JP2022548902A5 - - Google Patents

Info

Publication number
JP2022548902A5
JP2022548902A5 JP2022517339A JP2022517339A JP2022548902A5 JP 2022548902 A5 JP2022548902 A5 JP 2022548902A5 JP 2022517339 A JP2022517339 A JP 2022517339A JP 2022517339 A JP2022517339 A JP 2022517339A JP 2022548902 A5 JP2022548902 A5 JP 2022548902A5
Authority
JP
Japan
Prior art keywords
seq
cells
expression construct
scfv
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022517339A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022548902A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/050864 external-priority patent/WO2021055349A1/en
Publication of JP2022548902A publication Critical patent/JP2022548902A/ja
Publication of JP2022548902A5 publication Critical patent/JP2022548902A5/ja
Pending legal-status Critical Current

Links

JP2022517339A 2019-09-18 2020-09-15 Bcma陽性腫瘍を標的とするためのナチュラルキラー細胞の操作方法 Pending JP2022548902A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962902237P 2019-09-18 2019-09-18
US62/902,237 2019-09-18
PCT/US2020/050864 WO2021055349A1 (en) 2019-09-18 2020-09-15 A method of engineering natural killer-cells to target bcma-positive tumors

Publications (2)

Publication Number Publication Date
JP2022548902A JP2022548902A (ja) 2022-11-22
JP2022548902A5 true JP2022548902A5 (enExample) 2023-09-29

Family

ID=74883668

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022517339A Pending JP2022548902A (ja) 2019-09-18 2020-09-15 Bcma陽性腫瘍を標的とするためのナチュラルキラー細胞の操作方法

Country Status (7)

Country Link
US (1) US20220370500A1 (enExample)
EP (1) EP4031577A4 (enExample)
JP (1) JP2022548902A (enExample)
CN (1) CN114729046A (enExample)
AR (1) AR119990A1 (enExample)
TW (1) TW202124447A (enExample)
WO (1) WO2021055349A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
KR20240021179A (ko) * 2021-05-14 2024-02-16 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 키메라 폴리펩티드 및 사용 방법
IL311837A (en) 2021-10-20 2024-05-01 Takeda Pharmaceuticals Co Compositions targeting bcma and methods of use thereof
EP4419128A4 (en) * 2021-10-20 2025-10-01 Univ Texas NK CELL ENGINEERING WITH CAR CONSTRUCTION WITH OPTIMAL SIGNALING
EP4493581A1 (en) * 2022-03-18 2025-01-22 University of Rochester Combination therapy for treatment of cancer, methods and systems of delivery thereof
WO2024218688A1 (en) * 2023-04-18 2024-10-24 Board Of Regents, The University Of Texas System Bcma chimeric antigen receptors and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2766608C2 (ru) * 2012-04-11 2022-03-15 Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток
HRP20191873T1 (hr) * 2014-12-12 2020-01-24 Bluebird Bio, Inc. Kimerni antigenski receptori
US10294304B2 (en) * 2015-04-13 2019-05-21 Pfizer Inc. Chimeric antigen receptors targeting B-cell maturation antigen
US11655452B2 (en) * 2015-06-25 2023-05-23 Icell Gene Therapeutics Inc. Chimeric antigen receptors (CARs), compositions and methods of use thereof
EP3612210A4 (en) * 2017-04-19 2021-01-27 Board Of Regents, The University Of Texas System MANIPULATED ANTIGEN RECEPTORS EXPRESSING IMMUNE CELLS
CN117721084A (zh) * 2017-10-12 2024-03-19 美商生物细胞基因治疗有限公司 靶向多种抗原的复合嵌合抗原受体(cCAR)及其组成和使用方法
CN109468283A (zh) * 2018-11-30 2019-03-15 北京美康基免生物科技有限公司 一种基于cd19和bcma的双重嵌合抗原受体基因修饰的免疫细胞及其应用
CN109734814A (zh) * 2019-02-12 2019-05-10 南京卡提医学科技有限公司 具有免疫受体的工程化t细胞治疗癌症的用途

Similar Documents

Publication Publication Date Title
JP2022548902A5 (enExample)
JP2022184852A5 (enExample)
AU2016342560B2 (en) Receptor
JP2023509766A5 (enExample)
Colucci et al. What does it take to make a natural killer?
JP2022550899A5 (enExample)
EP3564266A1 (en) Novel chimeric antigen receptor and use thereof
JP6990244B2 (ja) ヒトcd123を標的とするキメラ受容体リガンド及びその応用
JP2022548943A5 (enExample)
JP2024519515A5 (enExample)
CN109280086B (zh) 一种肿瘤微环境特异性活化的缺氧诱导型嵌合抗原受体
JP2022542321A5 (enExample)
JP2024525492A5 (enExample)
JP2024513906A5 (enExample)
JP2024525609A5 (enExample)
KR20210018838A (ko) 유전자 조작된 세포 및 응용
AU2018321134B2 (en) Chimeric antigen receptor and CAR-T cells that bind CXCR5
JP2023548467A5 (enExample)
CN111479918A (zh) 细胞
JP2025501214A5 (enExample)
JP2024521566A5 (enExample)
JP2024527879A5 (enExample)
JP2024521185A5 (enExample)
WO2023193660A1 (zh) 增强型嵌合抗原受体及其应用
JP2023540551A (ja) 免疫療法組成物