ATE44766T1 - Verfahren zur vergroesserung der expression eines bestimmten gens im bacillus subtilis und erhaltene staemme. - Google Patents
Verfahren zur vergroesserung der expression eines bestimmten gens im bacillus subtilis und erhaltene staemme.Info
- Publication number
- ATE44766T1 ATE44766T1 AT85400830T AT85400830T ATE44766T1 AT E44766 T1 ATE44766 T1 AT E44766T1 AT 85400830 T AT85400830 T AT 85400830T AT 85400830 T AT85400830 T AT 85400830T AT E44766 T1 ATE44766 T1 AT E44766T1
- Authority
- AT
- Austria
- Prior art keywords
- gene
- integration
- strains
- bacillus
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
- Y10S435/839—Bacillus subtilis
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8406701A FR2563533B1 (fr) | 1984-04-27 | 1984-04-27 | Procede d'amplification de l'expression d'un gene determine chez bacillus subtilis et souches obtenues |
EP85400830A EP0166628B1 (de) | 1984-04-27 | 1985-04-26 | Verfahren zur Vergrösserung der Expression eines bestimmten Gens im Bacillus subtilis und erhaltene Stämme |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE44766T1 true ATE44766T1 (de) | 1989-08-15 |
Family
ID=9303577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT85400830T ATE44766T1 (de) | 1984-04-27 | 1985-04-26 | Verfahren zur vergroesserung der expression eines bestimmten gens im bacillus subtilis und erhaltene staemme. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4959316A (de) |
EP (1) | EP0166628B1 (de) |
JP (1) | JPH0665306B2 (de) |
AT (1) | ATE44766T1 (de) |
DE (1) | DE3571646D1 (de) |
FR (1) | FR2563533B1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2637532B2 (ja) * | 1987-02-27 | 1997-08-06 | ギスト ブロカデス ナームローゼ フェンノートチャップ | 原核微生物の染色体dnaにおける安定した遺伝子増幅 |
FR2627508B1 (fr) * | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
JPH02211862A (ja) * | 1988-06-22 | 1990-08-23 | Toagosei Chem Ind Co Ltd | 抗昆虫蛋白産生枯草菌 |
JPH0669365B2 (ja) * | 1989-05-22 | 1994-09-07 | 株式会社ミドリ十字 | アルブミン遺伝子を含むプラスミド、形質転換体、形質転換体の製造方法、アルブミンの製造方法 |
CA2017176A1 (en) * | 1989-05-22 | 1990-11-22 | Yoshitomi Pharmaceutical Industries Ltd. | Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin |
FR2650292B1 (fr) * | 1989-07-27 | 1994-03-04 | Institut Recherche Agronomique | Procede de production de proteine a partir de souches de bacillus subtilis et procede de preparation desdites souches |
US5695976A (en) * | 1989-12-18 | 1997-12-09 | Novo Nordisk A/S | Stable integration of DNA in bacterial genomes |
DE4216246A1 (de) * | 1992-05-16 | 1993-11-18 | Solvay Enzymes Gmbh & Co Kg | Einfaches Verfahren zur stabilen chromosomalen Genamplifikation |
DK153992D0 (da) * | 1992-12-22 | 1992-12-22 | Novo Nordisk As | Metode |
US5733753A (en) * | 1992-12-22 | 1998-03-31 | Novo Nordisk A/S | Amplification of genomic DNA by site specific integration of a selectable marker construct |
US5861273A (en) * | 1993-12-21 | 1999-01-19 | Celtrix Phamraceuticals, Inc. | Chromosomal expression of heterologous genes in bacterial cells |
JP2002516116A (ja) * | 1998-05-27 | 2002-06-04 | ノボザイムス バイオテック,インコーポレイティド | 遺伝子のコピー数を変化させることによりポリペプチドを生産するための方法 |
EP1169466A4 (de) * | 1999-03-23 | 2005-02-23 | Univ Michigan State | Synthese von 1,2,3,4-tetrahydroxybenzole und 1,2,3-trihydroxybenzolen durch myo-inositol-1-phosphatsynthase und myo-inositol-2-dehydrogenase |
WO2006042548A1 (en) | 2004-10-22 | 2006-04-27 | Novozymes A/S | Stable genomic integration of multiple polynucleotide copies |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4336336A (en) * | 1979-01-12 | 1982-06-22 | President And Fellows Of Harvard College | Fused gene and method of making and using same |
GB2068971B (en) * | 1980-01-30 | 1983-06-08 | Searle & Co | Recombinant dna techniques |
EP0074808A3 (de) * | 1981-09-16 | 1984-07-04 | University Patents, Inc. | Rekombinantes Verfahren und Materialien |
DE113781T1 (de) * | 1982-07-09 | 1985-06-20 | Boyce Thompson Institute For Plant Research, Inc., Ithaca, N.Y. | Genetische transformation in prokaryotischem organismus. |
-
1984
- 1984-04-27 FR FR8406701A patent/FR2563533B1/fr not_active Expired
- 1984-06-05 JP JP59115355A patent/JPH0665306B2/ja not_active Expired - Lifetime
-
1985
- 1985-04-26 DE DE8585400830T patent/DE3571646D1/de not_active Expired
- 1985-04-26 EP EP85400830A patent/EP0166628B1/de not_active Expired
- 1985-04-26 AT AT85400830T patent/ATE44766T1/de not_active IP Right Cessation
-
1987
- 1987-12-18 US US07/135,515 patent/US4959316A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0166628B1 (de) | 1989-07-19 |
JPH0665306B2 (ja) | 1994-08-24 |
FR2563533A1 (fr) | 1985-10-31 |
JPS60234579A (ja) | 1985-11-21 |
FR2563533B1 (fr) | 1986-08-22 |
US4959316A (en) | 1990-09-25 |
EP0166628A1 (de) | 1986-01-02 |
DE3571646D1 (en) | 1989-08-24 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |