JP2016507470A5 - - Google Patents
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- Publication number
- JP2016507470A5 JP2016507470A5 JP2015540879A JP2015540879A JP2016507470A5 JP 2016507470 A5 JP2016507470 A5 JP 2016507470A5 JP 2015540879 A JP2015540879 A JP 2015540879A JP 2015540879 A JP2015540879 A JP 2015540879A JP 2016507470 A5 JP2016507470 A5 JP 2016507470A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- antigen
- seq
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261723137P | 2012-11-06 | 2012-11-06 | |
| US61/723,137 | 2012-11-06 | ||
| US201361782405P | 2013-03-14 | 2013-03-14 | |
| US61/782,405 | 2013-03-14 | ||
| PCT/US2013/068624 WO2014074540A2 (en) | 2012-11-06 | 2013-11-06 | Antibodies to s. aureus surface determinants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019011283A Division JP2019089801A (ja) | 2012-11-06 | 2019-01-25 | S.アウレウス(S.aureus)表面決定基に対する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016507470A JP2016507470A (ja) | 2016-03-10 |
| JP2016507470A5 true JP2016507470A5 (enExample) | 2016-12-22 |
| JP6694269B2 JP6694269B2 (ja) | 2020-05-13 |
Family
ID=50685304
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015540879A Active JP6694269B2 (ja) | 2012-11-06 | 2013-11-06 | S.アウレウス(S.aureus)表面決定基に対する抗体 |
| JP2019011283A Withdrawn JP2019089801A (ja) | 2012-11-06 | 2019-01-25 | S.アウレウス(S.aureus)表面決定基に対する抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019011283A Withdrawn JP2019089801A (ja) | 2012-11-06 | 2019-01-25 | S.アウレウス(S.aureus)表面決定基に対する抗体 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US9879070B2 (enExample) |
| EP (2) | EP2917360B1 (enExample) |
| JP (2) | JP6694269B2 (enExample) |
| KR (1) | KR102288394B1 (enExample) |
| CN (2) | CN104968797B (enExample) |
| AU (2) | AU2013341361A1 (enExample) |
| BR (1) | BR112015010125A2 (enExample) |
| CA (1) | CA2890427C (enExample) |
| DK (1) | DK2917360T3 (enExample) |
| ES (1) | ES2776179T3 (enExample) |
| HU (1) | HUE049012T2 (enExample) |
| MX (2) | MX375324B (enExample) |
| PL (1) | PL2917360T3 (enExample) |
| RU (1) | RU2698131C2 (enExample) |
| SG (2) | SG10201703678TA (enExample) |
| WO (1) | WO2014074540A2 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2673373T (pt) * | 2011-02-08 | 2018-12-05 | Medimmune Llc | Anticorpos que ligam especificamente a toxina alfa de staphylococcus aureus e métodos de utilização |
| RU2014100111A (ru) | 2011-06-10 | 2015-07-20 | МЕДИММЬЮН, ЭлЭлСи | МОЛЕКУЛЫ, СВЯЗЫВАЮЩИЕСЯ С Psl Pseudomonas, И ПУТИ ИХ ПРИМЕНЕНИЯ |
| HRP20201370T1 (hr) | 2011-11-07 | 2020-11-27 | Medimmune Limited | Kombinacijske terapije koje koriste anti-pseudomonas psl i pcrv vezujuće molekule |
| WO2013096948A1 (en) | 2011-12-23 | 2013-06-27 | Lydon Nicholas B | Immunoglobulins and variants directed against pathogenic microbes |
| US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| BR112015010125A2 (pt) * | 2012-11-06 | 2017-08-22 | Medimmune Llc | Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente |
| KR20210083389A (ko) | 2012-11-06 | 2021-07-06 | 메디뮨 엘엘씨 | 에스.아우레우스 연관 질병의 치료 방법 |
| WO2015187779A1 (en) * | 2014-06-03 | 2015-12-10 | Xbiotech, Inc. | Compositions and methods for treating and preventing staphylococcus aureus infections |
| TWI719938B (zh) | 2014-06-19 | 2021-03-01 | 美商麥迪紐有限責任公司 | 多重細菌感染之治療 |
| US20180017559A1 (en) * | 2014-08-12 | 2018-01-18 | Arsanis Biosciences Gmbh | Predicting s. aureus disease |
| WO2016073860A1 (en) * | 2014-11-06 | 2016-05-12 | Medimmune, Llc | Binding molecules specific for staphylococcus protein a and uses thereof |
| FR3033333A1 (fr) * | 2015-03-06 | 2016-09-09 | Commissariat Energie Atomique | Procede et dispositif pour detecter en temps reel un compose secrete et la cible secretrice ainsi que leurs utilisations |
| CN107873034A (zh) * | 2015-04-17 | 2018-04-03 | 阿尔萨尼斯生物科学有限责任公司 | 抗金黄色葡萄球菌抗体组合制剂 |
| WO2017075188A2 (en) * | 2015-10-30 | 2017-05-04 | Medimmune, Llc | Methods of using anti-alpha toxin antibody |
| CN105424930A (zh) * | 2015-11-23 | 2016-03-23 | 天津科技大学 | 一种快速检测金黄色葡萄球菌的方法 |
| CA3076632A1 (en) * | 2017-09-29 | 2019-04-04 | Regeneron Pharmaceuticals, Inc. | Bispecific antigen-binding molecules that bind a staphylococcus target antigen and a complement component and uses thereof |
| JP7525471B2 (ja) | 2018-07-24 | 2024-07-30 | メディミューン,エルエルシー | S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体 |
| TWI895248B (zh) | 2018-10-09 | 2025-09-01 | 美商麥迪紐有限責任公司 | 針對金黃色葡萄球菌白血球毒素的抗體 |
| BR112021006622A2 (pt) | 2018-10-09 | 2021-07-20 | Medimmune, Llc | combinações de anticorpos anti-staphylococcus aureus |
| KR20210126641A (ko) | 2019-02-12 | 2021-10-20 | 리제너론 파아마슈티컬스, 인크. | 보체 및 표적 항원에 결합하기 위해 이중 특이적 항체를 사용하는 조성물 및 방법 |
| CN113811544A (zh) | 2019-03-13 | 2021-12-17 | 免疫医疗有限责任公司 | 减少定殖患者中的金黄色葡萄球菌感染 |
| WO2020210650A1 (en) | 2019-04-12 | 2020-10-15 | Medimmune, Llc | Neutralization of tgf-beta or alpha-v-beta-8 integrin for s. aureus infections |
| CN112538112B (zh) * | 2019-09-20 | 2023-10-27 | 迈威(上海)生物科技股份有限公司 | 抗α-溶血素的抗体及其应用 |
| KR102504175B1 (ko) * | 2020-06-17 | 2023-02-28 | (주)옵토레인 | 항체의 항원 결합 부위에 결합하는 펩타이드, 이를 이용한 약물 복합체, 바이오센서 및 분석 방법 |
| KR102397684B1 (ko) * | 2019-12-09 | 2022-05-13 | (주)옵토레인 | 항체의 항원 결합 부위에 결합하는 펩티드 및 이를 이용한 분석 방법 |
| KR102674109B1 (ko) * | 2021-01-14 | 2024-06-12 | (주)옵토레인 | 스위칭 펩티드, 이를 포함하는 면역분석 장치 및 이를 이용한 면역분석 방법 |
| KR102674098B1 (ko) * | 2021-01-14 | 2024-06-12 | (주)옵토레인 | 스위칭 펩티드 및 이를 이용한 멀티플렉스 면역분석 방법 |
| KR102674120B1 (ko) * | 2021-01-18 | 2024-06-12 | (주)옵토레인 | 스위칭 펩티드 및 이를 이용한 면역분석 방법 |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2017198A (en) * | 1931-10-17 | 1935-10-15 | Anglada Motor Corp | Cuff valve engine |
| US20030044772A1 (en) | 1997-08-04 | 2003-03-06 | Applied Molecular Evolution [Formerly Ixsys] | Methods for identifying ligand specific binding molecules |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| US7396917B2 (en) * | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
| US7214786B2 (en) * | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| PT1377314E (pt) * | 2001-01-26 | 2012-01-02 | Inhibitex Inc | Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções |
| KR20060034231A (ko) | 2003-06-06 | 2006-04-21 | 메디뮨 인코포레이티드 | 암의 진단, 치료 및 예방에 있어서의 epha4 및epha4 조정제의 용도 |
| AU2004266242A1 (en) | 2003-08-12 | 2005-03-03 | Dyax Corp. | Tie1-binding ligands |
| CA2575791A1 (en) * | 2004-08-03 | 2006-02-16 | Dyax Corp. | Hk1-binding proteins |
| US20080050361A1 (en) | 2004-10-25 | 2008-02-28 | Heinrichs David E | Staphylococcus aureas specific anti-infectives |
| WO2007101441A1 (en) | 2006-03-06 | 2007-09-13 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| US7910703B2 (en) * | 2006-03-10 | 2011-03-22 | Zymogenetics, Inc. | Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use |
| US20080131457A1 (en) * | 2006-06-12 | 2008-06-05 | Nabi Biopharmaceuticals | Use of alpha-toxin for treating and preventing staphylococcus infections |
| CA2667788A1 (en) * | 2006-10-30 | 2008-12-18 | The University Of Western Ontario | Staphylococcus aureus specific anti-infectives |
| US9526774B1 (en) * | 2006-11-06 | 2016-12-27 | Microvax, Llc | Methods and compositions for suppressing virulence of methicillin resistant Staphylococcus aureus |
| SG188102A1 (en) * | 2008-01-31 | 2013-03-28 | Trinity College Dublin | Treatment of microbial infections |
| EP2291196A4 (en) * | 2008-05-12 | 2012-05-30 | Strox Biopharmaceuticals Llc | FOR STAPHYLOCOCCUS AUREUS SPECIFIC ANTIBODY PREPARATIONS |
| WO2010005513A2 (en) * | 2008-06-30 | 2010-01-14 | The Texas A&M University System | Crystal structure of staphylococcus aureus clumping factor a in complex with fibrinogen derived peptide and uses thereof |
| EP2341929B1 (en) * | 2008-10-06 | 2017-01-25 | University Of Chicago | Compositions and methods related to bacterial emp proteins |
| WO2011019423A2 (en) * | 2009-05-20 | 2011-02-17 | Schering Corporation | Modulation of pilr receptors to treat microbial infections |
| SA110310528B1 (ar) * | 2009-06-22 | 2014-07-02 | Wyeth Llc | التركيبات المولدة للمناعة لأنتيجينات ستافيلوكوكس أوريس |
| JP6192294B2 (ja) * | 2009-07-15 | 2017-09-06 | エーアイエムエム セラピューティクス ベー.フェー. | グラム陽性菌特異的結合化合物 |
| GB0913680D0 (en) * | 2009-08-05 | 2009-09-16 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| EP2284193A1 (en) * | 2009-08-10 | 2011-02-16 | Kenta Biotech AG | Human monoclonal antibody against S. aureus derived apha-toxin and its use in treating or preventing abscess formation |
| WO2011079308A2 (en) * | 2009-12-23 | 2011-06-30 | Emergent Product Development Seattle, Llc | Compositions comprising tnf-alpha and il-6 antagonists and methods of use thereof |
| EP2555794A4 (en) * | 2010-04-05 | 2014-01-15 | Univ Chicago | COMPOSITIONS AND METHODS RELATING TO PROTEIN A (SPA) ANTIBODIES AS IMMUNE REACTION AMPLIFIERS |
| EP2614074A1 (en) * | 2010-09-09 | 2013-07-17 | The University of Chicago | Methods and compositions involving protective staphylococcal antigens |
| US20120202047A1 (en) | 2011-02-07 | 2012-08-09 | Baker Hughes Incorporated | Nano-coatings for articles |
| PT2673373T (pt) * | 2011-02-08 | 2018-12-05 | Medimmune Llc | Anticorpos que ligam especificamente a toxina alfa de staphylococcus aureus e métodos de utilização |
| BR112014003315A2 (pt) * | 2011-08-15 | 2017-03-01 | Univ Chicago | composições e métodos relacionados a anticorpos para a proteína a estafilocócica |
| RS60499B1 (sr) * | 2011-12-20 | 2020-08-31 | Medimmune Llc | Modifikovani polipeptidi za bispecifične skelete antitela |
| JP6670106B2 (ja) * | 2012-04-26 | 2020-03-18 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | ブドウ球菌コアグラーゼ抗原およびその使用方法 |
| BR112015010125A2 (pt) * | 2012-11-06 | 2017-08-22 | Medimmune Llc | Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente |
| KR20210083389A (ko) * | 2012-11-06 | 2021-07-06 | 메디뮨 엘엘씨 | 에스.아우레우스 연관 질병의 치료 방법 |
| CA2898472C (en) * | 2013-02-15 | 2023-03-07 | Immunomedics, Inc. | Chimeric and humanized anti-histone antibodies |
| WO2015057893A2 (en) * | 2013-10-15 | 2015-04-23 | The Texas A&M University System | Compositions and the use of a fibrinogn binding motif presence in efb and coa for vaccine against staphylococcus aureus and drug delivery |
| WO2015106226A2 (en) * | 2014-01-10 | 2015-07-16 | University Of Rochester | Diagnostic device and method for detection of staphylococcus infection |
| WO2015112895A2 (en) * | 2014-01-24 | 2015-07-30 | Church William R | Antibody specific to staphylococcus aureus, therapeutic method and detection method using same |
| WO2015187779A1 (en) * | 2014-06-03 | 2015-12-10 | Xbiotech, Inc. | Compositions and methods for treating and preventing staphylococcus aureus infections |
| TWI719938B (zh) * | 2014-06-19 | 2021-03-01 | 美商麥迪紐有限責任公司 | 多重細菌感染之治療 |
| WO2016073860A1 (en) * | 2014-11-06 | 2016-05-12 | Medimmune, Llc | Binding molecules specific for staphylococcus protein a and uses thereof |
| CN107873034A (zh) | 2015-04-17 | 2018-04-03 | 阿尔萨尼斯生物科学有限责任公司 | 抗金黄色葡萄球菌抗体组合制剂 |
| WO2017075188A2 (en) * | 2015-10-30 | 2017-05-04 | Medimmune, Llc | Methods of using anti-alpha toxin antibody |
| EP3448427A1 (en) * | 2016-04-29 | 2019-03-06 | CureVac AG | Rna encoding an antibody |
| BR112018077540A2 (pt) * | 2016-07-08 | 2019-10-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | vírus quimérico da dengue/zika como vacinas de zika vírus vivo atenuado |
| JP7525471B2 (ja) * | 2018-07-24 | 2024-07-30 | メディミューン,エルエルシー | S.アウレウス(S.aureus)クランピング因子A(ClfA)に対する抗体 |
| BR112021006622A2 (pt) * | 2018-10-09 | 2021-07-20 | Medimmune, Llc | combinações de anticorpos anti-staphylococcus aureus |
| TWI895248B (zh) * | 2018-10-09 | 2025-09-01 | 美商麥迪紐有限責任公司 | 針對金黃色葡萄球菌白血球毒素的抗體 |
| CN113811544A (zh) * | 2019-03-13 | 2021-12-17 | 免疫医疗有限责任公司 | 减少定殖患者中的金黄色葡萄球菌感染 |
-
2013
- 2013-11-06 BR BR112015010125A patent/BR112015010125A2/pt not_active Application Discontinuation
- 2013-11-06 RU RU2015121624A patent/RU2698131C2/ru active
- 2013-11-06 WO PCT/US2013/068624 patent/WO2014074540A2/en not_active Ceased
- 2013-11-06 MX MX2015005477A patent/MX375324B/es active IP Right Grant
- 2013-11-06 CN CN201380057603.9A patent/CN104968797B/zh active Active
- 2013-11-06 AU AU2013341361A patent/AU2013341361A1/en not_active Abandoned
- 2013-11-06 DK DK13852597.7T patent/DK2917360T3/da active
- 2013-11-06 KR KR1020157014912A patent/KR102288394B1/ko active Active
- 2013-11-06 JP JP2015540879A patent/JP6694269B2/ja active Active
- 2013-11-06 ES ES13852597T patent/ES2776179T3/es active Active
- 2013-11-06 SG SG10201703678TA patent/SG10201703678TA/en unknown
- 2013-11-06 CN CN201811621407.0A patent/CN109553681A/zh active Pending
- 2013-11-06 US US14/440,748 patent/US9879070B2/en active Active
- 2013-11-06 EP EP13852597.7A patent/EP2917360B1/en active Active
- 2013-11-06 PL PL13852597T patent/PL2917360T3/pl unknown
- 2013-11-06 EP EP19211610.1A patent/EP3640338A1/en active Pending
- 2013-11-06 SG SG11201503232TA patent/SG11201503232TA/en unknown
- 2013-11-06 HU HUE13852597A patent/HUE049012T2/hu unknown
- 2013-11-06 CA CA2890427A patent/CA2890427C/en active Active
-
2015
- 2015-04-29 MX MX2022008079A patent/MX2022008079A/es unknown
-
2018
- 2018-01-25 US US15/880,157 patent/US10730934B2/en active Active
- 2018-10-04 AU AU2018241107A patent/AU2018241107B2/en active Active
-
2019
- 2019-01-25 JP JP2019011283A patent/JP2019089801A/ja not_active Withdrawn
-
2020
- 2020-07-09 US US16/925,129 patent/US11447543B2/en active Active
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