|
GB8626413D0
(en)
|
1986-11-05 |
1986-12-03 |
Gilliland L K |
Antibodies
|
|
GB8626412D0
(en)
|
1986-11-05 |
1986-12-03 |
Clark M R |
Antibodies
|
|
EP0967277A3
(en)
|
1988-09-06 |
2003-10-15 |
Xoma Corporation |
Production of chimeric mouse-human antibodies with specificity to human tumor antigens
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
WO1991000906A1
(en)
|
1989-07-12 |
1991-01-24 |
Genetics Institute, Inc. |
Chimeric and transgenic animals capable of producing human antibodies
|
|
US5574205A
(en)
|
1989-07-25 |
1996-11-12 |
Cell Genesys |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
ATE140027T1
(de)
|
1989-12-01 |
1996-07-15 |
Pharming Bv |
Herstellung rekombinanter polypeptide durch rinder und transgene methoden
|
|
US6657103B1
(en)
|
1990-01-12 |
2003-12-02 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
ES2284161T3
(es)
|
1990-01-12 |
2007-11-01 |
Amgen Fremont Inc. |
Generacion de anticuerpos xenogenicos.
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
US7041871B1
(en)
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
AU8507191A
(en)
|
1990-08-29 |
1992-03-30 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US7067284B1
(en)
|
1992-01-27 |
2006-06-27 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
ES2301158T3
(es)
|
1992-07-24 |
2008-06-16 |
Amgen Fremont Inc. |
Produccion de anticuerpos xenogenicos.
|
|
EP0656064B1
(en)
|
1992-08-17 |
1997-03-05 |
Genentech, Inc. |
Bispecific immunoadhesins
|
|
CA2149025A1
(en)
|
1992-12-01 |
1994-06-09 |
Man Sung Co |
Humanized antibodies reactive with l-selectin
|
|
GB9308271D0
(en)
|
1993-04-21 |
1993-06-02 |
Univ Edinburgh |
Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
|
|
US5877396A
(en)
|
1993-04-23 |
1999-03-02 |
Sloan Kettering Institute For Cancer Research |
Mice mutant for functional Fc receptors and method of treating autoimmune diseases
|
|
AU6819494A
(en)
|
1993-04-26 |
1994-11-21 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5693506A
(en)
|
1993-11-16 |
1997-12-02 |
The Regents Of The University Of California |
Process for protein production in plants
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
AU1595195A
(en)
|
1993-12-23 |
1995-07-10 |
Abs Global, Inc. |
Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals
|
|
GB9401380D0
(en)
|
1994-01-25 |
1994-03-23 |
Pharmaceutical Proteins Ltd |
Embryonic cell isolation
|
|
PT744958E
(pt)
|
1994-01-31 |
2003-11-28 |
Univ Boston |
Bancos de anticorpos policlonais
|
|
US7119248B1
(en)
|
1994-04-12 |
2006-10-10 |
Miltenyi Biotec Gmbh |
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
|
|
US6080560A
(en)
|
1994-07-25 |
2000-06-27 |
Monsanto Company |
Method for producing antibodies in plant cells
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
AU728794B2
(en)
|
1996-03-05 |
2001-01-18 |
Scripps Research Institute, The |
Recombinant constructs encoding T cell receptors specific for human HLA-restricted tumor antigens
|
|
EP0826696B1
(de)
|
1996-09-03 |
2002-05-29 |
GSF-Forschungszentrum für Umwelt und Gesundheit GmbH |
Verwendung bi-und trispezifischer Antikörper zur Induktion einer Tumorimmunität
|
|
ATE549918T1
(de)
|
1996-12-03 |
2012-04-15 |
Amgen Fremont Inc |
Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden
|
|
JP2002512510A
(ja)
|
1997-03-06 |
2002-04-23 |
インフィジェン・インコーポレーテッド |
動物のクローニング方法
|
|
CN1203922A
(zh)
|
1997-03-21 |
1999-01-06 |
三共株式会社 |
人源化抗人fas抗体
|
|
TR199902553T2
(xx)
|
1997-04-14 |
2000-03-21 |
Micromet Gesellschaft F�R Biomedizinische Forschung Mbh |
�nsan v�cuduna kar�� antijen resept�rlerinin �retimi i�in yeni metod ve kullan�mlar�.
|
|
DK0979281T3
(da)
|
1997-05-02 |
2005-11-21 |
Genentech Inc |
Fremgangsmåde til fremstilling af multispecifikke antistoffer med heteromultimere og fælles bestanddele
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6774279B2
(en)
|
1997-05-30 |
2004-08-10 |
Carnegie Institution Of Washington |
Use of FLP recombinase in mice
|
|
CA2305712A1
(en)
|
1997-10-03 |
1999-04-15 |
Chugai Seiyaku Kabushiki Kaisha |
Natural humanized antibody
|
|
NZ503859A
(en)
|
1997-11-18 |
2003-02-28 |
Pioneer Hi Bred Int |
Non-identical minimal recombination sites (FRT) which are non-identical for targeted integration of nucleotide sequences into transformed plants
|
|
GB9823930D0
(en)
|
1998-11-03 |
1998-12-30 |
Babraham Inst |
Murine expression of human ig\ locus
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
RU10506U1
(ru)
|
1999-04-08 |
1999-08-16 |
Кривулин Виталий Николаевич |
Ручной культиватор
|
|
CN100457914C
(zh)
|
1999-04-15 |
2009-02-04 |
荷兰克鲁塞尔公司 |
用编码腺病毒e1蛋白的序列在人体细胞中生产重组蛋白
|
|
JP2003501016A
(ja)
|
1999-05-27 |
2003-01-14 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
Adamのポリヌクレオチドおよびポリペプチド
|
|
GB0001448D0
(en)
|
2000-01-21 |
2000-03-08 |
Novartis Ag |
Organic compounds
|
|
AU2001245358A1
(en)
|
2000-02-29 |
2001-09-12 |
Auburn University |
Production of antibodies in transgenic plastids
|
|
CN101498731A
(zh)
|
2000-05-18 |
2009-08-05 |
日本烟草产业株式会社 |
抗协同刺激信号转导分子ailim的人单克隆抗体及其药物用途
|
|
AU2001264946A1
(en)
|
2000-05-24 |
2001-12-03 |
Imclone Systems Incorporated |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
|
CN1455817A
(zh)
|
2000-07-21 |
2003-11-12 |
(由农业部部长代表的)美利坚合众国 |
用于在真核基因组中置换、转移和富积dna的方法
|
|
EP1311530A4
(en)
|
2000-08-03 |
2004-10-06 |
Wim-Van Schooten |
PRODUCTION OF HUMANIZED ANTIBODIES IN TRANSGENIC ANIMALS
|
|
EP1184458A1
(en)
|
2000-08-28 |
2002-03-06 |
U-BISys B.V. |
Differentially expressed CD46 epitopes, proteinaceous molecules capable of binding thereto, and uses thereof
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6586251B2
(en)
|
2000-10-31 |
2003-07-01 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US7105348B2
(en)
|
2000-10-31 |
2006-09-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
WO2002040685A2
(en)
|
2000-11-16 |
2002-05-23 |
Cornell Research Foundation, Inc. |
Vectors for conditional gene inactivation
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
DE10064750A1
(de)
|
2000-12-22 |
2002-06-27 |
Bayer Ag |
Verfahren zur Herstellung von 1,6-Hexandiolen
|
|
PA8535501A1
(es)
|
2001-01-05 |
2003-07-28 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
US6961875B2
(en)
|
2001-03-22 |
2005-11-01 |
International Business Machines Corporation |
Method and apparatus for capturing event traces for debug and analysis
|
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
|
US7034134B2
(en)
|
2001-04-26 |
2006-04-25 |
Bristol-Myers Squibb Company |
Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
|
|
US7074611B2
(en)
|
2001-04-27 |
2006-07-11 |
Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) |
Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof
|
|
EP1970448A1
(en)
|
2001-05-11 |
2008-09-17 |
Kirin Pharma Kabushiki Kaisha |
Human artificial chromosome containting human antibody lambda light chain and non-human animal containting the human artificial chromosome capable of genetic transmission
|
|
AU2002319402B2
(en)
|
2001-06-28 |
2008-09-11 |
Domantis Limited |
Dual-specific ligand and its use
|
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
|
WO2003062370A2
(en)
|
2001-07-19 |
2003-07-31 |
Perlan Therapeutics, Inc. |
Multimeric proteins and methods of making and using same
|
|
ATE476503T1
(de)
|
2001-10-01 |
2010-08-15 |
Deutsches Krebsforsch |
Verfahren zur herstellung von protein- bibliotheken und zur selektion von proteinen daraus
|
|
US20060199204A1
(en)
|
2001-10-05 |
2006-09-07 |
U.S. Epa |
Genetic testing for male factor infertility
|
|
US20030108925A1
(en)
|
2001-10-05 |
2003-06-12 |
U.S. Epa |
Genetic testing for male factor infertility
|
|
EP3698626A1
(en)
|
2001-11-30 |
2020-08-26 |
Amgen Fremont Inc. |
Transgenic animals bearing human ig lambda light chain genes
|
|
GB0130267D0
(en)
|
2001-12-19 |
2002-02-06 |
Neutec Pharma Plc |
Focussed antibody technology
|
|
AU2003214842A1
(en)
|
2002-01-17 |
2003-09-02 |
Albert Einstein College Of Medicine Of Yeshiva University |
Mutations caused by activation-induced cytidine deaminase
|
|
AU2003201093A1
(en)
|
2002-01-18 |
2003-07-30 |
Inovio As |
Bispecific antibody dna constructs for intramuscular administration
|
|
JP4518941B2
(ja)
|
2002-04-26 |
2010-08-04 |
中外製薬株式会社 |
アゴニスト抗体のスクリーニング方法
|
|
WO2003092611A2
(en)
|
2002-05-03 |
2003-11-13 |
Regeneron Pharmaceuticals, Inc. |
Methods of inducing formation of functional and organized lymphatic vessels
|
|
CN101824090B
(zh)
|
2002-06-14 |
2013-01-02 |
免疫医疗公司 |
人源化单克隆抗体hPAM4
|
|
CN101962408A
(zh)
|
2002-07-12 |
2011-02-02 |
杰斐逊·富特 |
超人源化抗体
|
|
EP2314629B2
(en)
|
2002-07-18 |
2022-11-16 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
|
CL2003002461A1
(es)
|
2002-11-27 |
2005-01-07 |
Dow Chemical Company Agroscien |
Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
|
|
GB0228210D0
(en)
|
2002-12-03 |
2003-01-08 |
Babraham Inst |
Single chain antibodies
|
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
GB0230201D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
|
EP1439234A1
(en)
|
2003-01-08 |
2004-07-21 |
ARTEMIS Pharmaceuticals GmbH |
Targeted transgenesis using the rosa26 locus
|
|
DE602004021095D1
(de)
|
2003-01-21 |
2009-06-25 |
Chugai Pharmaceutical Co Ltd |
Verfahren zum screening der leichten kette eines antikörpers
|
|
AU2004208031B2
(en)
|
2003-01-28 |
2009-10-08 |
Cellectis |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
|
|
CA2517519A1
(en)
|
2003-03-04 |
2004-09-16 |
Alexion Pharmaceuticals, Inc. |
Vectors used to create hybrid constant regions
|
|
WO2004106375A1
(en)
|
2003-05-30 |
2004-12-09 |
Merus Biopharmaceuticals B.V. I.O. |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
US7205148B2
(en)
|
2003-06-11 |
2007-04-17 |
Regeneron Pharmaceuticals, Inc. |
Genome mutation by intron insertion into an embryonic stem cell genome
|
|
CN103205436B
(zh)
|
2003-07-15 |
2016-05-25 |
人类多克隆治疗公司 |
人源化免疫球蛋白基因座
|
|
US20050153392A1
(en)
|
2003-08-11 |
2005-07-14 |
Roland Buelow |
Transgenesis with humanized immunoglobulin loci
|
|
RU2251699C1
(ru)
|
2003-09-25 |
2005-05-10 |
Киселев Всеволод Иванович |
Способ ранней и доклинической диагностики цервикального рака
|
|
WO2005038001A2
(en)
|
2003-10-14 |
2005-04-28 |
Therapeutic Human Polyclonals, Inc. |
Improved transgenesis by sperm-mediated gene transfer
|
|
WO2005070966A2
(en)
|
2004-01-16 |
2005-08-04 |
Regeneron Pharmaceuticals, Inc. |
Fusion polypeptides capable of activating receptors
|
|
JP4890269B2
(ja)
|
2004-02-12 |
2012-03-07 |
ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ |
Blimp1およびレポーター分子を共発現する改変細胞およびその使用方法
|
|
CN1560081A
(zh)
|
2004-02-17 |
2005-01-05 |
大连帝恩生物工程有限公司 |
用能产生人IgGl重链-κ轻链小鼠作为制备人源化单克隆抗体和应用
|
|
US7625549B2
(en)
|
2004-03-19 |
2009-12-01 |
Amgen Fremont Inc. |
Determining the risk of human anti-human antibodies in transgenic mice
|
|
WO2006044962A1
(en)
|
2004-10-19 |
2006-04-27 |
Regeneron Pharmaceuticals, Inc. |
Method for generating an animal homozygous for a genetic modification
|
|
CN101132811B
(zh)
*
|
2004-10-22 |
2012-05-30 |
米迪缪尼有限公司 |
抗hmgb1的高亲和力抗体及其用法
|
|
CN101084317A
(zh)
|
2004-10-22 |
2007-12-05 |
人类多克隆治疗公司 |
对内源免疫球蛋白表达的抑制
|
|
EP1815001B8
(en)
|
2004-11-26 |
2011-03-23 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Gene trap cassettes for random and targeted conditional gene inactivation
|
|
EP1662005A1
(en)
|
2004-11-26 |
2006-05-31 |
FrankGen Biotechnologie AG |
Enhancer-containing gene trap vectors for random and targeted gene trapping
|
|
US20110041370A1
(en)
|
2005-04-21 |
2011-02-24 |
Saint Andre M |
Face sheet, identification band, and related methods
|
|
JP2008538912A
(ja)
|
2005-04-29 |
2008-11-13 |
イナート・ファルマ |
遺伝子導入動物および組換え抗体の製造方法
|
|
EP1896578A4
(en)
|
2005-05-14 |
2008-11-05 |
Univ Fudan |
PIGGYBAC AS A TOOL FOR GENETIC HANDLING AND ANALYSIS IN VERTEBRATES
|
|
ES2564823T3
(es)
|
2005-05-27 |
2016-03-29 |
Ospedale San Raffaele S.R.L. |
Vector génico que comprende miARN
|
|
ATE416465T1
(de)
|
2005-06-30 |
2008-12-15 |
Borealis Tech Oy |
Überzug-schicht für energie- oder kommunikationskabel
|
|
FR2888850B1
(fr)
|
2005-07-22 |
2013-01-11 |
Pf Medicament |
Nouveaux anticorps anti-igf-ir et leurs applications
|
|
JP2009518320A
(ja)
|
2005-12-05 |
2009-05-07 |
シュムフォウエン アクティーゼルスカブ |
抗オルトポックスウイルス組換えポリクローナル抗体
|
|
SG169348A1
(en)
|
2006-01-25 |
2011-03-30 |
Univ Erasmus Medical Ct |
Generation of heavy-chain only antibodies in transgenic animals
|
|
GB2434578A
(en)
|
2006-01-26 |
2007-08-01 |
Univ Basel |
Transgenic animals
|
|
US7462759B2
(en)
|
2006-02-03 |
2008-12-09 |
Pioneer Hi-Bred International, Inc. |
Brittle stalk 2 gene family and related methods and uses
|
|
GB0615327D0
(en)
|
2006-03-30 |
2006-09-13 |
Univ Edinburgh |
Culture medium containing kinase inhibitors and uses thereof
|
|
JP5514539B2
(ja)
|
2006-03-31 |
2014-06-04 |
メダレックス・リミテッド・ライアビリティ・カンパニー |
ヒト抗体の調製に用いるためのキメラ抗体を発現するトランスジェニック動物
|
|
NZ587107A
(en)
|
2006-06-02 |
2012-05-25 |
Regeneron Pharma |
High affinity antibodies to human il-6 receptor
|
|
WO2007149246A2
(en)
|
2006-06-12 |
2007-12-27 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
WO2008022391A1
(en)
|
2006-08-22 |
2008-02-28 |
G2 Inflammation Pty Ltd |
Method for producing antibodies
|
|
ES2378407T3
(es)
|
2006-09-01 |
2012-04-12 |
Therapeutic Human Polyclonals, Inc. |
Aumento de la expresión de inmunoglobulina humana o humanizada en animales transgénicos no humanos
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
LT2769992T
(lt)
|
2006-10-02 |
2021-04-12 |
Regeneron Pharmaceuticals, Inc. |
Didelio afiniškumo žmogaus antikūnai, atpažįstantys žmogaus il-4 receptorių
|
|
RU2448979C2
(ru)
|
2006-12-14 |
2012-04-27 |
Ридженерон Фармасьютикалз, Инк. |
Антитела человека к дельта-подобному лиганду-4 человека
|
|
GB0700194D0
(en)
|
2007-01-05 |
2007-02-14 |
Univ Edinburgh |
Humanisation of animals
|
|
CN101688228B
(zh)
|
2007-03-13 |
2014-12-24 |
国家犾太健康中心 |
抗体产生的方法
|
|
US9043994B2
(en)
|
2007-03-13 |
2015-06-02 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
GB0706628D0
(en)
|
2007-04-04 |
2007-05-16 |
Univ Erasmus |
Germ-line manipulation 1
|
|
CA2688834C
(en)
|
2007-06-01 |
2020-01-07 |
Ronald Buelow |
Compositions and methods for inhibiting endogenous immunoglobulin genes and producing transgenic human idiotype antibodies
|
|
WO2009013620A2
(en)
|
2007-06-11 |
2009-01-29 |
Erasmus University Medical Center Rotterdam |
Homologous recombination
|
|
ITMI20071522A1
(it)
|
2007-07-27 |
2009-01-28 |
Areta Internat S R L |
Vaccino idiotipico
|
|
WO2009097006A2
(en)
|
2007-08-10 |
2009-08-06 |
Medarex, Inc. |
Hco32 and hco27 and related examples
|
|
MX2010001684A
(es)
|
2007-08-15 |
2010-04-21 |
Amunix Inc |
Composiciones y metodos para modificar propiedades de polipeptidos biologicamente activos.
|
|
CN101970491A
(zh)
|
2007-08-30 |
2011-02-09 |
沃尔特及伊莱萨霍尔医学研究院 |
树突状细胞标记物及其用途
|
|
EP3124497B1
(en)
|
2007-09-14 |
2020-04-15 |
Adimab, LLC |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
US8536310B2
(en)
|
2007-10-17 |
2013-09-17 |
Arca Biopharma, Inc. |
Antibodies to CLL-1
|
|
US7659842B2
(en)
|
2007-10-24 |
2010-02-09 |
Infineon Technologies Ag |
Quantization error reduction in PWM full-MASH converters
|
|
DK2222706T4
(en)
|
2007-12-14 |
2016-11-21 |
Novo Nordisk As |
Antibodies that bind to NKG2D and its use
|
|
EP3663318A1
(en)
|
2008-01-07 |
2020-06-10 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
|
TWI476280B
(zh)
|
2008-03-07 |
2015-03-11 |
Regeneron Pharma |
來自二倍體宿主胚胎注射之es-細胞衍生的老鼠
|
|
EP2271758B1
(en)
|
2008-04-14 |
2018-09-12 |
Innovative Targeting Solutions Inc. |
Sequence diversity generation in immunoglobulins
|
|
ES2436044T3
(es)
|
2008-05-23 |
2013-12-26 |
Ablexis, Llc |
Procedimiento de generación de anticuerpos de dominio VL individual en animales transgénicos
|
|
RU2731084C2
(ru)
|
2008-06-27 |
2020-08-28 |
Мерюс Н.В. |
Продуцирующие антитела млекопитающие, не являющиеся человеком
|
|
WO2010039900A2
(en)
|
2008-09-30 |
2010-04-08 |
Aliva Biopharmaceuticals, Inc. |
Non-human mammals for the production of chimeric antibodies
|
|
WO2010054007A1
(en)
|
2008-11-07 |
2010-05-14 |
Fabrus Llc |
Combinatorial antibody libraries and uses thereof
|
|
US8497325B2
(en)
|
2008-12-15 |
2013-07-30 |
Exxonmobil Chemical Patents Inc. |
Thermoplastic polyolefin blends and films therefrom
|
|
CA2747534C
(en)
|
2008-12-18 |
2020-08-18 |
Erasmus University Medical Center Rotterdam |
Non-human transgenic animals expressing humanised antibodies and use therof
|
|
US20110305692A1
(en)
|
2009-02-24 |
2011-12-15 |
Glaxo Group Limited |
Antigen-binding contructs
|
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
|
CN102427978B
(zh)
|
2009-05-07 |
2016-01-20 |
沃尔沃建筑设备公司 |
工程机械和用于操作工程机械的方法
|
|
WO2010136598A1
(en)
|
2009-05-29 |
2010-12-02 |
Morphosys Ag |
A collection and methods for its use
|
|
LT2975051T
(lt)
|
2009-06-26 |
2021-07-12 |
Regeneron Pharmaceuticals, Inc. |
Lengvai išskiriami bispecifiniai antikūnai su natyvios formos imunoglobulinu
|
|
CN102638971B
(zh)
|
2009-07-08 |
2015-10-07 |
科马布有限公司 |
动物模型及治疗分子
|
|
RU2425880C2
(ru)
*
|
2009-07-30 |
2011-08-10 |
Учреждение Российской академии наук Институт общей генетики им. Н.И. Вавилова РАН |
Способ получения трансгенных мышей
|
|
EP2502992A4
(en)
|
2009-11-17 |
2013-06-12 |
|
CHROMOSOME ARTIFICIAL HUMAN VECTOR
|
|
DK2509409T3
(en)
|
2009-12-10 |
2016-11-14 |
Regeneron Pharma |
MICE, WHICH PRODUCES HEAVY CHAIN ANTIBODIES
|
|
HRP20151188T4
(hr)
|
2010-02-08 |
2021-10-01 |
Regeneron Pharmaceuticals, Inc. |
Miš sa zajedničkim lakim lancem
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
US20120021409A1
(en)
|
2010-02-08 |
2012-01-26 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
US20130185821A1
(en)
|
2010-02-08 |
2013-07-18 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
EP2569337A1
(en)
|
2010-05-14 |
2013-03-20 |
Rinat Neuroscience Corp. |
Heterodimeric proteins and methods for producing and purifying them
|
|
CN103228130B
(zh)
|
2010-06-17 |
2016-03-16 |
科马布有限公司 |
动物模型及治疗分子
|
|
SI2480675T1
(sl)
|
2010-06-22 |
2016-08-31 |
Regeneron Pharmaceuticals, Inc. |
Miši, ki izražajo lahko verigo s spremenljivo regijo humanega lambda in konstantno mišjo regijo
|
|
KR102306967B1
(ko)
|
2010-08-02 |
2021-10-01 |
리제너론 파아마슈티컬스, 인크. |
Vl 도메인을 포함하는 결합 단백질을 생성하는 마우스
|
|
WO2012063048A1
(en)
|
2010-11-08 |
2012-05-18 |
Kymab Limited |
Cells & vertebrates for enhanced somatic hypermutation and class switch recombination
|
|
LT2738259T
(lt)
|
2011-02-25 |
2020-03-10 |
Regeneron Pharmaceuticals, Inc. |
Adam6 pelės
|
|
PT3865581T
(pt)
|
2011-08-05 |
2024-10-04 |
Regeneron Pharma |
Murganhos da cadeia leve universal humanizada
|
|
US20130044257A1
(en)
|
2011-08-18 |
2013-02-21 |
Lattice Energy Technology Corporation |
Mobile device with side-mounted camera module
|
|
EP3741862A1
(en)
|
2011-09-19 |
2020-11-25 |
Kymab Limited |
Animals, repertoires & methods for the production of human antibodies
|
|
AU2012311286B2
(en)
|
2011-09-19 |
2018-07-26 |
Kymab Limited |
Antibodies, variable domains and chains tailored for human use
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
WO2013045916A1
(en)
|
2011-09-26 |
2013-04-04 |
Kymab Limited |
Chimaeric surrogate light chains (slc) comprising human vpreb
|
|
KR20140082824A
(ko)
|
2011-10-17 |
2014-07-02 |
리제너론 파아마슈티컬스, 인크. |
제한된 면역글로불린 중쇄 마우스
|
|
GB2496375A
(en)
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
|
US9253965B2
(en)
|
2012-03-28 |
2016-02-09 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
PT3527070T
(pt)
|
2011-12-20 |
2025-12-19 |
Regeneron Pharma |
Murganhos de cadeia leve humanizada
|
|
NZ810648A
(en)
|
2012-02-01 |
2025-11-28 |
Regeneron Pharma |
Humanized rodents that express heavy chains containing vl domains
|
|
DK2838918T3
(da)
|
2012-04-20 |
2019-08-12 |
Merus Nv |
Fremgangsmåder og midler til fremstilling af heterodimere ig-lignende molekyler
|
|
EP3912464A1
(en)
|
2012-06-12 |
2021-11-24 |
Regeneron Pharmaceuticals, Inc. |
Humanized non-human animals with restricted immunoglobulin heavy chain loci
|
|
EP4218409B1
(en)
|
2013-03-13 |
2025-02-12 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
JP2016519568A
(ja)
|
2013-03-13 |
2016-07-07 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
共通軽鎖のマウス
|