LT3389692T - Komplemento aktyvumo moduliatoriai - Google Patents

Komplemento aktyvumo moduliatoriai

Info

Publication number
LT3389692T
LT3389692T LTEP16823378.1T LT16823378T LT3389692T LT 3389692 T LT3389692 T LT 3389692T LT 16823378 T LT16823378 T LT 16823378T LT 3389692 T LT3389692 T LT 3389692T
Authority
LT
Lithuania
Prior art keywords
activity modulators
complete activity
complete
modulators
activity
Prior art date
Application number
LTEP16823378.1T
Other languages
English (en)
Inventor
Steven James DEMARCO
Michelle Denise HOARTY
Grace Victoria PARKER
Alonso RICARDO
Sylvia TOBE
Douglas A. Treco
Original Assignee
Ra Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ra Pharmaceuticals, Inc. filed Critical Ra Pharmaceuticals, Inc.
Publication of LT3389692T publication Critical patent/LT3389692T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEP16823378.1T 2015-12-16 2016-12-07 Komplemento aktyvumo moduliatoriai LT3389692T (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562268360P 2015-12-16 2015-12-16
US201662331320P 2016-05-03 2016-05-03
US201662347486P 2016-06-08 2016-06-08
PCT/US2016/065228 WO2017105939A1 (en) 2015-12-16 2016-12-07 Modulators of complement activity

Publications (1)

Publication Number Publication Date
LT3389692T true LT3389692T (lt) 2020-04-27

Family

ID=57758701

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP20157916.6T LT3685847T (lt) 2015-12-16 2016-12-07 Komplemento aktyvumo moduliatoriai
LTEP16823378.1T LT3389692T (lt) 2015-12-16 2016-12-07 Komplemento aktyvumo moduliatoriai

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP20157916.6T LT3685847T (lt) 2015-12-16 2016-12-07 Komplemento aktyvumo moduliatoriai

Country Status (25)

Country Link
US (3) US10835574B2 (lt)
EP (3) EP3389692B1 (lt)
JP (3) JP7126940B2 (lt)
KR (1) KR20180094913A (lt)
CN (2) CN108697759B (lt)
AU (1) AU2016370210A1 (lt)
CA (1) CA3007772A1 (lt)
CY (1) CY1123031T1 (lt)
DK (2) DK3389692T3 (lt)
ES (2) ES2941640T3 (lt)
FI (1) FI3685847T3 (lt)
HR (2) HRP20200508T1 (lt)
HU (1) HUE061759T2 (lt)
IL (1) IL259762B (lt)
LT (2) LT3685847T (lt)
MX (2) MX2018007352A (lt)
PL (2) PL3685847T3 (lt)
PT (2) PT3685847T (lt)
RS (2) RS64067B1 (lt)
RU (2) RU2769701C2 (lt)
SG (1) SG11201804721SA (lt)
SI (2) SI3685847T1 (lt)
SM (1) SMT202000213T1 (lt)
TW (2) TWI779805B (lt)
WO (1) WO2017105939A1 (lt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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ES2895029T3 (es) 2014-06-12 2022-02-17 Ra Pharmaceuticals Inc Modulación de actividad del complemento
HUE056613T2 (hu) 2015-01-28 2022-02-28 Ra Pharmaceuticals Inc Komplementaktivitás modulátorai
ES2941640T3 (es) 2015-12-16 2023-05-24 Ra Pharmaceuticals Inc Moduladores de la actividad del complemento
EP3551210A1 (en) * 2016-12-07 2019-10-16 RA Pharmaceuticals, Inc. Modulators of complement activity
CN111683672A (zh) 2017-12-04 2020-09-18 Ra制药公司 补体活性调节剂
AU2019370295A1 (en) * 2018-10-30 2021-06-03 Alexion Pharmaceuticals, Inc. Subcutaneous dosage and administration of anti-C5 antibodies for treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH)
CN113543796A (zh) 2019-03-08 2021-10-22 Ra制药公司 齐鲁考普作为深层组织穿透性c5抑制剂
BR112021017820A2 (pt) * 2019-04-24 2022-02-08 Ra Pharmaceuticals Inc Composições e métodos para modulação da atividade de complemento
EP3980047B1 (en) 2019-06-04 2024-02-14 RA Pharmaceuticals, Inc. Inflammatory disease treatment with complement inhibitors
WO2021050885A1 (en) 2019-09-12 2021-03-18 Ra Pharmaceuticals, Inc. Neurological disease treatment with complement inhibitors
BR112022021136A2 (pt) 2020-04-30 2022-11-29 Alnylam Pharmaceuticals Inc Composições de irna de fator b de complemento (cfb) e métodos de uso das mesmas
CA3234636A1 (en) 2021-10-29 2023-05-04 Alnylam Pharmaceuticals, Inc. Complement factor b (cfb) irna compositions and methods of use thereof

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Also Published As

Publication number Publication date
IL259762A (en) 2018-07-31
EP3389692A1 (en) 2018-10-24
TW201733609A (zh) 2017-10-01
JP7126940B2 (ja) 2022-08-29
TWI779805B (zh) 2022-10-01
BR112018012174A2 (pt) 2018-12-04
HRP20230182T1 (hr) 2023-04-14
ES2941640T3 (es) 2023-05-24
HRP20200508T1 (hr) 2020-09-04
RU2018121615A3 (lt) 2020-03-16
PT3685847T (pt) 2023-03-14
RU2018121615A (ru) 2020-01-20
US20180369322A1 (en) 2018-12-27
EP4218790A1 (en) 2023-08-02
SMT202000213T1 (it) 2020-05-08
RU2020131790A3 (lt) 2021-11-18
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