UA27776C2 - Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців - Google Patents
Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавцівInfo
- Publication number
- UA27776C2 UA27776C2 UA93004096A UA93004096A UA27776C2 UA 27776 C2 UA27776 C2 UA 27776C2 UA 93004096 A UA93004096 A UA 93004096A UA 93004096 A UA93004096 A UA 93004096A UA 27776 C2 UA27776 C2 UA 27776C2
- Authority
- UA
- Ukraine
- Prior art keywords
- substance
- mammals
- receptor antagonists
- saults
- pharmaceutically acceptable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Винахід належить до нових похідних хінуклідину, фармацевтичних композицій, що містять такі сполуки, і до застосування таких сполук для лікування й попередження запальних розладів і розладів центральної нервової системи. Фармацевтично активні сполуки даного винаходу є антагоністами рецепторної речовини P. Цей винахід належить також до нових проміжних сполук, що використовуються для синтезу таких антагоністів речовини Р.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70840491A | 1991-05-31 | 1991-05-31 | |
PCT/US1992/003317 WO1992021677A1 (en) | 1991-05-31 | 1992-04-28 | bibNUCLIDINE DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
UA27776C2 true UA27776C2 (uk) | 2000-10-16 |
Family
ID=24845673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA93004096A UA27776C2 (uk) | 1991-05-31 | 1992-04-28 | Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців |
Country Status (41)
Country | Link |
---|---|
US (3) | US5807867A (uk) |
EP (1) | EP0587723B1 (uk) |
JP (2) | JPH0733386B2 (uk) |
KR (1) | KR100214905B1 (uk) |
CN (1) | CN1048492C (uk) |
AP (1) | AP299A (uk) |
AT (1) | ATE135006T1 (uk) |
AU (1) | AU657552B2 (uk) |
BG (1) | BG61694B1 (uk) |
BR (1) | BR9206073A (uk) |
CA (1) | CA2102179C (uk) |
CZ (1) | CZ281403B6 (uk) |
DE (4) | DE122006000066I2 (uk) |
DK (1) | DK0587723T3 (uk) |
EG (1) | EG19944A (uk) |
ES (1) | ES2084361T3 (uk) |
FI (1) | FI114475B (uk) |
GR (1) | GR3019687T3 (uk) |
GT (1) | GT199200028A (uk) |
HU (1) | HU217548B (uk) |
IE (1) | IE72473B1 (uk) |
IL (1) | IL102008A (uk) |
IS (1) | IS1611B (uk) |
LU (1) | LU91293I2 (uk) |
MA (1) | MA22539A1 (uk) |
MX (1) | MX9202554A (uk) |
NL (1) | NL300250I2 (uk) |
NO (2) | NO302701B1 (uk) |
NZ (2) | NZ242956A (uk) |
OA (1) | OA09867A (uk) |
PL (1) | PL171379B1 (uk) |
PT (1) | PT100546B (uk) |
RO (1) | RO110499B1 (uk) |
RU (1) | RU2103269C1 (uk) |
SK (1) | SK390692A3 (uk) |
TW (1) | TW204349B (uk) |
UA (1) | UA27776C2 (uk) |
UY (1) | UY23422A1 (uk) |
WO (1) | WO1992021677A1 (uk) |
YU (1) | YU48995B (uk) |
ZA (1) | ZA923942B (uk) |
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GB9218334D0 (en) * | 1992-08-28 | 1992-10-14 | Ici Plc | Heterocyclic compounds |
US5340826A (en) * | 1993-02-04 | 1994-08-23 | Pfizer Inc. | Pharmaceutical agents for treatment of urinary incontinence |
US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
EP0655246A1 (en) * | 1993-11-30 | 1995-05-31 | Pfizer Inc. | Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria |
US5576317A (en) * | 1994-12-09 | 1996-11-19 | Pfizer Inc. | NK-1 receptor antagonists and 5HT3 receptor antagonists for the treatment of emesis |
ES2147889T3 (es) * | 1996-01-19 | 2000-10-01 | Lonza Ag | Metodo para preparar 3-hidroxiquinuclidinol opticamente activo. |
US5990125A (en) * | 1996-01-19 | 1999-11-23 | Pfizer Inc. | NK-1 receptor antagonists for the treatment of cancer |
-
1992
- 1992-04-28 KR KR1019930703649A patent/KR100214905B1/ko not_active IP Right Cessation
- 1992-04-28 WO PCT/US1992/003317 patent/WO1992021677A1/en active IP Right Grant
- 1992-04-28 CZ CS923906A patent/CZ281403B6/cs not_active IP Right Cessation
- 1992-04-28 BR BR9206073A patent/BR9206073A/pt not_active Application Discontinuation
- 1992-04-28 DE DE200612000066 patent/DE122006000066I2/de active Active
- 1992-04-28 DE DE1992608877 patent/DE122006000066I1/de active Pending
- 1992-04-28 PL PL92301472A patent/PL171379B1/pl unknown
- 1992-04-28 RU RU93058555A patent/RU2103269C1/ru active Protection Beyond IP Right Term
- 1992-04-28 HU HU9303393A patent/HU217548B/hu active Protection Beyond IP Right Term
- 1992-04-28 DK DK92912601.9T patent/DK0587723T3/da active
- 1992-04-28 CA CA002102179A patent/CA2102179C/en not_active Expired - Lifetime
- 1992-04-28 AU AU19901/92A patent/AU657552B2/en not_active Expired
- 1992-04-28 US US08/211,120 patent/US5807867A/en not_active Expired - Lifetime
- 1992-04-28 JP JP5500353A patent/JPH0733386B2/ja not_active Expired - Lifetime
- 1992-04-28 SK SK3906-92A patent/SK390692A3/sk not_active IP Right Cessation
- 1992-04-28 DE DE9290063U patent/DE9290063U1/de not_active Expired - Lifetime
- 1992-04-28 DE DE69208877T patent/DE69208877T2/de not_active Expired - Lifetime
- 1992-04-28 AT AT92912601T patent/ATE135006T1/de active
- 1992-04-28 RO RO93-01581A patent/RO110499B1/ro unknown
- 1992-04-28 UA UA93004096A patent/UA27776C2/uk unknown
- 1992-04-28 ES ES92912601T patent/ES2084361T3/es not_active Expired - Lifetime
- 1992-04-28 EP EP92912601A patent/EP0587723B1/en not_active Expired - Lifetime
- 1992-05-05 TW TW081103509A patent/TW204349B/zh not_active IP Right Cessation
- 1992-05-11 AP APAP/P/1992/000384A patent/AP299A/en active
- 1992-05-26 UY UY23422A patent/UY23422A1/es not_active IP Right Cessation
- 1992-05-26 IL IL10200892A patent/IL102008A/en active Protection Beyond IP Right Term
- 1992-05-29 MX MX9202554A patent/MX9202554A/es unknown
- 1992-05-29 ZA ZA923942A patent/ZA923942B/xx unknown
- 1992-05-29 NZ NZ242956A patent/NZ242956A/en not_active IP Right Cessation
- 1992-05-29 MA MA22826A patent/MA22539A1/fr unknown
- 1992-05-29 PT PT100546A patent/PT100546B/pt not_active IP Right Cessation
- 1992-05-29 NZ NZ270673A patent/NZ270673A/en not_active IP Right Cessation
- 1992-05-29 GT GT199200028A patent/GT199200028A/es unknown
- 1992-05-29 IS IS3871A patent/IS1611B/is unknown
- 1992-05-29 YU YU56492A patent/YU48995B/sh unknown
- 1992-05-30 CN CN92104129A patent/CN1048492C/zh not_active Expired - Lifetime
- 1992-05-30 EG EG28492A patent/EG19944A/xx active
- 1992-07-01 IE IE921729A patent/IE72473B1/en not_active IP Right Cessation
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1993
- 1993-11-26 BG BG98248A patent/BG61694B1/bg unknown
- 1993-11-29 FI FI935297A patent/FI114475B/fi not_active IP Right Cessation
- 1993-11-29 NO NO934312A patent/NO302701B1/no not_active IP Right Cessation
- 1993-11-30 OA OA60442A patent/OA09867A/en unknown
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1994
- 1994-10-05 JP JP6241456A patent/JP2645225B2/ja not_active Expired - Lifetime
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1995
- 1995-01-24 US US08/377,552 patent/US6222038B1/en not_active Expired - Lifetime
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1996
- 1996-04-19 GR GR960401066T patent/GR3019687T3/el unknown
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1997
- 1997-04-30 US US08/846,909 patent/US5939433A/en not_active Expired - Lifetime
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2006
- 2006-12-06 NL NL300250C patent/NL300250I2/nl unknown
- 2006-12-06 LU LU91293C patent/LU91293I2/fr unknown
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2007
- 2007-03-09 NO NO2007003C patent/NO2007003I2/no unknown
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