JP2024521566A5 - - Google Patents

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Publication number
JP2024521566A5
JP2024521566A5 JP2023571468A JP2023571468A JP2024521566A5 JP 2024521566 A5 JP2024521566 A5 JP 2024521566A5 JP 2023571468 A JP2023571468 A JP 2023571468A JP 2023571468 A JP2023571468 A JP 2023571468A JP 2024521566 A5 JP2024521566 A5 JP 2024521566A5
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JP
Japan
Prior art keywords
cells
modified
receptor
seq
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023571468A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521566A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/093747 external-priority patent/WO2022242700A1/en
Publication of JP2024521566A publication Critical patent/JP2024521566A/ja
Publication of JP2024521566A5 publication Critical patent/JP2024521566A5/ja
Pending legal-status Critical Current

Links

JP2023571468A 2021-05-20 2022-05-19 遺伝子的に改変されたnk細胞およびその使用 Pending JP2024521566A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/094830 2021-05-20
CN2021094830 2021-05-20
PCT/CN2022/093747 WO2022242700A1 (en) 2021-05-20 2022-05-19 Genetically modified nk cells and uses thereof

Publications (2)

Publication Number Publication Date
JP2024521566A JP2024521566A (ja) 2024-06-03
JP2024521566A5 true JP2024521566A5 (enExample) 2025-05-27

Family

ID=84140259

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023571468A Pending JP2024521566A (ja) 2021-05-20 2022-05-19 遺伝子的に改変されたnk細胞およびその使用

Country Status (6)

Country Link
US (1) US20240285685A1 (enExample)
EP (1) EP4341383A4 (enExample)
JP (1) JP2024521566A (enExample)
KR (1) KR20240010717A (enExample)
CN (1) CN117355600A (enExample)
WO (1) WO2022242700A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202342736A (zh) * 2022-02-07 2023-11-01 中國大陸商杭州啟函生物科技有限公司 增強免疫療法的系統和方法
EP4353741A1 (en) * 2022-10-14 2024-04-17 ONK Therapeutics Limited Double knockout natural killer cells
CN115820645B (zh) * 2022-11-28 2023-09-22 上海恩凯细胞技术有限公司 制备沉默nkg2a基因的nk细胞的方法及其用途
CN115948341B (zh) * 2022-11-28 2025-05-16 上海恩凯细胞技术有限公司 敲低nkg2a基因的car-免疫细胞及其用途
TW202503051A (zh) * 2023-03-07 2025-01-16 美商英特利亞醫療公司 用於免疫療法之cish組合物及方法
CN116590237B (zh) * 2023-05-29 2023-10-31 上海贝斯昂科生物科技有限公司 一种遗传修饰的自然杀伤细胞及其制备和用途
US12681020B2 (en) 2024-03-20 2026-07-14 Immunitybio, Inc. Compositions and methods for NK-92 cells expressing native CD16
CN120989166B (zh) * 2025-10-21 2026-01-23 成都蓉生药业有限责任公司 一种慢病毒包膜质粒组合及其应用、慢病毒及其包装方法与转导造血干细胞的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL265953B2 (en) * 2016-10-19 2026-05-01 Cellectis Sa Gene insertion designed to target for enhanced immune cell therapy
WO2018126074A1 (en) * 2016-12-30 2018-07-05 Celularity, Inc. Genetically modified natural killer cells
CA3093919A1 (en) * 2018-03-15 2019-09-19 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
SG11202010763VA (en) * 2018-05-03 2020-11-27 Univ Texas Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
AU2019386140B2 (en) * 2018-11-28 2026-05-28 Board Of Regents, The University Of Texas System Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment
BR112021016046A2 (pt) * 2019-02-15 2021-11-09 Editas Medicine Inc Células assassinas naturais modificadas (nk) para imunoterapia
CN114174325A (zh) * 2019-06-04 2022-03-11 恩卡尔塔公司 用于免疫疗法的工程化自然杀伤细胞和工程化t细胞的组合
EP3789485A1 (en) * 2019-09-06 2021-03-10 ONK Therapeutics Limited Cellular therapies for cancer

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