KR100204359B1 - Cell-free synthesis and isolation of novel gene and popyeptide - Google Patents

Cell-free synthesis and isolation of novel gene and popyeptide Download PDF

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Publication number
KR100204359B1
KR100204359B1 KR1019980708672A KR19980708672A KR100204359B1 KR 100204359 B1 KR100204359 B1 KR 100204359B1 KR 1019980708672 A KR1019980708672 A KR 1019980708672A KR 19980708672 A KR19980708672 A KR 19980708672A KR 100204359 B1 KR100204359 B1 KR 100204359B1
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South Korea
Prior art keywords
isolation
cell
free synthesis
popyeptide
novel gene
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KR1019980708672A
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English (en)
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Glen Kawasaki
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Optein Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6867—Replicase-based amplification, e.g. using Q-beta replicase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1019980708672A 1989-10-05 1998-10-28 Cell-free synthesis and isolation of novel gene and popyeptide KR100204359B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41735789A 1989-10-05 1989-10-05
KR1019920700769A KR0185192B1 (ko) 1989-10-05 1990-10-04 신규의 유전자 및 폴리펩티드의 무세포 합성 및 분리
PCT/US1990/005682 WO1991005058A1 (en) 1989-10-05 1990-10-04 Cell-free synthesis and isolation of novel genes and polypeptides

Publications (1)

Publication Number Publication Date
KR100204359B1 true KR100204359B1 (en) 1999-06-15

Family

ID=23653670

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1019920700769A KR0185192B1 (ko) 1989-10-05 1990-10-04 신규의 유전자 및 폴리펩티드의 무세포 합성 및 분리
KR1019980708673A KR100204360B1 (en) 1989-10-05 1998-10-28 A method for identifying a polynucleotide molecule having a selected nucleic acid sequence from a library of random or semi-random polynucleotide molecules
KR1019980708672A KR100204359B1 (en) 1989-10-05 1998-10-28 Cell-free synthesis and isolation of novel gene and popyeptide

Family Applications Before (2)

Application Number Title Priority Date Filing Date
KR1019920700769A KR0185192B1 (ko) 1989-10-05 1990-10-04 신규의 유전자 및 폴리펩티드의 무세포 합성 및 분리
KR1019980708673A KR100204360B1 (en) 1989-10-05 1998-10-28 A method for identifying a polynucleotide molecule having a selected nucleic acid sequence from a library of random or semi-random polynucleotide molecules

Country Status (11)

Country Link
US (2) US5658754A (ko)
EP (1) EP0494955B1 (ko)
JP (2) JP3127158B2 (ko)
KR (3) KR0185192B1 (ko)
AT (1) ATE168416T1 (ko)
AU (1) AU638762B2 (ko)
CA (1) CA2067194C (ko)
DE (1) DE69032483T2 (ko)
DK (1) DK0494955T3 (ko)
ES (1) ES2118066T3 (ko)
WO (1) WO1991005058A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100401296B1 (ko) * 2000-12-27 2003-10-11 드림바이오젠 주식회사 수식물질에 의해 수식된 단백질 변이체 및 이것의 제조방법

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