JP2021530233A5 - - Google Patents
Info
- Publication number
- JP2021530233A5 JP2021530233A5 JP2021502538A JP2021502538A JP2021530233A5 JP 2021530233 A5 JP2021530233 A5 JP 2021530233A5 JP 2021502538 A JP2021502538 A JP 2021502538A JP 2021502538 A JP2021502538 A JP 2021502538A JP 2021530233 A5 JP2021530233 A5 JP 2021530233A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- sequence
- seq
- acid residues
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862700178P | 2018-07-18 | 2018-07-18 | |
| US62/700,178 | 2018-07-18 | ||
| PCT/US2019/042245 WO2020018695A1 (en) | 2018-07-18 | 2019-07-17 | Chimeric receptors to steap1 and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021530233A JP2021530233A (ja) | 2021-11-11 |
| JP2021530233A5 true JP2021530233A5 (enExample) | 2022-07-26 |
| JP7459046B2 JP7459046B2 (ja) | 2024-04-01 |
Family
ID=67515138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021502538A Active JP7459046B2 (ja) | 2018-07-18 | 2019-07-17 | Ｓｔｅａｐ１に対するキメラ受容体及びその使用方法 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20210277148A1 (enExample) |
| EP (1) | EP3823993A1 (enExample) |
| JP (1) | JP7459046B2 (enExample) |
| KR (2) | KR20260017491A (enExample) |
| CN (2) | CN118955734A (enExample) |
| AR (1) | AR117950A1 (enExample) |
| AU (1) | AU2019307607B2 (enExample) |
| BR (1) | BR112021000914A2 (enExample) |
| CA (1) | CA3106653A1 (enExample) |
| CL (3) | CL2021000136A1 (enExample) |
| CO (1) | CO2021000660A2 (enExample) |
| CR (1) | CR20210091A (enExample) |
| EA (1) | EA202190304A1 (enExample) |
| IL (2) | IL280238B2 (enExample) |
| JO (1) | JOP20210011A1 (enExample) |
| MA (1) | MA53167A (enExample) |
| MX (2) | MX2021000617A (enExample) |
| PE (1) | PE20210315A1 (enExample) |
| PH (1) | PH12021550120A1 (enExample) |
| SA (1) | SA521421049B1 (enExample) |
| SG (1) | SG11202100464UA (enExample) |
| TW (2) | TWI860294B (enExample) |
| UY (1) | UY38309A (enExample) |
| WO (1) | WO2020018695A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202519260A (zh) | 2018-07-02 | 2025-05-16 | 美商安進公司 | 抗steap1抗原結合蛋白 |
| EP4433512A4 (en) * | 2021-11-19 | 2025-12-31 | Univ Pennsylvania | Genetically modified pan-leukocyte-specific CD45 antigen to facilitate T-lymphocyte therapy |
| EP4476267A4 (en) * | 2022-02-11 | 2026-01-07 | Fred Hutchinson Cancer Center | CHIMERIC ANTIGENIC RECEPTORS BINDING TO STEAP1 |
| GB202208119D0 (en) * | 2022-06-01 | 2022-07-13 | Univ Oslo Hf | Anti-steap1 car |
| CN116178532B (zh) * | 2023-01-30 | 2025-04-04 | 中国科学院武汉病毒研究所 | 一种古尔图病毒核蛋白的单克隆抗体及其应用 |
| AU2024274301A1 (en) * | 2023-05-16 | 2025-12-11 | Fred Hutchinson Cancer Center | Pro-inflammatory cytokine enhanced steap1 recombinant receptors |
| WO2025090749A1 (en) * | 2023-10-25 | 2025-05-01 | St. Jude Children's Research Hospital, Inc. | Chimeric antigen receptors targeting leucine rich repeat containing 15 (lrrc15) |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0281604B1 (en) | 1986-09-02 | 1993-03-31 | Enzon Labs Inc. | Single polypeptide chain binding molecules |
| US6319494B1 (en) | 1990-12-14 | 2001-11-20 | Cell Genesys, Inc. | Chimeric chains for receptor-associated signal transduction pathways |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US5869337A (en) | 1993-02-12 | 1999-02-09 | President And Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
| US5834266A (en) | 1993-02-12 | 1998-11-10 | President & Fellows Of Harvard College | Regulated apoptosis |
| US5830462A (en) | 1993-02-12 | 1998-11-03 | President & Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
| US20030036654A1 (en) | 1994-08-18 | 2003-02-20 | Holt Dennis A. | Synthetic multimerizing agents |
| US5827642A (en) | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| EP1086223B1 (en) * | 1998-06-01 | 2009-07-29 | Agensys, Inc. | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
| US6410319B1 (en) * | 1998-10-20 | 2002-06-25 | City Of Hope | CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| KR20030032922A (ko) | 2000-02-24 | 2003-04-26 | 싸이트 테라피스 인코포레이티드 | 세포의 동시 자극 및 농축 |
| US7446190B2 (en) * | 2002-05-28 | 2008-11-04 | Sloan-Kettering Institute For Cancer Research | Nucleic acids encoding chimeric T cell receptors |
| WO2007137300A2 (en) | 2006-05-23 | 2007-11-29 | Bellicum Pharmaceuticals, Inc. | Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods |
| BRPI0717638A2 (pt) * | 2006-10-27 | 2013-11-12 | Genentech Inc | Anticorpors e imunoconjugados e usos para os mesmos |
| US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| AU2012209103B2 (en) | 2011-01-26 | 2015-12-03 | Takeda Pharmaceutical Company Limited | Methods and compositions for the synthesis of multimerizing agents |
| US9987308B2 (en) | 2011-03-23 | 2018-06-05 | Fred Hutchinson Cancer Research Center | Method and compositions for cellular immunotherapy |
| AU2013329186B2 (en) * | 2012-10-10 | 2019-02-14 | Sangamo Therapeutics, Inc. | T cell modifying compounds and uses thereof |
| DK2956175T3 (da) | 2013-02-15 | 2017-11-27 | Univ California | Kimærisk antigenreceptor og fremgangsmåder til anvendelse deraf |
| CA2905352A1 (en) | 2013-03-14 | 2014-09-25 | Bellicum Pharmaceuticals, Inc. | Methods for controlling t cell proliferation |
| WO2014165818A2 (en) * | 2013-04-05 | 2014-10-09 | T Cell Therapeutics, Inc. | Compositions and methods for preventing and treating prostate cancer |
| CA3051222C (en) * | 2013-06-10 | 2023-01-24 | Dana-Farber Cancer Institute, Inc. | Methods and compositions for reducing immunosupression by tumor cells |
| EP3925618A1 (en) | 2013-07-29 | 2021-12-22 | 2seventy bio, Inc. | Multipartite signaling proteins and uses thereof |
| EP3087101B1 (en) | 2013-12-20 | 2024-06-05 | Novartis AG | Regulatable chimeric antigen receptor |
| CN113307880B (zh) * | 2014-01-13 | 2025-07-04 | 希望之城公司 | 在Fc间隔物区中具有突变的嵌合抗原受体(CAR)及其使用方法 |
| EP3096797A1 (en) * | 2014-01-24 | 2016-11-30 | F. Hoffmann-La Roche AG | Methods of using anti-steap1 antibodies and immunoconjugates |
| US10934346B2 (en) | 2014-02-14 | 2021-03-02 | Bellicum Pharmaceuticals, Inc. | Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12 |
| US20180080008A1 (en) * | 2014-08-12 | 2018-03-22 | Anthrogenesis Corporation | Car-t lymphocytes engineered to home to lymph node b cell zone, skin, or gastrointestinal tract |
| IL297773B2 (en) * | 2014-11-17 | 2024-07-01 | Adicet Bio Inc | Engineered gamma delta t-cells |
| CN108064246A (zh) * | 2015-06-15 | 2018-05-22 | 基因泰克公司 | 抗体和免疫结合物 |
| JP2018533930A (ja) * | 2015-10-02 | 2018-11-22 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 二重特異性ｔ細胞活性化抗原結合分子 |
| GB201518136D0 (en) * | 2015-10-14 | 2015-11-25 | Glaxosmithkline Ip Dev Ltd | Novel chimeric antigen receptors |
| EP3548055A4 (en) * | 2016-12-02 | 2020-08-19 | University of Southern California | SYNTHETIC IMMUNE RECEPTORS AND THEIR PROCESSES FOR USE |
| TW202519260A (zh) * | 2018-07-02 | 2025-05-16 | 美商安進公司 | 抗steap1抗原結合蛋白 |
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2019
- 2019-07-17 EA EA202190304A patent/EA202190304A1/ru unknown
- 2019-07-17 CN CN202411003355.6A patent/CN118955734A/zh active Pending
- 2019-07-17 KR KR1020267001194A patent/KR20260017491A/ko active Pending
- 2019-07-17 JP JP2021502538A patent/JP7459046B2/ja active Active
- 2019-07-17 IL IL280238A patent/IL280238B2/en unknown
- 2019-07-17 CA CA3106653A patent/CA3106653A1/en active Pending
- 2019-07-17 CN CN201980060357.XA patent/CN112771080B/zh active Active
- 2019-07-17 KR KR1020217004607A patent/KR102914114B1/ko active Active
- 2019-07-17 WO PCT/US2019/042245 patent/WO2020018695A1/en not_active Ceased
- 2019-07-17 SG SG11202100464UA patent/SG11202100464UA/en unknown
- 2019-07-17 IL IL324856A patent/IL324856A/en unknown
- 2019-07-17 MA MA053167A patent/MA53167A/fr unknown
- 2019-07-17 JO JOP/2021/0011A patent/JOP20210011A1/ar unknown
- 2019-07-17 PE PE2021000076A patent/PE20210315A1/es unknown
- 2019-07-17 BR BR112021000914-0A patent/BR112021000914A2/pt unknown
- 2019-07-17 EP EP19749064.2A patent/EP3823993A1/en active Pending
- 2019-07-17 AU AU2019307607A patent/AU2019307607B2/en active Active
- 2019-07-17 MX MX2021000617A patent/MX2021000617A/es unknown
- 2019-07-17 US US17/260,977 patent/US20210277148A1/en not_active Abandoned
- 2019-07-17 CR CR20210091A patent/CR20210091A/es unknown
- 2019-07-18 TW TW108125431A patent/TWI860294B/zh active
- 2019-07-18 TW TW113144512A patent/TWI902538B/zh active
- 2019-07-18 AR ARP190102027A patent/AR117950A1/es unknown
- 2019-07-19 UY UY0001038309A patent/UY38309A/es active IP Right Grant
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2021
- 2021-01-15 MX MX2025015568A patent/MX2025015568A/es unknown
- 2021-01-15 PH PH12021550120A patent/PH12021550120A1/en unknown
- 2021-01-17 SA SA521421049A patent/SA521421049B1/ar unknown
- 2021-01-18 CL CL2021000136A patent/CL2021000136A1/es unknown
- 2021-01-22 CO CONC2021/0000660A patent/CO2021000660A2/es unknown
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2023
- 2023-10-25 CL CL2023003182A patent/CL2023003182A1/es unknown
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2024
- 2024-12-30 CL CL2024004076A patent/CL2024004076A1/es unknown