IL202354A - A method for sonication of fibroin through sonication - Google Patents

A method for sonication of fibroin through sonication

Info

Publication number
IL202354A
IL202354A IL202354A IL20235409A IL202354A IL 202354 A IL202354 A IL 202354A IL 202354 A IL202354 A IL 202354A IL 20235409 A IL20235409 A IL 20235409A IL 202354 A IL202354 A IL 202354A
Authority
IL
Israel
Prior art keywords
sonication
silk fibroin
fibroin gelation
gelation
silk
Prior art date
Application number
IL202354A
Other languages
English (en)
Hebrew (he)
Other versions
IL202354A0 (en
Original Assignee
Tufts College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tufts College filed Critical Tufts College
Publication of IL202354A0 publication Critical patent/IL202354A0/en
Publication of IL202354A publication Critical patent/IL202354A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43586—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from silkworms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
IL202354A 2007-05-29 2009-11-26 A method for sonication of fibroin through sonication IL202354A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94055407P 2007-05-29 2007-05-29
PCT/US2008/065076 WO2008150861A1 (en) 2007-05-29 2008-05-29 Method for silk fibroin gelation using sonication

Publications (2)

Publication Number Publication Date
IL202354A0 IL202354A0 (en) 2010-06-30
IL202354A true IL202354A (en) 2016-11-30

Family

ID=40094093

Family Applications (1)

Application Number Title Priority Date Filing Date
IL202354A IL202354A (en) 2007-05-29 2009-11-26 A method for sonication of fibroin through sonication

Country Status (20)

Country Link
US (4) US8187616B2 (https=)
EP (1) EP2211876B1 (https=)
JP (2) JP2010529230A (https=)
KR (2) KR20100029217A (https=)
CN (2) CN101772348B (https=)
AU (1) AU2008260156B2 (https=)
BR (1) BRPI0813312A2 (https=)
CA (1) CA2688431C (https=)
CY (1) CY1116090T1 (https=)
DK (1) DK2211876T3 (https=)
EA (1) EA019118B1 (https=)
ES (1) ES2527125T3 (https=)
HK (1) HK1201470A1 (https=)
HR (1) HRP20141265T1 (https=)
IL (1) IL202354A (https=)
MX (1) MX2009012978A (https=)
PL (1) PL2211876T3 (https=)
PT (1) PT2211876E (https=)
SI (1) SI2211876T1 (https=)
WO (1) WO2008150861A1 (https=)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6092337A (ja) * 1983-10-26 1985-05-23 Sekisui Plastics Co Ltd 発泡フエノ−ル樹脂成形物の製造方法
EP2662211A1 (en) * 2002-06-24 2013-11-13 Tufts University Silk biomaterials and methods of use thereof
WO2004062697A2 (en) 2003-01-07 2004-07-29 Tufts University Silk fibroin materials and use thereof
CA2562415C (en) 2003-04-10 2015-10-27 Tufts University Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
CN102683391B (zh) 2004-06-04 2015-11-18 伊利诺伊大学评议会 用于制造并组装可印刷半导体元件的方法和设备
US8529835B2 (en) 2006-11-03 2013-09-10 Tufts University Biopolymer sensor and method of manufacturing the same
JP2010509645A (ja) 2006-11-03 2010-03-25 トラスティーズ オブ タフツ カレッジ ナノパターンが形成されたバイオポリマー光学デバイスおよびその製造方法
US8195021B2 (en) 2006-11-03 2012-06-05 Tufts University/Trustees Of Tufts College Biopolymer optical waveguide and method of manufacturing the same
WO2008106485A2 (en) 2007-02-27 2008-09-04 Trustees Of Tufts College Tissue-engineered silk organs
KR20100029217A (ko) 2007-05-29 2010-03-16 트러스티즈 오브 터프츠 칼리지 음파 처리를 이용한 실크 피브로인 겔화 방법
CA2713251A1 (en) * 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
GB0807868D0 (en) * 2008-04-30 2008-06-04 Knight David P Cartilage repair material and a method for the preparation thereof
MX341351B (es) * 2008-05-15 2016-08-17 Tufts College Liberacion de adenosina basada en polimero de seda: potencial terapeutico para la epilepsia.
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
US9289132B2 (en) 2008-10-07 2016-03-22 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
US20110223153A1 (en) 2008-10-09 2011-09-15 Trustees Of Tufts College Modified silk films containing glycerol
JP5909362B2 (ja) * 2009-03-04 2016-04-26 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 抗生物質送達のための絹フィブロインシステム
WO2011005381A2 (en) 2009-06-01 2011-01-13 Trustees Of Tufts College Vortex-induced silk fibroin gelation for encapsulation and delivery
WO2011008842A2 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
ES2426478T3 (es) * 2009-07-31 2013-10-23 Council Of Scientific & Industrial Research Gelificación acelerada de fibroína regenerada
CA2775706A1 (en) 2009-09-28 2011-03-31 Trustees Of Tufts College Drawn silk egel fibers and methods of making same
EP2483199B1 (en) 2009-09-29 2017-04-26 Trustees Of Tufts College Silk nanospheres and microspheres and methods of making same
US9723122B2 (en) 2009-10-01 2017-08-01 Mc10, Inc. Protective cases with integrated electronics
US8666471B2 (en) 2010-03-17 2014-03-04 The Board Of Trustees Of The University Of Illinois Implantable biomedical devices on bioresorbable substrates
US10918298B2 (en) 2009-12-16 2021-02-16 The Board Of Trustees Of The University Of Illinois High-speed, high-resolution electrophysiology in-vivo using conformal electronics
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US9936574B2 (en) 2009-12-16 2018-04-03 The Board Of Trustees Of The University Of Illinois Waterproof stretchable optoelectronics
US9603971B2 (en) 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
JP2013533754A (ja) 2010-04-12 2013-08-29 タフツ・ユニバーシティ 絹電子部品
EP2611473A4 (en) 2010-09-01 2014-08-13 Tufts College SILK FIBROIN AND POLYETHYLENE GLYCOL BIOMATERIALS
US9517357B2 (en) 2010-09-03 2016-12-13 Tufts University Plasmonic nanoparticle-doped silk materials
US9761789B2 (en) 2010-09-27 2017-09-12 Tufts University Silk-based piezoelectric materials
WO2012054582A2 (en) 2010-10-19 2012-04-26 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
JP2012171124A (ja) * 2011-02-18 2012-09-10 Sekisui Chem Co Ltd 製管用部材、及び既設管の更生方法
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
AU2012245198B2 (en) 2011-04-21 2017-07-13 Trustees Of Tufts College Compositions and methods for stabilization of active agents
WO2012158709A1 (en) 2011-05-16 2012-11-22 The Board Of Trustees Of The University Of Illinois Thermally managed led arrays assembled by printing
US9159635B2 (en) 2011-05-27 2015-10-13 Mc10, Inc. Flexible electronic structure
US8934965B2 (en) 2011-06-03 2015-01-13 The Board Of Trustees Of The University Of Illinois Conformable actively multiplexed high-density surface electrode array for brain interfacing
WO2013103424A2 (en) * 2011-10-11 2013-07-11 Tufts University Silk-based multifunctional biomedical platform
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
CA2890366A1 (en) 2011-11-09 2013-05-16 Trustees Of Tufts College Injectable silk fibroin particles and uses thereof
ES2791769T3 (es) 2011-11-09 2020-11-05 Tufts College Espumas de fibroína de seda inyectables y usos de la misma
CN108389893A (zh) 2011-12-01 2018-08-10 伊利诺伊大学评议会 经设计以经历可编程转变的瞬态器件
WO2013130156A2 (en) 2011-12-05 2013-09-06 Tufts University Signal enhancement by silk photonic crystals
BR112014016154A8 (pt) 2011-12-29 2017-07-04 Tufts College funcionalização de biomateriais para controlar respostas à regeneração e inflamação
US10912862B2 (en) 2012-02-06 2021-02-09 Children's Medical Center Corporation Multi-layer biomaterial for tissue regeneration and wound healing
US20150037422A1 (en) * 2012-02-22 2015-02-05 Trustees Of Tufts College Compositions and methods for ocular delivery of a therapeutic agent
CA2867464A1 (en) 2012-03-20 2013-09-26 Trustees Of Tufts College Silk reservoirs for drug delivery
EP2830492B1 (en) 2012-03-30 2021-05-19 The Board of Trustees of the University of Illinois Appendage mountable electronic devices conformable to surfaces and method of making the same
US9925301B2 (en) 2012-04-06 2018-03-27 Trustees Of Tufts College Methods of producing and using silk microfibers
EP2836236B1 (en) * 2012-04-13 2019-01-02 Trustees Of Tufts College Methods and compositions for preparing a silk microsphere
WO2013163407A1 (en) 2012-04-25 2013-10-31 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
JP2015530361A (ja) * 2012-07-13 2015-10-15 タフツ・ユニバーシティ 絹フィブロイン生体材料における非混和性の相の封入
US10034945B2 (en) 2012-07-13 2018-07-31 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
EP2712955A1 (en) * 2012-09-27 2014-04-02 Ludwig Boltzmann Gesellschaft GmbH Product made of silk
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
CN104837500A (zh) * 2012-10-11 2015-08-12 塔夫茨大学 用于持续递送胰高血糖素样肽(glp-1)受体激动剂治疗剂的组合物和方法
WO2014085725A1 (en) 2012-11-27 2014-06-05 Tufts University Biopolymer-based inks and use thereof
WO2014145002A2 (en) 2013-03-15 2014-09-18 Kluge Jonathan A Low molecular weight silk compositions and stabilizing silk compositions
WO2014197093A2 (en) 2013-03-15 2014-12-11 Tufts University All water-based nanopatterning
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US10464361B2 (en) 2013-03-15 2019-11-05 Tufts University Silk water lithography
WO2014176458A2 (en) 2013-04-24 2014-10-30 Trustees Of Tufts College Bioresorbable biopolymer anastomosis devices
WO2015023798A1 (en) * 2013-08-13 2015-02-19 Lewis, Randolph, V. Synthetic spider silk protein compositions and methods
WO2015048527A1 (en) 2013-09-27 2015-04-02 Tufts University Optically transparent silk hydrogels
CA2925820C (en) 2013-09-30 2021-11-30 Silk Therapeutics, Inc. Silk protein fragment compositions and articles manufactured therefrom
WO2015054125A1 (en) 2013-10-08 2015-04-16 Trustees Of Tufts College Tunable covalently crosslinked hydrogels and methods of making the same
US10513802B2 (en) 2013-11-08 2019-12-24 Tufts University Peptide-based nanofibrillar materials
ES2781114T3 (es) * 2014-08-20 2020-08-28 Silk Tech Ltd Composición proteica derivada de fibroína
EA035551B1 (ru) 2014-12-02 2020-07-06 Силк Терапьютикс, Инк. Изделие
EP3268381B1 (en) 2015-03-12 2022-03-02 Tufts University Shape memory silk materials
CN107851208B (zh) 2015-06-01 2021-09-10 伊利诺伊大学评议会 具有无线供电和近场通信能力的小型化电子系统
WO2016196673A1 (en) 2015-06-01 2016-12-08 The Board Of Trustees Of The University Of Illinois Alternative approach to uv sensing
AU2016294611B2 (en) 2015-07-14 2022-08-11 Evolved By Nature, Inc. Silk performance apparel and products and methods of preparing the same
US20200054792A1 (en) 2015-07-28 2020-02-20 Trustees Of Tufts College Polypeptide monoliths
US10925543B2 (en) 2015-11-11 2021-02-23 The Board Of Trustees Of The University Of Illinois Bioresorbable silicon electronics for transient implants
US11833272B2 (en) 2015-12-17 2023-12-05 Trustees Of Tufts College Silk-fibroin hydrogels, methods of forming, and uses thereof
JPWO2017110922A1 (ja) * 2015-12-25 2018-10-18 Ｓｐｉｂｅｒ株式会社 高分子凝集体の製造方法
RU2614694C1 (ru) * 2015-12-31 2017-03-28 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Средство, обладающее нейропротекторными свойствами в эксперименте и способ его получения
RU2616509C1 (ru) * 2015-12-31 2017-04-17 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ нейропротекции в эксперименте
CA3014301A1 (en) * 2016-02-12 2017-08-17 Spiber Technologies Ab Integrated cells
US10864299B2 (en) 2016-04-29 2020-12-15 Trustees Of Tufts College Artificial silk based innervated cornea
WO2017192227A1 (en) 2016-05-04 2017-11-09 Trustees Of Tufts College Silk nanofibrils and uses thereof
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
WO2018026853A1 (en) 2016-08-01 2018-02-08 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
MX2019001633A (es) 2016-08-12 2019-09-18 Silk Tech Ltd Proteina derivada de la seda para el tratamiento de la inflamacion.
US10857262B2 (en) 2016-10-31 2020-12-08 Sofregen Medical, Inc. Compositions comprising low molecular weight silk fibroin fragments and plasticizers
WO2019067745A1 (en) 2017-09-27 2019-04-04 Silk, Inc. SILK-COATED FABRICS, PRODUCTS AND PREPARATION METHODS THEREFOR
KR102017948B1 (ko) 2017-10-30 2019-09-03 단국대학교 천안캠퍼스 산학협력단 콜라겐 및 실크 피브로인을 포함하는 세포 캡슐화용 복합 하이드로겔 및 이의 제조방법
CN107892755B (zh) 2017-11-17 2019-04-02 苏州大学 一种生理条件下蚕丝蛋白溶液快速凝胶化的方法
RU2692578C1 (ru) * 2017-12-29 2019-06-25 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Имплантат для регенерации костной ткани и способ его получения
WO2019182099A1 (ja) * 2018-03-22 2019-09-26 国立大学法人 東京医科歯科大学 糖反応性複合ゲル組成物、その製造方法、前記糖反応性複合ゲル組成物を含むインスリン送達マイクロニードルおよびその製造方法
AU2019247655A1 (en) 2018-04-03 2020-10-01 Vaxess Technologies, Inc. Microneedle comprising silk fibroin applied to a dissolvable base
AU2020235627B2 (en) 2019-03-13 2026-01-08 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Acoustic extracellular matrix hydrogels and their use
CN110066418B (zh) * 2019-04-16 2021-08-31 苏州大学 一种活性丝素多孔材料或活性丝素膜及其制备方法
CN110150672A (zh) * 2019-06-03 2019-08-23 武汉轻工大学 硒补充剂及其制备方法
EP4045124A4 (en) 2019-10-15 2024-01-24 Sofregen Medical, Inc. DISPENSING DEVICES FOR DISPENSING AND METHOD FOR DISPENSING COMPOSITIONS
CN112322609A (zh) * 2020-11-25 2021-02-05 苏州大学 一种基于丝素蛋白的微藻固定化方法
CN112957521B (zh) * 2021-04-01 2022-06-10 浙江理工大学 一种载青蒿素脂质体的海藻酸盐-丝素蛋白复合水凝胶的制备方法
CN113842505A (zh) * 2021-09-13 2021-12-28 南通大学 用于神经修复的多孔双网络纳米导电水凝胶神经支架的制备方法
CN114958009B (zh) * 2022-05-24 2024-01-16 浙江理工大学 一种蚕丝基高强度离子凝胶柔性传感材料的制备方法
CA3260638A1 (en) 2022-06-24 2023-12-28 Terrestrial Bio, Inc. MEDICATION TAMP APPLICATOR
CN115260531B (zh) * 2022-08-04 2024-03-22 重庆科技学院 一种可自卷曲双层水凝胶片的制备方法
WO2024263835A1 (en) 2023-06-23 2024-12-26 Vaxess Technologies, Inc. Applicator for medicament patch
CN117099919B (zh) * 2023-08-11 2024-07-23 山东海之宝海洋科技有限公司 一种低卡深海小海带面的制备方法

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL29013C (https=) 1929-12-23
US3424164A (en) 1966-05-20 1969-01-28 Ethicon Inc Silk suture
JPS5838449B2 (ja) 1979-04-17 1983-08-23 カネボウ株式会社 微粉末状絹フィプロインの製造法
JPS5645961A (en) * 1979-09-20 1981-04-25 Kanebo Ltd Preparation of fibroin-coated pigment
JPS56163658A (en) * 1980-05-21 1981-12-16 Kanebo Ltd Manufacture of solid aromatic
JPS56166235A (en) 1980-05-24 1981-12-21 Kanebo Ltd Hydrophilic porous body and its preparation
JPS5765155A (en) 1980-10-09 1982-04-20 Kyowa Hakko Kogyo Co Ltd Preparation of powdery protein of soybean
JPS5838449A (ja) 1981-08-31 1983-03-05 Matsushita Electronics Corp 高圧ナトリウムランプ装置
JPS60142259A (ja) 1983-12-29 1985-07-27 Kanebo Ltd 固定化抗体
JPS60259677A (ja) 1984-05-31 1985-12-21 水島　繁三郎 動物蛋白吸着再生繊維からなる原糸、織物、編物及びその製造方法
US4798722A (en) 1986-11-12 1989-01-17 Zotos International, Inc. Permanent waving composition
CA1340581C (en) 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
JPS63190604A (ja) 1987-02-03 1988-08-08 Agency Of Ind Science & Technol 新規の水−アルコ−ル分離膜
US5606019A (en) 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
JPH0694518B2 (ja) 1987-11-02 1994-11-24 工業技術院長 絹フィブロイン多孔質体の製造方法
GB8800078D0 (en) 1988-01-05 1988-02-10 Ciba Geigy Ag Novel antibodies
JPH0284503A (ja) * 1988-09-20 1990-03-26 Agency Of Ind Science & Technol 絹フィブロインの凝固方法
JPH0296512A (ja) 1988-09-29 1990-04-09 Seiwa Kasei:Kk パーマネントウェーブ用第一剤
US5290494A (en) 1990-03-05 1994-03-01 Board Of Regents, The University Of Texas System Process of making a resorbable implantation device
US5989894A (en) 1990-04-20 1999-11-23 University Of Wyoming Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the DNA
GB2245279B (en) 1990-06-20 1993-04-07 Unilever Plc Shampoo composition
JP2854687B2 (ja) * 1990-07-30 1999-02-03 鐘紡株式会社 染色絹フィブロイン粉末の製造法
JPH04263611A (ja) 1991-02-16 1992-09-18 Pola Chem Ind Inc 水不溶性固形フィブロイン成形物及びその製造法
JPH0543600A (ja) 1991-08-08 1993-02-23 Kanebo Ltd 抗体または抗原固定化絹フイブロイン膜および免疫測定用センサー
JPH05163132A (ja) 1991-12-13 1993-06-29 Kanebo Ltd 皮膚化粧料
JPH0694518A (ja) 1992-09-10 1994-04-05 Toshiba Lighting & Technol Corp 日照センサ
JPH06346314A (ja) 1993-06-02 1994-12-20 Toyobo Co Ltd 再生絹フィブロイン繊維およびその製造方法
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
JPH08295697A (ja) 1995-04-26 1996-11-12 Kanebo Ltd 高濃度絹フィブロイン水溶液の製造方法
JPH1036676A (ja) 1996-07-26 1998-02-10 Kanebo Ltd タンパク質水溶液の濃縮方法
US6175053B1 (en) 1997-06-18 2001-01-16 Japan As Represented By Director General Of National Institute Of Sericultural And Entomological Science Ministry Of Agriculture, Forrestry And Fisheries Wound dressing material containing silk fibroin and sericin as main component and method for preparing same
WO1999001089A1 (en) 1997-07-01 1999-01-14 Brown University Research Foundation Implantable prosthetic devices coated with bioactive molecules
DE19732046A1 (de) 1997-07-25 1999-01-28 Abb Patent Gmbh Prozeßdiagnosesystem und Verfahren zur Diagnose von Vorgängen und Zuständen eines technischen Prozesses
US6123819A (en) 1997-11-12 2000-09-26 Protiveris, Inc. Nanoelectrode arrays
US5994099A (en) 1997-12-31 1999-11-30 The University Of Wyoming Extremely elastic spider silk protein and DNA coding therefor
DK1411075T3 (da) 1998-03-12 2008-10-27 Nektar Therapeutics Al Corp Fremgangsmåde til fremstilling af polymerkonjugater
US6110590A (en) 1998-04-15 2000-08-29 The University Of Akron Synthetically spun silk nanofibers and a process for making the same
US7662409B2 (en) 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US20030007991A1 (en) 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
JP2000202484A (ja) 1999-01-13 2000-07-25 Fuji Electric Co Ltd 有機性汚水の生物処理方法
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
JP3151665B2 (ja) 1999-03-23 2001-04-03 農林水産省蚕糸・昆虫農業技術研究所長 生体高分子／ポリアリルアミン複合体およびその製造方法
JP2000342902A (ja) 1999-06-07 2000-12-12 Ube Gosei Kogyo Kk 潮解を遅くした潮解性無機塩結晶の製造方法及び反応装置
AU1412201A (en) 1999-11-15 2001-05-30 Akira Hachimori Molecularly composite polymeric material of fibroin/cellulose and process for producing the same
EP1251888A1 (en) 2000-02-03 2002-10-30 Nexia Biotechnologies, Inc. Surgical sutures containing spider silk
IT1316885B1 (it) 2000-10-02 2003-05-13 Consorzio Per Gli Studi Uni Procedimento per la preparazione di un tessuto non tessuto in fibroinadi seta.
JP2002128691A (ja) 2000-10-24 2002-05-09 National Institute Of Agrobiological Sciences セリシン含有素材、その製造方法およびその使用方法
US7265186B2 (en) 2001-01-19 2007-09-04 Nektar Therapeutics Al, Corporation Multi-arm block copolymers as drug delivery vehicles
CN1247837C (zh) 2001-03-14 2006-03-29 东京农工大学长代表的日本国 丝和丝样材料的纤维和薄膜的制造方法
ITVR20010098A1 (it) 2001-09-11 2003-03-11 Consorzio Per Gli Studi Uni Procedimento per l'ottenimento di idrogeli di fibroina di seta.
JP4570363B2 (ja) 2001-10-02 2010-10-27 ノースウエスタン ユニヴァーシティ タンパク質およびペプチドのナノアレイ
GB0126118D0 (en) 2001-10-31 2002-01-02 Vollrath Friedrich W L Precursor feedstock for forming filaments
US6902932B2 (en) 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
JP4263611B2 (ja) 2001-12-07 2009-05-13 フィリップス ルミレッズ ライティング カンパニー リミテッド ライアビリティ カンパニー 小型の照明システム及びディスプレイ装置
JP3803962B2 (ja) 2001-12-28 2006-08-02 独立行政法人科学技術振興機構 絹タンパク質フィルムとその製造方法
US7057023B2 (en) 2002-01-11 2006-06-06 Nexia Biotechnologies Inc. Methods and apparatus for spinning spider silk protein
JP3772207B2 (ja) 2002-06-19 2006-05-10 独立行政法人農業生物資源研究所 生分解性生体高分子材料、その製造方法、およびこの高分子材料からなる機能性素材
EP2662211A1 (en) 2002-06-24 2013-11-13 Tufts University Silk biomaterials and methods of use thereof
CN1732014B (zh) 2002-11-01 2013-05-22 塔夫茨大学理事会 模板天然丝近晶状凝胶
WO2004062697A2 (en) 2003-01-07 2004-07-29 Tufts University Silk fibroin materials and use thereof
CA2562415C (en) 2003-04-10 2015-10-27 Tufts University Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
WO2005000483A1 (en) 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
CN1243059C (zh) * 2004-03-04 2006-02-22 苏州大学 纳米丝素颗粒的制造方法
US8178656B2 (en) 2004-06-11 2012-05-15 Trustees Of Tufts College Silk-based drug delivery system
US10010574B2 (en) 2004-07-31 2018-07-03 Brainguard Co., Ltd. Silk peptide for improving neuroprotective and neurofunctional effects and a method of its preparation
US20080280360A1 (en) 2004-10-12 2008-11-13 Trustees Of Tufts College Method for Producing Biomaterial Scaffolds
US7960509B2 (en) 2005-01-14 2011-06-14 Trustees Of Tufts College Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
US9290579B2 (en) 2005-04-20 2016-03-22 Trustees Of Tufts College Covalently immobilized protein gradients in three-dimensional porous scaffolds
ATE526378T1 (de) 2005-08-02 2011-10-15 Tufts College Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen
GB0516846D0 (en) 2005-08-17 2005-09-21 Knight David P Meniscal repair device
US20080058400A1 (en) 2006-08-29 2008-03-06 Fujifilm Corporation Skin external preparation
WO2008118133A2 (en) 2006-09-26 2008-10-02 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
GB2443401A (en) 2006-10-30 2008-05-07 Spin'tec Engineering Gmbh Producing fibres by extruding onto a treatment device
US20110121485A1 (en) 2006-10-30 2011-05-26 Spintec Engineering Gmbh Method and apparatus for the manufacture of a fiber
SI2089343T1 (sl) 2006-10-31 2011-10-28 Baseclick Gmbh Klik kemija za proizvodnjo poročevalskih molekul
US8529835B2 (en) 2006-11-03 2013-09-10 Tufts University Biopolymer sensor and method of manufacturing the same
US8195021B2 (en) 2006-11-03 2012-06-05 Tufts University/Trustees Of Tufts College Biopolymer optical waveguide and method of manufacturing the same
US20100068740A1 (en) 2006-11-03 2010-03-18 Trustees Of Tufts College Microfluidic device with a cylindrical microchannel and a method for fabricating same
WO2008118211A2 (en) 2006-11-03 2008-10-02 Trustees Of Tufts College Biopolymer photonic crystals and method of manufacturing the same
JP2010509645A (ja) 2006-11-03 2010-03-25 トラスティーズ オブ タフツ カレッジ ナノパターンが形成されたバイオポリマー光学デバイスおよびその製造方法
JP5163132B2 (ja) 2007-02-16 2013-03-13 ソニー株式会社 光ピックアップ装置、光ディスク装置、対物レンズの設計方法、光ピックアップ装置の設計方法、及び、光ディスク装置の設計方法
WO2008106485A2 (en) 2007-02-27 2008-09-04 Trustees Of Tufts College Tissue-engineered silk organs
JP4938093B2 (ja) 2007-03-23 2012-05-23 トムソン ライセンシング ２ｄ−ｔｏ−３ｄ変換のための２ｄ画像の領域分類のシステム及び方法
KR20100029217A (ko) 2007-05-29 2010-03-16 트러스티즈 오브 터프츠 칼리지 음파 처리를 이용한 실크 피브로인 겔화 방법
US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
CA2742844C (en) 2007-11-05 2017-02-28 Trustees Of Tufts College Fabrication of silk fibroin photonic structures by nanocontact imprinting
CA2713251A1 (en) 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
US8206774B2 (en) 2008-03-13 2012-06-26 Trustees Of Tufts College Diazonium salt modification of silk polymer
US9068282B2 (en) 2008-04-08 2015-06-30 Trustees Of Tufts College System and method for making biomaterial structures
MX341351B (es) 2008-05-15 2016-08-17 Tufts College Liberacion de adenosina basada en polimero de seda: potencial terapeutico para la epilepsia.
US20090297588A1 (en) 2008-05-28 2009-12-03 Spin'tec Engineering Gmbh Antibiotic dressing for the treatment of infected wounds
WO2009155397A2 (en) 2008-06-18 2009-12-23 Trustees Of Tufts College Edible holographic silk products
GB2461125A (en) 2008-06-25 2009-12-30 Spintec Engineering Gmbh A silk membrane for bone graft material
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
GB2464348A (en) 2008-10-17 2010-04-21 Spintec Engineering Gmbh Applying a liquid protein onto a permeable surface, and silk mono-filament having specific properties
EP2191867A1 (en) 2008-11-27 2010-06-02 KPSS-Kao Professional Salon Services GmbH Bleaching/Highlighting composition
EP2253336A1 (en) 2009-05-15 2010-11-24 Spintec Engineering GmbH A silk medical device with antimicrobial properties and a method of manufacture thereof
US20120171770A1 (en) 2009-07-10 2012-07-05 Trustees Of Tufts College Bioengineered silk protein-based nucleic acid delivery systems
KR101317420B1 (ko) 2010-03-11 2013-10-10 한국과학기술원 고분자량의 재조합 실크 또는 실크 유사 단백질 및 이를 이용하여 제조된 마이크로 또는 나노 크기의 거미줄 또는 거미줄 유사 섬유
JP6094518B2 (ja) * 2014-03-24 2017-03-15 株式会社富士通ゼネラル ヒートポンプ式暖房給湯装置

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