ATE526378T1 - Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen - Google Patents

Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen

Info

Publication number
ATE526378T1
ATE526378T1 AT06813260T AT06813260T ATE526378T1 AT E526378 T1 ATE526378 T1 AT E526378T1 AT 06813260 T AT06813260 T AT 06813260T AT 06813260 T AT06813260 T AT 06813260T AT E526378 T1 ATE526378 T1 AT E526378T1
Authority
AT
Austria
Prior art keywords
coatings
silk fibroin
methods
layered
deposition
Prior art date
Application number
AT06813260T
Other languages
English (en)
Inventor
David Kaplan
Xianyan Wang
Original Assignee
Tufts College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37603233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE526378(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tufts College filed Critical Tufts College
Application granted granted Critical
Publication of ATE526378T1 publication Critical patent/ATE526378T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D189/00—Coating compositions based on proteins; Coating compositions based on derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31725—Of polyamide
    • Y10T428/31768—Natural source-type polyamide [e.g., casein, gelatin, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Paints Or Removers (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
AT06813260T 2005-08-02 2006-07-28 Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen ATE526378T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70462205P 2005-08-02 2005-08-02
US72883705P 2005-10-21 2005-10-21
PCT/US2006/029826 WO2007016524A2 (en) 2005-08-02 2006-07-28 Methods for stepwise deposition of silk fibroin coatings

Publications (1)

Publication Number Publication Date
ATE526378T1 true ATE526378T1 (de) 2011-10-15

Family

ID=37603233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06813260T ATE526378T1 (de) 2005-08-02 2006-07-28 Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen

Country Status (6)

Country Link
US (4) US8354501B2 (de)
EP (1) EP1915436B1 (de)
AT (1) ATE526378T1 (de)
CA (1) CA2645934C (de)
ES (1) ES2374428T3 (de)
WO (1) WO2007016524A2 (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2662211A1 (de) * 2002-06-24 2013-11-13 Tufts University Seidenbiomaterialien und Verfahren zu ihrer Verwendung
WO2004062697A2 (en) 2003-01-07 2004-07-29 Tufts University Silk fibroin materials and use thereof
CA2562415C (en) 2003-04-10 2015-10-27 Tufts University Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
CN102683391B (zh) 2004-06-04 2015-11-18 伊利诺伊大学评议会 用于制造并组装可印刷半导体元件的方法和设备
ATE526378T1 (de) 2005-08-02 2011-10-15 Tufts College Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen
US8529835B2 (en) * 2006-11-03 2013-09-10 Tufts University Biopolymer sensor and method of manufacturing the same
US8195021B2 (en) 2006-11-03 2012-06-05 Tufts University/Trustees Of Tufts College Biopolymer optical waveguide and method of manufacturing the same
JP2010509645A (ja) 2006-11-03 2010-03-25 トラスティーズ オブ タフツ カレッジ ナノパターンが形成されたバイオポリマー光学デバイスおよびその製造方法
WO2008108838A2 (en) * 2006-11-21 2008-09-12 Charles Stark Draper Laboratory, Inc. Microfluidic devices and methods for fabricating the same
WO2008106485A2 (en) 2007-02-27 2008-09-04 Trustees Of Tufts College Tissue-engineered silk organs
KR20100029217A (ko) 2007-05-29 2010-03-16 트러스티즈 오브 터프츠 칼리지 음파 처리를 이용한 실크 피브로인 겔화 방법
US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
CN101406713B (zh) * 2007-10-12 2012-09-19 微创医疗器械(上海)有限公司 一种人工血管支架及其制备方法
CA2713251A1 (en) * 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
US8206774B2 (en) * 2008-03-13 2012-06-26 Trustees Of Tufts College Diazonium salt modification of silk polymer
US9068282B2 (en) * 2008-04-08 2015-06-30 Trustees Of Tufts College System and method for making biomaterial structures
MX341351B (es) * 2008-05-15 2016-08-17 Tufts College Liberacion de adenosina basada en polimero de seda: potencial terapeutico para la epilepsia.
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
US9289132B2 (en) 2008-10-07 2016-03-22 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
US20110223153A1 (en) 2008-10-09 2011-09-15 Trustees Of Tufts College Modified silk films containing glycerol
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
EP2421551B2 (de) * 2009-04-20 2020-07-15 Allergan, Inc. Seiden-fibroin-hydrogele und ihre verwendungen
US9861725B2 (en) 2009-05-28 2018-01-09 Addbio Ab Multilayer protein films, methods of making, and drug delivery devices and biomedical implants employing the films
WO2011008842A2 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
US9440005B2 (en) * 2009-08-21 2016-09-13 National Institute Of Agrobiological Sciences Substrate for feeding cells and/or tissues, cell/tissue-feeder and method for the production of the same, method for the regeneration of tissues, and method for the production of porous bodies
CA2775706A1 (en) 2009-09-28 2011-03-31 Trustees Of Tufts College Drawn silk egel fibers and methods of making same
EP2483199B1 (de) 2009-09-29 2017-04-26 Trustees Of Tufts College Seidenanokügelchen und -mikrokügelchen sowie verfahren zu ihrer herstellung
US9723122B2 (en) 2009-10-01 2017-08-01 Mc10, Inc. Protective cases with integrated electronics
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US10918298B2 (en) 2009-12-16 2021-02-16 The Board Of Trustees Of The University Of Illinois High-speed, high-resolution electrophysiology in-vivo using conformal electronics
US9936574B2 (en) 2009-12-16 2018-04-03 The Board Of Trustees Of The University Of Illinois Waterproof stretchable optoelectronics
US8666471B2 (en) 2010-03-17 2014-03-04 The Board Of Trustees Of The University Of Illinois Implantable biomedical devices on bioresorbable substrates
US9603971B2 (en) 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
EP2544598B1 (de) 2010-03-12 2020-05-06 The Board of Trustees of the University of Illionis Wasserfeste dehnbare optoelektronische elemente
JP2013533754A (ja) 2010-04-12 2013-08-29 タフツ・ユニバーシティ 絹電子部品
EP2611473A4 (de) 2010-09-01 2014-08-13 Tufts College Seidenfibroin und polyethylenglykol-biomaterialien
US9517357B2 (en) 2010-09-03 2016-12-13 Tufts University Plasmonic nanoparticle-doped silk materials
US9761789B2 (en) 2010-09-27 2017-09-12 Tufts University Silk-based piezoelectric materials
WO2012054582A2 (en) 2010-10-19 2012-04-26 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
CN103348358A (zh) * 2010-11-12 2013-10-09 Abbvie公司 用于确定测试物质对活细胞作用的高通量光学方法及系统
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
AU2012245198B2 (en) * 2011-04-21 2017-07-13 Trustees Of Tufts College Compositions and methods for stabilization of active agents
WO2012158709A1 (en) 2011-05-16 2012-11-22 The Board Of Trustees Of The University Of Illinois Thermally managed led arrays assembled by printing
US9159635B2 (en) 2011-05-27 2015-10-13 Mc10, Inc. Flexible electronic structure
US8934965B2 (en) 2011-06-03 2015-01-13 The Board Of Trustees Of The University Of Illinois Conformable actively multiplexed high-density surface electrode array for brain interfacing
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
ES2791769T3 (es) 2011-11-09 2020-11-05 Tufts College Espumas de fibroína de seda inyectables y usos de la misma
CA2890366A1 (en) 2011-11-09 2013-05-16 Trustees Of Tufts College Injectable silk fibroin particles and uses thereof
CN108389893A (zh) 2011-12-01 2018-08-10 伊利诺伊大学评议会 经设计以经历可编程转变的瞬态器件
WO2013130156A2 (en) 2011-12-05 2013-09-06 Tufts University Signal enhancement by silk photonic crystals
BR112014016154A8 (pt) 2011-12-29 2017-07-04 Tufts College funcionalização de biomateriais para controlar respostas à regeneração e inflamação
US10912862B2 (en) 2012-02-06 2021-02-09 Children's Medical Center Corporation Multi-layer biomaterial for tissue regeneration and wound healing
EP2830492B1 (de) 2012-03-30 2021-05-19 The Board of Trustees of the University of Illinois An ein körperteil montierbare, oberflächenkonformierbare, elektronische vorrichtungen und zugehöriges herstellungsverfahren
US9925301B2 (en) 2012-04-06 2018-03-27 Trustees Of Tufts College Methods of producing and using silk microfibers
EP2836236B1 (de) 2012-04-13 2019-01-02 Trustees Of Tufts College Verfahren und zusammensetzungen zur herstellung einer seidenmikrokugel
WO2013163407A1 (en) 2012-04-25 2013-10-31 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
JP2015536919A (ja) * 2012-10-11 2015-12-24 タフツ ユニバーシティー 抗癌剤の持続送達のためのシルクリザーバ
US9925299B2 (en) 2012-10-26 2018-03-27 Tufts University Silk-based fabrication techniques to prepare high strength calcium phosphate ceramic scaffolds
WO2014077881A1 (en) * 2012-11-14 2014-05-22 Hollister Incorporated Urinary catheters having varying flexibility
WO2014085725A1 (en) 2012-11-27 2014-06-05 Tufts University Biopolymer-based inks and use thereof
US20150368417A1 (en) * 2013-02-15 2015-12-24 Tufts University Silk-based nanoimprinting
WO2014197093A2 (en) 2013-03-15 2014-12-11 Tufts University All water-based nanopatterning
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US10464361B2 (en) 2013-03-15 2019-11-05 Tufts University Silk water lithography
US10292263B2 (en) 2013-04-12 2019-05-14 The Board Of Trustees Of The University Of Illinois Biodegradable materials for multilayer transient printed circuit boards
WO2014169170A1 (en) 2013-04-12 2014-10-16 The Board Of Trustees Of The University Of Illinois Inorganic and organic transient electronic devices
WO2014190005A1 (en) 2013-05-22 2014-11-27 Transient Electronics, Inc. Controlled transformation of non-transient electronics
US20160089854A1 (en) * 2013-05-24 2016-03-31 Tufts University Interface control of semi-crystalline biopolymer films
WO2015027144A1 (en) * 2013-08-22 2015-02-26 Allergan, Inc. Implantable medical devices
WO2015048527A1 (en) 2013-09-27 2015-04-02 Tufts University Optically transparent silk hydrogels
WO2015054125A1 (en) 2013-10-08 2015-04-16 Trustees Of Tufts College Tunable covalently crosslinked hydrogels and methods of making the same
US10513802B2 (en) 2013-11-08 2019-12-24 Tufts University Peptide-based nanofibrillar materials
US20170258404A1 (en) * 2014-11-25 2017-09-14 Diagnostic Biochips, Inc. Coated Biosensor and Method for Preserving Biosensor During Implantation into the Brain or Other Tissues
EA035551B1 (ru) 2014-12-02 2020-07-06 Силк Терапьютикс, Инк. Изделие
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
EP3268381B1 (de) 2015-03-12 2022-03-02 Tufts University Formgedächtnis-seidenmaterialen
CN107851208B (zh) 2015-06-01 2021-09-10 伊利诺伊大学评议会 具有无线供电和近场通信能力的小型化电子系统
WO2016196673A1 (en) 2015-06-01 2016-12-08 The Board Of Trustees Of The University Of Illinois Alternative approach to uv sensing
AU2016294611B2 (en) * 2015-07-14 2022-08-11 Evolved By Nature, Inc. Silk performance apparel and products and methods of preparing the same
US20200054792A1 (en) 2015-07-28 2020-02-20 Trustees Of Tufts College Polypeptide monoliths
US10925543B2 (en) 2015-11-11 2021-02-23 The Board Of Trustees Of The University Of Illinois Bioresorbable silicon electronics for transient implants
US11833272B2 (en) 2015-12-17 2023-12-05 Trustees Of Tufts College Silk-fibroin hydrogels, methods of forming, and uses thereof
CA3024270A1 (en) 2016-05-16 2017-11-23 Spiber Technologies Ab Spider silk coating of solid surfaces
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
WO2018013612A1 (en) * 2016-07-11 2018-01-18 Trustees Of Tufts College Artificial brain tissue
WO2018026853A1 (en) 2016-08-01 2018-02-08 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
US10857262B2 (en) 2016-10-31 2020-12-08 Sofregen Medical, Inc. Compositions comprising low molecular weight silk fibroin fragments and plasticizers
EP3600463B1 (de) * 2017-03-23 2022-03-02 Council of Scientific and Industrial Research Verfahren zur beschichtung eines biomedizinischen implantats mit einem biokompatiblen polymer und biomedizinisches implantat daraus
US12059826B2 (en) 2017-09-26 2024-08-13 Spiber Technologies Ab Structuring of surface-active macromolecules
WO2019067745A1 (en) 2017-09-27 2019-04-04 Silk, Inc. SILK-COATED FABRICS, PRODUCTS AND PREPARATION METHODS THEREFOR
AU2019247655A1 (en) 2018-04-03 2020-10-01 Vaxess Technologies, Inc. Microneedle comprising silk fibroin applied to a dissolvable base
CN113412061A (zh) * 2018-12-10 2021-09-17 剑桥谷物公司 用于基于聚合物的保质期延长的组合物和方法
TWI691531B (zh) * 2019-02-11 2020-04-21 南臺學校財團法人南臺科技大學 蠶絲蛋白膜的製造方法
US11779683B2 (en) 2019-04-08 2023-10-10 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11369473B2 (en) 2019-04-08 2022-06-28 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
AU2020288624B2 (en) 2019-06-04 2025-09-25 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
WO2021046520A1 (en) * 2019-09-06 2021-03-11 Zha Runye Helen Methods for generating surface coatings via self-assembly of silk fibroin and silk fibroin-like macromolecules
EP4045124A4 (de) 2019-10-15 2024-01-24 Sofregen Medical, Inc. Abgabevorrichtungen für die abgabe und verfahren zur abgabe von zusammensetzungen
CN112043877B (zh) * 2020-08-06 2022-10-14 苏州大学 一种蚕丝抗凝血管支架覆膜及其制备方法
US11976196B2 (en) 2021-04-14 2024-05-07 Cambridge Crops, Inc. Silk packaging applications
JP7695344B2 (ja) 2021-05-21 2025-06-18 ケンブリッジ クロップス インコーポレイテッド． ドゥーイングビジネスアズ モリ 絹フィブロイン溶液及び絹フィブロインを含む粉末を製造するためのシステム及び方法
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin
CA3260638A1 (en) 2022-06-24 2023-12-28 Terrestrial Bio, Inc. MEDICATION TAMP APPLICATOR
WO2024263835A1 (en) 2023-06-23 2024-12-26 Vaxess Technologies, Inc. Applicator for medicament patch
CN117445491A (zh) * 2023-12-06 2024-01-26 江西丝科生物科技有限公司 一种蛋白膜的复合方法及复合蛋白膜
CN120737363B (zh) * 2025-09-05 2025-11-21 苏州贝彩纳米科技有限公司 一种丝素蛋白基压电材料及其制备方法与应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2685570A (en) 1952-02-28 1954-08-03 Verdiers Edward Erlick Process for precipitating synthetic polyamides in combination with silk fiber
US3424164A (en) 1966-05-20 1969-01-28 Ethicon Inc Silk suture
KR100351260B1 (ko) * 1993-05-24 2002-11-08 이데미쓰세끼유가가꾸가부시끼가이샤 천연유기물미분말함유물
CN1150315C (zh) * 1997-11-18 2004-05-19 独立行政法人农业生物资源研究所 表皮细胞的增殖活性化材料
JPH11243948A (ja) 1998-03-02 1999-09-14 Natl Inst Of Sericultural & Entomological Science 動物細胞増殖用の細胞培養床基材及びその調製方法
GB9806530D0 (en) * 1998-03-26 1998-05-27 Glaxo Group Ltd Inflammatory mediator
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US20030007991A1 (en) * 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
JP2005513162A (ja) * 2001-10-02 2005-05-12 トラスティーズ オブ タフツ カレッジ 自己集合性ポリマ及びそれから作製される材料
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
JP3803962B2 (ja) 2001-12-28 2006-08-02 独立行政法人科学技術振興機構 絹タンパク質フィルムとその製造方法
JP3772207B2 (ja) * 2002-06-19 2006-05-10 独立行政法人農業生物資源研究所 生分解性生体高分子材料、その製造方法、およびこの高分子材料からなる機能性素材
EP2662211A1 (de) * 2002-06-24 2013-11-13 Tufts University Seidenbiomaterialien und Verfahren zu ihrer Verwendung
CA2562415C (en) * 2003-04-10 2015-10-27 Tufts University Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
AU2004289362A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
US20050148512A1 (en) * 2003-11-10 2005-07-07 Angiotech International Ag Medical implants and fibrosis-inducing agents
US8178656B2 (en) * 2004-06-11 2012-05-15 Trustees Of Tufts College Silk-based drug delivery system
JP5475234B2 (ja) * 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド 医薬化合物
US20090088679A1 (en) * 2005-02-07 2009-04-02 Massachusetts Institute Of Technology Electronically-Degradable Layer-by-Layer Thin Films
CN100368026C (zh) 2005-07-01 2008-02-13 复旦大学附属华山医院 一种丝素蛋白涂层钛网及其制备方法和应用
ATE526378T1 (de) 2005-08-02 2011-10-15 Tufts College Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen
US20100150991A1 (en) 2008-12-15 2010-06-17 Bernstein Brent H Combination Wound Therapy
US9732321B2 (en) * 2010-02-16 2017-08-15 The General Hospital Corporation Engineered craniofacial constructs with composite scaffold
JP2013533754A (ja) 2010-04-12 2013-08-29 タフツ・ユニバーシティ 絹電子部品
US9925301B2 (en) 2012-04-06 2018-03-27 Trustees Of Tufts College Methods of producing and using silk microfibers

Also Published As

Publication number Publication date
ES2374428T3 (es) 2012-02-16
US20150231311A1 (en) 2015-08-20
EP1915436A2 (de) 2008-04-30
WO2007016524A3 (en) 2007-04-05
US9731052B2 (en) 2017-08-15
US20090202614A1 (en) 2009-08-13
WO2007016524A2 (en) 2007-02-08
CA2645934C (en) 2014-04-29
CA2645934A1 (en) 2007-02-08
EP1915436B1 (de) 2011-09-28
US20130287835A1 (en) 2013-10-31
US8354501B2 (en) 2013-01-15
US20130156844A1 (en) 2013-06-20

Similar Documents

Publication Publication Date Title
ATE526378T1 (de) Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen
Guo et al. Controlling cell adhesion using layer-by-layer approaches for biomedical applications
Bazaka et al. Do bacteria differentiate between degrees of nanoscale surface roughness?
Chen et al. Preparation of super-hydrophobic surface on stainless steel
Tserepi et al. Plasma nanotextured polymeric surfaces for controlling cell attachment and proliferation: a short review
Neirinck et al. A current opinion on electrophoretic deposition in pulsed and alternating fields
FR2893266B1 (fr) Produit superhydrophile ou superhydrophobe, procede pour sa realisation et utilisation de ce produit
WO2011156596A3 (en) Articles having non-fouling surfaces and processes for preparing the same including pretreatment of substrates
AU2017271673A1 (en) Covalently modified surfaces, kits, and methods of preparation and use
WO2009076572A3 (en) Methods of making an article and articles
WO2011012935A3 (en) Photocatalytic coating for the controlled release of volatile agents
BR102013032886B8 (pt) composição de duas partes curável por umidade, método para revestir um substrato, e, artigo revestido
EA200801383A1 (ru) Получение наноразмерных материалов
WO2007064597A3 (en) Uniform surfaces for hybrid material substrates and methods for making and using same
Meng et al. Recent progress in biointerfaces with controlled bacterial adhesion by using chemical and physical methods
WO2015042393A3 (en) Evolved sortases and uses thereof
MX2009010357A (es) Materiales para remover contaminantes de fluidos utilizando soportes con grupos derivados funcionalizados biologicamente y los metodos de formacion y uso de los mismos.
ATE469364T1 (de) Prozess zum beschichten eines optischen artikels mit einer anti-fouling-oberflächenbeschichtung durch unterdruckverdampfung
ATE546127T1 (de) Polymerbeschichteter glasfüllstoff zur verwendung in dentalwerkstoffen
TW200724616A (en) Compositions containing a silanol functional polymer and related hydrophilic coating films
DE102005001078A8 (de) Glaspulver, insbesondere biologisch aktives Glaspulver und Verfahren zur Herstellung von Glaspulver, insbesondere biologisch aktivem Glaspulver
Wang et al. Electrostatic adsorption behavior of zwitterionic copolymers on negatively charged surfaces
ATE494322T1 (de) Hydrophiler überzug und herstellungsverfahren dafür
WO2006110540A3 (en) Antimicrobial polymer coatings and a method producing them via chemical vapour deposition
Kim et al. Long‐term stable hydrophilic surface modification of poly (ether ether ketone) via the multilayered chemical grafting method

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties