttc gtg gaa ttc gat tac gag atc acc ctg ttg aca gta 739 Val Glu Ala Phe Val Glu Phe Asp Tyr Glu Ile Thr Leu Leu Thr Val 200 205 210 agg tcc atc gat ccc acc acc tct aag cct gcg acc tgg ttc tgt gag 787 Arg Ser Ile Asp Pro Thr Thr Ser Lys Pro Ala Thr Trp Phe Cys Glu 215 220 225 ccc att ggg cac cgc caa gaa gac ggc gac tac gtg gaa tcc tgg cag 835 Pro Ile Gly His Arg Gln Glu Asp Gly Asp Tyr Val Glu Ser Trp Gln 230 235 240 245 cca atg gag atg act cct cgc gcg ctg gaa aac gca cgc tca gta gcc 883 Pro Met Glu Met Thr Pro Arg Ala Leu Glu Asn Ala Arg Ser Val Ala 250 255 260 gca cgc atc acc aac gca ttg ggc gga cgc ggc gta ttt ggt gtg gag 931 Ala Arg Ile Thr Asn Ala Leu Gly Gly Arg Gly Val Phe Gly Val Glu 265 270 275 ctc ttt gtc tcc ggc gat gac gtg tac ttc tct gaa gtc tcc cca cgc 979 Leu Phe Val Ser Gly Asp Asp Val Tyr Phe Ser Glu Val Ser Pro Arg 280 285 290 cca cac gac acc ggc ctt gtc acc ctt gcc acc cag cgt ttc tct gaa 1027 Pro His Asp Thr Gly Leu Val Thr Leu Ala Thr Gln Arg Phe Ser Glu 295 300 305 ttt gaa ctc cac gcc aag gca att ctg gga ttg cct gtt gat gtc acc 1075 Phe Glu Leu His Ala Lys Ala Ile Leu Gly Leu Pro Val Asp Val Thr 310 315 320 325 ctg att tct cca ggt gcc tcc gct gtc atc tac ggt ggc atc gaa tct 1123 Leu Ile Ser Pro Gly Ala Ser Ala Val Ile Tyr Gly Gly Ile Glu Ser 330 335 340 gaa ggc gtg agc tac acc ggg ttg gct gaa gcg ctg gca gtg gct gaa 1171 Glu Gly Val Ser Tyr Thr Gly Leu Ala Glu Ala Leu Ala Val Ala Glu 345 350 355 act gat ctt cgt atc ttt gcc aag cca gag gcc ttc acc aag cgt cgc 1219 Thr Asp Leu Arg Ile Phe Ala Lys Pro Glu Ala Phe Thr Lys Arg Arg 360 365 370 atg ggt gtt gca gtg tcc acc gct gag gat gtg gct gca gcc agg gac 1267 Met Gly Val Ala Val Ser Thr Ala Glu Asp Val Ala Ala Ala Arg Asp 375 380 385 cgc gcc act ttg gct gcc gcg gcg atc aag gtt cat cca gga aat tcc 1315 Arg Ala Thr Leu Ala Ala Ala Ala Ile Lys Val His Pro Gly Asn Ser 390 395 400 405 gca gag gct taacatgctg ggaaagcatc ggg 1347 Ala Glu Ala <210> 910 <211> 408 <212> PRT <213> Corynebacterium glutamicum <400> 910 Met Tyr Ile Pro Glu Ser Ile Gly Thr Pro Leu Thr Pro Asn Ala Thr 1 5 10 15 Lys Val Met Leu Leu Gly Ser Gly Glu Leu Gly Lys Glu Val Ala Ile 20 25 30 Ala Phe Gln Arg Leu Gly Leu Glu Val His Ala Val Asp Arg Tyr Glu 35 40 45 His Ala Pro Ala His Gln Val Ala His Phe Ser Tyr Val Ile Asp Met 50 55 60 Thr Asp Ala Ala Gln Val Arg Glu Leu Val Glu Arg Val Arg Pro Asp 65 70 75 80 Phe Val Ile Pro Glu Ile Glu Ala Leu Ala Thr Asp Glu Leu Val Lys 85 90 95 Ile Glu Glu Glu Gly Leu Ala Thr Ile Val Pro Thr Ala Arg Ala Ala 100 105 110 Lys Leu Thr Met Asn Arg Glu Gly Ile Arg Lys Leu Ala Ala Glu Glu 115 120 125 Leu Gly Leu Pro Thr Ser Asn Tyr Glu Phe Cys Ser Thr Phe Glu Glu 130 135 140 Phe Ser Ala Ala Ala Glu Lys Leu Gly Tyr Pro Asn Val Val Lys Pro 145 150 155 160 Val Met Ser Ser Ser Gly Lys Gly Gln Ser Val Leu Arg Ser Ser Asp 165 170 175 Asp Leu Gln Ala Ala Trp Asp Tyr Ala Met Ser Gly Ala Arg Val Ala 180 185 190 Asn Ser Arg Val Ile Val Glu Ala Phe Val Glu Phe Asp Tyr Glu Ile 195 200 205 Thr Leu Leu Thr Val Arg Ser Ile Asp Pro Thr Thr Ser Lys Pro Ala 210 215 220 Thr Trp Phe Cys Glu Pro Ile Gly His Arg Gln Glu Asp Gly Asp Tyr 225 230 235 240 Val Glu Ser Trp Gln Pro Met Glu Met Thr Pro Arg Ala Leu Glu Asn 245 250 255 Ala Arg Ser Val Ala Ala Arg Ile Thr Asn Ala Leu Gly Gly Arg Gly 260 265 270 Val Phe Gly Val Glu Leu Phe Val Ser Gly Asp Asp Val Tyr Phe Ser 275 280 285 Glu Val Ser Pro Arg Pro His Asp Thr Gly Leu Val Thr Leu Ala Thr 290 295 300 Gln Arg Phe Ser Glu Phe Glu Leu His Ala Lys Ala Ile Leu Gly Leu 305 310 315 320 Pro Val Asp Val Thr Leu Ile Ser Pro Gly Ala Ser Ala Val Ile Tyr 325 330 335 Gly Gly Ile Glu Ser Glu Gly Val Ser Tyr Thr Gly Leu Ala Glu Ala 340 345 350 Leu Ala Val Ala Glu Thr Asp Leu Arg Ile Phe Ala Lys Pro Glu Ala 355 360 365 Phe Thr Lys Arg Arg Met Gly Val Ala Val Ser Thr Ala Glu Asp Val 370 375 380 Ala Ala Ala Arg Asp Arg Ala Thr Leu Ala Ala Ala Ala Ile Lys Val 385 390 395 400 His Pro Gly Asn Ser Ala Glu Ala 405 <210> 911 <211> 2409 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2386) <223> RXN00537 <400> 911 acccggaaca tgccgtcgaa aagctaaccg gcccatctat tgatggcctg gagctgttcc 60 tgtccgccgt tggcaccatc gcggcttaag aggagtaaat atg agc act ttt gtc 115 Met Ser Thr Phe Val 1 5 aat gac acc gtc gaa gac gca atc aag acc cct gag ctg gat cag cca 163 Asn Asp Thr Val Glu Asp Ala Ile Lys Thr Pro Glu Leu Asp Gln Pro 10 15 20 ttt gag gct ctt ggt ctg aaa gac gac gag tac gcg cgc atc aag gaa 211 Phe Glu Ala Leu Gly Leu Lys Asp Asp Glu Tyr Ala Arg Ile Lys Glu 25 30 35 atc ctt ggc cgc cgc cca acc gac gcc gag ctg acc gtt tac tcc gtc 259 Ile Leu Gly Arg Arg Pro Thr Asp Ala Glu Leu Thr Val Tyr Ser Val 40 45 50 atg tgg tcg gag cac tgc tcc tac aag tcc tcc aag gtt cac ctg cgt 307 Met Trp Ser Glu His Cys Ser Tyr Lys Ser Ser Lys Val His Leu Arg 55 60 65 tac ttc ggt gaa acc acc act gag gaa atg gct tcc aag att ctt gcc 355 Tyr Phe Gly Glu Thr Thr Thr Glu Glu Met Ala Ser Lys Ile Leu Ala 70 75 80 85 ggc atc ggc gag aac gct ggt gtg gtc gac atc gga gac ggc aac gcc 403 Gly Ile Gly Glu Asn Ala Gly Val Val Asp Ile Gly Asp Gly Asn Ala 90 95 100 gtg acc ttc cgc gtg gag tcc cac aac cac cca tcc ttc gta gag cca 451 Val Thr Phe Arg Val Glu Ser His Asn His Pro Ser Phe Val Glu Pro 105 110 115 cac cag ggc gct gcg acc ggc gtc ggc ggc atc gtc cgc gac att atg 499 His Gln Gly Ala Ala Thr Gly Val Gly Gly Ile Val Arg Asp Ile Met 120 125 130 gct atg ggc gca cgc cca atc gct gtg atg gat cag ctg cgt ttc ggt 547 Ala Met Gly Ala Arg Pro Ile Ala Val Met Asp Gln Leu Arg Phe Gly 135 140 145 gca ctg gac aac cca gac acc cag cgt gtg ttt cct ggc gtt gtt gac 595 Ala Leu Asp Asn Pro Asp Thr Gln Arg Val Phe Pro Gly Val Val Asp 150 155 160 165 ggc att tcc cat tac ggc aac tgc ctc ggc ctg cca aac atc ggt ggc 643 Gly Ile Ser His Tyr Gly Asn Cys Leu Gly Leu Pro Asn Ile Gly Gly 170 175 180 gaa acc gtc ttc gac gat tcc tac gca ggt aac cca ctg gtc aac gca 691 Glu Thr Val Phe Asp Asp Ser Tyr Ala Gly Asn Pro Leu Val Asn Ala 185 190 195 ctg tgc gtg ggt acc ctc aag gtg gaa gac ctc aag ctt gca ttc gca 739 Leu Cys Val Gly Thr Leu Lys Val Glu Asp Leu Lys Leu Ala Phe Ala 200 205 210 tcc ggc acc ggc aac aag gtg atc ctg ttc ggt tcc cgc acc ggc ctt 787 Ser Gly Thr Gly Asn Lys Val Ile Leu Phe Gly Ser Arg Thr Gly Leu 215 220 225 gat ggc atc ggt ggc gtg tcc gtc ctg ggt tcc gca tcc ttc gaa gaa 835 Asp Gly Ile Gly Gly Val Ser Val Leu Gly Ser Ala Ser Phe Glu Glu 230 235 240 245 ggc gaa gag cgc aag ctc cca gct gtt cag gtt ggc gat cct ttc gca 883 Gly Glu Glu Arg Lys Leu Pro Ala Val Gln Val Gly Asp Pro Phe Ala 250 255 260 gag aag gta ctc atc gag tgc tgc ctc gag ctg tac aag gct ggc gtc 931 Glu Lys Val Leu Ile Glu Cys Cys Leu Glu Leu Tyr Lys Ala Gly Val 265 270 275 gtg gtc ggt att cag gac ctc ggt ggc ggc gga ctt gcg tgt gca acc 979 Val Val Gly Ile Gln Asp Leu Gly Gly Gly Gly Leu Ala Cys Ala Thr 280 285 290 tct gag ctg gca gcc gca ggc gac ggc ggc atg cgc gtc aac cta gac 1027 Ser Glu Leu Ala Ala Ala Gly Asp Gly Gly Met Arg Val Asn Leu Asp 295 300 305 aac gtc cca ctg cgc gca gag aac atg tct gca gct gaa atc ctg gct 1075 Asn Val Pro Leu Arg Ala Glu Asn Met Ser Ala Ala Glu Ile Leu Ala 310 315 320 325 tcc gag tcc cag gag cgc atg tgt gct gtt gtc acc cct gaa aac gtt 1123 Ser Glu Ser Gln Glu Arg Met Cys Ala Val Val Thr Pro Glu Asn Val 330 335 340 gag cgt ttc ctc gag atc tgt gca aag tgg gat gtc acc tgc gca gaa 1171 Glu Arg Phe Leu Glu Ile Cys Ala Lys Trp Asp Val Thr Cys Ala Glu 345 350 355 atc ggc gaa gtt acc gac gag aag gac cgc tac gtt gtg gtc cac aac 1219 Ile Gly Glu Val Thr Asp Glu Lys Asp Arg Tyr Val Val Val His Asn 360 365 370 ggt gaa gtt gtt atc gac gca cct cca tca acc atc gat gaa ggc cct 1267 Gly Glu Val Val Ile Asp Ala Pro Pro Ser Thr Ile Asp Glu Gly Pro 375 380 385 gtc tac aac cgc cca gtt gct cgc cct gag aac cag gac gaa ctg cag 1315 Val Tyr Asn Arg Pro Val Ala Arg Pro Glu Asn Gln Asp Glu Leu Gln 390 395 400 405 ctc gaa ggc gag atc gct cgc cca gtc gac gtt gaa gag atc aag gct 1363 Leu Glu Gly Glu Ile Ala Arg Pro Val Asp Val Glu Glu Ile Lys Ala 410 415 420 gct tgg ctg aag ctt gtc gct tca cca gca ctt gca tcc cgc gcg ttt 1411 Ala Trp Leu Lys Leu Val Ala Ser Pro Ala Leu Ala Ser Arg Ala Phe 425 430 435 atc acc gag cag tac gac cgc tac gtc cgc ggc aac acc gtt cag gca 1459 Ile Thr Glu Gln Tyr Asp Arg Tyr Val Arg Gly Asn Thr Val Gln Ala 440 445 450 aag aac gcc aat gct ggc gtc ttg cgt atc gac gaa gag acc aac cgt 1507 Lys Asn Ala Asn Ala Gly Val Leu Arg Ile Asp Glu Glu Thr Asn Arg 455 460 465 ggc gtt gcg atc tcc gcc gac gca tcc ggc cgt tac acc aag ctc gag 1555 Gly Val Ala Ile Ser Ala Asp Ala Ser Gly Arg Tyr Thr Lys Leu Glu 470 475 480 485 cca aac act ggc gcg cag ctt gca ctg gct gag gct tac cgc aac gtg 1603 Pro Asn Thr Gly Ala Gln Leu Ala Leu Ala Glu Ala Tyr Arg Asn Val 490 495 500 gtc tcc acc ggt gca cgc cca gtg gct gtc acc aac tgc ctg aac ttc 1651 Val Ser Thr Gly Ala Arg Pro Val Ala Val Thr Asn Cys Leu Asn Phe 505 510 515 ggt tcc cca gaa aac gct ggt gtt atg tgg cag ttc aag gaa gca gtc 1699 Gly Ser Pro Glu Asn Ala Gly Val Met Trp Gln Phe Lys Glu Ala Val 520 525 530 cac ggt ctg gca gac gga tcc aag ctt ttg ggc att cca gtg tcc ggc 1747 His Gly Leu Ala Asp Gly Ser Lys Leu Leu Gly Ile Pro Val Ser Gly 535 540 545 ggt aac gtc tcc ttc tac aac cag act ggt gac gag ccc atc ctg cca 1795 Gly Asn Val Ser Phe Tyr Asn Gln Thr Gly Asp Glu Pro Ile Leu Pro 550 555 560 565 acc cca gtc gtg ggt gtt ttg gga gtc ttg gac aac gtc gag cag agc 1843 Thr Pro Val Val Gly Val Leu Gly Val Leu Asp Asn Val Glu Gln Ser 570 575 580 atc ggc aac gtc ctc cca tcc gag gac aac gat ctc tac ctc ctg ggt 1891 Ile Gly Asn Val Leu Pro Ser Glu Asp Asn Asp Leu Tyr Leu Leu Gly 585 590 595 gag acc ttc gat gag ttc ggt ggc tcc atc tgg cag cag gtt tct ggc 1939 Glu Thr Phe Asp Glu Phe Gly Gly Ser Ile Trp Gln Gln Val Ser Gly 600 605 610 gct ggc ctc aac ggt ctg cca cca gta gtt gac ctg ctc aac gag cag 1987 Ala Gly Leu Asn Gly Leu Pro Pro Val Val Asp Leu Leu Asn Glu Gln 615 620 625 cgt ctt gca gac ctg ttc gtc ggt tct gat ctg ttt gct gca tcc cac 2035 Arg Leu Ala Asp Leu Phe Val Gly Ser Asp Leu Phe Ala Ala Ser His 630 635 640 645 gat ctg tct gag ggc ggc ctt ggc cag acc ctc gca gag ctt gcg atc 2083 Asp Leu Ser Glu Gly Gly Leu Gly Gln Thr Leu Ala Glu Leu Ala Ile 650 655 660 cac cag aaa aag gga atg gat gtt gat ctc tcc cag atc cac cca tcc 2131 His Gln Lys Lys Gly Met Asp Val Asp Leu Ser Gln Ile His Pro Ser 665 670 675 ctg ttc acc tca ctg ttt gct gag tcc gct tcc cgc atc gtg gtt gca 2179 Leu Phe Thr Ser Leu Phe Ala Glu Ser Ala Ser Arg Ile Val Val Ala 680 685 690 acc aac cgc ggc gaa gag ttg gaa aag cgc gca gca gag ctg ggt gtt 2227 Thr Asn Arg Gly Glu Glu Leu Glu Lys Arg Ala Ala Glu Leu Gly Val 695 700 705 cca gtg ttc aag ctg ggc tgc acc aac gat tca gcc gtc atc gct gtc 2275 Pro Val Phe Lys Leu Gly Cys Thr Asn Asp Ser Ala Val Ile Ala Val 710 715 720 725 aag ggc gca gac gtt gag ttc act gtt tcc gtg gag gaa ctc cgc gaa 2323 Lys Gly Ala Asp Val Glu Phe Thr Val Ser Val Glu Glu Leu Arg Glu 730 735 740 gca tgg acc aac act ttg cct gag gcc ttc ggt cac gca gtt gga gct 2371 Ala Trp Thr Asn Thr Leu Pro Glu Ala Phe Gly His Ala Val Gly Ala 745 750 755 aac gca gta gtt gca taattttctg ctgtgaagcc ggg 2409 Asn Ala Val Val Ala 760 <210> 912 <211> 762 <212> PRT <213> Corynebacterium glutamicum <400> 912 Met Ser Thr Phe Val Asn Asp Thr Val Glu Asp Ala Ile Lys Thr Pro 1 5 10 15 Glu Leu Asp Gln Pro Phe Glu Ala Leu Gly Leu Lys Asp Asp Glu Tyr 20 25 30 Ala Arg Ile Lys Glu Ile Leu Gly Arg Arg Pro Thr Asp Ala Glu Leu 35 40 45 Thr Val Tyr Ser Val Met Trp Ser Glu His Cys Ser Tyr Lys Ser Ser 50 55 60 Lys Val His Leu Arg Tyr Phe Gly Glu Thr Thr Thr Glu Glu Met Ala 65 70 75 80 Ser Lys Ile Leu Ala Gly Ile Gly Glu Asn Ala Gly Val Val Asp Ile 85 90 95 Gly Asp Gly Asn Ala Val Thr Phe Arg Val Glu Ser His Asn His Pro 100 105 110 Ser Phe Val Glu Pro His Gln Gly Ala Ala Thr Gly Val Gly Gly Ile 115 120 125 Val Arg Asp Ile Met Ala Met Gly Ala Arg Pro Ile Ala Val Met Asp 130 135 140 Gln Leu Arg Phe Gly Ala Leu Asp Asn Pro Asp Thr Gln Arg Val Phe 145 150 155 160 Pro Gly Val Val Asp Gly Ile Ser His Tyr Gly Asn Cys Leu Gly Leu 165 170 175 Pro Asn Ile Gly Gly Glu Thr Val Phe Asp Asp Ser Tyr Ala Gly Asn 180 185 190 Pro Leu Val Asn Ala Leu Cys Val Gly Thr Leu Lys Val Glu Asp Leu 195 200 205 Lys Leu Ala Phe Ala Ser Gly Thr Gly Asn Lys Val Ile Leu Phe Gly 210 215 220 Ser Arg Thr Gly Leu Asp Gly Ile Gly Gly Val Ser Val Leu Gly Ser 225 230 235 240 Ala Ser Phe Glu Glu Gly Glu Glu Arg Lys Leu Pro Ala Val Gln Val 245 250 255 Gly Asp Pro Phe Ala Glu Lys Val Leu Ile Glu Cys Cys Leu Glu Leu 260 265 270 Tyr Lys Ala Gly Val Val Val Gly Ile Gln Asp Leu Gly Gly Gly Gly 275 280 285 Leu Ala Cys Ala Thr Ser Glu Leu Ala Ala Ala Gly Asp Gly Gly Met 290 295 300 Arg Val Asn Leu Asp Asn Val Pro Leu Arg Ala Glu Asn Met Ser Ala 305 310 315 320 Ala Glu Ile Leu Ala Ser Glu Ser Gln Glu Arg Met Cys Ala Val Val 325 330 335 Thr Pro Glu Asn Val Glu Arg Phe Leu Glu Ile Cys Ala Lys Trp Asp 340 345 350 Val Thr Cys Ala Glu Ile Gly Glu Val Thr Asp Glu Lys Asp Arg Tyr 355 360 365 Val Val Val His Asn Gly Glu Val Val Ile Asp Ala Pro Pro Ser Thr 370 375 380 Ile Asp Glu Gly Pro Val Tyr Asn Arg Pro Val Ala Arg Pro Glu Asn 385 390 395 400 Gln Asp Glu Leu Gln Leu Glu Gly Glu Ile Ala Arg Pro Val Asp Val 405 410 415 Glu Glu Ile Lys Ala Ala Trp Leu Lys Leu Val Ala Ser Pro Ala Leu 420 425 430 Ala Ser Arg Ala Phe Ile Thr Glu Gln Tyr Asp Arg Tyr Val Arg Gly 435 440 445 Asn Thr Val Gln Ala Lys Asn Ala Asn Ala Gly Val Leu Arg Ile Asp 450 455 460 Glu Glu Thr Asn Arg Gly Val Ala Ile Ser Ala Asp Ala Ser Gly Arg 465 470 475 480 Tyr Thr Lys Leu Glu Pro Asn Thr Gly Ala Gln Leu Ala Leu Ala Glu 485 490 495 Ala Tyr Arg Asn Val Val Ser Thr Gly Ala Arg Pro Val Ala Val Thr 500 505 510 Asn Cys Leu Asn Phe Gly Ser Pro Glu Asn Ala Gly Val Met Trp Gln 515 520 525 Phe Lys Glu Ala Val His Gly Leu Ala Asp Gly Ser Lys Leu Leu Gly 530 535 540 Ile Pro Val Ser Gly Gly Asn Val Ser Phe Tyr Asn Gln Thr Gly Asp 545 550 555 560 Glu Pro Ile Leu Pro Thr Pro Val Val Gly Val Leu Gly Val Leu Asp 565 570 575 Asn Val Glu Gln Ser Ile Gly Asn Val Leu Pro Ser Glu Asp Asn Asp 580 585 590 Leu Tyr Leu Leu Gly Glu Thr Phe Asp Glu Phe Gly Gly Ser Ile Trp 595 600 605 Gln Gln Val Ser Gly Ala Gly Leu Asn Gly Leu Pro Pro Val Val Asp 610 615 620 Leu Leu Asn Glu Gln Arg Leu Ala Asp Leu Phe Val Gly Ser Asp Leu 625 630 635 640 Phe Ala Ala Ser His Asp Leu Ser Glu Gly Gly Leu Gly Gln Thr Leu 645 650 655 Ala Glu Leu Ala Ile His Gln Lys Lys Gly Met Asp Val Asp Leu Ser 660 665 670 Gln Ile His Pro Ser Leu Phe Thr Ser Leu Phe Ala Glu Ser Ala Ser 675 680 685 Arg Ile Val Val Ala Thr Asn Arg Gly Glu Glu Leu Glu Lys Arg Ala 690 695 700 Ala Glu Leu Gly Val Pro Val Phe Lys Leu Gly Cys Thr Asn Asp Ser 705 710 715 720 Ala Val Ile Ala Val Lys Gly Ala Asp Val Glu Phe Thr Val Ser Val 725 730 735 Glu Glu Leu Arg Glu Ala Trp Thr Asn Thr Leu Pro Glu Ala Phe Gly 740 745 750 His Ala Val Gly Ala Asn Ala Val Val Ala 755 760 <210> 913 <211> 638 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (54)..(638) <223> FRXA02805 <400> 913 tgtgatggat cagctgcgtt tcgggtgcac tggacaaccc agacacccag cgt gtg ttt 59 Val Phe 1 cct ggc gtt gtt gac ggc att tcc cat tac ggc aac tgc ctc ggc ctg 107 Pro Gly Val Val Asp Gly Ile Ser His Tyr Gly Asn Cys Leu Gly Leu 5 10 15 cca aac atc ggt ggc gaa acc gtc ttc gac gat tcc tac gca ggt aac 155 Pro Asn Ile Gly Gly Glu Thr Val Phe Asp Asp Ser Tyr Ala Gly Asn 20 25 30 cca ctg gtc aac gca ctg tgc gtg ggt acc ctc aag gtg gaa gac ctc 203 Pro Leu Val Asn Ala Leu Cys Val Gly Thr Leu Lys Val Glu Asp Leu 35 40 45 50 aag ctt gca ttc gca tcc ggc acc ggc aac aag gtg atc ctg ttc ggt 251 Lys Leu Ala Phe Ala Ser Gly Thr Gly Asn Lys Val Ile Leu Phe Gly 55 60 65 tcc cgc acc ggc ctt gat ggc atc ggt ggc gtg tcc gtc ctg ggt tcc 299 Ser Arg Thr Gly Leu Asp Gly Ile Gly Gly Val Ser Val Leu Gly Ser 70 75 80 gca tcc ttc gaa gaa ggc gaa gag cgc aag ctc cca gct gtt cag gtt 347 Ala Ser Phe Glu Glu Gly Glu Glu Arg Lys Leu Pro Ala Val Gln Val 85 90 95 ggc gat cct ttc gca gag aag gta ctc atc gag tgc tgc ctc gag ctg 395 Gly Asp Pro Phe Ala Glu Lys Val Leu Ile Glu Cys Cys Leu Glu Leu 100 105 110 tac aag gct ggc gtc gtg gtc ggt att cag gac ctc ggt ggc ggc gga 443 Tyr Lys Ala Gly Val Val Val Gly Ile Gln Asp Leu Gly Gly Gly Gly 115 120 125 130 ctt gcg tgt gca acc tct gag ctg gca gcc gca ggc gac ggc ggc atg 491 Leu Ala Cys Ala Thr Ser Glu Leu Ala Ala Ala Gly Asp Gly Gly Met 135 140 145 cgc gtc aac cta gac aac gtc cca ctg cgc gca gag aac atg tct gca 539 Arg Val Asn Leu Asp Asn Val Pro Leu Arg Ala Glu Asn Met Ser Ala 150 155 160 gct gaa atc ctg gct tcc gag tcc cag gag cgc atg tgt gct gtt gtc 587 Ala Glu Ile Leu Ala Ser Glu Ser Gln Glu Arg Met Cys Ala Val Val 165 170 175 acc cct gaa aac gtt gag cgt ttc ctc gag atc tgt gca aag tgg gat 635 Thr Pro Glu Asn Val Glu Arg Phe Leu Glu Ile Cys Ala Lys Trp Asp 180 185 190 gtc 638 Val 195 <210> 914 <211> 195 <212> PRT <213> Corynebacterium glutamicum <400> 914 Val Phe Pro Gly Val Val Asp Gly Ile Ser His Tyr Gly Asn Cys Leu 1 5 10 15 Gly Leu Pro Asn Ile Gly Gly Glu Thr Val Phe Asp Asp Ser Tyr Ala 20 25 30 Gly Asn Pro Leu Val Asn Ala Leu Cys Val Gly Thr Leu Lys Val Glu 35 40 45 Asp Leu Lys Leu Ala Phe Ala Ser Gly Thr Gly Asn Lys Val Ile Leu 50 55 60 Phe Gly Ser Arg Thr Gly Leu Asp Gly Ile Gly Gly Val Ser Val Leu 65 70 75 80 Gly Ser Ala Ser Phe Glu Glu Gly Glu Glu Arg Lys Leu Pro Ala Val 85 90 95 Gln Val Gly Asp Pro Phe Ala Glu Lys Val Leu Ile Glu Cys Cys Leu 100 105 110 Glu Leu Tyr Lys Ala Gly Val Val Val Gly Ile Gln Asp Leu Gly Gly 115 120 125 Gly Gly Leu Ala Cys Ala Thr Ser Glu Leu Ala Ala Ala Gly Asp Gly 130 135 140 Gly Met Arg Val Asn Leu Asp Asn Val Pro Leu Arg Ala Glu Asn Met 145 150 155 160 Ser Ala Ala Glu Ile Leu Ala Ser Glu Ser Gln Glu Arg Met Cys Ala 165 170 175 Val Val Thr Pro Glu Asn Val Glu Arg Phe Leu Glu Ile Cys Ala Lys 180 185 190 Trp Asp Val 195 <210> 915 <211> 697 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (23)..(697) <223> FRXA00537 <220> <221> misc_feature <222> 120 <223> n = a, c, t, or g <220> <221> VARIANT <222> 33 <223> Xaa = Ile, Thr, Asn, or Ser <400> 915 caacagcact tgcatcccgc gc gtg tat cac cga gca gta ctg aac gct acg 52 Val Tyr His Arg Ala Val Leu Asn Ala Thr 1 5 10 tcc gcg gca aca ccg ttc aag caa aag aac gcc aat gct ggc gtc ttg 100 Ser Ala Ala Thr Pro Phe Lys Gln Lys Asn Ala Asn Ala Gly Val Leu 15 20 25 cgt atc gac gaa gag acc anc cgt ggc gtt gcg atc tcc gcc gac gca 148 Arg Ile Asp Glu Glu Thr Xaa Arg Gly Val Ala Ile Ser Ala Asp Ala 30 35 40 tcc ggc cgt tac acc aag ctc gag cca aac act ggc gcg cag ctt gca 196 Ser Gly Arg Tyr Thr Lys Leu Glu Pro Asn Thr Gly Ala Gln Leu Ala 45 50 55 ctg gct gag gct tac cgc aac gtg gtc tcc acc ggt gca cgc cca gtg 244 Leu Ala Glu Ala Tyr Arg Asn Val Val Ser Thr Gly Ala Arg Pro Val 60 65 70 gct gtc acc aac tgc ctg aac ttc ggt tcc cca gaa aac gct ggt gtt 292 Ala Val Thr Asn Cys Leu Asn Phe Gly Ser Pro Glu Asn Ala Gly Val 75 80 85 90 atg tgg cag ttc aag gaa gca gtc cac ggt ctg gca gac gga tcc aag 340 Met Trp Gln Phe Lys Glu Ala Val His Gly Leu Ala Asp Gly Ser Lys 95 100 105 ctt ttg ggc att cca gtg tcc ggc ggt aac gtc tcc ttc tac aac cag 388 Leu Leu Gly Ile Pro Val Ser Gly Gly Asn Val Ser Phe Tyr Asn Gln 110 115 120 act ggt gac gag ccc atc ctg cca acc cca gtc gtg ggt gtt ttg gga 436 Thr Gly Asp Glu Pro Ile Leu Pro Thr Pro Val Val Gly Val Leu Gly 125 130 135 gtc ttg gac aac gtc gag cag agc atc ggc aac gtc ctc cca tcc gag 484 Val Leu Asp Asn Val Glu Gln Ser Ile Gly Asn Val Leu Pro Ser Glu 140 145 150 gac aac gat ctc tac ctc ctg ggt gag acc ttc gat gag ttc ggt ggc 532 Asp Asn Asp Leu Tyr Leu Leu Gly Glu Thr Phe Asp Glu Phe Gly Gly 155 160 165 170 tcc atc tgg cag cag gtt tct ggc gct ggc ctc aac ggt ctg cca cca 580 Ser Ile Trp Gln Gln Val Ser Gly Ala Gly Leu Asn Gly Leu Pro Pro 175 180 185 gta gtt gac ctg ctc aac gag cag cgt ctt gca gac ctg ttc gtc ggt 628 Val Val Asp Leu Leu Asn Glu Gln Arg Leu Ala Asp Leu Phe Val Gly 190 195 200 tct gat ctg ttt gct gca tcc cac gat ctg tct gag ggc ggc ctt ggc 676 Ser Asp Leu Phe Ala Ala Ser His Asp Leu Ser Glu Gly Gly Leu Gly 205 210 215 cag acc ctc gca gag ctt gcg 697 Gln Thr Leu Ala Glu Leu Ala 220 225 <210> 916 <211> 225 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 33 <223> Xaa = Ile, Thr, Asn, or Ser <400> 916 Val Tyr His Arg Ala Val Leu Asn Ala Thr Ser Ala Ala Thr Pro Phe 1 5 10 15 Lys Gln Lys Asn Ala Asn Ala Gly Val Leu Arg Ile Asp Glu Glu Thr 20 25 30 Xaa Arg Gly Val Ala Ile Ser Ala Asp Ala Ser Gly Arg Tyr Thr Lys 35 40 45 Leu Glu Pro Asn Thr Gly Ala Gln Leu Ala Leu Ala Glu Ala Tyr Arg 50 55 60 Asn Val Val Ser Thr Gly Ala Arg Pro Val Ala Val Thr Asn Cys Leu 65 70 75 80 Asn Phe Gly Ser Pro Glu Asn Ala Gly Val Met Trp Gln Phe Lys Glu 85 90 95 Ala Val His Gly Leu Ala Asp Gly Ser Lys Leu Leu Gly Ile Pro Val 100 105 110 Ser Gly Gly Asn Val Ser Phe Tyr Asn Gln Thr Gly Asp Glu Pro Ile 115 120 125 Leu Pro Thr Pro Val Val Gly Val Leu Gly Val Leu Asp Asn Val Glu 130 135 140 Gln Ser Ile Gly Asn Val Leu Pro Ser Glu Asp Asn Asp Leu Tyr Leu 145 150 155 160 Leu Gly Glu Thr Phe Asp Glu Phe Gly Gly Ser Ile Trp Gln Gln Val 165 170 175 Ser Gly Ala Gly Leu Asn Gly Leu Pro Pro Val Val Asp Leu Leu Asn 180 185 190 Glu Gln Arg Leu Ala Asp Leu Phe Val Gly Ser Asp Leu Phe Ala Ala 195 200 205 Ser His Asp Leu Ser Glu Gly Gly Leu Gly Gln Thr Leu Ala Glu Leu 210 215 220 Ala 225 <210> 917 <211> 302 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(279) <223> FRXA00561 <400> 917 ctc ttc cca gat cca ccc atc cct gtt cac ctc act tgt ttg ctg agt 48 Leu Phe Pro Asp Pro Pro Ile Pro Val His Leu Thr Cys Leu Leu Ser 1 5 10 15 ccc gct tcc cgc atc gtg gtt gca acc aac cgc ggc gaa gag ttg gaa 96 Pro Ala Ser Arg Ile Val Val Ala Thr Asn Arg Gly Glu Glu Leu Glu 20 25 30 aag cgc gca gca gag ctg ggt gtt cca gtg ttc aag ctg ggc tgc acc 144 Lys Arg Ala Ala Glu Leu Gly Val Pro Val Phe Lys Leu Gly Cys Thr 35 40 45 aac gat tca gcc gtc atc gct gtc aag ggc gca gac gtt gag ttc act 192 Asn Asp Ser Ala Val Ile Ala Val Lys Gly Ala Asp Val Glu Phe Thr 50 55 60 gtt tcc gtg gag gaa ctc cgc gaa gca tgg acc aac act ttg cct gag 240 Val Ser Val Glu Glu Leu Arg Glu Ala Trp Thr Asn Thr Leu Pro Glu 65 70 75 80 gcc ttc ggt cac gca gtt gga gct aac gca gta gtt gca taattttctg 289 Ala Phe Gly His Ala Val Gly Ala Asn Ala Val Val Ala 85 90 ctgtgaagcc ggg 302 <210> 918 <211> 93 <212> PRT <213> Corynebacterium glutamicum <400> 918 Leu Phe Pro Asp Pro Pro Ile Pro Val His Leu Thr Cys Leu Leu Ser 1 5 10 15 Pro Ala Ser Arg Ile Val Val Ala Thr Asn Arg Gly Glu Glu Leu Glu 20 25 30 Lys Arg Ala Ala Glu Leu Gly Val Pro Val Phe Lys Leu Gly Cys Thr 35 40 45 Asn Asp Ser Ala Val Ile Ala Val Lys Gly Ala Asp Val Glu Phe Thr 50 55 60 Val Ser Val Glu Glu Leu Arg Glu Ala Trp Thr Asn Thr Leu Pro Glu 65 70 75 80 Ala Phe Gly His Ala Val Gly Ala Asn Ala Val Val Ala 85 90 <210> 919 <211> 792 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(769) <223> RXA00541 <400> 919 atgattccgt caccgaagct gacctaaaga aaattgctga aaccctcctc gcaaacaccg 60 tcatcgaaga cttcgatgtg gtgggagttg aggtcgcgaa gtg agc gcc aaa atc 115 Val Ser Ala Lys Ile 1 5 ggt gtc att acc ttc cca ggc acc ctt gac gat gta gat gca gca cgc 163 Gly Val Ile Thr Phe Pro Gly Thr Leu Asp Asp Val Asp Ala Ala Arg 10 15 20 gct gct cgc atc gca ggt gca gaa gta atc agc ctg tgg cac gct gac 211 Ala Ala Arg Ile Ala Gly Ala Glu Val Ile Ser Leu Trp His Ala Asp 25 30 35 gag gat ctc aag ggc gtc gac gca gtt gtc gtt ccc ggt gga ttc tcc 259 Glu Asp Leu Lys Gly Val Asp Ala Val Val Val Pro Gly Gly Phe Ser 40 45 50 tac ggc gat tac ctg cgc acc ggt gca atc tct gca ctg gcg cca gta 307 Tyr Gly Asp Tyr Leu Arg Thr Gly Ala Ile Ser Ala Leu Ala Pro Val 55 60 65 atg cag tcc gtg att gag cag gcc ggt aag ggt atg cca gtc ttg ggc 355 Met Gln Ser Val Ile Glu Gln Ala Gly Lys Gly Met Pro Val Leu Gly 70 75 80 85 att tgc aac ggc ttc cag atc ctc acc gaa gca cgc ctg ctt cca ggc 403 Ile Cys Asn Gly Phe Gln Ile Leu Thr Glu Ala Arg Leu Leu Pro Gly 90 95 100 gcg ctg acc cgc aac aag ggt ctg cac ttt cac tgt gta gac gca cac 451 Ala Leu Thr Arg Asn Lys Gly Leu His Phe His Cys Val Asp Ala His 105 110 115 ctc gtt gta gag aac aac acc act gca tgg acc aac act ttg gaa aag 499 Leu Val Val Glu Asn Asn Thr Thr Ala Trp Thr Asn Thr Leu Glu Lys 120 125 130 ggt cag cag atc ctt att cct gca aag cac ggt gaa ggt cgc ttc cag 547 Gly Gln Gln Ile Leu Ile Pro Ala Lys His Gly Glu Gly Arg Phe Gln 135 140 145 gca gac gca gag acc atc gcc cag ctt gag ggt gaa ggc cgc gtg gtg 595 Ala Asp Ala Glu Thr Ile Ala Gln Leu Glu Gly Glu Gly Arg Val Val 150 155 160 165 ttc cgt tac acc gat aac ttc aac ggt tcc gtc aac gat atc gcc ggt 643 Phe Arg Tyr Thr Asp Asn Phe Asn Gly Ser Val Asn Asp Ile Ala Gly 170 175 180 atc act aat gaa act ggt cgc atc gtc ggt ctc atg ccg cac ccg gaa 691 Ile Thr Asn Glu Thr Gly Arg Ile Val Gly Leu Met Pro His Pro Glu 185 190 195 cat gcc gtc gaa aag cta acc ggc cca tct att gat ggc ctg gag ctg 739 His Ala Val Glu Lys Leu Thr Gly Pro Ser Ile Asp Gly Leu Glu Leu 200 205 210 ttc ctg tcc gcc gtt ggc acc atc gcg gct taagaggagt aaatatgagc 789 Phe Leu Ser Ala Val Gly Thr Ile Ala Ala 215 220 act 792 <210> 920 <211> 223 <212> PRT <213> Corynebacterium glutamicum <400> 920 Val Ser Ala Lys Ile Gly Val Ile Thr Phe Pro Gly Thr Leu Asp Asp 1 5 10 15 Val Asp Ala Ala Arg Ala Ala Arg Ile Ala Gly Ala Glu Val Ile Ser 20 25 30 Leu Trp His Ala Asp Glu Asp Leu Lys Gly Val Asp Ala Val Val Val 35 40 45 Pro Gly Gly Phe Ser Tyr Gly Asp Tyr Leu Arg Thr Gly Ala Ile Ser 50 55 60 Ala Leu Ala Pro Val Met Gln Ser Val Ile Glu Gln Ala Gly Lys Gly 65 70 75 80 Met Pro Val Leu Gly Ile Cys Asn Gly Phe Gln Ile Leu Thr Glu Ala 85 90 95 Arg Leu Leu Pro Gly Ala Leu Thr Arg Asn Lys Gly Leu His Phe His 100 105 110 Cys Val Asp Ala His Leu Val Val Glu Asn Asn Thr Thr Ala Trp Thr 115 120 125 Asn Thr Leu Glu Lys Gly Gln Gln Ile Leu Ile Pro Ala Lys His Gly 130 135 140 Glu Gly Arg Phe Gln Ala Asp Ala Glu Thr Ile Ala Gln Leu Glu Gly 145 150 155 160 Glu Gly Arg Val Val Phe Arg Tyr Thr Asp Asn Phe Asn Gly Ser Val 165 170 175 Asn Asp Ile Ala Gly Ile Thr Asn Glu Thr Gly Arg Ile Val Gly Leu 180 185 190 Met Pro His Pro Glu His Ala Val Glu Lys Leu Thr Gly Pro Ser Ile 195 200 205 Asp Gly Leu Glu Leu Phe Leu Ser Ala Val Gly Thr Ile Ala Ala 210 215 220 <210> 921 <211> 1014 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(991) <223> RXA00620 <400> 921 ggtgatccat gtcaggaagc cagcggtgaa accggcagtg aaaccagcgg tgaatgctaa 60 aattttccga acacacccga ggggtctaga cttgcctaac atg cgt cct gaa ctc 115 Met Arg Pro Glu Leu 1 5 tcc cag tac aag cac ctg tcg gca ggc aag gtc cgt gag atc tac gag 163 Ser Gln Tyr Lys His Leu Ser Ala Gly Lys Val Arg Glu Ile Tyr Glu 10 15 20 atc gac gac aag cac atc ctc atg gtg gct tcc gat cgt atc tct gca 211 Ile Asp Asp Lys His Ile Leu Met Val Ala Ser Asp Arg Ile Ser Ala 25 30 35 tac gat ttc atc ctc gat acc gaa att cca gac aag ggt cga gtg ctc 259 Tyr Asp Phe Ile Leu Asp Thr Glu Ile Pro Asp Lys Gly Arg Val Leu 40 45 50 act gcg atg agc cag ttc ttc ttc gac acc atc gat ttt cct aat cac 307 Thr Ala Met Ser Gln Phe Phe Phe Asp Thr Ile Asp Phe Pro Asn His 55 60 65 ctt gca ggt ccc gct gat gat cca cgt atc cca gaa gaa gtt ttg gga 355 Leu Ala Gly Pro Ala Asp Asp Pro Arg Ile Pro Glu Glu Val Leu Gly 70 75 80 85 cga gca atg gtg tgc aag aag ctc aac atg ctt cct ttt gaa tgc gtg 403 Arg Ala Met Val Cys Lys Lys Leu Asn Met Leu Pro Phe Glu Cys Val 90 95 100 gtt cgt gga tac ctc act ggc tct gga ctt gtt gaa tac aag cag acc 451 Val Arg Gly Tyr Leu Thr Gly Ser Gly Leu Val Glu Tyr Lys Gln Thr 105 110 115 agc tcc gtg tgt gga gtt gag ctc cca gaa ggc ctc gtt gaa tct tct 499 Ser Ser Val Cys Gly Val Glu Leu Pro Glu Gly Leu Val Glu Ser Ser 120 125 130 cag ctg cct gag cca atc ttt acc cca gcc acc aag gct gac atc ggc 547 Gln Leu Pro Glu Pro Ile Phe Thr Pro Ala Thr Lys Ala Asp Ile Gly 135 140 145 gac cac gac atc aat gtc tcc ttt gac gtt gtt gaa gaa cgt ctc ggc 595 Asp His Asp Ile Asn Val Ser Phe Asp Val Val Glu Glu Arg Leu Gly 150 155 160 165 gaa gct cgt gcg aac cag ttg cgc gat gcc tct att gct att tac aag 643 Glu Ala Arg Ala Asn Gln Leu Arg Asp Ala Ser Ile Ala Ile Tyr Lys 170 175 180 gct gct gct gag atc gcc cgt gac cgt ggc gtc atc ctt gcc gac acc 691 Ala Ala Ala Glu Ile Ala Arg Asp Arg Gly Val Ile Leu Ala Asp Thr 185 190 195 aaa ttt gag ttc ggc atc gat gaa gat ggc acc ctc gtg ctt ggt gat 739 Lys Phe Glu Phe Gly Ile Asp Glu Asp Gly Thr Leu Val Leu Gly Asp 200 205 210 gaa gtc ctt acc cca gat tcc tcc cgc tac tgg cct ttg gaa ggc tat 787 Glu Val Leu Thr Pro Asp Ser Ser Arg Tyr Trp Pro Leu Glu Gly Tyr 215 220 225 gaa gca gga tct gtg caa cca agc ttt gat aag caa ttc gtg cgc aac 835 Glu Ala Gly Ser Val Gln Pro Ser Phe Asp Lys Gln Phe Val Arg Asn 230 235 240 245 tgg ctc acc ggc cct aaa tct ggc tgg gac aag gat tcc ggc ttg gag 883 Trp Leu Thr Gly Pro Lys Ser Gly Trp Asp Lys Asp Ser Gly Leu Glu 250 255 260 cca cca gct ctg cca ggt tcc gtt gtt gag gca acc cgc gag cgc tac 931 Pro Pro Ala Leu Pro Gly Ser Val Val Glu Ala Thr Arg Glu Arg Tyr 265 270 275 atc gag gcc tac gag ctg att tct ggt cag aag ttc tgc cag tgg att 979 Ile Glu Ala Tyr Glu Leu Ile Ser Gly Gln Lys Phe Cys Gln Trp Ile 280 285 290 ggt tct tgc gtc taagctgctt gattttccct aaa 1014 Gly Ser Cys Val 295 <210> 922 <211> 297 <212> PRT <213> Corynebacterium glutamicum <400> 922 Met Arg Pro Glu Leu Ser Gln Tyr Lys His Leu Ser Ala Gly Lys Val 1 5 10 15 Arg Glu Ile Tyr Glu Ile Asp Asp Lys His Ile Leu Met Val Ala Ser 20 25 30 Asp Arg Ile Ser Ala Tyr Asp Phe Ile Leu Asp Thr Glu Ile Pro Asp 35 40 45 Lys Gly Arg Val Leu Thr Ala Met Ser Gln Phe Phe Phe Asp Thr Ile 50 55 60 Asp Phe Pro Asn His Leu Ala Gly Pro Ala Asp Asp Pro Arg Ile Pro 65 70 75 80 Glu Glu Val Leu Gly Arg Ala Met Val Cys Lys Lys Leu Asn Met Leu 85 90 95 Pro Phe Glu Cys Val Val Arg Gly Tyr Leu Thr Gly Ser Gly Leu Val 100 105 110 Glu Tyr Lys Gln Thr Ser Ser Val Cys Gly Val Glu Leu Pro Glu Gly 115 120 125 Leu Val Glu Ser Ser Gln Leu Pro Glu Pro Ile Phe Thr Pro Ala Thr 130 135 140 Lys Ala Asp Ile Gly Asp His Asp Ile Asn Val Ser Phe Asp Val Val 145 150 155 160 Glu Glu Arg Leu Gly Glu Ala Arg Ala Asn Gln Leu Arg Asp Ala Ser 165 170 175 Ile Ala Ile Tyr Lys Ala Ala Ala Glu Ile Ala Arg Asp Arg Gly Val 180 185 190 Ile Leu Ala Asp Thr Lys Phe Glu Phe Gly Ile Asp Glu Asp Gly Thr 195 200 205 Leu Val Leu Gly Asp Glu Val Leu Thr Pro Asp Ser Ser Arg Tyr Trp 210 215 220 Pro Leu Glu Gly Tyr Glu Ala Gly Ser Val Gln Pro Ser Phe Asp Lys 225 230 235 240 Gln Phe Val Arg Asn Trp Leu Thr Gly Pro Lys Ser Gly Trp Asp Lys 245 250 255 Asp Ser Gly Leu Glu Pro Pro Ala Leu Pro Gly Ser Val Val Glu Ala 260 265 270 Thr Arg Glu Arg Tyr Ile Glu Ala Tyr Glu Leu Ile Ser Gly Gln Lys 275 280 285 Phe Cys Gln Trp Ile Gly Ser Cys Val 290 295 <210> 923 <211> 1293 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1270) <223> RXN00770 <400> 923 ccatgggtct gccacaggga aacagcaacg cagacctagt ccgcaagatg caagcaaccg 60 cctcaagtta agatcggtag gcgatagggg ttgagcattt ttg ctc tcc ccg tat 115 Leu Leu Ser Pro Tyr 1 5 gcg tgg ggg ttg tcc cgc gca ctt tta gac agt tat gtt cct aat aag 163 Ala Trp Gly Leu Ser Arg Ala Leu Leu Asp Ser Tyr Val Pro Asn Lys 10 15 20 ttc caa acc cca gca gga gaa gcg aag tac acg atg agt gat cac cag 211 Phe Gln Thr Pro Ala Gly Glu Ala Lys Tyr Thr Met Ser Asp His Gln 25 30 35 gac acc acc gcc gaa ggc gtt tca tac gca gca gca gga gtc gac atc 259 Asp Thr Thr Ala Glu Gly Val Ser Tyr Ala Ala Ala Gly Val Asp Ile 40 45 50 gaa gcc ggc gat cgt gcc gtc gaa ctc ttt gca cca atg gcc aag cgc 307 Glu Ala Gly Asp Arg Ala Val Glu Leu Phe Ala Pro Met Ala Lys Arg 55 60 65 gcc acc cgc cca gag gtt ctt ggc aac ctc gga ggc ttc gca gga ctc 355 Ala Thr Arg Pro Glu Val Leu Gly Asn Leu Gly Gly Phe Ala Gly Leu 70 75 80 85 ttt gag ctc gga aaa tac aag aag cca atc ctc gca gca gga tct gac 403 Phe Glu Leu Gly Lys Tyr Lys Lys Pro Ile Leu Ala Ala Gly Ser Asp 90 95 100 gga gtc ggc acc aag ctt gtc atc gcc cag atg atg gac aag cac gac 451 Gly Val Gly Thr Lys Leu Val Ile Ala Gln Met Met Asp Lys His Asp 105 110 115 acc atc ggc atc gac ctt gtt gca atg tgt gtg gat gac ctc gtt gtc 499 Thr Ile Gly Ile Asp Leu Val Ala Met Cys Val Asp Asp Leu Val Val 120 125 130 acc ggc gca gag cca ctg ttc ctc cag gac tac atc gcc atc ggc aag 547 Thr Gly Ala Glu Pro Leu Phe Leu Gln Asp Tyr Ile Ala Ile Gly Lys 135 140 145 gtt gtc cca gag cac gtt gct gag atc gtc tcc ggt atc gca gaa ggc 595 Val Val Pro Glu His Val Ala Glu Ile Val Ser Gly Ile Ala Glu Gly 150 155 160 165 tgt gtc cag gca ggc tgt gct ctg ctc ggt ggc gaa acc gca gaa cac 643 Cys Val Gln Ala Gly Cys Ala Leu Leu Gly Gly Glu Thr Ala Glu His 170 175 180 cca ggt gtt atg gaa cca gac cac tac gat gtc tcc gca act gca gtc 691 Pro Gly Val Met Glu Pro Asp His Tyr Asp Val Ser Ala Thr Ala Val 185 190 195 ggc gtt gtc gaa gca gat gaa ctg cta gga cca gac cgc gtc cgc gca 739 Gly Val Val Glu Ala Asp Glu Leu Leu Gly Pro Asp Arg Val Arg Ala 200 205 210 ggc gac gtc ctc atc ggc atg gct tcc tcc ggt ctg cac tcc aac ggt 787 Gly Asp Val Leu Ile Gly Met Ala Ser Ser Gly Leu His Ser Asn Gly 215 220 225 tac tcc ctg gct cgc cac gtc ctc ctg gaa aag gca ggc ctg gcg ctt 835 Tyr Ser Leu Ala Arg His Val Leu Leu Glu Lys Ala Gly Leu Ala Leu 230 235 240 245 gac gga cac atc gaa gaa ctc gga cgc acc ctc ggt gaa gaa ctt ctc 883 Asp Gly His Ile Glu Glu Leu Gly Arg Thr Leu Gly Glu Glu Leu Leu 250 255 260 gag cca acc cgc atc tac gcc aag gac tgc ctg gca ctg atc gca gag 931 Glu Pro Thr Arg Ile Tyr Ala Lys Asp Cys Leu Ala Leu Ile Ala Glu 265 270 275 tgc gaa gtt cac acc ttc tgc cac gtc acc ggc ggc ggc ctc gca ggc 979 Cys Glu Val His Thr Phe Cys His Val Thr Gly Gly Gly Leu Ala Gly 280 285 290 aac ctc gag cgg gtt gtc cca gaa ggg ctc gtc gca gaa atg tcc cga 1027 Asn Leu Glu Arg Val Val Pro Glu Gly Leu Val Ala Glu Met Ser Arg 295 300 305 gca act tgg acc cca ggc caa atc ttc cgc acc atc tcc tct gtg ggc 1075 Ala Thr Trp Thr Pro Gly Gln Ile Phe Arg Thr Ile Ser Ser Val Gly 310 315 320 325 aag gtt tcc cgc gaa gaa atg gaa aag acc ttc aac atg ggt gtc ggc 1123 Lys Val Ser Arg Glu Glu Met Glu Lys Thr Phe Asn Met Gly Val Gly 330 335 340 atg gtt gca gtc gtt gct gaa aag gac cgc gac cgc gcc ctg gca atg 1171 Met Val Ala Val Val Ala Glu Lys Asp Arg Asp Arg Ala Leu Ala Met 345 350 355 ctc acc gca cgt cac att gac tgc tgg gaa atc gga acc gta cgc aac 1219 Leu Thr Ala Arg His Ile Asp Cys Trp Glu Ile Gly Thr Val Arg Asn 360 365 370 ggt gaa gag gga gag cct cgc gtg atc ctc aac ggc gag cac cct ggc 1267 Gly Glu Glu Gly Glu Pro Arg Val Ile Leu Asn Gly Glu His Pro Gly 375 380 385 tac taagcccaac tgtctgctct aag 1293 Tyr 390 <210> 924 <211> 390 <212> PRT <213> Corynebacterium glutamicum <400> 924 Leu Leu Ser Pro Tyr Ala Trp Gly Leu Ser Arg Ala Leu Leu Asp Ser 1 5 10 15 Tyr Val Pro Asn Lys Phe Gln Thr Pro Ala Gly Glu Ala Lys Tyr Thr 20 25 30 Met Ser Asp His Gln Asp Thr Thr Ala Glu Gly Val Ser Tyr Ala Ala 35 40 45 Ala Gly Val Asp Ile Glu Ala Gly Asp Arg Ala Val Glu Leu Phe Ala 50 55 60 Pro Met Ala Lys Arg Ala Thr Arg Pro Glu Val Leu Gly Asn Leu Gly 65 70 75 80 Gly Phe Ala Gly Leu Phe Glu Leu Gly Lys Tyr Lys Lys Pro Ile Leu 85 90 95 Ala Ala Gly Ser Asp Gly Val Gly Thr Lys Leu Val Ile Ala Gln Met 100 105 110 Met Asp Lys His Asp Thr Ile Gly Ile Asp Leu Val Ala Met Cys Val 115 120 125 Asp Asp Leu Val Val Thr Gly Ala Glu Pro Leu Phe Leu Gln Asp Tyr 130 135 140 Ile Ala Ile Gly Lys Val Val Pro Glu His Val Ala Glu Ile Val Ser 145 150 155 160 Gly Ile Ala Glu Gly Cys Val Gln Ala Gly Cys Ala Leu Leu Gly Gly 165 170 175 Glu Thr Ala Glu His Pro Gly Val Met Glu Pro Asp His Tyr Asp Val 180 185 190 Ser Ala Thr Ala Val Gly Val Val Glu Ala Asp Glu Leu Leu Gly Pro 195 200 205 Asp Arg Val Arg Ala Gly Asp Val Leu Ile Gly Met Ala Ser Ser Gly 210 215 220 Leu His Ser Asn Gly Tyr Ser Leu Ala Arg His Val Leu Leu Glu Lys 225 230 235 240 Ala Gly Leu Ala Leu Asp Gly His Ile Glu Glu Leu Gly Arg Thr Leu 245 250 255 Gly Glu Glu Leu Leu Glu Pro Thr Arg Ile Tyr Ala Lys Asp Cys Leu 260 265 270 Ala Leu Ile Ala Glu Cys Glu Val His Thr Phe Cys His Val Thr Gly 275 280 285 Gly Gly Leu Ala Gly Asn Leu Glu Arg Val Val Pro Glu Gly Leu Val 290 295 300 Ala Glu Met Ser Arg Ala Thr Trp Thr Pro Gly Gln Ile Phe Arg Thr 305 310 315 320 Ile Ser Ser Val Gly Lys Val Ser Arg Glu Glu Met Glu Lys Thr Phe 325 330 335 Asn Met Gly Val Gly Met Val Ala Val Val Ala Glu Lys Asp Arg Asp 340 345 350 Arg Ala Leu Ala Met Leu Thr Ala Arg His Ile Asp Cys Trp Glu Ile 355 360 365 Gly Thr Val Arg Asn Gly Glu Glu Gly Glu Pro Arg Val Ile Leu Asn 370 375 380 Gly Glu His Pro Gly Tyr 385 390 <210> 925 <211> 818 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (15)..(818) <223> FRXA00557 <400> 925 tgggttgagc attt ttg ctc tcc ccg tat gcg tgg ggg ttg tcc cgc gca 50 Leu Leu Ser Pro Tyr Ala Trp Gly Leu Ser Arg Ala 1 5 10 ctt tta gac agt tat gtt cct aat aag ttc caa acc cca gca gga gaa 98 Leu Leu Asp Ser Tyr Val Pro Asn Lys Phe Gln Thr Pro Ala Gly Glu 15 20 25 gcg aag tac acg atg agt gat cac cag gac acc acc gcc gaa ggc gtt 146 Ala Lys Tyr Thr Met Ser Asp His Gln Asp Thr Thr Ala Glu Gly Val 30 35 40 tca tac gca gca gca gga gtc gac atc gaa gcc ggc gat cgt gcc gtc 194 Ser Tyr Ala Ala Ala Gly Val Asp Ile Glu Ala Gly Asp Arg Ala Val 45 50 55 60 gaa ctc ttt gca cca atg gcc aag cgc gcc acc cgc cca gag gtt ctt 242 Glu Leu Phe Ala Pro Met Ala Lys Arg Ala Thr Arg Pro Glu Val Leu 65 70 75 ggc aac ctc gga ggc ttc gca gga ctc ttt gag ctc gga aaa tac aag 290 Gly Asn Leu Gly Gly Phe Ala Gly Leu Phe Glu Leu Gly Lys Tyr Lys 80 85 90 aag cca atc ctc gca gca gga tct gac gga gtc ggc acc aag ctt gtc 338 Lys Pro Ile Leu Ala Ala Gly Ser Asp Gly Val Gly Thr Lys Leu Val 95 100 105 atc gcc cag atg atg gac aag cac gac acc atc ggc atc gac ctt gtt 386 Ile Ala Gln Met Met Asp Lys His Asp Thr Ile Gly Ile Asp Leu Val 110 115 120 gca atg tgt gtg gat gac ctc gtt gtc acc ggc gca gag cca ctg ttc 434 Ala Met Cys Val Asp Asp Leu Val Val Thr Gly Ala Glu Pro Leu Phe 125 130 135 140 ctc cag gac tac atc gcc atc ggc aag gtt gtc cca gag cac gtt gct 482 Leu Gln Asp Tyr Ile Ala Ile Gly Lys Val Val Pro Glu His Val Ala 145 150 155 gag atc gtc tcc ggt atc gca gaa ggc tgt gtc cag gca ggc tgt gct 530 Glu Ile Val Ser Gly Ile Ala Glu Gly Cys Val Gln Ala Gly Cys Ala 160 165 170 ctg ctc ggt ggc gaa acc gca gaa cac cca ggt gtt atg gaa cca gac 578 Leu Leu Gly Gly Glu Thr Ala Glu His Pro Gly Val Met Glu Pro Asp 175 180 185 cac tac gat gtc tcc gca act gca gtc ggc gtt gtc gaa gca gat gaa 626 His Tyr Asp Val Ser Ala Thr Ala Val Gly Val Val Glu Ala Asp Glu 190 195 200 ctg cta gga cca gac cgc gtc cgc gca ggc gac gtc ctc atc ggc atg 674 Leu Leu Gly Pro Asp Arg Val Arg Ala Gly Asp Val Leu Ile Gly Met 205 210 215 220 gct tcc tcc ggt ctg cac tcc aac ggt tac tcc ctg gct cgc cac gtc 722 Ala Ser Ser Gly Leu His Ser Asn Gly Tyr Ser Leu Ala Arg His Val 225 230 235 ctc ctg gaa aag gca ggc ctg gcg ctt gac gga cac atc gaa gaa ctc 770 Leu Leu Glu Lys Ala Gly Leu Ala Leu Asp Gly His Ile Glu Glu Leu 240 245 250 gga cgc acc ccc ggt gaa gaa ctt ctc gag cca acc cgc atg tac gcc 818 Gly Arg Thr Pro Gly Glu Glu Leu Leu Glu Pro Thr Arg Met Tyr Ala 255 260 265 <210> 926 <211> 268 <212> PRT <213> Corynebacterium glutamicum <400> 926 Leu Leu Ser Pro Tyr Ala Trp Gly Leu Ser Arg Ala Leu Leu Asp Ser 1 5 10 15 Tyr Val Pro Asn Lys Phe Gln Thr Pro Ala Gly Glu Ala Lys Tyr Thr 20 25 30 Met Ser Asp His Gln Asp Thr Thr Ala Glu Gly Val Ser Tyr Ala Ala 35 40 45 Ala Gly Val Asp Ile Glu Ala Gly Asp Arg Ala Val Glu Leu Phe Ala 50 55 60 Pro Met Ala Lys Arg Ala Thr Arg Pro Glu Val Leu Gly Asn Leu Gly 65 70 75 80 Gly Phe Ala Gly Leu Phe Glu Leu Gly Lys Tyr Lys Lys Pro Ile Leu 85 90 95 Ala Ala Gly Ser Asp Gly Val Gly Thr Lys Leu Val Ile Ala Gln Met 100 105 110 Met Asp Lys His Asp Thr Ile Gly Ile Asp Leu Val Ala Met Cys Val 115 120 125 Asp Asp Leu Val Val Thr Gly Ala Glu Pro Leu Phe Leu Gln Asp Tyr 130 135 140 Ile Ala Ile Gly Lys Val Val Pro Glu His Val Ala Glu Ile Val Ser 145 150 155 160 Gly Ile Ala Glu Gly Cys Val Gln Ala Gly Cys Ala Leu Leu Gly Gly 165 170 175 Glu Thr Ala Glu His Pro Gly Val Met Glu Pro Asp His Tyr Asp Val 180 185 190 Ser Ala Thr Ala Val Gly Val Val Glu Ala Asp Glu Leu Leu Gly Pro 195 200 205 Asp Arg Val Arg Ala Gly Asp Val Leu Ile Gly Met Ala Ser Ser Gly 210 215 220 Leu His Ser Asn Gly Tyr Ser Leu Ala Arg His Val Leu Leu Glu Lys 225 230 235 240 Ala Gly Leu Ala Leu Asp Gly His Ile Glu Glu Leu Gly Arg Thr Pro 245 250 255 Gly Glu Glu Leu Leu Glu Pro Thr Arg Met Tyr Ala 260 265 <210> 927 <211> 338 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(315) <223> FRXA00770 <400> 927 gtc acc ggc ggc ggc ctc gca ggc aac ctc gag cgg gtt gtc cca gaa 48 Val Thr Gly Gly Gly Leu Ala Gly Asn Leu Glu Arg Val Val Pro Glu 1 5 10 15 ggg ctc gtc gca gaa atg tcc cga gca act tgg acc cca ggc caa atc 96 Gly Leu Val Ala Glu Met Ser Arg Ala Thr Trp Thr Pro Gly Gln Ile 20 25 30 ttc cgc acc atc tcc tct gtg ggc aag gtt tcc cgc gaa gaa atg gaa 144 Phe Arg Thr Ile Ser Ser Val Gly Lys Val Ser Arg Glu Glu Met Glu 35 40 45 aag acc ttc aac atg ggt gtc ggc atg gtt gca gtc gtt gct gaa aag 192 Lys Thr Phe Asn Met Gly Val Gly Met Val Ala Val Val Ala Glu Lys 50 55 60 gac cgc gac cgc gcc ctg gca atg ctc acc gca cgt cac att gac tgc 240 Asp Arg Asp Arg Ala Leu Ala Met Leu Thr Ala Arg His Ile Asp Cys 65 70 75 80 tgg gaa atc gga acc gta cgc aac ggt gaa gag gga gag cct cgc gtg 288 Trp Glu Ile Gly Thr Val Arg Asn Gly Glu Glu Gly Glu Pro Arg Val 85 90 95 atc ctc aac ggc gag cac cct ggc tac taagcccaac tgtctgctct 335 Ile Leu Asn Gly Glu His Pro Gly Tyr 100 105 aag 338 <210> 928 <211> 105 <212> PRT <213> Corynebacterium glutamicum <400> 928 Val Thr Gly Gly Gly Leu Ala Gly Asn Leu Glu Arg Val Val Pro Glu 1 5 10 15 Gly Leu Val Ala Glu Met Ser Arg Ala Thr Trp Thr Pro Gly Gln Ile 20 25 30 Phe Arg Thr Ile Ser Ser Val Gly Lys Val Ser Arg Glu Glu Met Glu 35 40 45 Lys Thr Phe Asn Met Gly Val Gly Met Val Ala Val Val Ala Glu Lys 50 55 60 Asp Arg Asp Arg Ala Leu Ala Met Leu Thr Ala Arg His Ile Asp Cys 65 70 75 80 Trp Glu Ile Gly Thr Val Arg Asn Gly Glu Glu Gly Glu Pro Arg Val 85 90 95 Ile Leu Asn Gly Glu His Pro Gly Tyr 100 105 <210> 929 <211> 1320 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1297) <223> RXN02345 <400> 929 accaccgacc ctatgtaatc aaccaggttc ccaaggctcg aaaagtggaa gcgctgctca 60 aagatcttac attttggtga aggcgttata gttaggactt gtg act tct aca gga 115 Val Thr Ser Thr Gly 1 5 aac caa gcc cac gct cca gga atg ccc atc gtc gca gta att ggt gac 163 Asn Gln Ala His Ala Pro Gly Met Pro Ile Val Ala Val Ile Gly Asp 10 15 20 ggc caa tta gcc cgc atg atg cag acc tcc gcc atc gaa ctc gga caa 211 Gly Gln Leu Ala Arg Met Met Gln Thr Ser Ala Ile Glu Leu Gly Gln 25 30 35 tca ctg cga gtt cta gct gga gcg ccg gat tcc tcc gca gct caa gta 259 Ser Leu Arg Val Leu Ala Gly Ala Pro Asp Ser Ser Ala Ala Gln Val 40 45 50 gct gct gat gtt gtt ctc ggc gat tac acc aac att gat gat ctg cgc 307 Ala Ala Asp Val Val Leu Gly Asp Tyr Thr Asn Ile Asp Asp Leu Arg 55 60 65 gtc gcc atc gaa ggc gcc gat gtg atg acc ttc gac cac gag cac gtc 355 Val Ala Ile Glu Gly Ala Asp Val Met Thr Phe Asp His Glu His Val 70 75 80 85 ccc aac gaa cac ctg cac caa ctc atc gca gaa ggc gtc aac gtt cag 403 Pro Asn Glu His Leu His Gln Leu Ile Ala Glu Gly Val Asn Val Gln 90 95 100 cca cgc cca gaa gcg ctg gtc aac gca caa gac aaa ctt gtc atg cgc 451 Pro Arg Pro Glu Ala Leu Val Asn Ala Gln Asp Lys Leu Val Met Arg 105 110 115 aag cgt cta cgt gaa ctc ggc gca cca gtc cca cca ttt gct gcc att 499 Lys Arg Leu Arg Glu Leu Gly Ala Pro Val Pro Pro Phe Ala Ala Ile 120 125 130 gaa tca gtc gaa gat gca gtg gga ttc ttc gaa gca gtt gat ggc caa 547 Glu Ser Val Glu Asp Ala Val Gly Phe Phe Glu Ala Val Asp Gly Gln 135 140 145 gtt tgc ctc aaa gca cgc cgt ggc gga tac gac ggc aag ggc gta tgg 595 Val Cys Leu Lys Ala Arg Arg Gly Gly Tyr Asp Gly Lys Gly Val Trp 150 155 160 165 ttc cca gcc gat gta gca gag ctt cag tcg ctt gtg gca gag ctt ctc 643 Phe Pro Ala Asp Val Ala Glu Leu Gln Ser Leu Val Ala Glu Leu Leu 170 175 180 gac ggc ggc acc cca ctc atg gca gaa aag aaa gtt gcc ctc aac agg 691 Asp Gly Gly Thr Pro Leu Met Ala Glu Lys Lys Val Ala Leu Asn Arg 185 190 195 gaa ctg tcc gcc atg gtt gcc cgc acc cca agt gga gaa acc aaa gcg 739 Glu Leu Ser Ala Met Val Ala Arg Thr Pro Ser Gly Glu Thr Lys Ala 200 205 210 tgg cca gtc gta gaa tca gtg cag aag aac ggt gtg tgt gca gaa gca 787 Trp Pro Val Val Glu Ser Val Gln Lys Asn Gly Val Cys Ala Glu Ala 215 220 225 atc gct ccc gca cct gaa cta tcc gca gaa ctg cag gaa tcc acc aga 835 Ile Ala Pro Ala Pro Glu Leu Ser Ala Glu Leu Gln Glu Ser Thr Arg 230 235 240 245 gga ttg gcc cag aag atc gcc acg gaa ctc ggc gtc act ggt gtc ttg 883 Gly Leu Ala Gln Lys Ile Ala Thr Glu Leu Gly Val Thr Gly Val Leu 250 255 260 gca gtg gag ctt ttt gaa acc ctc gac caa aac ggg cag cca gag atc 931 Ala Val Glu Leu Phe Glu Thr Leu Asp Gln Asn Gly Gln Pro Glu Ile 265 270 275 ttt gtc aac gag ctc gcc atg cgt tca cac aac acc ggc cac tgg act 979 Phe Val Asn Glu Leu Ala Met Arg Ser His Asn Thr Gly His Trp Thr 280 285 290 caa gat ggc tgc gtg acc agc caa ttc gag cag cac ctc cgc gca gtc 1027 Gln Asp Gly Cys Val Thr Ser Gln Phe Glu Gln His Leu Arg Ala Val 295 300 305 ctc gac tac cca ctg ggt gct acc gac act ttg gct gat tac acc gtg 1075 Leu Asp Tyr Pro Leu Gly Ala Thr Asp Thr Leu Ala Asp Tyr Thr Val 310 315 320 325 atg gcc aac gtg ctc ggt gcc gac acc gac cca gag atg ccc atg gca 1123 Met Ala Asn Val Leu Gly Ala Asp Thr Asp Pro Glu Met Pro Met Ala 330 335 340 acc cgc atg gtg gaa gtg ggg cgc aag tac cca gat gcc aag att cac 1171 Thr Arg Met Val Glu Val Gly Arg Lys Tyr Pro Asp Ala Lys Ile His 345 350 355 ctc tac ggc aag gga cat cgc ccg gga cga aag att ggc cac gtc aac 1219 Leu Tyr Gly Lys Gly His Arg Pro Gly Arg Lys Ile Gly His Val Asn 360 365 370 atg gtg gga tcc gac ctt gaa aag acc cga gcc gaa gcc ctg gcc tgc 1267 Met Val Gly Ser Asp Leu Glu Lys Thr Arg Ala Glu Ala Leu Ala Cys 375 380 385 gca tac ttc ctt gtc aac gct cgc tgg gat taggtctttt ctgagcgcta 1317 Ala Tyr Phe Leu Val Asn Ala Arg Trp Asp 390 395 gca 1320 <210> 930 <211> 399 <212> PRT <213> Corynebacterium glutamicum <400> 930 Val Thr Ser Thr Gly Asn Gln Ala His Ala Pro Gly Met Pro Ile Val 1 5 10 15 Ala Val Ile Gly Asp Gly Gln Leu Ala Arg Met Met Gln Thr Ser Ala 20 25 30 Ile Glu Leu Gly Gln Ser Leu Arg Val Leu Ala Gly Ala Pro Asp Ser 35 40 45 Ser Ala Ala Gln Val Ala Ala Asp Val Val Leu Gly Asp Tyr Thr Asn 50 55 60 Ile Asp Asp Leu Arg Val Ala Ile Glu Gly Ala Asp Val Met Thr Phe 65 70 75 80 Asp His Glu His Val Pro Asn Glu His Leu His Gln Leu Ile Ala Glu 85 90 95 Gly Val Asn Val Gln Pro Arg Pro Glu Ala Leu Val Asn Ala Gln Asp 100 105 110 Lys Leu Val Met Arg Lys Arg Leu Arg Glu Leu Gly Ala Pro Val Pro 115 120 125 Pro Phe Ala Ala Ile Glu Ser Val Glu Asp Ala Val Gly Phe Phe Glu 130 135 140 Ala Val Asp Gly Gln Val Cys Leu Lys Ala Arg Arg Gly Gly Tyr Asp 145 150 155 160 Gly Lys Gly Val Trp Phe Pro Ala Asp Val Ala Glu Leu Gln Ser Leu 165 170 175 Val Ala Glu Leu Leu Asp Gly Gly Thr Pro Leu Met Ala Glu Lys Lys 180 185 190 Val Ala Leu Asn Arg Glu Leu Ser Ala Met Val Ala Arg Thr Pro Ser 195 200 205 Gly Glu Thr Lys Ala Trp Pro Val Val Glu Ser Val Gln Lys Asn Gly 210 215 220 Val Cys Ala Glu Ala Ile Ala Pro Ala Pro Glu Leu Ser Ala Glu Leu 225 230 235 240 Gln Glu Ser Thr Arg Gly Leu Ala Gln Lys Ile Ala Thr Glu Leu Gly 245 250 255 Val Thr Gly Val Leu Ala Val Glu Leu Phe Glu Thr Leu Asp Gln Asn 260 265 270 Gly Gln Pro Glu Ile Phe Val Asn Glu Leu Ala Met Arg Ser His Asn 275 280 285 Thr Gly His Trp Thr Gln Asp Gly Cys Val Thr Ser Gln Phe Glu Gln 290 295 300 His Leu Arg Ala Val Leu Asp Tyr Pro Leu Gly Ala Thr Asp Thr Leu 305 310 315 320 Ala Asp Tyr Thr Val Met Ala Asn Val Leu Gly Ala Asp Thr Asp Pro 325 330 335 Glu Met Pro Met Ala Thr Arg Met Val Glu Val Gly Arg Lys Tyr Pro 340 345 350 Asp Ala Lys Ile His Leu Tyr Gly Lys Gly His Arg Pro Gly Arg Lys 355 360 365 Ile Gly His Val Asn Met Val Gly Ser Asp Leu Glu Lys Thr Arg Ala 370 375 380 Glu Ala Leu Ala Cys Ala Tyr Phe Leu Val Asn Ala Arg Trp Asp 385 390 395 <210> 931 <211> 833 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(810) <223> FRXA02345 <400> 931 ttt gct gcc att gaa tca gtc gaa gat gca gtg gga ttc ttc gaa gca 48 Phe Ala Ala Ile Glu Ser Val Glu Asp Ala Val Gly Phe Phe Glu Ala 1 5 10 15 gtt gat ggc caa gtt tgc ctc aaa gca cgc cgt ggc gga tac gac ggc 96 Val Asp Gly Gln Val Cys Leu Lys Ala Arg Arg Gly Gly Tyr Asp Gly 20 25 30 aag ggc gta tgg ttc cca gcc gat gta gca gag ctt cag tcg ctt gtg 144 Lys Gly Val Trp Phe Pro Ala Asp Val Ala Glu Leu Gln Ser Leu Val 35 40 45 gca gag ctt ctc gac ggc ggc acc cca ctc atg gca gaa aag aaa gtt 192 Ala Glu Leu Leu Asp Gly Gly Thr Pro Leu Met Ala Glu Lys Lys Val 50 55 60 gcc ctc aac agg gaa ctg tcc gcc atg gtt gcc cgc acc cca agt gga 240 Ala Leu Asn Arg Glu Leu Ser Ala Met Val Ala Arg Thr Pro Ser Gly 65 70 75 80 gaa acc aaa gcg tgg cca gtc gta gaa tca gtg cag aag aac ggt gtg 288 Glu Thr Lys Ala Trp Pro Val Val Glu Ser Val Gln Lys Asn Gly Val 85 90 95 tgt gca gaa gca atc gct ccc gca cct gaa cta tcc gca gaa ctg cag 336 Cys Ala Glu Ala Ile Ala Pro Ala Pro Glu Leu Ser Ala Glu Leu Gln 100 105 110 gaa tcc acc aga gga ttg gcc cag aag atc gcc acg gaa ctc ggc gtc 384 Glu Ser Thr Arg Gly Leu Ala Gln Lys Ile Ala Thr Glu Leu Gly Val 115 120 125 act ggt gtc ttg gca gtg gag ctt ttt gaa acc ctc gac caa aac ggg 432 Thr Gly Val Leu Ala Val Glu Leu Phe Glu Thr Leu Asp Gln Asn Gly 130 135 140 cag cca gag atc ttt gtc aac gag ctc gcc atg cgt tca cac aac acc 480 Gln Pro Glu Ile Phe Val Asn Glu Leu Ala Met Arg Ser His Asn Thr 145 150 155 160 ggc cac tgg act caa gat ggc tgc gtg acc agc caa ttc gag cag cac 528 Gly His Trp Thr Gln Asp Gly Cys Val Thr Ser Gln Phe Glu Gln His 165 170 175 ctc cgc gca gtc ctc gac tac cca ctg ggt gct acc gac act ttg gct 576 Leu Arg Ala Val Leu Asp Tyr Pro Leu Gly Ala Thr Asp Thr Leu Ala 180 185 190 gat tac acc gtg atg gcc aac gtg ctc ggt gcc gac acc gac cca gag 624 Asp Tyr Thr Val Met Ala Asn Val Leu Gly Ala Asp Thr Asp Pro Glu 195 200 205 atg ccc atg gca acc cgc atg gtg gaa gtg ggg cgc aag tac cca gat 672 Met Pro Met Ala Thr Arg Met Val Glu Val Gly Arg Lys Tyr Pro Asp 210 215 220 gcc aag att cac ctc tac ggc aag gga cat cgc ccg gga cga aag att 720 Ala Lys Ile His Leu Tyr Gly Lys Gly His Arg Pro Gly Arg Lys Ile 225 230 235 240 ggc cac gtc aac atg gtg gga tcc gac ctt gaa aag acc cga gcc gaa 768 Gly His Val Asn Met Val Gly Ser Asp Leu Glu Lys Thr Arg Ala Glu 245 250 255 gcc ctg gcc tgc gca tac ttc ctt gtc aac gct cgc tgg gat 810 Ala Leu Ala Cys Ala Tyr Phe Leu Val Asn Ala Arg Trp Asp 260 265 270 taggtctttt ctgagcgcta gca 833 <210> 932 <211> 270 <212> PRT <213> Corynebacterium glutamicum <400> 932 Phe Ala Ala Ile Glu Ser Val Glu Asp Ala Val Gly Phe Phe Glu Ala 1 5 10 15 Val Asp Gly Gln Val Cys Leu Lys Ala Arg Arg Gly Gly Tyr Asp Gly 20 25 30 Lys Gly Val Trp Phe Pro Ala Asp Val Ala Glu Leu Gln Ser Leu Val 35 40 45 Ala Glu Leu Leu Asp Gly Gly Thr Pro Leu Met Ala Glu Lys Lys Val 50 55 60 Ala Leu Asn Arg Glu Leu Ser Ala Met Val Ala Arg Thr Pro Ser Gly 65 70 75 80 Glu Thr Lys Ala Trp Pro Val Val Glu Ser Val Gln Lys Asn Gly Val 85 90 95 Cys Ala Glu Ala Ile Ala Pro Ala Pro Glu Leu Ser Ala Glu Leu Gln 100 105 110 Glu Ser Thr Arg Gly Leu Ala Gln Lys Ile Ala Thr Glu Leu Gly Val 115 120 125 Thr Gly Val Leu Ala Val Glu Leu Phe Glu Thr Leu Asp Gln Asn Gly 130 135 140 Gln Pro Glu Ile Phe Val Asn Glu Leu Ala Met Arg Ser His Asn Thr 145 150 155 160 Gly His Trp Thr Gln Asp Gly Cys Val Thr Ser Gln Phe Glu Gln His 165 170 175 Leu Arg Ala Val Leu Asp Tyr Pro Leu Gly Ala Thr Asp Thr Leu Ala 180 185 190 Asp Tyr Thr Val Met Ala Asn Val Leu Gly Ala Asp Thr Asp Pro Glu 195 200 205 Met Pro Met Ala Thr Arg Met Val Glu Val Gly Arg Lys Tyr Pro Asp 210 215 220 Ala Lys Ile His Leu Tyr Gly Lys Gly His Arg Pro Gly Arg Lys Ile 225 230 235 240 Gly His Val Asn Met Val Gly Ser Asp Leu Glu Lys Thr Arg Ala Glu 245 250 255 Ala Leu Ala Cys Ala Tyr Phe Leu Val Asn Ala Arg Trp Asp 260 265 270 <210> 933 <211> 618 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(595) <223> RXN02350 <400> 933 aagcatttct ccaacacttt tgatggacag attaacgctt aaaaggcctg ttatagactg 60 ataaaccgat acgtactttt cgcgcttaag gagaatttca gtg ggt cct cta gtt 115 Val Gly Pro Leu Val 1 5 ggt ttg atc atg ggt tcg gat tcg gat tgg gac act gta gcg cca gct 163 Gly Leu Ile Met Gly Ser Asp Ser Asp Trp Asp Thr Val Ala Pro Ala 10 15 20 gca gag gta ctc gct gag ttt ggc att cct ttt gaa gtc gga gtt gtc 211 Ala Glu Val Leu Ala Glu Phe Gly Ile Pro Phe Glu Val Gly Val Val 25 30 35 tct gca cac cgc acc cca gag aag atg ctc aac tac gca aag act gca 259 Ser Ala His Arg Thr Pro Glu Lys Met Leu Asn Tyr Ala Lys Thr Ala 40 45 50 cat gag cgc ggc atc aag acg atc atc gcg tgt gct ggc ggc gct gca 307 His Glu Arg Gly Ile Lys Thr Ile Ile Ala Cys Ala Gly Gly Ala Ala 55 60 65 cac ctg cca ggc atg gtg gct gca gca act cca ctt cca gtc atc ggt 355 His Leu Pro Gly Met Val Ala Ala Ala Thr Pro Leu Pro Val Ile Gly 70 75 80 85 gtt cca cgc gca ttg aag gat ctc gac ggt ttg gat tcc ttg ctg tcc 403 Val Pro Arg Ala Leu Lys Asp Leu Asp Gly Leu Asp Ser Leu Leu Ser 90 95 100 atc gtc cag atg cca ggc ggc gtt cca gtc gcc act gtc tcc atc ggt 451 Ile Val Gln Met Pro Gly Gly Val Pro Val Ala Thr Val Ser Ile Gly 105 110 115 ggc gcg aag aat gca ggc cta ctt gcc gtt cgt att ctc ggt gct ggt 499 Gly Ala Lys Asn Ala Gly Leu Leu Ala Val Arg Ile Leu Gly Ala Gly 120 125 130 gat cct tct ttg gtc acg aag atg gcc gat tac caa gag aat atg gcg 547 Asp Pro Ser Leu Val Thr Lys Met Ala Asp Tyr Gln Glu Asn Met Ala 135 140 145 aag gaa gtt gaa gcc aag gac gaa gca ctg aag aag cgc ttg ctc ggc 595 Lys Glu Val Glu Ala Lys Asp Glu Ala Leu Lys Lys Arg Leu Leu Gly 150 155 160 165 taatgaatcc gatcgtggtg ctg 618 <210> 934 <211> 165 <212> PRT <213> Corynebacterium glutamicum <400> 934 Val Gly Pro Leu Val Gly Leu Ile Met Gly Ser Asp Ser Asp Trp Asp 1 5 10 15 Thr Val Ala Pro Ala Ala Glu Val Leu Ala Glu Phe Gly Ile Pro Phe 20 25 30 Glu Val Gly Val Val Ser Ala His Arg Thr Pro Glu Lys Met Leu Asn 35 40 45 Tyr Ala Lys Thr Ala His Glu Arg Gly Ile Lys Thr Ile Ile Ala Cys 50 55 60 Ala Gly Gly Ala Ala His Leu Pro Gly Met Val Ala Ala Ala Thr Pro 65 70 75 80 Leu Pro Val Ile Gly Val Pro Arg Ala Leu Lys Asp Leu Asp Gly Leu 85 90 95 Asp Ser Leu Leu Ser Ile Val Gln Met Pro Gly Gly Val Pro Val Ala 100 105 110 Thr Val Ser Ile Gly Gly Ala Lys Asn Ala Gly Leu Leu Ala Val Arg 115 120 125 Ile Leu Gly Ala Gly Asp Pro Ser Leu Val Thr Lys Met Ala Asp Tyr 130 135 140 Gln Glu Asn Met Ala Lys Glu Val Glu Ala Lys Asp Glu Ala Leu Lys 145 150 155 160 Lys Arg Leu Leu Gly 165 <210> 935 <211> 223 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(223) <223> FRXA02346 <400> 935 aagcatttct ccaacacttt tgatggacag attaacgctt aaaaggcctg ttatagactg 60 ataaaccgat acgtaacttt cgcgcttaag gagaatttca gtg ggt cct cta gtt 115 Val Gly Pro Leu Val 1 5 ggt ttg atc atg ggt tcg gat tcg gat tgg gac act gta gcg cca gct 163 Gly Leu Ile Met Gly Ser Asp Ser Asp Trp Asp Thr Val Ala Pro Ala 10 15 20 gca gag gta ctc gct gag ttt ggc att cct ttt gaa gtc gga gtt gtc 211 Ala Glu Val Leu Ala Glu Phe Gly Ile Pro Phe Glu Val Gly Val Val 25 30 35 tct gca cac cgc 223 Ser Ala His Arg 40 <210> 936 <211> 41 <212> PRT <213> Corynebacterium glutamicum <400> 936 Val Gly Pro Leu Val Gly Leu Ile Met Gly Ser Asp Ser Asp Trp Asp 1 5 10 15 Thr Val Ala Pro Ala Ala Glu Val Leu Ala Glu Phe Gly Ile Pro Phe 20 25 30 Glu Val Gly Val Val Ser Ala His Arg 35 40 <210> 937 <211> 252 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (20)..(229) <223> FRXA02350 <400> 937 atactaggat ctcgacggt ttg gat tcc ttg ctg tcc atc gtc cag atg cca 52 Leu Asp Ser Leu Leu Ser Ile Val Gln Met Pro 1 5 10 ggc ggc gtt cca gtc gcc act gtc tcc atc ggt ggc gcg aag aat gca 100 Gly Gly Val Pro Val Ala Thr Val Ser Ile Gly Gly Ala Lys Asn Ala 15 20 25 ggc cta ctt gcc gtt cgt att ctc ggt gct ggt gat cct tct ttg gtc 148 Gly Leu Leu Ala Val Arg Ile Leu Gly Ala Gly Asp Pro Ser Leu Val 30 35 40 acg aag atg gcc gat tac caa gag aat atg gcg aag gaa gtt gaa gcc 196 Thr Lys Met Ala Asp Tyr Gln Glu Asn Met Ala Lys Glu Val Glu Ala 45 50 55 aag gac gaa gca ctg aag aag cgc ttg ctc ggc taatgaatcc gatcgtggtg 249 Lys Asp Glu Ala Leu Lys Lys Arg Leu Leu Gly 60 65 70 ctg 252 <210> 938 <211> 70 <212> PRT <213> Corynebacterium glutamicum <400> 938 Leu Asp Ser Leu Leu Ser Ile Val Gln Met Pro Gly Gly Val Pro Val 1 5 10 15 Ala Thr Val Ser Ile Gly Gly Ala Lys Asn Ala Gly Leu Leu Ala Val 20 25 30 Arg Ile Leu Gly Ala Gly Asp Pro Ser Leu Val Thr Lys Met Ala Asp 35 40 45 Tyr Gln Glu Asn Met Ala Lys Glu Val Glu Ala Lys Asp Glu Ala Leu 50 55 60 Lys Lys Arg Leu Leu Gly 65 70 <210> 939 <211> 999 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(976) <223> RXA01087 <400> 939 ggccttggca gagaactcgg ccccgaaggt cttgcttcct accaagaaac ccaaaccatt 60 tatctctaat ccaaactgca cctatatata aggagtaaaa atg caa acc ctt gct 115 Met Gln Thr Leu Ala 1 5 gct att gtt cgt gcc acg aag caa cct ttt gag atc acc acc att gat 163 Ala Ile Val Arg Ala Thr Lys Gln Pro Phe Glu Ile Thr Thr Ile Asp 10 15 20 ctg gat gca cca cga cca gat gaa gtt caa atc cgt gtt att gct gcc 211 Leu Asp Ala Pro Arg Pro Asp Glu Val Gln Ile Arg Val Ile Ala Ala 25 30 35 gga gtg cgc cac act gac gca att gtt cgt gat cag att tac cca act 259 Gly Val Arg His Thr Asp Ala Ile Val Arg Asp Gln Ile Tyr Pro Thr 40 45 50 ttt ctt ccc gca gtt ttc ggc cac gaa ggc gcc gga gta gtt gtc gcc 307 Phe Leu Pro Ala Val Phe Gly His Glu Gly Ala Gly Val Val Val Ala 55 60 65 gtg ggt tct gca gtc acc tcg gtg aaa cca gat gac aag gta gtg ctg 355 Val Gly Ser Ala Val Thr Ser Val Lys Pro Asp Asp Lys Val Val Leu 70 75 80 85 gga ttc aac tct tgt ggc cag tgc ttg aag tgt ttg ggc ggt aag cct 403 Gly Phe Asn Ser Cys Gly Gln Cys Leu Lys Cys Leu Gly Gly Lys Pro 90 95 100 gcg tac tgt gag aaa ttc tat gac cgc aac ttc gca tgc acc cgc gat 451 Ala Tyr Cys Glu Lys Phe Tyr Asp Arg Asn Phe Ala Cys Thr Arg Asp 105 110 115 gcc ggg cac act act ttg ttt acc cgt gca aca aaa gag cag gca gag 499 Ala Gly His Thr Thr Leu Phe Thr Arg Ala Thr Lys Glu Gln Ala Glu 120 125 130 gcc atc atc gac acc ctt gat gat gtt ttc tac gat gcg gat gcg ggt 547 Ala Ile Ile Asp Thr Leu Asp Asp Val Phe Tyr Asp Ala Asp Ala Gly 135 140 145 ttc ctg gca tac cca gca act ccc cca gag gct tcg gga gta agc gtg 595 Phe Leu Ala Tyr Pro Ala Thr Pro Pro Glu Ala Ser Gly Val Ser Val 150 155 160 165 ttg gtt gtc gcg gct ggt acc tct gat ctc ccc caa gca aag gaa gca 643 Leu Val Val Ala Ala Gly Thr Ser Asp Leu Pro Gln Ala Lys Glu Ala 170 175 180 cta cac act gcc tcc tac ttg ggg cgc tcc acc tca ctg att gtt gat 691 Leu His Thr Ala Ser Tyr Leu Gly Arg Ser Thr Ser Leu Ile Val Asp 185 190 195 ttt gga gtg gct ggc atc cac cgc ctg ctt tca tac gaa gaa gaa ctc 739 Phe Gly Val Ala Gly Ile His Arg Leu Leu Ser Tyr Glu Glu Glu Leu 200 205 210 cgc gct gcg ggc gtg ctc atc gtt gcc gct gga atg gat ggt gcg cta 787 Arg Ala Ala Gly Val Leu Ile Val Ala Ala Gly Met Asp Gly Ala Leu 215 220 225 ccc gga gtt gtc gca ggc tta gtg tcc gca cct gtc gtc gca ctg cca 835 Pro Gly Val Val Ala Gly Leu Val Ser Ala Pro Val Val Ala Leu Pro 230 235 240 245 acc tcc gtg gga tac ggc gca ggt gct gga gga atc gca cca ctt ctg 883 Thr Ser Val Gly Tyr Gly Ala Gly Ala Gly Gly Ile Ala Pro Leu Leu 250 255 260 acc atg ctt aac gcc tgc gcg ccg gga gtt gga gtg gtc aac att gat 931 Thr Met Leu Asn Ala Cys Ala Pro Gly Val Gly Val Val Asn Ile Asp 265 270 275 aac ggc tat gga gca gga cac ctg gct gcg cag att gcg gcg agg 976 Asn Gly Tyr Gly Ala Gly His Leu Ala Ala Gln Ile Ala Ala Arg 280 285 290 taagggtttc gcaggagacg aac 999 <210> 940 <211> 292 <212> PRT <213> Corynebacterium glutamicum <400> 940 Met Gln Thr Leu Ala Ala Ile Val Arg Ala Thr Lys Gln Pro Phe Glu 1 5 10 15 Ile Thr Thr Ile Asp Leu Asp Ala Pro Arg Pro Asp Glu Val Gln Ile 20 25 30 Arg Val Ile Ala Ala Gly Val Arg His Thr Asp Ala Ile Val Arg Asp 35 40 45 Gln Ile Tyr Pro Thr Phe Leu Pro Ala Val Phe Gly His Glu Gly Ala 50 55 60 Gly Val Val Val Ala Val Gly Ser Ala Val Thr Ser Val Lys Pro Asp 65 70 75 80 Asp Lys Val Val Leu Gly Phe Asn Ser Cys Gly Gln Cys Leu Lys Cys 85 90 95 Leu Gly Gly Lys Pro Ala Tyr Cys Glu Lys Phe Tyr Asp Arg Asn Phe 100 105 110 Ala Cys Thr Arg Asp Ala Gly His Thr Thr Leu Phe Thr Arg Ala Thr 115 120 125 Lys Glu Gln Ala Glu Ala Ile Ile Asp Thr Leu Asp Asp Val Phe Tyr 130 135 140 Asp Ala Asp Ala Gly Phe Leu Ala Tyr Pro Ala Thr Pro Pro Glu Ala 145 150 155 160 Ser Gly Val Ser Val Leu Val Val Ala Ala Gly Thr Ser Asp Leu Pro 165 170 175 Gln Ala Lys Glu Ala Leu His Thr Ala Ser Tyr Leu Gly Arg Ser Thr 180 185 190 Ser Leu Ile Val Asp Phe Gly Val Ala Gly Ile His Arg Leu Leu Ser 195 200 205 Tyr Glu Glu Glu Leu Arg Ala Ala Gly Val Leu Ile Val Ala Ala Gly 210 215 220 Met Asp Gly Ala Leu Pro Gly Val Val Ala Gly Leu Val Ser Ala Pro 225 230 235 240 Val Val Ala Leu Pro Thr Ser Val Gly Tyr Gly Ala Gly Ala Gly Gly 245 250 255 Ile Ala Pro Leu Leu Thr Met Leu Asn Ala Cys Ala Pro Gly Val Gly 260 265 270 Val Val Asn Ile Asp Asn Gly Tyr Gly Ala Gly His Leu Ala Ala Gln 275 280 285 Ile Ala Ala Arg 290 <210> 941 <211> 1551 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1528) <223> RXA00619 <400> 941 tcaaaggaag acaccattga aggtgtgcgc aaaatcggag aattcatcaa aaaatagcag 60 cgactaggtt agtttcggtt cgtggggaat aataatttgc gtg gct gat aaa aag 115 Val Ala Asp Lys Lys 1 5 aag atc gca aac gtc ctg tcg aac cgt tac gcc tcc gcg gaa ctt tct 163 Lys Ile Ala Asn Val Leu Ser Asn Arg Tyr Ala Ser Ala Glu Leu Ser 10 15 20 aac ctg tgg agt gcc gaa gag aag atc atc atg gag cgc cag ctc tgg 211 Asn Leu Trp Ser Ala Glu Glu Lys Ile Ile Met Glu Arg Gln Leu Trp 25 30 35 atc gcc gtg atg aaa gcc cag aaa gat ttg gga gtt gag atc cct gcc 259 Ile Ala Val Met Lys Ala Gln Lys Asp Leu Gly Val Glu Ile Pro Ala 40 45 50 gag gca att gaa tcc tat gaa gca gtg atc gac cag gtt gat ttg gca 307 Glu Ala Ile Glu Ser Tyr Glu Ala Val Ile Asp Gln Val Asp Leu Ala 55 60 65 agc atc gcc gat cgt gag cgc gtc acc cgc cac gat gtg aag gcc cgc 355 Ser Ile Ala Asp Arg Glu Arg Val Thr Arg His Asp Val Lys Ala Arg 70 75 80 85 atc gaa gaa ttc aat gca ctg gct ggc cat gag cac atc cac aag ggc 403 Ile Glu Glu Phe Asn Ala Leu Ala Gly His Glu His Ile His Lys Gly 90 95 100 atg acc tcc cgc gac ctc acc gaa aat gtt gaa cag ctg cag atc cac 451 Met Thr Ser Arg Asp Leu Thr Glu Asn Val Glu Gln Leu Gln Ile His 105 110 115 cgc tcc ctt gag ctg gtc cgc aac aag ggc att gca gtt gtt gca gct 499 Arg Ser Leu Glu Leu Val Arg Asn Lys Gly Ile Ala Val Val Ala Ala 120 125 130 atc gga tcc cgc gca gcg cag tac caa agc ctg gtc atg gct ggc cgt 547 Ile Gly Ser Arg Ala Ala Gln Tyr Gln Ser Leu Val Met Ala Gly Arg 135 140 145 tcc cac aac gtg gca gcg cag gca act acc ttg ggc aag cgt ttc gca 595 Ser His Asn Val Ala Ala Gln Ala Thr Thr Leu Gly Lys Arg Phe Ala 150 155 160 165 acc gca gct gat gaa atg ctc gtg gca ctt gag cgc gtc acc gaa ctg 643 Thr Ala Ala Asp Glu Met Leu Val Ala Leu Glu Arg Val Thr Glu Leu 170 175 180 ctc aac cgc tac cca ctt cgc gga atc aag ggc cca atg gga acc gcc 691 Leu Asn Arg Tyr Pro Leu Arg Gly Ile Lys Gly Pro Met Gly Thr Ala 185 190 195 caa gac atg ctt gac ctc atg gaa ggc gac gag gct cgt ctc tcc gat 739 Gln Asp Met Leu Asp Leu Met Glu Gly Asp Glu Ala Arg Leu Ser Asp 200 205 210 ctg gaa acc cgc atc gca gca cac ctc ggc ttt gat cgc gtc ttc gac 787 Leu Glu Thr Arg Ile Ala Ala His Leu Gly Phe Asp Arg Val Phe Asp 215 220 225 tcc gtc ggc cag gtc tac cca cgt tcc ctt gac ttc gat gca gta tct 835 Ser Val Gly Gln Val Tyr Pro Arg Ser Leu Asp Phe Asp Ala Val Ser 230 235 240 245 gct ctg gtt cag ctt ggc tcc ggc cca tca tcg ctg tcc cac acc att 883 Ala Leu Val Gln Leu Gly Ser Gly Pro Ser Ser Leu Ser His Thr Ile 250 255 260 cgt ctc atg gcc ggc acc gaa act gtt acc gaa ggt ttt aag gaa ggc 931 Arg Leu Met Ala Gly Thr Glu Thr Val Thr Glu Gly Phe Lys Glu Gly 265 270 275 cag gtc ggt tcc tct gca atg cct cac aag atg aac gct cgc tcc tgt 979 Gln Val Gly Ser Ser Ala Met Pro His Lys Met Asn Ala Arg Ser Cys 280 285 290 gag cgc gtg ggc ggc ctg cag gtt att ctt cgc gga tac ctc acc atg 1027 Glu Arg Val Gly Gly Leu Gln Val Ile Leu Arg Gly Tyr Leu Thr Met 295 300 305 gtt gct gat ctt tcc ggc cag cag tgg aac gaa ggc gat gtc ttc tgc 1075 Val Ala Asp Leu Ser Gly Gln Gln Trp Asn Glu Gly Asp Val Phe Cys 310 315 320 325 tcc gtg atc cgc cgc gtt gca ctg cca gac gca ttc ttc gcg att gac 1123 Ser Val Ile Arg Arg Val Ala Leu Pro Asp Ala Phe Phe Ala Ile Asp 330 335 340 gga atg ttt gaa act ttc ctg aca gtc ctg gat gaa ttc ggt gca ttc 1171 Gly Met Phe Glu Thr Phe Leu Thr Val Leu Asp Glu Phe Gly Ala Phe 345 350 355 cct gcc atg atc gag cgc gaa ctt gag cgt tac ctg cca ttc ctg gca 1219 Pro Ala Met Ile Glu Arg Glu Leu Glu Arg Tyr Leu Pro Phe Leu Ala 360 365 370 act acc cgt atc ctc atg gcc gct gtc cgc gca ggc gtt ggc cgc gaa 1267 Thr Thr Arg Ile Leu Met Ala Ala Val Arg Ala Gly Val Gly Arg Glu 375 380 385 acc gca cac gaa gta atc aag gaa aac gct gtc gcg gtt gcc ctc aac 1315 Thr Ala His Glu Val Ile Lys Glu Asn Ala Val Ala Val Ala Leu Asn 390 395 400 405 atg cgc gaa aat ggc ggt gac cag gac ctt atc cag cgc ctc gct gct 1363 Met Arg Glu Asn Gly Gly Asp Gln Asp Leu Ile Gln Arg Leu Ala Ala 410 415 420 gat gag cgc ctc cca atg agc gaa gct gac ctt gag gca gcg ctg gct 1411 Asp Glu Arg Leu Pro Met Ser Glu Ala Asp Leu Glu Ala Ala Leu Ala 425 430 435 gac cgc cac gcc ttc atc ggt gcc gct gag tcc cag gtc tcc cgt gtg 1459 Asp Arg His Ala Phe Ile Gly Ala Ala Glu Ser Gln Val Ser Arg Val 440 445 450 ctc gac cgc att cag gtg ctt gtc gac gcc cac ccc ggc gcc gca gac 1507 Leu Asp Arg Ile Gln Val Leu Val Asp Ala His Pro Gly Ala Ala Asp 455 460 465 tac cga cca ggt gag att ctt taaaggtttt taacggcgtt cac 1551 Tyr Arg Pro Gly Glu Ile Leu 470 475 <210> 942 <211> 476 <212> PRT <213> Corynebacterium glutamicum <400> 942 Val Ala Asp Lys Lys Lys Ile Ala Asn Val Leu Ser Asn Arg Tyr Ala 1 5 10 15 Ser Ala Glu Leu Ser Asn Leu Trp Ser Ala Glu Glu Lys Ile Ile Met 20 25 30 Glu Arg Gln Leu Trp Ile Ala Val Met Lys Ala Gln Lys Asp Leu Gly 35 40 45 Val Glu Ile Pro Ala Glu Ala Ile Glu Ser Tyr Glu Ala Val Ile Asp 50 55 60 Gln Val Asp Leu Ala Ser Ile Ala Asp Arg Glu Arg Val Thr Arg His 65 70 75 80 Asp Val Lys Ala Arg Ile Glu Glu Phe Asn Ala Leu Ala Gly His Glu 85 90 95 His Ile His Lys Gly Met Thr Ser Arg Asp Leu Thr Glu Asn Val Glu 100 105 110 Gln Leu Gln Ile His Arg Ser Leu Glu Leu Val Arg Asn Lys Gly Ile 115 120 125 Ala Val Val Ala Ala Ile Gly Ser Arg Ala Ala Gln Tyr Gln Ser Leu 130 135 140 Val Met Ala Gly Arg Ser His Asn Val Ala Ala Gln Ala Thr Thr Leu 145 150 155 160 Gly Lys Arg Phe Ala Thr Ala Ala Asp Glu Met Leu Val Ala Leu Glu 165 170 175 Arg Val Thr Glu Leu Leu Asn Arg Tyr Pro Leu Arg Gly Ile Lys Gly 180 185 190 Pro Met Gly Thr Ala Gln Asp Met Leu Asp Leu Met Glu Gly Asp Glu 195 200 205 Ala Arg Leu Ser Asp Leu Glu Thr Arg Ile Ala Ala His Leu Gly Phe 210 215 220 Asp Arg Val Phe Asp Ser Val Gly Gln Val Tyr Pro Arg Ser Leu Asp 225 230 235 240 Phe Asp Ala Val Ser Ala Leu Val Gln Leu Gly Ser Gly Pro Ser Ser 245 250 255 Leu Ser His Thr Ile Arg Leu Met Ala Gly Thr Glu Thr Val Thr Glu 260 265 270 Gly Phe Lys Glu Gly Gln Val Gly Ser Ser Ala Met Pro His Lys Met 275 280 285 Asn Ala Arg Ser Cys Glu Arg Val Gly Gly Leu Gln Val Ile Leu Arg 290 295 300 Gly Tyr Leu Thr Met Val Ala Asp Leu Ser Gly Gln Gln Trp Asn Glu 305 310 315 320 Gly Asp Val Phe Cys Ser Val Ile Arg Arg Val Ala Leu Pro Asp Ala 325 330 335 Phe Phe Ala Ile Asp Gly Met Phe Glu Thr Phe Leu Thr Val Leu Asp 340 345 350 Glu Phe Gly Ala Phe Pro Ala Met Ile Glu Arg Glu Leu Glu Arg Tyr 355 360 365 Leu Pro Phe Leu Ala Thr Thr Arg Ile Leu Met Ala Ala Val Arg Ala 370 375 380 Gly Val Gly Arg Glu Thr Ala His Glu Val Ile Lys Glu Asn Ala Val 385 390 395 400 Ala Val Ala Leu Asn Met Arg Glu Asn Gly Gly Asp Gln Asp Leu Ile 405 410 415 Gln Arg Leu Ala Ala Asp Glu Arg Leu Pro Met Ser Glu Ala Asp Leu 420 425 430 Glu Ala Ala Leu Ala Asp Arg His Ala Phe Ile Gly Ala Ala Glu Ser 435 440 445 Gln Val Ser Arg Val Leu Asp Arg Ile Gln Val Leu Val Asp Ala His 450 455 460 Pro Gly Ala Ala Asp Tyr Arg Pro Gly Glu Ile Leu 465 470 475 <210> 943 <211> 1683 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1660) <223> RXA02622 <400> 943 atcaagcagg ttgagcgtaa actcattgta gaagtcctga acagcgtgga attttcgcgt 60 cagggtggcg tacaactcaa ctggagaggc taaatccttc atg agc gat gat cgt 115 Met Ser Asp Asp Arg 1 5 aag gca att aaa cgc gca cta att agc gtg tat gac aag act ggc ctg 163 Lys Ala Ile Lys Arg Ala Leu Ile Ser Val Tyr Asp Lys Thr Gly Leu 10 15 20 gag gat cta gcc cag gca ctt cac cgc gag aac gtg gaa att gtt tcc 211 Glu Asp Leu Ala Gln Ala Leu His Arg Glu Asn Val Glu Ile Val Ser 25 30 35 acc gga tcc act gcg gcg aag att gct gag ctt ggt att cct gtt acc 259 Thr Gly Ser Thr Ala Ala Lys Ile Ala Glu Leu Gly Ile Pro Val Thr 40 45 50 ccg gtt gag gag ctc acc ggt ttc cct gag tgc ctt gag ggc cgt gtg 307 Pro Val Glu Glu Leu Thr Gly Phe Pro Glu Cys Leu Glu Gly Arg Val 55 60 65 aag aca ctg cac cct aag gtt cac gct ggc atc ttg gcg gac acc cgc 355 Lys Thr Leu His Pro Lys Val His Ala Gly Ile Leu Ala Asp Thr Arg 70 75 80 85 aag gaa gac cac ctg cgt cag ctc aag gaa ctt gag gtc gcc cca ttc 403 Lys Glu Asp His Leu Arg Gln Leu Lys Glu Leu Glu Val Ala Pro Phe 90 95 100 cag ctt gtc gtg gtg aac ctg tac cca ttt gct gag acc gtt gcg tcc 451 Gln Leu Val Val Val Asn Leu Tyr Pro Phe Ala Glu Thr Val Ala Ser 105 110 115 ggc gcc gat ttc gat gct tgc gtt gag cag atc gac atc gga ggc cca 499 Gly Ala Asp Phe Asp Ala Cys Val Glu Gln Ile Asp Ile Gly Gly Pro 120 125 130 tcc atg gtt cgt gct gcg gca aag aac cac cca tct gtc gct gtg gtt 547 Ser Met Val Arg Ala Ala Ala Lys Asn His Pro Ser Val Ala Val Val 135 140 145 gtt tca ccg aac cgc tac gag gat gtc cag gaa gct ttg aag acc ggt 595 Val Ser Pro Asn Arg Tyr Glu Asp Val Gln Glu Ala Leu Lys Thr Gly 150 155 160 165 gga ttc tcc cgc gcg gag cgc acc aag ttg gct gct gag gct ttc cgc 643 Gly Phe Ser Arg Ala Glu Arg Thr Lys Leu Ala Ala Glu Ala Phe Arg 170 175 180 cac acc gca acc tac gat gtc acc gtt gca acc tgg atg agc gag cag 691 His Thr Ala Thr Tyr Asp Val Thr Val Ala Thr Trp Met Ser Glu Gln 185 190 195 ctg gct gcc gaa gat tct gag act gag ttc cca ggt tgg atc ggc acc 739 Leu Ala Ala Glu Asp Ser Glu Thr Glu Phe Pro Gly Trp Ile Gly Thr 200 205 210 acc aac acc ttg tcc cgc agc ttg cgt tac ggt gag aac cct cac cag 787 Thr Asn Thr Leu Ser Arg Ser Leu Arg Tyr Gly Glu Asn Pro His Gln 215 220 225 tct gca gct ttg tac gtg ggc aac acc cgc gga ctt gca cag gct aag 835 Ser Ala Ala Leu Tyr Val Gly Asn Thr Arg Gly Leu Ala Gln Ala Lys 230 235 240 245 cag ttc cac ggc aag gaa atg agc tac aac aac tac acc gat tct gat 883 Gln Phe His Gly Lys Glu Met Ser Tyr Asn Asn Tyr Thr Asp Ser Asp 250 255 260 gct gca tgg cgt gca gcg tgg gat cac gag cgt cct tgt gta gct atc 931 Ala Ala Trp Arg Ala Ala Trp Asp His Glu Arg Pro Cys Val Ala Ile 265 270 275 atc aag cat gca aac cct tgt ggc att gct gtt tct gat gag tcc atc 979 Ile Lys His Ala Asn Pro Cys Gly Ile Ala Val Ser Asp Glu Ser Ile 280 285 290 gca gcg gca cac cgc gag gca cac gca tgt gac tct gtg tcc gca ttc 1027 Ala Ala Ala His Arg Glu Ala His Ala Cys Asp Ser Val Ser Ala Phe 295 300 305 ggt ggc gtc atc gcg tcc aac cgt gaa gtc agc gtt gag atg gct aac 1075 Gly Gly Val Ile Ala Ser Asn Arg Glu Val Ser Val Glu Met Ala Asn 310 315 320 325 cag gtt gca gag atc ttc act gag gtc atc atc gct cct tcc tat gaa 1123 Gln Val Ala Glu Ile Phe Thr Glu Val Ile Ile Ala Pro Ser Tyr Glu 330 335 340 gag ggc gct gtg gag atc ctg agc cag aag aag aac atc cgt att ctt 1171 Glu Gly Ala Val Glu Ile Leu Ser Gln Lys Lys Asn Ile Arg Ile Leu 345 350 355 cag gct gaa gca cct gtg cgt aag ggc ttt gag tcc cgt gag atc tcc 1219 Gln Ala Glu Ala Pro Val Arg Lys Gly Phe Glu Ser Arg Glu Ile Ser 360 365 370 ggc ggt ctg ctt gtt cag gaa cgc gac ttg atc cac gct gag ggc gac 1267 Gly Gly Leu Leu Val Gln Glu Arg Asp Leu Ile His Ala Glu Gly Asp 375 380 385 aac tcc gca aac tgg act ctt gct gcc ggc tct gct gtt tct cct gag 1315 Asn Ser Ala Asn Trp Thr Leu Ala Ala Gly Ser Ala Val Ser Pro Glu 390 395 400 405 gtt ctg aag gac ctg gag ttc gcg tgg act gca gtt cgt tcc gtg aag 1363 Val Leu Lys Asp Leu Glu Phe Ala Trp Thr Ala Val Arg Ser Val Lys 410 415 420 tcc aac gca att ctg ttg gct aag aac ggc gct acc gtt ggc gtt ggc 1411 Ser Asn Ala Ile Leu Leu Ala Lys Asn Gly Ala Thr Val Gly Val Gly 425 430 435 atg gga cag gtc aac cgc gtt gac tct gct cgc ttg gct gtc gac cgt 1459 Met Gly Gln Val Asn Arg Val Asp Ser Ala Arg Leu Ala Val Asp Arg 440 445 450 gca ggt gca gag cgc gct acc ggt tcc gtt gct gct tcc gat gcg ttc 1507 Ala Gly Ala Glu Arg Ala Thr Gly Ser Val Ala Ala Ser Asp Ala Phe 455 460 465 ttc cca ttc gct gat ggc ttt gag gtt ctc gct gag gct ggc atc act 1555 Phe Pro Phe Ala Asp Gly Phe Glu Val Leu Ala Glu Ala Gly Ile Thr 470 475 480 485 gct gtt gtg cag cct ggt gga tcc att cgc gac aac gag gtc att gag 1603 Ala Val Val Gln Pro Gly Gly Ser Ile Arg Asp Asn Glu Val Ile Glu 490 495 500 gca gcc aac aag gct ggc gtg acc atg tac ctg act ggt gcg cga cac 1651 Ala Ala Asn Lys Ala Gly Val Thr Met Tyr Leu Thr Gly Ala Arg His 505 510 515 ttc gct cac taaagttttt aaagatttcg ctt 1683 Phe Ala His 520 <210> 944 <211> 520 <212> PRT <213> Corynebacterium glutamicum <400> 944 Met Ser Asp Asp Arg Lys Ala Ile Lys Arg Ala Leu Ile Ser Val Tyr 1 5 10 15 Asp Lys Thr Gly Leu Glu Asp Leu Ala Gln Ala Leu His Arg Glu Asn 20 25 30 Val Glu Ile Val Ser Thr Gly Ser Thr Ala Ala Lys Ile Ala Glu Leu 35 40 45 Gly Ile Pro Val Thr Pro Val Glu Glu Leu Thr Gly Phe Pro Glu Cys 50 55 60 Leu Glu Gly Arg Val Lys Thr Leu His Pro Lys Val His Ala Gly Ile 65 70 75 80 Leu Ala Asp Thr Arg Lys Glu Asp His Leu Arg Gln Leu Lys Glu Leu 85 90 95 Glu Val Ala Pro Phe Gln Leu Val Val Val Asn Leu Tyr Pro Phe Ala 100 105 110 Glu Thr Val Ala Ser Gly Ala Asp Phe Asp Ala Cys Val Glu Gln Ile 115 120 125 Asp Ile Gly Gly Pro Ser Met Val Arg Ala Ala Ala Lys Asn His Pro 130 135 140 Ser Val Ala Val Val Val Ser Pro Asn Arg Tyr Glu Asp Val Gln Glu 145 150 155 160 Ala Leu Lys Thr Gly Gly Phe Ser Arg Ala Glu Arg Thr Lys Leu Ala 165 170 175 Ala Glu Ala Phe Arg His Thr Ala Thr Tyr Asp Val Thr Val Ala Thr 180 185 190 Trp Met Ser Glu Gln Leu Ala Ala Glu Asp Ser Glu Thr Glu Phe Pro 195 200 205 Gly Trp Ile Gly Thr Thr Asn Thr Leu Ser Arg Ser Leu Arg Tyr Gly 210 215 220 Glu Asn Pro His Gln Ser Ala Ala Leu Tyr Val Gly Asn Thr Arg Gly 225 230 235 240 Leu Ala Gln Ala Lys Gln Phe His Gly Lys Glu Met Ser Tyr Asn Asn 245 250 255 Tyr Thr Asp Ser Asp Ala Ala Trp Arg Ala Ala Trp Asp His Glu Arg 260 265 270 Pro Cys Val Ala Ile Ile Lys His Ala Asn Pro Cys Gly Ile Ala Val 275 280 285 Ser Asp Glu Ser Ile Ala Ala Ala His Arg Glu Ala His Ala Cys Asp 290 295 300 Ser Val Ser Ala Phe Gly Gly Val Ile Ala Ser Asn Arg Glu Val Ser 305 310 315 320 Val Glu Met Ala Asn Gln Val Ala Glu Ile Phe Thr Glu Val Ile Ile 325 330 335 Ala Pro Ser Tyr Glu Glu Gly Ala Val Glu Ile Leu Ser Gln Lys Lys 340 345 350 Asn Ile Arg Ile Leu Gln Ala Glu Ala Pro Val Arg Lys Gly Phe Glu 355 360 365 Ser Arg Glu Ile Ser Gly Gly Leu Leu Val Gln Glu Arg Asp Leu Ile 370 375 380 His Ala Glu Gly Asp Asn Ser Ala Asn Trp Thr Leu Ala Ala Gly Ser 385 390 395 400 Ala Val Ser Pro Glu Val Leu Lys Asp Leu Glu Phe Ala Trp Thr Ala 405 410 415 Val Arg Ser Val Lys Ser Asn Ala Ile Leu Leu Ala Lys Asn Gly Ala 420 425 430 Thr Val Gly Val Gly Met Gly Gln Val Asn Arg Val Asp Ser Ala Arg 435 440 445 Leu Ala Val Asp Arg Ala Gly Ala Glu Arg Ala Thr Gly Ser Val Ala 450 455 460 Ala Ser Asp Ala Phe Phe Pro Phe Ala Asp Gly Phe Glu Val Leu Ala 465 470 475 480 Glu Ala Gly Ile Thr Ala Val Val Gln Pro Gly Gly Ser Ile Arg Asp 485 490 495 Asn Glu Val Ile Glu Ala Ala Asn Lys Ala Gly Val Thr Met Tyr Leu 500 505 510 Thr Gly Ala Arg His Phe Ala His 515 520 <210> 945 <211> 1641 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1618) <223> RXN00488 <400> 945 gttgtggaat agcgtgtgag ctgcagcggt tatccgattt aaggacaagc tactaaagtt 60 tagataattg tggacacact atgaggagga actgtcgcac atg aca acc cag agc 115 Met Thr Thr Gln Ser 1 5 cga gtt tct acc gga gga gac aac cca aac aag gtt gcc ctt gtt gga 163 Arg Val Ser Thr Gly Gly Asp Asn Pro Asn Lys Val Ala Leu Val Gly 10 15 20 tta acc ttt gat gac gta ctt ttg ctt cca gat gcg tcg gac gtt gtt 211 Leu Thr Phe Asp Asp Val Leu Leu Leu Pro Asp Ala Ser Asp Val Val 25 30 35 cct tca gag gta gat acc tcg acg cag tta aca cgt aat att cgc ctt 259 Pro Ser Glu Val Asp Thr Ser Thr Gln Leu Thr Arg Asn Ile Arg Leu 40 45 50 aac acc cct att ctt tct gcc gca atg gat act gtc acc gag gct cgc 307 Asn Thr Pro Ile Leu Ser Ala Ala Met Asp Thr Val Thr Glu Ala Arg 55 60 65 atg gct atc ggc atg gca cgc cat ggc ggc att ggt gtt ttg cac cgc 355 Met Ala Ile Gly Met Ala Arg His Gly Gly Ile Gly Val Leu His Arg 70 75 80 85 aac ctg tct att caa gag cag gca gaa aac gtt gag ctg gtg aag cgt 403 Asn Leu Ser Ile Gln Glu Gln Ala Glu Asn Val Glu Leu Val Lys Arg 90 95 100 tct gag tct gga atg gtc act gat cct gtt acc tgt act cct gac atg 451 Ser Glu Ser Gly Met Val Thr Asp Pro Val Thr Cys Thr Pro Asp Met 105 110 115 agc atc caa gaa gtg gat gat ctg tgt gca cgc ttc cgc att tcc ggt 499 Ser Ile Gln Glu Val Asp Asp Leu Cys Ala Arg Phe Arg Ile Ser Gly 120 125 130 ctg cct gtt gtt gat gag gcc gga aag ttg gtt ggt att tgc acc aac 547 Leu Pro Val Val Asp Glu Ala Gly Lys Leu Val Gly Ile Cys Thr Asn 135 140 145 cgc gat atg cgt ttt gaa agc gac atg aac cgt cgt gtc gct gaa gtt 595 Arg Asp Met Arg Phe Glu Ser Asp Met Asn Arg Arg Val Ala Glu Val 150 155 160 165 atg acc cca atg cct ttg gtt gtt gct gaa gag ggc gtc acc aag gag 643 Met Thr Pro Met Pro Leu Val Val Ala Glu Glu Gly Val Thr Lys Glu 170 175 180 cag gct ctt gct ttg ctg tct gca aac aag gtg gag aag ctt cct atc 691 Gln Ala Leu Ala Leu Leu Ser Ala Asn Lys Val Glu Lys Leu Pro Ile 185 190 195 atc gca aag gac ggc aag ctt gtc ggt ctg atc acg gtg aag gac ttc 739 Ile Ala Lys Asp Gly Lys Leu Val Gly Leu Ile Thr Val Lys Asp Phe 200 205 210 gtt aag act gag cag cac ccg aac gca tcc aag gat gca tca ggt cgt 787 Val Lys Thr Glu Gln His Pro Asn Ala Ser Lys Asp Ala Ser Gly Arg 215 220 225 ctg ctg gtt gcg gct ggc atc ggc acg ggc gag gag tca ttc cag cga 835 Leu Leu Val Ala Ala Gly Ile Gly Thr Gly Glu Glu Ser Phe Gln Arg 230 235 240 245 gct ggt gcg ctt gcc gac gcc ggc gtc gac att ttg gtc gta gac tct 883 Ala Gly Ala Leu Ala Asp Ala Gly Val Asp Ile Leu Val Val Asp Ser 250 255 260 gca cac gcc cat agc cgt gga gtt ttg gac atg gtg tcc cgc gtg aag 931 Ala His Ala His Ser Arg Gly Val Leu Asp Met Val Ser Arg Val Lys 265 270 275 aag tcg ttc ccc aag gtc gat atc gtt ggc ggc aac ttg gcg acc cgc 979 Lys Ser Phe Pro Lys Val Asp Ile Val Gly Gly Asn Leu Ala Thr Arg 280 285 290 gag gct gcg cag gcc atg att gaa gct ggc gca gac gct atc aag gtg 1027 Glu Ala Ala Gln Ala Met Ile Glu Ala Gly Ala Asp Ala Ile Lys Val 295 300 305 ggt att ggc cca ggt tct att tgc acc act cgc gtt gtc gca ggt gtc 1075 Gly Ile Gly Pro Gly Ser Ile Cys Thr Thr Arg Val Val Ala Gly Val 310 315 320 325 ggt gca cct cag atc act gcg atc atg gag gca gct gtt cca gct cac 1123 Gly Ala Pro Gln Ile Thr Ala Ile Met Glu Ala Ala Val Pro Ala His 330 335 340 aag gct ggc gtt cct atc atc gcc gat ggc ggc atg cag ttc tct ggt 1171 Lys Ala Gly Val Pro Ile Ile Ala Asp Gly Gly Met Gln Phe Ser Gly 345 350 355 gat atc gct aag gct ttg gct gct ggc gct aac tcc gtg atg ctg ggc 1219 Asp Ile Ala Lys Ala Leu Ala Ala Gly Ala Asn Ser Val Met Leu Gly 360 365 370 tcc atg ctg gct ggt acc gct gag gct cct ggt gag acc atc acc atc 1267 Ser Met Leu Ala Gly Thr Ala Glu Ala Pro Gly Glu Thr Ile Thr Ile 375 380 385 aac ggc aag cag tac aag cgt tac cgc ggc atg ggc tcc atg ggc gct 1315 Asn Gly Lys Gln Tyr Lys Arg Tyr Arg Gly Met Gly Ser Met Gly Ala 390 395 400 405 atg cag ggc cgt gga ctt agt ggt gag aag cgt tcc tac tcc aag gac 1363 Met Gln Gly Arg Gly Leu Ser Gly Glu Lys Arg Ser Tyr Ser Lys Asp 410 415 420 cgt tac ttc cag tct gac gtt aag agc gaa gac aag ctc gtt cca gaa 1411 Arg Tyr Phe Gln Ser Asp Val Lys Ser Glu Asp Lys Leu Val Pro Glu 425 430 435 ggc atc gaa ggt cgc gtg cct ttc cgc ggt ccc atc gga gac atc att 1459 Gly Ile Glu Gly Arg Val Pro Phe Arg Gly Pro Ile Gly Asp Ile Ile 440 445 450 cac cag cag gtc ggt gga ctt cgt gca gca atg ggc tac acc ggt tcc 1507 His Gln Gln Val Gly Gly Leu Arg Ala Ala Met Gly Tyr Thr Gly Ser 455 460 465 tcc acc att gaa gag ctg cac aac gct cgt ttc gtg cag atc acc agc 1555 Ser Thr Ile Glu Glu Leu His Asn Ala Arg Phe Val Gln Ile Thr Ser 470 475 480 485 gcg ggt ctg aag gaa tcc cac ccg cac cac atc cag cag act gtg gaa 1603 Ala Gly Leu Lys Glu Ser His Pro His His Ile Gln Gln Thr Val Glu 490 495 500 gct cct aac tac cac tagattttgc tcacttaaac agc 1641 Ala Pro Asn Tyr His 505 <210> 946 <211> 506 <212> PRT <213> Corynebacterium glutamicum <400> 946 Met Thr Thr Gln Ser Arg Val Ser Thr Gly Gly Asp Asn Pro Asn Lys 1 5 10 15 Val Ala Leu Val Gly Leu Thr Phe Asp Asp Val Leu Leu Leu Pro Asp 20 25 30 Ala Ser Asp Val Val Pro Ser Glu Val Asp Thr Ser Thr Gln Leu Thr 35 40 45 Arg Asn Ile Arg Leu Asn Thr Pro Ile Leu Ser Ala Ala Met Asp Thr 50 55 60 Val Thr Glu Ala Arg Met Ala Ile Gly Met Ala Arg His Gly Gly Ile 65 70 75 80 Gly Val Leu His Arg Asn Leu Ser Ile Gln Glu Gln Ala Glu Asn Val 85 90 95 Glu Leu Val Lys Arg Ser Glu Ser Gly Met Val Thr Asp Pro Val Thr 100 105 110 Cys Thr Pro Asp Met Ser Ile Gln Glu Val Asp Asp Leu Cys Ala Arg 115 120 125 Phe Arg Ile Ser Gly Leu Pro Val Val Asp Glu Ala Gly Lys Leu Val 130 135 140 Gly Ile Cys Thr Asn Arg Asp Met Arg Phe Glu Ser Asp Met Asn Arg 145 150 155 160 Arg Val Ala Glu Val Met Thr Pro Met Pro Leu Val Val Ala Glu Glu 165 170 175 Gly Val Thr Lys Glu Gln Ala Leu Ala Leu Leu Ser Ala Asn Lys Val 180 185 190 Glu Lys Leu Pro Ile Ile Ala Lys Asp Gly Lys Leu Val Gly Leu Ile 195 200 205 Thr Val Lys Asp Phe Val Lys Thr Glu Gln His Pro Asn Ala Ser Lys 210 215 220 Asp Ala Ser Gly Arg Leu Leu Val Ala Ala Gly Ile Gly Thr Gly Glu 225 230 235 240 Glu Ser Phe Gln Arg Ala Gly Ala Leu Ala Asp Ala Gly Val Asp Ile 245 250 255 Leu Val Val Asp Ser Ala His Ala His Ser Arg Gly Val Leu Asp Met 260 265 270 Val Ser Arg Val Lys Lys Ser Phe Pro Lys Val Asp Ile Val Gly Gly 275 280 285 Asn Leu Ala Thr Arg Glu Ala Ala Gln Ala Met Ile Glu Ala Gly Ala 290 295 300 Asp Ala Ile Lys Val Gly Ile Gly Pro Gly Ser Ile Cys Thr Thr Arg 305 310 315 320 Val Val Ala Gly Val Gly Ala Pro Gln Ile Thr Ala Ile Met Glu Ala 325 330 335 Ala Val Pro Ala His Lys Ala Gly Val Pro Ile Ile Ala Asp Gly Gly 340 345 350 Met Gln Phe Ser Gly Asp Ile Ala Lys Ala Leu Ala Ala Gly Ala Asn 355 360 365 Ser Val Met Leu Gly Ser Met Leu Ala Gly Thr Ala Glu Ala Pro Gly 370 375 380 Glu Thr Ile Thr Ile Asn Gly Lys Gln Tyr Lys Arg Tyr Arg Gly Met 385 390 395 400 Gly Ser Met Gly Ala Met Gln Gly Arg Gly Leu Ser Gly Glu Lys Arg 405 410 415 Ser Tyr Ser Lys Asp Arg Tyr Phe Gln Ser Asp Val Lys Ser Glu Asp 420 425 430 Lys Leu Val Pro Glu Gly Ile Glu Gly Arg Val Pro Phe Arg Gly Pro 435 440 445 Ile Gly Asp Ile Ile His Gln Gln Val Gly Gly Leu Arg Ala Ala Met 450 455 460 Gly Tyr Thr Gly Ser Ser Thr Ile Glu Glu Leu His Asn Ala Arg Phe 465 470 475 480 Val Gln Ile Thr Ser Ala Gly Leu Lys Glu Ser His Pro His His Ile 485 490 495 Gln Gln Thr Val Glu Ala Pro Asn Tyr His 500 505 <210> 947 <211> 574 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(574) <223> FRXA00492 <400> 947 gttgtggaat agcgtgtgag ctgcagcggt tatccgattt aaggacaagc tactaaagtt 60 tagataattg tggacacact atgaggagga actgtcgcac atg aca acc cag agc 115 Met Thr Thr Gln Ser 1 5 cga gtt tct acc gga gga gac aac cca aac aag gtt gcc ctt gtt gga 163 Arg Val Ser Thr Gly Gly Asp Asn Pro Asn Lys Val Ala Leu Val Gly 10 15 20 tta acc ttt gat gac gta ctt ttg ctt cca gat gcg tcg gac gtt gtt 211 Leu Thr Phe Asp Asp Val Leu Leu Leu Pro Asp Ala Ser Asp Val Val 25 30 35 cct tca gag gta gat acc tcg acg cag tta aca cgt aat att cgc ctt 259 Pro Ser Glu Val Asp Thr Ser Thr Gln Leu Thr Arg Asn Ile Arg Leu 40 45 50 aac acc cct att ctt tct gcc gca atg gat act gtc acc gag gct cgc 307 Asn Thr Pro Ile Leu Ser Ala Ala Met Asp Thr Val Thr Glu Ala Arg 55 60 65 atg gct atc ggc atg gca cgc cat ggc ggc att ggt gtt ttg cac cgc 355 Met Ala Ile Gly Met Ala Arg His Gly Gly Ile Gly Val Leu His Arg 70 75 80 85 aac ctg tct att caa gag cag gca gaa aac gtt gag ctg gtg aag cgt 403 Asn Leu Ser Ile Gln Glu Gln Ala Glu Asn Val Glu Leu Val Lys Arg 90 95 100 tct gag tct gga atg gtc act gat cct gtt acc tgt act cct gac atg 451 Ser Glu Ser Gly Met Val Thr Asp Pro Val Thr Cys Thr Pro Asp Met 105 110 115 agc atc caa gaa gtg gat gat ctg tgt gca cgc ttc cgc att tcc ggt 499 Ser Ile Gln Glu Val Asp Asp Leu Cys Ala Arg Phe Arg Ile Ser Gly 120 125 130 ctg cct gtt gtt gat gag gcc gga aag ttg gtt ggt att tgc acc aac 547 Leu Pro Val Val Asp Glu Ala Gly Lys Leu Val Gly Ile Cys Thr Asn 135 140 145 cgc gat atg cgt ttt gaa agc gac atg 574 Arg Asp Met Arg Phe Glu Ser Asp Met 150 155 <210> 948 <211> 158 <212> PRT <213> Corynebacterium glutamicum <400> 948 Met Thr Thr Gln Ser Arg Val Ser Thr Gly Gly Asp Asn Pro Asn Lys 1 5 10 15 Val Ala Leu Val Gly Leu Thr Phe Asp Asp Val Leu Leu Leu Pro Asp 20 25 30 Ala Ser Asp Val Val Pro Ser Glu Val Asp Thr Ser Thr Gln Leu Thr 35 40 45 Arg Asn Ile Arg Leu Asn Thr Pro Ile Leu Ser Ala Ala Met Asp Thr 50 55 60 Val Thr Glu Ala Arg Met Ala Ile Gly Met Ala Arg His Gly Gly Ile 65 70 75 80 Gly Val Leu His Arg Asn Leu Ser Ile Gln Glu Gln Ala Glu Asn Val 85 90 95 Glu Leu Val Lys Arg Ser Glu Ser Gly Met Val Thr Asp Pro Val Thr 100 105 110 Cys Thr Pro Asp Met Ser Ile Gln Glu Val Asp Asp Leu Cys Ala Arg 115 120 125 Phe Arg Ile Ser Gly Leu Pro Val Val Asp Glu Ala Gly Lys Leu Val 130 135 140 Gly Ile Cys Thr Asn Arg Asp Met Arg Phe Glu Ser Asp Met 145 150 155 <210> 949 <211> 557 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(534) <223> FRXA00488 <400> 949 cag atc act gcg atc atg gag gca gct gtt cca gct cac aag gct ggc 48 Gln Ile Thr Ala Ile Met Glu Ala Ala Val Pro Ala His Lys Ala Gly 1 5 10 15 gtt cct atc atc gcc gat ggc ggc atg cag ttc tct ggt gat atc gct 96 Val Pro Ile Ile Ala Asp Gly Gly Met Gln Phe Ser Gly Asp Ile Ala 20 25 30 aag gct ttg gct gct ggc gct aac tcc gtg atg ctg ggc tcc atg ctg 144 Lys Ala Leu Ala Ala Gly Ala Asn Ser Val Met Leu Gly Ser Met Leu 35 40 45 gct ggt acc gct gag gct cct ggt gag acc atc acc atc aac ggc aag 192 Ala Gly Thr Ala Glu Ala Pro Gly Glu Thr Ile Thr Ile Asn Gly Lys 50 55 60 cag tac aag cgt tac cgc ggc atg ggc tcc atg ggc gct atg cag ggc 240 Gln Tyr Lys Arg Tyr Arg Gly Met Gly Ser Met Gly Ala Met Gln Gly 65 70 75 80 cgt gga ctt agt ggt gag aag cgt tcc tac tcc aag gac cgt tac ttc 288 Arg Gly Leu Ser Gly Glu Lys Arg Ser Tyr Ser Lys Asp Arg Tyr Phe 85 90 95 cag tct gac gtt aag agc gaa gac aag ctc gtt cca gaa ggc atc gaa 336 Gln Ser Asp Val Lys Ser Glu Asp Lys Leu Val Pro Glu Gly Ile Glu 100 105 110 ggt cgc gtg cct ttc cgc ggt ccc atc gga gac atc att cac cag cag 384 Gly Arg Val Pro Phe Arg Gly Pro Ile Gly Asp Ile Ile His Gln Gln 115 120 125 gtc ggt gga ctt cgt gca gca atg ggc tac acc ggt tcc tcc acc att 432 Val Gly Gly Leu Arg Ala Ala Met Gly Tyr Thr Gly Ser Ser Thr Ile 130 135 140 gaa gag ctg cac aac gct cgt ttc gtg cag atc acc agc gcg ggt ctg 480 Glu Glu Leu His Asn Ala Arg Phe Val Gln Ile Thr Ser Ala Gly Leu 145 150 155 160 aag gaa tcc cac ccg cac cac atc cag cag act gtg gaa gct cct aac 528 Lys Glu Ser His Pro His His Ile Gln Gln Thr Val Glu Ala Pro Asn 165 170 175 tac cac tagattttgc tcacttaaac agc 557 Tyr His <210> 950 <211> 178 <212> PRT <213> Corynebacterium glutamicum <400> 950 Gln Ile Thr Ala Ile Met Glu Ala Ala Val Pro Ala His Lys Ala Gly 1 5 10 15 Val Pro Ile Ile Ala Asp Gly Gly Met Gln Phe Ser Gly Asp Ile Ala 20 25 30 Lys Ala Leu Ala Ala Gly Ala Asn Ser Val Met Leu Gly Ser Met Leu 35 40 45 Ala Gly Thr Ala Glu Ala Pro Gly Glu Thr Ile Thr Ile Asn Gly Lys 50 55 60 Gln Tyr Lys Arg Tyr Arg Gly Met Gly Ser Met Gly Ala Met Gln Gly 65 70 75 80 Arg Gly Leu Ser Gly Glu Lys Arg Ser Tyr Ser Lys Asp Arg Tyr Phe 85 90 95 Gln Ser Asp Val Lys Ser Glu Asp Lys Leu Val Pro Glu Gly Ile Glu 100 105 110 Gly Arg Val Pro Phe Arg Gly Pro Ile Gly Asp Ile Ile His Gln Gln 115 120 125 Val Gly Gly Leu Arg Ala Ala Met Gly Tyr Thr Gly Ser Ser Thr Ile 130 135 140 Glu Glu Leu His Asn Ala Arg Phe Val Gln Ile Thr Ser Ala Gly Leu 145 150 155 160 Lys Glu Ser His Pro His His Ile Gln Gln Thr Val Glu Ala Pro Asn 165 170 175 Tyr His <210> 951 <211> 1554 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1531) <223> RXA02469 <400> 951 cgtcgaaaag cagtagtaaa gcagcaggaa ggtggtggaa agagcaattg aggtaccctt 60 gccgtgttca gggataactg attaatcaac taggagaccc atg cgt ttt ctt aac 115 Met Arg Phe Leu Asn 1 5 aat tcc aat ccg ccc tat gag ctg aca tat tcc gat gtg ttt atg gtg 163 Asn Ser Asn Pro Pro Tyr Glu Leu Thr Tyr Ser Asp Val Phe Met Val 10 15 20 cct tcg cgt tct gac gta ggc tcc cgc atg tcc gtg gat ctg cgc acc 211 Pro Ser Arg Ser Asp Val Gly Ser Arg Met Ser Val Asp Leu Arg Thr 25 30 35 aat gac gga act gga aca acc atc ccg ctc gtt gtg gca aac atg act 259 Asn Asp Gly Thr Gly Thr Thr Ile Pro Leu Val Val Ala Asn Met Thr 40 45 50 gct gtt gct ggc cga cgc atg gct gag acc att gcg cgc cgc ggt ggc 307 Ala Val Ala Gly Arg Arg Met Ala Glu Thr Ile Ala Arg Arg Gly Gly 55 60 65 atg gcg att ctt ccg cag gat gtg ccc gcc gat att gct gca gag act 355 Met Ala Ile Leu Pro Gln Asp Val Pro Ala Asp Ile Ala Ala Glu Thr 70 75 80 85 atc gcg aat gtg aag aaa gcg gac ctg gtt ttt gat acc cca att acc 403 Ile Ala Asn Val Lys Lys Ala Asp Leu Val Phe Asp Thr Pro Ile Thr 90 95 100 gta aaa ccg cac cac acc gtg ggt tat gca cgc aac ttg atc cac aag 451 Val Lys Pro His His Thr Val Gly Tyr Ala Arg Asn Leu Ile His Lys 105 110 115 cgt gcg cac ggt gca gcc att gtt ttg gag ggc gat cag ccg gtc ggc 499 Arg Ala His Gly Ala Ala Ile Val Leu Glu Gly Asp Gln Pro Val Gly 120 125 130 atc gtc acc gac aag gac ctc gaa ggc gca gac aac ttc act cag gtg 547 Ile Val Thr Asp Lys Asp Leu Glu Gly Ala Asp Asn Phe Thr Gln Val 135 140 145 ggc acc ctc atg tcc acc tcc cta ttg acg ctg cct gag gat att tcc 595 Gly Thr Leu Met Ser Thr Ser Leu Leu Thr Leu Pro Glu Asp Ile Ser 150 155 160 165 ccc gaa gac gcc ttc gga atc ctc cac gaa cac agc cgc aaa ctc gcc 643 Pro Glu Asp Ala Phe Gly Ile Leu His Glu His Ser Arg Lys Leu Ala 170 175 180 ccc gtc gtc gcg gct gac ggc tca ctc cgc ggc atc ctc acc cgc acc 691 Pro Val Val Ala Ala Asp Gly Ser Leu Arg Gly Ile Leu Thr Arg Thr 185 190 195 ggc gcc ctg cgc gcc acc atg tac aag ccg gct atc gac gcc aac ggc 739 Gly Ala Leu Arg Ala Thr Met Tyr Lys Pro Ala Ile Asp Ala Asn Gly 200 205 210 cgc ctg cga gtc ggc gcc gcc atc ggc atc aac ggc gac atc gaa gga 787 Arg Leu Arg Val Gly Ala Ala Ile Gly Ile Asn Gly Asp Ile Glu Gly 215 220 225 cgc acc aaa acg ctt ctc gac gcc ggc gcc gac gtt cta gtc gtc gac 835 Arg Thr Lys Thr Leu Leu Asp Ala Gly Ala Asp Val Leu Val Val Asp 230 235 240 245 aca gca cac ggc cac caa tcc acc atg atc agc gcc ctc aaa cgc atc 883 Thr Ala His Gly His Gln Ser Thr Met Ile Ser Ala Leu Lys Arg Ile 250 255 260 cgc gca ctc gac gtc aac gtc ccc atc gtt gct ggc aac gtg gtc acc 931 Arg Ala Leu Asp Val Asn Val Pro Ile Val Ala Gly Asn Val Val Thr 265 270 275 gcc gat ggt gtc cgc gac cta gtt gaa gca ggc gca aac atc atc aag 979 Ala Asp Gly Val Arg Asp Leu Val Glu Ala Gly Ala Asn Ile Ile Lys 280 285 290 gta ggc gtt gga cca ggc gca atg tgc acc acc cgc atg caa acc ggc 1027 Val Gly Val Gly Pro Gly Ala Met Cys Thr Thr Arg Met Gln Thr Gly 295 300 305 gtt ggc cga cca cag ttc tcc gca gtg ctg gaa tgc gca gcc gaa gcc 1075 Val Gly Arg Pro Gln Phe Ser Ala Val Leu Glu Cys Ala Ala Glu Ala 310 315 320 325 cgc aaa ctc ggc gca cac gta tgg gca gac ggc gga gtc cgc gac ccc 1123 Arg Lys Leu Gly Ala His Val Trp Ala Asp Gly Gly Val Arg Asp Pro 330 335 340 cgc gac gtc gcc ctg gca ctc gca gct ggc gcc tcc aac gtg atg gtc 1171 Arg Asp Val Ala Leu Ala Leu Ala Ala Gly Ala Ser Asn Val Met Val 345 350 355 gga tcc tgg ttc tcc gga acc tac gaa tcc ccc ggc gac ctc cgc ttc 1219 Gly Ser Trp Phe Ser Gly Thr Tyr Glu Ser Pro Gly Asp Leu Arg Phe 360 365 370 gaa tcc gac gga cgc atg tac aaa gaa tcc ttc ggt atg gca tcc cgg 1267 Glu Ser Asp Gly Arg Met Tyr Lys Glu Ser Phe Gly Met Ala Ser Arg 375 380 385 cgc gcc gtg gaa agc cga aac caa aag gtc gaa gct ttc gaa aaa gca 1315 Arg Ala Val Glu Ser Arg Asn Gln Lys Val Glu Ala Phe Glu Lys Ala 390 395 400 405 cgc cgc gca atg ttc gaa gaa ggc atc tcc act gcc cgc atc tac att 1363 Arg Arg Ala Met Phe Glu Glu Gly Ile Ser Thr Ala Arg Ile Tyr Ile 410 415 420 gac aaa cgc cac ggc gga gtc gag gac ctg gta gat caa atc atc tcc 1411 Asp Lys Arg His Gly Gly Val Glu Asp Leu Val Asp Gln Ile Ile Ser 425 430 435 ggt gtc cgc tcc tca ttc acc tac gca ggc gcc gat tcg att gaa acc 1459 Gly Val Arg Ser Ser Phe Thr Tyr Ala Gly Ala Asp Ser Ile Glu Thr 440 445 450 ttc ttc gaa cgc gcc acc gtc gga gtt caa tcc acc gaa ggc tac gca 1507 Phe Phe Glu Arg Ala Thr Val Gly Val Gln Ser Thr Glu Gly Tyr Ala 455 460 465 gaa gga aag cca cgc gct tcg cgt taagtgttgt tgtgcctttg aga 1554 Glu Gly Lys Pro Arg Ala Ser Arg 470 475 <210> 952 <211> 477 <212> PRT <213> Corynebacterium glutamicum <400> 952 Met Arg Phe Leu Asn Asn Ser Asn Pro Pro Tyr Glu Leu Thr Tyr Ser 1 5 10 15 Asp Val Phe Met Val Pro Ser Arg Ser Asp Val Gly Ser Arg Met Ser 20 25 30 Val Asp Leu Arg Thr Asn Asp Gly Thr Gly Thr Thr Ile Pro Leu Val 35 40 45 Val Ala Asn Met Thr Ala Val Ala Gly Arg Arg Met Ala Glu Thr Ile 50 55 60 Ala Arg Arg Gly Gly Met Ala Ile Leu Pro Gln Asp Val Pro Ala Asp 65 70 75 80 Ile Ala Ala Glu Thr Ile Ala Asn Val Lys Lys Ala Asp Leu Val Phe 85 90 95 Asp Thr Pro Ile Thr Val Lys Pro His His Thr Val Gly Tyr Ala Arg 100 105 110 Asn Leu Ile His Lys Arg Ala His Gly Ala Ala Ile Val Leu Glu Gly 115 120 125 Asp Gln Pro Val Gly Ile Val Thr Asp Lys Asp Leu Glu Gly Ala Asp 130 135 140 Asn Phe Thr Gln Val Gly Thr Leu Met Ser Thr Ser Leu Leu Thr Leu 145 150 155 160 Pro Glu Asp Ile Ser Pro Glu Asp Ala Phe Gly Ile Leu His Glu His 165 170 175 Ser Arg Lys Leu Ala Pro Val Val Ala Ala Asp Gly Ser Leu Arg Gly 180 185 190 Ile Leu Thr Arg Thr Gly Ala Leu Arg Ala Thr Met Tyr Lys Pro Ala 195 200 205 Ile Asp Ala Asn Gly Arg Leu Arg Val Gly Ala Ala Ile Gly Ile Asn 210 215 220 Gly Asp Ile Glu Gly Arg Thr Lys Thr Leu Leu Asp Ala Gly Ala Asp 225 230 235 240 Val Leu Val Val Asp Thr Ala His Gly His Gln Ser Thr Met Ile Ser 245 250 255 Ala Leu Lys Arg Ile Arg Ala Leu Asp Val Asn Val Pro Ile Val Ala 260 265 270 Gly Asn Val Val Thr Ala Asp Gly Val Arg Asp Leu Val Glu Ala Gly 275 280 285 Ala Asn Ile Ile Lys Val Gly Val Gly Pro Gly Ala Met Cys Thr Thr 290 295 300 Arg Met Gln Thr Gly Val Gly Arg Pro Gln Phe Ser Ala Val Leu Glu 305 310 315 320 Cys Ala Ala Glu Ala Arg Lys Leu Gly Ala His Val Trp Ala Asp Gly 325 330 335 Gly Val Arg Asp Pro Arg Asp Val Ala Leu Ala Leu Ala Ala Gly Ala 340 345 350 Ser Asn Val Met Val Gly Ser Trp Phe Ser Gly Thr Tyr Glu Ser Pro 355 360 365 Gly Asp Leu Arg Phe Glu Ser Asp Gly Arg Met Tyr Lys Glu Ser Phe 370 375 380 Gly Met Ala Ser Arg Arg Ala Val Glu Ser Arg Asn Gln Lys Val Glu 385 390 395 400 Ala Phe Glu Lys Ala Arg Arg Ala Met Phe Glu Glu Gly Ile Ser Thr 405 410 415 Ala Arg Ile Tyr Ile Asp Lys Arg His Gly Gly Val Glu Asp Leu Val 420 425 430 Asp Gln Ile Ile Ser Gly Val Arg Ser Ser Phe Thr Tyr Ala Gly Ala 435 440 445 Asp Ser Ile Glu Thr Phe Phe Glu Arg Ala Thr Val Gly Val Gln Ser 450 455 460 Thr Glu Gly Tyr Ala Glu Gly Lys Pro Arg Ala Ser Arg 465 470 475 <210> 953 <211> 1692 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1669) <223> RXN00487 <400> 953 agggcgccag gggcatccag ccattaaagc ttttcgacga gccctcgccc atgtggccaa 60 agaatcttat ttggaggctc gtctagtaga gtgagttctt gtg agc ctt cag aca 115 Val Ser Leu Gln Thr 1 5 aat cat cgc cca gta ctc gtc gtt gac ttc ggc gca cag tac gcg cag 163 Asn His Arg Pro Val Leu Val Val Asp Phe Gly Ala Gln Tyr Ala Gln 10 15 20 ctg atc gca cgt cgt gtg cgt gag gcc ggc atc tac tcc gaa gtc atc 211 Leu Ile Ala Arg Arg Val Arg Glu Ala Gly Ile Tyr Ser Glu Val Ile 25 30 35 ccg cac acc gcc acc gca gac gat gtg cgc gct aaa aat gca gca gcc 259 Pro His Thr Ala Thr Ala Asp Asp Val Arg Ala Lys Asn Ala Ala Ala 40 45 50 ctc gtc ctt tcc ggt ggc cca tcc tcc gtg tat gcc gag gga gca cca 307 Leu Val Leu Ser Gly Gly Pro Ser Ser Val Tyr Ala Glu Gly Ala Pro 55 60 65 tcc ctt gac gct gag att ctt gat ctc gga ttg cca gta ttt ggc att 355 Ser Leu Asp Ala Glu Ile Leu Asp Leu Gly Leu Pro Val Phe Gly Ile 70 75 80 85 tgc tac ggc ttc caa gcc atg acc cac gcg ctt ggt ggc acc gtt gcc 403 Cys Tyr Gly Phe Gln Ala Met Thr His Ala Leu Gly Gly Thr Val Ala 90 95 100 aac acc ggt aag cgc gaa tac gga cgc acc gac atc aac gtt gcc ggt 451 Asn Thr Gly Lys Arg Glu Tyr Gly Arg Thr Asp Ile Asn Val Ala Gly 105 110 115 ggc gtc ctc cac gaa ggc ctc gaa gcc tgc cac aag gtg tgg atg agc 499 Gly Val Leu His Glu Gly Leu Glu Ala Cys His Lys Val Trp Met Ser 120 125 130 cac ggc gac gcc gtc tct gaa gcc cca gaa ggt ttc gta gtc acc gcg 547 His Gly Asp Ala Val Ser Glu Ala Pro Glu Gly Phe Val Val Thr Ala 135 140 145 tcc tcc gaa ggt gcg cct gtc gca gct ttc gaa aac aag gaa cgc aaa 595 Ser Ser Glu Gly Ala Pro Val Ala Ala Phe Glu Asn Lys Glu Arg Lys 150 155 160 165 atg gct ggc gtg cag tac cac cca gag gta ttg cac tca cca cac ggc 643 Met Ala Gly Val Gln Tyr His Pro Glu Val Leu His Ser Pro His Gly 170 175 180 cag gca gtt ctg acc cgc ttc ctc act gag atc gca ggt cta gag cag 691 Gln Ala Val Leu Thr Arg Phe Leu Thr Glu Ile Ala Gly Leu Glu Gln 185 190 195 aac tgg acc gca gca aac atc gct gaa gaa ctc atc gaa aag gtc cgc 739 Asn Trp Thr Ala Ala Asn Ile Ala Glu Glu Leu Ile Glu Lys Val Arg 200 205 210 gag cag atc ggc gaa gat ggc cgc gct att tgt ggc cta tcc ggt ggt 787 Glu Gln Ile Gly Glu Asp Gly Arg Ala Ile Cys Gly Leu Ser Gly Gly 215 220 225 gtg gac tcc gct gtt gcc ggt gct ttg gtg cag cgc gcc att ggt gac 835 Val Asp Ser Ala Val Ala Gly Ala Leu Val Gln Arg Ala Ile Gly Asp 230 235 240 245 cgt ttg acc tgt gtc ttt gtt gac cac ggt ctg ctg cgt gcc ggt gag 883 Arg Leu Thr Cys Val Phe Val Asp His Gly Leu Leu Arg Ala Gly Glu 250 255 260 cgc gag cag gtg gaa aaa gac ttc gtc gca gca acc ggc gcc aag ctg 931 Arg Glu Gln Val Glu Lys Asp Phe Val Ala Ala Thr Gly Ala Lys Leu 265 270 275 gtt acc gtt gat gag cgc cag gca ttc cta tcc aag ctg gcc gga gtt 979 Val Thr Val Asp Glu Arg Gln Ala Phe Leu Ser Lys Leu Ala Gly Val 280 285 290 acc gaa cca gaa gca aag cgc aag gct atc ggc gct gag ttc atc cgc 1027 Thr Glu Pro Glu Ala Lys Arg Lys Ala Ile Gly Ala Glu Phe Ile Arg 295 300 305 tcc ttc gag cgc gca gtt gcc ggt gtg ctg gaa gaa gct cca gaa ggt 1075 Ser Phe Glu Arg Ala Val Ala Gly Val Leu Glu Glu Ala Pro Glu Gly 310 315 320 325 tcc acc gtg gac ttc ctg gtt cag ggc acc ctg tac cca gac gtc gtg 1123 Ser Thr Val Asp Phe Leu Val Gln Gly Thr Leu Tyr Pro Asp Val Val 330 335 340 gaa tcc ggt ggt gga tct ggt acc gca aac atc aag agc cac cac aac 1171 Glu Ser Gly Gly Gly Ser Gly Thr Ala Asn Ile Lys Ser His His Asn 345 350 355 gtc ggt gga ctg cca gac gat gtg gaa ttc aag ctt gtt gag cca ctg 1219 Val Gly Gly Leu Pro Asp Asp Val Glu Phe Lys Leu Val Glu Pro Leu 360 365 370 cgt gac ctc ttc aaa gac gaa gtc cgt gcc gtt ggc cgt gaa ctt ggc 1267 Arg Asp Leu Phe Lys Asp Glu Val Arg Ala Val Gly Arg Glu Leu Gly 375 380 385 ctg cct gag gaa atc gtt ggc cgc cag cca ttc cca gga cca gga ctt 1315 Leu Pro Glu Glu Ile Val Gly Arg Gln Pro Phe Pro Gly Pro Gly Leu 390 395 400 405 ggt atc cgc atc atc ggt gaa gtc acc gaa gat cgc cta gaa acc ctc 1363 Gly Ile Arg Ile Ile Gly Glu Val Thr Glu Asp Arg Leu Glu Thr Leu 410 415 420 cgc cac gct gac ctg atc gcc cgc acc gag ctc acc gaa gcc gga ctt 1411 Arg His Ala Asp Leu Ile Ala Arg Thr Glu Leu Thr Glu Ala Gly Leu 425 430 435 gac ggc gtg atc tgg cag tgc cca gta gtc ctc ctg gca gat gtc cgc 1459 Asp Gly Val Ile Trp Gln Cys Pro Val Val Leu Leu Ala Asp Val Arg 440 445 450 tct gtt ggt gtt caa ggc gat ggc cgc acc tac gga cac cca atc gtg 1507 Ser Val Gly Val Gln Gly Asp Gly Arg Thr Tyr Gly His Pro Ile Val 455 460 465 ctg cgc cca gtg tct tcc gaa gac gca atg acc gcc gac tgg acc cgc 1555 Leu Arg Pro Val Ser Ser Glu Asp Ala Met Thr Ala Asp Trp Thr Arg 470 475 480 485 ctg cca tac gag gtt ctg gag aag atc tcc acc cgc atc acc aac gaa 1603 Leu Pro Tyr Glu Val Leu Glu Lys Ile Ser Thr Arg Ile Thr Asn Glu 490 495 500 gtt cca gat gtg aac cgc gtg gtg ctg gac gta acc tcc aag cca cca 1651 Val Pro Asp Val Asn Arg Val Val Leu Asp Val Thr Ser Lys Pro Pro 505 510 515 gga acc atc gaa tgg gag taggccttaa atgagccttc gtt 1692 Gly Thr Ile Glu Trp Glu 520 <210> 954 <211> 523 <212> PRT <213> Corynebacterium glutamicum <400> 954 Val Ser Leu Gln Thr Asn His Arg Pro Val Leu Val Val Asp Phe Gly 1 5 10 15 Ala Gln Tyr Ala Gln Leu Ile Ala Arg Arg Val Arg Glu Ala Gly Ile 20 25 30 Tyr Ser Glu Val Ile Pro His Thr Ala Thr Ala Asp Asp Val Arg Ala 35 40 45 Lys Asn Ala Ala Ala Leu Val Leu Ser Gly Gly Pro Ser Ser Val Tyr 50 55 60 Ala Glu Gly Ala Pro Ser Leu Asp Ala Glu Ile Leu Asp Leu Gly Leu 65 70 75 80 Pro Val Phe Gly Ile Cys Tyr Gly Phe Gln Ala Met Thr His Ala Leu 85 90 95 Gly Gly Thr Val Ala Asn Thr Gly Lys Arg Glu Tyr Gly Arg Thr Asp 100 105 110 Ile Asn Val Ala Gly Gly Val Leu His Glu Gly Leu Glu Ala Cys His 115 120 125 Lys Val Trp Met Ser His Gly Asp Ala Val Ser Glu Ala Pro Glu Gly 130 135 140 Phe Val Val Thr Ala Ser Ser Glu Gly Ala Pro Val Ala Ala Phe Glu 145 150 155 160 Asn Lys Glu Arg Lys Met Ala Gly Val Gln Tyr His Pro Glu Val Leu 165 170 175 His Ser Pro His Gly Gln Ala Val Leu Thr Arg Phe Leu Thr Glu Ile 180 185 190 Ala Gly Leu Glu Gln Asn Trp Thr Ala Ala Asn Ile Ala Glu Glu Leu 195 200 205 Ile Glu Lys Val Arg Glu Gln Ile Gly Glu Asp Gly Arg Ala Ile Cys 210 215 220 Gly Leu Ser Gly Gly Val Asp Ser Ala Val Ala Gly Ala Leu Val Gln 225 230 235 240 Arg Ala Ile Gly Asp Arg Leu Thr Cys Val Phe Val Asp His Gly Leu 245 250 255 Leu Arg Ala Gly Glu Arg Glu Gln Val Glu Lys Asp Phe Val Ala Ala 260 265 270 Thr Gly Ala Lys Leu Val Thr Val Asp Glu Arg Gln Ala Phe Leu Ser 275 280 285 Lys Leu Ala Gly Val Thr Glu Pro Glu Ala Lys Arg Lys Ala Ile Gly 290 295 300 Ala Glu Phe Ile Arg Ser Phe Glu Arg Ala Val Ala Gly Val Leu Glu 305 310 315 320 Glu Ala Pro Glu Gly Ser Thr Val Asp Phe Leu Val Gln Gly Thr Leu 325 330 335 Tyr Pro Asp Val Val Glu Ser Gly Gly Gly Ser Gly Thr Ala Asn Ile 340 345 350 Lys Ser His His Asn Val Gly Gly Leu Pro Asp Asp Val Glu Phe Lys 355 360 365 Leu Val Glu Pro Leu Arg Asp Leu Phe Lys Asp Glu Val Arg Ala Val 370 375 380 Gly Arg Glu Leu Gly Leu Pro Glu Glu Ile Val Gly Arg Gln Pro Phe 385 390 395 400 Pro Gly Pro Gly Leu Gly Ile Arg Ile Ile Gly Glu Val Thr Glu Asp 405 410 415 Arg Leu Glu Thr Leu Arg His Ala Asp Leu Ile Ala Arg Thr Glu Leu 420 425 430 Thr Glu Ala Gly Leu Asp Gly Val Ile Trp Gln Cys Pro Val Val Leu 435 440 445 Leu Ala Asp Val Arg Ser Val Gly Val Gln Gly Asp Gly Arg Thr Tyr 450 455 460 Gly His Pro Ile Val Leu Arg Pro Val Ser Ser Glu Asp Ala Met Thr 465 470 475 480 Ala Asp Trp Thr Arg Leu Pro Tyr Glu Val Leu Glu Lys Ile Ser Thr 485 490 495 Arg Ile Thr Asn Glu Val Pro Asp Val Asn Arg Val Val Leu Asp Val 500 505 510 Thr Ser Lys Pro Pro Gly Thr Ile Glu Trp Glu 515 520 <210> 955 <211> 1486 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1486) <223> FRXA00487 <400> 955 agggcgccag gggcatccag ccattaaagc ttttcgacga gccctcgccc atgtggccaa 60 agaatcttat ttggaggctc gtctagtaga gtgagttctt gtg agc ctt cag aca 115 Val Ser Leu Gln Thr 1 5 aat cat cgc cca gta ctc gtc gtt gac ttc ggc gca cag tac gcg cag 163 Asn His Arg Pro Val Leu Val Val Asp Phe Gly Ala Gln Tyr Ala Gln 10 15 20 ctg atc gca cgt cgt gtg cgt gag gcc ggc atc tac tcc gaa gtc atc 211 Leu Ile Ala Arg Arg Val Arg Glu Ala Gly Ile Tyr Ser Glu Val Ile 25 30 35 ccg cac acc gcc acc gca gac gat gtg cgc gct aaa aat gca gca gcc 259 Pro His Thr Ala Thr Ala Asp Asp Val Arg Ala Lys Asn Ala Ala Ala 40 45 50 ctc gtc ctt tcc ggt ggc cca tcc tcc gtg tat gcc gag gga gca cca 307 Leu Val Leu Ser Gly Gly Pro Ser Ser Val Tyr Ala Glu Gly Ala Pro 55 60 65 tcc ctt gac gct gag att ctt gat ctc gga ttg cca gta ttt ggc att 355 Ser Leu Asp Ala Glu Ile Leu Asp Leu Gly Leu Pro Val Phe Gly Ile 70 75 80 85 tgc tac ggc ttc caa gcc atg acc cac gcg ctt ggt ggc acc gtt gcc 403 Cys Tyr Gly Phe Gln Ala Met Thr His Ala Leu Gly Gly Thr Val Ala 90 95 100 aac acc ggt aag cgc gaa tac gga cgc acc gac atc aac gtt gcc ggt 451 Asn Thr Gly Lys Arg Glu Tyr Gly Arg Thr Asp Ile Asn Val Ala Gly 105 110 115 ggc gtc ctc cac gaa ggc ctc gaa gcc tgc cac aag gtg tgg atg agc 499 Gly Val Leu His Glu Gly Leu Glu Ala Cys His Lys Val Trp Met Ser 120 125 130 cac ggc gac gcc gtc tct gaa gcc cca gaa ggt ttc gta gtc acc gcg 547 His Gly Asp Ala Val Ser Glu Ala Pro Glu Gly Phe Val Val Thr Ala 135 140 145 tcc tcc gaa ggt gcg cct gtc gca gct ttc gaa aac aag gaa cgc aaa 595 Ser Ser Glu Gly Ala Pro Val Ala Ala Phe Glu Asn Lys Glu Arg Lys 150 155 160 165 atg gct ggc gtg cag tac cac cca gag gta ttg cac tca cca cac ggc 643 Met Ala Gly Val Gln Tyr His Pro Glu Val Leu His Ser Pro His Gly 170 175 180 cag gca gtt ctg acc cgc ttc ctc act gag atc gca ggt cta gag cag 691 Gln Ala Val Leu Thr Arg Phe Leu Thr Glu Ile Ala Gly Leu Glu Gln 185 190 195 aac tgg acc gca gca aac atc gct gaa gaa ctc atc gaa aag gtc cgc 739 Asn Trp Thr Ala Ala Asn Ile Ala Glu Glu Leu Ile Glu Lys Val Arg 200 205 210 gag cag atc ggc gaa gat ggc cgc gct att tgt ggc cta tcc ggt ggt 787 Glu Gln Ile Gly Glu Asp Gly Arg Ala Ile Cys Gly Leu Ser Gly Gly 215 220 225 gtg gac tcc gct gtt gcc ggt gct ttg gtg cag cgc gcc att ggt gac 835 Val Asp Ser Ala Val Ala Gly Ala Leu Val Gln Arg Ala Ile Gly Asp 230 235 240 245 cgt ttg acc tgt gtc ttt gtt gac cac ggt ctg ctg cgt gcc ggt gag 883 Arg Leu Thr Cys Val Phe Val Asp His Gly Leu Leu Arg Ala Gly Glu 250 255 260 cgc gag cag gtg gaa aaa gac ttc gtc gca gca acc ggc gcc aag ctg 931 Arg Glu Gln Val Glu Lys Asp Phe Val Ala Ala Thr Gly Ala Lys Leu 265 270 275 gtt acc gtt gat gag cgc cag gca ttc cta tcc aag ctg gcc gga gtt 979 Val Thr Val Asp Glu Arg Gln Ala Phe Leu Ser Lys Leu Ala Gly Val 280 285 290 acc gaa cca gaa gca aag cgc aag gct atc ggc gct gag ttc atc cgc 1027 Thr Glu Pro Glu Ala Lys Arg Lys Ala Ile Gly Ala Glu Phe Ile Arg 295 300 305 tcc ttc gag cgc gca gtt gcc ggt gtg ctg gaa gaa gct cca gaa ggt 1075 Ser Phe Glu Arg Ala Val Ala Gly Val Leu Glu Glu Ala Pro Glu Gly 310 315 320 325 tcc acc gtg gac ttc ctg gtt cag ggc acc ctg tac cca gac gtc gtg 1123 Ser Thr Val Asp Phe Leu Val Gln Gly Thr Leu Tyr Pro Asp Val Val 330 335 340 gaa tcc ggt ggt gga tct ggt acc gca aac atc aag agc cac cac aac 1171 Glu Ser Gly Gly Gly Ser Gly Thr Ala Asn Ile Lys Ser His His Asn 345 350 355 gtc ggt gga ctg cca gac gat gtg gaa ttc aag ctt gtt gag cca ctg 1219 Val Gly Gly Leu Pro Asp Asp Val Glu Phe Lys Leu Val Glu Pro Leu 360 365 370 cgt gac ctc ttc aaa gac gaa gtc cgt gcc gtt ggc cgt gaa ctt ggc 1267 Arg Asp Leu Phe Lys Asp Glu Val Arg Ala Val Gly Arg Glu Leu Gly 375 380 385 ctg cct gag gaa atc gtt ggc cgc cag cca ttc cca gga cca gga ctt 1315 Leu Pro Glu Glu Ile Val Gly Arg Gln Pro Phe Pro Gly Pro Gly Leu 390 395 400 405 ggt atc cgc atc atc ggt gaa gtc acc gaa gat cgc cta gaa acc ctc 1363 Gly Ile Arg Ile Ile Gly Glu Val Thr Glu Asp Arg Leu Glu Thr Leu 410 415 420 cgc cac gct gac ctg atc gcc cgc acc gag ctc acc gaa gcc gga ctt 1411 Arg His Ala Asp Leu Ile Ala Arg Thr Glu Leu Thr Glu Ala Gly Leu 425 430 435 gac ggc gtg atc tgg cag tgc cca gta gtc ctc ctg gca gat gtc cgc 1459 Asp Gly Val Ile Trp Gln Cys Pro Val Val Leu Leu Ala Asp Val Arg 440 445 450 tct gtt ggt gtt caa ggc gat ggc cgc 1486 Ser Val Gly Val Gln Gly Asp Gly Arg 455 460 <210> 956 <211> 462 <212> PRT <213> Corynebacterium glutamicum <400> 956 Val Ser Leu Gln Thr Asn His Arg Pro Val Leu Val Val Asp Phe Gly 1 5 10 15 Ala Gln Tyr Ala Gln Leu Ile Ala Arg Arg Val Arg Glu Ala Gly Ile 20 25 30 Tyr Ser Glu Val Ile Pro His Thr Ala Thr Ala Asp Asp Val Arg Ala 35 40 45 Lys Asn Ala Ala Ala Leu Val Leu Ser Gly Gly Pro Ser Ser Val Tyr 50 55 60 Ala Glu Gly Ala Pro Ser Leu Asp Ala Glu Ile Leu Asp Leu Gly Leu 65 70 75 80 Pro Val Phe Gly Ile Cys Tyr Gly Phe Gln Ala Met Thr His Ala Leu 85 90 95 Gly Gly Thr Val Ala Asn Thr Gly Lys Arg Glu Tyr Gly Arg Thr Asp 100 105 110 Ile Asn Val Ala Gly Gly Val Leu His Glu Gly Leu Glu Ala Cys His 115 120 125 Lys Val Trp Met Ser His Gly Asp Ala Val Ser Glu Ala Pro Glu Gly 130 135 140 Phe Val Val Thr Ala Ser Ser Glu Gly Ala Pro Val Ala Ala Phe Glu 145 150 155 160 Asn Lys Glu Arg Lys Met Ala Gly Val Gln Tyr His Pro Glu Val Leu 165 170 175 His Ser Pro His Gly Gln Ala Val Leu Thr Arg Phe Leu Thr Glu Ile 180 185 190 Ala Gly Leu Glu Gln Asn Trp Thr Ala Ala Asn Ile Ala Glu Glu Leu 195 200 205 Ile Glu Lys Val Arg Glu Gln Ile Gly Glu Asp Gly Arg Ala Ile Cys 210 215 220 Gly Leu Ser Gly Gly Val Asp Ser Ala Val Ala Gly Ala Leu Val Gln 225 230 235 240 Arg Ala Ile Gly Asp Arg Leu Thr Cys Val Phe Val Asp His Gly Leu 245 250 255 Leu Arg Ala Gly Glu Arg Glu Gln Val Glu Lys Asp Phe Val Ala Ala 260 265 270 Thr Gly Ala Lys Leu Val Thr Val Asp Glu Arg Gln Ala Phe Leu Ser 275 280 285 Lys Leu Ala Gly Val Thr Glu Pro Glu Ala Lys Arg Lys Ala Ile Gly 290 295 300 Ala Glu Phe Ile Arg Ser Phe Glu Arg Ala Val Ala Gly Val Leu Glu 305 310 315 320 Glu Ala Pro Glu Gly Ser Thr Val Asp Phe Leu Val Gln Gly Thr Leu 325 330 335 Tyr Pro Asp Val Val Glu Ser Gly Gly Gly Ser Gly Thr Ala Asn Ile 340 345 350 Lys Ser His His Asn Val Gly Gly Leu Pro Asp Asp Val Glu Phe Lys 355 360 365 Leu Val Glu Pro Leu Arg Asp Leu Phe Lys Asp Glu Val Arg Ala Val 370 375 380 Gly Arg Glu Leu Gly Leu Pro Glu Glu Ile Val Gly Arg Gln Pro Phe 385 390 395 400 Pro Gly Pro Gly Leu Gly Ile Arg Ile Ile Gly Glu Val Thr Glu Asp 405 410 415 Arg Leu Glu Thr Leu Arg His Ala Asp Leu Ile Ala Arg Thr Glu Leu 420 425 430 Thr Glu Ala Gly Leu Asp Gly Val Ile Trp Gln Cys Pro Val Val Leu 435 440 445 Leu Ala Asp Val Arg Ser Val Gly Val Gln Gly Asp Gly Arg 450 455 460 <210> 957 <211> 693 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(670) <223> RXA02237 <400> 957 gacgagctgg gcattgctca gacccgtcgt cttcgtggac tgggtgaccg tcagcgtcgc 60 gcacttctcg agcgtttcgg cttcgaggat taattcttca gtg tcg ggc gat aac 115 Val Ser Gly Asp Asn 1 5 caa cta gga cgg ctc gta att ctt gcg ggc ccc tca gcg gtc ggt aaa 163 Gln Leu Gly Arg Leu Val Ile Leu Ala Gly Pro Ser Ala Val Gly Lys 10 15 20 tcg act gtg gtt gat cgc ctc cgc aat gac gtt cca aac ctg tat ttc 211 Ser Thr Val Val Asp Arg Leu Arg Asn Asp Val Pro Asn Leu Tyr Phe 25 30 35 agt gtg tcg atg acc act agg gca cct cgt cct ggt gaa gtc gat gga 259 Ser Val Ser Met Thr Thr Arg Ala Pro Arg Pro Gly Glu Val Asp Gly 40 45 50 cgt gac tac ttc tat gtc act gca cag gaa ttt cag gac aaa atc gac 307 Arg Asp Tyr Phe Tyr Val Thr Ala Gln Glu Phe Gln Asp Lys Ile Asp 55 60 65 tgt gga gag atg ctt gaa tgg gca gat atc cac ggc ggt ttg cag cgt 355 Cys Gly Glu Met Leu Glu Trp Ala Asp Ile His Gly Gly Leu Gln Arg 70 75 80 85 tca ggc act cca gca ggt ccc gtc aat gag gct cgc caa aat ggt cgg 403 Ser Gly Thr Pro Ala Gly Pro Val Asn Glu Ala Arg Gln Asn Gly Arg 90 95 100 cca gta ttg gtt gag gtt gat ctt gca gga gcc cga aac atc gct agc 451 Pro Val Leu Val Glu Val Asp Leu Ala Gly Ala Arg Asn Ile Ala Ser 105 110 115 tta att cca gat gca gaa acc atc ttc ctt gct cca cct tca tgg gaa 499 Leu Ile Pro Asp Ala Glu Thr Ile Phe Leu Ala Pro Pro Ser Trp Glu 120 125 130 gtt ttg gtt gaa cgc ctc act gga cgt ggc acc gaa agc gaa gac gtt 547 Val Leu Val Glu Arg Leu Thr Gly Arg Gly Thr Glu Ser Glu Asp Val 135 140 145 att gct cgc agg ctc gag acc gca cgc gaa gaa ttg gct gct cag agc 595 Ile Ala Arg Arg Leu Glu Thr Ala Arg Glu Glu Leu Ala Ala Gln Ser 150 155 160 165 gaa ttt aag cac gtc att atc aat gat gat gtg gat aca gcc gtc aag 643 Glu Phe Lys His Val Ile Ile Asn Asp Asp Val Asp Thr Ala Val Lys 170 175 180 gct att gag gat gtt ctc ctc ggc gct tagccaaaac atagagcggt 690 Ala Ile Glu Asp Val Leu Leu Gly Ala 185 190 agg 693 <210> 958 <211> 190 <212> PRT <213> Corynebacterium glutamicum <400> 958 Val Ser Gly Asp Asn Gln Leu Gly Arg Leu Val Ile Leu Ala Gly Pro 1 5 10 15 Ser Ala Val Gly Lys Ser Thr Val Val Asp Arg Leu Arg Asn Asp Val 20 25 30 Pro Asn Leu Tyr Phe Ser Val Ser Met Thr Thr Arg Ala Pro Arg Pro 35 40 45 Gly Glu Val Asp Gly Arg Asp Tyr Phe Tyr Val Thr Ala Gln Glu Phe 50 55 60 Gln Asp Lys Ile Asp Cys Gly Glu Met Leu Glu Trp Ala Asp Ile His 65 70 75 80 Gly Gly Leu Gln Arg Ser Gly Thr Pro Ala Gly Pro Val Asn Glu Ala 85 90 95 Arg Gln Asn Gly Arg Pro Val Leu Val Glu Val Asp Leu Ala Gly Ala 100 105 110 Arg Asn Ile Ala Ser Leu Ile Pro Asp Ala Glu Thr Ile Phe Leu Ala 115 120 125 Pro Pro Ser Trp Glu Val Leu Val Glu Arg Leu Thr Gly Arg Gly Thr 130 135 140 Glu Ser Glu Asp Val Ile Ala Arg Arg Leu Glu Thr Ala Arg Glu Glu 145 150 155 160 Leu Ala Ala Gln Ser Glu Phe Lys His Val Ile Ile Asn Asp Asp Val 165 170 175 Asp Thr Ala Val Lys Ala Ile Glu Asp Val Leu Leu Gly Ala 180 185 190 <210> 959 <211> 1413 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1390) <223> RXA01446 <400> 959 gatgattaaa aacctcacat gggatagtaa gatgaaataa cgtctgtgtg cgcacacgcg 60 tgcatactcc aacttcatgg atcggatgtg acgtaaacca atg gct gca atc gtt 115 Met Ala Ala Ile Val 1 5 att gtc ggc gct caa tgg ggc gat gaa ggc aaa ggt aag gcc acg gat 163 Ile Val Gly Ala Gln Trp Gly Asp Glu Gly Lys Gly Lys Ala Thr Asp 10 15 20 att ctc ggc gga ctc gtc gat tac gtg gtt aag ccc aat ggc ggt aac 211 Ile Leu Gly Gly Leu Val Asp Tyr Val Val Lys Pro Asn Gly Gly Asn 25 30 35 aac gct gga cac act gtt gtg gtc ggc ggc gag aag tac gag cta aag 259 Asn Ala Gly His Thr Val Val Val Gly Gly Glu Lys Tyr Glu Leu Lys 40 45 50 ctc ctt cct gcc ggc gtc ctc tcc gaa acg gcc acc cca att ttg ggc 307 Leu Leu Pro Ala Gly Val Leu Ser Glu Thr Ala Thr Pro Ile Leu Gly 55 60 65 aac ggc gtt gtg atc aac ctt gag gca ctg ttc gaa gaa atc gac ggc 355 Asn Gly Val Val Ile Asn Leu Glu Ala Leu Phe Glu Glu Ile Asp Gly 70 75 80 85 ctt gag gct cgc ggt gcg gat gca tcc cgc ctg cgc atc tct gca aac 403 Leu Glu Ala Arg Gly Ala Asp Ala Ser Arg Leu Arg Ile Ser Ala Asn 90 95 100 gct cac ctg gtt gct cca tac cac cag gtg atg gac cgt gtt cag gaa 451 Ala His Leu Val Ala Pro Tyr His Gln Val Met Asp Arg Val Gln Glu 105 110 115 cgc ttc ctg ggc aag cgc gca atc ggc acc acc ggc cgt ggc atc ggc 499 Arg Phe Leu Gly Lys Arg Ala Ile Gly Thr Thr Gly Arg Gly Ile Gly 120 125 130 cca acc tac gcg gac aaa gta tcc cgc gtg gga atc cgt gtt caa gac 547 Pro Thr Tyr Ala Asp Lys Val Ser Arg Val Gly Ile Arg Val Gln Asp 135 140 145 att ttc gac gaa tcc atc ctt cgt caa aaa gtc gaa tcc gcc ctg gat 595 Ile Phe Asp Glu Ser Ile Leu Arg Gln Lys Val Glu Ser Ala Leu Asp 150 155 160 165 tac aaa aac cag gtg ctg gtg aag atg tac aac cgc aag gcc atc gtc 643 Tyr Lys Asn Gln Val Leu Val Lys Met Tyr Asn Arg Lys Ala Ile Val 170 175 180 gct gag gaa atc gtg cag tac ttc ctc tcc tac gct gat cgt ctg cgc 691 Ala Glu Glu Ile Val Gln Tyr Phe Leu Ser Tyr Ala Asp Arg Leu Arg 185 190 195 ccc atg gtc atc gat gcc acc ttg gtg ctc aac gag gca ctt gat cag 739 Pro Met Val Ile Asp Ala Thr Leu Val Leu Asn Glu Ala Leu Asp Gln 200 205 210 ggc aag cac gtt ctt atg gaa ggt ggc cag gca acc atg ctc gac gtg 787 Gly Lys His Val Leu Met Glu Gly Gly Gln Ala Thr Met Leu Asp Val 215 220 225 gac cac ggc acc tac cca ttc gtc acc tcc tcc aac cca acc gcc ggt 835 Asp His Gly Thr Tyr Pro Phe Val Thr Ser Ser Asn Pro Thr Ala Gly 230 235 240 245 ggc gca agt gtt ggt tca ggt atc ggc cca acc aag atc acc agc tcc 883 Gly Ala Ser Val Gly Ser Gly Ile Gly Pro Thr Lys Ile Thr Ser Ser 250 255 260 ttg ggt atc atc aag gcc tac acc act cgt gtt ggt gcc ggc cca ttc 931 Leu Gly Ile Ile Lys Ala Tyr Thr Thr Arg Val Gly Ala Gly Pro Phe 265 270 275 cca act gag ctg ttt gat aag tgg ggc gag tac ctg cag acc gtc ggt 979 Pro Thr Glu Leu Phe Asp Lys Trp Gly Glu Tyr Leu Gln Thr Val Gly 280 285 290 ggc gag gtc ggc gtg aac acc ggc cgt aag cgt cgc tgt ggc tgg tac 1027 Gly Glu Val Gly Val Asn Thr Gly Arg Lys Arg Arg Cys Gly Trp Tyr 295 300 305 gac tcc gtg att gct cgt tac gca tcc cgc gtc aac gga ttc acc gac 1075 Asp Ser Val Ile Ala Arg Tyr Ala Ser Arg Val Asn Gly Phe Thr Asp 310 315 320 325 tac ttc ctg acc aag cta gac gtg ctc acc ggc atc ggt gaa atc cca 1123 Tyr Phe Leu Thr Lys Leu Asp Val Leu Thr Gly Ile Gly Glu Ile Pro 330 335 340 atc tgc gta gct tac gac gtt gat ggt gtt cgc cac gat gaa atg cca 1171 Ile Cys Val Ala Tyr Asp Val Asp Gly Val Arg His Asp Glu Met Pro 345 350 355 ctg acc cag tca gag ttc cac cac gca acc cca atc ttt gaa acc atg 1219 Leu Thr Gln Ser Glu Phe His His Ala Thr Pro Ile Phe Glu Thr Met 360 365 370 cct gca tgg gac gaa gac atc acc gac tgc aag acc ttc gag gat ctt 1267 Pro Ala Trp Asp Glu Asp Ile Thr Asp Cys Lys Thr Phe Glu Asp Leu 375 380 385 cca caa aag gcc cag gac tac gtc cga cgt ctg gaa gaa ctc tct ggt 1315 Pro Gln Lys Ala Gln Asp Tyr Val Arg Arg Leu Glu Glu Leu Ser Gly 390 395 400 405 gct cgc ttc tcc tac atc ggt gtt gga cct ggt cgc gat cag acc atc 1363 Ala Arg Phe Ser Tyr Ile Gly Val Gly Pro Gly Arg Asp Gln Thr Ile 410 415 420 gtc ctg cat gac gta cta gct gac aac tagtactgat aaacatcagt 1410 Val Leu His Asp Val Leu Ala Asp Asn 425 430 gag 1413 <210> 960 <211> 430 <212> PRT <213> Corynebacterium glutamicum <400> 960 Met Ala Ala Ile Val Ile Val Gly Ala Gln Trp Gly Asp Glu Gly Lys 1 5 10 15 Gly Lys Ala Thr Asp Ile Leu Gly Gly Leu Val Asp Tyr Val Val Lys 20 25 30 Pro Asn Gly Gly Asn Asn Ala Gly His Thr Val Val Val Gly Gly Glu 35 40 45 Lys Tyr Glu Leu Lys Leu Leu Pro Ala Gly Val Leu Ser Glu Thr Ala 50 55 60 Thr Pro Ile Leu Gly Asn Gly Val Val Ile Asn Leu Glu Ala Leu Phe 65 70 75 80 Glu Glu Ile Asp Gly Leu Glu Ala Arg Gly Ala Asp Ala Ser Arg Leu 85 90 95 Arg Ile Ser Ala Asn Ala His Leu Val Ala Pro Tyr His Gln Val Met 100 105 110 Asp Arg Val Gln Glu Arg Phe Leu Gly Lys Arg Ala Ile Gly Thr Thr 115 120 125 Gly Arg Gly Ile Gly Pro Thr Tyr Ala Asp Lys Val Ser Arg Val Gly 130 135 140 Ile Arg Val Gln Asp Ile Phe Asp Glu Ser Ile Leu Arg Gln Lys Val 145 150 155 160 Glu Ser Ala Leu Asp Tyr Lys Asn Gln Val Leu Val Lys Met Tyr Asn 165 170 175 Arg Lys Ala Ile Val Ala Glu Glu Ile Val Gln Tyr Phe Leu Ser Tyr 180 185 190 Ala Asp Arg Leu Arg Pro Met Val Ile Asp Ala Thr Leu Val Leu Asn 195 200 205 Glu Ala Leu Asp Gln Gly Lys His Val Leu Met Glu Gly Gly Gln Ala 210 215 220 Thr Met Leu Asp Val Asp His Gly Thr Tyr Pro Phe Val Thr Ser Ser 225 230 235 240 Asn Pro Thr Ala Gly Gly Ala Ser Val Gly Ser Gly Ile Gly Pro Thr 245 250 255 Lys Ile Thr Ser Ser Leu Gly Ile Ile Lys Ala Tyr Thr Thr Arg Val 260 265 270 Gly Ala Gly Pro Phe Pro Thr Glu Leu Phe Asp Lys Trp Gly Glu Tyr 275 280 285 Leu Gln Thr Val Gly Gly Glu Val Gly Val Asn Thr Gly Arg Lys Arg 290 295 300 Arg Cys Gly Trp Tyr Asp Ser Val Ile Ala Arg Tyr Ala Ser Arg Val 305 310 315 320 Asn Gly Phe Thr Asp Tyr Phe Leu Thr Lys Leu Asp Val Leu Thr Gly 325 330 335 Ile Gly Glu Ile Pro Ile Cys Val Ala Tyr Asp Val Asp Gly Val Arg 340 345 350 His Asp Glu Met Pro Leu Thr Gln Ser Glu Phe His His Ala Thr Pro 355 360 365 Ile Phe Glu Thr Met Pro Ala Trp Asp Glu Asp Ile Thr Asp Cys Lys 370 375 380 Thr Phe Glu Asp Leu Pro Gln Lys Ala Gln Asp Tyr Val Arg Arg Leu 385 390 395 400 Glu Glu Leu Ser Gly Ala Arg Phe Ser Tyr Ile Gly Val Gly Pro Gly 405 410 415 Arg Asp Gln Thr Ile Val Leu His Asp Val Leu Ala Asp Asn 420 425 430 <210> 961 <211> 1551 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1528) <223> RXA00619 <400> 961 tcaaaggaag acaccattga aggtgtgcgc aaaatcggag aattcatcaa aaaatagcag 60 cgactaggtt agtttcggtt cgtggggaat aataatttgc gtg gct gat aaa aag 115 Val Ala Asp Lys Lys 1 5 aag atc gca aac gtc ctg tcg aac cgt tac gcc tcc gcg gaa ctt tct 163 Lys Ile Ala Asn Val Leu Ser Asn Arg Tyr Ala Ser Ala Glu Leu Ser 10 15 20 aac ctg tgg agt gcc gaa gag aag atc atc atg gag cgc cag ctc tgg 211 Asn Leu Trp Ser Ala Glu Glu Lys Ile Ile Met Glu Arg Gln Leu Trp 25 30 35 atc gcc gtg atg aaa gcc cag aaa gat ttg gga gtt gag atc cct gcc 259 Ile Ala Val Met Lys Ala Gln Lys Asp Leu Gly Val Glu Ile Pro Ala 40 45 50 gag gca att gaa tcc tat gaa gca gtg atc gac cag gtt gat ttg gca 307 Glu Ala Ile Glu Ser Tyr Glu Ala Val Ile Asp Gln Val Asp Leu Ala 55 60 65 agc atc gcc gat cgt gag cgc gtc acc cgc cac gat gtg aag gcc cgc 355 Ser Ile Ala Asp Arg Glu Arg Val Thr Arg His Asp Val Lys Ala Arg 70 75 80 85 atc gaa gaa ttc aat gca ctg gct ggc cat gag cac atc cac aag ggc 403 Ile Glu Glu Phe Asn Ala Leu Ala Gly His Glu His Ile His Lys Gly 90 95 100 atg acc tcc cgc gac ctc acc gaa aat gtt gaa cag ctg cag atc cac 451 Met Thr Ser Arg Asp Leu Thr Glu Asn Val Glu Gln Leu Gln Ile His 105 110 115 cgc tcc ctt gag ctg gtc cgc aac aag ggc att gca gtt gtt gca gct 499 Arg Ser Leu Glu Leu Val Arg Asn Lys Gly Ile Ala Val Val Ala Ala 120 125 130 atc gga tcc cgc gca gcg cag tac caa agc ctg gtc atg gct ggc cgt 547 Ile Gly Ser Arg Ala Ala Gln Tyr Gln Ser Leu Val Met Ala Gly Arg 135 140 145 tcc cac aac gtg gca gcg cag gca act acc ttg ggc aag cgt ttc gca 595 Ser His Asn Val Ala Ala Gln Ala Thr Thr Leu Gly Lys Arg Phe Ala 150 155 160 165 acc gca gct gat gaa atg ctc gtg gca ctt gag cgc gtc acc gaa ctg 643 Thr Ala Ala Asp Glu Met Leu Val Ala Leu Glu Arg Val Thr Glu Leu 170 175 180 ctc aac cgc tac cca ctt cgc gga atc aag ggc cca atg gga acc gcc 691 Leu Asn Arg Tyr Pro Leu Arg Gly Ile Lys Gly Pro Met Gly Thr Ala 185 190 195 caa gac atg ctt gac ctc atg gaa ggc gac gag gct cgt ctc tcc gat 739 Gln Asp Met Leu Asp Leu Met Glu Gly Asp Glu Ala Arg Leu Ser Asp 200 205 210 ctg gaa acc cgc atc gca gca cac ctc ggc ttt gat cgc gtc ttc gac 787 Leu Glu Thr Arg Ile Ala Ala His Leu Gly Phe Asp Arg Val Phe Asp 215 220 225 tcc gtc ggc cag gtc tac cca cgt tcc ctt gac ttc gat gca gta tct 835 Ser Val Gly Gln Val Tyr Pro Arg Ser Leu Asp Phe Asp Ala Val Ser 230 235 240 245 gct ctg gtt cag ctt ggc tcc ggc cca tca tcg ctg tcc cac acc att 883 Ala Leu Val Gln Leu Gly Ser Gly Pro Ser Ser Leu Ser His Thr Ile 250 255 260 cgt ctc atg gcc ggc acc gaa act gtt acc gaa ggt ttt aag gaa ggc 931 Arg Leu Met Ala Gly Thr Glu Thr Val Thr Glu Gly Phe Lys Glu Gly 265 270 275 cag gtc ggt tcc tct gca atg cct cac aag atg aac gct cgc tcc tgt 979 Gln Val Gly Ser Ser Ala Met Pro His Lys Met Asn Ala Arg Ser Cys 280 285 290 gag cgc gtg ggc ggc ctg cag gtt att ctt cgc gga tac ctc acc atg 1027 Glu Arg Val Gly Gly Leu Gln Val Ile Leu Arg Gly Tyr Leu Thr Met 295 300 305 gtt gct gat ctt tcc ggc cag cag tgg aac gaa ggc gat gtc ttc tgc 1075 Val Ala Asp Leu Ser Gly Gln Gln Trp Asn Glu Gly Asp Val Phe Cys 310 315 320 325 tcc gtg atc cgc cgc gtt gca ctg cca gac gca ttc ttc gcg att gac 1123 Ser Val Ile Arg Arg Val Ala Leu Pro Asp Ala Phe Phe Ala Ile Asp 330 335 340 gga atg ttt gaa act ttc ctg aca gtc ctg gat gaa ttc ggt gca ttc 1171 Gly Met Phe Glu Thr Phe Leu Thr Val Leu Asp Glu Phe Gly Ala Phe 345 350 355 cct gcc atg atc gag cgc gaa ctt gag cgt tac ctg cca ttc ctg gca 1219 Pro Ala Met Ile Glu Arg Glu Leu Glu Arg Tyr Leu Pro Phe Leu Ala 360 365 370 act acc cgt atc ctc atg gcc gct gtc cgc gca ggc gtt ggc cgc gaa 1267 Thr Thr Arg Ile Leu Met Ala Ala Val Arg Ala Gly Val Gly Arg Glu 375 380 385 acc gca cac gaa gta atc aag gaa aac gct gtc gcg gtt gcc ctc aac 1315 Thr Ala His Glu Val Ile Lys Glu Asn Ala Val Ala Val Ala Leu Asn 390 395 400 405 atg cgc gaa aat ggc ggt gac cag gac ctt atc cag cgc ctc gct gct 1363 Met Arg Glu Asn Gly Gly Asp Gln Asp Leu Ile Gln Arg Leu Ala Ala 410 415 420 gat gag cgc ctc cca atg agc gaa gct gac ctt gag gca gcg ctg gct 1411 Asp Glu Arg Leu Pro Met Ser Glu Ala Asp Leu Glu Ala Ala Leu Ala 425 430 435 gac cgc cac gcc ttc atc ggt gcc gct gag tcc cag gtc tcc cgt gtg 1459 Asp Arg His Ala Phe Ile Gly Ala Ala Glu Ser Gln Val Ser Arg Val 440 445 450 ctc gac cgc att cag gtg ctt gtc gac gcc cac ccc ggc gcc gca gac 1507 Leu Asp Arg Ile Gln Val Leu Val Asp Ala His Pro Gly Ala Ala Asp 455 460 465 tac cga cca ggt gag att ctt taaaggtttt taacggcgtt cac 1551 Tyr Arg Pro Gly Glu Ile Leu 470 475 <210> 962 <211> 476 <212> PRT <213> Corynebacterium glutamicum <400> 962 Val Ala Asp Lys Lys Lys Ile Ala Asn Val Leu Ser Asn Arg Tyr Ala 1 5 10 15 Ser Ala Glu Leu Ser Asn Leu Trp Ser Ala Glu Glu Lys Ile Ile Met 20 25 30 Glu Arg Gln Leu Trp Ile Ala Val Met Lys Ala Gln Lys Asp Leu Gly 35 40 45 Val Glu Ile Pro Ala Glu Ala Ile Glu Ser Tyr Glu Ala Val Ile Asp 50 55 60 Gln Val Asp Leu Ala Ser Ile Ala Asp Arg Glu Arg Val Thr Arg His 65 70 75 80 Asp Val Lys Ala Arg Ile Glu Glu Phe Asn Ala Leu Ala Gly His Glu 85 90 95 His Ile His Lys Gly Met Thr Ser Arg Asp Leu Thr Glu Asn Val Glu 100 105 110 Gln Leu Gln Ile His Arg Ser Leu Glu Leu Val Arg Asn Lys Gly Ile 115 120 125 Ala Val Val Ala Ala Ile Gly Ser Arg Ala Ala Gln Tyr Gln Ser Leu 130 135 140 Val Met Ala Gly Arg Ser His Asn Val Ala Ala Gln Ala Thr Thr Leu 145 150 155 160 Gly Lys Arg Phe Ala Thr Ala Ala Asp Glu Met Leu Val Ala Leu Glu 165 170 175 Arg Val Thr Glu Leu Leu Asn Arg Tyr Pro Leu Arg Gly Ile Lys Gly 180 185 190 Pro Met Gly Thr Ala Gln Asp Met Leu Asp Leu Met Glu Gly Asp Glu 195 200 205 Ala Arg Leu Ser Asp Leu Glu Thr Arg Ile Ala Ala His Leu Gly Phe 210 215 220 Asp Arg Val Phe Asp Ser Val Gly Gln Val Tyr Pro Arg Ser Leu Asp 225 230 235 240 Phe Asp Ala Val Ser Ala Leu Val Gln Leu Gly Ser Gly Pro Ser Ser 245 250 255 Leu Ser His Thr Ile Arg Leu Met Ala Gly Thr Glu Thr Val Thr Glu 260 265 270 Gly Phe Lys Glu Gly Gln Val Gly Ser Ser Ala Met Pro His Lys Met 275 280 285 Asn Ala Arg Ser Cys Glu Arg Val Gly Gly Leu Gln Val Ile Leu Arg 290 295 300 Gly Tyr Leu Thr Met Val Ala Asp Leu Ser Gly Gln Gln Trp Asn Glu 305 310 315 320 Gly Asp Val Phe Cys Ser Val Ile Arg Arg Val Ala Leu Pro Asp Ala 325 330 335 Phe Phe Ala Ile Asp Gly Met Phe Glu Thr Phe Leu Thr Val Leu Asp 340 345 350 Glu Phe Gly Ala Phe Pro Ala Met Ile Glu Arg Glu Leu Glu Arg Tyr 355 360 365 Leu Pro Phe Leu Ala Thr Thr Arg Ile Leu Met Ala Ala Val Arg Ala 370 375 380 Gly Val Gly Arg Glu Thr Ala His Glu Val Ile Lys Glu Asn Ala Val 385 390 395 400 Ala Val Ala Leu Asn Met Arg Glu Asn Gly Gly Asp Gln Asp Leu Ile 405 410 415 Gln Arg Leu Ala Ala Asp Glu Arg Leu Pro Met Ser Glu Ala Asp Leu 420 425 430 Glu Ala Ala Leu Ala Asp Arg His Ala Phe Ile Gly Ala Ala Glu Ser 435 440 445 Gln Val Ser Arg Val Leu Asp Arg Ile Gln Val Leu Val Asp Ala His 450 455 460 Pro Gly Ala Ala Asp Tyr Arg Pro Gly Glu Ile Leu 465 470 475 <210> 963 <211> 666 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(643) <223> RXA00688 <400> 963 gcggaaccgc aatcttgatt cttgtatctg ttgcactgac cacagtgaag cagattgaga 60 gccagctcct gcaaagcaac tacgaaggac ttctaaaata atg cga ctc gta ctc 115 Met Arg Leu Val Leu 1 5 ctc gga cct ccc ggt gct ggt aag ggc acc cag gct gca att ctc tct 163 Leu Gly Pro Pro Gly Ala Gly Lys Gly Thr Gln Ala Ala Ile Leu Ser 10 15 20 gag aag ctt ggc att cct cac att tct act ggc gat ctt ttc cgc gcc 211 Glu Lys Leu Gly Ile Pro His Ile Ser Thr Gly Asp Leu Phe Arg Ala 25 30 35 aac att ggc gaa ggt acc cct ctg ggt atc gag gcc aag cag tac atc 259 Asn Ile Gly Glu Gly Thr Pro Leu Gly Ile Glu Ala Lys Gln Tyr Ile 40 45 50 gac gct ggc aag ctg gtt cca acc gac gtg act gca cgt atg gtt gct 307 Asp Ala Gly Lys Leu Val Pro Thr Asp Val Thr Ala Arg Met Val Ala 55 60 65 tcc cgc ctt gct gag tcc gat gct gca gaa ggc ttc ctt ttg gat ggt 355 Ser Arg Leu Ala Glu Ser Asp Ala Ala Glu Gly Phe Leu Leu Asp Gly 70 75 80 85 ttc cca cgc acc gtt gag cag gct gac atc ttg gct aac ctg ctt tcc 403 Phe Pro Arg Thr Val Glu Gln Ala Asp Ile Leu Ala Asn Leu Leu Ser 90 95 100 gaa gct ggc cag acc ctc gat ggt gtt gtt aac tac cag gtt tct gaa 451 Glu Ala Gly Gln Thr Leu Asp Gly Val Val Asn Tyr Gln Val Ser Glu 105 110 115 gac gtc gtc gtg gag cgc atg ctg tcc cgt ggt cgc gct gat gac aac 499 Asp Val Val Val Glu Arg Met Leu Ser Arg Gly Arg Ala Asp Asp Asn 120 125 130 gaa gag acc atc cgc acc cgt ctc ggt gtc tac cgc gac gag act gct 547 Glu Glu Thr Ile Arg Thr Arg Leu Gly Val Tyr Arg Asp Glu Thr Ala 135 140 145 cct ctg atc gat cac tac ggt gac aag atc atc aac att gag gct gaa 595 Pro Leu Ile Asp His Tyr Gly Asp Lys Ile Ile Asn Ile Glu Ala Glu 150 155 160 165 ggc gaa gtc gaa gag atc aac gct cgt acc ctc aag gca ctg ggc aaa 643 Gly Glu Val Glu Glu Ile Asn Ala Arg Thr Leu Lys Ala Leu Gly Lys 170 175 180 taagatttct tctctagtgc tgc 666 <210> 964 <211> 181 <212> PRT <213> Corynebacterium glutamicum <400> 964 Met Arg Leu Val Leu Leu Gly Pro Pro Gly Ala Gly Lys Gly Thr Gln 1 5 10 15 Ala Ala Ile Leu Ser Glu Lys Leu Gly Ile Pro His Ile Ser Thr Gly 20 25 30 Asp Leu Phe Arg Ala Asn Ile Gly Glu Gly Thr Pro Leu Gly Ile Glu 35 40 45 Ala Lys Gln Tyr Ile Asp Ala Gly Lys Leu Val Pro Thr Asp Val Thr 50 55 60 Ala Arg Met Val Ala Ser Arg Leu Ala Glu Ser Asp Ala Ala Glu Gly 65 70 75 80 Phe Leu Leu Asp Gly Phe Pro Arg Thr Val Glu Gln Ala Asp Ile Leu 85 90 95 Ala Asn Leu Leu Ser Glu Ala Gly Gln Thr Leu Asp Gly Val Val Asn 100 105 110 Tyr Gln Val Ser Glu Asp Val Val Val Glu Arg Met Leu Ser Arg Gly 115 120 125 Arg Ala Asp Asp Asn Glu Glu Thr Ile Arg Thr Arg Leu Gly Val Tyr 130 135 140 Arg Asp Glu Thr Ala Pro Leu Ile Asp His Tyr Gly Asp Lys Ile Ile 145 150 155 160 Asn Ile Glu Ala Glu Gly Glu Val Glu Glu Ile Asn Ala Arg Thr Leu 165 170 175 Lys Ala Leu Gly Lys 180 <210> 965 <211> 531 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(508) <223> RXA00266 <400> 965 agtaggggat cgtccagcga agcggtcgca gaggctgtga ggaagctcta agtcgactta 60 agtgcgcgaa gcagaccacc attaggtaga atcacccaac atg act gaa cgt act 115 Met Thr Glu Arg Thr 1 5 ctc atc ctt atc aag cca gac ggt gtt acc aac gga cac gtc ggc gaa 163 Leu Ile Leu Ile Lys Pro Asp Gly Val Thr Asn Gly His Val Gly Glu 10 15 20 atc atc gca cgt att gag cgc aag ggc ctg aag ctc gct gct ctg gat 211 Ile Ile Ala Arg Ile Glu Arg Lys Gly Leu Lys Leu Ala Ala Leu Asp 25 30 35 ctg cgt gtt gca gac cgc gag acc gct gaa aag cac tac gaa gag cac 259 Leu Arg Val Ala Asp Arg Glu Thr Ala Glu Lys His Tyr Glu Glu His 40 45 50 gct gac aag cca ttc ttc ggt gag ctc gtt gaa ttc atc acc tct gca 307 Ala Asp Lys Pro Phe Phe Gly Glu Leu Val Glu Phe Ile Thr Ser Ala 55 60 65 cct ctg atc gca ggc atc gtc gaa ggc gag cgt gca atc gat gca tgg 355 Pro Leu Ile Ala Gly Ile Val Glu Gly Glu Arg Ala Ile Asp Ala Trp 70 75 80 85 cgt cag ctt gct ggt ggc acc gac cca gtt gct aag gca acc cca ggc 403 Arg Gln Leu Ala Gly Gly Thr Asp Pro Val Ala Lys Ala Thr Pro Gly 90 95 100 acc atc cgc ggc gat ttc gca ctg act gtt gga gag aac gtt gtt cac 451 Thr Ile Arg Gly Asp Phe Ala Leu Thr Val Gly Glu Asn Val Val His 105 110 115 ggt tct gat tcc cca gag tcc gct gag cgc gag atc tcc atc tgg ttc 499 Gly Ser Asp Ser Pro Glu Ser Ala Glu Arg Glu Ile Ser Ile Trp Phe 120 125 130 cct aac ctg taatttttac ggttagaaaa aaa 531 Pro Asn Leu 135 <210> 966 <211> 136 <212> PRT <213> Corynebacterium glutamicum <400> 966 Met Thr Glu Arg Thr Leu Ile Leu Ile Lys Pro Asp Gly Val Thr Asn 1 5 10 15 Gly His Val Gly Glu Ile Ile Ala Arg Ile Glu Arg Lys Gly Leu Lys 20 25 30 Leu Ala Ala Leu Asp Leu Arg Val Ala Asp Arg Glu Thr Ala Glu Lys 35 40 45 His Tyr Glu Glu His Ala Asp Lys Pro Phe Phe Gly Glu Leu Val Glu 50 55 60 Phe Ile Thr Ser Ala Pro Leu Ile Ala Gly Ile Val Glu Gly Glu Arg 65 70 75 80 Ala Ile Asp Ala Trp Arg Gln Leu Ala Gly Gly Thr Asp Pro Val Ala 85 90 95 Lys Ala Thr Pro Gly Thr Ile Arg Gly Asp Phe Ala Leu Thr Val Gly 100 105 110 Glu Asn Val Val His Gly Ser Asp Ser Pro Glu Ser Ala Glu Arg Glu 115 120 125 Ile Ser Ile Trp Phe Pro Asn Leu 130 135 <210> 967 <211> 1245 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1222) <223> RXA00489 <400> 967 cagcccgatt tcttcattga aatcgggctg tttctggttg tgtcgcgtat ctcgggtaaa 60 gtcttcgtcg tatacgacca tttaagggag gcccgtcaca atg cgt gac cac gtt 115 Met Arg Asp His Val 1 5 gaa atc ggt atc ggc cgt gag gca cga cgc acc tac agc ttg gac gat 163 Glu Ile Gly Ile Gly Arg Glu Ala Arg Arg Thr Tyr Ser Leu Asp Asp 10 15 20 att tct gtc gtt tct agc cgc cgc acc cgt tca tcc aaa gat gtc gac 211 Ile Ser Val Val Ser Ser Arg Arg Thr Arg Ser Ser Lys Asp Val Asp 25 30 35 acc act tgg cat att gac gcc tac aag ttt gat ctg ccg ttc atg aat 259 Thr Thr Trp His Ile Asp Ala Tyr Lys Phe Asp Leu Pro Phe Met Asn 40 45 50 cac cca agt gat gca ttg gca agc cct gag ttt gtc att gaa atg ggc 307 His Pro Ser Asp Ala Leu Ala Ser Pro Glu Phe Val Ile Glu Met Gly 55 60 65 aag cag ggt ggc ctt ggc gtg atc aac gct gag ggt ctg tgg ggt cgc 355 Lys Gln Gly Gly Leu Gly Val Ile Asn Ala Glu Gly Leu Trp Gly Arg 70 75 80 85 cat gct gat ctc gat gag gcg atc gca aag gtg att gct gcg tat gag 403 His Ala Asp Leu Asp Glu Ala Ile Ala Lys Val Ile Ala Ala Tyr Glu 90 95 100 gaa ggc gac cag gct gca gcc act cgc act ctt cag gag ctg cac gca 451 Glu Gly Asp Gln Ala Ala Ala Thr Arg Thr Leu Gln Glu Leu His Ala 105 110 115 gcg cca ctg gat act gag ctg ctg agt gag cgc att gcg cag gtt cgt 499 Ala Pro Leu Asp Thr Glu Leu Leu Ser Glu Arg Ile Ala Gln Val Arg 120 125 130 gat tcc ggt gag atc gtt gct gtg cgc gtg tct cca caa aat gtt cgt 547 Asp Ser Gly Glu Ile Val Ala Val Arg Val Ser Pro Gln Asn Val Arg 135 140 145 gag atc gca cca atc gtc atc aag gca ggt gct gat ctg ctg gtt atc 595 Glu Ile Ala Pro Ile Val Ile Lys Ala Gly Ala Asp Leu Leu Val Ile 150 155 160 165 cag ggc acc ctg atc tct gca gag cac gtc aac acc ggt gga gag gcc 643 Gln Gly Thr Leu Ile Ser Ala Glu His Val Asn Thr Gly Gly Glu Ala 170 175 180 ctg aac cta aag gaa ttc atc ggt tct ttg gat gtt cct gtc atc gct 691 Leu Asn Leu Lys Glu Phe Ile Gly Ser Leu Asp Val Pro Val Ile Ala 185 190 195 ggt ggc gtg aac gat tac acc acc gcg ttg cac atg atg cgt acc ggt 739 Gly Gly Val Asn Asp Tyr Thr Thr Ala Leu His Met Met Arg Thr Gly 200 205 210 gct gtg ggc atc atc gtc ggt ggc ggc gag aac acc aac agc cta gca 787 Ala Val Gly Ile Ile Val Gly Gly Gly Glu Asn Thr Asn Ser Leu Ala 215 220 225 ttg ggc atg gag gta tcc atg gcc act gcg att gct gat gtc gct gcg 835 Leu Gly Met Glu Val Ser Met Ala Thr Ala Ile Ala Asp Val Ala Ala 230 235 240 245 gca cgt cgt gat tac ctg gat gag acc ggt gga cgt tac gtg cac atc 883 Ala Arg Arg Asp Tyr Leu Asp Glu Thr Gly Gly Arg Tyr Val His Ile 250 255 260 att gca gat gga agc att gaa aac tcc ggt gat gta gtc aag gct att 931 Ile Ala Asp Gly Ser Ile Glu Asn Ser Gly Asp Val Val Lys Ala Ile 265 270 275 gcc tgt ggc gca gat gct gtg gtg ctg ggt tca ccg ttg gct cgc gct 979 Ala Cys Gly Ala Asp Ala Val Val Leu Gly Ser Pro Leu Ala Arg Ala 280 285 290 gaa gaa gct gct gga aag ggc tac ttc tgg cca gca gtg gca gcg cac 1027 Glu Glu Ala Ala Gly Lys Gly Tyr Phe Trp Pro Ala Val Ala Ala His 295 300 305 cct cgt ttc cca cgc ggt gtg gtt act gag tcc gtg gac ttg gat gag 1075 Pro Arg Phe Pro Arg Gly Val Val Thr Glu Ser Val Asp Leu Asp Glu 310 315 320 325 gca gca cca agc ttg gag cag att ctg cat ggt ccg tct acg atg ccg 1123 Ala Ala Pro Ser Leu Glu Gln Ile Leu His Gly Pro Ser Thr Met Pro 330 335 340 tgg ggt gtg gaa aac ttc gaa ggt gga tta aag cgt gcg ctg gct aag 1171 Trp Gly Val Glu Asn Phe Glu Gly Gly Leu Lys Arg Ala Leu Ala Lys 345 350 355 tgt ggc tac acc gat ttg aag agc ttc caa aag gta agc ctg cac gtt 1219 Cys Gly Tyr Thr Asp Leu Lys Ser Phe Gln Lys Val Ser Leu His Val 360 365 370 aac taggtgtgtg tactcgcctc ttc 1245 Asn <210> 968 <211> 374 <212> PRT <213> Corynebacterium glutamicum <400> 968 Met Arg Asp His Val Glu Ile Gly Ile Gly Arg Glu Ala Arg Arg Thr 1 5 10 15 Tyr Ser Leu Asp Asp Ile Ser Val Val Ser Ser Arg Arg Thr Arg Ser 20 25 30 Ser Lys Asp Val Asp Thr Thr Trp His Ile Asp Ala Tyr Lys Phe Asp 35 40 45 Leu Pro Phe Met Asn His Pro Ser Asp Ala Leu Ala Ser Pro Glu Phe 50 55 60 Val Ile Glu Met Gly Lys Gln Gly Gly Leu Gly Val Ile Asn Ala Glu 65 70 75 80 Gly Leu Trp Gly Arg His Ala Asp Leu Asp Glu Ala Ile Ala Lys Val 85 90 95 Ile Ala Ala Tyr Glu Glu Gly Asp Gln Ala Ala Ala Thr Arg Thr Leu 100 105 110 Gln Glu Leu His Ala Ala Pro Leu Asp Thr Glu Leu Leu Ser Glu Arg 115 120 125 Ile Ala Gln Val Arg Asp Ser Gly Glu Ile Val Ala Val Arg Val Ser 130 135 140 Pro Gln Asn Val Arg Glu Ile Ala Pro Ile Val Ile Lys Ala Gly Ala 145 150 155 160 Asp Leu Leu Val Ile Gln Gly Thr Leu Ile Ser Ala Glu His Val Asn 165 170 175 Thr Gly Gly Glu Ala Leu Asn Leu Lys Glu Phe Ile Gly Ser Leu Asp 180 185 190 Val Pro Val Ile Ala Gly Gly Val Asn Asp Tyr Thr Thr Ala Leu His 195 200 205 Met Met Arg Thr Gly Ala Val Gly Ile Ile Val Gly Gly Gly Glu Asn 210 215 220 Thr Asn Ser Leu Ala Leu Gly Met Glu Val Ser Met Ala Thr Ala Ile 225 230 235 240 Ala Asp Val Ala Ala Ala Arg Arg Asp Tyr Leu Asp Glu Thr Gly Gly 245 250 255 Arg Tyr Val His Ile Ile Ala Asp Gly Ser Ile Glu Asn Ser Gly Asp 260 265 270 Val Val Lys Ala Ile Ala Cys Gly Ala Asp Ala Val Val Leu Gly Ser 275 280 285 Pro Leu Ala Arg Ala Glu Glu Ala Ala Gly Lys Gly Tyr Phe Trp Pro 290 295 300 Ala Val Ala Ala His Pro Arg Phe Pro Arg Gly Val Val Thr Glu Ser 305 310 315 320 Val Asp Leu Asp Glu Ala Ala Pro Ser Leu Glu Gln Ile Leu His Gly 325 330 335 Pro Ser Thr Met Pro Trp Gly Val Glu Asn Phe Glu Gly Gly Leu Lys 340 345 350 Arg Ala Leu Ala Lys Cys Gly Tyr Thr Asp Leu Lys Ser Phe Gln Lys 355 360 365 Val Ser Leu His Val Asn 370 <210> 969 <211> 1545 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1531) <223> RXN02281 <400> 969 aagatcaaca acgccgccga ggtcaacttg gaaattatca cgtgaggatt cttgcatacg 60 cctataaaag cacagttttg aatccacagg gcatcagggc gtg cag aaa gat agt 115 Val Gln Lys Asp Ser 1 5 gtg gtg cgc atg gaa gca aca acg atc gat gac gca atc gcg aag ctc 163 Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp Ala Ile Ala Lys Leu 10 15 20 att gac atc tac gac acc tcg acc aaa ctg gcc aaa gaa acc ctc aac 211 Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala Lys Glu Thr Leu Asn 25 30 35 aat gag gac tac gcc gca tac gcc gat gtt gtt tac ccc aaa ctc acc 259 Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val Tyr Pro Lys Leu Thr 40 45 50 gtt gac gtg ctg gaa tgg aaa ccc atc gac cgc acc gaa ccc ttc ggc 307 Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg Thr Glu Pro Phe Gly 55 60 65 tat gtg gat cga gcc ggg cga tac tcc gcc acc ttg tcc aaa cca cgc 355 Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr Leu Ser Lys Pro Arg 70 75 80 85 gtg att gag cgt tac ctc cgc gaa caa ctc gag cgt ctc acc agt aat 403 Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu Arg Leu Thr Ser Asn 90 95 100 tat ccc tgc aag att tac gta tct gag tca gat atc cgc atc cca ccg 451 Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp Ile Arg Ile Pro Pro 105 110 115 gag tac att cgc ggc gca cct tcc gct acc gaa gct cgc cgt gct ggt 499 Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu Ala Arg Arg Ala Gly 120 125 130 gat gtt gca gat atc atc cca cgc ccc acc ctg gat gaa gtc cac gac 547 Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu Asp Glu Val His Asp 135 140 145 gca att atc gac ggc gac tgg cac gcc ttc aac ggc ccc gaa ctc ccg 595 Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn Gly Pro Glu Leu Pro 150 155 160 165 ctt ttc cac ttc ggg ccg caa cgc ttc gac atc gcc tgc gcc cgc atc 643 Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile Ala Cys Ala Arg Ile 170 175 180 gag cac tac acc ggc atc aac gtg gaa cac gtg cag aag tac att ctg 691 Glu His Tyr Thr Gly Ile Asn Val Glu His Val Gln Lys Tyr Ile Leu 185 190 195 ttc acc aac tac gcc atg cac acc acc gag ttc gtg cat ttt gcc atg 739 Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe Val His Phe Ala Met 200 205 210 tcc gaa ctc acc tcg gaa gac tcc cgc tac gtg ggt cta tcc ttg cca 787 Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val Gly Leu Ser Leu Pro 215 220 225 aac ggg cag gta att gac cga gag acc gcc acc agc ctc ggt acg gaa 835 Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr Ser Leu Gly Thr Glu 230 235 240 245 acc ctt gat ctg act agc cgt ttc caa atg cct cgt tac gat ctc atc 883 Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro Arg Tyr Asp Leu Ile 250 255 260 acc gaa gcc ggt gac ggt att acc att atc aac atc ggt gtg ggc cca 931 Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn Ile Gly Val Gly Pro 265 270 275 tcc aat gca aaa act atc acc gac tgc ctt gct gtg ctc cgc cca gaa 979 Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala Val Leu Arg Pro Glu 280 285 290 gcc tgg gtg atg atc ggc cac tgt gct ggc atg gac gcc cgc atg cgc 1027 Ala Trp Val Met Ile Gly His Cys Ala Gly Met Asp Ala Arg Met Arg 295 300 305 atc ggc gac ctc atc ctt ggc aac gcc tac cag cgc gaa gac cac att 1075 Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln Arg Glu Asp His Ile 310 315 320 325 ctg aat acc cgc atc cca ctt ggt aat ccg atc ccg gca ata cca gaa 1123 Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile Pro Ala Ile Pro Glu 330 335 340 atc caa aaa gct cta gaa gcc agc gtc gac gaa atc tac gga tcc gac 1171 Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu Ile Tyr Gly Ser Asp 345 350 355 aac agc ctc atg cgc acc ggt acg gtc tta tcc acc gac gac cga aac 1219 Asn Ser Leu Met Arg Thr Gly Thr Val Leu Ser Thr Asp Asp Arg Asn 360 365 370 tgg gaa tgg cac acc cca gaa aac ctc tgg aac tgg ctc aaa gga tcc 1267 Trp Glu Trp His Thr Pro Glu Asn Leu Trp Asn Trp Leu Lys Gly Ser 375 380 385 acc gcc gca gct gtt gac atg gaa tct tcc acc ttg gcc acc aac gga 1315 Thr Ala Ala Ala Val Asp Met Glu Ser Ser Thr Leu Ala Thr Asn Gly 390 395 400 405 tat cga ttc cgc att cca tac ggc acc ctg ctg agc gtc tct gac ctg 1363 Tyr Arg Phe Arg Ile Pro Tyr Gly Thr Leu Leu Ser Val Ser Asp Leu 410 415 420 cca cta cac gca gtg ccg aaa ctt tcc gcg caa gcg cag gcg ttt tac 1411 Pro Leu His Ala Val Pro Lys Leu Ser Ala Gln Ala Gln Ala Phe Tyr 425 430 435 ttc aac tcc aag gaa gcc cac gtc atg tgt gct gtt cgt gca atg gaa 1459 Phe Asn Ser Lys Glu Ala His Val Met Cys Ala Val Arg Ala Met Glu 440 445 450 tac ctg gca gta gat cct gaa cgg ttg cgt acc cgt aaa ctg cgc agg 1507 Tyr Leu Ala Val Asp Pro Glu Arg Leu Arg Thr Arg Lys Leu Arg Arg 455 460 465 acc ttg ggt gag gtg ccg ttt cgc taaagtctcg gaga 1545 Thr Leu Gly Glu Val Pro Phe Arg 470 475 <210> 970 <211> 477 <212> PRT <213> Corynebacterium glutamicum <400> 970 Val Gln Lys Asp Ser Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp 1 5 10 15 Ala Ile Ala Lys Leu Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala 20 25 30 Lys Glu Thr Leu Asn Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val 35 40 45 Tyr Pro Lys Leu Thr Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg 50 55 60 Thr Glu Pro Phe Gly Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr 65 70 75 80 Leu Ser Lys Pro Arg Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu 85 90 95 Arg Leu Thr Ser Asn Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp 100 105 110 Ile Arg Ile Pro Pro Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu 115 120 125 Ala Arg Arg Ala Gly Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu 130 135 140 Asp Glu Val His Asp Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn 145 150 155 160 Gly Pro Glu Leu Pro Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile 165 170 175 Ala Cys Ala Arg Ile Glu His Tyr Thr Gly Ile Asn Val Glu His Val 180 185 190 Gln Lys Tyr Ile Leu Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe 195 200 205 Val His Phe Ala Met Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val 210 215 220 Gly Leu Ser Leu Pro Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr 225 230 235 240 Ser Leu Gly Thr Glu Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro 245 250 255 Arg Tyr Asp Leu Ile Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn 260 265 270 Ile Gly Val Gly Pro Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala 275 280 285 Val Leu Arg Pro Glu Ala Trp Val Met Ile Gly His Cys Ala Gly Met 290 295 300 Asp Ala Arg Met Arg Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln 305 310 315 320 Arg Glu Asp His Ile Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile 325 330 335 Pro Ala Ile Pro Glu Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu 340 345 350 Ile Tyr Gly Ser Asp Asn Ser Leu Met Arg Thr Gly Thr Val Leu Ser 355 360 365 Thr Asp Asp Arg Asn Trp Glu Trp His Thr Pro Glu Asn Leu Trp Asn 370 375 380 Trp Leu Lys Gly Ser Thr Ala Ala Ala Val Asp Met Glu Ser Ser Thr 385 390 395 400 Leu Ala Thr Asn Gly Tyr Arg Phe Arg Ile Pro Tyr Gly Thr Leu Leu 405 410 415 Ser Val Ser Asp Leu Pro Leu His Ala Val Pro Lys Leu Ser Ala Gln 420 425 430 Ala Gln Ala Phe Tyr Phe Asn Ser Lys Glu Ala His Val Met Cys Ala 435 440 445 Val Arg Ala Met Glu Tyr Leu Ala Val Asp Pro Glu Arg Leu Arg Thr 450 455 460 Arg Lys Leu Arg Arg Thr Leu Gly Glu Val Pro Phe Arg 465 470 475 <210> 971 <211> 1191 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1168) <223> FRXA02281 <400> 971 aagatcaaca acgccgccga ggtcaacttg gaaattatca cgtgaggatt cttgcatacg 60 cctataaaag cacagttttg aatccacagg gcatcagggc gtg cag aaa gat agt 115 Val Gln Lys Asp Ser 1 5 gtg gtg cgc atg gaa gca aca acg atc gat gac gca atc gcg aag ctc 163 Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp Ala Ile Ala Lys Leu 10 15 20 att gac atc tac gac acc tcg acc aaa ctg gcc aaa gaa acc ctc aac 211 Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala Lys Glu Thr Leu Asn 25 30 35 aat gag gac tac gcc gca tac gcc gat gtt gtt tac ccc aaa ctc acc 259 Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val Tyr Pro Lys Leu Thr 40 45 50 gtt gac gtg ctg gaa tgg aaa ccc atc gac cgc acc gaa ccc ttc ggc 307 Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg Thr Glu Pro Phe Gly 55 60 65 tat gtg gat cga gcc ggg cga tac tcc gcc acc ttg tcc aaa cca cgc 355 Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr Leu Ser Lys Pro Arg 70 75 80 85 gtg att gag cgt tac ctc cgc gaa caa ctc gag cgt ctc acc agt aat 403 Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu Arg Leu Thr Ser Asn 90 95 100 tat ccc tgc aag att tac gta tct gag tca gat atc cgc atc cca ccg 451 Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp Ile Arg Ile Pro Pro 105 110 115 gag tac att cgc ggc gca cct tcc gct acc gaa gct cgc cgt gct ggt 499 Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu Ala Arg Arg Ala Gly 120 125 130 gat gtt gca gat atc atc cca cgc ccc acc ctg gat gaa gtc cac gac 547 Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu Asp Glu Val His Asp 135 140 145 gca att atc gac ggc gac tgg cac gcc ttc aac ggc ccc gaa ctc ccg 595 Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn Gly Pro Glu Leu Pro 150 155 160 165 ctt ttc cac ttc ggg ccg caa cgc ttc gac atc gcc tgc gcc cgc atc 643 Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile Ala Cys Ala Arg Ile 170 175 180 gag cac tac acc ggc atc aac gtg gaa cac gtg cag aag tac att ctg 691 Glu His Tyr Thr Gly Ile Asn Val Glu His Val Gln Lys Tyr Ile Leu 185 190 195 ttc acc aac tac gcc atg cac acc acc gag ttc gtg cat ttt gcc atg 739 Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe Val His Phe Ala Met 200 205 210 tcc gaa ctc acc tcg gaa gac tcc cgc tac gtg ggt cta tcc ttg cca 787 Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val Gly Leu Ser Leu Pro 215 220 225 aac ggg cag gta att gac cga gag acc gcc acc agc ctc ggt acg gaa 835 Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr Ser Leu Gly Thr Glu 230 235 240 245 acc ctt gat ctg act agc cgt ttc caa atg cct cgt tac gat ctc atc 883 Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro Arg Tyr Asp Leu Ile 250 255 260 acc gaa gcc ggt gac ggt att acc att atc aac atc ggt gtg ggc cca 931 Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn Ile Gly Val Gly Pro 265 270 275 tcc aat gca aaa act atc acc gac tgc ctt gct gtg ctc cgc cca gaa 979 Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala Val Leu Arg Pro Glu 280 285 290 gcc tgg gtg atg atc ggc cac tgt gct ggc atg gac gcc cgc atg cgc 1027 Ala Trp Val Met Ile Gly His Cys Ala Gly Met Asp Ala Arg Met Arg 295 300 305 atc ggc gac ctc atc ctt ggc aac gcc tac cag cgc gaa gac cac att 1075 Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln Arg Glu Asp His Ile 310 315 320 325 ctg aat acc cgc atc cca ctt ggt aat ccg atc ccg gca ata cca gaa 1123 Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile Pro Ala Ile Pro Glu 330 335 340 atc caa aaa gct cta gaa gcc agc gtc gac gaa atc tac gga tcc 1168 Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu Ile Tyr Gly Ser 345 350 355 tagtattcta tagtgtcacc taa 1191 <210> 972 <211> 356 <212> PRT <213> Corynebacterium glutamicum <400> 972 Val Gln Lys Asp Ser Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp 1 5 10 15 Ala Ile Ala Lys Leu Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala 20 25 30 Lys Glu Thr Leu Asn Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val 35 40 45 Tyr Pro Lys Leu Thr Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg 50 55 60 Thr Glu Pro Phe Gly Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr 65 70 75 80 Leu Ser Lys Pro Arg Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu 85 90 95 Arg Leu Thr Ser Asn Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp 100 105 110 Ile Arg Ile Pro Pro Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu 115 120 125 Ala Arg Arg Ala Gly Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu 130 135 140 Asp Glu Val His Asp Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn 145 150 155 160 Gly Pro Glu Leu Pro Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile 165 170 175 Ala Cys Ala Arg Ile Glu His Tyr Thr Gly Ile Asn Val Glu His Val 180 185 190 Gln Lys Tyr Ile Leu Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe 195 200 205 Val His Phe Ala Met Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val 210 215 220 Gly Leu Ser Leu Pro Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr 225 230 235 240 Ser Leu Gly Thr Glu Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro 245 250 255 Arg Tyr Asp Leu Ile Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn 260 265 270 Ile Gly Val Gly Pro Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala 275 280 285 Val Leu Arg Pro Glu Ala Trp Val Met Ile Gly His Cys Ala Gly Met 290 295 300 Asp Ala Arg Met Arg Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln 305 310 315 320 Arg Glu Asp His Ile Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile 325 330 335 Pro Ala Ile Pro Glu Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu 340 345 350 Ile Tyr Gly Ser 355 <210> 973 <211> 1302 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1279) <223> RXA00147 <400> 973 attgcatata atgcaatgaa ttgaataaac tacattcagg gttatcaacc agccaatttc 60 ttttaaaaag gcagacacac gaaaggcgac aacagtcacc gtg agt aaa gac acc 115 Val Ser Lys Asp Thr 1 5 acc acc tac cag gga gtc acc gag atc gga tcc gtt ccg gca tac ctg 163 Thr Thr Tyr Gln Gly Val Thr Glu Ile Gly Ser Val Pro Ala Tyr Leu 10 15 20 gtt ctt gca gac gga cgt acc ttc acc gga ttt ggc ttt gga gct atc 211 Val Leu Ala Asp Gly Arg Thr Phe Thr Gly Phe Gly Phe Gly Ala Ile 25 30 35 ggc acc acc ctt ggt gag gca gtg ttc act acc gcc atg acc ggt tac 259 Gly Thr Thr Leu Gly Glu Ala Val Phe Thr Thr Ala Met Thr Gly Tyr 40 45 50 caa gaa acc atg acc gat cct tcc tat cac cgc cag att gtt gtg gct 307 Gln Glu Thr Met Thr Asp Pro Ser Tyr His Arg Gln Ile Val Val Ala 55 60 65 acc gca cca cag atc ggc aac acc ggc tgg aac gat gag gac aac gag 355 Thr Ala Pro Gln Ile Gly Asn Thr Gly Trp Asn Asp Glu Asp Asn Glu 70 75 80 85 tcc cgc gac ggc aag att tgg gtt gca ggc ctt gtt atc cgc gac ctc 403 Ser Arg Asp Gly Lys Ile Trp Val Ala Gly Leu Val Ile Arg Asp Leu 90 95 100 gca gca cgt gtg tcc aac tgg cgc gcc acc acc tcc ttg cag cag gaa 451 Ala Ala Arg Val Ser Asn Trp Arg Ala Thr Thr Ser Leu Gln Gln Glu 105 110 115 atg gca ggc cag ggc atc gtc ggc atc ggc gga atc gac acc cgc gca 499 Met Ala Gly Gln Gly Ile Val Gly Ile Gly Gly Ile Asp Thr Arg Ala 120 125 130 ctg gtt cgc cac ctg cgc aat gaa ggt tcc att gca gcg ggc atc ttc 547 Leu Val Arg His Leu Arg Asn Glu Gly Ser Ile Ala Ala Gly Ile Phe 135 140 145 tcc ggc gct gac gca cag cgc cca gtt gaa gaa ctc gta gag atc gtc 595 Ser Gly Ala Asp Ala Gln Arg Pro Val Glu Glu Leu Val Glu Ile Val 150 155 160 165 aag aat cag cca gca atg acc ggc gca aac ctc tcc gtt gag gtc tct 643 Lys Asn Gln Pro Ala Met Thr Gly Ala Asn Leu Ser Val Glu Val Ser 170 175 180 gct gat gaa acc tac gtc atc gaa gct gaa ggc gaa gag cgc cac acc 691 Ala Asp Glu Thr Tyr Val Ile Glu Ala Glu Gly Glu Glu Arg His Thr 185 190 195 gtc gtg gcc tac gac ctg ggc att aag caa aac acc cca cgt cgt ttc 739 Val Val Ala Tyr Asp Leu Gly Ile Lys Gln Asn Thr Pro Arg Arg Phe 200 205 210 tct gca cgc ggt gtt cgc acc gtc atc gtg cct gct gaa acc cca ttc 787 Ser Ala Arg Gly Val Arg Thr Val Ile Val Pro Ala Glu Thr Pro Phe 215 220 225 gag gat atc aag cag tac aac cca tca ggc gtg ttc atc tcc aac ggc 835 Glu Asp Ile Lys Gln Tyr Asn Pro Ser Gly Val Phe Ile Ser Asn Gly 230 235 240 245 cct ggc gat cct gca gca gca gac gtc atg gtt gat atc gtc cgc gaa 883 Pro Gly Asp Pro Ala Ala Ala Asp Val Met Val Asp Ile Val Arg Glu 250 255 260 gtt ctt gaa gcc gac att cca ttc ttt ggc atc tgc ttc ggc aac cag 931 Val Leu Glu Ala Asp Ile Pro Phe Phe Gly Ile Cys Phe Gly Asn Gln 265 270 275 att ctt ggc cgc gca ttc ggc atg gag acc tac aag ctg aag ttc ggc 979 Ile Leu Gly Arg Ala Phe Gly Met Glu Thr Tyr Lys Leu Lys Phe Gly 280 285 290 cac cgc ggc atc aac gtt cca gtg aag aac cac atc acc ggc aag atc 1027 His Arg Gly Ile Asn Val Pro Val Lys Asn His Ile Thr Gly Lys Ile 295 300 305 gac atc acc gcc cag aac cac ggc ttc gca ctc aag ggt gaa gca ggc 1075 Asp Ile Thr Ala Gln Asn His Gly Phe Ala Leu Lys Gly Glu Ala Gly 310 315 320 325 cag gaa ttc gag acc gat ttc ggc act gca att gtc acc cac acc tgc 1123 Gln Glu Phe Glu Thr Asp Phe Gly Thr Ala Ile Val Thr His Thr Cys 330 335 340 ctc aac gac ggc gtc gtt gaa ggt att gcg ctg aag tcc gga cgc gca 1171 Leu Asn Asp Gly Val Val Glu Gly Ile Ala Leu Lys Ser Gly Arg Ala 345 350 355 tac tcc gtt cag tac cac cca gag gcc gct gcc ggc cca aat gat gca 1219 Tyr Ser Val Gln Tyr His Pro Glu Ala Ala Ala Gly Pro Asn Asp Ala 360 365 370 agc ccc ctg ttt gac cag ttt gtt gag ctg atg gat gca gac gct cag 1267 Ser Pro Leu Phe Asp Gln Phe Val Glu Leu Met Asp Ala Asp Ala Gln 375 380 385 aag aaa ggc gca taaataacat gccaaagcgt tca 1302 Lys Lys Gly Ala 390 <210> 974 <211> 393 <212> PRT <213> Corynebacterium glutamicum <400> 974 Val Ser Lys Asp Thr Thr Thr Tyr Gln Gly Val Thr Glu Ile Gly Ser 1 5 10 15 Val Pro Ala Tyr Leu Val Leu Ala Asp Gly Arg Thr Phe Thr Gly Phe 20 25 30 Gly Phe Gly Ala Ile Gly Thr Thr Leu Gly Glu Ala Val Phe Thr Thr 35 40 45 Ala Met Thr Gly Tyr Gln Glu Thr Met Thr Asp Pro Ser Tyr His Arg 50 55 60 Gln Ile Val Val Ala Thr Ala Pro Gln Ile Gly Asn Thr Gly Trp Asn 65 70 75 80 Asp Glu Asp Asn Glu Ser Arg Asp Gly Lys Ile Trp Val Ala Gly Leu 85 90 95 Val Ile Arg Asp Leu Ala Ala Arg Val Ser Asn Trp Arg Ala Thr Thr 100 105 110 Ser Leu Gln Gln Glu Met Ala Gly Gln Gly Ile Val Gly Ile Gly Gly 115 120 125 Ile Asp Thr Arg Ala Leu Val Arg His Leu Arg Asn Glu Gly Ser Ile 130 135 140 Ala Ala Gly Ile Phe Ser Gly Ala Asp Ala Gln Arg Pro Val Glu Glu 145 150 155 160 Leu Val Glu Ile Val Lys Asn Gln Pro Ala Met Thr Gly Ala Asn Leu 165 170 175 Ser Val Glu Val Ser Ala Asp Glu Thr Tyr Val Ile Glu Ala Glu Gly 180 185 190 Glu Glu Arg His Thr Val Val Ala Tyr Asp Leu Gly Ile Lys Gln Asn 195 200 205 Thr Pro Arg Arg Phe Ser Ala Arg Gly Val Arg Thr Val Ile Val Pro 210 215 220 Ala Glu Thr Pro Phe Glu Asp Ile Lys Gln Tyr Asn Pro Ser Gly Val 225 230 235 240 Phe Ile Ser Asn Gly Pro Gly Asp Pro Ala Ala Ala Asp Val Met Val 245 250 255 Asp Ile Val Arg Glu Val Leu Glu Ala Asp Ile Pro Phe Phe Gly Ile 260 265 270 Cys Phe Gly Asn Gln Ile Leu Gly Arg Ala Phe Gly Met Glu Thr Tyr 275 280 285 Lys Leu Lys Phe Gly His Arg Gly Ile Asn Val Pro Val Lys Asn His 290 295 300 Ile Thr Gly Lys Ile Asp Ile Thr Ala Gln Asn His Gly Phe Ala Leu 305 310 315 320 Lys Gly Glu Ala Gly Gln Glu Phe Glu Thr Asp Phe Gly Thr Ala Ile 325 330 335 Val Thr His Thr Cys Leu Asn Asp Gly Val Val Glu Gly Ile Ala Leu 340 345 350 Lys Ser Gly Arg Ala Tyr Ser Val Gln Tyr His Pro Glu Ala Ala Ala 355 360 365 Gly Pro Asn Asp Ala Ser Pro Leu Phe Asp Gln Phe Val Glu Leu Met 370 375 380 Asp Ala Asp Ala Gln Lys Lys Gly Ala 385 390 <210> 975 <211> 1059 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1036) <223> RXA00145 <400> 975 ccccaccgca cgcgcggaag acgtttccgt catgcttaca gaaatcgacg gccgcgatgc 60 agtcacgctc acccgagaag actctgaagg ggattcctag atg aag cac ctc cta 115 Met Lys His Leu Leu 1 5 tcc att agc gat ctt tcc aaa gat gag att gtt gga ttg ctg gat gaa 163 Ser Ile Ser Asp Leu Ser Lys Asp Glu Ile Val Gly Leu Leu Asp Glu 10 15 20 gcg gat cgc ttt aag gag gtg ctc gaa gga cgt gaa gta aag aag ctg 211 Ala Asp Arg Phe Lys Glu Val Leu Glu Gly Arg Glu Val Lys Lys Leu 25 30 35 ccc acg ctg cgt ggt cgc acc att ttt acc ttg ttc tat gag aac tcc 259 Pro Thr Leu Arg Gly Arg Thr Ile Phe Thr Leu Phe Tyr Glu Asn Ser 40 45 50 acg cgc acc cgt tcg tcc ttt gaa acc gca gga aag tgg atg agc gcc 307 Thr Arg Thr Arg Ser Ser Phe Glu Thr Ala Gly Lys Trp Met Ser Ala 55 60 65 gat gtg att aac att tcg gcc tca tca tcc agc gtg aag aag ggc gag 355 Asp Val Ile Asn Ile Ser Ala Ser Ser Ser Ser Val Lys Lys Gly Glu 70 75 80 85 tcg ctg aaa gat acc ggc ttg act ttg tcg gca atc ggc gcg gat gcg 403 Ser Leu Lys Asp Thr Gly Leu Thr Leu Ser Ala Ile Gly Ala Asp Ala 90 95 100 atc atc atg cgc cac cca gcc tca ggc gcc gcg cag cag ctt gcg cag 451 Ile Ile Met Arg His Pro Ala Ser Gly Ala Ala Gln Gln Leu Ala Gln 105 110 115 ttc gtc gca cca ggt ggc aac ggc ccc agc gtg atc aac gcg ggt gac 499 Phe Val Ala Pro Gly Gly Asn Gly Pro Ser Val Ile Asn Ala Gly Asp 120 125 130 ggt tcg cac cag cac ccc acc cag gcg ctt ctc gac gct tta acc atc 547 Gly Ser His Gln His Pro Thr Gln Ala Leu Leu Asp Ala Leu Thr Ile 135 140 145 cgg cag cgc acc ggc cgc att gag gga ctc aaa gtt gtc atc gtg ggc 595 Arg Gln Arg Thr Gly Arg Ile Glu Gly Leu Lys Val Val Ile Val Gly 150 155 160 165 gac tgt ttg cac tcc cgg gtg gtg cgc tcc aat gtg gat ctg ctg tcc 643 Asp Cys Leu His Ser Arg Val Val Arg Ser Asn Val Asp Leu Leu Ser 170 175 180 act ttg ggc gca gag gta gtg ctg gtt gct cct ccg aca ctg ctt cct 691 Thr Leu Gly Ala Glu Val Val Leu Val Ala Pro Pro Thr Leu Leu Pro 185 190 195 att ggt gtg gag aac tgg cca gtc cga ttc tcc tac gac atg gac gca 739 Ile Gly Val Glu Asn Trp Pro Val Arg Phe Ser Tyr Asp Met Asp Ala 200 205 210 gaa att gcc gac gcc gac gta gtg atg atg ctg cgc gtt cag caa gaa 787 Glu Ile Ala Asp Ala Asp Val Val Met Met Leu Arg Val Gln Gln Glu 215 220 225 cgc atg cag ggt ggt ttc ttc ccc tca cac cgt gag tac gca acg ctg 835 Arg Met Gln Gly Gly Phe Phe Pro Ser His Arg Glu Tyr Ala Thr Leu 230 235 240 245 tac ggc atg tcc aaa gag cgc gaa gct cgc ctc aag gac tcc gcc atc 883 Tyr Gly Met Ser Lys Glu Arg Glu Ala Arg Leu Lys Asp Ser Ala Ile 250 255 260 atc atg cac ccc ggc ccc atg ctt cgt ggc atg gaa att aac ttc cag 931 Ile Met His Pro Gly Pro Met Leu Arg Gly Met Glu Ile Asn Phe Gln 265 270 275 gtg gca gac gca cca cgc acc gcg gta ctg cag cag gta agc aac ggt 979 Val Ala Asp Ala Pro Arg Thr Ala Val Leu Gln Gln Val Ser Asn Gly 280 285 290 gtg cac atg cgc atg gcc att ttg ttc gcc ctg gtc gca ggc tct gac 1027 Val His Met Arg Met Ala Ile Leu Phe Ala Leu Val Ala Gly Ser Asp 295 300 305 gcg act atc taatcgcgac catctgatcg cga 1059 Ala Thr Ile 310 <210> 976 <211> 312 <212> PRT <213> Corynebacterium glutamicum <400> 976 Met Lys His Leu Leu Ser Ile Ser Asp Leu Ser Lys Asp Glu Ile Val 1 5 10 15 Gly Leu Leu Asp Glu Ala Asp Arg Phe Lys Glu Val Leu Glu Gly Arg 20 25 30 Glu Val Lys Lys Leu Pro Thr Leu Arg Gly Arg Thr Ile Phe Thr Leu 35 40 45 Phe Tyr Glu Asn Ser Thr Arg Thr Arg Ser Ser Phe Glu Thr Ala Gly 50 55 60 Lys Trp Met Ser Ala Asp Val Ile Asn Ile Ser Ala Ser Ser Ser Ser 65 70 75 80 Val Lys Lys Gly Glu Ser Leu Lys Asp Thr Gly Leu Thr Leu Ser Ala 85 90 95 Ile Gly Ala Asp Ala Ile Ile Met Arg His Pro Ala Ser Gly Ala Ala 100 105 110 Gln Gln Leu Ala Gln Phe Val Ala Pro Gly Gly Asn Gly Pro Ser Val 115 120 125 Ile Asn Ala Gly Asp Gly Ser His Gln His Pro Thr Gln Ala Leu Leu 130 135 140 Asp Ala Leu Thr Ile Arg Gln Arg Thr Gly Arg Ile Glu Gly Leu Lys 145 150 155 160 Val Val Ile Val Gly Asp Cys Leu His Ser Arg Val Val Arg Ser Asn 165 170 175 Val Asp Leu Leu Ser Thr Leu Gly Ala Glu Val Val Leu Val Ala Pro 180 185 190 Pro Thr Leu Leu Pro Ile Gly Val Glu Asn Trp Pro Val Arg Phe Ser 195 200 205 Tyr Asp Met Asp Ala Glu Ile Ala Asp Ala Asp Val Val Met Met Leu 210 215 220 Arg Val Gln Gln Glu Arg Met Gln Gly Gly Phe Phe Pro Ser His Arg 225 230 235 240 Glu Tyr Ala Thr Leu Tyr Gly Met Ser Lys Glu Arg Glu Ala Arg Leu 245 250 255 Lys Asp Ser Ala Ile Ile Met His Pro Gly Pro Met Leu Arg Gly Met 260 265 270 Glu Ile Asn Phe Gln Val Ala Asp Ala Pro Arg Thr Ala Val Leu Gln 275 280 285 Gln Val Ser Asn Gly Val His Met Arg Met Ala Ile Leu Phe Ala Leu 290 295 300 Val Ala Gly Ser Asp Ala Thr Ile 305 310 <210> 977 <211> 1464 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1441) <223> RXA00146 <400> 977 atggccattt tgttcgccct ggtcgcaggc tctgacgcga ctatctaatc gcgaccatct 60 gatcgcgaaa ttctagaaaa ggtaacgagg gattaaagaa gtg gtt gac agc aac 115 Val Val Asp Ser Asn 1 5 acc cag tat cca gaa acc ggc gca ctg gca ccg gct cct gca gac tca 163 Thr Gln Tyr Pro Glu Thr Gly Ala Leu Ala Pro Ala Pro Ala Asp Ser 10 15 20 ctc cta atc agc aac gtt ttg gtc tac ggc gaa ggc gag cca acg aat 211 Leu Leu Ile Ser Asn Val Leu Val Tyr Gly Glu Gly Glu Pro Thr Asn 25 30 35 gtg ttt gtt aaa gat ggt gtg atc gca gct atc ggc ggc act cat gag 259 Val Phe Val Lys Asp Gly Val Ile Ala Ala Ile Gly Gly Thr His Glu 40 45 50 gct gac cgc acc atc gac ggc aat ggg gga gtt ctc ctt cca ggt ttc 307 Ala Asp Arg Thr Ile Asp Gly Asn Gly Gly Val Leu Leu Pro Gly Phe 55 60 65 gtg gac atg cac gtt cac ctg cgt gag cca ggc cgc gaa gac act gaa 355 Val Asp Met His Val His Leu Arg Glu Pro Gly Arg Glu Asp Thr Glu 70 75 80 85 acc att gcc act ggt tct gcc gcc gca gcc aag ggc gga ttc acc gca 403 Thr Ile Ala Thr Gly Ser Ala Ala Ala Ala Lys Gly Gly Phe Thr Ala 90 95 100 gta ttc acc atg gcg aac acc act cca gtg atg gat cag ccg gtt atc 451 Val Phe Thr Met Ala Asn Thr Thr Pro Val Met Asp Gln Pro Val Ile 105 110 115 gcg gaa tcc gta tgg ttc aag ggc caa aac att ggc ctg tgc gac gtg 499 Ala Glu Ser Val Trp Phe Lys Gly Gln Asn Ile Gly Leu Cys Asp Val 120 125 130 cat cca gtt gga tcc atc acc aag ggt ctt gag ggc aag gag ctt act 547 His Pro Val Gly Ser Ile Thr Lys Gly Leu Glu Gly Lys Glu Leu Thr 135 140 145 gag ttc ggc atg atg gct cgc tct gaa gcc aag gtg cgc atg ttc tct 595 Glu Phe Gly Met Met Ala Arg Ser Glu Ala Lys Val Arg Met Phe Ser 150 155 160 165 gat gat ggc aag tgc gtc gat gat cct cag gtc atg cgc cgc gcg ctg 643 Asp Asp Gly Lys Cys Val Asp Asp Pro Gln Val Met Arg Arg Ala Leu 170 175 180 gaa tac gcc aag ggc atg gac gtt ttg atc gcc cag cac gct gag gat 691 Glu Tyr Ala Lys Gly Met Asp Val Leu Ile Ala Gln His Ala Glu Asp 185 190 195 cac cgc ctg act gag ggc gct tca gca cac gag ggt gaa aac gca gct 739 His Arg Leu Thr Glu Gly Ala Ser Ala His Glu Gly Glu Asn Ala Ala 200 205 210 cgt ctg ggt ctg cgc ggc tgg cca cgt gtg gct gag gaa tcc atc gtg 787 Arg Leu Gly Leu Arg Gly Trp Pro Arg Val Ala Glu Glu Ser Ile Val 215 220 225 gtg cgc gat gcc atc atg gct cgt gac tac ggc aac cgc gtg cac atc 835 Val Arg Asp Ala Ile Met Ala Arg Asp Tyr Gly Asn Arg Val His Ile 230 235 240 245 tgc cac gcc tcc act gaa ggc acc gtg gag ttg ctt cgt tgg gct aag 883 Cys His Ala Ser Thr Glu Gly Thr Val Glu Leu Leu Arg Trp Ala Lys 250 255 260 tcc cag ggc att cca atc acc gcg gaa gtc acc ccg cac cac ctc acc 931 Ser Gln Gly Ile Pro Ile Thr Ala Glu Val Thr Pro His His Leu Thr 265 270 275 ttg acc gat gag cgc ctg gaa acc tac gac gcg gtc aac aaa gtc aat 979 Leu Thr Asp Glu Arg Leu Glu Thr Tyr Asp Ala Val Asn Lys Val Asn 280 285 290 ccg cca ctg cgc gaa agc cgc gat gcc gaa gcg ctc aag aag gcg ctt 1027 Pro Pro Leu Arg Glu Ser Arg Asp Ala Glu Ala Leu Lys Lys Ala Leu 295 300 305 ctc gac ggc acc atc gat gtt gtt gca acc gac cac gct cct cac ggt 1075 Leu Asp Gly Thr Ile Asp Val Val Ala Thr Asp His Ala Pro His Gly 310 315 320 325 tcc gaa gat aag tgc tgt gaa ttc gaa aac gcc aag cca ggc atg ctc 1123 Ser Glu Asp Lys Cys Cys Glu Phe Glu Asn Ala Lys Pro Gly Met Leu 330 335 340 gga ttg gaa acc tca ctg tcc atc atc gtg gac acc ttc gtt gcc acc 1171 Gly Leu Glu Thr Ser Leu Ser Ile Ile Val Asp Thr Phe Val Ala Thr 345 350 355 gga ctt gca gac tgg cgc ttt gtt gcg cgc gtg atg agt gaa cgc cca 1219 Gly Leu Ala Asp Trp Arg Phe Val Ala Arg Val Met Ser Glu Arg Pro 360 365 370 gca gaa atc acc cgt cta cca ggc cag ggt cgc cca atc gca gaa ggt 1267 Ala Glu Ile Thr Arg Leu Pro Gly Gln Gly Arg Pro Ile Ala Glu Gly 375 380 385 gag cca gca aac ctc gcg att gtt gat cca gga aaa acc tgg aca gca 1315 Glu Pro Ala Asn Leu Ala Ile Val Asp Pro Gly Lys Thr Trp Thr Ala 390 395 400 405 tcc ggt gca gac ttt gcg tcc aag gct gaa aat acc cca ttt gag ggc 1363 Ser Gly Ala Asp Phe Ala Ser Lys Ala Glu Asn Thr Pro Phe Glu Gly 410 415 420 caa gaa ttc agt gcc aag gtc aca cac acc gtg ctt cgt ggc aag gtg 1411 Gln Glu Phe Ser Ala Lys Val Thr His Thr Val Leu Arg Gly Lys Val 425 430 435 act tgt gca gac gga gtt gca caa aac gct taacgggtgg gtgcatagta 1461 Thr Cys Ala Asp Gly Val Ala Gln Asn Ala 440 445 tgc 1464 <210> 978 <211> 447 <212> PRT <213> Corynebacterium glutamicum <400> 978 Val Val Asp Ser Asn Thr Gln Tyr Pro Glu Thr Gly Ala Leu Ala Pro 1 5 10 15 Ala Pro Ala Asp Ser Leu Leu Ile Ser Asn Val Leu Val Tyr Gly Glu 20 25 30 Gly Glu Pro Thr Asn Val Phe Val Lys Asp Gly Val Ile Ala Ala Ile 35 40 45 Gly Gly Thr His Glu Ala Asp Arg Thr Ile Asp Gly Asn Gly Gly Val 50 55 60 Leu Leu Pro Gly Phe Val Asp Met His Val His Leu Arg Glu Pro Gly 65 70 75 80 Arg Glu Asp Thr Glu Thr Ile Ala Thr Gly Ser Ala Ala Ala Ala Lys 85 90 95 Gly Gly Phe Thr Ala Val Phe Thr Met Ala Asn Thr Thr Pro Val Met 100 105 110 Asp Gln Pro Val Ile Ala Glu Ser Val Trp Phe Lys Gly Gln Asn Ile 115 120 125 Gly Leu Cys Asp Val His Pro Val Gly Ser Ile Thr Lys Gly Leu Glu 130 135 140 Gly Lys Glu Leu Thr Glu Phe Gly Met Met Ala Arg Ser Glu Ala Lys 145 150 155 160 Val Arg Met Phe Ser Asp Asp Gly Lys Cys Val Asp Asp Pro Gln Val 165 170 175 Met Arg Arg Ala Leu Glu Tyr Ala Lys Gly Met Asp Val Leu Ile Ala 180 185 190 Gln His Ala Glu Asp His Arg Leu Thr Glu Gly Ala Ser Ala His Glu 195 200 205 Gly Glu Asn Ala Ala Arg Leu Gly Leu Arg Gly Trp Pro Arg Val Ala 210 215 220 Glu Glu Ser Ile Val Val Arg Asp Ala Ile Met Ala Arg Asp Tyr Gly 225 230 235 240 Asn Arg Val His Ile Cys His Ala Ser Thr Glu Gly Thr Val Glu Leu 245 250 255 Leu Arg Trp Ala Lys Ser Gln Gly Ile Pro Ile Thr Ala Glu Val Thr 260 265 270 Pro His His Leu Thr Leu Thr Asp Glu Arg Leu Glu Thr Tyr Asp Ala 275 280 285 Val Asn Lys Val Asn Pro Pro Leu Arg Glu Ser Arg Asp Ala Glu Ala 290 295 300 Leu Lys Lys Ala Leu Leu Asp Gly Thr Ile Asp Val Val Ala Thr Asp 305 310 315 320 His Ala Pro His Gly Ser Glu Asp Lys Cys Cys Glu Phe Glu Asn Ala 325 330 335 Lys Pro Gly Met Leu Gly Leu Glu Thr Ser Leu Ser Ile Ile Val Asp 340 345 350 Thr Phe Val Ala Thr Gly Leu Ala Asp Trp Arg Phe Val Ala Arg Val 355 360 365 Met Ser Glu Arg Pro Ala Glu Ile Thr Arg Leu Pro Gly Gln Gly Arg 370 375 380 Pro Ile Ala Glu Gly Glu Pro Ala Asn Leu Ala Ile Val Asp Pro Gly 385 390 395 400 Lys Thr Trp Thr Ala Ser Gly Ala Asp Phe Ala Ser Lys Ala Glu Asn 405 410 415 Thr Pro Phe Glu Gly Gln Glu Phe Ser Ala Lys Val Thr His Thr Val 420 425 430 Leu Arg Gly Lys Val Thr Cys Ala Asp Gly Val Ala Gln Asn Ala 435 440 445 <210> 979 <211> 1025 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1002) <223> RXA02208 <400> 979 ctc gga gtc gtc gac ggc gtc gca cct cta aac cgc acc atg gaa aaa 48 Leu Gly Val Val Asp Gly Val Ala Pro Leu Asn Arg Thr Met Glu Lys 1 5 10 15 atc atc gca gtg cac gat gat tcc ctc tcc cag gaa gtc ttc ggc gtc 96 Ile Ile Ala Val His Asp Asp Ser Leu Ser Gln Glu Val Phe Gly Val 20 25 30 acc ttc cca cga cca cta ggc ctc gcc gca ggt ttc gac aaa aac gca 144 Thr Phe Pro Arg Pro Leu Gly Leu Ala Ala Gly Phe Asp Lys Asn Ala 35 40 45 tca atg gct gat gcc tgg ggt gcc gtt gga ttc gga tac gcc gaa ctt 192 Ser Met Ala Asp Ala Trp Gly Ala Val Gly Phe Gly Tyr Ala Glu Leu 50 55 60 ggc acc gtc acc gcc ttc cca cag cca gga aac ccc acc ccg cgc ctt 240 Gly Thr Val Thr Ala Phe Pro Gln Pro Gly Asn Pro Thr Pro Arg Leu 65 70 75 80 ttc cgc ctg cct gcc gac aaa gct atc ttg aac cgc atg gga ttc aac 288 Phe Arg Leu Pro Ala Asp Lys Ala Ile Leu Asn Arg Met Gly Phe Asn 85 90 95 aac ctg ggt gca gca gaa gtc gca aaa aac ctg cgc aac cgg aaa tcc 336 Asn Leu Gly Ala Ala Glu Val Ala Lys Asn Leu Arg Asn Arg Lys Ser 100 105 110 acc gat gtc atc ggc atc aac atc ggt aaa acc aaa gtg gtt ccc gct 384 Thr Asp Val Ile Gly Ile Asn Ile Gly Lys Thr Lys Val Val Pro Ala 115 120 125 gaa cac gca gta gat gac tac cgc cgt tct gca tct ttg tta ggt gat 432 Glu His Ala Val Asp Asp Tyr Arg Arg Ser Ala Ser Leu Leu Gly Asp 130 135 140 ctt gct gat tac ctg gtt gtc aac gtt tcc tcc ccc aac act ccg ggt 480 Leu Ala Asp Tyr Leu Val Val Asn Val Ser Ser Pro Asn Thr Pro Gly 145 150 155 160 ctc cgc gat ctg cag gct gtg gaa tct ttg cga cca atc ctc gcc gca 528 Leu Arg Asp Leu Gln Ala Val Glu Ser Leu Arg Pro Ile Leu Ala Ala 165 170 175 gtg cag gaa tcc acc acc gtc cca gtc ttg gtg aaa atc gca cca gac 576 Val Gln Glu Ser Thr Thr Val Pro Val Leu Val Lys Ile Ala Pro Asp 180 185 190 ctc tcc gac gaa gac atc gac gcc gta gct gac ctg gca gtt gag ctc 624 Leu Ser Asp Glu Asp Ile Asp Ala Val Ala Asp Leu Ala Val Glu Leu 195 200 205 aaa ctc gcc gga atc gta gcc acc aat acc acc att tcc cgc gaa ggc 672 Lys Leu Ala Gly Ile Val Ala Thr Asn Thr Thr Ile Ser Arg Glu Gly 210 215 220 ctc aac act cct tca ggt gaa gtc gaa gcc atg ggt gct ggc gga atc 720 Leu Asn Thr Pro Ser Gly Glu Val Glu Ala Met Gly Ala Gly Gly Ile 225 230 235 240 tcc ggt gct cca gta gca gcc cga tct ttg gag gta ctc aag cgc ctc 768 Ser Gly Ala Pro Val Ala Ala Arg Ser Leu Glu Val Leu Lys Arg Leu 245 250 255 tac gca cgg gta ggc aaa gag atg gtg ttg atc tct gtc ggt ggc atc 816 Tyr Ala Arg Val Gly Lys Glu Met Val Leu Ile Ser Val Gly Gly Ile 260 265 270 agc acc cct gag caa gcc tgg gaa cgc atc acc tcc ggc gca acc ctt 864 Ser Thr Pro Glu Gln Ala Trp Glu Arg Ile Thr Ser Gly Ala Thr Leu 275 280 285 ctg cag gga tac acc cca ttc atc tac ggt ggc ccc gat tgg atc aga 912 Leu Gln Gly Tyr Thr Pro Phe Ile Tyr Gly Gly Pro Asp Trp Ile Arg 290 295 300 gat atc cac ctt ggt atc gcc aag cag ctg aaa gct cac ggt ctg cgc 960 Asp Ile His Leu Gly Ile Ala Lys Gln Leu Lys Ala His Gly Leu Arg 305 310 315 320 aac atc gct gac gct gtg ggc agc gaa ttg gag tgg aag aac 1002 Asn Ile Ala Asp Ala Val Gly Ser Glu Leu Glu Trp Lys Asn 325 330 taaacagacc aaacacacgt gcc 1025 <210> 980 <211> 334 <212> PRT <213> Corynebacterium glutamicum <400> 980 Leu Gly Val Val Asp Gly Val Ala Pro Leu Asn Arg Thr Met Glu Lys 1 5 10 15 Ile Ile Ala Val His Asp Asp Ser Leu Ser Gln Glu Val Phe Gly Val 20 25 30 Thr Phe Pro Arg Pro Leu Gly Leu Ala Ala Gly Phe Asp Lys Asn Ala 35 40 45 Ser Met Ala Asp Ala Trp Gly Ala Val Gly Phe Gly Tyr Ala Glu Leu 50 55 60 Gly Thr Val Thr Ala Phe Pro Gln Pro Gly Asn Pro Thr Pro Arg Leu 65 70 75 80 Phe Arg Leu Pro Ala Asp Lys Ala Ile Leu Asn Arg Met Gly Phe Asn 85 90 95 Asn Leu Gly Ala Ala Glu Val Ala Lys Asn Leu Arg Asn Arg Lys Ser 100 105 110 Thr Asp Val Ile Gly Ile Asn Ile Gly Lys Thr Lys Val Val Pro Ala 115 120 125 Glu His Ala Val Asp Asp Tyr Arg Arg Ser Ala Ser Leu Leu Gly Asp 130 135 140 Leu Ala Asp Tyr Leu Val Val Asn Val Ser Ser Pro Asn Thr Pro Gly 145 150 155 160 Leu Arg Asp Leu Gln Ala Val Glu Ser Leu Arg Pro Ile Leu Ala Ala 165 170 175 Val Gln Glu Ser Thr Thr Val Pro Val Leu Val Lys Ile Ala Pro Asp 180 185 190 Leu Ser Asp Glu Asp Ile Asp Ala Val Ala Asp Leu Ala Val Glu Leu 195 200 205 Lys Leu Ala Gly Ile Val Ala Thr Asn Thr Thr Ile Ser Arg Glu Gly 210 215 220 Leu Asn Thr Pro Ser Gly Glu Val Glu Ala Met Gly Ala Gly Gly Ile 225 230 235 240 Ser Gly Ala Pro Val Ala Ala Arg Ser Leu Glu Val Leu Lys Arg Leu 245 250 255 Tyr Ala Arg Val Gly Lys Glu Met Val Leu Ile Ser Val Gly Gly Ile 260 265 270 Ser Thr Pro Glu Gln Ala Trp Glu Arg Ile Thr Ser Gly Ala Thr Leu 275 280 285 Leu Gln Gly Tyr Thr Pro Phe Ile Tyr Gly Gly Pro Asp Trp Ile Arg 290 295 300 Asp Ile His Leu Gly Ile Ala Lys Gln Leu Lys Ala His Gly Leu Arg 305 310 315 320 Asn Ile Ala Asp Ala Val Gly Ser Glu Leu Glu Trp Lys Asn 325 330 <210> 981 <211> 675 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(652) <223> RXA01660 <400> 981 gaaaactggt gtttttcggc cgtgtccacc ccaggttcta tgctgtaaca aacgcgggtt 60 taaacctcaa tcatcaaatt agggaagggc tgggaaatcc atg tca tct aat tcc 115 Met Ser Ser Asn Ser 1 5 att aac gca gaa gcg cgc gct gag ctt gct gaa ctg atc aaa gag cta 163 Ile Asn Ala Glu Ala Arg Ala Glu Leu Ala Glu Leu Ile Lys Glu Leu 10 15 20 gct gtc gtc cac ggt gaa gtc acc ttg tct tcg ggc aag aag gct gat 211 Ala Val Val His Gly Glu Val Thr Leu Ser Ser Gly Lys Lys Ala Asp 25 30 35 tac tac atc gat gtc cgt cgt gcc acc ttg cac gcg cgc gca tct cgc 259 Tyr Tyr Ile Asp Val Arg Arg Ala Thr Leu His Ala Arg Ala Ser Arg 40 45 50 ctg atc ggt cag ctg ctg cgc gaa gcc acc gct gac tgg gac tat gac 307 Leu Ile Gly Gln Leu Leu Arg Glu Ala Thr Ala Asp Trp Asp Tyr Asp 55 60 65 gca gtt ggc ggc ctg acc ttg ggc gct gac ccg gtt gcc acc gcc atc 355 Ala Val Gly Gly Leu Thr Leu Gly Ala Asp Pro Val Ala Thr Ala Ile 70 75 80 85 atg cac gcc gac ggc cgc gat atc aac gcg ttt gtg gtg cgc aag gag 403 Met His Ala Asp Gly Arg Asp Ile Asn Ala Phe Val Val Arg Lys Glu 90 95 100 gcc aag aag cac ggc atg cag cgt cgc att gag ggc cct gac ctg acg 451 Ala Lys Lys His Gly Met Gln Arg Arg Ile Glu Gly Pro Asp Leu Thr 105 110 115 ggc aag aag gtg ctc gtg gtg gaa gat acc acc acc acc gga aat tcc 499 Gly Lys Lys Val Leu Val Val Glu Asp Thr Thr Thr Thr Gly Asn Ser 120 125 130 cct ctg aca gct gtt gcc gcg ttg cgt gaa gct ggc att gag gtt gtg 547 Pro Leu Thr Ala Val Ala Ala Leu Arg Glu Ala Gly Ile Glu Val Val 135 140 145 ggc gtt gcc acc gtg gtc gat cgc gca acc ggt gca gat gag gtt atc 595 Gly Val Ala Thr Val Val Asp Arg Ala Thr Gly Ala Asp Glu Val Ile 150 155 160 165 gca gcg gaa ggc ctt cct tac cgc agc ttg ctg gga ctt tct gat ctt 643 Ala Ala Glu Gly Leu Pro Tyr Arg Ser Leu Leu Gly Leu Ser Asp Leu 170 175 180 gga ctc aac taacaccccc ggccccacgg agt 675 Gly Leu Asn <210> 982 <211> 184 <212> PRT <213> Corynebacterium glutamicum <400> 982 Met Ser Ser Asn Ser Ile Asn Ala Glu Ala Arg Ala Glu Leu Ala Glu 1 5 10 15 Leu Ile Lys Glu Leu Ala Val Val His Gly Glu Val Thr Leu Ser Ser 20 25 30 Gly Lys Lys Ala Asp Tyr Tyr Ile Asp Val Arg Arg Ala Thr Leu His 35 40 45 Ala Arg Ala Ser Arg Leu Ile Gly Gln Leu Leu Arg Glu Ala Thr Ala 50 55 60 Asp Trp Asp Tyr Asp Ala Val Gly Gly Leu Thr Leu Gly Ala Asp Pro 65 70 75 80 Val Ala Thr Ala Ile Met His Ala Asp Gly Arg Asp Ile Asn Ala Phe 85 90 95 Val Val Arg Lys Glu Ala Lys Lys His Gly Met Gln Arg Arg Ile Glu 100 105 110 Gly Pro Asp Leu Thr Gly Lys Lys Val Leu Val Val Glu Asp Thr Thr 115 120 125 Thr Thr Gly Asn Ser Pro Leu Thr Ala Val Ala Ala Leu Arg Glu Ala 130 135 140 Gly Ile Glu Val Val Gly Val Ala Thr Val Val Asp Arg Ala Thr Gly 145 150 155 160 Ala Asp Glu Val Ile Ala Ala Glu Gly Leu Pro Tyr Arg Ser Leu Leu 165 170 175 Gly Leu Ser Asp Leu Gly Leu Asn 180 <210> 983 <211> 957 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(934) <223> RXA02235 <400> 983 gtgtcaccgc agctgtccag ggcatagagg ccctgcgtga gggcgttgtc agcgtccgcg 60 cgctgcagga actcgaccac gcagtcaagg cttaagccct atg aca ttc ggc gag 115 Met Thr Phe Gly Glu 1 5 aag ctt ctg aac gcc gcc tcc acc cgt ggc agg cta tgc gtg ggc att 163 Lys Leu Leu Asn Ala Ala Ser Thr Arg Gly Arg Leu Cys Val Gly Ile 10 15 20 gat ccc cac gaa agc ctg ctg acg tcc tgg ggg ctg ccg gta aac gta 211 Asp Pro His Glu Ser Leu Leu Thr Ser Trp Gly Leu Pro Val Asn Val 25 30 35 gac gga ctt gcg gag ttc tcc cgc gcc tgc gtg gag gct ttc gcc gac 259 Asp Gly Leu Ala Glu Phe Ser Arg Ala Cys Val Glu Ala Phe Ala Asp 40 45 50 acc gtg gca ttg gtg aag cct cag gtg gcg ttc tat gag cgt ttc ggt 307 Thr Val Ala Leu Val Lys Pro Gln Val Ala Phe Tyr Glu Arg Phe Gly 55 60 65 tcc gct ggc ttt gcc atc ttg gaa gaa acc att cag acg ctg cgt gag 355 Ser Ala Gly Phe Ala Ile Leu Glu Glu Thr Ile Gln Thr Leu Arg Glu 70 75 80 85 cgt ggc tgt ttg gtg gtc tct gac gcc aaa cgc ggc gat att ggc tcc 403 Arg Gly Cys Leu Val Val Ser Asp Ala Lys Arg Gly Asp Ile Gly Ser 90 95 100 acc atg gct ggc tat gcc tca gcg tgg tta gat cca gcg tca ccg ctg 451 Thr Met Ala Gly Tyr Ala Ser Ala Trp Leu Asp Pro Ala Ser Pro Leu 105 110 115 tct agc gac gct gtg acg gtc tct ccc tac ctt ggt ttt cat tcc ttg 499 Ser Ser Asp Ala Val Thr Val Ser Pro Tyr Leu Gly Phe His Ser Leu 120 125 130 gac cca gtg ttc gaa ctt gcc gag caa cac ggc agg gga gtg ttt gtc 547 Asp Pro Val Phe Glu Leu Ala Glu Gln His Gly Arg Gly Val Phe Val 135 140 145 ttg gcc gcg acc tca aac cct gag gcc cgc gaa ctc cag gac cag caa 595 Leu Ala Ala Thr Ser Asn Pro Glu Ala Arg Glu Leu Gln Asp Gln Gln 150 155 160 165 aac gct gac ggc gtg agc att tcc cag cag atc gtg gat cag gca gcg 643 Asn Ala Asp Gly Val Ser Ile Ser Gln Gln Ile Val Asp Gln Ala Ala 170 175 180 gcg ctt aac gcg cct tat atg gcc cag ggc aag gct ggc aac att ggc 691 Ala Leu Asn Ala Pro Tyr Met Ala Gln Gly Lys Ala Gly Asn Ile Gly 185 190 195 gtc gtc atc ggc gcc acc ttg tcc aaa cca cca cgc tta tcg acg ctc 739 Val Val Ile Gly Ala Thr Leu Ser Lys Pro Pro Arg Leu Ser Thr Leu 200 205 210 ggg ggc gcc att ttg atg ccc ggc gtc ggc gcc cag ggc ggc acg gca 787 Gly Gly Ala Ile Leu Met Pro Gly Val Gly Ala Gln Gly Gly Thr Ala 215 220 225 agc gac gtt gat gag att gcg gga gac atg gct cat ctt gca ttc cca 835 Ser Asp Val Asp Glu Ile Ala Gly Asp Met Ala His Leu Ala Phe Pro 230 235 240 245 aat gtc tct aga agt att ttg gcg aca ggc cca gat atc gct gaa atg 883 Asn Val Ser Arg Ser Ile Leu Ala Thr Gly Pro Asp Ile Ala Glu Met 250 255 260 aag aat tct gtg gca aaa aat gct gca gac ttt cct ggt ttc ccc agg 931 Lys Asn Ser Val Ala Lys Asn Ala Ala Asp Phe Pro Gly Phe Pro Arg 265 270 275 tca tagtcgcgga aacggccctt aat 957 Ser <210> 984 <211> 278 <212> PRT <213> Corynebacterium glutamicum <400> 984 Met Thr Phe Gly Glu Lys Leu Leu Asn Ala Ala Ser Thr Arg Gly Arg 1 5 10 15 Leu Cys Val Gly Ile Asp Pro His Glu Ser Leu Leu Thr Ser Trp Gly 20 25 30 Leu Pro Val Asn Val Asp Gly Leu Ala Glu Phe Ser Arg Ala Cys Val 35 40 45 Glu Ala Phe Ala Asp Thr Val Ala Leu Val Lys Pro Gln Val Ala Phe 50 55 60 Tyr Glu Arg Phe Gly Ser Ala Gly Phe Ala Ile Leu Glu Glu Thr Ile 65 70 75 80 Gln Thr Leu Arg Glu Arg Gly Cys Leu Val Val Ser Asp Ala Lys Arg 85 90 95 Gly Asp Ile Gly Ser Thr Met Ala Gly Tyr Ala Ser Ala Trp Leu Asp 100 105 110 Pro Ala Ser Pro Leu Ser Ser Asp Ala Val Thr Val Ser Pro Tyr Leu 115 120 125 Gly Phe His Ser Leu Asp Pro Val Phe Glu Leu Ala Glu Gln His Gly 130 135 140 Arg Gly Val Phe Val Leu Ala Ala Thr Ser Asn Pro Glu Ala Arg Glu 145 150 155 160 Leu Gln Asp Gln Gln Asn Ala Asp Gly Val Ser Ile Ser Gln Gln Ile 165 170 175 Val Asp Gln Ala Ala Ala Leu Asn Ala Pro Tyr Met Ala Gln Gly Lys 180 185 190 Ala Gly Asn Ile Gly Val Val Ile Gly Ala Thr Leu Ser Lys Pro Pro 195 200 205 Arg Leu Ser Thr Leu Gly Gly Ala Ile Leu Met Pro Gly Val Gly Ala 210 215 220 Gln Gly Gly Thr Ala Ser Asp Val Asp Glu Ile Ala Gly Asp Met Ala 225 230 235 240 His Leu Ala Phe Pro Asn Val Ser Arg Ser Ile Leu Ala Thr Gly Pro 245 250 255 Asp Ile Ala Glu Met Lys Asn Ser Val Ala Lys Asn Ala Ala Asp Phe 260 265 270 Pro Gly Phe Pro Arg Ser 275 <210> 985 <211> 852 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(829) <223> RXN01892 <400> 985 ggtctcagtg gcttcttggt tgctgtgatt ttttcaaggc gtaccccgtg gccgatgtta 60 aaagcggttg gcacaacccc tactgaagga gaacaccact gtg acc acc tcg agt 115 Val Thr Thr Ser Ser 1 5 gaa caa ccc cgt aca gga tac aag cga gtg atg tta aag ctc gga ggt 163 Glu Gln Pro Arg Thr Gly Tyr Lys Arg Val Met Leu Lys Leu Gly Gly 10 15 20 gaa atg ttt ggt ggt ggc aaa gtc ggc gtc gat cct gat gta gta gac 211 Glu Met Phe Gly Gly Gly Lys Val Gly Val Asp Pro Asp Val Val Asp 25 30 35 aat gtt gca cgt cag atc gct gaa gtt gct aaa act gga gca gag att 259 Asn Val Ala Arg Gln Ile Ala Glu Val Ala Lys Thr Gly Ala Glu Ile 40 45 50 gcc gtt gtt atc ggt ggc gga aac ttc ttc cgc gga gct gag ctt cag 307 Ala Val Val Ile Gly Gly Gly Asn Phe Phe Arg Gly Ala Glu Leu Gln 55 60 65 cag cgt ggc atg gac cgc gca cgg tcc gat tac atg ggt atg ctc ggc 355 Gln Arg Gly Met Asp Arg Ala Arg Ser Asp Tyr Met Gly Met Leu Gly 70 75 80 85 aca gtc atg aac tgc ctc gcc ttg cag gac ttc ctc ggt cag cat ggc 403 Thr Val Met Asn Cys Leu Ala Leu Gln Asp Phe Leu Gly Gln His Gly 90 95 100 gtt gaa tgc cgt gtc cag acc gcc atc aac atg gca cag gtc gca gaa 451 Val Glu Cys Arg Val Gln Thr Ala Ile Asn Met Ala Gln Val Ala Glu 105 110 115 cca tat ctg cca ctg cgc gca gaa cgc cac ctg gaa aag ggc cgc gtt 499 Pro Tyr Leu Pro Leu Arg Ala Glu Arg His Leu Glu Lys Gly Arg Val 120 125 130 gtc atc ttc ggt gct ggc atg ggt atg ccg tac ttt tcc acg gac acc 547 Val Ile Phe Gly Ala Gly Met Gly Met Pro Tyr Phe Ser Thr Asp Thr 135 140 145 act gct gca cag cgt gcg ttg gaa atc ggc tgt gac gtc cta ctg atg 595 Thr Ala Ala Gln Arg Ala Leu Glu Ile Gly Cys Asp Val Leu Leu Met 150 155 160 165 gct aag gct gtt gac ggt gtg tac agc gat gat cct cgt acc aac cca 643 Ala Lys Ala Val Asp Gly Val Tyr Ser Asp Asp Pro Arg Thr Asn Pro 170 175 180 gat gct gag ctc ttc acc gaa att act cca aag gaa gta att gag aag 691 Asp Ala Glu Leu Phe Thr Glu Ile Thr Pro Lys Glu Val Ile Glu Lys 185 190 195 ggc ctg aag gtt gcc gat gca act gca ttc agc ctc tgc atg gac aac 739 Gly Leu Lys Val Ala Asp Ala Thr Ala Phe Ser Leu Cys Met Asp Asn 200 205 210 aag atg cct atc ttg gtg ttt aac ctg ctt act gaa ggc aac att gct 787 Lys Met Pro Ile Leu Val Phe Asn Leu Leu Thr Glu Gly Asn Ile Ala 215 220 225 cgc gcc atc agc ggt gaa cgt atc ggt act ctg gtc gag tcc 829 Arg Ala Ile Ser Gly Glu Arg Ile Gly Thr Leu Val Glu Ser 230 235 240 tgatacattt agtcttataa aca 852 <210> 986 <211> 243 <212> PRT <213> Corynebacterium glutamicum <400> 986 Val Thr Thr Ser Ser Glu Gln Pro Arg Thr Gly Tyr Lys Arg Val Met 1 5 10 15 Leu Lys Leu Gly Gly Glu Met Phe Gly Gly Gly Lys Val Gly Val Asp 20 25 30 Pro Asp Val Val Asp Asn Val Ala Arg Gln Ile Ala Glu Val Ala Lys 35 40 45 Thr Gly Ala Glu Ile Ala Val Val Ile Gly Gly Gly Asn Phe Phe Arg 50 55 60 Gly Ala Glu Leu Gln Gln Arg Gly Met Asp Arg Ala Arg Ser Asp Tyr 65 70 75 80 Met Gly Met Leu Gly Thr Val Met Asn Cys Leu Ala Leu Gln Asp Phe 85 90 95 Leu Gly Gln His Gly Val Glu Cys Arg Val Gln Thr Ala Ile Asn Met 100 105 110 Ala Gln Val Ala Glu Pro Tyr Leu Pro Leu Arg Ala Glu Arg His Leu 115 120 125 Glu Lys Gly Arg Val Val Ile Phe Gly Ala Gly Met Gly Met Pro Tyr 130 135 140 Phe Ser Thr Asp Thr Thr Ala Ala Gln Arg Ala Leu Glu Ile Gly Cys 145 150 155 160 Asp Val Leu Leu Met Ala Lys Ala Val Asp Gly Val Tyr Ser Asp Asp 165 170 175 Pro Arg Thr Asn Pro Asp Ala Glu Leu Phe Thr Glu Ile Thr Pro Lys 180 185 190 Glu Val Ile Glu Lys Gly Leu Lys Val Ala Asp Ala Thr Ala Phe Ser 195 200 205 Leu Cys Met Asp Asn Lys Met Pro Ile Leu Val Phe Asn Leu Leu Thr 210 215 220 Glu Gly Asn Ile Ala Arg Ala Ile Ser Gly Glu Arg Ile Gly Thr Leu 225 230 235 240 Val Glu Ser <210> 987 <211> 798 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (47)..(775) <223> FRXA01892 <400> 987 atgttaaaag cggttggcac aacccctact gaaggagaac accacg gtg acc acc tcg 58 Val Thr Thr Ser 1 agt gaa caa ccc cgt aca gga tac aaa cga gtg atg tta aag ctc gaa 106 Ser Glu Gln Pro Arg Thr Gly Tyr Lys Arg Val Met Leu Lys Leu Glu 5 10 15 20 ggt gaa atg ttt ggt ggt ggc aaa gtc ggc gtc gat cct gat gta gta 154 Gly Glu Met Phe Gly Gly Gly Lys Val Gly Val Asp Pro Asp Val Val 25 30 35 gac aat gtt gca cgt cag atc gct gaa gtt gct aaa act gga gca gag 202 Asp Asn Val Ala Arg Gln Ile Ala Glu Val Ala Lys Thr Gly Ala Glu 40 45 50 att gcc gtt gtt atc ggt ggc gga aac ttc ttc cgc gga gct gag ctt 250 Ile Ala Val Val Ile Gly Gly Gly Asn Phe Phe Arg Gly Ala Glu Leu 55 60 65 cag cag cgt ggc atg gac cgc gca cgg tcc gat tac atg ggt atg ctc 298 Gln Gln Arg Gly Met Asp Arg Ala Arg Ser Asp Tyr Met Gly Met Leu 70 75 80 ggc aca gtc atg aac tgc ctc gcc ttg cag gac ttc ctc ggt cag cat 346 Gly Thr Val Met Asn Cys Leu Ala Leu Gln Asp Phe Leu Gly Gln His 85 90 95 100 ggc gtt gaa tgc cgt gtc cag acc gcc atc aac atg gca cag gtc gca 394 Gly Val Glu Cys Arg Val Gln Thr Ala Ile Asn Met Ala Gln Val Ala 105 110 115 gaa cca tat ctg cca ctg cgc gca gaa cgc cac ctg gaa aag ggc cgc 442 Glu Pro Tyr Leu Pro Leu Arg Ala Glu Arg His Leu Glu Lys Gly Arg 120 125 130 gtt gtc atc ttc ggt gct ggc atg ggt atg ccg tac ttt tcc acg gac 490 Val Val Ile Phe Gly Ala Gly Met Gly Met Pro Tyr Phe Ser Thr Asp 135 140 145 acc act gct gca cag cgt gcg ttg gaa atc ggc tgt gac gtc cta ctg 538 Thr Thr Ala Ala Gln Arg Ala Leu Glu Ile Gly Cys Asp Val Leu Leu 150 155 160 atg gct aag gct gtt gac ggt gtg tac agc gat gat cct cgt acc aac 586 Met Ala Lys Ala Val Asp Gly Val Tyr Ser Asp Asp Pro Arg Thr Asn 165 170 175 180 cca gat gct gag ctc ttc acc gaa att act cca aag gaa gta att gag 634 Pro Asp Ala Glu Leu Phe Thr Glu Ile Thr Pro Lys Glu Val Ile Glu 185 190 195 aag ggc ctg aag gtt gcc gat gca act gca ttc agc ctc tgc atg gac 682 Lys Gly Leu Lys Val Ala Asp Ala Thr Ala Phe Ser Leu Cys Met Asp 200 205 210 aac aag atg cct atc ttg gtg ttt aac ctg ctt act gaa ggc aac att 730 Asn Lys Met Pro Ile Leu Val Phe Asn Leu Leu Thr Glu Gly Asn Ile 215 220 225 gct cgc gcc atc agc ggt gaa cgt atc ggt act ctg gtc gag tcc 775 Ala Arg Ala Ile Ser Gly Glu Arg Ile Gly Thr Leu Val Glu Ser 230 235 240 tgatacattt agtcttataa aca 798 <210> 988 <211> 243 <212> PRT <213> Corynebacterium glutamicum <400> 988 Val Thr Thr Ser Ser Glu Gln Pro Arg Thr Gly Tyr Lys Arg Val Met 1 5 10 15 Leu Lys Leu Glu Gly Glu Met Phe Gly Gly Gly Lys Val Gly Val Asp 20 25 30 Pro Asp Val Val Asp Asn Val Ala Arg Gln Ile Ala Glu Val Ala Lys 35 40 45 Thr Gly Ala Glu Ile Ala Val Val Ile Gly Gly Gly Asn Phe Phe Arg 50 55 60 Gly Ala Glu Leu Gln Gln Arg Gly Met Asp Arg Ala Arg Ser Asp Tyr 65 70 75 80 Met Gly Met Leu Gly Thr Val Met Asn Cys Leu Ala Leu Gln Asp Phe 85 90 95 Leu Gly Gln His Gly Val Glu Cys Arg Val Gln Thr Ala Ile Asn Met 100 105 110 Ala Gln Val Ala Glu Pro Tyr Leu Pro Leu Arg Ala Glu Arg His Leu 115 120 125 Glu Lys Gly Arg Val Val Ile Phe Gly Ala Gly Met Gly Met Pro Tyr 130 135 140 Phe Ser Thr Asp Thr Thr Ala Ala Gln Arg Ala Leu Glu Ile Gly Cys 145 150 155 160 Asp Val Leu Leu Met Ala Lys Ala Val Asp Gly Val Tyr Ser Asp Asp 165 170 175 Pro Arg Thr Asn Pro Asp Ala Glu Leu Phe Thr Glu Ile Thr Pro Lys 180 185 190 Glu Val Ile Glu Lys Gly Leu Lys Val Ala Asp Ala Thr Ala Phe Ser 195 200 205 Leu Cys Met Asp Asn Lys Met Pro Ile Leu Val Phe Asn Leu Leu Thr 210 215 220 Glu Gly Asn Ile Ala Arg Ala Ile Ser Gly Glu Arg Ile Gly Thr Leu 225 230 235 240 Val Glu Ser <210> 989 <211> 798 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(775) <223> RXA00105 <400> 989 catcttgatc tgtcgccctg aacttgcaga tgaacttctc gagatgtgcg cgaagttcta 60 cgaggagaat ggaacttact aacgctgtta tgatgacggc atg act gtt cca acg 115 Met Thr Val Pro Thr 1 5 cct tat gaa gac ctt ctt cgg aag att gct gaa gaa ggg tcc cac aag 163 Pro Tyr Glu Asp Leu Leu Arg Lys Ile Ala Glu Glu Gly Ser His Lys 10 15 20 gac gac cgc acc ggc acc ggc act act tct tta ttc gga caa caa atc 211 Asp Asp Arg Thr Gly Thr Gly Thr Thr Ser Leu Phe Gly Gln Gln Ile 25 30 35 cgc ttt gat ctc aat gaa ggt ttt ccc ctt ctg acc acc aag aag gtc 259 Arg Phe Asp Leu Asn Glu Gly Phe Pro Leu Leu Thr Thr Lys Lys Val 40 45 50 cat ttc cac tct gtt gtg ggt gag ctt ttg tgg ttc ctt cag ggg gat 307 His Phe His Ser Val Val Gly Glu Leu Leu Trp Phe Leu Gln Gly Asp 55 60 65 tcc aac gtc aaa tgg ctg cag gat aac aac atc cgc att tgg aat gaa 355 Ser Asn Val Lys Trp Leu Gln Asp Asn Asn Ile Arg Ile Trp Asn Glu 70 75 80 85 tgg gca gat gag gac ggc gag ctg ggc cct gtt tat ggt gtc cag tgg 403 Trp Ala Asp Glu Asp Gly Glu Leu Gly Pro Val Tyr Gly Val Gln Trp 90 95 100 cgt tct tgg cca acc cct gat ggt cgt cac att gac cag atc tca ggt 451 Arg Ser Trp Pro Thr Pro Asp Gly Arg His Ile Asp Gln Ile Ser Gly 105 110 115 gct tta gaa act ctg cga aac aac cct gat tca cgt cgc aat att gtc 499 Ala Leu Glu Thr Leu Arg Asn Asn Pro Asp Ser Arg Arg Asn Ile Val 120 125 130 tcg gcg tgg aat gtt tcc gag ctt gaa aac atg gct ctt ccc cct tgt 547 Ser Ala Trp Asn Val Ser Glu Leu Glu Asn Met Ala Leu Pro Pro Cys 135 140 145 cac ttg ctt ttc cag ctc tat gtc gcc gat ggc aaa ctg tct tgc cag 595 His Leu Leu Phe Gln Leu Tyr Val Ala Asp Gly Lys Leu Ser Cys Gln 150 155 160 165 ctc tac cag cgt tct gcg gac atg ttc ctg ggt gtg cct ttc aac atc 643 Leu Tyr Gln Arg Ser Ala Asp Met Phe Leu Gly Val Pro Phe Asn Ile 170 175 180 gca tct tat gca ctg ctc acc cac atg ttt gcc cag cag gca ggc ttg 691 Ala Ser Tyr Ala Leu Leu Thr His Met Phe Ala Gln Gln Ala Gly Leu 185 190 195 gaa gtc ggc gag ttc att tgg act ggc ggc gac tgc cac att tat gac 739 Glu Val Gly Glu Phe Ile Trp Thr Gly Gly Asp Cys His Ile Tyr Asp 200 205 210 aac cac aag gaa cag gtc gcg gag cag ctg agc cga taagctcgcc 785 Asn His Lys Glu Gln Val Ala Glu Gln Leu Ser Arg 215 220 225 cctaccccac ctt 798 <210> 990 <211> 225 <212> PRT <213> Corynebacterium glutamicum <400> 990 Met Thr Val Pro Thr Pro Tyr Glu Asp Leu Leu Arg Lys Ile Ala Glu 1 5 10 15 Glu Gly Ser His Lys Asp Asp Arg Thr Gly Thr Gly Thr Thr Ser Leu 20 25 30 Phe Gly Gln Gln Ile Arg Phe Asp Leu Asn Glu Gly Phe Pro Leu Leu 35 40 45 Thr Thr Lys Lys Val His Phe His Ser Val Val Gly Glu Leu Leu Trp 50 55 60 Phe Leu Gln Gly Asp Ser Asn Val Lys Trp Leu Gln Asp Asn Asn Ile 65 70 75 80 Arg Ile Trp Asn Glu Trp Ala Asp Glu Asp Gly Glu Leu Gly Pro Val 85 90 95 Tyr Gly Val Gln Trp Arg Ser Trp Pro Thr Pro Asp Gly Arg His Ile 100 105 110 Asp Gln Ile Ser Gly Ala Leu Glu Thr Leu Arg Asn Asn Pro Asp Ser 115 120 125 Arg Arg Asn Ile Val Ser Ala Trp Asn Val Ser Glu Leu Glu Asn Met 130 135 140 Ala Leu Pro Pro Cys His Leu Leu Phe Gln Leu Tyr Val Ala Asp Gly 145 150 155 160 Lys Leu Ser Cys Gln Leu Tyr Gln Arg Ser Ala Asp Met Phe Leu Gly 165 170 175 Val Pro Phe Asn Ile Ala Ser Tyr Ala Leu Leu Thr His Met Phe Ala 180 185 190 Gln Gln Ala Gly Leu Glu Val Gly Glu Phe Ile Trp Thr Gly Gly Asp 195 200 205 Cys His Ile Tyr Asp Asn His Lys Glu Gln Val Ala Glu Gln Leu Ser 210 215 220 Arg 225 <210> 991 <211> 732 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(709) <223> RXA00131 <400> 991 aggctctcgg cggtcagctc accgaactga ccaaggagca ggctgagtac atcggcgttg 60 acgttgcagg cccattcaag ccggagcact accgctacta atg att gtc agc att 115 Met Ile Val Ser Ile 1 5 gag gga atc gac ggc gcc ggc aaa aac acc ctg gtt tcg gca tta acg 163 Glu Gly Ile Asp Gly Ala Gly Lys Asn Thr Leu Val Ser Ala Leu Thr 10 15 20 cag gtt att gat gca aaa gtc ctt gca ttc cca cgt tat gaa acc tcg 211 Gln Val Ile Asp Ala Lys Val Leu Ala Phe Pro Arg Tyr Glu Thr Ser 25 30 35 att cac gcc caa ttg gcc gcg gaa gca ctc cac ggc cgc atg ggc gac 259 Ile His Ala Gln Leu Ala Ala Glu Ala Leu His Gly Arg Met Gly Asp 40 45 50 ctc acc gac agc gcc tac gcc atg gcc acg ctt ttc gcc ctc gac cgc 307 Leu Thr Asp Ser Ala Tyr Ala Met Ala Thr Leu Phe Ala Leu Asp Arg 55 60 65 cac ttc gcg att gat gac tta aat gcg ccc ggc gtg gtg ctg ctc gac 355 His Phe Ala Ile Asp Asp Leu Asn Ala Pro Gly Val Val Leu Leu Asp 70 75 80 85 cga tac gtc gcc tcc aac gcg gct tat acc gcc gcc aga ttg ctt gac 403 Arg Tyr Val Ala Ser Asn Ala Ala Tyr Thr Ala Ala Arg Leu Leu Asp 90 95 100 gac gac gcc ccc cgc tgg gtt gcc gac ctg gaa ttc ggg cgg ctt ggg 451 Asp Asp Ala Pro Arg Trp Val Ala Asp Leu Glu Phe Gly Arg Leu Gly 105 110 115 ctc cca cgt ccg acg ctt caa gtg ttg ttg gat acc ccc gcg gag gta 499 Leu Pro Arg Pro Thr Leu Gln Val Leu Leu Asp Thr Pro Ala Glu Val 120 125 130 gcg caa gat agg gct aga cgt cga gaa gcg ctt gac tcc gcg cgt gcg 547 Ala Gln Asp Arg Ala Arg Arg Arg Glu Ala Leu Asp Ser Ala Arg Ala 135 140 145 cgg gac cgc tat gaa tcg gat tcg gcg ctg cag caa cgc acc gcc gag 595 Arg Asp Arg Tyr Glu Ser Asp Ser Ala Leu Gln Gln Arg Thr Ala Glu 150 155 160 165 cac tat cgc cgc ctc gcg gcg gac aac tgg gaa tca ccg tgg atc gtg 643 His Tyr Arg Arg Leu Ala Ala Asp Asn Trp Glu Ser Pro Trp Ile Val 170 175 180 gtt gcc cct gat gaa gac ccc ggc cac gtt gcg cag aga atc gtg gaa 691 Val Ala Pro Asp Glu Asp Pro Gly His Val Ala Gln Arg Ile Val Glu 185 190 195 ttc ctg ggt act ata aac taatcccaat tagcaggaag gat 732 Phe Leu Gly Thr Ile Asn 200 <210> 992 <211> 203 <212> PRT <213> Corynebacterium glutamicum <400> 992 Met Ile Val Ser Ile Glu Gly Ile Asp Gly Ala Gly Lys Asn Thr Leu 1 5 10 15 Val Ser Ala Leu Thr Gln Val Ile Asp Ala Lys Val Leu Ala Phe Pro 20 25 30 Arg Tyr Glu Thr Ser Ile His Ala Gln Leu Ala Ala Glu Ala Leu His 35 40 45 Gly Arg Met Gly Asp Leu Thr Asp Ser Ala Tyr Ala Met Ala Thr Leu 50 55 60 Phe Ala Leu Asp Arg His Phe Ala Ile Asp Asp Leu Asn Ala Pro Gly 65 70 75 80 Val Val Leu Leu Asp Arg Tyr Val Ala Ser Asn Ala Ala Tyr Thr Ala 85 90 95 Ala Arg Leu Leu Asp Asp Asp Ala Pro Arg Trp Val Ala Asp Leu Glu 100 105 110 Phe Gly Arg Leu Gly Leu Pro Arg Pro Thr Leu Gln Val Leu Leu Asp 115 120 125 Thr Pro Ala Glu Val Ala Gln Asp Arg Ala Arg Arg Arg Glu Ala Leu 130 135 140 Asp Ser Ala Arg Ala Arg Asp Arg Tyr Glu Ser Asp Ser Ala Leu Gln 145 150 155 160 Gln Arg Thr Ala Glu His Tyr Arg Arg Leu Ala Ala Asp Asn Trp Glu 165 170 175 Ser Pro Trp Ile Val Val Ala Pro Asp Glu Asp Pro Gly His Val Ala 180 185 190 Gln Arg Ile Val Glu Phe Leu Gly Thr Ile Asn 195 200 <210> 993 <211> 531 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(508) <223> RXA00266 <400> 993 agtaggggat cgtccagcga agcggtcgca gaggctgtga ggaagctcta agtcgactta 60 agtgcgcgaa gcagaccacc attaggtaga atcacccaac atg act gaa cgt act 115 Met Thr Glu Arg Thr 1 5 ctc atc ctt atc aag cca gac ggt gtt acc aac gga cac gtc ggc gaa 163 Leu Ile Leu Ile Lys Pro Asp Gly Val Thr Asn Gly His Val Gly Glu 10 15 20 atc atc gca cgt att gag cgc aag ggc ctg aag ctc gct gct ctg gat 211 Ile Ile Ala Arg Ile Glu Arg Lys Gly Leu Lys Leu Ala Ala Leu Asp 25 30 35 ctg cgt gtt gca gac cgc gag acc gct gaa aag cac tac gaa gag cac 259 Leu Arg Val Ala Asp Arg Glu Thr Ala Glu Lys His Tyr Glu Glu His 40 45 50 gct gac aag cca ttc ttc ggt gag ctc gtt gaa ttc atc acc tct gca 307 Ala Asp Lys Pro Phe Phe Gly Glu Leu Val Glu Phe Ile Thr Ser Ala 55 60 65 cct ctg atc gca ggc atc gtc gaa ggc gag cgt gca atc gat gca tgg 355 Pro Leu Ile Ala Gly Ile Val Glu Gly Glu Arg Ala Ile Asp Ala Trp 70 75 80 85 cgt cag ctt gct ggt ggc acc gac cca gtt gct aag gca acc cca ggc 403 Arg Gln Leu Ala Gly Gly Thr Asp Pro Val Ala Lys Ala Thr Pro Gly 90 95 100 acc atc cgc ggc gat ttc gca ctg act gtt gga gag aac gtt gtt cac 451 Thr Ile Arg Gly Asp Phe Ala Leu Thr Val Gly Glu Asn Val Val His 105 110 115 ggt tct gat tcc cca gag tcc gct gag cgc gag atc tcc atc tgg ttc 499 Gly Ser Asp Ser Pro Glu Ser Ala Glu Arg Glu Ile Ser Ile Trp Phe 120 125 130 cct aac ctg taatttttac ggttagaaaa aaa 531 Pro Asn Leu 135 <210> 994 <211> 136 <212> PRT <213> Corynebacterium glutamicum <400> 994 Met Thr Glu Arg Thr Leu Ile Leu Ile Lys Pro Asp Gly Val Thr Asn 1 5 10 15 Gly His Val Gly Glu Ile Ile Ala Arg Ile Glu Arg Lys Gly Leu Lys 20 25 30 Leu Ala Ala Leu Asp Leu Arg Val Ala Asp Arg Glu Thr Ala Glu Lys 35 40 45 His Tyr Glu Glu His Ala Asp Lys Pro Phe Phe Gly Glu Leu Val Glu 50 55 60 Phe Ile Thr Ser Ala Pro Leu Ile Ala Gly Ile Val Glu Gly Glu Arg 65 70 75 80 Ala Ile Asp Ala Trp Arg Gln Leu Ala Gly Gly Thr Asp Pro Val Ala 85 90 95 Lys Ala Thr Pro Gly Thr Ile Arg Gly Asp Phe Ala Leu Thr Val Gly 100 105 110 Glu Asn Val Val His Gly Ser Asp Ser Pro Glu Ser Ala Glu Arg Glu 115 120 125 Ile Ser Ile Trp Phe Pro Asn Leu 130 135 <210> 995 <211> 831 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(808) <223> RXA00718 <400> 995 gcaccaagct gcacaccgtt cagcttggtg atcagaagcc aggttccctt cgtgcactga 60 actcctctga gctgaccagc ttatacaagg tggtccaact gtg acg gaa att tcc 115 Val Thr Glu Ile Ser 1 5 aac atg cct gcc ggt ggc ctc atc gta gcc atc gac ggg ccg tct ggc 163 Asn Met Pro Ala Gly Gly Leu Ile Val Ala Ile Asp Gly Pro Ser Gly 10 15 20 acc gga aaa tcc acc aca tcc cgc gcg ctc gca acc cgt ctc tcg gcc 211 Thr Gly Lys Ser Thr Thr Ser Arg Ala Leu Ala Thr Arg Leu Ser Ala 25 30 35 aag tac cta gat act ggt gcg atg tac cgc gtc gca acg ctt cat gtg 259 Lys Tyr Leu Asp Thr Gly Ala Met Tyr Arg Val Ala Thr Leu His Val 40 45 50 ctt aac cag ggg att gac cct gca gat agc gca gcc gtg atc gct gca 307 Leu Asn Gln Gly Ile Asp Pro Ala Asp Ser Ala Ala Val Ile Ala Ala 55 60 65 acc gct gta ttg ccg ttg tcg att tct gac gat ccc gcc tcc act gag 355 Thr Ala Val Leu Pro Leu Ser Ile Ser Asp Asp Pro Ala Ser Thr Glu 70 75 80 85 gtg ttg ctc gcg ggc gtc gat gtg caa aag gac atc cgc gga cca gaa 403 Val Leu Leu Ala Gly Val Asp Val Gln Lys Asp Ile Arg Gly Pro Glu 90 95 100 gtc acc caa aat gtc tcc gca gtg tcc gcg atc cct gag gtt cgt gaa 451 Val Thr Gln Asn Val Ser Ala Val Ser Ala Ile Pro Glu Val Arg Glu 105 110 115 aac ttg gtg gcg ttg cag cgc gca ctc gcc gcc aaa gca cat cgc tgc 499 Asn Leu Val Ala Leu Gln Arg Ala Leu Ala Ala Lys Ala His Arg Cys 120 125 130 gtc gtc gaa ggc aga gac atc gga acg gca gtg ctt gtc gac gcg ccc 547 Val Val Glu Gly Arg Asp Ile Gly Thr Ala Val Leu Val Asp Ala Pro 135 140 145 atc aag gcg ttt ctc acc gcc tca gcg gaa gtc cgc gcc cag cga cgc 595 Ile Lys Ala Phe Leu Thr Ala Ser Ala Glu Val Arg Ala Gln Arg Arg 150 155 160 165 ttt gac caa gac acc gca gca ggt cgc gac gta gat ttc gac gct gtg 643 Phe Asp Gln Asp Thr Ala Ala Gly Arg Asp Val Asp Phe Asp Ala Val 170 175 180 ctg gca gat gtt gtt cgc cgc gat gaa cta gat tcc acc cgt gcc gcc 691 Leu Ala Asp Val Val Arg Arg Asp Glu Leu Asp Ser Thr Arg Ala Ala 185 190 195 tca ccg ctg aaa cca gca gat gat gca cac atc gtg gac acc tct gat 739 Ser Pro Leu Lys Pro Ala Asp Asp Ala His Ile Val Asp Thr Ser Asp 200 205 210 atg acc atg gat caa gta ctt gat cac ctc atc cac cta gtg gaa gcc 787 Met Thr Met Asp Gln Val Leu Asp His Leu Ile His Leu Val Glu Ala 215 220 225 tcc gct gaa agg agc aac cag tgactgataa acacaccatg cct 831 Ser Ala Glu Arg Ser Asn Gln 230 235 <210> 996 <211> 236 <212> PRT <213> Corynebacterium glutamicum <400> 996 Val Thr Glu Ile Ser Asn Met Pro Ala Gly Gly Leu Ile Val Ala Ile 1 5 10 15 Asp Gly Pro Ser Gly Thr Gly Lys Ser Thr Thr Ser Arg Ala Leu Ala 20 25 30 Thr Arg Leu Ser Ala Lys Tyr Leu Asp Thr Gly Ala Met Tyr Arg Val 35 40 45 Ala Thr Leu His Val Leu Asn Gln Gly Ile Asp Pro Ala Asp Ser Ala 50 55 60 Ala Val Ile Ala Ala Thr Ala Val Leu Pro Leu Ser Ile Ser Asp Asp 65 70 75 80 Pro Ala Ser Thr Glu Val Leu Leu Ala Gly Val Asp Val Gln Lys Asp 85 90 95 Ile Arg Gly Pro Glu Val Thr Gln Asn Val Ser Ala Val Ser Ala Ile 100 105 110 Pro Glu Val Arg Glu Asn Leu Val Ala Leu Gln Arg Ala Leu Ala Ala 115 120 125 Lys Ala His Arg Cys Val Val Glu Gly Arg Asp Ile Gly Thr Ala Val 130 135 140 Leu Val Asp Ala Pro Ile Lys Ala Phe Leu Thr Ala Ser Ala Glu Val 145 150 155 160 Arg Ala Gln Arg Arg Phe Asp Gln Asp Thr Ala Ala Gly Arg Asp Val 165 170 175 Asp Phe Asp Ala Val Leu Ala Asp Val Val Arg Arg Asp Glu Leu Asp 180 185 190 Ser Thr Arg Ala Ala Ser Pro Leu Lys Pro Ala Asp Asp Ala His Ile 195 200 205 Val Asp Thr Ser Asp Met Thr Met Asp Gln Val Leu Asp His Leu Ile 210 215 220 His Leu Val Glu Ala Ser Ala Glu Arg Ser Asn Gln 225 230 235 <210> 997 <211> 1785 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1762) <223> RXA01599 <400> 997 caccgaacgt ttaagttttc cgcaccgcct gactcgaaaa gatctttttt aaagagctgt 60 tcgatgttta ggttcaacca ggaaggtcgt ctcagacatc atg acc tct agt cga 115 Met Thr Ser Ser Arg 1 5 aaa gtc cgt ccc acc aaa cac att ttc gtc acc ggt gga gtt gtt tcc 163 Lys Val Arg Pro Thr Lys His Ile Phe Val Thr Gly Gly Val Val Ser 10 15 20 tca ctc ggc aaa ggc ctg acc gca gca agc ctt ggt caa ttg ctg att 211 Ser Leu Gly Lys Gly Leu Thr Ala Ala Ser Leu Gly Gln Leu Leu Ile 25 30 35 gca cgg gga ctg tcg gtg acc atg cag aag ctg gat cca tac ctc aat 259 Ala Arg Gly Leu Ser Val Thr Met Gln Lys Leu Asp Pro Tyr Leu Asn 40 45 50 gtt gat ccg ggc acc atg aat cct ttt gaa cac ggt gaa gtc ttt gtc 307 Val Asp Pro Gly Thr Met Asn Pro Phe Glu His Gly Glu Val Phe Val 55 60 65 acc gaa gac ggg gca gaa aca gac ctg gat ttg ggc cac tac gag cgt 355 Thr Glu Asp Gly Ala Glu Thr Asp Leu Asp Leu Gly His Tyr Glu Arg 70 75 80 85 ttc ctc gat cgc aac ctg ggg ctc aac gcc aat gtc acc acc ggc aag 403 Phe Leu Asp Arg Asn Leu Gly Leu Asn Ala Asn Val Thr Thr Gly Lys 90 95 100 gtg tat tcc act gtg atc gcc aag gag cgc agg gga gag tac ctg ggt 451 Val Tyr Ser Thr Val Ile Ala Lys Glu Arg Arg Gly Glu Tyr Leu Gly 105 110 115 aaa act gtg cag gtc atc cca cac atc act gat gag atc aaa gct cgt 499 Lys Thr Val Gln Val Ile Pro His Ile Thr Asp Glu Ile Lys Ala Arg 120 125 130 att ttg agc atg ggc gaa cca gat gct cat ggt aac gcc cca gac gtg 547 Ile Leu Ser Met Gly Glu Pro Asp Ala His Gly Asn Ala Pro Asp Val 135 140 145 gtg atc tct gag gtc ggt ggc acc gtc ggt gac att gaa tcc cag cca 595 Val Ile Ser Glu Val Gly Gly Thr Val Gly Asp Ile Glu Ser Gln Pro 150 155 160 165 ttc ctt gaa gca gct cgc cag gta cgc cat gaa att ggt cgt gaa aac 643 Phe Leu Glu Ala Ala Arg Gln Val Arg His Glu Ile Gly Arg Glu Asn 170 175 180 tgc ttc ttc atc cac tgt tct ttg gtg cca tac ttg gct acc tca ggt 691 Cys Phe Phe Ile His Cys Ser Leu Val Pro Tyr Leu Ala Thr Ser Gly 185 190 195 gag ctg aag acc aaa ccc acc cag cat tct gtc gca gag ctg cgc ggc 739 Glu Leu Lys Thr Lys Pro Thr Gln His Ser Val Ala Glu Leu Arg Gly 200 205 210 atc ggt att ttg ccg gat gct ctc gtg ctt cgt tgc gat cgg gag gtc 787 Ile Gly Ile Leu Pro Asp Ala Leu Val Leu Arg Cys Asp Arg Glu Val 215 220 225 cct caa ggt ctg aaa gat aag atc gcg atg atg tgc gat gtt gat tat 835 Pro Gln Gly Leu Lys Asp Lys Ile Ala Met Met Cys Asp Val Asp Tyr 230 235 240 245 gaa ggc gtt gta tct tgc cct gat tcc agt tct att tac aac att cca 883 Glu Gly Val Val Ser Cys Pro Asp Ser Ser Ser Ile Tyr Asn Ile Pro 250 255 260 gat gtc ctc tac cgc gag cac ctg gac acc ttc att att cgt cgc ctg 931 Asp Val Leu Tyr Arg Glu His Leu Asp Thr Phe Ile Ile Arg Arg Leu 265 270 275 ggc ctt ccg ttc cgt gat gtt gac tgg agc acc tgg cac gat ctg ctg 979 Gly Leu Pro Phe Arg Asp Val Asp Trp Ser Thr Trp His Asp Leu Leu 280 285 290 gaa cgg gtg aac aac cca cgc cat gag ctc acc gtc ggc atc gtg ggc 1027 Glu Arg Val Asn Asn Pro Arg His Glu Leu Thr Val Gly Ile Val Gly 295 300 305 aag tac att gat ctt ccc gat gct tat ctc tca gtg gtg gaa gct gtt 1075 Lys Tyr Ile Asp Leu Pro Asp Ala Tyr Leu Ser Val Val Glu Ala Val 310 315 320 325 cgc gct gca ggc tac gcc aat tgg acg cgc acc aat atc aag tgg att 1123 Arg Ala Ala Gly Tyr Ala Asn Trp Thr Arg Thr Asn Ile Lys Trp Ile 330 335 340 acc tca gat gat tgc gaa acc cca tct ggc gcc atg aaa gcg ctc agc 1171 Thr Ser Asp Asp Cys Glu Thr Pro Ser Gly Ala Met Lys Ala Leu Ser 345 350 355 ggt ttg gat gcc atc gtg gtt ccc gga ggt ttc ggt atc cga ggt atc 1219 Gly Leu Asp Ala Ile Val Val Pro Gly Gly Phe Gly Ile Arg Gly Ile 360 365 370 gaa ggc aaa atc ggt gcg att acg ttt gca cgt gag cac aag atc ccg 1267 Glu Gly Lys Ile Gly Ala Ile Thr Phe Ala Arg Glu His Lys Ile Pro 375 380 385 ctt ctt ggc cta tgc ctt ggc ctg cag tgc acc gtc atc gag gca gca 1315 Leu Leu Gly Leu Cys Leu Gly Leu Gln Cys Thr Val Ile Glu Ala Ala 390 395 400 405 cgc cag gca gga ctg gag cag gca tca tcc act gag ttt gac cca gct 1363 Arg Gln Ala Gly Leu Glu Gln Ala Ser Ser Thr Glu Phe Asp Pro Ala 410 415 420 gca acg cag cca gtg atc gcc acc atg gaa gag cag aaa gct gct gtg 1411 Ala Thr Gln Pro Val Ile Ala Thr Met Glu Glu Gln Lys Ala Ala Val 425 430 435 tcg ggt gaa gct gat ctg ggt ggc acc atg cgt ctt ggc gca tat cct 1459 Ser Gly Glu Ala Asp Leu Gly Gly Thr Met Arg Leu Gly Ala Tyr Pro 440 445 450 gca acc ctg gag gaa ggc tcc tta gta gcg gaa ctg tat ggc aca acg 1507 Ala Thr Leu Glu Glu Gly Ser Leu Val Ala Glu Leu Tyr Gly Thr Thr 455 460 465 gaa gtc tcc gag cgc cac cgt cac cgc tat gag gtc aat aat gcc tac 1555 Glu Val Ser Glu Arg His Arg His Arg Tyr Glu Val Asn Asn Ala Tyr 470 475 480 485 cgc gcc cag att gct gaa ggt tca gat ttg gtc ttc tcc gga acc tca 1603 Arg Ala Gln Ile Ala Glu Gly Ser Asp Leu Val Phe Ser Gly Thr Ser 490 495 500 cct gat gga cat ttg gtg gag ttc gtg gag tac ccc aaa gag gtg cat 1651 Pro Asp Gly His Leu Val Glu Phe Val Glu Tyr Pro Lys Glu Val His 505 510 515 cct tat ctg gtg gca acc cag gcg cac cct gag tac aaa tct cgt cca 1699 Pro Tyr Leu Val Ala Thr Gln Ala His Pro Glu Tyr Lys Ser Arg Pro 520 525 530 acc cat gct cat cca ctg ttt tac ggc ctg gtg aag acc gct ttg gag 1747 Thr His Ala His Pro Leu Phe Tyr Gly Leu Val Lys Thr Ala Leu Glu 535 540 545 ctg cgt gtc cac cct tagatctaca atgtgatcat ggt 1785 Leu Arg Val His Pro 550 <210> 998 <211> 554 <212> PRT <213> Corynebacterium glutamicum <400> 998 Met Thr Ser Ser Arg Lys Val Arg Pro Thr Lys His Ile Phe Val Thr 1 5 10 15 Gly Gly Val Val Ser Ser Leu Gly Lys Gly Leu Thr Ala Ala Ser Leu 20 25 30 Gly Gln Leu Leu Ile Ala Arg Gly Leu Ser Val Thr Met Gln Lys Leu 35 40 45 Asp Pro Tyr Leu Asn Val Asp Pro Gly Thr Met Asn Pro Phe Glu His 50 55 60 Gly Glu Val Phe Val Thr Glu Asp Gly Ala Glu Thr Asp Leu Asp Leu 65 70 75 80 Gly His Tyr Glu Arg Phe Leu Asp Arg Asn Leu Gly Leu Asn Ala Asn 85 90 95 Val Thr Thr Gly Lys Val Tyr Ser Thr Val Ile Ala Lys Glu Arg Arg 100 105 110 Gly Glu Tyr Leu Gly Lys Thr Val Gln Val Ile Pro His Ile Thr Asp 115 120 125 Glu Ile Lys Ala Arg Ile Leu Ser Met Gly Glu Pro Asp Ala His Gly 130 135 140 Asn Ala Pro Asp Val Val Ile Ser Glu Val Gly Gly Thr Val Gly Asp 145 150 155 160 Ile Glu Ser Gln Pro Phe Leu Glu Ala Ala Arg Gln Val Arg His Glu 165 170 175 Ile Gly Arg Glu Asn Cys Phe Phe Ile His Cys Ser Leu Val Pro Tyr 180 185 190 Leu Ala Thr Ser Gly Glu Leu Lys Thr Lys Pro Thr Gln His Ser Val 195 200 205 Ala Glu Leu Arg Gly Ile Gly Ile Leu Pro Asp Ala Leu Val Leu Arg 210 215 220 Cys Asp Arg Glu Val Pro Gln Gly Leu Lys Asp Lys Ile Ala Met Met 225 230 235 240 Cys Asp Val Asp Tyr Glu Gly Val Val Ser Cys Pro Asp Ser Ser Ser 245 250 255 Ile Tyr Asn Ile Pro Asp Val Leu Tyr Arg Glu His Leu Asp Thr Phe 260 265 270 Ile Ile Arg Arg Leu Gly Leu Pro Phe Arg Asp Val Asp Trp Ser Thr 275 280 285 Trp His Asp Leu Leu Glu Arg Val Asn Asn Pro Arg His Glu Leu Thr 290 295 300 Val Gly Ile Val Gly Lys Tyr Ile Asp Leu Pro Asp Ala Tyr Leu Ser 305 310 315 320 Val Val Glu Ala Val Arg Ala Ala Gly Tyr Ala Asn Trp Thr Arg Thr 325 330 335 Asn Ile Lys Trp Ile Thr Ser Asp Asp Cys Glu Thr Pro Ser Gly Ala 340 345 350 Met Lys Ala Leu Ser Gly Leu Asp Ala Ile Val Val Pro Gly Gly Phe 355 360 365 Gly Ile Arg Gly Ile Glu Gly Lys Ile Gly Ala Ile Thr Phe Ala Arg 370 375 380 Glu His Lys Ile Pro Leu Leu Gly Leu Cys Leu Gly Leu Gln Cys Thr 385 390 395 400 Val Ile Glu Ala Ala Arg Gln Ala Gly Leu Glu Gln Ala Ser Ser Thr 405 410 415 Glu Phe Asp Pro Ala Ala Thr Gln Pro Val Ile Ala Thr Met Glu Glu 420 425 430 Gln Lys Ala Ala Val Ser Gly Glu Ala Asp Leu Gly Gly Thr Met Arg 435 440 445 Leu Gly Ala Tyr Pro Ala Thr Leu Glu Glu Gly Ser Leu Val Ala Glu 450 455 460 Leu Tyr Gly Thr Thr Glu Val Ser Glu Arg His Arg His Arg Tyr Glu 465 470 475 480 Val Asn Asn Ala Tyr Arg Ala Gln Ile Ala Glu Gly Ser Asp Leu Val 485 490 495 Phe Ser Gly Thr Ser Pro Asp Gly His Leu Val Glu Phe Val Glu Tyr 500 505 510 Pro Lys Glu Val His Pro Tyr Leu Val Ala Thr Gln Ala His Pro Glu 515 520 525 Tyr Lys Ser Arg Pro Thr His Ala His Pro Leu Phe Tyr Gly Leu Val 530 535 540 Lys Thr Ala Leu Glu Leu Arg Val His Pro 545 550 <210> 999 <211> 3462 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(3439) <223> RXN02234 <400> 999 acccagaggc cgctgccggc ccaaatgatg caagccccct gtttgaccag tttgttgagc 60 tgatggatgc agacgctcag aagaaaggcg cataaataac atg cca aag cgt tca 115 Met Pro Lys Arg Ser 1 5 gat att aac cac gtc ctc gtc atc ggt tcc ggc ccc atc gtc att ggc 163 Asp Ile Asn His Val Leu Val Ile Gly Ser Gly Pro Ile Val Ile Gly 10 15 20 cag gca tgt gaa ttc gac tac tcc ggc acc cag gct tgc cgc gtg ctg 211 Gln Ala Cys Glu Phe Asp Tyr Ser Gly Thr Gln Ala Cys Arg Val Leu 25 30 35 aag gaa gag gga ctg cgc gtc acc ctc atc aac tcc aac cca gca acg 259 Lys Glu Glu Gly Leu Arg Val Thr Leu Ile Asn Ser Asn Pro Ala Thr 40 45 50 atc atg acc gac cca gaa atg gct gac cac acc tac gtg gag cca atc 307 Ile Met Thr Asp Pro Glu Met Ala Asp His Thr Tyr Val Glu Pro Ile 55 60 65 gag ccg gaa tac atc gac aag att ttc gct aag gaa atc gag cag ggc 355 Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala Lys Glu Ile Glu Gln Gly 70 75 80 85 cac cca atc gac gcc gtc ctg gca acc ctt ggt ggc cag act gca ctt 403 His Pro Ile Asp Ala Val Leu Ala Thr Leu Gly Gly Gln Thr Ala Leu 90 95 100 aac gca gct atc cag ctg gat cgc ctc ggc atc ctg gaa aag tac ggc 451 Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly Ile Leu Glu Lys Tyr Gly 105 110 115 gtt gaa ctc atc ggt gca gac atc gat gcc att gag cgc ggc gaa gat 499 Val Glu Leu Ile Gly Ala Asp Ile Asp Ala Ile Glu Arg Gly Glu Asp 120 125 130 cgc cag aag ttc aag gat att gtc acc acc atc ggt ggc gaa tcc gcg 547 Arg Gln Lys Phe Lys Asp Ile Val Thr Thr Ile Gly Gly Glu Ser Ala 135 140 145 cgt tcc cgc gtc tgc cac aac atg gaa gaa gtc cac gag act gtc gca 595 Arg Ser Arg Val Cys His Asn Met Glu Glu Val His Glu Thr Val Ala 150 155 160 165 gaa ctc ggc ctt cca gta gtc gtg cgt cca tcc ttc act atg ggt ggc 643 Glu Leu Gly Leu Pro Val Val Val Arg Pro Ser Phe Thr Met Gly Gly 170 175 180 ctg ggc tcc ggt ctt gca tac aac acc gaa gac ctt gag cgc atc gct 691 Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu Asp Leu Glu Arg Ile Ala 185 190 195 ggt ggc gga ctt gct gca tct cct gaa gca aac gtc ttg atc gaa gaa 739 Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala Asn Val Leu Ile Glu Glu 200 205 210 tcc atc ctt ggt tgg aag gaa ttc gag ctc gag ctc atg cgc gat acc 787 Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu Glu Leu Met Arg Asp Thr 215 220 225 gca gac aac gtt gtg gtt atc tgc tcc att gaa aac gtc gac gca ctg 835 Ala Asp Asn Val Val Val Ile Cys Ser Ile Glu Asn Val Asp Ala Leu 230 235 240 245 ggc gtg cac acc ggc gac tct gtc acc gtg gca cct gcc ctg acc ctg 883 Gly Val His Thr Gly Asp Ser Val Thr Val Ala Pro Ala Leu Thr Leu 250 255 260 act gac cgt gaa ttc cag aag atg cgc gat cag ggt atc gcc atc atc 931 Thr Asp Arg Glu Phe Gln Lys Met Arg Asp Gln Gly Ile Ala Ile Ile 265 270 275 cgc gag gtc ggc gtg gac acc ggt gga tgt aac atc cag ttc gcc atc 979 Arg Glu Val Gly Val Asp Thr Gly Gly Cys Asn Ile Gln Phe Ala Ile 280 285 290 aac cca gtt gat ggc cgc atc atc acc att gag atg aac cca cgt gtg 1027 Asn Pro Val Asp Gly Arg Ile Ile Thr Ile Glu Met Asn Pro Arg Val 295 300 305 tct cgt tcc tcc gct ctg gca tcc aag gca acg ggc ttc cca att gcc 1075 Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala Thr Gly Phe Pro Ile Ala 310 315 320 325 aag atg gct gcc aag ctg gct atc gga tac acc ctg gat gag atc acc 1123 Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr Thr Leu Asp Glu Ile Thr 330 335 340 aac gac atc act ggt gaa acc cca gct gcg ttt gag ccc acc atc gac 1171 Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala Phe Glu Pro Thr Ile Asp 345 350 355 tac gtc gtg gtc aag gcc cca cgc ttt gct ttc gag aag ttt gtc ggc 1219 Tyr Val Val Val Lys Ala Pro Arg Phe Ala Phe Glu Lys Phe Val Gly 360 365 370 gct gat gac act ttg acc acc acc atg aag tcc gtc ggt gag gtc atg 1267 Ala Asp Asp Thr Leu Thr Thr Thr Met Lys Ser Val Gly Glu Val Met 375 380 385 tcc ctg ggc cgc aac tac att gca gca ctg aac aag gca ctg cgt tcc 1315 Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu Asn Lys Ala Leu Arg Ser 390 395 400 405 ctg gaa acc aag cag cag ggt ttc tgg acc aag cct gat gag ttc ttc 1363 Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr Lys Pro Asp Glu Phe Phe 410 415 420 gca ggg gag cgc gct acc gat aag gca gct gtt ctg gaa gat ctc aag 1411 Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala Val Leu Glu Asp Leu Lys 425 430 435 cgc cca acc gaa ggc cgc ctc tac gac gtt gag ctg gca atg cgc ctt 1459 Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val Glu Leu Ala Met Arg Leu 440 445 450 ggc gca agc gtg gaa gaa ctc tac gaa gca tct tct att gat cct tgg 1507 Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala Ser Ser Ile Asp Pro Trp 455 460 465 ttc ctc gcc gag ctt gaa gct ctc gtg cag ttc cgc cag aag ctc gtt 1555 Phe Leu Ala Glu Leu Glu Ala Leu Val Gln Phe Arg Gln Lys Leu Val 470 475 480 485 gac gca cca ttc cta aac gaa gat ctc ctg cgc gaa gca aag ttc atg 1603 Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu Arg Glu Ala Lys Phe Met 490 495 500 ggt ctg tcc gac ctg cag atc gca gcc ctt cgc cca gag ttc gct ggc 1651 Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu Arg Pro Glu Phe Ala Gly 505 510 515 gaa gac ggc gta cgc acc ttg cgt ctg tcc cta ggc atc cgc cca gta 1699 Glu Asp Gly Val Arg Thr Leu Arg Leu Ser Leu Gly Ile Arg Pro Val 520 525 530 ttc aag act gtg gat acc tgt gca gca gag ttt gaa gct aag act ccg 1747 Phe Lys Thr Val Asp Thr Cys Ala Ala Glu Phe Glu Ala Lys Thr Pro 535 540 545 tac cac tac tcc gca tac gag ctg gat cca gca gct gag tct gag gtc 1795 Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro Ala Ala Glu Ser Glu Val 550 555 560 565 gca cca cag act gag cgt gaa aag gtc ctg atc ttg ggc tcc ggt cca 1843 Ala Pro Gln Thr Glu Arg Glu Lys Val Leu Ile Leu Gly Ser Gly Pro 570 575 580 aac cgc atc ggc cag ggc atc gag ttc gac tac tcc tgt gtt cac gca 1891 Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp Tyr Ser Cys Val His Ala 585 590 595 gct ctt gag ctc tcc cgc gtc ggc tac gaa act gtc atg gtc aac tgc 1939 Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu Thr Val Met Val Asn Cys 600 605 610 aac cca gag acc gtg tcc acc gac tac gac acc gct gac cgc ctg tac 1987 Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp Thr Ala Asp Arg Leu Tyr 615 620 625 ttc gag cca ctg acc ttc gaa gac gtc atg gag gtc tac cac gct gag 2035 Phe Glu Pro Leu Thr Phe Glu Asp Val Met Glu Val Tyr His Ala Glu 630 635 640 645 gcg cag tcc ggc acc gtc gca ggt gtt atc gtc cag ctt ggt ggc cag 2083 Ala Gln Ser Gly Thr Val Ala Gly Val Ile Val Gln Leu Gly Gly Gln 650 655 660 act cct ctg ggc ttg gca gat cgt ttg aag aag gct ggc gtc cct gtc 2131 Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys Lys Ala Gly Val Pro Val 665 670 675 att ggt acc tcc cca gag gca atc gac atg gct gag gac cgt ggc gag 2179 Ile Gly Thr Ser Pro Glu Ala Ile Asp Met Ala Glu Asp Arg Gly Glu 680 685 690 ttc ggt gca ctg ctg aac cgc gag cag ctt cct gct cca gca ttc ggc 2227 Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu Pro Ala Pro Ala Phe Gly 695 700 705 acc gca acc tct ttc gaa gag gct cgc aca gta gcc gat gag atc agc 2275 Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr Val Ala Asp Glu Ile Ser 710 715 720 725 tac cca gtg ctg gtt cgc cct tcc tac gtc ttg ggt ggc cgt ggc atg 2323 Tyr Pro Val Leu Val Arg Pro Ser Tyr Val Leu Gly Gly Arg Gly Met 730 735 740 gag att gtc tac gat gag gct tcc ctc gag gat tac atc aac cgc gca 2371 Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu Asp Tyr Ile Asn Arg Ala 745 750 755 act gag ttg tct tct gac cac cca gtg ctg gtt gac cgc ttc cta gac 2419 Thr Glu Leu Ser Ser Asp His Pro Val Leu Val Asp Arg Phe Leu Asp 760 765 770 aac gct att gag atc gac gtc gac gca ctg tgc gac ggc gac gag gtc 2467 Asn Ala Ile Glu Ile Asp Val Asp Ala Leu Cys Asp Gly Asp Glu Val 775 780 785 tac ctg gca ggc gtc atg gag cac atc gag gaa gcc ggc att cac tcc 2515 Tyr Leu Ala Gly Val Met Glu His Ile Glu Glu Ala Gly Ile His Ser 790 795 800 805 ggt gac tcc gca tgt gca ctt cct cca atg act ttg ggc gca cag gac 2563 Gly Asp Ser Ala Cys Ala Leu Pro Pro Met Thr Leu Gly Ala Gln Asp 810 815 820 atc gag aag gtc cgc gaa gca acc aag aag ctg gct ctg ggc atc ggt 2611 Ile Glu Lys Val Arg Glu Ala Thr Lys Lys Leu Ala Leu Gly Ile Gly 825 830 835 gta cag ggc ctg atg aac gtc cag tac gca ctc aag gac gac atc ctc 2659 Val Gln Gly Leu Met Asn Val Gln Tyr Ala Leu Lys Asp Asp Ile Leu 840 845 850 tac gtc atc gag gca aac cca cgt gca tcc cgc acc gtg ccg ttc gtc 2707 Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser Arg Thr Val Pro Phe Val 855 860 865 tcc aag gca acg ggc gtc aac ctg gcc aag gca gca tcc cgt atc gca 2755 Ser Lys Ala Thr Gly Val Asn Leu Ala Lys Ala Ala Ser Arg Ile Ala 870 875 880 885 gtg ggc gcc acc atc aag gat ctc caa gat gag ggc atg att cct acc 2803 Val Gly Ala Thr Ile Lys Asp Leu Gln Asp Glu Gly Met Ile Pro Thr 890 895 900 gag tac gac ggc ggc tcc ttg cca ctg gac gct cca atc gct gtg aag 2851 Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp Ala Pro Ile Ala Val Lys 905 910 915 gaa gca gtg ttg ccg ttc aac cgc ttc cgt cgc cca gat gga aag acc 2899 Glu Ala Val Leu Pro Phe Asn Arg Phe Arg Arg Pro Asp Gly Lys Thr 920 925 930 ctg gac acc ctg ctt tcc cca gag atg aag tcc act ggc gag gtc atg 2947 Leu Asp Thr Leu Leu Ser Pro Glu Met Lys Ser Thr Gly Glu Val Met 935 940 945 ggc ttg gcc aac aac ttc ggc gct gca tat gca aag gct gaa gct ggc 2995 Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr Ala Lys Ala Glu Ala Gly 950 955 960 965 gcg ttt ggt gca ttg cca acc gaa ggc acc gtc ttc gtg acc gtg gct 3043 Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr Val Phe Val Thr Val Ala 970 975 980 aac cgc gac aag cgc acc ctg atc ctg cca atc cag cgc ctg gcg ttg 3091 Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro Ile Gln Arg Leu Ala Leu 985 990 995 atg ggc tac aag atc ctc gcc acc gaa ggc acc gca ggc atg ctg cgc 3139 Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly Thr Ala Gly Met Leu Arg 1000 1005 1010 cgc aac ggc att gag tgt gaa gtt gtg ctc aag gct tcc gac atc cgc 3187 Arg Asn Gly Ile Glu Cys Glu Val Val Leu Lys Ala Ser Asp Ile Arg 1015 1020 1025 gaa ggt gta gag ggc aag tcc atc gtg gat cgt atc cgc gaa ggc gaa 3235 Glu Gly Val Glu Gly Lys Ser Ile Val Asp Arg Ile Arg Glu Gly Glu 1030 1035 1040 1045 gtt gac ctc atc ctc aac acc cca gct ggt tct gct ggc gct cgc cac 3283 Val Asp Leu Ile Leu Asn Thr Pro Ala Gly Ser Ala Gly Ala Arg His 1050 1055 1060 gat ggc tac gat atc cgc gca gca gca gtg acc gtg ggt gtt ccg ctg 3331 Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val Thr Val Gly Val Pro Leu 1065 1070 1075 atc acc act gtt cag ggt gtc acc gca gct gtc cag ggc ata gag gcc 3379 Ile Thr Thr Val Gln Gly Val Thr Ala Ala Val Gln Gly Ile Glu Ala 1080 1085 1090 ctg cgt gag ggc gtt gtc agc gtc cgc gcg ctg cag gaa ctc gac cac 3427 Leu Arg Glu Gly Val Val Ser Val Arg Ala Leu Gln Glu Leu Asp His 1095 1100 1105 gca gtc aag gct taagccctat gacattcggc gag 3462 Ala Val Lys Ala 1110 <210> 1000 <211> 1113 <212> PRT <213> Corynebacterium glutamicum <400> 1000 Met Pro Lys Arg Ser Asp Ile Asn His Val Leu Val Ile Gly Ser Gly 1 5 10 15 Pro Ile Val Ile Gly Gln Ala Cys Glu Phe Asp Tyr Ser Gly Thr Gln 20 25 30 Ala Cys Arg Val Leu Lys Glu Glu Gly Leu Arg Val Thr Leu Ile Asn 35 40 45 Ser Asn Pro Ala Thr Ile Met Thr Asp Pro Glu Met Ala Asp His Thr 50 55 60 Tyr Val Glu Pro Ile Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala Lys 65 70 75 80 Glu Ile Glu Gln Gly His Pro Ile Asp Ala Val Leu Ala Thr Leu Gly 85 90 95 Gly Gln Thr Ala Leu Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly Ile 100 105 110 Leu Glu Lys Tyr Gly Val Glu Leu Ile Gly Ala Asp Ile Asp Ala Ile 115 120 125 Glu Arg Gly Glu Asp Arg Gln Lys Phe Lys Asp Ile Val Thr Thr Ile 130 135 140 Gly Gly Glu Ser Ala Arg Ser Arg Val Cys His Asn Met Glu Glu Val 145 150 155 160 His Glu Thr Val Ala Glu Leu Gly Leu Pro Val Val Val Arg Pro Ser 165 170 175 Phe Thr Met Gly Gly Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu Asp 180 185 190 Leu Glu Arg Ile Ala Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala Asn 195 200 205 Val Leu Ile Glu Glu Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu Glu 210 215 220 Leu Met Arg Asp Thr Ala Asp Asn Val Val Val Ile Cys Ser Ile Glu 225 230 235 240 Asn Val Asp Ala Leu Gly Val His Thr Gly Asp Ser Val Thr Val Ala 245 250 255 Pro Ala Leu Thr Leu Thr Asp Arg Glu Phe Gln Lys Met Arg Asp Gln 260 265 270 Gly Ile Ala Ile Ile Arg Glu Val Gly Val Asp Thr Gly Gly Cys Asn 275 280 285 Ile Gln Phe Ala Ile Asn Pro Val Asp Gly Arg Ile Ile Thr Ile Glu 290 295 300 Met Asn Pro Arg Val Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala Thr 305 310 315 320 Gly Phe Pro Ile Ala Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr Thr 325 330 335 Leu Asp Glu Ile Thr Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala Phe 340 345 350 Glu Pro Thr Ile Asp Tyr Val Val Val Lys Ala Pro Arg Phe Ala Phe 355 360 365 Glu Lys Phe Val Gly Ala Asp Asp Thr Leu Thr Thr Thr Met Lys Ser 370 375 380 Val Gly Glu Val Met Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu Asn 385 390 395 400 Lys Ala Leu Arg Ser Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr Lys 405 410 415 Pro Asp Glu Phe Phe Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala Val 420 425 430 Leu Glu Asp Leu Lys Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val Glu 435 440 445 Leu Ala Met Arg Leu Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala Ser 450 455 460 Ser Ile Asp Pro Trp Phe Leu Ala Glu Leu Glu Ala Leu Val Gln Phe 465 470 475 480 Arg Gln Lys Leu Val Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu Arg 485 490 495 Glu Ala Lys Phe Met Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu Arg 500 505 510 Pro Glu Phe Ala Gly Glu Asp Gly Val Arg Thr Leu Arg Leu Ser Leu 515 520 525 Gly Ile Arg Pro Val Phe Lys Thr Val Asp Thr Cys Ala Ala Glu Phe 530 535 540 Glu Ala Lys Thr Pro Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro Ala 545 550 555 560 Ala Glu Ser Glu Val Ala Pro Gln Thr Glu Arg Glu Lys Val Leu Ile 565 570 575 Leu Gly Ser Gly Pro Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp Tyr 580 585 590 Ser Cys Val His Ala Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu Thr 595 600 605 Val Met Val Asn Cys Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp Thr 610 615 620 Ala Asp Arg Leu Tyr Phe Glu Pro Leu Thr Phe Glu Asp Val Met Glu 625 630 635 640 Val Tyr His Ala Glu Ala Gln Ser Gly Thr Val Ala Gly Val Ile Val 645 650 655 Gln Leu Gly Gly Gln Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys Lys 660 665 670 Ala Gly Val Pro Val Ile Gly Thr Ser Pro Glu Ala Ile Asp Met Ala 675 680 685 Glu Asp Arg Gly Glu Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu Pro 690 695 700 Ala Pro Ala Phe Gly Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr Val 705 710 715 720 Ala Asp Glu Ile Ser Tyr Pro Val Leu Val Arg Pro Ser Tyr Val Leu 725 730 735 Gly Gly Arg Gly Met Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu Asp 740 745 750 Tyr Ile Asn Arg Ala Thr Glu Leu Ser Ser Asp His Pro Val Leu Val 755 760 765 Asp Arg Phe Leu Asp Asn Ala Ile Glu Ile Asp Val Asp Ala Leu Cys 770 775 780 Asp Gly Asp Glu Val Tyr Leu Ala Gly Val Met Glu His Ile Glu Glu 785 790 795 800 Ala Gly Ile His Ser Gly Asp Ser Ala Cys Ala Leu Pro Pro Met Thr 805 810 815 Leu Gly Ala Gln Asp Ile Glu Lys Val Arg Glu Ala Thr Lys Lys Leu 820 825 830 Ala Leu Gly Ile Gly Val Gln Gly Leu Met Asn Val Gln Tyr Ala Leu 835 840 845 Lys Asp Asp Ile Leu Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser Arg 850 855 860 Thr Val Pro Phe Val Ser Lys Ala Thr Gly Val Asn Leu Ala Lys Ala 865 870 875 880 Ala Ser Arg Ile Ala Val Gly Ala Thr Ile Lys Asp Leu Gln Asp Glu 885 890 895 Gly Met Ile Pro Thr Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp Ala 900 905 910 Pro Ile Ala Val Lys Glu Ala Val Leu Pro Phe Asn Arg Phe Arg Arg 915 920 925 Pro Asp Gly Lys Thr Leu Asp Thr Leu Leu Ser Pro Glu Met Lys Ser 930 935 940 Thr Gly Glu Val Met Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr Ala 945 950 955 960 Lys Ala Glu Ala Gly Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr Val 965 970 975 Phe Val Thr Val Ala Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro Ile 980 985 990 Gln Arg Leu Ala Leu Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly Thr 995 1000 1005 Ala Gly Met Leu Arg Arg Asn Gly Ile Glu Cys Glu Val Val Leu Lys 1010 1015 1020 Ala Ser Asp Ile Arg Glu Gly Val Glu Gly Lys Ser Ile Val Asp Arg 1025 1030 1035 1040 Ile Arg Glu Gly Glu Val Asp Leu Ile Leu Asn Thr Pro Ala Gly Ser 1045 1050 1055 Ala Gly Ala Arg His Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val Thr 1060 1065 1070 Val Gly Val Pro Leu Ile Thr Thr Val Gln Gly Val Thr Ala Ala Val 1075 1080 1085 Gln Gly Ile Glu Ala Leu Arg Glu Gly Val Val Ser Val Arg Ala Leu 1090 1095 1100 Gln Glu Leu Asp His Ala Val Lys Ala 1105 1110 <210> 1001 <211> 3221 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(3198) <223> FRXA02234 <400> 1001 ggc tcc aac cca gca acg atc atg acc gac cca gaa atg gct gac cac 48 Gly Ser Asn Pro Ala Thr Ile Met Thr Asp Pro Glu Met Ala Asp His 1 5 10 15 acc tac gtg gag cca atc gag ccg gaa tac atc gac aag att ttc gct 96 Thr Tyr Val Glu Pro Ile Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala 20 25 30 aag gaa atc gag cag ggc cac cca atc gac gcc gtc ctg gca acc ctt 144 Lys Glu Ile Glu Gln Gly His Pro Ile Asp Ala Val Leu Ala Thr Leu 35 40 45 ggt ggc cag act gca ctt aac gca gct atc cag ctg gat cgc ctc ggc 192 Gly Gly Gln Thr Ala Leu Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly 50 55 60 atc ctg gaa aag tac ggc gtt gaa ctc atc ggt gca gac atc gat gcc 240 Ile Leu Glu Lys Tyr Gly Val Glu Leu Ile Gly Ala Asp Ile Asp Ala 65 70 75 80 att gag cgc ggc gaa gat cgc cag aag ttc aag gat att gtc acc acc 288 Ile Glu Arg Gly Glu Asp Arg Gln Lys Phe Lys Asp Ile Val Thr Thr 85 90 95 atc ggt ggc gaa tcc gcg cgt tcc cgc gtc tgc cac aac atg gaa gaa 336 Ile Gly Gly Glu Ser Ala Arg Ser Arg Val Cys His Asn Met Glu Glu 100 105 110 gtc cac gag act gtc gca gaa ctc ggc ctt cca gta gtc gtg cgt cca 384 Val His Glu Thr Val Ala Glu Leu Gly Leu Pro Val Val Val Arg Pro 115 120 125 tcc ttc act atg ggt ggc ctg ggc tcc ggt ctt gca tac aac acc gaa 432 Ser Phe Thr Met Gly Gly Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu 130 135 140 gac ctt gag cgc atc gct ggt ggc gga ctt gct gca tct cct gaa gca 480 Asp Leu Glu Arg Ile Ala Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala 145 150 155 160 aac gtc ttg atc gaa gaa tcc atc ctt ggt tgg aag gaa ttc gag ctc 528 Asn Val Leu Ile Glu Glu Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu 165 170 175 gag ctc atg cgc gat acc gca gac aac gtt gtg gtt atc tgc tcc att 576 Glu Leu Met Arg Asp Thr Ala Asp Asn Val Val Val Ile Cys Ser Ile 180 185 190 gaa aac gtc gac gca ctg ggc gtg cac acc ggc gac tct gtc acc gtg 624 Glu Asn Val Asp Ala Leu Gly Val His Thr Gly Asp Ser Val Thr Val 195 200 205 gca cct gcc ctg acc ctg act gac cgt gaa ttc cag aag atg cgc gat 672 Ala Pro Ala Leu Thr Leu Thr Asp Arg Glu Phe Gln Lys Met Arg Asp 210 215 220 cag ggt atc gcc atc atc cgc gag gtc ggc gtg gac acc ggt gga tgt 720 Gln Gly Ile Ala Ile Ile Arg Glu Val Gly Val Asp Thr Gly Gly Cys 225 230 235 240 aac atc cag ttc gcc atc aac cca gtt gat ggc cgc atc atc acc att 768 Asn Ile Gln Phe Ala Ile Asn Pro Val Asp Gly Arg Ile Ile Thr Ile 245 250 255 gag atg aac cca cgt gtg tct cgt tcc tcc gct ctg gca tcc aag gca 816 Glu Met Asn Pro Arg Val Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala 260 265 270 acg ggc ttc cca att gcc aag atg gct gcc aag ctg gct atc gga tac 864 Thr Gly Phe Pro Ile Ala Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr 275 280 285 acc ctg gat gag atc acc aac gac atc act ggt gaa acc cca gct gcg 912 Thr Leu Asp Glu Ile Thr Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala 290 295 300 ttt gag ccc acc atc gac tac gtc gtg gtc aag gcc cca cgc ttt gct 960 Phe Glu Pro Thr Ile Asp Tyr Val Val Val Lys Ala Pro Arg Phe Ala 305 310 315 320 ttc gag aag ttt gtc ggc gct gat gac act ttg acc acc acc atg aag 1008 Phe Glu Lys Phe Val Gly Ala Asp Asp Thr Leu Thr Thr Thr Met Lys 325 330 335 tcc gtc ggt gag gtc atg tcc ctg ggc cgc aac tac att gca gca ctg 1056 Ser Val Gly Glu Val Met Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu 340 345 350 aac aag gca ctg cgt tcc ctg gaa acc aag cag cag ggt ttc tgg acc 1104 Asn Lys Ala Leu Arg Ser Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr 355 360 365 aag cct gat gag ttc ttc gca ggg gag cgc gct acc gat aag gca gct 1152 Lys Pro Asp Glu Phe Phe Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala 370 375 380 gtt ctg gaa gat ctc aag cgc cca acc gaa ggc cgc ctc tac gac gtt 1200 Val Leu Glu Asp Leu Lys Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val 385 390 395 400 gag ctg gca atg cgc ctt ggc gca agc gtg gaa gaa ctc tac gaa gca 1248 Glu Leu Ala Met Arg Leu Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala 405 410 415 tct tct att gat cct tgg ttc ctc gcc gag ctt gaa gct ctc gtg cag 1296 Ser Ser Ile Asp Pro Trp Phe Leu Ala Glu Leu Glu Ala Leu Val Gln 420 425 430 ttc cgc cag aag ctc gtt gac gca cca ttc cta aac gaa gat ctc ctg 1344 Phe Arg Gln Lys Leu Val Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu 435 440 445 cgc gaa gca aag ttc atg ggt ctg tcc gac ctg cag atc gca gcc ctt 1392 Arg Glu Ala Lys Phe Met Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu 450 455 460 cgc cca gag ttc gct ggc gaa gac ggc gta cgc acc ttg cgt ctg tcc 1440 Arg Pro Glu Phe Ala Gly Glu Asp Gly Val Arg Thr Leu Arg Leu Ser 465 470 475 480 cta ggc atc cgc cca gta ttc aag act gtg gat acc tgt gca gca gag 1488 Leu Gly Ile Arg Pro Val Phe Lys Thr Val Asp Thr Cys Ala Ala Glu 485 490 495 ttt gaa gct aag act ccg tac cac tac tcc gca tac gag ctg gat cca 1536 Phe Glu Ala Lys Thr Pro Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro 500 505 510 gca gct gag tct gag gtc gca cca cag act gag cgt gaa aag gtc ctg 1584 Ala Ala Glu Ser Glu Val Ala Pro Gln Thr Glu Arg Glu Lys Val Leu 515 520 525 atc ttg ggc tcc ggt cca aac cgc atc ggc cag ggc atc gag ttc gac 1632 Ile Leu Gly Ser Gly Pro Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp 530 535 540 tac tcc tgt gtt cac gca gct ctt gag ctc tcc cgc gtc ggc tac gaa 1680 Tyr Ser Cys Val His Ala Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu 545 550 555 560 act gtc atg gtc aac tgc aac cca gag acc gtg tcc acc gac tac gac 1728 Thr Val Met Val Asn Cys Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp 565 570 575 acc gct gac cgc ctg tac ttc gag cca ctg acc ttc gaa gac gtc atg 1776 Thr Ala Asp Arg Leu Tyr Phe Glu Pro Leu Thr Phe Glu Asp Val Met 580 585 590 gag gtc tac cac gct gag gcg cag tcc ggc acc gtc gca ggt gtt atc 1824 Glu Val Tyr His Ala Glu Ala Gln Ser Gly Thr Val Ala Gly Val Ile 595 600 605 gtc cag ctt ggt ggc cag act cct ctg ggc ttg gca gat cgt ttg aag 1872 Val Gln Leu Gly Gly Gln Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys 610 615 620 aag gct ggc gtc cct gtc att ggt acc tcc cca gag gca atc gac atg 1920 Lys Ala Gly Val Pro Val Ile Gly Thr Ser Pro Glu Ala Ile Asp Met 625 630 635 640 gct gag gac cgt ggc gag ttc ggt gca ctg ctg aac cgc gag cag ctt 1968 Ala Glu Asp Arg Gly Glu Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu 645 650 655 cct gct cca gca ttc ggc acc gca acc tct ttc gaa gag gct cgc aca 2016 Pro Ala Pro Ala Phe Gly Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr 660 665 670 gta gcc gat gag atc agc tac cca gtg ctg gtt cgc cct tcc tac gtc 2064 Val Ala Asp Glu Ile Ser Tyr Pro Val Leu Val Arg Pro Ser Tyr Val 675 680 685 ttg ggt ggc cgt ggc atg gag att gtc tac gat gag gct tcc ctc gag 2112 Leu Gly Gly Arg Gly Met Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu 690 695 700 gat tac atc aac cgc gca act gag ttg tct tct gac cac cca gtg ctg 2160 Asp Tyr Ile Asn Arg Ala Thr Glu Leu Ser Ser Asp His Pro Val Leu 705 710 715 720 gtt gac cgc ttc cta gac aac gct att gag atc gac gtc gac gca ctg 2208 Val Asp Arg Phe Leu Asp Asn Ala Ile Glu Ile Asp Val Asp Ala Leu 725 730 735 tgc gac ggc gac gag gtc tac ctg gca ggc gtc atg gag cac atc gag 2256 Cys Asp Gly Asp Glu Val Tyr Leu Ala Gly Val Met Glu His Ile Glu 740 745 750 gaa gcc ggc att cac tcc ggt gac tcc gca tgt gca ctt cct cca atg 2304 Glu Ala Gly Ile His Ser Gly Asp Ser Ala Cys Ala Leu Pro Pro Met 755 760 765 act ttg ggc gca cag gac atc gag aag gtc cgc gaa gca acc aag aag 2352 Thr Leu Gly Ala Gln Asp Ile Glu Lys Val Arg Glu Ala Thr Lys Lys 770 775 780 ctg gct ctg ggc atc ggt gta cag ggc ctg atg aac gtc cag tac gca 2400 Leu Ala Leu Gly Ile Gly Val Gln Gly Leu Met Asn Val Gln Tyr Ala 785 790 795 800 ctc aag gac gac atc ctc tac gtc atc gag gca aac cca cgt gca tcc 2448 Leu Lys Asp Asp Ile Leu Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser 805 810 815 cgc acc gtg ccg ttc gtc tcc aag gca acg ggc gtc aac ctg gcc aag 2496 Arg Thr Val Pro Phe Val Ser Lys Ala Thr Gly Val Asn Leu Ala Lys 820 825 830 gca gca tcc cgt atc gca gtg ggc gcc acc atc aag gat ctc caa gat 2544 Ala Ala Ser Arg Ile Ala Val Gly Ala Thr Ile Lys Asp Leu Gln Asp 835 840 845 gag ggc atg att cct acc gag tac gac ggc ggc tcc ttg cca ctg gac 2592 Glu Gly Met Ile Pro Thr Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp 850 855 860 gct cca atc gct gtg aag gaa gca gtg ttg ccg ttc aac cgc ttc cgt 2640 Ala Pro Ile Ala Val Lys Glu Ala Val Leu Pro Phe Asn Arg Phe Arg 865 870 875 880 cgc cca gat gga aag acc ctg gac acc ctg ctt tcc cca gag atg aag 2688 Arg Pro Asp Gly Lys Thr Leu Asp Thr Leu Leu Ser Pro Glu Met Lys 885 890 895 tcc act ggc gag gtc atg ggc ttg gcc aac aac ttc ggc gct gca tat 2736 Ser Thr Gly Glu Val Met Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr 900 905 910 gca aag gct gaa gct ggc gcg ttt ggt gca ttg cca acc gaa ggc acc 2784 Ala Lys Ala Glu Ala Gly Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr 915 920 925 gtc ttc gtg acc gtg gct aac cgc gac aag cgc acc ctg atc ctg cca 2832 Val Phe Val Thr Val Ala Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro 930 935 940 atc cag cgc ctg gcg ttg atg ggc tac aag atc ctc gcc acc gaa ggc 2880 Ile Gln Arg Leu Ala Leu Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly 945 950 955 960 acc gca ggc atg ctg cgc cgc aac ggc att gag tgt gaa gtt gtg ctc 2928 Thr Ala Gly Met Leu Arg Arg Asn Gly Ile Glu Cys Glu Val Val Leu 965 970 975 aag gct tcc gac atc cgc gaa ggt gta gag ggc aag tcc atc gtg gat 2976 Lys Ala Ser Asp Ile Arg Glu Gly Val Glu Gly Lys Ser Ile Val Asp 980 985 990 cgt atc cgc gaa ggc gaa gtt gac ctc atc ctc aac acc cca gct ggt 3024 Arg Ile Arg Glu Gly Glu Val Asp Leu Ile Leu Asn Thr Pro Ala Gly 995 1000 1005 tct gct ggc gct cgc cac gat ggc tac gat atc cgc gca gca gca gtg 3072 Ser Ala Gly Ala Arg His Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val 1010 1015 1020 acc gtg ggt gtt ccg ctg atc acc act gtt cag ggt gtc acc gca gct 3120 Thr Val Gly Val Pro Leu Ile Thr Thr Val Gln Gly Val Thr Ala Ala 1025 1030 1035 1040 gtc cag ggc ata gag gcc ctg cgt gag ggc gtt gtc agc gtc cgc gcg 3168 Val Gln Gly Ile Glu Ala Leu Arg Glu Gly Val Val Ser Val Arg Ala 1045 1050 1055 ctg cag gaa ctc gac cac gca gtc aag gct taagccctat gacattcggc 3218 Leu Gln Glu Leu Asp His Ala Val Lys Ala 1060 1065 gag 3221 <210> 1002 <211> 1066 <212> PRT <213> Corynebacterium glutamicum <400> 1002 Gly Ser Asn Pro Ala Thr Ile Met Thr Asp Pro Glu Met Ala Asp His 1 5 10 15 Thr Tyr Val Glu Pro Ile Glu Pro Glu Tyr Ile Asp Lys Ile Phe Ala 20 25 30 Lys Glu Ile Glu Gln Gly His Pro Ile Asp Ala Val Leu Ala Thr Leu 35 40 45 Gly Gly Gln Thr Ala Leu Asn Ala Ala Ile Gln Leu Asp Arg Leu Gly 50 55 60 Ile Leu Glu Lys Tyr Gly Val Glu Leu Ile Gly Ala Asp Ile Asp Ala 65 70 75 80 Ile Glu Arg Gly Glu Asp Arg Gln Lys Phe Lys Asp Ile Val Thr Thr 85 90 95 Ile Gly Gly Glu Ser Ala Arg Ser Arg Val Cys His Asn Met Glu Glu 100 105 110 Val His Glu Thr Val Ala Glu Leu Gly Leu Pro Val Val Val Arg Pro 115 120 125 Ser Phe Thr Met Gly Gly Leu Gly Ser Gly Leu Ala Tyr Asn Thr Glu 130 135 140 Asp Leu Glu Arg Ile Ala Gly Gly Gly Leu Ala Ala Ser Pro Glu Ala 145 150 155 160 Asn Val Leu Ile Glu Glu Ser Ile Leu Gly Trp Lys Glu Phe Glu Leu 165 170 175 Glu Leu Met Arg Asp Thr Ala Asp Asn Val Val Val Ile Cys Ser Ile 180 185 190 Glu Asn Val Asp Ala Leu Gly Val His Thr Gly Asp Ser Val Thr Val 195 200 205 Ala Pro Ala Leu Thr Leu Thr Asp Arg Glu Phe Gln Lys Met Arg Asp 210 215 220 Gln Gly Ile Ala Ile Ile Arg Glu Val Gly Val Asp Thr Gly Gly Cys 225 230 235 240 Asn Ile Gln Phe Ala Ile Asn Pro Val Asp Gly Arg Ile Ile Thr Ile 245 250 255 Glu Met Asn Pro Arg Val Ser Arg Ser Ser Ala Leu Ala Ser Lys Ala 260 265 270 Thr Gly Phe Pro Ile Ala Lys Met Ala Ala Lys Leu Ala Ile Gly Tyr 275 280 285 Thr Leu Asp Glu Ile Thr Asn Asp Ile Thr Gly Glu Thr Pro Ala Ala 290 295 300 Phe Glu Pro Thr Ile Asp Tyr Val Val Val Lys Ala Pro Arg Phe Ala 305 310 315 320 Phe Glu Lys Phe Val Gly Ala Asp Asp Thr Leu Thr Thr Thr Met Lys 325 330 335 Ser Val Gly Glu Val Met Ser Leu Gly Arg Asn Tyr Ile Ala Ala Leu 340 345 350 Asn Lys Ala Leu Arg Ser Leu Glu Thr Lys Gln Gln Gly Phe Trp Thr 355 360 365 Lys Pro Asp Glu Phe Phe Ala Gly Glu Arg Ala Thr Asp Lys Ala Ala 370 375 380 Val Leu Glu Asp Leu Lys Arg Pro Thr Glu Gly Arg Leu Tyr Asp Val 385 390 395 400 Glu Leu Ala Met Arg Leu Gly Ala Ser Val Glu Glu Leu Tyr Glu Ala 405 410 415 Ser Ser Ile Asp Pro Trp Phe Leu Ala Glu Leu Glu Ala Leu Val Gln 420 425 430 Phe Arg Gln Lys Leu Val Asp Ala Pro Phe Leu Asn Glu Asp Leu Leu 435 440 445 Arg Glu Ala Lys Phe Met Gly Leu Ser Asp Leu Gln Ile Ala Ala Leu 450 455 460 Arg Pro Glu Phe Ala Gly Glu Asp Gly Val Arg Thr Leu Arg Leu Ser 465 470 475 480 Leu Gly Ile Arg Pro Val Phe Lys Thr Val Asp Thr Cys Ala Ala Glu 485 490 495 Phe Glu Ala Lys Thr Pro Tyr His Tyr Ser Ala Tyr Glu Leu Asp Pro 500 505 510 Ala Ala Glu Ser Glu Val Ala Pro Gln Thr Glu Arg Glu Lys Val Leu 515 520 525 Ile Leu Gly Ser Gly Pro Asn Arg Ile Gly Gln Gly Ile Glu Phe Asp 530 535 540 Tyr Ser Cys Val His Ala Ala Leu Glu Leu Ser Arg Val Gly Tyr Glu 545 550 555 560 Thr Val Met Val Asn Cys Asn Pro Glu Thr Val Ser Thr Asp Tyr Asp 565 570 575 Thr Ala Asp Arg Leu Tyr Phe Glu Pro Leu Thr Phe Glu Asp Val Met 580 585 590 Glu Val Tyr His Ala Glu Ala Gln Ser Gly Thr Val Ala Gly Val Ile 595 600 605 Val Gln Leu Gly Gly Gln Thr Pro Leu Gly Leu Ala Asp Arg Leu Lys 610 615 620 Lys Ala Gly Val Pro Val Ile Gly Thr Ser Pro Glu Ala Ile Asp Met 625 630 635 640 Ala Glu Asp Arg Gly Glu Phe Gly Ala Leu Leu Asn Arg Glu Gln Leu 645 650 655 Pro Ala Pro Ala Phe Gly Thr Ala Thr Ser Phe Glu Glu Ala Arg Thr 660 665 670 Val Ala Asp Glu Ile Ser Tyr Pro Val Leu Val Arg Pro Ser Tyr Val 675 680 685 Leu Gly Gly Arg Gly Met Glu Ile Val Tyr Asp Glu Ala Ser Leu Glu 690 695 700 Asp Tyr Ile Asn Arg Ala Thr Glu Leu Ser Ser Asp His Pro Val Leu 705 710 715 720 Val Asp Arg Phe Leu Asp Asn Ala Ile Glu Ile Asp Val Asp Ala Leu 725 730 735 Cys Asp Gly Asp Glu Val Tyr Leu Ala Gly Val Met Glu His Ile Glu 740 745 750 Glu Ala Gly Ile His Ser Gly Asp Ser Ala Cys Ala Leu Pro Pro Met 755 760 765 Thr Leu Gly Ala Gln Asp Ile Glu Lys Val Arg Glu Ala Thr Lys Lys 770 775 780 Leu Ala Leu Gly Ile Gly Val Gln Gly Leu Met Asn Val Gln Tyr Ala 785 790 795 800 Leu Lys Asp Asp Ile Leu Tyr Val Ile Glu Ala Asn Pro Arg Ala Ser 805 810 815 Arg Thr Val Pro Phe Val Ser Lys Ala Thr Gly Val Asn Leu Ala Lys 820 825 830 Ala Ala Ser Arg Ile Ala Val Gly Ala Thr Ile Lys Asp Leu Gln Asp 835 840 845 Glu Gly Met Ile Pro Thr Glu Tyr Asp Gly Gly Ser Leu Pro Leu Asp 850 855 860 Ala Pro Ile Ala Val Lys Glu Ala Val Leu Pro Phe Asn Arg Phe Arg 865 870 875 880 Arg Pro Asp Gly Lys Thr Leu Asp Thr Leu Leu Ser Pro Glu Met Lys 885 890 895 Ser Thr Gly Glu Val Met Gly Leu Ala Asn Asn Phe Gly Ala Ala Tyr 900 905 910 Ala Lys Ala Glu Ala Gly Ala Phe Gly Ala Leu Pro Thr Glu Gly Thr 915 920 925 Val Phe Val Thr Val Ala Asn Arg Asp Lys Arg Thr Leu Ile Leu Pro 930 935 940 Ile Gln Arg Leu Ala Leu Met Gly Tyr Lys Ile Leu Ala Thr Glu Gly 945 950 955 960 Thr Ala Gly Met Leu Arg Arg Asn Gly Ile Glu Cys Glu Val Val Leu 965 970 975 Lys Ala Ser Asp Ile Arg Glu Gly Val Glu Gly Lys Ser Ile Val Asp 980 985 990 Arg Ile Arg Glu Gly Glu Val Asp Leu Ile Leu Asn Thr Pro Ala Gly 995 1000 1005 Ser Ala Gly Ala Arg His Asp Gly Tyr Asp Ile Arg Ala Ala Ala Val 1010 1015 1020 Thr Val Gly Val Pro Leu Ile Thr Thr Val Gln Gly Val Thr Ala Ala 1025 1030 1035 1040 Val Gln Gly Ile Glu Ala Leu Arg Glu Gly Val Val Ser Val Arg Ala 1045 1050 1055 Leu Gln Glu Leu Asp His Ala Val Lys Ala 1060 1065 <210> 1003 <211> 424 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(424) <223> RXN00450 <400> 1003 tttgcgatga catggatttg gatccttccg aacaattgct gcgcatcgcg gaagaactcg 60 gttttgataa tgatctggct cgggtggtgg gattcgacta gtg ggc gtt tta cct 115 Val Gly Val Leu Pro 1 5 gtg cag gcg cgc atc aaa gac gat gag cgc cgc atg cgc cat gct ttg 163 Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg Met Arg His Ala Leu 10 15 20 gat att gct cgc caa acc cct gag ggg gac gtt ccc gtt ggc gcc gtc 211 Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val Pro Val Gly Ala Val 25 30 35 att tac gcg ccg acc ggg gag atc ctg gcg acc gca acg aac cgt cga 259 Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr Ala Thr Asn Arg Arg 40 45 50 gaa gca gac cgc gat ccc acg gcc cac gcc gaa att att gct tta cga 307 Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu Ile Ile Ala Leu Arg 55 60 65 cga gcc gcc cgc cgt ttt tcc gac ggc tgg cgg ctg agt gac tgc acc 355 Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg Leu Ser Asp Cys Thr 70 75 80 85 gcg gtg gtc acc ttg gag ccc tgc agt atg tgc gcc ggc gcc ttg gtg 403 Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys Ala Gly Ala Leu Val 90 95 100 ggt gct cga atc gga cgc atc 424 Gly Ala Arg Ile Gly Arg Ile 105 <210> 1004 <211> 108 <212> PRT <213> Corynebacterium glutamicum <400> 1004 Val Gly Val Leu Pro Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg 1 5 10 15 Met Arg His Ala Leu Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val 20 25 30 Pro Val Gly Ala Val Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr 35 40 45 Ala Thr Asn Arg Arg Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu 50 55 60 Ile Ile Ala Leu Arg Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg 65 70 75 80 Leu Ser Asp Cys Thr Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys 85 90 95 Ala Gly Ala Leu Val Gly Ala Arg Ile Gly Arg Ile 100 105 <210> 1005 <211> 418 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(418) <223> FRXA00450 <400> 1005 tttgcgatga catggatttg gatccttccg aacaattgct gcgcatcgcg gaagaactcg 60 gttttgataa tgatctggct cgggtggtgg gattcgacta gtg ggc gtt tta cct 115 Val Gly Val Leu Pro 1 5 gtg cag gcg cgc atc aaa gac gat gag cgc cgc atg cgc cat gct ttg 163 Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg Met Arg His Ala Leu 10 15 20 gat att gct cgc caa acc cct gag ggg gac gtt ccc gtt ggc gcc gtc 211 Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val Pro Val Gly Ala Val 25 30 35 att tac gcg ccg acc ggg gag atc ctg gcg acc gca acg aac cgt cga 259 Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr Ala Thr Asn Arg Arg 40 45 50 gaa gca gac cgc gat ccc acg gcc cac gcc gaa att att gct tta cga 307 Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu Ile Ile Ala Leu Arg 55 60 65 cga gcc gcc cgc cgt ttt tcc gac ggc tgg cgg ctg agt gac tgc acc 355 Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg Leu Ser Asp Cys Thr 70 75 80 85 gcg gtg gtc acc ttg gag ccc tgc agt atg tgc gcc ggc gcc ttg gtg 403 Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys Ala Gly Ala Leu Val 90 95 100 ggt gct cga atc gga 418 Gly Ala Arg Ile Gly 105 <210> 1006 <211> 106 <212> PRT <213> Corynebacterium glutamicum <400> 1006 Val Gly Val Leu Pro Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg 1 5 10 15 Met Arg His Ala Leu Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val 20 25 30 Pro Val Gly Ala Val Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr 35 40 45 Ala Thr Asn Arg Arg Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu 50 55 60 Ile Ile Ala Leu Arg Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg 65 70 75 80 Leu Ser Asp Cys Thr Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys 85 90 95 Ala Gly Ala Leu Val Gly Ala Arg Ile Gly 100 105 <210> 1007 <211> 1368 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1345) <223> RXN02272 <400> 1007 tatttaactc cacactaata cctgtcaagc aatagaatag atagcatctg gatcctccag 60 agtttgaaaa tatgccttga catgtagaaa tggagttctt gtg cgc att aca aac 115 Val Arg Ile Thr Asn 1 5 gcc cag gtt aag aac tac gca gag tta gtt gat atc acc ata gag ggt 163 Ala Gln Val Lys Asn Tyr Ala Glu Leu Val Asp Ile Thr Ile Glu Gly 10 15 20 gaa aaa att tcc tcg att acc ccc tct tca att cga tca gaa gaa gat 211 Glu Lys Ile Ser Ser Ile Thr Pro Ser Ser Ile Arg Ser Glu Glu Asp 25 30 35 cac cgc gcg gac gat tac gat gcc gca gga aga ctg gtc gca ccc cag 259 His Arg Ala Asp Asp Tyr Asp Ala Ala Gly Arg Leu Val Ala Pro Gln 40 45 50 ttc gcc gaa gca cac atc cac ctt gac tac gca aac acc gct gga atc 307 Phe Ala Glu Ala His Ile His Leu Asp Tyr Ala Asn Thr Ala Gly Ile 55 60 65 cct cgc gaa aac tct tcc ggc aca ctt ttt gaa gcc atc gaa atc tgg 355 Pro Arg Glu Asn Ser Ser Gly Thr Leu Phe Glu Ala Ile Glu Ile Trp 70 75 80 85 gcc gac cgc aag acc caa ggc ttc cac atc aaa gaa gac att aaa gcg 403 Ala Asp Arg Lys Thr Gln Gly Phe His Ile Lys Glu Asp Ile Lys Ala 90 95 100 aag gcc ctc cag gca gcc cgt cgg gca gca gaa cac ggc gtt ggt ttc 451 Lys Ala Leu Gln Ala Ala Arg Arg Ala Ala Glu His Gly Val Gly Phe 105 110 115 atc cgc act cac gta gat gtc acc gat ccc acg ttt gct gga ttc gaa 499 Ile Arg Thr His Val Asp Val Thr Asp Pro Thr Phe Ala Gly Phe Glu 120 125 130 gca att gcg gag ctg cgc gat gaa gtc cgc gag tgg tgc gat atc cag 547 Ala Ile Ala Glu Leu Arg Asp Glu Val Arg Glu Trp Cys Asp Ile Gln 135 140 145 att gtc gcc ttc ccg caa aat ggc att tac gcc tac gaa ggt ggc cag 595 Ile Val Ala Phe Pro Gln Asn Gly Ile Tyr Ala Tyr Glu Gly Gly Gln 150 155 160 165 aag cta atc tca gat gca atg tct gca ggt gca gat gtc gtt ggt ggc 643 Lys Leu Ile Ser Asp Ala Met Ser Ala Gly Ala Asp Val Val Gly Gly 170 175 180 atc cca cac ctt gaa ccc acc cga gac gat ggc gtc gag tcg gtg aaa 691 Ile Pro His Leu Glu Pro Thr Arg Asp Asp Gly Val Glu Ser Val Lys 185 190 195 tgg ctg ttc gac ctt gca gag aag cac tca gcc ccc atc gat atc cac 739 Trp Leu Phe Asp Leu Ala Glu Lys His Ser Ala Pro Ile Asp Ile His 200 205 210 act gat gaa att gac gat cca cat tcc cga ttt gtc gaa gtc ctc gcc 787 Thr Asp Glu Ile Asp Asp Pro His Ser Arg Phe Val Glu Val Leu Ala 215 220 225 gca gaa gcc gca aaa cgt gac atg ggc gca caa acc gtg gtg tct cat 835 Ala Glu Ala Ala Lys Arg Asp Met Gly Ala Gln Thr Val Val Ser His 230 235 240 245 tct gtg gcg atg gcc tat tac tca cct ggc tac atg gcg cga ctt tta 883 Ser Val Ala Met Ala Tyr Tyr Ser Pro Gly Tyr Met Ala Arg Leu Leu 250 255 260 ccc aag ctc gca gca tca aag gtt cgt ttt gca gta tgc ccc aat gaa 931 Pro Lys Leu Ala Ala Ser Lys Val Arg Phe Ala Val Cys Pro Asn Glu 265 270 275 aac ctc cat ctg caa gga ctt ggt ttc caa gga ccc gtc ccc cga ggt 979 Asn Leu His Leu Gln Gly Leu Gly Phe Gln Gly Pro Val Pro Arg Gly 280 285 290 gtt gca ccg gta aag caa ctt acc gaa tgg gga att cca gta agt ttt 1027 Val Ala Pro Val Lys Gln Leu Thr Glu Trp Gly Ile Pro Val Ser Phe 295 300 305 tgc cag gac tca ctc aat gac ccc ttc tac ccc atg ggc gat gga gat 1075 Cys Gln Asp Ser Leu Asn Asp Pro Phe Tyr Pro Met Gly Asp Gly Asp 310 315 320 325 cta ctc cgc att ctc gat tct gga tta cac gtg tcc cac atg ctc aca 1123 Leu Leu Arg Ile Leu Asp Ser Gly Leu His Val Ser His Met Leu Thr 330 335 340 gcc agc cac ttg aag aat gca cta tcg ttc atc acc acc aat cca gcc 1171 Ala Ser His Leu Lys Asn Ala Leu Ser Phe Ile Thr Thr Asn Pro Ala 345 350 355 gga aac cta ggc ctg gac aat tac gac att gca gaa aac tcc ccg gcg 1219 Gly Asn Leu Gly Leu Asp Asn Tyr Asp Ile Ala Glu Asn Ser Pro Ala 360 365 370 aac ctg ctg gtt ctt gat gcg agc agc gag aag gaa gct gta cag aga 1267 Asn Leu Leu Val Leu Asp Ala Ser Ser Glu Lys Glu Ala Val Gln Arg 375 380 385 aaa gct tcc gta ctt ttg agc atc cac cgc ggc aaa aag gtg ctc tcc 1315 Lys Ala Ser Val Leu Leu Ser Ile His Arg Gly Lys Lys Val Leu Ser 390 395 400 405 agg gag ccc gaa cag gtg gac tgg aac atc taacagccca gttgggcctc 1365 Arg Glu Pro Glu Gln Val Asp Trp Asn Ile 410 415 ctt 1368 <210> 1008 <211> 415 <212> PRT <213> Corynebacterium glutamicum <400> 1008 Val Arg Ile Thr Asn Ala Gln Val Lys Asn Tyr Ala Glu Leu Val Asp 1 5 10 15 Ile Thr Ile Glu Gly Glu Lys Ile Ser Ser Ile Thr Pro Ser Ser Ile 20 25 30 Arg Ser Glu Glu Asp His Arg Ala Asp Asp Tyr Asp Ala Ala Gly Arg 35 40 45 Leu Val Ala Pro Gln Phe Ala Glu Ala His Ile His Leu Asp Tyr Ala 50 55 60 Asn Thr Ala Gly Ile Pro Arg Glu Asn Ser Ser Gly Thr Leu Phe Glu 65 70 75 80 Ala Ile Glu Ile Trp Ala Asp Arg Lys Thr Gln Gly Phe His Ile Lys 85 90 95 Glu Asp Ile Lys Ala Lys Ala Leu Gln Ala Ala Arg Arg Ala Ala Glu 100 105 110 His Gly Val Gly Phe Ile Arg Thr His Val Asp Val Thr Asp Pro Thr 115 120 125 Phe Ala Gly Phe Glu Ala Ile Ala Glu Leu Arg Asp Glu Val Arg Glu 130 135 140 Trp Cys Asp Ile Gln Ile Val Ala Phe Pro Gln Asn Gly Ile Tyr Ala 145 150 155 160 Tyr Glu Gly Gly Gln Lys Leu Ile Ser Asp Ala Met Ser Ala Gly Ala 165 170 175 Asp Val Val Gly Gly Ile Pro His Leu Glu Pro Thr Arg Asp Asp Gly 180 185 190 Val Glu Ser Val Lys Trp Leu Phe Asp Leu Ala Glu Lys His Ser Ala 195 200 205 Pro Ile Asp Ile His Thr Asp Glu Ile Asp Asp Pro His Ser Arg Phe 210 215 220 Val Glu Val Leu Ala Ala Glu Ala Ala Lys Arg Asp Met Gly Ala Gln 225 230 235 240 Thr Val Val Ser His Ser Val Ala Met Ala Tyr Tyr Ser Pro Gly Tyr 245 250 255 Met Ala Arg Leu Leu Pro Lys Leu Ala Ala Ser Lys Val Arg Phe Ala 260 265 270 Val Cys Pro Asn Glu Asn Leu His Leu Gln Gly Leu Gly Phe Gln Gly 275 280 285 Pro Val Pro Arg Gly Val Ala Pro Val Lys Gln Leu Thr Glu Trp Gly 290 295 300 Ile Pro Val Ser Phe Cys Gln Asp Ser Leu Asn Asp Pro Phe Tyr Pro 305 310 315 320 Met Gly Asp Gly Asp Leu Leu Arg Ile Leu Asp Ser Gly Leu His Val 325 330 335 Ser His Met Leu Thr Ala Ser His Leu Lys Asn Ala Leu Ser Phe Ile 340 345 350 Thr Thr Asn Pro Ala Gly Asn Leu Gly Leu Asp Asn Tyr Asp Ile Ala 355 360 365 Glu Asn Ser Pro Ala Asn Leu Leu Val Leu Asp Ala Ser Ser Glu Lys 370 375 380 Glu Ala Val Gln Arg Lys Ala Ser Val Leu Leu Ser Ile His Arg Gly 385 390 395 400 Lys Lys Val Leu Ser Arg Glu Pro Glu Gln Val Asp Trp Asn Ile 405 410 415 <210> 1009 <211> 1368 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1345) <223> FRXA02272 <400> 1009 tatttaactc cacactaata cctgtcaagc aatagaatag atagcatctg gatcctccag 60 agtttgaaaa tatgccttga catgtagaaa tggagttctt gtg cgc att aca aac 115 Val Arg Ile Thr Asn 1 5 gcc cag gtt aag aac tac gca gag tta gtt gat atc acc ata gag ggt 163 Ala Gln Val Lys Asn Tyr Ala Glu Leu Val Asp Ile Thr Ile Glu Gly 10 15 20 gaa aaa att tcc tcg att acc ccc tct tca att cga tca gaa gaa gat 211 Glu Lys Ile Ser Ser Ile Thr Pro Ser Ser Ile Arg Ser Glu Glu Asp 25 30 35 cac cgc gcg gac gat tac gat gcc gca gga aga ctg gtc gca ccc cag 259 His Arg Ala Asp Asp Tyr Asp Ala Ala Gly Arg Leu Val Ala Pro Gln 40 45 50 ttc gcc gaa gca cac atc cac ctt gac tac gca aac acc gct gga atc 307 Phe Ala Glu Ala His Ile His Leu Asp Tyr Ala Asn Thr Ala Gly Ile 55 60 65 cct cgc gaa aac tct tcc ggc aca ctt ttt gaa gcc atc gaa atc tgg 355 Pro Arg Glu Asn Ser Ser Gly Thr Leu Phe Glu Ala Ile Glu Ile Trp 70 75 80 85 gcc gac cgc aag acc caa ggc ttc cac atc aaa gaa gac att aaa gcg 403 Ala Asp Arg Lys Thr Gln Gly Phe His Ile Lys Glu Asp Ile Lys Ala 90 95 100 aag gcc ctc cag gca gcc cgt cgg gca gca gaa cac ggc gtt ggt ttc 451 Lys Ala Leu Gln Ala Ala Arg Arg Ala Ala Glu His Gly Val Gly Phe 105 110 115 atc cgc act cac gta gat gtc acc gat ccc acg ttt gct gga ttc gaa 499 Ile Arg Thr His Val Asp Val Thr Asp Pro Thr Phe Ala Gly Phe Glu 120 125 130 gca att gcg gag ctg cgc gat gaa gtc cgc gag tgg tgc gat atc cag 547 Ala Ile Ala Glu Leu Arg Asp Glu Val Arg Glu Trp Cys Asp Ile Gln 135 140 145 att gtc gcc ttc ccg caa aat ggc att tac gcc tac gaa ggt ggc cag 595 Ile Val Ala Phe Pro Gln Asn Gly Ile Tyr Ala Tyr Glu Gly Gly Gln 150 155 160 165 aag cta atc tca gat gca atg tct gca ggt gca gat gtc gtt ggt ggc 643 Lys Leu Ile Ser Asp Ala Met Ser Ala Gly Ala Asp Val Val Gly Gly 170 175 180 atc cca cac ctt gaa ccc acc cga gac gat ggc gtc gag tcg gtg aaa 691 Ile Pro His Leu Glu Pro Thr Arg Asp Asp Gly Val Glu Ser Val Lys 185 190 195 tgg ctg ttc gac ctt gca gag aag cac tca gcc ccc atc gat atc cac 739 Trp Leu Phe Asp Leu Ala Glu Lys His Ser Ala Pro Ile Asp Ile His 200 205 210 act gat gaa att gac gat cca cat tcc cga ttt gtc gaa gtc ctc gcc 787 Thr Asp Glu Ile Asp Asp Pro His Ser Arg Phe Val Glu Val Leu Ala 215 220 225 gca gaa gcc gca aaa cgt gac atg ggc gca caa acc gtg gtg tct cat 835 Ala Glu Ala Ala Lys Arg Asp Met Gly Ala Gln Thr Val Val Ser His 230 235 240 245 tct gtg gcg atg gcc tat tac tca cct ggc tac atg gcg cga ctt tta 883 Ser Val Ala Met Ala Tyr Tyr Ser Pro Gly Tyr Met Ala Arg Leu Leu 250 255 260 ccc aag ctc gca gca tca aag gtt cgt ttt gca gta tgc ccc aat gaa 931 Pro Lys Leu Ala Ala Ser Lys Val Arg Phe Ala Val Cys Pro Asn Glu 265 270 275 aac ctc cat ctg caa gga ctt ggt ttc caa gga ccc gtc ccc cga ggt 979 Asn Leu His Leu Gln Gly Leu Gly Phe Gln Gly Pro Val Pro Arg Gly 280 285 290 gtt gca ccg gta aag caa ctt acc gaa tgg gga att cca gta agt ttt 1027 Val Ala Pro Val Lys Gln Leu Thr Glu Trp Gly Ile Pro Val Ser Phe 295 300 305 tgc cag gac tca ctc aat gac ccc ttc tac ccc atg ggc gat gga gat 1075 Cys Gln Asp Ser Leu Asn Asp Pro Phe Tyr Pro Met Gly Asp Gly Asp 310 315 320 325 cta ctc cgc att ctc gat tct gga tta cac gtg tcc cac atg ctc aca 1123 Leu Leu Arg Ile Leu Asp Ser Gly Leu His Val Ser His Met Leu Thr 330 335 340 gcc agc cac ttg aag aat gca cta tcg ttc atc acc acc aat cca gcc 1171 Ala Ser His Leu Lys Asn Ala Leu Ser Phe Ile Thr Thr Asn Pro Ala 345 350 355 gga aac cta ggc ctg gac aat tac gac att gca gaa aac tcc ccg gcg 1219 Gly Asn Leu Gly Leu Asp Asn Tyr Asp Ile Ala Glu Asn Ser Pro Ala 360 365 370 aac ctg ctg gtt ctt gat gcg agc agc gag aag gaa gct gta cag aga 1267 Asn Leu Leu Val Leu Asp Ala Ser Ser Glu Lys Glu Ala Val Gln Arg 375 380 385 aaa gct tcc gta ctt ttg agc atc cac cgc ggc aaa aag gtg ctc tcc 1315 Lys Ala Ser Val Leu Leu Ser Ile His Arg Gly Lys Lys Val Leu Ser 390 395 400 405 agg gag ccc gaa cag gtg gac tgg aac atc taacagccca gttgggcctc 1365 Arg Glu Pro Glu Gln Val Asp Trp Asn Ile 410 415 ctt 1368 <210> 1010 <211> 415 <212> PRT <213> Corynebacterium glutamicum <400> 1010 Val Arg Ile Thr Asn Ala Gln Val Lys Asn Tyr Ala Glu Leu Val Asp 1 5 10 15 Ile Thr Ile Glu Gly Glu Lys Ile Ser Ser Ile Thr Pro Ser Ser Ile 20 25 30 Arg Ser Glu Glu Asp His Arg Ala Asp Asp Tyr Asp Ala Ala Gly Arg 35 40 45 Leu Val Ala Pro Gln Phe Ala Glu Ala His Ile His Leu Asp Tyr Ala 50 55 60 Asn Thr Ala Gly Ile Pro Arg Glu Asn Ser Ser Gly Thr Leu Phe Glu 65 70 75 80 Ala Ile Glu Ile Trp Ala Asp Arg Lys Thr Gln Gly Phe His Ile Lys 85 90 95 Glu Asp Ile Lys Ala Lys Ala Leu Gln Ala Ala Arg Arg Ala Ala Glu 100 105 110 His Gly Val Gly Phe Ile Arg Thr His Val Asp Val Thr Asp Pro Thr 115 120 125 Phe Ala Gly Phe Glu Ala Ile Ala Glu Leu Arg Asp Glu Val Arg Glu 130 135 140 Trp Cys Asp Ile Gln Ile Val Ala Phe Pro Gln Asn Gly Ile Tyr Ala 145 150 155 160 Tyr Glu Gly Gly Gln Lys Leu Ile Ser Asp Ala Met Ser Ala Gly Ala 165 170 175 Asp Val Val Gly Gly Ile Pro His Leu Glu Pro Thr Arg Asp Asp Gly 180 185 190 Val Glu Ser Val Lys Trp Leu Phe Asp Leu Ala Glu Lys His Ser Ala 195 200 205 Pro Ile Asp Ile His Thr Asp Glu Ile Asp Asp Pro His Ser Arg Phe 210 215 220 Val Glu Val Leu Ala Ala Glu Ala Ala Lys Arg Asp Met Gly Ala Gln 225 230 235 240 Thr Val Val Ser His Ser Val Ala Met Ala Tyr Tyr Ser Pro Gly Tyr 245 250 255 Met Ala Arg Leu Leu Pro Lys Leu Ala Ala Ser Lys Val Arg Phe Ala 260 265 270 Val Cys Pro Asn Glu Asn Leu His Leu Gln Gly Leu Gly Phe Gln Gly 275 280 285 Pro Val Pro Arg Gly Val Ala Pro Val Lys Gln Leu Thr Glu Trp Gly 290 295 300 Ile Pro Val Ser Phe Cys Gln Asp Ser Leu Asn Asp Pro Phe Tyr Pro 305 310 315 320 Met Gly Asp Gly Asp Leu Leu Arg Ile Leu Asp Ser Gly Leu His Val 325 330 335 Ser His Met Leu Thr Ala Ser His Leu Lys Asn Ala Leu Ser Phe Ile 340 345 350 Thr Thr Asn Pro Ala Gly Asn Leu Gly Leu Asp Asn Tyr Asp Ile Ala 355 360 365 Glu Asn Ser Pro Ala Asn Leu Leu Val Leu Asp Ala Ser Ser Glu Lys 370 375 380 Glu Ala Val Gln Arg Lys Ala Ser Val Leu Leu Ser Ile His Arg Gly 385 390 395 400 Lys Lys Val Leu Ser Arg Glu Pro Glu Gln Val Asp Trp Asn Ile 405 410 415 <210> 1011 <211> 580 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(580) <223> RXN03004 <400> 1011 gctagcacga taaaaatcag cgccagcacc acgcgcccca ggaacctcat cgcagcaacc 60 cgtggcccaa ccctgaacgc tgaacgctac actggttgac gtg ctt ctt tca gat 115 Val Leu Leu Ser Asp 1 5 cgt gac att cgt aaa tca att gac gca ggc gac ttg gga att gaa cct 163 Arg Asp Ile Arg Lys Ser Ile Asp Ala Gly Asp Leu Gly Ile Glu Pro 10 15 20 ttc gac gct gag ctg att cag ccg tcg agt gtc gat gtc cgc atg gac 211 Phe Asp Ala Glu Leu Ile Gln Pro Ser Ser Val Asp Val Arg Met Asp 25 30 35 cgc tac ttc cgg gtt ttc aat aac tct aag tac acc cac att gac cct 259 Arg Tyr Phe Arg Val Phe Asn Asn Ser Lys Tyr Thr His Ile Asp Pro 40 45 50 aag ttg aat cag gat gag ctg acc agc ctt gtt gag gtt gag gac ggc 307 Lys Leu Asn Gln Asp Glu Leu Thr Ser Leu Val Glu Val Glu Asp Gly 55 60 65 gag ggc ttt gtg ctg cat ccg ggt gag ttt gtg ctg gcg tcc acg ctg 355 Glu Gly Phe Val Leu His Pro Gly Glu Phe Val Leu Ala Ser Thr Leu 70 75 80 85 gaa aag ttc act ttg cct gcg cat ctg gct ggt cgt ttg gag ggt aag 403 Glu Lys Phe Thr Leu Pro Ala His Leu Ala Gly Arg Leu Glu Gly Lys 90 95 100 tcg tct ctt ggt cgt ctt ggc ttg ttg acg cac tct act gct ggt ttc 451 Ser Ser Leu Gly Arg Leu Gly Leu Leu Thr His Ser Thr Ala Gly Phe 105 110 115 att gat cct ggt ttt agt ggt tac atc acg ttg gag ttg tcc aat gtg 499 Ile Asp Pro Gly Phe Ser Gly Tyr Ile Thr Leu Glu Leu Ser Asn Val 120 125 130 gct aat ctg ccg atc acg ttg tgg ccg ggt atg aag gtg ggg cag ctg 547 Ala Asn Leu Pro Ile Thr Leu Trp Pro Gly Met Lys Val Gly Gln Leu 135 140 145 gct ttg ttc cag atg agt tcc cct gcg gag act 580 Ala Leu Phe Gln Met Ser Ser Pro Ala Glu Thr 150 155 160 <210> 1012 <211> 160 <212> PRT <213> Corynebacterium glutamicum <400> 1012 Val Leu Leu Ser Asp Arg Asp Ile Arg Lys Ser Ile Asp Ala Gly Asp 1 5 10 15 Leu Gly Ile Glu Pro Phe Asp Ala Glu Leu Ile Gln Pro Ser Ser Val 20 25 30 Asp Val Arg Met Asp Arg Tyr Phe Arg Val Phe Asn Asn Ser Lys Tyr 35 40 45 Thr His Ile Asp Pro Lys Leu Asn Gln Asp Glu Leu Thr Ser Leu Val 50 55 60 Glu Val Glu Asp Gly Glu Gly Phe Val Leu His Pro Gly Glu Phe Val 65 70 75 80 Leu Ala Ser Thr Leu Glu Lys Phe Thr Leu Pro Ala His Leu Ala Gly 85 90 95 Arg Leu Glu Gly Lys Ser Ser Leu Gly Arg Leu Gly Leu Leu Thr His 100 105 110 Ser Thr Ala Gly Phe Ile Asp Pro Gly Phe Ser Gly Tyr Ile Thr Leu 115 120 125 Glu Leu Ser Asn Val Ala Asn Leu Pro Ile Thr Leu Trp Pro Gly Met 130 135 140 Lys Val Gly Gln Leu Ala Leu Phe Gln Met Ser Ser Pro Ala Glu Thr 145 150 155 160 <210> 1013 <211> 225 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(202) <223> RXN03137 <400> 1013 cggcgagttc atttggactg gcggcgactg ccacatttat gacaaccaca aggaacaggt 60 cgcggagcag ctgagccgat aagctcgccc ctaccccacc ttg gag ctc aac aag 115 Leu Glu Leu Asn Lys 1 5 gca gcg tac atg ttt gag tac agc ttc gat gac atc acc gtg tcc ggc 163 Ala Ala Tyr Met Phe Glu Tyr Ser Phe Asp Asp Ile Thr Val Ser Gly 10 15 20 tac gat cca cac cca ttg atc cgc ggc aag gtc gcc gta tgatcggtgc 212 Tyr Asp Pro His Pro Leu Ile Arg Gly Lys Val Ala Val 25 30 gatttgggca caa 225 <210> 1014 <211> 34 <212> PRT <213> Corynebacterium glutamicum <400> 1014 Leu Glu Leu Asn Lys Ala Ala Tyr Met Phe Glu Tyr Ser Phe Asp Asp 1 5 10 15 Ile Thr Val Ser Gly Tyr Asp Pro His Pro Leu Ile Arg Gly Lys Val 20 25 30 Ala Val <210> 1015 <211> 613 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> RXN03171 <400> 1015 atactttgtt ggactggaaa agtggccgtt tggttccctc caagcccaaa ttcgcccgcg 60 cggtcttctt ctgggcggca atgatttaac atgtgaagct atg gac atc acc atc 115 Met Asp Ile Thr Ile 1 5 gtc aac cac cca ctc gtt gct agc cgc cta acc ctg ttg cgc gac gag 163 Val Asn His Pro Leu Val Ala Ser Arg Leu Thr Leu Leu Arg Asp Glu 10 15 20 cgc agc gac aac gca gct ttc cgt gca gca gcc aac gac ctc ggc gcc 211 Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala Asn Asp Leu Gly Ala 25 30 35 atg ctg atc tac gaa gca tcc cga gat ctg gaa gtc gaa cac ttc gac 259 Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu Val Glu His Phe Asp 40 45 50 acc aaa acc ccc gtt gcc atg gct gaa ggt act cgc ctg aag cag cca 307 Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr Arg Leu Lys Gln Pro 55 60 65 ccc atc atc gtt ccc atc atc cgt gca ggt ctc ggc atg atc gac cca 355 Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu Gly Met Ile Asp Pro 70 75 80 85 gcg ctg tcg atg att ccg gat gca cag gtc ggc ttc att ggc ctt gcc 403 Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly Phe Ile Gly Leu Ala 90 95 100 cgc gat gag gaa acc cat gag cca gtc cca tac ctt gag gcg ctg cca 451 Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr Leu Glu Ala Leu Pro 105 110 115 cag gat cta agc aac cag cct gta ttc ctt gtc gat ccc atg ctg gcc 499 Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val Asp Pro Met Leu Ala 120 125 130 acc ggc ggt tcc ctc ctg cac gcg atc cgc ctt ctt gct gat cgt ggc 547 Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu Leu Ala Asp Arg Gly 135 140 145 gcc acc gac atc acc gcc atc tgc atg gtt tct gcg cag cca ggt gtg 595 Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser Ala Gln Pro Gly Val 150 155 160 165 gac gca ttg gcg gaa tct 613 Asp Ala Leu Ala Glu Ser 170 <210> 1016 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 1016 Met Asp Ile Thr Ile Val Asn His Pro Leu Val Ala Ser Arg Leu Thr 1 5 10 15 Leu Leu Arg Asp Glu Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala 20 25 30 Asn Asp Leu Gly Ala Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu 35 40 45 Val Glu His Phe Asp Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr 50 55 60 Arg Leu Lys Gln Pro Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu 65 70 75 80 Gly Met Ile Asp Pro Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly 85 90 95 Phe Ile Gly Leu Ala Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr 100 105 110 Leu Glu Ala Leu Pro Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val 115 120 125 Asp Pro Met Leu Ala Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu 130 135 140 Leu Ala Asp Arg Gly Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser 145 150 155 160 Ala Gln Pro Gly Val Asp Ala Leu Ala Glu Ser 165 170 <210> 1017 <211> 613 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> FRXA02857 <400> 1017 atactttgtt ggactggaaa agtggccgtt tggttccctc caagcccaaa ttcgcccgcg 60 cggtcttctt ctgggcggca atgatttaac atgtgaagct atg gac atc acc atc 115 Met Asp Ile Thr Ile 1 5 gtc aac cac cca ctc gtt gct agc cgc cta acc ctg ttg cgc gac gag 163 Val Asn His Pro Leu Val Ala Ser Arg Leu Thr Leu Leu Arg Asp Glu 10 15 20 cgc agc gac aac gca gct ttc cgt gca gca gcc aac gac ctc ggc gcc 211 Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala Asn Asp Leu Gly Ala 25 30 35 atg ctg atc tac gaa gca tcc cga gat ctg gaa gtc gaa cac ttc gac 259 Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu Val Glu His Phe Asp 40 45 50 acc aaa acc ccc gtt gcc atg gct gaa ggt act cgc ctg aag cag cca 307 Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr Arg Leu Lys Gln Pro 55 60 65 ccc atc atc gtt ccc atc atc cgt gca ggt ctc ggc atg atc gac cca 355 Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu Gly Met Ile Asp Pro 70 75 80 85 gcg ctg tcg atg att ccg gat gca cag gtc ggc ttc att ggc ctt gcc 403 Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly Phe Ile Gly Leu Ala 90 95 100 cgc gat gag gaa acc cat gag cca gtc cca tac ctt gag gcg ctg cca 451 Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr Leu Glu Ala Leu Pro 105 110 115 cag gat cta agc aac cag cct gta ttc ctt gtc gat ccc atg ctg gcc 499 Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val Asp Pro Met Leu Ala 120 125 130 acc ggc ggt tcc ctc ctg cac gcg atc cgc ctt ctt gct gat cgt ggc 547 Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu Leu Ala Asp Arg Gly 135 140 145 gcc acc gac atc acc gcc atc tgc atg gtt tct gcg cag cca ggt gtg 595 Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser Ala Gln Pro Gly Val 150 155 160 165 gac gca ttg gcg gaa tct 613 Asp Ala Leu Ala Glu Ser 170 <210> 1018 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 1018 Met Asp Ile Thr Ile Val Asn His Pro Leu Val Ala Ser Arg Leu Thr 1 5 10 15 Leu Leu Arg Asp Glu Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala 20 25 30 Asn Asp Leu Gly Ala Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu 35 40 45 Val Glu His Phe Asp Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr 50 55 60 Arg Leu Lys Gln Pro Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu 65 70 75 80 Gly Met Ile Asp Pro Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly 85 90 95 Phe Ile Gly Leu Ala Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr 100 105 110 Leu Glu Ala Leu Pro Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val 115 120 125 Asp Pro Met Leu Ala Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu 130 135 140 Leu Ala Asp Arg Gly Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser 145 150 155 160 Ala Gln Pro Gly Val Asp Ala Leu Ala Glu Ser 165 170 <210> 1019 <211> 678 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(655) <223> RXA02771 <400> 1019 gtttgtgata gatcgcacag tcggtaacgt tgttgttaat acagacctag ccggtatcgg 60 atggaacatg gaccgttggt ccagaagtga ggaataagta gtg agc gaa caa gct 115 Val Ser Glu Gln Ala 1 5 cta agc acc ttc gac agg gca cgt gag gcc ctg gac aag aaa acc cga 163 Leu Ser Thr Phe Asp Arg Ala Arg Glu Ala Leu Asp Lys Lys Thr Arg 10 15 20 tat gtg cag gat ttc cca gaa aaa ggt gtg ctt ttt gaa gac ctc acc 211 Tyr Val Gln Asp Phe Pro Glu Lys Gly Val Leu Phe Glu Asp Leu Thr 25 30 35 ccg gtg ttg ggc gat gca gaa tca ttt gtg gcc gtg gtg gac gcc atg 259 Pro Val Leu Gly Asp Ala Glu Ser Phe Val Ala Val Val Asp Ala Met 40 45 50 gct gaa gct gca gaa aaa ctg aat gca gaa atc atc ggt ggc ttg gat 307 Ala Glu Ala Ala Glu Lys Leu Asn Ala Glu Ile Ile Gly Gly Leu Asp 55 60 65 gcg cga gga ttc ctc ctc gga tct gct gtc gct tac aaa ctc ggc cta 355 Ala Arg Gly Phe Leu Leu Gly Ser Ala Val Ala Tyr Lys Leu Gly Leu 70 75 80 85 ggt gtg ctg gct atc cgc aag aag gga aag ctc ccc cca cct gtg gtg 403 Gly Val Leu Ala Ile Arg Lys Lys Gly Lys Leu Pro Pro Pro Val Val 90 95 100 acc cag gag tat gaa ctt gaa tac ggc act gca gca ctc gag ctg ccc 451 Thr Gln Glu Tyr Glu Leu Glu Tyr Gly Thr Ala Ala Leu Glu Leu Pro 105 110 115 agt gaa gga atc gac att gct ggt aaa aac atc gtt ttg atc gac gat 499 Ser Glu Gly Ile Asp Ile Ala Gly Lys Asn Ile Val Leu Ile Asp Asp 120 125 130 gtg ctg gca acc ggc ggc acc ttg ggc gct gca cgt aaa cta att gaa 547 Val Leu Ala Thr Gly Gly Thr Leu Gly Ala Ala Arg Lys Leu Ile Glu 135 140 145 tcg tgt gac gga cat gtt tcc gga tat gtt ctt gcc att gag gtc cca 595 Ser Cys Asp Gly His Val Ser Gly Tyr Val Leu Ala Ile Glu Val Pro 150 155 160 165 ggc ctc ggc ggt agg gat aat ctt ggt gat agg ccc gtc att gtg gtc 643 Gly Leu Gly Gly Arg Asp Asn Leu Gly Asp Arg Pro Val Ile Val Val 170 175 180 aga gat cct cag tagaaggatc gaaagaaagg cgg 678 Arg Asp Pro Gln 185 <210> 1020 <211> 185 <212> PRT <213> Corynebacterium glutamicum <400> 1020 Val Ser Glu Gln Ala Leu Ser Thr Phe Asp Arg Ala Arg Glu Ala Leu 1 5 10 15 Asp Lys Lys Thr Arg Tyr Val Gln Asp Phe Pro Glu Lys Gly Val Leu 20 25 30 Phe Glu Asp Leu Thr Pro Val Leu Gly Asp Ala Glu Ser Phe Val Ala 35 40 45 Val Val Asp Ala Met Ala Glu Ala Ala Glu Lys Leu Asn Ala Glu Ile 50 55 60 Ile Gly Gly Leu Asp Ala Arg Gly Phe Leu Leu Gly Ser Ala Val Ala 65 70 75 80 Tyr Lys Leu Gly Leu Gly Val Leu Ala Ile Arg Lys Lys Gly Lys Leu 85 90 95 Pro Pro Pro Val Val Thr Gln Glu Tyr Glu Leu Glu Tyr Gly Thr Ala 100 105 110 Ala Leu Glu Leu Pro Ser Glu Gly Ile Asp Ile Ala Gly Lys Asn Ile 115 120 125 Val Leu Ile Asp Asp Val Leu Ala Thr Gly Gly Thr Leu Gly Ala Ala 130 135 140 Arg Lys Leu Ile Glu Ser Cys Asp Gly His Val Ser Gly Tyr Val Leu 145 150 155 160 Ala Ile Glu Val Pro Gly Leu Gly Gly Arg Asp Asn Leu Gly Asp Arg 165 170 175 Pro Val Ile Val Val Arg Asp Pro Gln 180 185 <210> 1021 <211> 723 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(700) <223> RXA01512 <400> 1021 gggtaaaagc gataatggaa ggttggaagt ggtgcggcaa agtggcaagc ttaagatcac 60 tgattgacac ctgaatctac aacacaaggg gaacgcgacg atg agc aac aac gta 115 Met Ser Asn Asn Val 1 5 gaa atg gcc gac cac aaa gat ctc aat gtt cca gcc aac cca tac ggc 163 Glu Met Ala Asp His Lys Asp Leu Asn Val Pro Ala Asn Pro Tyr Gly 10 15 20 acc gac att gaa tca gta ttg atc agc gaa gag aag ctc aag cag cgc 211 Thr Asp Ile Glu Ser Val Leu Ile Ser Glu Glu Lys Leu Lys Gln Arg 25 30 35 atc gcc gaa atg gcc aag cgc gtc tcc gaa gag ttc aaa gac gcc gaa 259 Ile Ala Glu Met Ala Lys Arg Val Ser Glu Glu Phe Lys Asp Ala Glu 40 45 50 gaa gac ctc atc ctg gtg tgc gtg ctc aag ggc gcg ttc tac ttc ctg 307 Glu Asp Leu Ile Leu Val Cys Val Leu Lys Gly Ala Phe Tyr Phe Leu 55 60 65 gca gat ttc tcc cgc atg ctc gac atc ccc acc cag tcc gag ttc atg 355 Ala Asp Phe Ser Arg Met Leu Asp Ile Pro Thr Gln Ser Glu Phe Met 70 75 80 85 gcg gtg tcc tct tac gga aac tcc acc tcc tct tca ggc gtg gtg cgc 403 Ala Val Ser Ser Tyr Gly Asn Ser Thr Ser Ser Ser Gly Val Val Arg 90 95 100 atc ctc aag gac ctg gac aag gaa att gaa ggc cgc gac gtt ttg atc 451 Ile Leu Lys Asp Leu Asp Lys Glu Ile Glu Gly Arg Asp Val Leu Ile 105 110 115 gtg gaa gac atc atc gat tcc gga ctg acc ctg tcc tgg ctg atg cgc 499 Val Glu Asp Ile Ile Asp Ser Gly Leu Thr Leu Ser Trp Leu Met Arg 120 125 130 aac ctg aaa aac cgc aac cct aag tcc ctc aac gtg atc acc ttg ctg 547 Asn Leu Lys Asn Arg Asn Pro Lys Ser Leu Asn Val Ile Thr Leu Leu 135 140 145 cgt aag cca gag cgc ctg acc acc aac atc gac atg ttc gac att gga 595 Arg Lys Pro Glu Arg Leu Thr Thr Asn Ile Asp Met Phe Asp Ile Gly 150 155 160 165 ttt gat att cca aat gag ttt gtt gtg ggc tac gga ctt gat ttc gca 643 Phe Asp Ile Pro Asn Glu Phe Val Val Gly Tyr Gly Leu Asp Phe Ala 170 175 180 gaa cgc tac cgc gac ctg cca tat gtg ggc acc ctc gag cct cac gtg 691 Glu Arg Tyr Arg Asp Leu Pro Tyr Val Gly Thr Leu Glu Pro His Val 185 190 195 tac tcc gac tagtaatcaa aagtgcgaaa gag 723 Tyr Ser Asp 200 <210> 1022 <211> 200 <212> PRT <213> Corynebacterium glutamicum <400> 1022 Met Ser Asn Asn Val Glu Met Ala Asp His Lys Asp Leu Asn Val Pro 1 5 10 15 Ala Asn Pro Tyr Gly Thr Asp Ile Glu Ser Val Leu Ile Ser Glu Glu 20 25 30 Lys Leu Lys Gln Arg Ile Ala Glu Met Ala Lys Arg Val Ser Glu Glu 35 40 45 Phe Lys Asp Ala Glu Glu Asp Leu Ile Leu Val Cys Val Leu Lys Gly 50 55 60 Ala Phe Tyr Phe Leu Ala Asp Phe Ser Arg Met Leu Asp Ile Pro Thr 65 70 75 80 Gln Ser Glu Phe Met Ala Val Ser Ser Tyr Gly Asn Ser Thr Ser Ser 85 90 95 Ser Gly Val Val Arg Ile Leu Lys Asp Leu Asp Lys Glu Ile Glu Gly 100 105 110 Arg Asp Val Leu Ile Val Glu Asp Ile Ile Asp Ser Gly Leu Thr Leu 115 120 125 Ser Trp Leu Met Arg Asn Leu Lys Asn Arg Asn Pro Lys Ser Leu Asn 130 135 140 Val Ile Thr Leu Leu Arg Lys Pro Glu Arg Leu Thr Thr Asn Ile Asp 145 150 155 160 Met Phe Asp Ile Gly Phe Asp Ile Pro Asn Glu Phe Val Val Gly Tyr 165 170 175 Gly Leu Asp Phe Ala Glu Arg Tyr Arg Asp Leu Pro Tyr Val Gly Thr 180 185 190 Leu Glu Pro His Val Tyr Ser Asp 195 200 <210> 1023 <211> 597 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(574) <223> RXA02031 <400> 1023 tgcttgggcg ttaacgattc tatatatact tccctagaaa tcaagtgagc attcatctca 60 ttgcagaacg ttgaagcatc attgactagg atatgtagac atg aca gag gaa cgc 115 Met Thr Glu Glu Arg 1 5 gag att ctg acc tat gag atg ttc gga aca gca atg cgg gag ctg gcc 163 Glu Ile Leu Thr Tyr Glu Met Phe Gly Thr Ala Met Arg Glu Leu Ala 10 15 20 caa gaa att att gat gac tac cag cca gat tgc gtg ctg tcc att gcg 211 Gln Glu Ile Ile Asp Asp Tyr Gln Pro Asp Cys Val Leu Ser Ile Ala 25 30 35 cgt ggt ggt ctt cta atc ggt ggc gca ctt ggt tat gcg ctg ggt atc 259 Arg Gly Gly Leu Leu Ile Gly Gly Ala Leu Gly Tyr Ala Leu Gly Ile 40 45 50 aag aat gta tcg gtg atc aat gtg gag ttc tac acc gat att gga gag 307 Lys Asn Val Ser Val Ile Asn Val Glu Phe Tyr Thr Asp Ile Gly Glu 55 60 65 cac ttg gag gag cca atg atg ctg cct cca act cca aaa gct gtt gat 355 His Leu Glu Glu Pro Met Met Leu Pro Pro Thr Pro Lys Ala Val Asp 70 75 80 85 ctc tcg gga atg cgt gtg ctc gtc gct gac gat gtc gcg gat acc gga 403 Leu Ser Gly Met Arg Val Leu Val Ala Asp Asp Val Ala Asp Thr Gly 90 95 100 aag act ctt gag ttg gtc agg gac ttc ctg ggt gac caa gtt gtc gaa 451 Lys Thr Leu Glu Leu Val Arg Asp Phe Leu Gly Asp Gln Val Val Glu 105 110 115 gtg cgc act gca gtg atc tat cac aag cca aac agt gtg ttt aag ccg 499 Val Arg Thr Ala Val Ile Tyr His Lys Pro Asn Ser Val Phe Lys Pro 120 125 130 gag tat gtg tgg cgt gag act gat aag tgg att aac ttc cca tgg tct 547 Glu Tyr Val Trp Arg Glu Thr Asp Lys Trp Ile Asn Phe Pro Trp Ser 135 140 145 acc ctg cct cca gtg gag cct tct aag taatttttca cccgtgaaag 594 Thr Leu Pro Pro Val Glu Pro Ser Lys 150 155 tgc 597 <210> 1024 <211> 158 <212> PRT <213> Corynebacterium glutamicum <400> 1024 Met Thr Glu Glu Arg Glu Ile Leu Thr Tyr Glu Met Phe Gly Thr Ala 1 5 10 15 Met Arg Glu Leu Ala Gln Glu Ile Ile Asp Asp Tyr Gln Pro Asp Cys 20 25 30 Val Leu Ser Ile Ala Arg Gly Gly Leu Leu Ile Gly Gly Ala Leu Gly 35 40 45 Tyr Ala Leu Gly Ile Lys Asn Val Ser Val Ile Asn Val Glu Phe Tyr 50 55 60 Thr Asp Ile Gly Glu His Leu Glu Glu Pro Met Met Leu Pro Pro Thr 65 70 75 80 Pro Lys Ala Val Asp Leu Ser Gly Met Arg Val Leu Val Ala Asp Asp 85 90 95 Val Ala Asp Thr Gly Lys Thr Leu Glu Leu Val Arg Asp Phe Leu Gly 100 105 110 Asp Gln Val Val Glu Val Arg Thr Ala Val Ile Tyr His Lys Pro Asn 115 120 125 Ser Val Phe Lys Pro Glu Tyr Val Trp Arg Glu Thr Asp Lys Trp Ile 130 135 140 Asn Phe Pro Trp Ser Thr Leu Pro Pro Val Glu Pro Ser Lys 145 150 155 <210> 1025 <211> 753 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(730) <223> RXA00981 <400> 1025 aaccaatggc tgggtactga tgtggtgatc agtgcccagt ttcttctttc tactagtgtc 60 ggatagaagt acccccagtc cagaatgaag gtcaccacca atg tca gag aat ttg 115 Met Ser Glu Asn Leu 1 5 cca gcg ccc gag aat ctc ctg gac gcc gag aga att cag atg atc aag 163 Pro Ala Pro Glu Asn Leu Leu Asp Ala Glu Arg Ile Gln Met Ile Lys 10 15 20 aac ttc cgc aac gaa tta acg ggg ttc atg ctc aac tac caa ttt ggc 211 Asn Phe Arg Asn Glu Leu Thr Gly Phe Met Leu Asn Tyr Gln Phe Gly 25 30 35 att gat gag atc ctg acc aag atc aac atc ctg aaa act gaa ttc agc 259 Ile Asp Glu Ile Leu Thr Lys Ile Asn Ile Leu Lys Thr Glu Phe Ser 40 45 50 cag ctg cac gaa tac gca cct atc gag cac gta tct tca cga ttg aag 307 Gln Leu His Glu Tyr Ala Pro Ile Glu His Val Ser Ser Arg Leu Lys 55 60 65 aca cca gaa agc atc gtc aaa aag gtc atc cga aaa gga gac gag ctc 355 Thr Pro Glu Ser Ile Val Lys Lys Val Ile Arg Lys Gly Asp Glu Leu 70 75 80 85 tcc ctc gca gct atc aaa gac aca gtg ttt gat atc gca ggc att cga 403 Ser Leu Ala Ala Ile Lys Asp Thr Val Phe Asp Ile Ala Gly Ile Arg 90 95 100 atc gtc tgc agt ttc ctc aaa gat gcc tac gca atc gcc gat atg ctg 451 Ile Val Cys Ser Phe Leu Lys Asp Ala Tyr Ala Ile Ala Asp Met Leu 105 110 115 acc aac caa aaa gac gtc acg gtc atc gag gcc aaa gac tac atc gct 499 Thr Asn Gln Lys Asp Val Thr Val Ile Glu Ala Lys Asp Tyr Ile Ala 120 125 130 aac cca aag ccg aac ggc tac aag agt ttg cac ctt atc ctc caa gtg 547 Asn Pro Lys Pro Asn Gly Tyr Lys Ser Leu His Leu Ile Leu Gln Val 135 140 145 cct gtc ttc ctg tct aac tcc gtg gaa aag gtc aat gtt gaa gtc cag 595 Pro Val Phe Leu Ser Asn Ser Val Glu Lys Val Asn Val Glu Val Gln 150 155 160 165 atc cgc acc att gcc atg gac ttc tgg gca agc ctc gag cac aaa atc 643 Ile Arg Thr Ile Ala Met Asp Phe Trp Ala Ser Leu Glu His Lys Ile 170 175 180 tac tac aaa ttt gaa caa gaa gtt cct cag tca atc ctt gat gag ctc 691 Tyr Tyr Lys Phe Glu Gln Glu Val Pro Gln Ser Ile Leu Asp Glu Leu 185 190 195 agt gaa gat gga aag aat cca cgg gga agt gaa gtc act taaacctcca 740 Ser Glu Asp Gly Lys Asn Pro Arg Gly Ser Glu Val Thr 200 205 210 gttgaaacca ctg 753 <210> 1026 <211> 210 <212> PRT <213> Corynebacterium glutamicum <400> 1026 Met Ser Glu Asn Leu Pro Ala Pro Glu Asn Leu Leu Asp Ala Glu Arg 1 5 10 15 Ile Gln Met Ile Lys Asn Phe Arg Asn Glu Leu Thr Gly Phe Met Leu 20 25 30 Asn Tyr Gln Phe Gly Ile Asp Glu Ile Leu Thr Lys Ile Asn Ile Leu 35 40 45 Lys Thr Glu Phe Ser Gln Leu His Glu Tyr Ala Pro Ile Glu His Val 50 55 60 Ser Ser Arg Leu Lys Thr Pro Glu Ser Ile Val Lys Lys Val Ile Arg 65 70 75 80 Lys Gly Asp Glu Leu Ser Leu Ala Ala Ile Lys Asp Thr Val Phe Asp 85 90 95 Ile Ala Gly Ile Arg Ile Val Cys Ser Phe Leu Lys Asp Ala Tyr Ala 100 105 110 Ile Ala Asp Met Leu Thr Asn Gln Lys Asp Val Thr Val Ile Glu Ala 115 120 125 Lys Asp Tyr Ile Ala Asn Pro Lys Pro Asn Gly Tyr Lys Ser Leu His 130 135 140 Leu Ile Leu Gln Val Pro Val Phe Leu Ser Asn Ser Val Glu Lys Val 145 150 155 160 Asn Val Glu Val Gln Ile Arg Thr Ile Ala Met Asp Phe Trp Ala Ser 165 170 175 Leu Glu His Lys Ile Tyr Tyr Lys Phe Glu Gln Glu Val Pro Gln Ser 180 185 190 Ile Leu Asp Glu Leu Ser Glu Asp Gly Lys Asn Pro Arg Gly Ser Glu 195 200 205 Val Thr 210 <210> 1027 <211> 1158 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1135) <223> RXN02772 <400> 1027 tgaggtccca ggcctcggcg gtagggataa tcttggtgat aggcccgtca ttgtggtcag 60 agatcctcag tagaaggatc gaaagaaagg cggcaggaaa atg agt ctg gag cgc 115 Met Ser Leu Glu Arg 1 5 aac aca caa aaa tct tcc atg ggt gtg cga agc atg tca gcc agg ctt 163 Asn Thr Gln Lys Ser Ser Met Gly Val Arg Ser Met Ser Ala Arg Leu 10 15 20 gcc cgc agc ctc aca gga aac cgc gtt cgc acc aac cct gtg ctg gat 211 Ala Arg Ser Leu Thr Gly Asn Arg Val Arg Thr Asn Pro Val Leu Asp 25 30 35 ccg ctg ctg agc atc cac cgg caa ttt cac cca cgc gcc gac gta caa 259 Pro Leu Leu Ser Ile His Arg Gln Phe His Pro Arg Ala Asp Val Gln 40 45 50 gtg ttg gaa cgt gca tat gac acc gcg gaa cgt ctt cat gat ggt gtg 307 Val Leu Glu Arg Ala Tyr Asp Thr Ala Glu Arg Leu His Asp Gly Val 55 60 65 att cga aaa tcg ggc gat ccg tat att acc cac ccg ttg gct gtc gcc 355 Ile Arg Lys Ser Gly Asp Pro Tyr Ile Thr His Pro Leu Ala Val Ala 70 75 80 85 acc atc gcc gcg gaa atc ggc atg gac acc acc acg ctc gtc gca gcc 403 Thr Ile Ala Ala Glu Ile Gly Met Asp Thr Thr Thr Leu Val Ala Ala 90 95 100 ttg ttg cat gac acg gtg gaa gac acc gac tac tct ttg gac gat ctc 451 Leu Leu His Asp Thr Val Glu Asp Thr Asp Tyr Ser Leu Asp Asp Leu 105 110 115 acc cga gat ttc gga gaa gaa gtt gcc agg ctt gtc gac ggt gtc acc 499 Thr Arg Asp Phe Gly Glu Glu Val Ala Arg Leu Val Asp Gly Val Thr 120 125 130 aag ctc gac aaa gtc gca cta ggt gct gcc gcg gag gcc gaa acg att 547 Lys Leu Asp Lys Val Ala Leu Gly Ala Ala Ala Glu Ala Glu Thr Ile 135 140 145 cgc aaa atg atc gtc gcc atg agc cag gac ccc cgc gtg ctg gtg att 595 Arg Lys Met Ile Val Ala Met Ser Gln Asp Pro Arg Val Leu Val Ile 150 155 160 165 aaa gtg gcc gac cgt ttg cac aat atg cgc acc atg cgg ttc ctg ccg 643 Lys Val Ala Asp Arg Leu His Asn Met Arg Thr Met Arg Phe Leu Pro 170 175 180 ccg gaa aag caa gct aaa aaa gca cgc caa acc ctt gaa gtg att gct 691 Pro Glu Lys Gln Ala Lys Lys Ala Arg Gln Thr Leu Glu Val Ile Ala 185 190 195 cct ttg gca cac cgc ctg ggc atg gcc agc gtg aaa tgg gaa ttg gaa 739 Pro Leu Ala His Arg Leu Gly Met Ala Ser Val Lys Trp Glu Leu Glu 200 205 210 gat cta tcc ttt gcc att ttg tac ccc aag aag tac gaa gag atc gtg 787 Asp Leu Ser Phe Ala Ile Leu Tyr Pro Lys Lys Tyr Glu Glu Ile Val 215 220 225 cgt ctt gtt gcc gac cgc gcg ccc tct aga gac cgg tac ctc aaa gaa 835 Arg Leu Val Ala Asp Arg Ala Pro Ser Arg Asp Arg Tyr Leu Lys Glu 230 235 240 245 att att gat caa gtc acc ggt ggc ttg cgc gaa aac aac atc gcg gca 883 Ile Ile Asp Gln Val Thr Gly Gly Leu Arg Glu Asn Asn Ile Ala Ala 250 255 260 gaa gtg ctt ggt cga cca aag cac tac tgg tct atc tat caa aag atg 931 Glu Val Leu Gly Arg Pro Lys His Tyr Trp Ser Ile Tyr Gln Lys Met 265 270 275 atc gtt cgc ggt cgt gat ttt gac gat att ttt gat ctt gtt ggc atc 979 Ile Val Arg Gly Arg Asp Phe Asp Asp Ile Phe Asp Leu Val Gly Ile 280 285 290 cgc atc ctg gta gac aac gtg aac aac tgt gta cgc cgc cat cgg tgt 1027 Arg Ile Leu Val Asp Asn Val Asn Asn Cys Val Arg Arg His Arg Cys 295 300 305 cgt gca ctc cct gtt caa tgc tct gcc tgg ccg att caa aga cta tat 1075 Arg Ala Leu Pro Val Gln Cys Ser Ala Trp Pro Ile Gln Arg Leu Tyr 310 315 320 325 ttc agc ccc gcg ctt cgg tgt cta cca atc cct gca cac cac cgt gat 1123 Phe Ser Pro Ala Leu Arg Cys Leu Pro Ile Pro Ala His His Arg Asp 330 335 340 ggg acc tgg cgg taagcctctg gaagttcagg cac 1158 Gly Thr Trp Arg 345 <210> 1028 <211> 345 <212> PRT <213> Corynebacterium glutamicum <400> 1028 Met Ser Leu Glu Arg Asn Thr Gln Lys Ser Ser Met Gly Val Arg Ser 1 5 10 15 Met Ser Ala Arg Leu Ala Arg Ser Leu Thr Gly Asn Arg Val Arg Thr 20 25 30 Asn Pro Val Leu Asp Pro Leu Leu Ser Ile His Arg Gln Phe His Pro 35 40 45 Arg Ala Asp Val Gln Val Leu Glu Arg Ala Tyr Asp Thr Ala Glu Arg 50 55 60 Leu His Asp Gly Val Ile Arg Lys Ser Gly Asp Pro Tyr Ile Thr His 65 70 75 80 Pro Leu Ala Val Ala Thr Ile Ala Ala Glu Ile Gly Met Asp Thr Thr 85 90 95 Thr Leu Val Ala Ala Leu Leu His Asp Thr Val Glu Asp Thr Asp Tyr 100 105 110 Ser Leu Asp Asp Leu Thr Arg Asp Phe Gly Glu Glu Val Ala Arg Leu 115 120 125 Val Asp Gly Val Thr Lys Leu Asp Lys Val Ala Leu Gly Ala Ala Ala 130 135 140 Glu Ala Glu Thr Ile Arg Lys Met Ile Val Ala Met Ser Gln Asp Pro 145 150 155 160 Arg Val Leu Val Ile Lys Val Ala Asp Arg Leu His Asn Met Arg Thr 165 170 175 Met Arg Phe Leu Pro Pro Glu Lys Gln Ala Lys Lys Ala Arg Gln Thr 180 185 190 Leu Glu Val Ile Ala Pro Leu Ala His Arg Leu Gly Met Ala Ser Val 195 200 205 Lys Trp Glu Leu Glu Asp Leu Ser Phe Ala Ile Leu Tyr Pro Lys Lys 210 215 220 Tyr Glu Glu Ile Val Arg Leu Val Ala Asp Arg Ala Pro Ser Arg Asp 225 230 235 240 Arg Tyr Leu Lys Glu Ile Ile Asp Gln Val Thr Gly Gly Leu Arg Glu 245 250 255 Asn Asn Ile Ala Ala Glu Val Leu Gly Arg Pro Lys His Tyr Trp Ser 260 265 270 Ile Tyr Gln Lys Met Ile Val Arg Gly Arg Asp Phe Asp Asp Ile Phe 275 280 285 Asp Leu Val Gly Ile Arg Ile Leu Val Asp Asn Val Asn Asn Cys Val 290 295 300 Arg Arg His Arg Cys Arg Ala Leu Pro Val Gln Cys Ser Ala Trp Pro 305 310 315 320 Ile Gln Arg Leu Tyr Phe Ser Pro Ala Leu Arg Cys Leu Pro Ile Pro 325 330 335 Ala His His Arg Asp Gly Thr Trp Arg 340 345 <210> 1029 <211> 903 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(880) <223> FRXA02772 <220> <221> misc_feature <222> 850, 853 <223> n = a, c, t, or g <400> 1029 cattgtggtc agagatcctc agtagaagga tcgaaagaaa ggcggcagga aaatgagtct 60 ggagcgcaac acacaaaaat cttccatggg tgtgcgaagc atg tca gcc agg ctt 115 Met Ser Ala Arg Leu 1 5 gcc cgc agc ctc aca gga aac cgc gtt cgc acc aac cct gtg ctg gat 163 Ala Arg Ser Leu Thr Gly Asn Arg Val Arg Thr Asn Pro Val Leu Asp 10 15 20 ccg ctg ctg agc atc cac cgg caa ttt cac cca cgc gcc gac gta caa 211 Pro Leu Leu Ser Ile His Arg Gln Phe His Pro Arg Ala Asp Val Gln 25 30 35 gtg ttg gaa cgt gca tat gac acc gcg gaa cgt ctt cat gat ggt gtg 259 Val Leu Glu Arg Ala Tyr Asp Thr Ala Glu Arg Leu His Asp Gly Val 40 45 50 att cga aaa tcg ggc gat ccg tat att acc cac ccg ttg gct gtc gcc 307 Ile Arg Lys Ser Gly Asp Pro Tyr Ile Thr His Pro Leu Ala Val Ala 55 60 65 acc atc gcc gcg gaa atc ggc atg gac acc acc acg ctc gtc gca gcc 355 Thr Ile Ala Ala Glu Ile Gly Met Asp Thr Thr Thr Leu Val Ala Ala 70 75 80 85 ttg ttg cat gac acg gtg gaa gac acc gac tac tct ttg gac gat ctc 403 Leu Leu His Asp Thr Val Glu Asp Thr Asp Tyr Ser Leu Asp Asp Leu 90 95 100 acc cga gat ttc gga gaa gaa gtt gcc agg ctt gtc gac ggt gtc acc 451 Thr Arg Asp Phe Gly Glu Glu Val Ala Arg Leu Val Asp Gly Val Thr 105 110 115 aag ctc gac aaa gtc gca cta ggt gct gcc gcg gag gcc gaa acg att 499 Lys Leu Asp Lys Val Ala Leu Gly Ala Ala Ala Glu Ala Glu Thr Ile 120 125 130 cgc aaa atg atc gtc gcc atg agc cag gac ccc cgc gtg ctg gtg att 547 Arg Lys Met Ile Val Ala Met Ser Gln Asp Pro Arg Val Leu Val Ile 135 140 145 aaa gtg gcc gac cgt ttg cac aat atg cgc acc atg cgg ttc ctg ccg 595 Lys Val Ala Asp Arg Leu His Asn Met Arg Thr Met Arg Phe Leu Pro 150 155 160 165 ccg gaa aag caa gct aaa aaa gca cgc caa acc ctt gaa gtg att gct 643 Pro Glu Lys Gln Ala Lys Lys Ala Arg Gln Thr Leu Glu Val Ile Ala 170 175 180 cct ttg gca cac cgc ctg ggc atg gcc agc gtg aaa tgg gaa ttg gaa 691 Pro Leu Ala His Arg Leu Gly Met Ala Ser Val Lys Trp Glu Leu Glu 185 190 195 gat cta tcc ttt gcc att ttg tac ccc aag aag tac gaa gag atc gtg 739 Asp Leu Ser Phe Ala Ile Leu Tyr Pro Lys Lys Tyr Glu Glu Ile Val 200 205 210 cgt ctt gtt gcc gac cgc gcg ccc tct aga gac cgg tac ctc aaa gaa 787 Arg Leu Val Ala Asp Arg Ala Pro Ser Arg Asp Arg Tyr Leu Lys Glu 215 220 225 att att gat caa gtc acc ggt ggc ttg cgc gaa aac aac atc gcg gca 835 Ile Ile Asp Gln Val Thr Gly Gly Leu Arg Glu Asn Asn Ile Ala Ala 230 235 240 245 gaa gtg ctt ggt cgn ccn aag cac tct ggt ctt tct ttc aaa aga 880 Glu Val Leu Gly Arg Pro Lys His Ser Gly Leu Ser Phe Lys Arg 250 255 260 tgatcgttcg cggtcgtgat ttt 903 <210> 1030 <211> 260 <212> PRT <213> Corynebacterium glutamicum <400> 1030 Met Ser Ala Arg Leu Ala Arg Ser Leu Thr Gly Asn Arg Val Arg Thr 1 5 10 15 Asn Pro Val Leu Asp Pro Leu Leu Ser Ile His Arg Gln Phe His Pro 20 25 30 Arg Ala Asp Val Gln Val Leu Glu Arg Ala Tyr Asp Thr Ala Glu Arg 35 40 45 Leu His Asp Gly Val Ile Arg Lys Ser Gly Asp Pro Tyr Ile Thr His 50 55 60 Pro Leu Ala Val Ala Thr Ile Ala Ala Glu Ile Gly Met Asp Thr Thr 65 70 75 80 Thr Leu Val Ala Ala Leu Leu His Asp Thr Val Glu Asp Thr Asp Tyr 85 90 95 Ser Leu Asp Asp Leu Thr Arg Asp Phe Gly Glu Glu Val Ala Arg Leu 100 105 110 Val Asp Gly Val Thr Lys Leu Asp Lys Val Ala Leu Gly Ala Ala Ala 115 120 125 Glu Ala Glu Thr Ile Arg Lys Met Ile Val Ala Met Ser Gln Asp Pro 130 135 140 Arg Val Leu Val Ile Lys Val Ala Asp Arg Leu His Asn Met Arg Thr 145 150 155 160 Met Arg Phe Leu Pro Pro Glu Lys Gln Ala Lys Lys Ala Arg Gln Thr 165 170 175 Leu Glu Val Ile Ala Pro Leu Ala His Arg Leu Gly Met Ala Ser Val 180 185 190 Lys Trp Glu Leu Glu Asp Leu Ser Phe Ala Ile Leu Tyr Pro Lys Lys 195 200 205 Tyr Glu Glu Ile Val Arg Leu Val Ala Asp Arg Ala Pro Ser Arg Asp 210 215 220 Arg Tyr Leu Lys Glu Ile Ile Asp Gln Val Thr Gly Gly Leu Arg Glu 225 230 235 240 Asn Asn Ile Ala Ala Glu Val Leu Gly Arg Pro Lys His Ser Gly Leu 245 250 255 Ser Phe Lys Arg 260 <210> 1031 <211> 262 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(262) <223> FRXA02773 <220> <221> misc_feature <222> 71, 74, 155, 162, 192, 214, 225, 230, 233 <223> n = a, c, t, or g <220> <221> VARIANT <222> 19 <223> Xaa = Phe, Leu, Ile, or Val <220> <221> VARIANT <222> 21 <223> Xaa = Val, Ala, Glu, or Gly <220> <221> VARIANT <222> 31 <223> Xaa = Leu, Pro, His, or Arg <220> <221> VARIANT <222> 42 <223> Xaa = Val, Ala, Asp, or Gly <220> <221> VARIANT <222> 44 <223> Xaa = Ser, Pro, Thr, or Ala <220> <221> VARIANT <222> 45 <223> Xaa = Phe, Leu, Ile, or Val <400> 1031 tcaaagaaat tattgatcaa gtcaccggtg gcttgcgcga aaacaacatc gcggcagaag 60 tgcttggtcg nccnaagcac tctggtcttt ctttcaaaag atg atc gtt cgc ggt 115 Met Ile Val Arg Gly 1 5 cgt gat ttt gac gat att ttt gat ctt gtt ggc atc cgc ntc ctg gna 163 Arg Asp Phe Asp Asp Ile Phe Asp Leu Val Gly Ile Arg Xaa Leu Xaa 10 15 20 gac aac gtg aac aac tgg gta cgc cgc cnt cgg tgt cgt gca ctc ccn 211 Asp Asn Val Asn Asn Trp Val Arg Arg Xaa Arg Cys Arg Ala Leu Pro 25 30 35 gtn caa tgc tct gnc tgg ncg ntt caa aga cta tat ttc agc ccc gcg 259 Val Gln Cys Ser Xaa Trp Xaa Xaa Gln Arg Leu Tyr Phe Ser Pro Ala 40 45 50 ctt 262 Leu <210> 1032 <211> 54 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 19 <223> Xaa = Phe, Leu, Ile, or Val <220> <221> VARIANT <222> 21 <223> Xaa = Val, Ala, Glu, or Gly <220> <221> VARIANT <222> 31 <223> Xaa = Leu, Pro, His, or Arg <220> <221> VARIANT <222> 42 <223> Xaa = Val, Ala, Asp, or Gly <220> <221> VARIANT <222> 44 <223> Xaa = Ser, Pro, Thr, or Ala <220> <221> VARIANT <222> 45 <223> Xaa = Phe, Leu, Ile, or Val <400> 1032 Met Ile Val Arg Gly Arg Asp Phe Asp Asp Ile Phe Asp Leu Val Gly 1 5 10 15 Ile Arg Xaa Leu Xaa Asp Asn Val Asn Asn Trp Val Arg Arg Xaa Arg 20 25 30 Cys Arg Ala Leu Pro Val Gln Cys Ser Xaa Trp Xaa Xaa Gln Arg Leu 35 40 45 Tyr Phe Ser Pro Ala Leu 50 <210> 1033 <211> 654 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(631) <223> RXA01835 <400> 1033 tcaacatcta ttcctcctgc gatttgcatg ggatatatat taaaaattct agccgaaagt 60 ttcctgcgtg aatacacttt ccccgcgcct tcgcaaagct atg aat act gcc gcg 115 Met Asn Thr Ala Ala 1 5 tgg gca cac cgc cac cac gta cgc aaa ggc ggt gga att ccg tat gtc 163 Trp Ala His Arg His His Val Arg Lys Gly Gly Gly Ile Pro Tyr Val 10 15 20 agc cat ctt tat tca gtg atg tac ttg ctg gcc agc gtc act aat gat 211 Ser His Leu Tyr Ser Val Met Tyr Leu Leu Ala Ser Val Thr Asn Asp 25 30 35 gaa gat gtg ctc atc gcc ggg ctg ctc cac gac acc ctc gaa gac gta 259 Glu Asp Val Leu Ile Ala Gly Leu Leu His Asp Thr Leu Glu Asp Val 40 45 50 ccc gag gaa tac aat tct gcc caa ctt gaa gct gat ttt ggt ccg cgg 307 Pro Glu Glu Tyr Asn Ser Ala Gln Leu Glu Ala Asp Phe Gly Pro Arg 55 60 65 gtg cgc gag ttg gtg gaa gag ctc acc aaa cag ccc tta aaa agc tgg 355 Val Arg Glu Leu Val Glu Glu Leu Thr Lys Gln Pro Leu Lys Ser Trp 70 75 80 85 aaa gcg cgt gcc gac gct tac ctc ctg cac ctc agc gca ggt gcc agc 403 Lys Ala Arg Ala Asp Ala Tyr Leu Leu His Leu Ser Ala Gly Ala Ser 90 95 100 tta gag gct gtc tta atc tcc acc gca gat aaa ctg cat aat ctc atg 451 Leu Glu Ala Val Leu Ile Ser Thr Ala Asp Lys Leu His Asn Leu Met 105 110 115 tcc atc ttg gat gac ctt gaa ata cac ggt gaa gat tta tgg caa cgc 499 Ser Ile Leu Asp Asp Leu Glu Ile His Gly Glu Asp Leu Trp Gln Arg 120 125 130 ttt aac gct ggc aaa gag cag caa atc tgg tgg tat agc gag gtt tat 547 Phe Asn Ala Gly Lys Glu Gln Gln Ile Trp Trp Tyr Ser Glu Val Tyr 135 140 145 cag ata tct ctc cag cgc tta ggg ttc aat gag ttg aat aaa caa ctg 595 Gln Ile Ser Leu Gln Arg Leu Gly Phe Asn Glu Leu Asn Lys Gln Leu 150 155 160 165 ggg ttg tgc gtc gaa aag ctc tta aag caa agc gcc taggcgctcg 641 Gly Leu Cys Val Glu Lys Leu Leu Lys Gln Ser Ala 170 175 gcggcgtcga taa 654 <210> 1034 <211> 177 <212> PRT <213> Corynebacterium glutamicum <400> 1034 Met Asn Thr Ala Ala Trp Ala His Arg His His Val Arg Lys Gly Gly 1 5 10 15 Gly Ile Pro Tyr Val Ser His Leu Tyr Ser Val Met Tyr Leu Leu Ala 20 25 30 Ser Val Thr Asn Asp Glu Asp Val Leu Ile Ala Gly Leu Leu His Asp 35 40 45 Thr Leu Glu Asp Val Pro Glu Glu Tyr Asn Ser Ala Gln Leu Glu Ala 50 55 60 Asp Phe Gly Pro Arg Val Arg Glu Leu Val Glu Glu Leu Thr Lys Gln 65 70 75 80 Pro Leu Lys Ser Trp Lys Ala Arg Ala Asp Ala Tyr Leu Leu His Leu 85 90 95 Ser Ala Gly Ala Ser Leu Glu Ala Val Leu Ile Ser Thr Ala Asp Lys 100 105 110 Leu His Asn Leu Met Ser Ile Leu Asp Asp Leu Glu Ile His Gly Glu 115 120 125 Asp Leu Trp Gln Arg Phe Asn Ala Gly Lys Glu Gln Gln Ile Trp Trp 130 135 140 Tyr Ser Glu Val Tyr Gln Ile Ser Leu Gln Arg Leu Gly Phe Asn Glu 145 150 155 160 Leu Asn Lys Gln Leu Gly Leu Cys Val Glu Lys Leu Leu Lys Gln Ser 165 170 175 Ala <210> 1035 <211> 1395 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1372) <223> RXA01483 <400> 1035 gggtgcccga taaggtgaag catctttgcg cgcaatccaa ggtctgctgc gcccttcgcg 60 gcgtgcacgc catgagcaac ttcggaggct gaaaaagtag atg tac ccc tat tcc 115 Met Tyr Pro Tyr Ser 1 5 gac gca gac gct ttt cga cgc cag cct gag cgc gcc aag tcc agc caa 163 Asp Ala Asp Ala Phe Arg Arg Gln Pro Glu Arg Ala Lys Ser Ser Gln 10 15 20 ctg cgt acc agc gcc gta gac acc cgc agc gcg ttc gcc cgc gac cgg 211 Leu Arg Thr Ser Ala Val Asp Thr Arg Ser Ala Phe Ala Arg Asp Arg 25 30 35 gct cgc gtg ctg cat tct gct gct ctt cga cgc ctc gcg gat aaa acc 259 Ala Arg Val Leu His Ser Ala Ala Leu Arg Arg Leu Ala Asp Lys Thr 40 45 50 caa gtg gtt ggc ccc aat gat ggt gat act ccg cgc acc cgg ctg acg 307 Gln Val Val Gly Pro Asn Asp Gly Asp Thr Pro Arg Thr Arg Leu Thr 55 60 65 cac tct ttg gaa gta gct caa att gca cgg gga atc gga gct gga ctg 355 His Ser Leu Glu Val Ala Gln Ile Ala Arg Gly Ile Gly Ala Gly Leu 70 75 80 85 gat ttg gat cct gat ctg tgc gat ctg gca ggg ctg tgc cat gac att 403 Asp Leu Asp Pro Asp Leu Cys Asp Leu Ala Gly Leu Cys His Asp Ile 90 95 100 ggg cat ccg ccg tat gga cac aac ggt gaa aac gcg ttg aat gaa gtt 451 Gly His Pro Pro Tyr Gly His Asn Gly Glu Asn Ala Leu Asn Glu Val 105 110 115 gct gcg gcc tgt gga gga ttt gag ggc aac gcc caa acc ttg cgt att 499 Ala Ala Ala Cys Gly Gly Phe Glu Gly Asn Ala Gln Thr Leu Arg Ile 120 125 130 ctc acg cgt ctg gag cca aaa att gtc tct gat gag ggg gag agc ttt 547 Leu Thr Arg Leu Glu Pro Lys Ile Val Ser Asp Glu Gly Glu Ser Phe 135 140 145 ggg ctg aac ttg tcg cgg gct gct ctt gat gct gca tgt aag tat ccg 595 Gly Leu Asn Leu Ser Arg Ala Ala Leu Asp Ala Ala Cys Lys Tyr Pro 150 155 160 165 tgg gct aaa aca aat gcg gat ggc agt gtc aat aag aaa tac agt gct 643 Trp Ala Lys Thr Asn Ala Asp Gly Ser Val Asn Lys Lys Tyr Ser Ala 170 175 180 tat gac gag gac gca gaa atc ctc gct tgg att aga caa ggc cat gag 691 Tyr Asp Glu Asp Ala Glu Ile Leu Ala Trp Ile Arg Gln Gly His Glu 185 190 195 gat ctt cgc cca ccg atc gaa gcg cag gtc atg gac ttt tct gat gac 739 Asp Leu Arg Pro Pro Ile Glu Ala Gln Val Met Asp Phe Ser Asp Asp 200 205 210 att gcc tac tcg gtg cac gat gtg gaa gac ggt att gta tcc ggg cgt 787 Ile Ala Tyr Ser Val His Asp Val Glu Asp Gly Ile Val Ser Gly Arg 215 220 225 atc gac tta aaa gtg ctg tgg gac ctg gtt gaa tta gca gct ttg gca 835 Ile Asp Leu Lys Val Leu Trp Asp Leu Val Glu Leu Ala Ala Leu Ala 230 235 240 245 gac aaa gga gca gct gct ttc gga ggt tcg cct gca gag ctc atc gag 883 Asp Lys Gly Ala Ala Ala Phe Gly Gly Ser Pro Ala Glu Leu Ile Glu 250 255 260 ggt gca gca tcg ttg cgg gaa ctt ccg gtg gtg gct gcc gct gcg gat 931 Gly Ala Ala Ser Leu Arg Glu Leu Pro Val Val Ala Ala Ala Ala Asp 265 270 275 ttt gat ttc tca ctg cgt tcc tac gct gcg ctg aag gcg atg act tca 979 Phe Asp Phe Ser Leu Arg Ser Tyr Ala Ala Leu Lys Ala Met Thr Ser 280 285 290 gaa cta gtg gga aga tac gtt ggc tct acc atc gag tca aca aag aaa 1027 Glu Leu Val Gly Arg Tyr Val Gly Ser Thr Ile Glu Ser Thr Lys Lys 295 300 305 aca cac gct ggc att gat gtg gga cgc atg cac ggc gat ttg atc att 1075 Thr His Ala Gly Ile Asp Val Gly Arg Met His Gly Asp Leu Ile Ile 310 315 320 325 cca gaa aca gcg gcc agt gaa gta aaa ctg ctc aaa acg tta gcg gtt 1123 Pro Glu Thr Ala Ala Ser Glu Val Lys Leu Leu Lys Thr Leu Ala Val 330 335 340 ctc tac gtg atg gat gac cca ggg cac ctt gcg cgc caa aac agg caa 1171 Leu Tyr Val Met Asp Asp Pro Gly His Leu Ala Arg Gln Asn Arg Gln 345 350 355 cgg gat cgt atc ttc cgg gtt ttt gac tac ctg gtg ctg ggg gct ccg 1219 Arg Asp Arg Ile Phe Arg Val Phe Asp Tyr Leu Val Leu Gly Ala Pro 360 365 370 gga tcg ttg gat ccg atg tat cgc cag tgg ttt att gaa gcg gat tca 1267 Gly Ser Leu Asp Pro Met Tyr Arg Gln Trp Phe Ile Glu Ala Asp Ser 375 380 385 gaa tcg gaa cag atc cgt gtg att gtt gat cag att gcg tcg atg acg 1315 Glu Ser Glu Gln Ile Arg Val Ile Val Asp Gln Ile Ala Ser Met Thr 390 395 400 405 gag tct cgt ctg gaa cgc ctt gcc cgg aat gct gct gac atc tca gga 1363 Glu Ser Arg Leu Glu Arg Leu Ala Arg Asn Ala Ala Asp Ile Ser Gly 410 415 420 ttt ttg gga taattggtta gagcagcagt aag 1395 Phe Leu Gly <210> 1036 <211> 424 <212> PRT <213> Corynebacterium glutamicum <400> 1036 Met Tyr Pro Tyr Ser Asp Ala Asp Ala Phe Arg Arg Gln Pro Glu Arg 1 5 10 15 Ala Lys Ser Ser Gln Leu Arg Thr Ser Ala Val Asp Thr Arg Ser Ala 20 25 30 Phe Ala Arg Asp Arg Ala Arg Val Leu His Ser Ala Ala Leu Arg Arg 35 40 45 Leu Ala Asp Lys Thr Gln Val Val Gly Pro Asn Asp Gly Asp Thr Pro 50 55 60 Arg Thr Arg Leu Thr His Ser Leu Glu Val Ala Gln Ile Ala Arg Gly 65 70 75 80 Ile Gly Ala Gly Leu Asp Leu Asp Pro Asp Leu Cys Asp Leu Ala Gly 85 90 95 Leu Cys His Asp Ile Gly His Pro Pro Tyr Gly His Asn Gly Glu Asn 100 105 110 Ala Leu Asn Glu Val Ala Ala Ala Cys Gly Gly Phe Glu Gly Asn Ala 115 120 125 Gln Thr Leu Arg Ile Leu Thr Arg Leu Glu Pro Lys Ile Val Ser Asp 130 135 140 Glu Gly Glu Ser Phe Gly Leu Asn Leu Ser Arg Ala Ala Leu Asp Ala 145 150 155 160 Ala Cys Lys Tyr Pro Trp Ala Lys Thr Asn Ala Asp Gly Ser Val Asn 165 170 175 Lys Lys Tyr Ser Ala Tyr Asp Glu Asp Ala Glu Ile Leu Ala Trp Ile 180 185 190 Arg Gln Gly His Glu Asp Leu Arg Pro Pro Ile Glu Ala Gln Val Met 195 200 205 Asp Phe Ser Asp Asp Ile Ala Tyr Ser Val His Asp Val Glu Asp Gly 210 215 220 Ile Val Ser Gly Arg Ile Asp Leu Lys Val Leu Trp Asp Leu Val Glu 225 230 235 240 Leu Ala Ala Leu Ala Asp Lys Gly Ala Ala Ala Phe Gly Gly Ser Pro 245 250 255 Ala Glu Leu Ile Glu Gly Ala Ala Ser Leu Arg Glu Leu Pro Val Val 260 265 270 Ala Ala Ala Ala Asp Phe Asp Phe Ser Leu Arg Ser Tyr Ala Ala Leu 275 280 285 Lys Ala Met Thr Ser Glu Leu Val Gly Arg Tyr Val Gly Ser Thr Ile 290 295 300 Glu Ser Thr Lys Lys Thr His Ala Gly Ile Asp Val Gly Arg Met His 305 310 315 320 Gly Asp Leu Ile Ile Pro Glu Thr Ala Ala Ser Glu Val Lys Leu Leu 325 330 335 Lys Thr Leu Ala Val Leu Tyr Val Met Asp Asp Pro Gly His Leu Ala 340 345 350 Arg Gln Asn Arg Gln Arg Asp Arg Ile Phe Arg Val Phe Asp Tyr Leu 355 360 365 Val Leu Gly Ala Pro Gly Ser Leu Asp Pro Met Tyr Arg Gln Trp Phe 370 375 380 Ile Glu Ala Asp Ser Glu Ser Glu Gln Ile Arg Val Ile Val Asp Gln 385 390 395 400 Ile Ala Ser Met Thr Glu Ser Arg Leu Glu Arg Leu Ala Arg Asn Ala 405 410 415 Ala Asp Ile Ser Gly Phe Leu Gly 420 <210> 1037 <211> 1131 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1108) <223> RXN01027 <400> 1037 aatagatgga agtagttttt cattcactta tgtgcgcgtt tttaatctgg tttctaccaa 60 gaactgtgtg caccacaacg cggaaggtga atcgcaccca atg gca aat aag aac 115 Met Ala Asn Lys Asn 1 5 aat aag cct cat gag gtg gac aaa gac caa gat tca gcc atg ctg atc 163 Asn Lys Pro His Glu Val Asp Lys Asp Gln Asp Ser Ala Met Leu Ile 10 15 20 aac ggt cgc ctg caa cag atc ccg gcg cgt ccc act gag gaa ttc acc 211 Asn Gly Arg Leu Gln Gln Ile Pro Ala Arg Pro Thr Glu Glu Phe Thr 25 30 35 cgc cca act ctt gca gca ggt gca gta ctg tgg cgc ggc gac atc acc 259 Arg Pro Thr Leu Ala Ala Gly Ala Val Leu Trp Arg Gly Asp Ile Thr 40 45 50 aac ccg gac agc atc gag gtc gct gtc atc cac cgc ccg cac tat gat 307 Asn Pro Asp Ser Ile Glu Val Ala Val Ile His Arg Pro His Tyr Asp 55 60 65 gac tgg tcc ctg gcc aag ggc aaa gtc gat ccc ggc gag tct att ccg 355 Asp Trp Ser Leu Ala Lys Gly Lys Val Asp Pro Gly Glu Ser Ile Pro 70 75 80 85 aca acc gcg gcc cgt gaa atc ctt gaa gaa act ggc tac gac atc cgt 403 Thr Thr Ala Ala Arg Glu Ile Leu Glu Glu Thr Gly Tyr Asp Ile Arg 90 95 100 ctg ggc aag ctg atc ggc aag gtt act tac cct gtg ctc gac cga acc 451 Leu Gly Lys Leu Ile Gly Lys Val Thr Tyr Pro Val Leu Asp Arg Thr 105 110 115 aaa gtg gtc tac tac tgg act gcc cag gtt ctt ggt gga gag ttt gtc 499 Lys Val Val Tyr Tyr Trp Thr Ala Gln Val Leu Gly Gly Glu Phe Val 120 125 130 ccc aac gat gaa gtt gat gaa atc cgt tgg ctg tct gtt gat gaa gca 547 Pro Asn Asp Glu Val Asp Glu Ile Arg Trp Leu Ser Val Asp Glu Ala 135 140 145 tgc gag ttg ctc agc tac caa gta gat acc gaa gtt ctg gcc aag gca 595 Cys Glu Leu Leu Ser Tyr Gln Val Asp Thr Glu Val Leu Ala Lys Ala 150 155 160 165 gca aag cgt ttc cgc act cct tcc acc act cgg gtg ctg tat gtt cgc 643 Ala Lys Arg Phe Arg Thr Pro Ser Thr Thr Arg Val Leu Tyr Val Arg 170 175 180 cat gct cat gca cat ggt cgc caa acc tgg ggt ggc gac gac aat aag 691 His Ala His Ala His Gly Arg Gln Thr Trp Gly Gly Asp Asp Asn Lys 185 190 195 cgc cca ttg gac aaa aag ggg cgt cga caa gca gaa atg ctc gta ccc 739 Arg Pro Leu Asp Lys Lys Gly Arg Arg Gln Ala Glu Met Leu Val Pro 200 205 210 atg ttg ttg ccc ttc aaa ccc acc gca att tac tcg gcg gtg ccc gat 787 Met Leu Leu Pro Phe Lys Pro Thr Ala Ile Tyr Ser Ala Val Pro Asp 215 220 225 cgc tgc caa gcc acc gcg ctc ccc ctt gcc gat gag ctc ggc ctc gac 835 Arg Cys Gln Ala Thr Ala Leu Pro Leu Ala Asp Glu Leu Gly Leu Asp 230 235 240 245 gtg tcc gtc aac cga ctg ttc ggc gac gac gcc tgg gaa acc gat ccc 883 Val Ser Val Asn Arg Leu Phe Gly Asp Asp Ala Trp Glu Thr Asp Pro 250 255 260 gag gcc tgc aag aag cgc ttc acc gac gtg gtc gcg caa ggt ggc gtg 931 Glu Ala Cys Lys Lys Arg Phe Thr Asp Val Val Ala Gln Gly Gly Val 265 270 275 ccg atg atc gtt ggg cag ggc gac atc att ccg gaa atg atc aaa tgg 979 Pro Met Ile Val Gly Gln Gly Asp Ile Ile Pro Glu Met Ile Lys Trp 280 285 290 ttc tcc gag aac ggc acc ctc cct atc gat gag aag atc aag gcg aaa 1027 Phe Ser Glu Asn Gly Thr Leu Pro Ile Asp Glu Lys Ile Lys Ala Lys 295 300 305 aag ggc agc gtg tgg gtg ttg agc ttt cac gac ggt gtg ttc acc ggc 1075 Lys Gly Ser Val Trp Val Leu Ser Phe His Asp Gly Val Phe Thr Gly 310 315 320 325 gct gat tac ctg gcg agt tcc ctg ccg gtt aaa taggagcgcg tttaaggcct 1128 Ala Asp Tyr Leu Ala Ser Ser Leu Pro Val Lys 330 335 cca 1131 <210> 1038 <211> 336 <212> PRT <213> Corynebacterium glutamicum <400> 1038 Met Ala Asn Lys Asn Asn Lys Pro His Glu Val Asp Lys Asp Gln Asp 1 5 10 15 Ser Ala Met Leu Ile Asn Gly Arg Leu Gln Gln Ile Pro Ala Arg Pro 20 25 30 Thr Glu Glu Phe Thr Arg Pro Thr Leu Ala Ala Gly Ala Val Leu Trp 35 40 45 Arg Gly Asp Ile Thr Asn Pro Asp Ser Ile Glu Val Ala Val Ile His 50 55 60 Arg Pro His Tyr Asp Asp Trp Ser Leu Ala Lys Gly Lys Val Asp Pro 65 70 75 80 Gly Glu Ser Ile Pro Thr Thr Ala Ala Arg Glu Ile Leu Glu Glu Thr 85 90 95 Gly Tyr Asp Ile Arg Leu Gly Lys Leu Ile Gly Lys Val Thr Tyr Pro 100 105 110 Val Leu Asp Arg Thr Lys Val Val Tyr Tyr Trp Thr Ala Gln Val Leu 115 120 125 Gly Gly Glu Phe Val Pro Asn Asp Glu Val Asp Glu Ile Arg Trp Leu 130 135 140 Ser Val Asp Glu Ala Cys Glu Leu Leu Ser Tyr Gln Val Asp Thr Glu 145 150 155 160 Val Leu Ala Lys Ala Ala Lys Arg Phe Arg Thr Pro Ser Thr Thr Arg 165 170 175 Val Leu Tyr Val Arg His Ala His Ala His Gly Arg Gln Thr Trp Gly 180 185 190 Gly Asp Asp Asn Lys Arg Pro Leu Asp Lys Lys Gly Arg Arg Gln Ala 195 200 205 Glu Met Leu Val Pro Met Leu Leu Pro Phe Lys Pro Thr Ala Ile Tyr 210 215 220 Ser Ala Val Pro Asp Arg Cys Gln Ala Thr Ala Leu Pro Leu Ala Asp 225 230 235 240 Glu Leu Gly Leu Asp Val Ser Val Asn Arg Leu Phe Gly Asp Asp Ala 245 250 255 Trp Glu Thr Asp Pro Glu Ala Cys Lys Lys Arg Phe Thr Asp Val Val 260 265 270 Ala Gln Gly Gly Val Pro Met Ile Val Gly Gln Gly Asp Ile Ile Pro 275 280 285 Glu Met Ile Lys Trp Phe Ser Glu Asn Gly Thr Leu Pro Ile Asp Glu 290 295 300 Lys Ile Lys Ala Lys Lys Gly Ser Val Trp Val Leu Ser Phe His Asp 305 310 315 320 Gly Val Phe Thr Gly Ala Asp Tyr Leu Ala Ser Ser Leu Pro Val Lys 325 330 335 <210> 1039 <211> 757 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(757) <223> FRXA01024 <400> 1039 aatagatgga agtagttttt cattcactta tgtgcgcgtt tttaatctgg tttctaccaa 60 gaactgtgtg caccacaacg cggaaggtga atcgcaccca atg gca aat aag aac 115 Met Ala Asn Lys Asn 1 5 aat aag cct cat gag gtg gac aaa gac caa gat tca gcc atg ctg atc 163 Asn Lys Pro His Glu Val Asp Lys Asp Gln Asp Ser Ala Met Leu Ile 10 15 20 aac ggt cgc ctg caa cag atc ccg gcg cgt ccc act gag gaa ttc acc 211 Asn Gly Arg Leu Gln Gln Ile Pro Ala Arg Pro Thr Glu Glu Phe Thr 25 30 35 cgc cca act ctt gca gca ggt gca gta ctg tgg cgc ggc gac atc acc 259 Arg Pro Thr Leu Ala Ala Gly Ala Val Leu Trp Arg Gly Asp Ile Thr 40 45 50 aac ccg gac agc atc gag gtc gct gtc atc cac cgc ccg cac tat gat 307 Asn Pro Asp Ser Ile Glu Val Ala Val Ile His Arg Pro His Tyr Asp 55 60 65 gac tgg tcc ctg gcc aag ggc aaa gtc gat ccc ggc gag tct att ccg 355 Asp Trp Ser Leu Ala Lys Gly Lys Val Asp Pro Gly Glu Ser Ile Pro 70 75 80 85 aca acc gcg gcc cgt gaa atc ctt gaa gaa act ggc tac gac atc cgt 403 Thr Thr Ala Ala Arg Glu Ile Leu Glu Glu Thr Gly Tyr Asp Ile Arg 90 95 100 ctg ggc aag ctg atc ggc aag gtt act tac cct gtg ctc gac cga acc 451 Leu Gly Lys Leu Ile Gly Lys Val Thr Tyr Pro Val Leu Asp Arg Thr 105 110 115 aaa gtg gtc tac tac tgg act gcc cag gtt ctt ggt gga gag ttt gtc 499 Lys Val Val Tyr Tyr Trp Thr Ala Gln Val Leu Gly Gly Glu Phe Val 120 125 130 ccc aac gat gaa gtt gat gaa atc cgt tgg ctg tct gtt gat gaa gca 547 Pro Asn Asp Glu Val Asp Glu Ile Arg Trp Leu Ser Val Asp Glu Ala 135 140 145 tgc gag ttg ctc agc tac caa gta gat acc gaa gtt ctg gcc aag gca 595 Cys Glu Leu Leu Ser Tyr Gln Val Asp Thr Glu Val Leu Ala Lys Ala 150 155 160 165 gca aag cgt ttc cgc act cct tcc acc act cgg gtg ctg tat gtt cgc 643 Ala Lys Arg Phe Arg Thr Pro Ser Thr Thr Arg Val Leu Tyr Val Arg 170 175 180 cat gct cat gca cat ggt cgc caa acc tgg ggt ggc gac gac aat aag 691 His Ala His Ala His Gly Arg Gln Thr Trp Gly Gly Asp Asp Asn Lys 185 190 195 cgc cca ttg gac aaa aag ggg cgt cga caa gca gaa atg ctc gta ccc 739 Arg Pro Leu Asp Lys Lys Gly Arg Arg Gln Ala Glu Met Leu Val Pro 200 205 210 atg ttg ttg ccc ttc aaa 757 Met Leu Leu Pro Phe Lys 215 <210> 1040 <211> 219 <212> PRT <213> Corynebacterium glutamicum <400> 1040 Met Ala Asn Lys Asn Asn Lys Pro His Glu Val Asp Lys Asp Gln Asp 1 5 10 15 Ser Ala Met Leu Ile Asn Gly Arg Leu Gln Gln Ile Pro Ala Arg Pro 20 25 30 Thr Glu Glu Phe Thr Arg Pro Thr Leu Ala Ala Gly Ala Val Leu Trp 35 40 45 Arg Gly Asp Ile Thr Asn Pro Asp Ser Ile Glu Val Ala Val Ile His 50 55 60 Arg Pro His Tyr Asp Asp Trp Ser Leu Ala Lys Gly Lys Val Asp Pro 65 70 75 80 Gly Glu Ser Ile Pro Thr Thr Ala Ala Arg Glu Ile Leu Glu Glu Thr 85 90 95 Gly Tyr Asp Ile Arg Leu Gly Lys Leu Ile Gly Lys Val Thr Tyr Pro 100 105 110 Val Leu Asp Arg Thr Lys Val Val Tyr Tyr Trp Thr Ala Gln Val Leu 115 120 125 Gly Gly Glu Phe Val Pro Asn Asp Glu Val Asp Glu Ile Arg Trp Leu 130 135 140 Ser Val Asp Glu Ala Cys Glu Leu Leu Ser Tyr Gln Val Asp Thr Glu 145 150 155 160 Val Leu Ala Lys Ala Ala Lys Arg Phe Arg Thr Pro Ser Thr Thr Arg 165 170 175 Val Leu Tyr Val Arg His Ala His Ala His Gly Arg Gln Thr Trp Gly 180 185 190 Gly Asp Asp Asn Lys Arg Pro Leu Asp Lys Lys Gly Arg Arg Gln Ala 195 200 205 Glu Met Leu Val Pro Met Leu Leu Pro Phe Lys 210 215 <210> 1041 <211> 257 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(234) <223> FRXA01027 <400> 1041 acc gat ccc gag gcc tgc aag aag cgc ttc acc gac gtg gtc gcg caa 48 Thr Asp Pro Glu Ala Cys Lys Lys Arg Phe Thr Asp Val Val Ala Gln 1 5 10 15 ggt ggc gtg ccg atg atc gtt ggg cag ggc gac atc att ccg gaa atg 96 Gly Gly Val Pro Met Ile Val Gly Gln Gly Asp Ile Ile Pro Glu Met 20 25 30 atc aaa tgg ttc tcc gag aac ggc acc ctc cct atc gat gag aag atc 144 Ile Lys Trp Phe Ser Glu Asn Gly Thr Leu Pro Ile Asp Glu Lys Ile 35 40 45 aag gcg aaa aag ggc agc gtg tgg gtg ttg agc ttt cac gac ggt gtg 192 Lys Ala Lys Lys Gly Ser Val Trp Val Leu Ser Phe His Asp Gly Val 50 55 60 ttc acc ggc gct gat tac ctg gcg agt tcc ctg ccg gtt aaa 234 Phe Thr Gly Ala Asp Tyr Leu Ala Ser Ser Leu Pro Val Lys 65 70 75 taggagcgcg tttaaggcct cca 257 <210> 1042 <211> 78 <212> PRT <213> Corynebacterium glutamicum <400> 1042 Thr Asp Pro Glu Ala Cys Lys Lys Arg Phe Thr Asp Val Val Ala Gln 1 5 10 15 Gly Gly Val Pro Met Ile Val Gly Gln Gly Asp Ile Ile Pro Glu Met 20 25 30 Ile Lys Trp Phe Ser Glu Asn Gly Thr Leu Pro Ile Asp Glu Lys Ile 35 40 45 Lys Ala Lys Lys Gly Ser Val Trp Val Leu Ser Phe His Asp Gly Val 50 55 60 Phe Thr Gly Ala Asp Tyr Leu Ala Ser Ser Leu Pro Val Lys 65 70 75 <210> 1043 <211> 651 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(628) <223> RXA01528 <400> 1043 cacccaaacc caaacctctc agtcgaataa gcagaagtct caggacaacc gcaggggtaa 60 gggtcgtagg tctccaacca ggaggcgttc caacacgagg gtg aat cag gcg tgg 115 Val Asn Gln Ala Trp 1 5 cag cag tcc cgt ttg gtt act tct gat gag act tcc gca ggt ggt ctc 163 Gln Gln Ser Arg Leu Val Thr Ser Asp Glu Thr Ser Ala Gly Gly Leu 10 15 20 gtg gtg tca ggt ttg gct gag gcg gtc aac gct aac aat gag gtt gat 211 Val Val Ser Gly Leu Ala Glu Ala Val Asn Ala Asn Asn Glu Val Asp 25 30 35 ctg tcg aag att tat gtt gcg ttg att ggt cgc ctt gat cgt cgt ggt 259 Leu Ser Lys Ile Tyr Val Ala Leu Ile Gly Arg Leu Asp Arg Arg Gly 40 45 50 cgt ttg ttg tgg tcg atg ccg aag ggc cat gtt gag cct ggt gag gat 307 Arg Leu Leu Trp Ser Met Pro Lys Gly His Val Glu Pro Gly Glu Asp 55 60 65 aag gct gcg act gct gag cgt gag gtg tgg gag gag acc ggc atc cac 355 Lys Ala Ala Thr Ala Glu Arg Glu Val Trp Glu Glu Thr Gly Ile His 70 75 80 85 ggt gag gtg ttc act gag ttg ggt gtg att gat tat tgg ttc gtt tcg 403 Gly Glu Val Phe Thr Glu Leu Gly Val Ile Asp Tyr Trp Phe Val Ser 90 95 100 gaa ggg aag cgg atc cat aag acg gtg cat cat cat ttg ttg cgt tat 451 Glu Gly Lys Arg Ile His Lys Thr Val His His His Leu Leu Arg Tyr 105 110 115 gtt gat ggc gat ttg aat gat gag gat cca gaa gtc act gag gtg gcg 499 Val Asp Gly Asp Leu Asn Asp Glu Asp Pro Glu Val Thr Glu Val Ala 120 125 130 tgg att ccg gcg aat cag ttg att gag cat ttg gct ttt gcg gat gag 547 Trp Ile Pro Ala Asn Gln Leu Ile Glu His Leu Ala Phe Ala Asp Glu 135 140 145 cgg aag ttg gct agg cag gcg cat gat ttg ttg cct gag ttt gct ttg 595 Arg Lys Leu Ala Arg Gln Ala His Asp Leu Leu Pro Glu Phe Ala Leu 150 155 160 165 aag gaa aag gcg gag gga agg tcc acc cca agg tgattccgaa ccccaacccg 648 Lys Glu Lys Ala Glu Gly Arg Ser Thr Pro Arg 170 175 aac 651 <210> 1044 <211> 176 <212> PRT <213> Corynebacterium glutamicum <400> 1044 Val Asn Gln Ala Trp Gln Gln Ser Arg Leu Val Thr Ser Asp Glu Thr 1 5 10 15 Ser Ala Gly Gly Leu Val Val Ser Gly Leu Ala Glu Ala Val Asn Ala 20 25 30 Asn Asn Glu Val Asp Leu Ser Lys Ile Tyr Val Ala Leu Ile Gly Arg 35 40 45 Leu Asp Arg Arg Gly Arg Leu Leu Trp Ser Met Pro Lys Gly His Val 50 55 60 Glu Pro Gly Glu Asp Lys Ala Ala Thr Ala Glu Arg Glu Val Trp Glu 65 70 75 80 Glu Thr Gly Ile His Gly Glu Val Phe Thr Glu Leu Gly Val Ile Asp 85 90 95 Tyr Trp Phe Val Ser Glu Gly Lys Arg Ile His Lys Thr Val His His 100 105 110 His Leu Leu Arg Tyr Val Asp Gly Asp Leu Asn Asp Glu Asp Pro Glu 115 120 125 Val Thr Glu Val Ala Trp Ile Pro Ala Asn Gln Leu Ile Glu His Leu 130 135 140 Ala Phe Ala Asp Glu Arg Lys Leu Ala Arg Gln Ala His Asp Leu Leu 145 150 155 160 Pro Glu Phe Ala Leu Lys Glu Lys Ala Glu Gly Arg Ser Thr Pro Arg 165 170 175 <210> 1045 <211> 541 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(541) <223> RXA00072 <400> 1045 acggccagga cgatccagtg cacaggccag caccagcaaa gtccacatcg caagcattaa 60 aagaatctct cgaaagacac aaaagaggtg agtcgcaaca atg agc ttt caa cta 115 Met Ser Phe Gln Leu 1 5 gtt aac gcc ctg aaa aat act ggt tcg gta aaa gat ccc gag atc tca 163 Val Asn Ala Leu Lys Asn Thr Gly Ser Val Lys Asp Pro Glu Ile Ser 10 15 20 ccc gaa gga cct cgc acg acc aca ccg ttg tca cca gag gta gca aaa 211 Pro Glu Gly Pro Arg Thr Thr Thr Pro Leu Ser Pro Glu Val Ala Lys 25 30 35 cat aac gag gaa ctc gtc gaa aag cat gct gct gcg ttg tat gac gcc 259 His Asn Glu Glu Leu Val Glu Lys His Ala Ala Ala Leu Tyr Asp Ala 40 45 50 agc gcg caa gag atc ctg gaa tgg aca gcc gag cac gcg ccg ggc gct 307 Ser Ala Gln Glu Ile Leu Glu Trp Thr Ala Glu His Ala Pro Gly Ala 55 60 65 att gca gtg acc ttg agc atg gaa aac acc gtg ctg gcg gag ctg gct 355 Ile Ala Val Thr Leu Ser Met Glu Asn Thr Val Leu Ala Glu Leu Ala 70 75 80 85 gcg cgg cac ctg ccg gaa gct gat ttc ctc ttt ttg gac acc ggt tac 403 Ala Arg His Leu Pro Glu Ala Asp Phe Leu Phe Leu Asp Thr Gly Tyr 90 95 100 cac ttc aag gag acc ctt gaa gtt gcc cgt cag gta gat gag cgc tat 451 His Phe Lys Glu Thr Leu Glu Val Ala Arg Gln Val Asp Glu Arg Tyr 105 110 115 tcc cag aag ctt gtc acc gcg ctg ccg atc ctc aag cgc acg gag cag 499 Ser Gln Lys Leu Val Thr Ala Leu Pro Ile Leu Lys Arg Thr Glu Gln 120 125 130 gat tcc att tat ggt ctc aac ctg tac cgc agc aac cca gcg 541 Asp Ser Ile Tyr Gly Leu Asn Leu Tyr Arg Ser Asn Pro Ala 135 140 145 <210> 1046 <211> 147 <212> PRT <213> Corynebacterium glutamicum <400> 1046 Met Ser Phe Gln Leu Val Asn Ala Leu Lys Asn Thr Gly Ser Val Lys 1 5 10 15 Asp Pro Glu Ile Ser Pro Glu Gly Pro Arg Thr Thr Thr Pro Leu Ser 20 25 30 Pro Glu Val Ala Lys His Asn Glu Glu Leu Val Glu Lys His Ala Ala 35 40 45 Ala Leu Tyr Asp Ala Ser Ala Gln Glu Ile Leu Glu Trp Thr Ala Glu 50 55 60 His Ala Pro Gly Ala Ile Ala Val Thr Leu Ser Met Glu Asn Thr Val 65 70 75 80 Leu Ala Glu Leu Ala Ala Arg His Leu Pro Glu Ala Asp Phe Leu Phe 85 90 95 Leu Asp Thr Gly Tyr His Phe Lys Glu Thr Leu Glu Val Ala Arg Gln 100 105 110 Val Asp Glu Arg Tyr Ser Gln Lys Leu Val Thr Ala Leu Pro Ile Leu 115 120 125 Lys Arg Thr Glu Gln Asp Ser Ile Tyr Gly Leu Asn Leu Tyr Arg Ser 130 135 140 Asn Pro Ala 145 <210> 1047 <211> 1002 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(979) <223> RXA01878 <400> 1047 ggttcaggct gcacaaggtt ggggagcatg gcctgcttgc accgcaagct tgggcatccg 60 atagtagaaa tctggcatcc aataggtaga ttgggatgct atg gaa gaa ccc tca 115 Met Glu Glu Pro Ser 1 5 ggt gca cag ctg ctc ggc ccg gta gaa atc cgt gcg ctg gca gaa aag 163 Gly Ala Gln Leu Leu Gly Pro Val Glu Ile Arg Ala Leu Ala Glu Lys 10 15 20 ctc gac gtc aca cca act aag aag ttg ggg cag aac ttt gtt cac gat 211 Leu Asp Val Thr Pro Thr Lys Lys Leu Gly Gln Asn Phe Val His Asp 25 30 35 ccc aac acg gtg cgt cgc att gtt gct gcg gca gag ctc acc cca aac 259 Pro Asn Thr Val Arg Arg Ile Val Ala Ala Ala Glu Leu Thr Pro Asn 40 45 50 gac cac gtg gtg gaa gtt ggc cct ggt ctg ggc tct ctg acc ctt gcc 307 Asp His Val Val Glu Val Gly Pro Gly Leu Gly Ser Leu Thr Leu Ala 55 60 65 ctg gtg gaa tct gct gct tca gta act gcg gtg gaa att gat ccc cgt 355 Leu Val Glu Ser Ala Ala Ser Val Thr Ala Val Glu Ile Asp Pro Arg 70 75 80 85 ttg gct gcg gaa ttg ccg gag act ttt cag tgg cgc gcg ccg gcc ctt 403 Leu Ala Ala Glu Leu Pro Glu Thr Phe Gln Trp Arg Ala Pro Ala Leu 90 95 100 gct cac aag ttg agc atc gtg ctg aaa gac gcc ctg aag gtt caa caa 451 Ala His Lys Leu Ser Ile Val Leu Lys Asp Ala Leu Lys Val Gln Gln 105 110 115 tcc gat atg gct gtt caa ccc acc gcc ttg gtg gct aac ttg ccg tac 499 Ser Asp Met Ala Val Gln Pro Thr Ala Leu Val Ala Asn Leu Pro Tyr 120 125 130 aac gtc tct gtc cct gtc ttg ttg cac atg atg gag gag ttt ccc acc 547 Asn Val Ser Val Pro Val Leu Leu His Met Met Glu Glu Phe Pro Thr 135 140 145 atc aac aag gtg ctt gtc atg gtg cag gca gag gtt gct gat cgt ttg 595 Ile Asn Lys Val Leu Val Met Val Gln Ala Glu Val Ala Asp Arg Leu 150 155 160 165 gct gcg gat cca gga tcg aag att tat ggt gtg cct agc gtg aag gcg 643 Ala Ala Asp Pro Gly Ser Lys Ile Tyr Gly Val Pro Ser Val Lys Ala 170 175 180 tcc ttc tac ggt cca gtt act cgc gcc ggg tcg att ggt aag aat gtc 691 Ser Phe Tyr Gly Pro Val Thr Arg Ala Gly Ser Ile Gly Lys Asn Val 185 190 195 ttt tgg cca gct cca aag atc gaa tcc ggt ttg gtg aag atc gtg cgc 739 Phe Trp Pro Ala Pro Lys Ile Glu Ser Gly Leu Val Lys Ile Val Arg 200 205 210 gaa gac acc gcg tgg aag cag gac gat gag acg cgt aag aag gtg tgg 787 Glu Asp Thr Ala Trp Lys Gln Asp Asp Glu Thr Arg Lys Lys Val Trp 215 220 225 ccg atc att gat gct gct ttc ttg cag cgc cgt aaa acc cta aga gct 835 Pro Ile Ile Asp Ala Ala Phe Leu Gln Arg Arg Lys Thr Leu Arg Ala 230 235 240 245 gcg ctt tct gga cac tac ggt tct ggc cag gca gct gag gaa gct ttg 883 Ala Leu Ser Gly His Tyr Gly Ser Gly Gln Ala Ala Glu Glu Ala Leu 250 255 260 cgg gcc gct gat att gat cca acg ctt cgt ggc gaa aag ctt gat gtc 931 Arg Ala Ala Asp Ile Asp Pro Thr Leu Arg Gly Glu Lys Leu Asp Val 265 270 275 act gac tat gtg cgc cta gct ggg gtg ttg cag caa aag gat gag aag 979 Thr Asp Tyr Val Arg Leu Ala Gly Val Leu Gln Gln Lys Asp Glu Lys 280 285 290 tgaaaattac cgctaaggcg tgg 1002 <210> 1048 <211> 293 <212> PRT <213> Corynebacterium glutamicum <400> 1048 Met Glu Glu Pro Ser Gly Ala Gln Leu Leu Gly Pro Val Glu Ile Arg 1 5 10 15 Ala Leu Ala Glu Lys Leu Asp Val Thr Pro Thr Lys Lys Leu Gly Gln 20 25 30 Asn Phe Val His Asp Pro Asn Thr Val Arg Arg Ile Val Ala Ala Ala 35 40 45 Glu Leu Thr Pro Asn Asp His Val Val Glu Val Gly Pro Gly Leu Gly 50 55 60 Ser Leu Thr Leu Ala Leu Val Glu Ser Ala Ala Ser Val Thr Ala Val 65 70 75 80 Glu Ile Asp Pro Arg Leu Ala Ala Glu Leu Pro Glu Thr Phe Gln Trp 85 90 95 Arg Ala Pro Ala Leu Ala His Lys Leu Ser Ile Val Leu Lys Asp Ala 100 105 110 Leu Lys Val Gln Gln Ser Asp Met Ala Val Gln Pro Thr Ala Leu Val 115 120 125 Ala Asn Leu Pro Tyr Asn Val Ser Val Pro Val Leu Leu His Met Met 130 135 140 Glu Glu Phe Pro Thr Ile Asn Lys Val Leu Val Met Val Gln Ala Glu 145 150 155 160 Val Ala Asp Arg Leu Ala Ala Asp Pro Gly Ser Lys Ile Tyr Gly Val 165 170 175 Pro Ser Val Lys Ala Ser Phe Tyr Gly Pro Val Thr Arg Ala Gly Ser 180 185 190 Ile Gly Lys Asn Val Phe Trp Pro Ala Pro Lys Ile Glu Ser Gly Leu 195 200 205 Val Lys Ile Val Arg Glu Asp Thr Ala Trp Lys Gln Asp Asp Glu Thr 210 215 220 Arg Lys Lys Val Trp Pro Ile Ile Asp Ala Ala Phe Leu Gln Arg Arg 225 230 235 240 Lys Thr Leu Arg Ala Ala Leu Ser Gly His Tyr Gly Ser Gly Gln Ala 245 250 255 Ala Glu Glu Ala Leu Arg Ala Ala Asp Ile Asp Pro Thr Leu Arg Gly 260 265 270 Glu Lys Leu Asp Val Thr Asp Tyr Val Arg Leu Ala Gly Val Leu Gln 275 280 285 Gln Lys Asp Glu Lys 290 <210> 1049 <211> 1545 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1531) <223> RXN02281 <400> 1049 aagatcaaca acgccgccga ggtcaacttg gaaattatca cgtgaggatt cttgcatacg 60 cctataaaag cacagttttg aatccacagg gcatcagggc gtg cag aaa gat agt 115 Val Gln Lys Asp Ser 1 5 gtg gtg cgc atg gaa gca aca acg atc gat gac gca atc gcg aag ctc 163 Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp Ala Ile Ala Lys Leu 10 15 20 att gac atc tac gac acc tcg acc aaa ctg gcc aaa gaa acc ctc aac 211 Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala Lys Glu Thr Leu Asn 25 30 35 aat gag gac tac gcc gca tac gcc gat gtt gtt tac ccc aaa ctc acc 259 Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val Tyr Pro Lys Leu Thr 40 45 50 gtt gac gtg ctg gaa tgg aaa ccc atc gac cgc acc gaa ccc ttc ggc 307 Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg Thr Glu Pro Phe Gly 55 60 65 tat gtg gat cga gcc ggg cga tac tcc gcc acc ttg tcc aaa cca cgc 355 Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr Leu Ser Lys Pro Arg 70 75 80 85 gtg att gag cgt tac ctc cgc gaa caa ctc gag cgt ctc acc agt aat 403 Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu Arg Leu Thr Ser Asn 90 95 100 tat ccc tgc aag att tac gta tct gag tca gat atc cgc atc cca ccg 451 Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp Ile Arg Ile Pro Pro 105 110 115 gag tac att cgc ggc gca cct tcc gct acc gaa gct cgc cgt gct ggt 499 Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu Ala Arg Arg Ala Gly 120 125 130 gat gtt gca gat atc atc cca cgc ccc acc ctg gat gaa gtc cac gac 547 Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu Asp Glu Val His Asp 135 140 145 gca att atc gac ggc gac tgg cac gcc ttc aac ggc ccc gaa ctc ccg 595 Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn Gly Pro Glu Leu Pro 150 155 160 165 ctt ttc cac ttc ggg ccg caa cgc ttc gac atc gcc tgc gcc cgc atc 643 Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile Ala Cys Ala Arg Ile 170 175 180 gag cac tac acc ggc atc aac gtg gaa cac gtg cag aag tac att ctg 691 Glu His Tyr Thr Gly Ile Asn Val Glu His Val Gln Lys Tyr Ile Leu 185 190 195 ttc acc aac tac gcc atg cac acc acc gag ttc gtg cat ttt gcc atg 739 Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe Val His Phe Ala Met 200 205 210 tcc gaa ctc acc tcg gaa gac tcc cgc tac gtg ggt cta tcc ttg cca 787 Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val Gly Leu Ser Leu Pro 215 220 225 aac ggg cag gta att gac cga gag acc gcc acc agc ctc ggt acg gaa 835 Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr Ser Leu Gly Thr Glu 230 235 240 245 acc ctt gat ctg act agc cgt ttc caa atg cct cgt tac gat ctc atc 883 Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro Arg Tyr Asp Leu Ile 250 255 260 acc gaa gcc ggt gac ggt att acc att atc aac atc ggt gtg ggc cca 931 Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn Ile Gly Val Gly Pro 265 270 275 tcc aat gca aaa act atc acc gac tgc ctt gct gtg ctc cgc cca gaa 979 Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala Val Leu Arg Pro Glu 280 285 290 gcc tgg gtg atg atc ggc cac tgt gct ggc atg gac gcc cgc atg cgc 1027 Ala Trp Val Met Ile Gly His Cys Ala Gly Met Asp Ala Arg Met Arg 295 300 305 atc ggc gac ctc atc ctt ggc aac gcc tac cag cgc gaa gac cac att 1075 Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln Arg Glu Asp His Ile 310 315 320 325 ctg aat acc cgc atc cca ctt ggt aat ccg atc ccg gca ata cca gaa 1123 Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile Pro Ala Ile Pro Glu 330 335 340 atc caa aaa gct cta gaa gcc agc gtc gac gaa atc tac gga tcc gac 1171 Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu Ile Tyr Gly Ser Asp 345 350 355 aac agc ctc atg cgc acc ggt acg gtc tta tcc acc gac gac cga aac 1219 Asn Ser Leu Met Arg Thr Gly Thr Val Leu Ser Thr Asp Asp Arg Asn 360 365 370 tgg gaa tgg cac acc cca gaa aac ctc tgg aac tgg ctc aaa gga tcc 1267 Trp Glu Trp His Thr Pro Glu Asn Leu Trp Asn Trp Leu Lys Gly Ser 375 380 385 acc gcc gca gct gtt gac atg gaa tct tcc acc ttg gcc acc aac gga 1315 Thr Ala Ala Ala Val Asp Met Glu Ser Ser Thr Leu Ala Thr Asn Gly 390 395 400 405 tat cga ttc cgc att cca tac ggc acc ctg ctg agc gtc tct gac ctg 1363 Tyr Arg Phe Arg Ile Pro Tyr Gly Thr Leu Leu Ser Val Ser Asp Leu 410 415 420 cca cta cac gca gtg ccg aaa ctt tcc gcg caa gcg cag gcg ttt tac 1411 Pro Leu His Ala Val Pro Lys Leu Ser Ala Gln Ala Gln Ala Phe Tyr 425 430 435 ttc aac tcc aag gaa gcc cac gtc atg tgt gct gtt cgt gca atg gaa 1459 Phe Asn Ser Lys Glu Ala His Val Met Cys Ala Val Arg Ala Met Glu 440 445 450 tac ctg gca gta gat cct gaa cgg ttg cgt acc cgt aaa ctg cgc agg 1507 Tyr Leu Ala Val Asp Pro Glu Arg Leu Arg Thr Arg Lys Leu Arg Arg 455 460 465 acc ttg ggt gag gtg ccg ttt cgc taaagtctcg gaga 1545 Thr Leu Gly Glu Val Pro Phe Arg 470 475 <210> 1050 <211> 477 <212> PRT <213> Corynebacterium glutamicum <400> 1050 Val Gln Lys Asp Ser Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp 1 5 10 15 Ala Ile Ala Lys Leu Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala 20 25 30 Lys Glu Thr Leu Asn Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val 35 40 45 Tyr Pro Lys Leu Thr Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg 50 55 60 Thr Glu Pro Phe Gly Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr 65 70 75 80 Leu Ser Lys Pro Arg Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu 85 90 95 Arg Leu Thr Ser Asn Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp 100 105 110 Ile Arg Ile Pro Pro Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu 115 120 125 Ala Arg Arg Ala Gly Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu 130 135 140 Asp Glu Val His Asp Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn 145 150 155 160 Gly Pro Glu Leu Pro Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile 165 170 175 Ala Cys Ala Arg Ile Glu His Tyr Thr Gly Ile Asn Val Glu His Val 180 185 190 Gln Lys Tyr Ile Leu Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe 195 200 205 Val His Phe Ala Met Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val 210 215 220 Gly Leu Ser Leu Pro Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr 225 230 235 240 Ser Leu Gly Thr Glu Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro 245 250 255 Arg Tyr Asp Leu Ile Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn 260 265 270 Ile Gly Val Gly Pro Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala 275 280 285 Val Leu Arg Pro Glu Ala Trp Val Met Ile Gly His Cys Ala Gly Met 290 295 300 Asp Ala Arg Met Arg Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln 305 310 315 320 Arg Glu Asp His Ile Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile 325 330 335 Pro Ala Ile Pro Glu Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu 340 345 350 Ile Tyr Gly Ser Asp Asn Ser Leu Met Arg Thr Gly Thr Val Leu Ser 355 360 365 Thr Asp Asp Arg Asn Trp Glu Trp His Thr Pro Glu Asn Leu Trp Asn 370 375 380 Trp Leu Lys Gly Ser Thr Ala Ala Ala Val Asp Met Glu Ser Ser Thr 385 390 395 400 Leu Ala Thr Asn Gly Tyr Arg Phe Arg Ile Pro Tyr Gly Thr Leu Leu 405 410 415 Ser Val Ser Asp Leu Pro Leu His Ala Val Pro Lys Leu Ser Ala Gln 420 425 430 Ala Gln Ala Phe Tyr Phe Asn Ser Lys Glu Ala His Val Met Cys Ala 435 440 445 Val Arg Ala Met Glu Tyr Leu Ala Val Asp Pro Glu Arg Leu Arg Thr 450 455 460 Arg Lys Leu Arg Arg Thr Leu Gly Glu Val Pro Phe Arg 465 470 475 <210> 1051 <211> 1191 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1168) <223> FRXA02281 <400> 1051 aagatcaaca acgccgccga ggtcaacttg gaaattatca cgtgaggatt cttgcatacg 60 cctataaaag cacagttttg aatccacagg gcatcagggc gtg cag aaa gat agt 115 Val Gln Lys Asp Ser 1 5 gtg gtg cgc atg gaa gca aca acg atc gat gac gca atc gcg aag ctc 163 Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp Ala Ile Ala Lys Leu 10 15 20 att gac atc tac gac acc tcg acc aaa ctg gcc aaa gaa acc ctc aac 211 Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala Lys Glu Thr Leu Asn 25 30 35 aat gag gac tac gcc gca tac gcc gat gtt gtt tac ccc aaa ctc acc 259 Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val Tyr Pro Lys Leu Thr 40 45 50 gtt gac gtg ctg gaa tgg aaa ccc atc gac cgc acc gaa ccc ttc ggc 307 Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg Thr Glu Pro Phe Gly 55 60 65 tat gtg gat cga gcc ggg cga tac tcc gcc acc ttg tcc aaa cca cgc 355 Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr Leu Ser Lys Pro Arg 70 75 80 85 gtg att gag cgt tac ctc cgc gaa caa ctc gag cgt ctc acc agt aat 403 Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu Arg Leu Thr Ser Asn 90 95 100 tat ccc tgc aag att tac gta tct gag tca gat atc cgc atc cca ccg 451 Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp Ile Arg Ile Pro Pro 105 110 115 gag tac att cgc ggc gca cct tcc gct acc gaa gct cgc cgt gct ggt 499 Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu Ala Arg Arg Ala Gly 120 125 130 gat gtt gca gat atc atc cca cgc ccc acc ctg gat gaa gtc cac gac 547 Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu Asp Glu Val His Asp 135 140 145 gca att atc gac ggc gac tgg cac gcc ttc aac ggc ccc gaa ctc ccg 595 Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn Gly Pro Glu Leu Pro 150 155 160 165 ctt ttc cac ttc ggg ccg caa cgc ttc gac atc gcc tgc gcc cgc atc 643 Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile Ala Cys Ala Arg Ile 170 175 180 gag cac tac acc ggc atc aac gtg gaa cac gtg cag aag tac att ctg 691 Glu His Tyr Thr Gly Ile Asn Val Glu His Val Gln Lys Tyr Ile Leu 185 190 195 ttc acc aac tac gcc atg cac acc acc gag ttc gtg cat ttt gcc atg 739 Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe Val His Phe Ala Met 200 205 210 tcc gaa ctc acc tcg gaa gac tcc cgc tac gtg ggt cta tcc ttg cca 787 Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val Gly Leu Ser Leu Pro 215 220 225 aac ggg cag gta att gac cga gag acc gcc acc agc ctc ggt acg gaa 835 Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr Ser Leu Gly Thr Glu 230 235 240 245 acc ctt gat ctg act agc cgt ttc caa atg cct cgt tac gat ctc atc 883 Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro Arg Tyr Asp Leu Ile 250 255 260 acc gaa gcc ggt gac ggt att acc att atc aac atc ggt gtg ggc cca 931 Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn Ile Gly Val Gly Pro 265 270 275 tcc aat gca aaa act atc acc gac tgc ctt gct gtg ctc cgc cca gaa 979 Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala Val Leu Arg Pro Glu 280 285 290 gcc tgg gtg atg atc ggc cac tgt gct ggc atg gac gcc cgc atg cgc 1027 Ala Trp Val Met Ile Gly His Cys Ala Gly Met Asp Ala Arg Met Arg 295 300 305 atc ggc gac ctc atc ctt ggc aac gcc tac cag cgc gaa gac cac att 1075 Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln Arg Glu Asp His Ile 310 315 320 325 ctg aat acc cgc atc cca ctt ggt aat ccg atc ccg gca ata cca gaa 1123 Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile Pro Ala Ile Pro Glu 330 335 340 atc caa aaa gct cta gaa gcc agc gtc gac gaa atc tac gga tcc 1168 Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu Ile Tyr Gly Ser 345 350 355 tagtattcta tagtgtcacc taa 1191 <210> 1052 <211> 356 <212> PRT <213> Corynebacterium glutamicum <400> 1052 Val Gln Lys Asp Ser Val Val Arg Met Glu Ala Thr Thr Ile Asp Asp 1 5 10 15 Ala Ile Ala Lys Leu Ile Asp Ile Tyr Asp Thr Ser Thr Lys Leu Ala 20 25 30 Lys Glu Thr Leu Asn Asn Glu Asp Tyr Ala Ala Tyr Ala Asp Val Val 35 40 45 Tyr Pro Lys Leu Thr Val Asp Val Leu Glu Trp Lys Pro Ile Asp Arg 50 55 60 Thr Glu Pro Phe Gly Tyr Val Asp Arg Ala Gly Arg Tyr Ser Ala Thr 65 70 75 80 Leu Ser Lys Pro Arg Val Ile Glu Arg Tyr Leu Arg Glu Gln Leu Glu 85 90 95 Arg Leu Thr Ser Asn Tyr Pro Cys Lys Ile Tyr Val Ser Glu Ser Asp 100 105 110 Ile Arg Ile Pro Pro Glu Tyr Ile Arg Gly Ala Pro Ser Ala Thr Glu 115 120 125 Ala Arg Arg Ala Gly Asp Val Ala Asp Ile Ile Pro Arg Pro Thr Leu 130 135 140 Asp Glu Val His Asp Ala Ile Ile Asp Gly Asp Trp His Ala Phe Asn 145 150 155 160 Gly Pro Glu Leu Pro Leu Phe His Phe Gly Pro Gln Arg Phe Asp Ile 165 170 175 Ala Cys Ala Arg Ile Glu His Tyr Thr Gly Ile Asn Val Glu His Val 180 185 190 Gln Lys Tyr Ile Leu Phe Thr Asn Tyr Ala Met His Thr Thr Glu Phe 195 200 205 Val His Phe Ala Met Ser Glu Leu Thr Ser Glu Asp Ser Arg Tyr Val 210 215 220 Gly Leu Ser Leu Pro Asn Gly Gln Val Ile Asp Arg Glu Thr Ala Thr 225 230 235 240 Ser Leu Gly Thr Glu Thr Leu Asp Leu Thr Ser Arg Phe Gln Met Pro 245 250 255 Arg Tyr Asp Leu Ile Thr Glu Ala Gly Asp Gly Ile Thr Ile Ile Asn 260 265 270 Ile Gly Val Gly Pro Ser Asn Ala Lys Thr Ile Thr Asp Cys Leu Ala 275 280 285 Val Leu Arg Pro Glu Ala Trp Val Met Ile Gly His Cys Ala Gly Met 290 295 300 Asp Ala Arg Met Arg Ile Gly Asp Leu Ile Leu Gly Asn Ala Tyr Gln 305 310 315 320 Arg Glu Asp His Ile Leu Asn Thr Arg Ile Pro Leu Gly Asn Pro Ile 325 330 335 Pro Ala Ile Pro Glu Ile Gln Lys Ala Leu Glu Ala Ser Val Asp Glu 340 345 350 Ile Tyr Gly Ser 355 <210> 1053 <211> 1146 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1123) <223> RXN01240 <400> 1053 ttgttctcac atctacccgt atctttgttg gttttagtac ccgatagtga gttttgatcc 60 ctgcacagga aagttagcgg cgctactatg aacgatcgat atg tct gac aac act 115 Met Ser Asp Asn Thr 1 5 ctc tcc caa ttt ggc agt tac tac cac gaa ttc cga cgt gcc cat ccc 163 Leu Ser Gln Phe Gly Ser Tyr Tyr His Glu Phe Arg Arg Ala His Pro 10 15 20 atg gcc gac gtc gaa ttc ctc cta gca att gaa gaa tta ctt acg gac 211 Met Ala Asp Val Glu Phe Leu Leu Ala Ile Glu Glu Leu Leu Thr Asp 25 30 35 ggt ggt gtc acc ttc gat cgc gtc acc aca cgc atc aaa gaa tgg tca 259 Gly Gly Val Thr Phe Asp Arg Val Thr Thr Arg Ile Lys Glu Trp Ser 40 45 50 agc ctg aaa gcc aag gct cgc aag cgt cgc aac gat ggc tcg ttg atc 307 Ser Leu Lys Ala Lys Ala Arg Lys Arg Arg Asn Asp Gly Ser Leu Ile 55 60 65 tac cct gat ccg cgc aaa gac atc cac gac atg atc ggt gtt cgg atc 355 Tyr Pro Asp Pro Arg Lys Asp Ile His Asp Met Ile Gly Val Arg Ile 70 75 80 85 acc acg tac cac tcc acg gaa ata ccc gtg gcc cta aaa gtg ctc caa 403 Thr Thr Tyr His Ser Thr Glu Ile Pro Val Ala Leu Lys Val Leu Gln 90 95 100 gac tcc ttc atc gtc cac aaa tcc gta gac aaa gcc gct gaa act cgc 451 Asp Ser Phe Ile Val His Lys Ser Val Asp Lys Ala Ala Glu Thr Arg 105 110 115 atc tca ggc ggc ttt ggt tac ggc tcc cac cac ctg att ctg gaa gtc 499 Ile Ser Gly Gly Phe Gly Tyr Gly Ser His His Leu Ile Leu Glu Val 120 125 130 gat gac acc tcc gat gac ctc cag gac tac aaa ggc ctc gtc ttt gaa 547 Asp Asp Thr Ser Asp Asp Leu Gln Asp Tyr Lys Gly Leu Val Phe Glu 135 140 145 gtt cag gtg cgc acc gtg ctg caa cac gcc tgg gca gag ttc gaa cac 595 Val Gln Val Arg Thr Val Leu Gln His Ala Trp Ala Glu Phe Glu His 150 155 160 165 gat atc cgc tat aaa cgc gcc gat gtg tcc aac cca gaa gac ttc agc 643 Asp Ile Arg Tyr Lys Arg Ala Asp Val Ser Asn Pro Glu Asp Phe Ser 170 175 180 gca gaa gta gac cgc atg ttc acc ctc gct gcc gga ctc atc gaa tta 691 Ala Glu Val Asp Arg Met Phe Thr Leu Ala Ala Gly Leu Ile Glu Leu 185 190 195 gcg gac caa caa ttc gac caa atc gcc gca ctc aaa gaa acc agc cga 739 Ala Asp Gln Gln Phe Asp Gln Ile Ala Ala Leu Lys Glu Thr Ser Arg 200 205 210 gtt gct gat gaa tcc gtc gaa ctc acc gca gag aca ctt ccc ggc gtt 787 Val Ala Asp Glu Ser Val Glu Leu Thr Ala Glu Thr Leu Pro Gly Val 215 220 225 ctt gcc atg ctc att ggc aac cgc ttc ccc cgc cca cgc tcc aca aac 835 Leu Ala Met Leu Ile Gly Asn Arg Phe Pro Arg Pro Arg Ser Thr Asn 230 235 240 245 tac cgc ttc ctc gaa gac atc ctg gtg gcc aac tcc att acc tct gtg 883 Tyr Arg Phe Leu Glu Asp Ile Leu Val Ala Asn Ser Ile Thr Ser Val 250 255 260 gtg cag ctg cgc gag ctg ctc aac ccc acc gac att gaa gtg ctg ttg 931 Val Gln Leu Arg Glu Leu Leu Asn Pro Thr Asp Ile Glu Val Leu Leu 265 270 275 aaa gta atg aac tac cgc ttc cac cca ggc cag atc cgc atc atc gac 979 Lys Val Met Asn Tyr Arg Phe His Pro Gly Gln Ile Arg Ile Ile Asp 280 285 290 gat tta cta ctc aaa cga ttt ggc caa tca cac atc gat gcc acc gtc 1027 Asp Leu Leu Leu Lys Arg Phe Gly Gln Ser His Ile Asp Ala Thr Val 295 300 305 gcc acc gac tcc caa cca ctc aac gcc aaa cgc cac agg cag cta aaa 1075 Ala Thr Asp Ser Gln Pro Leu Asn Ala Lys Arg His Arg Gln Leu Lys 310 315 320 325 cgc aag cta gag ctc atg acc caa gct cat ctt gtg gaa cca cca aac 1123 Arg Lys Leu Glu Leu Met Thr Gln Ala His Leu Val Glu Pro Pro Asn 330 335 340 taaagttccc ccaaagttag ccc 1146 <210> 1054 <211> 341 <212> PRT <213> Corynebacterium glutamicum <400> 1054 Met Ser Asp Asn Thr Leu Ser Gln Phe Gly Ser Tyr Tyr His Glu Phe 1 5 10 15 Arg Arg Ala His Pro Met Ala Asp Val Glu Phe Leu Leu Ala Ile Glu 20 25 30 Glu Leu Leu Thr Asp Gly Gly Val Thr Phe Asp Arg Val Thr Thr Arg 35 40 45 Ile Lys Glu Trp Ser Ser Leu Lys Ala Lys Ala Arg Lys Arg Arg Asn 50 55 60 Asp Gly Ser Leu Ile Tyr Pro Asp Pro Arg Lys Asp Ile His Asp Met 65 70 75 80 Ile Gly Val Arg Ile Thr Thr Tyr His Ser Thr Glu Ile Pro Val Ala 85 90 95 Leu Lys Val Leu Gln Asp Ser Phe Ile Val His Lys Ser Val Asp Lys 100 105 110 Ala Ala Glu Thr Arg Ile Ser Gly Gly Phe Gly Tyr Gly Ser His His 115 120 125 Leu Ile Leu Glu Val Asp Asp Thr Ser Asp Asp Leu Gln Asp Tyr Lys 130 135 140 Gly Leu Val Phe Glu Val Gln Val Arg Thr Val Leu Gln His Ala Trp 145 150 155 160 Ala Glu Phe Glu His Asp Ile Arg Tyr Lys Arg Ala Asp Val Ser Asn 165 170 175 Pro Glu Asp Phe Ser Ala Glu Val Asp Arg Met Phe Thr Leu Ala Ala 180 185 190 Gly Leu Ile Glu Leu Ala Asp Gln Gln Phe Asp Gln Ile Ala Ala Leu 195 200 205 Lys Glu Thr Ser Arg Val Ala Asp Glu Ser Val Glu Leu Thr Ala Glu 210 215 220 Thr Leu Pro Gly Val Leu Ala Met Leu Ile Gly Asn Arg Phe Pro Arg 225 230 235 240 Pro Arg Ser Thr Asn Tyr Arg Phe Leu Glu Asp Ile Leu Val Ala Asn 245 250 255 Ser Ile Thr Ser Val Val Gln Leu Arg Glu Leu Leu Asn Pro Thr Asp 260 265 270 Ile Glu Val Leu Leu Lys Val Met Asn Tyr Arg Phe His Pro Gly Gln 275 280 285 Ile Arg Ile Ile Asp Asp Leu Leu Leu Lys Arg Phe Gly Gln Ser His 290 295 300 Ile Asp Ala Thr Val Ala Thr Asp Ser Gln Pro Leu Asn Ala Lys Arg 305 310 315 320 His Arg Gln Leu Lys Arg Lys Leu Glu Leu Met Thr Gln Ala His Leu 325 330 335 Val Glu Pro Pro Asn 340 <210> 1055 <211> 1234 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1234) <223> RXN02008 <400> 1055 tactggtcta tctatcaaaa gatgatcgtt cgcggtcgtg attttgacga tatttttgat 60 cttgttggca tccgcatcct ggtagacaac gtgaacaact gtg tac gcc gcc atc 115 Val Tyr Ala Ala Ile 1 5 ggt gtc gtg cac tcc ctg ttc aat gct ctg cct ggc cga ttc aaa gac 163 Gly Val Val His Ser Leu Phe Asn Ala Leu Pro Gly Arg Phe Lys Asp 10 15 20 tat att tca gcc ccg cgc ttc ggt gtc tac caa tcc ctg cac acc acc 211 Tyr Ile Ser Ala Pro Arg Phe Gly Val Tyr Gln Ser Leu His Thr Thr 25 30 35 gtg atg gga cct ggc ggt aag cct ctg gaa gtt cag gca cgt acc cac 259 Val Met Gly Pro Gly Gly Lys Pro Leu Glu Val Gln Ala Arg Thr His 40 45 50 gac atg cac tac aac gcc gaa ttc ggc att gca gcg cac tgg cga tac 307 Asp Met His Tyr Asn Ala Glu Phe Gly Ile Ala Ala His Trp Arg Tyr 55 60 65 aaa gaa acc aaa ggc agc cac agt ggc gag caa gcc gaa gtg gat caa 355 Lys Glu Thr Lys Gly Ser His Ser Gly Glu Gln Ala Glu Val Asp Gln 70 75 80 85 atg gcg tgg atg cgc caa ctt ctg gac tgg caa aaa gaa gca gcc gac 403 Met Ala Trp Met Arg Gln Leu Leu Asp Trp Gln Lys Glu Ala Ala Asp 90 95 100 ccc aac gag ttc ctg gac agc ctg cgc tac gat ctg act tcc aag cag 451 Pro Asn Glu Phe Leu Asp Ser Leu Arg Tyr Asp Leu Thr Ser Lys Gln 105 110 115 atc ttc gtg ttc aca ccc aaa ggt gat gtg gtc aac ctg ccg gtg aac 499 Ile Phe Val Phe Thr Pro Lys Gly Asp Val Val Asn Leu Pro Val Asn 120 125 130 tcc acc ccg gtg gac ttc gcc tac gcg gtg cac acc gaa gtg ggg cac 547 Ser Thr Pro Val Asp Phe Ala Tyr Ala Val His Thr Glu Val Gly His 135 140 145 cgc tgc atc ggc gcc aaa atc aac ggc aaa ctg gtc gct ttg gaa acg 595 Arg Cys Ile Gly Ala Lys Ile Asn Gly Lys Leu Val Ala Leu Glu Thr 150 155 160 165 aaa ctc aaa tcc ggc gat cgt gtt gaa gtc ttt acc tcc aag gac caa 643 Lys Leu Lys Ser Gly Asp Arg Val Glu Val Phe Thr Ser Lys Asp Gln 170 175 180 aac gct ggc cca agt agg gga tgg caa gaa ttt gtt gtc tca cct cgt 691 Asn Ala Gly Pro Ser Arg Gly Trp Gln Glu Phe Val Val Ser Pro Arg 185 190 195 gca aag gcc aag att cgc cag tgg ttt gcc aag gaa cga cgc gaa gaa 739 Ala Lys Ala Lys Ile Arg Gln Trp Phe Ala Lys Glu Arg Arg Glu Glu 200 205 210 tac cta gaa gcc gga cgc gat gcg ctg gca gca gtt att cag cgt ggc 787 Tyr Leu Glu Ala Gly Arg Asp Ala Leu Ala Ala Val Ile Gln Arg Gly 215 220 225 ggc ctg cca atg cac cgc ttg ttc acc gcg tcc tcc atg aag acg gtg 835 Gly Leu Pro Met His Arg Leu Phe Thr Ala Ser Ser Met Lys Thr Val 230 235 240 245 gca aca gag ctg cac tac cca gat gta gat gcg ctc tac aca gcc atc 883 Ala Thr Glu Leu His Tyr Pro Asp Val Asp Ala Leu Tyr Thr Ala Ile 250 255 260 ggc tcc ggt tct gta tct gcg caa cac gta gtc aac cgt ctc atg gct 931 Gly Ser Gly Ser Val Ser Ala Gln His Val Val Asn Arg Leu Met Ala 265 270 275 atc ttt ggt gac gaa gaa gat gcc gaa gac gca ttg gtt gca cgc acc 979 Ile Phe Gly Asp Glu Glu Asp Ala Glu Asp Ala Leu Val Ala Arg Thr 280 285 290 cca ttc agc gag ctg gtc aac tcc cgt gcc acc acg gaa agc agc acc 1027 Pro Phe Ser Glu Leu Val Asn Ser Arg Ala Thr Thr Glu Ser Ser Thr 295 300 305 ggc atc ctg gtc gaa ggc agc cca gat gtc atg gct aag ctc gct aaa 1075 Gly Ile Leu Val Glu Gly Ser Pro Asp Val Met Ala Lys Leu Ala Lys 310 315 320 325 tgc tgt atg cca gtg cca gga gat gaa atc ttt gga ttc gtc acc cgt 1123 Cys Cys Met Pro Val Pro Gly Asp Glu Ile Phe Gly Phe Val Thr Arg 330 335 340 ggt ggc ggt gtc tcc gta cac cga aca gac tgc acg aat gtg gaa aag 1171 Gly Gly Gly Val Ser Val His Arg Thr Asp Cys Thr Asn Val Glu Lys 345 350 355 ctc aaa gaa gag cca gaa cgc att gtc tcc gtc tcc tgg gct tcg gaa 1219 Leu Lys Glu Glu Pro Glu Arg Ile Val Ser Val Ser Trp Ala Ser Glu 360 365 370 ggt caa ggt tca gta 1234 Gly Gln Gly Ser Val 375 <210> 1056 <211> 378 <212> PRT <213> Corynebacterium glutamicum <400> 1056 Val Tyr Ala Ala Ile Gly Val Val His Ser Leu Phe Asn Ala Leu Pro 1 5 10 15 Gly Arg Phe Lys Asp Tyr Ile Ser Ala Pro Arg Phe Gly Val Tyr Gln 20 25 30 Ser Leu His Thr Thr Val Met Gly Pro Gly Gly Lys Pro Leu Glu Val 35 40 45 Gln Ala Arg Thr His Asp Met His Tyr Asn Ala Glu Phe Gly Ile Ala 50 55 60 Ala His Trp Arg Tyr Lys Glu Thr Lys Gly Ser His Ser Gly Glu Gln 65 70 75 80 Ala Glu Val Asp Gln Met Ala Trp Met Arg Gln Leu Leu Asp Trp Gln 85 90 95 Lys Glu Ala Ala Asp Pro Asn Glu Phe Leu Asp Ser Leu Arg Tyr Asp 100 105 110 Leu Thr Ser Lys Gln Ile Phe Val Phe Thr Pro Lys Gly Asp Val Val 115 120 125 Asn Leu Pro Val Asn Ser Thr Pro Val Asp Phe Ala Tyr Ala Val His 130 135 140 Thr Glu Val Gly His Arg Cys Ile Gly Ala Lys Ile Asn Gly Lys Leu 145 150 155 160 Val Ala Leu Glu Thr Lys Leu Lys Ser Gly Asp Arg Val Glu Val Phe 165 170 175 Thr Ser Lys Asp Gln Asn Ala Gly Pro Ser Arg Gly Trp Gln Glu Phe 180 185 190 Val Val Ser Pro Arg Ala Lys Ala Lys Ile Arg Gln Trp Phe Ala Lys 195 200 205 Glu Arg Arg Glu Glu Tyr Leu Glu Ala Gly Arg Asp Ala Leu Ala Ala 210 215 220 Val Ile Gln Arg Gly Gly Leu Pro Met His Arg Leu Phe Thr Ala Ser 225 230 235 240 Ser Met Lys Thr Val Ala Thr Glu Leu His Tyr Pro Asp Val Asp Ala 245 250 255 Leu Tyr Thr Ala Ile Gly Ser Gly Ser Val Ser Ala Gln His Val Val 260 265 270 Asn Arg Leu Met Ala Ile Phe Gly Asp Glu Glu Asp Ala Glu Asp Ala 275 280 285 Leu Val Ala Arg Thr Pro Phe Ser Glu Leu Val Asn Ser Arg Ala Thr 290 295 300 Thr Glu Ser Ser Thr Gly Ile Leu Val Glu Gly Ser Pro Asp Val Met 305 310 315 320 Ala Lys Leu Ala Lys Cys Cys Met Pro Val Pro Gly Asp Glu Ile Phe 325 330 335 Gly Phe Val Thr Arg Gly Gly Gly Val Ser Val His Arg Thr Asp Cys 340 345 350 Thr Asn Val Glu Lys Leu Lys Glu Glu Pro Glu Arg Ile Val Ser Val 355 360 365 Ser Trp Ala Ser Glu Gly Gln Gly Ser Val 370 375 <210> 1057 <211> 1059 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1036) <223> RXN01940 <400> 1057 ccagaatcaa tcaccgatac agtggcagcc aaagtccagg ctgaagaagc cgctcaagcc 60 gccagctaaa tccacaaact gaactaagga gttttaccct atg acc acc aag atc 115 Met Thr Thr Lys Ile 1 5 atc ctc gac tgc gat cca gga cac gac gac gct gta gcc atg ctg ctc 163 Ile Leu Asp Cys Asp Pro Gly His Asp Asp Ala Val Ala Met Leu Leu 10 15 20 gca gcc ggc agc cca gaa att gaa ctg ctt gga atc acc acg gtc ggc 211 Ala Ala Gly Ser Pro Glu Ile Glu Leu Leu Gly Ile Thr Thr Val Gly 25 30 35 ggc aac cag acc ttg gac aag gtc acc cac aat acg cag gtc gta gcc 259 Gly Asn Gln Thr Leu Asp Lys Val Thr His Asn Thr Gln Val Val Ala 40 45 50 acc atc gct gat atc aat gcg ccc atc tac cgc ggt gtc acc cga cca 307 Thr Ile Ala Asp Ile Asn Ala Pro Ile Tyr Arg Gly Val Thr Arg Pro 55 60 65 ttg gtg cgc ccc gtt gag gta gcc gaa gat atc cac ggc gat acc ggc 355 Leu Val Arg Pro Val Glu Val Ala Glu Asp Ile His Gly Asp Thr Gly 70 75 80 85 atg gaa atc cac aag tac gaa ctg cct gaa cca acc aag cag gta gaa 403 Met Glu Ile His Lys Tyr Glu Leu Pro Glu Pro Thr Lys Gln Val Glu 90 95 100 gac acc cac gcg gtg gat ttc atc atc gat acc atc atg aat aac gag 451 Asp Thr His Ala Val Asp Phe Ile Ile Asp Thr Ile Met Asn Asn Glu 105 110 115 ccc ggc agc gta gcg ctg gtt ccc acc gga cca ctg acc aac atc gcg 499 Pro Gly Ser Val Ala Leu Val Pro Thr Gly Pro Leu Thr Asn Ile Ala 120 125 130 ctg gca gtc cgg aaa gaa cca cgc atc gcc gag cga gtc aag gaa gtt 547 Leu Ala Val Arg Lys Glu Pro Arg Ile Ala Glu Arg Val Lys Glu Val 135 140 145 gtc ctc atg ggc ggg ggc tac cac gta gga aac tgg acc gcc gta gct 595 Val Leu Met Gly Gly Gly Tyr His Val Gly Asn Trp Thr Ala Val Ala 150 155 160 165 gaa ttc aac atc aag atc gac ccc gaa gca gcc cac atc gta ttc aac 643 Glu Phe Asn Ile Lys Ile Asp Pro Glu Ala Ala His Ile Val Phe Asn 170 175 180 gaa aag tgg cca ctg act atg gtc ggc ctc gac ctt acc cac cag gcg 691 Glu Lys Trp Pro Leu Thr Met Val Gly Leu Asp Leu Thr His Gln Ala 185 190 195 ctc gca aca cct gag atc gaa gcc aag ttc aac gag ctg ggc acc gac 739 Leu Ala Thr Pro Glu Ile Glu Ala Lys Phe Asn Glu Leu Gly Thr Asp 200 205 210 gtc gcc gac ttc gtc gtc gcg ctt ttc gac gct ttc cgc aag aat tac 787 Val Ala Asp Phe Val Val Ala Leu Phe Asp Ala Phe Arg Lys Asn Tyr 215 220 225 cag gac gca cag ggt ttt gat aac cca cca gta cac gac cct tgt gct 835 Gln Asp Ala Gln Gly Phe Asp Asn Pro Pro Val His Asp Pro Cys Ala 230 235 240 245 gtt gca tac ctt gtt gac cca acc gta ttc acc acc cgc aaa gca cca 883 Val Ala Tyr Leu Val Asp Pro Thr Val Phe Thr Thr Arg Lys Ala Pro 250 255 260 ctc gat gtg gag ctg tac ggc gca ctc acc aca ggc atg acc gtt gct 931 Leu Asp Val Glu Leu Tyr Gly Ala Leu Thr Thr Gly Met Thr Val Ala 265 270 275 gat ttc cgc gca ccg gct cca gca gat tgc acc acc caa gta gct gtt 979 Asp Phe Arg Ala Pro Ala Pro Ala Asp Cys Thr Thr Gln Val Ala Val 280 285 290 gac ctg gac ttt gat aaa ttc tgg aac atg gtg atc gat gca gta aag 1027 Asp Leu Asp Phe Asp Lys Phe Trp Asn Met Val Ile Asp Ala Val Lys 295 300 305 cgc atc gga tagacctgtt cacaaggttg tta 1059 Arg Ile Gly 310 <210> 1058 <211> 312 <212> PRT <213> Corynebacterium glutamicum <400> 1058 Met Thr Thr Lys Ile Ile Leu Asp Cys Asp Pro Gly His Asp Asp Ala 1 5 10 15 Val Ala Met Leu Leu Ala Ala Gly Ser Pro Glu Ile Glu Leu Leu Gly 20 25 30 Ile Thr Thr Val Gly Gly Asn Gln Thr Leu Asp Lys Val Thr His Asn 35 40 45 Thr Gln Val Val Ala Thr Ile Ala Asp Ile Asn Ala Pro Ile Tyr Arg 50 55 60 Gly Val Thr Arg Pro Leu Val Arg Pro Val Glu Val Ala Glu Asp Ile 65 70 75 80 His Gly Asp Thr Gly Met Glu Ile His Lys Tyr Glu Leu Pro Glu Pro 85 90 95 Thr Lys Gln Val Glu Asp Thr His Ala Val Asp Phe Ile Ile Asp Thr 100 105 110 Ile Met Asn Asn Glu Pro Gly Ser Val Ala Leu Val Pro Thr Gly Pro 115 120 125 Leu Thr Asn Ile Ala Leu Ala Val Arg Lys Glu Pro Arg Ile Ala Glu 130 135 140 Arg Val Lys Glu Val Val Leu Met Gly Gly Gly Tyr His Val Gly Asn 145 150 155 160 Trp Thr Ala Val Ala Glu Phe Asn Ile Lys Ile Asp Pro Glu Ala Ala 165 170 175 His Ile Val Phe Asn Glu Lys Trp Pro Leu Thr Met Val Gly Leu Asp 180 185 190 Leu Thr His Gln Ala Leu Ala Thr Pro Glu Ile Glu Ala Lys Phe Asn 195 200 205 Glu Leu Gly Thr Asp Val Ala Asp Phe Val Val Ala Leu Phe Asp Ala 210 215 220 Phe Arg Lys Asn Tyr Gln Asp Ala Gln Gly Phe Asp Asn Pro Pro Val 225 230 235 240 His Asp Pro Cys Ala Val Ala Tyr Leu Val Asp Pro Thr Val Phe Thr 245 250 255 Thr Arg Lys Ala Pro Leu Asp Val Glu Leu Tyr Gly Ala Leu Thr Thr 260 265 270 Gly Met Thr Val Ala Asp Phe Arg Ala Pro Ala Pro Ala Asp Cys Thr 275 280 285 Thr Gln Val Ala Val Asp Leu Asp Phe Asp Lys Phe Trp Asn Met Val 290 295 300 Ile Asp Ala Val Lys Arg Ile Gly 305 310 <210> 1059 <211> 602 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(579) <223> FRXA01940 <400> 1059 aga gta acg ctt gtt tcc acc ggg cca ctg acc aac atc gcg ctg gca 48 Arg Val Thr Leu Val Ser Thr Gly Pro Leu Thr Asn Ile Ala Leu Ala 1 5 10 15 gtc cgg aaa gaa cca cgc atc gcc gag cga gtc aag gaa gtt gtc ctc 96 Val Arg Lys Glu Pro Arg Ile Ala Glu Arg Val Lys Glu Val Val Leu 20 25 30 atg ggc ggg ggc tac cac gta gga aac tgg acc gcc gta gct gaa ttc 144 Met Gly Gly Gly Tyr His Val Gly Asn Trp Thr Ala Val Ala Glu Phe 35 40 45 aac atc aag atc gac ccc gaa gca gcc cac atc gta ttc aac gaa aag 192 Asn Ile Lys Ile Asp Pro Glu Ala Ala His Ile Val Phe Asn Glu Lys 50 55 60 tgg cca ctg act atg gtc ggc ctc gac ctt acc cac cag gcg ctc gca 240 Trp Pro Leu Thr Met Val Gly Leu Asp Leu Thr His Gln Ala Leu Ala 65 70 75 80 aca cct gag atc gaa gcc aag ttc aac gag ctg ggc acc gac gtc gcc 288 Thr Pro Glu Ile Glu Ala Lys Phe Asn Glu Leu Gly Thr Asp Val Ala 85 90 95 gac ttc gtc gtc gcg ctt ttc gac gct ttc cgc aag aat tac cag gac 336 Asp Phe Val Val Ala Leu Phe Asp Ala Phe Arg Lys Asn Tyr Gln Asp 100 105 110 gca cag ggt ttt gat aac cca cca gta cac gac cct tgt gct gtt gca 384 Ala Gln Gly Phe Asp Asn Pro Pro Val His Asp Pro Cys Ala Val Ala 115 120 125 tac ctt gtt gac cca acc gta ttc acc acc cgc aaa gca cca ctc gat 432 Tyr Leu Val Asp Pro Thr Val Phe Thr Thr Arg Lys Ala Pro Leu Asp 130 135 140 gtg gag ctg tac ggc gca ctc acc aca ggc atg acc gtt gct gat ttc 480 Val Glu Leu Tyr Gly Ala Leu Thr Thr Gly Met Thr Val Ala Asp Phe 145 150 155 160 cgc gca ccg gct cca gca gat tgc acc acc caa gta gct gtt gac ctg 528 Arg Ala Pro Ala Pro Ala Asp Cys Thr Thr Gln Val Ala Val Asp Leu 165 170 175 gac ttt gat aaa ttc tgg aac atg gtg atc gat gca gta aag cgc atc 576 Asp Phe Asp Lys Phe Trp Asn Met Val Ile Asp Ala Val Lys Arg Ile 180 185 190 gga tagacctgtt cacaaggttg tta 602 Gly <210> 1060 <211> 193 <212> PRT <213> Corynebacterium glutamicum <400> 1060 Arg Val Thr Leu Val Ser Thr Gly Pro Leu Thr Asn Ile Ala Leu Ala 1 5 10 15 Val Arg Lys Glu Pro Arg Ile Ala Glu Arg Val Lys Glu Val Val Leu 20 25 30 Met Gly Gly Gly Tyr His Val Gly Asn Trp Thr Ala Val Ala Glu Phe 35 40 45 Asn Ile Lys Ile Asp Pro Glu Ala Ala His Ile Val Phe Asn Glu Lys 50 55 60 Trp Pro Leu Thr Met Val Gly Leu Asp Leu Thr His Gln Ala Leu Ala 65 70 75 80 Thr Pro Glu Ile Glu Ala Lys Phe Asn Glu Leu Gly Thr Asp Val Ala 85 90 95 Asp Phe Val Val Ala Leu Phe Asp Ala Phe Arg Lys Asn Tyr Gln Asp 100 105 110 Ala Gln Gly Phe Asp Asn Pro Pro Val His Asp Pro Cys Ala Val Ala 115 120 125 Tyr Leu Val Asp Pro Thr Val Phe Thr Thr Arg Lys Ala Pro Leu Asp 130 135 140 Val Glu Leu Tyr Gly Ala Leu Thr Thr Gly Met Thr Val Ala Asp Phe 145 150 155 160 Arg Ala Pro Ala Pro Ala Asp Cys Thr Thr Gln Val Ala Val Asp Leu 165 170 175 Asp Phe Asp Lys Phe Trp Asn Met Val Ile Asp Ala Val Lys Arg Ile 180 185 190 Gly <210> 1061 <211> 1026 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1003) <223> RXA02559 <400> 1061 ttagtcctct atggcagcaa gcctgccaga ggagcctatc cagcactaga ccccaactag 60 aacccaaccc caaaaccaga aaacactaag ctcgtgagac atg att cct gtt ctc 115 Met Ile Pro Val Leu 1 5 atc gac tgc gac acc ggc atc gac gac gcc ctc gcc ctg atc tac ctg 163 Ile Asp Cys Asp Thr Gly Ile Asp Asp Ala Leu Ala Leu Ile Tyr Leu 10 15 20 gtt gct ttg cat aaa cgt ggt gaa atc caa ctt ttt gga gca acg acc 211 Val Ala Leu His Lys Arg Gly Glu Ile Gln Leu Phe Gly Ala Thr Thr 25 30 35 acc gca gga aat gtt gat gtg aaa caa acc gcc atc aat acc agg tgg 259 Thr Ala Gly Asn Val Asp Val Lys Gln Thr Ala Ile Asn Thr Arg Trp 40 45 50 gtg ttg gat cag tgt gga tta gcg gac atc ccg gtc ctc gca gga caa 307 Val Leu Asp Gln Cys Gly Leu Ala Asp Ile Pro Val Leu Ala Gly Gln 55 60 65 cct gaa cca aag cac gtg ccg cta gtg act act cca gaa aca cac ggc 355 Pro Glu Pro Lys His Val Pro Leu Val Thr Thr Pro Glu Thr His Gly 70 75 80 85 gac cat ggc ctt ggt tat ata aac cca ggt cac gtc gaa att cca gaa 403 Asp His Gly Leu Gly Tyr Ile Asn Pro Gly His Val Glu Ile Pro Glu 90 95 100 ggt gac tgg aag cag ctg tgg aaa gaa cac ctc agt aac cca gaa act 451 Gly Asp Trp Lys Gln Leu Trp Lys Glu His Leu Ser Asn Pro Glu Thr 105 110 115 aag ctg att gtc acc ggg ccc gcc acc aac ctt gcg gaa ttc ggg cca 499 Lys Leu Ile Val Thr Gly Pro Ala Thr Asn Leu Ala Glu Phe Gly Pro 120 125 130 gtg gaa aac gtc acg ctg atg ggt ggc acc tac ctt tat cca ggc aac 547 Val Glu Asn Val Thr Leu Met Gly Gly Thr Tyr Leu Tyr Pro Gly Asn 135 140 145 acc act cca acg gca gaa tgg aat acc tgg gtt gat cca cac gga gct 595 Thr Thr Pro Thr Ala Glu Trp Asn Thr Trp Val Asp Pro His Gly Ala 150 155 160 165 aaa gaa gca ttc gcg gca gcc caa aag ccc att acg gtg tgt tcc ttg 643 Lys Glu Ala Phe Ala Ala Ala Gln Lys Pro Ile Thr Val Cys Ser Leu 170 175 180 ggc gtg acc gag cag ttt acg ctg aac ccg gac atc ctt tct aca ctt 691 Gly Val Thr Glu Gln Phe Thr Leu Asn Pro Asp Ile Leu Ser Thr Leu 185 190 195 atc aac acg ctt ggc agc caa ccc atc gca gag cat tta cct gag atg 739 Ile Asn Thr Leu Gly Ser Gln Pro Ile Ala Glu His Leu Pro Glu Met 200 205 210 ctg cgc ttt tac ttt gaa ttt cac gaa gtg cag ggc gaa ggt tac ctt 787 Leu Arg Phe Tyr Phe Glu Phe His Glu Val Gln Gly Glu Gly Tyr Leu 215 220 225 gct caa att cat gac ctg ctg acc tgc atg att gcc ttg gat aaa atc 835 Ala Gln Ile His Asp Leu Leu Thr Cys Met Ile Ala Leu Asp Lys Ile 230 235 240 245 cca ttt tca ggc cgt gaa gta acc gtg gac gtg gag gct gat tcg ccc 883 Pro Phe Ser Gly Arg Glu Val Thr Val Asp Val Glu Ala Asp Ser Pro 250 255 260 ttg atg cgt ggc acc act gtt gca gat att cgc gga cat tgg ggc aag 931 Leu Met Arg Gly Thr Thr Val Ala Asp Ile Arg Gly His Trp Gly Lys 265 270 275 cca gct aac gca ttt ctt gtg gaa acc gca gac att gag gcc gcc cac 979 Pro Ala Asn Ala Phe Leu Val Glu Thr Ala Asp Ile Glu Ala Ala His 280 285 290 gcg gaa ctt cta aga gca gtg gaa tgaaataatc cggtgctgat gca 1026 Ala Glu Leu Leu Arg Ala Val Glu 295 300 <210> 1062 <211> 301 <212> PRT <213> Corynebacterium glutamicum <400> 1062 Met Ile Pro Val Leu Ile Asp Cys Asp Thr Gly Ile Asp Asp Ala Leu 1 5 10 15 Ala Leu Ile Tyr Leu Val Ala Leu His Lys Arg Gly Glu Ile Gln Leu 20 25 30 Phe Gly Ala Thr Thr Thr Ala Gly Asn Val Asp Val Lys Gln Thr Ala 35 40 45 Ile Asn Thr Arg Trp Val Leu Asp Gln Cys Gly Leu Ala Asp Ile Pro 50 55 60 Val Leu Ala Gly Gln Pro Glu Pro Lys His Val Pro Leu Val Thr Thr 65 70 75 80 Pro Glu Thr His Gly Asp His Gly Leu Gly Tyr Ile Asn Pro Gly His 85 90 95 Val Glu Ile Pro Glu Gly Asp Trp Lys Gln Leu Trp Lys Glu His Leu 100 105 110 Ser Asn Pro Glu Thr Lys Leu Ile Val Thr Gly Pro Ala Thr Asn Leu 115 120 125 Ala Glu Phe Gly Pro Val Glu Asn Val Thr Leu Met Gly Gly Thr Tyr 130 135 140 Leu Tyr Pro Gly Asn Thr Thr Pro Thr Ala Glu Trp Asn Thr Trp Val 145 150 155 160 Asp Pro His Gly Ala Lys Glu Ala Phe Ala Ala Ala Gln Lys Pro Ile 165 170 175 Thr Val Cys Ser Leu Gly Val Thr Glu Gln Phe Thr Leu Asn Pro Asp 180 185 190 Ile Leu Ser Thr Leu Ile Asn Thr Leu Gly Ser Gln Pro Ile Ala Glu 195 200 205 His Leu Pro Glu Met Leu Arg Phe Tyr Phe Glu Phe His Glu Val Gln 210 215 220 Gly Glu Gly Tyr Leu Ala Gln Ile His Asp Leu Leu Thr Cys Met Ile 225 230 235 240 Ala Leu Asp Lys Ile Pro Phe Ser Gly Arg Glu Val Thr Val Asp Val 245 250 255 Glu Ala Asp Ser Pro Leu Met Arg Gly Thr Thr Val Ala Asp Ile Arg 260 265 270 Gly His Trp Gly Lys Pro Ala Asn Ala Phe Leu Val Glu Thr Ala Asp 275 280 285 Ile Glu Ala Ala His Ala Glu Leu Leu Arg Ala Val Glu 290 295 300 <210> 1063 <211> 1050 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1027) <223> RXA02497 <400> 1063 tcgatgccgc cgctggcgaa gactcgggga aacctaaaaa taccgaagaa gaatttgacc 60 gattcacact ttgccaccct agaccgtcta acctttaggt gtg aga tta ggt gta 115 Val Arg Leu Gly Val 1 5 tta gat gtg ggc agc aat act gtc cac cta gtt gca gta gac gcg cgt 163 Leu Asp Val Gly Ser Asn Thr Val His Leu Val Ala Val Asp Ala Arg 10 15 20 ccc ggt gga cac ccc acc ccg atg agc aat tgg cgt acc cca ctg cgc 211 Pro Gly Gly His Pro Thr Pro Met Ser Asn Trp Arg Thr Pro Leu Arg 25 30 35 ctt gtt gag ctt ctt gat gac tcc ggg gcg atc tcc gaa aag ggc atc 259 Leu Val Glu Leu Leu Asp Asp Ser Gly Ala Ile Ser Glu Lys Gly Ile 40 45 50 aac aaa ctc acc tca gca gtc ggg gaa gca gca gac cta gcg aaa acg 307 Asn Lys Leu Thr Ser Ala Val Gly Glu Ala Ala Asp Leu Ala Lys Thr 55 60 65 ctc ggc tgc gct gaa ctg atg cca ttt gct aca tcg gca gtc cgc tcc 355 Leu Gly Cys Ala Glu Leu Met Pro Phe Ala Thr Ser Ala Val Arg Ser 70 75 80 85 gcc acc aac agc gag gca gtg ctc gac cac gtg gag aag gaa acc ggc 403 Ala Thr Asn Ser Glu Ala Val Leu Asp His Val Glu Lys Glu Thr Gly 90 95 100 gtc cgc ctg tcc atc ctt tcc ggt gaa gac gaa gca cgc caa act ttc 451 Val Arg Leu Ser Ile Leu Ser Gly Glu Asp Glu Ala Arg Gln Thr Phe 105 110 115 ctc gca gtt cga cgt tgg tat gga tgg tcc gca ggg cgc ata act aac 499 Leu Ala Val Arg Arg Trp Tyr Gly Trp Ser Ala Gly Arg Ile Thr Asn 120 125 130 ctc gac atc ggt ggc ggc tcc ctg gaa cta tcc tcc gga acc gac gaa 547 Leu Asp Ile Gly Gly Gly Ser Leu Glu Leu Ser Ser Gly Thr Asp Glu 135 140 145 tcc cca gac ctc gcg ttc tca ctg gat ctg ggt gcg ggc cgc ttg acc 595 Ser Pro Asp Leu Ala Phe Ser Leu Asp Leu Gly Ala Gly Arg Leu Thr 150 155 160 165 cac aac tgg ttc gac acc gat cca ccg gca cgt aag aaa atc aac ctc 643 His Asn Trp Phe Asp Thr Asp Pro Pro Ala Arg Lys Lys Ile Asn Leu 170 175 180 ctg cgc gat tat atc gat gcg gaa ctt gca gaa ccc gcc cgc cag atg 691 Leu Arg Asp Tyr Ile Asp Ala Glu Leu Ala Glu Pro Ala Arg Gln Met 185 190 195 cgc acc cta ggg ccc gcg cgc ctg gca gtg gga aca tcc aaa act ttc 739 Arg Thr Leu Gly Pro Ala Arg Leu Ala Val Gly Thr Ser Lys Thr Phe 200 205 210 cgc acc ctg gca cga ctg act ggt gct gcg ccc tca tcc gca gga cca 787 Arg Thr Leu Ala Arg Leu Thr Gly Ala Ala Pro Ser Ser Ala Gly Pro 215 220 225 cac gtc acc cga acc ctc acc gcg ccg ggt ctg cgc cag ctg atc gca 835 His Val Thr Arg Thr Leu Thr Ala Pro Gly Leu Arg Gln Leu Ile Ala 230 235 240 245 ttt atc tca cga atg act gcg gcg gac cgc gct gag ctg gaa ggt atc 883 Phe Ile Ser Arg Met Thr Ala Ala Asp Arg Ala Glu Leu Glu Gly Ile 250 255 260 agc tcg gat cgg tca cat cag atc gtg gca ggt gcg cta gtt gcg gaa 931 Ser Ser Asp Arg Ser His Gln Ile Val Ala Gly Ala Leu Val Ala Glu 265 270 275 gct gcg atg cgt gcg ttg gat att gac aag gta gaa att tgt ccg tgg 979 Ala Ala Met Arg Ala Leu Asp Ile Asp Lys Val Glu Ile Cys Pro Trp 280 285 290 gca ctt cgt gaa ggt gtg atc ctc acc agg atc gac aaa gga ctc gag 1027 Ala Leu Arg Glu Gly Val Ile Leu Thr Arg Ile Asp Lys Gly Leu Glu 295 300 305 taacatttac ccggaaagga gtt 1050 <210> 1064 <211> 309 <212> PRT <213> Corynebacterium glutamicum <400> 1064 Val Arg Leu Gly Val Leu Asp Val Gly Ser Asn Thr Val His Leu Val 1 5 10 15 Ala Val Asp Ala Arg Pro Gly Gly His Pro Thr Pro Met Ser Asn Trp 20 25 30 Arg Thr Pro Leu Arg Leu Val Glu Leu Leu Asp Asp Ser Gly Ala Ile 35 40 45 Ser Glu Lys Gly Ile Asn Lys Leu Thr Ser Ala Val Gly Glu Ala Ala 50 55 60 Asp Leu Ala Lys Thr Leu Gly Cys Ala Glu Leu Met Pro Phe Ala Thr 65 70 75 80 Ser Ala Val Arg Ser Ala Thr Asn Ser Glu Ala Val Leu Asp His Val 85 90 95 Glu Lys Glu Thr Gly Val Arg Leu Ser Ile Leu Ser Gly Glu Asp Glu 100 105 110 Ala Arg Gln Thr Phe Leu Ala Val Arg Arg Trp Tyr Gly Trp Ser Ala 115 120 125 Gly Arg Ile Thr Asn Leu Asp Ile Gly Gly Gly Ser Leu Glu Leu Ser 130 135 140 Ser Gly Thr Asp Glu Ser Pro Asp Leu Ala Phe Ser Leu Asp Leu Gly 145 150 155 160 Ala Gly Arg Leu Thr His Asn Trp Phe Asp Thr Asp Pro Pro Ala Arg 165 170 175 Lys Lys Ile Asn Leu Leu Arg Asp Tyr Ile Asp Ala Glu Leu Ala Glu 180 185 190 Pro Ala Arg Gln Met Arg Thr Leu Gly Pro Ala Arg Leu Ala Val Gly 195 200 205 Thr Ser Lys Thr Phe Arg Thr Leu Ala Arg Leu Thr Gly Ala Ala Pro 210 215 220 Ser Ser Ala Gly Pro His Val Thr Arg Thr Leu Thr Ala Pro Gly Leu 225 230 235 240 Arg Gln Leu Ile Ala Phe Ile Ser Arg Met Thr Ala Ala Asp Arg Ala 245 250 255 Glu Leu Glu Gly Ile Ser Ser Asp Arg Ser His Gln Ile Val Ala Gly 260 265 270 Ala Leu Val Ala Glu Ala Ala Met Arg Ala Leu Asp Ile Asp Lys Val 275 280 285 Glu Ile Cys Pro Trp Ala Leu Arg Glu Gly Val Ile Leu Thr Arg Ile 290 295 300 Asp Lys Gly Leu Glu 305 <210> 1065 <211> 2226 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2203) <223> RXN01079 <400> 1065 accttaaaac ttaatcaatc aatacaaagt tcacacctct tttgaaaggg acattccttt 60 gactgcatcg ggaaccaccg tcgtgccacg cggagaccag atg gac ttc cac gct 115 Met Asp Phe His Ala 1 5 ctt aac gcg ttg ctc aac ctt tac gat gac aac ggc aag atc cag ttt 163 Leu Asn Ala Leu Leu Asn Leu Tyr Asp Asp Asn Gly Lys Ile Gln Phe 10 15 20 gag aaa gac cgt gaa gct gca aac cag tac ttc ctg cag cac gtc aac 211 Glu Lys Asp Arg Glu Ala Ala Asn Gln Tyr Phe Leu Gln His Val Asn 25 30 35 cag aac acc gtc ttc ttc cac aac ctg cag gaa aag atc gac tac ctg 259 Gln Asn Thr Val Phe Phe His Asn Leu Gln Glu Lys Ile Asp Tyr Leu 40 45 50 gtt gaa aac aag tac tat gac cca atc gtt ctg gac aag tac gac ttc 307 Val Glu Asn Lys Tyr Tyr Asp Pro Ile Val Leu Asp Lys Tyr Asp Phe 55 60 65 cag ttc atc aag gac ctc ttc aag cgc gca tac gga ttc aag ttc cgc 355 Gln Phe Ile Lys Asp Leu Phe Lys Arg Ala Tyr Gly Phe Lys Phe Arg 70 75 80 85 ttc cag tcc ttc ctc ggt gca tac aag tac tac act tcc tac acc ctg 403 Phe Gln Ser Phe Leu Gly Ala Tyr Lys Tyr Tyr Thr Ser Tyr Thr Leu 90 95 100 aag acc ttc gac ggt cgc cgc tac ctc gag cgt ttc gaa gac cgt gtc 451 Lys Thr Phe Asp Gly Arg Arg Tyr Leu Glu Arg Phe Glu Asp Arg Val 105 110 115 tgc atg gtc gcc ctc acc ctc gct gac ggc gac cgc gca ttg gcc gag 499 Cys Met Val Ala Leu Thr Leu Ala Asp Gly Asp Arg Ala Leu Ala Glu 120 125 130 aac ctg gtc gat gag atc atg tct ggc cgt ttc caa cca gca acc cca 547 Asn Leu Val Asp Glu Ile Met Ser Gly Arg Phe Gln Pro Ala Thr Pro 135 140 145 acc ttc ctg aac tcc ggc aag gca cag cgc ggc gag cca gta tcc tgc 595 Thr Phe Leu Asn Ser Gly Lys Ala Gln Arg Gly Glu Pro Val Ser Cys 150 155 160 165 ttc ctc ctg cgt atc gaa gac aac atg gag tcc atc gga cgt tcc atc 643 Phe Leu Leu Arg Ile Glu Asp Asn Met Glu Ser Ile Gly Arg Ser Ile 170 175 180 aac tct gct ctt cag ctg tcc aag cgt ggc ggt ggc gta gcg ttg ctg 691 Asn Ser Ala Leu Gln Leu Ser Lys Arg Gly Gly Gly Val Ala Leu Leu 185 190 195 ctg tcc aac ctt cgt gaa gcc ggt gca ccg att aag aag att gaa aac 739 Leu Ser Asn Leu Arg Glu Ala Gly Ala Pro Ile Lys Lys Ile Glu Asn 200 205 210 cag tct tcc ggt gtt atc cca gtg atg aaa ctt ctg gaa gat gct ttc 787 Gln Ser Ser Gly Val Ile Pro Val Met Lys Leu Leu Glu Asp Ala Phe 215 220 225 tcc tac gct aac cag ctg ggt gct cgt cag ggt gca ggt gct gtg tac 835 Ser Tyr Ala Asn Gln Leu Gly Ala Arg Gln Gly Ala Gly Ala Val Tyr 230 235 240 245 ctc aac gct cac cac cca gat atc ctg tcc ttc ctg gat acc aag cgt 883 Leu Asn Ala His His Pro Asp Ile Leu Ser Phe Leu Asp Thr Lys Arg 250 255 260 gag aac gcc gat gag aag atc cgc atc aag acc ctg tcc ctg ggt gtt 931 Glu Asn Ala Asp Glu Lys Ile Arg Ile Lys Thr Leu Ser Leu Gly Val 265 270 275 gtg att ccg gac atc acc ttc gag ctg gct aag cgc aac gat gac atg 979 Val Ile Pro Asp Ile Thr Phe Glu Leu Ala Lys Arg Asn Asp Asp Met 280 285 290 tac ctg ttc tcc cca tac gat gtg gag cgc att tac ggc aag cct ttc 1027 Tyr Leu Phe Ser Pro Tyr Asp Val Glu Arg Ile Tyr Gly Lys Pro Phe 295 300 305 gca gac gtc tca atc acc gag cac tac gac gag atg gtg gat gat gac 1075 Ala Asp Val Ser Ile Thr Glu His Tyr Asp Glu Met Val Asp Asp Asp 310 315 320 325 cgc atc cgc aag acc aag atc aac gcg cgt cag ttc ttc cag acc ctg 1123 Arg Ile Arg Lys Thr Lys Ile Asn Ala Arg Gln Phe Phe Gln Thr Leu 330 335 340 gca gaa atc cag ttc gag tcc ggt tac cca tac atc atg tat gaa gac 1171 Ala Glu Ile Gln Phe Glu Ser Gly Tyr Pro Tyr Ile Met Tyr Glu Asp 345 350 355 acc gtg aat gca tcc aac cca atc gaa ggt cgc atc acc cac tca aac 1219 Thr Val Asn Ala Ser Asn Pro Ile Glu Gly Arg Ile Thr His Ser Asn 360 365 370 ctg tgc tct gag atc ctt cag gtg tcc acc cca tct gaa ttc aac gat 1267 Leu Cys Ser Glu Ile Leu Gln Val Ser Thr Pro Ser Glu Phe Asn Asp 375 380 385 gac ctg act tac gca gag gtc ggc gaa gac att tct tgt aac ttg ggt 1315 Asp Leu Thr Tyr Ala Glu Val Gly Glu Asp Ile Ser Cys Asn Leu Gly 390 395 400 405 tcc ctc aac gtt gca atg gct atg gat gca cca aac ttt gag aag acc 1363 Ser Leu Asn Val Ala Met Ala Met Asp Ala Pro Asn Phe Glu Lys Thr 410 415 420 atc gaa acc gaa atc cgc ggc tta act gca gtg cct gag cag acc agc 1411 Ile Glu Thr Glu Ile Arg Gly Leu Thr Ala Val Pro Glu Gln Thr Ser 425 430 435 atc gat tcc gtg cct tcc atc cgt aag ggc aac gaa gca gct cac gcc 1459 Ile Asp Ser Val Pro Ser Ile Arg Lys Gly Asn Glu Ala Ala His Ala 440 445 450 atc ggc ctt ggc cag atg aac ctt cac ggc tac ttc ggt cgc gag cac 1507 Ile Gly Leu Gly Gln Met Asn Leu His Gly Tyr Phe Gly Arg Glu His 455 460 465 atg cac tac ggc tcc gag gaa gcc ctg gac ttc acc aac gca tac ttt 1555 Met His Tyr Gly Ser Glu Glu Ala Leu Asp Phe Thr Asn Ala Tyr Phe 470 475 480 485 gct gcc gtg ctg tac cag tgc ctg cgt gca tcc aac cag atc gct act 1603 Ala Ala Val Leu Tyr Gln Cys Leu Arg Ala Ser Asn Gln Ile Ala Thr 490 495 500 gag cgt gga gag cgt ttc aag aac ttc gaa aac tcc aag tat gca acc 1651 Glu Arg Gly Glu Arg Phe Lys Asn Phe Glu Asn Ser Lys Tyr Ala Thr 505 510 515 ggt gag tac ttc gat gat ttc gat gca aac gac ttc gca cca aag tcc 1699 Gly Glu Tyr Phe Asp Asp Phe Asp Ala Asn Asp Phe Ala Pro Lys Ser 520 525 530 gac aag gtc aag gaa ctc ttt gcc aag tcg aac atc cac acc cca acc 1747 Asp Lys Val Lys Glu Leu Phe Ala Lys Ser Asn Ile His Thr Pro Thr 535 540 545 gtt gag gac tgg gct gcg ctg aag gcc gac gtg atg gag cac ggt ctg 1795 Val Glu Asp Trp Ala Ala Leu Lys Ala Asp Val Met Glu His Gly Leu 550 555 560 565 ttc aac cgt aac ctg caa gcg gtt cca cca acc ggt tcg atc tcc tac 1843 Phe Asn Arg Asn Leu Gln Ala Val Pro Pro Thr Gly Ser Ile Ser Tyr 570 575 580 atc aac aac tcc acc tcg tcg atc cac cca atc gca tcc aag att gag 1891 Ile Asn Asn Ser Thr Ser Ser Ile His Pro Ile Ala Ser Lys Ile Glu 585 590 595 atc cgc aag gaa ggc aag atc ggc cgc gtt tac tac cca gct cca cac 1939 Ile Arg Lys Glu Gly Lys Ile Gly Arg Val Tyr Tyr Pro Ala Pro His 600 605 610 atg gac aat gac aac ctt gag tac ttc gag gac gcc tac gaa atc ggc 1987 Met Asp Asn Asp Asn Leu Glu Tyr Phe Glu Asp Ala Tyr Glu Ile Gly 615 620 625 tac gag aag atc att gac acc tac gct gtg gca acc aag tac gtt gac 2035 Tyr Glu Lys Ile Ile Asp Thr Tyr Ala Val Ala Thr Lys Tyr Val Asp 630 635 640 645 cag ggc ctg tca ctg acc ttg ttc ttc aag gac act gcc acc acc cgt 2083 Gln Gly Leu Ser Leu Thr Leu Phe Phe Lys Asp Thr Ala Thr Thr Arg 650 655 660 gac atc aac cgt gcg cag atc tac gca tgg cgc aag ggc atc aag acc 2131 Asp Ile Asn Arg Ala Gln Ile Tyr Ala Trp Arg Lys Gly Ile Lys Thr 665 670 675 ttg tac tac att cgc ctg cgc cag gtt gct ctg gaa ggc act gaa gtt 2179 Leu Tyr Tyr Ile Arg Leu Arg Gln Val Ala Leu Glu Gly Thr Glu Val 680 685 690 gac ggc tgc gtc agc tgc atg ctg taaaagcact taaaaatatc ccc 2226 Asp Gly Cys Val Ser Cys Met Leu 695 700 <210> 1066 <211> 701 <212> PRT <213> Corynebacterium glutamicum <400> 1066 Met Asp Phe His Ala Leu Asn Ala Leu Leu Asn Leu Tyr Asp Asp Asn 1 5 10 15 Gly Lys Ile Gln Phe Glu Lys Asp Arg Glu Ala Ala Asn Gln Tyr Phe 20 25 30 Leu Gln His Val Asn Gln Asn Thr Val Phe Phe His Asn Leu Gln Glu 35 40 45 Lys Ile Asp Tyr Leu Val Glu Asn Lys Tyr Tyr Asp Pro Ile Val Leu 50 55 60 Asp Lys Tyr Asp Phe Gln Phe Ile Lys Asp Leu Phe Lys Arg Ala Tyr 65 70 75 80 Gly Phe Lys Phe Arg Phe Gln Ser Phe Leu Gly Ala Tyr Lys Tyr Tyr 85 90 95 Thr Ser Tyr Thr Leu Lys Thr Phe Asp Gly Arg Arg Tyr Leu Glu Arg 100 105 110 Phe Glu Asp Arg Val Cys Met Val Ala Leu Thr Leu Ala Asp Gly Asp 115 120 125 Arg Ala Leu Ala Glu Asn Leu Val Asp Glu Ile Met Ser Gly Arg Phe 130 135 140 Gln Pro Ala Thr Pro Thr Phe Leu Asn Ser Gly Lys Ala Gln Arg Gly 145 150 155 160 Glu Pro Val Ser Cys Phe Leu Leu Arg Ile Glu Asp Asn Met Glu Ser 165 170 175 Ile Gly Arg Ser Ile Asn Ser Ala Leu Gln Leu Ser Lys Arg Gly Gly 180 185 190 Gly Val Ala Leu Leu Leu Ser Asn Leu Arg Glu Ala Gly Ala Pro Ile 195 200 205 Lys Lys Ile Glu Asn Gln Ser Ser Gly Val Ile Pro Val Met Lys Leu 210 215 220 Leu Glu Asp Ala Phe Ser Tyr Ala Asn Gln Leu Gly Ala Arg Gln Gly 225 230 235 240 Ala Gly Ala Val Tyr Leu Asn Ala His His Pro Asp Ile Leu Ser Phe 245 250 255 Leu Asp Thr Lys Arg Glu Asn Ala Asp Glu Lys Ile Arg Ile Lys Thr 260 265 270 Leu Ser Leu Gly Val Val Ile Pro Asp Ile Thr Phe Glu Leu Ala Lys 275 280 285 Arg Asn Asp Asp Met Tyr Leu Phe Ser Pro Tyr Asp Val Glu Arg Ile 290 295 300 Tyr Gly Lys Pro Phe Ala Asp Val Ser Ile Thr Glu His Tyr Asp Glu 305 310 315 320 Met Val Asp Asp Asp Arg Ile Arg Lys Thr Lys Ile Asn Ala Arg Gln 325 330 335 Phe Phe Gln Thr Leu Ala Glu Ile Gln Phe Glu Ser Gly Tyr Pro Tyr 340 345 350 Ile Met Tyr Glu Asp Thr Val Asn Ala Ser Asn Pro Ile Glu Gly Arg 355 360 365 Ile Thr His Ser Asn Leu Cys Ser Glu Ile Leu Gln Val Ser Thr Pro 370 375 380 Ser Glu Phe Asn Asp Asp Leu Thr Tyr Ala Glu Val Gly Glu Asp Ile 385 390 395 400 Ser Cys Asn Leu Gly Ser Leu Asn Val Ala Met Ala Met Asp Ala Pro 405 410 415 Asn Phe Glu Lys Thr Ile Glu Thr Glu Ile Arg Gly Leu Thr Ala Val 420 425 430 Pro Glu Gln Thr Ser Ile Asp Ser Val Pro Ser Ile Arg Lys Gly Asn 435 440 445 Glu Ala Ala His Ala Ile Gly Leu Gly Gln Met Asn Leu His Gly Tyr 450 455 460 Phe Gly Arg Glu His Met His Tyr Gly Ser Glu Glu Ala Leu Asp Phe 465 470 475 480 Thr Asn Ala Tyr Phe Ala Ala Val Leu Tyr Gln Cys Leu Arg Ala Ser 485 490 495 Asn Gln Ile Ala Thr Glu Arg Gly Glu Arg Phe Lys Asn Phe Glu Asn 500 505 510 Ser Lys Tyr Ala Thr Gly Glu Tyr Phe Asp Asp Phe Asp Ala Asn Asp 515 520 525 Phe Ala Pro Lys Ser Asp Lys Val Lys Glu Leu Phe Ala Lys Ser Asn 530 535 540 Ile His Thr Pro Thr Val Glu Asp Trp Ala Ala Leu Lys Ala Asp Val 545 550 555 560 Met Glu His Gly Leu Phe Asn Arg Asn Leu Gln Ala Val Pro Pro Thr 565 570 575 Gly Ser Ile Ser Tyr Ile Asn Asn Ser Thr Ser Ser Ile His Pro Ile 580 585 590 Ala Ser Lys Ile Glu Ile Arg Lys Glu Gly Lys Ile Gly Arg Val Tyr 595 600 605 Tyr Pro Ala Pro His Met Asp Asn Asp Asn Leu Glu Tyr Phe Glu Asp 610 615 620 Ala Tyr Glu Ile Gly Tyr Glu Lys Ile Ile Asp Thr Tyr Ala Val Ala 625 630 635 640 Thr Lys Tyr Val Asp Gln Gly Leu Ser Leu Thr Leu Phe Phe Lys Asp 645 650 655 Thr Ala Thr Thr Arg Asp Ile Asn Arg Ala Gln Ile Tyr Ala Trp Arg 660 665 670 Lys Gly Ile Lys Thr Leu Tyr Tyr Ile Arg Leu Arg Gln Val Ala Leu 675 680 685 Glu Gly Thr Glu Val Asp Gly Cys Val Ser Cys Met Leu 690 695 700 <210> 1067 <211> 790 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(790) <223> FRXA01079 <400> 1067 accttaaaac ttaatcaatc aatacaaagt tcacacctct tttgaaaggg acattccttt 60 gactgcatcg ggaaccaccg tcgtgccacg cggagaccag atg gac ttc cac gct 115 Met Asp Phe His Ala 1 5 ctt aac gcg ttg ctc aac ctt tac gat gac aac ggc aag atc cag ttt 163 Leu Asn Ala Leu Leu Asn Leu Tyr Asp Asp Asn Gly Lys Ile Gln Phe 10 15 20 gag aaa gac cgt gaa gct gca aac cag tac ttc ctg cag cac gtc aac 211 Glu Lys Asp Arg Glu Ala Ala Asn Gln Tyr Phe Leu Gln His Val Asn 25 30 35 cag aac acc gtc ttc ttc cac aac ctg cag gaa aag atc gac tac ctg 259 Gln Asn Thr Val Phe Phe His Asn Leu Gln Glu Lys Ile Asp Tyr Leu 40 45 50 gtt gaa aac aag tac tat gac cca atc gtt ctg gac aag tac gac ttc 307 Val Glu Asn Lys Tyr Tyr Asp Pro Ile Val Leu Asp Lys Tyr Asp Phe 55 60 65 cag ttc atc aag gac ctc ttc aag cgc gca tac gga ttc aag ttc cgc 355 Gln Phe Ile Lys Asp Leu Phe Lys Arg Ala Tyr Gly Phe Lys Phe Arg 70 75 80 85 ttc cag tcc ttc ctc ggt gca tac aag tac tac act tcc tac acc ctg 403 Phe Gln Ser Phe Leu Gly Ala Tyr Lys Tyr Tyr Thr Ser Tyr Thr Leu 90 95 100 aag acc ttc gac ggt cgc cgc tac ctc gag cgt ttc gaa gac cgt gtc 451 Lys Thr Phe Asp Gly Arg Arg Tyr Leu Glu Arg Phe Glu Asp Arg Val 105 110 115 tgc atg gtc gcc ctc acc ctc gct gac ggc gac cgc gca ttg gcc gag 499 Cys Met Val Ala Leu Thr Leu Ala Asp Gly Asp Arg Ala Leu Ala Glu 120 125 130 aac ctg gtc gat gag atc atg tct ggc cgt ttc caa cca gca acc cca 547 Asn Leu Val Asp Glu Ile Met Ser Gly Arg Phe Gln Pro Ala Thr Pro 135 140 145 acc ttc ctg aac tcc ggc aag gca cag cgc ggc gag cca gta tcc tgc 595 Thr Phe Leu Asn Ser Gly Lys Ala Gln Arg Gly Glu Pro Val Ser Cys 150 155 160 165 ttc ctc ctg cgt atc gaa gac aac atg gag tcc atc gga cgt tcc atc 643 Phe Leu Leu Arg Ile Glu Asp Asn Met Glu Ser Ile Gly Arg Ser Ile 170 175 180 aac tct gct ctt cag ctg tcc aag cgt ggc ggt ggc gta gcg ttg ctg 691 Asn Ser Ala Leu Gln Leu Ser Lys Arg Gly Gly Gly Val Ala Leu Leu 185 190 195 ctg tcc aac ctt cgt gaa gcc ggt gca ccg att aag aag att gaa atc 739 Leu Ser Asn Leu Arg Glu Ala Gly Ala Pro Ile Lys Lys Ile Glu Ile 200 205 210 cag tct tcc ggt gtt atc cca gtg atg aaa ctt ctg gaa gat gct ttc 787 Gln Ser Ser Gly Val Ile Pro Val Met Lys Leu Leu Glu Asp Ala Phe 215 220 225 tcc 790 Ser 230 <210> 1068 <211> 230 <212> PRT <213> Corynebacterium glutamicum <400> 1068 Met Asp Phe His Ala Leu Asn Ala Leu Leu Asn Leu Tyr Asp Asp Asn 1 5 10 15 Gly Lys Ile Gln Phe Glu Lys Asp Arg Glu Ala Ala Asn Gln Tyr Phe 20 25 30 Leu Gln His Val Asn Gln Asn Thr Val Phe Phe His Asn Leu Gln Glu 35 40 45 Lys Ile Asp Tyr Leu Val Glu Asn Lys Tyr Tyr Asp Pro Ile Val Leu 50 55 60 Asp Lys Tyr Asp Phe Gln Phe Ile Lys Asp Leu Phe Lys Arg Ala Tyr 65 70 75 80 Gly Phe Lys Phe Arg Phe Gln Ser Phe Leu Gly Ala Tyr Lys Tyr Tyr 85 90 95 Thr Ser Tyr Thr Leu Lys Thr Phe Asp Gly Arg Arg Tyr Leu Glu Arg 100 105 110 Phe Glu Asp Arg Val Cys Met Val Ala Leu Thr Leu Ala Asp Gly Asp 115 120 125 Arg Ala Leu Ala Glu Asn Leu Val Asp Glu Ile Met Ser Gly Arg Phe 130 135 140 Gln Pro Ala Thr Pro Thr Phe Leu Asn Ser Gly Lys Ala Gln Arg Gly 145 150 155 160 Glu Pro Val Ser Cys Phe Leu Leu Arg Ile Glu Asp Asn Met Glu Ser 165 170 175 Ile Gly Arg Ser Ile Asn Ser Ala Leu Gln Leu Ser Lys Arg Gly Gly 180 185 190 Gly Val Ala Leu Leu Leu Ser Asn Leu Arg Glu Ala Gly Ala Pro Ile 195 200 205 Lys Lys Ile Glu Ile Gln Ser Ser Gly Val Ile Pro Val Met Lys Leu 210 215 220 Leu Glu Asp Ala Phe Ser 225 230 <210> 1069 <211> 1364 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1341) <223> FRXA01084 <220> <221> misc_feature <222> 504, 535 <223> n = a, t, c, or g <220> <221> VARIANT <222> 168 <223> Xaa = Ile or Met <220> <221> VARIANT <222> 179 <223> Xaa = Ser, Pro, Thr, or Ala <400> 1069 tcc ttt ctg gat acc aag cgc gag aac gcc gat gag aag atc cgc atc 48 Ser Phe Leu Asp Thr Lys Arg Glu Asn Ala Asp Glu Lys Ile Arg Ile 1 5 10 15 aag acc ctg tcc ctg ggt gtt gtg att ccg gac atc acc ttc gag ctg 96 Lys Thr Leu Ser Leu Gly Val Val Ile Pro Asp Ile Thr Phe Glu Leu 20 25 30 gct aag cgc aac gat gac atg tac ctg ttc tcc cca tac gat gtg gag 144 Ala Lys Arg Asn Asp Asp Met Tyr Leu Phe Ser Pro Tyr Asp Val Glu 35 40 45 cgc att tac ggc aag cct ttc gca gac gtc tca atc acc gag cac tac 192 Arg Ile Tyr Gly Lys Pro Phe Ala Asp Val Ser Ile Thr Glu His Tyr 50 55 60 gac gag atg gtg gat gat gac cgc atc cgc aag acc aag atc aac gcg 240 Asp Glu Met Val Asp Asp Asp Arg Ile Arg Lys Thr Lys Ile Asn Ala 65 70 75 80 cgt cag ttc ttc cag acc ctg gca gaa atc cag ttc gag tcc ggt tac 288 Arg Gln Phe Phe Gln Thr Leu Ala Glu Ile Gln Phe Glu Ser Gly Tyr 85 90 95 cca tac atc atg tat gaa gac acc gtg aat gca tcc aac cca atc gaa 336 Pro Tyr Ile Met Tyr Glu Asp Thr Val Asn Ala Ser Asn Pro Ile Glu 100 105 110 ggt cgc atc acc cac tca aac ctg tgc tct gag atc ctt cag gtg tcc 384 Gly Arg Ile Thr His Ser Asn Leu Cys Ser Glu Ile Leu Gln Val Ser 115 120 125 acc cca tct gaa ttc aac gat gac ctg act tac gca gag gtc ggc gaa 432 Thr Pro Ser Glu Phe Asn Asp Asp Leu Thr Tyr Ala Glu Val Gly Glu 130 135 140 gac att tct tgt aac ttg ggt tcc ctc aac gtt gca atg gct atg gat 480 Asp Ile Ser Cys Asn Leu Gly Ser Leu Asn Val Ala Met Ala Met Asp 145 150 155 160 gca cca aac ttt gag aag acc atn gaa acc gaa atc cgc ggc tta act 528 Ala Pro Asn Phe Glu Lys Thr Xaa Glu Thr Glu Ile Arg Gly Leu Thr 165 170 175 gca gtg nct gag cag acc agc atc gat tcc gtg cct tcc atc cgt aag 576 Ala Val Xaa Glu Gln Thr Ser Ile Asp Ser Val Pro Ser Ile Arg Lys 180 185 190 ggc aac gaa gca gct cac gcc atc ggc ctt ggc cag atg aac ctt cac 624 Gly Asn Glu Ala Ala His Ala Ile Gly Leu Gly Gln Met Asn Leu His 195 200 205 ggc tac ttc ggt cgc gag cac atg cac tac ggc tcc gag gaa gcc ctg 672 Gly Tyr Phe Gly Arg Glu His Met His Tyr Gly Ser Glu Glu Ala Leu 210 215 220 gac ttc acc aac gca tac ttt gct gcc gtg ctg tac cag tgc ctg cgt 720 Asp Phe Thr Asn Ala Tyr Phe Ala Ala Val Leu Tyr Gln Cys Leu Arg 225 230 235 240 gca tcc aac cag atc gct act gag cgt gga gag cgt ttc aag aac ttc 768 Ala Ser Asn Gln Ile Ala Thr Glu Arg Gly Glu Arg Phe Lys Asn Phe 245 250 255 gaa aac tcc aag tat gca acc ggt gag tac ttc gat gat ttc gat gca 816 Glu Asn Ser Lys Tyr Ala Thr Gly Glu Tyr Phe Asp Asp Phe Asp Ala 260 265 270 aac gac ttc gca cca aag tcc gac aag gtc aag gaa ctc ttt gcc aag 864 Asn Asp Phe Ala Pro Lys Ser Asp Lys Val Lys Glu Leu Phe Ala Lys 275 280 285 tcg aac atc cac acc cca acc gtt gag gac tgg gct gcg ctg aag gcc 912 Ser Asn Ile His Thr Pro Thr Val Glu Asp Trp Ala Ala Leu Lys Ala 290 295 300 gac gtg atg gag cac ggt ctg ttc aac cgt aac ctg caa gcg gtt cca 960 Asp Val Met Glu His Gly Leu Phe Asn Arg Asn Leu Gln Ala Val Pro 305 310 315 320 cca acc ggt tcg atc tcc tac atc aac aac tcc acc tcg tcg atc cac 1008 Pro Thr Gly Ser Ile Ser Tyr Ile Asn Asn Ser Thr Ser Ser Ile His 325 330 335 cca atc gca tcc aag att gag atc cgc aag gaa ggc aag atc ggc cgc 1056 Pro Ile Ala Ser Lys Ile Glu Ile Arg Lys Glu Gly Lys Ile Gly Arg 340 345 350 gtt tac tac cca gct cca cac atg gac aat gac aac ctt gag tac ttc 1104 Val Tyr Tyr Pro Ala Pro His Met Asp Asn Asp Asn Leu Glu Tyr Phe 355 360 365 gag gac gcc tac gaa atc ggc tac gag aag atc att gac acc tac gct 1152 Glu Asp Ala Tyr Glu Ile Gly Tyr Glu Lys Ile Ile Asp Thr Tyr Ala 370 375 380 gtg gca acc aag tac gtt gac cag ggc ctg tca ctg acc ttg ttc ttc 1200 Val Ala Thr Lys Tyr Val Asp Gln Gly Leu Ser Leu Thr Leu Phe Phe 385 390 395 400 aag gac act gcc acc acc cgt gac atc aac cgt gcg cag atc tac gca 1248 Lys Asp Thr Ala Thr Thr Arg Asp Ile Asn Arg Ala Gln Ile Tyr Ala 405 410 415 tgg cgc aag ggc atc aag acc ttg tac tac att cgc ctg cgc cag gtt 1296 Trp Arg Lys Gly Ile Lys Thr Leu Tyr Tyr Ile Arg Leu Arg Gln Val 420 425 430 gct ctg gaa ggc act gaa gtt gac ggc tgc gtc agc tgc atg ctg 1341 Ala Leu Glu Gly Thr Glu Val Asp Gly Cys Val Ser Cys Met Leu 435 440 445 taaaagcact taaaaatatc ccc 1364 <210> 1070 <211> 447 <212> PRT <213> Corynebacterium glutamicum <220> <221> VARIANT <222> 168 <223> Xaa = Ile or Met <220> <221> VARIANT <222> 179 <223> Xaa = Ser, Pro, Thr, or Ala <400> 1070 Ser Phe Leu Asp Thr Lys Arg Glu Asn Ala Asp Glu Lys Ile Arg Ile 1 5 10 15 Lys Thr Leu Ser Leu Gly Val Val Ile Pro Asp Ile Thr Phe Glu Leu 20 25 30 Ala Lys Arg Asn Asp Asp Met Tyr Leu Phe Ser Pro Tyr Asp Val Glu 35 40 45 Arg Ile Tyr Gly Lys Pro Phe Ala Asp Val Ser Ile Thr Glu His Tyr 50 55 60 Asp Glu Met Val Asp Asp Asp Arg Ile Arg Lys Thr Lys Ile Asn Ala 65 70 75 80 Arg Gln Phe Phe Gln Thr Leu Ala Glu Ile Gln Phe Glu Ser Gly Tyr 85 90 95 Pro Tyr Ile Met Tyr Glu Asp Thr Val Asn Ala Ser Asn Pro Ile Glu 100 105 110 Gly Arg Ile Thr His Ser Asn Leu Cys Ser Glu Ile Leu Gln Val Ser 115 120 125 Thr Pro Ser Glu Phe Asn Asp Asp Leu Thr Tyr Ala Glu Val Gly Glu 130 135 140 Asp Ile Ser Cys Asn Leu Gly Ser Leu Asn Val Ala Met Ala Met Asp 145 150 155 160 Ala Pro Asn Phe Glu Lys Thr Xaa Glu Thr Glu Ile Arg Gly Leu Thr 165 170 175 Ala Val Xaa Glu Gln Thr Ser Ile Asp Ser Val Pro Ser Ile Arg Lys 180 185 190 Gly Asn Glu Ala Ala His Ala Ile Gly Leu Gly Gln Met Asn Leu His 195 200 205 Gly Tyr Phe Gly Arg Glu His Met His Tyr Gly Ser Glu Glu Ala Leu 210 215 220 Asp Phe Thr Asn Ala Tyr Phe Ala Ala Val Leu Tyr Gln Cys Leu Arg 225 230 235 240 Ala Ser Asn Gln Ile Ala Thr Glu Arg Gly Glu Arg Phe Lys Asn Phe 245 250 255 Glu Asn Ser Lys Tyr Ala Thr Gly Glu Tyr Phe Asp Asp Phe Asp Ala 260 265 270 Asn Asp Phe Ala Pro Lys Ser Asp Lys Val Lys Glu Leu Phe Ala Lys 275 280 285 Ser Asn Ile His Thr Pro Thr Val Glu Asp Trp Ala Ala Leu Lys Ala 290 295 300 Asp Val Met Glu His Gly Leu Phe Asn Arg Asn Leu Gln Ala Val Pro 305 310 315 320 Pro Thr Gly Ser Ile Ser Tyr Ile Asn Asn Ser Thr Ser Ser Ile His 325 330 335 Pro Ile Ala Ser Lys Ile Glu Ile Arg Lys Glu Gly Lys Ile Gly Arg 340 345 350 Val Tyr Tyr Pro Ala Pro His Met Asp Asn Asp Asn Leu Glu Tyr Phe 355 360 365 Glu Asp Ala Tyr Glu Ile Gly Tyr Glu Lys Ile Ile Asp Thr Tyr Ala 370 375 380 Val Ala Thr Lys Tyr Val Asp Gln Gly Leu Ser Leu Thr Leu Phe Phe 385 390 395 400 Lys Asp Thr Ala Thr Thr Arg Asp Ile Asn Arg Ala Gln Ile Tyr Ala 405 410 415 Trp Arg Lys Gly Ile Lys Thr Leu Tyr Tyr Ile Arg Leu Arg Gln Val 420 425 430 Ala Leu Glu Gly Thr Glu Val Asp Gly Cys Val Ser Cys Met Leu 435 440 445 <210> 1071 <211> 1125 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1102) <223> RXN01920 <400> 1071 cttctgaagg gcttcggttg gggtaagctg gcgatctgaa atcgcgctgc attgtggcgt 60 cgaaaagcaa aaaaatttgt agaagggaag agcgcaccta atg gct gct gat tct 115 Met Ala Ala Asp Ser 1 5 gat ctc agt gtt cac gat gct tac tta aag gag cat gtt gca cct gta 163 Asp Leu Ser Val His Asp Ala Tyr Leu Lys Glu His Val Ala Pro Val 10 15 20 aag gcg atc aac tgg aac tcc atc cca gat tcc aaa gat ctt gaa gtc 211 Lys Ala Ile Asn Trp Asn Ser Ile Pro Asp Ser Lys Asp Leu Glu Val 25 30 35 tgg gat cgt ctg acc ggt aac ttc tgg ctc cca gaa aag gtc cca gta 259 Trp Asp Arg Leu Thr Gly Asn Phe Trp Leu Pro Glu Lys Val Pro Val 40 45 50 tcc aac gac atc aag agc tgg gga acc ctc aac gag gtt gaa aaa gcc 307 Ser Asn Asp Ile Lys Ser Trp Gly Thr Leu Asn Glu Val Glu Lys Ala 55 60 65 gca acc atg cgc gtg ttc acc gga ctt acc ctg ctg gac acc att cag 355 Ala Thr Met Arg Val Phe Thr Gly Leu Thr Leu Leu Asp Thr Ile Gln 70 75 80 85 ggc act gtc ggc gca atc tcc ctg ctt cca gac gca gat tca ctg cac 403 Gly Thr Val Gly Ala Ile Ser Leu Leu Pro Asp Ala Asp Ser Leu His 90 95 100 gaa gaa gcg gtg cta acc aac att gcg ttc atg gaa tcc gtg cac gca 451 Glu Glu Ala Val Leu Thr Asn Ile Ala Phe Met Glu Ser Val His Ala 105 110 115 aag agt tac tcc aac atc ttc atg act ctg gcc tcc acc gcg gaa atc 499 Lys Ser Tyr Ser Asn Ile Phe Met Thr Leu Ala Ser Thr Ala Glu Ile 120 125 130 aac gat gcg ttc cgt tgg tct gag gaa aat gaa aac ctg cag cgc aag 547 Asn Asp Ala Phe Arg Trp Ser Glu Glu Asn Glu Asn Leu Gln Arg Lys 135 140 145 gca aag atc atc ctg tct tac tat gag ggc gat gat cca cta aag cgc 595 Ala Lys Ile Ile Leu Ser Tyr Tyr Glu Gly Asp Asp Pro Leu Lys Arg 150 155 160 165 aag atc gcc tcc gtg atc ctg gag tcc ttc ctg ttc tac tcc ggc ttc 643 Lys Ile Ala Ser Val Ile Leu Glu Ser Phe Leu Phe Tyr Ser Gly Phe 170 175 180 tac ctc cca atg tat tgg tcc agc cac tcc aag ctg gcc aac acc gcc 691 Tyr Leu Pro Met Tyr Trp Ser Ser His Ser Lys Leu Ala Asn Thr Ala 185 190 195 gac gtg atc cgc ctg atc atc cgc gat gag gca gtg cac ggc tac tac 739 Asp Val Ile Arg Leu Ile Ile Arg Asp Glu Ala Val His Gly Tyr Tyr 200 205 210 att ggc tac aag tat caa aag gct gtc gcg aag gag act cca gag cgt 787 Ile Gly Tyr Lys Tyr Gln Lys Ala Val Ala Lys Glu Thr Pro Glu Arg 215 220 225 cag gaa gag ctg aag gag tac acc ttc gat ctg ctc tac gat ctt tac 835 Gln Glu Glu Leu Lys Glu Tyr Thr Phe Asp Leu Leu Tyr Asp Leu Tyr 230 235 240 245 gat aac gaa act cag tac tcc gaa gat ctc tac gac gat ctt gga tgg 883 Asp Asn Glu Thr Gln Tyr Ser Glu Asp Leu Tyr Asp Asp Leu Gly Trp 250 255 260 acc gag gat gtt aag cga ttc ctt cgc tac aac gcc aac aag gcc ctc 931 Thr Glu Asp Val Lys Arg Phe Leu Arg Tyr Asn Ala Asn Lys Ala Leu 265 270 275 aac aac ctt ggc tac gaa gga ctc ttc cca gcg gat gaa acc aag gtg 979 Asn Asn Leu Gly Tyr Glu Gly Leu Phe Pro Ala Asp Glu Thr Lys Val 280 285 290 tcc cca aac atc ttg tct gcg ctg tca cca aac gct gat gag aac cac 1027 Ser Pro Asn Ile Leu Ser Ala Leu Ser Pro Asn Ala Asp Glu Asn His 295 300 305 gac ttc ttc tcc ggc tcc ggt tcc tct tac gtt att ggt aag gca gaa 1075 Asp Phe Phe Ser Gly Ser Gly Ser Ser Tyr Val Ile Gly Lys Ala Glu 310 315 320 325 aac acc gag gat gat gac tgg gac ttc taacttttaa aaagctgaag 1122 Asn Thr Glu Asp Asp Asp Trp Asp Phe 330 cgc 1125 <210> 1072 <211> 334 <212> PRT <213> Corynebacterium glutamicum <400> 1072 Met Ala Ala Asp Ser Asp Leu Ser Val His Asp Ala Tyr Leu Lys Glu 1 5 10 15 His Val Ala Pro Val Lys Ala Ile Asn Trp Asn Ser Ile Pro Asp Ser 20 25 30 Lys Asp Leu Glu Val Trp Asp Arg Leu Thr Gly Asn Phe Trp Leu Pro 35 40 45 Glu Lys Val Pro Val Ser Asn Asp Ile Lys Ser Trp Gly Thr Leu Asn 50 55 60 Glu Val Glu Lys Ala Ala Thr Met Arg Val Phe Thr Gly Leu Thr Leu 65 70 75 80 Leu Asp Thr Ile Gln Gly Thr Val Gly Ala Ile Ser Leu Leu Pro Asp 85 90 95 Ala Asp Ser Leu His Glu Glu Ala Val Leu Thr Asn Ile Ala Phe Met 100 105 110 Glu Ser Val His Ala Lys Ser Tyr Ser Asn Ile Phe Met Thr Leu Ala 115 120 125 Ser Thr Ala Glu Ile Asn Asp Ala Phe Arg Trp Ser Glu Glu Asn Glu 130 135 140 Asn Leu Gln Arg Lys Ala Lys Ile Ile Leu Ser Tyr Tyr Glu Gly Asp 145 150 155 160 Asp Pro Leu Lys Arg Lys Ile Ala Ser Val Ile Leu Glu Ser Phe Leu 165 170 175 Phe Tyr Ser Gly Phe Tyr Leu Pro Met Tyr Trp Ser Ser His Ser Lys 180 185 190 Leu Ala Asn Thr Ala Asp Val Ile Arg Leu Ile Ile Arg Asp Glu Ala 195 200 205 Val His Gly Tyr Tyr Ile Gly Tyr Lys Tyr Gln Lys Ala Val Ala Lys 210 215 220 Glu Thr Pro Glu Arg Gln Glu Glu Leu Lys Glu Tyr Thr Phe Asp Leu 225 230 235 240 Leu Tyr Asp Leu Tyr Asp Asn Glu Thr Gln Tyr Ser Glu Asp Leu Tyr 245 250 255 Asp Asp Leu Gly Trp Thr Glu Asp Val Lys Arg Phe Leu Arg Tyr Asn 260 265 270 Ala Asn Lys Ala Leu Asn Asn Leu Gly Tyr Glu Gly Leu Phe Pro Ala 275 280 285 Asp Glu Thr Lys Val Ser Pro Asn Ile Leu Ser Ala Leu Ser Pro Asn 290 295 300 Ala Asp Glu Asn His Asp Phe Phe Ser Gly Ser Gly Ser Ser Tyr Val 305 310 315 320 Ile Gly Lys Ala Glu Asn Thr Glu Asp Asp Asp Trp Asp Phe 325 330 <210> 1073 <211> 437 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(414) <223> FRXA01920 <400> 1073 gcc gac gtg atc cgc ctg atc atc cgc gat gag gca gtg cac ggc tac 48 Ala Asp Val Ile Arg Leu Ile Ile Arg Asp Glu Ala Val His Gly Tyr 1 5 10 15 tac att ggc tac aag tat caa aag gct gtc gcg aag gag act cca gag 96 Tyr Ile Gly Tyr Lys Tyr Gln Lys Ala Val Ala Lys Glu Thr Pro Glu 20 25 30 cgt cag gaa gag ctg aag gag tac acc ttc gat ctg ctc tac gat ctt 144 Arg Gln Glu Glu Leu Lys Glu Tyr Thr Phe Asp Leu Leu Tyr Asp Leu 35 40 45 tac gat aac gaa act cag tac tcc gaa gat ctc tac gac gat ctt gga 192 Tyr Asp Asn Glu Thr Gln Tyr Ser Glu Asp Leu Tyr Asp Asp Leu Gly 50 55 60 tgg acc gag gat gtt aag cga ttc ctt cgc tac aac gcc aac aag gcc 240 Trp Thr Glu Asp Val Lys Arg Phe Leu Arg Tyr Asn Ala Asn Lys Ala 65 70 75 80 ctc aac aac ctt ggc tac gaa gga ctc ttc cca gcg gat gaa acc aag 288 Leu Asn Asn Leu Gly Tyr Glu Gly Leu Phe Pro Ala Asp Glu Thr Lys 85 90 95 gtg tcc cca aac atc ttg tct gcg ctg tca cca aac gct gat gag aac 336 Val Ser Pro Asn Ile Leu Ser Ala Leu Ser Pro Asn Ala Asp Glu Asn 100 105 110 cac gac ttc ttc tcc ggc tcc ggt tcc tct tac gtt att ggt aag gca 384 His Asp Phe Phe Ser Gly Ser Gly Ser Ser Tyr Val Ile Gly Lys Ala 115 120 125 gaa aac acc gag gat gat gac tgg gac ttc taacttttaa aaagctgaag 434 Glu Asn Thr Glu Asp Asp Asp Trp Asp Phe 130 135 cgc 437 <210> 1074 <211> 138 <212> PRT <213> Corynebacterium glutamicum <400> 1074 Ala Asp Val Ile Arg Leu Ile Ile Arg Asp Glu Ala Val His Gly Tyr 1 5 10 15 Tyr Ile Gly Tyr Lys Tyr Gln Lys Ala Val Ala Lys Glu Thr Pro Glu 20 25 30 Arg Gln Glu Glu Leu Lys Glu Tyr Thr Phe Asp Leu Leu Tyr Asp Leu 35 40 45 Tyr Asp Asn Glu Thr Gln Tyr Ser Glu Asp Leu Tyr Asp Asp Leu Gly 50 55 60 Trp Thr Glu Asp Val Lys Arg Phe Leu Arg Tyr Asn Ala Asn Lys Ala 65 70 75 80 Leu Asn Asn Leu Gly Tyr Glu Gly Leu Phe Pro Ala Asp Glu Thr Lys 85 90 95 Val Ser Pro Asn Ile Leu Ser Ala Leu Ser Pro Asn Ala Asp Glu Asn 100 105 110 His Asp Phe Phe Ser Gly Ser Gly Ser Ser Tyr Val Ile Gly Lys Ala 115 120 125 Glu Asn Thr Glu Asp Asp Asp Trp Asp Phe 130 135 <210> 1075 <211> 567 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(544) <223> RXA01080 <400> 1075 ttcagttctt cccttcaacg cccttgaagg gggaaactga taccagcaag cacactaggc 60 ttgcgcacaa acggtattta gaagggaagt gagttcgagg atg cta atc gtg tat 115 Met Leu Ile Val Tyr 1 5 ttt tcc tcg gcc acc gac aac acg cat cgt ttt gta caa aag ctc gat 163 Phe Ser Ser Ala Thr Asp Asn Thr His Arg Phe Val Gln Lys Leu Asp 10 15 20 tta ccc aac gtg cgc atc ccc ctc act agg gtg gaa gaa ccg ctg aaa 211 Leu Pro Asn Val Arg Ile Pro Leu Thr Arg Val Glu Glu Pro Leu Lys 25 30 35 atc aac gag ccc tac gtg cta atc acc ccg acc tat ggt ggt gga gtc 259 Ile Asn Glu Pro Tyr Val Leu Ile Thr Pro Thr Tyr Gly Gly Gly Val 40 45 50 tcc atg act gga gaa aac tcc cgc ccg gtc cca cca caa gtc atc agg 307 Ser Met Thr Gly Glu Asn Ser Arg Pro Val Pro Pro Gln Val Ile Arg 55 60 65 ttt tta aat gat gaa cac aac cgc agc ttc atc agg gca gtt gtt gca 355 Phe Leu Asn Asp Glu His Asn Arg Ser Phe Ile Arg Ala Val Val Ala 70 75 80 85 ggt gga aac tca aac ttc ggc tcc gat ttt ggg ttg gca ggc gag atc 403 Gly Gly Asn Ser Asn Phe Gly Ser Asp Phe Gly Leu Ala Gly Glu Ile 90 95 100 att tcc aag aaa tgt aaa gtg ccc tat gtc tac cgt ttc gag ctc atg 451 Ile Ser Lys Lys Cys Lys Val Pro Tyr Val Tyr Arg Phe Glu Leu Met 105 110 115 ggc aat gag gaa gat gta agt atc ctt cgt gga ggt ctt act caa aac 499 Gly Asn Glu Glu Asp Val Ser Ile Leu Arg Gly Gly Leu Thr Gln Asn 120 125 130 gcc caa gct ttg ggg ctg gaa cca caa gaa cca gtt acc tcg cga 544 Ala Gln Ala Leu Gly Leu Glu Pro Gln Glu Pro Val Thr Ser Arg 135 140 145 taaaccttaa aacttaatca atc 567 <210> 1076 <211> 148 <212> PRT <213> Corynebacterium glutamicum <400> 1076 Met Leu Ile Val Tyr Phe Ser Ser Ala Thr Asp Asn Thr His Arg Phe 1 5 10 15 Val Gln Lys Leu Asp Leu Pro Asn Val Arg Ile Pro Leu Thr Arg Val 20 25 30 Glu Glu Pro Leu Lys Ile Asn Glu Pro Tyr Val Leu Ile Thr Pro Thr 35 40 45 Tyr Gly Gly Gly Val Ser Met Thr Gly Glu Asn Ser Arg Pro Val Pro 50 55 60 Pro Gln Val Ile Arg Phe Leu Asn Asp Glu His Asn Arg Ser Phe Ile 65 70 75 80 Arg Ala Val Val Ala Gly Gly Asn Ser Asn Phe Gly Ser Asp Phe Gly 85 90 95 Leu Ala Gly Glu Ile Ile Ser Lys Lys Cys Lys Val Pro Tyr Val Tyr 100 105 110 Arg Phe Glu Leu Met Gly Asn Glu Glu Asp Val Ser Ile Leu Arg Gly 115 120 125 Gly Leu Thr Gln Asn Ala Gln Ala Leu Gly Leu Glu Pro Gln Glu Pro 130 135 140 Val Thr Ser Arg 145 <210> 1077 <211> 650 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(627) <223> RXA00867 <400> 1077 ttc ggc gac atg gac ttc aag gtt gcc ggc acc gca gac ttc atc acc 48 Phe Gly Asp Met Asp Phe Lys Val Ala Gly Thr Ala Asp Phe Ile Thr 1 5 10 15 gca ctt cag ctg gac acc aag ctg gac ggc att cct tcc aag gtg ctc 96 Ala Leu Gln Leu Asp Thr Lys Leu Asp Gly Ile Pro Ser Lys Val Leu 20 25 30 tcc gat gcg ctt gag cag gca cgc gat gcc cga ctg acc atc ctg aac 144 Ser Asp Ala Leu Glu Gln Ala Arg Asp Ala Arg Leu Thr Ile Leu Asn 35 40 45 acc atg gct gat gtc atc aac gga cct gat gag atg agc aag ttc gct 192 Thr Met Ala Asp Val Ile Asn Gly Pro Asp Glu Met Ser Lys Phe Ala 50 55 60 cct cgc atc acc acc gtg aag atc cca gtg gca aag atc ggt gag ctg 240 Pro Arg Ile Thr Thr Val Lys Ile Pro Val Ala Lys Ile Gly Glu Leu 65 70 75 80 atc gga cca aag ggt aag aac atc aac gct ctt acc gaa gag acc ggc 288 Ile Gly Pro Lys Gly Lys Asn Ile Asn Ala Leu Thr Glu Glu Thr Gly 85 90 95 gca aac atc tcc atc gaa gat gac ggc acc gtg ttc atc tct gca gct 336 Ala Asn Ile Ser Ile Glu Asp Asp Gly Thr Val Phe Ile Ser Ala Ala 100 105 110 gac ggc gca tct gct gaa gcg gcg atc gaa aag atc aac gct ctg gcg 384 Asp Gly Ala Ser Ala Glu Ala Ala Ile Glu Lys Ile Asn Ala Leu Ala 115 120 125 aac cca cag ctg cca aag gtt ggc gag cgc ttc ctc gga acc gtc gtc 432 Asn Pro Gln Leu Pro Lys Val Gly Glu Arg Phe Leu Gly Thr Val Val 130 135 140 aag acc acc gca ttc gga gca ttc gtt tcc ttg ctc cca ggc cgc gac 480 Lys Thr Thr Ala Phe Gly Ala Phe Val Ser Leu Leu Pro Gly Arg Asp 145 150 155 160 ggc ctt gtt cac atc tcc aag ctg ggt aac ggc aag cga gta gaa aag 528 Gly Leu Val His Ile Ser Lys Leu Gly Asn Gly Lys Arg Val Glu Lys 165 170 175 gtc gac gat gtg gtg aag gtt ggc gag aag att cag gtc gaa atc gct 576 Val Asp Asp Val Val Lys Val Gly Glu Lys Ile Gln Val Glu Ile Ala 180 185 190 gac atc gac aac cgc ggc aag atc tcc ttg gtc cca gtt gtt gaa gag 624 Asp Ile Asp Asn Arg Gly Lys Ile Ser Leu Val Pro Val Val Glu Glu 195 200 205 gac taattagttc tggctagatc ggg 650 Asp <210> 1078 <211> 209 <212> PRT <213> Corynebacterium glutamicum <400> 1078 Phe Gly Asp Met Asp Phe Lys Val Ala Gly Thr Ala Asp Phe Ile Thr 1 5 10 15 Ala Leu Gln Leu Asp Thr Lys Leu Asp Gly Ile Pro Ser Lys Val Leu 20 25 30 Ser Asp Ala Leu Glu Gln Ala Arg Asp Ala Arg Leu Thr Ile Leu Asn 35 40 45 Thr Met Ala Asp Val Ile Asn Gly Pro Asp Glu Met Ser Lys Phe Ala 50 55 60 Pro Arg Ile Thr Thr Val Lys Ile Pro Val Ala Lys Ile Gly Glu Leu 65 70 75 80 Ile Gly Pro Lys Gly Lys Asn Ile Asn Ala Leu Thr Glu Glu Thr Gly 85 90 95 Ala Asn Ile Ser Ile Glu Asp Asp Gly Thr Val Phe Ile Ser Ala Ala 100 105 110 Asp Gly Ala Ser Ala Glu Ala Ala Ile Glu Lys Ile Asn Ala Leu Ala 115 120 125 Asn Pro Gln Leu Pro Lys Val Gly Glu Arg Phe Leu Gly Thr Val Val 130 135 140 Lys Thr Thr Ala Phe Gly Ala Phe Val Ser Leu Leu Pro Gly Arg Asp 145 150 155 160 Gly Leu Val His Ile Ser Lys Leu Gly Asn Gly Lys Arg Val Glu Lys 165 170 175 Val Asp Asp Val Val Lys Val Gly Glu Lys Ile Gln Val Glu Ile Ala 180 185 190 Asp Ile Asp Asn Arg Gly Lys Ile Ser Leu Val Pro Val Val Glu Glu 195 200 205 Asp <210> 1079 <211> 630 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(630) <223> RXA01416 <400> 1079 gct ggc gct tcc gaa aac gtt gtc aac cgc gtc aag gac ggt gca cca 48 Ala Gly Ala Ser Glu Asn Val Val Asn Arg Val Lys Asp Gly Ala Pro 1 5 10 15 gca cca acc gaa aag atc gtc tcc gac ggc ctt gaa gca gct aag cca 96 Ala Pro Thr Glu Lys Ile Val Ser Asp Gly Leu Glu Ala Ala Lys Pro 20 25 30 ttc atc gac atc ctg tgc cgc gca cag gaa ggt ctg gca cag cgc gtt 144 Phe Ile Asp Ile Leu Cys Arg Ala Gln Glu Gly Leu Ala Gln Arg Val 35 40 45 gga aac gca gcc aag gaa ttc cca ctg ttc cct cca tac acc gac gag 192 Gly Asn Ala Ala Lys Glu Phe Pro Leu Phe Pro Pro Tyr Thr Asp Glu 50 55 60 gtg tac tcc gca gtg gag cgc aag gta tcc aag aag cta gct tct ttg 240 Val Tyr Ser Ala Val Glu Arg Lys Val Ser Lys Lys Leu Ala Ser Leu 65 70 75 80 ctg acc ctg aag gca aag caa gag cgc gac gac gct acc aac gcc tac 288 Leu Thr Leu Lys Ala Lys Gln Glu Arg Asp Asp Ala Thr Asn Ala Tyr 85 90 95 atg gaa gaa atc gaa gcc gaa ctg ctt cca aag ttc gag gct tcc tac 336 Met Glu Glu Ile Glu Ala Glu Leu Leu Pro Lys Phe Glu Ala Ser Tyr 100 105 110 agc tca gca gct gaa gcg tcc aag gaa atc cgt gca gga tac aac gct 384 Ser Ser Ala Ala Glu Ala Ser Lys Glu Ile Arg Ala Gly Tyr Asn Ala 115 120 125 gtc atg aag gcc atc gtg cgc cgc atg atc ctc acc gat cac ttc cgc 432 Val Met Lys Ala Ile Val Arg Arg Met Ile Leu Thr Asp His Phe Arg 130 135 140 atc gac ggc cgc gga gtc acc gac atc cgt gac ctg gca gta gaa gtt 480 Ile Asp Gly Arg Gly Val Thr Asp Ile Arg Asp Leu Ala Val Glu Val 145 150 155 160 gag ctc atc cca cgt gcg cac ggt tcc tcc ctc ttc gag cgt ggc gag 528 Glu Leu Ile Pro Arg Ala His Gly Ser Ser Leu Phe Glu Arg Gly Glu 165 170 175 acc cag atc ctt ggt gtc acc acc ctg gac atg ctc aag atg gaa cag 576 Thr Gln Ile Leu Gly Val Thr Thr Leu Asp Met Leu Lys Met Glu Gln 180 185 190 caa atc gac tcc ctg gca cca ggc gat gcg aag cgc tac atg cac cac 624 Gln Ile Asp Ser Leu Ala Pro Gly Asp Ala Lys Arg Tyr Met His His 195 200 205 tac aac 630 Tyr Asn 210 <210> 1080 <211> 210 <212> PRT <213> Corynebacterium glutamicum <400> 1080 Ala Gly Ala Ser Glu Asn Val Val Asn Arg Val Lys Asp Gly Ala Pro 1 5 10 15 Ala Pro Thr Glu Lys Ile Val Ser Asp Gly Leu Glu Ala Ala Lys Pro 20 25 30 Phe Ile Asp Ile Leu Cys Arg Ala Gln Glu Gly Leu Ala Gln Arg Val 35 40 45 Gly Asn Ala Ala Lys Glu Phe Pro Leu Phe Pro Pro Tyr Thr Asp Glu 50 55 60 Val Tyr Ser Ala Val Glu Arg Lys Val Ser Lys Lys Leu Ala Ser Leu 65 70 75 80 Leu Thr Leu Lys Ala Lys Gln Glu Arg Asp Asp Ala Thr Asn Ala Tyr 85 90 95 Met Glu Glu Ile Glu Ala Glu Leu Leu Pro Lys Phe Glu Ala Ser Tyr 100 105 110 Ser Ser Ala Ala Glu Ala Ser Lys Glu Ile Arg Ala Gly Tyr Asn Ala 115 120 125 Val Met Lys Ala Ile Val Arg Arg Met Ile Leu Thr Asp His Phe Arg 130 135 140 Ile Asp Gly Arg Gly Val Thr Asp Ile Arg Asp Leu Ala Val Glu Val 145 150 155 160 Glu Leu Ile Pro Arg Ala His Gly Ser Ser Leu Phe Glu Arg Gly Glu 165 170 175 Thr Gln Ile Leu Gly Val Thr Thr Leu Asp Met Leu Lys Met Glu Gln 180 185 190 Gln Ile Asp Ser Leu Ala Pro Gly Asp Ala Lys Arg Tyr Met His His 195 200 205 Tyr Asn 210 <210> 1081 <211> 757 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(757) <223> RXA01486 <400> 1081 agagaactgg taaggttttt accgttctag accgcagaaa tcttcgcggc gacaccgatg 60 atcgccgagc agaactaaac atgaggagac ctactcgcat atg agc gat gta aag 115 Met Ser Asp Val Lys 1 5 gac ttc gaa gac acc gaa ttt ggc ctg atc gag gcc gtc gca acc atc 163 Asp Phe Glu Asp Thr Glu Phe Gly Leu Ile Glu Ala Val Ala Thr Ile 10 15 20 gac aac ggt gac ttc gga acc cgc acc atc cgt ttt gaa acc ggc caa 211 Asp Asn Gly Asp Phe Gly Thr Arg Thr Ile Arg Phe Glu Thr Gly Gln 25 30 35 ctt gcc cgc cag gca gat ggt gca gtg acc acc tac ctc gac gat gac 259 Leu Ala Arg Gln Ala Asp Gly Ala Val Thr Thr Tyr Leu Asp Asp Asp 40 45 50 acg atg ctg ctg gca acc acc acc gca tcc aac cag cca cgc gag ggc 307 Thr Met Leu Leu Ala Thr Thr Thr Ala Ser Asn Gln Pro Arg Glu Gly 55 60 65 ttt gac ttc ttc cca ctg acc gtg gac gtt gaa gag cgt atg tac gca 355 Phe Asp Phe Phe Pro Leu Thr Val Asp Val Glu Glu Arg Met Tyr Ala 70 75 80 85 gct ggt cgc atc cct ggc tct ttc ttc cgt cgg gag ggt cgc cca tcc 403 Ala Gly Arg Ile Pro Gly Ser Phe Phe Arg Arg Glu Gly Arg Pro Ser 90 95 100 acc gaa gct atc ctg gct tgc cgt ctc atc gac cgc cca ctg cgc cca 451 Thr Glu Ala Ile Leu Ala Cys Arg Leu Ile Asp Arg Pro Leu Arg Pro 105 110 115 acc ttt gtt aag ggc ctg cgc aat gag gtt cag atc gtt gtc acc gtc 499 Thr Phe Val Lys Gly Leu Arg Asn Glu Val Gln Ile Val Val Thr Val 120 125 130 atg tcc atg aac cct gag gat tac tac gat gtc gta gca atc aac gga 547 Met Ser Met Asn Pro Glu Asp Tyr Tyr Asp Val Val Ala Ile Asn Gly 135 140 145 gct tcc gca gca acc cgc atc tcc gga ctt cct gtc tcc ggc gct gtc 595 Ala Ser Ala Ala Thr Arg Ile Ser Gly Leu Pro Val Ser Gly Ala Val 150 155 160 165 ggt ggc gtt cgc atg gca ctg gtt ggt gat gaa aag cac cca gaa ggc 643 Gly Gly Val Arg Met Ala Leu Val Gly Asp Glu Lys His Pro Glu Gly 170 175 180 caa tgg gtt gca ttc cca acc cac gct caa cat gag cag tcc gta ttt 691 Gln Trp Val Ala Phe Pro Thr His Ala Gln His Glu Gln Ser Val Phe 185 190 195 gaa atc gtt gtg gct ggt cgc ctc gtc gag cgc aag cgc ggc aac aag 739 Glu Ile Val Val Ala Gly Arg Leu Val Glu Arg Lys Arg Gly Asn Lys 200 205 210 acc ttc tcc gac gtc gca 757 Thr Phe Ser Asp Val Ala 215 <210> 1082 <211> 219 <212> PRT <213> Corynebacterium glutamicum <400> 1082 Met Ser Asp Val Lys Asp Phe Glu Asp Thr Glu Phe Gly Leu Ile Glu 1 5 10 15 Ala Val Ala Thr Ile Asp Asn Gly Asp Phe Gly Thr Arg Thr Ile Arg 20 25 30 Phe Glu Thr Gly Gln Leu Ala Arg Gln Ala Asp Gly Ala Val Thr Thr 35 40 45 Tyr Leu Asp Asp Asp Thr Met Leu Leu Ala Thr Thr Thr Ala Ser Asn 50 55 60 Gln Pro Arg Glu Gly Phe Asp Phe Phe Pro Leu Thr Val Asp Val Glu 65 70 75 80 Glu Arg Met Tyr Ala Ala Gly Arg Ile Pro Gly Ser Phe Phe Arg Arg 85 90 95 Glu Gly Arg Pro Ser Thr Glu Ala Ile Leu Ala Cys Arg Leu Ile Asp 100 105 110 Arg Pro Leu Arg Pro Thr Phe Val Lys Gly Leu Arg Asn Glu Val Gln 115 120 125 Ile Val Val Thr Val Met Ser Met Asn Pro Glu Asp Tyr Tyr Asp Val 130 135 140 Val Ala Ile Asn Gly Ala Ser Ala Ala Thr Arg Ile Ser Gly Leu Pro 145 150 155 160 Val Ser Gly Ala Val Gly Gly Val Arg Met Ala Leu Val Gly Asp Glu 165 170 175 Lys His Pro Glu Gly Gln Trp Val Ala Phe Pro Thr His Ala Gln His 180 185 190 Glu Gln Ser Val Phe Glu Ile Val Val Ala Gly Arg Leu Val Glu Arg 195 200 205 Lys Arg Gly Asn Lys Thr Phe Ser Asp Val Ala 210 215 <210> 1083 <211> 651 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(628) <223> RXA01678 <400> 1083 tattgtccag gcgcaggaaa atatctcata gttcaacatc gcaaatatca ccgacttcca 60 cggctatatc tctgcaactg cagctcaccc cggtgcagca atg ctg aaa tgt gca 115 Met Leu Lys Cys Ala 1 5 gtc gat gaa gcc gct ggc gga cgc gcc caa gct ttc gta tcc tca ggc 163 Val Asp Glu Ala Ala Gly Gly Arg Ala Gln Ala Phe Val Ser Ser Gly 10 15 20 gat aac att ggt ggc agc ccg ttc caa tcc tcc att ctt ggt gat gaa 211 Asp Asn Ile Gly Gly Ser Pro Phe Gln Ser Ser Ile Leu Gly Asp Glu 25 30 35 ccc acc ttg gaa gca ctc aac caa atg ggt ctt gat tac tca gca gtg 259 Pro Thr Leu Glu Ala Leu Asn Gln Met Gly Leu Asp Tyr Ser Ala Val 40 45 50 ggc aac cac gaa ttt gat aaa ggc tac gca gac tta agc agt cga gtc 307 Gly Asn His Glu Phe Asp Lys Gly Tyr Ala Asp Leu Ser Ser Arg Val 55 60 65 gct gac ctt gct gat ttt gat tat ctc ggc gca aac gtt gag ggc gaa 355 Ala Asp Leu Ala Asp Phe Asp Tyr Leu Gly Ala Asn Val Glu Gly Glu 70 75 80 85 aac cca gat ctt gca cca tat gga att tct cac ctt gat ggt gtg aag 403 Asn Pro Asp Leu Ala Pro Tyr Gly Ile Ser His Leu Asp Gly Val Lys 90 95 100 gtt gct ttc gta ggc acc gta tcc caa gaa act ccg atg ttg gtc aat 451 Val Ala Phe Val Gly Thr Val Ser Gln Glu Thr Pro Met Leu Val Asn 105 110 115 tct gaa ggc att gag gga atc acg ttt act gac cca ctt gaa gca acc 499 Ser Glu Gly Ile Glu Gly Ile Thr Phe Thr Asp Pro Leu Glu Ala Thr 120 125 130 aac cgt gta gct gat gaa ctc gtg gga agt ggc gca gca gat gtt gtc 547 Asn Arg Val Ala Asp Glu Leu Val Gly Ser Gly Ala Ala Asp Val Val 135 140 145 gtt gcg ctt tac cac gaa ggc att acc ggc acc gaa gca tgg tca gaa 595 Val Ala Leu Tyr His Glu Gly Ile Thr Gly Thr Glu Ala Trp Ser Glu 150 155 160 165 aat atc gac gtt gtt ttc gca ggt cac acc cac taagttcgtg atctaggaac 648 Asn Ile Asp Val Val Phe Ala Gly His Thr His 170 175 cga 651 <210> 1084 <211> 176 <212> PRT <213> Corynebacterium glutamicum <400> 1084 Met Leu Lys Cys Ala Val Asp Glu Ala Ala Gly Gly Arg Ala Gln Ala 1 5 10 15 Phe Val Ser Ser Gly Asp Asn Ile Gly Gly Ser Pro Phe Gln Ser Ser 20 25 30 Ile Leu Gly Asp Glu Pro Thr Leu Glu Ala Leu Asn Gln Met Gly Leu 35 40 45 Asp Tyr Ser Ala Val Gly Asn His Glu Phe Asp Lys Gly Tyr Ala Asp 50 55 60 Leu Ser Ser Arg Val Ala Asp Leu Ala Asp Phe Asp Tyr Leu Gly Ala 65 70 75 80 Asn Val Glu Gly Glu Asn Pro Asp Leu Ala Pro Tyr Gly Ile Ser His 85 90 95 Leu Asp Gly Val Lys Val Ala Phe Val Gly Thr Val Ser Gln Glu Thr 100 105 110 Pro Met Leu Val Asn Ser Glu Gly Ile Glu Gly Ile Thr Phe Thr Asp 115 120 125 Pro Leu Glu Ala Thr Asn Arg Val Ala Asp Glu Leu Val Gly Ser Gly 130 135 140 Ala Ala Asp Val Val Val Ala Leu Tyr His Glu Gly Ile Thr Gly Thr 145 150 155 160 Glu Ala Trp Ser Glu Asn Ile Asp Val Val Phe Ala Gly His Thr His 165 170 175 <210> 1085 <211> 1359 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1336) <223> RXA01679 <400> 1085 cattaccggc accgaagcat ggtcagaaaa tatcgacgtt gttttcgcag gtcacaccca 60 ctaagttcgt gatctaggaa ccgacaacgg tccactaatc atg cag tct gga aac 115 Met Gln Ser Gly Asn 1 5 tac ggg cac gca ctt gcc gat gta gat ttc agc ttc aac cac gac acc 163 Tyr Gly His Ala Leu Ala Asp Val Asp Phe Ser Phe Asn His Asp Thr 10 15 20 ggt gag ctc acc gta gat gat gcc cgc atg ctc gga gtc gac gat atc 211 Gly Glu Leu Thr Val Asp Asp Ala Arg Met Leu Gly Val Asp Asp Ile 25 30 35 aac gcg tgt gaa aac cca gat gac acc att gca gat att gtt gct cag 259 Asn Ala Cys Glu Asn Pro Asp Asp Thr Ile Ala Asp Ile Val Ala Gln 40 45 50 gcg gaa ctt gat gct ggt gaa gcc ggc aaa gaa gta gta gcg acc atc 307 Ala Glu Leu Asp Ala Gly Glu Ala Gly Lys Glu Val Val Ala Thr Ile 55 60 65 gat ggc gat ttt ctc cgc gcc agc gac gaa gga gca gaa tct ggc tcc 355 Asp Gly Asp Phe Leu Arg Ala Ser Asp Glu Gly Ala Glu Ser Gly Ser 70 75 80 85 aac tac ggc gct gaa tcc cag ctc gtc aac atg att gcc agt gct gtg 403 Asn Tyr Gly Ala Glu Ser Gln Leu Val Asn Met Ile Ala Ser Ala Val 90 95 100 cgt tgg tcc atg tcc acc aat acc gcc acc acc gca gac att ggg ctt 451 Arg Trp Ser Met Ser Thr Asn Thr Ala Thr Thr Ala Asp Ile Gly Leu 105 110 115 atg aac gcc gga gga ctc cac act gac cta ttc agc ggc gat gtt acc 499 Met Asn Ala Gly Gly Leu His Thr Asp Leu Phe Ser Gly Asp Val Thr 120 125 130 tac gcc gaa gct ttt gaa atc cag cct ttc tcc ggt gaa gat tca ttt 547 Tyr Ala Glu Ala Phe Glu Ile Gln Pro Phe Ser Gly Glu Asp Ser Phe 135 140 145 gtc acc ctc aag gga tca gtc ttc aaa gat gcc ctt gac cag cag tgg 595 Val Thr Leu Lys Gly Ser Val Phe Lys Asp Ala Leu Asp Gln Gln Trp 150 155 160 165 gaa gaa ggt tct gca cga cca gtg gca gca ctt ggc gta tcc gac aac 643 Glu Glu Gly Ser Ala Arg Pro Val Ala Ala Leu Gly Val Ser Asp Asn 170 175 180 gtt tcc tac acc tac gac atc aac cgt cca atc ggt gac cgc gtc act 691 Val Ser Tyr Thr Tyr Asp Ile Asn Arg Pro Ile Gly Asp Arg Val Thr 185 190 195 tcc gtg acc att gat gat acc cca ctt gat ccg gaa cgc gac tac gtt 739 Ser Val Thr Ile Asp Asp Thr Pro Leu Asp Pro Glu Arg Asp Tyr Val 200 205 210 gtt gca gct tcc ctg tac ctc cag tcc ggc aac gaa ggt atg acc gca 787 Val Ala Ala Ser Leu Tyr Leu Gln Ser Gly Asn Glu Gly Met Thr Ala 215 220 225 ctg acc cgc gga acc gca cct gca caa acc ggc atc gtg gat gta cag 835 Leu Thr Arg Gly Thr Ala Pro Ala Gln Thr Gly Ile Val Asp Val Gln 230 235 240 245 tcc acc atc gga tac ttg tcc aac aac aat gtc acc cca cgt act ggt 883 Ser Thr Ile Gly Tyr Leu Ser Asn Asn Asn Val Thr Pro Arg Thr Gly 250 255 260 caa gcc cag att tcc atc acc cca tcc ggt gag ttc aat gcg ggt gaa 931 Gln Ala Gln Ile Ser Ile Thr Pro Ser Gly Glu Phe Asn Ala Gly Glu 265 270 275 acc atc acc ctt gac atg gca gga ctc cgc tac acc caa ggc gac act 979 Thr Ile Thr Leu Asp Met Ala Gly Leu Arg Tyr Thr Gln Gly Asp Thr 280 285 290 gcc acg gaa gta act gtc agc ctt cga gaa gaa att gtt tca gca cca 1027 Ala Thr Glu Val Thr Val Ser Leu Arg Glu Glu Ile Val Ser Ala Pro 295 300 305 att gat cct cag ctc gga gaa gct ggc ttt ggc gaa gct gga acc gcg 1075 Ile Asp Pro Gln Leu Gly Glu Ala Gly Phe Gly Glu Ala Gly Thr Ala 310 315 320 325 aca gtg agc ttg gac att cct gca acc ctt tca ggt act caa aac ctc 1123 Thr Val Ser Leu Asp Ile Pro Ala Thr Leu Ser Gly Thr Gln Asn Leu 330 335 340 gtt gtc acc acc gat acc ggc acc cgt att tcc atg cca gtt gag att 1171 Val Val Thr Thr Asp Thr Gly Thr Arg Ile Ser Met Pro Val Glu Ile 345 350 355 gtt ggc gca gaa caa cca gca ccg caa cca gca ggt tcc tct gtt tta 1219 Val Gly Ala Glu Gln Pro Ala Pro Gln Pro Ala Gly Ser Ser Val Leu 360 365 370 gga act gga gtg ctc agt gga ctc ctc ggc att gtt gta gga att cta 1267 Gly Thr Gly Val Leu Ser Gly Leu Leu Gly Ile Val Val Gly Ile Leu 375 380 385 gga atg gtc ggt ctg gtg aac tgg att gac cca agc ttc att caa cag 1315 Gly Met Val Gly Leu Val Asn Trp Ile Asp Pro Ser Phe Ile Gln Gln 390 395 400 405 atc cag cag caa atc ttt gct taaatttagt aaaaagcatg cat 1359 Ile Gln Gln Gln Ile Phe Ala 410 <210> 1086 <211> 412 <212> PRT <213> Corynebacterium glutamicum <400> 1086 Met Gln Ser Gly Asn Tyr Gly His Ala Leu Ala Asp Val Asp Phe Ser 1 5 10 15 Phe Asn His Asp Thr Gly Glu Leu Thr Val Asp Asp Ala Arg Met Leu 20 25 30 Gly Val Asp Asp Ile Asn Ala Cys Glu Asn Pro Asp Asp Thr Ile Ala 35 40 45 Asp Ile Val Ala Gln Ala Glu Leu Asp Ala Gly Glu Ala Gly Lys Glu 50 55 60 Val Val Ala Thr Ile Asp Gly Asp Phe Leu Arg Ala Ser Asp Glu Gly 65 70 75 80 Ala Glu Ser Gly Ser Asn Tyr Gly Ala Glu Ser Gln Leu Val Asn Met 85 90 95 Ile Ala Ser Ala Val Arg Trp Ser Met Ser Thr Asn Thr Ala Thr Thr 100 105 110 Ala Asp Ile Gly Leu Met Asn Ala Gly Gly Leu His Thr Asp Leu Phe 115 120 125 Ser Gly Asp Val Thr Tyr Ala Glu Ala Phe Glu Ile Gln Pro Phe Ser 130 135 140 Gly Glu Asp Ser Phe Val Thr Leu Lys Gly Ser Val Phe Lys Asp Ala 145 150 155 160 Leu Asp Gln Gln Trp Glu Glu Gly Ser Ala Arg Pro Val Ala Ala Leu 165 170 175 Gly Val Ser Asp Asn Val Ser Tyr Thr Tyr Asp Ile Asn Arg Pro Ile 180 185 190 Gly Asp Arg Val Thr Ser Val Thr Ile Asp Asp Thr Pro Leu Asp Pro 195 200 205 Glu Arg Asp Tyr Val Val Ala Ala Ser Leu Tyr Leu Gln Ser Gly Asn 210 215 220 Glu Gly Met Thr Ala Leu Thr Arg Gly Thr Ala Pro Ala Gln Thr Gly 225 230 235 240 Ile Val Asp Val Gln Ser Thr Ile Gly Tyr Leu Ser Asn Asn Asn Val 245 250 255 Thr Pro Arg Thr Gly Gln Ala Gln Ile Ser Ile Thr Pro Ser Gly Glu 260 265 270 Phe Asn Ala Gly Glu Thr Ile Thr Leu Asp Met Ala Gly Leu Arg Tyr 275 280 285 Thr Gln Gly Asp Thr Ala Thr Glu Val Thr Val Ser Leu Arg Glu Glu 290 295 300 Ile Val Ser Ala Pro Ile Asp Pro Gln Leu Gly Glu Ala Gly Phe Gly 305 310 315 320 Glu Ala Gly Thr Ala Thr Val Ser Leu Asp Ile Pro Ala Thr Leu Ser 325 330 335 Gly Thr Gln Asn Leu Val Val Thr Thr Asp Thr Gly Thr Arg Ile Ser 340 345 350 Met Pro Val Glu Ile Val Gly Ala Glu Gln Pro Ala Pro Gln Pro Ala 355 360 365 Gly Ser Ser Val Leu Gly Thr Gly Val Leu Ser Gly Leu Leu Gly Ile 370 375 380 Val Val Gly Ile Leu Gly Met Val Gly Leu Val Asn Trp Ile Asp Pro 385 390 395 400 Ser Phe Ile Gln Gln Ile Gln Gln Gln Ile Phe Ala 405 410 <210> 1087 <211> 1071 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1048) <223> RXN01488 <400> 1087 ccagcgctta aggccggtca ccggccatca agcttgtcac atcgggtgcc ttatgatggt 60 gcccgacctt aaaaataaaa acctgaaagg ttaaaaacgc atg agc aaa aaa gcc 115 Met Ser Lys Lys Ala 1 5 atc ctt gat atc gac acc ggc atc gat gat gcc ctc gca ctt gcc tac 163 Ile Leu Asp Ile Asp Thr Gly Ile Asp Asp Ala Leu Ala Leu Ala Tyr 10 15 20 gca ctg ggc tca cct gaa cta gag ctc att ggt gtc acc acc acc tac 211 Ala Leu Gly Ser Pro Glu Leu Glu Leu Ile Gly Val Thr Thr Thr Tyr 25 30 35 ggt aac gtg cta ctc gaa acc ggt gca gtc aat gac ctg gca ctg ctt 259 Gly Asn Val Leu Leu Glu Thr Gly Ala Val Asn Asp Leu Ala Leu Leu 40 45 50 gat ctg ttc ggt gca cca gaa gta cct gtg tac ttg ggt gag cca cac 307 Asp Leu Phe Gly Ala Pro Glu Val Pro Val Tyr Leu Gly Glu Pro His 55 60 65 gca cag acc aag gat ggc ttt gaa gtt ctt gag atc tcc gcg ttc att 355 Ala Gln Thr Lys Asp Gly Phe Glu Val Leu Glu Ile Ser Ala Phe Ile 70 75 80 85 cac gga caa aac ggc atc ggc gaa gtc gag ctg cca gca agc gag tca 403 His Gly Gln Asn Gly Ile Gly Glu Val Glu Leu Pro Ala Ser Glu Ser 90 95 100 aag gca ctc ccc ggc gca gtg gat ttc ctc att gat tcc gtc aac acc 451 Lys Ala Leu Pro Gly Ala Val Asp Phe Leu Ile Asp Ser Val Asn Thr 105 110 115 cac ggc gat gac ctg gtg atc atc gca act ggt ccc atg acc aac ctg 499 His Gly Asp Asp Leu Val Ile Ile Ala Thr Gly Pro Met Thr Asn Leu 120 125 130 tct gcg gca atc gca aag gat cca agc ttt gct tcc aag gct cac gtg 547 Ser Ala Ala Ile Ala Lys Asp Pro Ser Phe Ala Ser Lys Ala His Val 135 140 145 gtc atc atg ggt ggc gcc ttg act gtc cca ggc aac gtc agc aca tgg 595 Val Ile Met Gly Gly Ala Leu Thr Val Pro Gly Asn Val Ser Thr Trp 150 155 160 165 gca gaa gca aac atc aac cag gac cca gat gca gca aac gat ctg ttc 643 Ala Glu Ala Asn Ile Asn Gln Asp Pro Asp Ala Ala Asn Asp Leu Phe 170 175 180 cgt tcc ggt gca gat gtc acc atg atc ggt ctt gat gtc acc ctg cag 691 Arg Ser Gly Ala Asp Val Thr Met Ile Gly Leu Asp Val Thr Leu Gln 185 190 195 acc ctt ctt acc aag aag cac act gcg cag tgg cgc gaa ctg ggc act 739 Thr Leu Leu Thr Lys Lys His Thr Ala Gln Trp Arg Glu Leu Gly Thr 200 205 210 cca gct gct atc gca ctg gcc gac atg act gat tac tac atc aag gca 787 Pro Ala Ala Ile Ala Leu Ala Asp Met Thr Asp Tyr Tyr Ile Lys Ala 215 220 225 tat gag acc acc gca cca cac ctg ggc ggt tgc ggc ctg cac gac cca 835 Tyr Glu Thr Thr Ala Pro His Leu Gly Gly Cys Gly Leu His Asp Pro 230 235 240 245 ctg gca gta ggc gtt gca gtg gac cca agc ctg gtc act ttg ctc ccc 883 Leu Ala Val Gly Val Ala Val Asp Pro Ser Leu Val Thr Leu Leu Pro 250 255 260 atc aac ctc aag gta gac att gag ggc gag acc cgt gga cgc acc att 931 Ile Asn Leu Lys Val Asp Ile Glu Gly Glu Thr Arg Gly Arg Thr Ile 265 270 275 ggc gat gaa gtc cgc ctc aac gat cca gtg cgc acc tcc cgc gca gct 979 Gly Asp Glu Val Arg Leu Asn Asp Pro Val Arg Thr Ser Arg Ala Ala 280 285 290 gtc gcc gta gac gtg gat cgt ttc ctt tct gaa ttc atg acc cgc atc 1027 Val Ala Val Asp Val Asp Arg Phe Leu Ser Glu Phe Met Thr Arg Ile 295 300 305 ggc cga gtc gca gca cag cag taaaagcagc tctggtgaag gtt 1071 Gly Arg Val Ala Ala Gln Gln 310 315 <210> 1088 <211> 316 <212> PRT <213> Corynebacterium glutamicum <400> 1088 Met Ser Lys Lys Ala Ile Leu Asp Ile Asp Thr Gly Ile Asp Asp Ala 1 5 10 15 Leu Ala Leu Ala Tyr Ala Leu Gly Ser Pro Glu Leu Glu Leu Ile Gly 20 25 30 Val Thr Thr Thr Tyr Gly Asn Val Leu Leu Glu Thr Gly Ala Val Asn 35 40 45 Asp Leu Ala Leu Leu Asp Leu Phe Gly Ala Pro Glu Val Pro Val Tyr 50 55 60 Leu Gly Glu Pro His Ala Gln Thr Lys Asp Gly Phe Glu Val Leu Glu 65 70 75 80 Ile Ser Ala Phe Ile His Gly Gln Asn Gly Ile Gly Glu Val Glu Leu 85 90 95 Pro Ala Ser Glu Ser Lys Ala Leu Pro Gly Ala Val Asp Phe Leu Ile 100 105 110 Asp Ser Val Asn Thr His Gly Asp Asp Leu Val Ile Ile Ala Thr Gly 115 120 125 Pro Met Thr Asn Leu Ser Ala Ala Ile Ala Lys Asp Pro Ser Phe Ala 130 135 140 Ser Lys Ala His Val Val Ile Met Gly Gly Ala Leu Thr Val Pro Gly 145 150 155 160 Asn Val Ser Thr Trp Ala Glu Ala Asn Ile Asn Gln Asp Pro Asp Ala 165 170 175 Ala Asn Asp Leu Phe Arg Ser Gly Ala Asp Val Thr Met Ile Gly Leu 180 185 190 Asp Val Thr Leu Gln Thr Leu Leu Thr Lys Lys His Thr Ala Gln Trp 195 200 205 Arg Glu Leu Gly Thr Pro Ala Ala Ile Ala Leu Ala Asp Met Thr Asp 210 215 220 Tyr Tyr Ile Lys Ala Tyr Glu Thr Thr Ala Pro His Leu Gly Gly Cys 225 230 235 240 Gly Leu His Asp Pro Leu Ala Val Gly Val Ala Val Asp Pro Ser Leu 245 250 255 Val Thr Leu Leu Pro Ile Asn Leu Lys Val Asp Ile Glu Gly Glu Thr 260 265 270 Arg Gly Arg Thr Ile Gly Asp Glu Val Arg Leu Asn Asp Pro Val Arg 275 280 285 Thr Ser Arg Ala Ala Val Ala Val Asp Val Asp Arg Phe Leu Ser Glu 290 295 300 Phe Met Thr Arg Ile Gly Arg Val Ala Ala Gln Gln 305 310 315 <210> 1089 <211> 366 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(343) <223> RXC00540 <400> 1089 tctccctatc taagggctgg ctaggtttga ccagtggcaa cagttacact tgtgctcgta 60 aaacattgtc ctccccattt cttgagtaag ggaaaatacc gtg gcc cgt gta gtt 115 Val Ala Arg Val Val 1 5 gtc aat gtc atg cct aag gct gag att ctg gat ccc cag ggg cag gcg 163 Val Asn Val Met Pro Lys Ala Glu Ile Leu Asp Pro Gln Gly Gln Ala 10 15 20 gta cac cgc gcc ctc gga cgt atc gga gtt tct ggc gtt tcc gat gtc 211 Val His Arg Ala Leu Gly Arg Ile Gly Val Ser Gly Val Ser Asp Val 25 30 35 cgt cag gga aag cgc ttc gag ctt gag gta gat gat tcc gtc acc gaa 259 Arg Gln Gly Lys Arg Phe Glu Leu Glu Val Asp Asp Ser Val Thr Glu 40 45 50 gct gac cta aag aaa att gct gaa acc ctc ctc gca aac acc gtc atc 307 Ala Asp Leu Lys Lys Ile Ala Glu Thr Leu Leu Ala Asn Thr Val Ile 55 60 65 gaa gac ttc gat gtg gtg gga gtt gag gtc gcg aag tgagcgccaa 353 Glu Asp Phe Asp Val Val Gly Val Glu Val Ala Lys 70 75 80 aatcggtgtc att 366 <210> 1090 <211> 81 <212> PRT <213> Corynebacterium glutamicum <400> 1090 Val Ala Arg Val Val Val Asn Val Met Pro Lys Ala Glu Ile Leu Asp 1 5 10 15 Pro Gln Gly Gln Ala Val His Arg Ala Leu Gly Arg Ile Gly Val Ser 20 25 30 Gly Val Ser Asp Val Arg Gln Gly Lys Arg Phe Glu Leu Glu Val Asp 35 40 45 Asp Ser Val Thr Glu Ala Asp Leu Lys Lys Ile Ala Glu Thr Leu Leu 50 55 60 Ala Asn Thr Val Ile Glu Asp Phe Asp Val Val Gly Val Glu Val Ala 65 70 75 80 Lys <210> 1091 <211> 498 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(475) <223> RXC00560 <400> 1091 aaggacgact tctggggagc ggtgtggatt ctcacgggga ttctcatgcg gattatcaga 60 catatggaca ctttaacggt tcgtactagg ctgatgcttc atg agg att gat ccg 115 Met Arg Ile Asp Pro 1 5 ctg gaa acc cgg caa gcc gta ttg gcc gtc aaa gac tgg att gaa ggg 163 Leu Glu Thr Arg Gln Ala Val Leu Ala Val Lys Asp Trp Ile Glu Gly 10 15 20 gag gga gac gtc aaa aag cct ggt cgt gcg gca ctt gcc gcc gca act 211 Glu Gly Asp Val Lys Lys Pro Gly Arg Ala Ala Leu Ala Ala Ala Thr 25 30 35 cgc ctg agc gtc cga ctg ctc gcg caa cac gcg ccg gga aac agc gtg 259 Arg Leu Ser Val Arg Leu Leu Ala Gln His Ala Pro Gly Asn Ser Val 40 45 50 gag gtg cgg gta ccc cca ttt gtt gcg gtg caa tgc ata gag ggg cca 307 Glu Val Arg Val Pro Pro Phe Val Ala Val Gln Cys Ile Glu Gly Pro 55 60 65 aaa cat aca cgc ggc aca cca ccc aac gtg gtg gag acc gac gcc aag 355 Lys His Thr Arg Gly Thr Pro Pro Asn Val Val Glu Thr Asp Ala Lys 70 75 80 85 acc tgg tta cgc tta gca cct ggg caa acc aca ttt gat gca gaa ttt 403 Thr Trp Leu Arg Leu Ala Pro Gly Gln Thr Thr Phe Asp Ala Glu Phe 90 95 100 gaa agc gga aaa att agc gca tca ggt acc cga gcc aaa gag att gcg 451 Glu Ser Gly Lys Ile Ser Ala Ser Gly Thr Arg Ala Lys Glu Ile Ala 105 110 115 gac tgg tta cca gtg gtc aaa ctt tagatttcct aatgctcatt agt 498 Asp Trp Leu Pro Val Val Lys Leu 120 125 <210> 1092 <211> 125 <212> PRT <213> Corynebacterium glutamicum <400> 1092 Met Arg Ile Asp Pro Leu Glu Thr Arg Gln Ala Val Leu Ala Val Lys 1 5 10 15 Asp Trp Ile Glu Gly Glu Gly Asp Val Lys Lys Pro Gly Arg Ala Ala 20 25 30 Leu Ala Ala Ala Thr Arg Leu Ser Val Arg Leu Leu Ala Gln His Ala 35 40 45 Pro Gly Asn Ser Val Glu Val Arg Val Pro Pro Phe Val Ala Val Gln 50 55 60 Cys Ile Glu Gly Pro Lys His Thr Arg Gly Thr Pro Pro Asn Val Val 65 70 75 80 Glu Thr Asp Ala Lys Thr Trp Leu Arg Leu Ala Pro Gly Gln Thr Thr 85 90 95 Phe Asp Ala Glu Phe Glu Ser Gly Lys Ile Ser Ala Ser Gly Thr Arg 100 105 110 Ala Lys Glu Ile Ala Asp Trp Leu Pro Val Val Lys Leu 115 120 125 <210> 1093 <211> 1305 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1282) <223> RXC01088 <400> 1093 tgccttgagt ctaattctcc cgcccgtgcg atgggtttaa gctggactga taaacctttt 60 gtgaaccgaa ttttttaact gatttgaaga agcgagaata atg gga ctg tgg atc 115 Met Gly Leu Trp Ile 1 5 gat gca acc gct ggc gtt gca ggg gat atg ttg ctg gga gca ctc att 163 Asp Ala Thr Ala Gly Val Ala Gly Asp Met Leu Leu Gly Ala Leu Ile 10 15 20 gat gca ggt gca gaa cta gaa aaa atc caa cag gtt gtg gaa gca gtc 211 Asp Ala Gly Ala Glu Leu Glu Lys Ile Gln Gln Val Val Glu Ala Val 25 30 35 atc ccc ggt gac gtg ctc ttg cgc acc gaa gag gta gtg cgc caa ggc 259 Ile Pro Gly Asp Val Leu Leu Arg Thr Glu Glu Val Val Arg Gln Gly 40 45 50 caa cga ggc atc aag ctg cat gtg gac gca caa cat gaa cac cat cat 307 Gln Arg Gly Ile Lys Leu His Val Asp Ala Gln His Glu His His His 55 60 65 cac cgc cac tta agc acc att aaa gaa ctg ctt gtc aat gct gac atc 355 His Arg His Leu Ser Thr Ile Lys Glu Leu Leu Val Asn Ala Asp Ile 70 75 80 85 cct gaa caa acc aag cag gat gcc tta ggc gtt ttt gaa ctc atc gct 403 Pro Glu Gln Thr Lys Gln Asp Ala Leu Gly Val Phe Glu Leu Ile Ala 90 95 100 atc gct gaa gga aaa gtc cac ggc atc gag ccg gag aaa atc cac ttc 451 Ile Ala Glu Gly Lys Val His Gly Ile Glu Pro Glu Lys Ile His Phe 105 110 115 cat gag gta gga gct tgg gat tcc atc gca gac att gtg ggt gtg tgc 499 His Glu Val Gly Ala Trp Asp Ser Ile Ala Asp Ile Val Gly Val Cys 120 125 130 gaa gcg atc agg cag ctt aac cca ggt ttg att gct gca tct ccg att 547 Glu Ala Ile Arg Gln Leu Asn Pro Gly Leu Ile Ala Ala Ser Pro Ile 135 140 145 gct tta gga ttc gga cgc atc aag gca gct cac gga gat att cca gtg 595 Ala Leu Gly Phe Gly Arg Ile Lys Ala Ala His Gly Asp Ile Pro Val 150 155 160 165 cca gtt cca gcc gtg gca gag ctg gtg aaa ggc tgg ccc acc caa acc 643 Pro Val Pro Ala Val Ala Glu Leu Val Lys Gly Trp Pro Thr Gln Thr 170 175 180 gga gct ctt atg gag agc acc gaa cct gtt ggt gaa tta gcc acc cca 691 Gly Ala Leu Met Glu Ser Thr Glu Pro Val Gly Glu Leu Ala Thr Pro 185 190 195 act ggt gtt gcg ttg atc cgt cac ttt gcc acc caa gat ggc cct ttc 739 Thr Gly Val Ala Leu Ile Arg His Phe Ala Thr Gln Asp Gly Pro Phe 200 205 210 cca ggt ggc atc atc aat gaa gtt ggc att ggt gca gga aca aaa gat 787 Pro Gly Gly Ile Ile Asn Glu Val Gly Ile Gly Ala Gly Thr Lys Asp 215 220 225 aca gaa ggc cgt cca aat ata gtg cgc gca att ttg ttc aac acc tct 835 Thr Glu Gly Arg Pro Asn Ile Val Arg Ala Ile Leu Phe Asn Thr Ser 230 235 240 245 agg agt aac cca gat acc cgc aca ctg gtg caa tta gaa gcc aat gtt 883 Arg Ser Asn Pro Asp Thr Arg Thr Leu Val Gln Leu Glu Ala Asn Val 250 255 260 gat gat caa gac cca cgg ctg tgg cca gga gta ata gag atc ctc ttt 931 Asp Asp Gln Asp Pro Arg Leu Trp Pro Gly Val Ile Glu Ile Leu Phe 265 270 275 gcc gct ggc gca gta gat gca tgg ctg act cca att ttg atg aag aag 979 Ala Ala Gly Ala Val Asp Ala Trp Leu Thr Pro Ile Leu Met Lys Lys 280 285 290 ggc cgt cct gca cat agg gtg tca gca ttg gtg gat agc tcc gag gtg 1027 Gly Arg Pro Ala His Arg Val Ser Ala Leu Val Asp Ser Ser Glu Val 295 300 305 gaa gca gtg aaa acc gca tta ttt gca gcc acc acg act ttt ggg atc 1075 Glu Ala Val Lys Thr Ala Leu Phe Ala Ala Thr Thr Thr Phe Gly Ile 310 315 320 325 aga tca tgg gaa gtc gaa cga gaa ggc ttg gac cgt cgt ttc gaa caa 1123 Arg Ser Trp Glu Val Glu Arg Glu Gly Leu Asp Arg Arg Phe Glu Gln 330 335 340 gtc gag gtg gac gga cac acc atc aac atc aaa atc ggt tcc cgt gat 1171 Val Glu Val Asp Gly His Thr Ile Asn Ile Lys Ile Gly Ser Arg Asp 345 350 355 gat caa gta atc agt gca cag tcc gag ttt gaa gat att cgg tct gca 1219 Asp Gln Val Ile Ser Ala Gln Ser Glu Phe Glu Asp Ile Arg Ser Ala 360 365 370 gcg gtg gcc ttg gga att tca gag cgg gaa gtt gtg gca aga att ccg 1267 Ala Val Ala Leu Gly Ile Ser Glu Arg Glu Val Val Ala Arg Ile Pro 375 380 385 caa ggc acc acc gag taacaaccaa aaggtcgact gct 1305 Gln Gly Thr Thr Glu 390 <210> 1094 <211> 394 <212> PRT <213> Corynebacterium glutamicum <400> 1094 Met Gly Leu Trp Ile Asp Ala Thr Ala Gly Val Ala Gly Asp Met Leu 1 5 10 15 Leu Gly Ala Leu Ile Asp Ala Gly Ala Glu Leu Glu Lys Ile Gln Gln 20 25 30 Val Val Glu Ala Val Ile Pro Gly Asp Val Leu Leu Arg Thr Glu Glu 35 40 45 Val Val Arg Gln Gly Gln Arg Gly Ile Lys Leu His Val Asp Ala Gln 50 55 60 His Glu His His His His Arg His Leu Ser Thr Ile Lys Glu Leu Leu 65 70 75 80 Val Asn Ala Asp Ile Pro Glu Gln Thr Lys Gln Asp Ala Leu Gly Val 85 90 95 Phe Glu Leu Ile Ala Ile Ala Glu Gly Lys Val His Gly Ile Glu Pro 100 105 110 Glu Lys Ile His Phe His Glu Val Gly Ala Trp Asp Ser Ile Ala Asp 115 120 125 Ile Val Gly Val Cys Glu Ala Ile Arg Gln Leu Asn Pro Gly Leu Ile 130 135 140 Ala Ala Ser Pro Ile Ala Leu Gly Phe Gly Arg Ile Lys Ala Ala His 145 150 155 160 Gly Asp Ile Pro Val Pro Val Pro Ala Val Ala Glu Leu Val Lys Gly 165 170 175 Trp Pro Thr Gln Thr Gly Ala Leu Met Glu Ser Thr Glu Pro Val Gly 180 185 190 Glu Leu Ala Thr Pro Thr Gly Val Ala Leu Ile Arg His Phe Ala Thr 195 200 205 Gln Asp Gly Pro Phe Pro Gly Gly Ile Ile Asn Glu Val Gly Ile Gly 210 215 220 Ala Gly Thr Lys Asp Thr Glu Gly Arg Pro Asn Ile Val Arg Ala Ile 225 230 235 240 Leu Phe Asn Thr Ser Arg Ser Asn Pro Asp Thr Arg Thr Leu Val Gln 245 250 255 Leu Glu Ala Asn Val Asp Asp Gln Asp Pro Arg Leu Trp Pro Gly Val 260 265 270 Ile Glu Ile Leu Phe Ala Ala Gly Ala Val Asp Ala Trp Leu Thr Pro 275 280 285 Ile Leu Met Lys Lys Gly Arg Pro Ala His Arg Val Ser Ala Leu Val 290 295 300 Asp Ser Ser Glu Val Glu Ala Val Lys Thr Ala Leu Phe Ala Ala Thr 305 310 315 320 Thr Thr Phe Gly Ile Arg Ser Trp Glu Val Glu Arg Glu Gly Leu Asp 325 330 335 Arg Arg Phe Glu Gln Val Glu Val Asp Gly His Thr Ile Asn Ile Lys 340 345 350 Ile Gly Ser Arg Asp Asp Gln Val Ile Ser Ala Gln Ser Glu Phe Glu 355 360 365 Asp Ile Arg Ser Ala Ala Val Ala Leu Gly Ile Ser Glu Arg Glu Val 370 375 380 Val Ala Arg Ile Pro Gln Gly Thr Thr Glu 385 390 <210> 1095 <211> 1419 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1396) <223> RXC02624 <400> 1095 acccggtcag atccgacgtc gccggccaaa accgcaagca cctgcgcaaa cgccacagaa 60 ggcagctcag caatcaaagt tgctgcgttt ccttccaacc gtg ctg att ccg cat 115 Val Leu Ile Pro His 1 5 ggc gtg gcg gtg ctt ttg gtt att att ctc gcc gta gcc tcc cta atg 163 Gly Val Ala Val Leu Leu Val Ile Ile Leu Ala Val Ala Ser Leu Met 10 15 20 ttc acc aat tct tca atg gtg aat ctt tcg gca acg att gca cag ctg 211 Phe Thr Asn Ser Ser Met Val Asn Leu Ser Ala Thr Ile Ala Gln Leu 25 30 35 tgg ctt tcc cta aat ctc ggt gcg gtg gac ggc agt ggg gaa gtg atc 259 Trp Leu Ser Leu Asn Leu Gly Ala Val Asp Gly Ser Gly Glu Val Ile 40 45 50 tca gta ctg ccc acg ctt ccc ggc ttt ata ttc ctc tgg gcc atc gcc 307 Ser Val Leu Pro Thr Leu Pro Gly Phe Ile Phe Leu Trp Ala Ile Ala 55 60 65 gcg cgc atc cac cgc gca gtc aaa gat cgt gtc agc atc gcc gac tta 355 Ala Arg Ile His Arg Ala Val Lys Asp Arg Val Ser Ile Ala Asp Leu 70 75 80 85 ggc gtc ctc gca gca ctc gtc ctc ggc atc ccg ctt gcg ctc acc gcc 403 Gly Val Leu Ala Ala Leu Val Leu Gly Ile Pro Leu Ala Leu Thr Ala 90 95 100 atc gca gcg ttc atg ctt ttc gac gcc tcc agc gtc ctc aac gtc gag 451 Ile Ala Ala Phe Met Leu Phe Asp Ala Ser Ser Val Leu Asn Val Glu 105 110 115 gtc ccg cca atc acg cgc ctc cta cgc gtg atg ttg ttc cac ctc agc 499 Val Pro Pro Ile Thr Arg Leu Leu Arg Val Met Leu Phe His Leu Ser 120 125 130 gcc ctc ttc ctc ggc atg ggg cca cgc ctg tgg cag gcg ttg gcg cgc 547 Ala Leu Phe Leu Gly Met Gly Pro Arg Leu Trp Gln Ala Leu Ala Arg 135 140 145 cgc tac ggt gct cca gaa tgg ctt atc gac gcc atc acc caa gct ttc 595 Arg Tyr Gly Ala Pro Glu Trp Leu Ile Asp Ala Ile Thr Gln Ala Phe 150 155 160 165 cgc ttc ctc atc gca ttt gga aca gtc tcc ttg gtt tcc gtg ctc gtg 643 Arg Phe Leu Ile Ala Phe Gly Thr Val Ser Leu Val Ser Val Leu Val 170 175 180 atg acc gcg atc aac cac agt gca ttc acc gcg acc atg cag ggt tac 691 Met Thr Ala Ile Asn His Ser Ala Phe Thr Ala Thr Met Gln Gly Tyr 185 190 195 gac gac tcc gcc tct gtt gtg gcc ttg atc gtc ctg agc att ctg tat 739 Asp Asp Ser Ala Ser Val Val Ala Leu Ile Val Leu Ser Ile Leu Tyr 200 205 210 ctg ccc aac atg atg atc ttt gcg atg ggc aat ctg atc ggc tca ccc 787 Leu Pro Asn Met Met Ile Phe Ala Met Gly Asn Leu Ile Gly Ser Pro 215 220 225 ctt tac ttc ggt gac gcc tcc atc agc gtc ttc agc gtg cat tcc gtt 835 Leu Tyr Phe Gly Asp Ala Ser Ile Ser Val Phe Ser Val His Ser Val 230 235 240 245 cca ttg cca ccg ctt ccc atc ctc gca gct ctc ccc agc gaa gcc ctc 883 Pro Leu Pro Pro Leu Pro Ile Leu Ala Ala Leu Pro Ser Glu Ala Leu 250 255 260 tca tgg gca gtg gcc tta ctg gtc atc cct gca att att gcc acc tgg 931 Ser Trp Ala Val Ala Leu Leu Val Ile Pro Ala Ile Ile Ala Thr Trp 265 270 275 gtc tgc gtg aga aac ccc atg cgc ctt gcc gtg aac aca aca gca gca 979 Val Cys Val Arg Asn Pro Met Arg Leu Ala Val Asn Thr Thr Ala Ala 280 285 290 gtc att tca gca ctg tgt ttc ctc gtc ctg gca gtt ttc gcc ggc gga 1027 Val Ile Ser Ala Leu Cys Phe Leu Val Leu Ala Val Phe Ala Gly Gly 295 300 305 acc ttg ggc gta tac aac tac gtc gga ctc aac ctc ctg gcg tca gtt 1075 Thr Leu Gly Val Tyr Asn Tyr Val Gly Leu Asn Leu Leu Ala Ser Val 310 315 320 325 ggc cta gtt ttc gtc tat ttc gcc ctc gtt gga ctc ctc atc gcc gga 1123 Gly Leu Val Phe Val Tyr Phe Ala Leu Val Gly Leu Leu Ile Ala Gly 330 335 340 atc gac aag ctg cgc aac cct gta gaa gtt aag tct gtt aag gct gtg 1171 Ile Asp Lys Leu Arg Asn Pro Val Glu Val Lys Ser Val Lys Ala Val 345 350 355 gct gtt gtg gag ccc gag cct gaa gaa gtt gaa gag gac gaa gag gag 1219 Ala Val Val Glu Pro Glu Pro Glu Glu Val Glu Glu Asp Glu Glu Glu 360 365 370 cat gtt gaa gaa gaa gta gat gag gag gaa gag gaa gtt gag gaa ggg 1267 His Val Glu Glu Glu Val Asp Glu Glu Glu Glu Glu Val Glu Glu Gly 375 380 385 gta gaa gag gtc gaa gaa gac gac gca gag gat cct gaa gag aat cct 1315 Val Glu Glu Val Glu Glu Asp Asp Ala Glu Asp Pro Glu Glu Asn Pro 390 395 400 405 gaa gag gaa gaa tcc gac gaa gaa att gag aca gaa act gag gct gaa 1363 Glu Glu Glu Glu Ser Asp Glu Glu Ile Glu Thr Glu Thr Glu Ala Glu 410 415 420 gaa acc aat gat ggt tcc gag gcc gaa gac cgt taacatatct gttgtgaatt 1416 Glu Thr Asn Asp Gly Ser Glu Ala Glu Asp Arg 425 430 ctg 1419 <210> 1096 <211> 432 <212> PRT <213> Corynebacterium glutamicum <400> 1096 Val Leu Ile Pro His Gly Val Ala Val Leu Leu Val Ile Ile Leu Ala 1 5 10 15 Val Ala Ser Leu Met Phe Thr Asn Ser Ser Met Val Asn Leu Ser Ala 20 25 30 Thr Ile Ala Gln Leu Trp Leu Ser Leu Asn Leu Gly Ala Val Asp Gly 35 40 45 Ser Gly Glu Val Ile Ser Val Leu Pro Thr Leu Pro Gly Phe Ile Phe 50 55 60 Leu Trp Ala Ile Ala Ala Arg Ile His Arg Ala Val Lys Asp Arg Val 65 70 75 80 Ser Ile Ala Asp Leu Gly Val Leu Ala Ala Leu Val Leu Gly Ile Pro 85 90 95 Leu Ala Leu Thr Ala Ile Ala Ala Phe Met Leu Phe Asp Ala Ser Ser 100 105 110 Val Leu Asn Val Glu Val Pro Pro Ile Thr Arg Leu Leu Arg Val Met 115 120 125 Leu Phe His Leu Ser Ala Leu Phe Leu Gly Met Gly Pro Arg Leu Trp 130 135 140 Gln Ala Leu Ala Arg Arg Tyr Gly Ala Pro Glu Trp Leu Ile Asp Ala 145 150 155 160 Ile Thr Gln Ala Phe Arg Phe Leu Ile Ala Phe Gly Thr Val Ser Leu 165 170 175 Val Ser Val Leu Val Met Thr Ala Ile Asn His Ser Ala Phe Thr Ala 180 185 190 Thr Met Gln Gly Tyr Asp Asp Ser Ala Ser Val Val Ala Leu Ile Val 195 200 205 Leu Ser Ile Leu Tyr Leu Pro Asn Met Met Ile Phe Ala Met Gly Asn 210 215 220 Leu Ile Gly Ser Pro Leu Tyr Phe Gly Asp Ala Ser Ile Ser Val Phe 225 230 235 240 Ser Val His Ser Val Pro Leu Pro Pro Leu Pro Ile Leu Ala Ala Leu 245 250 255 Pro Ser Glu Ala Leu Ser Trp Ala Val Ala Leu Leu Val Ile Pro Ala 260 265 270 Ile Ile Ala Thr Trp Val Cys Val Arg Asn Pro Met Arg Leu Ala Val 275 280 285 Asn Thr Thr Ala Ala Val Ile Ser Ala Leu Cys Phe Leu Val Leu Ala 290 295 300 Val Phe Ala Gly Gly Thr Leu Gly Val Tyr Asn Tyr Val Gly Leu Asn 305 310 315 320 Leu Leu Ala Ser Val Gly Leu Val Phe Val Tyr Phe Ala Leu Val Gly 325 330 335 Leu Leu Ile Ala Gly Ile Asp Lys Leu Arg Asn Pro Val Glu Val Lys 340 345 350 Ser Val Lys Ala Val Ala Val Val Glu Pro Glu Pro Glu Glu Val Glu 355 360 365 Glu Asp Glu Glu Glu His Val Glu Glu Glu Val Asp Glu Glu Glu Glu 370 375 380 Glu Val Glu Glu Gly Val Glu Glu Val Glu Glu Asp Asp Ala Glu Asp 385 390 395 400 Pro Glu Glu Asn Pro Glu Glu Glu Glu Ser Asp Glu Glu Ile Glu Thr 405 410 415 Glu Thr Glu Ala Glu Glu Thr Asn Asp Gly Ser Glu Ala Glu Asp Arg 420 425 430 <210> 1097 <211> 603 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(580) <223> RXC02665 <400> 1097 caaggcgacc caatggcgtt taaagtaaca acccccattg atatgatgct ggcacaacgc 60 atcaccgacg aagccgaacc cacaatattt gaggtaccag gtg act aac cca atc 115 Val Thr Asn Pro Ile 1 5 atc ccc cgc gta gga atc gcc aca gac gcc cac caa atc gaa gcg gga 163 Ile Pro Arg Val Gly Ile Ala Thr Asp Ala His Gln Ile Glu Ala Gly 10 15 20 aaa ccc tgc tgg atc gcc tgc ctc ctc ttt gaa ggc gtc gac ggc tgc 211 Lys Pro Cys Trp Ile Ala Cys Leu Leu Phe Glu Gly Val Asp Gly Cys 25 30 35 gaa ggc cac tcc gac ggt gat gtt gta gct cat gca att gtg gat gct 259 Glu Gly His Ser Asp Gly Asp Val Val Ala His Ala Ile Val Asp Ala 40 45 50 ctc ctt tct gcc tct ggt ctg ggg gat ttg ggc tct ttc gtt ggt gtg 307 Leu Leu Ser Ala Ser Gly Leu Gly Asp Leu Gly Ser Phe Val Gly Val 55 60 65 ggg aga cct gaa tac gat ggt gtt tct ggt aca cag ttg ttg aag gaa 355 Gly Arg Pro Glu Tyr Asp Gly Val Ser Gly Thr Gln Leu Leu Lys Glu 70 75 80 85 gtt cgg gag ctg ctt tcg gca cac ggg tac gtc att gga aat gtc gcc 403 Val Arg Glu Leu Leu Ser Ala His Gly Tyr Val Ile Gly Asn Val Ala 90 95 100 gcc caa ctg gtt ggc caa acc ccc aaa ttt gga ccc cgc cgc gaa gaa 451 Ala Gln Leu Val Gly Gln Thr Pro Lys Phe Gly Pro Arg Arg Glu Glu 105 110 115 gca caa caa gtc atc tcc gaa atc atc ggc gca cca tgc tca ctg tct 499 Ala Gln Gln Val Ile Ser Glu Ile Ile Gly Ala Pro Cys Ser Leu Ser 120 125 130 gcc acc acc act gat cac atg gga ttc act ggt cgc agc gag ggt cgt 547 Ala Thr Thr Thr Asp His Met Gly Phe Thr Gly Arg Ser Glu Gly Arg 135 140 145 gca tcg gta gca acg gca gtg gtg tgg aag gct taagttttct gtagggattg 600 Ala Ser Val Ala Thr Ala Val Val Trp Lys Ala 150 155 160 ggc 603 <210> 1098 <211> 160 <212> PRT <213> Corynebacterium glutamicum <400> 1098 Val Thr Asn Pro Ile Ile Pro Arg Val Gly Ile Ala Thr Asp Ala His 1 5 10 15 Gln Ile Glu Ala Gly Lys Pro Cys Trp Ile Ala Cys Leu Leu Phe Glu 20 25 30 Gly Val Asp Gly Cys Glu Gly His Ser Asp Gly Asp Val Val Ala His 35 40 45 Ala Ile Val Asp Ala Leu Leu Ser Ala Ser Gly Leu Gly Asp Leu Gly 50 55 60 Ser Phe Val Gly Val Gly Arg Pro Glu Tyr Asp Gly Val Ser Gly Thr 65 70 75 80 Gln Leu Leu Lys Glu Val Arg Glu Leu Leu Ser Ala His Gly Tyr Val 85 90 95 Ile Gly Asn Val Ala Ala Gln Leu Val Gly Gln Thr Pro Lys Phe Gly 100 105 110 Pro Arg Arg Glu Glu Ala Gln Gln Val Ile Ser Glu Ile Ile Gly Ala 115 120 125 Pro Cys Ser Leu Ser Ala Thr Thr Thr Asp His Met Gly Phe Thr Gly 130 135 140 Arg Ser Glu Gly Arg Ala Ser Val Ala Thr Ala Val Val Trp Lys Ala 145 150 155 160 <210> 1099 <211> 1689 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1666) <223> RXC02770 <400> 1099 tcgccggggc aaaaaccgta taattacagt cctattacga ttcggggaaa ggctgggtac 60 ttcacacatg ttgtttcgga agtcacgcag cgcggtaatc atg ttg gtt gca gcg 115 Met Leu Val Ala Ala 1 5 tta gtg atg aca agc tgt ggt gat ggg gaa ccg gaa cca acc agc cac 163 Leu Val Met Thr Ser Cys Gly Asp Gly Glu Pro Glu Pro Thr Ser His 10 15 20 caa aca agc ctt ttc ggc tac gca gtt aac tct tcg ctg gct aca acc 211 Gln Thr Ser Leu Phe Gly Tyr Ala Val Asn Ser Ser Leu Ala Thr Thr 25 30 35 aac gcg gcg tcg ctg ttg gga gtg gct aat gat gct ggt ctt ttg gct 259 Asn Ala Ala Ser Leu Leu Gly Val Ala Asn Asp Ala Gly Leu Leu Ala 40 45 50 gcc aga gtg tat ccg ggt gtg tat gtt cag ggt cct tct ggg cag atg 307 Ala Arg Val Tyr Pro Gly Val Tyr Val Gln Gly Pro Ser Gly Gln Met 55 60 65 att ccc aac act gat ctt gct tcc acg cag gta ttg ccg ggt att aac 355 Ile Pro Asn Thr Asp Leu Ala Ser Thr Gln Val Leu Pro Gly Ile Asn 70 75 80 85 cgc cag gtg att tac act atc aat gaa gat gcc acc tac tca gat ggt 403 Arg Gln Val Ile Tyr Thr Ile Asn Glu Asp Ala Thr Tyr Ser Asp Gly 90 95 100 cag cct gtg gtg tgt gat gat ttt ctg ctc tct gcg aca gct ggg cag 451 Gln Pro Val Val Cys Asp Asp Phe Leu Leu Ser Ala Thr Ala Gly Gln 105 110 115 atg ccg gaa ctg ttc cag tcc cat gtg cca ttg acc tcg cag att gag 499 Met Pro Glu Leu Phe Gln Ser His Val Pro Leu Thr Ser Gln Ile Glu 120 125 130 cga gtg gac tgt gta tct ggt tct aaa gta gcc acc gtg gtg ttc aag 547 Arg Val Asp Cys Val Ser Gly Ser Lys Val Ala Thr Val Val Phe Lys 135 140 145 gaa gac ctc ggt gag cgt tgg cgt tat ctt ttt gag cag ggc gat ttg 595 Glu Asp Leu Gly Glu Arg Trp Arg Tyr Leu Phe Glu Gln Gly Asp Leu 150 155 160 165 ttg cca gcc cat gcc gtt gct tcc aaa gca ggt atg acc ttg gag gag 643 Leu Pro Ala His Ala Val Ala Ser Lys Ala Gly Met Thr Leu Glu Glu 170 175 180 ctt aat cag gcg ttg aag gat aag gat cct gaa gcg ttg act gaa cct 691 Leu Asn Gln Ala Leu Lys Asp Lys Asp Pro Glu Ala Leu Thr Glu Pro 185 190 195 gct cgt gtg tgg agc gaa ggt ttc cag ctg tcc cag ttt gat cca gag 739 Ala Arg Val Trp Ser Glu Gly Phe Gln Leu Ser Gln Phe Asp Pro Glu 200 205 210 ctg cag acg gct ttt ggc ccg tac aag gtg gat tct gtg ggt gaa ttc 787 Leu Gln Thr Ala Phe Gly Pro Tyr Lys Val Asp Ser Val Gly Glu Phe 215 220 225 ggc gaa gtc aag ctg gta cgc aat gag ttt tac agt ggc gac cag gcg 835 Gly Glu Val Lys Leu Val Arg Asn Glu Phe Tyr Ser Gly Asp Gln Ala 230 235 240 245 gtt gaa gca gaa atc acg atg tgg cct aaa ggc tcg gat ctc agc gcc 883 Val Glu Ala Glu Ile Thr Met Trp Pro Lys Gly Ser Asp Leu Ser Ala 250 255 260 att gcg gat aat gga aac ctt cag atc gca cat gtt gtg gcg tgg gag 931 Ile Ala Asp Asn Gly Asn Leu Gln Ile Ala His Val Val Ala Trp Glu 265 270 275 agc gag ccg tgg gta aat cgc gat gac cca ttg aat cct tat gac att 979 Ser Glu Pro Trp Val Asn Arg Asp Asp Pro Leu Asn Pro Tyr Asp Ile 280 285 290 aag gaa gag gtc ggt gtt ttg act gag cag ctc acc ttg gcc agt gcc 1027 Lys Glu Glu Val Gly Val Leu Thr Glu Gln Leu Thr Leu Ala Ser Ala 295 300 305 ggt gtg ttt tac gct gcg gag gcc cgg cag gcg ttt gcg gcc tgc gtt 1075 Gly Val Phe Tyr Ala Ala Glu Ala Arg Gln Ala Phe Ala Ala Cys Val 310 315 320 325 gac cag gaa gcg gtg gct gcg gcg tcg tca agc atc tct gga atc gat 1123 Asp Gln Glu Ala Val Ala Ala Ala Ser Ser Ser Ile Ser Gly Ile Asp 330 335 340 gtg cct gcc gta ggt gtg cac tcg gtg cgt cac caa aat ccg gtc gtg 1171 Val Pro Ala Val Gly Val His Ser Val Arg His Gln Asn Pro Val Val 345 350 355 cac caa atc ggt gat ctg cca gca cag cac atg gcg gtg gat att aat 1219 His Gln Ile Gly Asp Leu Pro Ala Gln His Met Ala Val Asp Ile Asn 360 365 370 gcc gca tca gcg ttg gcg ggt caa tcc atc cgc att ggc tac gac gga 1267 Ala Ala Ser Ala Leu Ala Gly Gln Ser Ile Arg Ile Gly Tyr Asp Gly 375 380 385 ccc gat gag cgc aag gct gca atg gtg gag gcg att cgc caa agt tgt 1315 Pro Asp Glu Arg Lys Ala Ala Met Val Glu Ala Ile Arg Gln Ser Cys 390 395 400 405 gag cct gcc ggt atc acc gtt atc gat gcg tcg cag gag gct gtt agt 1363 Glu Pro Ala Gly Ile Thr Val Ile Asp Ala Ser Gln Glu Ala Val Ser 410 415 420 ctt aat gat ctc agt cga acc gaa gtc agt gaa tgg ggc tat gag cag 1411 Leu Asn Asp Leu Ser Arg Thr Glu Val Ser Glu Trp Gly Tyr Glu Gln 425 430 435 tac ttc gaa ggg aca ctt gac gct gtt ctg cgt aca gtg gat cca cat 1459 Tyr Phe Glu Gly Thr Leu Asp Ala Val Leu Arg Thr Val Asp Pro His 440 445 450 cgg gag tat gaa aat gcc aat acc att gga act gat gcg gag tcg acg 1507 Arg Glu Tyr Glu Asn Ala Asn Thr Ile Gly Thr Asp Ala Glu Ser Thr 455 460 465 agg cgc act gaa gaa caa ttg tgg gct gaa gtc cca tca att cca cta 1555 Arg Arg Thr Glu Glu Gln Leu Trp Ala Glu Val Pro Ser Ile Pro Leu 470 475 480 485 gca gcg caa ccc cga gtg ttt gtg ata gat cgc aca gtc ggt aac gtt 1603 Ala Ala Gln Pro Arg Val Phe Val Ile Asp Arg Thr Val Gly Asn Val 490 495 500 gtt gtt aat aca gac cta gcc ggt atc gga tgg aac atg gac cgt tgg 1651 Val Val Asn Thr Asp Leu Ala Gly Ile Gly Trp Asn Met Asp Arg Trp 505 510 515 tcc aga agt gag gaa taagtagtga gcgaacaagc tct 1689 Ser Arg Ser Glu Glu 520 <210> 1100 <211> 522 <212> PRT <213> Corynebacterium glutamicum <400> 1100 Met Leu Val Ala Ala Leu Val Met Thr Ser Cys Gly Asp Gly Glu Pro 1 5 10 15 Glu Pro Thr Ser His Gln Thr Ser Leu Phe Gly Tyr Ala Val Asn Ser 20 25 30 Ser Leu Ala Thr Thr Asn Ala Ala Ser Leu Leu Gly Val Ala Asn Asp 35 40 45 Ala Gly Leu Leu Ala Ala Arg Val Tyr Pro Gly Val Tyr Val Gln Gly 50 55 60 Pro Ser Gly Gln Met Ile Pro Asn Thr Asp Leu Ala Ser Thr Gln Val 65 70 75 80 Leu Pro Gly Ile Asn Arg Gln Val Ile Tyr Thr Ile Asn Glu Asp Ala 85 90 95 Thr Tyr Ser Asp Gly Gln Pro Val Val Cys Asp Asp Phe Leu Leu Ser 100 105 110 Ala Thr Ala Gly Gln Met Pro Glu Leu Phe Gln Ser His Val Pro Leu 115 120 125 Thr Ser Gln Ile Glu Arg Val Asp Cys Val Ser Gly Ser Lys Val Ala 130 135 140 Thr Val Val Phe Lys Glu Asp Leu Gly Glu Arg Trp Arg Tyr Leu Phe 145 150 155 160 Glu Gln Gly Asp Leu Leu Pro Ala His Ala Val Ala Ser Lys Ala Gly 165 170 175 Met Thr Leu Glu Glu Leu Asn Gln Ala Leu Lys Asp Lys Asp Pro Glu 180 185 190 Ala Leu Thr Glu Pro Ala Arg Val Trp Ser Glu Gly Phe Gln Leu Ser 195 200 205 Gln Phe Asp Pro Glu Leu Gln Thr Ala Phe Gly Pro Tyr Lys Val Asp 210 215 220 Ser Val Gly Glu Phe Gly Glu Val Lys Leu Val Arg Asn Glu Phe Tyr 225 230 235 240 Ser Gly Asp Gln Ala Val Glu Ala Glu Ile Thr Met Trp Pro Lys Gly 245 250 255 Ser Asp Leu Ser Ala Ile Ala Asp Asn Gly Asn Leu Gln Ile Ala His 260 265 270 Val Val Ala Trp Glu Ser Glu Pro Trp Val Asn Arg Asp Asp Pro Leu 275 280 285 Asn Pro Tyr Asp Ile Lys Glu Glu Val Gly Val Leu Thr Glu Gln Leu 290 295 300 Thr Leu Ala Ser Ala Gly Val Phe Tyr Ala Ala Glu Ala Arg Gln Ala 305 310 315 320 Phe Ala Ala Cys Val Asp Gln Glu Ala Val Ala Ala Ala Ser Ser Ser 325 330 335 Ile Ser Gly Ile Asp Val Pro Ala Val Gly Val His Ser Val Arg His 340 345 350 Gln Asn Pro Val Val His Gln Ile Gly Asp Leu Pro Ala Gln His Met 355 360 365 Ala Val Asp Ile Asn Ala Ala Ser Ala Leu Ala Gly Gln Ser Ile Arg 370 375 380 Ile Gly Tyr Asp Gly Pro Asp Glu Arg Lys Ala Ala Met Val Glu Ala 385 390 395 400 Ile Arg Gln Ser Cys Glu Pro Ala Gly Ile Thr Val Ile Asp Ala Ser 405 410 415 Gln Glu Ala Val Ser Leu Asn Asp Leu Ser Arg Thr Glu Val Ser Glu 420 425 430 Trp Gly Tyr Glu Gln Tyr Phe Glu Gly Thr Leu Asp Ala Val Leu Arg 435 440 445 Thr Val Asp Pro His Arg Glu Tyr Glu Asn Ala Asn Thr Ile Gly Thr 450 455 460 Asp Ala Glu Ser Thr Arg Arg Thr Glu Glu Gln Leu Trp Ala Glu Val 465 470 475 480 Pro Ser Ile Pro Leu Ala Ala Gln Pro Arg Val Phe Val Ile Asp Arg 485 490 495 Thr Val Gly Asn Val Val Val Asn Thr Asp Leu Ala Gly Ile Gly Trp 500 505 510 Asn Met Asp Arg Trp Ser Arg Ser Glu Glu 515 520 <210> 1101 <211> 408 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(385) <223> RXC02238 <400> 1101 ggcgcttagc caaaacatag agcggtaggg tatgcttatc cgattgagca acctttcccg 60 ctcttaacac tactgtccat atacttttga aaaggtgtca gtg acc aac gtg agc 115 Val Thr Asn Val Ser 1 5 aac gag acc aac gcc acc aag gcc gtc ttc gat ccg cca gtg ggc att 163 Asn Glu Thr Asn Ala Thr Lys Ala Val Phe Asp Pro Pro Val Gly Ile 10 15 20 acc gct cct ccg atc gat gaa ctg ctg gat aag gtc act tcc aag tac 211 Thr Ala Pro Pro Ile Asp Glu Leu Leu Asp Lys Val Thr Ser Lys Tyr 25 30 35 gcc ctc gtg atc ttc gca gcc aag cgt gcg cgc cag atc aac agc ttc 259 Ala Leu Val Ile Phe Ala Ala Lys Arg Ala Arg Gln Ile Asn Ser Phe 40 45 50 tac cat cag gca gat gag gga gta ttc gag ttc atc gga cca ttg gtt 307 Tyr His Gln Ala Asp Glu Gly Val Phe Glu Phe Ile Gly Pro Leu Val 55 60 65 act ccg cag cca ggc gaa aag cca ctt tct att gct ctg cgt gag atc 355 Thr Pro Gln Pro Gly Glu Lys Pro Leu Ser Ile Ala Leu Arg Glu Ile 70 75 80 85 aat gca ggt ctg ttg gac cac gag gaa ggt taaaagacct tataacttca 405 Asn Ala Gly Leu Leu Asp His Glu Glu Gly 90 95 cac 408 <210> 1102 <211> 95 <212> PRT <213> Corynebacterium glutamicum <400> 1102 Val Thr Asn Val Ser Asn Glu Thr Asn Ala Thr Lys Ala Val Phe Asp 1 5 10 15 Pro Pro Val Gly Ile Thr Ala Pro Pro Ile Asp Glu Leu Leu Asp Lys 20 25 30 Val Thr Ser Lys Tyr Ala Leu Val Ile Phe Ala Ala Lys Arg Ala Arg 35 40 45 Gln Ile Asn Ser Phe Tyr His Gln Ala Asp Glu Gly Val Phe Glu Phe 50 55 60 Ile Gly Pro Leu Val Thr Pro Gln Pro Gly Glu Lys Pro Leu Ser Ile 65 70 75 80 Ala Leu Arg Glu Ile Asn Ala Gly Leu Leu Asp His Glu Glu Gly 85 90 95 <210> 1103 <211> 1298 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(1275) <223> RXC01946 <400> 1103 atc cgc aag tac tcc agg ctc gag gaa caa ttc cag tcg ctc ggc ggc 48 Ile Arg Lys Tyr Ser Arg Leu Glu Glu Gln Phe Gln Ser Leu Gly Gly 1 5 10 15 tac gaa gct gac gcc gaa gca gcc cag atc tgc gac aac ctc ggc ctc 96 Tyr Glu Ala Asp Ala Glu Ala Ala Gln Ile Cys Asp Asn Leu Gly Leu 20 25 30 gag gca cgc atc ctc gac cag cag ctt aaa acc ctg tcc ggc ggc cag 144 Glu Ala Arg Ile Leu Asp Gln Gln Leu Lys Thr Leu Ser Gly Gly Gln 35 40 45 cgc cgc cgc gtc gag ttg gcg cag atc ctc ttc gcc gcc acc aac ggc 192 Arg Arg Arg Val Glu Leu Ala Gln Ile Leu Phe Ala Ala Thr Asn Gly 50 55 60 tcc ggc aaa tca aaa acc aca ttg ctt ctc gac gag ccc acc aac cac 240 Ser Gly Lys Ser Lys Thr Thr Leu Leu Leu Asp Glu Pro Thr Asn His 65 70 75 80 ttg gac gca gac tcg atc acc tgg ctc cgt gac ttc ctg gcg aag cac 288 Leu Asp Ala Asp Ser Ile Thr Trp Leu Arg Asp Phe Leu Ala Lys His 85 90 95 gaa ggt gga ctg atc atg att tcg cac gac gtc gaa ctg ctt ggc gcc 336 Glu Gly Gly Leu Ile Met Ile Ser His Asp Val Glu Leu Leu Gly Ala 100 105 110 gta tgt aac aag att tgg tac ctc gac gca gta cgc agc gaa gcc gat 384 Val Cys Asn Lys Ile Trp Tyr Leu Asp Ala Val Arg Ser Glu Ala Asp 115 120 125 gtc tac aac atg ggc ttt agc aaa tac gtc gat gca cgt gca ctc gat 432 Val Tyr Asn Met Gly Phe Ser Lys Tyr Val Asp Ala Arg Ala Leu Asp 130 135 140 gaa gca cgc cga cgc cgt gag cgc gca aac gcc gaa aag aag gcc gga 480 Glu Ala Arg Arg Arg Arg Glu Arg Ala Asn Ala Glu Lys Lys Ala Gly 145 150 155 160 gcc ctc aag gac cag gct gca cgc ctc ggc gcg aaa gca acc aag gct 528 Ala Leu Lys Asp Gln Ala Ala Arg Leu Gly Ala Lys Ala Thr Lys Ala 165 170 175 gcc gca gct aag cag atg atc gcc cgt gcg gaa cga atg atc gac aac 576 Ala Ala Ala Lys Gln Met Ile Ala Arg Ala Glu Arg Met Ile Asp Asn 180 185 190 ctc gac gaa atc cgc gta gct gac cgc gcc gcc aac atc gtt ttc cca 624 Leu Asp Glu Ile Arg Val Ala Asp Arg Ala Ala Asn Ile Val Phe Pro 195 200 205 gaa cca gca ccc tgt gga aaa acc cca ctc aac gcc aag ggc ctg acc 672 Glu Pro Ala Pro Cys Gly Lys Thr Pro Leu Asn Ala Lys Gly Leu Thr 210 215 220 aag atg tac ggc tcc ctc gaa gtc ttc gcc ggc gtc gac cta gcc atc 720 Lys Met Tyr Gly Ser Leu Glu Val Phe Ala Gly Val Asp Leu Ala Ile 225 230 235 240 gac aaa ggc tcc cgc gta gtc gtc ctc gga ttc aac ggt gca ggt aaa 768 Asp Lys Gly Ser Arg Val Val Val Leu Gly Phe Asn Gly Ala Gly Lys 245 250 255 acc acc ctg ctc aaa ctc ctc gcc ggt gtg gaa cgc acc gac ggc gaa 816 Thr Thr Leu Leu Lys Leu Leu Ala Gly Val Glu Arg Thr Asp Gly Glu 260 265 270 ggc ggc atc gtc acc gga tac ggc ctc aaa atc ggc tac ttc gcc cag 864 Gly Gly Ile Val Thr Gly Tyr Gly Leu Lys Ile Gly Tyr Phe Ala Gln 275 280 285 gaa cac gac acc atc gac ccc gac aaa tcc gtc tgg caa aac acc atc 912 Glu His Asp Thr Ile Asp Pro Asp Lys Ser Val Trp Gln Asn Thr Ile 290 295 300 gaa gcc tgc gcc gac gcc gac caa caa agc ctc cgc agc ctc ctc gga 960 Glu Ala Cys Ala Asp Ala Asp Gln Gln Ser Leu Arg Ser Leu Leu Gly 305 310 315 320 tcc ttc atg ttc tcc ggc gaa caa ctc gac caa cca gca gga aca ctc 1008 Ser Phe Met Phe Ser Gly Glu Gln Leu Asp Gln Pro Ala Gly Thr Leu 325 330 335 tcc ggc ggt gaa aaa acc cgc ctc gca ctg gcc acc ctc gtg tcc tcc 1056 Ser Gly Gly Glu Lys Thr Arg Leu Ala Leu Ala Thr Leu Val Ser Ser 340 345 350 cgc gca aac gtc ctg ctt ctc gac gag ccc acc aac aac ctt gac ccg 1104 Arg Ala Asn Val Leu Leu Leu Asp Glu Pro Thr Asn Asn Leu Asp Pro 355 360 365 atc tcc cgc gaa cag gtc ctc gac gca ctg cgc acc tac acc ggc gca 1152 Ile Ser Arg Glu Gln Val Leu Asp Ala Leu Arg Thr Tyr Thr Gly Ala 370 375 380 gtc gtc ctg gtt acc cac gac ccg ggt gca gtc aag gcc ctt gag cca 1200 Val Val Leu Val Thr His Asp Pro Gly Ala Val Lys Ala Leu Glu Pro 385 390 395 400 gaa cgc gtc atc gtg ctt cct gat ggc acc gag gat ctt tgg aat gat 1248 Glu Arg Val Ile Val Leu Pro Asp Gly Thr Glu Asp Leu Trp Asn Asp 405 410 415 cag tac atg gaa atc gtg gaa ttg gcg taggttctaa ggctgtttat 1295 Gln Tyr Met Glu Ile Val Glu Leu Ala 420 425 gct 1298 <210> 1104 <211> 425 <212> PRT <213> Corynebacterium glutamicum <400> 1104 Ile Arg Lys Tyr Ser Arg Leu Glu Glu Gln Phe Gln Ser Leu Gly Gly 1 5 10 15 Tyr Glu Ala Asp Ala Glu Ala Ala Gln Ile Cys Asp Asn Leu Gly Leu 20 25 30 Glu Ala Arg Ile Leu Asp Gln Gln Leu Lys Thr Leu Ser Gly Gly Gln 35 40 45 Arg Arg Arg Val Glu Leu Ala Gln Ile Leu Phe Ala Ala Thr Asn Gly 50 55 60 Ser Gly Lys Ser Lys Thr Thr Leu Leu Leu Asp Glu Pro Thr Asn His 65 70 75 80 Leu Asp Ala Asp Ser Ile Thr Trp Leu Arg Asp Phe Leu Ala Lys His 85 90 95 Glu Gly Gly Leu Ile Met Ile Ser His Asp Val Glu Leu Leu Gly Ala 100 105 110 Val Cys Asn Lys Ile Trp Tyr Leu Asp Ala Val Arg Ser Glu Ala Asp 115 120 125 Val Tyr Asn Met Gly Phe Ser Lys Tyr Val Asp Ala Arg Ala Leu Asp 130 135 140 Glu Ala Arg Arg Arg Arg Glu Arg Ala Asn Ala Glu Lys Lys Ala Gly 145 150 155 160 Ala Leu Lys Asp Gln Ala Ala Arg Leu Gly Ala Lys Ala Thr Lys Ala 165 170 175 Ala Ala Ala Lys Gln Met Ile Ala Arg Ala Glu Arg Met Ile Asp Asn 180 185 190 Leu Asp Glu Ile Arg Val Ala Asp Arg Ala Ala Asn Ile Val Phe Pro 195 200 205 Glu Pro Ala Pro Cys Gly Lys Thr Pro Leu Asn Ala Lys Gly Leu Thr 210 215 220 Lys Met Tyr Gly Ser Leu Glu Val Phe Ala Gly Val Asp Leu Ala Ile 225 230 235 240 Asp Lys Gly Ser Arg Val Val Val Leu Gly Phe Asn Gly Ala Gly Lys 245 250 255 Thr Thr Leu Leu Lys Leu Leu Ala Gly Val Glu Arg Thr Asp Gly Glu 260 265 270 Gly Gly Ile Val Thr Gly Tyr Gly Leu Lys Ile Gly Tyr Phe Ala Gln 275 280 285 Glu His Asp Thr Ile Asp Pro Asp Lys Ser Val Trp Gln Asn Thr Ile 290 295 300 Glu Ala Cys Ala Asp Ala Asp Gln Gln Ser Leu Arg Ser Leu Leu Gly 305 310 315 320 Ser Phe Met Phe Ser Gly Glu Gln Leu Asp Gln Pro Ala Gly Thr Leu 325 330 335 Ser Gly Gly Glu Lys Thr Arg Leu Ala Leu Ala Thr Leu Val Ser Ser 340 345 350 Arg Ala Asn Val Leu Leu Leu Asp Glu Pro Thr Asn Asn Leu Asp Pro 355 360 365 Ile Ser Arg Glu Gln Val Leu Asp Ala Leu Arg Thr Tyr Thr Gly Ala 370 375 380 Val Val Leu Val Thr His Asp Pro Gly Ala Val Lys Ala Leu Glu Pro 385 390 395 400 Glu Arg Val Ile Val Leu Pro Asp Gly Thr Glu Asp Leu Trp Asn Asp 405 410 415 Gln Tyr Met Glu Ile Val Glu Leu Ala 420 425 <210> 1105 <211> 613 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> RXN03171 <400> 1105 atactttgtt ggactggaaa agtggccgtt tggttccctc caagcccaaa ttcgcccgcg 60 cggtcttctt ctgggcggca atgatttaac atgtgaagct atg gac atc acc atc 115 Met Asp Ile Thr Ile 1 5 gtc aac cac cca ctc gtt gct agc cgc cta acc ctg ttg cgc gac gag 163 Val Asn His Pro Leu Val Ala Ser Arg Leu Thr Leu Leu Arg Asp Glu 10 15 20 cgc agc gac aac gca gct ttc cgt gca gca gcc aac gac ctc ggc gcc 211 Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala Asn Asp Leu Gly Ala 25 30 35 atg ctg atc tac gaa gca tcc cga gat ctg gaa gtc gaa cac ttc gac 259 Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu Val Glu His Phe Asp 40 45 50 acc aaa acc ccc gtt gcc atg gct gaa ggt act cgc ctg aag cag cca 307 Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr Arg Leu Lys Gln Pro 55 60 65 ccc atc atc gtt ccc atc atc cgt gca ggt ctc ggc atg atc gac cca 355 Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu Gly Met Ile Asp Pro 70 75 80 85 gcg ctg tcg atg att ccg gat gca cag gtc ggc ttc att ggc ctt gcc 403 Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly Phe Ile Gly Leu Ala 90 95 100 cgc gat gag gaa acc cat gag cca gtc cca tac ctt gag gcg ctg cca 451 Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr Leu Glu Ala Leu Pro 105 110 115 cag gat cta agc aac cag cct gta ttc ctt gtc gat ccc atg ctg gcc 499 Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val Asp Pro Met Leu Ala 120 125 130 acc ggc ggt tcc ctc ctg cac gcg atc cgc ctt ctt gct gat cgt ggc 547 Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu Leu Ala Asp Arg Gly 135 140 145 gcc acc gac atc acc gcc atc tgc atg gtt tct gcg cag cca ggt gtg 595 Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser Ala Gln Pro Gly Val 150 155 160 165 gac gca ttg gcg gaa tct 613 Asp Ala Leu Ala Glu Ser 170 <210> 1106 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 1106 Met Asp Ile Thr Ile Val Asn His Pro Leu Val Ala Ser Arg Leu Thr 1 5 10 15 Leu Leu Arg Asp Glu Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala 20 25 30 Asn Asp Leu Gly Ala Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu 35 40 45 Val Glu His Phe Asp Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr 50 55 60 Arg Leu Lys Gln Pro Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu 65 70 75 80 Gly Met Ile Asp Pro Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly 85 90 95 Phe Ile Gly Leu Ala Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr 100 105 110 Leu Glu Ala Leu Pro Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val 115 120 125 Asp Pro Met Leu Ala Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu 130 135 140 Leu Ala Asp Arg Gly Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser 145 150 155 160 Ala Gln Pro Gly Val Asp Ala Leu Ala Glu Ser 165 170 <210> 1107 <211> 613 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(613) <223> FRXA02857 <400> 1107 atactttgtt ggactggaaa agtggccgtt tggttccctc caagcccaaa ttcgcccgcg 60 cggtcttctt ctgggcggca atgatttaac atgtgaagct atg gac atc acc atc 115 Met Asp Ile Thr Ile 1 5 gtc aac cac cca ctc gtt gct agc cgc cta acc ctg ttg cgc gac gag 163 Val Asn His Pro Leu Val Ala Ser Arg Leu Thr Leu Leu Arg Asp Glu 10 15 20 cgc agc gac aac gca gct ttc cgt gca gca gcc aac gac ctc ggc gcc 211 Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala Asn Asp Leu Gly Ala 25 30 35 atg ctg atc tac gaa gca tcc cga gat ctg gaa gtc gaa cac ttc gac 259 Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu Val Glu His Phe Asp 40 45 50 acc aaa acc ccc gtt gcc atg gct gaa ggt act cgc ctg aag cag cca 307 Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr Arg Leu Lys Gln Pro 55 60 65 ccc atc atc gtt ccc atc atc cgt gca ggt ctc ggc atg atc gac cca 355 Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu Gly Met Ile Asp Pro 70 75 80 85 gcg ctg tcg atg att ccg gat gca cag gtc ggc ttc att ggc ctt gcc 403 Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly Phe Ile Gly Leu Ala 90 95 100 cgc gat gag gaa acc cat gag cca gtc cca tac ctt gag gcg ctg cca 451 Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr Leu Glu Ala Leu Pro 105 110 115 cag gat cta agc aac cag cct gta ttc ctt gtc gat ccc atg ctg gcc 499 Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val Asp Pro Met Leu Ala 120 125 130 acc ggc ggt tcc ctc ctg cac gcg atc cgc ctt ctt gct gat cgt ggc 547 Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu Leu Ala Asp Arg Gly 135 140 145 gcc acc gac atc acc gcc atc tgc atg gtt tct gcg cag cca ggt gtg 595 Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser Ala Gln Pro Gly Val 150 155 160 165 gac gca ttg gcg gaa tct 613 Asp Ala Leu Ala Glu Ser 170 <210> 1108 <211> 171 <212> PRT <213> Corynebacterium glutamicum <400> 1108 Met Asp Ile Thr Ile Val Asn His Pro Leu Val Ala Ser Arg Leu Thr 1 5 10 15 Leu Leu Arg Asp Glu Arg Ser Asp Asn Ala Ala Phe Arg Ala Ala Ala 20 25 30 Asn Asp Leu Gly Ala Met Leu Ile Tyr Glu Ala Ser Arg Asp Leu Glu 35 40 45 Val Glu His Phe Asp Thr Lys Thr Pro Val Ala Met Ala Glu Gly Thr 50 55 60 Arg Leu Lys Gln Pro Pro Ile Ile Val Pro Ile Ile Arg Ala Gly Leu 65 70 75 80 Gly Met Ile Asp Pro Ala Leu Ser Met Ile Pro Asp Ala Gln Val Gly 85 90 95 Phe Ile Gly Leu Ala Arg Asp Glu Glu Thr His Glu Pro Val Pro Tyr 100 105 110 Leu Glu Ala Leu Pro Gln Asp Leu Ser Asn Gln Pro Val Phe Leu Val 115 120 125 Asp Pro Met Leu Ala Thr Gly Gly Ser Leu Leu His Ala Ile Arg Leu 130 135 140 Leu Ala Asp Arg Gly Ala Thr Asp Ile Thr Ala Ile Cys Met Val Ser 145 150 155 160 Ala Gln Pro Gly Val Asp Ala Leu Ala Glu Ser 165 170 <210> 1109 <211> 424 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(424) <223> RXN00450 <400> 1109 tttgcgatga catggatttg gatccttccg aacaattgct gcgcatcgcg gaagaactcg 60 gttttgataa tgatctggct cgggtggtgg gattcgacta gtg ggc gtt tta cct 115 Val Gly Val Leu Pro 1 5 gtg cag gcg cgc atc aaa gac gat gag cgc cgc atg cgc cat gct ttg 163 Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg Met Arg His Ala Leu 10 15 20 gat att gct cgc caa acc cct gag ggg gac gtt ccc gtt ggc gcc gtc 211 Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val Pro Val Gly Ala Val 25 30 35 att tac gcg ccg acc ggg gag atc ctg gcg acc gca acg aac cgt cga 259 Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr Ala Thr Asn Arg Arg 40 45 50 gaa gca gac cgc gat ccc acg gcc cac gcc gaa att att gct tta cga 307 Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu Ile Ile Ala Leu Arg 55 60 65 cga gcc gcc cgc cgt ttt tcc gac ggc tgg cgg ctg agt gac tgc acc 355 Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg Leu Ser Asp Cys Thr 70 75 80 85 gcg gtg gtc acc ttg gag ccc tgc agt atg tgc gcc ggc gcc ttg gtg 403 Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys Ala Gly Ala Leu Val 90 95 100 ggt gct cga atc gga cgc atc 424 Gly Ala Arg Ile Gly Arg Ile 105 <210> 1110 <211> 108 <212> PRT <213> Corynebacterium glutamicum <400> 1110 Val Gly Val Leu Pro Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg 1 5 10 15 Met Arg His Ala Leu Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val 20 25 30 Pro Val Gly Ala Val Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr 35 40 45 Ala Thr Asn Arg Arg Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu 50 55 60 Ile Ile Ala Leu Arg Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg 65 70 75 80 Leu Ser Asp Cys Thr Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys 85 90 95 Ala Gly Ala Leu Val Gly Ala Arg Ile Gly Arg Ile 100 105 <210> 1111 <211> 418 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(418) <223> FRXA00450 <400> 1111 tttgcgatga catggatttg gatccttccg aacaattgct gcgcatcgcg gaagaactcg 60 gttttgataa tgatctggct cgggtggtgg gattcgacta gtg ggc gtt tta cct 115 Val Gly Val Leu Pro 1 5 gtg cag gcg cgc atc aaa gac gat gag cgc cgc atg cgc cat gct ttg 163 Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg Met Arg His Ala Leu 10 15 20 gat att gct cgc caa acc cct gag ggg gac gtt ccc gtt ggc gcc gtc 211 Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val Pro Val Gly Ala Val 25 30 35 att tac gcg ccg acc ggg gag atc ctg gcg acc gca acg aac cgt cga 259 Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr Ala Thr Asn Arg Arg 40 45 50 gaa gca gac cgc gat ccc acg gcc cac gcc gaa att att gct tta cga 307 Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu Ile Ile Ala Leu Arg 55 60 65 cga gcc gcc cgc cgt ttt tcc gac ggc tgg cgg ctg agt gac tgc acc 355 Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg Leu Ser Asp Cys Thr 70 75 80 85 gcg gtg gtc acc ttg gag ccc tgc agt atg tgc gcc ggc gcc ttg gtg 403 Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys Ala Gly Ala Leu Val 90 95 100 ggt gct cga atc gga 418 Gly Ala Arg Ile Gly 105 <210> 1112 <211> 106 <212> PRT <213> Corynebacterium glutamicum <400> 1112 Val Gly Val Leu Pro Val Gln Ala Arg Ile Lys Asp Asp Glu Arg Arg 1 5 10 15 Met Arg His Ala Leu Asp Ile Ala Arg Gln Thr Pro Glu Gly Asp Val 20 25 30 Pro Val Gly Ala Val Ile Tyr Ala Pro Thr Gly Glu Ile Leu Ala Thr 35 40 45 Ala Thr Asn Arg Arg Glu Ala Asp Arg Asp Pro Thr Ala His Ala Glu 50 55 60 Ile Ile Ala Leu Arg Arg Ala Ala Arg Arg Phe Ser Asp Gly Trp Arg 65 70 75 80 Leu Ser Asp Cys Thr Ala Val Val Thr Leu Glu Pro Cys Ser Met Cys 85 90 95 Ala Gly Ala Leu Val Gly Ala Arg Ile Gly 100 105 <210> 1113 <211> 615 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(592) <223> RXA00465 <400> 1113 tccccaacgc gcaccgaact tagccggatc gcagacttca cctggatgtc caccgcagcc 60 caagcgctac cagcgttgat gcgaggtttg agcgcctaac atg act gaa gat gac 115 Met Thr Glu Asp Asp 1 5 tta gat ctg ctg cac cgc aca gta gaa cta gcc acc cag gca ctc aag 163 Leu Asp Leu Leu His Arg Thr Val Glu Leu Ala Thr Gln Ala Leu Lys 10 15 20 cag gga aac agt cct tat gga tcc ctg ctg gtt gat ccc ttc ggc gcg 211 Gln Gly Asn Ser Pro Tyr Gly Ser Leu Leu Val Asp Pro Phe Gly Ala 25 30 35 gtc gtt ttt gaa gac cac aac cga gat gcc gat ggg gat ctg acc aag 259 Val Val Phe Glu Asp His Asn Arg Asp Ala Asp Gly Asp Leu Thr Lys 40 45 50 cac ccg gaa ttc gcc atc gcc aaa tat gcg atc gaa aat tac agt gca 307 His Pro Glu Phe Ala Ile Ala Lys Tyr Ala Ile Glu Asn Tyr Ser Ala 55 60 65 tca gaa cgt gct gcg tgc act gtt tat acc tcg acg gaa cat tgc gcg 355 Ser Glu Arg Ala Ala Cys Thr Val Tyr Thr Ser Thr Glu His Cys Ala 70 75 80 85 atg tgc gcc ggt gcc cat gcg tgg gct gga ctg ggc aaa att tac tgc 403 Met Cys Ala Gly Ala His Ala Trp Ala Gly Leu Gly Lys Ile Tyr Cys 90 95 100 gcc acc aca ggt ggg caa aca gcc gct tgg tac gca aag tgg ggt gca 451 Ala Thr Thr Gly Gly Gln Thr Ala Ala Trp Tyr Ala Lys Trp Gly Ala 105 110 115 gaa tct ggg cct ttg aac ccg att tca gcg gac aaa att agc ccg aac 499 Glu Ser Gly Pro Leu Asn Pro Ile Ser Ala Asp Lys Ile Ser Pro Asn 120 125 130 ata tcc atc gaa gga cct gct tcc aga ttt gag gaa gtc ctg tat gaa 547 Ile Ser Ile Glu Gly Pro Ala Ser Arg Phe Glu Glu Val Leu Tyr Glu 135 140 145 ctg cat cga tgg ttt tat tta ggg cag tct ccg aat aag gct ctt 592 Leu His Arg Trp Phe Tyr Leu Gly Gln Ser Pro Asn Lys Ala Leu 150 155 160 tagcgctggg catgtgactt taa 615 <210> 1114 <211> 164 <212> PRT <213> Corynebacterium glutamicum <400> 1114 Met Thr Glu Asp Asp Leu Asp Leu Leu His Arg Thr Val Glu Leu Ala 1 5 10 15 Thr Gln Ala Leu Lys Gln Gly Asn Ser Pro Tyr Gly Ser Leu Leu Val 20 25 30 Asp Pro Phe Gly Ala Val Val Phe Glu Asp His Asn Arg Asp Ala Asp 35 40 45 Gly Asp Leu Thr Lys His Pro Glu Phe Ala Ile Ala Lys Tyr Ala Ile 50 55 60 Glu Asn Tyr Ser Ala Ser Glu Arg Ala Ala Cys Thr Val Tyr Thr Ser 65 70 75 80 Thr Glu His Cys Ala Met Cys Ala Gly Ala His Ala Trp Ala Gly Leu 85 90 95 Gly Lys Ile Tyr Cys Ala Thr Thr Gly Gly Gln Thr Ala Ala Trp Tyr 100 105 110 Ala Lys Trp Gly Ala Glu Ser Gly Pro Leu Asn Pro Ile Ser Ala Asp 115 120 125 Lys Ile Ser Pro Asn Ile Ser Ile Glu Gly Pro Ala Ser Arg Phe Glu 130 135 140 Glu Val Leu Tyr Glu Leu His Arg Trp Phe Tyr Leu Gly Gln Ser Pro 145 150 155 160 Asn Lys Ala Leu <210> 1115 <211> 1083 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1060) <223> RXA00717 <400> 1115 aagcatcagt taaagccccg actattaaaa tctcctaaaa taggctagaa ttcacgggat 60 tcaatttcat acgttttctc tcaagattaa ggacacttac gtg acc cca ccc gct 115 Val Thr Pro Pro Ala 1 5 cgc cga gat ggc aca ccg gac aag aag cag agc aat cgc tct ggc gga 163 Arg Arg Asp Gly Thr Pro Asp Lys Lys Gln Ser Asn Arg Ser Gly Gly 10 15 20 tac cgg tct tca gtt cgt ggc tac aag cca gga tca tcc cgc cca aac 211 Tyr Arg Ser Ser Val Arg Gly Tyr Lys Pro Gly Ser Ser Arg Pro Asn 25 30 35 aca cgc cag cag cct cag aag aag gat gag att ctt ctc tcc aac gct 259 Thr Arg Gln Gln Pro Gln Lys Lys Asp Glu Ile Leu Leu Ser Asn Ala 40 45 50 aag cct gcc aag aag caa aac gta aaa tcc gac gac gat tgg tcg atg 307 Lys Pro Ala Lys Lys Gln Asn Val Lys Ser Asp Asp Asp Trp Ser Met 55 60 65 ggt ttc tta aac cgc aat gac tct gac gga gtt cgc ctg cag aag gtg 355 Gly Phe Leu Asn Arg Asn Asp Ser Asp Gly Val Arg Leu Gln Lys Val 70 75 80 85 ctt gcc caa gca ggt gtg gca tca cgt cga cac gca gaa atc ctg att 403 Leu Ala Gln Ala Gly Val Ala Ser Arg Arg His Ala Glu Ile Leu Ile 90 95 100 gat cag ggc cgt gtg gag gtc aac gat cgt atc gtg acc acc cag ggc 451 Asp Gln Gly Arg Val Glu Val Asn Asp Arg Ile Val Thr Thr Gln Gly 105 110 115 gtg cgc gtg gat cca aac aac gat gtc atc cgt gtt gac ggc gtc cgc 499 Val Arg Val Asp Pro Asn Asn Asp Val Ile Arg Val Asp Gly Val Arg 120 125 130 atc cac atc aac gag gac ctc gag tac ttc gtg ctc aac aag cct cgt 547 Ile His Ile Asn Glu Asp Leu Glu Tyr Phe Val Leu Asn Lys Pro Arg 135 140 145 ggc atg cac tcc acc atg agc gat gaa ctt ggt cgc cca tgc gtg ggt 595 Gly Met His Ser Thr Met Ser Asp Glu Leu Gly Arg Pro Cys Val Gly 150 155 160 165 gat ctg gtc agt gag aag act gca tct gga cag cgt ctg ttc cac gtc 643 Asp Leu Val Ser Glu Lys Thr Ala Ser Gly Gln Arg Leu Phe His Val 170 175 180 ggt cgc ctc gac gcg gac acc gaa ggt ttg ctg ctg ctc acc aac gat 691 Gly Arg Leu Asp Ala Asp Thr Glu Gly Leu Leu Leu Leu Thr Asn Asp 185 190 195 ggt gag ttg gct aac cgc ctc atg cac cct aag tac gaa gtg tcc aag 739 Gly Glu Leu Ala Asn Arg Leu Met His Pro Lys Tyr Glu Val Ser Lys 200 205 210 act tac ctt gct acc gtt cgc ggt gaa gca acc aat aag cta gtc agc 787 Thr Tyr Leu Ala Thr Val Arg Gly Glu Ala Thr Asn Lys Leu Val Ser 215 220 225 gct ctt cgt gat ggc gtg gag ttg gaa gat ggc cct gcc aag gct gac 835 Ala Leu Arg Asp Gly Val Glu Leu Glu Asp Gly Pro Ala Lys Ala Asp 230 235 240 245 ttt gcg cag att atc gac gta ttc cag ggc aag tcc ttg ttg cgc atc 883 Phe Ala Gln Ile Ile Asp Val Phe Gln Gly Lys Ser Leu Leu Arg Ile 250 255 260 gaa atc cac gaa ggc cgc aag cac att gtg cga cgc ctc ttc gat gag 931 Glu Ile His Glu Gly Arg Lys His Ile Val Arg Arg Leu Phe Asp Glu 265 270 275 ctc ggt ttc cca gtc gag cgc ctc gtg cgc acc aag ctg cac acc gtt 979 Leu Gly Phe Pro Val Glu Arg Leu Val Arg Thr Lys Leu His Thr Val 280 285 290 cag ctt ggt gat cag aag cca ggt tcc ctt cgt gca ctg aac tcc tct 1027 Gln Leu Gly Asp Gln Lys Pro Gly Ser Leu Arg Ala Leu Asn Ser Ser 295 300 305 gag ctg acc agc tta tac aag gtg gtc caa ctg tgacggaaat ttccaacatg 1080 Glu Leu Thr Ser Leu Tyr Lys Val Val Gln Leu 310 315 320 cct 1083 <210> 1116 <211> 320 <212> PRT <213> Corynebacterium glutamicum <400> 1116 Val Thr Pro Pro Ala Arg Arg Asp Gly Thr Pro Asp Lys Lys Gln Ser 1 5 10 15 Asn Arg Ser Gly Gly Tyr Arg Ser Ser Val Arg Gly Tyr Lys Pro Gly 20 25 30 Ser Ser Arg Pro Asn Thr Arg Gln Gln Pro Gln Lys Lys Asp Glu Ile 35 40 45 Leu Leu Ser Asn Ala Lys Pro Ala Lys Lys Gln Asn Val Lys Ser Asp 50 55 60 Asp Asp Trp Ser Met Gly Phe Leu Asn Arg Asn Asp Ser Asp Gly Val 65 70 75 80 Arg Leu Gln Lys Val Leu Ala Gln Ala Gly Val Ala Ser Arg Arg His 85 90 95 Ala Glu Ile Leu Ile Asp Gln Gly Arg Val Glu Val Asn Asp Arg Ile 100 105 110 Val Thr Thr Gln Gly Val Arg Val Asp Pro Asn Asn Asp Val Ile Arg 115 120 125 Val Asp Gly Val Arg Ile His Ile Asn Glu Asp Leu Glu Tyr Phe Val 130 135 140 Leu Asn Lys Pro Arg Gly Met His Ser Thr Met Ser Asp Glu Leu Gly 145 150 155 160 Arg Pro Cys Val Gly Asp Leu Val Ser Glu Lys Thr Ala Ser Gly Gln 165 170 175 Arg Leu Phe His Val Gly Arg Leu Asp Ala Asp Thr Glu Gly Leu Leu 180 185 190 Leu Leu Thr Asn Asp Gly Glu Leu Ala Asn Arg Leu Met His Pro Lys 195 200 205 Tyr Glu Val Ser Lys Thr Tyr Leu Ala Thr Val Arg Gly Glu Ala Thr 210 215 220 Asn Lys Leu Val Ser Ala Leu Arg Asp Gly Val Glu Leu Glu Asp Gly 225 230 235 240 Pro Ala Lys Ala Asp Phe Ala Gln Ile Ile Asp Val Phe Gln Gly Lys 245 250 255 Ser Leu Leu Arg Ile Glu Ile His Glu Gly Arg Lys His Ile Val Arg 260 265 270 Arg Leu Phe Asp Glu Leu Gly Phe Pro Val Glu Arg Leu Val Arg Thr 275 280 285 Lys Leu His Thr Val Gln Leu Gly Asp Gln Lys Pro Gly Ser Leu Arg 290 295 300 Ala Leu Asn Ser Ser Glu Leu Thr Ser Leu Tyr Lys Val Val Gln Leu 305 310 315 320 <210> 1117 <211> 978 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(955) <223> RXA01894 <400> 1117 agaatttttt cgaaaatgct ggcaccatca acagtgacat tgttagaaac ttcaaggaga 60 acccatgaat gaaccggagc aacatcaccg gtccatgagg atg ccc aaa ccc aaa 115 Met Pro Lys Pro Lys 1 5 aat aat gcg ggt cga gat ctc aaa gct gcc att gct gtg ggg atc gga 163 Asn Asn Ala Gly Arg Asp Leu Lys Ala Ala Ile Ala Val Gly Ile Gly 10 15 20 ctg ggg gtc ctg gtt ctt ttg ggg att gtc cta agc cca tgg ggt tgg 211 Leu Gly Val Leu Val Leu Leu Gly Ile Val Leu Ser Pro Trp Gly Trp 25 30 35 tac atc ctc gtt gca ggt ttt atg gct gca gca aca tgg gaa gtt ggt 259 Tyr Ile Leu Val Ala Gly Phe Met Ala Ala Ala Thr Trp Glu Val Gly 40 45 50 agc aga ctt aaa gaa ggc ggc tat cat ttg cca ctg ccg att atg atc 307 Ser Arg Leu Lys Glu Gly Gly Tyr His Leu Pro Leu Pro Ile Met Ile 55 60 65 atc ggc ggt cag gca atc atc tgg ctg tca tgg cca ttt ggc acg atg 355 Ile Gly Gly Gln Ala Ile Ile Trp Leu Ser Trp Pro Phe Gly Thr Met 70 75 80 85 ggc att ttg gcg tct ttt gtg gcc act gtg ttg gtg ctg atg tat ttc 403 Gly Ile Leu Ala Ser Phe Val Ala Thr Val Leu Val Leu Met Tyr Phe 90 95 100 cga att ttc tac aat ggc acg gaa aaa gaa gcc cgc aac tat ttg agg 451 Arg Ile Phe Tyr Asn Gly Thr Glu Lys Glu Ala Arg Asn Tyr Leu Arg 105 110 115 gac acc tct gtg ggc atc ttc gtg ctc acc tgg att cca ttg ttc gga 499 Asp Thr Ser Val Gly Ile Phe Val Leu Thr Trp Ile Pro Leu Phe Gly 120 125 130 agc ttc gct gcg atg ctg tcg ctg atg caa aac aat tcc atc ccg ggt 547 Ser Phe Ala Ala Met Leu Ser Leu Met Gln Asn Asn Ser Ile Pro Gly 135 140 145 aca tat ttc att ttg acg ttc atg ctg tgt gtg atc gca tcg gat gtg 595 Thr Tyr Phe Ile Leu Thr Phe Met Leu Cys Val Ile Ala Ser Asp Val 150 155 160 165 ggc ggg tat atc gcg ggt gtg ttc ttt gga tcg cac cca atg gcg ccg 643 Gly Gly Tyr Ile Ala Gly Val Phe Phe Gly Ser His Pro Met Ala Pro 170 175 180 ttg gtg agt ccg aag aag tct tgg gaa ggc ttt gcc ggc tcc att gtc 691 Leu Val Ser Pro Lys Lys Ser Trp Glu Gly Phe Ala Gly Ser Ile Val 185 190 195 tta gga tcg gtc act ggt gca ctc agt gtt cac ttc ctg ctc gat cac 739 Leu Gly Ser Val Thr Gly Ala Leu Ser Val His Phe Leu Leu Asp His 200 205 210 cac tgg tgg atg ggt gtg atc ttg ggt tgt gcc cta gtt gtg tgc gcc 787 His Trp Trp Met Gly Val Ile Leu Gly Cys Ala Leu Val Val Cys Ala 215 220 225 acg ttg ggt gac ttg gtt gag tcg cag ttc aaa cgc gat ttg ggc atc 835 Thr Leu Gly Asp Leu Val Glu Ser Gln Phe Lys Arg Asp Leu Gly Ile 230 235 240 245 aag gat atg tcg aac ctt ctt cca ggc cac ggc gga ttg atg gac cgt 883 Lys Asp Met Ser Asn Leu Leu Pro Gly His Gly Gly Leu Met Asp Arg 250 255 260 ttg gat ggc atg ctc ccg gcc gcg atg gtg acg tgg ttg atc ctg agt 931 Leu Asp Gly Met Leu Pro Ala Ala Met Val Thr Trp Leu Ile Leu Ser 265 270 275 gtg atc agc agc tcg tat ccg tcg taaagcttgg gccagcttta agt 978 Val Ile Ser Ser Ser Tyr Pro Ser 280 285 <210> 1118 <211> 285 <212> PRT <213> Corynebacterium glutamicum <400> 1118 Met Pro Lys Pro Lys Asn Asn Ala Gly Arg Asp Leu Lys Ala Ala Ile 1 5 10 15 Ala Val Gly Ile Gly Leu Gly Val Leu Val Leu Leu Gly Ile Val Leu 20 25 30 Ser Pro Trp Gly Trp Tyr Ile Leu Val Ala Gly Phe Met Ala Ala Ala 35 40 45 Thr Trp Glu Val Gly Ser Arg Leu Lys Glu Gly Gly Tyr His Leu Pro 50 55 60 Leu Pro Ile Met Ile Ile Gly Gly Gln Ala Ile Ile Trp Leu Ser Trp 65 70 75 80 Pro Phe Gly Thr Met Gly Ile Leu Ala Ser Phe Val Ala Thr Val Leu 85 90 95 Val Leu Met Tyr Phe Arg Ile Phe Tyr Asn Gly Thr Glu Lys Glu Ala 100 105 110 Arg Asn Tyr Leu Arg Asp Thr Ser Val Gly Ile Phe Val Leu Thr Trp 115 120 125 Ile Pro Leu Phe Gly Ser Phe Ala Ala Met Leu Ser Leu Met Gln Asn 130 135 140 Asn Ser Ile Pro Gly Thr Tyr Phe Ile Leu Thr Phe Met Leu Cys Val 145 150 155 160 Ile Ala Ser Asp Val Gly Gly Tyr Ile Ala Gly Val Phe Phe Gly Ser 165 170 175 His Pro Met Ala Pro Leu Val Ser Pro Lys Lys Ser Trp Glu Gly Phe 180 185 190 Ala Gly Ser Ile Val Leu Gly Ser Val Thr Gly Ala Leu Ser Val His 195 200 205 Phe Leu Leu Asp His His Trp Trp Met Gly Val Ile Leu Gly Cys Ala 210 215 220 Leu Val Val Cys Ala Thr Leu Gly Asp Leu Val Glu Ser Gln Phe Lys 225 230 235 240 Arg Asp Leu Gly Ile Lys Asp Met Ser Asn Leu Leu Pro Gly His Gly 245 250 255 Gly Leu Met Asp Arg Leu Asp Gly Met Leu Pro Ala Ala Met Val Thr 260 265 270 Trp Leu Ile Leu Ser Val Ile Ser Ser Ser Tyr Pro Ser 275 280 285 <210> 1119 <211> 879 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(856) <223> RXA02536 <400> 1119 aagaagtgat cacgcgaacc tgtgtataac ttgcctcaaa gcgcctaggc tgtggattat 60 gcgtattgcc ttgcttcaga tctcgacgaa ttccgataag atg gac aac ttc gcc 115 Met Asp Asn Phe Ala 1 5 ctg ctg cgt gat gct gct gaa aaa gct gcg gaa cag ggg gct cgg gtg 163 Leu Leu Arg Asp Ala Ala Glu Lys Ala Ala Glu Gln Gly Ala Arg Val 10 15 20 ttg gtg ttt ccg gag gcg act tcg caa agc ttt ggt acg gga agg ctt 211 Leu Val Phe Pro Glu Ala Thr Ser Gln Ser Phe Gly Thr Gly Arg Leu 25 30 35 gat act cag gcg gag gag ctc gat ggc gaa ttc tcc acc gcg gta cga 259 Asp Thr Gln Ala Glu Glu Leu Asp Gly Glu Phe Ser Thr Ala Val Arg 40 45 50 aaa tta gcc gat gag ctg gac gtt gtc atc gtt gcg ggc atg ttc acc 307 Lys Leu Ala Asp Glu Leu Asp Val Val Ile Val Ala Gly Met Phe Thr 55 60 65 cct gct gac acc gtg cag cgc ggt gaa aaa acg atc tcg cgc gtc aac 355 Pro Ala Asp Thr Val Gln Arg Gly Glu Lys Thr Ile Ser Arg Val Asn 70 75 80 85 aac acc gtg ctg att agt ggc gct gga ttg cat cag gga tac aac aaa 403 Asn Thr Val Leu Ile Ser Gly Ala Gly Leu His Gln Gly Tyr Asn Lys 90 95 100 att cac aca tat gac gcg ttc ggt tat agg gaa tcc gac act gtg aaa 451 Ile His Thr Tyr Asp Ala Phe Gly Tyr Arg Glu Ser Asp Thr Val Lys 105 110 115 ccg ggc gat gag ctg gtt gta ttc gag gtc gac gat att aaa ttt ggt 499 Pro Gly Asp Glu Leu Val Val Phe Glu Val Asp Asp Ile Lys Phe Gly 120 125 130 gtg gcg aca tgc tac gat att cga ttc cca gaa cag ttc aaa gac ctc 547 Val Ala Thr Cys Tyr Asp Ile Arg Phe Pro Glu Gln Phe Lys Asp Leu 135 140 145 gcc cgc aac ggt gca cag ata att gtg gtt ccc acg tcg tgg caa gac 595 Ala Arg Asn Gly Ala Gln Ile Ile Val Val Pro Thr Ser Trp Gln Asp 150 155 160 165 ggt cct gga aaa tta gaa caa tgg gaa gtc ctc cct cgc gcg cgt gca 643 Gly Pro Gly Lys Leu Glu Gln Trp Glu Val Leu Pro Arg Ala Arg Ala 170 175 180 ctg gat tcc acc tgc tgg atc gta gcg tgt ggg caa gcg cga ctt cca 691 Leu Asp Ser Thr Cys Trp Ile Val Ala Cys Gly Gln Ala Arg Leu Pro 185 190 195 gaa gaa tta cgc gat gaa cga aaa ggc cct acg ggg att ggt cat tcc 739 Glu Glu Leu Arg Asp Glu Arg Lys Gly Pro Thr Gly Ile Gly His Ser 200 205 210 atg gtg aca aac cca cac ggt gaa gta att gct agc gcg ggt tat gag 787 Met Val Thr Asn Pro His Gly Glu Val Ile Ala Ser Ala Gly Tyr Glu 215 220 225 cca gaa atg ttg atc gcg gat att gat gtc agc ggt ttg gcc aaa att 835 Pro Glu Met Leu Ile Ala Asp Ile Asp Val Ser Gly Leu Ala Lys Ile 230 235 240 245 cgg gag gca ttg cct gtt ctt taaccactgt ctaaggaatc act 879 Arg Glu Ala Leu Pro Val Leu 250 <210> 1120 <211> 252 <212> PRT <213> Corynebacterium glutamicum <400> 1120 Met Asp Asn Phe Ala Leu Leu Arg Asp Ala Ala Glu Lys Ala Ala Glu 1 5 10 15 Gln Gly Ala Arg Val Leu Val Phe Pro Glu Ala Thr Ser Gln Ser Phe 20 25 30 Gly Thr Gly Arg Leu Asp Thr Gln Ala Glu Glu Leu Asp Gly Glu Phe 35 40 45 Ser Thr Ala Val Arg Lys Leu Ala Asp Glu Leu Asp Val Val Ile Val 50 55 60 Ala Gly Met Phe Thr Pro Ala Asp Thr Val Gln Arg Gly Glu Lys Thr 65 70 75 80 Ile Ser Arg Val Asn Asn Thr Val Leu Ile Ser Gly Ala Gly Leu His 85 90 95 Gln Gly Tyr Asn Lys Ile His Thr Tyr Asp Ala Phe Gly Tyr Arg Glu 100 105 110 Ser Asp Thr Val Lys Pro Gly Asp Glu Leu Val Val Phe Glu Val Asp 115 120 125 Asp Ile Lys Phe Gly Val Ala Thr Cys Tyr Asp Ile Arg Phe Pro Glu 130 135 140 Gln Phe Lys Asp Leu Ala Arg Asn Gly Ala Gln Ile Ile Val Val Pro 145 150 155 160 Thr Ser Trp Gln Asp Gly Pro Gly Lys Leu Glu Gln Trp Glu Val Leu 165 170 175 Pro Arg Ala Arg Ala Leu Asp Ser Thr Cys Trp Ile Val Ala Cys Gly 180 185 190 Gln Ala Arg Leu Pro Glu Glu Leu Arg Asp Glu Arg Lys Gly Pro Thr 195 200 205 Gly Ile Gly His Ser Met Val Thr Asn Pro His Gly Glu Val Ile Ala 210 215 220 Ser Ala Gly Tyr Glu Pro Glu Met Leu Ile Ala Asp Ile Asp Val Ser 225 230 235 240 Gly Leu Ala Lys Ile Arg Glu Ala Leu Pro Val Leu 245 250 <210> 1121 <211> 1528 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1528) <223> RXN01209 <400> 1121 cagattgcag cacagaaggc atcggcgcca ggcagctttg cggtggcgtt tattgatgcg 60 ctttatgacg tggatgccca ggctgtggcc tcgttggttg atg tgc gag agg cct 115 Met Cys Glu Arg Pro 1 5 gaa aag tac gtg act gat ttt tct ttg tat ctg gtc acc gat ccc gtt 163 Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu Val Thr Asp Pro Val 10 15 20 ttg ggt ggc ggg cca aaa aaa gta gct gga att gtt gac agc gca att 211 Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile Val Asp Ser Ala Ile 25 30 35 tcc ggc gga gtt tct gtg gtg cag ctg cgc gat aag aac tca ggc gtg 259 Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp Lys Asn Ser Gly Val 40 45 50 gaa gat gtt cgt gcg gca gca aag gag ctg aaa gaa ctc tgc gat gct 307 Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys Glu Leu Cys Asp Ala 55 60 65 cgc ggg gtg gcg ctt gtt gtc aac gat tac tta gat atc gcc gtt gag 355 Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu Asp Ile Ala Val Glu 70 75 80 85 ctg ggt ctt cac ctg cac att ggt caa ggc gat aca cct tat acg caa 403 Leu Gly Leu His Leu His Ile Gly Gln Gly Asp Thr Pro Tyr Thr Gln 90 95 100 gca cgg gag ctg ctt cca gct cat ctt gaa ttg ggt ttg agc att gaa 451 Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu Gly Leu Ser Ile Glu 105 110 115 aac ctg gat caa ttg cat gct gtg atc gcg cag tgc gcc gag act ggt 499 Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln Cys Ala Glu Thr Gly 120 125 130 gtg gca ttg ccc gat gtg att ggc att ggt ccg gtg gcc tct act gcg 547 Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro Val Ala Ser Thr Ala 135 140 145 acc aaa cca gat gcg gca ccc gca ttg ggt gtg gag ggc atc gct gag 595 Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val Glu Gly Ile Ala Glu 150 155 160 165 atc gcc gct gta gct caa gac cac ggc atc gca tca gta gct att gga 643 Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala Ser Val Ala Ile Gly 170 175 180 ggc gtt ggt cta cgc aac gcg gcc gaa ctc gct gct acg ccc atc gac 691 Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala Ala Thr Pro Ile Asp 185 190 195 ggt ctg tgc gtg gtc tct gaa atc atg acc gcc gcc aat cca gca gct 739 Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala Ala Asn Pro Ala Ala 200 205 210 gcg gca act cgc ctg cgg act gct ttt caa cct act ttc tcg cct gaa 787 Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro Thr Phe Ser Pro Glu 215 220 225 act caa act gaa ctc tct caa aca gaa ctc caa gga gcc ttc gtg aat 835 Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln Gly Ala Phe Val Asn 230 235 240 245 tcg cct tct gcc cca cgt gtg ttg tct att gca ggc act gat ccc aca 883 Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala Gly Thr Asp Pro Thr 250 255 260 ggt ggt gca ggt att cag gct gat ctg aag tcc att gca gca ggt ggc 931 Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser Ile Ala Ala Gly Gly 265 270 275 ggc tac ggc atg tgc gtt gtg acc tcg ctg gtc gcg caa aac acc cac 979 Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val Ala Gln Asn Thr His 280 285 290 ggc gtc aac acg atc cac acc cca ccc ttg acc ttt ttg gaa gaa cag 1027 Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr Phe Leu Glu Glu Gln 295 300 305 ctg gaa gcg gtc ttt tcc gat gtc acc gtc gat gcc atc aag ctc ggc 1075 Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp Ala Ile Lys Leu Gly 310 315 320 325 atg ttg ggc tct gcc gac acc gtc gat ctg gtg gct tca tgg ctt ggt 1123 Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val Ala Ser Trp Leu Gly 330 335 340 tcc cac gag cac ggt ccc gtg gtg ctt gat ccc gtc atg atc gcc acc 1171 Ser His Glu His Gly Pro Val Val Leu Asp Pro Val Met Ile Ala Thr 345 350 355 agc ggt gat cgc cta ctg gat gcg agc gct gaa gaa tcg ctg cgc cgc 1219 Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu Glu Ser Leu Arg Arg 360 365 370 ctg gcc gtg cac gtc gat gtg gtc acc ccg aat atc ccc gaa ctt gcc 1267 Leu Ala Val His Val Asp Val Val Thr Pro Asn Ile Pro Glu Leu Ala 375 380 385 gtg ttg tgc gac agt gct cct gcc atc acc atg gat gag gcc att gct 1315 Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met Asp Glu Ala Ile Ala 390 395 400 405 cag gct cag gga ttt gcg cgg act cat gac acc atc gtc att gtc aag 1363 Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr Ile Val Ile Val Lys 410 415 420 ggt gga cat ctg act ggc gcg ctt gct gat aac gct gtc gtg cgc ccc 1411 Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn Ala Val Val Arg Pro 425 430 435 gac ggc tcg gtg ttc cag gtg gaa aac ctg cgt gtc aac acc acc aac 1459 Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg Val Asn Thr Thr Asn 440 445 450 tcc cat ggc aca ggc tgt tcg ctc tct gcg tca ctt gcc acc aag atc 1507 Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser Leu Ala Thr Lys Ile 455 460 465 gcc gcc ggc gaa agc gtg gaa 1528 Ala Ala Gly Glu Ser Val Glu 470 475 <210> 1122 <211> 476 <212> PRT <213> Corynebacterium glutamicum <400> 1122 Met Cys Glu Arg Pro Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu 1 5 10 15 Val Thr Asp Pro Val Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile 20 25 30 Val Asp Ser Ala Ile Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp 35 40 45 Lys Asn Ser Gly Val Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys 50 55 60 Glu Leu Cys Asp Ala Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu 65 70 75 80 Asp Ile Ala Val Glu Leu Gly Leu His Leu His Ile Gly Gln Gly Asp 85 90 95 Thr Pro Tyr Thr Gln Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu 100 105 110 Gly Leu Ser Ile Glu Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln 115 120 125 Cys Ala Glu Thr Gly Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro 130 135 140 Val Ala Ser Thr Ala Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val 145 150 155 160 Glu Gly Ile Ala Glu Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala 165 170 175 Ser Val Ala Ile Gly Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala 180 185 190 Ala Thr Pro Ile Asp Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala 195 200 205 Ala Asn Pro Ala Ala Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro 210 215 220 Thr Phe Ser Pro Glu Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln 225 230 235 240 Gly Ala Phe Val Asn Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala 245 250 255 Gly Thr Asp Pro Thr Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser 260 265 270 Ile Ala Ala Gly Gly Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val 275 280 285 Ala Gln Asn Thr His Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr 290 295 300 Phe Leu Glu Glu Gln Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp 305 310 315 320 Ala Ile Lys Leu Gly Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val 325 330 335 Ala Ser Trp Leu Gly Ser His Glu His Gly Pro Val Val Leu Asp Pro 340 345 350 Val Met Ile Ala Thr Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu 355 360 365 Glu Ser Leu Arg Arg Leu Ala Val His Val Asp Val Val Thr Pro Asn 370 375 380 Ile Pro Glu Leu Ala Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met 385 390 395 400 Asp Glu Ala Ile Ala Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr 405 410 415 Ile Val Ile Val Lys Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn 420 425 430 Ala Val Val Arg Pro Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg 435 440 445 Val Asn Thr Thr Asn Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser 450 455 460 Leu Ala Thr Lys Ile Ala Ala Gly Glu Ser Val Glu 465 470 475 <210> 1123 <211> 1528 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1528) <223> FRXA01209 <400> 1123 cagattgcag cacagaaggc atcggcgcca ggcagctttg cggtggcgtt tattgatgcg 60 ctttatgacg tggatgccca ggctgtggcc tcgttggttg atg tgc gag agg cct 115 Met Cys Glu Arg Pro 1 5 gaa aag tac gtg act gat ttt tct ttg tat ctg gtc acc gat ccc gtt 163 Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu Val Thr Asp Pro Val 10 15 20 ttg ggt ggc ggg cca aaa aaa gta gct gga att gtt gac agc gca att 211 Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile Val Asp Ser Ala Ile 25 30 35 tcc ggc gga gtt tct gtg gtg cag ctg cgc gat aag aac tca ggc gtg 259 Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp Lys Asn Ser Gly Val 40 45 50 gaa gat gtt cgt gcg gca gca aag gag ctg aaa gaa ctc tgc gat gct 307 Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys Glu Leu Cys Asp Ala 55 60 65 cgc ggg gtg gcg ctt gtt gtc aac gat tac tta gat atc gcc gtt gag 355 Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu Asp Ile Ala Val Glu 70 75 80 85 ctg ggt ctt cac ctg cac att ggt caa ggc gat aca cct tat acg caa 403 Leu Gly Leu His Leu His Ile Gly Gln Gly Asp Thr Pro Tyr Thr Gln 90 95 100 gca cgg gag ctg ctt cca gct cat ctt gaa ttg ggt ttg agc att gaa 451 Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu Gly Leu Ser Ile Glu 105 110 115 aac ctg gat caa ttg cat gct gtg atc gcg cag tgc gcc gag act ggt 499 Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln Cys Ala Glu Thr Gly 120 125 130 gtg gca ttg ccc gat gtg att ggc att ggt ccg gtg gcc tct act gcg 547 Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro Val Ala Ser Thr Ala 135 140 145 acc aaa cca gat gcg gca ccc gca ttg ggt gtg gag ggc atc gct gag 595 Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val Glu Gly Ile Ala Glu 150 155 160 165 atc gcc gct gta gct caa gac cac ggc atc gca tca gta gct att gga 643 Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala Ser Val Ala Ile Gly 170 175 180 ggc gtt ggt cta cgc aac gcg gcc gaa ctc gct gct acg ccc atc gac 691 Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala Ala Thr Pro Ile Asp 185 190 195 ggt ctg tgc gtg gtc tct gaa atc atg acc gcc gcc aat cca gca gct 739 Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala Ala Asn Pro Ala Ala 200 205 210 gcg gca act cgc ctg cgg act gct ttt caa cct act ttc tcg cct gaa 787 Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro Thr Phe Ser Pro Glu 215 220 225 act caa act gaa ctc tct caa aca gaa ctc caa gga gcc ttc gtg aat 835 Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln Gly Ala Phe Val Asn 230 235 240 245 tcg cct tct gcc cca cgt gtg ttg tct att gca ggc act gat ccc aca 883 Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala Gly Thr Asp Pro Thr 250 255 260 ggt ggt gca ggt att cag gct gat ctg aag tcc att gca gca ggt ggc 931 Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser Ile Ala Ala Gly Gly 265 270 275 ggc tac ggc atg tgc gtt gtg acc tcg ctg gtc gcg caa aac acc cac 979 Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val Ala Gln Asn Thr His 280 285 290 ggc gtc aac acg atc cac acc cca ccc ttg acc ttt ttg gaa gaa cag 1027 Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr Phe Leu Glu Glu Gln 295 300 305 ctg gaa gcg gtc ttt tcc gat gtc acc gtc gat gcc atc aag ctc ggc 1075 Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp Ala Ile Lys Leu Gly 310 315 320 325 atg ttg ggc tct gcc gac acc gtc gat ctg gtg gct tca tgg ctt ggt 1123 Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val Ala Ser Trp Leu Gly 330 335 340 tcc cac gag cac ggt ccc gtg gtg ctt gat ccc gtc atg atc gcc acc 1171 Ser His Glu His Gly Pro Val Val Leu Asp Pro Val Met Ile Ala Thr 345 350 355 agc ggt gat cgc cta ctg gat gcg agc gct gaa gaa tcg ctg cgc cgc 1219 Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu Glu Ser Leu Arg Arg 360 365 370 ctg gcc gtg cac gtc gat gtg gtc acc ccg aat atc ccc gaa ctt gcc 1267 Leu Ala Val His Val Asp Val Val Thr Pro Asn Ile Pro Glu Leu Ala 375 380 385 gtg ttg tgc gac agt gct cct gcc atc acc atg gat gag gcc att gct 1315 Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met Asp Glu Ala Ile Ala 390 395 400 405 cag gct cag gga ttt gcg cgg act cat gac acc atc gtc att gtc aag 1363 Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr Ile Val Ile Val Lys 410 415 420 ggt gga cat ctg act ggc gcg ctt gct gat aac gct gtc gtg cgc ccc 1411 Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn Ala Val Val Arg Pro 425 430 435 gac ggc tcg gtg ttc cag gtg gaa aac ctg cgt gtc aac acc acc aac 1459 Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg Val Asn Thr Thr Asn 440 445 450 tcc cat ggc aca ggc tgt tcg ctc tct gcg tca ctt gcc acc aag atc 1507 Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser Leu Ala Thr Lys Ile 455 460 465 gcc gcc ggc gaa agc gtg gaa 1528 Ala Ala Gly Glu Ser Val Glu 470 475 <210> 1124 <211> 476 <212> PRT <213> Corynebacterium glutamicum <400> 1124 Met Cys Glu Arg Pro Glu Lys Tyr Val Thr Asp Phe Ser Leu Tyr Leu 1 5 10 15 Val Thr Asp Pro Val Leu Gly Gly Gly Pro Lys Lys Val Ala Gly Ile 20 25 30 Val Asp Ser Ala Ile Ser Gly Gly Val Ser Val Val Gln Leu Arg Asp 35 40 45 Lys Asn Ser Gly Val Glu Asp Val Arg Ala Ala Ala Lys Glu Leu Lys 50 55 60 Glu Leu Cys Asp Ala Arg Gly Val Ala Leu Val Val Asn Asp Tyr Leu 65 70 75 80 Asp Ile Ala Val Glu Leu Gly Leu His Leu His Ile Gly Gln Gly Asp 85 90 95 Thr Pro Tyr Thr Gln Ala Arg Glu Leu Leu Pro Ala His Leu Glu Leu 100 105 110 Gly Leu Ser Ile Glu Asn Leu Asp Gln Leu His Ala Val Ile Ala Gln 115 120 125 Cys Ala Glu Thr Gly Val Ala Leu Pro Asp Val Ile Gly Ile Gly Pro 130 135 140 Val Ala Ser Thr Ala Thr Lys Pro Asp Ala Ala Pro Ala Leu Gly Val 145 150 155 160 Glu Gly Ile Ala Glu Ile Ala Ala Val Ala Gln Asp His Gly Ile Ala 165 170 175 Ser Val Ala Ile Gly Gly Val Gly Leu Arg Asn Ala Ala Glu Leu Ala 180 185 190 Ala Thr Pro Ile Asp Gly Leu Cys Val Val Ser Glu Ile Met Thr Ala 195 200 205 Ala Asn Pro Ala Ala Ala Ala Thr Arg Leu Arg Thr Ala Phe Gln Pro 210 215 220 Thr Phe Ser Pro Glu Thr Gln Thr Glu Leu Ser Gln Thr Glu Leu Gln 225 230 235 240 Gly Ala Phe Val Asn Ser Pro Ser Ala Pro Arg Val Leu Ser Ile Ala 245 250 255 Gly Thr Asp Pro Thr Gly Gly Ala Gly Ile Gln Ala Asp Leu Lys Ser 260 265 270 Ile Ala Ala Gly Gly Gly Tyr Gly Met Cys Val Val Thr Ser Leu Val 275 280 285 Ala Gln Asn Thr His Gly Val Asn Thr Ile His Thr Pro Pro Leu Thr 290 295 300 Phe Leu Glu Glu Gln Leu Glu Ala Val Phe Ser Asp Val Thr Val Asp 305 310 315 320 Ala Ile Lys Leu Gly Met Leu Gly Ser Ala Asp Thr Val Asp Leu Val 325 330 335 Ala Ser Trp Leu Gly Ser His Glu His Gly Pro Val Val Leu Asp Pro 340 345 350 Val Met Ile Ala Thr Ser Gly Asp Arg Leu Leu Asp Ala Ser Ala Glu 355 360 365 Glu Ser Leu Arg Arg Leu Ala Val His Val Asp Val Val Thr Pro Asn 370 375 380 Ile Pro Glu Leu Ala Val Leu Cys Asp Ser Ala Pro Ala Ile Thr Met 385 390 395 400 Asp Glu Ala Ile Ala Gln Ala Gln Gly Phe Ala Arg Thr His Asp Thr 405 410 415 Ile Val Ile Val Lys Gly Gly His Leu Thr Gly Ala Leu Ala Asp Asn 420 425 430 Ala Val Val Arg Pro Asp Gly Ser Val Phe Gln Val Glu Asn Leu Arg 435 440 445 Val Asn Thr Thr Asn Ser His Gly Thr Gly Cys Ser Leu Ser Ala Ser 450 455 460 Leu Ala Thr Lys Ile Ala Ala Gly Glu Ser Val Glu 465 470 475 <210> 1125 <211> 795 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(772) <223> RXN01617 <400> 1125 tcagaagcta ccggcggcgc cggcatccag gttgatttga agaccttcca gcatttaaga 60 tgtttatggc attgggtcca tcacatgctt gggtggcctt ttg atc cta aag aca 115 Leu Ile Leu Lys Thr 1 5 act gga atc acc gtt ttg tcc cgg ttt gat gcg cag gtt atc gct aat 163 Thr Gly Ile Thr Val Leu Ser Arg Phe Asp Ala Gln Val Ile Ala Asn 10 15 20 cag att gag gcc gcc acc gca gcg cac gat ctt gat gtg gtg aag atc 211 Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu Asp Val Val Lys Ile 25 30 35 ggt atg ttg ggt act cct gca acg atc gat act gtg gca acc gct ttg 259 Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr Val Ala Thr Ala Leu 40 45 50 gag gaa aac agc ttc aag cac gtt gtc cta gac ccg gta ctg atc tgc 307 Glu Glu Asn Ser Phe Lys His Val Val Leu Asp Pro Val Leu Ile Cys 55 60 65 aag ggc cag gag ccc ggc gcg gca ctt gat act gac act gcc ctt cgc 355 Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr Asp Thr Ala Leu Arg 70 75 80 85 gcg aag gtg ctg cca cag gca acc gtg gtt act cca aac aac ttc gag 403 Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn Phe Glu 90 95 100 gcc acc acc ctg tct ggc cta gac aag ctg gag acc atc gac gac ctg 451 Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu Thr Ile Asp Asp Leu 105 110 115 aag gaa gca gcc cgc ctc att cat gag caa gga cct cag tac gtc gtt 499 Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly Pro Gln Tyr Val Val 120 125 130 gtt aag ggt ggc atc gac ttc cca ggc gac aac gct gtg gac gta ctt 547 Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn Ala Val Asp Val Leu 135 140 145 ttc gac ggc acc gac tac cac gtg ttc tct gaa cca aag atc ggc gac 595 Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu Pro Lys Ile Gly Asp 150 155 160 165 gag cgc gtc tcc ggc gct ggc tgt acc ttc gca gct gtc atc acc gca 643 Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala Ala Val Ile Thr Ala 170 175 180 gag ctg gcc aag ggc aac tct gcc gtt gat gca gtg acc acc gct aag 691 Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala Val Thr Thr Ala Lys 185 190 195 cgc gta gtc acc cgc gca gtg aag gac gct gtc gca tcc aac gca ccg 739 Arg Val Val Thr Arg Ala Val Lys Asp Ala Val Ala Ser Asn Ala Pro 200 205 210 ttt acc tct gtg tgg ttg gcg gaa gac aac aag tagaaatctt aaacaagctc 792 Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 215 220 cct 795 <210> 1126 <211> 224 <212> PRT <213> Corynebacterium glutamicum <400> 1126 Leu Ile Leu Lys Thr Thr Gly Ile Thr Val Leu Ser Arg Phe Asp Ala 1 5 10 15 Gln Val Ile Ala Asn Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu 20 25 30 Asp Val Val Lys Ile Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr 35 40 45 Val Ala Thr Ala Leu Glu Glu Asn Ser Phe Lys His Val Val Leu Asp 50 55 60 Pro Val Leu Ile Cys Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr 65 70 75 80 Asp Thr Ala Leu Arg Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr 85 90 95 Pro Asn Asn Phe Glu Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu 100 105 110 Thr Ile Asp Asp Leu Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly 115 120 125 Pro Gln Tyr Val Val Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn 130 135 140 Ala Val Asp Val Leu Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu 145 150 155 160 Pro Lys Ile Gly Asp Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala 165 170 175 Ala Val Ile Thr Ala Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala 180 185 190 Val Thr Thr Ala Lys Arg Val Val Thr Arg Ala Val Lys Asp Ala Val 195 200 205 Ala Ser Asn Ala Pro Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 210 215 220 <210> 1127 <211> 638 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(615) <223> FRXA01617 <400> 1127 gct aat cag att gag gcc gcc acc gca gcg cac gat ctt gat gtg gtg 48 Ala Asn Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu Asp Val Val 1 5 10 15 aag atc ggt atg ttg ggt act cct gca acg atc gat act gtg gca acc 96 Lys Ile Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr Val Ala Thr 20 25 30 gct ttg gag gaa aac agc ttc aag cac gtt gtc cta gac ccg gta ctg 144 Ala Leu Glu Glu Asn Ser Phe Lys His Val Val Leu Asp Pro Val Leu 35 40 45 atc tgc aag ggc cag gag ccc ggc gcg gca ctt gat act gac act gcc 192 Ile Cys Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr Asp Thr Ala 50 55 60 ctt cgc gcg aag gtg ctg cca cag gca acc gtg gtt act cca aac aac 240 Leu Arg Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn 65 70 75 80 ttc gag gcc acc acc ctg tct ggc cta gac aag ctg gag acc atc gac 288 Phe Glu Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu Thr Ile Asp 85 90 95 gac ctg aag gaa gca gcc cgc ctc att cat gag caa gga cct cag tac 336 Asp Leu Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly Pro Gln Tyr 100 105 110 gtc gtt gtt aag ggt ggc atc gac ttc cca ggc gac aac gct gtg gac 384 Val Val Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn Ala Val Asp 115 120 125 gta ctt ttc gac ggc acc gac tac cac gtg ttc tct gaa cca aag atc 432 Val Leu Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu Pro Lys Ile 130 135 140 ggc gac gag cgc gtc tcc ggc gct ggc tgt acc ttc gca gct gtc atc 480 Gly Asp Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala Ala Val Ile 145 150 155 160 acc gca gag ctg gcc aag ggc aac tct gcc gtt gat gca gtg acc acc 528 Thr Ala Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala Val Thr Thr 165 170 175 gct aag cgc gta gtc acc cgc gca gtg aag gac gct gtc gca tcc aac 576 Ala Lys Arg Val Val Thr Arg Ala Val Lys Asp Ala Val Ala Ser Asn 180 185 190 gca ccg ttt acc tct gtg tgg ttg gcg gaa gac aac aag tagaaatctt 625 Ala Pro Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 195 200 205 aaacaagctc cct 638 <210> 1128 <211> 205 <212> PRT <213> Corynebacterium glutamicum <400> 1128 Ala Asn Gln Ile Glu Ala Ala Thr Ala Ala His Asp Leu Asp Val Val 1 5 10 15 Lys Ile Gly Met Leu Gly Thr Pro Ala Thr Ile Asp Thr Val Ala Thr 20 25 30 Ala Leu Glu Glu Asn Ser Phe Lys His Val Val Leu Asp Pro Val Leu 35 40 45 Ile Cys Lys Gly Gln Glu Pro Gly Ala Ala Leu Asp Thr Asp Thr Ala 50 55 60 Leu Arg Ala Lys Val Leu Pro Gln Ala Thr Val Val Thr Pro Asn Asn 65 70 75 80 Phe Glu Ala Thr Thr Leu Ser Gly Leu Asp Lys Leu Glu Thr Ile Asp 85 90 95 Asp Leu Lys Glu Ala Ala Arg Leu Ile His Glu Gln Gly Pro Gln Tyr 100 105 110 Val Val Val Lys Gly Gly Ile Asp Phe Pro Gly Asp Asn Ala Val Asp 115 120 125 Val Leu Phe Asp Gly Thr Asp Tyr His Val Phe Ser Glu Pro Lys Ile 130 135 140 Gly Asp Glu Arg Val Ser Gly Ala Gly Cys Thr Phe Ala Ala Val Ile 145 150 155 160 Thr Ala Glu Leu Ala Lys Gly Asn Ser Ala Val Asp Ala Val Thr Thr 165 170 175 Ala Lys Arg Val Val Thr Arg Ala Val Lys Asp Ala Val Ala Ser Asn 180 185 190 Ala Pro Phe Thr Ser Val Trp Leu Ala Glu Asp Asn Lys 195 200 205 <210> 1129 <211> 792 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(769) <223> RXC01600 <400> 1129 tgagtacaaa tctcgtccaa cccatgctca tccactgttt tacggcctgg tgaagaccgc 60 tttggagctg cgtgtccacc cttagatcta caatgtgatc atg gtt tcg aag atg 115 Met Val Ser Lys Met 1 5 cac att ccc ggt acc cat gag ttc acg gtg aca gat act gaa ctg ttg 163 His Ile Pro Gly Thr His Glu Phe Thr Val Thr Asp Thr Glu Leu Leu 10 15 20 tta gag tcc cca att ttg ggc gtt cgt cga gat tca ttg atc atg ccg 211 Leu Glu Ser Pro Ile Leu Gly Val Arg Arg Asp Ser Leu Ile Met Pro 25 30 35 ggt ggt tcc act gcc cgc cgt gaa gtg gtt gaa cac ttt ggg gcg gtc 259 Gly Gly Ser Thr Ala Arg Arg Glu Val Val Glu His Phe Gly Ala Val 40 45 50 gca gtg gtt gcc ttt gat ggt gaa aac att gcg atg gtc aag cag tac 307 Ala Val Val Ala Phe Asp Gly Glu Asn Ile Ala Met Val Lys Gln Tyr 55 60 65 cgt cgc agc gtg ggg gat tcc ttg tgg gag ctg cct gca ggt ttg ttg 355 Arg Arg Ser Val Gly Asp Ser Leu Trp Glu Leu Pro Ala Gly Leu Leu 70 75 80 85 gat att gct gat gag gat gaa ctc acg ggc gcg cag cgc gag ctc atg 403 Asp Ile Ala Asp Glu Asp Glu Leu Thr Gly Ala Gln Arg Glu Leu Met 90 95 100 gag gag gct ggt ttg gag gcc agt gag tgg tcc gtg ctc act gat ttg 451 Glu Glu Ala Gly Leu Glu Ala Ser Glu Trp Ser Val Leu Thr Asp Leu 105 110 115 att acc tcg cct ggt ttc tgc gat gaa gcg gtg cgt gtc ttt cta gcc 499 Ile Thr Ser Pro Gly Phe Cys Asp Glu Ala Val Arg Val Phe Leu Ala 120 125 130 cga ggc ctc aca aag gtt gag cgc ccg aag gtt atg ggc gat gaa gaa 547 Arg Gly Leu Thr Lys Val Glu Arg Pro Lys Val Met Gly Asp Glu Glu 135 140 145 gcg gac atg att aac cag tgg gtt ccg cta cat gag gca gtg gga atg 595 Ala Asp Met Ile Asn Gln Trp Val Pro Leu His Glu Ala Val Gly Met 150 155 160 165 gtg ttt agt ggc cag ttg gtt aac tcc att gcc att gcg ggt gtc atg 643 Val Phe Ser Gly Gln Leu Val Asn Ser Ile Ala Ile Ala Gly Val Met 170 175 180 gct gct gat gct gtg att gcg ggt cgt gcg tct gcg cgt gcc gtc acc 691 Ala Ala Asp Ala Val Ile Ala Gly Arg Ala Ser Ala Arg Ala Val Thr 185 190 195 gcg ccg ttt acc tat cgc cct acg gcg ttg gcg cag cgt cga aaa gcg 739 Ala Pro Phe Thr Tyr Arg Pro Thr Ala Leu Ala Gln Arg Arg Lys Ala 200 205 210 cac ggc att gtt cct gac atg aaa aaa cta tgaaggctcg cgttttagcg 789 His Gly Ile Val Pro Asp Met Lys Lys Leu 215 220 aaa 792 <210> 1130 <211> 223 <212> PRT <213> Corynebacterium glutamicum <400> 1130 Met Val Ser Lys Met His Ile Pro Gly Thr His Glu Phe Thr Val Thr 1 5 10 15 Asp Thr Glu Leu Leu Leu Glu Ser Pro Ile Leu Gly Val Arg Arg Asp 20 25 30 Ser Leu Ile Met Pro Gly Gly Ser Thr Ala Arg Arg Glu Val Val Glu 35 40 45 His Phe Gly Ala Val Ala Val Val Ala Phe Asp Gly Glu Asn Ile Ala 50 55 60 Met Val Lys Gln Tyr Arg Arg Ser Val Gly Asp Ser Leu Trp Glu Leu 65 70 75 80 Pro Ala Gly Leu Leu Asp Ile Ala Asp Glu Asp Glu Leu Thr Gly Ala 85 90 95 Gln Arg Glu Leu Met Glu Glu Ala Gly Leu Glu Ala Ser Glu Trp Ser 100 105 110 Val Leu Thr Asp Leu Ile Thr Ser Pro Gly Phe Cys Asp Glu Ala Val 115 120 125 Arg Val Phe Leu Ala Arg Gly Leu Thr Lys Val Glu Arg Pro Lys Val 130 135 140 Met Gly Asp Glu Glu Ala Asp Met Ile Asn Gln Trp Val Pro Leu His 145 150 155 160 Glu Ala Val Gly Met Val Phe Ser Gly Gln Leu Val Asn Ser Ile Ala 165 170 175 Ile Ala Gly Val Met Ala Ala Asp Ala Val Ile Ala Gly Arg Ala Ser 180 185 190 Ala Arg Ala Val Thr Ala Pro Phe Thr Tyr Arg Pro Thr Ala Leu Ala 195 200 205 Gln Arg Arg Lys Ala His Gly Ile Val Pro Asp Met Lys Lys Leu 210 215 220 <210> 1131 <211> 726 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(703) <223> RXC01622 <400> 1131 aaggcgtggg cgtttttgaa ggagcttcgt ttggagcgcg gtcctttgga tcgtgaagtt 60 gccatcgcag agctgaagag ctggtgggaa ggagaaaaca atg agt gat ttt tat 115 Met Ser Asp Phe Tyr 1 5 gcc gac agg ttg ttt aac gcg atg gag cgc aat gag gta gct cca ggc 163 Ala Asp Arg Leu Phe Asn Ala Met Glu Arg Asn Glu Val Ala Pro Gly 10 15 20 atg ttg ttg gtg gct gcg ccc gat atg gcg tcg gag gat ttt gag cgc 211 Met Leu Leu Val Ala Ala Pro Asp Met Ala Ser Glu Asp Phe Glu Arg 25 30 35 agc atc gtg ttg atc atc gag cat tct cct gcc acc act ttt ggt gtg 259 Ser Ile Val Leu Ile Ile Glu His Ser Pro Ala Thr Thr Phe Gly Val 40 45 50 aac att tct tca cgt tcc gat gtt gct gtg gcc aat gtg ttg ccc gag 307 Asn Ile Ser Ser Arg Ser Asp Val Ala Val Ala Asn Val Leu Pro Glu 55 60 65 tgg gtg gac ctc acc tcg aag cca cag gca ctg tac atc ggt ggg ccg 355 Trp Val Asp Leu Thr Ser Lys Pro Gln Ala Leu Tyr Ile Gly Gly Pro 70 75 80 85 ttg agc cag cag gct gtg gtt ggt ttg ggc gtg acc aag ccg ggc gtg 403 Leu Ser Gln Gln Ala Val Val Gly Leu Gly Val Thr Lys Pro Gly Val 90 95 100 gat att gaa aat tcc acc agc ttc aac aag ctc gcc aac cgc ctg gtg 451 Asp Ile Glu Asn Ser Thr Ser Phe Asn Lys Leu Ala Asn Arg Leu Val 105 110 115 cac gtg gat ctg cgt tct gca cct gaa gat gtg gct gat gat ctt gag 499 His Val Asp Leu Arg Ser Ala Pro Glu Asp Val Ala Asp Asp Leu Glu 120 125 130 ggc atg cgc ttt ttt gcg ggc tac gcg gag tgg gct ccg ggc cag ctc 547 Gly Met Arg Phe Phe Ala Gly Tyr Ala Glu Trp Ala Pro Gly Gln Leu 135 140 145 aac gag gaa att gag cag ggt gat tgg ttc gtc aca cct gcg ttg ccg 595 Asn Glu Glu Ile Glu Gln Gly Asp Trp Phe Val Thr Pro Ala Leu Pro 150 155 160 165 tcg gac att atc gcg ccg ggc cgc gtc gat att tgg ggc gac gtg atg 643 Ser Asp Ile Ile Ala Pro Gly Arg Val Asp Ile Trp Gly Asp Val Met 170 175 180 cgt cga caa gca atg cct ttg ccg ttg tat tcc acg ttt ccg tcg gac 691 Arg Arg Gln Ala Met Pro Leu Pro Leu Tyr Ser Thr Phe Pro Ser Asp 185 190 195 cct tca gat aat tagatgagtt ccgaaaattt aaa 726 Pro Ser Asp Asn 200 <210> 1132 <211> 201 <212> PRT <213> Corynebacterium glutamicum <400> 1132 Met Ser Asp Phe Tyr Ala Asp Arg Leu Phe Asn Ala Met Glu Arg Asn 1 5 10 15 Glu Val Ala Pro Gly Met Leu Leu Val Ala Ala Pro Asp Met Ala Ser 20 25 30 Glu Asp Phe Glu Arg Ser Ile Val Leu Ile Ile Glu His Ser Pro Ala 35 40 45 Thr Thr Phe Gly Val Asn Ile Ser Ser Arg Ser Asp Val Ala Val Ala 50 55 60 Asn Val Leu Pro Glu Trp Val Asp Leu Thr Ser Lys Pro Gln Ala Leu 65 70 75 80 Tyr Ile Gly Gly Pro Leu Ser Gln Gln Ala Val Val Gly Leu Gly Val 85 90 95 Thr Lys Pro Gly Val Asp Ile Glu Asn Ser Thr Ser Phe Asn Lys Leu 100 105 110 Ala Asn Arg Leu Val His Val Asp Leu Arg Ser Ala Pro Glu Asp Val 115 120 125 Ala Asp Asp Leu Glu Gly Met Arg Phe Phe Ala Gly Tyr Ala Glu Trp 130 135 140 Ala Pro Gly Gln Leu Asn Glu Glu Ile Glu Gln Gly Asp Trp Phe Val 145 150 155 160 Thr Pro Ala Leu Pro Ser Asp Ile Ile Ala Pro Gly Arg Val Asp Ile 165 170 175 Trp Gly Asp Val Met Arg Arg Gln Ala Met Pro Leu Pro Leu Tyr Ser 180 185 190 Thr Phe Pro Ser Asp Pro Ser Asp Asn 195 200 <210> 1133 <211> 1827 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1804) <223> RXC00128 <400> 1133 ccattttccg tttggtcttg cctaaagaac cgcatggaaa ttatcgtgaa gcaccgatcc 60 cgttgatcgc tccagagaca ccgtgggaag gggagcagca gtg agt aaa att tcg 115 Val Ser Lys Ile Ser 1 5 acg aaa ctg aag gcc ctc acc gcg gtg ctg tct gtg acc act ctg gtg 163 Thr Lys Leu Lys Ala Leu Thr Ala Val Leu Ser Val Thr Thr Leu Val 10 15 20 gct ggg tgt tcc acg ctt ccg cag aac acg gat ccg caa gtg ctg cgc 211 Ala Gly Cys Ser Thr Leu Pro Gln Asn Thr Asp Pro Gln Val Leu Arg 25 30 35 tca ttt tcc ggg tcc caa agc aca caa gag ata gca ggg ccg acc ccg 259 Ser Phe Ser Gly Ser Gln Ser Thr Gln Glu Ile Ala Gly Pro Thr Pro 40 45 50 aat caa gat ccg gat ttg ttg atc cgc ggc ttc ttc agc gca ggt gcg 307 Asn Gln Asp Pro Asp Leu Leu Ile Arg Gly Phe Phe Ser Ala Gly Ala 55 60 65 tat ccg act cag cag tat gaa gcg gcg aag gcg tat ctg acg gaa ggg 355 Tyr Pro Thr Gln Gln Tyr Glu Ala Ala Lys Ala Tyr Leu Thr Glu Gly 70 75 80 85 acg cgc agc acg tgg aat ccg gct gcg tcg act cgt att ttg gat cgc 403 Thr Arg Ser Thr Trp Asn Pro Ala Ala Ser Thr Arg Ile Leu Asp Arg 90 95 100 att gat ctg aac act ctg cca ggt tcg acg aat gcg gaa cga acg att 451 Ile Asp Leu Asn Thr Leu Pro Gly Ser Thr Asn Ala Glu Arg Thr Ile 105 110 115 gcg atc cgt gga acg cag gtc gga acg ttg ctc agc ggt ggc gtg tat 499 Ala Ile Arg Gly Thr Gln Val Gly Thr Leu Leu Ser Gly Gly Val Tyr 120 125 130 cag ccg gag aat gcg gag ttt gaa gct gag atc acg atg cgt cgg gaa 547 Gln Pro Glu Asn Ala Glu Phe Glu Ala Glu Ile Thr Met Arg Arg Glu 135 140 145 gat ggg gag tgg cgt atc gat gct ttg ccg gac ggg att tta tta gag 595 Asp Gly Glu Trp Arg Ile Asp Ala Leu Pro Asp Gly Ile Leu Leu Glu 150 155 160 165 aga aac gat ctg cgg aac cat tac act ccg cac gat gtg tat ttc ttt 643 Arg Asn Asp Leu Arg Asn His Tyr Thr Pro His Asp Val Tyr Phe Phe 170 175 180 gat cct tct ggc cag gtg ttg gtg ggg gat cgg cgt tgg ttg ttc aat 691 Asp Pro Ser Gly Gln Val Leu Val Gly Asp Arg Arg Trp Leu Phe Asn 185 190 195 gag tcg cag tcg atg tcc acg gtg ctg atg gcc ctt ctg gtt aat ggt 739 Glu Ser Gln Ser Met Ser Thr Val Leu Met Ala Leu Leu Val Asn Gly 200 205 210 cct tcg ccg gca att tct cct ggt gtg gtc aat cag ctg tcc acg gat 787 Pro Ser Pro Ala Ile Ser Pro Gly Val Val Asn Gln Leu Ser Thr Asp 215 220 225 gcg tcg ttc gtg ggg ttc aat gat ggg gag tat cag ttc act ggt ttg 835 Ala Ser Phe Val Gly Phe Asn Asp Gly Glu Tyr Gln Phe Thr Gly Leu 230 235 240 245 gga aat ttg gat gat gat gcg cgt ttg cgt ttc gcc gcc cag gcc gtg 883 Gly Asn Leu Asp Asp Asp Ala Arg Leu Arg Phe Ala Ala Gln Ala Val 250 255 260 tgg acg ttg gcg cat gct gat gtc gca ggc ccc tac act ttg gtc gct 931 Trp Thr Leu Ala His Ala Asp Val Ala Gly Pro Tyr Thr Leu Val Ala 265 270 275 gac ggc gcg ccg ttg ctg tcg gag ttc cca acg ctc acc acc gat gac 979 Asp Gly Ala Pro Leu Leu Ser Glu Phe Pro Thr Leu Thr Thr Asp Asp 280 285 290 ctc gcc gaa tac aac cca gag gct tac acc aac acg gtg tcc acg ttg 1027 Leu Ala Glu Tyr Asn Pro Glu Ala Tyr Thr Asn Thr Val Ser Thr Leu 295 300 305 ttt gcg ttg cag gat gga tcg ttg tcg agg gtc agt tcc ggc aat gtg 1075 Phe Ala Leu Gln Asp Gly Ser Leu Ser Arg Val Ser Ser Gly Asn Val 310 315 320 325 agt cca cta cag ggc att tgg agc ggt gga gat atc gat tct gca gcg 1123 Ser Pro Leu Gln Gly Ile Trp Ser Gly Gly Asp Ile Asp Ser Ala Ala 330 335 340 att tcc tcc tcc gcc aat gtg gtg gca gcg gta cgc cac gaa aac aac 1171 Ile Ser Ser Ser Ala Asn Val Val Ala Ala Val Arg His Glu Asn Asn 345 350 355 gag gca gtg ctt act gtt ggc tcc atg gaa ggc gtg act tca gat gcg 1219 Glu Ala Val Leu Thr Val Gly Ser Met Glu Gly Val Thr Ser Asp Ala 360 365 370 ttg agg agt gaa acg atc act cgt ccc acc ttt gaa tac gcg tcg agt 1267 Leu Arg Ser Glu Thr Ile Thr Arg Pro Thr Phe Glu Tyr Ala Ser Ser 375 380 385 ggg ttg tgg gct gtg gtg gat ggg gag acg cct gtc cga gtc gca cga 1315 Gly Leu Trp Ala Val Val Asp Gly Glu Thr Pro Val Arg Val Ala Arg 390 395 400 405 tcg gca aca acc ggt gag ctc gtc cag acg gag gcg gag att gtg ctg 1363 Ser Ala Thr Thr Gly Glu Leu Val Gln Thr Glu Ala Glu Ile Val Leu 410 415 420 cca agg gat gtg acg ggt ccg atc tct gaa ttc caa ctg tca cga act 1411 Pro Arg Asp Val Thr Gly Pro Ile Ser Glu Phe Gln Leu Ser Arg Thr 425 430 435 ggg gtc cgg gcc gcc atg atc att gaa ggc aag gtg tac gtg ggc gtc 1459 Gly Val Arg Ala Ala Met Ile Ile Glu Gly Lys Val Tyr Val Gly Val 440 445 450 gta acg cgt cct ggt ccg ggc gag cgg cgc gtg aca aat atc acg gag 1507 Val Thr Arg Pro Gly Pro Gly Glu Arg Arg Val Thr Asn Ile Thr Glu 455 460 465 gtg gcg ccg agc ttg ggc gag gcg gcg ctg tcg atc aac tgg cgc cca 1555 Val Ala Pro Ser Leu Gly Glu Ala Ala Leu Ser Ile Asn Trp Arg Pro 470 475 480 485 gac ggc att ttg ctt gtg ggc acg tca att cca gag acg ccg ctg tgg 1603 Asp Gly Ile Leu Leu Val Gly Thr Ser Ile Pro Glu Thr Pro Leu Trp 490 495 500 cgc gtc gag cag gac gga tcg gcg att tcg tcg atg ccg agc ggg aat 1651 Arg Val Glu Gln Asp Gly Ser Ala Ile Ser Ser Met Pro Ser Gly Asn 505 510 515 ctc agc gcg ccg gtg gtg gcg gtg gca agt tcc gcg acg acg gtc tac 1699 Leu Ser Ala Pro Val Val Ala Val Ala Ser Ser Ala Thr Thr Val Tyr 520 525 530 gtc act gat tcg cat gcg atg ctt cag ctg ccg act gcc gat aat gat 1747 Val Thr Asp Ser His Ala Met Leu Gln Leu Pro Thr Ala Asp Asn Asp 535 540 545 att tgg cgc gag gtg ccc ggt ttg ctg ggc acg cgt gcg gcg ccg gtg 1795 Ile Trp Arg Glu Val Pro Gly Leu Leu Gly Thr Arg Ala Ala Pro Val 550 555 560 565 gtt gcg tac tgatggagct gttcttcccg cgc 1827 Val Ala Tyr <210> 1134 <211> 568 <212> PRT <213> Corynebacterium glutamicum <400> 1134 Val Ser Lys Ile Ser Thr Lys Leu Lys Ala Leu Thr Ala Val Leu Ser 1 5 10 15 Val Thr Thr Leu Val Ala Gly Cys Ser Thr Leu Pro Gln Asn Thr Asp 20 25 30 Pro Gln Val Leu Arg Ser Phe Ser Gly Ser Gln Ser Thr Gln Glu Ile 35 40 45 Ala Gly Pro Thr Pro Asn Gln Asp Pro Asp Leu Leu Ile Arg Gly Phe 50 55 60 Phe Ser Ala Gly Ala Tyr Pro Thr Gln Gln Tyr Glu Ala Ala Lys Ala 65 70 75 80 Tyr Leu Thr Glu Gly Thr Arg Ser Thr Trp Asn Pro Ala Ala Ser Thr 85 90 95 Arg Ile Leu Asp Arg Ile Asp Leu Asn Thr Leu Pro Gly Ser Thr Asn 100 105 110 Ala Glu Arg Thr Ile Ala Ile Arg Gly Thr Gln Val Gly Thr Leu Leu 115 120 125 Ser Gly Gly Val Tyr Gln Pro Glu Asn Ala Glu Phe Glu Ala Glu Ile 130 135 140 Thr Met Arg Arg Glu Asp Gly Glu Trp Arg Ile Asp Ala Leu Pro Asp 145 150 155 160 Gly Ile Leu Leu Glu Arg Asn Asp Leu Arg Asn His Tyr Thr Pro His 165 170 175 Asp Val Tyr Phe Phe Asp Pro Ser Gly Gln Val Leu Val Gly Asp Arg 180 185 190 Arg Trp Leu Phe Asn Glu Ser Gln Ser Met Ser Thr Val Leu Met Ala 195 200 205 Leu Leu Val Asn Gly Pro Ser Pro Ala Ile Ser Pro Gly Val Val Asn 210 215 220 Gln Leu Ser Thr Asp Ala Ser Phe Val Gly Phe Asn Asp Gly Glu Tyr 225 230 235 240 Gln Phe Thr Gly Leu Gly Asn Leu Asp Asp Asp Ala Arg Leu Arg Phe 245 250 255 Ala Ala Gln Ala Val Trp Thr Leu Ala His Ala Asp Val Ala Gly Pro 260 265 270 Tyr Thr Leu Val Ala Asp Gly Ala Pro Leu Leu Ser Glu Phe Pro Thr 275 280 285 Leu Thr Thr Asp Asp Leu Ala Glu Tyr Asn Pro Glu Ala Tyr Thr Asn 290 295 300 Thr Val Ser Thr Leu Phe Ala Leu Gln Asp Gly Ser Leu Ser Arg Val 305 310 315 320 Ser Ser Gly Asn Val Ser Pro Leu Gln Gly Ile Trp Ser Gly Gly Asp 325 330 335 Ile Asp Ser Ala Ala Ile Ser Ser Ser Ala Asn Val Val Ala Ala Val 340 345 350 Arg His Glu Asn Asn Glu Ala Val Leu Thr Val Gly Ser Met Glu Gly 355 360 365 Val Thr Ser Asp Ala Leu Arg Ser Glu Thr Ile Thr Arg Pro Thr Phe 370 375 380 Glu Tyr Ala Ser Ser Gly Leu Trp Ala Val Val Asp Gly Glu Thr Pro 385 390 395 400 Val Arg Val Ala Arg Ser Ala Thr Thr Gly Glu Leu Val Gln Thr Glu 405 410 415 Ala Glu Ile Val Leu Pro Arg Asp Val Thr Gly Pro Ile Ser Glu Phe 420 425 430 Gln Leu Ser Arg Thr Gly Val Arg Ala Ala Met Ile Ile Glu Gly Lys 435 440 445 Val Tyr Val Gly Val Val Thr Arg Pro Gly Pro Gly Glu Arg Arg Val 450 455 460 Thr Asn Ile Thr Glu Val Ala Pro Ser Leu Gly Glu Ala Ala Leu Ser 465 470 475 480 Ile Asn Trp Arg Pro Asp Gly Ile Leu Leu Val Gly Thr Ser Ile Pro 485 490 495 Glu Thr Pro Leu Trp Arg Val Glu Gln Asp Gly Ser Ala Ile Ser Ser 500 505 510 Met Pro Ser Gly Asn Leu Ser Ala Pro Val Val Ala Val Ala Ser Ser 515 520 525 Ala Thr Thr Val Tyr Val Thr Asp Ser His Ala Met Leu Gln Leu Pro 530 535 540 Thr Ala Asp Asn Asp Ile Trp Arg Glu Val Pro Gly Leu Leu Gly Thr 545 550 555 560 Arg Ala Ala Pro Val Val Ala Tyr 565 <210> 1135 <211> 555 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(532) <223> RXC01709 <400> 1135 gcaagtggaa ccacgatggg aacggtaact gctgccgctg cggtattact cgtagtttca 60 gaaattaggt gtcgatgcag caatacggaa ctttgccaat gtg ttt gaa caa gct 115 Val Phe Glu Gln Ala 1 5 ctc ggg ctc acc acc ctt gca caa aca gct gga gcg ggc gca gcg ggg 163 Leu Gly Leu Thr Thr Leu Ala Gln Thr Ala Gly Ala Gly Ala Ala Gly 10 15 20 ggc ttg ggt ttc atg gca atg gcg ttg ttg tct gca ggg atg cgc tcc 211 Gly Leu Gly Phe Met Ala Met Ala Leu Leu Ser Ala Gly Met Arg Ser 25 30 35 ggc gtg gac atg att ctt aat gaa acc ggg ggt gaa aag atg ctt gca 259 Gly Val Asp Met Ile Leu Asn Glu Thr Gly Gly Glu Lys Met Leu Ala 40 45 50 cag gca gat tta gtc atc act gga gaa gga cgc att gat gca cag acc 307 Gln Ala Asp Leu Val Ile Thr Gly Glu Gly Arg Ile Asp Ala Gln Thr 55 60 65 ctc agc ggg aaa gct cct act gga atc gcc aaa cgg gca cgt gcg aaa 355 Leu Ser Gly Lys Ala Pro Thr Gly Ile Ala Lys Arg Ala Arg Ala Lys 70 75 80 85 gga att cca gta ctg gcg gtt tgt ggg cag agc cta ttg ggt cca gca 403 Gly Ile Pro Val Leu Ala Val Cys Gly Gln Ser Leu Leu Gly Pro Ala 90 95 100 atc tca aat gag cta ttt gaa gac atc tac agc ttt acc gat ttc gaa 451 Ile Ser Asn Glu Leu Phe Glu Asp Ile Tyr Ser Phe Thr Asp Phe Glu 105 110 115 tct gac atc aat gaa tgc att cga aac ccg ctc cca att ttg gaa ggt 499 Ser Asp Ile Asn Glu Cys Ile Arg Asn Pro Leu Pro Ile Leu Glu Gly 120 125 130 atc ggt ttt aac atc gcc aaa cat cat ctg agt tagcgatatt tcagcaaacc 552 Ile Gly Phe Asn Ile Ala Lys His His Leu Ser 135 140 gat 555 <210> 1136 <211> 144 <212> PRT <213> Corynebacterium glutamicum <400> 1136 Val Phe Glu Gln Ala Leu Gly Leu Thr Thr Leu Ala Gln Thr Ala Gly 1 5 10 15 Ala Gly Ala Ala Gly Gly Leu Gly Phe Met Ala Met Ala Leu Leu Ser 20 25 30 Ala Gly Met Arg Ser Gly Val Asp Met Ile Leu Asn Glu Thr Gly Gly 35 40 45 Glu Lys Met Leu Ala Gln Ala Asp Leu Val Ile Thr Gly Glu Gly Arg 50 55 60 Ile Asp Ala Gln Thr Leu Ser Gly Lys Ala Pro Thr Gly Ile Ala Lys 65 70 75 80 Arg Ala Arg Ala Lys Gly Ile Pro Val Leu Ala Val Cys Gly Gln Ser 85 90 95 Leu Leu Gly Pro Ala Ile Ser Asn Glu Leu Phe Glu Asp Ile Tyr Ser 100 105 110 Phe Thr Asp Phe Glu Ser Asp Ile Asn Glu Cys Ile Arg Asn Pro Leu 115 120 125 Pro Ile Leu Glu Gly Ile Gly Phe Asn Ile Ala Lys His His Leu Ser 130 135 140 <210> 1137 <211> 898 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(898) <223> RXC02207 <400> 1137 gaatcggtga ctttgccaac accaatcaca caagcccttg atgatgtctc cctgtgactt 60 ggtccaatta cattcactgg taatctgaaa ccttgtgaat atg cgc cgt cga tcc 115 Met Arg Arg Arg Ser 1 5 cgt gtg tcc cgt ttg ctt ccc gcc aca gct ttg ctg gcc tca act gca 163 Arg Val Ser Arg Leu Leu Pro Ala Thr Ala Leu Leu Ala Ser Thr Ala 10 15 20 ctt ctt tta agt gca tgt acg caa ggg gta acg gac tcc ccg gat atg 211 Leu Leu Leu Ser Ala Cys Thr Gln Gly Val Thr Asp Ser Pro Asp Met 25 30 35 ggc aag gca act ccc gct gtc tcc ccc gca gca agc aac ccg gat ggc 259 Gly Lys Ala Thr Pro Ala Val Ser Pro Ala Ala Ser Asn Pro Asp Gly 40 45 50 caa gta att gag ttc ggc aac atc act gac atg gaa gtc act gat ggt 307 Gln Val Ile Glu Phe Gly Asn Ile Thr Asp Met Glu Val Thr Asp Gly 55 60 65 gac atc ctc ggt gta cgc acc gaa gac gca ctc gct att ggt aca gtc 355 Asp Ile Leu Gly Val Arg Thr Glu Asp Ala Leu Ala Ile Gly Thr Val 70 75 80 85 tcc gac ttc gaa gcg ggt agc cag gtg gaa ctg gac gtc gat aag caa 403 Ser Asp Phe Glu Ala Gly Ser Gln Val Glu Leu Asp Val Asp Lys Gln 90 95 100 tgc ggc gac ctg acc gca acc ggc ggc act ttc gtg ctc ccc tgc gcc 451 Cys Gly Asp Leu Thr Ala Thr Gly Gly Thr Phe Val Leu Pro Cys Ala 105 110 115 gat ggc gtt tat ttg att gat gcc aag gac ccg gat ctg gat gag ttg 499 Asp Gly Val Tyr Leu Ile Asp Ala Lys Asp Pro Asp Leu Asp Glu Leu 120 125 130 cgt gca act gac aag cca gtc acg gtg gca gcc ttg acc agc gat gat 547 Arg Ala Thr Asp Lys Pro Val Thr Val Ala Ala Leu Thr Ser Asp Asp 135 140 145 cag ctt ctg gtg ggc aat ggt gaa gat gaa gaa ctc acc atc tac cgc 595 Gln Leu Leu Val Gly Asn Gly Glu Asp Glu Glu Leu Thr Ile Tyr Arg 150 155 160 165 gag ggc gaa gag cca gaa acc ttc acc gtc gcg ggt ccc aat acc cag 643 Glu Gly Glu Glu Pro Glu Thr Phe Thr Val Ala Gly Pro Asn Thr Gln 170 175 180 ctc atc gcc gtt cct gtc att gat cgc cac gac gcc gtt gtg cgc acc 691 Leu Ile Ala Val Pro Val Ile Asp Arg His Asp Ala Val Val Arg Thr 185 190 195 tgg aac gaa aac acc acg att caa gat gtg gac tac ccc aac gac cgt 739 Trp Asn Glu Asn Thr Thr Ile Gln Asp Val Asp Tyr Pro Asn Asp Arg 200 205 210 gaa ggc gcg acc ctt cgc gtg gga ctc ggc gtt ggt caa atg gct ggt 787 Glu Gly Ala Thr Leu Arg Val Gly Leu Gly Val Gly Gln Met Ala Gly 215 220 225 ggc gaa gac ggc ctg ctg gtg gtc tct gat gaa atg ggt ggc caa att 835 Gly Glu Asp Gly Leu Leu Val Val Ser Asp Glu Met Gly Gly Gln Ile 230 235 240 245 gcc atc tac aac gct gat gat gtc atc cga ctt caa aat gac cgc ccc 883 Ala Ile Tyr Asn Ala Asp Asp Val Ile Arg Leu Gln Asn Asp Arg Pro 250 255 260 cac cga cga gga acc 898 His Arg Arg Gly Thr 265 <210> 1138 <211> 266 <212> PRT <213> Corynebacterium glutamicum <400> 1138 Met Arg Arg Arg Ser Arg Val Ser Arg Leu Leu Pro Ala Thr Ala Leu 1 5 10 15 Leu Ala Ser Thr Ala Leu Leu Leu Ser Ala Cys Thr Gln Gly Val Thr 20 25 30 Asp Ser Pro Asp Met Gly Lys Ala Thr Pro Ala Val Ser Pro Ala Ala 35 40 45 Ser Asn Pro Asp Gly Gln Val Ile Glu Phe Gly Asn Ile Thr Asp Met 50 55 60 Glu Val Thr Asp Gly Asp Ile Leu Gly Val Arg Thr Glu Asp Ala Leu 65 70 75 80 Ala Ile Gly Thr Val Ser Asp Phe Glu Ala Gly Ser Gln Val Glu Leu 85 90 95 Asp Val Asp Lys Gln Cys Gly Asp Leu Thr Ala Thr Gly Gly Thr Phe 100 105 110 Val Leu Pro Cys Ala Asp Gly Val Tyr Leu Ile Asp Ala Lys Asp Pro 115 120 125 Asp Leu Asp Glu Leu Arg Ala Thr Asp Lys Pro Val Thr Val Ala Ala 130 135 140 Leu Thr Ser Asp Asp Gln Leu Leu Val Gly Asn Gly Glu Asp Glu Glu 145 150 155 160 Leu Thr Ile Tyr Arg Glu Gly Glu Glu Pro Glu Thr Phe Thr Val Ala 165 170 175 Gly Pro Asn Thr Gln Leu Ile Ala Val Pro Val Ile Asp Arg His Asp 180 185 190 Ala Val Val Arg Thr Trp Asn Glu Asn Thr Thr Ile Gln Asp Val Asp 195 200 205 Tyr Pro Asn Asp Arg Glu Gly Ala Thr Leu Arg Val Gly Leu Gly Val 210 215 220 Gly Gln Met Ala Gly Gly Glu Asp Gly Leu Leu Val Val Ser Asp Glu 225 230 235 240 Met Gly Gly Gln Ile Ala Ile Tyr Asn Ala Asp Asp Val Ile Arg Leu 245 250 255 Gln Asn Asp Arg Pro His Arg Arg Gly Thr 260 265 <210> 1139 <211> 891 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(868) <223> RXA00347 <400> 1139 tcggccagca atccgcttgg tgtcctggat cgcgccgaca tcttaaggtg ccagggcttt 60 aaagtgccag gggttctgtg ggatccgtac actggttccc atg act ttg act att 115 Met Thr Leu Thr Ile 1 5 gag gaa atc gcc aag acc aaa aag ctt ttg gtt gtg tcc gat ttt gat 163 Glu Glu Ile Ala Lys Thr Lys Lys Leu Leu Val Val Ser Asp Phe Asp 10 15 20 gga acc atc gca gga ttt agc aag gac gct tac aac gtt cct atc aac 211 Gly Thr Ile Ala Gly Phe Ser Lys Asp Ala Tyr Asn Val Pro Ile Asn 25 30 35 cag aaa tcc ctc aag gcg gta aaa gac ctc tcc caa caa gca gac act 259 Gln Lys Ser Leu Lys Ala Val Lys Asp Leu Ser Gln Gln Ala Asp Thr 40 45 50 gat gtt gtc att ttg tcg gga cgt cac ctg gag gga ttg aag acg gtt 307 Asp Val Val Ile Leu Ser Gly Arg His Leu Glu Gly Leu Lys Thr Val 55 60 65 ctt gat ctt ggt cag tac gac atc acc atg gtg ggt tca cac ggt tct 355 Leu Asp Leu Gly Gln Tyr Asp Ile Thr Met Val Gly Ser His Gly Ser 70 75 80 85 gag gat tcc tcc cgc ccg cgt acc ctc act cct gaa gag gta gct cgc 403 Glu Asp Ser Ser Arg Pro Arg Thr Leu Thr Pro Glu Glu Val Ala Arg 90 95 100 ctc gcc aag att gaa gca gat ctg gaa aag atc gtc gac ggc atc gaa 451 Leu Ala Lys Ile Glu Ala Asp Leu Glu Lys Ile Val Asp Gly Ile Glu 105 110 115 ggc gca ttc gtg gag atc aag cct ttc cac cgc gtg ctg cac ttc atc 499 Gly Ala Phe Val Glu Ile Lys Pro Phe His Arg Val Leu His Phe Ile 120 125 130 cgt gtt tcc gac aag gac aaa gtc caa gga atc ctc gcc caa gca gca 547 Arg Val Ser Asp Lys Asp Lys Val Gln Gly Ile Leu Ala Gln Ala Ala 135 140 145 cac gta gac tct tcc ggc ctg aag gtt act aac ggc aag agc atc atc 595 His Val Asp Ser Ser Gly Leu Lys Val Thr Asn Gly Lys Ser Ile Ile 150 155 160 165 gaa tac tcc atc agc tcc acc acc aag ggc acc tgg ctg aag gaa tac 643 Glu Tyr Ser Ile Ser Ser Thr Thr Lys Gly Thr Trp Leu Lys Glu Tyr 170 175 180 gtt gac cgc acc gag ccc act ggt gtg att ttc ctc ggc gat gac acc 691 Val Asp Arg Thr Glu Pro Thr Gly Val Ile Phe Leu Gly Asp Asp Thr 185 190 195 acc gat gag cac ggt ttc aaa gct tta gaa aac gat gat cgt gcc cta 739 Thr Asp Glu His Gly Phe Lys Ala Leu Glu Asn Asp Asp Arg Ala Leu 200 205 210 acc gtc aag gtt ggc gaa gga gac act gca gcc aaa acc cgc gtc gac 787 Thr Val Lys Val Gly Glu Gly Asp Thr Ala Ala Lys Thr Arg Val Asp 215 220 225 gat gtt gat aat gtg gga att ttc cta gag aaa ctc gcc tac cac cgc 835 Asp Val Asp Asn Val Gly Ile Phe Leu Glu Lys Leu Ala Tyr His Arg 230 235 240 245 atg cag tat gcg gaa agc gtg cga ttg ggg att taagagagcc taaacgcacg 888 Met Gln Tyr Ala Glu Ser Val Arg Leu Gly Ile 250 255 aaa 891 <210> 1140 <211> 256 <212> PRT <213> Corynebacterium glutamicum <400> 1140 Met Thr Leu Thr Ile Glu Glu Ile Ala Lys Thr Lys Lys Leu Leu Val 1 5 10 15 Val Ser Asp Phe Asp Gly Thr Ile Ala Gly Phe Ser Lys Asp Ala Tyr 20 25 30 Asn Val Pro Ile Asn Gln Lys Ser Leu Lys Ala Val Lys Asp Leu Ser 35 40 45 Gln Gln Ala Asp Thr Asp Val Val Ile Leu Ser Gly Arg His Leu Glu 50 55 60 Gly Leu Lys Thr Val Leu Asp Leu Gly Gln Tyr Asp Ile Thr Met Val 65 70 75 80 Gly Ser His Gly Ser Glu Asp Ser Ser Arg Pro Arg Thr Leu Thr Pro 85 90 95 Glu Glu Val Ala Arg Leu Ala Lys Ile Glu Ala Asp Leu Glu Lys Ile 100 105 110 Val Asp Gly Ile Glu Gly Ala Phe Val Glu Ile Lys Pro Phe His Arg 115 120 125 Val Leu His Phe Ile Arg Val Ser Asp Lys Asp Lys Val Gln Gly Ile 130 135 140 Leu Ala Gln Ala Ala His Val Asp Ser Ser Gly Leu Lys Val Thr Asn 145 150 155 160 Gly Lys Ser Ile Ile Glu Tyr Ser Ile Ser Ser Thr Thr Lys Gly Thr 165 170 175 Trp Leu Lys Glu Tyr Val Asp Arg Thr Glu Pro Thr Gly Val Ile Phe 180 185 190 Leu Gly Asp Asp Thr Thr Asp Glu His Gly Phe Lys Ala Leu Glu Asn 195 200 205 Asp Asp Arg Ala Leu Thr Val Lys Val Gly Glu Gly Asp Thr Ala Ala 210 215 220 Lys Thr Arg Val Asp Asp Val Asp Asn Val Gly Ile Phe Leu Glu Lys 225 230 235 240 Leu Ala Tyr His Arg Met Gln Tyr Ala Glu Ser Val Arg Leu Gly Ile 245 250 255 <210> 1141 <211> 2556 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2533) <223> RXN01239 <400> 1141 gcacttgctg cgtaaatctt tttcccacgc cgggaatgcg tgaacactaa gatcgaggac 60 gtaccgcacg attttgccta acttttaagg gtgtttcatc atg gca cgt cca att 115 Met Ala Arg Pro Ile 1 5 tcc gca acg tac agg ctt caa atg cga gga cct caa gca gat agc gcc 163 Ser Ala Thr Tyr Arg Leu Gln Met Arg Gly Pro Gln Ala Asp Ser Ala 10 15 20 ggg cgt tca ttt ggt ttt gcg cag gcc aaa gcc cag ctt ccc tat ctg 211 Gly Arg Ser Phe Gly Phe Ala Gln Ala Lys Ala Gln Leu Pro Tyr Leu 25 30 35 aag aag cta ggc atc agc cac ctg tac ctc tcc cct att ttt acg gcc 259 Lys Lys Leu Gly Ile Ser His Leu Tyr Leu Ser Pro Ile Phe Thr Ala 40 45 50 atg cca gat tcc aat cat ggc tac gat gtc att gat ccc acc acc atc 307 Met Pro Asp Ser Asn His Gly Tyr Asp Val Ile Asp Pro Thr Thr Ile 55 60 65 aat gaa gag ctc ggt ggc atg gag ggt ctt cga gat ctt gcc gca gct 355 Asn Glu Glu Leu Gly Gly Met Glu Gly Leu Arg Asp Leu Ala Ala Ala 70 75 80 85 aca cac gag ttg ggc atg ggc atc atc att gat att gtt ccc aac cat 403 Thr His Glu Leu Gly Met Gly Ile Ile Ile Asp Ile Val Pro Asn His 90 95 100 tta ggt gtt gcc gtt cca cat ttg aat cct tgg tgg tgg gat gtt cta 451 Leu Gly Val Ala Val Pro His Leu Asn Pro Trp Trp Trp Asp Val Leu 105 110 115 aaa aac ggc aaa gat tcc gct ttt gag ttc tat ttc gat att gac tgg 499 Lys Asn Gly Lys Asp Ser Ala Phe Glu Phe Tyr Phe Asp Ile Asp Trp 120 125 130 cac gaa gac aac ggt tct ggt ggc aag ctg ggc atg ccg att ctg ggt 547 His Glu Asp Asn Gly Ser Gly Gly Lys Leu Gly Met Pro Ile Leu Gly 135 140 145 gct gaa ggc gat gaa gac aag ctg gaa ttc gcg gag ctt gat gga gag 595 Ala Glu Gly Asp Glu Asp Lys Leu Glu Phe Ala Glu Leu Asp Gly Glu 150 155 160 165 aaa gtg ctc aaa tat ttt gac cac ctc ttc cca atc gcg cct ggt acc 643 Lys Val Leu Lys Tyr Phe Asp His Leu Phe Pro Ile Ala Pro Gly Thr 170 175 180 gaa gaa ggg aca ccg caa gaa gtc tac aag cgc cag cat tac cgc ctg 691 Glu Glu Gly Thr Pro Gln Glu Val Tyr Lys Arg Gln His Tyr Arg Leu 185 190 195 cag ttc tgg cgc gat ggc gtg atc aac ttc cgt cgc ttc ttt tcc gtg 739 Gln Phe Trp Arg Asp Gly Val Ile Asn Phe Arg Arg Phe Phe Ser Val 200 205 210 aat acg ttg gct ggc atc agg caa gaa gat ccc tta gtg ttt gaa cat 787 Asn Thr Leu Ala Gly Ile Arg Gln Glu Asp Pro Leu Val Phe Glu His 215 220 225 act cat cgt ctg ctg cgc gaa ttg gtg gcg gaa gac ctc att gac ggc 835 Thr His Arg Leu Leu Arg Glu Leu Val Ala Glu Asp Leu Ile Asp Gly 230 235 240 245 gtg cgc gtc gat cac ccc gac ggg ctt tcc gat cct ttt gga tat ctg 883 Val Arg Val Asp His Pro Asp Gly Leu Ser Asp Pro Phe Gly Tyr Leu 250 255 260 cac aga ctc cgc gac ctc att gga cct gac cgc tgg ctg atc atc gaa 931 His Arg Leu Arg Asp Leu Ile Gly Pro Asp Arg Trp Leu Ile Ile Glu 265 270 275 aag atc ttg agc gtt gat gaa cca ctc gat ccc cgc ctg gcc gtt gat 979 Lys Ile Leu Ser Val Asp Glu Pro Leu Asp Pro Arg Leu Ala Val Asp 280 285 290 ggc acc act ggc tac gac gcc ctc cgt gaa ctc gac ggc gtg ttt atc 1027 Gly Thr Thr Gly Tyr Asp Ala Leu Arg Glu Leu Asp Gly Val Phe Ile 295 300 305 tcc cga gaa tct gag gac aaa ttc tcc atg ctg gcg ctg acc cac agt 1075 Ser Arg Glu Ser Glu Asp Lys Phe Ser Met Leu Ala Leu Thr His Ser 310 315 320 325 gga tcc acc tgg gat gaa cgc gcc ctc aaa tcc acg gag gaa agc ctc 1123 Gly Ser Thr Trp Asp Glu Arg Ala Leu Lys Ser Thr Glu Glu Ser Leu 330 335 340 aaa cga gtc gtc gcc caa caa gaa ctc gca gcc gaa atc tta agg ctc 1171 Lys Arg Val Val Ala Gln Gln Glu Leu Ala Ala Glu Ile Leu Arg Leu 345 350 355 gcc cgc gcc atg cgc cgc gat aac ttc tcc acc gca ggc acc aac gtc 1219 Ala Arg Ala Met Arg Arg Asp Asn Phe Ser Thr Ala Gly Thr Asn Val 360 365 370 acc gaa gac aaa ctt agc gaa acc atc atc gaa tta gtc gcc gcc atg 1267 Thr Glu Asp Lys Leu Ser Glu Thr Ile Ile Glu Leu Val Ala Ala Met 375 380 385 ccc gtc tac cgc gcc gac tac atc tcc ctc tca cgc acc acc gcc acc 1315 Pro Val Tyr Arg Ala Asp Tyr Ile Ser Leu Ser Arg Thr Thr Ala Thr 390 395 400 405 gtc atc gcg gag atg tcc aaa cgc ttc ccc tcc cgg cgt gac gca ctc 1363 Val Ile Ala Glu Met Ser Lys Arg Phe Pro Ser Arg Arg Asp Ala Leu 410 415 420 gac ctc atc gcg gcc gcc cta ctt ggc aat ggc gag gcc aaa atc cgc 1411 Asp Leu Ile Ala Ala Ala Leu Leu Gly Asn Gly Glu Ala Lys Ile Arg 425 430 435 ttc gct caa gtc tgc ggc gcc gtc atg gct aaa ggt gtg gaa gac acc 1459 Phe Ala Gln Val Cys Gly Ala Val Met Ala Lys Gly Val Glu Asp Thr 440 445 450 acc ttc tac cgc gca tct agg ctc gtt gca ttg caa gaa gtc ggt ggc 1507 Thr Phe Tyr Arg Ala Ser Arg Leu Val Ala Leu Gln Glu Val Gly Gly 455 460 465 gcg ccg ggg aga ttc ggc gtc tcc gct gca gaa ttc cac ttg ctg cag 1555 Ala Pro Gly Arg Phe Gly Val Ser Ala Ala Glu Phe His Leu Leu Gln 470 475 480 485 gaa gaa cgc agc ctg ctg tgg cca cgc acc atg acc acc ttg tcc acg 1603 Glu Glu Arg Ser Leu Leu Trp Pro Arg Thr Met Thr Thr Leu Ser Thr 490 495 500 cat gac acc aaa cgt ggc gaa gat acc cgc gcc cgc atc atc tcc ctg 1651 His Asp Thr Lys Arg Gly Glu Asp Thr Arg Ala Arg Ile Ile Ser Leu 505 510 515 tct gaa gtc ccc gat atg tac tcc gag ctg gtc aat cgt gtt ttc gcg 1699 Ser Glu Val Pro Asp Met Tyr Ser Glu Leu Val Asn Arg Val Phe Ala 520 525 530 gtg ctc ccc gcg cca gac ggc gca acg ggc agt ttc ctc cta caa aac 1747 Val Leu Pro Ala Pro Asp Gly Ala Thr Gly Ser Phe Leu Leu Gln Asn 535 540 545 ctg ctg ggc gta tgg ccc gcc gac ggc gtg atc acc gat gcg ctg cgc 1795 Leu Leu Gly Val Trp Pro Ala Asp Gly Val Ile Thr Asp Ala Leu Arg 550 555 560 565 gat cga ttc agg gaa tac gcc cta aaa gct atc cgc gaa gca tcc aca 1843 Asp Arg Phe Arg Glu Tyr Ala Leu Lys Ala Ile Arg Glu Ala Ser Thr 570 575 580 aaa acc acg tgg gtg gac ccc aac gag tcc ttc gag gct gcg gtc tgc 1891 Lys Thr Thr Trp Val Asp Pro Asn Glu Ser Phe Glu Ala Ala Val Cys 585 590 595 gat tgg gtg gaa gcg ctt ttc gac gga ccc tcc acc tca cta atc acc 1939 Asp Trp Val Glu Ala Leu Phe Asp Gly Pro Ser Thr Ser Leu Ile Thr 600 605 610 gaa ttt gtc tcc cac atc aac cgt ggc tct gtg caa atc tcc tta ggc 1987 Glu Phe Val Ser His Ile Asn Arg Gly Ser Val Gln Ile Ser Leu Gly 615 620 625 agg aaa ctg ctg caa atg gtg ggc gct gga atc ccc gac act tac caa 2035 Arg Lys Leu Leu Gln Met Val Gly Ala Gly Ile Pro Asp Thr Tyr Gln 630 635 640 645 gga act gag ttt tta gaa gac tcc ctg gta gat ccc gat aac cga cgc 2083 Gly Thr Glu Phe Leu Glu Asp Ser Leu Val Asp Pro Asp Asn Arg Arg 650 655 660 ttt gtt gat tac acc gcc aga gaa caa gtc ctg gag cgc ctg caa acc 2131 Phe Val Asp Tyr Thr Ala Arg Glu Gln Val Leu Glu Arg Leu Gln Thr 665 670 675 tgg gct tgg acg cag gtt aat tcg gta gaa gac ttg gtg gat aac gcc 2179 Trp Ala Trp Thr Gln Val Asn Ser Val Glu Asp Leu Val Asp Asn Ala 680 685 690 gac atc gcc aaa atg gcc gtg gtc cat aaa tcc ctc gag ttg cgt gct 2227 Asp Ile Ala Lys Met Ala Val Val His Lys Ser Leu Glu Leu Arg Ala 695 700 705 gaa ttt cgt gca agc ttt gtt ggt gga gat cat cag gca gta ttt ggc 2275 Glu Phe Arg Ala Ser Phe Val Gly Gly Asp His Gln Ala Val Phe Gly 710 715 720 725 gaa ggt cgc gca gaa tcc cac atc atg ggc atc gcc cgc ggt aca gac 2323 Glu Gly Arg Ala Glu Ser His Ile Met Gly Ile Ala Arg Gly Thr Asp 730 735 740 cga aac cac ctc aac atc att gct ctt gct acc cgt cga cca ctg atc 2371 Arg Asn His Leu Asn Ile Ile Ala Leu Ala Thr Arg Arg Pro Leu Ile 745 750 755 ttg gaa gac cgt ggc gga tgg tat gac acc acc gtc acg ctt cct ggt 2419 Leu Glu Asp Arg Gly Gly Trp Tyr Asp Thr Thr Val Thr Leu Pro Gly 760 765 770 gga caa tgg gaa gac agg ctc acc ggg caa cgc ttc agt ggt gtt gtc 2467 Gly Gln Trp Glu Asp Arg Leu Thr Gly Gln Arg Phe Ser Gly Val Val 775 780 785 cca gcc acc gat ttg ttc tca cat cta ccc gta tct ttg ttg gtt tta 2515 Pro Ala Thr Asp Leu Phe Ser His Leu Pro Val Ser Leu Leu Val Leu 790 795 800 805 gta ccc gat agt gag ttt tgatccctgc acaggaaagt tag 2556 Val Pro Asp Ser Glu Phe 810 <210> 1142 <211> 811 <212> PRT <213> Corynebacterium glutamicum <400> 1142 Met Ala Arg Pro Ile Ser Ala Thr Tyr Arg Leu Gln Met Arg Gly Pro 1 5 10 15 Gln Ala Asp Ser Ala Gly Arg Ser Phe Gly Phe Ala Gln Ala Lys Ala 20 25 30 Gln Leu Pro Tyr Leu Lys Lys Leu Gly Ile Ser His Leu Tyr Leu Ser 35 40 45 Pro Ile Phe Thr Ala Met Pro Asp Ser Asn His Gly Tyr Asp Val Ile 50 55 60 Asp Pro Thr Thr Ile Asn Glu Glu Leu Gly Gly Met Glu Gly Leu Arg 65 70 75 80 Asp Leu Ala Ala Ala Thr His Glu Leu Gly Met Gly Ile Ile Ile Asp 85 90 95 Ile Val Pro Asn His Leu Gly Val Ala Val Pro His Leu Asn Pro Trp 100 105 110 Trp Trp Asp Val Leu Lys Asn Gly Lys Asp Ser Ala Phe Glu Phe Tyr 115 120 125 Phe Asp Ile Asp Trp His Glu Asp Asn Gly Ser Gly Gly Lys Leu Gly 130 135 140 Met Pro Ile Leu Gly Ala Glu Gly Asp Glu Asp Lys Leu Glu Phe Ala 145 150 155 160 Glu Leu Asp Gly Glu Lys Val Leu Lys Tyr Phe Asp His Leu Phe Pro 165 170 175 Ile Ala Pro Gly Thr Glu Glu Gly Thr Pro Gln Glu Val Tyr Lys Arg 180 185 190 Gln His Tyr Arg Leu Gln Phe Trp Arg Asp Gly Val Ile Asn Phe Arg 195 200 205 Arg Phe Phe Ser Val Asn Thr Leu Ala Gly Ile Arg Gln Glu Asp Pro 210 215 220 Leu Val Phe Glu His Thr His Arg Leu Leu Arg Glu Leu Val Ala Glu 225 230 235 240 Asp Leu Ile Asp Gly Val Arg Val Asp His Pro Asp Gly Leu Ser Asp 245 250 255 Pro Phe Gly Tyr Leu His Arg Leu Arg Asp Leu Ile Gly Pro Asp Arg 260 265 270 Trp Leu Ile Ile Glu Lys Ile Leu Ser Val Asp Glu Pro Leu Asp Pro 275 280 285 Arg Leu Ala Val Asp Gly Thr Thr Gly Tyr Asp Ala Leu Arg Glu Leu 290 295 300 Asp Gly Val Phe Ile Ser Arg Glu Ser Glu Asp Lys Phe Ser Met Leu 305 310 315 320 Ala Leu Thr His Ser Gly Ser Thr Trp Asp Glu Arg Ala Leu Lys Ser 325 330 335 Thr Glu Glu Ser Leu Lys Arg Val Val Ala Gln Gln Glu Leu Ala Ala 340 345 350 Glu Ile Leu Arg Leu Ala Arg Ala Met Arg Arg Asp Asn Phe Ser Thr 355 360 365 Ala Gly Thr Asn Val Thr Glu Asp Lys Leu Ser Glu Thr Ile Ile Glu 370 375 380 Leu Val Ala Ala Met Pro Val Tyr Arg Ala Asp Tyr Ile Ser Leu Ser 385 390 395 400 Arg Thr Thr Ala Thr Val Ile Ala Glu Met Ser Lys Arg Phe Pro Ser 405 410 415 Arg Arg Asp Ala Leu Asp Leu Ile Ala Ala Ala Leu Leu Gly Asn Gly 420 425 430 Glu Ala Lys Ile Arg Phe Ala Gln Val Cys Gly Ala Val Met Ala Lys 435 440 445 Gly Val Glu Asp Thr Thr Phe Tyr Arg Ala Ser Arg Leu Val Ala Leu 450 455 460 Gln Glu Val Gly Gly Ala Pro Gly Arg Phe Gly Val Ser Ala Ala Glu 465 470 475 480 Phe His Leu Leu Gln Glu Glu Arg Ser Leu Leu Trp Pro Arg Thr Met 485 490 495 Thr Thr Leu Ser Thr His Asp Thr Lys Arg Gly Glu Asp Thr Arg Ala 500 505 510 Arg Ile Ile Ser Leu Ser Glu Val Pro Asp Met Tyr Ser Glu Leu Val 515 520 525 Asn Arg Val Phe Ala Val Leu Pro Ala Pro Asp Gly Ala Thr Gly Ser 530 535 540 Phe Leu Leu Gln Asn Leu Leu Gly Val Trp Pro Ala Asp Gly Val Ile 545 550 555 560 Thr Asp Ala Leu Arg Asp Arg Phe Arg Glu Tyr Ala Leu Lys Ala Ile 565 570 575 Arg Glu Ala Ser Thr Lys Thr Thr Trp Val Asp Pro Asn Glu Ser Phe 580 585 590 Glu Ala Ala Val Cys Asp Trp Val Glu Ala Leu Phe Asp Gly Pro Ser 595 600 605 Thr Ser Leu Ile Thr Glu Phe Val Ser His Ile Asn Arg Gly Ser Val 610 615 620 Gln Ile Ser Leu Gly Arg Lys Leu Leu Gln Met Val Gly Ala Gly Ile 625 630 635 640 Pro Asp Thr Tyr Gln Gly Thr Glu Phe Leu Glu Asp Ser Leu Val Asp 645 650 655 Pro Asp Asn Arg Arg Phe Val Asp Tyr Thr Ala Arg Glu Gln Val Leu 660 665 670 Glu Arg Leu Gln Thr Trp Ala Trp Thr Gln Val Asn Ser Val Glu Asp 675 680 685 Leu Val Asp Asn Ala Asp Ile Ala Lys Met Ala Val Val His Lys Ser 690 695 700 Leu Glu Leu Arg Ala Glu Phe Arg Ala Ser Phe Val Gly Gly Asp His 705 710 715 720 Gln Ala Val Phe Gly Glu Gly Arg Ala Glu Ser His Ile Met Gly Ile 725 730 735 Ala Arg Gly Thr Asp Arg Asn His Leu Asn Ile Ile Ala Leu Ala Thr 740 745 750 Arg Arg Pro Leu Ile Leu Glu Asp Arg Gly Gly Trp Tyr Asp Thr Thr 755 760 765 Val Thr Leu Pro Gly Gly Gln Trp Glu Asp Arg Leu Thr Gly Gln Arg 770 775 780 Phe Ser Gly Val Val Pro Ala Thr Asp Leu Phe Ser His Leu Pro Val 785 790 795 800 Ser Leu Leu Val Leu Val Pro Asp Ser Glu Phe 805 810 <210> 1143 <211> 2556 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(2533) <223> FRXA01239 <400> 1143 gcacttgctg cgtaaatctt tttcccacgc cgggaatgcg tgaacactaa gatcgaggac 60 gtaccgcacg attttgccta acttttaagg gtgtttcatc atg gca cgt cca att 115 Met Ala Arg Pro Ile 1 5 tcc gca acg tac agg ctt caa atg cga gga cct caa gca gat agc gcc 163 Ser Ala Thr Tyr Arg Leu Gln Met Arg Gly Pro Gln Ala Asp Ser Ala 10 15 20 ggg cgt tca ttt ggt ttt gcg cag gcc aaa gcc cag ctt ccc tat ctg 211 Gly Arg Ser Phe Gly Phe Ala Gln Ala Lys Ala Gln Leu Pro Tyr Leu 25 30 35 aag aag cta ggc atc agc cac ctg tac ctc tcc cct att ttt acg gcc 259 Lys Lys Leu Gly Ile Ser His Leu Tyr Leu Ser Pro Ile Phe Thr Ala 40 45 50 atg cca gat tcc aat cat ggc tac gat gtc att gat ccc acc acc atc 307 Met Pro Asp Ser Asn His Gly Tyr Asp Val Ile Asp Pro Thr Thr Ile 55 60 65 aat gaa gag ctc ggt ggc atg gag ggt ctt cga gat ctt gcc gca gct 355 Asn Glu Glu Leu Gly Gly Met Glu Gly Leu Arg Asp Leu Ala Ala Ala 70 75 80 85 aca cac gag ttg ggc atg ggc atc atc att gat att gtt ccc aac cat 403 Thr His Glu Leu Gly Met Gly Ile Ile Ile Asp Ile Val Pro Asn His 90 95 100 tta ggt gtt gcc gtt cca cat ttg aat cct tgg tgg tgg gat gtt cta 451 Leu Gly Val Ala Val Pro His Leu Asn Pro Trp Trp Trp Asp Val Leu 105 110 115 aaa aac ggc aaa gat tcc gct ttt gag ttc tat ttc gat att gac tgg 499 Lys Asn Gly Lys Asp Ser Ala Phe Glu Phe Tyr Phe Asp Ile Asp Trp 120 125 130 cac gaa gac aac ggt tct ggt ggc aag ctg ggc atg ccg att ctg ggt 547 His Glu Asp Asn Gly Ser Gly Gly Lys Leu Gly Met Pro Ile Leu Gly 135 140 145 gct gaa ggc gat gaa gac aag ctg gaa ttc gcg gag ctt gat gga gag 595 Ala Glu Gly Asp Glu Asp Lys Leu Glu Phe Ala Glu Leu Asp Gly Glu 150 155 160 165 aaa gtg ctc aaa tat ttt gac cac ctc ttc cca atc gcg cct ggt acc 643 Lys Val Leu Lys Tyr Phe Asp His Leu Phe Pro Ile Ala Pro Gly Thr 170 175 180 gaa gaa ggg aca ccg caa gaa gtc tac aag cgc cag cat tac cgc ctg 691 Glu Glu Gly Thr Pro Gln Glu Val Tyr Lys Arg Gln His Tyr Arg Leu 185 190 195 cag ttc tgg cgc gat ggc gtg atc aac ttc cgt cgc ttc ttt tcc gtg 739 Gln Phe Trp Arg Asp Gly Val Ile Asn Phe Arg Arg Phe Phe Ser Val 200 205 210 aat acg ttg gct ggc atc agg caa gaa gat ccc tta gtg ttt gaa cat 787 Asn Thr Leu Ala Gly Ile Arg Gln Glu Asp Pro Leu Val Phe Glu His 215 220 225 act cat cgt ctg ctg cgc gaa ttg gtg gcg gaa gac ctc att gac ggc 835 Thr His Arg Leu Leu Arg Glu Leu Val Ala Glu Asp Leu Ile Asp Gly 230 235 240 245 gtg cgc gtc gat cac ccc gac ggg ctt tcc gat cct ttt gga tat ctg 883 Val Arg Val Asp His Pro Asp Gly Leu Ser Asp Pro Phe Gly Tyr Leu 250 255 260 cac aga ctc cgc gac ctc att gga cct gac cgc tgg ctg atc atc gaa 931 His Arg Leu Arg Asp Leu Ile Gly Pro Asp Arg Trp Leu Ile Ile Glu 265 270 275 aag atc ttg agc gtt gat gaa cca ctc gat ccc cgc ctg gcc gtt gat 979 Lys Ile Leu Ser Val Asp Glu Pro Leu Asp Pro Arg Leu Ala Val Asp 280 285 290 ggc acc act ggc tac gac gcc ctc cgt gaa ctc gac ggc gtg ttt atc 1027 Gly Thr Thr Gly Tyr Asp Ala Leu Arg Glu Leu Asp Gly Val Phe Ile 295 300 305 tcc cga gaa tct gag gac aaa ttc tcc atg ctg gcg ctg acc cac agt 1075 Ser Arg Glu Ser Glu Asp Lys Phe Ser Met Leu Ala Leu Thr His Ser 310 315 320 325 gga tcc acc tgg gat gaa cgc gcc ctc aaa tcc acg gag gaa agc ctc 1123 Gly Ser Thr Trp Asp Glu Arg Ala Leu Lys Ser Thr Glu Glu Ser Leu 330 335 340 aaa cga gtc gtc gcc caa caa gaa ctc gca gcc gaa atc tta agg ctc 1171 Lys Arg Val Val Ala Gln Gln Glu Leu Ala Ala Glu Ile Leu Arg Leu 345 350 355 gcc cgc gcc atg cgc cgc gat aac ttc tcc acc gca ggc acc aac gtc 1219 Ala Arg Ala Met Arg Arg Asp Asn Phe Ser Thr Ala Gly Thr Asn Val 360 365 370 acc gaa gac aaa ctt agc gaa acc atc atc gaa tta gtc gcc gcc atg 1267 Thr Glu Asp Lys Leu Ser Glu Thr Ile Ile Glu Leu Val Ala Ala Met 375 380 385 ccc gtc tac cgc gcc gac tac atc tcc ctc tca cgc acc acc gcc acc 1315 Pro Val Tyr Arg Ala Asp Tyr Ile Ser Leu Ser Arg Thr Thr Ala Thr 390 395 400 405 gtc atc gcg gag atg tcc aaa cgc ttc ccc tcc cgg cgt gac gca ctc 1363 Val Ile Ala Glu Met Ser Lys Arg Phe Pro Ser Arg Arg Asp Ala Leu 410 415 420 gac ctc atc gcg gcc gcc cta ctt ggc aat ggc gag gcc aaa atc cgc 1411 Asp Leu Ile Ala Ala Ala Leu Leu Gly Asn Gly Glu Ala Lys Ile Arg 425 430 435 ttc gct caa gtc tgc ggc gcc gtc atg gct aaa ggt gtg gaa gac acc 1459 Phe Ala Gln Val Cys Gly Ala Val Met Ala Lys Gly Val Glu Asp Thr 440 445 450 acc ttc tac cgc gca tct agg ctc gtt gca ttg caa gaa gtc ggt ggc 1507 Thr Phe Tyr Arg Ala Ser Arg Leu Val Ala Leu Gln Glu Val Gly Gly 455 460 465 gcg ccg ggg aga ttc ggc gtc tcc gct gca gaa ttc cac ttg ctg cag 1555 Ala Pro Gly Arg Phe Gly Val Ser Ala Ala Glu Phe His Leu Leu Gln 470 475 480 485 gaa gaa cgc agc ctg ctg tgg cca cgc acc atg acc acc ttg tcc acg 1603 Glu Glu Arg Ser Leu Leu Trp Pro Arg Thr Met Thr Thr Leu Ser Thr 490 495 500 cat gac acc aaa cgt ggc gaa gat acc cgc gcc cgc atc atc tcc ctg 1651 His Asp Thr Lys Arg Gly Glu Asp Thr Arg Ala Arg Ile Ile Ser Leu 505 510 515 tct gaa gtc ccc gat atg tac tcc gag ctg gtc aat cgt gtt ttc gcg 1699 Ser Glu Val Pro Asp Met Tyr Ser Glu Leu Val Asn Arg Val Phe Ala 520 525 530 gtg ctc ccc gcg cca gac ggc gca acg ggc agt ttc ctc cta caa aac 1747 Val Leu Pro Ala Pro Asp Gly Ala Thr Gly Ser Phe Leu Leu Gln Asn 535 540 545 ctg ctg ggc gta tgg ccc gcc gac ggc gtg atc acc gat gcg ctg cgc 1795 Leu Leu Gly Val Trp Pro Ala Asp Gly Val Ile Thr Asp Ala Leu Arg 550 555 560 565 gat cga ttc agg gaa tac gcc cta aaa gct atc cgc gaa gca tcc aca 1843 Asp Arg Phe Arg Glu Tyr Ala Leu Lys Ala Ile Arg Glu Ala Ser Thr 570 575 580 aaa acc acg tgg gtg gac ccc aac gag tcc ttc gag gct gcg gtc tgc 1891 Lys Thr Thr Trp Val Asp Pro Asn Glu Ser Phe Glu Ala Ala Val Cys 585 590 595 gat tgg gtg gaa gcg ctt ttc gac gga ccc tcc acc tca cta atc acc 1939 Asp Trp Val Glu Ala Leu Phe Asp Gly Pro Ser Thr Ser Leu Ile Thr 600 605 610 gaa ttt gtc tcc cac atc aac cgt ggc tct gtg caa atc tcc tta ggc 1987 Glu Phe Val Ser His Ile Asn Arg Gly Ser Val Gln Ile Ser Leu Gly 615 620 625 agg aaa ctg ctg caa atg gtg ggc gct gga atc ccc gac act tac caa 2035 Arg Lys Leu Leu Gln Met Val Gly Ala Gly Ile Pro Asp Thr Tyr Gln 630 635 640 645 gga act gag ttt tta gaa gac tcc ctg gta gat ccc gat aac cga cgc 2083 Gly Thr Glu Phe Leu Glu Asp Ser Leu Val Asp Pro Asp Asn Arg Arg 650 655 660 ttt gtt gat tac acc gcc aga gaa caa gtc ctg gag cgc ctg caa acc 2131 Phe Val Asp Tyr Thr Ala Arg Glu Gln Val Leu Glu Arg Leu Gln Thr 665 670 675 tgg gat tgg acg cag gtt aat tcg gta gaa gac ttg gtg gat aac gcc 2179 Trp Asp Trp Thr Gln Val Asn Ser Val Glu Asp Leu Val Asp Asn Ala 680 685 690 gac atc gcc aaa atg gcc gtg gtc cat aaa tcc ctc gag ttg cgt gct 2227 Asp Ile Ala Lys Met Ala Val Val His Lys Ser Leu Glu Leu Arg Ala 695 700 705 gaa ttt cgt gca agc ttt gtt ggt gga gat cat cag gca gta ttt ggc 2275 Glu Phe Arg Ala Ser Phe Val Gly Gly Asp His Gln Ala Val Phe Gly 710 715 720 725 gaa ggt cgc gca gaa tcc cac atc atg ggc atc gcc cgc ggt aca gac 2323 Glu Gly Arg Ala Glu Ser His Ile Met Gly Ile Ala Arg Gly Thr Asp 730 735 740 cga aac cac ctc aac atc att gct ctt gct acc cgt cga cca ctg atc 2371 Arg Asn His Leu Asn Ile Ile Ala Leu Ala Thr Arg Arg Pro Leu Ile 745 750 755 ttg gaa gac cgt ggc gga tgg tat gac acc acc gtc acg ctt cct ggt 2419 Leu Glu Asp Arg Gly Gly Trp Tyr Asp Thr Thr Val Thr Leu Pro Gly 760 765 770 gga caa tgg gaa gac agg ctc acc ggg caa cgc ttc agt ggt gtt gtc 2467 Gly Gln Trp Glu Asp Arg Leu Thr Gly Gln Arg Phe Ser Gly Val Val 775 780 785 cca gcc acc gat ttg ttc tca cat cta ccc gta tct ttg ttg gtt tta 2515 Pro Ala Thr Asp Leu Phe Ser His Leu Pro Val Ser Leu Leu Val Leu 790 795 800 805 gta ccc gat agt gag ttt tgatccctgc acaggaaagt tag 2556 Val Pro Asp Ser Glu Phe 810 <210> 1144 <211> 811 <212> PRT <213> Corynebacterium glutamicum <400> 1144 Met Ala Arg Pro Ile Ser Ala Thr Tyr Arg Leu Gln Met Arg Gly Pro 1 5 10 15 Gln Ala Asp Ser Ala Gly Arg Ser Phe Gly Phe Ala Gln Ala Lys Ala 20 25 30 Gln Leu Pro Tyr Leu Lys Lys Leu Gly Ile Ser His Leu Tyr Leu Ser 35 40 45 Pro Ile Phe Thr Ala Met Pro Asp Ser Asn His Gly Tyr Asp Val Ile 50 55 60 Asp Pro Thr Thr Ile Asn Glu Glu Leu Gly Gly Met Glu Gly Leu Arg 65 70 75 80 Asp Leu Ala Ala Ala Thr His Glu Leu Gly Met Gly Ile Ile Ile Asp 85 90 95 Ile Val Pro Asn His Leu Gly Val Ala Val Pro His Leu Asn Pro Trp 100 105 110 Trp Trp Asp Val Leu Lys Asn Gly Lys Asp Ser Ala Phe Glu Phe Tyr 115 120 125 Phe Asp Ile Asp Trp His Glu Asp Asn Gly Ser Gly Gly Lys Leu Gly 130 135 140 Met Pro Ile Leu Gly Ala Glu Gly Asp Glu Asp Lys Leu Glu Phe Ala 145 150 155 160 Glu Leu Asp Gly Glu Lys Val Leu Lys Tyr Phe Asp His Leu Phe Pro 165 170 175 Ile Ala Pro Gly Thr Glu Glu Gly Thr Pro Gln Glu Val Tyr Lys Arg 180 185 190 Gln His Tyr Arg Leu Gln Phe Trp Arg Asp Gly Val Ile Asn Phe Arg 195 200 205 Arg Phe Phe Ser Val Asn Thr Leu Ala Gly Ile Arg Gln Glu Asp Pro 210 215 220 Leu Val Phe Glu His Thr His Arg Leu Leu Arg Glu Leu Val Ala Glu 225 230 235 240 Asp Leu Ile Asp Gly Val Arg Val Asp His Pro Asp Gly Leu Ser Asp 245 250 255 Pro Phe Gly Tyr Leu His Arg Leu Arg Asp Leu Ile Gly Pro Asp Arg 260 265 270 Trp Leu Ile Ile Glu Lys Ile Leu Ser Val Asp Glu Pro Leu Asp Pro 275 280 285 Arg Leu Ala Val Asp Gly Thr Thr Gly Tyr Asp Ala Leu Arg Glu Leu 290 295 300 Asp Gly Val Phe Ile Ser Arg Glu Ser Glu Asp Lys Phe Ser Met Leu 305 310 315 320 Ala Leu Thr His Ser Gly Ser Thr Trp Asp Glu Arg Ala Leu Lys Ser 325 330 335 Thr Glu Glu Ser Leu Lys Arg Val Val Ala Gln Gln Glu Leu Ala Ala 340 345 350 Glu Ile Leu Arg Leu Ala Arg Ala Met Arg Arg Asp Asn Phe Ser Thr 355 360 365 Ala Gly Thr Asn Val Thr Glu Asp Lys Leu Ser Glu Thr Ile Ile Glu 370 375 380 Leu Val Ala Ala Met Pro Val Tyr Arg Ala Asp Tyr Ile Ser Leu Ser 385 390 395 400 Arg Thr Thr Ala Thr Val Ile Ala Glu Met Ser Lys Arg Phe Pro Ser 405 410 415 Arg Arg Asp Ala Leu Asp Leu Ile Ala Ala Ala Leu Leu Gly Asn Gly 420 425 430 Glu Ala Lys Ile Arg Phe Ala Gln Val Cys Gly Ala Val Met Ala Lys 435 440 445 Gly Val Glu Asp Thr Thr Phe Tyr Arg Ala Ser Arg Leu Val Ala Leu 450 455 460 Gln Glu Val Gly Gly Ala Pro Gly Arg Phe Gly Val Ser Ala Ala Glu 465 470 475 480 Phe His Leu Leu Gln Glu Glu Arg Ser Leu Leu Trp Pro Arg Thr Met 485 490 495 Thr Thr Leu Ser Thr His Asp Thr Lys Arg Gly Glu Asp Thr Arg Ala 500 505 510 Arg Ile Ile Ser Leu Ser Glu Val Pro Asp Met Tyr Ser Glu Leu Val 515 520 525 Asn Arg Val Phe Ala Val Leu Pro Ala Pro Asp Gly Ala Thr Gly Ser 530 535 540 Phe Leu Leu Gln Asn Leu Leu Gly Val Trp Pro Ala Asp Gly Val Ile 545 550 555 560 Thr Asp Ala Leu Arg Asp Arg Phe Arg Glu Tyr Ala Leu Lys Ala Ile 565 570 575 Arg Glu Ala Ser Thr Lys Thr Thr Trp Val Asp Pro Asn Glu Ser Phe 580 585 590 Glu Ala Ala Val Cys Asp Trp Val Glu Ala Leu Phe Asp Gly Pro Ser 595 600 605 Thr Ser Leu Ile Thr Glu Phe Val Ser His Ile Asn Arg Gly Ser Val 610 615 620 Gln Ile Ser Leu Gly Arg Lys Leu Leu Gln Met Val Gly Ala Gly Ile 625 630 635 640 Pro Asp Thr Tyr Gln Gly Thr Glu Phe Leu Glu Asp Ser Leu Val Asp 645 650 655 Pro Asp Asn Arg Arg Phe Val Asp Tyr Thr Ala Arg Glu Gln Val Leu 660 665 670 Glu Arg Leu Gln Thr Trp Asp Trp Thr Gln Val Asn Ser Val Glu Asp 675 680 685 Leu Val Asp Asn Ala Asp Ile Ala Lys Met Ala Val Val His Lys Ser 690 695 700 Leu Glu Leu Arg Ala Glu Phe Arg Ala Ser Phe Val Gly Gly Asp His 705 710 715 720 Gln Ala Val Phe Gly Glu Gly Arg Ala Glu Ser His Ile Met Gly Ile 725 730 735 Ala Arg Gly Thr Asp Arg Asn His Leu Asn Ile Ile Ala Leu Ala Thr 740 745 750 Arg Arg Pro Leu Ile Leu Glu Asp Arg Gly Gly Trp Tyr Asp Thr Thr 755 760 765 Val Thr Leu Pro Gly Gly Gln Trp Glu Asp Arg Leu Thr Gly Gln Arg 770 775 780 Phe Ser Gly Val Val Pro Ala Thr Asp Leu Phe Ser His Leu Pro Val 785 790 795 800 Ser Leu Leu Val Leu Val Pro Asp Ser Glu Phe 805 810 <210> 1145 <211> 1953 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1930) <223> RXA02645 <400> 1145 gatacagctc cttgatggag tgaataaatt cgcgagcctg ctcctgatct tgcacacgcg 60 tgatataggt cagaaatcgc gagcgcttga tctctagttc atg ctc aaa gac ttg 115 Met Leu Lys Asp Leu 1 5 acc ggc ctg agg gag ttg gta ttg cgt gag atg tgc cat agc atc tca 163 Thr Gly Leu Arg Glu Leu Val Leu Arg Glu Met Cys His Ser Ile Ser 10 15 20 cat ctt agc tcg cca acc ggc agc att ttc act agc ctg gtg gcc atg 211 His Leu Ser Ser Pro Thr Gly Ser Ile Phe Thr Ser Leu Val Ala Met 25 30 35 ttg acc tcg caa agc ttt tca gtg tgg gct cca ctt ccc cac gat gta 259 Leu Thr Ser Gln Ser Phe Ser Val Trp Ala Pro Leu Pro His Asp Val 40 45 50 cat ctg atc ctc aac ggc gaa acc ctc ccc atg cac aaa acg gag ggc 307 His Leu Ile Leu Asn Gly Glu Thr Leu Pro Met His Lys Thr Glu Gly 55 60 65 agc tgg tgg cgc gcc gag atc gcg ccc aag gcc ggc gat cgt tac ggt 355 Ser Trp Trp Arg Ala Glu Ile Ala Pro Lys Ala Gly Asp Arg Tyr Gly 70 75 80 85 ttt tcg ctt ttc gac ggc tcc tcc tgg tca aaa acc ctc ccc gat ccc 403 Phe Ser Leu Phe Asp Gly Ser Ser Trp Ser Lys Thr Leu Pro Asp Pro 90 95 100 cgc tcc aca tct caa cca gac ggg gtt cat ggt tta agt gaa gtc tcc 451 Arg Ser Thr Ser Gln Pro Asp Gly Val His Gly Leu Ser Glu Val Ser 105 110 115 gat gat tcc tat ctg tgg ggt gac cag cag tgg act ggc cga att ctc 499 Asp Asp Ser Tyr Leu Trp Gly Asp Gln Gln Trp Thr Gly Arg Ile Leu 120 125 130 cct ggc tcg gtg tta tat gag ctg cat gtg ggc acc ttt agt gaa gat 547 Pro Gly Ser Val Leu Tyr Glu Leu His Val Gly Thr Phe Ser Glu Asp 135 140 145 gga acg ttt gag gga gtc gtc gac aag ctt cct tat ctg cgc gac ctc 595 Gly Thr Phe Glu Gly Val Val Asp Lys Leu Pro Tyr Leu Arg Asp Leu 150 155 160 165 ggc gtg acc gcc atc gaa ctt tta ccc gtg cag ccc ttt ggc ggc aac 643 Gly Val Thr Ala Ile Glu Leu Leu Pro Val Gln Pro Phe Gly Gly Asn 170 175 180 cgc aat tgg ggc tac gac ggg gtg ctg tgg cac gcc gtc cat gca ggc 691 Arg Asn Trp Gly Tyr Asp Gly Val Leu Trp His Ala Val His Ala Gly 185 190 195 tac ggc ggt ccg gcg ggc ttg aaa aag ctt atc gac gcc tcc cac cag 739 Tyr Gly Gly Pro Ala Gly Leu Lys Lys Leu Ile Asp Ala Ser His Gln 200 205 210 gcc ggc atc gcc gtc tac tta gac gtc gtg tac aac cac ttc ggc ccc 787 Ala Gly Ile Ala Val Tyr Leu Asp Val Val Tyr Asn His Phe Gly Pro 215 220 225 gac ggc aac tac aac ggg caa ttt ggc ccc tac acc tct ggc ggc agc 835 Asp Gly Asn Tyr Asn Gly Gln Phe Gly Pro Tyr Thr Ser Gly Gly Ser 230 235 240 245 acc ggc tgg ggc gac gtg gtc aac atc aac ggc cat gat tca gat gaa 883 Thr Gly Trp Gly Asp Val Val Asn Ile Asn Gly His Asp Ser Asp Glu 250 255 260 gtc cgc aat tat att ctc gac gcc gca cgc cag tgg ttc gaa gat ttt 931 Val Arg Asn Tyr Ile Leu Asp Ala Ala Arg Gln Trp Phe Glu Asp Phe 265 270 275 cac gtt gat ggg ctc cgc ctc gat gcg gtg cat tct ctc gat gat cgc 979 His Val Asp Gly Leu Arg Leu Asp Ala Val His Ser Leu Asp Asp Arg 280 285 290 ggc gcc tat tcc cta ctt gcg cag ctg acc atg gtg gcc gag gat gtc 1027 Gly Ala Tyr Ser Leu Leu Ala Gln Leu Thr Met Val Ala Glu Asp Val 295 300 305 tcc gca caa aca ggc atc cca cgc tca ttg att gca gaa tct gaa ctc 1075 Ser Ala Gln Thr Gly Ile Pro Arg Ser Leu Ile Ala Glu Ser Glu Leu 310 315 320 325 aat gac ccc aag ttc gtt acc tcc cgc gag gcc ggc ggt ttt ggc ctg 1123 Asn Asp Pro Lys Phe Val Thr Ser Arg Glu Ala Gly Gly Phe Gly Leu 330 335 340 gat gca cag tgg gtt gac gat atc cac cac gcc ctc cat gcc ctc gtt 1171 Asp Ala Gln Trp Val Asp Asp Ile His His Ala Leu His Ala Leu Val 345 350 355 tct ggc gaa cgc aat ggt tat tac agc gat ttc gga tct gtc gac aca 1219 Ser Gly Glu Arg Asn Gly Tyr Tyr Ser Asp Phe Gly Ser Val Asp Thr 360 365 370 tta gcc aaa acc ctg cgt gaa gta ttt gaa cac acc gga aac tac tcc 1267 Leu Ala Lys Thr Leu Arg Glu Val Phe Glu His Thr Gly Asn Tyr Ser 375 380 385 acg tac cgc gga cgc aac cac ggc cgc cct gtg cac ccc gat atc acc 1315 Thr Tyr Arg Gly Arg Asn His Gly Arg Pro Val His Pro Asp Ile Thr 390 395 400 405 cct gcc tcg cgc ttt gtc acc tac acc acc acc cat gat cag acc ggc 1363 Pro Ala Ser Arg Phe Val Thr Tyr Thr Thr Thr His Asp Gln Thr Gly 410 415 420 aac cgc gca atc ggc gac cgt cct tcc acg act ctc acc ccg gaa cag 1411 Asn Arg Ala Ile Gly Asp Arg Pro Ser Thr Thr Leu Thr Pro Glu Gln 425 430 435 cag gtg ttg aag gca gcc att atc tac agc tcg ccg tat acc ccg atg 1459 Gln Val Leu Lys Ala Ala Ile Ile Tyr Ser Ser Pro Tyr Thr Pro Met 440 445 450 ttg ttt atg ggt gaa gaa ttc gga gcc acc acc cca ttc gcc ttc ttt 1507 Leu Phe Met Gly Glu Glu Phe Gly Ala Thr Thr Pro Phe Ala Phe Phe 455 460 465 tgc tcc cac acc gac ccc gag ctc aac cgg cta acc tcc gag ggc cgc 1555 Cys Ser His Thr Asp Pro Glu Leu Asn Arg Leu Thr Ser Glu Gly Arg 470 475 480 485 aaa cgg gaa ttc gca cgc ctt ggc tgg aac gcc gac gac atc ccc tcc 1603 Lys Arg Glu Phe Ala Arg Leu Gly Trp Asn Ala Asp Asp Ile Pro Ser 490 495 500 ccc gag ctg gaa tcc acc ttc acc tcc tcc aaa ctc gat tgg gag ttc 1651 Pro Glu Leu Glu Ser Thr Phe Thr Ser Ser Lys Leu Asp Trp Glu Phe 505 510 515 act gcg gag cag cgc cgc atc aac gac gct tac aag cag ctg ttg cac 1699 Thr Ala Glu Gln Arg Arg Ile Asn Asp Ala Tyr Lys Gln Leu Leu His 520 525 530 ctg cgg cac acc ttg ggc ttc tcc caa cca aac ttg ctc aca ctc gag 1747 Leu Arg His Thr Leu Gly Phe Ser Gln Pro Asn Leu Leu Thr Leu Glu 535 540 545 gtt gag cac ggc gag aac tgg cta tcg atg gcc aat ggt cgc ggc cga 1795 Val Glu His Gly Glu Asn Trp Leu Ser Met Ala Asn Gly Arg Gly Arg 550 555 560 565 att ctg gcg aat ttc tcc gac gac acc atc acc gtc ccg ctt ggc ggc 1843 Ile Leu Ala Asn Phe Ser Asp Asp Thr Ile Thr Val Pro Leu Gly Gly 570 575 580 gag ctg att tac agc ttc act tcc ccc acc gtc acc gac acc tcc aca 1891 Glu Leu Ile Tyr Ser Phe Thr Ser Pro Thr Val Thr Asp Thr Ser Thr 585 590 595 acc ctt cag ccg tgg ggc ttt gcg atc ctg acc cga aac tagaaaaagg 1940 Thr Leu Gln Pro Trp Gly Phe Ala Ile Leu Thr Arg Asn 600 605 610 ccacctcgat tga 1953 <210> 1146 <211> 610 <212> PRT <213> Corynebacterium glutamicum <400> 1146 Met Leu Lys Asp Leu Thr Gly Leu Arg Glu Leu Val Leu Arg Glu Met 1 5 10 15 Cys His Ser Ile Ser His Leu Ser Ser Pro Thr Gly Ser Ile Phe Thr 20 25 30 Ser Leu Val Ala Met Leu Thr Ser Gln Ser Phe Ser Val Trp Ala Pro 35 40 45 Leu Pro His Asp Val His Leu Ile Leu Asn Gly Glu Thr Leu Pro Met 50 55 60 His Lys Thr Glu Gly Ser Trp Trp Arg Ala Glu Ile Ala Pro Lys Ala 65 70 75 80 Gly Asp Arg Tyr Gly Phe Ser Leu Phe Asp Gly Ser Ser Trp Ser Lys 85 90 95 Thr Leu Pro Asp Pro Arg Ser Thr Ser Gln Pro Asp Gly Val His Gly 100 105 110 Leu Ser Glu Val Ser Asp Asp Ser Tyr Leu Trp Gly Asp Gln Gln Trp 115 120 125 Thr Gly Arg Ile Leu Pro Gly Ser Val Leu Tyr Glu Leu His Val Gly 130 135 140 Thr Phe Ser Glu Asp Gly Thr Phe Glu Gly Val Val Asp Lys Leu Pro 145 150 155 160 Tyr Leu Arg Asp Leu Gly Val Thr Ala Ile Glu Leu Leu Pro Val Gln 165 170 175 Pro Phe Gly Gly Asn Arg Asn Trp Gly Tyr Asp Gly Val Leu Trp His 180 185 190 Ala Val His Ala Gly Tyr Gly Gly Pro Ala Gly Leu Lys Lys Leu Ile 195 200 205 Asp Ala Ser His Gln Ala Gly Ile Ala Val Tyr Leu Asp Val Val Tyr 210 215 220 Asn His Phe Gly Pro Asp Gly Asn Tyr Asn Gly Gln Phe Gly Pro Tyr 225 230 235 240 Thr Ser Gly Gly Ser Thr Gly Trp Gly Asp Val Val Asn Ile Asn Gly 245 250 255 His Asp Ser Asp Glu Val Arg Asn Tyr Ile Leu Asp Ala Ala Arg Gln 260 265 270 Trp Phe Glu Asp Phe His Val Asp Gly Leu Arg Leu Asp Ala Val His 275 280 285 Ser Leu Asp Asp Arg Gly Ala Tyr Ser Leu Leu Ala Gln Leu Thr Met 290 295 300 Val Ala Glu Asp Val Ser Ala Gln Thr Gly Ile Pro Arg Ser Leu Ile 305 310 315 320 Ala Glu Ser Glu Leu Asn Asp Pro Lys Phe Val Thr Ser Arg Glu Ala 325 330 335 Gly Gly Phe Gly Leu Asp Ala Gln Trp Val Asp Asp Ile His His Ala 340 345 350 Leu His Ala Leu Val Ser Gly Glu Arg Asn Gly Tyr Tyr Ser Asp Phe 355 360 365 Gly Ser Val Asp Thr Leu Ala Lys Thr Leu Arg Glu Val Phe Glu His 370 375 380 Thr Gly Asn Tyr Ser Thr Tyr Arg Gly Arg Asn His Gly Arg Pro Val 385 390 395 400 His Pro Asp Ile Thr Pro Ala Ser Arg Phe Val Thr Tyr Thr Thr Thr 405 410 415 His Asp Gln Thr Gly Asn Arg Ala Ile Gly Asp Arg Pro Ser Thr Thr 420 425 430 Leu Thr Pro Glu Gln Gln Val Leu Lys Ala Ala Ile Ile Tyr Ser Ser 435 440 445 Pro Tyr Thr Pro Met Leu Phe Met Gly Glu Glu Phe Gly Ala Thr Thr 450 455 460 Pro Phe Ala Phe Phe Cys Ser His Thr Asp Pro Glu Leu Asn Arg Leu 465 470 475 480 Thr Ser Glu Gly Arg Lys Arg Glu Phe Ala Arg Leu Gly Trp Asn Ala 485 490 495 Asp Asp Ile Pro Ser Pro Glu Leu Glu Ser Thr Phe Thr Ser Ser Lys 500 505 510 Leu Asp Trp Glu Phe Thr Ala Glu Gln Arg Arg Ile Asn Asp Ala Tyr 515 520 525 Lys Gln Leu Leu His Leu Arg His Thr Leu Gly Phe Ser Gln Pro Asn 530 535 540 Leu Leu Thr Leu Glu Val Glu His Gly Glu Asn Trp Leu Ser Met Ala 545 550 555 560 Asn Gly Arg Gly Arg Ile Leu Ala Asn Phe Ser Asp Asp Thr Ile Thr 565 570 575 Val Pro Leu Gly Gly Glu Leu Ile Tyr Ser Phe Thr Ser Pro Thr Val 580 585 590 Thr Asp Thr Ser Thr Thr Leu Gln Pro Trp Gly Phe Ala Ile Leu Thr 595 600 605 Arg Asn 610 <210> 1147 <211> 832 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(832) <223> RXN02355 <400> 1147 atttttgacc ctccgggggt gatttaacct aaaattccac acaaacgtgt tcgaggtcat 60 tagattgata agcatctgtt gttaagaaag gtgacttcct atg tcc tcg att tcc 115 Met Ser Ser Ile Ser 1 5 cgc aag acc ggc gcg tca ctt gca gcc acc aca ctg ttg gca gcg atc 163 Arg Lys Thr Gly Ala Ser Leu Ala Ala Thr Thr Leu Leu Ala Ala Ile 10 15 20 gca ctg gcc ggt tgt agt tca gac tca agc tcc gac tcc aca gat tcc 211 Ala Leu Ala Gly Cys Ser Ser Asp Ser Ser Ser Asp Ser Thr Asp Ser 25 30 35 acc gct agc gaa ggc gca gac agc cgc ggc ccc atc acc ttt gcg atg 259 Thr Ala Ser Glu Gly Ala Asp Ser Arg Gly Pro Ile Thr Phe Ala Met 40 45 50 ggc aaa aac gac acc gac aaa gtc att ccg atc atc gac cgc tgg aac 307 Gly Lys Asn Asp Thr Asp Lys Val Ile Pro Ile Ile Asp Arg Trp Asn 55 60 65 gaa gcc cac ccc gat gag cag gta acg ctc aac gaa ctc gcc ggt gaa 355 Glu Ala His Pro Asp Glu Gln Val Thr Leu Asn Glu Leu Ala Gly Glu 70 75 80 85 gcc gac gcg cag cgc gaa acc ctc gtg caa tcc ctg cag gcc ggc aac 403 Ala Asp Ala Gln Arg Glu Thr Leu Val Gln Ser Leu Gln Ala Gly Asn 90 95 100 tct gac tac gac gtc atg gcg ctc gac gtc atc tgg acc gca gac ttc 451 Ser Asp Tyr Asp Val Met Ala Leu Asp Val Ile Trp Thr Ala Asp Phe 105 110 115 gcg gca aac caa tgg ctc gca cca ctt gaa ggc gac ctc gag gta gac 499 Ala Ala Asn Gln Trp Leu Ala Pro Leu Glu Gly Asp Leu Glu Val Asp 120 125 130 acc tcc gga ctg ctg caa tcc acc gtg gat tcc gca acc tac aac ggc 547 Thr Ser Gly Leu Leu Gln Ser Thr Val Asp Ser Ala Thr Tyr Asn Gly 135 140 145 acc ctc tac gca ctg cca cag aac acc aac ggc cag cta ctg ttc cgc 595 Thr Leu Tyr Ala Leu Pro Gln Asn Thr Asn Gly Gln Leu Leu Phe Arg 150 155 160 165 aac acc gaa atc atc cca gaa gca cca gca aac tgg gct gac ctc gtg 643 Asn Thr Glu Ile Ile Pro Glu Ala Pro Ala Asn Trp Ala Asp Leu Val 170 175 180 gaa tcc tgc acg ctt gct gaa gaa gca ggc gtt gat tgc ctg acc act 691 Glu Ser Cys Thr Leu Ala Glu Glu Ala Gly Val Asp Cys Leu Thr Thr 185 190 195 cag ctc aag cag tac gaa ggc ctt tca gtg aac acc atc ggc ttc atc 739 Gln Leu Lys Gln Tyr Glu Gly Leu Ser Val Asn Thr Ile Gly Phe Ile 200 205 210 gaa ggt tgg gga ggc agc gtc cta gac gat gac ggc aaa cgt cac cgt 787 Glu Gly Trp Gly Gly Ser Val Leu Asp Asp Asp Gly Lys Arg His Arg 215 220 225 aga cag cac gac ggc aag gca ggc ctt caa gcg ctt gtc gac ggc 832 Arg Gln His Asp Gly Lys Ala Gly Leu Gln Ala Leu Val Asp Gly 230 235 240 <210> 1148 <211> 244 <212> PRT <213> Corynebacterium glutamicum <400> 1148 Met Ser Ser Ile Ser Arg Lys Thr Gly Ala Ser Leu Ala Ala Thr Thr 1 5 10 15 Leu Leu Ala Ala Ile Ala Leu Ala Gly Cys Ser Ser Asp Ser Ser Ser 20 25 30 Asp Ser Thr Asp Ser Thr Ala Ser Glu Gly Ala Asp Ser Arg Gly Pro 35 40 45 Ile Thr Phe Ala Met Gly Lys Asn Asp Thr Asp Lys Val Ile Pro Ile 50 55 60 Ile Asp Arg Trp Asn Glu Ala His Pro Asp Glu Gln Val Thr Leu Asn 65 70 75 80 Glu Leu Ala Gly Glu Ala Asp Ala Gln Arg Glu Thr Leu Val Gln Ser 85 90 95 Leu Gln Ala Gly Asn Ser Asp Tyr Asp Val Met Ala Leu Asp Val Ile 100 105 110 Trp Thr Ala Asp Phe Ala Ala Asn Gln Trp Leu Ala Pro Leu Glu Gly 115 120 125 Asp Leu Glu Val Asp Thr Ser Gly Leu Leu Gln Ser Thr Val Asp Ser 130 135 140 Ala Thr Tyr Asn Gly Thr Leu Tyr Ala Leu Pro Gln Asn Thr Asn Gly 145 150 155 160 Gln Leu Leu Phe Arg Asn Thr Glu Ile Ile Pro Glu Ala Pro Ala Asn 165 170 175 Trp Ala Asp Leu Val Glu Ser Cys Thr Leu Ala Glu Glu Ala Gly Val 180 185 190 Asp Cys Leu Thr Thr Gln Leu Lys Gln Tyr Glu Gly Leu Ser Val Asn 195 200 205 Thr Ile Gly Phe Ile Glu Gly Trp Gly Gly Ser Val Leu Asp Asp Asp 210 215 220 Gly Lys Arg His Arg Arg Gln His Asp Gly Lys Ala Gly Leu Gln Ala 225 230 235 240 Leu Val Asp Gly <210> 1149 <211> 609 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(586) <223> RXN02909 <400> 1149 caacgcgaat gaaaacgaac agcgagcagg tctataccca cgacgtcaac gtgtgggcta 60 atagtttcct ggattgtttg gcacagtcgg gagaaaactc atg aac cgc gca cga 115 Met Asn Arg Ala Arg 1 5 atc gcg acc ata ggc gtt ctt ccg ctt gct tta ctg ctg gcg tcc tgt 163 Ile Ala Thr Ile Gly Val Leu Pro Leu Ala Leu Leu Leu Ala Ser Cys 10 15 20 ggt tca gac acc gtg gaa atg aca gat tcc acc tgg ttg gtg acc aat 211 Gly Ser Asp Thr Val Glu Met Thr Asp Ser Thr Trp Leu Val Thr Asn 25 30 35 att tac acc gat cca gat gag tcg aat tcg atc agt aat ctt gtc att 259 Ile Tyr Thr Asp Pro Asp Glu Ser Asn Ser Ile Ser Asn Leu Val Ile 40 45 50 tcc cag ccc agc tta gat ttt ggc aat tct tcc ctg tct ggt ttc act 307 Ser Gln Pro Ser Leu Asp Phe Gly Asn Ser Ser Leu Ser Gly Phe Thr 55 60 65 ggc tgt gtg cct ttt acg ggg cgt gcg gaa ttc ttc caa aat ggt gag 355 Gly Cys Val Pro Phe Thr Gly Arg Ala Glu Phe Phe Gln Asn Gly Glu 70 75 80 85 caa agc tct gtt ctg gat gcc gat tat gtg acc ttg tct tcc ctg gat 403 Gln Ser Ser Val Leu Asp Ala Asp Tyr Val Thr Leu Ser Ser Leu Asp 90 95 100 ttc gat aaa ctt ccc gat gat tgc caa gga caa gaa ctc aaa gtt cat 451 Phe Asp Lys Leu Pro Asp Asp Cys Gln Gly Gln Glu Leu Lys Val His 105 110 115 aac gag ctg gtt gat ctt ctg cct ggt tct ttt gaa atc tcc agg act 499 Asn Glu Leu Val Asp Leu Leu Pro Gly Ser Phe Glu Ile Ser Arg Thr 120 125 130 tct ggt tca gaa atc ttg ctg act agc gat gtc gat gaa ctc gat cgg 547 Ser Gly Ser Glu Ile Leu Leu Thr Ser Asp Val Asp Glu Leu Asp Arg 135 140 145 cca gca atc cgc ttg gtg tcc tgg atc gcg ccg aca tct taaggtgcca 596 Pro Ala Ile Arg Leu Val Ser Trp Ile Ala Pro Thr Ser 150 155 160 gggctttaaa gtg 609 <210> 1150 <211> 162 <212> PRT <213> Corynebacterium glutamicum <400> 1150 Met Asn Arg Ala Arg Ile Ala Thr Ile Gly Val Leu Pro Leu Ala Leu 1 5 10 15 Leu Leu Ala Ser Cys Gly Ser Asp Thr Val Glu Met Thr Asp Ser Thr 20 25 30 Trp Leu Val Thr Asn Ile Tyr Thr Asp Pro Asp Glu Ser Asn Ser Ile 35 40 45 Ser Asn Leu Val Ile Ser Gln Pro Ser Leu Asp Phe Gly Asn Ser Ser 50 55 60 Leu Ser Gly Phe Thr Gly Cys Val Pro Phe Thr Gly Arg Ala Glu Phe 65 70 75 80 Phe Gln Asn Gly Glu Gln Ser Ser Val Leu Asp Ala Asp Tyr Val Thr 85 90 95 Leu Ser Ser Leu Asp Phe Asp Lys Leu Pro Asp Asp Cys Gln Gly Gln 100 105 110 Glu Leu Lys Val His Asn Glu Leu Val Asp Leu Leu Pro Gly Ser Phe 115 120 125 Glu Ile Ser Arg Thr Ser Gly Ser Glu Ile Leu Leu Thr Ser Asp Val 130 135 140 Asp Glu Leu Asp Arg Pro Ala Ile Arg Leu Val Ser Trp Ile Ala Pro 145 150 155 160 Thr Ser <210> 1151 <211> 1590 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1567) <223> RXS00349 <400> 1151 tgtgtacatc acaatggaat tcggggctag agtatctggt gaaccgtgca taaacgacct 60 gtgattggac tctttttcct tgcaaaatgt tttccagcgg atg ttg agt ttt gcg 115 Met Leu Ser Phe Ala 1 5 acc ctt cgt ggc cgc att tca aca gtt gac gct gca aaa gcc gca cct 163 Thr Leu Arg Gly Arg Ile Ser Thr Val Asp Ala Ala Lys Ala Ala Pro 10 15 20 ccg cca tcg cca cta gcc ccg att gat ctc act gac cat agt caa gtg 211 Pro Pro Ser Pro Leu Ala Pro Ile Asp Leu Thr Asp His Ser Gln Val 25 30 35 gcc ggt gtg atg aat ttg gct gcg aga att ggc gat att ttg ctt tct 259 Ala Gly Val Met Asn Leu Ala Ala Arg Ile Gly Asp Ile Leu Leu Ser 40 45 50 tca ggt acg tca aat agt gac acc aag gta caa gtt cga gca gtg acc 307 Ser Gly Thr Ser Asn Ser Asp Thr Lys Val Gln Val Arg Ala Val Thr 55 60 65 tct gcg tac ggt ttg tac tac acg cac gtg gat atc acg ttg aat acg 355 Ser Ala Tyr Gly Leu Tyr Tyr Thr His Val Asp Ile Thr Leu Asn Thr 70 75 80 85 atc acc atc ttc acc aac atc ggt gtg gag agg aag atg ccg gtc aac 403 Ile Thr Ile Phe Thr Asn Ile Gly Val Glu Arg Lys Met Pro Val Asn 90 95 100 gtg ttt cat gtt gta ggc aag ttg gac acc aac ttc tcc aaa ctg tct 451 Val Phe His Val Val Gly Lys Leu Asp Thr Asn Phe Ser Lys Leu Ser 105 110 115 gag gtt gac cgt ttg atc cgt tcc att cag gct ggt gcg acc ccg cct 499 Glu Val Asp Arg Leu Ile Arg Ser Ile Gln Ala Gly Ala Thr Pro Pro 120 125 130 gag gtt gcc gag aaa atc ctg gac gag ttg gag caa tcc cct gcg tct 547 Glu Val Ala Glu Lys Ile Leu Asp Glu Leu Glu Gln Ser Pro Ala Ser 135 140 145 tat ggt ttc cct gtt gcg ttg ctt ggc tgg gca atg atg ggt ggt gct 595 Tyr Gly Phe Pro Val Ala Leu Leu Gly Trp Ala Met Met Gly Gly Ala 150 155 160 165 gtt gct gtg ctg ttg ggt ggt gga tgg cag gtt tcc cta att gct ttt 643 Val Ala Val Leu Leu Gly Gly Gly Trp Gln Val Ser Leu Ile Ala Phe 170 175 180 att acc gcg ttc acg atc att gcc acg acg tca ttt ttg gga aag aag 691 Ile Thr Ala Phe Thr Ile Ile Ala Thr Thr Ser Phe Leu Gly Lys Lys 185 190 195 ggt ttg cct act ttc ttc caa aat gtt gtt ggt ggt ttt att gcc acg 739 Gly Leu Pro Thr Phe Phe Gln Asn Val Val Gly Gly Phe Ile Ala Thr 200 205 210 ctg cct gca tcg att gct tat tct ttg gcg ttg caa ttt ggt ctt gag 787 Leu Pro Ala Ser Ile Ala Tyr Ser Leu Ala Leu Gln Phe Gly Leu Glu 215 220 225 atc aaa ccg agc cag atc atc gca tct gga att gtt gtg ctg ttg gca 835 Ile Lys Pro Ser Gln Ile Ile Ala Ser Gly Ile Val Val Leu Leu Ala 230 235 240 245 ggt ttg aca ctc gtg caa tct ctg cag gac ggc atc acg ggc gct ccg 883 Gly Leu Thr Leu Val Gln Ser Leu Gln Asp Gly Ile Thr Gly Ala Pro 250 255 260 gtg aca gca agt gca cga ttt ttc gaa aca ctc ctg ttt acc ggc ggc 931 Val Thr Ala Ser Ala Arg Phe Phe Glu Thr Leu Leu Phe Thr Gly Gly 265 270 275 att gtt gct ggc gtg ggt ttg ggc att cag ctt tct gaa atc ttg cat 979 Ile Val Ala Gly Val Gly Leu Gly Ile Gln Leu Ser Glu Ile Leu His 280 285 290 gtc atg ttg cct gcc atg gag tcc gct gca gca cct aat tat tcg tct 1027 Val Met Leu Pro Ala Met Glu Ser Ala Ala Ala Pro Asn Tyr Ser Ser 295 300 305 aca ttc gcc cgc att atc gct ggt ggc gtc acc gca gcg gcc ttc gca 1075 Thr Phe Ala Arg Ile Ile Ala Gly Gly Val Thr Ala Ala Ala Phe Ala 310 315 320 325 gtg ggt tgt tac gcg gag tgg tcc tcg gtg att att gcg ggg ctt act 1123 Val Gly Cys Tyr Ala Glu Trp Ser Ser Val Ile Ile Ala Gly Leu Thr 330 335 340 gcg ctg atg ggt tct gcg ttt tat tac ctc ttc gtt gtt tat tta ggc 1171 Ala Leu Met Gly Ser Ala Phe Tyr Tyr Leu Phe Val Val Tyr Leu Gly 345 350 355 ccc gtc tct gcc gct gcg att gct gca aca gca gtt ggt ttc act ggt 1219 Pro Val Ser Ala Ala Ala Ile Ala Ala Thr Ala Val Gly Phe Thr Gly 360 365 370 ggt ttg ctt gcc cgt cga ttc ttg att cca ccg ttg att gtg gcg att 1267 Gly Leu Leu Ala Arg Arg Phe Leu Ile Pro Pro Leu Ile Val Ala Ile 375 380 385 gcc ggc atc aca cca atg ctt cca ggt cta gca att tac cgc gga atg 1315 Ala Gly Ile Thr Pro Met Leu Pro Gly Leu Ala Ile Tyr Arg Gly Met 390 395 400 405 tac gcc acc ctg aat gat caa aca ctc atg ggt ttc acc aac att gcg 1363 Tyr Ala Thr Leu Asn Asp Gln Thr Leu Met Gly Phe Thr Asn Ile Ala 410 415 420 gtt gct tta gcc act gct tca tca ctt gcc gct ggc gtg gtt ttg ggt 1411 Val Ala Leu Ala Thr Ala Ser Ser Leu Ala Ala Gly Val Val Leu Gly 425 430 435 gag tgg att gcc cgc agg cta cgt cgt cca cca cgc ttc aac cca tac 1459 Glu Trp Ile Ala Arg Arg Leu Arg Arg Pro Pro Arg Phe Asn Pro Tyr 440 445 450 cgt gca ttt acc aag gcg aat gag ttc tcc ttc cag gag gaa gct gag 1507 Arg Ala Phe Thr Lys Ala Asn Glu Phe Ser Phe Gln Glu Glu Ala Glu 455 460 465 cag aat cag cgc cgg cag aga aaa cgt cca aag act aat cag aga ttc 1555 Gln Asn Gln Arg Arg Gln Arg Lys Arg Pro Lys Thr Asn Gln Arg Phe 470 475 480 485 ggt aat aaa agg taaaaatcaa cctgcttagg cgt 1590 Gly Asn Lys Arg <210> 1152 <211> 489 <212> PRT <213> Corynebacterium glutamicum <400> 1152 Met Leu Ser Phe Ala Thr Leu Arg Gly Arg Ile Ser Thr Val Asp Ala 1 5 10 15 Ala Lys Ala Ala Pro Pro Pro Ser Pro Leu Ala Pro Ile Asp Leu Thr 20 25 30 Asp His Ser Gln Val Ala Gly Val Met Asn Leu Ala Ala Arg Ile Gly 35 40 45 Asp Ile Leu Leu Ser Ser Gly Thr Ser Asn Ser Asp Thr Lys Val Gln 50 55 60 Val Arg Ala Val Thr Ser Ala Tyr Gly Leu Tyr Tyr Thr His Val Asp 65 70 75 80 Ile Thr Leu Asn Thr Ile Thr Ile Phe Thr Asn Ile Gly Val Glu Arg 85 90 95 Lys Met Pro Val Asn Val Phe His Val Val Gly Lys Leu Asp Thr Asn 100 105 110 Phe Ser Lys Leu Ser Glu Val Asp Arg Leu Ile Arg Ser Ile Gln Ala 115 120 125 Gly Ala Thr Pro Pro Glu Val Ala Glu Lys Ile Leu Asp Glu Leu Glu 130 135 140 Gln Ser Pro Ala Ser Tyr Gly Phe Pro Val Ala Leu Leu Gly Trp Ala 145 150 155 160 Met Met Gly Gly Ala Val Ala Val Leu Leu Gly Gly Gly Trp Gln Val 165 170 175 Ser Leu Ile Ala Phe Ile Thr Ala Phe Thr Ile Ile Ala Thr Thr Ser 180 185 190 Phe Leu Gly Lys Lys Gly Leu Pro Thr Phe Phe Gln Asn Val Val Gly 195 200 205 Gly Phe Ile Ala Thr Leu Pro Ala Ser Ile Ala Tyr Ser Leu Ala Leu 210 215 220 Gln Phe Gly Leu Glu Ile Lys Pro Ser Gln Ile Ile Ala Ser Gly Ile 225 230 235 240 Val Val Leu Leu Ala Gly Leu Thr Leu Val Gln Ser Leu Gln Asp Gly 245 250 255 Ile Thr Gly Ala Pro Val Thr Ala Ser Ala Arg Phe Phe Glu Thr Leu 260 265 270 Leu Phe Thr Gly Gly Ile Val Ala Gly Val Gly Leu Gly Ile Gln Leu 275 280 285 Ser Glu Ile Leu His Val Met Leu Pro Ala Met Glu Ser Ala Ala Ala 290 295 300 Pro Asn Tyr Ser Ser Thr Phe Ala Arg Ile Ile Ala Gly Gly Val Thr 305 310 315 320 Ala Ala Ala Phe Ala Val Gly Cys Tyr Ala Glu Trp Ser Ser Val Ile 325 330 335 Ile Ala Gly Leu Thr Ala Leu Met Gly Ser Ala Phe Tyr Tyr Leu Phe 340 345 350 Val Val Tyr Leu Gly Pro Val Ser Ala Ala Ala Ile Ala Ala Thr Ala 355 360 365 Val Gly Phe Thr Gly Gly Leu Leu Ala Arg Arg Phe Leu Ile Pro Pro 370 375 380 Leu Ile Val Ala Ile Ala Gly Ile Thr Pro Met Leu Pro Gly Leu Ala 385 390 395 400 Ile Tyr Arg Gly Met Tyr Ala Thr Leu Asn Asp Gln Thr Leu Met Gly 405 410 415 Phe Thr Asn Ile Ala Val Ala Leu Ala Thr Ala Ser Ser Leu Ala Ala 420 425 430 Gly Val Val Leu Gly Glu Trp Ile Ala Arg Arg Leu Arg Arg Pro Pro 435 440 445 Arg Phe Asn Pro Tyr Arg Ala Phe Thr Lys Ala Asn Glu Phe Ser Phe 450 455 460 Gln Glu Glu Ala Glu Gln Asn Gln Arg Arg Gln Arg Lys Arg Pro Lys 465 470 475 480 Thr Asn Gln Arg Phe Gly Asn Lys Arg 485 <210> 1153 <211> 440 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (1)..(417) <223> RXS03183 <400> 1153 gaa gcc gaa gca acc gca ggc aaa ttc gaa gta cag ccc ctc gta ggt 48 Glu Ala Glu Ala Thr Ala Gly Lys Phe Glu Val Gln Pro Leu Val Gly 1 5 10 15 aaa gac ggc gtc ggc gta tcc acc ctt ggt ggc tac aac aac ggc atc 96 Lys Asp Gly Val Gly Val Ser Thr Leu Gly Gly Tyr Asn Asn Gly Ile 20 25 30 aac gtc aac tcc gaa aac aag gca acc gcc cgc gac ttc atc gaa ttc 144 Asn Val Asn Ser Glu Asn Lys Ala Thr Ala Arg Asp Phe Ile Glu Phe 35 40 45 atc atc aac gaa gag aac caa acc tgg ttc gcg gac aac tcc ttc cca 192 Ile Ile Asn Glu Glu Asn Gln Thr Trp Phe Ala Asp Asn Ser Phe Pro 50 55 60 cca gtt ctg gca tcc atc tac gat gat gag tcc ctt gtt gag cag tac 240 Pro Val Leu Ala Ser Ile Tyr Asp Asp Glu Ser Leu Val Glu Gln Tyr 65 70 75 80 cca tac ctg cca gca ctg aag gaa tcc ctg gaa aac gca gca cca cgc 288 Pro Tyr Leu Pro Ala Leu Lys Glu Ser Leu Glu Asn Ala Ala Pro Arg 85 90 95 cca gtg tct cct ttc tac cca gcc atc tcc aag gca atc cag gac aac 336 Pro Val Ser Pro Phe Tyr Pro Ala Ile Ser Lys Ala Ile Gln Asp Asn 100 105 110 gcc tac gca gcg ctt aac ggc aac gtc gac gtt gac cag gca acc acc 384 Ala Tyr Ala Ala Leu Asn Gly Asn Val Asp Val Asp Gln Ala Thr Thr 115 120 125 gat atg aag gca gcg atc gaa aac gct tcc agc tagttcggta atttagttca 437 Asp Met Lys Ala Ala Ile Glu Asn Ala Ser Ser 130 135 ttc 440 <210> 1154 <211> 139 <212> PRT <213> Corynebacterium glutamicum <400> 1154 Glu Ala Glu Ala Thr Ala Gly Lys Phe Glu Val Gln Pro Leu Val Gly 1 5 10 15 Lys Asp Gly Val Gly Val Ser Thr Leu Gly Gly Tyr Asn Asn Gly Ile 20 25 30 Asn Val Asn Ser Glu Asn Lys Ala Thr Ala Arg Asp Phe Ile Glu Phe 35 40 45 Ile Ile Asn Glu Glu Asn Gln Thr Trp Phe Ala Asp Asn Ser Phe Pro 50 55 60 Pro Val Leu Ala Ser Ile Tyr Asp Asp Glu Ser Leu Val Glu Gln Tyr 65 70 75 80 Pro Tyr Leu Pro Ala Leu Lys Glu Ser Leu Glu Asn Ala Ala Pro Arg 85 90 95 Pro Val Ser Pro Phe Tyr Pro Ala Ile Ser Lys Ala Ile Gln Asp Asn 100 105 110 Ala Tyr Ala Ala Leu Asn Gly Asn Val Asp Val Asp Gln Ala Thr Thr 115 120 125 Asp Met Lys Ala Ala Ile Glu Asn Ala Ser Ser 130 135 <210> 1155 <211> 1212 <212> DNA <213> Corynebacterium glutamicum <220> <221> CDS <222> (101)..(1189) <223> RXC00874 <400> 1155 agctgttccc taccattgct gaacgggagt ggattgtcac tttagcccct cacggattct 60 tctggtttga tctcaccgcc gatgaaaagg acgatatgga atg agc att ggc caa 115 Met Ser Ile Gly Gln 1 5 cac atc atc acc gag cgt ttc tac ggc gcc aag tcc cac acc atc gac 163 His Ile Ile Thr Glu Arg Phe Tyr Gly Ala Lys Ser His Thr Ile Asp 10 15 20 aac gta gat att gtg ttg tcc cgc gaa tgt ggc gag aac act ttg gct 211 Asn Val Asp Ile Val Leu Ser Arg Glu Cys Gly Glu Asn Thr Leu Ala 25 30 35 gta gtg cgc atc aac aat gcg ctg tat cag ttg ttg gtc aat gat gat 259 Val Val Arg Ile Asn Asn Ala Leu Tyr Gln Leu Leu Val Asn Asp Asp 40 45 50 ggc aaa gat gtt ctc aac gac cac gta gaa gag gtc ggt gcg agt ttc 307 Gly Lys Asp Val Leu Asn Asp His Val Glu Glu Val Gly Ala Ser Phe 55 60 65 gga gca tgg act ggc agc tct gct ttt ccc att ggc cct ttc act cca 355 Gly Ala Trp Thr Gly Ser Ser Ala Phe Pro Ile Gly Pro Phe Thr Pro 70 75 80 85 ctc ggc aca gaa caa tcc aat agc tct ttc atc acc gcc gac aat aaa 403 Leu Gly Thr Glu Gln Ser Asn Ser Ser Phe Ile Thr Ala Asp Asn Lys 90 95 100 gcg atc gtg aaa tac ttc cgc aaa tta gaa tcc ggg caa aac ccc gat 451 Ala Ile Val Lys Tyr Phe Arg Lys Leu Glu Ser Gly Gln Asn Pro Asp 105 110 115 gtg gag cta att tct aaa att tcc tcc tgc ccc aac atc gcg ccc atc 499 Val Glu Leu Ile Ser Lys Ile Ser Ser Cys Pro Asn Ile Ala Pro Ile 120 125 130 ctg ggt ttt tcc tcc gct gag atc tcc ggg gct aac tac acc ctg gtc 547 Leu Gly Phe Ser Ser Ala Glu Ile Ser Gly Ala Asn Tyr Thr Leu Val 135 140 145 atg gcg cag cag tac gtt cca ggt ttg gat ggc tgg tca cac gcg ctg 595 Met Ala Gln Gln Tyr Val Pro Gly Leu Asp Gly Trp Ser His Ala Leu 150 155 160 165 act act acc tct ggc agc ttt gca gag gat gca gaa aag atc ggc gaa 643 Thr Thr Thr Ser Gly Ser Phe Ala Glu Asp Ala Glu Lys Ile Gly Glu 170 175 180 gcc acc cgc aat gtt cac act gct ctt gca tcg gcc ttc cct act cgg 691 Ala Thr Arg Asn Val His Thr Ala Leu Ala Ser Ala Phe Pro Thr Arg 185 190 195 gta gtt ccc gta gaa gca ctc gcc gat gcg ctc act acc cgc ctt aat 739 Val Val Pro Val Glu Ala Leu Ala Asp Ala Leu Thr Thr Arg Leu Asn 200 205 210 gaa cta atc tcc caa gca ccc gaa atc gcc cgc ttc aaa gaa gca gcc 787 Glu Leu Ile Ser Gln Ala Pro Glu Ile Ala Arg Phe Lys Glu Ala Ala 215 220 225 atc gac ctc tac caa tcg ttg gaa ggc gaa gcc cac atc caa cgc atc 835 Ile Asp Leu Tyr Gln Ser Leu Glu Gly Glu Ala His Ile Gln Arg Ile 230 235 240 245 cac ggt gac ctc cac ttg ggg cag ctc atc aaa acc ccc gaa cgc tac 883 His Gly Asp Leu His Leu Gly Gln Leu Ile Lys Thr Pro Glu Arg Tyr 250 255 260 atc ctc atc gat ttc gaa ggc gaa cct gcc cgc cca ctt aat caa cga 931 Ile Leu Ile Asp Phe Glu Gly Glu Pro Ala Arg Pro Leu Asn Gln Arg 265 270 275 cgc ctc ccc gac tct ccc ctg aaa gat ctc gcc ggc atc atc aga tcc 979 Arg Leu Pro Asp Ser Pro Leu Lys Asp Leu Ala Gly Ile Ile Arg Ser 280 285 290 atc gac tac gca gcc tac ttc gac ggc gaa cac acc caa tgg gcc aac 1027 Ile Asp Tyr Ala Ala Tyr Phe Asp Gly Glu His Thr Gln Trp Ala Asn 295 300 305 gaa gcc acc gcg cta ttc ctc gac ggc tac gga tca att gaa gac caa 1075 Glu Ala Thr Ala Leu Phe Leu Asp Gly Tyr Gly Ser Ile Glu Asp Gln 310 315 320 325 gaa ctc ctc aat gcc tac att ctg gac aag gcg ttg tac gag gtt gcc 1123 Glu Leu Leu Asn Ala Tyr Ile Leu Asp Lys Ala Leu Tyr Glu Val Ala 330 335 340 tat gaa ata aac aac cgc ccc gac tgg gtg aaa atc cca ctc gag gcg 1171 Tyr Glu Ile Asn Asn Arg Pro Asp Trp Val Lys Ile Pro Leu Glu Ala 345 350 355 gtc gaa agg ctt cta gac tagttagtta ctctgcgtca aac 1212 Val Glu Arg Leu Leu Asp 360 <210> 1156 <211> 363 <212> PRT <213> Corynebacterium glutamicum <400> 1156 Met Ser Ile Gly Gln His Ile Ile Thr Glu Arg Phe Tyr Gly Ala Lys 1 5 10 15 Ser His Thr Ile Asp Asn Val Asp Ile Val Leu Ser Arg Glu Cys Gly 20 25 30 Glu Asn Thr Leu Ala Val Val Arg Ile Asn Asn Ala Leu Tyr Gln Leu 35 40 45 Leu Val Asn Asp Asp Gly Lys Asp Val Leu Asn Asp His Val Glu Glu 50 55 60 Val Gly Ala Ser Phe Gly Ala Trp Thr Gly Ser Ser Ala Phe Pro Ile 65 70 75 80 Gly Pro Phe Thr Pro Leu Gly Thr Glu Gln Ser Asn Ser Ser Phe Ile 85 90 95 Thr Ala Asp Asn Lys Ala Ile Val Lys Tyr Phe Arg Lys Leu Glu Ser 100 105 110 Gly Gln Asn Pro Asp Val Glu Leu Ile Ser Lys Ile Ser Ser Cys Pro 115 120 125 Asn Ile Ala Pro Ile Leu Gly Phe Ser Ser Ala Glu Ile Ser Gly Ala 130 135 140 Asn Tyr Thr Leu Val Met Ala Gln Gln Tyr Val Pro Gly Leu Asp Gly 145 150 155 160 Trp Ser His Ala Leu Thr Thr Thr Ser Gly Ser Phe Ala Glu Asp Ala 165 170 175 Glu Lys Ile Gly Glu Ala Thr Arg Asn Val His Thr Ala Leu Ala Ser 180 185 190 Ala Phe Pro Thr Arg Val Val Pro Val Glu Ala Leu Ala Asp Ala Leu 195 200 205 Thr Thr Arg Leu Asn Glu Leu Ile Ser Gln Ala Pro Glu Ile Ala Arg 210 215 220 Phe Lys Glu Ala Ala Ile Asp Leu Tyr Gln Ser Leu Glu Gly Glu Ala 225 230 235 240 His Ile Gln Arg Ile His Gly Asp Leu His Leu Gly Gln Leu Ile Lys 245 250 255 Thr Pro Glu Arg Tyr Ile Leu Ile Asp Phe Glu Gly Glu Pro Ala Arg 260 265 270 Pro Leu Asn Gln Arg Arg Leu Pro Asp Ser Pro Leu Lys Asp Leu Ala 275 280 285 Gly Ile Ile Arg Ser Ile Asp Tyr Ala Ala Tyr Phe Asp Gly Glu His 290 295 300 Thr Gln Trp Ala Asn Glu Ala Thr Ala Leu Phe Leu Asp Gly Tyr Gly 305 310 315 320 Ser Ile Glu Asp Gln Glu Leu Leu Asn Ala Tyr Ile Leu Asp Lys Ala 325 330 335 Leu Tyr Glu Val Ala Tyr Glu Ile Asn Asn Arg Pro Asp Trp Val Lys 340 345 350 Ile Pro Leu Glu Ala Val Glu Arg Leu Leu Asp 355 360 <210> 1157 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: primer <400> 1157 ggaaacagta tgaccatg 18 <210> 1158 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> Description of Artificial Sequence: primer <400> 1158 gtaaaacgac ggccagt 17

Claims (36)

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  23. 서열 번호 4에 기재된 아미노산 서열로 이루어진 폴리펩티드를 코딩하는 단리된 핵산 분자를 포함하는 발현 벡터로 형질전환된 숙주 세포를 배양하여 리신을 생산하는 것을 포함하는 리신의 제조 방법.
  24. 제23항에 있어서, 상기 배양으로부터 리신을 회수하는 단계를 추가로 포함하는 방법.
  25. 제23항에 있어서, 상기 세포가 코리네박테리움 속 또는 브레비박테리움 속에 포함되는 방법.
  26. 제23항에 있어서, 상기 세포가 코리네박테리움 글루타미쿰, 코리네박테리움 헤르쿨리스 (Corynebacterium herculis), 코리네박테리움 릴리움 (Corynebacterium lilium), 코리네박테리움 아세토아시도필룸 (Corynebacterium acetoacidophilum), 코리네박테리움 아세토글루타미쿰 (Corynebacterium acetoglutamicum), 코리네박테리움 아세토필룸 (Corynebacterium acetophilum), 코리네박테리움 암모니아게네스 (Corynebacterium ammoniagenes), 코리네박테리움 후지오켄세 (Corynebacterium fujiokense), 코리네박테리움 니트릴로필루스 (Corynebacterium nitrilophilus), 브레비박테리움 암모니아게네스 (Brevibacterium ammoniagenes), 브레비박테리움 부타니쿰 (Brevibacterium butanicum), 브레비박테리움 디바리카툼 (Brevibacterium divaricatum), 브레비박테리움 플라붐 (Brevibacterium flavum), 브레비박테리움 헤알리이 (Brevibacterium healii), 브레비박테리움 케토글루타미쿰 (Brevibacterium ketoglutamicum), 브레비박테리움 케토소레덕툼 (Brevibacterium ketosoreductum), 브레비박테리움 락토페르멘툼 (Brevibacterium lactofermentum), 브레비박테리움 리넨스 (Brevibacterium linens), 및 브레비박테리움 파라피놀리티쿰 (Brevibacterium paraffinolyticum)으로 구성된 군에서 선택되는 방법.
  27. 삭제
  28. 삭제
  29. 삭제
  30. 삭제
  31. 삭제
  32. 삭제
  33. 삭제
  34. 삭제
  35. 삭제
  36. 삭제
KR1020067022699A 1999-06-25 2000-06-23 대사 경로 단백질을 코딩하는 코리네박테리움 글루타미쿰유전자 KR100878334B1 (ko)

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