JP2013528569A5 - - Google Patents

Info

Publication number

JP2013528569A5

JP2013528569A5 JP2013501861A JP2013501861A JP2013528569A5 JP 2013528569 A5 JP2013528569 A5 JP 2013528569A5 JP 2013501861 A JP2013501861 A JP 2013501861A JP 2013501861 A JP2013501861 A JP 2013501861A JP 2013528569 A5 JP2013528569 A5 JP 2013528569A5

Authority

JP

Japan

Prior art keywords

seq

cdr

nos

cdrh1

set forth

Prior art date

2011-04-01

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 101000946860 Homo sapiens T-cell surface glycoprotein CD3 epsilon chain Proteins 0.000 claims 7
• 102100035794 T-cell surface glycoprotein CD3 epsilon chain Human genes 0.000 claims 7
• 241000282577 Pan troglodytes Species 0.000 claims 6
• 125000003275 alpha amino acid group Chemical group 0.000 claims 6
• 150000007523 nucleic acids Chemical group 0.000 claims 6
• 239000008194 pharmaceutical composition Substances 0.000 claims 6
• 239000013598 vector Substances 0.000 claims 6
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
• 206010028980 Neoplasm Diseases 0.000 claims 4
• 201000011510 cancer Diseases 0.000 claims 3
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• 238000000034 method Methods 0.000 claims 3
• 229920001184 polypeptide Polymers 0.000 claims 3
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• 108090000765 processed proteins & peptides Proteins 0.000 claims 3
• 102100041003 Glutamate carboxypeptidase 2 Human genes 0.000 claims 2
• 101000892862 Homo sapiens Glutamate carboxypeptidase 2 Proteins 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 229940079593 drug Drugs 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 241000288950 Callithrix jacchus Species 0.000 claims 1
• 201000009030 Carcinoma Diseases 0.000 claims 1
• 206010060862 Prostate cancer Diseases 0.000 claims 1
• 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
• 241000288961 Saguinus imperator Species 0.000 claims 1
• 241000555745 Sciuridae Species 0.000 claims 1
• 230000009831 antigen interaction Effects 0.000 claims 1
• 210000004899 c-terminal region Anatomy 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 239000013604 expression vector Substances 0.000 claims 1
• RCRODHONKLSMIF-UHFFFAOYSA-N isosuberenol Natural products O1C(=O)C=CC2=C1C=C(OC)C(CC(O)C(C)=C)=C2 RCRODHONKLSMIF-UHFFFAOYSA-N 0.000 claims 1
• 108020004707 nucleic acids Proteins 0.000 claims 1
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• 230000001105 regulatory effect Effects 0.000 claims 1