|
GB8626413D0
(en)
|
1986-11-05 |
1986-12-03 |
Gilliland L K |
Antibodies
|
|
GB8626412D0
(en)
|
1986-11-05 |
1986-12-03 |
Clark M R |
Antibodies
|
|
ATE190355T1
(de)
|
1988-09-06 |
2000-03-15 |
Xoma Corp |
Genexpressions-elemente und herstellung von chimären maus-mensch-antikörpern
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
WO1991000906A1
(en)
|
1989-07-12 |
1991-01-24 |
Genetics Institute, Inc. |
Chimeric and transgenic animals capable of producing human antibodies
|
|
US5574205A
(en)
|
1989-07-25 |
1996-11-12 |
Cell Genesys |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
AU656720B2
(en)
|
1989-12-01 |
1995-02-16 |
Gene Pharming Europe Bv |
Production of recombinant polypeptides by bovine species and transgenic methods
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6657103B1
(en)
|
1990-01-12 |
2003-12-02 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
US7041871B1
(en)
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US7067284B1
(en)
|
1992-01-27 |
2006-06-27 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
WO1994002602A1
(en)
|
1992-07-24 |
1994-02-03 |
Cell Genesys, Inc. |
Generation of xenogeneic antibodies
|
|
ATE149570T1
(de)
|
1992-08-17 |
1997-03-15 |
Genentech Inc |
Bispezifische immunoadhesine
|
|
JPH08503617A
(ja)
|
1992-12-01 |
1996-04-23 |
プロテイン デザイン ラブズ、インコーポレーテッド |
L−セレクチンに反応性のヒト化抗体
|
|
GB9308271D0
(en)
|
1993-04-21 |
1993-06-02 |
Univ Edinburgh |
Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
|
|
US5877396A
(en)
|
1993-04-23 |
1999-03-02 |
Sloan Kettering Institute For Cancer Research |
Mice mutant for functional Fc receptors and method of treating autoimmune diseases
|
|
AU6819494A
(en)
|
1993-04-26 |
1994-11-21 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5693506A
(en)
|
1993-11-16 |
1997-12-02 |
The Regents Of The University Of California |
Process for protein production in plants
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
EP0739412B1
(en)
|
1993-12-23 |
2002-02-27 |
Infigen, Inc. |
ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS
|
|
GB9401380D0
(en)
|
1994-01-25 |
1994-03-23 |
Pharmaceutical Proteins Ltd |
Embryonic cell isolation
|
|
DK1231268T3
(da)
|
1994-01-31 |
2005-11-21 |
Univ Boston |
Polyklonale antistofbiblioteker
|
|
US7119248B1
(en)
|
1994-04-12 |
2006-10-10 |
Miltenyi Biotec Gmbh |
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
|
|
US6080560A
(en)
|
1994-07-25 |
2000-06-27 |
Monsanto Company |
Method for producing antibodies in plant cells
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
WO1997032603A1
(en)
|
1996-03-05 |
1997-09-12 |
The Scripps Research Institute |
Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens
|
|
ES2176574T3
(es)
|
1996-09-03 |
2002-12-01 |
Gsf Forschungszentrum Umwelt |
Utilizacion de anticuerpos bi y triespecificos para la induccion de inmunidad tumoral.
|
|
DE69738539T2
(de)
|
1996-12-03 |
2009-03-26 |
Amgen Fremont Inc. |
Vollkommen humane Antikörper die EGFR binden
|
|
NZ337495A
(en)
|
1997-03-06 |
2001-06-29 |
Infigen Inc |
Bovine primordial germ cells and their use in cloning
|
|
CN1203922A
(zh)
|
1997-03-21 |
1999-01-06 |
三共株式会社 |
人源化抗人fas抗体
|
|
BRPI9809391B8
(pt)
|
1997-04-14 |
2021-05-25 |
Amgen Res Munich Gmbh |
processo para a produção de um receptor de antígeno anti-humano, anticorpo humano e composição farmacêutica
|
|
EP0979281B1
(en)
|
1997-05-02 |
2005-07-20 |
Genentech, Inc. |
A method for making multispecific antibodies having heteromultimeric and common components
|
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
US6774279B2
(en)
|
1997-05-30 |
2004-08-10 |
Carnegie Institution Of Washington |
Use of FLP recombinase in mice
|
|
JP3992298B2
(ja)
|
1997-10-03 |
2007-10-17 |
中外製薬株式会社 |
天然ヒト型化抗体
|
|
ATE401410T1
(de)
|
1997-11-18 |
2008-08-15 |
Pioneer Hi Bred Int |
Zusammensetzungen und verfahren für die genetische modifizierung von pflanzen
|
|
GB9823930D0
(en)
|
1998-11-03 |
1998-12-30 |
Babraham Inst |
Murine expression of human ig\ locus
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
RU10506U1
(ru)
|
1999-04-08 |
1999-08-16 |
Кривулин Виталий Николаевич |
Ручной культиватор
|
|
ATE289354T1
(de)
|
1999-04-15 |
2005-03-15 |
Crucell Holland Bv |
Verwendung von adenovirus e1 protein sequenzen kodierenden, zur herstellung von rekombinanten proteinen in menschlichen zellen.
|
|
JP2003501016A
(ja)
|
1999-05-27 |
2003-01-14 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
Adamのポリヌクレオチドおよびポリペプチド
|
|
GB0001448D0
(en)
|
2000-01-21 |
2000-03-08 |
Novartis Ag |
Organic compounds
|
|
CA2401965A1
(en)
|
2000-02-29 |
2001-09-07 |
Auburn University |
Production of antibodies in transgenic plastids
|
|
CN101498731A
(zh)
|
2000-05-18 |
2009-08-05 |
日本烟草产业株式会社 |
抗协同刺激信号转导分子ailim的人单克隆抗体及其药物用途
|
|
WO2001090192A2
(en)
|
2000-05-24 |
2001-11-29 |
Imclone Systems Incorporated |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
|
AU2001277076A1
(en)
|
2000-07-21 |
2002-02-05 |
The United States Of America As Represented By The Secretary Of Agriculture |
Methods for the replacement, translocation and stacking of DNA in eukaryotic genomes
|
|
CA2634294A1
(en)
|
2000-08-03 |
2002-02-14 |
Therapeutic Human Polyclonals, Inc. |
Production of humanized antibodies in transgenic animals
|
|
EP1184458A1
(en)
|
2000-08-28 |
2002-03-06 |
U-BISys B.V. |
Differentially expressed CD46 epitopes, proteinaceous molecules capable of binding thereto, and uses thereof
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US7105348B2
(en)
|
2000-10-31 |
2006-09-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6586251B2
(en)
|
2000-10-31 |
2003-07-01 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6596541B2
(en)
*
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
AU2002219841A1
(en)
|
2000-11-16 |
2002-05-27 |
Cornell Research Foundation Inc. |
Vectors for conditional gene inactivation
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
DE10064750A1
(de)
|
2000-12-22 |
2002-06-27 |
Bayer Ag |
Verfahren zur Herstellung von 1,6-Hexandiolen
|
|
AR032028A1
(es)
|
2001-01-05 |
2003-10-22 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
US6961875B2
(en)
|
2001-03-22 |
2005-11-01 |
International Business Machines Corporation |
Method and apparatus for capturing event traces for debug and analysis
|
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
|
US7034134B2
(en)
|
2001-04-26 |
2006-04-25 |
Bristol-Myers Squibb Company |
Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
|
|
US7074611B2
(en)
|
2001-04-27 |
2006-07-11 |
Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) |
Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof
|
|
DE60227067D1
(de)
|
2001-05-11 |
2008-07-24 |
Kirin Pharma Kk |
Künstliches menschliches chromosom mit dem gen für die lambda-leichte kette menschlicher antikörper
|
|
DE60237282D1
(de)
|
2001-06-28 |
2010-09-23 |
Domantis Ltd |
Doppelspezifischer ligand und dessen verwendung
|
|
WO2004006955A1
(en)
|
2001-07-12 |
2004-01-22 |
Jefferson Foote |
Super humanized antibodies
|
|
WO2003062370A2
(en)
|
2001-07-19 |
2003-07-31 |
Perlan Therapeutics, Inc. |
Multimeric proteins and methods of making and using same
|
|
DE50115587D1
(de)
|
2001-10-01 |
2010-09-16 |
Deutsches Krebsforsch |
Verfahren zur Herstellung von Protein-Bibliotheken und zur Selektion von Proteinen daraus
|
|
US20060199204A1
(en)
|
2001-10-05 |
2006-09-07 |
U.S. Epa |
Genetic testing for male factor infertility
|
|
WO2003031656A1
(en)
|
2001-10-05 |
2003-04-17 |
United States Environmental Protection Agency |
Genetic testing for male factor infertility
|
|
US7435871B2
(en)
|
2001-11-30 |
2008-10-14 |
Amgen Fremont Inc. |
Transgenic animals bearing human Igλ light chain genes
|
|
GB0130267D0
(en)
|
2001-12-19 |
2002-02-06 |
Neutec Pharma Plc |
Focussed antibody technology
|
|
AU2003214842A1
(en)
|
2002-01-17 |
2003-09-02 |
Albert Einstein College Of Medicine Of Yeshiva University |
Mutations caused by activation-induced cytidine deaminase
|
|
US20040052773A1
(en)
|
2002-01-18 |
2004-03-18 |
Inovio As |
Production of multi-chain protein from muscle
|
|
EP1505148B1
(en)
|
2002-04-26 |
2009-04-15 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of screening for agonistic antibodies
|
|
WO2003092611A2
(en)
|
2002-05-03 |
2003-11-13 |
Regeneron Pharmaceuticals, Inc. |
Methods of inducing formation of functional and organized lymphatic vessels
|
|
EP1519958B1
(en)
|
2002-06-14 |
2014-10-15 |
Immunomedics, Inc. |
Humanized monoclonal antibody hpam4
|
|
CN101962408A
(zh)
|
2002-07-12 |
2011-02-02 |
杰斐逊·富特 |
超人源化抗体
|
|
SI1523496T1
(sl)
|
2002-07-18 |
2011-11-30 |
Merus B V |
Rekombinantno proizvajanje zmesi protiteles
|
|
CL2003002461A1
(es)
|
2002-11-27 |
2005-01-07 |
Dow Chemical Company Agroscien |
Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
|
|
GB0228210D0
(en)
|
2002-12-03 |
2003-01-08 |
Babraham Inst |
Single chain antibodies
|
|
GB0230201D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
EP1439234A1
(en)
|
2003-01-08 |
2004-07-21 |
ARTEMIS Pharmaceuticals GmbH |
Targeted transgenesis using the rosa26 locus
|
|
WO2004065611A1
(ja)
|
2003-01-21 |
2004-08-05 |
Chugai Seiyaku Kabushiki Kaisha |
抗体の軽鎖スクリーニング方法
|
|
EP1590468A2
(en)
|
2003-01-28 |
2005-11-02 |
Cellectis |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
|
|
CA2517519A1
(en)
|
2003-03-04 |
2004-09-16 |
Alexion Pharmaceuticals, Inc. |
Vectors used to create hybrid constant regions
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
EP2395017A3
(en)
|
2003-05-30 |
2012-12-19 |
Merus B.V. |
Design and use of paired variable regions of specific binding molecules
|
|
US7205148B2
(en)
|
2003-06-11 |
2007-04-17 |
Regeneron Pharmaceuticals, Inc. |
Genome mutation by intron insertion into an embryonic stem cell genome
|
|
MXPA06000562A
(es)
|
2003-07-15 |
2006-03-30 |
Therapeutic Human Polyclonals |
Loci de inmunoglobulina humanizada.
|
|
US20050153392A1
(en)
|
2003-08-11 |
2005-07-14 |
Roland Buelow |
Transgenesis with humanized immunoglobulin loci
|
|
RU2251699C1
(ru)
|
2003-09-25 |
2005-05-10 |
Киселев Всеволод Иванович |
Способ ранней и доклинической диагностики цервикального рака
|
|
WO2005038001A2
(en)
|
2003-10-14 |
2005-04-28 |
Therapeutic Human Polyclonals, Inc. |
Improved transgenesis by sperm-mediated gene transfer
|
|
DK1709081T3
(da)
|
2004-01-16 |
2011-06-06 |
Regeneron Pharma |
Fusionspolypeptider, der kan aktivere receptorer
|
|
EP1723235B1
(en)
|
2004-02-12 |
2012-06-27 |
The Walter And Eliza Hall Institute Of Medical Research |
Modified cells that co-express blimp1 and a reporter molecule and methods of using the same
|
|
CN1560081A
(zh)
|
2004-02-17 |
2005-01-05 |
大连帝恩生物工程有限公司 |
用能产生人IgGl重链-κ轻链小鼠作为制备人源化单克隆抗体和应用
|
|
US7625549B2
(en)
|
2004-03-19 |
2009-12-01 |
Amgen Fremont Inc. |
Determining the risk of human anti-human antibodies in transgenic mice
|
|
EP1802193B1
(en)
|
2004-10-19 |
2014-04-30 |
Regeneron Pharmaceuticals, Inc. |
Method for generating a mouse homozygous for a genetic modification
|
|
WO2007001422A2
(en)
*
|
2004-10-22 |
2007-01-04 |
Medimmune, Inc. |
High affinity antibodies against hmgb1 and methods of use thereof
|
|
JP2008517600A
(ja)
|
2004-10-22 |
2008-05-29 |
セラピューティック ヒューマン ポリクローナルズ, インコーポレイテッド |
ヒト以外のトランスジェニック動物における内因性免疫グロブリン発現の抑制
|
|
EP1662005A1
(en)
|
2004-11-26 |
2006-05-31 |
FrankGen Biotechnologie AG |
Enhancer-containing gene trap vectors for random and targeted gene trapping
|
|
DK1815001T3
(da)
|
2004-11-26 |
2011-05-16 |
Helmholtz Zentrum Muenchen |
Genfældekassetter til tilfældig og målrettet konditioneret geninaktivering
|
|
US20110041370A1
(en)
|
2005-04-21 |
2011-02-24 |
Saint Andre M |
Face sheet, identification band, and related methods
|
|
WO2006117699A2
(en)
|
2005-04-29 |
2006-11-09 |
Innate Pharma |
Transgenic animals and methods of making recombinant antibodies
|
|
US20100154070A1
(en)
|
2005-05-14 |
2010-06-17 |
Tian Xu |
PiggyBac as a Tool for Genetic Manipulation and Analysis in Vertebrates
|
|
PL2002003T3
(pl)
|
2005-05-27 |
2016-06-30 |
Ospedale San Raffaele Srl |
Wektor genetyczny zawierający mi-RNA
|
|
EP1739691B1
(en)
|
2005-06-30 |
2008-12-03 |
Borealis Technology Oy |
Outer sheath layer for power or communication cable
|
|
FR2888850B1
(fr)
|
2005-07-22 |
2013-01-11 |
Pf Medicament |
Nouveaux anticorps anti-igf-ir et leurs applications
|
|
JP2009518320A
(ja)
|
2005-12-05 |
2009-05-07 |
シュムフォウエン アクティーゼルスカブ |
抗オルトポックスウイルス組換えポリクローナル抗体
|
|
BRPI0706750A2
(pt)
|
2006-01-25 |
2011-04-05 |
Univ Erasmus Medical Ct |
geração de anticorpos de cadeia pesada em animais transgênicos
|
|
GB2434578A
(en)
|
2006-01-26 |
2007-08-01 |
Univ Basel |
Transgenic animals
|
|
US7462759B2
(en)
|
2006-02-03 |
2008-12-09 |
Pioneer Hi-Bred International, Inc. |
Brittle stalk 2 gene family and related methods and uses
|
|
GB0615327D0
(en)
|
2006-03-30 |
2006-09-13 |
Univ Edinburgh |
Culture medium containing kinase inhibitors and uses thereof
|
|
EP2505058A1
(en)
|
2006-03-31 |
2012-10-03 |
Medarex, Inc. |
Transgenic animals expressing chimeric antibodies for use in preparing human antibodies
|
|
CA2652976C
(en)
|
2006-06-02 |
2015-08-11 |
Regeneron Pharmaceuticals, Inc. |
High affinity antibodies to human il-6 receptor
|
|
US20090217397A1
(en)
|
2006-06-12 |
2009-08-27 |
Patrick Stern |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
JP2010501165A
(ja)
|
2006-08-22 |
2010-01-21 |
ジーツー インフラメイション プロプライエタリー リミテッド |
抗体の作製方法
|
|
WO2008027986A2
(en)
|
2006-09-01 |
2008-03-06 |
Therapeutic Human Polyclonals, Inc. |
Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
WO2008054606A2
(en)
|
2006-10-02 |
2008-05-08 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human il-4 receptor
|
|
NO347649B1
(no)
|
2006-12-14 |
2024-02-12 |
Regeneron Pharma |
Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse.
|
|
GB0700194D0
(en)
|
2007-01-05 |
2007-02-14 |
Univ Edinburgh |
Humanisation of animals
|
|
WO2008112226A2
(en)
|
2007-03-13 |
2008-09-18 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
JP2010521170A
(ja)
|
2007-03-13 |
2010-06-24 |
ナショナル ジューイッシュ ヘルス |
抗体の生成方法
|
|
GB0706628D0
(en)
|
2007-04-04 |
2007-05-16 |
Univ Erasmus |
Germ-line manipulation 1
|
|
EP2602323B1
(en)
|
2007-06-01 |
2018-02-28 |
Open Monoclonal Technology, Inc. |
Compositions and methods for inhibiting endogenous immunoglobin genes and producing transgenic human idiotype antibodies
|
|
WO2009013620A2
(en)
|
2007-06-11 |
2009-01-29 |
Erasmus University Medical Center Rotterdam |
Homologous recombination
|
|
ITMI20071522A1
(it)
|
2007-07-27 |
2009-01-28 |
Areta Internat S R L |
Vaccino idiotipico
|
|
US9693539B2
(en)
|
2007-08-10 |
2017-07-04 |
E. R. Squibb & Sons, L.L.C. |
HCO32 and HCO27 and related examples
|
|
BRPI0815416A2
(pt)
|
2007-08-15 |
2014-10-21 |
Amunix Inc |
Composições e métodos para modificar propriedades de polipeptídeos biologicamente ativos
|
|
BRPI0815848A2
(pt)
|
2007-08-30 |
2017-06-06 |
The Burnet Inst |
composto, linhagem de célula que produz anticorpo estável, composição, métodos para modular uma resposta imune em um indivíduo e para tratar e/ou prevenir uma doença, usos de um composto e/ou uma composição e de células dendríticas ou precursores das mesmas, métodos para enriquecer e detectar células dendríticas ou um subconjunto ou precursores das mesmas, polipeptídeo, polinucleotídeo vetor, célula hospedeira, planta transgênica, animal não humano transgênico, extrato, processo para preparar um composto ou um polipeptídeo, população enriquecida de células dendríticas e/ou precursores das mesmas, população de célula dendrítica expandida e/ou precursores das mesmas, métodos para identificar uma molécula que se liga a um polipeptídeo e para triar quanto a um composto que se liga a um polipeptídeo, uso de um polipeptídeo, um polinucleotídeo, um vetor, uma célula hospedeira, uma planta transgênica, um extrato, uma população de célula e/ou uma composição, método para produzir um composto, e, kit.
|
|
CA2697193C
(en)
|
2007-09-14 |
2017-06-06 |
Adimab, Inc. |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
US8536310B2
(en)
|
2007-10-17 |
2013-09-17 |
Arca Biopharma, Inc. |
Antibodies to CLL-1
|
|
US7659842B2
(en)
|
2007-10-24 |
2010-02-09 |
Infineon Technologies Ag |
Quantization error reduction in PWM full-MASH converters
|
|
KR101615935B1
(ko)
|
2007-12-14 |
2016-04-28 |
노보 노르디스크 에이/에스 |
인간 nkg2d에 대한 항체 및 그것의 용도
|
|
PT2235064E
(pt)
|
2008-01-07 |
2016-03-01 |
Amgen Inc |
Método de preparação de moléculas heterodiméricas de fc de anticorpos utilizando efeitos de indução eletrostática
|
|
TWI476280B
(zh)
|
2008-03-07 |
2015-03-11 |
Regeneron Pharma |
來自二倍體宿主胚胎注射之es-細胞衍生的老鼠
|
|
EP2271758B1
(en)
|
2008-04-14 |
2018-09-12 |
Innovative Targeting Solutions Inc. |
Sequence diversity generation in immunoglobulins
|
|
EP2669298A3
(en)
|
2008-05-23 |
2014-02-26 |
Ablexis, LLC |
Single variable immunoglobulin domain comprising VL-DH-JL
|
|
RU2559524C2
(ru)
|
2008-06-27 |
2015-08-10 |
Мерюс Б.В. |
Продуцирующие антитела млекопитающие, не являющиеся человеком
|
|
LT2346994T
(lt)
|
2008-09-30 |
2022-03-10 |
Ablexis, Llc |
Knock-in pelė, skirta chimerinių antikūnų gamybai
|
|
EP2356270B1
(en)
|
2008-11-07 |
2016-08-24 |
Fabrus Llc |
Combinatorial antibody libraries and uses thereof
|
|
US8497325B2
(en)
|
2008-12-15 |
2013-07-30 |
Exxonmobil Chemical Patents Inc. |
Thermoplastic polyolefin blends and films therefrom
|
|
CN112690250B
(zh)
|
2008-12-18 |
2024-03-08 |
伊拉兹马斯大学鹿特丹医学中心 |
表达人源化抗体的非人转基因动物及其用途
|
|
EP2401298A1
(en)
|
2009-02-24 |
2012-01-04 |
Glaxo Group Limited |
Antigen-binding constructs
|
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
|
RU2011149353A
(ru)
|
2009-05-07 |
2013-06-20 |
Вольво Констракшн Эквипмент Аб |
Рабочая машина и способ управления ее работой
|
|
NZ596603A
(en)
|
2009-05-29 |
2013-07-26 |
Morphosys Ag |
A collection of antibodies or fragments having properties relevant to developability
|
|
MX368932B
(es)
|
2009-06-26 |
2019-10-22 |
Regeneron Pharma |
Anticuerpos biespecificos facilmente aislados con formato de inmunoglobulina original.
|
|
EP3028565B1
(en)
|
2009-07-08 |
2017-09-27 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
RU2425880C2
(ru)
*
|
2009-07-30 |
2011-08-10 |
Учреждение Российской академии наук Институт общей генетики им. Н.И. Вавилова РАН |
Способ получения трансгенных мышей
|
|
AU2010320130B2
(en)
|
2009-11-17 |
2015-03-12 |
Sab, Llc |
Human artificial chromosome vector
|
|
US8754287B2
(en)
|
2009-12-10 |
2014-06-17 |
Regeneron Pharmaceuticals, Inc. |
Mice that make heavy chain antibodies
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
US20120021409A1
(en)
|
2010-02-08 |
2012-01-26 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
US20130185821A1
(en)
|
2010-02-08 |
2013-07-18 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
SMT201900372T1
(it)
|
2010-02-08 |
2019-09-09 |
Regeneron Pharma |
Topo con catena leggera comune
|
|
EP2569337A1
(en)
|
2010-05-14 |
2013-03-20 |
Rinat Neuroscience Corp. |
Heterodimeric proteins and methods for producing and purifying them
|
|
NZ605966A
(en)
|
2010-06-17 |
2015-04-24 |
Kymab Ltd |
Animal models and therapeutic molecules
|
|
SI2480676T1
(sl)
|
2010-06-22 |
2016-10-28 |
Regeneron Pharmaceuticals, Inc. |
Hibridna mišja lahka veriga
|
|
RU2612903C2
(ru)
|
2010-08-02 |
2017-03-13 |
Ридженерон Фармасьютикалз, Инк. |
Мыши, у которых вырабатываются связывающие белки, содержащие vl-домены
|
|
WO2012063048A1
(en)
|
2010-11-08 |
2012-05-18 |
Kymab Limited |
Cells & vertebrates for enhanced somatic hypermutation and class switch recombination
|
|
DK2813573T1
(da)
|
2011-02-25 |
2015-01-12 |
Regeneron Pharma |
ADAM6 mus
|
|
HUE068728T2
(hu)
|
2011-08-05 |
2025-01-28 |
Regeneron Pharma |
Humanizált univerzális könnyûláncú egerek
|
|
US20130044257A1
(en)
|
2011-08-18 |
2013-02-21 |
Lattice Energy Technology Corporation |
Mobile device with side-mounted camera module
|
|
EP2757875B2
(en)
|
2011-09-19 |
2023-03-22 |
Kymab Limited |
Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
|
|
JP2014531452A
(ja)
|
2011-09-19 |
2014-11-27 |
カイマブ・リミテッド |
動物、レパートリーおよび方法
|
|
WO2013045916A1
(en)
|
2011-09-26 |
2013-04-04 |
Kymab Limited |
Chimaeric surrogate light chains (slc) comprising human vpreb
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
PL3216871T3
(pl)
|
2011-10-17 |
2022-03-21 |
Regeneron Pharmaceuticals, Inc. |
Ograniczony łańcuch ciężki immonoglobuliny pochodzącej od myszy
|
|
GB2496375A
(en)
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
|
US9253965B2
(en)
|
2012-03-28 |
2016-02-09 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
MX378871B
(es)
|
2011-12-20 |
2025-03-10 |
Regeneron Pharma |
Ratones con cadena ligera humanizada.
|
|
PL2809150T3
(pl)
|
2012-02-01 |
2020-04-30 |
Regeneron Pharmaceuticals, Inc. |
Humanizowane myszy wykazujące ekspresję łańcuchów ciężkich zawierających domeny VL
|
|
ES2743399T3
(es)
|
2012-04-20 |
2020-02-19 |
Merus Nv |
Métodos y medios para la producción de moléculas heterodiméricas similares a Ig
|
|
EP2858487B1
(en)
|
2012-06-12 |
2019-10-23 |
Regeneron Pharmaceuticals, Inc. |
Humanized non-human animals with restricted immunoglobulin heavy chain loci
|
|
PT3501272T
(pt)
|
2013-03-13 |
2023-03-29 |
Regeneron Pharma |
Murganhos que expressam um repertório limitado de cadeia leve de imunoglobulina
|
|
RU2015143108A
(ru)
|
2013-03-13 |
2017-04-20 |
Регенерон Фарматютикалз, Инк. |
Мышь с общей легкой цепью
|