JP2012504634A5 - - Google Patents

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Publication number
JP2012504634A5
JP2012504634A5 JP2011530173A JP2011530173A JP2012504634A5 JP 2012504634 A5 JP2012504634 A5 JP 2012504634A5 JP 2011530173 A JP2011530173 A JP 2011530173A JP 2011530173 A JP2011530173 A JP 2011530173A JP 2012504634 A5 JP2012504634 A5 JP 2012504634A5
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JP
Japan
Prior art keywords
antibody
seq
amino acid
acid sequence
hvr
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JP2011530173A
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English (en)
Japanese (ja)
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JP5710487B2 (ja
JP2012504634A (ja
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Priority claimed from PCT/US2009/059028 external-priority patent/WO2010039832A1/en
Publication of JP2012504634A publication Critical patent/JP2012504634A/ja
Publication of JP2012504634A5 publication Critical patent/JP2012504634A5/ja
Application granted granted Critical
Publication of JP5710487B2 publication Critical patent/JP5710487B2/ja
Active legal-status Critical Current
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JP2011530173A 2008-10-01 2009-09-30 抗notch2抗体および使用方法 Active JP5710487B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10191708P 2008-10-01 2008-10-01
US61/101,917 2008-10-01
PCT/US2009/059028 WO2010039832A1 (en) 2008-10-01 2009-09-30 Anti-notch2 antibodies and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015042089A Division JP2015145379A (ja) 2008-10-01 2015-03-04 抗notch2抗体および使用方法

Publications (3)

Publication Number Publication Date
JP2012504634A JP2012504634A (ja) 2012-02-23
JP2012504634A5 true JP2012504634A5 (enExample) 2012-11-15
JP5710487B2 JP5710487B2 (ja) 2015-04-30

Family

ID=41349057

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011530173A Active JP5710487B2 (ja) 2008-10-01 2009-09-30 抗notch2抗体および使用方法
JP2015042089A Pending JP2015145379A (ja) 2008-10-01 2015-03-04 抗notch2抗体および使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015042089A Pending JP2015145379A (ja) 2008-10-01 2015-03-04 抗notch2抗体および使用方法

Country Status (18)

Country Link
US (5) US8404239B2 (enExample)
EP (1) EP2334331B1 (enExample)
JP (2) JP5710487B2 (enExample)
KR (1) KR101712214B1 (enExample)
CN (1) CN102170909B (enExample)
AR (1) AR073717A1 (enExample)
AU (1) AU2009298569A1 (enExample)
BR (1) BRPI0913827A2 (enExample)
CA (1) CA2736429A1 (enExample)
CL (1) CL2011000711A1 (enExample)
ES (1) ES2541726T3 (enExample)
IL (1) IL211623A0 (enExample)
MX (1) MX2011002928A (enExample)
PE (1) PE20120080A1 (enExample)
RU (1) RU2580029C2 (enExample)
TW (1) TW201018484A (enExample)
WO (1) WO2010039832A1 (enExample)
ZA (1) ZA201101651B (enExample)

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AU2009298569A1 (en) * 2008-10-01 2010-04-08 Genentech, Inc. Anti-Notch2 antibodies and methods of use
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US8906649B2 (en) 2010-09-27 2014-12-09 Janssen Biotech, Inc. Antibodies binding human collagen II
US9663573B2 (en) 2011-10-05 2017-05-30 Genentech, Inc. Methods of treating liver conditions using Notch2 antagonists
WO2013173542A1 (en) * 2012-05-16 2013-11-21 Oncomed Pharmaceuticals, Inc. Methods for treating cancer with notch2/3 antibodies
BR112015003032B1 (pt) 2012-08-13 2023-03-28 Genentech, Inc Anticorpos isolados, imunoconjugado, formulação farmacêutica e uso do anticorpo
WO2014141064A1 (en) 2013-03-13 2014-09-18 Novartis Ag Notch2 binding molecules for treating respiratory diseases
US9550829B2 (en) 2013-03-15 2017-01-24 Genentech, Inc. Compositions and methods for diagnosis and treatment of hepatic cancers
WO2015123325A1 (en) 2014-02-12 2015-08-20 Genentech, Inc. Anti-jagged1 antibodies and methods of use
BR112017000130A2 (pt) 2014-07-11 2018-01-09 Genentech Inc método para atenuar a toxicidade associada à inibição da via de notch e método de tratamento do câncer
CN108472201A (zh) * 2015-09-26 2018-08-31 财团法人卫生研究院 用于治疗掉发之方法及组成物
GB201521447D0 (en) 2015-12-04 2016-01-20 Ucb Biopharma Sprl De novo antibody design
WO2018222880A1 (en) * 2017-05-31 2018-12-06 Trustees Of Boston University Mechano-activated control of gene expression
MX2023000617A (es) * 2020-07-17 2023-02-13 Genentech Inc Anticuerpos anti-notch2 y metodos de uso.
WO2024216505A1 (zh) * 2023-04-18 2024-10-24 上海洛启生物医药技术有限公司 抗Notch2纳米抗体及其应用
CN120441700B (zh) * 2023-11-21 2026-02-10 兰州大学第二医院 一种抗人notch2单链抗体、编码基因、试剂盒及其用途
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

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