|
US2512572A
(en)
|
|
1950-06-20 |
|
Substituted pteridines and method |
|
DE267495C
(de)
|
1913-09-07 |
1913-11-20 |
Max Schreiber |
Sicherheitsschloss für schmucksachen
|
|
CH231852A
(de)
|
1940-08-09 |
1944-04-15 |
Ig Farbenindustrie Ag |
Verfahren zur Herstellung eines Kondensationsproduktes.
|
|
US2581889A
(en)
|
1948-07-07 |
1952-01-08 |
Burroughs Wellcome Co |
Method of preparing pyrimidopyrazines
|
|
US2665275A
(en)
|
1948-12-22 |
1954-01-05 |
Allen & Hanburys Ltd |
2, 4-diamino-7, 8-disubstituted pteridines
|
|
GB677342A
(en)
|
1949-08-19 |
1952-08-13 |
Ici Ltd |
New pyrimidine derivatives and their use in the manufacture of pteridin derivatives
|
|
US2667486A
(en)
|
1951-05-24 |
1954-01-26 |
Research Corp |
2,4-diamino pteridine and derivatives
|
|
GB763044A
(en)
|
1952-04-18 |
1956-12-05 |
Ici Ltd |
Pteridin derivatives
|
|
GB785353A
(en)
|
1953-01-30 |
1957-10-30 |
Merck & Co Inc |
Substituted pteridine derivatives
|
|
US2740784A
(en)
|
1954-05-03 |
1956-04-03 |
Merck & Co Inc |
Process for preparing pteridines
|
|
US2940972A
(en)
|
1957-06-27 |
1960-06-14 |
Thomae Gmbh Dr K |
Tri-and tetra-substituted pteridine derivatives
|
|
US2939882A
(en)
|
1958-07-21 |
1960-06-07 |
Shell Oil Co |
Stabilized alpha, beta-unsaturated aldehydes
|
|
US3081230A
(en)
|
1960-09-08 |
1963-03-12 |
Smith Kline French Lab |
Diuretic and antihypertensive triaminoarylpteridines
|
|
US3071587A
(en)
|
1961-07-25 |
1963-01-01 |
American Cyanamid Co |
Cyanoethyl-pteridines
|
|
US3159628A
(en)
|
1962-05-28 |
1964-12-01 |
Smith Kline French Lab |
Pteridine-5-oxide derivatives
|
|
US3122546A
(en)
|
1962-12-03 |
1964-02-25 |
American Home Prod |
4, 7-diamino-2-(substituted)-n-substituted-6-pteridinecarboxamides
|
|
US3162635A
(en)
|
1962-08-06 |
1964-12-22 |
Searle & Co |
1, 2, 3, 4-tetrahydro-2, 4-pteridinediones and intermediates
|
|
NL131481C
(cg-RX-API-DMAC10.html)
|
1965-04-15 |
|
|
|
|
DE1921308A1
(de)
|
1969-04-25 |
1971-01-07 |
Boehringer Sohn Ingelheim |
Herzwirksame Zubereitungen
|
|
GB1301319A
(cg-RX-API-DMAC10.html)
|
1970-07-13 |
1972-12-29 |
|
|
|
US3859287A
(en)
|
1971-05-05 |
1975-01-07 |
Walter Wesley Parish |
Thiopteridines and process for producing same
|
|
US3843791A
(en)
|
1973-01-11 |
1974-10-22 |
Pfizer |
Method of killing insects with quinazolinones and quinazoline-thiones
|
|
DE3023369A1
(de)
|
1980-06-23 |
1982-01-14 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Aryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
|
|
AU572792B2
(en)
|
1982-09-20 |
1988-05-19 |
Wellcome Foundation Limited, The |
2-amino, 4-oxo-pteridine derivatives
|
|
DE3323932A1
(de)
|
1983-07-02 |
1985-01-10 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel
|
|
DE3445298A1
(de)
|
1984-12-12 |
1986-06-12 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
|
|
US5149705A
(en)
|
1987-03-13 |
1992-09-22 |
Allergan, Inc. |
Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid like activity
|
|
IT1204612B
(it)
|
1987-05-14 |
1989-03-10 |
Bioresearch Spa |
Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica
|
|
IL88507A
(en)
|
1987-12-03 |
1993-02-21 |
Smithkline Beckman Intercredit |
2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
|
|
US5252608A
(en)
|
1988-02-25 |
1993-10-12 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US4943593A
(en)
|
1988-02-25 |
1990-07-24 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5059714A
(en)
|
1988-02-25 |
1991-10-22 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5182297A
(en)
|
1988-02-25 |
1993-01-26 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5021456A
(en)
|
1988-02-25 |
1991-06-04 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US4965288A
(en)
|
1988-02-25 |
1990-10-23 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
DE3833393A1
(de)
|
1988-10-01 |
1990-04-05 |
Thomae Gmbh Dr K |
Verwendung von pteridinen zur verhinderung der primaeren und sekundaeren resistenz bei der chemotherapie und diese verbindungen enthaltende arzneimittel
|
|
US5120764A
(en)
|
1988-11-01 |
1992-06-09 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
GB8910722D0
(en)
*
|
1989-05-10 |
1989-06-28 |
Smithkline Beckman Intercredit |
Compounds
|
|
CA2015981A1
(en)
*
|
1989-05-10 |
1990-11-10 |
Thomas H. Brown |
Compounds
|
|
GB8912336D0
(en)
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US4997854A
(en)
|
1989-08-25 |
1991-03-05 |
Trustees Of Boston University |
Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
|
|
DE4009941A1
(de)
|
1990-03-28 |
1991-10-02 |
Thomae Gmbh Dr K |
Verwendung von pteridinen zur sensibilisierung resistenter plasmodien bei der malaria-chemotherapie und diese verbindungen enthaltende arzneimittel
|
|
PT100905A
(pt)
|
1991-09-30 |
1994-02-28 |
Eisai Co Ltd |
Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
|
|
GB9125001D0
(en)
|
1991-11-25 |
1992-01-22 |
Ici Plc |
Heterocyclic compounds
|
|
WO1993015077A1
(fr)
|
1992-01-27 |
1993-08-05 |
Chugai Seiyaku Kabushiki Kaisha |
Derive de methotrexate
|
|
AU4535893A
(en)
|
1992-06-15 |
1994-01-04 |
Regents Of The University Of California, The |
Screening assay for the identification of immunosuppressive drugs
|
|
HU214331B
(hu)
|
1992-06-17 |
1998-03-02 |
Gyógyszerkutató Intézet Kft. |
Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
|
|
WO1994006431A1
(en)
|
1992-09-22 |
1994-03-31 |
Cell Therapeutics, Inc. |
Novel epoxide-containing compounds
|
|
GB9221220D0
(en)
|
1992-10-09 |
1992-11-25 |
Sandoz Ag |
Organic componds
|
|
US5473070A
(en)
|
1992-11-16 |
1995-12-05 |
Cell Therapeutics, Inc. |
Substituted long chain alcohol xanthine compounds
|
|
WO1994014065A1
(en)
|
1992-12-14 |
1994-06-23 |
Dana-Farber Cancer Institute, Inc. |
Methods for identifying and using immunosuppressant compounds
|
|
IL108630A0
(en)
|
1993-02-18 |
1994-05-30 |
Fmc Corp |
Insecticidal substituted 2,4-diaminoquinazolines
|
|
PH31122A
(en)
|
1993-03-31 |
1998-02-23 |
Eisai Co Ltd |
Nitrogen-containing fused-heterocycle compounds.
|
|
US5641783A
(en)
|
1993-11-12 |
1997-06-24 |
Cell Therapeutics, Inc. |
Substituted amino alcohol compounds
|
|
US5670506A
(en)
|
1993-04-05 |
1997-09-23 |
Cell Therapeutics, Inc. |
Halogen, isothiocyanate or azide substituted xanthines
|
|
US5281603A
(en)
|
1993-04-23 |
1994-01-25 |
American Cyanamid Company |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
US5521190A
(en)
|
1993-05-27 |
1996-05-28 |
Fmc Corporation |
Insecticidal pterdines and 8-deazapteridines
|
|
US6043228A
(en)
|
1993-06-08 |
2000-03-28 |
Cancer Research Campaign Technology Limited |
O6 -substituted guanine derivatives, a process for their preparation and their use in treating tumor cells
|
|
AU1090795A
(en)
|
1993-11-12 |
1995-05-29 |
Cell Therapeutics, Inc. |
Method for preventing tissue injury from hypoxia
|
|
JPH07138238A
(ja)
|
1993-11-16 |
1995-05-30 |
Kanebo Ltd |
新規キナゾリン誘導体およびそれを有効成分とする抗腫瘍剤
|
|
US5525711A
(en)
|
1994-05-18 |
1996-06-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Pteridine nucleotide analogs as fluorescent DNA probes
|
|
DE4418096A1
(de)
|
1994-05-24 |
1995-11-30 |
Cassella Ag |
Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase
|
|
DE4418097A1
(de)
|
1994-05-24 |
1995-11-30 |
Cassella Ag |
Verwendung von Tetrahydropteridin-Derivaten als Hemmstoffe der NO-Synthase
|
|
US5929046A
(en)
|
1994-06-08 |
1999-07-27 |
Cancer Research Campaign Technology Limited |
Pyrimidine and purine derivatives and their use in treating tumour cells
|
|
US5607936A
(en)
|
1994-09-30 |
1997-03-04 |
Merck & Co., Inc. |
Substituted aryl piperazines as neurokinin antagonists
|
|
GB9424233D0
(en)
|
1994-11-30 |
1995-01-18 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US6323201B1
(en)
|
1994-12-29 |
2001-11-27 |
The Regents Of The University Of California |
Compounds for inhibition of ceramide-mediated signal transduction
|
|
DE69534438T2
(de)
|
1994-12-29 |
2006-06-29 |
The Regents Of The University Of California, Oakland |
Verbindungen für Ceramid-vermittelter Signalübertragung
|
|
US5843943A
(en)
|
1994-12-29 |
1998-12-01 |
The Regents Of The University Of California |
Compounds for inhibition of ceramide-mediated signal transduction
|
|
WO1997023616A1
(de)
|
1995-12-22 |
1997-07-03 |
BUNDESREPUBLIK DEUTSCHLAND, vertreten durch den BUNDESMINISTER FÜR GESUNDHEIT |
Polypeptide mit il-16-aktivität, verfahren zu ihrer herstellung und verwendung
|
|
US5780462A
(en)
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
|
GB9603095D0
(en)
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US5663335A
(en)
|
1996-03-01 |
1997-09-02 |
Pharmagenesis, Inc. |
Immunosuppressive compounds and methods
|
|
AU2666997A
(en)
|
1996-04-15 |
1997-11-07 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
In vitro prognostic test for progressors and non-progressors after hiv infection
|
|
ATE295847T1
(de)
|
1996-07-31 |
2005-06-15 |
Cmic Co Ltd |
Aktivsauerstoffaufnehmer enthaltende pterinderivate
|
|
ATE252385T1
(de)
|
1996-08-30 |
2003-11-15 |
Daiichi Suntory Pharma Co Ltd |
Vorbeugende oder heilende mittel für krankheiten, die durch mangel an stickoxid-synthase (nos) ausgelöst sind
|
|
EP0837063A1
(en)
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
|
US6203723B1
(en)
|
1998-03-12 |
2001-03-20 |
Ying Yen Hsu |
Microencapsulated liquid crystal having multidomains induced by the polymer network and method
|
|
AU2960599A
(en)
|
1998-03-30 |
1999-10-18 |
Akira Karasawa |
Quinazoline derivatives
|
|
DE69812070T2
(de)
|
1998-04-24 |
2003-12-11 |
K.U. Leuven Research & Development, Leuven |
Immununterdrückende Effekte von 8 substituierten Xanthinderivaten
|
|
JP2000038350A
(ja)
|
1998-05-18 |
2000-02-08 |
Yoshitomi Pharmaceut Ind Ltd |
糖尿病治療薬
|
|
JP4315300B2
(ja)
|
1998-08-10 |
2009-08-19 |
大日本住友製薬株式会社 |
新規なキナゾリン誘導体
|
|
JP4342007B2
(ja)
*
|
1998-08-10 |
2009-10-14 |
大日本住友製薬株式会社 |
キナゾリン誘導体
|
|
US5992713A
(en)
|
1998-10-23 |
1999-11-30 |
Manabat; Gregorio S. |
Clothes hanger with slidable side attachments
|
|
US7276506B2
(en)
|
1998-12-28 |
2007-10-02 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
ATE277929T1
(de)
|
1998-12-28 |
2004-10-15 |
4 Aza Bioscience Nv |
Immunsuppressive wirkungen von pteridinderivaten
|
|
JP2002536320A
(ja)
|
1999-02-02 |
2002-10-29 |
カー・イュー・ルーベン・リサーチ・アンド・ディベロップメント |
プテリジン誘導体の免疫抑制作用
|
|
US6946465B2
(en)
|
1999-02-02 |
2005-09-20 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
|
CA2393896A1
(en)
|
1999-09-15 |
2001-03-22 |
Warner-Lambert Company |
Pteridinones as kinase inhibitors
|
|
DE19944767A1
(de)
|
1999-09-17 |
2001-03-29 |
Vasopharm Biotech Gmbh & Co Kg |
N-substituierte 4-Aminopteridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US6440991B1
(en)
|
2000-10-02 |
2002-08-27 |
Wyeth |
Ethers of 7-desmethlrapamycin
|
|
SE0003828D0
(sv)
|
2000-10-20 |
2000-10-20 |
Astrazeneca Ab |
Novel compounds
|
|
DE10059864A1
(de)
|
2000-11-30 |
2002-06-13 |
Gruenenthal Gmbh |
Substituierte Amino-furan-2-yl-essigsäure- und Amino-thien-2-yl-essigsäure-Derivate
|
|
EP1382603B1
(en)
|
2001-04-26 |
2008-07-23 |
Eisai R&D Management Co., Ltd. |
Nitrogenous fused-ring compound having pyrazolyl group as substituent and medicinal composition thereof
|
|
CA2451800A1
(en)
|
2001-06-28 |
2003-01-09 |
Essential Therapeutics, Inc. |
Fused pyrimidines as d-alanyl-d-alanine ligase inhibitors
|
|
FR2828206B1
(fr)
|
2001-08-03 |
2004-09-24 |
Centre Nat Rech Scient |
Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
|
|
US7344702B2
(en)
|
2004-02-13 |
2008-03-18 |
Bristol-Myers Squibb Pharma Company |
Contrast agents for myocardial perfusion imaging
|
|
WO2003031406A2
(en)
|
2001-10-12 |
2003-04-17 |
Irm Llc |
Kinase inhibitor scaffolds and methods for their preparation
|
|
DE10202468A1
(de)
|
2002-01-23 |
2004-09-30 |
Faustus Forschungs Cie. Translational Cancer Research Gmbh |
Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
|
|
EP1511738A4
(en)
|
2002-05-17 |
2007-05-09 |
Scios Inc |
TREATMENT OF FIBROPROLIFERATIVE DISEASES USING TGF BETA INHIBITORS
|
|
JP2006502236A
(ja)
|
2002-09-18 |
2006-01-19 |
ファイザー・プロダクツ・インク |
形質転換成長因子（ｔｇｆ）阻害剤としてのトリアゾール誘導体
|
|
US7208493B2
(en)
|
2002-10-03 |
2007-04-24 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
US20050282814A1
(en)
|
2002-10-03 |
2005-12-22 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
AU2003286711A1
(en)
|
2002-10-25 |
2004-05-13 |
Vertex Pharmaceuticals Incorporated |
Indazolinone compositions useful as kinase inhibitors
|
|
WO2004065392A1
(en)
|
2003-01-24 |
2004-08-05 |
Smithkline Beecham Corporation |
Condensed pyridines and pyrimidines and their use as alk-5 receptor ligands
|
|
CL2004000234A1
(es)
|
2003-02-12 |
2005-04-15 |
Biogen Idec Inc |
Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid
|
|
PL1628685T3
(pl)
|
2003-04-25 |
2011-05-31 |
Gilead Sciences Inc |
Przeciwwirusowe analogi fosfonianowe
|
|
US7378409B2
(en)
|
2003-08-21 |
2008-05-27 |
Bristol-Myers Squibb Company |
Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
|
|
DK1658081T3
(da)
|
2003-08-29 |
2008-02-25 |
4 Aza Ip Nv |
Immunsuppressive virkninger af pteridinderivater
|
|
DK1663244T3
(da)
|
2003-09-12 |
2007-12-03 |
4 Aza Ip Nv |
Pteridin-derivater til behandling af TNF-alpha-beslægtede sygdomme
|
|
GB2405793A
(en)
|
2003-09-12 |
2005-03-16 |
4 Aza Bioscience Nv |
Pteridine derivatives for treating TNF-alpha related disorders
|
|
PE20050952A1
(es)
|
2003-09-24 |
2005-12-19 |
Novartis Ag |
Derivados de isoquinolina como inhibidores de b-raf
|
|
PL1673092T3
(pl)
|
2003-10-17 |
2008-01-31 |
4 Aza Ip Nv |
Pochodne pterydyny podstawione heterocyklem i ich zastosowanie w leczeniu
|
|
CA2545340A1
(en)
|
2003-11-10 |
2005-05-26 |
Synta Pharmaceuticals, Corp. |
Fused heterocyclic compounds
|
|
WO2005063752A1
(en)
|
2003-12-30 |
2005-07-14 |
Vasopharm Biotech Gmbh |
4-amino-7,8-dihydropteridines, pharmaceutical compositions containing them and their use for the treatment of diseases which are caused by an increased nitric oxide level
|
|
ATE476428T1
(de)
|
2004-01-22 |
2010-08-15 |
Lilly Co Eli |
Selektive modulatoren des östrogenrezeptors zur behandlung von vasomotorischen symptomen
|
|
JPWO2005080377A1
(ja)
|
2004-02-20 |
2007-10-25 |
キリンホールディングス株式会社 |
ＴＧＦβ阻害活性を有する化合物およびそれを含んでなる医薬組成物
|
|
CA2564175A1
(en)
|
2004-04-28 |
2005-11-10 |
Arrow Therapeutics Limited |
Chemical compounds
|
|
PT2612862T
(pt)
|
2004-05-13 |
2016-12-15 |
Icos Corp |
Quinazolinonas como inibidores de fosfatidilinositol 3-quinase delta humana
|
|
CN1583747A
(zh)
|
2004-05-26 |
2005-02-23 |
中国药科大学 |
蝶呤类一氧化氮合酶抑制剂
|
|
US8318701B2
(en)
|
2004-07-27 |
2012-11-27 |
Gilead Sciences, Inc. |
Phosphonate analogs of HIV inhibitor compounds
|
|
GB0417905D0
(en)
|
2004-08-11 |
2004-09-15 |
Novartis Ag |
Organic compounds
|
|
US7730363B2
(en)
|
2004-09-30 |
2010-06-01 |
Toshiba Solutions Corporation |
Reliability evaluation system, reliability evaluating method, and reliability evaluation program for information system
|
|
US20070054916A1
(en)
|
2004-10-01 |
2007-03-08 |
Amgen Inc. |
Aryl nitrogen-containing bicyclic compounds and methods of use
|
|
WO2006050843A1
(en)
*
|
2004-11-09 |
2006-05-18 |
F. Hoffmann-La Roche Ag |
Aminoquinazolines compounds
|
|
DE102004057645A1
(de)
|
2004-11-29 |
2006-06-01 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
|
|
DE102004057595A1
(de)
|
2004-11-29 |
2006-06-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
|
|
BRPI0516373A
(pt)
*
|
2004-12-30 |
2008-09-02 |
4 Aza Ip Nv |
derivados de pirido(3,2-d)pirimidinas e uso dos mesmos
|
|
GB0428475D0
(en)
|
2004-12-30 |
2005-02-02 |
4 Aza Bioscience Nv |
Pyrido(3,2-D)pyrimidine derivatives and pharmaceutical compositions useful as medicines for the treatment of autoimmune disorders
|
|
US20090264415A2
(en)
|
2004-12-30 |
2009-10-22 |
Steven De Jonghe |
Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for medical treatment
|
|
GB0503506D0
(en)
|
2005-02-21 |
2005-03-30 |
4 Aza Bioscience Nv |
Substituted pyrido(2,3-d) pyrimidine derivatives and pharmaceutical compositions useful as medicines for the treatment of autoimmune disorders
|
|
US20090142345A1
(en)
|
2005-03-15 |
2009-06-04 |
Takeda Pharmaceutical Company Limited |
Prophylactic/therapeutic agent for cancer
|
|
AR056347A1
(es)
|
2005-05-12 |
2007-10-03 |
Tibotec Pharm Ltd |
Uso de compuestos de pteridina para fabricar medicamentos y composiciones farmaceuticas
|
|
US7418747B1
(en)
|
2005-06-13 |
2008-09-02 |
Myers Jason D |
Furniture
|
|
CA2612788A1
(en)
|
2005-06-24 |
2006-12-28 |
Steven Cesar Alfons De Jonghe |
Pyrido(3,2-d)pyrimidines and pharmaceutical compositions useful for treating hepatitis c
|
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之胺基二氮雜呯
|
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之８-經取代苯并氮雜呯
|
|
ES2374455T3
(es)
|
2006-02-17 |
2012-02-16 |
Pfizer Limited |
Derivados de 3-deazapurinza como moduladores de tlr7.
|
|
WO2007135027A1
(de)
|
2006-05-24 |
2007-11-29 |
Boehringer Ingelheim International Gmbh |
Substituierte pteridine, die mit einem viergliedrigen heterocyclus substituiert sind
|
|
CA2652840C
(en)
|
2006-05-24 |
2014-09-09 |
Boehringer Ingelheim International Gmbh |
2-piperazino-6-chloro-pteridines as pde4-inhibitors for the treatment of inflammatory diseases
|
|
EP1870400A1
(en)
|
2006-06-08 |
2007-12-26 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Salts and crystalline salt forms of an 2-indolinone derivative
|
|
US20090318456A1
(en)
|
2006-07-06 |
2009-12-24 |
Gilead Sciences, Inc. |
Substituted pteridines for the treatment and prevention of viral infections
|
|
US8673929B2
(en)
|
2006-07-20 |
2014-03-18 |
Gilead Sciences, Inc. |
4,6-di- and 2,4,6-trisubstituted quinazoline derivatives and pharmaceutical compositions useful for treating viral infections
|
|
DE102006033718B4
(de)
|
2006-07-20 |
2017-10-19 |
Siemens Aktiengesellschaft |
Elektrische Maschine mit schräg verlaufenden Magnetpolgrenzen
|
|
WO2008009078A2
(en)
|
2006-07-20 |
2008-01-24 |
Gilead Sciences, Inc. |
4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
|
|
WO2008009079A2
(en)
|
2006-07-20 |
2008-01-24 |
Gilead Sciences, Inc. |
Substituted pteridines useful for the treatment and prevention of viral infections
|
|
US8338435B2
(en)
*
|
2006-07-20 |
2012-12-25 |
Gilead Sciences, Inc. |
Substituted pyrido(3,2-D) pyrimidines and pharmaceutical compositions for treating viral infections
|
|
WO2008024977A2
(en)
|
2006-08-24 |
2008-02-28 |
Serenex, Inc. |
Isoquinoline, quinazoline and phthalazine derivatives
|
|
US8027888B2
(en)
|
2006-08-31 |
2011-09-27 |
Experian Interactive Innovation Center, Llc |
Online credit card prescreen systems and methods
|
|
US8637531B2
(en)
|
2006-12-26 |
2014-01-28 |
Gilead Sciences, Inc. |
Pyrido(3,2-d)pyridmidines useful for treating viral infections
|
|
US8143394B2
(en)
|
2006-12-26 |
2012-03-27 |
Gilead Sciences, Inc. |
Pyrido(3,2-d)pyrimidines useful for treating viral infections
|
|
TW200840584A
(en)
|
2006-12-26 |
2008-10-16 |
Gilead Sciences Inc |
Pyrido(3,2-d)pyrimidines useful for treating viral infections
|
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
US8633186B2
(en)
|
2007-06-08 |
2014-01-21 |
Senomyx Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
ES2541434T3
(es)
|
2007-06-29 |
2015-07-20 |
Gilead Sciences, Inc. |
Derivados de purina y su uso como moduladores del receptor de tipo Toll 7
|
|
DK2185198T3
(en)
|
2007-08-02 |
2015-04-20 |
Gilead Biologics Inc |
LOX AND LOXL2 INHIBITORS AND APPLICATIONS THEREOF
|
|
BRPI0820307A2
(pt)
|
2007-11-16 |
2019-09-24 |
Boehringer Ingelheim Int |
inibidores de replicação do vírus da imunodeficiência humana
|
|
WO2009072915A1
(en)
|
2007-12-05 |
2009-06-11 |
Bial - Portela & Ca., S.A. |
New salts and crystal forms
|
|
WO2010002998A1
(en)
|
2008-07-03 |
2010-01-07 |
Gilead Sciences, Inc. |
2,4,6-TRISUBSTITUTED PYRIDO (3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS
|
|
WO2010002877A2
(en)
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
DK2315756T5
(en)
|
2008-07-08 |
2015-08-03 |
Incyte Corp |
1,2,5-oxadiazoles as inhibitors of indoleamine-2,3-dioxygenase
|
|
CA2732437C
(en)
|
2008-08-01 |
2017-11-21 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
|
US8652843B2
(en)
|
2008-08-12 |
2014-02-18 |
Oncomed Pharmaceuticals, Inc. |
DDR1-binding agents and methods of use thereof
|
|
US20110281908A1
(en)
|
2008-10-06 |
2011-11-17 |
Emory University |
Aminoquinoline Derived Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use
|
|
GB0819593D0
(en)
|
2008-10-24 |
2008-12-03 |
Ucb Pharma Sa |
Therapeutic agents
|
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
|
TW201639852A
(zh)
|
2008-12-09 |
2016-11-16 |
吉李德科學股份有限公司 |
用於製備可用作類鐸受體調節劑之化合物的中間體化合物
|
|
WO2010092340A1
(en)
|
2009-02-13 |
2010-08-19 |
Ucb Pharma S.A. |
Fused pyridine and pyrazine derivatives as kinase inhibitors
|
|
PE20120509A1
(es)
|
2009-05-13 |
2012-05-09 |
Gilead Sciences Inc |
Derivados 9,9 difluoro-9h-fluoreno que tiene actividad antiviral
|
|
US8338441B2
(en)
|
2009-05-15 |
2012-12-25 |
Gilead Sciences, Inc. |
Inhibitors of human immunodeficiency virus replication
|
|
TWI598347B
(zh)
|
2009-07-13 |
2017-09-11 |
基利科學股份有限公司 |
調節細胞凋亡信號之激酶的抑制劑
|
|
RU2580320C2
(ru)
|
2009-08-18 |
2016-04-10 |
Вентиркс Фармасьютикалз, Инк. |
Замещенные бензоазепины в качестве модуляторов toll-подобного рецептора
|
|
RU2593261C2
(ru)
|
2009-08-18 |
2016-08-10 |
Вентиркс Фармасьютикалс, Инк. |
Замещенные бензоазепины в качестве модуляторов toll-подобных рецепторов
|
|
NO2491035T3
(cg-RX-API-DMAC10.html)
|
2009-10-22 |
2018-01-27 |
|
|
|
WO2011057148A1
(en)
|
2009-11-05 |
2011-05-12 |
Irm Llc |
Compounds and compositions as tlr-7 activity modulators
|
|
EP2521724B1
(en)
|
2009-12-11 |
2016-11-23 |
Nono Inc. |
Agents and methods for treating ischemic and other diseases
|
|
SG183174A1
(en)
|
2010-02-04 |
2012-09-27 |
Gilead Biologics Inc |
Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor
|
|
WO2011097607A1
(en)
|
2010-02-08 |
2011-08-11 |
Southern Research Institute |
Anti-viral treatment and assay to screen for anti-viral agent
|
|
FR2959510B1
(fr)
*
|
2010-04-28 |
2013-04-26 |
Centre Nat Rech Scient |
Derives de pyrido[3,2-d]pyrimidine, leurs procedes de preparation et leurs utilisations therapeutiques
|
|
US20130165489A1
(en)
|
2010-05-03 |
2013-06-27 |
The Trustees Of The University Of Pennsylvania |
Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof
|
|
ES2592152T3
(es)
|
2010-05-31 |
2016-11-28 |
Ono Pharmaceutical Co., Ltd. |
Derivado de purinona como inhibidor de Btk quinasa
|
|
MX2012015097A
(es)
|
2010-07-02 |
2013-05-28 |
Gilead Sciences Inc |
Derivados de acido naft-2-ilacetico para tratar sida.
|
|
US9296758B2
(en)
|
2010-07-02 |
2016-03-29 |
Gilead Sciences, Inc. |
2-quinolinyl-acetic acid derivatives as HIV antiviral compounds
|
|
KR101930179B1
(ko)
|
2010-08-27 |
2018-12-17 |
길리아드 바이오로직스, 인크. |
매트릭스 메탈로프로테이나제 ９에 대한 항체
|
|
CA2812790A1
(en)
|
2010-10-01 |
2012-04-05 |
Robert Hershberg |
Therapeutic use of a tlr agonist and combination therapy
|
|
CA2812787A1
(en)
|
2010-10-01 |
2012-04-05 |
Robert Hershberg |
Methods for the treatment of allergic diseases
|
|
US8940740B2
(en)
|
2010-10-28 |
2015-01-27 |
Southern Research Institute |
Small molecule inhibitors of bacterial motility and a high throughput screening assay for their identification
|
|
CN103298474B
(zh)
*
|
2010-11-10 |
2016-06-29 |
无限药品股份有限公司 |
杂环化合物及其用途
|
|
UY33775A
(es)
|
2010-12-10 |
2012-07-31 |
Gilead Sciences Inc |
Inhibidores macrocíclicos de virus flaviviridae, composiciones farmacéuticas que los comprenden y sus usos
|
|
HRP20170401T1
(hr)
|
2011-01-12 |
2017-05-19 |
Ventirx Pharmaceuticals, Inc. |
SUPSTITUIRANI BENZOAZEPINI KAO MODULATORI TOLL-u SLIČNIH RECEPTORA
|
|
CA2824786A1
(en)
|
2011-01-12 |
2012-07-19 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
BR112013020425A2
(pt)
|
2011-02-12 |
2017-06-13 |
Globeimmune Inc |
composições e métodos para o tratamento ou prevenção de infecção por vírus da hepatite b
|
|
US8664230B2
(en)
|
2011-03-17 |
2014-03-04 |
The Asan Foundation |
Pyridopyrimidine derivatives and use thereof
|
|
JP6046694B2
(ja)
|
2011-04-08 |
2016-12-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染治療用のピリミジン誘導体
|
|
EP3181555B1
(en)
|
2011-04-21 |
2018-11-28 |
Gilead Sciences, Inc. |
Benzothiazole compounds and their pharmaceutical use
|
|
RS57023B1
(sr)
*
|
2011-05-18 |
2018-05-31 |
Janssen Sciences Ireland Uc |
Derivati hinazolina za tretman viralnih infekcija i drugih bolesti
|
|
ES2553449T3
(es)
|
2011-07-06 |
2015-12-09 |
Gilead Sciences, Inc. |
Compuestos para el tratamiento de VIH
|
|
CN102863512B
(zh)
|
2011-07-07 |
2016-04-20 |
上海泓博智源医药技术有限公司 |
抗病毒化合物
|
|
AU2012284088B2
(en)
*
|
2011-07-19 |
2015-10-08 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2013027802A1
(ja)
|
2011-08-23 |
2013-02-28 |
中外製薬株式会社 |
抗腫瘍活性を有する新規な抗ｄｄｒ１抗体
|
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
|
US8466159B2
(en)
|
2011-10-21 |
2013-06-18 |
Abbvie Inc. |
Methods for treating HCV
|
|
WO2013060881A1
(en)
*
|
2011-10-27 |
2013-05-02 |
Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg |
Pyridopyrimidines and their therapeutic use
|
|
JP5704252B2
(ja)
|
2011-11-29 |
2015-04-22 |
小野薬品工業株式会社 |
プリノン誘導体塩酸塩
|
|
WO2013090840A1
(en)
|
2011-12-15 |
2013-06-20 |
Gilead Sciences, Inc. |
2 -amino- pyrido [3, 2 -d] pyrimidine derivatives as hcv inhibitors
|
|
JP6144698B2
(ja)
|
2011-12-20 |
2017-06-07 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｈｉｖ複製の阻害剤としての縮合三環式化合物
|
|
JP5977837B2
(ja)
|
2011-12-21 |
2016-08-24 |
ノヴィラ・セラピューティクス・インコーポレイテッド |
Ｂ型肝炎抗ウイルス剤
|
|
UY34573A
(es)
|
2012-01-27 |
2013-06-28 |
Gilead Sciences Inc |
Inhibidor de la quinasa que regula la señal de la apoptosis
|
|
MX357296B
(es)
|
2012-02-08 |
2018-07-03 |
Janssen Sciences Ireland Uc |
Derivados piperidinopirimidinicos para el tratamiento de infecciones viricas.
|
|
US20130267517A1
(en)
|
2012-03-31 |
2013-10-10 |
Hoffmann-La Roche Inc. |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
MD20140063A2
(ro)
|
2012-04-20 |
2014-12-31 |
Gilead Sciences, Inc. |
Derivaţi de acid benzotiazol-6-il acetic şi utilizarea acestora pentru tratarea unei infecţii HIV
|
|
EP2852439A1
(en)
|
2012-05-23 |
2015-04-01 |
Stemergie Biotechnology SA |
Inhibitors of the activity of complex (iii) of the mitochondrial electron transport chain and use thereof
|
|
PL2861604T3
(pl)
|
2012-06-08 |
2017-08-31 |
Gilead Sciences, Inc. |
Makrocykliczne inhibitory wirusów flaviviridae
|
|
AR091279A1
(es)
|
2012-06-08 |
2015-01-21 |
Gilead Sciences Inc |
Inhibidores macrociclicos de virus flaviviridae
|
|
EA201492205A1
(ru)
|
2012-06-08 |
2015-10-30 |
Джилид Сайэнс, Инк. |
Макроциклические ингибиторы вирусов flaviviridae
|
|
KR102216479B1
(ko)
|
2012-08-10 |
2021-02-17 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
바이러스 감염 또는 추가 질환의 치료를 위한 알킬피리미딘 유도체
|
|
NZ743463A
(en)
|
2012-08-28 |
2019-09-27 |
Janssen Sciences Ireland Uc |
Sulfamoyl-arylamides and the use thereof as medicaments for the treatment of hepatitis b
|
|
AU2013307328B2
(en)
|
2012-08-28 |
2017-10-19 |
Janssen Sciences Ireland Uc |
Fused bicyclic sulfamoyl derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
BR112015004113A2
(pt)
|
2012-09-10 |
2017-07-04 |
Hoffmann La Roche |
6-aminoácido heteroarila diidropirimidinas para o tratamento e profilaxia da infecção pelo vírus da hepatite b
|
|
TR201807076T4
(tr)
|
2012-10-10 |
2018-06-21 |
Janssen Sciences Ireland Uc |
Viral enfeksiyonların ve diğer hastalıkların tedavisine yönelik pirolo[3,2-d]pirimidin derivatları.
|
|
CA2890905A1
(en)
|
2012-11-16 |
2014-05-22 |
Biocryst Pharmaceuticals, Inc. |
Antiviral azasugar-containing nucleosides
|
|
CA2886635C
(en)
|
2012-11-16 |
2021-01-05 |
Janssen Sciences Ireland Uc |
Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections
|
|
AP2015008510A0
(en)
|
2012-12-21 |
2015-06-30 |
Gilead Sciences Inc |
Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
|
|
PE20151063A1
(es)
|
2012-12-27 |
2015-08-03 |
Japan Tobacco Inc |
DERIVADO SUSTITUIDO DE ESPIROPIRIDO[1,2-a]PIRAZINA Y USO MEDICO DEL MISMO COMO INHIBIDOR DE LA INTEGRASA DEL VIH
|
|
WO2014116755A1
(en)
|
2013-01-22 |
2014-07-31 |
Massachusetts Institute Of Technology |
Uses of dihydro bases
|
|
KR102205202B1
(ko)
|
2013-02-01 |
2021-01-21 |
웰스태트 테러퓨틱스 코포레이션 |
항염증, 항진균, 항기생충, 및 항암 활성을 갖는 아민 화합물
|
|
EP2958900B1
(en)
|
2013-02-21 |
2019-04-10 |
Janssen Sciences Ireland Unlimited Company |
2-aminopyrimidine derivatives for the treatment of viral infections
|
|
MX366123B
(es)
|
2013-02-28 |
2019-06-27 |
Janssen Sciences Ireland Uc |
Sulfamoil-arilamidas y el uso de las mismas como medicamentos para el tratamiento de la hepatitis b.
|
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
|
US9266904B2
(en)
|
2013-05-17 |
2016-02-23 |
Hoffmann-La Roche Inc. |
6-bridged heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection
|
|
NO2865735T3
(cg-RX-API-DMAC10.html)
|
2013-07-12 |
2018-07-21 |
|
|
|
PL3252058T3
(pl)
|
2013-07-12 |
2021-07-19 |
Gilead Sciences, Inc. |
Policykliczne związki karbamoilopirydonowe i ich zastosowanie do leczenia infekcji hiv
|
|
CN105492446B
(zh)
|
2013-07-30 |
2018-08-03 |
爱尔兰詹森科学公司 |
用于治疗病毒性感染的噻吩并[3,2-d]嘧啶衍生物
|
|
ES2877050T3
(es)
|
2014-05-01 |
2021-11-16 |
Novartis Ag |
Compuestos y composiciones como agonistas del receptor 7 de tipo toll
|
|
EP3154958B1
(en)
*
|
2014-06-13 |
2020-10-07 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
|
CA2960436C
(en)
|
2014-09-16 |
2021-01-05 |
Gilead Sciences, Inc. |
Solid forms of a toll-like receptor modulator
|
|
MY188211A
(en)
|
2015-03-04 |
2021-11-24 |
Gilead Sciences Inc |
Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
|
|
AU2016322763A1
(en)
|
2015-09-15 |
2018-04-19 |
Gilead Sciences, Inc. |
Modulators of toll-like recptors for the treatment of HIV
|
|
CA3027471A1
(en)
|
2016-07-01 |
2018-01-04 |
Janssen Sciences Ireland Unlimited Company |
Dihydropyranopyrimidines for the treatment of viral infections
|
|
WO2018045150A1
(en)
|
2016-09-02 |
2018-03-08 |
Gilead Sciences, Inc. |
4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
|
|
MA46093A
(fr)
|
2016-09-02 |
2021-05-19 |
Gilead Sciences Inc |
Composés modulateurs du recepteur de type toll
|
|
IL312120B2
(en)
|
2017-06-23 |
2025-06-01 |
Birdie Biopharmaceuticals Inc |
Pharmaceutical compositions
|
|
TWI751516B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI879779B
(zh)
|
2019-06-28 |
2025-04-11 |
美商基利科學股份有限公司 |
類鐸受體調節劑化合物的製備方法
|
|
US20240269142A1
(en)
|
2021-05-13 |
2024-08-15 |
Gilead Sciences, Inc. |
COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS
|