JP3681110B2 - Ｎ置換されている２−シアノピロリジン - Google Patents

Ｎ置換されている２−シアノピロリジン Download PDF

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Publication number
JP3681110B2
JP3681110B2 JP2000586689A JP2000586689A JP3681110B2 JP 3681110 B2 JP3681110 B2 JP 3681110B2 JP 2000586689 A JP2000586689 A JP 2000586689A JP 2000586689 A JP2000586689 A JP 2000586689A JP 3681110 B2 JP3681110 B2 JP 3681110B2
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compounds
formula
compound
dpp
pharmaceutically acceptable
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JP2002531547A (ja
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エドウィン・バーナード・ビルハウアー
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ノバルティス アクチエンゲゼルシャフト
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000586689A 1998-12-10 1999-12-09 Ｎ置換されている２−シアノピロリジン Expired - Lifetime JP3681110B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20906898A 1998-12-10 1998-12-10
US09/209,068 1998-12-10
PCT/EP1999/009708 WO2000034241A1 (en) 1998-12-10 1999-12-09 N-substituted 2-cyanopyrrolidines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2005008992A Division JP2005112864A (ja) 1998-12-10 2005-01-17 Ｎ置換されている２−シアノピロリジン

Publications (2)

Publication Number Publication Date
JP2002531547A JP2002531547A (ja) 2002-09-24
JP3681110B2 true JP3681110B2 (ja) 2005-08-10

Family

ID=22777194

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000586689A Expired - Lifetime JP3681110B2 (ja) 1998-12-10 1999-12-09 Ｎ置換されている２−シアノピロリジン
JP2005008992A Pending JP2005112864A (ja) 1998-12-10 2005-01-17 Ｎ置換されている２−シアノピロリジン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2005008992A Pending JP2005112864A (ja) 1998-12-10 2005-01-17 Ｎ置換されている２−シアノピロリジン

Country Status (34)

Country Link
US (1) US6166063A (enExample)
EP (1) EP1137635B1 (enExample)
JP (2) JP3681110B2 (enExample)
KR (2) KR100509311B1 (enExample)
CN (1) CN1160330C (enExample)
AR (1) AR023719A1 (enExample)
AT (1) ATE307112T1 (enExample)
BR (1) BRPI9915985B8 (enExample)
CA (1) CA2350609C (enExample)
CO (1) CO5150173A1 (enExample)
CY (3) CY1105355T1 (enExample)
CZ (1) CZ299151B6 (enExample)
DE (3) DE122008000007I1 (enExample)
DK (1) DK1137635T3 (enExample)
ES (1) ES2251847T3 (enExample)
FR (1) FR08C0005I2 (enExample)
HK (1) HK1040394B (enExample)
HU (1) HU226769B1 (enExample)
ID (1) ID28796A (enExample)
IL (2) IL143091A0 (enExample)
LU (2) LU91409I2 (enExample)
MY (1) MY123244A (enExample)
NL (2) NL300333I2 (enExample)
NO (3) NO318741B1 (enExample)
NZ (1) NZ511935A (enExample)
PE (1) PE20001317A1 (enExample)
PL (1) PL199443B1 (enExample)
RU (1) RU2251544C2 (enExample)
SK (1) SK286635B6 (enExample)
TR (1) TR200101478T2 (enExample)
TW (1) TW509674B (enExample)
UY (1) UY25843A1 (enExample)
WO (1) WO2000034241A1 (enExample)
ZA (1) ZA200104581B (enExample)

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* Cited by examiner, † Cited by third party
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