JP2012502649A5 - - Google Patents

Download PDF

Info

Publication number
JP2012502649A5
JP2012502649A5 JP2011527406A JP2011527406A JP2012502649A5 JP 2012502649 A5 JP2012502649 A5 JP 2012502649A5 JP 2011527406 A JP2011527406 A JP 2011527406A JP 2011527406 A JP2011527406 A JP 2011527406A JP 2012502649 A5 JP2012502649 A5 JP 2012502649A5
Authority
JP
Japan
Prior art keywords
antibody
seq
amino acid
cdr1
cdr2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011527406A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012502649A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2009/051216 external-priority patent/WO2010032059A2/en
Publication of JP2012502649A publication Critical patent/JP2012502649A/ja
Publication of JP2012502649A5 publication Critical patent/JP2012502649A5/ja
Withdrawn legal-status Critical Current

Links

JP2011527406A 2008-09-19 2009-09-18 Cd105を対象とする標的結合剤およびその使用 Withdrawn JP2012502649A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9868508P 2008-09-19 2008-09-19
US61/098,685 2008-09-19
PCT/GB2009/051216 WO2010032059A2 (en) 2008-09-19 2009-09-18 Targeted binding agents directed to cd105 and uses thereof

Publications (2)

Publication Number Publication Date
JP2012502649A JP2012502649A (ja) 2012-02-02
JP2012502649A5 true JP2012502649A5 (enExample) 2012-11-01

Family

ID=41263674

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011527406A Withdrawn JP2012502649A (ja) 2008-09-19 2009-09-18 Cd105を対象とする標的結合剤およびその使用

Country Status (9)

Country Link
US (1) US20100196398A1 (enExample)
EP (1) EP2344541A2 (enExample)
JP (1) JP2012502649A (enExample)
KR (1) KR20110057245A (enExample)
CN (1) CN102388067A (enExample)
AU (1) AU2009294414A1 (enExample)
BR (1) BRPI0918555A2 (enExample)
CA (1) CA2737667A1 (enExample)
WO (1) WO2010032059A2 (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130065723A (ko) 2003-06-27 2013-06-19 암젠 프레몬트 인코포레이티드 상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그 용도
PE20081216A1 (es) 2006-09-01 2008-09-04 Therapeutic Human Polyclonals Inc Expresion mejorada de la inmunoglobulina humana o humanizada en animales transgenicos no humanos
HRP20140049T1 (hr) 2007-01-05 2014-02-28 University Of Zürich Anti beta-amiloid antitijela i njihova upotreba
CN102317316B (zh) 2008-12-19 2014-08-13 帕尼玛制药股份公司 人抗α突触核蛋白自身抗体
US8221753B2 (en) 2009-09-30 2012-07-17 Tracon Pharmaceuticals, Inc. Endoglin antibodies
UA109888C2 (uk) 2009-12-07 2015-10-26 ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
EP2542696B1 (en) 2010-03-01 2016-09-28 Caris Life Sciences Switzerland Holdings GmbH Biomarkers for theranostics
JP2013526852A (ja) 2010-04-06 2013-06-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス 疾患に対する循環バイオマーカー
CA2815181C (en) * 2010-10-27 2020-09-15 William Gleason Richards Dkk1 antibodies and methods of use
US9315582B2 (en) 2011-02-23 2016-04-19 Health Research, Inc. Anti-endoglin antibodies and knockin mice expressing novel human/mouse chimeric endoglin
EA201391248A1 (ru) * 2011-03-01 2014-05-30 Эмджен Инк. Биспецифические связывающие агенты
US9255595B2 (en) * 2011-04-29 2016-02-09 Bae Systems Information And Electronic Systems Integration Inc. Optical dome bezel
SI2723379T1 (sl) 2011-06-23 2019-03-29 Biogen International Neuroscience Gmbh Molekule, ki se vežejo ma anti alfa-sinuklein
WO2013074840A1 (en) * 2011-11-15 2013-05-23 Allergan, Inc. Treatment of dry age related macular degeneration
UA115789C2 (uk) * 2012-09-05 2017-12-26 Трейкон Фармасутікалз, Інк. Композиція антитіла до cd105 та її застосування
CA2966905A1 (en) 2014-11-12 2016-05-19 Tracon Pharmaceuticals, Inc. Anti-endoglin antibodies and uses thereof
US9926375B2 (en) 2014-11-12 2018-03-27 Tracon Pharmaceuticals, Inc. Anti-endoglin antibodies and uses thereof
MA41115A (fr) 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer
CN105821029A (zh) * 2015-01-04 2016-08-03 彭霞 异源融合基因修饰的癌细胞/树突状细胞融合肿瘤疫苗及其制备方法
SG11201802698XA (en) * 2015-10-29 2018-05-30 Hoffmann La Roche Transgenic rabbit with common light chain
CN106928359B (zh) * 2015-12-30 2020-10-13 广西医科大学 一种CD105纳米抗体Nb59
CN106928355B (zh) * 2015-12-30 2020-09-29 广西医科大学 一种CD105纳米抗体Nb184
US10729771B2 (en) 2016-02-10 2020-08-04 Rutgers, The State University Of New Jersey Anti-LAM and anti-PIM6/LAM monoclonal antibodies for diagnosis and treatment of Mycobacterium tuberculosis infections
US20200239587A1 (en) * 2016-06-14 2020-07-30 Cedars-Sinai Medical Center Sensitization of tumors to therapies through endoglin antagonism
CN118370815A (zh) 2017-08-22 2024-07-23 渤健马萨诸塞州股份有限公司 含有抗β淀粉样蛋白抗体的药物组合物
CN108912212B (zh) * 2018-06-28 2019-08-30 中山大学附属口腔医院 一种与cd105特异性结合的多肽及其应用
WO2020106461A2 (en) * 2018-11-08 2020-05-28 Celldex Therapeutics, Inc. Anti-mertk antibodies and methods of use thereof
KR20210095781A (ko) 2020-01-24 2021-08-03 주식회사 에이프릴바이오 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물
WO2021207433A2 (en) * 2020-04-07 2021-10-14 The Regents Of The University Of California Epitopes of sars-cov-2 neutralizing antibodies
CN112426526B (zh) * 2021-01-25 2021-04-06 北京达熙生物科技有限公司 一种nk细胞的制备方法及其在治疗癌症中的应用
CN112876538B (zh) * 2021-02-04 2022-09-30 福建医科大学 靶向新生血管标记物cd105的多肽及其应用
US12162945B2 (en) 2021-03-05 2024-12-10 Immunome, Inc. EPHA2 antibodies
EP4463135A2 (en) 2022-01-10 2024-11-20 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
KR20240135852A (ko) * 2022-01-24 2024-09-12 제노백 안티바디 디스커버리 엘엘씨 항-alk1 항체 및 그의 사용 방법
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
WO2024081820A1 (en) 2022-10-13 2024-04-18 Sana Biotechnology, Inc. Viral particles targeting hematopoietic stem cells
WO2024119157A1 (en) 2022-12-02 2024-06-06 Sana Biotechnology, Inc. Lipid particles with cofusogens and methods of producing and using the same
EP4716750A1 (en) 2023-05-23 2026-04-01 Sana Biotechnology, Inc. Tandem fusogens and related lipid particles
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
WO2025045032A1 (zh) * 2023-08-29 2025-03-06 应世生物科技(南京)有限公司 一种靶向cd105的抗体或其抗原结合片段及其应用
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
WO2025184529A1 (en) 2024-03-01 2025-09-04 Sana Biotechnology, Inc. Viral particles with fusogen display and related compositions and methods
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
KR20250174161A (ko) * 2024-06-04 2025-12-12 한국과학기술연구원 엔도글린 및 메소테린 이중 항원 표적 car 및 이의 용도
TWI882851B (zh) * 2024-06-27 2025-05-01 蔡政育 基於專利技術元素整合之專利分析系統及其方法
WO2026017807A1 (en) 2024-07-18 2026-01-22 Beech Biotech Sa Compositions and uses thereof
WO2026033033A1 (en) 2024-08-07 2026-02-12 Beech Biotech Sa Compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6190660B1 (en) * 1996-05-31 2001-02-20 Health Research, Inc. Anti-endoglin monoclonal antibodies and their use in antiangiogenic therapy
US6323334B1 (en) * 1999-09-24 2001-11-27 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding a 103 gene product and uses therefor
PT2281843T (pt) * 2000-06-16 2017-01-02 Human Genome Sciences Inc Anticorpos que se ligam imunoespecificamente a blys

Similar Documents

Publication Publication Date Title
JP2012502649A5 (enExample)
JP2012525829A5 (enExample)
WO2010095031A3 (en) Humanized antibodies that bind to cd19 and their uses
JP2013198490A5 (enExample)
JP2014526898A5 (enExample)
JP2016512551A5 (enExample)
JP2014534242A5 (enExample)
JP2011526480A5 (enExample)
JP2013538057A5 (enExample)
AU2016204274A1 (en) Antibodies that bind to OX40 and their uses
JP2017052784A5 (enExample)
JP2014205674A5 (enExample)
JP2020504101A5 (enExample)
JP2013544756A5 (enExample)
JP2009225799A5 (enExample)
JP2015504306A5 (enExample)
RU2020129387A (ru) Антитела к pd-1 собак
RU2017128882A (ru) Антитела к биотину и способы их применения
JP2013517330A5 (enExample)
JP2013545455A5 (enExample)
JP2010515717A5 (enExample)
JP2011517447A5 (enExample)
RU2012142230A (ru) Антитела против csf-1r человека и их применение
JP2012531922A5 (ja) Toll様受容体2へのヒト化抗体またはその抗原結合部位
RU2012142231A (ru) Антитела против csf-1r человека и их применение