JP2023518931A5 - - Google Patents
Info
- Publication number
- JP2023518931A5 JP2023518931A5 JP2022555957A JP2022555957A JP2023518931A5 JP 2023518931 A5 JP2023518931 A5 JP 2023518931A5 JP 2022555957 A JP2022555957 A JP 2022555957A JP 2022555957 A JP2022555957 A JP 2022555957A JP 2023518931 A5 JP2023518931 A5 JP 2023518931A5
- Authority
- JP
- Japan
- Prior art keywords
- immune cell
- cell according
- sequence
- receptor
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062991497P | 2020-03-18 | 2020-03-18 | |
| US62/991,497 | 2020-03-18 | ||
| US202063004912P | 2020-04-03 | 2020-04-03 | |
| US63/004,912 | 2020-04-03 | ||
| US202063043401P | 2020-06-24 | 2020-06-24 | |
| US63/043,401 | 2020-06-24 | ||
| PCT/IB2021/052292 WO2021186395A1 (en) | 2020-03-18 | 2021-03-18 | Gpc3 car- t cells secreting il-18 and methods of making and using the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023518931A JP2023518931A (ja) | 2023-05-09 |
| JP2023518931A5 true JP2023518931A5 (enExample) | 2024-03-27 |
| JP7778081B2 JP7778081B2 (ja) | 2025-12-01 |
Family
ID=77768034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022555957A Active JP7778081B2 (ja) | 2020-03-18 | 2021-03-18 | Ｉｌ－１８を分泌するｇｐｃ３ ｃａｒ－ｔ細胞、並びにそれを作製する方法及び使用する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230151113A1 (enExample) |
| EP (1) | EP4121517A4 (enExample) |
| JP (1) | JP7778081B2 (enExample) |
| KR (2) | KR20250154516A (enExample) |
| CN (1) | CN115461449A (enExample) |
| AU (1) | AU2021239060A1 (enExample) |
| CA (1) | CA3176125A1 (enExample) |
| WO (1) | WO2021186395A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL312606A (en) * | 2021-11-09 | 2024-07-01 | Janssen Biotech Inc | Microfluidic co-encapsulation device and system and methods for identifying t-cell receptor ligands |
| WO2025183436A1 (ko) * | 2024-02-27 | 2025-09-04 | (주)이노베이션바이오 | Gpc3을 표적으로 하는 키메릭 항원 수용체 및 cd276을 표적으로 하는 키메릭 항원 수용체를 발현하는 면역 이펙터 세포 및 이의 용도 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800479B2 (en) * | 2001-12-11 | 2004-10-05 | Samyang Genex Corporation | Recombinant adenoviruses expressing interleukin-18 protein and gene therapy using them |
| CL2009000647A1 (es) * | 2008-04-04 | 2010-06-04 | Chugai Pharmaceutical Co Ltd | Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto. |
| US20150329640A1 (en) * | 2012-12-20 | 2015-11-19 | Bluebird Bio, Inc. | Chimeric antigen receptors and immune cells targeting b cell malignancies |
| CN104140974B (zh) * | 2013-05-08 | 2017-09-29 | 科济生物医药（上海）有限公司 | 编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞 |
| ES2851123T1 (es) * | 2014-09-26 | 2021-09-03 | Baylor College Medicine | Receptores quiméricos de antígeno específicos de glipicano-3 para inmunoterapia adoptiva |
| US11173179B2 (en) * | 2015-06-25 | 2021-11-16 | Icell Gene Therapeutics Llc | Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof |
| US11376326B2 (en) * | 2015-07-01 | 2022-07-05 | Chugai Seiyaku Kabushiki Kaisha | GPC3-targeting therapeutic agent which is administered to patient for whom the GPC3-targeting therapeutic agent is effective |
| CN110035768A (zh) * | 2016-07-26 | 2019-07-19 | 泰莎治疗私人有限公司 | 嵌合抗原受体 |
| TWI831365B (zh) * | 2017-01-10 | 2024-02-01 | 國立大學法人山口大學 | 抗ｇｐｃ３抗體 |
| EP3615574B1 (en) * | 2017-04-26 | 2026-06-24 | Eureka Therapeutics, Inc. | Constructs specifically recognizing glypican 3 and uses thereof |
| WO2019210293A1 (en) * | 2018-04-27 | 2019-10-31 | Baylor College Of Medicine | Car t cells with one or more interleukins |
| US20220127570A1 (en) * | 2018-05-03 | 2022-04-28 | Cafa Therapeutics Limited | Immune effector cell and use thereof |
| CN110468105B (zh) * | 2018-05-09 | 2024-03-22 | 恺兴生命科技(上海)有限公司 | 表达il-18r结合蛋白的免疫效应细胞 |
| WO2020017479A1 (ja) * | 2018-07-17 | 2020-01-23 | ノイルイミューン・バイオテック株式会社 | 抗ｇｐｃ３一本鎖抗体を含むｃａｒ |
| KR102957804B1 (ko) * | 2020-03-18 | 2026-04-28 | 주식회사 유틸렉스 | Gpc3 car-t 세포 조성물 및 이의 제조 및 사용 방법 |
-
2021
- 2021-03-18 WO PCT/IB2021/052292 patent/WO2021186395A1/en not_active Ceased
- 2021-03-18 CA CA3176125A patent/CA3176125A1/en active Pending
- 2021-03-18 US US17/906,722 patent/US20230151113A1/en active Pending
- 2021-03-18 JP JP2022555957A patent/JP7778081B2/ja active Active
- 2021-03-18 CN CN202180029131.0A patent/CN115461449A/zh active Pending
- 2021-03-18 EP EP21771464.1A patent/EP4121517A4/en active Pending
- 2021-03-18 AU AU2021239060A patent/AU2021239060A1/en active Pending
- 2021-03-18 KR KR1020257033533A patent/KR20250154516A/ko active Pending
- 2021-03-18 KR KR1020227035621A patent/KR20220155589A/ko not_active Ceased