|
CH652145A5
(de)
|
1982-01-22 |
1985-10-31 |
Sandoz Ag |
Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
|
|
US4634666A
(en)
|
1984-01-06 |
1987-01-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Human-murine hybridoma fusion partner
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
EP0279582A3
(en)
|
1987-02-17 |
1989-10-18 |
Pharming B.V. |
Dna sequences to target proteins to the mammary gland for efficient secretion
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
DK0710719T3
(da)
|
1990-01-12 |
2007-07-09 |
Amgen Fremont Inc |
Frembringelse af xenogene antistoffer
|
|
IE64738B1
(en)
|
1990-03-20 |
1995-09-06 |
Akzo Nv |
Stabilized gonadotropin containing preparations
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
JPH06508511A
(ja)
|
1990-07-10 |
1994-09-29 |
ケンブリッジ アンティボディー テクノロジー リミティド |
特異的な結合ペアーの構成員の製造方法
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
WO1993012227A1
(en)
|
1991-12-17 |
1993-06-24 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5858657A
(en)
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US5871907A
(en)
|
1991-05-15 |
1999-02-16 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
WO1992022653A1
(en)
|
1991-06-14 |
1992-12-23 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
DE69330523T4
(de)
|
1992-08-21 |
2012-08-23 |
Vrije Universiteit Brussel |
Immunoglobuline ohne leichte ketten
|
|
DE69329974T2
(de)
|
1992-12-04 |
2001-07-19 |
Medical Research Council, London |
Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5914349A
(en)
|
1994-01-10 |
1999-06-22 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
|
DE69620877T2
(de)
|
1995-02-06 |
2002-12-12 |
Genetics Institute, Inc. |
Arzneimittelformulierungen für il-12
|
|
DE19539493A1
(de)
|
1995-10-24 |
1997-04-30 |
Thomae Gmbh Dr K |
Starker homologer Promotor aus Hamster
|
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
US5888809A
(en)
|
1997-05-01 |
1999-03-30 |
Icos Corporation |
Hamster EF-1α transcriptional regulatory DNA
|
|
ES2255280T3
(es)
*
|
1998-07-03 |
2006-06-16 |
Innogenetics N.V. |
Diagnostico diferencial de la neurodegeneracion.
|
|
CN100405399C
(zh)
|
1999-02-05 |
2008-07-23 |
三星电子株式会社 |
图像纹理恢复方法及其装置
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
CN1671416B
(zh)
|
2001-07-12 |
2013-01-02 |
杰斐逊·富特 |
超人源化抗体
|
|
EP1531864A4
(en)
|
2002-05-13 |
2006-08-23 |
Alexion Pharma Inc |
HUMANIZED ANTIBODIES TO THE VENEZOLAN HORSEMEN ENZEPHALITIS VIRUS
|
|
US8506959B2
(en)
|
2002-11-01 |
2013-08-13 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
US9034337B2
(en)
|
2003-10-31 |
2015-05-19 |
Prothena Biosciences Limited |
Treatment and delay of outset of synucleinopathic and amyloidogenic disease
|
|
TW200509968A
(en)
|
2002-11-01 |
2005-03-16 |
Elan Pharm Inc |
Prevention and treatment of synucleinopathic disease
|
|
US20080014194A1
(en)
|
2003-10-31 |
2008-01-17 |
Elan Pharmaceuticals, Inc. |
Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
|
|
MXPA05005481A
(es)
|
2002-11-29 |
2005-07-25 |
Boehringer Ingelheim Pharma |
Nuevos genes de la fosfotransferasa de neomicina y procedimiento para la seleccion de celulas recombinantes de produccion elevada.
|
|
PT1610820E
(pt)
|
2003-04-04 |
2010-12-16 |
Novartis Ag |
Formulações de elevada concentração de anticorpos e proteínas
|
|
US7358331B2
(en)
|
2003-05-19 |
2008-04-15 |
Elan Pharmaceuticals, Inc. |
Truncated fragments of alpha-synuclein in Lewy body disease
|
|
DE10338531A1
(de)
|
2003-08-19 |
2005-04-07 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Reklonierung von Produktionszellen
|
|
WO2005047860A2
(en)
|
2003-11-08 |
2005-05-26 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
WO2005056759A2
(en)
|
2003-12-04 |
2005-06-23 |
Xencor, Inc. |
Methods of generating variant proteins with increased host string content and compositions thereof
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
CA2578400C
(en)
|
2004-11-10 |
2014-01-14 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Use of flow-cytometric analysis to optimize cell banking strategies for cho cells
|
|
US20080300204A1
(en)
|
2005-07-19 |
2008-12-04 |
University Of Rochester |
Alpha-Synuclein Antibodies and Methods Related Thereto
|
|
WO2007021255A1
(en)
*
|
2005-08-09 |
2007-02-22 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
US8148085B2
(en)
|
2006-05-15 |
2012-04-03 |
Sea Lane Biotechnologies, Llc |
Donor specific antibody libraries
|
|
WO2008011348A2
(en)
|
2006-07-14 |
2008-01-24 |
Ac Immune S.A. |
Humanized antibody against amyloid beta
|
|
US20080124760A1
(en)
|
2006-07-26 |
2008-05-29 |
Barbara Enenkel |
Regulatory Nucleic Acid Elements
|
|
CA2678863A1
(en)
|
2007-02-23 |
2008-08-28 |
Schering Corporation |
Engineered anti-il-23p19 antibodies
|
|
JP5558834B2
(ja)
*
|
2007-02-23 |
2014-07-23 |
ヤンセン アルツハイマー イミュノセラピー |
シヌクレイノパチーおよびアミロイド形成疾患（ａｍｙｌｏｉｄｏｇｅｎｉｃｄｉｓｅａｓｅ）の予防および処置
|
|
US8147833B2
(en)
|
2007-02-23 |
2012-04-03 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
BRPI0808542A2
(pt)
|
2007-03-02 |
2014-08-26 |
Boehringer Ingelheim Pharma |
Aperfeiçoamento de produção de proteína
|
|
SI2132230T1
(sl)
|
2007-03-22 |
2014-07-31 |
Genentech, Inc. |
Apoptotska protitelesa, ki veĹľejo membransko-vezan IgE
|
|
AU2008228823A1
(en)
|
2007-03-22 |
2008-09-25 |
Imclone Llc |
Stable antibody formulations
|
|
EP2031064A1
(de)
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Verfahren zur Steigerung von Proteintitern
|
|
EP2234600B1
(en)
|
2007-12-21 |
2014-08-20 |
F. Hoffmann-La Roche AG |
Antibody formulation
|
|
PT2237803E
(pt)
*
|
2007-12-28 |
2015-10-16 |
Prothena Biosciences Ltd |
Tratamento e profilaxia da amiloidose
|
|
WO2009123748A1
(en)
|
2008-04-05 |
2009-10-08 |
Single Cell Technology, Inc. |
Method of obtaining antibodies of interest and nucleotides encoding same
|
|
JP5747414B2
(ja)
|
2008-04-29 |
2015-07-15 |
バイオアークティック ニューロサイエンス アーベー |
α−シヌクレイン関連疾患についての治療および診断方法における使用のための抗体およびワクチン
|
|
WO2009141239A1
(en)
|
2008-05-20 |
2009-11-26 |
F. Hoffmann-La Roche Ag |
A pharmaceutical formulation comprising an antibody against ox40l, uses thereof
|
|
US20120276019A1
(en)
|
2008-07-25 |
2012-11-01 |
Diamedica Inc. |
Tissue kallikrein for the treatment of parkinson's disease
|
|
DE102008048129A1
(de)
|
2008-09-20 |
2010-04-22 |
Lfk-Lenkflugkörpersysteme Gmbh |
Flugkörper mit zumindest einem Bremsfallschirm sowie Befestigungsvorrichtung zur Befestigung eines Bremsfallschirms an einem Flugkörper
|
|
CN102227440A
(zh)
|
2008-09-30 |
2011-10-26 |
雅培制药有限公司 |
改良的抗体文库
|
|
WO2010053587A2
(en)
|
2008-11-07 |
2010-05-14 |
Mlc Dx Incorporated |
Methods of monitoring conditions by sequence analysis
|
|
DK2370466T3
(en)
|
2008-12-19 |
2015-08-03 |
Univ Zuerich |
Humane anti-alpha-synuclein-autoantistoffer
|
|
CN109172813B
(zh)
|
2009-07-28 |
2022-09-02 |
武田药品工业株式会社 |
用于治疗戈谢病的组合物和方法
|
|
WO2011025826A1
(en)
|
2009-08-26 |
2011-03-03 |
Research Development Foundation |
Methods for creating antibody libraries
|
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
|
WO2011090720A2
(en)
|
2009-12-29 |
2011-07-28 |
Dr. Reddy's Laboratories Ltd |
Purification of proteins
|
|
EP2366714A1
(en)
|
2010-03-03 |
2011-09-21 |
Dr. Rentschler Holding GmbH & Co. KG |
Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein
|
|
TW201134488A
(en)
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
|
CN102939305B
(zh)
|
2010-04-08 |
2016-08-17 |
Jn生物科学有限责任公司 |
对cd122的抗体
|
|
BR112012030311A2
(pt)
|
2010-06-08 |
2017-01-24 |
Genentech Inc |
anticorpo
|
|
WO2011155607A1
(ja)
|
2010-06-11 |
2011-12-15 |
協和発酵キリン株式会社 |
抗ｔｉｍ－３抗体
|
|
EP2593128B1
(en)
|
2010-07-15 |
2018-01-10 |
Adheron Therapeutics, Inc. |
Humanized antibodies targeting the ec1 domain of cadherin-11 and related compositions and methods
|
|
KR20130142128A
(ko)
|
2010-10-11 |
2013-12-27 |
애브비 인코포레이티드 |
단백질의 정제 방법
|
|
US20140050733A1
(en)
*
|
2011-02-07 |
2014-02-20 |
Dale B. Schenk |
Apoe immunotherapy
|
|
WO2012160536A1
(en)
|
2011-05-26 |
2012-11-29 |
Dr Reddy's Laboratories Limited |
Antibody purification
|
|
WO2012177997A1
(en)
|
2011-06-22 |
2012-12-27 |
The General Hospital Corporation |
Treatment of proteinopathies
|
|
CN107090038A
(zh)
|
2011-06-30 |
2017-08-25 |
霍夫曼-拉罗奇有限公司 |
抗c‑met抗体配制剂
|
|
KR101600733B1
(ko)
|
2011-10-28 |
2016-03-09 |
프로테나 바이오사이언시즈 리미티드 |
알파-시누클레인을 인식하는 인간화된 항체
|
|
PT3091029T
(pt)
|
2011-10-31 |
2023-02-03 |
Hoffmann La Roche |
Formulações de anticorpos anti-il13
|
|
JP6342333B2
(ja)
|
2012-01-27 |
2018-06-13 |
プロセナ バイオサイエンシーズ リミテッド |
α−シヌクレインを認識するヒト化抗体
|
|
CN104520329A
(zh)
|
2012-08-29 |
2015-04-15 |
霍夫曼-拉罗奇有限公司 |
血脑屏障穿梭体
|
|
US8925815B2
(en)
|
2012-09-05 |
2015-01-06 |
Symbol Technologies, Inc. |
Checkout system for and method of preventing a customer-operated accessory reader facing a bagging area from imaging targets on products passed through a clerk-operated workstation to the bagging area
|
|
UA118441C2
(uk)
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
US10513555B2
(en)
|
2013-07-04 |
2019-12-24 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
|
CA2944402A1
(en)
|
2014-04-08 |
2015-10-15 |
Prothena Biosciences Limited |
Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
|
|
US10084674B2
(en)
|
2015-09-09 |
2018-09-25 |
International Business Machines Corporation |
Virtual desktop operation and data continuity preservation
|