JP2018500944A5 - - Google Patents
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- JP2018500944A5 JP2018500944A5 JP2017553051A JP2017553051A JP2018500944A5 JP 2018500944 A5 JP2018500944 A5 JP 2018500944A5 JP 2017553051 A JP2017553051 A JP 2017553051A JP 2017553051 A JP2017553051 A JP 2017553051A JP 2018500944 A5 JP2018500944 A5 JP 2018500944A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021203925A JP2022050420A (ja) | 2014-12-29 | 2021-12-16 | キメラ抗原受容体発現細胞の製造法 |
| JP2024140764A JP2024167266A (ja) | 2014-12-29 | 2024-08-22 | キメラ抗原受容体発現細胞の製造法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462097375P | 2014-12-29 | 2014-12-29 | |
| US62/097,375 | 2014-12-29 | ||
| US201562133137P | 2015-03-13 | 2015-03-13 | |
| US62/133,137 | 2015-03-13 | ||
| PCT/US2015/067635 WO2016109410A2 (en) | 2014-12-29 | 2015-12-28 | Methods of making chimeric antigen receptor-expressing cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021203925A Division JP2022050420A (ja) | 2014-12-29 | 2021-12-16 | キメラ抗原受容体発現細胞の製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018500944A JP2018500944A (ja) | 2018-01-18 |
| JP2018500944A5 true JP2018500944A5 (enExample) | 2019-02-14 |
Family
ID=55315698
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017553051A Pending JP2018500944A (ja) | 2014-12-29 | 2015-12-28 | キメラ抗原受容体発現細胞の製造法 |
| JP2021203925A Withdrawn JP2022050420A (ja) | 2014-12-29 | 2021-12-16 | キメラ抗原受容体発現細胞の製造法 |
| JP2024140764A Pending JP2024167266A (ja) | 2014-12-29 | 2024-08-22 | キメラ抗原受容体発現細胞の製造法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021203925A Withdrawn JP2022050420A (ja) | 2014-12-29 | 2021-12-16 | キメラ抗原受容体発現細胞の製造法 |
| JP2024140764A Pending JP2024167266A (ja) | 2014-12-29 | 2024-08-22 | キメラ抗原受容体発現細胞の製造法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10273300B2 (enExample) |
| EP (2) | EP3240803B1 (enExample) |
| JP (3) | JP2018500944A (enExample) |
| KR (2) | KR102805767B1 (enExample) |
| CN (1) | CN107567461A (enExample) |
| AU (3) | AU2015374296B2 (enExample) |
| CA (2) | CA2972597A1 (enExample) |
| IL (2) | IL303247A (enExample) |
| RU (2) | RU2021118125A (enExample) |
| SG (1) | SG11201705293WA (enExample) |
| TW (1) | TW201631152A (enExample) |
| WO (1) | WO2016109410A2 (enExample) |
Families Citing this family (156)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150320799A1 (en) | 2012-12-20 | 2015-11-12 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3744736A1 (en) | 2013-02-20 | 2020-12-02 | Novartis AG | Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells |
| SG11201505896YA (en) | 2013-02-20 | 2015-09-29 | Novartis Ag | Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor |
| EP2970426B1 (en) | 2013-03-15 | 2019-08-28 | Michael C. Milone | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| CA3225453A1 (en) | 2013-12-19 | 2015-06-25 | Novartis Ag | Human mesothelin chimeric antigen receptors and uses thereof |
| EP3087101B1 (en) | 2013-12-20 | 2024-06-05 | Novartis AG | Regulatable chimeric antigen receptor |
| ES2963718T3 (es) | 2014-01-21 | 2024-04-01 | Novartis Ag | Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras |
| FI3888674T3 (fi) | 2014-04-07 | 2024-07-02 | Novartis Ag | Syövän hoito käyttäen kimeeristä anti-cd19-antigeenireseptoria |
| US11400115B2 (en) | 2014-04-23 | 2022-08-02 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| BR112017001242A2 (pt) | 2014-07-21 | 2017-12-05 | Novartis Ag | tratamento de câncer usando um receptor antigênico quimérico a cd33 |
| CN107109420A (zh) | 2014-07-21 | 2017-08-29 | 诺华股份有限公司 | 使用cll－1嵌合抗原受体的癌症治疗 |
| WO2016014553A1 (en) | 2014-07-21 | 2016-01-28 | Novartis Ag | Sortase synthesized chimeric antigen receptors |
| WO2016014565A2 (en) | 2014-07-21 | 2016-01-28 | Novartis Ag | Treatment of cancer using humanized anti-bcma chimeric antigen receptor |
| MY189028A (en) | 2014-08-19 | 2022-01-20 | Novartis Ag | Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment |
| CA2961636A1 (en) | 2014-09-17 | 2016-03-24 | Boris ENGELS | Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| CN106973568B (zh) | 2014-10-08 | 2021-07-23 | 诺华股份有限公司 | 预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途 |
| WO2016073955A2 (en) | 2014-11-06 | 2016-05-12 | President And Fellows Of Harvard College | Cells lacking b2m surface expression and methods for allogeneic administration of such cells |
| IL303247A (en) | 2014-12-29 | 2023-07-01 | Novartis Ag | Methods for preparing cells expressing a chimeric receptor antigen |
| US11459390B2 (en) | 2015-01-16 | 2022-10-04 | Novartis Ag | Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor |
| WO2016126608A1 (en) | 2015-02-02 | 2016-08-11 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| EP3543339A1 (en) | 2015-02-13 | 2019-09-25 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| IL254817B2 (en) | 2015-04-08 | 2023-12-01 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell |
| CN108473957B (zh) | 2015-04-17 | 2024-07-16 | 诺华股份有限公司 | 改善嵌合抗原受体表达细胞的功效和扩增的方法 |
| WO2016172583A1 (en) | 2015-04-23 | 2016-10-27 | Novartis Ag | Treatment of cancer using chimeric antigen receptor and protein kinase a blocker |
| HK1254190A1 (zh) | 2015-05-08 | 2019-07-12 | President And Fellows Of Harvard College | 通用供体干细胞和相关方法 |
| KR20180029201A (ko) | 2015-05-18 | 2018-03-20 | 티씨알2 테라퓨틱스 인크. | 융합 단백질을 이용하는 tcr 리프로그래밍을 위한 조성물 및 방법 |
| JP7146632B2 (ja) | 2015-07-21 | 2022-10-04 | ノバルティス アーゲー | 免疫細胞の有効性および増大を改善する方法 |
| WO2017027392A1 (en) | 2015-08-07 | 2017-02-16 | Novartis Ag | Treatment of cancer using chimeric cd3 receptor proteins |
| US11747346B2 (en) | 2015-09-03 | 2023-09-05 | Novartis Ag | Biomarkers predictive of cytokine release syndrome |
| JP2018536436A (ja) | 2015-12-04 | 2018-12-13 | ノバルティス アーゲー | 免疫腫瘍学のための組成物および方法 |
| MA44140A (fr) | 2015-12-22 | 2021-05-19 | Dana Farber Cancer Inst Inc | Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse |
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| WO2016126608A1 (en) | 2015-02-02 | 2016-08-11 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| ES2876974T3 (es) | 2015-04-07 | 2021-11-15 | Novartis Ag | Combinación de terapia con receptor de antígeno quimérico y derivados de amino pirimidina |
| IL254817B2 (en) | 2015-04-08 | 2023-12-01 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell |
| CN108473957B (zh) | 2015-04-17 | 2024-07-16 | 诺华股份有限公司 | 改善嵌合抗原受体表达细胞的功效和扩增的方法 |
| WO2016172583A1 (en) | 2015-04-23 | 2016-10-27 | Novartis Ag | Treatment of cancer using chimeric antigen receptor and protein kinase a blocker |
| CN105158466B (zh) | 2015-05-05 | 2017-12-22 | 中国科学院广州生物医药与健康研究院 | 一种检测抗cd19的嵌合抗原受体t细胞对白血病细胞抑制作用的方法 |
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| WO2017027392A1 (en) | 2015-08-07 | 2017-02-16 | Novartis Ag | Treatment of cancer using chimeric cd3 receptor proteins |
| US11747346B2 (en) | 2015-09-03 | 2023-09-05 | Novartis Ag | Biomarkers predictive of cytokine release syndrome |
| MX2018003353A (es) | 2015-09-17 | 2018-09-17 | Novartis Ag | Terapias con celulas cart con una eficacia mejorada. |
| CN109153975A (zh) | 2015-12-28 | 2019-01-04 | 诺华股份有限公司 | 制备嵌合抗原受体表达细胞的方法 |
| EP3523331A1 (en) | 2016-10-07 | 2019-08-14 | Novartis AG | Chimeric antigen receptors for the treatment of cancer |
| US10355389B2 (en) * | 2017-08-01 | 2019-07-16 | Delphi Technologies, Llc | High-current electrical terminal |
-
2015
- 2015-12-28 IL IL303247A patent/IL303247A/en unknown
- 2015-12-28 JP JP2017553051A patent/JP2018500944A/ja active Pending
- 2015-12-28 RU RU2021118125A patent/RU2021118125A/ru unknown
- 2015-12-28 AU AU2015374296A patent/AU2015374296B2/en active Active
- 2015-12-28 RU RU2017127051A patent/RU2751362C2/ru active
- 2015-12-28 TW TW104144073A patent/TW201631152A/zh unknown
- 2015-12-28 KR KR1020177020916A patent/KR102805767B1/ko active Active
- 2015-12-28 KR KR1020257014867A patent/KR20250075716A/ko active Pending
- 2015-12-28 SG SG11201705293WA patent/SG11201705293WA/en unknown
- 2015-12-28 WO PCT/US2015/067635 patent/WO2016109410A2/en not_active Ceased
- 2015-12-28 US US14/981,142 patent/US10273300B2/en active Active
- 2015-12-28 CA CA2972597A patent/CA2972597A1/en not_active Abandoned
- 2015-12-28 IL IL253149A patent/IL253149B2/en unknown
- 2015-12-28 EP EP15832850.0A patent/EP3240803B1/en active Active
- 2015-12-28 EP EP21209515.2A patent/EP4036109A3/en active Pending
- 2015-12-28 CN CN201580075647.3A patent/CN107567461A/zh active Pending
- 2015-12-28 CA CA3197849A patent/CA3197849A1/en active Pending
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2019
- 2019-03-04 US US16/291,651 patent/US20190292257A1/en not_active Abandoned
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2021
- 2021-11-30 AU AU2021277648A patent/AU2021277648A1/en not_active Abandoned
- 2021-12-16 JP JP2021203925A patent/JP2022050420A/ja not_active Withdrawn
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2023
- 2023-01-31 US US18/162,236 patent/US20230295296A1/en active Pending
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2024
- 2024-08-22 JP JP2024140764A patent/JP2024167266A/ja active Pending
- 2024-10-30 AU AU2024227744A patent/AU2024227744A1/en active Pending
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