ZA894679B - Tricyclic 3-oxo-propanenitrile derivatives and process for their preparation - Google Patents

Tricyclic 3-oxo-propanenitrile derivatives and process for their preparation

Info

Publication number
ZA894679B
ZA894679B ZA894679A ZA894679A ZA894679B ZA 894679 B ZA894679 B ZA 894679B ZA 894679 A ZA894679 A ZA 894679A ZA 894679 A ZA894679 A ZA 894679A ZA 894679 B ZA894679 B ZA 894679B
Authority
ZA
South Africa
Prior art keywords
tricyclic
oxo
preparation
propanenitrile derivatives
propanenitrile
Prior art date
Application number
ZA894679A
Other languages
English (en)
Inventor
Gianfederico Doria
Doria Gianfederico
Anna Maria Isetta
Maria Isetta Anna
Mario Ferrari
Ferrari Mario
Domenico Trizio
Trizio Domenico
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA894679B publication Critical patent/ZA894679B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA894679A 1988-06-20 1989-06-20 Tricyclic 3-oxo-propanenitrile derivatives and process for their preparation ZA894679B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888814586A GB8814586D0 (en) 1988-06-20 1988-06-20 Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation

Publications (1)

Publication Number Publication Date
ZA894679B true ZA894679B (en) 1991-02-27

Family

ID=10638991

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894679A ZA894679B (en) 1988-06-20 1989-06-20 Tricyclic 3-oxo-propanenitrile derivatives and process for their preparation

Country Status (19)

Country Link
US (1) US5166152A (es)
EP (1) EP0420883B1 (es)
JP (1) JPH03505204A (es)
KR (1) KR900701790A (es)
CN (1) CN1039026A (es)
AU (1) AU3758089A (es)
CA (1) CA1337937C (es)
DE (1) DE68910523T2 (es)
DK (1) DK300990A (es)
ES (1) ES2012736A6 (es)
GB (1) GB8814586D0 (es)
GR (1) GR1000467B (es)
HU (1) HUT58739A (es)
IL (1) IL90389A (es)
NZ (1) NZ229586A (es)
PT (1) PT90904B (es)
WO (1) WO1989012638A1 (es)
YU (1) YU125389A (es)
ZA (1) ZA894679B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
US5260328A (en) * 1989-04-06 1993-11-09 Farmitalia Carlo Erba Srl Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis
GB8907799D0 (en) * 1989-04-06 1989-05-17 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
GB8916290D0 (en) * 1989-07-17 1989-08-31 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis
WO1997008163A1 (fr) * 1995-08-31 1997-03-06 Idemitsu Kosan Co., Ltd. Procede de production de derives thiochromane
AU7145296A (en) * 1995-10-04 1997-04-28 Idemitsu Kosan Co. Ltd Pyrazole derivatives
GB9720899D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
GB9720901D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed benzothiopyranic compounds
CA2778174C (en) * 2009-11-13 2018-02-20 Merck Serono S.A. Tricyclic pyrazol amine derivatives as pi3k inhibitors
JP6625973B2 (ja) 2013-06-24 2019-12-25 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ Ｆｓｈｒの調節剤としてのピラゾール化合物及びその使用
CN103626787B (zh) * 2013-12-10 2016-06-15 沈阳药科大学 噻吩并硫杂类化合物及其应用
WO2015196335A1 (en) * 2014-06-23 2015-12-30 Tocopherx, Inc. Pyrazole compounds as modulators of fshr and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2009079A1 (es) * 1968-05-22 1970-01-30 Sandoz Sa
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
US4816467A (en) * 1987-01-09 1989-03-28 Farmitalia Carlo Erba S.R.L Heteroaryl 3-oxo-propanenitrile derivatives, pharmaceutical compositions and use
AU609808B2 (en) * 1987-04-09 1991-05-09 E.I. Du Pont De Nemours And Company Insecticidal substituted indazoles
GB2227741B (en) * 1989-02-06 1992-08-05 Erba Carlo Spa Condensed 3-oxo-propanenitrile derivatives and process for their preparation

Also Published As

Publication number Publication date
WO1989012638A1 (en) 1989-12-28
DE68910523T2 (de) 1994-04-07
PT90904A (pt) 1989-12-29
GR890100371A (en) 1990-05-11
YU125389A (en) 1991-02-28
CN1039026A (zh) 1990-01-24
IL90389A0 (en) 1990-01-18
NZ229586A (en) 1991-07-26
ES2012736A6 (es) 1990-04-01
DK300990D0 (da) 1990-12-19
IL90389A (en) 1992-12-01
HUT58739A (en) 1992-03-30
PT90904B (pt) 1994-12-30
CA1337937C (en) 1996-01-16
US5166152A (en) 1992-11-24
EP0420883A1 (en) 1991-04-10
KR900701790A (ko) 1990-12-04
HU893875D0 (en) 1991-07-29
AU3758089A (en) 1990-01-12
GB8814586D0 (en) 1988-07-27
DE68910523D1 (de) 1993-12-09
GR1000467B (el) 1992-07-30
DK300990A (da) 1991-02-20
JPH03505204A (ja) 1991-11-14
EP0420883B1 (en) 1993-11-03

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