ATE515488T1 - Click-chemie zur herstellung von reportermolekülen - Google Patents
Click-chemie zur herstellung von reportermolekülenInfo
- Publication number
- ATE515488T1 ATE515488T1 AT07819506T AT07819506T ATE515488T1 AT E515488 T1 ATE515488 T1 AT E515488T1 AT 07819506 T AT07819506 T AT 07819506T AT 07819506 T AT07819506 T AT 07819506T AT E515488 T1 ATE515488 T1 AT E515488T1
- Authority
- AT
- Austria
- Prior art keywords
- reporter molecules
- click chemistry
- producing reporter
- producing
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85557406P | 2006-10-31 | 2006-10-31 | |
| PCT/EP2007/009474 WO2008052775A2 (en) | 2006-10-31 | 2007-10-31 | Click chemistry for the production of reporter molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE515488T1 true ATE515488T1 (de) | 2011-07-15 |
Family
ID=39344631
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07819506T ATE515488T1 (de) | 2006-10-31 | 2007-10-31 | Click-chemie zur herstellung von reportermolekülen |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8193335B2 (de) |
| EP (1) | EP2089343B1 (de) |
| JP (1) | JP5646172B2 (de) |
| CN (1) | CN101605743A (de) |
| AT (1) | ATE515488T1 (de) |
| AU (1) | AU2007315190B2 (de) |
| CA (1) | CA2667136A1 (de) |
| DK (1) | DK2089343T3 (de) |
| ES (1) | ES2369299T3 (de) |
| HR (1) | HRP20110554T1 (de) |
| PL (1) | PL2089343T3 (de) |
| PT (1) | PT2089343E (de) |
| SI (1) | SI2089343T1 (de) |
| WO (1) | WO2008052775A2 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20100659T1 (hr) | 2005-05-02 | 2011-01-31 | Baseclick Gmbh | Nove strategije obiljezavanja za osjetljivo otkrivanje analita |
| AU2006243370B2 (en) * | 2005-05-02 | 2012-06-28 | Basf Aktiengesellschaft | New labelling strategies for the sensitive detection of analytes |
| ES2369299T3 (es) | 2006-10-31 | 2011-11-29 | Baseclick Gmbh | Química de click para la producción de moléculas informadoras. |
| WO2008106485A2 (en) | 2007-02-27 | 2008-09-04 | Trustees Of Tufts College | Tissue-engineered silk organs |
| US8187616B2 (en) | 2007-05-29 | 2012-05-29 | Trustees Of Tufts College | Method for silk fibroin gelation using sonication |
| US8618297B2 (en) | 2008-07-25 | 2013-12-31 | Basf Se | Azide substituted naphthylene or rylene imide derivatives and their use as reagents in click-reactions |
| WO2010039548A2 (en) * | 2008-09-23 | 2010-04-08 | Alnylam Pharmaceuticals, Inc. | Chemical modifications of monomers and oligonucleotides with cycloaddition |
| US9150910B2 (en) | 2008-11-17 | 2015-10-06 | Headway Technologies, Inc. | Methods and compositions in particle-based detection of target molecules using linking molecules |
| EP2358898B1 (de) | 2008-11-17 | 2016-08-31 | Headway Technologies, Inc. | Verfahren und zusammensetzungen bei dem nachweis von zielmolekülen auf partikelbasis unter verwendung von kovalente bindungen ausbildenden reaktiven paaren |
| JP5569768B2 (ja) * | 2008-12-02 | 2014-08-13 | 国立大学法人九州大学 | ヌクレオシド三リン酸誘導体、核酸プローブ、マルチラベル化核酸プローブおよび標的核酸の検出方法 |
| EP2239053A1 (de) | 2009-04-09 | 2010-10-13 | baseclick GmbH | Click-Chemie auf heterogenen Katalysatoren |
| CA2775706A1 (en) | 2009-09-28 | 2011-03-31 | Trustees Of Tufts College | Drawn silk egel fibers and methods of making same |
| JP5937092B2 (ja) | 2010-10-19 | 2016-06-22 | トラスティーズ オブ タフツ カレッジ | シルクフィブロインベースのマイクロニードルおよびその製造方法 |
| CN102010508B (zh) * | 2010-10-19 | 2012-10-03 | 北京大学 | 一种阳离子聚合物及其制备方法和应用 |
| CN103476951B (zh) | 2011-02-16 | 2017-07-28 | 海德威技术公司 | 用于可检测的标记的靶标定位锚定的方法和组合物 |
| WO2012145652A1 (en) | 2011-04-20 | 2012-10-26 | Trustees Of Tufts College | Dynamic silk coatings for implantable devices |
| WO2013033705A2 (en) * | 2011-09-01 | 2013-03-07 | Case Western Reserve University | Non-natural nucleosides as theranostic agents |
| US9200121B2 (en) * | 2012-04-12 | 2015-12-01 | The Hong Kong University Of Science And Technology | Thermosetting poly(siloxane-diphenylbutadiyne) with readily tunable glass transition temperature and high thermal stability |
| BR112015000236A2 (pt) | 2012-07-10 | 2017-06-27 | Baseclick Gmbh | moléculas de ácidos nucleicos modificadas por anandamida |
| CA2891966A1 (en) | 2012-12-20 | 2014-06-26 | Sirna Therapeutics, Inc. | Post-synthetic orthogonal amidation plus metal catalyzed azide-alkyne cycloaddition click chemistry on sirna |
| WO2015012912A2 (en) * | 2013-04-22 | 2015-01-29 | Northwestern University | Alkyne phosphoramidites and preparation of spherical nucleic acid constructs |
| WO2015026663A1 (en) * | 2013-08-19 | 2015-02-26 | University Of Houston | Phosphorescent reporters |
| WO2015088990A1 (en) | 2013-12-09 | 2015-06-18 | Durect Corporation | Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same |
| AU2015349730C1 (en) * | 2014-11-20 | 2020-04-30 | F. Hoffmann-La Roche Ag | Nulceoside phosphoroamidate esters and derivatives thereof, use and synthesis thereof |
| JP6667179B2 (ja) * | 2015-03-24 | 2020-03-18 | 国立大学法人岐阜大学 | オリゴヌクレオチド誘導体及びそれを用いたオリゴヌクレオチド構築物並びにそれらの製造方法 |
| EP3472376A4 (de) | 2016-06-16 | 2019-12-18 | Richard Edward Watts | Oligonukleotidgesteuerte und aufgezeichnete kombinatorische synthese von codierten sondenmolekülen |
| EP3619340A4 (de) | 2017-05-02 | 2021-01-20 | Haystack Sciences Corporation | Moleküle zur verifizierung von oligonukleotidgerichteter kombinatorischer synthese und verfahren zur herstellung und verwendung davon |
| CN109490523A (zh) * | 2018-10-22 | 2019-03-19 | 北京纳晶生物科技有限公司 | 用于标记的纳米材料、核酸探针及核酸与纳米材料偶联的方法 |
| CN112305227A (zh) * | 2019-07-31 | 2021-02-02 | 深圳市帝迈生物技术有限公司 | 自交联蛋白、配体组合物、制备方法、试剂盒及系统 |
| CN111018930A (zh) * | 2019-12-06 | 2020-04-17 | 深圳大学 | Tpe-2’-脱氧核苷、荧光凝胶及其制备方法与应用 |
| US20260007869A1 (en) | 2023-06-23 | 2026-01-08 | Vaxess Technologies, Inc. | Microneedle array patches (maps), systems, and methods for manufacturing and using same |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2209754A (en) | 1987-09-17 | 1989-05-24 | Thomas Lee Mattson | Polyaldehydic polynucleotides in use as probes,their preparation and use |
| JP2681061B2 (ja) | 1988-06-08 | 1997-11-19 | ロンドン・ダイアグノスティック・インコーポレーテッド | 検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ |
| US5723289A (en) | 1990-06-11 | 1998-03-03 | Nexstar Pharmaceuticals, Inc. | Parallel selex |
| US5843650A (en) | 1995-05-01 | 1998-12-01 | Segev; David | Nucleic acid detection and amplification by chemical linkage of oligonucleotides |
| EP2319854B1 (de) | 1997-01-08 | 2016-11-30 | Sigma-Aldrich Co. LLC | Biokonjugation von Makromolekülen |
| US7427678B2 (en) | 1998-01-08 | 2008-09-23 | Sigma-Aldrich Co. | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
| US7205105B2 (en) | 1999-12-08 | 2007-04-17 | Epoch Biosciences, Inc. | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis |
| US6727356B1 (en) | 1999-12-08 | 2004-04-27 | Epoch Pharmaceuticals, Inc. | Fluorescent quenching detection reagents and methods |
| DE10013600A1 (de) | 2000-03-18 | 2002-01-10 | Aventis Res & Tech Gmbh & Co | Reaktive Monomere für die Oligonucleotid- und Polynucleotidsynthese, modifizierte Oligonucleotide und Polynucleotiden und ein Verfahren zu deren Herstellung |
| WO2003079014A1 (en) | 2002-03-03 | 2003-09-25 | Activx Biosciences, Inc. | Tethered activity-based probes and uses thereof |
| US7375234B2 (en) | 2002-05-30 | 2008-05-20 | The Scripps Research Institute | Copper-catalysed ligation of azides and acetylenes |
| WO2004055160A2 (en) | 2002-12-13 | 2004-07-01 | The Trustees Of Columbia University In The City Of New York | Biomolecular coupling methods using 1,3-dipolar cycloaddition chemistry |
| KR100540509B1 (ko) | 2004-01-07 | 2006-01-11 | 학교법인 포항공과대학교 | 수화젤레이터로 사용되는 2'-데옥시우리딘 유도체 |
| US7745118B2 (en) | 2004-04-08 | 2010-06-29 | Roche Nimblegen, Inc. | Comparative genomic resequencing |
| KR20080000620A (ko) | 2005-04-27 | 2008-01-02 | 지멘스 메디컬 솔루션즈 유에스에이, 인크. | 분자 이미징 프로브를 합성하기 위한 클릭 화학 방법 |
| AU2006243370B2 (en) * | 2005-05-02 | 2012-06-28 | Basf Aktiengesellschaft | New labelling strategies for the sensitive detection of analytes |
| EP1937849B1 (de) | 2005-10-27 | 2019-05-29 | The President and Fellows of Harvard College | Verfahren und zusammensetzungen zur markierung von nukleinsäuren |
| ES2369299T3 (es) | 2006-10-31 | 2011-11-29 | Baseclick Gmbh | Química de click para la producción de moléculas informadoras. |
-
2007
- 2007-10-31 ES ES07819506T patent/ES2369299T3/es active Active
- 2007-10-31 AU AU2007315190A patent/AU2007315190B2/en not_active Ceased
- 2007-10-31 PL PL07819506T patent/PL2089343T3/pl unknown
- 2007-10-31 DK DK07819506.2T patent/DK2089343T3/da active
- 2007-10-31 PT PT07819506T patent/PT2089343E/pt unknown
- 2007-10-31 CA CA002667136A patent/CA2667136A1/en not_active Abandoned
- 2007-10-31 SI SI200730721T patent/SI2089343T1/sl unknown
- 2007-10-31 US US12/447,526 patent/US8193335B2/en active Active
- 2007-10-31 HR HR20110554T patent/HRP20110554T1/hr unknown
- 2007-10-31 EP EP07819506A patent/EP2089343B1/de active Active
- 2007-10-31 CN CNA2007800405932A patent/CN101605743A/zh active Pending
- 2007-10-31 WO PCT/EP2007/009474 patent/WO2008052775A2/en not_active Ceased
- 2007-10-31 JP JP2009533756A patent/JP5646172B2/ja not_active Expired - Fee Related
- 2007-10-31 AT AT07819506T patent/ATE515488T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| US8193335B2 (en) | 2012-06-05 |
| DK2089343T3 (da) | 2011-10-24 |
| WO2008052775A3 (en) | 2009-01-15 |
| EP2089343A2 (de) | 2009-08-19 |
| AU2007315190A1 (en) | 2008-05-08 |
| JP5646172B2 (ja) | 2014-12-24 |
| SI2089343T1 (sl) | 2011-10-28 |
| CA2667136A1 (en) | 2008-05-08 |
| ES2369299T3 (es) | 2011-11-29 |
| JP2010508015A (ja) | 2010-03-18 |
| EP2089343B1 (de) | 2011-07-06 |
| PL2089343T3 (pl) | 2011-12-30 |
| US20100081137A1 (en) | 2010-04-01 |
| AU2007315190B2 (en) | 2012-05-31 |
| WO2008052775A2 (en) | 2008-05-08 |
| CN101605743A (zh) | 2009-12-16 |
| PT2089343E (pt) | 2011-09-06 |
| HRP20110554T1 (hr) | 2011-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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