JP2013520996A5 - - Google Patents

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JP2013520996A5
JP2013520996A5 JP2012556192A JP2012556192A JP2013520996A5 JP 2013520996 A5 JP2013520996 A5 JP 2013520996A5 JP 2012556192 A JP2012556192 A JP 2012556192A JP 2012556192 A JP2012556192 A JP 2012556192A JP 2013520996 A5 JP2013520996 A5 JP 2013520996A5
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amino acid
monoclonal antibody
isolated
acid sequence
seq
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JP2012556192A
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JP2013520996A (ja
JP6025570B2 (ja
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Priority claimed from PCT/US2011/026766 external-priority patent/WO2011109452A1/en
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Publication of JP2013520996A5 publication Critical patent/JP2013520996A5/ja
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JP2012556192A 2010-03-01 2011-03-01 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体 Expired - Fee Related JP6025570B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30929010P 2010-03-01 2010-03-01
US61/309,290 2010-03-01
PCT/US2011/026766 WO2011109452A1 (en) 2010-03-01 2011-03-01 Optimized Monoclonal Antibodies against Tissue Factor Pathway Inhibitor (TFPI)

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JP2016199718A Division JP6475679B2 (ja) 2010-03-01 2016-10-11 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体

Publications (3)

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JP2013520996A JP2013520996A (ja) 2013-06-10
JP2013520996A5 true JP2013520996A5 (enExample) 2014-04-17
JP6025570B2 JP6025570B2 (ja) 2016-11-16

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JP2012556192A Expired - Fee Related JP6025570B2 (ja) 2010-03-01 2011-03-01 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体
JP2016199718A Expired - Fee Related JP6475679B2 (ja) 2010-03-01 2016-10-11 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体
JP2019016811A Expired - Fee Related JP6684369B2 (ja) 2010-03-01 2019-02-01 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体
JP2020057005A Withdrawn JP2020115868A (ja) 2010-03-01 2020-03-27 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体

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JP2016199718A Expired - Fee Related JP6475679B2 (ja) 2010-03-01 2016-10-11 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体
JP2019016811A Expired - Fee Related JP6684369B2 (ja) 2010-03-01 2019-02-01 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体
JP2020057005A Withdrawn JP2020115868A (ja) 2010-03-01 2020-03-27 組織因子経路インヒビター(tfpi)に対する最適化されたモノクローナル抗体

Country Status (37)

Country Link
US (3) USRE47150E1 (enExample)
EP (2) EP3345615B1 (enExample)
JP (4) JP6025570B2 (enExample)
KR (4) KR101903931B1 (enExample)
CN (5) CN105001335B (enExample)
AU (1) AU2011223710B2 (enExample)
BR (1) BR112012022258A2 (enExample)
CA (3) CA2791685C (enExample)
CL (2) CL2012002415A1 (enExample)
CO (1) CO6620068A2 (enExample)
CR (1) CR20120453A (enExample)
CU (1) CU23982B1 (enExample)
CY (2) CY1119410T1 (enExample)
DK (2) DK2542257T3 (enExample)
DO (1) DOP2012000239A (enExample)
EA (2) EA201892184A1 (enExample)
EC (2) ECSP12012134A (enExample)
ES (2) ES2765418T3 (enExample)
GT (1) GT201200252A (enExample)
HK (2) HK1232232A1 (enExample)
HR (2) HRP20171472T1 (enExample)
HU (2) HUE047173T2 (enExample)
IL (3) IL221551B (enExample)
LT (2) LT3345615T (enExample)
ME (2) ME03578B (enExample)
MX (2) MX2012010198A (enExample)
MY (1) MY174760A (enExample)
NZ (2) NZ602115A (enExample)
PE (1) PE20160538A1 (enExample)
PH (4) PH12012501742A1 (enExample)
PL (2) PL3345615T3 (enExample)
PT (2) PT2542257T (enExample)
RS (2) RS59830B1 (enExample)
SG (3) SG183443A1 (enExample)
SI (2) SI2542257T1 (enExample)
SM (1) SMT201700454T1 (enExample)
WO (1) WO2011109452A1 (enExample)

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JP6170903B2 (ja) * 2011-04-01 2017-07-26 バイエル・ヘルスケア・エルエルシーBayer HealthCare LLC 組織因子経路インヒビター(tfpi)に対するモノクローナル抗体
CN107266574A (zh) * 2012-03-30 2017-10-20 拜尔健康护理有限责任公司 蛋白酶调节的抗体
US9592297B2 (en) * 2012-08-31 2017-03-14 Bayer Healthcare Llc Antibody and protein formulations
CN113788897A (zh) * 2013-03-15 2021-12-14 拜尔健康护理有限责任公司 改善药代动力学的具有跨pH范围差异结合的抗TFPI抗体变体
WO2014144689A1 (en) * 2013-03-15 2014-09-18 Bayer Healthcare Llc Pro-drug antibodies against tissue factor pathway inhibitor
CN107428838B (zh) * 2015-02-25 2021-01-01 财团法人牧岩生命科学研究所 结合tfpi的新型抗体以及包含所述抗体的组合物
KR20230074843A (ko) 2015-08-19 2023-05-31 화이자 인코포레이티드 조직 인자 경로 억제제 항체 및 그의 용도
KR102337683B1 (ko) * 2018-09-21 2021-12-13 주식회사 녹십자 고효율 항-tfpi 항체 조성물
JP7289913B2 (ja) * 2018-10-11 2023-06-12 ファイザー・インク Tfpiアンタゴニストのための投薬レジメン
KR102692277B1 (ko) * 2019-03-11 2024-08-05 현대자동차주식회사 상용 전기차용 모터 마운트
CN112442127A (zh) * 2019-08-29 2021-03-05 苏州康宁杰瑞生物科技有限公司 针对tfpi的单克隆抗体
EP4245311A4 (en) * 2020-11-13 2024-10-30 Hanmi Pharm. Co., Ltd. USE OF A THERAPEUTIC ENZYMFUSION PROTEIN FOR THE PREVENTION AND TREATMENT OF KIDNEY DISEASE CAUSED BY OR ASSOCIATED WITH FABRY DISEASE
CN117285632A (zh) * 2022-06-17 2023-12-26 安源医药科技(上海)有限公司 针对tfpi的单克隆抗体及其用途

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