|
CH527194A
(de)
|
1970-01-06 |
1972-08-31 |
Hoffmann La Roche |
Verfahren zur Herstellung von Isochinolin-Derivaten
|
|
US3666763A
(en)
|
1970-01-06 |
1972-05-30 |
Hoffmann La Roche |
4-phenyl isoquinolines and process for preparing same
|
|
US3947456A
(en)
*
|
1970-01-06 |
1976-03-30 |
Hoffman-La Roche Inc. |
Substituted 4-phenyl isoquinolines
|
|
JPS5223083B2
(https=)
|
1972-03-31 |
1977-06-22 |
|
|
|
JPS5223083Y2
(https=)
|
1972-06-23 |
1977-05-26 |
|
|
|
GB1504424A
(en)
*
|
1975-08-09 |
1978-03-22 |
Beecham Group Ltd |
Isoquinoline-derived aminoethers
|
|
US4340600A
(en)
*
|
1980-05-22 |
1982-07-20 |
Smithkline Corporation |
Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines
|
|
DE3333994A1
(de)
*
|
1983-09-21 |
1985-04-04 |
Troponwerke GmbH & Co KG, 5000 Köln |
Neue pyridoindolderivate, verfahren zu ihrer herstellung und ihre verwendung
|
|
US4843071A
(en)
|
1986-12-05 |
1989-06-27 |
Serotonin Industries Of Charleston |
Method and composition for treating obesity, drug abuse, and narcolepsy
|
|
CA1327795C
(en)
|
1987-08-14 |
1994-03-15 |
Jules Freedman |
Antidepressants which are aryloxy inadanamines
|
|
EP0360390A1
(en)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactam derivatives
|
|
MX18467A
(es)
|
1988-11-23 |
1993-07-01 |
Pfizer |
Agentes terapeuticos de quinuclidinas
|
|
FI895821A7
(fi)
|
1988-12-07 |
1990-06-08 |
The Wellcome Foundation Ltd |
Farmaseuttisesti aktivisia CNS-yhdisteitä
|
|
US4902710A
(en)
*
|
1988-12-14 |
1990-02-20 |
Eli Lilly And Company |
Serotonin and norepinephrine uptake inhibitors
|
|
US5114976A
(en)
*
|
1989-01-06 |
1992-05-19 |
Norden Michael J |
Method for treating certain psychiatric disorders and certain psychiatric symptoms
|
|
EP0380223A1
(en)
|
1989-01-17 |
1990-08-01 |
Konica Corporation |
Colour filter and process for producing the same
|
|
JPH02281203A
(ja)
|
1989-04-21 |
1990-11-16 |
Konica Corp |
カラーフィルター
|
|
BG49761A1
(en)
|
1989-04-24 |
1992-02-14 |
Vissh Khim T I |
4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation
|
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
|
AU6368090A
(en)
|
1989-10-03 |
1991-04-11 |
Warner-Lambert Company |
Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity
|
|
FI97540C
(fi)
|
1989-11-06 |
1997-01-10 |
Sanofi Sa |
Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
|
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
|
UA41251C2
(uk)
|
1990-01-04 |
2001-09-17 |
Пфайзер, Інк. |
Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
|
|
US5321032A
(en)
|
1990-02-15 |
1994-06-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compounds and pharmaceutical compositions thereof
|
|
US5447947A
(en)
|
1990-02-26 |
1995-09-05 |
Arc 1 |
Compositions and methods of treatment of sympathetically maintained pain
|
|
JPH072740B2
(ja)
|
1990-06-01 |
1995-01-18 |
フアイザー・インコーポレイテツド |
3―アミノ―2―アリールキヌクリジン
|
|
ATE116317T1
(de)
|
1990-07-23 |
1995-01-15 |
Pfizer |
Chinuclidinderivate.
|
|
AU687754B2
(en)
|
1990-08-31 |
1998-03-05 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
HUT68667A
(en)
|
1990-09-28 |
1995-07-28 |
Pfizer |
Fused ring analogs of nitrogen containing nonaromatic heterocycles
|
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
JPH04193867A
(ja)
|
1990-11-23 |
1992-07-13 |
Nippon Shinyaku Co Ltd |
イソキノリノール誘導体及び医薬
|
|
DK0498069T3
(da)
|
1990-12-21 |
1995-12-04 |
Fujisawa Pharmaceutical Co |
Ny anvendelse af peptidderivat
|
|
EP0566589A1
(en)
|
1991-01-10 |
1993-10-27 |
Pfizer Inc. |
N-alkyl quinuclidinium salts as substance p antagonists
|
|
EP0499313B1
(en)
|
1991-02-11 |
1997-06-11 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
ES2065175T3
(es)
|
1991-03-01 |
1995-02-01 |
Pfizer |
Derivados de 1-azabiciclo(3.2.2)nonan-3-amina.
|
|
SK284565B6
(sk)
|
1991-03-26 |
2005-06-02 |
Pfizer Inc. |
Spôsob prípravy substituovaných piperidínov
|
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
PL171921B1
(pl)
|
1991-05-22 |
1997-06-30 |
Pfizer |
Sposób wytwarzania nowych pochodnych podstawionej 3-aminochinuklidyny PL PL PL PL PL
|
|
WO1992020661A1
(en)
|
1991-05-22 |
1992-11-26 |
Merck & Co., Inc. |
N, n-diacylpiperazines
|
|
UA27776C2
(uk)
|
1991-05-31 |
2000-10-16 |
Пфайзер Інк. |
Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців
|
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
FI990419A7
(fi)
|
1991-06-20 |
1999-02-26 |
Pfizer |
Typpeä sisältävien hetrosyklisten yhdisteiden fluorialkoksibentsyyliaminojohdannaiset
|
|
TW202432B
(https=)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
JPH06509332A
(ja)
|
1991-07-05 |
1994-10-20 |
メルク シヤープ エンド ドーム リミテツド |
芳香族化合物、それらを含む医薬組成物、及び治療におけるそれらの使用
|
|
EP0536817A1
(en)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds as tachykinin antagonists
|
|
US5472978A
(en)
|
1991-07-05 |
1995-12-05 |
Merck Sharp & Dohme Ltd. |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
WO1993001165A2
(en)
|
1991-07-10 |
1993-01-21 |
Merck Sharp & Dohme Limited |
Aromatic compounds, compositions containing them and their use in therapy
|
|
US5495047A
(en)
|
1991-07-10 |
1996-02-27 |
Merck, Sharp & Dohme (Ltd.) |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
|
EP0600952B1
(en)
|
1991-08-20 |
1996-04-17 |
MERCK SHARP & DOHME LTD. |
Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
DE69231395T3
(de)
|
1991-09-20 |
2005-07-21 |
Glaxo Group Ltd., Greenford |
Neue medizinische Indikation für Tachykinin-Antagonisten
|
|
CZ59394A3
(en)
|
1991-09-26 |
1994-11-16 |
Pfizer |
Condensed tricyclic heterocycles containing nitrogen as antagonists of p substance receptor, process of their preparation, intermediates, pharmaceutical preparations in which they are comprised and use
|
|
JP2553020B2
(ja)
|
1991-11-07 |
1996-11-13 |
吉富製薬株式会社 |
キヌクリジン化合物およびその医薬用途
|
|
DK0613458T3
(da)
|
1991-11-12 |
1998-02-09 |
Pfizer |
Acykliske ethylendiaminderivater som substans P receptorantagonister
|
|
CA2083891A1
(en)
|
1991-12-03 |
1993-06-04 |
Angus Murray Macleod |
Heterocyclic compounds, compositions containing them and their use in therapy
|
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5241065A
(en)
|
1992-02-25 |
1993-08-31 |
Schering Corporation |
2,3,4,5-tetrahydro-1h-3-benzazepines having anti-psychotic activity
|
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
US5595872A
(en)
|
1992-03-06 |
1997-01-21 |
Bristol-Myers Squibb Company |
Nucleic acids encoding microsomal trigyceride transfer protein
|
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
EP0636130A1
(en)
|
1992-04-15 |
1995-02-01 |
Merck Sharp & Dohme Ltd. |
Azacyclic compounds
|
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
|
EP0641328B1
(en)
|
1992-05-18 |
2001-11-21 |
Pfizer Inc. |
Bridged aza-bicyclic derivatives as substance p antagonists
|
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
IL106142A
(en)
|
1992-06-29 |
1997-03-18 |
Merck & Co Inc |
Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them
|
|
WO1994001402A1
(en)
|
1992-07-13 |
1994-01-20 |
Merck Sharp & Dohme Limited |
Heterocyclic amide derivatives as tachykinin derivatives
|
|
EP0786522A2
(en)
|
1992-07-17 |
1997-07-30 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecules for treatment of stenotic conditions
|
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
|
ES2124318T3
(es)
|
1992-07-28 |
1999-02-01 |
Merck Sharp & Dohme |
Compuestos azaciclicos.
|
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
|
AU4718093A
(en)
|
1992-07-31 |
1994-03-03 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
|
AU4396193A
(en)
|
1992-08-04 |
1994-03-03 |
Pfizer Inc. |
3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
|
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5212185A
(en)
|
1992-08-14 |
1993-05-18 |
G. D. Searle & Co. |
Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
|
|
ATE208376T1
(de)
|
1992-08-19 |
2001-11-15 |
Pfizer |
Substituierte benzylamin-stickstoff enthaltende nichtaromatische heterocyclen
|
|
EP0585913B1
(en)
|
1992-09-04 |
1997-12-29 |
Takeda Chemical Industries, Ltd. |
Condensed heterocyclic compounds, their production and use
|
|
AU4973693A
(en)
|
1992-09-10 |
1994-03-29 |
Merck Sharp & Dohme Limited |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB2271566A
(en)
|
1992-10-14 |
1994-04-20 |
Merck & Co Inc |
HIV integrase inhibitors
|
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
AU678409B2
(en)
|
1992-10-28 |
1997-05-29 |
Merck Sharp & Dohme Limited |
4-arylmethyloxymethyl piperidines as tachykinin antagonists
|
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
|
WO1994010167A1
(en)
|
1992-10-30 |
1994-05-11 |
Merck Sharp & Dohme Limited |
Tachykinin antagonists
|
|
DK0668863T3
(da)
|
1992-11-12 |
1997-06-30 |
Pfizer |
Quinuclidinderivat som substans P-antagonist
|
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
|
JPH06153997A
(ja)
|
1992-11-27 |
1994-06-03 |
Canon Inc |
検出信号増幅による標的核酸の検出方法
|
|
CA2150123C
(en)
|
1992-12-10 |
2004-12-07 |
Harry R. Howard |
Aminomethylene substituted non-aromatic heterocycles
|
|
US5661162A
(en)
|
1992-12-14 |
1997-08-26 |
Merck Sharp & Dohme Limited |
4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperdines as tachykinin receptor antagonists
|
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
DK154192D0
(da)
*
|
1992-12-23 |
1992-12-23 |
Neurosearch As |
Heterocycliske forbindelser
|
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5466689A
(en)
|
1993-02-08 |
1995-11-14 |
Takeda Chemical Industries, Ltd. |
Morpholine derivatives and their use
|
|
ATE166867T1
(de)
|
1993-02-18 |
1998-06-15 |
Merck Sharp & Dohme |
Azacyclische verbindungen, sie enthaltende zusammensetzungen und ihre verwendung als tachykinin antagoniste
|
|
US5674889A
(en)
|
1993-02-22 |
1997-10-07 |
Merck, Sharp & Dohme, Ltd. |
Aromatic compounds, compositions containing them and their use in therapy
|
|
DE69318854T2
(de)
|
1993-03-04 |
1998-10-08 |
Pfizer |
Spiroazacyclischderivate als substanz p antagonisten
|
|
US5656642A
(en)
|
1993-04-07 |
1997-08-12 |
Otsuka Pharmaceutical Co., Ltd. |
Peripheral vasodilating agent containing piperidine derivative as active ingredient
|
|
WO1994026735A1
(en)
|
1993-05-06 |
1994-11-24 |
Merrell Dow Pharmaceuticals Inc. |
Substituted pyrrolidin-3-yl-alkyl-piperidines useful as tachykinin antagonists
|
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
|
JPH08511522A
(ja)
|
1993-06-07 |
1996-12-03 |
メルク エンド カンパニー インコーポレーテッド |
ニューロキニンアンタゴニストとしてのスピロ置換アザ環
|
|
EP0634402A1
(en)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinone derivatives, their production and use
|
|
WO1995002595A1
(en)
|
1993-07-15 |
1995-01-26 |
Pfizer Inc. |
Benzyloxyquinuclidines as substance p antagonists
|
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
|
AU7082194A
(en)
|
1993-09-17 |
1995-04-03 |
Pfizer Inc. |
Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds
|
|
WO1995007886A1
(en)
|
1993-09-17 |
1995-03-23 |
Pfizer Inc. |
3-amino-5-carboxy-substituted piperidines and 3-amino-4-carboxy-substituted pyrrolidines as tachykinin antagonists
|
|
IS4208A
(is)
|
1993-09-22 |
1995-03-23 |
Glaxo Group Limited |
3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
|
|
WO1995011880A1
(en)
|
1993-10-27 |
1995-05-04 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
|
WO1995017382A1
(en)
|
1993-12-21 |
1995-06-29 |
Eli Lilly And Company |
Non-peptide tachykinin receptor antagonists
|
|
HUT74682A
(en)
|
1993-12-29 |
1997-01-28 |
Pfizer |
Diazabicyclic neurokinin antagonists and pharmaceutical compositions containing them
|
|
IL112134A
(en)
|
1993-12-29 |
1999-12-22 |
Merck Sharp & Dohme |
Substituted morpholine derivatives their preparation and pharmaceutical compositions containing them
|
|
JPH09508376A
(ja)
|
1994-01-28 |
1997-08-26 |
メルク シヤープ エンド ドーム リミテツド |
アラルキル置換アザシクロ系の治療薬
|
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
|
IL112778A0
(en)
|
1994-03-04 |
1995-05-26 |
Merck & Co Inc |
Substituted heterocycles, their preparation and pharmaceutical compositions containing them
|
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
US5607939A
(en)
*
|
1994-04-28 |
1997-03-04 |
Takeda Chemical Industries, Ltd. |
Condensed heterocyclic compounds, their production and use
|
|
PE27997A1
(es)
|
1994-04-29 |
1997-09-20 |
Lilly Co Eli |
Antagonistas de receptores de taquicininas
|
|
WO1995030674A1
(en)
|
1994-05-05 |
1995-11-16 |
Merck Sharp & Dohme Limited |
Morpholine derivatives and their use as antagonists of tachikinins
|
|
AU690275B2
(en)
|
1994-05-07 |
1998-04-23 |
Boehringer Ingelheim International Gmbh |
Neurokinine (tachykinine) antagonists
|
|
ES2165915T3
(es)
|
1994-06-06 |
2002-04-01 |
Warner Lambert Co |
Antagonistas del receptor de la taquiquinina (nk 1).
|
|
EP0686629A3
(en)
|
1994-06-10 |
1999-02-10 |
Eli Lilly And Company |
Cyclohexyl tachykinine receptor antagonists
|
|
CA2134038C
(en)
|
1994-06-16 |
1997-06-03 |
David Taiwai Wong |
Potentiation of drug response
|
|
WO1996001819A1
(en)
|
1994-07-12 |
1996-01-25 |
Eli Lilly And Company |
Heterocyclic tachykinin receptor antagonists
|
|
CN1157610A
(zh)
|
1994-07-20 |
1997-08-20 |
比克·古尔顿·劳姆贝尔格化学公司 |
抗螺杆菌的吡啶基硫基化合物
|
|
DE4425612A1
(de)
|
1994-07-20 |
1996-04-04 |
Bayer Ag |
6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
|
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
|
US5824678A
(en)
|
1994-08-15 |
1998-10-20 |
Merck Sharp & Dohme Ltd. |
Morpholine derivatives and their use as therapeutic agents
|
|
CA2198084C
(en)
|
1994-08-25 |
2000-03-28 |
Timothy P. Burkholder |
Novel substituted piperidines useful for the treatment of allergic diseases
|
|
DE69405864T2
(de)
|
1994-08-29 |
1998-03-26 |
Akzo Nobel Nv |
Verfahren zur Herstellung von quaternären Diestern
|
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
|
HUT77318A
(hu)
|
1994-09-30 |
1998-03-30 |
Novartis Ag. |
1-Acil-4-/(alifás amino)-piperidin/-származékok, e vegyületeket tartalmazó gyógyszerkészítmények, eljárás előállításukra és alkalmazásuk
|
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
DE69534213T2
(de)
|
1994-10-25 |
2006-01-12 |
Astrazeneca Ab |
Therapeutisch wirksame Heterocyclen
|
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
|
EP0714891A1
(en)
|
1994-11-22 |
1996-06-05 |
Eli Lilly And Company |
Heterocyclic tachykinin receptor antagonists
|
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
PE38997A1
(es)
|
1994-12-13 |
1997-10-02 |
Novartis Ag |
Antagonista de taquicinina
|
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP0802912B1
(en)
|
1995-01-12 |
2004-10-13 |
Glaxo Group Limited |
Piperidine derivatives having tachykinin antagonist activity
|
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP0733632B1
(en)
|
1995-03-24 |
2003-06-04 |
Takeda Chemical Industries, Ltd. |
Cyclic compounds, their production and use as tachykinin receptor antagonists
|
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
|
JP3950170B2
(ja)
|
1995-04-13 |
2007-07-25 |
アベンティス・ファーマスーティカルズ・インコーポレイテッド |
タキキニン受容体アンタゴニスト活性を有する新規な置換されたピペラジン誘導体
|
|
NZ307625A
(en)
|
1995-05-25 |
1999-02-25 |
Fujisawa Pharmaceutical Co |
1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivatives as neurokinin receptor antagonists
|
|
US5654316A
(en)
|
1995-06-06 |
1997-08-05 |
Schering Corporation |
Piperidine derivatives as neurokinin antagonists
|
|
US5817832A
(en)
|
1995-06-22 |
1998-10-06 |
Ciba Specialty Chemicals Corporation |
Blue diketopyrrolopyrrole pigments
|
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
MX9800187A
(es)
|
1995-07-07 |
1998-05-31 |
Pfizer |
Compuestos de benzolactama substituidos como antagonistas de la substancia p.
|
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
|
AU722883B2
(en)
|
1995-10-18 |
2000-08-10 |
Merck & Co., Inc. |
Cyclopentyl tachykinin receptor antagonists
|
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1019410A1
(en)
|
1995-11-23 |
2000-07-19 |
MERCK SHARP & DOHME LTD. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
|
RU2135494C1
(ru)
|
1995-12-01 |
1999-08-27 |
Санкио Компани Лимитед |
Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина
|
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ZA9610738B
(en)
|
1995-12-22 |
1997-06-24 |
Warner Lambert Co |
Subtype selective nmda receptor ligands and the use thereof
|
|
US6025355A
(en)
|
1997-05-19 |
2000-02-15 |
Cambridge Neuroscience, Inc. |
Pharmaceutically active compounds and methods of use
|
|
WO1997036876A1
(en)
|
1996-04-03 |
1997-10-09 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
US5827875A
(en)
|
1996-05-10 |
1998-10-27 |
Bristol-Myers Squibb Company |
Inhibitors of microsomal triglyceride transfer protein and method
|
|
US5885983A
(en)
|
1996-05-10 |
1999-03-23 |
Bristol-Myers Squibb Company |
Inhibitors of microsomal triglyceride transfer protein and method
|
|
EP0906315A1
(en)
|
1996-06-21 |
1999-04-07 |
MERCK SHARP & DOHME LTD. |
Spiro-piperidine derivatives and their use as therapeutic agents
|
|
DE19638484A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
|
DE19638486A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
|
WO1998035939A1
(en)
|
1997-02-18 |
1998-08-20 |
Sanwa Kagaku Kenkyusho Co., Ltd. |
Malonic diamide derivatives and use thereof
|
|
US5907041A
(en)
|
1997-03-12 |
1999-05-25 |
Rhone-Poulenc Inc. |
Process for preparing pyrazole derivatives
|
|
JPH10292008A
(ja)
|
1997-04-21 |
1998-11-04 |
Grand Polymer:Kk |
α−オレフィンの重合方法
|
|
CA2301548C
(en)
|
1997-10-07 |
2005-05-17 |
Boehringer Ingelheim (Canada) Ltd. |
Azetidinone derivatives for the treatment of hcmv infections
|
|
CA2301967C
(en)
|
1997-10-07 |
2005-05-17 |
Boehringer Ingelheim (Canada) Ltd. |
Azetidinone derivatives for the treatment of hcmv infections
|
|
US7041702B1
(en)
|
1997-10-21 |
2006-05-09 |
Scion Pharmaceuticals, Inc. |
Pharmaceutically active compounds and methods of use
|
|
US6121261A
(en)
*
|
1997-11-19 |
2000-09-19 |
Merck & Co., Inc. |
Method for treating attention deficit disorder
|
|
US6943159B1
(en)
|
1998-02-18 |
2005-09-13 |
Neurosearch A/S |
Compounds and their use as positive AMPA receptor modulators
|
|
US6043253A
(en)
|
1998-03-03 |
2000-03-28 |
Merck & Co., Inc. |
Fused piperidine substituted arylsulfonamides as β3-agonists
|
|
WO2000014076A1
(en)
|
1998-09-04 |
2000-03-16 |
Ciba Specialty Chemicals Holding Inc. |
Process for making 2,4-dihydroxyphenyl and 2-hydroxy-4-alkoxyphenyl substituted triazine compounds
|
|
JP2000186110A
(ja)
|
1998-12-21 |
2000-07-04 |
Ube Ind Ltd |
エチレン共重合体の製造方法
|
|
WO2000041990A1
(de)
|
1999-01-12 |
2000-07-20 |
Clariant Finance (Bvi) Limited |
Benzophenone und ihre verwendung als photoinitiatoren
|
|
US6664293B2
(en)
|
1999-02-26 |
2003-12-16 |
Fujiwawa Pharmaceutical Co., Ltd. |
Amide compounds for the potentiation of cholinergic activity
|
|
US6586447B1
(en)
|
1999-04-01 |
2003-07-01 |
Pfizer Inc |
3,3-disubstituted-oxindole derivatives useful as anticancer agents
|
|
JP2001026580A
(ja)
|
1999-05-10 |
2001-01-30 |
Sumitomo Chem Co Ltd |
光学活性1−アリール−1,2,3,4−テトラヒドロイソキノリン類の製造法
|
|
US6562836B1
(en)
|
1999-05-24 |
2003-05-13 |
Queen's University Of Kingston |
Methods and compounds for inhibiting amyloid deposits
|
|
AU5567000A
(en)
|
1999-06-24 |
2001-01-09 |
Toray Industries, Inc. |
Alpha1b-adrenergic receptor antagonists
|
|
EP1237547A2
(en)
|
1999-07-09 |
2002-09-11 |
Isis Innovation Limited |
Compounds for inhibiting diseases and preparing cells for transplantation
|
|
US6340681B1
(en)
|
1999-07-16 |
2002-01-22 |
Pfizer Inc |
2-benzimidazolylamine compounds as ORL-1-receptor agonists
|
|
JP2001086110A
(ja)
|
1999-09-13 |
2001-03-30 |
Toyo Commun Equip Co Ltd |
暗号化情報のパケット通信システム
|
|
MXPA02004330A
(es)
|
1999-11-03 |
2004-07-30 |
Albany Molecular Res Inc |
Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
|
|
US7163949B1
(en)
|
1999-11-03 |
2007-01-16 |
Amr Technology, Inc. |
4-phenyl substituted tetrahydroisoquinolines and use thereof
|
|
NZ519146A
(en)
*
|
1999-11-03 |
2004-02-27 |
Albany Molecular Res Inc |
4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
|
|
EP1248869A2
(en)
|
2000-01-07 |
2002-10-16 |
Transform Pharmaceuticals, Inc. |
High-throughput formation, identification, and analysis of diverse solid-forms
|
|
AU2001262150A1
(en)
|
2000-03-23 |
2001-10-03 |
Mitsubishi Pharma Corporation |
2-(nitrogen-heterocyclic)pyrimidone derivatives
|
|
JP2003533513A
(ja)
|
2000-05-15 |
2003-11-11 |
ダーウィン・ディスカバリー・リミテッド |
Mmpおよびtnf阻害活性を有するヒドロキサム酸およびカルボン酸誘導体
|
|
US6664256B1
(en)
|
2000-07-10 |
2003-12-16 |
Kowa Co., Ltd. |
Phenylpyridazine compounds and medicines containing the same
|
|
KR100821410B1
(ko)
|
2000-07-11 |
2008-04-10 |
에이엠알 테크놀로지, 인크. |
4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
|
|
WO2002046164A1
(en)
|
2000-12-07 |
2002-06-13 |
Astrazeneca Ab |
Therapeutic compounds
|
|
US6506772B1
(en)
|
2000-12-15 |
2003-01-14 |
Hoffmann-La Roche Inc. |
Substituted [1,2,4]triazolo[1,5a]pyridine derivatives with activity as adenosine receptor ligands
|
|
US6900220B2
(en)
|
2001-01-02 |
2005-05-31 |
Syntex (U.S.A.) Llc |
Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists
|
|
US6911453B2
(en)
*
|
2001-12-05 |
2005-06-28 |
Aventis Pharma Deutschland Gmbh |
Substituted 4-phenyltetrahydroisoquinolinium, process for their preparation, their use as a medicament, and medicament containing them
|
|
US6974803B2
(en)
|
2001-12-06 |
2005-12-13 |
Pfizer Inc |
Pharmaceutical combination
|
|
US6703405B2
(en)
|
2001-12-22 |
2004-03-09 |
Aventis Pharma Deutschland Gmbh |
Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them
|
|
US20050113283A1
(en)
|
2002-01-18 |
2005-05-26 |
David Solow-Cordero |
Methods of treating conditions associated with an EDG-4 receptor
|
|
US20050261298A1
(en)
|
2002-01-18 |
2005-11-24 |
David Solow-Cordero |
Methods of treating conditions associated with an Edg-7 receptor
|
|
EP1676844A1
(en)
|
2004-12-28 |
2006-07-05 |
Laboratorios Del Dr. Esteve, S.A. |
5-HT7 receptor antagonists
|
|
CA2478909A1
(en)
|
2002-03-13 |
2003-09-25 |
Duane D. Miller |
Substituted tetrahydroisoquinoline compounds, methods of making, and their use
|
|
EP1852415B1
(en)
|
2002-07-09 |
2009-10-07 |
Lonza Ag |
Process for the preparation of N-monosubstituted beta-amino alcohols
|
|
BR0313724A
(pt)
|
2002-08-13 |
2005-06-28 |
Warner Lambert Co |
Derivados de azaisoquinolina como inibidores de metaloproteinase de matriz
|
|
BR0313727A
(pt)
|
2002-08-13 |
2005-07-12 |
Warner Lambert Co |
Derivados de isoquinolina como inibidores de metaloproteinase da matriz
|
|
CA2499523C
(en)
|
2002-09-20 |
2011-04-19 |
Medisyn Technologies, Inc. |
Therapeutic agents and corresponding treatments
|
|
WO2004035812A2
(en)
|
2002-10-16 |
2004-04-29 |
Isis Innovation Limited |
Asparaginyl hydroxylases and modulators thereof
|
|
GB0224557D0
(en)
|
2002-10-22 |
2002-11-27 |
Glaxo Group Ltd |
Novel compounds
|
|
AU2003283646A1
(en)
|
2002-12-02 |
2004-06-23 |
Pharmacia & Upjohn Company Llc |
The use of aryl- and heteroaryl-substituted tetrahydroisoquinolines in the treatment of chronic and neuropathic pain, migraine headaches, and urge, stress and mixed urinary incontinence
|
|
MXPA05005829A
(es)
|
2002-12-02 |
2005-08-29 |
Pharmacia & Upjohn Co Llc |
El uso de tetrahidroisoquinolinas 4-fenil-sustituidas en el tratamiento del dolor, dolores de cabeza migranosos e incontinencia urinaria.
|
|
DE10303254B3
(de)
|
2003-01-28 |
2004-09-23 |
Johannes-Gutenberg-Universität Mainz |
3,3-Dimethyl-8-oxoisochinoline, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und deren Verwendung
|
|
CA2513684A1
(en)
|
2003-01-31 |
2004-08-19 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
|
US7241775B2
(en)
|
2003-03-24 |
2007-07-10 |
Sanofi-Aventis Deutschland Gmbh |
Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines
|
|
WO2004096774A1
(en)
|
2003-05-01 |
2004-11-11 |
Glaxo Group Limited |
Acyl isoindoline derivatives and acyl isoquinoline derivatives as anti-viral agents
|
|
US7459460B2
(en)
|
2003-05-28 |
2008-12-02 |
Bristol-Myers Squibb Company |
Trisubstituted heteroaromatic compounds as calcium sensing receptor modulators
|
|
JP2007530417A
(ja)
|
2003-07-01 |
2007-11-01 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
細胞及び生物の寿命及びストレス応答を操作するための組成物
|
|
US7501538B2
(en)
|
2003-08-08 |
2009-03-10 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions and methods of use
|
|
US7973057B2
(en)
|
2003-09-17 |
2011-07-05 |
The United States Of America As Represented By The Department Of Health And Human Services |
Thalidomide analogs
|
|
US7491794B2
(en)
|
2003-10-14 |
2009-02-17 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
|
JP2007008816A
(ja)
|
2003-10-15 |
2007-01-18 |
Ube Ind Ltd |
新規イソキノリン誘導体
|
|
ATE386715T1
(de)
|
2003-11-25 |
2008-03-15 |
Lilly Co Eli |
Modulatoren des peroxisomproliferatoraktivierten rezeptors
|
|
US20050171027A1
(en)
|
2003-12-29 |
2005-08-04 |
President And Fellows Of Harvard College |
Compositions for treating or preventing obesity and insulin resistance disorders
|
|
EP1723134A2
(en)
|
2004-02-18 |
2006-11-22 |
Pfizer Products Incorporated |
Tetrahydroisoquinolinyl derivatives of quinazoline and isoquinoline
|
|
WO2005087235A1
(en)
|
2004-03-09 |
2005-09-22 |
National Health Research Institutes |
Pyrrolidine compounds
|
|
AP2006003763A0
(en)
|
2004-03-30 |
2006-10-31 |
Intermune Inc |
Macrocyclic compounds as inhibitors of viral replication
|
|
EP1750706B1
(en)
|
2004-06-01 |
2016-10-05 |
University Of Virginia Patent Foundation |
Dual small molecule inhibitors of cancer and angiogenesis
|
|
US20060014705A1
(en)
|
2004-06-30 |
2006-01-19 |
Howitz Konrad T |
Compositions and methods for selectively activating human sirtuins
|
|
NZ552397A
(en)
*
|
2004-07-15 |
2011-04-29 |
Amr Technology Inc |
Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
|
|
CN103251953A
(zh)
|
2004-07-19 |
2013-08-21 |
约翰·霍普金斯大学 |
供免疫抑制的flt3抑制剂
|
|
US7211585B2
(en)
|
2004-08-18 |
2007-05-01 |
Laboratorios Del Dr. Esteve, S.A. |
5-HT7 receptor antagonists
|
|
US7211584B2
(en)
|
2004-08-18 |
2007-05-01 |
Laboratorios Del Dr. Esteve, S.A. |
5-HT7 receptor ligands
|
|
DE102004046492A1
(de)
|
2004-09-23 |
2006-03-30 |
Sanofi-Aventis Deutschland Gmbh |
Substituierte 4-Phenyltetrahydroisochinoline, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, sowie sie enthaltendes Medikament
|
|
US20060111393A1
(en)
|
2004-11-22 |
2006-05-25 |
Molino Bruce F |
4-Phenyl substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
|
|
US20060111394A1
(en)
|
2004-11-22 |
2006-05-25 |
Molino Bruce F |
Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
|
|
US20060111385A1
(en)
|
2004-11-22 |
2006-05-25 |
Molino Bruce F |
Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
|
|
AU2005316337A1
(en)
*
|
2004-12-17 |
2006-06-22 |
Janssen Pharmaceutica, N.V. |
Tetrahydroisoquinoline compounds for treatment of CNS disorders
|
|
US20070060589A1
(en)
|
2004-12-21 |
2007-03-15 |
Purandare Ashok V |
Inhibitors of protein arginine methyl transferases
|
|
JP2008528510A
(ja)
|
2005-01-20 |
2008-07-31 |
サートリス ファーマシューティカルズ, インコーポレイテッド |
紅潮および/または薬物誘発性体重増加を処置するためのサーチュイン活性化化合物の使用
|
|
AU2006215608A1
(en)
|
2005-02-15 |
2006-08-24 |
Novo Nordisk A/S |
3,4-dihydro-1H-isoquinoline-2-carboxylic acid 5-aminopyridin-2-yl esters
|
|
EP2805719A1
(en)
|
2005-03-30 |
2014-11-26 |
Glaxosmithkline LLC |
Nicotinamide riboside and analogues thereof
|
|
DE102005025625A1
(de)
|
2005-06-01 |
2006-12-07 |
Friedrich-Schiller-Universität Jena |
Neue hochaffine Dopaminantagonisten zur Behandlung der Schizophrenie und Verfahren zu ihrer Herstellung
|
|
KR101594898B1
(ko)
|
2005-07-15 |
2016-02-18 |
알바니 몰레큘라 리써치, 인크. |
아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
|
|
US7425633B2
(en)
|
2005-08-26 |
2008-09-16 |
National Health Research Institutes |
Pyrrolidine compounds
|
|
EP1924546A1
(en)
|
2005-09-14 |
2008-05-28 |
Amgen, Inc |
Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders
|
|
US20080255149A1
(en)
|
2005-09-27 |
2008-10-16 |
Novartis Ag |
Carboxyamine Compounds and Methods of Use Thereof
|
|
WO2007048788A1
(en)
|
2005-10-26 |
2007-05-03 |
Laboratoires Serono S.A. |
Sulfonamide derivatives and use thereof for the modulation of metalloproteinases
|
|
JP4955009B2
(ja)
|
2005-11-11 |
2012-06-20 |
エフ.ホフマン−ラ ロシュ アーゲー |
凝固因子Xaの阻害剤としての炭素環式縮合環アミン
|
|
WO2007098608A1
(en)
|
2006-03-02 |
2007-09-07 |
Chao-Jun Li |
Chiral ligands, their preparation and uses thereof in assymetric reactions
|
|
EP2001866A2
(en)
|
2006-03-29 |
2008-12-17 |
Novartis AG |
Organic compounds
|
|
JP5223083B2
(ja)
|
2006-06-21 |
2013-06-26 |
国立大学法人京都大学 |
血管新生抑制剤
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
WO2008005368A2
(en)
|
2006-06-30 |
2008-01-10 |
Abbott Laboratories |
Piperazines as p2x7 antagonists
|
|
ATE459352T1
(de)
|
2006-07-04 |
2010-03-15 |
Janssen Pharmaceutica Nv |
Benzimidazol-cannabinoid-agonisten mit einer substituierten heterocyclischen gruppe
|
|
ES2576477T3
(es)
|
2006-08-07 |
2016-07-07 |
Janssen Pharmaceutica Nv |
Proceso para la preparación de derivados de 1,2,3,4-tetrahidroisoquinolina sustituidos
|
|
SG174095A1
(en)
|
2006-08-23 |
2011-09-29 |
Valeant Pharmaceuticals Int |
Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
|
|
US8993593B2
(en)
|
2006-08-23 |
2015-03-31 |
Valeant Pharmaceuticals International |
N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
|
|
DE102006046922B3
(de)
|
2006-09-27 |
2007-11-15 |
Julius-Maximilians-Universität Würzburg |
Biofilm-hemmende Wirkung sowie anti-infektive Aktivität N,C-verknüpfter Arylisochinoline, deren pharmazeutischen Zusammensetzung und deren Verwendung
|
|
WO2008058126A2
(en)
|
2006-11-06 |
2008-05-15 |
Supergen, Inc. |
Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
|
|
CA2679735A1
(en)
|
2007-03-01 |
2008-09-12 |
Janssen Pharmaceutica N.V. |
Tetrahydroisoquinoline compounds as modulators of the histamine h3 receptor
|
|
US7321064B1
(en)
|
2007-03-08 |
2008-01-22 |
Cedarburg Pharmaceuticals, Inc. |
Preparation of amides of retinoic acid via mixed anhydride and mixed carbonate intermediates
|
|
NZ580802A
(en)
|
2007-05-10 |
2012-09-28 |
Albany Molecular Res Inc |
Aryloxy-and heteroaryloxy-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
|
|
JP2010526825A
(ja)
|
2007-05-10 |
2010-08-05 |
エーエムアール テクノロジー インコーポレイテッド |
アリール置換およびヘテロアリール置換テトラヒドロベンゾ−1,4−ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
|
|
US7846930B2
(en)
*
|
2007-05-18 |
2010-12-07 |
Janssen Pharmaceutica Nv |
Diaryl-substituted tetrahydroisoquinolines as histamine H3 receptor and serotonin transporter modulators
|
|
EP2167083B1
(en)
|
2007-06-06 |
2015-10-28 |
Euthymics Bioscience, Inc. |
1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
|
|
US9156812B2
(en)
|
2008-06-04 |
2015-10-13 |
Bristol-Myers Squibb Company |
Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
|
|
AR071997A1
(es)
|
2008-06-04 |
2010-07-28 |
Bristol Myers Squibb Co |
Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
|
|
WO2009155565A1
(en)
|
2008-06-20 |
2009-12-23 |
Genentech, Inc. |
Triazolopyridine jak inhibitor compounds and methods
|
|
TWI453207B
(zh)
|
2008-09-08 |
2014-09-21 |
Signal Pharm Llc |
胺基三唑并吡啶,其組合物及使用其之治療方法
|
|
AU2010247763B2
(en)
|
2009-05-12 |
2015-12-24 |
Albany Molecular Research, Inc. |
7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
|
|
AU2010247735B2
(en)
|
2009-05-12 |
2015-07-16 |
Albany Molecular Research, Inc. |
Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof
|
|
WO2010132437A1
(en)
|
2009-05-12 |
2010-11-18 |
Albany Molecular Research, Inc. |
Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof
|
|
US8691810B2
(en)
|
2010-05-12 |
2014-04-08 |
Abbvie Inc. |
Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases
|
|
WO2012024397A2
(en)
|
2010-08-17 |
2012-02-23 |
Albany Molecular Research, Inc. |
2,5-methano-and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
|
|
WO2014159501A2
(en)
|
2013-03-14 |
2014-10-02 |
Bristol-Myers Squibb Company |
Processes for preparing tetrahydroisoquinolines
|