JP2023518930A5 - - Google Patents
Info
- Publication number
- JP2023518930A5 JP2023518930A5 JP2022555955A JP2022555955A JP2023518930A5 JP 2023518930 A5 JP2023518930 A5 JP 2023518930A5 JP 2022555955 A JP2022555955 A JP 2022555955A JP 2022555955 A JP2022555955 A JP 2022555955A JP 2023518930 A5 JP2023518930 A5 JP 2023518930A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- receptor
- immune cell
- antigen
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062991493P | 2020-03-18 | 2020-03-18 | |
| US62/991,493 | 2020-03-18 | ||
| US202063004827P | 2020-04-03 | 2020-04-03 | |
| US63/004,827 | 2020-04-03 | ||
| US202063043237P | 2020-06-24 | 2020-06-24 | |
| US63/043,237 | 2020-06-24 | ||
| PCT/IB2021/052294 WO2021186397A1 (en) | 2020-03-18 | 2021-03-18 | Gpc3 car-t cell compositions and methods of making and using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023518930A JP2023518930A (ja) | 2023-05-09 |
| JP2023518930A5 true JP2023518930A5 (enExample) | 2024-03-29 |
| JP7875600B2 JP7875600B2 (ja) | 2026-06-18 |
Family
ID=77768047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022555955A Active JP7875600B2 (ja) | 2020-03-18 | 2021-03-18 | Ｇｐｃ３ ｃａｒ－ｔ細胞組成物、並びにそれを作製する方法及び使用する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12630597B2 (enExample) |
| EP (1) | EP4121516A4 (enExample) |
| JP (1) | JP7875600B2 (enExample) |
| KR (1) | KR102957804B1 (enExample) |
| CN (1) | CN115667500B (enExample) |
| WO (1) | WO2021186397A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| WO2021186395A1 (en) * | 2020-03-18 | 2021-09-23 | Eutilex Co., Ltd. | Gpc3 car- t cells secreting il-18 and methods of making and using the same |
| KR20240013094A (ko) | 2021-03-17 | 2024-01-30 | 마이얼로이드 테라퓨틱스, 인크. | 조작된 키메라 융합 단백질 조성물 및 그의 사용 방법 |
| WO2025183436A1 (ko) * | 2024-02-27 | 2025-09-04 | (주)이노베이션바이오 | Gpc3을 표적으로 하는 키메릭 항원 수용체 및 cd276을 표적으로 하는 키메릭 항원 수용체를 발현하는 면역 이펙터 세포 및 이의 용도 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005256113B2 (en) * | 2004-07-09 | 2011-02-10 | Chugai Seiyaku Kabushiki Kaisha | Anti-glypican 3 antibody |
| KR101296931B1 (ko) * | 2004-10-26 | 2013-08-14 | 추가이 세이야쿠 가부시키가이샤 | 변형된 당쇄를 갖는 항-글리피칸 3 항체 |
| EP3127921A1 (en) | 2007-09-26 | 2017-02-08 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substition in cdr |
| RU2505603C2 (ru) | 2007-09-26 | 2014-01-27 | Чугаи Сейяку Кабусики Кайся | Антитело против рецептора il-6 |
| KR20150126724A (ko) | 2007-09-28 | 2015-11-12 | 추가이 세이야쿠 가부시키가이샤 | 혈장 중 반응속도가 개선된 항-글리피칸-3 항체 |
| CL2009000647A1 (es) | 2008-04-04 | 2010-06-04 | Chugai Pharmaceutical Co Ltd | Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto. |
| CN104140974B (zh) * | 2013-05-08 | 2017-09-29 | 科济生物医药（上海）有限公司 | 编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞 |
| ES2851123T1 (es) * | 2014-09-26 | 2021-09-03 | Baylor College Medicine | Receptores quiméricos de antígeno específicos de glipicano-3 para inmunoterapia adoptiva |
| CN105713881B (zh) * | 2014-12-04 | 2019-12-06 | 科济生物医药（上海）有限公司 | 双靶向gpc3和asgpr1的转基因免疫效应细胞及其应用 |
| US11376326B2 (en) * | 2015-07-01 | 2022-07-05 | Chugai Seiyaku Kabushiki Kaisha | GPC3-targeting therapeutic agent which is administered to patient for whom the GPC3-targeting therapeutic agent is effective |
| CN110035768A (zh) * | 2016-07-26 | 2019-07-19 | 泰莎治疗私人有限公司 | 嵌合抗原受体 |
| TWI831365B (zh) | 2017-01-10 | 2024-02-01 | 國立大學法人山口大學 | 抗ｇｐｃ３抗體 |
| WO2020017479A1 (ja) * | 2018-07-17 | 2020-01-23 | ノイルイミューン・バイオテック株式会社 | 抗ｇｐｃ３一本鎖抗体を含むｃａｒ |
| WO2020033273A1 (en) * | 2018-08-04 | 2020-02-13 | AbCyte Therapeutics Inc. | Multi-function and multi-targeting car system and methods for use thereof |
| CN111116743B (zh) * | 2018-10-30 | 2022-01-28 | 迈威(上海)生物科技股份有限公司 | Hsp90抗体及其在抗真菌感染中的应用 |
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2021
- 2021-03-18 KR KR1020227035620A patent/KR102957804B1/ko active Active
- 2021-03-18 WO PCT/IB2021/052294 patent/WO2021186397A1/en not_active Ceased
- 2021-03-18 EP EP21771035.9A patent/EP4121516A4/en active Pending
- 2021-03-18 CN CN202180029132.5A patent/CN115667500B/zh active Active
- 2021-03-18 US US17/906,718 patent/US12630597B2/en active Active
- 2021-03-18 JP JP2022555955A patent/JP7875600B2/ja active Active