|
GB8626412D0
(en)
|
1986-11-05 |
1986-12-03 |
Clark M R |
Antibodies
|
|
GB8626413D0
(en)
|
1986-11-05 |
1986-12-03 |
Gilliland L K |
Antibodies
|
|
DE68929167T2
(de)
|
1988-09-06 |
2000-11-16 |
Xoma Corp., Berkeley |
Genexpressions-Elemente und Herstellung von chimären Maus-Mensch-Antikörpern
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
WO1991000906A1
(en)
|
1989-07-12 |
1991-01-24 |
Genetics Institute, Inc. |
Chimeric and transgenic animals capable of producing human antibodies
|
|
US5574205A
(en)
|
1989-07-25 |
1996-11-12 |
Cell Genesys |
Homologous recombination for universal donor cells and chimeric mammalian hosts
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
ATE140027T1
(de)
|
1989-12-01 |
1996-07-15 |
Pharming Bv |
Herstellung rekombinanter polypeptide durch rinder und transgene methoden
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
DK0710719T3
(da)
|
1990-01-12 |
2007-07-09 |
Amgen Fremont Inc |
Frembringelse af xenogene antistoffer
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6657103B1
(en)
|
1990-01-12 |
2003-12-02 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US7041871B1
(en)
|
1995-10-10 |
2006-05-09 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
|
US7084260B1
(en)
|
1996-10-10 |
2006-08-01 |
Genpharm International, Inc. |
High affinity human antibodies and human antibodies against human antigens
|
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
US7067284B1
(en)
|
1992-01-27 |
2006-06-27 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
NZ255101A
(en)
|
1992-07-24 |
1997-08-22 |
Cell Genesys Inc |
A yeast artificial chromosome (yac) vector containing an hprt minigene expressible in murine stem cells and genetically modified rodent therefor
|
|
JPH08500017A
(ja)
|
1992-08-17 |
1996-01-09 |
ジェネンテク，インコーポレイテッド |
二特異的免疫アドヘジン
|
|
JPH08503617A
(ja)
|
1992-12-01 |
1996-04-23 |
プロテイン デザイン ラブズ、インコーポレーテッド |
Ｌ−セレクチンに反応性のヒト化抗体
|
|
GB9308271D0
(en)
|
1993-04-21 |
1993-06-02 |
Univ Edinburgh |
Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
|
|
US5877396A
(en)
|
1993-04-23 |
1999-03-02 |
Sloan Kettering Institute For Cancer Research |
Mice mutant for functional Fc receptors and method of treating autoimmune diseases
|
|
AU6819494A
(en)
|
1993-04-26 |
1994-11-21 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5693506A
(en)
|
1993-11-16 |
1997-12-02 |
The Regents Of The University Of California |
Process for protein production in plants
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
DE69430014D1
(de)
|
1993-12-23 |
2002-04-04 |
Infigen Inc |
EMBRYONALE STAMMZELLEN von Huftieren ALS KERNDONATOREN UND KERNTRANSFERTECHNIKEN ZUR HERSTELLUNG CHIMÄRER UND TRANSGENER TIERE
|
|
GB9401380D0
(en)
|
1994-01-25 |
1994-03-23 |
Pharmaceutical Proteins Ltd |
Embryonic cell isolation
|
|
PT744958E
(pt)
|
1994-01-31 |
2003-11-28 |
Univ Boston |
Bancos de anticorpos policlonais
|
|
US7119248B1
(en)
|
1994-04-12 |
2006-10-10 |
Miltenyi Biotec Gmbh |
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof
|
|
US6080560A
(en)
|
1994-07-25 |
2000-06-27 |
Monsanto Company |
Method for producing antibodies in plant cells
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
CA2246333A1
(en)
|
1996-03-05 |
1997-09-12 |
The Scripps Research Institute |
Recombinant constructs encoding t cell receptors specific for human hla-restricted tumor antigens
|
|
EP0826696B1
(de)
|
1996-09-03 |
2002-05-29 |
GSF-Forschungszentrum für Umwelt und Gesundheit GmbH |
Verwendung bi-und trispezifischer Antikörper zur Induktion einer Tumorimmunität
|
|
ATE549918T1
(de)
|
1996-12-03 |
2012-04-15 |
Amgen Fremont Inc |
Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden
|
|
EP0973871A1
(en)
|
1997-03-06 |
2000-01-26 |
Infigen, Inc. |
Method of cloning animals
|
|
CN1203922A
(zh)
|
1997-03-21 |
1999-01-06 |
三共株式会社 |
人源化抗人fas抗体
|
|
EP0970126B1
(en)
|
1997-04-14 |
2001-04-18 |
Micromet AG |
Novel method for the production of antihuman antigen receptors and uses thereof
|
|
US20020062010A1
(en)
*
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
|
JP4213224B2
(ja)
|
1997-05-02 |
2009-01-21 |
ジェネンテック，インコーポレーテッド |
ヘテロマルチマー及び共通成分を有する多重特異性抗体の製造方法
|
|
US6774279B2
(en)
|
1997-05-30 |
2004-08-10 |
Carnegie Institution Of Washington |
Use of FLP recombinase in mice
|
|
BR9812846A
(pt)
|
1997-10-03 |
2000-08-08 |
Chugai Pharmaceutical Co Ltd |
Anticorpo humanizado natural
|
|
US6331661B1
(en)
|
1997-11-18 |
2001-12-18 |
Pioneer Hi-Bred International, Inc. |
Method for directional stable transformation of eukaryotic cells
|
|
GB9823930D0
(en)
|
1998-11-03 |
1998-12-30 |
Babraham Inst |
Murine expression of human ig\ locus
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
RU10506U1
(ru)
|
1999-04-08 |
1999-08-16 |
Кривулин Виталий Николаевич |
Ручной культиватор
|
|
NZ514951A
(en)
|
1999-04-15 |
2004-02-27 |
Crucell Holland B |
Recombinant protein production in a cultured human cell
|
|
AU5043200A
(en)
|
1999-05-27 |
2000-12-18 |
Human Genome Sciences, Inc. |
Adam polynucleotides and polypeptides
|
|
GB0001448D0
(en)
|
2000-01-21 |
2000-03-08 |
Novartis Ag |
Organic compounds
|
|
EP1268832A4
(en)
|
2000-02-29 |
2003-04-02 |
Univ Auburn |
PRODUCTION OF ANTIBODIES IN TRANSGENIC PLASTIDES
|
|
RU2262511C2
(ru)
|
2000-05-18 |
2005-10-20 |
Джапан Тобакко, Инк. |
Человеческое моноклональное антитело против ailim, костимулирующей молекулы передачи сигнала, и его фармацевтическое применение
|
|
AU2001264946A1
(en)
|
2000-05-24 |
2001-12-03 |
Imclone Systems Incorporated |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
|
BR0112633A
(pt)
|
2000-07-21 |
2003-09-16 |
Us Agriculture |
Método para substituir, translocar e empilhar dna em genomas eucarióticos
|
|
WO2002012437A2
(en)
|
2000-08-03 |
2002-02-14 |
Schooten Wim Van |
Production of humanized antibodies in transgenic animals
|
|
EP1184458A1
(en)
|
2000-08-28 |
2002-03-06 |
U-BISys B.V. |
Differentially expressed CD46 epitopes, proteinaceous molecules capable of binding thereto, and uses thereof
|
|
US20020119148A1
(en)
|
2000-09-01 |
2002-08-29 |
Gerritsen Mary E. |
ErbB4 antagonists
|
|
US7105348B2
(en)
|
2000-10-31 |
2006-09-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US6586251B2
(en)
*
|
2000-10-31 |
2003-07-01 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US7449179B2
(en)
|
2000-11-16 |
2008-11-11 |
Cornell Research Foundation, Inc. |
Vectors for conditional gene inactivation
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
DE10064750A1
(de)
|
2000-12-22 |
2002-06-27 |
Bayer Ag |
Verfahren zur Herstellung von 1,6-Hexandiolen
|
|
ES2344592T3
(es)
|
2001-01-05 |
2010-09-01 |
Pfizer Inc. |
Anticuerpos frente al receptor del factor de crecimiento similar a la insulina i.
|
|
US6961875B2
(en)
|
2001-03-22 |
2005-11-01 |
International Business Machines Corporation |
Method and apparatus for capturing event traces for debug and analysis
|
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
|
US7034134B2
(en)
|
2001-04-26 |
2006-04-25 |
Bristol-Myers Squibb Company |
Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
|
|
US7074611B2
(en)
|
2001-04-27 |
2006-07-11 |
Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) |
Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof
|
|
JP4115281B2
(ja)
|
2001-05-11 |
2008-07-09 |
キリンファーマ株式会社 |
ヒト抗体λ軽鎖遺伝子を含むヒト人工染色体、および子孫伝達可能な該ヒト人工染色体を含む非ヒト動物
|
|
ATE477280T1
(de)
|
2001-06-28 |
2010-08-15 |
Domantis Ltd |
Doppelspezifischer ligand und dessen verwendung
|
|
CN1671416B
(zh)
|
2001-07-12 |
2013-01-02 |
杰斐逊·富特 |
超人源化抗体
|
|
WO2003062370A2
(en)
|
2001-07-19 |
2003-07-31 |
Perlan Therapeutics, Inc. |
Multimeric proteins and methods of making and using same
|
|
EP1652920B1
(de)
|
2001-10-01 |
2010-08-04 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Verfahren zur Herstellung von Protein-Bibliotheken und zur Selektion von Proteinen daraus
|
|
US20060199204A1
(en)
|
2001-10-05 |
2006-09-07 |
U.S. Epa |
Genetic testing for male factor infertility
|
|
WO2003031656A1
(en)
|
2001-10-05 |
2003-04-17 |
United States Environmental Protection Agency |
Genetic testing for male factor infertility
|
|
WO2003047336A2
(en)
|
2001-11-30 |
2003-06-12 |
Abgenix, Inc. |
TRANSGENIC ANIMALS BEARING HUMAN Igμ LIGHT CHAIN GENES
|
|
GB0130267D0
(en)
|
2001-12-19 |
2002-02-06 |
Neutec Pharma Plc |
Focussed antibody technology
|
|
AU2003214842A1
(en)
|
2002-01-17 |
2003-09-02 |
Albert Einstein College Of Medicine Of Yeshiva University |
Mutations caused by activation-induced cytidine deaminase
|
|
KR20040099264A
(ko)
|
2002-01-18 |
2004-11-26 |
이노비오 에이에스 |
근육내 투여를 위한 이중특이성 항체 ｄｎａ 작제물
|
|
WO2003091424A1
(fr)
|
2002-04-26 |
2003-11-06 |
Chugai Seiyaku Kabushiki Kaisha |
Procede de criblage d'un anticorps agoniste
|
|
US20040023880A1
(en)
|
2002-05-03 |
2004-02-05 |
Gale Nicholas W. |
Methods of inducing formation of functional and organized lymphatic vessels
|
|
WO2003106495A2
(en)
|
2002-06-14 |
2003-12-24 |
Immunomedics, Inc. |
MONOCLONAL ANTIBODY hPAM4
|
|
CN101962408A
(zh)
|
2002-07-12 |
2011-02-02 |
杰斐逊·富特 |
超人源化抗体
|
|
JP4836451B2
(ja)
|
2002-07-18 |
2011-12-14 |
メルス ベー ヴェー |
抗体混合物の組換え生産
|
|
AR042145A1
(es)
|
2002-11-27 |
2005-06-08 |
Dow Agrociences Llc |
Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
|
|
GB0228210D0
(en)
|
2002-12-03 |
2003-01-08 |
Babraham Inst |
Single chain antibodies
|
|
GB0230201D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Retargeting
|
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
EP1439234A1
(en)
|
2003-01-08 |
2004-07-21 |
ARTEMIS Pharmaceuticals GmbH |
Targeted transgenesis using the rosa26 locus
|
|
DE602004021095D1
(de)
|
2003-01-21 |
2009-06-25 |
Chugai Pharmaceutical Co Ltd |
Verfahren zum screening der leichten kette eines antikörpers
|
|
AU2004208031B2
(en)
|
2003-01-28 |
2009-10-08 |
Cellectis |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
|
|
CA2517519A1
(en)
|
2003-03-04 |
2004-09-16 |
Alexion Pharmaceuticals, Inc. |
Vectors used to create hybrid constant regions
|
|
EP1639009B1
(en)
|
2003-05-30 |
2013-02-27 |
Merus B.V. |
Fab library for the preparation of a mixture of antibodies
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
US7205148B2
(en)
|
2003-06-11 |
2007-04-17 |
Regeneron Pharmaceuticals, Inc. |
Genome mutation by intron insertion into an embryonic stem cell genome
|
|
CN1852925A
(zh)
|
2003-07-15 |
2006-10-25 |
人类多克隆治疗公司 |
人源化免疫球蛋白基因座
|
|
US20050153392A1
(en)
|
2003-08-11 |
2005-07-14 |
Roland Buelow |
Transgenesis with humanized immunoglobulin loci
|
|
RU2251699C1
(ru)
|
2003-09-25 |
2005-05-10 |
Киселев Всеволод Иванович |
Способ ранней и доклинической диагностики цервикального рака
|
|
WO2005038001A2
(en)
|
2003-10-14 |
2005-04-28 |
Therapeutic Human Polyclonals, Inc. |
Improved transgenesis by sperm-mediated gene transfer
|
|
DK1709081T3
(da)
|
2004-01-16 |
2011-06-06 |
Regeneron Pharma |
Fusionspolypeptider, der kan aktivere receptorer
|
|
EP1723235B1
(en)
|
2004-02-12 |
2012-06-27 |
The Walter And Eliza Hall Institute Of Medical Research |
Modified cells that co-express blimp1 and a reporter molecule and methods of using the same
|
|
CN1560081A
(zh)
|
2004-02-17 |
2005-01-05 |
大连帝恩生物工程有限公司 |
用能产生人IgGl重链－κ轻链小鼠作为制备人源化单克隆抗体和应用
|
|
US7625549B2
(en)
|
2004-03-19 |
2009-12-01 |
Amgen Fremont Inc. |
Determining the risk of human anti-human antibodies in transgenic mice
|
|
PT1802193E
(pt)
|
2004-10-19 |
2014-06-23 |
Regeneron Pharma |
Método para gerar um murganho homozigótico para uma modificação genética
|
|
WO2006047367A2
(en)
|
2004-10-22 |
2006-05-04 |
Therapeutic Human Polyclonals, Inc. |
Suppression of endogenous immunoglubolin expression in non-human transgenic animals
|
|
CN101132811B
(zh)
*
|
2004-10-22 |
2012-05-30 |
米迪缪尼有限公司 |
抗hmgb1的高亲和力抗体及其用法
|
|
CA2589208A1
(en)
|
2004-11-26 |
2006-06-01 |
Frankgen Biotechnologie Ag |
Gene trap cassettes for random and targeted conditional gene inactivation
|
|
EP1662005A1
(en)
|
2004-11-26 |
2006-05-31 |
FrankGen Biotechnologie AG |
Enhancer-containing gene trap vectors for random and targeted gene trapping
|
|
US20110041370A1
(en)
|
2005-04-21 |
2011-02-24 |
Saint Andre M |
Face sheet, identification band, and related methods
|
|
WO2006117699A2
(en)
|
2005-04-29 |
2006-11-09 |
Innate Pharma |
Transgenic animals and methods of making recombinant antibodies
|
|
MX2007014139A
(es)
|
2005-05-14 |
2008-10-09 |
Univ Fudan |
Piggybac como una herramienta para manipulacion genetica y analisis en vertebrados.
|
|
PL2002003T3
(pl)
|
2005-05-27 |
2016-06-30 |
Ospedale San Raffaele Srl |
Wektor genetyczny zawierający mi-RNA
|
|
PL1739691T3
(pl)
|
2005-06-30 |
2009-06-30 |
Borealis Tech Oy |
Zewnętrzne osłony dla kabli elektroenergetycznych lub telekomunikacyjnych
|
|
FR2888850B1
(fr)
|
2005-07-22 |
2013-01-11 |
Pf Medicament |
Nouveaux anticorps anti-igf-ir et leurs applications
|
|
WO2007065433A2
(en)
|
2005-12-05 |
2007-06-14 |
Symphogen A/S |
Anti-orthopoxvirus recombinant polyclonal antibody
|
|
RU2435784C2
(ru)
|
2006-01-25 |
2011-12-10 |
Эрасмус Юниверсити Медикал Сентр Роттердам |
Получение антител из одних тяжелых цепей в трансгенных животных
|
|
GB2434578A
(en)
|
2006-01-26 |
2007-08-01 |
Univ Basel |
Transgenic animals
|
|
US7462759B2
(en)
|
2006-02-03 |
2008-12-09 |
Pioneer Hi-Bred International, Inc. |
Brittle stalk 2 gene family and related methods and uses
|
|
GB0615327D0
(en)
|
2006-03-30 |
2006-09-13 |
Univ Edinburgh |
Culture medium containing kinase inhibitors and uses thereof
|
|
WO2007117410A2
(en)
|
2006-03-31 |
2007-10-18 |
Medarex, Inc. |
Transgenic animals expressing chimeric antibodies for use in preparing human antibodies
|
|
PL2041177T3
(pl)
|
2006-06-02 |
2012-09-28 |
Regeneron Pharma |
Przeciwciała o wysokim powinowactwie przeciw ludzkiemu receptorowi IL 6
|
|
US20090217397A1
(en)
|
2006-06-12 |
2009-08-27 |
Patrick Stern |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
EP2061812A4
(en)
|
2006-08-22 |
2010-06-09 |
G2 Inflammation Pty Ltd |
METHOD FOR THE PRODUCTION OF ANTIBODIES
|
|
EP2064325B1
(en)
|
2006-09-01 |
2011-12-07 |
Therapeutic Human Polyclonals, Inc. |
Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
|
|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
JP2010505418A
(ja)
|
2006-10-02 |
2010-02-25 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
ヒトｉｌ−４受容体に対する高親和性ヒト抗体
|
|
NO347649B1
(no)
|
2006-12-14 |
2024-02-12 |
Regeneron Pharma |
Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse.
|
|
GB0700194D0
(en)
|
2007-01-05 |
2007-02-14 |
Univ Edinburgh |
Humanisation of animals
|
|
WO2008112226A2
(en)
|
2007-03-13 |
2008-09-18 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
EP2134852A4
(en)
|
2007-03-13 |
2010-04-28 |
Nat Jewish Health |
PROCESS FOR THE PRODUCTION OF ANTIBODIES
|
|
GB0706628D0
(en)
|
2007-04-04 |
2007-05-16 |
Univ Erasmus |
Germ-line manipulation 1
|
|
KR101703299B1
(ko)
|
2007-06-01 |
2017-02-06 |
오픈 모노클로날 테크놀로지, 인코포레이티드 |
내생적 면역글로불린 유전자를 억제하고 트랜스제닉 인간 이디오타입 항체를 생산하기 위한 방법 및 조성물
|
|
WO2009013620A2
(en)
|
2007-06-11 |
2009-01-29 |
Erasmus University Medical Center Rotterdam |
Homologous recombination
|
|
ITMI20071522A1
(it)
|
2007-07-27 |
2009-01-28 |
Areta Internat S R L |
Vaccino idiotipico
|
|
WO2009097006A2
(en)
|
2007-08-10 |
2009-08-06 |
Medarex, Inc. |
Hco32 and hco27 and related examples
|
|
CN103298935A
(zh)
|
2007-08-15 |
2013-09-11 |
阿穆尼克斯公司 |
用于改善生物活性多肽性能的组合物和方法
|
|
CA2697448C
(en)
|
2007-08-30 |
2019-06-11 |
The Burnet Institute |
Dendritic cell marker and uses thereof
|
|
JP5933894B2
(ja)
|
2007-09-14 |
2016-06-15 |
アディマブ， エルエルシー |
合理的に設計された、合成抗体ライブラリおよびその使用
|
|
EP2050764A1
(en)
|
2007-10-15 |
2009-04-22 |
sanofi-aventis |
Novel polyvalent bispecific antibody format and uses thereof
|
|
WO2009051974A1
(en)
|
2007-10-17 |
2009-04-23 |
Nuvelo, Inc. |
Antibodes to cll-1
|
|
US7659842B2
(en)
|
2007-10-24 |
2010-02-09 |
Infineon Technologies Ag |
Quantization error reduction in PWM full-MASH converters
|
|
KR101615935B1
(ko)
|
2007-12-14 |
2016-04-28 |
노보 노르디스크 에이/에스 |
인간 ｎｋｇ2ｄ에 대한 항체 및 그것의 용도
|
|
PL2235064T3
(pl)
|
2008-01-07 |
2016-06-30 |
Amgen Inc |
Sposób otrzymywania cząsteczek przeciwciał z heterodimerycznymi fc z zastosowaniem kierujących efektów elektrostatycznych
|
|
WO2009114400A1
(en)
|
2008-03-07 |
2009-09-17 |
Regeneron Pharmaceuticals, Inc. |
Es cell-derived mice from diploid host embryo injection
|
|
CA2721231C
(en)
|
2008-04-14 |
2015-10-06 |
Innovative Targeting Solutions Inc. |
Sequence diversity generation in immunoglobulins
|
|
EP2669298A3
(en)
|
2008-05-23 |
2014-02-26 |
Ablexis, LLC |
Single variable immunoglobulin domain comprising VL-DH-JL
|
|
CA2729095C
(en)
|
2008-06-27 |
2018-12-04 |
Merus B.V. |
Method for producing a transgenic murine mammal
|
|
DK2346994T3
(da)
|
2008-09-30 |
2022-02-28 |
Ablexis Llc |
Knock-in-mus til fremstilling af kimære antistoffer
|
|
DK2356270T3
(da)
|
2008-11-07 |
2016-12-12 |
Fabrus Llc |
Kombinatoriske antistofbiblioteker og anvendelser deraf
|
|
US8497325B2
(en)
|
2008-12-15 |
2013-07-30 |
Exxonmobil Chemical Patents Inc. |
Thermoplastic polyolefin blends and films therefrom
|
|
MX2011007660A
(es)
|
2008-12-18 |
2011-08-17 |
Kingdon Craig R |
Animales transgenicos no humanos que expresan anticuerpos humanizados y usos de los mismos.
|
|
JP2012518398A
(ja)
|
2009-02-24 |
2012-08-16 |
グラクソ グループ リミテッド |
抗原結合性構築物
|
|
GB0905023D0
(en)
|
2009-03-24 |
2009-05-06 |
Univ Erasmus Medical Ct |
Binding molecules
|
|
WO2010128897A1
(en)
|
2009-05-07 |
2010-11-11 |
Volvo Construction Equipment Ab |
A working machine and a method for operating a working machine
|
|
US8685896B2
(en)
|
2009-05-29 |
2014-04-01 |
Morphosys Ag |
Collection and methods for its use
|
|
MY152963A
(en)
|
2009-06-26 |
2014-12-15 |
Regeneron Pharma |
Readily isolated bispecific antibodies with native immunoglobulin format
|
|
CN102638971B
(zh)
|
2009-07-08 |
2015-10-07 |
科马布有限公司 |
动物模型及治疗分子
|
|
RU2425880C2
(ru)
*
|
2009-07-30 |
2011-08-10 |
Учреждение Российской академии наук Институт общей генетики им. Н.И. Вавилова РАН |
Способ получения трансгенных мышей
|
|
NZ600002A
(en)
|
2009-11-17 |
2014-08-29 |
Sanford Applied Biosciences L L C |
Human artificial chromosome vector
|
|
SI2954779T1
(sl)
|
2009-12-10 |
2019-06-28 |
Regeneron Pharmaceuticals, Inc. |
Miši, ki proizvajajo težkoverižna protitelesa
|
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
|
KR101829691B1
(ko)
|
2010-02-08 |
2018-02-19 |
리제너론 파마슈티칼스 인코포레이티드 |
일반적인 경쇄 마우스
|
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
|
US20130185821A1
(en)
|
2010-02-08 |
2013-07-18 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
US20120021409A1
(en)
|
2010-02-08 |
2012-01-26 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
WO2011143545A1
(en)
|
2010-05-14 |
2011-11-17 |
Rinat Neuroscience Corporation |
Heterodimeric proteins and methods for producing and purifying them
|
|
CN105695415A
(zh)
|
2010-06-17 |
2016-06-22 |
科马布有限公司 |
动物模型及治疗分子
|
|
KR101970944B1
(ko)
|
2010-06-22 |
2019-04-23 |
리제너론 파아마슈티컬스, 인크. |
하이브리드 경쇄 마우스
|
|
IL315833A
(en)
|
2010-08-02 |
2024-11-01 |
Regeneron Pharma |
Mice producing binding proteins containing VL regions
|
|
WO2012063048A1
(en)
|
2010-11-08 |
2012-05-18 |
Kymab Limited |
Cells & vertebrates for enhanced somatic hypermutation and class switch recombination
|
|
MX375115B
(es)
|
2011-02-25 |
2025-03-06 |
Regeneron Pharma |
Ratones de una desintegrina y metaloproteasa 6 (adam6).
|
|
CN107602696B
(zh)
*
|
2011-08-05 |
2022-05-13 |
瑞泽恩制药公司 |
人源化的通用轻链小鼠
|
|
CN102957766A
(zh)
|
2011-08-18 |
2013-03-06 |
佛山正能光电有限公司 |
具可卸式相机模块的行动装置
|
|
JP2014531452A
(ja)
|
2011-09-19 |
2014-11-27 |
カイマブ・リミテッド |
動物、レパートリーおよび方法
|
|
EP2758535B1
(en)
|
2011-09-19 |
2016-11-09 |
Kymab Limited |
Antibodies, variable domains&chains tailored for human use
|
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
|
WO2013045916A1
(en)
|
2011-09-26 |
2013-04-04 |
Kymab Limited |
Chimaeric surrogate light chains (slc) comprising human vpreb
|
|
MX355062B
(es)
|
2011-10-17 |
2018-04-03 |
Regeneron Pharma |
Ratones con cadena pesada de inmunoglobulina restringida.
|
|
GB2496375A
(en)
|
2011-10-28 |
2013-05-15 |
Kymab Ltd |
A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
|
|
GB201122047D0
(en)
|
2011-12-21 |
2012-02-01 |
Kymab Ltd |
Transgenic animals
|
|
US9253965B2
(en)
|
2012-03-28 |
2016-02-09 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
SI2793567T1
(sl)
|
2011-12-20 |
2019-05-31 |
Regeneron Pharmaceuticals, Inc. |
Humanizirane lahkoverižne miši
|
|
EP3912465A1
(en)
|
2012-02-01 |
2021-11-24 |
Regeneron Pharmaceuticals, Inc. |
Humanized rodents that express heavy chains containing vl domains
|
|
KR20200126007A
(ko)
|
2012-04-20 |
2020-11-05 |
메뤼스 엔.페. |
Ig-유사 분자의 제조방법 및 제조수단
|
|
EP3912464A1
(en)
|
2012-06-12 |
2021-11-24 |
Regeneron Pharmaceuticals, Inc. |
Humanized non-human animals with restricted immunoglobulin heavy chain loci
|
|
PT3501272T
(pt)
|
2013-03-13 |
2023-03-29 |
Regeneron Pharma |
Murganhos que expressam um repertório limitado de cadeia leve de imunoglobulina
|
|
MX2015012540A
(es)
|
2013-03-13 |
2016-04-19 |
Regeneron Pharma |
Ratón de cadena ligera común.
|