|
CH652145A5
(de)
|
1982-01-22 |
1985-10-31 |
Sandoz Ag |
Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
|
|
US4634666A
(en)
|
1984-01-06 |
1987-01-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Human-murine hybridoma fusion partner
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
EP0279582A3
(en)
|
1987-02-17 |
1989-10-18 |
Pharming B.V. |
Dna sequences to target proteins to the mammary gland for efficient secretion
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
ES2284161T3
(es)
|
1990-01-12 |
2007-11-01 |
Amgen Fremont Inc. |
Generacion de anticuerpos xenogenicos.
|
|
IE64738B1
(en)
|
1990-03-20 |
1995-09-06 |
Akzo Nv |
Stabilized gonadotropin containing preparations
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
CA2109602C
(en)
|
1990-07-10 |
2002-10-01 |
Gregory P. Winter |
Methods for producing members of specific binding pairs
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
AU8507191A
(en)
|
1990-08-29 |
1992-03-30 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5871907A
(en)
|
1991-05-15 |
1999-02-16 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US5858657A
(en)
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
ATE255131T1
(de)
|
1991-06-14 |
2003-12-15 |
Genentech Inc |
Humanisierter heregulin antikörper
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
AU3328493A
(en)
|
1991-12-17 |
1993-07-19 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
PT1621554E
(pt)
|
1992-08-21 |
2009-07-13 |
Univ Bruxelles |
Imunoglobtainas desprovidas de cadeias leves
|
|
JP3720353B2
(ja)
|
1992-12-04 |
2005-11-24 |
メディカル リサーチ カウンシル |
多価および多重特異性の結合タンパク質、それらの製造および使用
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5877218A
(en)
|
1994-01-10 |
1999-03-02 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
|
JP2000510813A
(ja)
|
1995-02-06 |
2000-08-22 |
ジェネテイックス・インスティテュート・インコーポレイテッド |
Il−12用処方
|
|
DE19539493A1
(de)
|
1995-10-24 |
1997-04-30 |
Thomae Gmbh Dr K |
Starker homologer Promotor aus Hamster
|
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
US5888809A
(en)
|
1997-05-01 |
1999-03-30 |
Icos Corporation |
Hamster EF-1α transcriptional regulatory DNA
|
|
ATE312349T1
(de)
*
|
1998-07-03 |
2005-12-15 |
Innogenetics Nv |
Differentielle diagnose von neurodegeneration
|
|
DE60045319D1
(de)
|
1999-02-05 |
2011-01-13 |
Samsung Electronics Co Ltd |
Verfahren und Vorrichtung zum Wiederauffinden von Texturbildern
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
|
EP1531864A4
(en)
|
2002-05-13 |
2006-08-23 |
Alexion Pharma Inc |
HUMANIZED ANTIBODIES TO THE VENEZOLAN HORSEMEN ENZEPHALITIS VIRUS
|
|
US9034337B2
(en)
|
2003-10-31 |
2015-05-19 |
Prothena Biosciences Limited |
Treatment and delay of outset of synucleinopathic and amyloidogenic disease
|
|
US20080014194A1
(en)
|
2003-10-31 |
2008-01-17 |
Elan Pharmaceuticals, Inc. |
Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
|
|
US8506959B2
(en)
*
|
2002-11-01 |
2013-08-13 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
TW200509968A
(en)
|
2002-11-01 |
2005-03-16 |
Elan Pharm Inc |
Prevention and treatment of synucleinopathic disease
|
|
ES2293096T3
(es)
|
2002-11-29 |
2008-03-16 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
Nuevos genes de la fosfotransferasa de neomicina y procedimiento para la seleccion de celulas recombinantes de produccion elevada.
|
|
AU2004229335C1
(en)
|
2003-04-04 |
2010-06-17 |
Genentech, Inc. |
High concentration antibody and protein formulations
|
|
US7358331B2
(en)
|
2003-05-19 |
2008-04-15 |
Elan Pharmaceuticals, Inc. |
Truncated fragments of alpha-synuclein in Lewy body disease
|
|
DE10338531A1
(de)
|
2003-08-19 |
2005-04-07 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Reklonierung von Produktionszellen
|
|
WO2005047860A2
(en)
|
2003-11-08 |
2005-05-26 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
JP2007512846A
(ja)
|
2003-12-04 |
2007-05-24 |
ゼンコー・インコーポレイテッド |
増加した宿主ストリング含有量を有する変異体タンパク質の生成方法およびその組成物
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
PL1820022T3
(pl)
|
2004-11-10 |
2009-11-30 |
Boehringer Ingelheim Pharma |
Zastosowanie analizy metodą cytometrii przepływowej w optymalizacji strategii dla banków komórek jajnika chińskiego chomika
|
|
CA2657953A1
(en)
|
2005-07-19 |
2007-01-25 |
University Of Rochester |
Alpha-synuclein antibodies and methods related thereto
|
|
WO2007021255A1
(en)
*
|
2005-08-09 |
2007-02-22 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
US8148085B2
(en)
|
2006-05-15 |
2012-04-03 |
Sea Lane Biotechnologies, Llc |
Donor specific antibody libraries
|
|
NZ574188A
(en)
|
2006-07-14 |
2012-05-25 |
Ac Immune Sa |
Humanized antibody against amyloid beta
|
|
US20080124760A1
(en)
|
2006-07-26 |
2008-05-29 |
Barbara Enenkel |
Regulatory Nucleic Acid Elements
|
|
SG178804A1
(en)
|
2007-02-23 |
2012-03-29 |
Schering Corp |
Engineered anti-il-23p19 antibodies
|
|
PL2118300T3
(pl)
|
2007-02-23 |
2015-11-30 |
Prothena Biosciences Ltd |
Zapobieganie i leczenie synukleinopatii i amyloidozy
|
|
US8147833B2
(en)
|
2007-02-23 |
2012-04-03 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
JP5467415B2
(ja)
|
2007-03-02 |
2014-04-09 |
ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト |
タンパク質製造の改良
|
|
SI2132230T1
(sl)
|
2007-03-22 |
2014-07-31 |
Genentech, Inc. |
Apoptotska protitelesa, ki veĹľejo membransko-vezan IgE
|
|
MX2009010179A
(es)
|
2007-03-22 |
2010-03-15 |
Imclone Llc |
Formulaciones estables de anticuerpo.
|
|
EP2031064A1
(de)
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Verfahren zur Steigerung von Proteintitern
|
|
ES2511844T3
(es)
|
2007-12-21 |
2014-10-23 |
F. Hoffmann-La Roche Ag |
Formulación de anticuerpo
|
|
PT2237803E
(pt)
|
2007-12-28 |
2015-10-16 |
Prothena Biosciences Ltd |
Tratamento e profilaxia da amiloidose
|
|
BRPI0906544A2
(pt)
|
2008-04-05 |
2019-01-02 |
Single Cell Tech Inc |
método de obtenção de informação a partir de células isoladas de interesse.
|
|
DK2282758T3
(en)
|
2008-04-29 |
2019-02-25 |
Bioarctic Ab |
ANTIBODIES AND VACCINES FOR USE IN THERAPEUTIC AND DIAGNOSTIC PROCEDURES FOR ALPHA-SYNUCLEIN-RELATED DISORDERS
|
|
WO2009141239A1
(en)
|
2008-05-20 |
2009-11-26 |
F. Hoffmann-La Roche Ag |
A pharmaceutical formulation comprising an antibody against ox40l, uses thereof
|
|
US20120276019A1
(en)
|
2008-07-25 |
2012-11-01 |
Diamedica Inc. |
Tissue kallikrein for the treatment of parkinson's disease
|
|
DE102008048129A1
(de)
|
2008-09-20 |
2010-04-22 |
Lfk-Lenkflugkörpersysteme Gmbh |
Flugkörper mit zumindest einem Bremsfallschirm sowie Befestigungsvorrichtung zur Befestigung eines Bremsfallschirms an einem Flugkörper
|
|
AU2009298501A1
(en)
|
2008-09-30 |
2010-04-08 |
Abbvie Inc. |
Improved antibody libraries
|
|
EP2364368B1
(en)
|
2008-11-07 |
2014-01-15 |
Sequenta, Inc. |
Methods of monitoring conditions by sequence analysis
|
|
WO2010069603A1
(en)
|
2008-12-19 |
2010-06-24 |
Neurimmune Therapeutics Ag |
Human anti-alpha-synuclein autoantibodies
|
|
NZ623910A
(en)
|
2009-07-28 |
2016-06-24 |
Shire Human Genetic Therapies |
Compositions and methods for treating gaucher disease
|
|
EP2470653A1
(en)
|
2009-08-26 |
2012-07-04 |
Research Development Foundation |
Methods for creating antibody libraries
|
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
|
EP2519537A4
(en)
|
2009-12-29 |
2013-07-10 |
Reddys Lab Ltd Dr |
CLEANING PROTEINS
|
|
EP2366714A1
(en)
|
2010-03-03 |
2011-09-21 |
Dr. Rentschler Holding GmbH & Co. KG |
Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein
|
|
TW201134488A
(en)
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
|
US9028830B2
(en)
|
2010-04-08 |
2015-05-12 |
JN Biosciences, LLC |
Antibodies to CD122
|
|
SG185428A1
(en)
|
2010-06-08 |
2012-12-28 |
Genentech Inc |
Cysteine engineered antibodies and conjugates
|
|
WO2011155607A1
(ja)
|
2010-06-11 |
2011-12-15 |
協和発酵キリン株式会社 |
抗tim-3抗体
|
|
MX343376B
(es)
|
2010-07-15 |
2016-11-03 |
Adheron Therapeutics Inc |
Anticuerpos humanizados que tienen como objetivo el dominio ec1 de cadherina-11 y composiciones y metodos relacionados.
|
|
SG10201508401TA
(en)
|
2010-10-11 |
2015-11-27 |
Abbvie Bahamas Ltd |
Processes for purification of proteins
|
|
EP2673635A4
(en)
|
2011-02-07 |
2015-08-12 |
Neotope Biosciences Ltd |
IMMUNOTHERAPY THROUGH APOE
|
|
WO2012160536A1
(en)
|
2011-05-26 |
2012-11-29 |
Dr Reddy's Laboratories Limited |
Antibody purification
|
|
US9845327B2
(en)
|
2011-06-22 |
2017-12-19 |
The General Hospital Corporation |
Treatment of proteinopathies
|
|
WO2013003680A1
(en)
|
2011-06-30 |
2013-01-03 |
Genentech, Inc. |
Anti-c-met antibody formulations
|
|
HRP20230065T1
(hr)
|
2011-10-28 |
2023-03-03 |
Prothena Biosciences Limited |
Humanizirana protutijela koja prepoznaju alfa-sinuklein
|
|
AR088579A1
(es)
|
2011-10-31 |
2014-06-18 |
Genentech Inc |
Formulaciones de anticuerpos
|
|
SG11201404321YA
(en)
|
2012-01-27 |
2014-08-28 |
Neotope Biosciences Ltd |
Humanized antibodies that recognize alpha-synuclein
|
|
RU2711552C2
(ru)
|
2012-08-29 |
2020-01-17 |
Ф. Хоффманн-Ля Рош Аг |
Шаттл для гематоэнцефалического барьера
|
|
US8925815B2
(en)
|
2012-09-05 |
2015-01-06 |
Symbol Technologies, Inc. |
Checkout system for and method of preventing a customer-operated accessory reader facing a bagging area from imaging targets on products passed through a clerk-operated workstation to the bagging area
|
|
UA118441C2
(uk)
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
US10513555B2
(en)
|
2013-07-04 |
2019-12-24 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
|
US10562973B2
(en)
|
2014-04-08 |
2020-02-18 |
Prothena Bioscience Limited |
Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
|
|
US10084674B2
(en)
|
2015-09-09 |
2018-09-25 |
International Business Machines Corporation |
Virtual desktop operation and data continuity preservation
|