|
CH652145A5
(de)
|
1982-01-22 |
1985-10-31 |
Sandoz Ag |
Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
|
|
US4634666A
(en)
|
1984-01-06 |
1987-01-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Human-murine hybridoma fusion partner
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
EP0832981A1
(en)
|
1987-02-17 |
1998-04-01 |
Pharming B.V. |
DNA sequences to target proteins to the mammary gland for efficient secretion
|
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5633076A
(en)
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
|
IE64738B1
(en)
|
1990-03-20 |
1995-09-06 |
Akzo Nv |
Stabilized gonadotropin containing preparations
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
AU665190B2
(en)
|
1990-07-10 |
1995-12-21 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
KR100272077B1
(ko)
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
DE69230142T2
(de)
|
1991-05-15 |
2000-03-09 |
Cambridge Antibody Technology Ltd. |
Verfahren zur herstellung von spezifischen bindungspaargliedern
|
|
US5858657A
(en)
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
CA2124967C
(en)
|
1991-12-17 |
2008-04-08 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
EP0656946B2
(en)
|
1992-08-21 |
2010-03-31 |
Vrije Universiteit Brussel |
Immunoglobulins devoid of light chains
|
|
EP0672142B1
(en)
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5877218A
(en)
|
1994-01-10 |
1999-03-02 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
|
ATE216590T1
(de)
|
1995-02-06 |
2002-05-15 |
Genetics Inst |
Arzneimittelformulierungen für il-12
|
|
DE19539493A1
(de)
|
1995-10-24 |
1997-04-30 |
Thomae Gmbh Dr K |
Starker homologer Promotor aus Hamster
|
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
US5888809A
(en)
|
1997-05-01 |
1999-03-30 |
Icos Corporation |
Hamster EF-1α transcriptional regulatory DNA
|
|
EP1095278B1
(en)
*
|
1998-07-03 |
2005-12-07 |
Innogenetics N.V. |
Differential diagnosis of neurodegeneration
|
|
CA2361492A1
(en)
|
1999-02-05 |
2000-08-10 |
Samsung Electronics Co., Ltd. |
Image texture retrieving method and apparatus thereof
|
|
PE20020574A1
(es)
|
2000-12-06 |
2002-07-02 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido amiloideo beta
|
|
WO2004006955A1
(en)
|
2001-07-12 |
2004-01-22 |
Jefferson Foote |
Super humanized antibodies
|
|
AU2003299498A1
(en)
|
2002-05-13 |
2004-05-25 |
Alexion Pharmaceuticals, Inc. |
Humanized antibodies against the venezuelan equine encephalitis virus
|
|
TW200509968A
(en)
|
2002-11-01 |
2005-03-16 |
Elan Pharm Inc |
Prevention and treatment of synucleinopathic disease
|
|
US20080014194A1
(en)
|
2003-10-31 |
2008-01-17 |
Elan Pharmaceuticals, Inc. |
Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
|
|
US9034337B2
(en)
|
2003-10-31 |
2015-05-19 |
Prothena Biosciences Limited |
Treatment and delay of outset of synucleinopathic and amyloidogenic disease
|
|
US8506959B2
(en)
|
2002-11-01 |
2013-08-13 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
MXPA05005481A
(es)
|
2002-11-29 |
2005-07-25 |
Boehringer Ingelheim Pharma |
Nuevos genes de la fosfotransferasa de neomicina y procedimiento para la seleccion de celulas recombinantes de produccion elevada.
|
|
DK1610820T4
(da)
|
2003-04-04 |
2013-11-04 |
Genentech Inc |
Høj-koncentration antistof- og proteinformuleringer
|
|
US7358331B2
(en)
|
2003-05-19 |
2008-04-15 |
Elan Pharmaceuticals, Inc. |
Truncated fragments of alpha-synuclein in Lewy body disease
|
|
DE10338531A1
(de)
|
2003-08-19 |
2005-04-07 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Reklonierung von Produktionszellen
|
|
WO2005047860A2
(en)
*
|
2003-11-08 |
2005-05-26 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
AU2004297616B2
(en)
|
2003-12-04 |
2008-12-18 |
Xencor, Inc. |
Methods of generating variant proteins with increased host string content and compositions thereof
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
PT1820022E
(pt)
|
2004-11-10 |
2009-08-05 |
Boehringer Ingelheim Pharma |
Utilização de análise por citometria de fluxo para optimizar estratégias de conservação de bancos de células cho
|
|
US20080300204A1
(en)
|
2005-07-19 |
2008-12-04 |
University Of Rochester |
Alpha-Synuclein Antibodies and Methods Related Thereto
|
|
WO2007021255A1
(en)
*
|
2005-08-09 |
2007-02-22 |
Elan Pharmaceuticals, Inc. |
Antibodies to alpha-synuclein
|
|
US8148085B2
(en)
|
2006-05-15 |
2012-04-03 |
Sea Lane Biotechnologies, Llc |
Donor specific antibody libraries
|
|
TWI551607B
(zh)
|
2006-07-14 |
2016-10-01 |
Ａｃ免疫公司 |
人類化抗體
|
|
US20080124760A1
(en)
|
2006-07-26 |
2008-05-29 |
Barbara Enenkel |
Regulatory Nucleic Acid Elements
|
|
CA2678863A1
(en)
|
2007-02-23 |
2008-08-28 |
Schering Corporation |
Engineered anti-il-23p19 antibodies
|
|
US8147833B2
(en)
|
2007-02-23 |
2012-04-03 |
Neotope Biosciences Limited |
Prevention and treatment of synucleinopathic and amyloidogenic disease
|
|
DK3067066T3
(da)
|
2007-02-23 |
2019-05-20 |
Prothena Biosciences Ltd |
Forebyggelse og behandling af synukleinopatisk og amyloidogenisk sygdom
|
|
WO2008107388A1
(en)
|
2007-03-02 |
2008-09-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Improvement of protein production
|
|
HRP20140661T1
(hr)
|
2007-03-22 |
2014-10-10 |
Genentech, Inc. |
Apoptotiäśka protutijela anti-ige koja vežu ige spojen s membranom
|
|
UA96473C2
(ru)
|
2007-03-22 |
2011-11-10 |
Имклоун Ллк |
Жидкая стойкая композиция, которая содержит антитело imc-а12
|
|
EP2031064A1
(de)
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Verfahren zur Steigerung von Proteintitern
|
|
NZ585516A
(en)
|
2007-12-21 |
2012-07-27 |
Hoffmann La Roche |
Anti-cd20 antibody formulation
|
|
AU2008345022B2
(en)
*
|
2007-12-28 |
2014-11-06 |
Prothena Biosciences Limited |
Treatment and prophylaxis of amyloidosis
|
|
US8309317B2
(en)
|
2008-04-05 |
2012-11-13 |
Single Cell Technology, Inc. |
Method of screening single cells for the production of biologically active agents
|
|
JP5747414B2
(ja)
|
2008-04-29 |
2015-07-15 |
バイオアークティック ニューロサイエンス アーベー |
α−シヌクレイン関連疾患についての治療および診断方法における使用のための抗体およびワクチン
|
|
WO2009141239A1
(en)
|
2008-05-20 |
2009-11-26 |
F. Hoffmann-La Roche Ag |
A pharmaceutical formulation comprising an antibody against ox40l, uses thereof
|
|
US20120276019A1
(en)
|
2008-07-25 |
2012-11-01 |
Diamedica Inc. |
Tissue kallikrein for the treatment of parkinson's disease
|
|
DE102008048129A1
(de)
|
2008-09-20 |
2010-04-22 |
Lfk-Lenkflugkörpersysteme Gmbh |
Flugkörper mit zumindest einem Bremsfallschirm sowie Befestigungsvorrichtung zur Befestigung eines Bremsfallschirms an einem Flugkörper
|
|
US8404445B2
(en)
|
2008-09-30 |
2013-03-26 |
Abbvie Inc. |
Antibody libraries
|
|
GB2483810B
(en)
|
2008-11-07 |
2012-09-05 |
Sequenta Inc |
Methods for correlating clonotypes with diseases in a population
|
|
WO2010069603A1
(en)
|
2008-12-19 |
2010-06-24 |
Neurimmune Therapeutics Ag |
Human anti-alpha-synuclein autoantibodies
|
|
PL3354277T3
(pl)
|
2009-07-28 |
2021-12-13 |
Takeda Pharmaceutical Company Limited |
Kompozycje i sposoby leczenia choroby gauchera
|
|
WO2011025826A1
(en)
|
2009-08-26 |
2011-03-03 |
Research Development Foundation |
Methods for creating antibody libraries
|
|
AR078161A1
(es)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
|
|
US20130116413A1
(en)
|
2009-12-29 |
2013-05-09 |
Dr. Reddy's Laboratories, Inc. |
Purification of proteins
|
|
EP2366714A1
(en)
|
2010-03-03 |
2011-09-21 |
Dr. Rentschler Holding GmbH & Co. KG |
Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein
|
|
TW201134488A
(en)
|
2010-03-11 |
2011-10-16 |
Ucb Pharma Sa |
PD-1 antibodies
|
|
CN102939305B
(zh)
|
2010-04-08 |
2016-08-17 |
Jn生物科学有限责任公司 |
对cd122的抗体
|
|
JP2013534520A
(ja)
|
2010-06-08 |
2013-09-05 |
ジェネンテック， インコーポレイテッド |
システイン操作抗体及びコンジュゲート
|
|
HUE040213T2
(hu)
|
2010-06-11 |
2019-02-28 |
Kyowa Hakko Kirin Co Ltd |
Anti-TIM antitest
|
|
BR112013001062A2
(pt)
|
2010-07-15 |
2016-05-24 |
Synovex Corp |
anticorpos humanizados que visam o domínio ec1 de caderina-11 e composições e métodos relacionados
|
|
SG10201508401TA
(en)
|
2010-10-11 |
2015-11-27 |
Abbvie Bahamas Ltd |
Processes for purification of proteins
|
|
JP2014511174A
(ja)
*
|
2011-02-07 |
2014-05-15 |
ネオトープ バイオサイエンシーズ リミテッド |
Ａｐｏｅ免疫療法
|
|
WO2012160536A1
(en)
|
2011-05-26 |
2012-11-29 |
Dr Reddy's Laboratories Limited |
Antibody purification
|
|
US9845327B2
(en)
|
2011-06-22 |
2017-12-19 |
The General Hospital Corporation |
Treatment of proteinopathies
|
|
AU2012275233A1
(en)
|
2011-06-30 |
2013-11-28 |
Genentech, Inc. |
Anti-c-met antibody formulations
|
|
LT2771031T
(lt)
|
2011-10-28 |
2018-08-27 |
Prothena Biosciences Limited |
Humanizuoti antikūnai, kurie atpažįsta alfa sinukleiną
|
|
HK1201857A1
(en)
|
2011-10-31 |
2015-09-11 |
F. Hoffmann-La Roche Ag |
Antibody formulations
|
|
UA115439C2
(uk)
|
2012-01-27 |
2017-11-10 |
Протена Біосаєнсиз Лімітед |
Гуманізоване антитіло, яке розпізнає альфа-синуклеїн
|
|
CA2879496C
(en)
|
2012-08-29 |
2024-01-09 |
F. Hoffmann-La Roche Ag |
Blood brain barrier shuttle
|
|
US8925815B2
(en)
|
2012-09-05 |
2015-01-06 |
Symbol Technologies, Inc. |
Checkout system for and method of preventing a customer-operated accessory reader facing a bagging area from imaging targets on products passed through a clerk-operated workstation to the bagging area
|
|
UA118441C2
(uk)
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
US10513555B2
(en)
|
2013-07-04 |
2019-12-24 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
|
WO2015155694A1
(en)
|
2014-04-08 |
2015-10-15 |
Prothena Biosciences Limited |
Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
|
|
US10084674B2
(en)
|
2015-09-09 |
2018-09-25 |
International Business Machines Corporation |
Virtual desktop operation and data continuity preservation
|