|
GB8626413D0
(en)
|
1986-11-05 |
1986-12-03 |
Gilliland L K |
Antibodies
|
|
GB8626412D0
(en)
|
1986-11-05 |
1986-12-03 |
Clark M R |
Antibodies
|
|
WO1990002569A1
(en)
|
1988-09-06 |
1990-03-22 |
International Genetic Engineering, Inc. |
Production of chimeric mouse-human antibodies with specificity to human tumor antigens
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
WO1991000906A1
(en)
|
1989-07-12 |
1991-01-24 |
Genetics Institute, Inc. |
Chimeric and transgenic animals capable of producing human antibodies
|
|
US5574205A
(en)
|
1989-07-25 |
1996-11-12 |
Cell Genesys |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
WO1991008216A1
(en)
|
1989-12-01 |
1991-06-13 |
Genpharm International, Inc. |
Production of recombinant polypeptides by bovine species and transgenic methods
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6657103B1
(en)
|
1990-01-12 |
2003-12-02 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
CA2050918A1
(en)
|
1990-01-12 |
1991-07-13 |
Raju Kucherlapati |
Generation of xenogeneic antibodies
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US7041871B1
(en)
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69133476T2
(de)
|
1990-08-29 |
2006-01-05 |
GenPharm International, Inc., Palo Alto |
Transgene Mäuse fähig zur Produktion heterologer Antikörper
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
WO1994025585A1
(en)
|
1993-04-26 |
1994-11-10 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
US7067284B1
(en)
|
1992-01-27 |
2006-06-27 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
SG48760A1
(en)
|
1992-07-24 |
2003-03-18 |
Abgenix Inc |
Generation of xenogenetic antibodies
|
|
JPH08500017A
(ja)
|
1992-08-17 |
1996-01-09 |
ジェネンテク，インコーポレイテッド |
二特異的免疫アドヘジン
|
|
HUT71790A
(en)
|
1992-12-01 |
1996-02-28 |
Protein Design Labs |
Humanized antibodies reactive with l-selectin
|
|
GB9308271D0
(en)
|
1993-04-21 |
1993-06-02 |
Univ Edinburgh |
Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
|
|
US5877396A
(en)
|
1993-04-23 |
1999-03-02 |
Sloan Kettering Institute For Cancer Research |
Mice mutant for functional Fc receptors and method of treating autoimmune diseases
|
|
US5693506A
(en)
|
1993-11-16 |
1997-12-02 |
The Regents Of The University Of California |
Process for protein production in plants
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
WO1995017500A1
(en)
|
1993-12-23 |
1995-06-29 |
Abs Global, Inc. |
Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals
|
|
GB9401380D0
(en)
|
1994-01-25 |
1994-03-23 |
Pharmaceutical Proteins Ltd |
Embryonic cell isolation
|
|
EP1231268B1
(en)
|
1994-01-31 |
2005-07-27 |
Trustees Of Boston University |
Polyclonal antibody libraries
|
|
US7119248B1
(en)
|
1994-04-12 |
2006-10-10 |
Miltenyi Biotec Gmbh |
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
|
|
US6080560A
(en)
|
1994-07-25 |
2000-06-27 |
Monsanto Company |
Method for producing antibodies in plant cells
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
WO1997032603A1
(en)
|
1996-03-05 |
1997-09-12 |
The Scripps Research Institute |
Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens
|
|
DK0826696T3
(da)
|
1996-09-03 |
2002-09-23 |
Gsf Forschungszentrum Umwelt |
Anvendelse af bi- og trispecifikke antistoffer til inducering af en tumorimmunitet
|
|
DK1500329T3
(da)
|
1996-12-03 |
2012-07-09 |
Amgen Fremont Inc |
Humane antistoffer, der specifikt binder TNF-alfa
|
|
WO1998039416A1
(en)
|
1997-03-06 |
1998-09-11 |
Infigen, Inc. |
Method of cloning animals
|
|
CN1203922A
(zh)
|
1997-03-21 |
1999-01-06 |
三共株式会社 |
人源化抗人fas抗体
|
|
WO1998046645A2
(en)
|
1997-04-14 |
1998-10-22 |
Micromet Gesellschaft Für Biomedizinische Forschung Mbh |
Method for the production of antihuman antigen receptors and uses thereof
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
AU751659B2
(en)
|
1997-05-02 |
2002-08-22 |
Genentech Inc. |
A method for making multispecific antibodies having heteromultimeric and common components
|
|
US6774279B2
(en)
|
1997-05-30 |
2004-08-10 |
Carnegie Institution Of Washington |
Use of FLP recombinase in mice
|
|
NZ503489A
(en)
|
1997-10-03 |
2002-11-26 |
Chugai Pharmaceutical Co Ltd |
Natural humanized antibody, method of production and pharmaceutical composition
|
|
AU760113C
(en)
|
1997-11-18 |
2004-04-22 |
Pioneer Hi-Bred International, Inc. |
Compositions and methods for genetic modification of plants
|
|
GB9823930D0
(en)
|
1998-11-03 |
1998-12-30 |
Babraham Inst |
Murine expression of human ig\ locus
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
RU10506U1
(ru)
|
1999-04-08 |
1999-08-16 |
Кривулин Виталий Николаевич |
Ручной культиватор
|
|
CA2370477C
(en)
|
1999-04-15 |
2010-06-29 |
Crucell Holland B.V. |
Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein
|
|
EP1183344A4
(en)
|
1999-05-27 |
2003-06-25 |
Human Genome Sciences Inc |
ADAM POLYNUCLEOTIDES AND POLYPEPTIDES
|
|
GB0001448D0
(en)
|
2000-01-21 |
2000-03-08 |
Novartis Ag |
Organic compounds
|
|
CA2401965A1
(en)
|
2000-02-29 |
2001-09-07 |
Auburn University |
Production of antibodies in transgenic plastids
|
|
CN101498731A
(zh)
|
2000-05-18 |
2009-08-05 |
日本烟草产业株式会社 |
抗协同刺激信号转导分子ailim的人单克隆抗体及其药物用途
|
|
CA2409991A1
(en)
|
2000-05-24 |
2001-11-29 |
Imclone Systems Incorporated |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
|
JP2004504055A
(ja)
|
2000-07-21 |
2004-02-12 |
アメリカ合衆国 |
真核生物ゲノムにおけるｄｎａの置換、転座およびスタッキングの方法
|
|
CA2422155A1
(en)
|
2000-08-03 |
2002-02-14 |
Wim Van Schooten |
Production of humanized antibodies in transgenic animals
|
|
EP1184458A1
(en)
|
2000-08-28 |
2002-03-06 |
U-BISys B.V. |
Differentially expressed CD46 epitopes, proteinaceous molecules capable of binding thereto, and uses thereof
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US7105348B2
(en)
|
2000-10-31 |
2006-09-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6586251B2
(en)
|
2000-10-31 |
2003-07-01 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US7449179B2
(en)
|
2000-11-16 |
2008-11-11 |
Cornell Research Foundation, Inc. |
Vectors for conditional gene inactivation
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
DE10064750A1
(de)
|
2000-12-22 |
2002-06-27 |
Bayer Ag |
Verfahren zur Herstellung von 1,6-Hexandiolen
|
|
JP2004531217A
(ja)
|
2001-01-05 |
2004-10-14 |
ファイザー・インク |
インスリン様成長因子ｉ受容体に対する抗体
|
|
US6961875B2
(en)
|
2001-03-22 |
2005-11-01 |
International Business Machines Corporation |
Method and apparatus for capturing event traces for debug and analysis
|
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
|
US7034134B2
(en)
|
2001-04-26 |
2006-04-25 |
Bristol-Myers Squibb Company |
Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
|
|
US7074611B2
(en)
|
2001-04-27 |
2006-07-11 |
Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) |
Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof
|
|
CN100448992C
(zh)
|
2001-05-11 |
2009-01-07 |
麒麟医药株式会社 |
含人抗体λ轻链基因的人类人工染色体
|
|
JP4303105B2
(ja)
|
2001-06-28 |
2009-07-29 |
ドマンティス リミテッド |
二重特異性リガンドとその利用
|
|
EP2298809A3
(en)
|
2001-07-12 |
2012-02-15 |
FOOTE, Jefferson |
Super humanized antibodies
|
|
CA2898314A1
(en)
|
2001-07-19 |
2003-07-31 |
Perian Therapeutics, Inc. |
Multimeric proteins and methods of making and using same
|
|
ATE476504T1
(de)
|
2001-10-01 |
2010-08-15 |
Deutsches Krebsforsch |
Verfahren zur herstellung von protein- bibliotheken und zur selektion von proteinen daraus
|
|
US20060199204A1
(en)
|
2001-10-05 |
2006-09-07 |
U.S. Epa |
Genetic testing for male factor infertility
|
|
WO2003031656A1
(en)
|
2001-10-05 |
2003-04-17 |
United States Environmental Protection Agency |
Genetic testing for male factor infertility
|
|
EP1461442B1
(en)
|
2001-11-30 |
2017-09-06 |
Amgen Fremont Inc. |
Transgenic animals bearing human ig lambda light chain genes
|
|
GB0130267D0
(en)
|
2001-12-19 |
2002-02-06 |
Neutec Pharma Plc |
Focussed antibody technology
|
|
US20050095712A1
(en)
|
2002-01-17 |
2005-05-05 |
Alberto Martin |
Mutations caused by activation-induced cytidine deaminase
|
|
AU2003201093A1
(en)
|
2002-01-18 |
2003-07-30 |
Inovio As |
Bispecific antibody dna constructs for intramuscular administration
|
|
EP1505148B1
(en)
|
2002-04-26 |
2009-04-15 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of screening for agonistic antibodies
|
|
US20040023880A1
(en)
|
2002-05-03 |
2004-02-05 |
Gale Nicholas W. |
Methods of inducing formation of functional and organized lymphatic vessels
|
|
AU2003277087B2
(en)
|
2002-06-14 |
2008-07-31 |
Immunomedics, Inc. |
Humanized monoclonal antiboby hPAM4
|
|
CN101962408A
(zh)
|
2002-07-12 |
2011-02-02 |
杰斐逊·富特 |
超人源化抗体
|
|
PT2314629E
(pt)
|
2002-07-18 |
2014-01-22 |
Merus B V |
Produção recombinante de misturas de anticorpos
|
|
AR042145A1
(es)
|
2002-11-27 |
2005-06-08 |
Dow Agrociences Llc |
Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
|
|
GB0228210D0
(en)
|
2002-12-03 |
2003-01-08 |
Babraham Inst |
Single chain antibodies
|
|
GB0230201D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
EP1439234A1
(en)
|
2003-01-08 |
2004-07-21 |
ARTEMIS Pharmaceuticals GmbH |
Targeted transgenesis using the rosa26 locus
|
|
JP4477579B2
(ja)
|
2003-01-21 |
2010-06-09 |
中外製薬株式会社 |
抗体の軽鎖スクリーニング方法
|
|
CA2514417A1
(en)
|
2003-01-28 |
2004-08-12 |
Cellectis |
Custom-made meganuclease and use thereof
|
|
JP2006520610A
(ja)
|
2003-03-04 |
2006-09-14 |
アレクシオン ファーマシューティカルズ， インコーポレイテッド |
ハイブリッド不変領域を産生するのに用いるベクター
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
WO2005001087A2
(en)
|
2003-06-11 |
2005-01-06 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying genes in eukaryotic cells
|
|
EP1644417B1
(en)
|
2003-07-15 |
2014-04-30 |
Therapeutic Human Polyclonals, Inc. |
Humanized immunoglobulin loci
|
|
WO2005019463A1
(en)
|
2003-08-11 |
2005-03-03 |
Therapeutic Human Polyclonals, Inc. |
Improved transgenesis with humanized immunoglobulin loci
|
|
RU2251699C1
(ru)
|
2003-09-25 |
2005-05-10 |
Киселев Всеволод Иванович |
Способ ранней и доклинической диагностики цервикального рака
|
|
WO2005038001A2
(en)
|
2003-10-14 |
2005-04-28 |
Therapeutic Human Polyclonals, Inc. |
Improved transgenesis by sperm-mediated gene transfer
|
|
ES2364147T3
(es)
|
2004-01-16 |
2011-08-25 |
Regeneron Pharmaceuticals, Inc. |
Polipéptidos de fusión capaces de activar receptores.
|
|
WO2005078098A1
(en)
|
2004-02-12 |
2005-08-25 |
The Walter And Eliza Hall Institute Of Medical Research |
Modified cells that co-express blimp1 and a reporter molecule and methods of using the same
|
|
CN1560081A
(zh)
|
2004-02-17 |
2005-01-05 |
大连帝恩生物工程有限公司 |
用能产生人IgGl重链－κ轻链小鼠作为制备人源化单克隆抗体和应用
|
|
US7625549B2
(en)
|
2004-03-19 |
2009-12-01 |
Amgen Fremont Inc. |
Determining the risk of human anti-human antibodies in transgenic mice
|
|
DK2767161T3
(en)
|
2004-10-19 |
2018-05-07 |
Regeneron Pharma |
Method of generating an animal homozygous for genetic modification
|
|
WO2006047367A2
(en)
|
2004-10-22 |
2006-05-04 |
Therapeutic Human Polyclonals, Inc. |
Suppression of endogenous immunoglubolin expression in non-human transgenic animals
|
|
AU2005333602B2
(en)
*
|
2004-10-22 |
2012-04-12 |
Medimmune, Llc |
High affinity antibodies against HMGB1 and methods of use thereof
|
|
CA2589208A1
(en)
|
2004-11-26 |
2006-06-01 |
Frankgen Biotechnologie Ag |
Gene trap cassettes for random and targeted conditional gene inactivation
|
|
EP1662005A1
(en)
|
2004-11-26 |
2006-05-31 |
FrankGen Biotechnologie AG |
Enhancer-containing gene trap vectors for random and targeted gene trapping
|
|
US20110041370A1
(en)
|
2005-04-21 |
2011-02-24 |
Saint Andre M |
Face sheet, identification band, and related methods
|
|
US20080196112A1
(en)
|
2005-04-29 |
2008-08-14 |
Innate Pharma, S.A. |
Transgenic Animals and Methods of Making Recombinant Antibodies
|
|
JP2008545375A
(ja)
|
2005-05-14 |
2008-12-18 |
フダン ユニバーシテイ |
脊椎動物の遺伝子操作および解析のための手段としてのｐｉｇｇｙＢａｃ
|
|
KR20130114758A
(ko)
|
2005-05-27 |
2013-10-17 |
오스페달레 산 라파엘 에스.알.엘. |
Ｍｉ-ｒｎａ를 포함하는 유전자 벡터
|
|
PL1739691T3
(pl)
|
2005-06-30 |
2009-06-30 |
Borealis Tech Oy |
Zewnętrzne osłony dla kabli elektroenergetycznych lub telekomunikacyjnych
|
|
FR2888850B1
(fr)
|
2005-07-22 |
2013-01-11 |
Pf Medicament |
Nouveaux anticorps anti-igf-ir et leurs applications
|
|
WO2007065433A2
(en)
|
2005-12-05 |
2007-06-14 |
Symphogen A/S |
Anti-orthopoxvirus recombinant polyclonal antibody
|
|
EP1991580A2
(en)
|
2006-01-25 |
2008-11-19 |
Erasmus University Medical Center Rotterdam |
Generation of heavy-chain only antibodies in transgenic animals
|
|
GB2434578A
(en)
|
2006-01-26 |
2007-08-01 |
Univ Basel |
Transgenic animals
|
|
US7462759B2
(en)
|
2006-02-03 |
2008-12-09 |
Pioneer Hi-Bred International, Inc. |
Brittle stalk 2 gene family and related methods and uses
|
|
GB0615327D0
(en)
|
2006-03-30 |
2006-09-13 |
Univ Edinburgh |
Culture medium containing kinase inhibitors and uses thereof
|
|
JP5514539B2
(ja)
|
2006-03-31 |
2014-06-04 |
メダレックス・リミテッド・ライアビリティ・カンパニー |
ヒト抗体の調製に用いるためのキメラ抗体を発現するトランスジェニック動物
|
|
JP5307708B2
(ja)
|
2006-06-02 |
2013-10-02 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ヒトｉｌ−６受容体に対する高親和性抗体
|
|
WO2007149246A2
(en)
|
2006-06-12 |
2007-12-27 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
JP2010501165A
(ja)
|
2006-08-22 |
2010-01-21 |
ジーツー インフラメイション プロプライエタリー リミテッド |
抗体の作製方法
|
|
ATE536374T1
(de)
|
2006-09-01 |
2011-12-15 |
Therapeutic Human Polyclonals Inc |
Erhöhte expression von humanem oder humanisiertem immunglobulin bei nicht-humanen transgenen tieren
|
|
CA2664343C
(en)
|
2006-10-02 |
2016-04-26 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human il-4 receptor
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
RU2448979C2
(ru)
|
2006-12-14 |
2012-04-27 |
Ридженерон Фармасьютикалз, Инк. |
Антитела человека к дельта-подобному лиганду-4 человека
|
|
GB0700194D0
(en)
|
2007-01-05 |
2007-02-14 |
Univ Edinburgh |
Humanisation of animals
|
|
WO2008112226A2
(en)
|
2007-03-13 |
2008-09-18 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
CN101688228B
(zh)
|
2007-03-13 |
2014-12-24 |
国家犾太健康中心 |
抗体产生的方法
|
|
GB0706628D0
(en)
|
2007-04-04 |
2007-05-16 |
Univ Erasmus |
Germ-line manipulation 1
|
|
EP2336329B8
(en)
|
2007-06-01 |
2012-11-21 |
Omt, Inc. |
Compositions and methods for inhibiting endogenous immunoglobulin genes and producing transgenis human idiotype antibodies
|
|
WO2009013620A2
(en)
|
2007-06-11 |
2009-01-29 |
Erasmus University Medical Center Rotterdam |
Homologous recombination
|
|
ITMI20071522A1
(it)
|
2007-07-27 |
2009-01-28 |
Areta Internat S R L |
Vaccino idiotipico
|
|
EP2185692A4
(en)
|
2007-08-10 |
2012-05-02 |
Medarex Inc |
HCO32 AND HCO27 AND RELATED EXAMPLES
|
|
WO2009023270A2
(en)
|
2007-08-15 |
2009-02-19 |
Amunix, Inc. |
Compositions and methods for modifying properties of biologically active polypeptides
|
|
US8426565B2
(en)
|
2007-08-30 |
2013-04-23 |
Walter And Eliza Hall Institute Of Medical Research |
Dendritic cell marker and uses thereof
|
|
EP3753947A1
(en)
|
2007-09-14 |
2020-12-23 |
Adimab, LLC |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
WO2009051974A1
(en)
|
2007-10-17 |
2009-04-23 |
Nuvelo, Inc. |
Antibodes to cll-1
|
|
US7659842B2
(en)
|
2007-10-24 |
2010-02-09 |
Infineon Technologies Ag |
Quantization error reduction in PWM full-MASH converters
|
|
CN105001333B
(zh)
|
2007-12-14 |
2019-05-17 |
诺沃—诺迪斯克有限公司 |
抗人nkg2d抗体及其用途
|
|
AU2009204501B2
(en)
|
2008-01-07 |
2015-02-12 |
Amgen Inc. |
Method for making antibody Fc-heterodimeric molecules using electrostatic steering effects
|
|
US20090271884A1
(en)
|
2008-03-07 |
2009-10-29 |
Regeneron Pharmaceuticals, Inc. |
ES Cell-Derived Mice From Diploid Host Embryo Injection
|
|
WO2009129247A2
(en)
|
2008-04-14 |
2009-10-22 |
Innovative Targeting Solutions Inc. |
Sequence diversity generation in immunoglobulins
|
|
EP2669298A3
(en)
|
2008-05-23 |
2014-02-26 |
Ablexis, LLC |
Single variable immunoglobulin domain comprising VL-DH-JL
|
|
HUE057994T2
(hu)
|
2008-06-27 |
2022-06-28 |
Merus Nv |
Antitesttermelõ, transzgenikus, egérfélékhez tartozó állat
|
|
LT2346994T
(lt)
|
2008-09-30 |
2022-03-10 |
Ablexis, Llc |
Knock-in pelė, skirta chimerinių antikūnų gamybai
|
|
JP2012508017A
(ja)
|
2008-11-07 |
2012-04-05 |
ファブラス エルエルシー |
抗ｄｌｌ４抗体及びその使用
|
|
US8497325B2
(en)
|
2008-12-15 |
2013-07-30 |
Exxonmobil Chemical Patents Inc. |
Thermoplastic polyolefin blends and films therefrom
|
|
MX2011007660A
(es)
|
2008-12-18 |
2011-08-17 |
Kingdon Craig R |
Animales transgenicos no humanos que expresan anticuerpos humanizados y usos de los mismos.
|
|
JP2012518398A
(ja)
|
2009-02-24 |
2012-08-16 |
グラクソ グループ リミテッド |
抗原結合性構築物
|
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
|
EP2427357B1
(en)
|
2009-05-07 |
2019-02-20 |
Volvo Construction Equipment AB |
A working machine and a method for operating a working machine
|
|
CN102449149B
(zh)
|
2009-05-29 |
2014-04-23 |
莫佛塞斯公司 |
集合及其使用方法
|
|
KR102010827B1
(ko)
|
2009-06-26 |
2019-08-14 |
리제너론 파마슈티칼스 인코포레이티드 |
천연 면역글로불린 포맷을 가지는 용이하게 분리된 이중특이성 항체
|
|
PT2564695E
(pt)
|
2009-07-08 |
2015-06-03 |
Kymab Ltd |
Modelos animais e moléculas terapêuticas
|
|
RU2425880C2
(ru)
*
|
2009-07-30 |
2011-08-10 |
Учреждение Российской академии наук Институт общей генетики им. Н.И. Вавилова РАН |
Способ получения трансгенных мышей
|
|
NZ600002A
(en)
|
2009-11-17 |
2014-08-29 |
Sanford Applied Biosciences L L C |
Human artificial chromosome vector
|
|
MY172472A
(en)
|
2009-12-10 |
2019-11-26 |
Regeneron Pharma |
Mice that make heavy chain antibodies
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
CA2789154C
(en)
*
|
2010-02-08 |
2024-06-11 |
Regeneron Pharmaceuticals, Inc. |
Common light chain mouse
|
|
US20130185821A1
(en)
|
2010-02-08 |
2013-07-18 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US20120021409A1
(en)
|
2010-02-08 |
2012-01-26 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
EP2569337A1
(en)
|
2010-05-14 |
2013-03-20 |
Rinat Neuroscience Corp. |
Heterodimeric proteins and methods for producing and purifying them
|
|
CN103228130B
(zh)
|
2010-06-17 |
2016-03-16 |
科马布有限公司 |
动物模型及治疗分子
|
|
ME03386B
(me)
|
2010-06-22 |
2020-01-20 |
Regeneron Pharma |
Hibridni laki lanac imunoglobulina koji ispoljavaju miševi
|
|
RU2612903C2
(ru)
|
2010-08-02 |
2017-03-13 |
Ридженерон Фармасьютикалз, Инк. |
Мыши, у которых вырабатываются связывающие белки, содержащие vl-домены
|
|
EP2638155A1
(en)
|
2010-11-08 |
2013-09-18 |
Kymab Limited |
Cells & vertebrates for enhanced somatic hypermutation and class switch recombination
|
|
PL4067496T3
(pl)
|
2011-02-25 |
2023-07-31 |
Regeneron Pharmaceuticals, Inc. |
Myszy adam6
|
|
RS66089B1
(sr)
|
2011-08-05 |
2024-11-29 |
Regeneron Pharma |
Humanizovani miševi univerzalnog lakog lanca
|
|
US20130044257A1
(en)
|
2011-08-18 |
2013-02-21 |
Lattice Energy Technology Corporation |
Mobile device with side-mounted camera module
|
|
EP3839049A3
(en)
|
2011-09-19 |
2021-10-20 |
Kymab Limited |
Antibodies, variable domains & chains tailored for human use
|
|
JP2014531452A
(ja)
|
2011-09-19 |
2014-11-27 |
カイマブ・リミテッド |
動物、レパートリーおよび方法
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
EP2761008A1
(en)
|
2011-09-26 |
2014-08-06 |
Kymab Limited |
Chimaeric surrogate light chains (slc) comprising human vpreb
|
|
RU2743589C2
(ru)
|
2011-10-17 |
2021-02-20 |
Регенерон Фармасьютикалс, Инк. |
Мыши с ограниченной тяжелой цепью иммуноглобулина
|
|
GB2496375A
(en)
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
|
US9253965B2
(en)
|
2012-03-28 |
2016-02-09 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
SI2793567T1
(sl)
|
2011-12-20 |
2019-05-31 |
Regeneron Pharmaceuticals, Inc. |
Humanizirane lahkoverižne miši
|
|
HRP20192218T1
(hr)
|
2012-02-01 |
2020-03-06 |
Regeneron Pharmaceuticals, Inc. |
Humanizirani miševi koji izražavaju teške lance koji sadrže vl domene
|
|
PT2838918T
(pt)
|
2012-04-20 |
2019-08-23 |
Merus Nv |
Métodos e meios para a produção de moléculas heterrodiméricas do tipo ig
|
|
JP2015519076A
(ja)
|
2012-06-12 |
2015-07-09 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
限定された免疫グロブリン重鎖遺伝子座を有するヒト化非ヒト動物
|
|
KR20150126863A
(ko)
|
2013-03-13 |
2015-11-13 |
리제너론 파마슈티칼스 인코포레이티드 |
공통 경쇄 마우스
|
|
EP2967013B1
(en)
|
2013-03-13 |
2019-01-16 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|