HUE053953T2 - Heterociklusos aminok mint PI3K-gátlók - Google Patents

Heterociklusos aminok mint PI3K-gátlók

Info

Publication number
HUE053953T2
HUE053953T2 HUE18215449A HUE18215449A HUE053953T2 HU E053953 T2 HUE053953 T2 HU E053953T2 HU E18215449 A HUE18215449 A HU E18215449A HU E18215449 A HUE18215449 A HU E18215449A HU E053953 T2 HUE053953 T2 HU E053953T2
Authority
HU
Hungary
Prior art keywords
heterocyclic amines
pi3k inhibitors
pi3k
inhibitors
heterocyclic
Prior art date
Application number
HUE18215449A
Other languages
English (en)
Hungarian (hu)
Inventor
Yun-Long Li
Wenqing Yao
Andrew Combs
Eddy Yue
Song Mei
Wenyu Zhu
Joseph Glenn
Thomas Maduskuie
Richard Sparks
Brent Douty
Chunhong He
Original Assignee
Incyte Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Holdings Corp filed Critical Incyte Holdings Corp
Publication of HUE053953T2 publication Critical patent/HUE053953T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HUE18215449A 2011-09-02 2012-08-31 Heterociklusos aminok mint PI3K-gátlók HUE053953T2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161530866P 2011-09-02 2011-09-02
US201261594882P 2012-02-03 2012-02-03
US201261677445P 2012-07-30 2012-07-30

Publications (1)

Publication Number Publication Date
HUE053953T2 true HUE053953T2 (hu) 2021-08-30

Family

ID=47071429

Family Applications (3)

Application Number Title Priority Date Filing Date
HUE18215449A HUE053953T2 (hu) 2011-09-02 2012-08-31 Heterociklusos aminok mint PI3K-gátlók
HUE16199883A HUE043703T2 (hu) 2011-09-02 2012-08-31 Heterociklusos aminok PI3K inhibitorokként
HUE12775861A HUE030869T2 (en) 2011-09-02 2012-08-31 Heterocyclylamines as pi3k inhibitors

Family Applications After (2)

Application Number Title Priority Date Filing Date
HUE16199883A HUE043703T2 (hu) 2011-09-02 2012-08-31 Heterociklusos aminok PI3K inhibitorokként
HUE12775861A HUE030869T2 (en) 2011-09-02 2012-08-31 Heterocyclylamines as pi3k inhibitors

Country Status (37)

Country Link
US (10) US9199982B2 (enExample)
EP (4) EP2751109B1 (enExample)
JP (9) JP6067709B2 (enExample)
KR (7) KR102507287B1 (enExample)
CN (1) CN106986867B (enExample)
AR (1) AR087760A1 (enExample)
AU (6) AU2012301721B2 (enExample)
BR (2) BR122019020716B1 (enExample)
CA (1) CA2846652C (enExample)
CL (1) CL2014000517A1 (enExample)
CO (1) CO6910199A2 (enExample)
CR (2) CR20180293A (enExample)
CY (3) CY1118679T1 (enExample)
DK (3) DK3196202T3 (enExample)
EA (2) EA028890B1 (enExample)
EC (1) ECSP14013274A (enExample)
ES (4) ES3036260T3 (enExample)
HR (3) HRP20170285T1 (enExample)
HU (3) HUE053953T2 (enExample)
IL (7) IL299533B2 (enExample)
LT (3) LT2751109T (enExample)
ME (2) ME03397B (enExample)
MX (3) MX389479B (enExample)
MY (1) MY179332A (enExample)
NZ (1) NZ769326A (enExample)
PE (2) PE20181272A1 (enExample)
PH (4) PH12014500470B1 (enExample)
PL (3) PL2751109T3 (enExample)
PT (3) PT3196202T (enExample)
RS (3) RS58817B1 (enExample)
SG (3) SG11201400232WA (enExample)
SI (3) SI3513793T1 (enExample)
SM (4) SMT201700111T1 (enExample)
TW (6) TWI673272B (enExample)
UA (1) UA121539C2 (enExample)
WO (1) WO2013033569A1 (enExample)
ZA (1) ZA201904877B (enExample)

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