CN110199015A - 修饰干细胞记忆t细胞、其制造方法与使用方法 - Google Patents

修饰干细胞记忆t细胞、其制造方法与使用方法 Download PDF

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CN110199015A
CN110199015A CN201780073874.1A CN201780073874A CN110199015A CN 110199015 A CN110199015 A CN 110199015A CN 201780073874 A CN201780073874 A CN 201780073874A CN 110199015 A CN110199015 A CN 110199015A
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cell
manufacturing
modified stem
stem cell
memory
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E.奥斯特塔
D.舍德洛克
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Wave Cedar Treatment Co
Poseida Therapeutics Inc
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Wave Cedar Treatment Co
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Abstract

本公开提供了一种生产修饰的干细胞样记忆T细胞(例如CAR‑T细胞)的方法，用于施用于受试者作为例如过继细胞疗法。
CN201780073874.1A 2016-09-30 2017-10-02 修饰干细胞记忆t细胞、其制造方法与使用方法 Pending CN110199015A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662402707P 2016-09-30 2016-09-30
US62/402707 2016-09-30
US201762502508P 2017-05-05 2017-05-05
US62/502508 2017-05-05
US201762553058P 2017-08-31 2017-08-31
US62/553058 2017-08-31
US201762556309P 2017-09-08 2017-09-08
US62/556309 2017-09-08
PCT/US2017/054799 WO2018064681A1 (en) 2016-09-30 2017-10-02 Modified stem cell memory t cells, methods of making and methods of using same

Publications (1)

Publication Number Publication Date
CN110199015A true CN110199015A (zh) 2019-09-03

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CN201780073874.1A Pending CN110199015A (zh) 2016-09-30 2017-10-02 修饰干细胞记忆t细胞、其制造方法与使用方法

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Country Link
EP (1) EP3519561A1 (zh)
JP (4) JP2019528760A (zh)
KR (3) KR102588469B1 (zh)
CN (1) CN110199015A (zh)
AU (3) AU2017337147A1 (zh)
CA (3) CA3036926C (zh)
IL (3) IL287286B (zh)
SG (2) SG11201901959YA (zh)
WO (1) WO2018064681A1 (zh)

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CA3036926C (en) * 2016-09-30 2022-05-31 Poseida Therapeutics, Inc. Modified stem cell memory t cells, methods of making and methods of using same
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EP3555273B1 (en) 2016-12-16 2024-05-22 B-Mogen Biotechnologies, Inc. ENHANCED hAT FAMILY TRANSPOSON-MEDIATED GENE TRANSFER AND ASSOCIATED COMPOSITIONS, SYSTEMS, AND METHODS
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CA3104288A1 (en) 2018-06-21 2019-12-26 B-Mogen Biotechnologies, Inc. Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods
US11058724B2 (en) * 2018-10-08 2021-07-13 Neutrolis, Inc. Methods of using DNASE1-like 3 in therapy
CN112996911A (zh) 2018-10-08 2021-06-18 纽特雷斯股份有限公司 用于制造和疗法的脱氧核糖核酸酶的工程改造
US10988746B2 (en) 2018-10-08 2021-04-27 Neutrolis, Inc. Manufacturing and engineering of DNASE enzymes for therapy
US11352613B2 (en) 2019-02-04 2022-06-07 Neutrolis, Inc. Engineered human extracellular DNASE enzymes
US11529427B2 (en) 2019-02-15 2022-12-20 Crispr Therapeutics Ag Gene editing for hemophilia A with improved factor VIII expression
KR20220004028A (ko) * 2019-04-26 2022-01-11 알로젠 테라퓨틱스 인코포레이티드 동종 car t 세포를 제조하는 방법
CN110358734B (zh) 2019-06-13 2020-08-25 首都医科大学宣武医院 以Tcm为主要效应成分的CAR-T制备方法及其应用
EP4110356A4 (en) * 2020-02-28 2024-03-27 Wisconsin Alumni Research Foundation NON-VIRAL GENERATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS OBTAINED BY GENE EDITING
CA3171092A1 (en) * 2020-03-13 2021-09-16 Stephen John GOULD Selectable marker proteins, expression vectors, for the production of virus-like particles for therapeutic and prophylactic applications
EP4298205A1 (en) * 2021-02-23 2024-01-03 Poseida Therapeutics, Inc. Genetically modified induced pluripotent stem cells and methods of use thereof
CN114990061B (zh) * 2022-06-30 2023-08-29 河南省人民医院 一种诱导扩增中央记忆性t细胞的培养方法

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