JP2020513839A5 - - Google Patents
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- JP2020513839A5 JP2020513839A5 JP2019558994A JP2019558994A JP2020513839A5 JP 2020513839 A5 JP2020513839 A5 JP 2020513839A5 JP 2019558994 A JP2019558994 A JP 2019558994A JP 2019558994 A JP2019558994 A JP 2019558994A JP 2020513839 A5 JP2020513839 A5 JP 2020513839A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762445976P | 2017-01-13 | 2017-01-13 | |
| US62/445,976 | 2017-01-13 | ||
| PCT/US2018/013551 WO2018132695A1 (en) | 2017-01-13 | 2018-01-12 | Chimeric antigen receptors targeting tim-1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020513839A JP2020513839A (ja) | 2020-05-21 |
| JP2020513839A5 true JP2020513839A5 (enExample) | 2021-02-25 |
| JP7303749B2 JP7303749B2 (ja) | 2023-07-05 |
Family
ID=62840504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019558994A Active JP7303749B2 (ja) | 2017-01-13 | 2018-01-12 | Ｔｉｍ－１を標的とするキメラ抗原受容体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11541076B2 (enExample) |
| EP (1) | EP3568416A4 (enExample) |
| JP (1) | JP7303749B2 (enExample) |
| CN (1) | CN110494451B (enExample) |
| WO (1) | WO2018132695A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018064076A1 (en) | 2016-09-27 | 2018-04-05 | Cero Therapeutics, Inc. | Chimeric engulfment receptor molecules |
| JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
| DK3688032T3 (da) | 2017-09-26 | 2025-12-15 | Cero Therapeutics Holdings Inc | Kimære engulfment-receptormolekyler og anvendelsesfremgangsmåder |
| RU2020135107A (ru) | 2018-03-28 | 2022-04-29 | Серо Терапьютикс, Инк. | Клеточные иммунотерапевтические композиции и их применения |
| US12291557B2 (en) | 2018-03-28 | 2025-05-06 | Cero Therapeutics Holdings, Inc. | Chimeric TIM4 receptors and uses thereof |
| US12448426B2 (en) * | 2018-05-17 | 2025-10-21 | St. Jude Children's Research Hospital, Inc. | Chimeric antigen receptors with MYD88 and CD40 costimulatory domains |
| CN110615842B (zh) * | 2018-06-20 | 2023-05-09 | 上海隆耀生物科技有限公司 | 一种包含共刺激受体的嵌合抗原受体及应用 |
| AU2019314452B2 (en) * | 2018-08-02 | 2022-12-08 | Kite Pharma, Inc | Chimeric antigen receptor therapy T cell expansion kinetics and uses thereof |
| KR102879284B1 (ko) | 2018-08-29 | 2025-10-31 | 난징 레전드 바이오테크 씨오., 엘티디. | 항-메소텔린 키메라 항원 수용체(car) 작제물 및 이의 용도 |
| US20220144960A1 (en) | 2018-12-26 | 2022-05-12 | Nanjing Legend Biotech Co., Ltd. | Cd30-binding moieties, chimeric antigen receptors, and uses thereof |
| WO2020227446A1 (en) * | 2019-05-07 | 2020-11-12 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancement of polypeptides and chimeric antigen receptors via hinge domains |
| US20220265715A1 (en) * | 2019-07-24 | 2022-08-25 | Eureka Therapeutics, Inc. | Chimeric antigen receptor t cells and uses thereof |
| CN112079934B (zh) * | 2019-12-17 | 2021-01-29 | 合源生物科技(天津)有限公司 | 一种靶向cd19的嵌合抗原受体及其用途 |
| WO2021130535A2 (en) * | 2019-12-28 | 2021-07-01 | Shanghai Cell Therapy Group Company Co., Ltd. | Cell expressing immune modulatory molecules and system for expressing immune modulatory molecules |
| CN115698285A (zh) * | 2020-02-14 | 2023-02-03 | 小利兰·斯坦福大学董事会 | 具有cd2激活的嵌合抗原受体 |
| GB202004371D0 (en) * | 2020-03-26 | 2020-05-13 | Glaxosmithkline Ip Dev Ltd | CAR constructs |
| PH12022552323A1 (en) * | 2020-03-31 | 2023-12-04 | Chugai Pharmaceutical Co Ltd | Claudin-6 targeting multispecific antigen-binding molecules and uses thereof |
| US11707487B2 (en) * | 2020-04-13 | 2023-07-25 | Affyimmune Therapeutics, Inc. | EpCAM antibody and CAR-T cells |
| US12264190B2 (en) * | 2020-04-24 | 2025-04-01 | Astrazeneca Ab | Compositions and methods of treating cancer with chimeric antigen receptors |
| WO2021249384A1 (en) * | 2020-06-09 | 2021-12-16 | Hangzhou Leading Edge Pharmaceutical Ltd. | Compositions and methods for enhancing immune response |
| CN112063588A (zh) * | 2020-08-13 | 2020-12-11 | 南京北恒生物科技有限公司 | 工程化免疫细胞及其用途 |
| JP7868033B2 (ja) | 2020-08-14 | 2026-06-01 | セロ・セラピューティクス・ホールディングス・インコーポレイテッド | キメラｔｉｍ受容体およびその使用 |
| JP2023541253A (ja) * | 2020-09-10 | 2023-09-29 | ムスタング バイオ，インコーポレイテッド | 癌標的のｃａｒ－ｔ細胞を含む併用療法と、それを癌治療に使用する方法 |
| AU2021360477A1 (en) * | 2020-10-13 | 2023-06-15 | The Trustees Of The University Of Pennsylvania | In vivo targeting of t cells for mrna therapeutics |
| CN112830974B (zh) * | 2021-01-08 | 2022-07-26 | 深圳市珈钰生物科技有限公司 | 一种嵌合抗原受体、载体、人树突状细胞、细胞系、实体肿瘤治疗药物及制备方法和应用 |
| CN114149505B (zh) * | 2021-01-12 | 2022-11-04 | 北京门罗生物科技有限公司 | 治疗b细胞相关疾病的免疫细胞、制备方法及其应用 |
| CN114807044B (zh) * | 2021-04-30 | 2023-09-08 | 四川大学华西医院 | 一种具有高nkt细胞比例的car-cik细胞制备方法及应用 |
| US20250304915A1 (en) * | 2021-05-25 | 2025-10-02 | Institut Curie | Myeloid Cells Overexpressing BCL2 |
| CN115521917A (zh) * | 2021-06-25 | 2022-12-27 | 南京北恒生物科技有限公司 | 工程化免疫细胞及其用途 |
| CN113583122B (zh) * | 2021-07-29 | 2023-08-29 | 武汉华美生物工程有限公司 | 抗人sema4d抗体及其制备方法和应用 |
| CN115322257B (zh) * | 2021-08-16 | 2023-05-30 | 上海优替济生生物医药有限公司 | Bcma靶向抗体、嵌合抗原受体及其应用 |
| CA3233096A1 (en) * | 2021-10-20 | 2023-04-17 | Board Of Regents, The University Of Texas System | Engineering nk cells with a car construct with optimal signaling |
| CN116426483B (zh) * | 2021-12-30 | 2024-02-23 | 南京紫珑生物科技有限公司 | Cd258蛋白在免疫治疗中的应用 |
| CN115974976B (zh) * | 2022-11-23 | 2024-06-04 | 华中科技大学 | 拮抗多肽及用于制备抗急性肾损伤药物的应用 |
| US20250092362A1 (en) * | 2023-09-15 | 2025-03-20 | Terumo Bct, Inc. | System And Methods For Producing Chimeric Antigen Receptor Cells |
| CN119409822B (zh) * | 2024-11-01 | 2026-02-17 | 中国科学技术大学 | 抗体或其抗原结合片段及其应用 |
| WO2026105018A1 (en) * | 2024-11-12 | 2026-05-21 | Dana-Farber Cancer Institute, Inc. | Bak1/bax knockout in car-t cells, methods, uses, and compositions |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1401869T3 (da) * | 2001-06-01 | 2008-04-28 | Biogen Idec Inc | Molekyler og fremgangsmåder til inhibering af udskillkelse af kim 1 |
| AU2003228336B2 (en) | 2002-03-19 | 2009-07-30 | Curagen Corporation | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| CA2519528C (en) | 2003-03-19 | 2016-01-26 | Abgenix, Inc. | Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof |
| SG188175A1 (en) * | 2004-06-03 | 2013-03-28 | Novimmune Sa | Anti-cd3 antibodies and methods of use thereof |
| EP1957115B8 (en) | 2005-11-10 | 2014-03-05 | Celldex Therapeutics, Inc. | Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen |
| US9845362B2 (en) * | 2010-10-08 | 2017-12-19 | The University Of North Carolina At Charlotte | Compositions comprising chimeric antigen receptors, T cells comprising the same, and methods of using the same |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| US20150110792A1 (en) * | 2011-11-22 | 2015-04-23 | Biogen Idec Ma Inc. | ANTI-TIM-1 Antibodies And Uses Thereof |
| LT2884999T (lt) | 2012-08-20 | 2021-04-12 | Fred Hutchinson Cancer Research Center | Ląstelinės imunoterapijos būdas ir kompozicijos |
| CA2913052A1 (en) * | 2013-05-24 | 2014-11-27 | Board Of Regents, The University Of Texas System | Chimeric antigen receptor-targeting monoclonal antibodies |
| DK3105317T3 (en) * | 2014-02-14 | 2019-01-14 | Cellectis | Immunotherapy cells that are genetically engineered to target antigen on both immune cells and pathological cells |
| CN122399016A (zh) * | 2014-03-15 | 2026-07-17 | 诺华股份有限公司 | 使用嵌合抗原受体治疗癌症 |
| EP2939690A1 (en) * | 2014-04-29 | 2015-11-04 | Medizinische Hochschule Hannover | Vaccine |
| CA2965224A1 (en) * | 2014-10-24 | 2016-04-28 | Bcrt Holding Bv | T cell-based immunotherapeutics |
| US11459390B2 (en) * | 2015-01-16 | 2022-10-04 | Novartis Ag | Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor |
| WO2016126608A1 (en) * | 2015-02-02 | 2016-08-11 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| WO2016168595A1 (en) * | 2015-04-17 | 2016-10-20 | Barrett David Maxwell | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
-
2018
- 2018-01-12 US US16/477,609 patent/US11541076B2/en active Active
- 2018-01-12 WO PCT/US2018/013551 patent/WO2018132695A1/en not_active Ceased
- 2018-01-12 CN CN201880011066.7A patent/CN110494451B/zh active Active
- 2018-01-12 JP JP2019558994A patent/JP7303749B2/ja active Active
- 2018-01-12 EP EP18739365.7A patent/EP3568416A4/en active Pending
-
2022
- 2022-12-12 US US18/064,514 patent/US20230355673A1/en active Pending
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