JP2024525609A5 - - Google Patents

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Publication number
JP2024525609A5
JP2024525609A5 JP2024500475A JP2024500475A JP2024525609A5 JP 2024525609 A5 JP2024525609 A5 JP 2024525609A5 JP 2024500475 A JP2024500475 A JP 2024500475A JP 2024500475 A JP2024500475 A JP 2024500475A JP 2024525609 A5 JP2024525609 A5 JP 2024525609A5
Authority
JP
Japan
Prior art keywords
sequence
polynucleotide according
polynucleotide
trop
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500475A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525609A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/073566 external-priority patent/WO2023283644A2/en
Publication of JP2024525609A publication Critical patent/JP2024525609A/ja
Publication of JP2024525609A5 publication Critical patent/JP2024525609A5/ja
Pending legal-status Critical Current

Links

JP2024500475A 2021-07-09 2022-07-08 Trop-2陽性癌を標的とするキメラ抗原受容体 Pending JP2024525609A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163220283P 2021-07-09 2021-07-09
US63/220,283 2021-07-09
PCT/US2022/073566 WO2023283644A2 (en) 2021-07-09 2022-07-08 Chimeric antigen receptor to target trop-2-positive cancers

Publications (2)

Publication Number Publication Date
JP2024525609A JP2024525609A (ja) 2024-07-12
JP2024525609A5 true JP2024525609A5 (enExample) 2025-07-07

Family

ID=84802126

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500475A Pending JP2024525609A (ja) 2021-07-09 2022-07-08 Trop-2陽性癌を標的とするキメラ抗原受容体

Country Status (10)

Country Link
US (1) US20240325444A1 (enExample)
EP (1) EP4366747A4 (enExample)
JP (1) JP2024525609A (enExample)
KR (1) KR20240034220A (enExample)
CN (1) CN117881407A (enExample)
AU (1) AU2022306051A1 (enExample)
CA (1) CA3224887A1 (enExample)
IL (1) IL309497A (enExample)
MX (1) MX2024000479A (enExample)
WO (1) WO2023283644A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4419128A4 (en) * 2021-10-20 2025-10-01 Univ Texas NK CELL ENGINEERING WITH CAR CONSTRUCTION WITH OPTIMAL SIGNALING
GB202318553D0 (en) * 2023-12-05 2024-01-17 Unikum Therapeutics Aps Engineered plasmacytoid dendritic cells
WO2025194098A1 (en) * 2024-03-14 2025-09-18 Dana-Farber Cancer Institute, Inc. Engineered immune cells expressing chimeric antigen receptors targeting trop2, and methods of using the same
CN119215188B (zh) * 2024-04-12 2025-09-05 英百瑞(杭州)生物医药有限公司 抗Trop2抗体和抗5T4抗体-自然杀伤细胞偶联物及其用途
CN118307680A (zh) * 2024-04-28 2024-07-09 华南农业大学 一种抗氯霉素单克隆抗体及其基于磁珠的自动化化学发光酶免疫检测方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2478047C (en) * 2002-03-01 2014-01-21 Immunomedics, Inc. Rs7 antibodies
EP3227340B1 (en) * 2014-12-04 2020-06-17 Mediterranea Theranostic S.R.L. Humanized anti-trop-2 monoclonal antibodies and uses thereof
AU2016274989A1 (en) * 2015-06-12 2017-11-02 Immunomedics, Inc. Disease therapy with chimeric antigen receptor (car) constructs and t cells (car-t) or nk cells (car-nk) expressing car constructs
WO2020009868A1 (en) * 2018-07-03 2020-01-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-slamf7 chimeric antigen receptors
CN112771166B (zh) * 2018-08-31 2025-03-04 诺伊尔免疫生物科技株式会社 表达car的t细胞和car表达载体
AU2019372673A1 (en) * 2018-11-01 2021-05-27 Gracell Biotechnologies (Shanghai) Co., Ltd. Compositions and methods for T cell engineering
CN119301157A (zh) * 2022-05-30 2025-01-10 地中海治疗有限责任公司 用于癌症治疗的抗活化的Trop-2的嵌合抗原受体构建体

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