BG49761A1 - 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation - Google Patents

4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation

Info

Publication number
BG49761A1
BG49761A1 BG8822089A BG8822089A BG49761A1 BG 49761 A1 BG49761 A1 BG 49761A1 BG 8822089 A BG8822089 A BG 8822089A BG 8822089 A BG8822089 A BG 8822089A BG 49761 A1 BG49761 A1 BG 49761A1
Authority
BG
Bulgaria
Prior art keywords
tetrahydroisohinolines
chalophenyl
methyl
preparation
Prior art date
Application number
BG8822089A
Inventor
Nedjalka S Ivanova
Donka M Mondeshka
Chavdar B Ivanov
Ivanka G Angelova
Stefan E Bojadzhiev
Chonka N Tancheva
Spaska A Terzijska
Mariana R Tosheva
Vladimir A Parashikov
Vladimir D Paskov
Veselin A Velkov
Original Assignee
Vissh Khim T I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vissh Khim T I filed Critical Vissh Khim T I
Priority to BG8822089A priority Critical patent/BG49761A1/en
Priority to EP90107538A priority patent/EP0400319A1/en
Priority to CA 2015114 priority patent/CA2015114A1/en
Priority to AU53810/90A priority patent/AU5381090A/en
Priority to PL28491190A priority patent/PL284911A1/en
Publication of BG49761A1 publication Critical patent/BG49761A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG8822089A 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation BG49761A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BG8822089A BG49761A1 (en) 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation
EP90107538A EP0400319A1 (en) 1989-04-24 1990-04-20 4-(4'-Halophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolines and process for their preparation
CA 2015114 CA2015114A1 (en) 1989-04-24 1990-04-23 4-/4'-halophenyl/-2-methyl-1,2,3,4-tetrahydroisoquinolines and a method for their preparation
AU53810/90A AU5381090A (en) 1989-04-24 1990-04-24 4-(-4'-halophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinolines and a method for their preparation
PL28491190A PL284911A1 (en) 1989-04-24 1990-04-24 Method of obtaining novel 4-/4'-halogenophenyl/-2-methyl-1,2,3,4-tetrahydroisoquinolines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG8822089A BG49761A1 (en) 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation

Publications (1)

Publication Number Publication Date
BG49761A1 true BG49761A1 (en) 1992-02-14

Family

ID=3921819

Family Applications (1)

Application Number Title Priority Date Filing Date
BG8822089A BG49761A1 (en) 1989-04-24 1989-04-24 4- (4'- chalophenyl)- 2- methyl- 1, 2, 3, 4- tetrahydroisohinolines and method for its preparation

Country Status (5)

Country Link
EP (1) EP0400319A1 (en)
AU (1) AU5381090A (en)
BG (1) BG49761A1 (en)
CA (1) CA2015114A1 (en)
PL (1) PL284911A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2304984T3 (en) * 1999-11-03 2008-11-01 Amr Technology, Inc. TETRA-HYDROISOQUINOLINAS OF ARILICA AND HETEROARILICA SUBSTITUTION AND ITS USE TO BLOCK THE RECOVERY OF NOREPINEFRINE, DOPAMINE AND SEROTONINE.
EP1246805A1 (en) * 1999-11-03 2002-10-09 Albany Molecular Research, Inc. 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
NZ523456A (en) 2000-07-11 2004-11-26 Albany Molecular Res Inc Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
KR101412339B1 (en) 2004-07-15 2014-06-25 알바니 몰레큘라 리써치, 인크. Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
CN101128432A (en) * 2004-12-17 2008-02-20 詹森药业有限公司 Tetrahydroisoquinoline compounds for treatment of cns disorders
KR20080044840A (en) 2005-07-15 2008-05-21 에이엠알 테크놀로지, 인크. Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (en) 2008-06-04 2010-07-28 Bristol Myers Squibb Co CRYSTAL FORM OF 6 - ((4S) -2-METHYL-4- (2-NAFTIL) -1,2,3,4-TETRAHYDROISOQUINOLIN-7-IL) PIRIDAZIN-3-AMINA
ES2528404T3 (en) 2009-05-12 2015-02-10 Bristol-Myers Squibb Company Crystal forms of (S) -7 - ([1,2,4] triazol [1,5-a] pyridin-6-yl) -4- (3,4-dichlorophenyl) -1,2,3,4- tetrahydroisoquinoline and its uses
CN102595902B (en) 2009-05-12 2015-04-29 阿尔巴尼分子研究公司 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
ES2446971T3 (en) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahydroisoquinolines substituted with aryl, heteroaryl, and heterocycle and their use

Also Published As

Publication number Publication date
AU5381090A (en) 1990-10-25
EP0400319A1 (en) 1990-12-05
PL284911A1 (en) 1991-11-04
CA2015114A1 (en) 1990-10-24

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