IT1204612B - Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica - Google Patents

Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica

Info

Publication number
IT1204612B
IT1204612B IT20516/87A IT2051687A IT1204612B IT 1204612 B IT1204612 B IT 1204612B IT 20516/87 A IT20516/87 A IT 20516/87A IT 2051687 A IT2051687 A IT 2051687A IT 1204612 B IT1204612 B IT 1204612B
Authority
IT
Italy
Prior art keywords
preparation
pharmaceutical compositions
pteridins
magnesic
activities
Prior art date
Application number
IT20516/87A
Other languages
English (en)
Other versions
IT8720516A0 (it
Inventor
Federico Gennari
Original Assignee
Bioresearch Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Spa filed Critical Bioresearch Spa
Priority to IT20516/87A priority Critical patent/IT1204612B/it
Publication of IT8720516A0 publication Critical patent/IT8720516A0/it
Priority to DE88106141T priority patent/DE3885933T2/de
Priority to ES88106141T priority patent/ES2061543T3/es
Priority to AT88106141T priority patent/ATE97808T1/de
Priority to EP88106141A priority patent/EP0290819B1/en
Priority to JP63115030A priority patent/JP2621925B2/ja
Application granted granted Critical
Publication of IT1204612B publication Critical patent/IT1204612B/it
Priority to US07/488,438 priority patent/US5047405A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT20516/87A 1987-05-14 1987-05-14 Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica IT1204612B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT20516/87A IT1204612B (it) 1987-05-14 1987-05-14 Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica
DE88106141T DE3885933T2 (de) 1987-05-14 1988-04-18 Zur Herstellung pharmazeutischer Zusammensetzungen mit antiamnesischer Wirkung geeignete Pteridine.
ES88106141T ES2061543T3 (es) 1987-05-14 1988-04-18 Pteridinas apropiadas para la preparacion de composiciones farmaceuticas con actividad antiamnesica.
AT88106141T ATE97808T1 (de) 1987-05-14 1988-04-18 Zur herstellung pharmazeutischer zusammensetzungen mit antiamnesischer wirkung geeignete pteridine.
EP88106141A EP0290819B1 (en) 1987-05-14 1988-04-18 Pteridines suitable for the preparation of pharmaceutical compositions with antiamnesic activity
JP63115030A JP2621925B2 (ja) 1987-05-14 1988-05-13 抗健忘症活性をもつ薬剤組成物の製法に適するプテリジン
US07/488,438 US5047405A (en) 1987-05-14 1990-02-27 Antiamnesic use of pteridine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20516/87A IT1204612B (it) 1987-05-14 1987-05-14 Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica

Publications (2)

Publication Number Publication Date
IT8720516A0 IT8720516A0 (it) 1987-05-14
IT1204612B true IT1204612B (it) 1989-03-10

Family

ID=11168110

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20516/87A IT1204612B (it) 1987-05-14 1987-05-14 Pteridine atte alla preparazione di composizioni farmaceutiche ad attivita' antiamnesica

Country Status (7)

Country Link
US (1) US5047405A (it)
EP (1) EP0290819B1 (it)
JP (1) JP2621925B2 (it)
AT (1) ATE97808T1 (it)
DE (1) DE3885933T2 (it)
ES (1) ES2061543T3 (it)
IT (1) IT1204612B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229517B (it) * 1989-01-31 1991-09-03 Bioresearch Spa Impiego di acido 5-metiltetraidrofolico, di acido 5 formiltetraidrofolico, e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato adatte ad essere impiegate nella terapia dei disordini depressivi e composizioni farmaceutiche relative.
IT1229203B (it) * 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
ES2040137T3 (es) * 1990-07-17 1993-10-01 Goldwell Aktiengesellschaft Agente para la tincion del pelo y su empleo.
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
AU1599395A (en) * 1994-01-03 1995-08-01 Cocensys, Inc. 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
DE4418096A1 (de) * 1994-05-24 1995-11-30 Cassella Ag Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase
ATE277929T1 (de) * 1998-12-28 2004-10-15 4 Aza Bioscience Nv Immunsuppressive wirkungen von pteridinderivaten
US7276506B2 (en) * 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
CA2361561A1 (en) * 1999-02-02 2000-08-10 K.U. Leuven Research & Development Immunosurpressive effects of pteridine derivatives
US6946465B2 (en) * 1999-02-02 2005-09-20 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
CA2500952C (en) 2002-10-04 2011-04-26 Prana Biotechnology Limited Neurologically-active compounds
PL1663244T3 (pl) * 2003-09-12 2008-01-31 4 Aza Ip Nv Pochodne pterydyny do leczenia chorób związanych z TNF-alfa
US20070032477A1 (en) * 2003-10-17 2007-02-08 Waer Mark J A Pteridine derivatives useful for making pharmaceutical compositions
AU2007240120A1 (en) 2006-04-14 2007-10-25 Prana Biotechnology Ltd Method of treatment of age-related macular degeneration (AMD)
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
RS56787B1 (sr) 2015-03-04 2018-04-30 Gilead Sciences Inc Toll-like receptor koji modulira jedinjenja 4,6-diamino-pirido[3,2-d]pirimidina
WO2018045150A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
CA3035346A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. Toll like receptor modulator compounds
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2232098A1 (de) * 1972-06-30 1974-01-17 Boehringer Mannheim Gmbh 2-alkyl-4(3h)-pteridinone und verfahren zu ihrer herstellung
US4183934A (en) * 1978-10-16 1980-01-15 Abbott Laboratories 4-Hydroxy-7-(substituted)phenylpteridines
US4550109A (en) * 1984-05-31 1985-10-29 The Board Of Regents, The University Of Texas System Lipoidal biopterin compounds
JPH0699433B2 (ja) * 1985-06-22 1994-12-07 鐘淵化学工業株式会社 ５，６−ジヒドロプテリジン化合物

Also Published As

Publication number Publication date
DE3885933T2 (de) 1994-04-14
ATE97808T1 (de) 1993-12-15
EP0290819B1 (en) 1993-12-01
EP0290819A2 (en) 1988-11-17
IT8720516A0 (it) 1987-05-14
EP0290819A3 (en) 1990-10-10
DE3885933D1 (de) 1994-01-13
JP2621925B2 (ja) 1997-06-18
US5047405A (en) 1991-09-10
JPS63297326A (ja) 1988-12-05
ES2061543T3 (es) 1994-12-16

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