ES2012736A6 - Procedimiento para la preparacion de derivados triciclicos de 3-oxopropanonitrilo. - Google Patents
Procedimiento para la preparacion de derivados triciclicos de 3-oxopropanonitrilo.Info
- Publication number
- ES2012736A6 ES2012736A6 ES8902136A ES8902136A ES2012736A6 ES 2012736 A6 ES2012736 A6 ES 2012736A6 ES 8902136 A ES8902136 A ES 8902136A ES 8902136 A ES8902136 A ES 8902136A ES 2012736 A6 ES2012736 A6 ES 2012736A6
- Authority
- ES
- Spain
- Prior art keywords
- tricyclic
- oxo
- preparation
- group
- propanenitrile derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS TRICICLICOS DE 3-OXOPROPANONITRILO. LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTO DE FORMULA GENERAL (I), QUE POSEEN ACTIVIDAD INMUNOMODULADORA Y SON UTILES, POR EJEMPLO, EN EL TRATAMIENTO DE ENFERMEDADES NEOPLASTICAS Y DE INFECCIONES AGUDAS Y CRONICAS DE ORIGEN BACTERIANO O VIRAL EN MAMIFEROS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888814586A GB8814586D0 (en) | 1988-06-20 | 1988-06-20 | Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2012736A6 true ES2012736A6 (es) | 1990-04-01 |
Family
ID=10638991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8902136A Expired - Fee Related ES2012736A6 (es) | 1988-06-20 | 1989-06-19 | Procedimiento para la preparacion de derivados triciclicos de 3-oxopropanonitrilo. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5166152A (es) |
EP (1) | EP0420883B1 (es) |
JP (1) | JPH03505204A (es) |
KR (1) | KR900701790A (es) |
CN (1) | CN1039026A (es) |
AU (1) | AU3758089A (es) |
CA (1) | CA1337937C (es) |
DE (1) | DE68910523T2 (es) |
DK (1) | DK300990A (es) |
ES (1) | ES2012736A6 (es) |
GB (1) | GB8814586D0 (es) |
GR (1) | GR1000467B (es) |
HU (1) | HUT58739A (es) |
IL (1) | IL90389A (es) |
NZ (1) | NZ229586A (es) |
PT (1) | PT90904B (es) |
WO (1) | WO1989012638A1 (es) |
YU (1) | YU125389A (es) |
ZA (1) | ZA894679B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8814587D0 (en) * | 1988-06-20 | 1988-07-27 | Erba Carlo Spa | Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation |
US5260328A (en) * | 1989-04-06 | 1993-11-09 | Farmitalia Carlo Erba Srl | Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis |
GB8907799D0 (en) * | 1989-04-06 | 1989-05-17 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases |
GB8916290D0 (en) * | 1989-07-17 | 1989-08-31 | Erba Carlo Spa | Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis |
AU6668896A (en) * | 1995-08-31 | 1997-03-19 | Idemitsu Kosan Co. Ltd | Process for producing thiochroman derivatives |
AU7145296A (en) * | 1995-10-04 | 1997-04-28 | Idemitsu Kosan Co. Ltd | Pyrazole derivatives |
GB9720901D0 (en) * | 1997-10-01 | 1997-12-03 | Pharmacia & Upjohn Spa | Condensed benzothiopyranic compounds |
GB9720899D0 (en) * | 1997-10-01 | 1997-12-03 | Pharmacia & Upjohn Spa | Condensed heterocyclic compounds |
AU2010317883B2 (en) * | 2009-11-13 | 2015-08-06 | Merck Serono S.A. | Tricyclic pyrazol amine derivatives |
ES2849434T3 (es) * | 2013-06-24 | 2021-08-18 | Merck Patent Gmbh | Compuestos de pirazol como moduladores del FRSH y usos de los mismos |
CN103626787B (zh) * | 2013-12-10 | 2016-06-15 | 沈阳药科大学 | 噻吩并硫杂类化合物及其应用 |
WO2015196335A1 (en) * | 2014-06-23 | 2015-12-30 | Tocopherx, Inc. | Pyrazole compounds as modulators of fshr and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2009079A1 (es) * | 1968-05-22 | 1970-01-30 | Sandoz Sa | |
US4268516A (en) * | 1978-10-11 | 1981-05-19 | Pfizer Inc. | [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents |
US4816467A (en) * | 1987-01-09 | 1989-03-28 | Farmitalia Carlo Erba S.R.L | Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use |
CA1311761C (en) * | 1987-04-09 | 1992-12-22 | E.I. Du Pont De Nemours And Company | Insecticidal substituted indazoles |
GB2227741B (en) * | 1989-02-06 | 1992-08-05 | Erba Carlo Spa | Condensed 3-oxo-propanenitrile derivatives and process for their preparation |
-
1988
- 1988-06-20 GB GB888814586A patent/GB8814586D0/en active Pending
-
1989
- 1989-05-23 IL IL90389A patent/IL90389A/xx unknown
- 1989-06-02 GR GR890100371A patent/GR1000467B/el unknown
- 1989-06-08 CA CA000602094A patent/CA1337937C/en not_active Expired - Fee Related
- 1989-06-16 HU HU893875A patent/HUT58739A/hu unknown
- 1989-06-16 JP JP1506441A patent/JPH03505204A/ja active Pending
- 1989-06-16 NZ NZ229586A patent/NZ229586A/en unknown
- 1989-06-16 DE DE89906767T patent/DE68910523T2/de not_active Expired - Fee Related
- 1989-06-16 EP EP89906767A patent/EP0420883B1/en not_active Expired - Lifetime
- 1989-06-16 WO PCT/EP1989/000683 patent/WO1989012638A1/en active IP Right Grant
- 1989-06-16 AU AU37580/89A patent/AU3758089A/en not_active Abandoned
- 1989-06-16 KR KR1019900700336A patent/KR900701790A/ko not_active Application Discontinuation
- 1989-06-19 YU YU01253/89A patent/YU125389A/xx unknown
- 1989-06-19 ES ES8902136A patent/ES2012736A6/es not_active Expired - Fee Related
- 1989-06-19 CN CN89106283A patent/CN1039026A/zh active Pending
- 1989-06-19 PT PT90904A patent/PT90904B/pt not_active IP Right Cessation
- 1989-06-20 US US07/635,158 patent/US5166152A/en not_active Expired - Fee Related
- 1989-06-20 ZA ZA894679A patent/ZA894679B/xx unknown
-
1990
- 1990-12-19 DK DK300990A patent/DK300990A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB8814586D0 (en) | 1988-07-27 |
IL90389A0 (en) | 1990-01-18 |
DK300990A (da) | 1991-02-20 |
WO1989012638A1 (en) | 1989-12-28 |
GR1000467B (el) | 1992-07-30 |
DE68910523T2 (de) | 1994-04-07 |
GR890100371A (en) | 1990-05-11 |
EP0420883A1 (en) | 1991-04-10 |
HU893875D0 (en) | 1991-07-29 |
NZ229586A (en) | 1991-07-26 |
AU3758089A (en) | 1990-01-12 |
US5166152A (en) | 1992-11-24 |
HUT58739A (en) | 1992-03-30 |
DK300990D0 (da) | 1990-12-19 |
YU125389A (en) | 1991-02-28 |
CN1039026A (zh) | 1990-01-24 |
JPH03505204A (ja) | 1991-11-14 |
PT90904A (pt) | 1989-12-29 |
KR900701790A (ko) | 1990-12-04 |
IL90389A (en) | 1992-12-01 |
ZA894679B (en) | 1991-02-27 |
DE68910523D1 (de) | 1993-12-09 |
EP0420883B1 (en) | 1993-11-03 |
CA1337937C (en) | 1996-01-16 |
PT90904B (pt) | 1994-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20040503 |